LOCUS       DAXQKX010000001       120341 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.001, whole genome shotgun sequence.
ACCESSION   DAXQKX010000001 DAXQKX010000000
VERSION     DAXQKX010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 120341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 120341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..120341
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.001"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(554..2167)
                     /locus_tag="ACF3MF_000001"
     CDS             complement(554..2167)
                     /locus_tag="ACF3MF_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFE3926041.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
     gene            complement(2308..3216)
                     /locus_tag="ACF3MF_000002"
     CDS             complement(2308..3216)
                     /locus_tag="ACF3MF_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFE3926042.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSEKFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            3399..4523
                     /locus_tag="ACF3MF_000003"
     CDS             3399..4523
                     /locus_tag="ACF3MF_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFE3926043.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            4750..5667
                     /locus_tag="ACF3MF_000004"
     CDS             4750..5667
                     /locus_tag="ACF3MF_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFE3926044.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            5660..6493
                     /locus_tag="ACF3MF_000005"
     CDS             5660..6493
                     /locus_tag="ACF3MF_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFE3926045.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            6576..7694
                     /locus_tag="ACF3MF_000006"
     CDS             6576..7694
                     /locus_tag="ACF3MF_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFE3926046.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            7715..9586
                     /locus_tag="ACF3MF_000007"
     CDS             7715..9586
                     /locus_tag="ACF3MF_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HFE3926047.1"
                     /translation="MKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQIDYIHQGVG
                     YGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYWGEIHERDQR
                     MVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQFFKIIVGTII
                     QKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYGLIYSVLEPE
                     KPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAMLWADLLPFKL
                     GEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLWLNKIFLLLA
                     LPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPNFHTLTNEKY
                     LKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKTYGQFIVRNN
                     VRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLYETGFAIECS
                     PEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLMTWENTFIPG
                     LEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKNNKKRLKLC"
     gene            9580..10803
                     /locus_tag="ACF3MF_000008"
     CDS             9580..10803
                     /locus_tag="ACF3MF_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFE3926048.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(10889..12823)
                     /locus_tag="ACF3MF_000009"
     CDS             complement(10889..12823)
                     /locus_tag="ACF3MF_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFE3926049.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            13049..13705
                     /locus_tag="ACF3MF_000010"
     CDS             13049..13705
                     /locus_tag="ACF3MF_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HFE3926050.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     SHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            complement(13779..14132)
                     /locus_tag="ACF3MF_000011"
     CDS             complement(13779..14132)
                     /locus_tag="ACF3MF_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HFE3926051.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            14324..15253
                     /locus_tag="ACF3MF_000012"
     CDS             14324..15253
                     /locus_tag="ACF3MF_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HFE3926052.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            15264..16100
                     /locus_tag="ACF3MF_000013"
     CDS             15264..16100
                     /locus_tag="ACF3MF_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HFE3926053.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            16348..17124
                     /locus_tag="ACF3MF_000014"
     CDS             16348..17124
                     /locus_tag="ACF3MF_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFE3926054.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            17300..18043
                     /locus_tag="ACF3MF_000015"
     CDS             17300..18043
                     /locus_tag="ACF3MF_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3926055.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            18036..19616
                     /locus_tag="ACF3MF_000016"
     CDS             18036..19616
                     /locus_tag="ACF3MF_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HFE3926056.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(19867..20346)
                     /locus_tag="ACF3MF_000017"
     CDS             complement(19867..20346)
                     /locus_tag="ACF3MF_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFE3926057.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(20362..21114)
                     /locus_tag="ACF3MF_000018"
     CDS             complement(20362..21114)
                     /locus_tag="ACF3MF_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFE3926058.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            21231..21301
                     /locus_tag="ACF3MF_000019"
     tRNA            21231..21301
                     /locus_tag="ACF3MF_000019"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21263..21265,aa:Gly,seq:ccc)
     gene            21662..22387
                     /locus_tag="ACF3MF_000020"
     CDS             21662..22387
                     /locus_tag="ACF3MF_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HFE3926059.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            22642..22908
                     /locus_tag="ACF3MF_000021"
     CDS             22642..22908
                     /locus_tag="ACF3MF_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HFE3926060.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            22905..23336
                     /gene="ruvX"
                     /locus_tag="ACF3MF_000022"
     CDS             22905..23336
                     /gene="ruvX"
                     /locus_tag="ACF3MF_000022"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HFE3926061.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            23361..23666
                     /locus_tag="ACF3MF_000023"
     CDS             23361..23666
                     /locus_tag="ACF3MF_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HFE3926062.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(23747..24892)
                     /locus_tag="ACF3MF_000024"
     CDS             complement(23747..24892)
                     /locus_tag="ACF3MF_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFE3926063.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(24953..25600)
                     /locus_tag="ACF3MF_000025"
     CDS             complement(24953..25600)
                     /locus_tag="ACF3MF_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFE3926064.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            25794..26087
                     /locus_tag="ACF3MF_000026"
     CDS             25794..26087
                     /locus_tag="ACF3MF_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926065.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            26131..26442
                     /locus_tag="ACF3MF_000027"
     CDS             26131..26442
                     /locus_tag="ACF3MF_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926066.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            26439..27063
                     /locus_tag="ACF3MF_000028"
                     /pseudo
     CDS             26439..27063
                     /locus_tag="ACF3MF_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            27204..27362
                     /locus_tag="ACF3MF_000029"
     CDS             27204..27362
                     /locus_tag="ACF3MF_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926067.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            27363..27725
                     /locus_tag="ACF3MF_000030"
     CDS             27363..27725
                     /locus_tag="ACF3MF_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926068.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            27762..28610
                     /locus_tag="ACF3MF_000031"
     CDS             27762..28610
                     /locus_tag="ACF3MF_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HFE3926069.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            28600..30075
                     /locus_tag="ACF3MF_000032"
     CDS             28600..30075
                     /locus_tag="ACF3MF_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VapE domain-containing protein"
                     /protein_id="HFE3926070.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            30341..30748
                     /locus_tag="ACF3MF_000033"
     CDS             30341..30748
                     /locus_tag="ACF3MF_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HFE3926071.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            30751..30966
                     /locus_tag="ACF3MF_000034"
     CDS             30751..30966
                     /locus_tag="ACF3MF_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926072.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            30970..31350
                     /locus_tag="ACF3MF_000035"
     CDS             30970..31350
                     /locus_tag="ACF3MF_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HFE3926073.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            31484..31639
                     /locus_tag="ACF3MF_000036"
     CDS             31484..31639
                     /locus_tag="ACF3MF_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HFE3926074.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            31708..32181
                     /locus_tag="ACF3MF_000037"
     CDS             31708..32181
                     /locus_tag="ACF3MF_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HFE3926075.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            32178..33872
                     /locus_tag="ACF3MF_000038"
     CDS             32178..33872
                     /locus_tag="ACF3MF_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HFE3926076.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            33838..34023
                     /locus_tag="ACF3MF_000039"
     CDS             33838..34023
                     /locus_tag="ACF3MF_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926077.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            34027..35202
                     /locus_tag="ACF3MF_000040"
     CDS             34027..35202
                     /locus_tag="ACF3MF_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFE3926078.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            35195..36718
                     /locus_tag="ACF3MF_000041"
     CDS             35195..36718
                     /locus_tag="ACF3MF_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFE3926079.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            36774..37058
                     /locus_tag="ACF3MF_000042"
     CDS             36774..37058
                     /locus_tag="ACF3MF_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail connector protein"
                     /protein_id="HFE3926080.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            37045..37380
                     /locus_tag="ACF3MF_000043"
     CDS             37045..37380
                     /locus_tag="ACF3MF_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HFE3926081.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            37675..38301
                     /locus_tag="ACF3MF_000044"
     CDS             37675..38301
                     /locus_tag="ACF3MF_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926082.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            39043..39879
                     /locus_tag="ACF3MF_000045"
     CDS             39043..39879
                     /locus_tag="ACF3MF_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HFE3926083.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLVNCYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            39944..40378
                     /locus_tag="ACF3MF_000046"
     CDS             39944..40378
                     /locus_tag="ACF3MF_000046"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFE3926084.1"
                     /translation="MLREMRLEDAEALREINADQLGYDIPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKYAEKRGIGKALMTGVEEE
                     AKKRGITTIRLNSAEYRVEAHQFYEHIGYHSDKMQKRFLKIL"
     gene            complement(40446..41768)
                     /locus_tag="ACF3MF_000047"
     CDS             complement(40446..41768)
                     /locus_tag="ACF3MF_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HFE3926085.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFWDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRTVKPSIPQLGVGLMVSL
                     TFFILGQIGNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(41922..43562)
                     /locus_tag="ACF3MF_000048"
     CDS             complement(41922..43562)
                     /locus_tag="ACF3MF_000048"
                     /EC_number="4.1.1.101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043883 - malolactic enzyme activity
                     [Evidence IEA];
                     GO_process: GO:0043464 - malolactic fermentation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malolactic enzyme"
                     /protein_id="HFE3926086.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAAAILEKYEDQITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQIILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     EGLTPGQIPFARKRSDFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQNLNREEITDIKEAVESAKWVPEYKSLED"
     gene            43892..44362
                     /locus_tag="ACF3MF_000049"
     CDS             43892..44362
                     /locus_tag="ACF3MF_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HFE3926087.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLDSNQAIISELTV
                     GGLVDSLALAEGFTGEDIYEMFSEVRQLKKGEKCIEVHHESPNVRFKRGDNEMIFKNH
                     VSDHTELYEIVNQILSGIFELGPYEFKEENGNPKLNEEWQETIETQRNNPHLFQ"
     gene            44991..46094
                     /locus_tag="ACF3MF_000050"
     CDS             44991..46094
                     /locus_tag="ACF3MF_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HFE3926088.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHRLIIPHVLRDVELPDTTTHFDEEMLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDNGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRAPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            46378..47058
                     /locus_tag="ACF3MF_000051"
     CDS             46378..47058
                     /locus_tag="ACF3MF_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFE3926089.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGSLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            47148..48182
                     /locus_tag="ACF3MF_000052"
     CDS             47148..48182
                     /locus_tag="ACF3MF_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HFE3926090.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTIPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNEFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            48196..48531
                     /locus_tag="ACF3MF_000053"
                     /pseudo
     CDS             48196..48531
                     /locus_tag="ACF3MF_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            48515..50995
                     /locus_tag="ACF3MF_000054"
     CDS             48515..50995
                     /locus_tag="ACF3MF_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926091.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLADIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISTSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSVQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYEAKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            51051..52610
                     /locus_tag="ACF3MF_000055"
     CDS             51051..52610
                     /locus_tag="ACF3MF_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3926092.1"
                     /translation="MRRKLLLLKSEMLGGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     ISVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQICYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFTITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            52607..53971
                     /locus_tag="ACF3MF_000056"
     CDS             52607..53971
                     /locus_tag="ACF3MF_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding oxidoreductase"
                     /protein_id="HFE3926093.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQAIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEHTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            54142..55212
                     /locus_tag="ACF3MF_000057"
     CDS             54142..55212
                     /locus_tag="ACF3MF_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFE3926094.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAVGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            55227..55895
                     /locus_tag="ACF3MF_000058"
     CDS             55227..55895
                     /locus_tag="ACF3MF_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3926095.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEAKELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            55915..56493
                     /locus_tag="ACF3MF_000059"
     CDS             55915..56493
                     /locus_tag="ACF3MF_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFE3926096.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            56896..57807
                     /locus_tag="ACF3MF_000060"
     CDS             56896..57807
                     /locus_tag="ACF3MF_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFE3926097.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(58063..58980)
                     /gene="rnhC"
                     /locus_tag="ACF3MF_000061"
     CDS             complement(58063..58980)
                     /gene="rnhC"
                     /locus_tag="ACF3MF_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HFE3926098.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            59182..59619
                     /gene="zapA"
                     /locus_tag="ACF3MF_000062"
     CDS             59182..59619
                     /gene="zapA"
                     /locus_tag="ACF3MF_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HFE3926099.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            59677..60225
                     /locus_tag="ACF3MF_000063"
     CDS             59677..60225
                     /locus_tag="ACF3MF_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HFE3926100.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            60340..62700
                     /locus_tag="ACF3MF_000064"
     CDS             60340..62700
                     /locus_tag="ACF3MF_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HFE3926101.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            62787..63101
                     /gene="trxA"
                     /locus_tag="ACF3MF_000065"
     CDS             62787..63101
                     /gene="trxA"
                     /locus_tag="ACF3MF_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HFE3926102.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            63283..65061
                     /gene="uvrC"
                     /locus_tag="ACF3MF_000066"
     CDS             63283..65061
                     /gene="uvrC"
                     /locus_tag="ACF3MF_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HFE3926103.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKKFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELANKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGIDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            65206..66105
                     /locus_tag="ACF3MF_000067"
     CDS             65206..66105
                     /locus_tag="ACF3MF_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3926104.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            66098..67360
                     /locus_tag="ACF3MF_000068"
     CDS             66098..67360
                     /locus_tag="ACF3MF_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFE3926105.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            67523..69421
                     /locus_tag="ACF3MF_000069"
     CDS             67523..69421
                     /locus_tag="ACF3MF_000069"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042132 - fructose 1,6-bisphosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HFE3926106.1"
                     /translation="MDRYLDLLSEKFPTTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETEISQFTIFTAYPEYVLTTDWYKKQDKS
                     QLIHRLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFTP
                     KNRKDLSEREQEELEKIHQALSILQFKSEHQLLNRRPEFKMDDRKLLEKINYEESTIV
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTANEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDAKEEGSAIINGHTPVKVKKGESPIKANGKAFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRNTTKGMELQQQITQLQR
                     LLDYRKDD"
     gene            complement(69720..70439)
                     /locus_tag="ACF3MF_000070"
     CDS             complement(69720..70439)
                     /locus_tag="ACF3MF_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HFE3926107.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIEKIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFATHEVKIVSD
                     SLLSDLLPDSYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDNMHKILGVQWHP
                     ELSHRVDSSEQRLFDFFVNEF"
     misc_feature    70629..70676
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF03071"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="sodium ion sensor (DUF1646 type); this
                     cis-regulatory element may regulate processes involved in
                     with the transportation of sodium ions; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF03071"
     gene            70776..71108
                     /locus_tag="ACF3MF_000071"
     CDS             70776..71108
                     /locus_tag="ACF3MF_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926108.1"
                     /translation="MKQVLEALEQIRKAEEENEKRARTLRQQLKTYAEEKEQELEIIQ
                     TNSRQQLKQLVEEKEQFEKQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            71095..73098
                     /locus_tag="ACF3MF_000072"
     CDS             71095..73098
                     /locus_tag="ACF3MF_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HFE3926109.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFMNKLEEVLDLKEKWEQLTEKRDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAAIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKVKERFIHATYLIVLQGWVDAEEKQNLMHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLIEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLFVLPRGMKRFVKFFEILSVPSIIWGLIYSSFFGQALPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALIGVMLIKNTAFVYLGAGLSIIAALCILIVPIIQSPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            73117..73587
                     /locus_tag="ACF3MF_000073"
     CDS             73117..73587
                     /locus_tag="ACF3MF_000073"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HFE3926110.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            73608..74192
                     /locus_tag="ACF3MF_000074"
     CDS             73608..74192
                     /locus_tag="ACF3MF_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit E"
                     /protein_id="HFE3926111.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQIETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAIAEMENWDESEQ
                     IQFIKNSLYSLPLTGKVTFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            74207..75193
                     /locus_tag="ACF3MF_000075"
     CDS             74207..75193
                     /locus_tag="ACF3MF_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046961 - proton-transporting ATPase
                     activity, rotational mechanism [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HFE3926112.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNLDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFEPETIRKRVRQVYDA"
     gene            75183..75494
                     /locus_tag="ACF3MF_000076"
     CDS             75183..75494
                     /locus_tag="ACF3MF_000076"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HFE3926113.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            75516..77297
                     /locus_tag="ACF3MF_000077"
     CDS             75516..77297
                     /locus_tag="ACF3MF_000077"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HFE3926114.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            77290..78666
                     /locus_tag="ACF3MF_000078"
     CDS             77290..78666
                     /locus_tag="ACF3MF_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HFE3926115.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            78673..79308
                     /locus_tag="ACF3MF_000079"
     CDS             78673..79308
                     /locus_tag="ACF3MF_000079"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HFE3926116.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            79338..80693
                     /locus_tag="ACF3MF_000080"
     CDS             79338..80693
                     /locus_tag="ACF3MF_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HFE3926117.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(80885..82279)
                     /locus_tag="ACF3MF_000081"
     CDS             complement(80885..82279)
                     /locus_tag="ACF3MF_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFE3926118.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            82371..83342
                     /locus_tag="ACF3MF_000082"
     CDS             82371..83342
                     /locus_tag="ACF3MF_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HFE3926119.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            83339..84121
                     /locus_tag="ACF3MF_000083"
     CDS             83339..84121
                     /locus_tag="ACF3MF_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HFE3926120.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(84290..84661)
                     /locus_tag="ACF3MF_000084"
     CDS             complement(84290..84661)
                     /locus_tag="ACF3MF_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFE3926121.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            84795..85238
                     /locus_tag="ACF3MF_000085"
     CDS             84795..85238
                     /locus_tag="ACF3MF_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFE3926122.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(85281..86090)
                     /gene="yidA"
                     /locus_tag="ACF3MF_000086"
     CDS             complement(85281..86090)
                     /gene="yidA"
                     /locus_tag="ACF3MF_000086"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HFE3926123.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(86109..87476)
                     /locus_tag="ACF3MF_000087"
     CDS             complement(86109..87476)
                     /locus_tag="ACF3MF_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFE3926124.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(87460..88290)
                     /locus_tag="ACF3MF_000088"
     CDS             complement(87460..88290)
                     /locus_tag="ACF3MF_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HFE3926125.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            88453..88890
                     /locus_tag="ACF3MF_000089"
     CDS             88453..88890
                     /locus_tag="ACF3MF_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HFE3926126.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTGGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            88966..89586
                     /gene="rpoE"
                     /locus_tag="ACF3MF_000090"
     CDS             88966..89586
                     /gene="rpoE"
                     /locus_tag="ACF3MF_000090"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HFE3926127.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            89775..90281
                     /locus_tag="ACF3MF_000091"
     CDS             89775..90281
                     /locus_tag="ACF3MF_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HFE3926128.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            90298..91197
                     /locus_tag="ACF3MF_000092"
     CDS             90298..91197
                     /locus_tag="ACF3MF_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsiV family protein"
                     /protein_id="HFE3926129.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            91284..92168
                     /locus_tag="ACF3MF_000093"
     CDS             91284..92168
                     /locus_tag="ACF3MF_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFE3926130.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(92360..92431)
                     /locus_tag="ACF3MF_000094"
     tRNA            complement(92360..92431)
                     /locus_tag="ACF3MF_000094"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(92396..92398),aa:Arg,seq:ccg)
     gene            92491..93825
                     /gene="rpoN"
                     /locus_tag="ACF3MF_000095"
     CDS             92491..93825
                     /gene="rpoN"
                     /locus_tag="ACF3MF_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HFE3926131.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            93974..95065
                     /locus_tag="ACF3MF_000096"
     CDS             93974..95065
                     /locus_tag="ACF3MF_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HFE3926132.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            95106..96107
                     /gene="gap"
                     /locus_tag="ACF3MF_000097"
     CDS             95106..96107
                     /gene="gap"
                     /locus_tag="ACF3MF_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFE3926133.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            96217..97407
                     /gene="pgk"
                     /locus_tag="ACF3MF_000098"
     CDS             96217..97407
                     /gene="pgk"
                     /locus_tag="ACF3MF_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HFE3926134.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            97511..98266
                     /gene="tpiA"
                     /locus_tag="ACF3MF_000099"
     CDS             97511..98266
                     /gene="tpiA"
                     /locus_tag="ACF3MF_000099"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HFE3926135.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            98382..99680
                     /gene="eno"
                     /locus_tag="ACF3MF_000100"
     CDS             98382..99680
                     /gene="eno"
                     /locus_tag="ACF3MF_000100"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000015 - phosphopyruvate hydratase
                     complex [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HFE3926136.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            100080..101219
                     /locus_tag="ACF3MF_000101"
     CDS             100080..101219
                     /locus_tag="ACF3MF_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HFE3926137.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            complement(101286..101861)
                     /locus_tag="ACF3MF_000102"
     CDS             complement(101286..101861)
                     /locus_tag="ACF3MF_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytS/YhcK type 5TM receptor domain-containing
                     protein"
                     /protein_id="HFE3926138.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(101866..102840)
                     /locus_tag="ACF3MF_000103"
     CDS             complement(101866..102840)
                     /locus_tag="ACF3MF_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HFE3926139.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIAFALKVNPNIGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEGAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(102864..102908)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            103123..104091
                     /locus_tag="ACF3MF_000104"
     CDS             103123..104091
                     /locus_tag="ACF3MF_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFE3926140.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMN"
     gene            104204..104482
                     /locus_tag="ACF3MF_000105"
     CDS             104204..104482
                     /locus_tag="ACF3MF_000105"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFE3926141.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            104600..104836
                     /gene="secG"
                     /locus_tag="ACF3MF_000106"
     CDS             104600..104836
                     /gene="secG"
                     /locus_tag="ACF3MF_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HFE3926142.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            104939..105694
                     /locus_tag="ACF3MF_000107"
     CDS             104939..105694
                     /locus_tag="ACF3MF_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFE3926143.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLRW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            105697..108054
                     /gene="rnr"
                     /locus_tag="ACF3MF_000108"
     CDS             105697..108054
                     /gene="rnr"
                     /locus_tag="ACF3MF_000108"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HFE3926144.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWATELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKTRNGKSGKRE
                     GKQAGKRPERNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            108076..108540
                     /gene="smpB"
                     /locus_tag="ACF3MF_000109"
     CDS             108076..108540
                     /gene="smpB"
                     /locus_tag="ACF3MF_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HFE3926145.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIIRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            108842..109561
                     /gene="atpB"
                     /locus_tag="ACF3MF_000110"
     CDS             108842..109561
                     /gene="atpB"
                     /locus_tag="ACF3MF_000110"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HFE3926146.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMVISLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            109614..109829
                     /gene="atpE"
                     /locus_tag="ACF3MF_000111"
     CDS             109614..109829
                     /gene="atpE"
                     /locus_tag="ACF3MF_000111"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HFE3926147.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVVALILVFGV"
     gene            109920..110444
                     /gene="atpF"
                     /locus_tag="ACF3MF_000112"
     CDS             109920..110444
                     /gene="atpF"
                     /locus_tag="ACF3MF_000112"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HFE3926148.1"
                     /translation="MLNQLAIAEVGNAMLGNVIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            110431..110973
                     /locus_tag="ACF3MF_000113"
     CDS             110431..110973
                     /locus_tag="ACF3MF_000113"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HFE3926149.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNKAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYAYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMNYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLENMRNQLNR"
     gene            110996..112552
                     /gene="atpA"
                     /locus_tag="ACF3MF_000114"
     CDS             110996..112552
                     /gene="atpA"
                     /locus_tag="ACF3MF_000114"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HFE3926150.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            112566..113468
                     /locus_tag="ACF3MF_000115"
     CDS             112566..113468
                     /locus_tag="ACF3MF_000115"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HFE3926151.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            113491..114897
                     /gene="atpD"
                     /locus_tag="ACF3MF_000116"
     CDS             113491..114897
                     /gene="atpD"
                     /locus_tag="ACF3MF_000116"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HFE3926152.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            114911..115333
                     /locus_tag="ACF3MF_000117"
     CDS             114911..115333
                     /locus_tag="ACF3MF_000117"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HFE3926153.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            115802..116032
                     /locus_tag="ACF3MF_000118"
     CDS             115802..116032
                     /locus_tag="ACF3MF_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HFE3926154.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            116129..117430
                     /gene="murA"
                     /locus_tag="ACF3MF_000119"
     CDS             116129..117430
                     /gene="murA"
                     /locus_tag="ACF3MF_000119"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFE3926155.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            117443..117619
                     /locus_tag="ACF3MF_000120"
     CDS             117443..117619
                     /locus_tag="ACF3MF_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFE3926156.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            117754..118050
                     /gene="yidD"
                     /locus_tag="ACF3MF_000121"
     CDS             117754..118050
                     /gene="yidD"
                     /locus_tag="ACF3MF_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HFE3926157.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFQLTRNKKDKKEPDYKKVVKNTSSTER"
     gene            118234..118701
                     /locus_tag="ACF3MF_000122"
     CDS             118234..118701
                     /locus_tag="ACF3MF_000122"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFE3926158.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVAPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            118786..119670
                     /locus_tag="ACF3MF_000123"
     CDS             118786..119670
                     /locus_tag="ACF3MF_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFE3926159.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNSYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            119784..120020
                     /locus_tag="ACF3MF_000124"
     CDS             119784..120020
                     /locus_tag="ACF3MF_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HFE3926160.1"
                     /translation="MMSKKNKDVEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            120108..120188
                     /locus_tag="ACF3MF_000125"
     tRNA            120108..120188
                     /locus_tag="ACF3MF_000125"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:120142..120144,aa:Tyr,seq:gta)
     gene            120195..120266
                     /locus_tag="ACF3MF_000126"
     tRNA            120195..120266
                     /locus_tag="ACF3MF_000126"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:120227..120229,aa:Gln,seq:ttg)
BASE COUNT        39937 a        20618 c        25018 g        34768 t
ORIGIN      
        1 tgttaaataa ataggaacaa aaaaattaaa ttatttaata cacacattag ggatcattca
       61 ttgaaggatt agaagacaac gaggatggcg aaaaatatga ttacaataga aaagtcgttc
      121 taaaccaatc agttcctagt atcacacaac gcaagccagt cgatttggtg agattagagg
      181 agtgaaagca aactttatta tataagaaaa aatattcgaa agggatgcta gtttaggtac
      241 tagtgctgat agattaatat gatgcctcgt aatattaggc gtagttactc tagagacatc
      301 actatggact atgatttgtc tcagagtcac aacatgtttt tttatgaaaa gaaacagcta
      361 aaataattaa attgcgcaat gtttaaactt tcttaaacta taacctaata aatgtgaaga
      421 aataatgcac aatttcttca catttatctt ctattctata tacataccaa ccaacaaccc
      481 tatatacttt ttcattttta ctcctcaagt aaaaataact cctagaccgc ggctacccac
      541 cgcggtcgtt tttttattct tcaatcaaaa tcgctttgat acccaaacct gccaagattc
      601 gggcagaagt ataagtattc aatcctcttc tgaaagtaat gtaaactttt ttatcttttg
      661 ggatttcatt gattcgatct cgtaactcat tcattggaat attttttgtt gccgagatac
      721 tgccagaagg tgctttatta ggttcacgta tatctaaaaa gaacgcttct ttcaaatcgt
      781 tttcgggtat atcacttgct ttgatcgttt ctacgatatt cgtcatttga ttgattgcga
      841 cataaccagc tatattcaac gggtcacggg tagtagaata cggtggagag taaggcaact
      901 ccaaatcagg caaatcaaag actgtcaagt ttccggtgat tgctacagaa agttctccca
      961 tccgtttatc gacacctttt tctccaaatg cttgtccacc taaaatacga ccgctatctg
     1021 catcaaaaat cagctttaga tttaatcttg tagcttctgg atagaaatag gcatggtcaa
     1081 agggagtgat aaaaacagtt ttataatttg ttatgcctga tgcttttaat tcatgttctg
     1141 tcattcccgc ataacttgct gtatgatcaa agatttttgc gacacctgca ccaatatatc
     1201 cgcgatagcg cataggcgta ccatttaaaa tatctgccag catatgtcct tgacgattgg
     1261 ccgcactgga aagcatactt tggatcggct gaccagtcac tacactagtc gtttcgataa
     1321 tatcgccaat cgcatagatg tccggcagat tggtttgtaa ctggtcatca acaatgatct
     1381 gacctgtatc tgataattgt atgccggttg ctttcaccac ttcattcttc ggagaaacac
     1441 caacagcaaa aattagcata tcagcagaaa ggacggagcc atctgataat actatttctc
     1501 gacctttatc acggatctca gtaactcttg tttctaaatg aacggctaat ccttctttca
     1561 gcaatttgtc ataaactaaa ttagcaattt ctggatcata agggaaagcg acttgtggca
     1621 attgatcgat taaagtcacg tctaagccgc gatgcttgaa attctcagct aattccagac
     1681 ccataacacc tgcaccaaga atgacgacat gttgtggatt tttttcttca aggaacgatt
     1741 tgattcgatc cgcatccgtc acactacgga ggacaaagcc gttttctgct tcaaaaactc
     1801 cgggaatatc cggataatct ggtctagcac cagaagagat gatcaactta tcgtaatctg
     1861 tttttatttc ttcatttgtg gataggtctt taactgttaa tcgcttagta gaaggatcga
     1921 ttgctgttac ttcgtgttta gtaaagacat cgatgttgtt ttttgttttc aatatttctg
     1981 gtgtacgttc gatcagcgag tcacggtcag tgatcacacc tcctaaataa taaggcaaag
     2041 cacaacttgc ataagaaata ttttctccgc gttcatagat aatgatttcg tgcgcttcat
     2101 tcaatcgacg gaaacgagtg gcaaatgaag gaccgccagc tacaccgcca atgacaacaa
     2161 ctttcataaa aacatctcct tttctacgtt gatcgtacta tgttatggta aaaaacagca
     2221 aataattgtg ccggaaaatt attgtttatt ttgaatagac agaaaatata gagaaataat
     2281 ttgtggataa aacctaaaaa tttttttcta ttttaaggat agataatact ttgaagggga
     2341 taaccctgta tattttttaa aagctgaaga aaaatgatgg atcgaatgaa atcctaatat
     2401 atctgcaatt tctgtatagg ttaattcatt ttctagcacg agacgttttg ctttttccat
     2461 ttttagttct ttaaaatagc taataacact ttttccattc acttttctaa aatgtttttt
     2521 taagctggct ggactgataa aaaaaatttg ggctaattgt tcaagcaaaa atttttctga
     2581 aagatgttct tctaaatatc gtatgattgg atcaactaat tcatctgaat aaagaatatg
     2641 ctttttttta ggaatgactt tctcatttga aggtattgtc aataaagcaa gttcctgttg
     2701 ataatgcctt ggtaaggaag acaattgaat tttttgcaga caataagtaa ctaataagga
     2761 aagcaaatga atgctcatct gttggcatag tatgaaaaaa gaattgattt cctgatcata
     2821 ggaaatagct ggcttactat gttttagata atcaattttg aactgttcat ttttcagaaa
     2881 agtaatgata gatgttattt cttgatctat agaaaaagat tgtcccgtaa tatgtgctaa
     2941 taattgctca tcaaaataaa actggataat gataaaagtt tgtgtttcct tttgagtaga
     3001 aaagatttgg acttcttgct gtttatcaat gaataaaagg gaaggattat ctagttctat
     3061 agatttatgt gcaaattcag catataaatt agcgctttca tttattagta gtcgaaaata
     3121 gggagcagca gataaatgaa gatgggtatc tatggaatag gttagtgttt ttttgacaag
     3181 attggaggat tggttgtttg ttaacaaaag aaccactttc ctttctcttt ttatataaaa
     3241 agctttctat ttataattaa tgactattat aacaaaaatg aaaagccaaa acgacaagta
     3301 aaatattttt ttatataaat atttgtgtta ctaattccgt taatatacat aagtgaaagc
     3361 gttttatata agaacttgaa aagaaagaag ggatagacat gaaaaaaaga tacaaattgg
     3421 tgatagcttt gctaaacatt accctattat tcagcttaag tgcatgtgga aaaactaacg
     3481 aagaagtaac agcaaacatc gcagatccaa tgataaaaaa agccactaca ttagaagtat
     3541 atgtcgcaaa cggcaaactg acaaactatg ttgaaaatgc tgcaaaaatc tataaccgca
     3601 aaactggagc aaatattgac ttaaaaattg tgaatgtagc ttcgggaaca gcaacagtac
     3661 aaatgatcac cccaaaattg gtaacacacg aagatatgcc ggatattatc tccatggcag
     3721 acacttcagc agcaggtgtg ctggaaaaat ttcaagatgc tttttatagt gctgatgaat
     3781 atggatttta tgacaaatat ggcgatcagt tttatgatca aaaattgaat attttgcgtc
     3841 aacaaacgag taatgaaacg attattcctt gggctagtga ttttacccca gcactttgtt
     3901 attatcaacc aaaaaaattt gctgaaatag gtgtagattt tgaagaaatc agttcttggg
     3961 aagaatatat ccaggtggca aaagcattaa aagaaaaaac tggtagtttt ggaattgcct
     4021 tgccagaatc tggggaccaa gaattgttta tcaacatgct agcccagcag aatcaatctt
     4081 tgcttgatga agaaggaaat atccgtctga atactaaaga agcgaaacat gctgcaaagt
     4141 taatcaaaga aatgatcgac tcagatattg tacatttcta cggtgcacaa gatgctgaga
     4201 aagcatttca agaatctgca atgtttgttg ctggcggctg gtatgctacg aatatgtctt
     4261 tgaattttcc tgatgcatct gacaaatggc gcatggctcc actgattcct ttttcaaaag
     4321 aaaatccagg aaaaggtgca gtatcaggag gatcaagttt ttatgtccct aaagatgcca
     4381 aaaatccaca agtggcacaa caatttctta catttatgct gacagatgaa gaatgcttag
     4441 ccaacgcact ggagctgggc gtggctacat ctaactcatt ggcctatcaa acagaagcag
     4501 ctgagaaaaa gtttgactac taaggaggac aaaaatacta tgaactattg aataaaatca
     4561 atgaaaatac atcaaatact gttttaccag ccacttattc agatgctacg tcttatttga
     4621 ctaccgctgc atataactat tggcaaacag gtgattttga aaattcatat ctaaaagaag
     4681 cagaaaattt tgctcataag tacggcgtaa aattaactgg tgattaaaaa atattaggag
     4741 gacttaacga tgatgcaatc ttcgttacca agcaagacaa taaagaacag caagaaaaaa
     4801 gcaacagata cgtctcataa aaaaagtgct tatggattgg tcacaccttt tgttattttc
     4861 tttattgtga cgattttgat tcccatcatt atctcgtttg cttttagttt tatgaaaatt
     4921 ggctactcat ttgaatttgt tggatttgac aattatctag ctatcttccg agatccattg
     4981 tttattaaat cttacacgaa tgttttgatt atcatggcag gatcaattcc aataacgatg
     5041 ctattagcta tttactttgc tgttttattg aattcagcac agttaaaagg aaaaggattt
     5101 tttagaactg tctattatat tccaaccatt acatcaacgg tggctgtagc ttccgtattc
     5161 atgacttttt tcaatccgac tgggttattc aatggatttt tgaatgcgct aggaattaac
     5221 ggtgtacagt ggttaacaaa tcctttttgg atacgaatat caatgatcat cacgatgatt
     5281 tggcttagtg taggatataa cactatttta tttttagctg gtcttcaagg gatttctaaa
     5341 gagatatacg aaagtgctga aatagatgga gcatcgaaat ttcggcaatt ctttttatta
     5401 acgatcccca tgctaaagcc aatcatttta atggccacag ttttagccac tatcaatggc
     5461 ttgggtaatt tcaatatccc aaatatattc tttgggactt ccaatggacc agaaaattca
     5521 gctttggtcg taggagtcaa tttatataaa acaagttttg aaatggttga ttttggaaaa
     5581 gcctctgcta ttgcctggac gatggtgttt gtatctgtta tattatcggc tattcaattt
     5641 aaattcggag gtgataaaaa tgactaaaca aaagatacaa agcagaattt ttacgtacgt
     5701 cattattgtg tttggtgcct taatattttt gatgccatat ttatatatga ttgtagcttc
     5761 aacgcaaagt aatcaagaaa ttttaagtgg cggaatcaat ttcaagtttg gggatatgct
     5821 attaaaaaac tggcaagcca tcatggcgag atataattat cccttgatta tttggaattc
     5881 gattgttatt gctgtaatca gtacagtttt agctacagcc agttctacaa tggcgggtta
     5941 tgcattagca aagtatcgtt ttatggggaa taaactgttg ttcaatacag ttatgctatc
     6001 taggatggtg ccttttttta ccacattgat tcctttattt tacattatga gtcgtttagg
     6061 attatcgaat acttatgcag gtgtgatcat cccttcgatt gccagtacaa cttcagtgtt
     6121 tatgatgcga caatatagca gtcaatttcc tacagcactg atggaggctg ccagaatcga
     6181 tggtgccaat gagtgggtga tttttacgaa aatcgctgta ccgattttat cacctacgat
     6241 tattactagt ggtttactta tctttatggg aagttggaat caatatctat ttccattagt
     6301 catgctttca gataaagata aatatacggt tcccttaatt atcaaaaata tgacggtttc
     6361 tagtacaggt gagccaatta attatggcgc aattatgcta attttagcaa cttcagtgat
     6421 cccaatggtc ttgatttatg tgtgggcgca gtctaaattt aaggagaatg acattggagc
     6481 tgcaaataag taaaaaaaat aacgaatgtt aaccatctag ttcgttctag gagcaactcc
     6541 acattcataa aaattaaaag aatggcggga tatccatgaa tgaacagacg aaggaatggt
     6601 caagaaaaat tttgaatgta gcttctgaaa agatagatgc ggaattagac agaatgggga
     6661 ataaaattcc atatatttct tacaacggaa aatatacaga cgtaataaag gacagaggaa
     6721 tcgattggtg gaccaatggt ttttggagtg gtattttatg gcagctcttt cacaagacaa
     6781 aacgagaaaa gttcaaagag gcagcaatac aacaagaaca attattagaa tctgccctgt
     6841 accatttttc agacgttcat catgatgtag gttttttatt cttaccatcg gctattgcac
     6901 attatcaaca gtctcaaaac aaacatagtc gacaactagg gttacatgca gctacggtac
     6961 ttgctggacg ctataatatt tcagggaact atttagtagc atggaatgac cataaacctg
     7021 gttggatgat tattgatagt atgatgaatt taccattact gtattgggct tcgagggaaa
     7081 ctggtgatcc gaggttctct aaaattgctc ggcagcatgc agatacaaca gctaagtatc
     7141 tagtgaggaa agatggatca accgggcata tcgcagaatt tgatgcagaa tcagggaaat
     7201 atattcggtt acttggcggg caaggataca atgagaattc ttgttggagc agaggaaatg
     7261 catgggcttt atatggattc gcgttaagtt atcgttacac aaaaaatccg tactatctag
     7321 ctatagcaga aaagatagca gtaaatttta ttcagaaaat cgaaaaaact ggttatattc
     7381 ctctcattga ttttgctgta aaagattcga atattgatac cagtgctgga gtatgcgctg
     7441 catgcggtct tctggaatta gcaggatatg tttcctctgt acgatcaaaa atgtatcatg
     7501 aagctgctat caatatactc caaaagacag aaaagcacta tgcaaattgg aatatggatg
     7561 aagatgggat cattggaggc ggagcagaag cataccatag agaactgact tataatgtgc
     7621 cactgatcta ttctgattat ttttttattg aaggcttact tcgattagaa cagtcggaat
     7681 tagctatttg gtagtaaaaa gaggagaaaa tacaatgaaa catccagtac cactattaag
     7741 gaccagacag gattactttg acttatttaa aaagataaat caaccactcc agccgtttta
     7801 tcgagcaagt ggcgcacaaa ttgattatat acatcaaggg gtaggatatg gaaataaaat
     7861 tgcaggaatg gaaggattct ctcgggtttt atggggagcg gggcccgcaa ttgaccaatt
     7921 agatgaacga tggttgaaat taattctatc aggaataaaa gctggaacag atccttccca
     7981 tcccgattat tggggagaaa tacatgaaag agaccagcgt atggtagaaa tgcccgcaat
     8041 gttattagcg ttatatcatc atgaacaatt attatggaaa aaattagata caggagaaaa
     8101 aagccagatt attcattggt tctcgcaaat ttttgaatat gaatgtgcag atggtaattg
     8161 gcaatttttt aagataattg tcggaacaat tatccaaaaa tttggttatc cagttaaaga
     8221 atcagcactg aaagaagcat ttgataatat agaaaattgt tatcttcaaa atggctggta
     8281 tcgagacagt tcaagaggtc gccaagatta ttataatcct tttgcatttc attattatgg
     8341 tttgatttat agcgtactag aaccagaaaa gcccattagc cagatatata agaaccgagc
     8401 tattgatttt tctagagact atattcattt ttttgcggaa gatggtgcaa atgtgccttt
     8461 tggtcgaagc atgatttatc gttttgcagt ttcaagcttt tggtcagcta tgttgtgggc
     8521 cgatcttttg ccttttaaat taggtgaaat caaggggtta gtcaatcgga atataagatg
     8581 gtggatgcaa aaagaaatat ttgatgaaaa aggtatcctg aatattggtt atacctaccc
     8641 tcaattgaca ttgactgaac cctataatag tacgttatct ccattatggc tgaataagat
     8701 ttttttattg ttggcgctac ctgaagacca tgagtattgg acggctaaag aaatgcctat
     8761 gcctattcgt gaaggaacta aacttctttc agaagccaat ttgctcatac aacatgataa
     8821 tggacataca ttttttttga atgcgggaca attagggcca aatttccata cattgaccaa
     8881 tgaaaaatat ttaaaatttg cttattctag tcaatttggt ttttcgatac cgcgagcgaa
     8941 tcaattgaaa gcagaaatgg caatggattc aatgctaggg attcagcgag cggacacata
     9001 tatcacgacc agttttaaga atgagagcat caaaacctat ggacagttca tcgttcgaaa
     9061 taatgtacga gacattgtat gtaagaaaga ggtacttgcc tctacatggg aacctacttt
     9121 acaggcaaaa atcagaactt ggcttattcc ttttgaaggc tggcagattc gcgtacacaa
     9181 agtagaatta gatacagaat atgttctata tgagacaggg tttgctattg aatgttctcc
     9241 tgagaaagaa ggaataatca tagaagaaga caaggaaaac tatagggtga gtgaagctgg
     9301 cttttcaggt attatctgtt taagtgacga tactattaaa cgaaaatcca cagctattat
     9361 gggtttgccc aatacaaact tgatgacatg ggaaaacact tttattcctg gattagaggg
     9421 tacatttgga aaaggaaccc attggctcgg aacaggagtg gttgctcatc aagatcggga
     9481 ttatagttta gaagtatgga acaatcgtcc caaaattgat tttgatggga caaccgggct
     9541 aactatccaa aataaaaaca ataaaaaaag actaaaatta tgctaaaggc tggtggggaa
     9601 atgcttgata aagtgatgtt tgaagagata atacatccag aaaaatggat aaatgaatgt
     9661 tataaagaat taatggaaaa agaatggaat aatgagatcg agcgttgtcg cagacacacg
     9721 gagaggttaa tcaaacgtat cagtaacagt cagtatcaat tcccaagcga gtgtcctata
     9781 aaaggacgtt atccattaag agacaatatt ggttggacag aaggattttg gacaggaatt
     9841 aattggttgt tatttgagaa gacgggtgat cctttatttc aacaaacagc tgaaaaagca
     9901 gatatagatt ttatccacag gattgactgt caaattatca ctaatcatca cgatcttggt
     9961 tttttgtatt ctttatcaac cgtagcagat tataaaataa cgggaaatcg aaaaatgaag
    10021 gaagcttcaa ttgatgctgc agaaacatta cttcagcgtt tttgggagaa ggcaggagtt
    10081 atacaagctt ggggagatcc tagtgatcct tcacaacaag gtagaatgat catggattgt
    10141 tgcatgaatc ttccattatt gtattgggcg agtgaagaaa ctggaaatca aaaatataaa
    10201 aaagctgctc aggctcatat tcaaaatgca gcagattatt tagtaagaga agatggttca
    10261 acttatcata cattttatat ggatgtcaaa gatggaaaac caagatatgg aagtacgcat
    10321 caaggttata gtgataattc ctgttgggct agaggccaag catgggggat ttacggtttt
    10381 gcattaagtt atcgttattt gaaagaacaa aaatattttg atttaagcaa aatattagcc
    10441 aattatttta tgaatcggtt gccagaagat accatttgtt attgggattt gatctttgat
    10501 gattctagca gagaagaaaa agatacatct agtatggtga tcatggtttg tggattatta
    10561 gaattaatag aatcaggtct attagacaaa acagaaaaga acttatacca gtctgctgtt
    10621 tggaaaatta tgcgacaatt gaaagaaaga tatgctacaa cggaagaaga agatggcttt
    10681 ttaacacagt ctgtttataa taagcccaaa aataatgggg taaatacacc ttgtatttgg
    10741 ggtgattact attatttaga agctttagtg agaatgacta gtaattggtc ttcttattgg
    10801 tgaaaaaggt aaatatggaa tttttgtttg ataaaataaa aaaagaaaaa ccaaaacagc
    10861 atgaatggtt tctgttttgg ttttttcgtt aattttcata ttcttctaat tccaagctta
    10921 gttcttccca ttccgtcaat tttgtttctt gatcttgtct agcagcttct aaatcttggt
    10981 tcagctcatt gagttttacg tgatcttcca ggttttctgg cgcgaccatt tcttgttcca
    11041 actgatcgat ccattcatcg atccgcgcca tttcttcttc aacctgagta atttttcgtt
    11101 gaaggctacg gataagcttt tgctgttctt tgctttggta ataatcagat ttgttcgtgg
    11161 gagcaggagc agattctggc tcatcttgtg ccaacaattc ggcgatttct tcttcttcct
    11221 gctttttctc taaataataa tcatagtctc ctagatagac tttgctgcca ttttcagaga
    11281 gttcgacgac ttttgtcgcg atccgattga tgaaatatcg gtcatgggaa acaaaaagca
    11341 gtgtgccgtc ataatcgatc aatgcatttt ctaatacttc tttgttgtca atatctaaat
    11401 ggtttgttgg ttcatccaaa atcaaaaaat tttctttgtt catcgctaac ttggctaaag
    11461 caacccgtgc tttttcaccg ccacttagca gagggattgg tttttctaca tcttcgccag
    11521 aaaataagaa agcacctaaa gcacttcgga tctctttttc tggagtggta ggatgctcat
    11581 cccacaattc tgctaggatc gtcttgtttg tatgcagatc agcttgacct tgatcgtaat
    11641 agccgatggt gacatttgtc cctagcgttt cttttccacg gataaaaggg atctggtgaa
    11701 tgattgattt cagcaacgtc gatttcccga taccattcgg acctactaga gcaatcgctt
    11761 cttgacgacg gatatctaga ttgattggtt cagataaggt gacattatca tatccgatag
    11821 cggcatcttc gatttgcaag actacatttc cagaaggctt ttctatactg aatagaaagt
    11881 ttgcttgttt ttcatcccct tgaggacgat ccagccggtc cattttttct aatgtctttc
    11941 tgcggctttg cgctcgtttt gtggtagagg cgcgaacaag gttccgagca acgaagtctt
    12001 ctaatttatg gatttctgtt tgctgctttt cataagcctt ccattcactt gctaactgtt
    12061 ctgctttcaa atctagatat ttcgaatagt tacctttgta atggcgcatt tttcttctgc
    12121 ttaattcata gacttcattg actactttat ctaaaaaata acggtcatgg gaaacaatca
    12181 ataatgcacc agtatagctt tgcagataat tctcaagcca ggaaagtgtc tcgatatcta
    12241 aatggttcgt tggttcatct agaatcaaaa tgtcagggtg ttgcaaaagc atgcgagcta
    12301 aagctaaacg tgtgcgctgt ccgcctgata aagtatcgat tttctgatca taaaatgaag
    12361 aatcgaattt aaacccatgc aatacggaac gaatttcatt ttcataacca tagccgtttc
    12421 gatctgaaaa atcgtgttgc agccggtcgt attcttttaa ataagaacta taagcaggtg
    12481 tgtctggcgt accttcgcta atgaaaatct ctagctcgcg catccgctct tccatttgtc
    12541 taacttgttc aaaagctttc agcatctcgt tccaaactgt ttcattggaa tcaagtcctg
    12601 tgtcctgagc gaggtatccg agagtcgctg ttttattttt agcgatcttt ccttcatcag
    12661 gtgcttcaat tccagcaatg atctttaata aagtcgattt tccagcgcca tttctgccaa
    12721 ctaaagcgac acgagcgcct gtactgattt ctaaatgtat gttttcaaat aagacttctg
    12781 caccaaaatg gcgagcaatc tgattggctt gtaataatat catggaatcc tcttttctac
    12841 tttgtgaatt ctcctcaaat aaaaaactat ttttcaatta gtagtctacc ataaattcca
    12901 ttatactgcg agatttgcag aaatgataaa taaatgaata aagaataaaa tttcacaata
    12961 tctgagcaat ggaattgatt ttttcctata aatactgcta tgatggagaa atcaaagatg
    13021 taattagaca atacgtggag gtcatttcgt gaaagatcat attattccaa aggcgacagc
    13081 taaaagactg cctttgtatt atcgctattt aaggatttta aataatgctg gaaagaaaaa
    13141 agtgtcttca actgaattaa gtgaagccgt tcaagtagat agtgcaacga tccgtcgaga
    13201 tttttcttat tttggcgaat taggaaaacg tgggtatggt tatgatgtag aagatcttat
    13261 gcactttttt gcaaagacat taaacgacga tcaattgaca aatgttgcgc tgatcggtgt
    13321 agggaacttg ggaagtgctt tactaaaata caaatcccat caaagtaata gcatacgtat
    13381 cagttgtgct tttgatgtga atgaggaaat cgttgggcgc atcgtagacg gtatccccgt
    13441 ttatccaatg gaagatatgt cagaacaaat caagatccaa caaatcgaag tagcaatttt
    13501 aacgataccc gctgaaagag cacaagaagt agtcaatcag ttaacggaag caggaatcaa
    13561 aggaatcttg aactttaccg ctgctcgatt gaatgctccg tcagatgtat tgatccaaaa
    13621 tgttgatttg acgaatgaat tgcaaacctt gatctatttc ttgcattctg acgcaaatgc
    13681 gcattccgaa aatacagcag aataaaaata aaaagcgatt gaacaaatga aggcaaaact
    13741 ttcacttgtt caatcgcttt tttctgtttg gacaacgatt attttgttcg gaagatttct
    13801 tcataagaaa gggaatcatc ttctgctgtc agttcatcta gtagataacg gattttttta
    13861 aagtcgatga accgtgcttg ccgaaagact tcttttcctt gatgaaaaat caggacaact
    13921 ggcgcagtca gcacttcaaa tttactagct acttctggtg tttcaaatgc atccaaatga
    13981 agtgccggaa tatcataatg tgtgagaagt tcctctagtc gtggacgaac agcgtgacaa
    14041 acactgcaat taggcatcga aagataaatg acggcaacgg atgactgttg cagtatgtct
    14101 tgaacttcag tcaagttagt ggtttgtttc atttttattc tcccttttat gatagaagtg
    14161 atatgtatga gaccttaatt taatgggaat aacagaaaaa gtcaattgaa gtgctttggt
    14221 aaaaaataag agttgtgtaa aaatttacag agcaacttgt tttttttgaa taaaagcgta
    14281 tatttgcaaa gcgaatgaac tagaaataaa aaggaggaaa ctcatgtttt cttttattcc
    14341 aaattcggtt ttgcagatga gtacgatttt cttatcgatc gttattgaag cattaccttt
    14401 cgtattatta ggctgtctta tctcaggcgc cttacaagta tttttgaccc cagaacgtgt
    14461 gaagagatgg cttcctgaaa atcgtatctt ctctattttt actggttcga tcttaggatt
    14521 tttctttcct tcatgtgaat gcggcatcgt accgatcgtt catcaatttg ttaaaaaagg
    14581 cgtaccagtt cacacagcgt ttgcttttat gctgactgct ccgatcatca atccaatcgt
    14641 gattttttcc acttttatcg catttggcaa ttcttggcag atggcaagct ggcgggtgat
    14701 aggcagcttt tttgttgccc ttgtgattgg tgtctggctt gcctattttc aaaaagacgc
    14761 tgtattgaaa gaaaaaatca cgtctaaagt agcagaaaat caccatcatc atgtccatga
    14821 agaagaacaa agtgagaaga atgaaccaaa aaatcagctg atccatcaaa ctgggcatgt
    14881 gttgacacat tcaatcgacg aattttttga tacaggtcgt tatttgatca ttggcggatt
    14941 aatcgcagct gcgatgcaga cttatttacc aactagaatt atgctaacgc tcggctcaac
    15001 aaagatttta gccattatca tcatgctgtt attggccttt acgatgtctc tttgctcaga
    15061 agcagatgcg tttataggat cttctttgtt aagtctgttc ggcacagcac ctgtagctgc
    15121 ctttttggtc tttggcccaa tggtcgatat caaaaatcta ctgatgatga aacgatattt
    15181 tacaggacgc tttattttat cgctgatcgg actgattgcc cttagcgtta ttggattcac
    15241 attatttatt taggagggaa aatatgctgc ggtttttgat tttatctggg tatttcgaat
    15301 tgatgatgta cttgcaagtt tctggcaaac tcgatcaata tatcaatgtc cattatcgct
    15361 acttagctat tctttcaatg attttatctg ctcttttggc tttagttcag ctgtatttgt
    15421 gggtcaaaaa cggaaaagca gaagaaaagg cacacgagca cgatcatgac catgggttgt
    15481 caaaacctta tcaacgtgga atcgcttatg tactgctagc tttgccagta atcgtgggga
    15541 cgttgtttcc aacagttagt ctcgacacta cgatcgtaga agccaaagga tttaatttcc
    15601 cagtaagtaa agaatcagta ggggatccgg agatgcagac acaatactta aagccggata
    15661 ccagtattta tttcaacaaa tcagactact tagaccaaat gaatgagttg aaagaaaagt
    15721 atggggataa gcaaactatc aagatcacag atgaaaacta tttagaagtt atggagctaa
    15781 tttataatta ccctagcgaa ttcattggca aaaaaatcag ctatgaagga tttgtttacc
    15841 aaacaccgaa cgatagcaat acagatatct tcttgttccg attcggcatt atccattgtg
    15901 tggcagattc aggagtcttt ggtttgttga cgcatatgcc ggaaggagta acggttaaaa
    15961 atgatgaatg gtataaaata gaaggaacca tccaatcaga ctattatcaa ccattcaagc
    16021 gtgaaatccc atctgtagtt gttacaaacg ctgagaaagt ctctgctccg aaaaatcagt
    16081 atgtgtatcg ttctttttaa aagaacaaaa taaataaaca tagctcagac agctgacacg
    16141 caaggacgtc ggttgtctgg ctttttttgc atgatgtatt catttgtttg atatttattt
    16201 tagaagcagc atcctgaaag tatttgatat cggtttcaaa ggtgttggaa aagattgtga
    16261 agagaattac aatttattcc taacatgtat gttgaaaagt tgtatgaaat gattttgata
    16321 gtaaaatatc gagtggaggt actttttatg gtaacgcgta tatttatttt ggatgatagt
    16381 ttggtttttg aaaaaatgct agtagaaatt ttggaagaat ccagaatttt attaagtcct
    16441 tggaaatttg agatcgttca gggattgaac gttatacaat ttgttgaatt cattaaaaat
    16501 aatgaaatct attcctcaga tatttttttc ctagacatcg atttgaacgc ctattatagc
    16561 ggtatcgaac taggcgaaat gcttagagaa aagaatgaaa agtgtaaaat tgtttatcta
    16621 acgtctcatc cgaataaagc aataactgtt attaatcgaa agattacgcc tagtggttat
    16681 ttgataaaag aattcactta tgaaaaaaat aaaaaaagca tccaaagtta cttattgaaa
    16741 gaaaaagaaa actatcctgt tcaacatgct acgaaaaaaa ggtggacaac tgtccgttat
    16801 ggtaatagcg atcactatat ccattacgat gaaatccttt atctaatgag catgccaggt
    16861 tataaaaata aaataggcct agtattgaaa gatgaagaga ttctcgtaaa cggcacaatt
    16921 aaaaaatata aaaaatcact cgaatatgag tatttatgta aagatttaaa agcttatatc
    16981 attaatactg aaaacattac atctattagc agagtaaacg aaatagtaac atttgcaaat
    17041 ggagaacaac tagagatggg aaagagaagt attgataaac taaagaattt tatgcaagaa
    17101 aagatagaaa atgaatcatt ttaaagaaaa caaagactca tatcttacct gttagaagag
    17161 tgttttcctg tagaagagaa caacccaagt agcagcctag tcgtttctat ccttttttgt
    17221 tatgcactct ttttgacatt tactccacca ataacgaagg gtacaataaa aagtaataac
    17281 aaacaaaagg agtacagaaa tgattgaatt catcaatgta agtaaaagtt acgggaaaaa
    17341 acaagcatta aaagacttgt ctctctcgat aagacaaggg gaaatttttg gatttttagg
    17401 acataatggt gccggaaaat caactacgat taaaagttta gttagtatta ttgaaccatc
    17461 atcgggaacg attttagtag atggaatgaa attgacggaa aatcgattga gtatcaaaca
    17521 aaaaatcggt tatgtgcctg attccccaga tattttttta caattgacgg ctggagaata
    17581 ttgggacttg atttcagctg cctatgaatt agacacacaa aaaaaagaaa agcgtttagc
    17641 agaattgaca gcgctttttg atatgtatag tcatcaaaat gaaacaatcg caagtttttc
    17701 acatggaatg cgtcaaaaaa cgattttgat cggcacgttg ctgccagatc cagatatttg
    17761 ggtattggat gaacctttgc aaggacttga tcctcaagca gcatttgatt tgaaagaaat
    17821 gatgaaggct catgccgcaa aaggaaaaac agtcattttt tctacacatg tattggatac
    17881 cgcacaacag ttatgcgata aactggctat tttgaagaaa ggtgaattga tttatcaggg
    17941 ggcagttagt gaattattga atggctcacc tgatgaaacg ctagaaaaga tttatttgaa
    18001 aatggctgga aggcaagcga caggagatgg accgtatgta taagcgacaa ttattagaat
    18061 taattcgagt taatctttta tatgttaatc cacagctcac gaataaagca agagagaaag
    18121 gaaaaaaggg aaagcgatta actatctatc ttttgtctca aaatcttttt tcagggctga
    18181 tttttttact gatttacgga tttgctatgt ttgctatgaa ctttgttaaa ttgccaggtt
    18241 tctttactta ttacgtggca ctttttggta tgttaggttt aactcaaagt atatcagtca
    18301 tttataatat cttttttgaa ggaaatgacc tgcaagtatt tttgcctctg ccttttggac
    18361 aagaacaggt tttttcagca aagattttgg tagttgcttt gaccatcatt ccttttgttt
    18421 ttccgcttct agtcatgttt attttaaccg gatggcgagc tgatctaggg attttgctta
    18481 ctatcattat ctcaatcctt ttgttttctc tatttttgat tattcttttt tgtctggcta
    18541 gtttgattgt ttttggtttg gctcgaacag cagtgtttaa aaaacataga aaaacagttt
    18601 ctagtatctt gcttggcagc tcgatgctga tcgcatttgc tggaatcatg tggatgaatc
    18661 atcaaacggg gactattgaa aatgagttaa cagatcggca tccgatttcg atattattgc
    18721 cattctatga tgctgccagt cagccacttt ctcaacaagg tttattgggt tggggaatac
    18781 tagctatcac ggctctggga tttttccttg ctgtaaaaca gctgatagta ccaaagctta
    18841 cagagcaact gactgattca aacagtgagt tcaaaataaa aagaacccat aaaaagaacc
    18901 aaaatgtgca tcagctttta tttagttaca atgctcaatt agtaaaagaa cctaatttga
    18961 ttatgcaagt tctttcttct tccttgttaa ctccaatcat ttttattctt gcttttgccc
    19021 taggaggcga aataaaatta actgatttag ataataagtt aatcggtgtt gttttcctgg
    19081 tagggatcgc attggctttc ttaacagtta atcagacttc ttttatcagc aatcttattt
    19141 ctttggatca agaaaatttt ctgtttatcc gttctttgcc aatctctatg aaccaatatt
    19201 taaaagaaaa gttcagattc ggatggatat tgcagagttt tttaactggt gggatcgcat
    19261 tattaagcgg actgtctttt cagctgcctt tgttttttat ccctagcttg ctatttggtt
    19321 ctttattcgg ctgctactta ttgtcactac gttatttcgc tagagattat cggttgctgc
    19381 tgctgaactg gaccaatatt aaccaattat ttaacagagg ttcaggaagt ttgggtttag
    19441 tcgcaactat gatgggttca ttgatcatca gtattattct tatcgtctta tacggaatgt
    19501 tggctttgtt ttatccattt tggttagtga atattcctgt gatcggttta gttctaatac
    19561 tttccgctct atggatcgtt tattatcaac gaacgttttg gaaaaaattt gaataaagaa
    19621 gaggggccgt gacaaaaatc atgtcgcagc ccctttttta cagatagagg gtgttcaaaa
    19681 gtcagtttct cagtattaag tcaattttat gtaaaaatgt gagaagctat ttttacaaaa
    19741 ctttttttaa tactcataat tacttcttat tgctcctgcg gttacttgtc gcaatgtttg
    19801 tgagatattt tgtcatcgct caaggctgaa cgtctctttc acaacctttt ctttgttaca
    19861 cttcgtttat ttaaaaagcc gtttttttcg tttcatcatg attgcgtcac gctttacttt
    19921 gaaattacgg atgttatggt taaagacttc tgataataca agacctaaag cgattgctcc
    19981 agcaatcata attgcttgga ccgcataatg agccgcttct cgataggatt cagtaacgag
    20041 atttcgaacc gcttgataag ctaaaccacc agggactaga ggaaccatcc cgggaatatt
    20101 gaaaatcgtt acgggcattt tcaaacgttt agagaaaaga tcgctgatga atgctactcc
    20161 taaagaacca agcaatgaac caaaagcagc agatccgcct atttgaacac agatccagta
    20221 gatcatccag ccaaaagcac cagaaagacc acaacaaatc aatgaacgcc taggtacatt
    20281 tgtaataacg gcaaatgccg cagtcgctaa aaaactaaaa gaaaactgaa taaatatcgt
    20341 ccccatactt gtgttccttt cctaataaaa aagctggaaa ataaaagcaa tcgcaaaacc
    20401 gatcatcgta gcagtcatca tcgcttctgt tccgcgagaa actcctgaga cataatgtcc
    20461 agctagcaaa tcacggatag cgttcgtaat ttgaactcca ggaactaaag gcatcacaca
    20521 tccgataatg attagatcct gattgcttcc taagccaaaa cgtacgctgt agatagcggc
    20581 tatgccaatc aataaagaag ataaaaattc cgataaaaat ttgattctaa aaaatttcaa
    20641 actatataga taagctgcgt atcccaatcc tccaatgact aaagtcacag gtaaatcggt
    20701 catctttccg ccaaataaca ccataattgt tccactgatc actgccgcgc taacgatttg
    20761 caaccagaca ggaaagaaag aacggtctcg gtcgattgct tgcagttcgc agtaaagttc
    20821 ttctaatgtt agctctgaag caacatattt acgtgaaaga tcatttactt ttactacttt
    20881 ttctaaatta atcgaacggt tggtaatttg ttccattcgg atggtcgagg tacgatcaag
    20941 accaataaag agaccggttt gagtgacata gctgaccaaa cggaaatttc cagaagctaa
    21001 agcaattcga ctcatcgtat cttctacccg atacatctcc gcattgcttt ccatcatgat
    21061 tttcccagcg agtaaacaag tgtccagcaa cagatctaat tcttttcccg tcatagcatc
    21121 ttctccaata attgattgat tagttttatt ttactacaaa acataccaga agcgtaaaga
    21181 ataaaaaaac ttgaggaagg aataaaagag gcgtatactg tttttgtatt gcgggtgtag
    21241 tttagtggta aaatcccagc ttcccaagct gatgtcgcgg gttcgattcc cgtcacccgc
    21301 ttaaaatagg ttgtgaaaaa gctgctctgc aacaagtaat aagaacagcc aagcaaaaac
    21361 aacttcttat gtttttaact tggatggact tattaccgca gatgcaagct tttgcgcacc
    21421 gtttaccaag cggttgtgaa atcagtgtat tgtcttgagt atgaagaaaa tttttgaata
    21481 ataataaata ccttacagat agagtggtga ctgattagag acgaggaatc cgtctctttt
    21541 ttgtattttt aagccatctt aaaacaggtt ttattttttg ctgtttctat ttctttctag
    21601 tatttattta taggggaaca tatgttaaga tttagggagc tgttagtaaa ggagtaaaga
    21661 aatgagcaaa aaaacaacca aggcgatcgt ggggatcgtc gctgctgtga ttgcaggggc
    21721 attcggtgtt tccaccacac aaaaagattc agatatcttt cagcagatta caactatttt
    21781 tgattccaca ccacaagctt ctcaagtagc ggatgtgcca gaatatgatg gaaaacatca
    21841 agaaatagaa atcaatggga atcagccgga atttacaaaa gaggatctta gcctttccaa
    21901 aggaacatgg gaaagctatt caaatattga taaattgaac agagtaggac aagccaatgc
    21961 tatgcttgga aaagatttgt tccctactga aaagagagag cctttgtata ttgacccgac
    22021 aggttggaaa caaaagaaat taagtgacgg gcaatggtta tataatcgca gccatttaat
    22081 tggtttccag ctgactggtc aaaataacaa cattaaaaac ttgatgacag ggacacgttc
    22141 gttgaatgct ccatacatgc ttgctcacga aaatgatatt gcggcatata tcaaagaaac
    22201 aaatcatcat gtacgctacc gtgtcactcc tcattttgag gggaatgaac tggtagccag
    22261 gggagtgcaa ttggaagcag aaagcattga agacaaaaaa attgaattca atgtctttat
    22321 ctacaatgtt caagatggct acacgatcaa ttatgagaca ggacaagcaa caaaaacaaa
    22381 aaattagtag cagctattcg aattttttat gaatattatg aaaaaattgt gtaaaaacat
    22441 acattcaaag aaatatagcg tatactttat gaaaagagta cttttgataa agctacagaa
    22501 aaaaggaaaa aaacatacaa atagtgtttc ttaatttatt cggaagtttg gaatatttgt
    22561 ttgtagtttt ccctttcttc gagtaaaata aggttgtaga aggtaagctg gaattacctt
    22621 gcgggaaaga ggtgtagaat catgggtttt acagatgaaa ccgtacgttt tggttttgac
    22681 gatagtcgca aaaaagaagt gagcgaaaca ttagcgattg tttatcgggc tttggaagaa
    22741 aaaggctaca atccaatcaa tcagattgtc ggctacttgc tttctggaga cccggcctac
    22801 attcctcgtt atcgtgatgc tcgaaatttg attcgccgtc acgaacgcga tgagatcatg
    22861 gaagtaattg tcaaggacta cctctcaaat catggagtga atttatgaga gtaatgggct
    22921 tggatgtcgg ttctaagaca gtaggtgttg ctatcagtga cccctttggc tggacagctc
    22981 aaggagtaga gatcattcgg atcaatgaag cagaagaaga gtttggcttt gatcggttga
    23041 aggaattagt agcacaatat gaagtagacc ggtttgtagt tggattacct aaaaatatga
    23101 acaattccat cggaccaagg gcagaagctt ccatgtcata cggagaaaag atcaaagaac
    23161 tattctcctt gccagttgat tatcaagatg aacgattaac cactgttcag gcagaacgta
    23221 tgctagtaga gcaggcaaat acttcaagag ccaaacgaaa aaaagtcatc gataaattag
    23281 cagctgtgat gatcttacaa aattatttag acggctcagg taagcaatta ttttaataat
    23341 aaaagaaaag aggtaatctt atgacagaac ataaccattc ccacgaccat gaaggacacg
    23401 aacacatcac attggtggat gaccaaggaa atgaaacatt atatgaaatc ctactaacag
    23461 ttgacggaca agaagaattt ggacgtaact atgttctttt atatcctgct ggtgtttcag
    23521 aagatgaaga tgtagaatta caagcttatg catacatcga aaacgaagat ggaacagaag
    23581 gcgagttaga acaaatcgaa acagacgcag aatgggacat gattgaagaa gtattcaata
    23641 cattcatggc ggaagaagaa gaatagacta taaagctagg agaaaccttg atatgatagg
    23701 gtttctcctt tttttatttt ttactgtatg ccatattgta tgccatctag tcaatattta
    23761 agtgttgtac taatttttca acagtctttt ctttcgtttc ttttgccaag tgaccgtaac
    23821 aatcgatcgt ctgactaatt tttgtatgcc gtaatctagt ttgaacttct accatagtag
    23881 ctccagcgtc caagagcatt gaagcatgag tgtgtcttgc tacatgcaca ccgagaaatg
    23941 gaaccatagc tttttcacaa atagtaatca atcttgcata aatagcgtgg tgtgtgatta
    24001 gttctttata gataccacaa aaaatcatag tcggatcagt tacaccaagt gtcagcatat
    24061 atttccgctg attaatctgc cattttttta atatagaaat tgttctttca tctagtggaa
    24121 gaaccccagc actacaatca gttttaggat cactgatttt atagccattt ttggattggc
    24181 ttagtgtttt attgatggtg accgtatttt cttgaaaatc aatgtctgac caattcaatg
    24241 caagggcttc actgatccta accccgctat aaaagagaaa gcgtagtaac gttttatcaa
    24301 agtcgtttcg ataagtttca ggtttgctgt ttaggtaatc aaacaaggtg atcagttgtt
    24361 ctttactgta aactttgacc ttttctttat gcttagtggt ggttctttta ggcattaata
    24421 cgttgtctag tggattagtc tcaataatcc caagattgat agcgtagcta aaaatacgct
    24481 tagaagttga atgaagtacc ttgtattggt cagtagtttc agcccagcta tttacaattt
    24541 gttgggcttt ttttaccgtg acttcattca cacgaagatt tccatatttt ggaagaatcc
    24601 actttctaaa cttgatttca gttttcatga aggtggcttc tcggacagtg gttttatatg
    24661 tttctagcca caagtcataa acttctttaa acgtttcgtt gttcgctttt ttaataccgt
    24721 ttttatcgta gtccacttgc aagcgtgaca aggcaagctg ggcttctttt tttgttttgt
    24781 aacctcgtct acgaacctta tcaggtttgc cagtcatttt gttcattcca agataggctt
    24841 catagagcca aaatttacct tttttagttt catattgctt gaatgttgcc ataatagttt
    24901 tccctccata gtgtagcaag ccgtgggggc ggttggagga ggcagtttat tattattttg
    24961 aatagtgttt atttagctca gtaacaagag ctgtgaactc ttttagaaga tcattttcat
    25021 aaaattcttg atactctttt ttctcatctg tatttttttc tgaatcatta attaatgagt
    25081 catatcgtaa aagcgtattt agaagagctg cgagataagc aattggggta ctcccgtcag
    25141 gaaattcaat tcgagatcct gttttaagat attttattgc gtttgttaaa taaatcttct
    25201 gtgagacagt caggttatct tcttcgatgt tattgatagc attagaaaga ttagaatcaa
    25261 ttatagagtt atttttttca atagtttttt tcaattgctt ttcaagcaca tttcgcttaa
    25321 tttcgggcat catatgcata tctcttaatg tataagatcc gtttaataga taggtagtgg
    25381 atacatctaa tacctttgaa agttgtttaa gcctggtgtt attgggaaga ttatagccat
    25441 tttcccaatt actaacggca cctttactgg ccggtgggga taatttacct ccaagttgtt
    25501 ccattgagag tcccttttca attctagcca gtctaattct ttgtcctgtc tccactgctt
    25561 cggggtattt ttttctagcc acattttcac caccattcat atattttctc tactatatca
    25621 cgatttaaat atgtgtgaaa cataaaagtt caaaaaagta tgttaaaatt cttgcaaatg
    25681 aaaaggtatg atggtatatt gagtttataa gaggtataga aatgtattca agagcctctt
    25741 gcattttttt aaaatctttg tatagaaatg tatgctaacg aggggggata aatatggaat
    25801 taaaaattga caaactcacg cttgatgatc cagcttttaa aattattgac gatcgagttg
    25861 ttcaacaagt agagcaaact caaggaacgt tactttcatt attagaaaaa aagtaccagt
    25921 ttccaaaata tatgaacaag gcacaagctg ctaagtatat gaacgtttca tacaatacta
    25981 tgatgcagaa atatgttcct aacggtttaa agttgattat agttgatgga gtcgtaagaa
    26041 tttcacaaga tgaatgtgat cgctttatgg aagaatacca aaaataaacg caagccgtgg
    26101 gggcaaaggg attaatagga ggaaataata atggaatcga cacaaaataa agcaatcgaa
    26161 aaagtattat caacaattct tacagaagac acagcggcag aattagcaaa cttggaaggc
    26221 aaagcgctag aagaaacgtt tgaatgtttg tacgaacaaa tggactatca aaaattgcta
    26281 ccacaagaac caacggtaag cggagtattg cgtggcttga acgatttagt acaagcagag
    26341 tttaaagaac gactttctat tgaagagtat caagaaattt tgtatcagca agttgagttg
    26401 ttagcgagct tgctagggct tgaactggag gacgttgaat gaaaactgaa atttggaacg
    26461 gacacattat aagatttgtc gatattaatg atgaatggtg ggcagtggcg aaagatgttg
    26521 cggaagcgtt aggtcttaaa caggttacta gagccattca ctctttgcct aaagatgggg
    26581 ttactactag taaggtcatc gattcattgg gcagaacaca agatgtaaac atcatcaacg
    26641 aaaaaaaata tttaccgcat ggcattcaaa agccgtaaaa aagaagccga ggcatttcaa
    26701 gactggattt tcgacatcat caaagaacta cgccagtcca caggacttga aggctttcaa
    26761 gtattccgca tgctagacaa agaacaccaa aaagaagcaa tgactaaatt aagccacgct
    26821 attactgaac caaaaccagt agactacatt aaagcgaatg tgatagccaa taaagctgta
    26881 tcaactattt atggtcattc caaaatggta aaaaagaaag atatgactcc tgaaatgttg
    26941 gttgatcgtg aacctatttt agatgagaca gtagaattaa tgactgttaa agaaaaatat
    27001 gggttgcagt tttcagtgag tgagaaaatt tataatcgtt ctgctgaatt gcagacaact
    27061 taggagcatt aacatgatcg agaacaaaga aaaagcctta tccataacag tcttggcgga
    27121 caggataaag gcaacttaat tgggataaaa cccgatattc tttgttccga ttataccata
    27181 ttaaaaaatc ggagggaacc attatgaaac gaaacttaat tataggaagc attttaatcg
    27241 gcggaatttt cggcttatta ccattaattg caaaaatagc tatctttgca ggattagcgt
    27301 tatatctctt cactgcttat gacgagtacg actatcaatt aagaactgga gggcataagt
    27361 agatgtacaa aacaaaacta ttaaaccaac tcgatagcct tgaattagag gaaattaatc
    27421 aagggatcgc tgaactagaa aataatatcg ggaaaaccta ctttggaaat tcattcaatg
    27481 aaaaactaac agttttgtat gtactcaaaa aacatgcaga acacaaaata atttgtcgag
    27541 aaatcaacga gctaaaaaat cagattttaa ccgcatggtt aaacattact gatatgcaag
    27601 aagcaagggt gaaaacattt aatacatggg taaagtatca gaatcaatta aaaggtgctg
    27661 aatttgttcg ggatgggttg aaatacgaac ttgagcagtt gaagctcatg gaggtgtctg
    27721 aatgatttat accagtattt tgaaaaagga ggagaggttt attggcaaat aattatcaag
    27781 cagcaacgga attacaaaag tcgggatggt caatttatcc cttatctcct ggaactaaaa
    27841 ttccaataaa aggctctagt ggttggaatg atgcaactaa cgattctaat caaattaatg
    27901 aatggtggac ggaagatgca actagaaata ttgggttaat gcttgaagat catcaaatgg
    27961 tggtagttga cctagatcaa cattctgaaa cacgaaacgg cgttgagaat tataaaaaac
    28021 ttgcttcaat gtatgatcca tttccttcta cttatacgga aatcacacca ggtaaaggaa
    28081 tccatttctt ctttaaaatt cctgatggtg taattatcca acaagaaaca ggtgcatttg
    28141 ctgatatctt cgggcgtgat gataaaggta aaagtttaag cgggattgat attatcacta
    28201 aaggagttcc aatagcgcca actatgatta tttcaagaag tgttgggaga gcatatgaac
    28261 ctattgaaaa cgtatctcta aataatattg caccagctcc cgattggcta gtgaacctac
    28321 tgctaaaaaa accgcaagaa ataaagactc aataccgacc cgtagcaaaa acagggacag
    28381 caaaaaaatt agatatgatt gttcaaggcg ctggcgaagg tagtagaaac gatcatttaa
    28441 ctaagttatg cggttggtta ctatggcacg gtgtagataa tcaaacttta gcagaattga
    28501 tttatacagc aaatgcgtac aatgaaccac cgctaaaaga taaagaagtg aatcaaatta
    28561 ttcgatcgat gattaaaaaa gatttgaggg ggaaagctca tggctcataa gcataaatta
    28621 gatagtattt tagactttcc cgaagccagc gagcgtgaag acaatatcat tgaattgaaa
    28681 acctggatgt cacgattaag atgcaataaa gacgatcaga ttaaaagtaa cagtgttgtg
    28741 aatgcagaat tgattttaac caatgatagc aatttagctg gaacaattgc ttataacgaa
    28801 tttagcggat acattcacct attaaaagat tctccttgga tcaatcgtac cgctggagaa
    28861 tgggaagaca gttttgagga tgccttaacg gcatatattg aagaaaacta caatgtagtt
    28921 tttgatgaca acaaaataca caaagcagta gtaaatgtgg ctagaaagaa tgttttcaac
    28981 ccagtaaaag aacgtatcga aaaagttaaa tgggatcaac agcctagact ggaaacactg
    29041 tttattgacc ttttaggggt agacgacaac ctttacacac gagaagtaac aaaacgttgg
    29101 atagtcggat cagtcgcacg tatctataaa ccaggaataa agtttgagat cgttccagtt
    29161 ttggatggac cgcaagggat tggtaagagt accgttccag cattacttta cacggatgat
    29221 tttttcaccg attcattaga ttcgctaggt gaaaagaaag atgattatat gcagcttcaa
    29281 ggcaatgtaa ttattgaact tggagaatta tcttcaatga acaaaactaa aattgaacag
    29341 ataaaaaact tcatcagtgc caagatcgat aaaattagac ctccttatgg tcggaatgtc
    29401 atagcttggg caaggcaatg tgtatttatt ggaacgtcga atgatgggca gtatttgaaa
    29461 gatgatacag gaaaccgccg tttttatcct ttgccttgta agaataagcc aaagatgaat
    29521 ccgtttaaaa caaaggatga atattttctt caagtgttag ctgaagcaaa ggtgcttttt
    29581 gataaaggac aacgaatcta ttttagtccc gatgaagata aagaagtctt agaaattgca
    29641 aaagactatc aagaggatgc caagatggag aatccaatta aagaagcaat cactaaatat
    29701 ttggaaatgg aaatcccgta taaatgggaa gaagctccag cgtgggcgag acgttcttat
    29761 tatcagaact atcctgacag taaatgtaat gagaaaaatt tacagcattt ctataatgga
    29821 gctactatgc aacaagagtt ttatttagtt gatagcgtac tcaccgctga tattttggaa
    29881 gctgtttttg ataaacaagc aaaggattta ttgaatggtc gatcagatgc agaaactaaa
    29941 aagattgcct tgattattag cagtattcct ggttgggaac ggaagcaact gccaaaaaga
    30001 aataaacgac gaggatttta caataagtca aatgcctatg aaaataaaaa tcgagctgga
    30061 aagtacaaaa agtaacgggt agtaacgggt cagtaacacc tagcccgtta ctagtttacc
    30121 cttactgccc caagggatac agcaatttgg taacggggta acaccttatt tccttaaaac
    30181 ttttgaaata gttagctaat atgctgggga ataatgttac tggattttac ccgttacctg
    30241 ttaccaaaac gctagaaccc ttgtccccgt tgggattgag tggtaacggg tacctgttac
    30301 gtaggtgtta ccacgtgtta cgaatcaagg aggaaagtaa atgctcaata ttatttcaac
    30361 aaacaaagca ccgaactttc aatatacaga tgaaatggat cggtttctaa tgaacacgct
    30421 ggcatttagt gtgggattgg taacagaaga ttattccaca tttgatccag aagtattaaa
    30481 gataatggaa gaagaacctg attggctgca ggagtcagta gcgtggtgtc aatcgctagt
    30541 agtgggatca ttggtagata gtggcaacta tgatgataca ggtgagctaa tggatgaatt
    30601 taattgtctg cttaacctat atgatcgagc gagacaacga gagcttacat cgaatgagga
    30661 taatttgttt ttaaacatcc atgataagtt cttggctttg ctactaacag atgatgaatt
    30721 gataactaat ttattggagg tagaataatt atgcatatgg aaagtattag atacttcgat
    30781 ggtgagaaac acattgagta ttcaaacact caagaagatg tagactttat tagttttgag
    30841 gaagataaaa tcactaaagt taattttaaa gacggaacgt gcttgaagat agtttcgcct
    30901 tatattgaat acaaatcaaa atgggaacaa gatgattctg acgaacgaga tcgctttggt
    30961 tggtaatcta tggcagttaa aaaacaatgt aatcatgctg gatgtaaaac attgattgat
    31021 tataggcaga agtattgtgg gaagcataaa gcaaagcaaa cggcaattaa gcgtgaagaa
    31081 agaaagcaaa gcgaaggtaa atattttcaa ttctatcaaa gtagaacatg gcgaaaggct
    31141 tcatacttgt atcggttaaa tcatccagta tgtgaggatt gcctagaaga aggcttgata
    31201 aggaaagctg atgttgtaga tcacaaaatt gaactaaaag atgattggaa tagacggtta
    31261 gatgaaacta attttcgttc tttatgccat gcacaccata attccaagac agccaatgaa
    31321 agacaaagac gagaaaagag taccctttga gttaaggggg catagtgtga aacttactga
    31381 caatcgatgc ctactcattt tggtacaaat aaccgttgtg aaaaggcata agggtaatta
    31441 caaataacga ttacacttgt aatcacaagt gaaaaagtat ataatgaaag taggagattt
    31501 attgaaaaat acaattgtta ttactgataa aacagggaaa cagcgcacca ttgagttacc
    31561 tcattttggt caagtgacca ttcaaatgca gaacggaaaa atcatttata tagataaatt
    31621 agataaagaa aaattctgat cgaaaaacga aggaatgtga gcttaattgc ttacgttcct
    31681 ttttcttttg tctgaaagga ggacaacatg ggacacccta aaatattaca cgatacaaaa
    31741 ggcaatatat caagtgaaga aaaagcaatc cgtgtggacg ctagagaaga attgttcaag
    31801 cagcaaccat taataaatat cacgccccct gactggatgg cagcgagcgc tagaagtgaa
    31861 tggaatcgta tcgtaccaac attaaaaaaa gattatccat tgagtgaagc agattatggt
    31921 tcattggtag cctattgttt agcctttgct cgaatgaaaa cagccgaagc cgagataaga
    31981 aaatcaggta cgtttatcac atgcgaaaac ggagtaaaga aagccaatcc agcggttcgg
    32041 gttcaatcac aagctatgag tgatttgaaa aaacaagcca cctcactagg tatgacctta
    32101 gaatcacgat caaaactagc tttgaacaag gttaaaaatg atgaacccga agacccgttc
    32161 aaagagttga tgaattcatg aatgattaca ttgagaaagt cctatcaggt aagctgattg
    32221 cacccaagaa aattatccaa gcgtgtgagc gtcatataag cgatttggag cgttctaagt
    32281 cagatagctt cccttatgtg ttcgatgaag aacaagccac caaagcgatt aaattcattg
    32341 agttgctacc atctacggac ggtaaagcaa tcaagatgtt aggatttcaa aaattcattc
    32401 taggcagtct ttatggctgg cgtactaaag aagggaatta caggcgattc aatcgagcgt
    32461 ttaccagtat gagccgtaag aatgggaaaa cgtatatcgc aagtggcatg gctgccaatg
    32521 cgttgattat ggaacaagaa ccagcagaag caaggcaagt attgtttgta agtaacgctt
    32581 tgaaacaagc taaattgggc tatgatatgc tgtctaattc acttagaaac gtggtcaagt
    32641 ctagtaagtt tttaagacca caactgaaaa ttatgaactc taagattcag cacttgccct
    32701 ctaattcgtt cgctatggca ctggctagtg aaaccagcac gctagatggg tttgcaccaa
    32761 caaccgcaat tcttgacgag tggcacgaag caaaaactcg taaaacgtac aacgtcatta
    32821 agtcaggaat gacccaacaa aagaacggct tattgtgtgt tattagtacc gctgggcttg
    32881 atttaaacgt tcctatgtac gaggaatact tattgttaga tcgtgtgcta aaaggcgaag
    32941 aacaagccga caggtacttt atagcgatat gggaattgga cgatcccgaa gaaattcacg
    33001 atcaagagaa atggatcaaa gccaatccga tttttgaaag tgaagaaatc aaaaaagtaa
    33061 tgattccaac cattcaagat gatgtgaacc ttgctttgaa acaaaataac cttaattctg
    33121 tattggtgaa aaacttcaat ttatggagac aagcgagtga ggacagctat atgattgctg
    33181 aagactggca ggcaaccgaa gtagaaccac aagatattac aggcaagccc gtttatatcg
    33241 gagtggattt atctaaaaca gatgatttaa ctagcgtttc atggatcgta ccgctagata
    33301 acggcgaact ttattgtgat tcacatagct ttgtagccac caaatatggg cttcaagaca
    33361 aagaaaagcg cgacggtttg ccttatcgag aactagaaaa agctggtgag tgttccatta
    33421 ctcaattaga aagtggaatc gtggactatg accaagtatt tcagtttatt caagatttga
    33481 ttcaagaaaa tgatttggaa tgtatgggga tttgttatga cccgtataac gctaattcgc
    33541 ttatcagtaa agctgaaaaa gccaactacc caatgttaga agtaagacaa ggaacgatta
    33601 ctctaaacgt tccgacccga acttttagag aacaagttta tgaaggcaac gttattcaca
    33661 ataaaaatac gattctcacc catgcagtga acaacgctat tttaaaaacg gataacaacg
    33721 gcattcagat taataaatca aagaacagta acaaaattga tccaatagct gcattaatca
    33781 atgcctatgt gtttgcaatg gattacttca ccacaacgga aggagcgaaa gcagacaatg
    33841 aattttatac aagtgaagaa ttttctttct aattacattc ataccgttct tttacttctt
    33901 ggattggtgt gtgtgttggt tgctatcacc ttactaacaa atgtctacta tggcttgtta
    33961 gcgctgggca tagtgcttat tggggtagcg gtcatgctaa atacagaaca gaagggaggt
    34021 taaaagatgg cattttttaa agcgagacaa aatacaacgg gagatccttt cctacaacat
    34081 gtggtatcaa tccaatcgga tgattacacc accagcttta caagcgttcg tgcattaaga
    34141 aatagtgatg tgtttgcagc cgttcgaatt attgctagtg atattgcttc aagtccgatt
    34201 caattggtca aaaacaatat gccacaagct gataatgaac tggtgaagtt actaaacgag
    34261 aaacctaatt cagaaatgga tggttggcat ttaaagtttg ctttggcggt caatatgttg
    34321 ctaaacggta atagctttgc agagattaaa cgcaacggtg aaaaggtaga agaaattcac
    34381 ttattaccta actcaagtgt aacggttact caattagata atggtacgtt gtcttatcag
    34441 attggtgata aaaaaagacg tgtgaagtct agcgatattt tgcacttcaa atatttcacc
    34501 caagatggtt taacaggatt accaccactt tatgcgttac gtgatgaact gaaaattcaa
    34561 caagctggca accgcacatt gcacaatttc tttactcgtg gtgtcagtgg gtcaggtatt
    34621 ttgaaggttc ataagtcaga tttagacgga tcagcaaaga acgcaattcg tgaaaagttt
    34681 gaagaagcca acggttcaag tagtggagat aatgctctta gaacgatcat tcttgatgaa
    34741 acaatggact acaaaacatt agaaataaac accgatgttt tgaagcttat caattccaat
    34801 gattggaaca caaaacaaat tgccaaggcg tttggtgtac cgattgagcg tttaggcgtt
    34861 gaaaatgaac attctagcac cgttcaaagt aatctccagt atatccaaag tacgctgatt
    34921 cattacttta atgtgtttgt gagtgaatta gatacgaaac ttgaaaccaa tatccgcttt
    34981 aattccgatc agttactaga gactgatcct gaaacaaaag taaaaaatgt attggatcag
    35041 gtcaaagggt cacttctcac gattaatgag gggcggtcga aaatggggct accccccatg
    35101 gatggtggcg atcgtttact agcaagtttg aactttacgt atttagatac gttggagaaa
    35161 tatcaattaa aagaacagga aggagttaca ccagttgaat aatgaagaag aaaaggaaaa
    35221 acggctgaca gaagaagctg agctaacagc cgattctccc aaagtagaga aagaaaatga
    35281 aaaacaacca acagacggca aaactatttc aggctatgcg ttgaaattcg ggcaaccgtc
    35341 aaaagattta ggcggctttg tagaagtgat tacacccgaa gcattaaaag aggtggattt
    35401 atcaaatgtg ttcttattat atggacacga ttattcaaag ccactagcta gtgtcaaagc
    35461 aggtacgttg aaattgaatg tcgatgatac aggattacat tttgaagcag agctaaccga
    35521 cacgacctat tcaaatgatg tgtatgagaa tatctcaaaa ggggttgttg attctatgtc
    35581 ctttgggttc gtgcttggat tagattcatt cgacaaaaaa gaagatggca caattgaacg
    35641 atcaatagat aaaatcaaag cacttaatga aattagtgtc gtgaccgttc ccgcttatga
    35701 ttcatcaaat gtccaagtaa ataagcgttc ttacgaatcg tttatgagta acaaccaagc
    35761 aaaacaaaca aacaatagct tagaatccac ttctaaagca caaaaggaga gtaataacat
    35821 ggaaaaaact ttaatcgata acgaaaaaac agaattgcgt gggtatgaag aatatatccg
    35881 ttcacaaggc gaagtgcgtg atggagtcac tactgtaaat gcagcggcag ttgttcccga
    35941 agaagtaatc ggtgaagtct ttgatttgaa acgttcaaat tataacttag ctcaatatgc
    36001 aacagtaaaa acagtatcaa atggacaagg taaatatcca gtagcaacta accaacaagc
    36061 agtgttagca acaaaagctg aacttgctga aattggtgat attgacgctg aaatgtttac
    36121 ttcagttgat tataaagtag aaactcgtgc tggtaagatt gccttatcaa atgaggttgt
    36181 ggaagattca gcagtgaata ttgtacaaga ggtcaaagat cagttagcga aattggtaga
    36241 aaacactgac aataagcata tcatggattt attaaaaaca ttcactaaga aaacggctgc
    36301 tacgttggac gatttgaaac aactatacaa tgtggcatta gacccagcat taaataaaat
    36361 ggtaattcta aaccaaagcg gatattacca cctagataca ttgaaagatt cagatggacg
    36421 ttacatttta caacccgatg tgacagcacc tagtggtaaa tcattattcg gtatgccagt
    36481 agtattgatt gcagatacat tgtttgccaa tcctaaagct ggaacattcc ctatgattat
    36541 gggggatatt gcacaatcta tctttgttgc tcgtagaaat caagtaacga ctcaatggga
    36601 aaaattcgat tactactcac aaggacttgc agtgatcgtt cgcaacgatt ataagaaaat
    36661 tgatcaaaat gcttcagtgt atattgagtt tacgccagtt gtaacaccaa aagtatagaa
    36721 aaatattggg cggcggttta tcccactgcc tttttttcat taggagagat aaaatggtaa
    36781 ttttggatag cataaaaaaa agtatgcgga tcgatcacac tattgatgat gactttattc
    36841 aacaattgat tgatacagca ggcgaatata taaaaagtgc tattgatagt agcgcaacgg
    36901 ataaagatat ggataattat cagcaatttg atttggcggt gtcattactt actcaacatt
    36961 ggtatttgaa ccgtcaagaa gccagcagcg aacggatacc agtaacggta caagcattag
    37021 tacaacaaat gagaggtgct tattatgcca atcattaaga atgtaaatga attgactgag
    37081 agagtcaagt ttaaaaagac aaaacgggta aaagatgaag atgggcagat ggtggatagt
    37141 gaagaaactg tatttgaatg ttgggctaat gtgcgttcac aaatgctaaa agacgtgctt
    37201 gctagtgtag gtaccattct tgaaggaacg ttgacgttta ttattcgata cgatcaagat
    37261 tatgaactaa caaacgatat gaaagtagct tggaaaaaca agagttataa aattatttca
    37321 atcaatgaag gaacggcgtt taaagattat acaacgatca tagctaaaca gatttcttag
    37381 aatgattaca cttgtaaacg ttgtgggtat ttagtataat taaggtagta aatgaagggt
    37441 tagctgcctg aattttgcaa gacttagcta gtcgaaatct attgttggac tgaaaattgt
    37501 aggtgtggtt gcaaacatgc tggactaaga aagatgatag atgatgaacg ttcaatttta
    37561 atacaggcat gctaggactg attggatggt tttggcaagc tgattgtgta gaaatcaaag
    37621 aacacgtctg ttgtggacgt gttttttttg ttataattca aaagaggtga tttaatggac
    37681 aaagcagagt ttacaaattt ttattggaag tattatctac atttagaaaa tgagtttatt
    37741 aataccacag attttgtgat gctcgatgag aataatttca aaacattctc tattgaatat
    37801 caaaaactac tactagcgat tggttcggag tgtgagatta ttttcaaaga actttgcgga
    37861 tttgatagca gtagcaataa aagcataact gattttaaag ctgttattaa atctagcgaa
    37921 ttaatgtgtt tggataatgg tgttagggtt atgaattctt taacattgac ttcactaaaa
    37981 ccttttggag atgggtggcc tgaagataca ccagattggt ggaaaatata taacagagta
    38041 aaacatggtc gttcttcaaa ttataaggaa gcaaatttgg aaaatgtgtt gtatgcttta
    38101 gcaagtctat atttattaga ggaatatttg cataagaaag taatactaga aggtgaagta
    38161 gactttataa gtccagagtc aaatctattt acgttatctt gggaaagaaa acattcgtcg
    38221 atgcaaaaag tgacgtttga aaaagtggat tcaaattatg tagctccact cattgatttt
    38281 aaagaacaag aagaaattta aaaaccccca cggcttattg aagtttttgt atgccatatt
    38341 gtatgccatt tggtttaaat cgcttgaaaa atagtgatag ataactctaa ttcatttagt
    38401 cataaacgct gttttgataa cctttatagt tctttgatat gggtttctca ttcatggcgg
    38461 aagaagaaga atagaacaaa agaatgaatt aataagatat aaaaaaaggg attgtgacaa
    38521 acgtcttgtc acaatccctt tttccaaata aacgatgttc aatcagctgc ccctcggcat
    38581 tcgctcgaaa aacggcgaaa tatgaagaac tattttgcca tttgtttctc taataatcag
    38641 gtcaaaacgt tgacttcaca gtctcttcct taaacggtgt tctcctgcca actcctcggt
    38701 cacaagtcac aatattcaac aaacatgaga agctgttttt tgaaattgtt ccttgtgact
    38761 cggagctgaa cggcaggctc acgacctctt tcttaaacgg tgttcaaaag cttgcatctg
    38821 cggtaataag ttcaaccaaa cgaaaattat gaggagctat ttttgtttgg ctgttcttat
    38881 tacttgatgc aggacagctt tttcacaacc tcttttcgtt tagcactaaa tttccttaaa
    38941 aagtagaaaa gctttcgaag cctcgtttgt ttcttttact gtataataaa agaaaagagt
    39001 aacaatcgct aaaagatata aacaagagaa aggaaataca agatgattgg tctgatttat
    39061 tttgtggtga tcgttctggc gaacacagtt ggcgctattt ccgggatggg tggaggcgtg
    39121 ttgatcaaac cgattcttga tcttatcggc gcccattctg ttgcagggat ttctttttac
    39181 tcaacagttg cggtattcac gatgtccatt gtttcgactg tgcgacaagt atcaagcggg
    39241 aaatcactga attggcagat tgtcggttgg gtatctagtg gagctgttgt tggaggagta
    39301 gtcggcaaca ttgtattcga agttttttta cagttatttg aaaacgagaa gcatgtgcag
    39361 ctgatccaaa tttttttgac ggtattgacc ttggtttttg cgttcttcta caccaagcat
    39421 catcagccaa aatttcattt gacgtcatgg acttggtacc ttatatgtgg gggggttctg
    39481 ggctttttag ctagtttttt aggtattggt ggtggaccag tcaatgtttc tttgttgatg
    39541 ctgatgtttg cattgccaat aaaagaagca acactatatt ctctatctac gattttcttt
    39601 tctcaactgg caaaattggt aacgattgct ttaacaagta gctttatgcg ctttgattta
    39661 tctatgttgt tttatgttat ccccgctgct gttattggag gtttgtgggg agcaagattt
    39721 agcagggttt tgtctccaaa aaaagtgacc tttatttttc aagtaattgt cctcgtggtt
    39781 cttttggtca attgttacaa tgcctttgtc atcttacaaa cattaggaga atctagacta
    39841 acgcaagtca aaatcactga aacatattgt tctaaatgaa aaaaagagta tactatgata
    39901 aaaaaattca ttttaaaaaa tcagaaattg gctggtgatt tggatgttac gggaaatgcg
    39961 tttagaagat gcagaagcac tacgtgaaat caatgcggat caattagggt atgatatacc
    40021 attaaccgtt acggtgagac aaatgaagaa actgctgaag gagccagaga aaaatttttt
    40081 cttggtttat gaagatccta cttctaaaaa agcagctggc tatgtacaag cggagtccta
    40141 tgaatcgatt tttagcgatc caatgttcaa tattatggca cttgctgtgt ctaaatatgc
    40201 tgaaaaaaga ggcatcggaa aggctttgat gactggcgta gaagaagaag cgaaaaaacg
    40261 aggaataacg acaataaggc ttaattctgc agaatacaga gtagaagcac accaatttta
    40321 tgaacacatc ggttatcatt ccgataaaat gcaaaaaaga tttttgaaaa tcctgtaaat
    40381 ctttatcaaa aaaatacccg atcaccaagc cgatacttga tgatcaggta tttttgtttt
    40441 tttgactaag aaagtaattg catcaagaaa ccagagatga tcaaaacgat ggcaccacca
    40501 agtcgattgc ccatttgagc aaaagcaata agttccatcc gattagctgc agataagacg
    40561 gctacatttc ctgttccgcc catcgagttg ttgcataagc cagcagtaat agttgattca
    40621 attggatata aaccaaacaa acgaccgaca aatcctgaaa caactgaaat cgcgataaca
    40681 cttgtcagac ataagacaac aaattgccat gtcaaagcag aagctaatac attcagattc
    40741 agcaacgcaa taccgatacc ggcaagaaca gctgctgtca agtttttgac aatcaagtta
    40801 ttgaacatga tagctgcatc ttcataatac tctggtaata ggttggcgat tttacagatg
    40861 acaacgataa taatcataaa tgcgtaagca tggactttag gaacaaaata gttaccaatt
    40921 tgtcctaaga tgaagaaagt caatgatacc atcaaaccaa cacctaactg tggaatggaa
    40981 ggtttcacag ttcgaggttt tccatcgcca agatcgcctt tttccattaa tttaccattg
    41041 ccgttgaatt ttggcattga ttgtccagca cgagcaacta atgctgcacc gatgatagct
    41101 aagacatttg tcattgctgt cgcaggaatc aggcgggaaa tgatagaaga agcatccgta
    41161 cctaaaacat ttgcataaat cgttgataaa ggaacggctc cggctccaac accaccagcc
    41221 atcgcaggta atgagatgta taaaacggaa tttgcaaaac catttccgat aagcatgccc
    41281 acgagtccta cggcaaaaaa ggagacgacc attgaaataa gtgcaacggg aataaaacga
    41341 acagaagctt tcatcaatag attacggttc ataccaagga tgctaccagt aatcaaggca
    41401 gcaatataaa agtcccaaaa gcccatattg ctgacaaagt tttctgtgga tttcactaca
    41461 tattcaggta agatcccaaa tgtagcaatc gcagcagaag cgaagatcgc aaaaacggaa
    41521 ccaccaccca aataactttt gacgataggg atttttgtcc cgataaaatg aaataaatta
    41581 ccgaaaataa ccaaaactgc gattggtcca atcatattcg tcggtaattt ccctaaagcc
    41641 attgcaatga tcaggacaag gaccatgatc aaataaagtg gcaaacttac gccggtgatt
    41701 tttgtggacc aaaaaccttc ttttttcttt tcctcaactg cagttgcagt tgttgttttt
    41761 tgtgccattt ttacagatcc tttcttattc tgtatcatat gaaaaaagcc aaagaaaagc
    41821 gacaaaagag caggagttgg ctggccgctg ttttgccgca gtcgcttttt tctttttaga
    41881 cgtcatacaa agtttctgta tgttctttta ctataacgat cttaatcttc taaagattta
    41941 tattcaggaa cccatttagc agattcaact gcttctttga tatccgtgat ttcttcacga
    42001 ttcaagtttt gtgcgacaac tgattttgcg acagtttcag caatcgtttg agaaaattca
    42061 gtgatttttg ctactggagg caagatagct gctcctggtt ttgttacatc aacgattccg
    42121 cctaatgctc gactagcttg agaaatgatt tcagcattta ctcgtgtagc tgttgaagca
    42181 atcaaaccaa gtcctaaacc tgggtacatc aaagcattat ttgcttgacc gatttggtaa
    42241 gttacaccat tatattcaac atcagcagca gggatacctg ttccaactaa tgcttttccg
    42301 tccgtccatt ctattaaatc ttttgctttt gcttctgcca attttgttgg attagacaaa
    42361 ggcatgatga tcggacgtgg tgtatgagca gccatttctt tcacgatttc ttcagtgaat
    42421 gctccaggtt gggtagaagt accaatcatg attgtcggat ggatcgcttt tacaactgct
    42481 tctaagtttg tcaattcatc agcattagtg aaatctgagc gtttgcgagc gaatgggatt
    42541 tgaccaggag tcaatccttc tgtatcttca aacaataaac cttgtttatc tacttgatag
    42601 aaatgttggc gtgcttcttc ttcaggtaca ccttgacgga tcatctcatc taaaaggatg
    42661 tttgcgatac ccacaccagc agtaccagca ccaaatgtca aaattatttg atctttcaat
    42721 tgttcaccgg atatattcaa tccgcctaat acacctgcta ggacaacaat tcctgtacct
    42781 tggatatcgt cgttgaaagt agtgatttga tcttcgtatt tttctaagat cgctgcagca
    42841 tttcctcgtc caaaatcttc ccaatgcaat aacaattctg ggaataattc ggtagctgat
    42901 tgaacgaatt gatcgatgaa ttcatagtaa gtttcgcctt ctacacgagc atgacgattg
    42961 cctaagtata agggattatt caataattct tcattattag taccagcgtc gatcgataca
    43021 ggcaaaactt gtgctggatt aataccagca gcagcagtat agaccatcaa tttgccgata
    43081 gcgatgtcaa caccgttcac accccagtcg cccataccta agattccttc tgcatcagtc
    43141 acaacaatca aacgaatgtc tcgtccatct gccgcgttct tcaaacttgc tttgatgttt
    43201 tctggttcgt cgattgaaag aaatgcagca tcttgcggtt tcaagaaaat ttcgttgtat
    43261 tgttcgattg aatccgcaac gacaggatca taaacgacag gcatgaattc aactaaatgt
    43321 tcgcccatca atttataaaa caatgtccga ttcgtattga atagattcat taagaagata
    43381 cgtttttcca aatctgtttg tttgcttaag tattgaccat aagcttgaac agattgttgt
    43441 tccagtgttt ggacagtact tggaagcata ccagtgattc catattttgc ccgttcttct
    43501 tttgtaaaag ctgttccttt atttagaaaa ggattattta ataagtttaa ccctgtaagc
    43561 atgaatgatt cctcctaagt tttaatacaa acgaagtata gaagtcagat gatgatatag
    43621 tcaaaaagag caggtatgat aaattttatt tatatgtaat atagccaaaa gaaatcaaaa
    43681 tagcagtatt tgttcttttt atatcgacaa tccttgcttg aatactatgc gtatctctta
    43741 tatgctagag aaagaaaagt agaagaataa gggatagatg gaatggataa ataggatttc
    43801 tgaggaaaaa agcacatgat agcgttgata ggagtcacct atgtcaggtg ataaaaatac
    43861 ataagtagaa aattaagagg aggaagagaa aatgaaagaa gttcaattga ttagaaaaag
    43921 cgaactatca gaaggcggtt gcaatgcatg tggcgtagta gaagcgacaa gctatacatt
    43981 aaaattagat tccaatcaag caataatctc tgaactgaca gtaggcggtc ttgtggacag
    44041 tctggcgctt gctgaaggtt ttactggaga agatatttat gagatgtttt cagaagtccg
    44101 tcagttaaaa aaaggagaaa aatgcataga ggttcatcat gagagcccga atgtgaggtt
    44161 caaacgtggt gataatgaga tgatcttcaa gaatcatgtg tctgatcaca ctgaactata
    44221 tgaaatcgtg aatcaaatac tgtctgggat ttttgaatta ggaccttatg agttcaagga
    44281 agaaaacggt aatccaaaat taaatgaaga atggcaagaa acgattgaaa cacaaagaaa
    44341 caatccacac ttatttcaat agtcttccac agtatttcgt aaaaatgttg atgaaaaaga
    44401 aacaccgtga atcagaggtc gtgaaaaacc tgccctgcat caagtaataa gaacagccaa
    44461 acaaaaatag ctcctcctat ttttcgtttg gttgggctta ttaccgcaga tgcaagtttt
    44521 tgaacaccgt ttaaggaaga gactgtgaag tcaacgttct gacctgagta ttagagagac
    44581 aaatggcaaa atagttcctc atattttgcc attttttgag ctaataccga gggtcagctg
    44641 attgaacacc gttttatcga gaggttgtga aaaagtcgct tagtttcgag tagtaagaaa
    44701 aattttgtga aaatggcttt ccacattttt gcataaattt gacttaatac cgagaaaatg
    44761 gcttttgaac accgtttatt caaaaaaagg gactttgaca ctacttttgt caaagtccca
    44821 tcggtttttt atctattttt attacaatca tttcttccag agtagtgaca tctggaatgg
    44881 ctgaaatgta aacagattat ttgcctgtat caatgtcgaa gagtaatata aaaagtgtaa
    44941 acgctatcat attgttcatc attcaaattt tatagagaga aggcattgag atggaaaaaa
    45001 catatcaagc aggtacaaat gaaggaatag tagattttat caatatggaa gatttagaaa
    45061 tcgcggcttc acaagtgatt ccagctggtg gttatggtta catcagcagt ggtgctggcg
    45121 acttatttac ttatcaagaa aatgaacggg cattcaatca tcgtttgatt attcctcatg
    45181 tattaagaga tgtagaatta cccgatacaa ctacacattt tgacgaagaa atgctgactg
    45241 caccaatcat catggcacca gttgctgctc atggattagc tcatgtgaag gcggagaaag
    45301 cttctgcaaa aggtgtagca gattttggga cgatctatac agcaagttct tacgcttctt
    45361 gtactttaga agagataaga gaagcaggcg gggagaaagc accgcaatgg tttcaatttt
    45421 atatgagcaa agataatgga atcaatttgg atattcttga agtggccaag cgtaatggag
    45481 caaaagcaat cgtattgaca gcggatgcaa cagttggcgg aaaccgtgaa acagaccgca
    45541 gaaacgggtt taccttcccg ctgccaatgc cgatcgttca ggcttatcaa tcaggagtag
    45601 gccaaacgat ggatgctgta tataaatctt ccaaacaaaa acttagtcca aaagatgtag
    45661 aatttatcgc tgctcattct gatttgccag tctacgtgaa aggtgttcaa tcagaagaag
    45721 atgtctatcg atcattagaa tctggtgctg gtggaatttg ggtatctaac catggtggcc
    45781 gtcaattaga tggggggcct gctgcgtttg attcgttgca atatgtggca gaagcagtag
    45841 ataaacgtgc accaatcgtg tttgacagcg gtgtacgacg tggacaacat gttttcaaag
    45901 caatcgcatc aggtgccgat cttgttgcta ttggcagacc cgttatttat ggattgtctt
    45961 taggaggaag tacaggagtc catcaagtgt ttgatttctt taaaacagaa ttggaaatgg
    46021 tcatgcaatt agctggaaca caaacagtag aagatatcaa aaaaataaaa ttgcgtgaga
    46081 atcgttttat ttaagaaata aatgacgaaa aaaataggag tgcggcagat gatgccgtac
    46141 tcctattttt atagttcaag gatgtcacta atagaataat ttgaaacgaa aaaataaaat
    46201 tgaaatattt tttcatactt aataaaaaag gaagaatatt catgtaaacg attttattgt
    46261 ttttttctct tttatacaaa aagggtcata atttcaagta agcggatgaa ttcatgagga
    46321 ttttttgcat actgtctcta ctatacttag gtcactaaga aaaaggagtg atttattatg
    46381 aaaaagaaca tgattgggac attattactt tcaacacttc ttctaggcgg cttggcaaca
    46441 ccagcttttg ctgagggtca agcgacttca aaaggagata ttacctttac tgaaccaaca
    46501 aataccgttg agcctcttaa ccctactgat ccttcaaaac cagtagagcc agcagatccg
    46561 gaaaatccag caactggcca gacaggttct ttaacattgg atgtagttcc tgaattgcca
    46621 tttggtacac acgagattga aagcggaaca aaaacgtatc aagtagacgc ttcaaaaaac
    46681 gatacacctt atctccaagt atcagatcgt cgaggtgtag gtgcagatgg ccaagcacaa
    46741 gggtggaacg tgacagtttc ggtttcagat tttgtaaacg gttcacaagt tttgcaaggc
    46801 gctgaattag attttggaac atccactgtt aaaagtacgt cagataacga atccactgga
    46861 ccaactagtc aaactgtaac tgggttgagt aaagcaagtg cagcgacacc aatatttaca
    46921 gcagcaaaag atcaaggtct gggaacatgg ctttctgttt atgatccagc aaatatcaca
    46981 ctgaaagtgc cgaaagcagc agctggaaca ttcacggctg atttgacttg gaacctcgtg
    47041 gctggcccag tagcatagag tatgaaataa attcaacaaa ctgcggtgaa aatactatag
    47101 gtgaaggatt ttttaccgca gttgttgttg aaaggatgtg gtggacaatg aatcaaagta
    47161 aacgactgtt tgtttcgttt ttttctattt taagtctatt tttcattttt ccgtcaatca
    47221 gccaagcaaa ggattcagca ggagactttg gaatcaaacc ggtatttcca gagaaccaaa
    47281 tagataaagc aatcggttat tttgatttat tagtggcacc ggaacaaaat cagacactag
    47341 aagtaattat cagcaattct tcagatgaag aacgaacatt tgaggtctct gtcaatccgg
    47401 cggtaacgag tgatggtgga acgatcgatt atagtcaaaa aaacccaacg ttagatgaga
    47461 cattgccgtt tgatgtccgt gacgttttgc tcattgcgaa aaaggaaatc aatgtatcag
    47521 cacatgcaga aacaactata cctatagaag tgaaaatccc agcaaaaagc tttaagggac
    47581 gtgtattagc gggtattcat gtttcaccta aagaagaagc tgaaacagaa aatgctacag
    47641 aaggagcaca aatcaaaaat cgtattgctt ataatctcgc agtcgtttta caagaaagtc
    47701 aagagacgat agaaccggat ctgaaacttt tatcaggaga tttggacgag gtcaacgcaa
    47761 agccaactgt tcagcttcgt ttccaaaatc ctcagcctag gattatcagc aatttgatat
    47821 ttacgagcaa gatcttttat gaaaatcagc tttatattga aaatacgtct aatgaatttt
    47881 tagttgcacc aaattcgaat tttcacttga atcttgattt agctggtgat aaagcaaaag
    47941 ccggcgatta ccgcgcagaa atcatagcaa aatcaggcga cagtaatgaa tggcgattta
    48001 cacaaaactt tacgatcaaa aaagaaaaag cacaaaaagt aaatgaaaat tccgtttttg
    48061 cagtacaaga acaatctttc ccatggcttt atgcaggatt ggttgctgca gttctagtgt
    48121 tatggttgat tttgctgttt ttgtgggtcc acaagaaaaa gaaaaaagga gaaacaacat
    48181 gatgaggtga tttcgttgaa aacatcgatc ttattgggag ggattattgc aagtttgctg
    48241 ttcttcagct ggcaagagcc agtccaagca gataccaaaa gttcaggtac gattacattt
    48301 tatgatctaa gtccagttcc gcatccaagt ggttcagtca atggcgcatc aaaatagcag
    48361 acacagctac cgatttataa agaatctaat caacatggcg tattcccgga gacgaatgaa
    48421 gaaaagatcc gttttcttta tttgatcatt ggtatagaat tatggcttct tgcgtggttg
    48481 ttgttatgga gaagaaagga aaaggaggat gaacatgttg ctacaaaata aattttcatt
    48541 ttttcgctcc ttctttttta cttcgctttt tgttttaagt atatttatct tttcaccttc
    48601 ggcagaagct gttggagcaa cgcctcctgc catttcttat gatccataca cgtatgaaaa
    48661 tatcgtacct ccaaatggtg gacgtagtgc agtcaatggc gggaagcttg tccaactaac
    48721 tggggctaac caattgccta aattgactgc tacttatttg aacgatggtt caaatgatcc
    48781 ttggaaaggt ggcacggtcc gttttcattg ggaaagccat gtgaaactaa caaatgtact
    48841 tgatttggtg aatatcactg cacaaggatt tgcatttgtg gcgatcatca atttgccgga
    48901 acatgtatca agcagtgatg tattaaaagc aattgactgg aacaacgcct acttgtatat
    48961 tgccggtgcc cccatcaagg ttactagcgg tagtttatta tcagcaggaa gccatacctt
    49021 gcgttttggg atggggtcgt gggatacaaa tactctattg gcagatatta ttgctattat
    49081 tacgcgaggc gaattcaacg tggacgatat cccgcttcaa tttgatgtta cagctaatgt
    49141 cgcgaagatg acagaaaacg gagataaata tgatacgagt ccaaacaaaa ttttgaccaa
    49201 gggtaaatta caaccttcta tgtctaaaaa ggccgttttt tctgttgatt tttatgattc
    49261 gaataatatt atccaagatc gtatgttcaa ttcgatttta gctccagctg caggtagatt
    49321 ttatcctaaa ttaactggcg gaaacttgaa tccaggagca tatgcatttt ctgcaagtgc
    49381 agagataaat acgtggaata gttacatctc aacaagtgat tcaacaggaa aatataatac
    49441 atttgctgat accacagaat acgtggatgg aaataaccag aaccttccag gctctaccaa
    49501 tagtcggaca ttgacgatgg ggctgactga aggacgtttt gatcagttgc catttagtcg
    49561 ctttgatcgc gtagtcaact attttacagg aaaaaacgtt acacaaggag caatactgac
    49621 tcatactcca gcaagcacaa gtggattgaa tcagacagcc aatatcgtgt acagtgggaa
    49681 agatgcgcaa ggcggattgc tttctcctgt tgctttaaag gtattggagc agtacaagct
    49741 agacggaacg gttttaccaa caaacttaac agccgatagt cagtggggaa agctcctttc
    49801 ttctgcatcg taccaagtca cggccaattg gtcagcaact gaactaaaaa agggttcgat
    49861 ccattacagg ctttattcga aaggaaccca aaaattagcg acaggatgga cagatcaact
    49921 tttccaaacg atccaatcaa ataacggggg tgtaaataca gctacttcta cactacctgc
    49981 attggcttca gggcaatatt attttgatta tcgcttggtg gacgatgtac ttactaacat
    50041 gtatccgtct tttgcgtaca aatggcagtc tgaacaagct ggaatcacca ctcttcctca
    50101 aataacagtg gctaattttc catctgtgag tgcagatagt cagctaaaaa accttagcag
    50161 acaacctgag acaggagatc ccctgtctgc tctatcagga gatacgattc aagaaaatgt
    50221 gacattcacg ttaacaaaat ctggggatgc gataaccgac aaaaaaatca cgatctcact
    50281 tcctgaaaat actacttata tcaatggttc cttaaaatta aatggtacaa ctatcgcaga
    50341 taccggcatt caacaaggag tttctgtccc agcagatcta ttgagcaaaa taggagatac
    50401 cattcatctt acttacaact atcaattaaa tactgtagat acttctgtac aatccgtcag
    50461 catactgaca aaggcagctg tactttccag caatattaca ttagcagatg gtgctaagct
    50521 tcctaaccca gttgtccaaa catctgctaa aacaattctt gtccccaaac aagaattaac
    50581 attagttaat gtaccagatg attttacatt tggtaacgat ctccccaaac cgttgaagac
    50641 aagttattat gaagcaaaag gcgatttttc ttttgatgtg cgggatactc ggcttccaag
    50701 cacgtctcct tggcaactga cagggacatt gacttcttta tttaagaatg atcaaggtca
    50761 agaattaagc ggaacaaaat tatacttcaa tcattctgga tcaaaacaat tgattcagca
    50821 aggtcaaaac acgttgattt atgagagtga tggaacagct aaaggagagg ttctcgttga
    50881 ctttcccgat accgatggtt tactcttaga ggtaaatagc agtacgaatg ctcaacctgg
    50941 cgcaacgtat caaggcatgg tcacatggga actgacagct gggccaacca gctaagtgat
    51001 tagaatttgt atggatctgt gataactgtc acagatcctc tttttcaagg atgagaagga
    51061 aacttctgct gttaaaatca gaaatgcttg gaggagtgga cttggaactt ttcagtttgc
    51121 ttgaaaaaaa tgaacaacgg caaatcaaac ttttccaact tttattagag gaaaaaggag
    51181 agatttccgt taataacgta cttacccgct tatcagttga tcgggctacc ttgaaagaag
    51241 atctgtttta tttacaagct aacttggaaa atatcaaaca attggaaatt gttatccaag
    51301 aagggaatat tttattaatc agacatggaa atatagcagc agtcgatgtt tattatcatt
    51361 gctacttgcg ctattctaca aaatatcaga tacttcttta tctgttggaa aatggctcat
    51421 ttgatcggca gaaacttgtc atggaactta atatcagttc ggctactttg tctcgcagag
    51481 tgaaggaatt aaatgattct ttaaatgagt ttcatctgaa aataaaaagc gggcggctga
    51541 ccggtccaga aagtcaaatt tgttattttt atttccaatt attttggttt ggacgtcctt
    51601 atcttgaaaa caaaaaagaa tacagtgatt tatcaggaaa cactttttta gatctgctgc
    51661 aaaaagagtt tagttttact attacagaag aaggacgatt gaaatttgaa atatggcttt
    51721 ccattatgaa gaagcgaatg cgctgtacga aaaaatccaa accagattat agcaatcttc
    51781 ctgttggatt gtttcaaacg acacaatttt tattggacct ccatacattt ttgacccgtt
    51841 acttctttca atatgccttt ccttggaatc aaaatgaaac gttggttttt tatcttttca
    51901 tgatcagtaa ctttacatta gatacacata actcgcatgt ccaggagttt ttgataagcg
    51961 aaaaatacaa agacgacgta gtagctcaat tgaatcgaac gtttaaacaa tcgatagaag
    52021 aatatttctc tttttatgtt tttccagaag agatttcgca aaagattgcg ttgacagtga
    52081 tgcaaaatca cgctcatttt gcctatttta gaggatggat gaatattttt ggccaagaag
    52141 gattaaaaca gcggttaact gaagtagaag ataaacaatt cctggtttta tgtgaaagat
    52201 tggtcagaca aacatttgct attgttgatt ttactgaagt agacgaggaa aatgcccgct
    52261 ttgaattatt tgctcgctat gcatctattt tgcggacgct gatcaagcag ttagaattac
    52321 gtctgcaaat tgcttatgat cttccttatg aaaggctaat ggcggatatc gtgaaagaaa
    52381 tcatccagga acaattgctg aatacgatca aatatgattt agtcgaatac gagaaagaaa
    52441 agcagtatga tatcattttg actagccaat tgaaagagta cccgtcacag aagtccgcta
    52501 aagtttttgt attcactagc aacgaatata attatgattt cccctatttg aaccaatttt
    52561 taaaagaatg ttatttagaa aaattgaatt taaggatgaa taaaacatga aaatcgtgat
    52621 cattggtgct tcccatgcag gcatcacagc tgccctaaat ctaagaaaac ttcaaccgaa
    52681 agcagaagtt ttactgatcg atgaagatca taaagatgga ctaggctatg tttcaaatgg
    52741 aatcaacctt tatttaaaag gaaagatacg tagtttagct gaagttgccc ataacatgcg
    52801 gactcttcaa gaaagtgggg caaaactgat caccgaatgg agagtaactg aacttgatcc
    52861 agacaaacat cagctcatcc tcgcatccaa agaaggaaaa aacgagacca taacctatga
    52921 taaattaatc gtagcaacag gttcctctcc tgtcaccttg tataaacaaa ttgaagctga
    52981 aaatgtctac acctataaaa atctagtgca atctaagcaa gtacttgccg ctttaaaaga
    53041 agcaaaagaa gtagtgatct tcggtgctgg ttatattgga ttggaattag cagatgcttt
    53101 gagaaataaa ggatacatta ttcatctagt tgattatatg ccgaatgttt tatcaagata
    53161 tttcgataag gatatgatca acagttttca aaatcagctg caaactaagc aaatcaattt
    53221 ttatccaaat gaattcttga tcgattggaa aaaatcagaa gagaaagtag tatccgtaca
    53281 acttctatct caagcaataa aggcagatat ggtcattttt tctgcccaaa ctcgtcctaa
    53341 tacgacattg ttaaaagaaa aagtggcttt gtatgaggat gagactgtga tagtcaatga
    53401 atatctgcag acaagtgatc cggacatcta tgcgattgga gatatcgtcc cagtcagttt
    53461 tgacaaaaat aaacggcatc tctttttacc tttagttact cgagctgtac atatggcaag
    53521 agcagtagcg ctaactttga gtggtcagcc aaccgcttac gacctcagac aaaagataac
    53581 agcagcagtc attatagact actttttagg aactgtaggg ctgacagaag atgaagcgcc
    53641 attcttggaa caaaataccg gttcgtgttc aggagaattt gatctatttc cacaatacga
    53701 tgaagaaaac aaaacagtaa atgcaaagct gatctaccat ccggatacat tagaaataat
    53761 tggcggacag ctgataagcc aagaattctt attatcagat ttgaacctgc ttgcggatat
    53821 cgtgaaacac aaaactacga ttccacagct agcagttgag gattttggat ttctgtctga
    53881 acacacctct cgttttcact acctcaatga gttagctttt aaagtactag ctaagagagc
    53941 aaatagcaat agagtagata aaagactgtg agaaatatca cggtctttta ttgtgtgggg
    54001 atataataaa tattaatcaa tcgagaataa aaaattcata taatgaaata gcggaagaat
    54061 tttttgagca taatattcgc caaaaattta tcaagtgata aaattgttgt ataaaatgat
    54121 tatttcagga ggaggagtta aatgttttta gcattaaatg aaattatgca ttcaaagtta
    54181 cgttatgcgt tagttgcagg ggtgatgttt ttgatcgcct acctggtatt ttttttgact
    54241 gggttagctt atggcttagc tcaagataat cgaacagcag tcgacaagtg ggaggcagat
    54301 tcgattgtgc tttcgaaaga tgcaaattca aatctaggga tgtccatgat tactaagaag
    54361 atagcagaag aagtcgaagg tgggaaagtg gcgtatcttg cccagacacc tggagtcgtg
    54421 actagtaaag acagtacaga agaaggaaaa atcaatgtta gcttcttcgg tatcgataaa
    54481 aatcaattca tcatgcccaa tcttgttgaa ggaaaagctt ttgataacga tgatgaggca
    54541 gtaggcgata ttagtttgaa agaagaatat ggtctagccg taggagatac agttaagtta
    54601 tctggtagtg acaagacgtt taaactaact ggctttacgg atcatgccaa attcaatgtc
    54661 tcaccagttc tctatacaac catcaatgct taccaagaga tccgcttcga aaaagaagat
    54721 acaagtgaaa atgcacggat taacgcaata gttgtcagag gtaaaatcag taatttacct
    54781 gaagatttag aacagatcaa aatttctaaa ttcatcaatg aattacctgg atataatgcg
    54841 caagtattga cttttggatt tatgatcgga tttttgatcg ttattgcggc tattgtgatc
    54901 gggattttca tttatgtact gacgatgcaa aagattaata tctttggtgt aatgaaagca
    54961 caagggatca caggaggatt tattgcgcgt tctgtagtgg cacaaacatt cattttatca
    55021 tttgttggta ttcttcttgg tctattagga acagtgggaa catcccttgt tctacctgat
    55081 gcggttccat tccaaagcaa ttggctgttt tttggcgtca ttagcttgtt gatgctggta
    55141 gtagctgtgt taggcgcact attttctgtt cggacaatcg taaaaatcga tccgttgaag
    55201 gcaattggat aagaaggagg aagagcatga aagcaataga atttaaagaa gtagaaaaaa
    55261 gtttccaaga tggcgaccaa gtagttaaag cattgaaaga aacaaccatg agtatcgata
    55321 aaggggaatt tgttgcaatc atcggtcctt ctggttcagg taaaagtact tttttgactt
    55381 tggcaggcgg attgcagacg cctagcagtg gctctgtatt tatcaatgat caagaattca
    55441 gtaatcaaaa agaaagtgaa cgcgttaaac tacgttttaa agaaattggc tttattttgc
    55501 aagcttccaa tctggttcct tttctgacag taaaaaagca gttattatta gtagataaga
    55561 tcaaacatga acatcgtcaa aaagaagcaa aagaattatt tgagcagctt ggcgtggata
    55621 agttgatcaa caagtatcca gaagaactat ctggtggaga acggcaaagg gtcgcaatcg
    55681 ctcgtgcatt gtacaatgat ccgtccatta ttctagcaga tgaaccaact gctagtttgg
    55741 attcagaaaa ggcacgagaa gtagtcgata tcttggcaaa agaatcaaaa gacaaaaata
    55801 aagcaacgat catggttact cacgatacac ggctgattga caaatgcgat agaatattta
    55861 tgatggaaga tggtgtattg aaagaaaaag aataaccaaa aagcaggtgg aaaaatggtc
    55921 catcgataca acaaagatac acagcaaaaa attttgaaag aagcgactga cttgtttatg
    55981 tccaagggat atctcggcac ttcaacaaga gagatcgcac aaaaagttgg gatcacccaa
    56041 cccaatctct atcattattt cggtgataaa gaaaaactat atacggcagt tttagaaaac
    56101 cacttaaaag atgttggaaa agctttgaga gaaatcgttc aaacaagcga aacgggattt
    56161 caagtaacct tgacaaaaat ggcgcagttt ttgattgaga cacatctggt cgatttgttt
    56221 ctgatgcttc acgatcttga aagcaatctt tcaaaggaaa caagagatca tcttttcttt
    56281 ctatggaaga aaaattatcg tgaacctttt gaagaaatct tttcagcaaa ccaatctgtg
    56341 ctaagaaatg ggatttcaaa agaaatcgca gcaaggcatt ttttcttagt gttagcacct
    56401 tacatcactc ggtcgaaaag acctgtggaa gaaccgctaa atgtggcgca attgatcgat
    56461 ttatatttga atggtgtatt aggagaagcg taaagctgtt atatagggag aaaaatagtt
    56521 aggtgaagaa gcaagatatg acgaagatcg ttatatcttg ttttttttat ataggtagtt
    56581 tttcataaat acaaatttgt tattctctca tgattatcag ggtatatttt tatttattat
    56641 gtcggtgttc caggaagtgt tttaatttaa taacgaagaa attaattgtt tgtagaatga
    56701 aggaaactat ttattgggta gatgaatcac cacgaatagt caaaaggaga tttcaggata
    56761 tgccaaaaat gaaaaaaatc attttagcag taatgttatt ttctacggtt atatctttta
    56821 cagccccttt tttgcgtact taagctgatt ttaagttttg acccttagtc tggatctacg
    56881 aggtgagagt caagaatgaa aaaaataatt ggagcttttg tatttgcaat cattatcatt
    56941 attatctgtt ttcaaataga tgtttttggt caaaaaaaga tagttggaca aacggtcagc
    57001 agtacgaaca gtacggttac aaagacaaag gaatcatttg atgatacaga acaagagaca
    57061 ttaatcaaaa tcggaaaaaa tgaccgtaca ctatatacag atgactcgct aactacccca
    57121 cttgcaacta taaacggcgg agagctggcg gagtttcttt ctgaaacaaa aaatgcttat
    57181 cagatcaaga caaatgatgg ctatactgga tatttagccc tcgaagatgg aaccaaagtc
    57241 acaaagaata tacaaacaaa accggaagag ctatctgatg cagtgattgt attagatcct
    57301 gggcatggcg gaaatgatac tggggcatta agcaatgatg aacaaacaga agaaaaagat
    57361 ataacattaa gtacagccat aaaagtaaaa aaggcgctag aggatgctgg agcaacggtt
    57421 tatttgaccc atactacaga tgaattagta cagcttggag atatatgcga ctacagtgaa
    57481 gaaaaaaagg cagatgtctt tatcagttta cacgcagact ctacggaata tgcgaatgaa
    57541 gcaactggaa tcacgacata ttattactat ggacaagagg aaacattagc acagacaatt
    57601 gctgactcct tcactgatct gcctctggat tcaagaggaa tctccactgg gaactatcaa
    57661 gttcttcgag aaaatcttca accttctatt ttaatcgaga tgggttatat gaataatgat
    57721 agtgatttaa aggaattagt aacagacagt tatcagcagc agattgctgc aagtttgaca
    57781 caagcattga ccacttattt tcagtaataa ataagcccag ccaaacaaaa atagctcctc
    57841 atatttttcg tttggccggg cttattatcg cagatgcaag cttttgaaca ccgtttaagg
    57901 aagaggttgt gagcctgccg tttaactccg cgtcacaagg agcaatttca aaaaacagct
    57961 tctcatgttt gatgactatt gtgacttgtg accgaggagt tggcatgaga acaccgttta
    58021 ttcggaacaa gggactgtga catgactttt gtcacagttc cattattttt ttagcagctt
    58081 caaagctttt tctgtattgg caaaatgaag tttggcatat ttttcaagca taggcatgcc
    58141 gcctttctcc aatagttttg ccgctacttg gtcagatttc gttccagctc ctgatggaag
    58201 ggtgattcca gcttcagctg atgctttgtg taactcttcc aaaaagctgg cacgactgat
    58261 gatagaagca gcagcaacag ctaaatgata ttgttctcct ttagtaacga agtacagttt
    58321 ttcttgtaat tgattttttt ctaaacgcgc atatttttta aaatttgctt ccggcgtaaa
    58381 ctgatcgatc aaaatcgctt ctggtttttc tggctcgatt ttttttagca gcaaatggat
    58441 cgcttgattg tgcaaagcga ctttcatccg aacggcattg tattttggtt ggatctcatt
    58501 gtatttttct ggagataaga caagcagttt ataggggatg gtttttttta agatgtcagc
    58561 aagctggatg atttggctat cttttaactc ttttgaatct ctaacaccaa gtttacgtaa
    58621 ttctgcaagc tgatcacgtt tcacataagc agcacatact gttagcggac caaaatagct
    58681 gccatttccg acctcatcac tacctaaaac ggataattga ctgatatttt ttggcaaaga
    58741 agaggctgtt tttgctggct tggcttgttt atcctgtgcc tccccccatt tatcagcttc
    58801 tattgctgca ttcgtacctt gaaacatcac ttttccggat gtataagcgg taatggtcgt
    58861 cccgtctttt tttgcagcaa agctagtata aggaatctgt ttatttaaca aataagagcg
    58921 atagtatgct ttcatttgac taagttggtc gtttgttgct ttgataatga cgttgctcat
    58981 aaaattctcc tcgtttttat acataaaact ataccgcaac tcacgacttt tcgttttcta
    59041 agagattgcg agacatagca tttttttaaa gtttatcata taatagttaa gtatgtgaaa
    59101 aatatttgtg gagaacggtg aaagaaccaa cttcatggta cactaaataa aactttcatc
    59161 aaataggagg aaatgattcg tatggcgcac gaaaaaacac gctacaaagc agtgattgcc
    59221 aaccaaacat atactattat cggacgggaa accaagcatc atatggatat cgtaacgaag
    59281 ctgatcaatg aacagttagc agaattgaaa caattatcac cacaaatgga taatgaacaa
    59341 gcagcaatct tgatggctgt caatgcgctt tcggatcaat tgaagaaaca agaaagaatc
    59401 ttggagctgg aagaagaaac agcagaatta aagaaaaaaa tgatcaaatt tacagagctt
    59461 gaaaatcgtg tgaaacgcat tgaagcaatc gagaacgaag ctcgggaagt attgaaagaa
    59521 aatggtcaag cagatcatac cattaaaaat catgtggaag cacaacagat tttaaacgag
    59581 aaacgaaaag gacaaattaa acaaaaatct tctaattaag atccttttat caaaataaga
    59641 aaaatttaaa aaagttagaa gagaaaggaa cgtagcatgc tgagtttgct gattttattt
    59701 ttattgctaa ttgcgttttt ttctggagca cgtcgcgggt ttgctttgca aatcatattc
    59761 gcgattggat atgtattgtc atttattgct gcccagcatt tttacaaacc attagcaagt
    59821 catttggaat tatacattcc atacccagct gtcaccccaa catcaaagtt agcatttttt
    59881 gatcaggtat ttgcttttca cctagatgaa gctttttatg caggaactgc ttttctgatt
    59941 attttgctaa ttggctggct gcttacccga tttgtggggg tttttgtcca tggattgacg
    60001 tatgtgccga tcttgagaca ggtagactgg attgcaggag gcatcctgtc actaatcatg
    60061 gcttacgtta ctatattttt gattttgcag ttacttgcct ttgttccatt agatgtggtc
    60121 caaaatcaat tcggcgagca tagtttcgct cgttttatcg ttgagagaac gccatttctt
    60181 accaacaaga tgtatgagct ttgggtaacg aatattttga attaaggaaa atagtgctgg
    60241 aaaatatttc gttttttgta cagagtagtt tatttaagaa ggctgcgtag cgtatgtccg
    60301 gcacagctct tttttcatag tgaaagataa ggtgataaaa tgaataaccg aatccttgaa
    60361 acattggaat ttgaaaaagt caaacagatg gtcagacaat ttgtagtgac tgcacaagga
    60421 aaagaagaac tggcagaatt ggtaccagtg agtgagaaac aaacgatcac aaactggctt
    60481 caagaaactg aggatggatt gaaagtgcaa cgtctgcgag gcgggatccc tatacctaaa
    60541 cttgaaaata tccgtcccca tatgaaacgg atcgagatcg gagcagactt gaatggagtg
    60601 gagcttgcac aagtttccag agtattgtct acgacaagcg aattgaatcg tttcattgat
    60661 gatctttctg acagtgaaat cgaatttgca cgtttgtata tgtgggcaga tcagttagtc
    60721 acgatccctg ttttgagccg ccgtttaaag gaagcaatcg atgaagacgg acgcgtgact
    60781 gatgacgctt ctcctgagtt aaagagcata agacagaaca ttcggcgaag tgaacaagct
    60841 gttcgtgaac agttagatgg gatcgtccgt gggaaaaatg caaagtattt aagtgatgcg
    60901 atcatcacca tgcgaaatga ccgctacgtt atcccagtca aacaagaata ccgcggtgta
    60961 tttggcggtg tagtccacga tcaaagtgct tcaggacaga ctttatttat tgaaccaaaa
    61021 caagtggtgg atttgaataa tcgtttgcgt caataccaaa tcgctgaacg aaatgagatt
    61081 caacgtattt taagtgaact ttctgctgaa cttgttcccc atcgtcaaga aatcatccac
    61141 aatgcttatg tgattggtaa aatggatctg atgaatgcaa aagcacgatt tggtaaagaa
    61201 gtaaaagcca tcgtgccggg aatcagtgaa gacaatcatg tcgtcttgaa acaagcaaga
    61261 catccactga tcgatcagga aaaagtagtt tctaatgaca tcacaatcgg aaaagactat
    61321 caagccatcg tcattacagg acctaacaca ggtgggaaaa cgatcacgtt gaagacttta
    61381 ggtctgttac aactgatggg gcaagcagga ttaccgattc ctgcaggtga agaaagtcaa
    61441 atcggtattt ttgaggaagt atttgcggat ataggagacg aacagtcgat tgagcaaagt
    61501 ctatcgacct tttcttctca tatgacgaac actgtagata ttttatcaaa agtcaatgaa
    61561 aaaagtctgg tattatttga cgagctcggt gcaggaacag atccgcaaga aggtgctgct
    61621 ctagcaatcg caatcttaga tgatcttggt aaaaagtctg cttatgtgat ggcaacaacg
    61681 cattatcctg aattgaaagt ttatggatac aatcgggcaa atacgattaa tgccagcatg
    61741 gagttcgatg tggatacact aagtccaacg tatcgtttgc tgattggcgt tcctggacga
    61801 agcaatgcgt ttgaaatctc tagccgatta ggtcttgata cagaagttat tgatgaagcg
    61861 aagcagttga tgaatgatga gagccaagat ttaaacgaaa tgatcacaga tttagagaat
    61921 cgccggaaaa tggcagagac cgaatatctg gaaatgcgtc attttgtttc tgaggcacaa
    61981 gaacttcacg atgatttgaa agaagcttac agctatttct ttgaagaacg tgaaaaagaa
    62041 atggaaaaag caaagaaaaa agcaaacgaa gtcgtgtcag aggcggaaga aaaagcagaa
    62101 aaaataattg ctgatattcg taaaatgcaa cagcagattg ggcaaggaaa tgtgaaagag
    62161 catcagttga tcgatgcaaa gacccaatta gcaaatctac atcaagaaga aactttgaag
    62221 aaaaataaag tattgaagaa ggcgaaagaa caaaaaacgt tgaaaccggg agacgaagtg
    62281 ttggttacga cttacggcca aagagggacg cttttacgta aaaacgggaa tcagtggcaa
    62341 gtagaaatcg gtatattaaa aatgaatgtg tccgaagacg agctgacgcc tgttgctcct
    62401 caaaaagagc cgacacaacg agttatccat gctgtacgat ctgaatctag tagtcacgtg
    62461 ccgaatcaat tggaccttcg aggaaaacga tacgaagaag cgctaagtga ggtagatcaa
    62521 tatttggatt ctgccattct agctggttat cctcaagtga ctattgtcca cggaaaagga
    62581 acaggcgcac ttcgcaaggg aattactgat tatcttaaaa accatcggag cgtcaaaagc
    62641 tttgagtttg caccggcaaa ccaaggcgga aatggtgcga caattgttaa atttaagtaa
    62701 agcttactaa aggtaagcag atggttcgct atccaagtat agaaatgcta tactaatcat
    62761 agattttaaa aatggaggtc tttgatatgt cacaagtaat tacagataag acatttaatg
    62821 aagaaacaga taaaggactt gtattgattg atttttgggc aacttggtgt ggtccatgtc
    62881 gtatgcaagc accgattttg gatcagttgg aacaagaata tgatgaagaa gaattcagaa
    62941 ttgctaaaat ggatgtggat gaaaatccag aaactcctca acaattcggt atcatgagca
    63001 ttccaacatt aatgttgaaa aaagatggtc aagtagtaga aaaagctgtt ggtgttcatt
    63061 caaaagaaca actacgtcaa atgatcgatc aatatttata aaaacttaca gcaaaaataa
    63121 gctgagggtg ggactgaatc cagttccgtc ctcggttttt ttgcggttga gttaaggtta
    63181 ttcaaattaa tattttttga gtataattac gttgtcaggc tggattgttt ttttgacaga
    63241 catgctataa taactttaat tgaatatgaa ggggagtacc agatgaacga acgaatcaaa
    63301 aacaaattag ctttacttcc tgatcagccc ggctgttact tgatgaaaga taaaaatgga
    63361 acgatcattt atgtcggcaa agccaaaata ttaaaaaatc gtgtccgctc atattttact
    63421 ggcagccata atacgaaaac ggaacggctt gttagtgaaa tcgaagactt tgaatacatc
    63481 gttacagaat cgaatatcga agcattgctc ttagagatca atctgataaa gaaaaatgat
    63541 cctaaataca acattatgtt aaaggatgat aaaacctatc ctttccttaa gataacgaat
    63601 gaaaaatatc cccgtttggt gattactcgt aaagtactaa aagacaaagc actgtatttt
    63661 ggaccatatc ccgatgtcgg tgcggcgaat gagacaaaga agatcctcga tcgattattt
    63721 cctctgagaa aatgcaaacc tagtcagacg aaggagcctt gtctttacta tcatttggga
    63781 caatgtctgt gtccttatta tttcgacgta gatccgaaag tctatacgaa aatcgttgat
    63841 gaagtgaaaa agtttttaaa cggaggacac gaaaaaatcg agtcagagat ccatcagaaa
    63901 atggaaaaag ctgctgaaaa catggagttt gaaaaagctg cagaataccg agaccagatc
    63961 cgtgccattg agacaatcat gactcgccaa aaaatgacaa atactgattt actggatcga
    64021 gatgtatttg gttatgcgat tgacaaagga tggatgtgtg tccaagtgtt tttcgtaaga
    64081 caaggaaagc taattgaacg agatgtttca atgtttcctt tctataacga agcagaagaa
    64141 gatttcttga cttacctcgg tcagttttat caggaaaatg agcatttcat tcctaaagaa
    64201 gtcttgattc ctgatacgat cgacaagccc agtgtagaag ctttgttagc tacgaaagtg
    64261 ctgcaaccaa aacgaggaga aaagaaaaaa ttagttgaat tggcgaataa gaatgcctca
    64321 gttgctttga atgaacggtt tgatctgatt gccagaaaac aggaacggac gatcggagca
    64381 gttgaacgtt taggaaacgc gatgaatatc ccgaccccaa tacgtatcga gtcttttgat
    64441 aactctaata tcatggggac gaatcctgtg gctgcgatgg tcgtattcat tgatggaaaa
    64501 ccggcaagaa aagaatatcg gaaatataaa ataaaaacag tcaacggacc ggatgattat
    64561 gcatcaatga gagaagtcat ctatcgcaga tattcacgag tgattcgcga agggttgcct
    64621 ttacctgatt tgatcttgat cgatggagga aaaggacaag tagatgtggc aaaagatgtc
    64681 ttagaaaatc aattaggaat cgatattcct attgctggca tggcaaaaaa cgataaacat
    64741 aaaacaaatg agttgctatt cggtatagat ttggctgtag taccgcttga gcgaaattca
    64801 ccagagtttt tcttactcca gcgaatccaa gatgaagtcc atcgattcgc aatcactttc
    64861 catcggcagc tacgcagtaa aaacagtttt gcttcccgat tagatgaaat tgaagggtta
    64921 ggaccaaaac gaaaaaaaat gctgcttaaa gagttcaaat cgttgaaaaa tatcacagca
    64981 gccacgacag aagaattaca agaaatcgga ctgccgaaaa atgtcgcaca aaacgtattt
    65041 gataaattac atcaggaatg aggaaagggc actttacaaa gaaagtaaag tgtcctatca
    65101 ttttatgtac aacaaaaaga gcgtttacgt tttgttggta aataataaat cgcttacgtc
    65161 tggtgtctaa ggatatatgt gatttcttga agaaggagtg aagaaatgtt agaagtcaag
    65221 gatcttgtta aaacttttgg gaactacaca gctgtcgatc atgtctcttt ccaaatcccc
    65281 gatggaaaaa tcatggggct aattggccaa aacggggctg ggaagacaac gacttttcgt
    65341 ttgatcttgg attttttgac acaagaccaa ggagaagtgt tatggaatgg ccatcatctt
    65401 ggggagaaag attatgatgt catcggttat cttccggagg aacggggact ttatccgaaa
    65461 gtaacgattc aagaccaact gctttatttt gcagaactta gagggaaatc aagaaaagag
    65521 attgaaccaa aaatcgattt ttggatggaa aaatttcagg taaaagggaa aaagacggat
    65581 aaagtaaaat ctttgtctaa aggaaatcag caaaaagtcc agctgatcgc cacgttaatc
    65641 catgaaccta aattgatcat tttggatgag ccattcagcg ggttagatcc ggtaaatgct
    65701 gaattgctaa aagatggaat attggaattg aaaaaacatg gttcatgtgt cattttttct
    65761 agccacaata tggataatgt agaaaaaatc tgcgatcatt tgatcatgtt gcgaaacgga
    65821 aaaatggttt tgaatggaaa agtacatgag attcgtgaat catttggccg tacgaagtta
    65881 ttcttggaat ctggtttaag ccaacaggaa gtagaagaaa tcgaaggcgt gaaaaaagtg
    65941 atccttcatg aagacaatac gttagagatt accttagaag atcctgaagc tgggaaagaa
    66001 atctttactc gtgcgactca gttcggctac attcctatgt ttaaccagca accgccaact
    66061 ttggaagaga ttttcaaatt gaaagcaggt gaaatcgatg cgtaagtttt ggattattac
    66121 caaagatgtc tatttaaaaa atgttaagtc gatttctttc ttgatcatga tattagtccc
    66181 ttttatcatg ctgggtatca tttatgtagc aggaaacttt gctcaacaaa atagtgatgt
    66241 caataaaatc ggcgtattgg ctgataatga gcaaatcagt cagcaaatga gccaagtcaa
    66301 aacagatgat tttgagttca aagcagttga ttctgaagaa aaagcacaaa aagagctttc
    66361 ggaagaaaaa atcgatgcgt atttagtagt ctcaactgag aatgataaga taaatgggat
    66421 gctttatagc gaaaattcat taggacaaag tacacaacta ctgatacaac aacaactgac
    66481 tggcttgcaa tcgatgcttc gagcaagtca attaggcatt tcaccagaag aagtagctag
    66541 cttgagccaa caagcaagtt tgactcgaca aaaagtcaat tttgattcaa aaggaaaaat
    66601 gacagttgga gaagataact cgacagtcca atatgtcgta agttatgtag caacgattgt
    66661 cttgttcatt attattttga cgtatgcgca gatcattgca caagagatcg cttctgaaaa
    66721 aggcacgcgg atcatggaag tgatcctgtc cagtacgact gcacaaaagc atttttacgg
    66781 aaaactaaca ggtgttttac ttgttgcatt aacgcaaatg gcattatacg gtattatttt
    66841 tggtatagga tacagtcaat tcaaagatat ggaaatggtc aaaaatatat tagacggtat
    66901 ctcattggat aacttgattg gaccattctt gtggtattct cttctattca tgatctttgg
    66961 cattttgatt ttttctgttt tagcagcttt atgtggctct ttggtcaaca aagcagaaga
    67021 tacagcaaaa gcaattttgc cagtgactta tctatctcta ggcggatata tgcttggatt
    67081 gatactagga gcttcagatc caaacaatat cgttattcgg atcacttcgt atattccatt
    67141 cttatcttca tatattatgc cggttcgctt agcaaatgag acagtcggta tgggtggagc
    67201 attgatttcc ttgttggtac ttgtagccgt aacattctta ttgatgatct tgtctgcaaa
    67261 catgtacaaa tcgaatgtac tcgtgtatag cgaaggcgga ttatggagtt cattgaaaca
    67321 atcgatttca attatgagaa atgaacgaaa aaaagcataa aatatagaaa aatatagaag
    67381 gaagctggac atttattgtt cccagcttct tttttgtata gacctatttc tattttttta
    67441 ttatattgga tatatatatt cattgaaaat agagcataac aactttataa tgttgagtat
    67501 accaattttt ggaggcgttt taatggaccg ctatttagat ttactttcag agaagttccc
    67561 tacaacggaa gatgtcatca cggaaatcat caatctcgaa gcaattttgc agcttccaaa
    67621 aggaacagag ttatttttga gcgatataca tggcgaattt cctgcttttg atcatattct
    67681 gcgtatcggt tcaggaaatc ttaaagaaaa gatcaaagac cttttctctg aacaaatgac
    67741 ggaaacggag atcagccaat tcactatttt tacggcttat ccagaatatg tgttgacgac
    67801 tgattggtac aaaaaacaag ataaatccca gctgatccat cgtttgatcg atcttttacg
    67861 gtttacgaca gtcaaataca ctcgatcaaa agttcgaaaa ggattgccga aagaatatag
    67921 ctatatcatt gaggaactct tgtatatcga tgatcgtatc aacgggaaaa aagactatgt
    67981 aaaaaaaatc attgaacaac ttgtcttgat gaaggaagaa gaaaaatttt taacaaaact
    68041 tgcgcagacg atccaaaaat ctgtcatcga tcatttgcat atcgtgggtg atatttttga
    68101 tcgaggaact caagcagcca aagtaatgga tcgaatcatg gatttttcct ctgtagatat
    68161 ccagtggggg aatcatgata ttttgtggat tggtgcgtat tgcggctctg aggcatgttt
    68221 attgacgctt ttacggattg ccgcacgcta caactattta tttgaattag agaaagaata
    68281 tggattaaat ttacgtccat tattttcttt tgcccatcaa acctatcaga agaatccagt
    68341 atttacccct aaaaacagga aagatctatc tgaaagagag caagaagaat tagaaaagat
    68401 ccatcaagca ctttctatcc tccaattcaa atcagaacat cagttgttga atcgacgacc
    68461 tgaatttaaa atggacgatc gtaaattgtt ggaaaaaatc aactatgagg aatcaacgat
    68521 cgttttagaa ggtcagctct atgagttgaa agggacttgt tttcaaacga tccagccaga
    68581 tgatcctaaa aaattcttgg aagaggaaca aaaagtgatc gatagtttga tgtattcatt
    68641 ccagcactcg ttaagaatgc aaaaacacat gacgtttttg atcgaaaaag ggggaatgta
    68701 tctcacgaac aatcagcatg tactgttcca tggctgtata cctgtagatg aaaaggggca
    68761 gctcttagca tttgaattag accaatctta tcgcggaaaa gaactgctgg gattttttga
    68821 aaaacagata actgaaagcg caaaagattt gactgcaaat gaagatttgg cgaccgattt
    68881 gatttggtat gcgtggagcg ggccattttc gcctttattc ggcaagagta aaatggcaac
    68941 ttttgagcgc tattttctca cagagcctca tacgcacgtc gaaaaaagca atccctatta
    69001 tcacttgcga gatgaagagt ggttcagtga aaaaattttg gcagaattcg atgcaaaaga
    69061 agaaggttca gcaatcatca atggacacac gccagtaaaa gtaaaaaaag gagagtcacc
    69121 gatcaaagca aacggaaaag catttgttat tgacggaggt ctatccaaag cttatcaaaa
    69181 aacaaccggg attgctggct actcattact atgcaattct tacggtttcc aaatcgtgac
    69241 acattatccg ttcttgccta ttgaacaaca atttgcaaaa aaatctgatc aaacgaatgt
    69301 aaaaaaagtg atcgagcagc agctcccacg caaacttaat cggaatacga caaaaggaat
    69361 ggaattacag caacagatta ctcaactcca aaggctgttg gattatcgaa aggacgattg
    69421 agaaaaatgc tagccaacat tgctcaatag actaaaaagc gactgcaaca aaaggcgtgt
    69481 cgcagtctcc ttcggaatta gctcaaaaaa cggtaaaata ttagaagcta tttttctgtt
    69541 tatttctcta atactcaggt cagggcgctg atttcacgac ctcttcctta aacggtgttc
    69601 tcctgccaac tcctcggtca caagtcacaa tatccaacaa acatgagaag ctgttttttg
    69661 aaattgctcc ttgtgactca gagttgaacg gcaggctcac gacctaatca gaaaaacgat
    69721 taaaattcat tcacaaagaa atcgaataaa cgctgttcag atgaatctac acgatgagaa
    69781 agttccggat gccattggac accaaggatt ttgtgcatat tatctttact ttggactgct
    69841 tcaatgagtc catcgttgga aaaggcgatg gcttttaaca aaggagaaag atctttgact
    69901 gcctgatgat gataggaatt cacaaagtat gaatcaggga gaaggtcact taataaactg
    69961 tccgaaacga ttttgacttc gtgagttgca aactgcgggg cagtgggctg ttgttcgtgt
    70021 tttacggacc attttggata taatgaaaga tcttgataaa gtgttccctc caacacgaca
    70081 ttcaatagtt gaagtcctcg gcagactgca aaaatcggtt ttctttgttt caatgcttcc
    70141 aagatcaatg cctgttcgaa ttggtctcgt tgaatatttg tttccgtcag ttttggatga
    70201 gggtcttcca tgtaaagttg cggactaaca tcctgaccgc ctgcaagaat gagtttgtcg
    70261 attttctcaa ttagttgagg cgctgaatct ggagacatga ctggcagaat aagaggtaat
    70321 ccttgagcat ctaaaactgc atccacaaat ccctgcggtg tatagcttac ttgatttcct
    70381 tggaaagtat ctgtcgctcg aatcagttga ttcccggcaa tgccgatgat tggtttcatt
    70441 tttattcccc ctaaagtaga ctaattgtaa caaggattta aaaaaattta aactatgtaa
    70501 gacttgcccc tatacttatc tgttcttgct gtgttactat ctgtaaagag aattttcgtg
    70561 tgaaattcat gacgatagtt gaaaatattg cttaatttgt tataataaaa agtaagcaga
    70621 aataaaaagg ttgggcgtaa gcttcaagga tctagttctt caaggggtga gaaggacatt
    70681 ttattgaagg ggcctgccta tactaagtta tctttagagg tacatacttt caatgaaaaa
    70741 agaaagcatg tacctctttt ttaaatcgaa aggaagtgaa gcaagtgtta gaagctttgg
    70801 aacaaatccg aaaagcagaa gaagaaaatg agaagcgtgc tcgaacccta cggcagcagt
    70861 tgaagaccta tgcagaagaa aaagagcaag aattggagat aatccaaacg aacagtcggc
    70921 aacagctgaa acagttggta gaagaaaaag aacaattcga aaagcaagaa ttagaaaaag
    70981 aaaaaatgaa attgaaagca gaagcagaca aggtgcaagc aactttgaaa gaccaatatc
    71041 aaaagcatca gagtcaagca atcggtgcaa tcattgaaag ggtgaaagaa acttatggcc
    71101 gtcactaaga tggaaaaagt gaccctcatt tcagataaaa gaaatcagga gaggatttta
    71161 caagcagtac aaggaatcca aaatgttgaa atccgggatc tgtatcaaaa tagaacaaac
    71221 aaccagtggg tagaaaaata ttttccagat accacgatta ttgataaaga agcaaaatta
    71281 agcgctttag gcaatcggct gaaagacatc caagaagcta tccaattcat acaacaccac
    71341 ggcgatagcc gtcaaaagaa actccatttg aaacgtcaag aactttcctt acaagacttg
    71401 gaagcaaatt attccgaaga aaatttcatg aataaattag aagaagtcct tgatttaaaa
    71461 gaaaagtggg aacagctaac tgaaaaacgt gatcgtttag aagaagagga agaatggctt
    71521 cttcattggc aacagctgga tattgctcca agtatgtatg caagtaagac gaccattttt
    71581 gagatgggga ctgtgagtgc agcaaatttt gaaagtttca aggaagaact aagtaagctt
    71641 gatgacgttt atatggaaga aatagattat acgccaaaac aagtttatct ttcgtatgtt
    71701 gctttaaaaa aatcagttgc tgctatagaa gaaattgctg ggaaatacgg gttcaataaa
    71761 gaaacgtatc cttatgaaca aaatcctaaa gaaaaattgc aagaaaccaa acagcaatta
    71821 tccattgttc acgagcagca aaaaaagata acgacagcgt taggtcagtg cagcggctat
    71881 atccaagaat ttgaatgggt agaagaagtc acacttgccg ttgcagaacg ggaaaaagta
    71941 aaagaacggt ttatccatgc cacttatctg atcgttttgc aaggttgggt agatgcagaa
    72001 gaaaaacaga atttgatgca tgtgttaaac gaaactgtat cagaagaaga tatatacgtt
    72061 agtttcgaaa caccaaactc agaagagatt cagcaggaag tccctactaa attgaaaaac
    72121 catccgctta tcgaaccttt tgaattgctg actgaaatgt acagtctgcc aaaatatgaa
    72181 gaagtagatc caacgccttg gatgacacca ttttatcttg tcttcttcgg gatgatggtc
    72241 gcagatgttg gttacggatt gctgatgctc attgggacaa tactagctca aaaactattt
    72301 gttttacccc gcgggatgaa acgtttcgta aaattctttg agattctctc ggtaccatcg
    72361 atcatctggg gattgatcta cagttcattt ttcggacagg cattaccaaa agaactattt
    72421 ggtatccgct tgcctttccc aatcctatct acgacggatg acgtcaatac gattttgatt
    72481 ttatccgtga ttttcggtct gatacagatc ttggttggat tattcgtggc agcaaaggaa
    72541 aatatcagga ggaaagatta cttgagtgct gtcagtgatg gttttgcctg gcaagggatc
    72601 ctgattggga tcgttattgc attgattggt gtcatgttga taaaaaatac agcatttgtt
    72661 tatcttggcg cggggctatc gatcattgct gctttatgta tcttaatcgt gccgattatc
    72721 caatcgccgt ctaaagtcaa gggtgctgcc aaaggagcgt ataatcttta cggattgact
    72781 ggttatatcg gtgatttagt cagttataca cgtttgatgg cactaggtat ttcaggcgga
    72841 agtattggcg cggcattcaa tatgctagtt gctttcatgc cgccagccgc tcgattcagt
    72901 gtagggatcc ttttgatcat cgctttacac gcactgaata tgtttttgac actgttaagt
    72961 gcctatgtcc atggtgcacg attgcagtat gtcgaatttt ttggaaaatt ttatacagga
    73021 ggcggacgtg cctttgaccc gctgaaaacg gcggaaaaat acgtcaacat caatcataag
    73081 aaaaaaaaca ataaataatt ggaggatttt tatacaatga tggattactt aattagtcaa
    73141 aatggtggaa tggtatttgc agtattagcg atggcaacag cgacgatttt ttcagggatt
    73201 ggttcagcta aaggtgttgg aatgacaggt gaggcagcag cagcgttaac aacaagtcaa
    73261 cccgaaaaat tcggacaggc tttgattctg caattgcttc caggtacgca agggttgtat
    73321 ggattcgtta tcgccttttt gatttttatc aacttaggaa atgatatgtc agttgtacaa
    73381 ggattgaact ttctaggcgc ttctctgccg attgctttta caggtttgtt ttcaggtatc
    73441 gcccaaggga aagttgcagc agcaggtatc caaattttag cgaaaaaacc tgaacatgct
    73501 acaaaaggaa tcatttttgc tgcgatggtt gaaacatatg cgattttagg tttcgttatt
    73561 tccttcctat tagtattgaa tgcctaagca taaaggagga aaagcagatg aacgccattg
    73621 aaaaaatcat ctctcagatg aatgaagcag cagagcaaga aagagcggcg ttagagcaag
    73681 aagagcgaat gaagatcgat caaaactttg aacaaaaacg tacgcaaatc gaaacagaac
    73741 atcaaaaaca aaaagaaaaa caaatcgaat tacttgaaaa aaaataccgt cagcttagga
    73801 atcgccaaca agtagaagta cgacaagaaa atttgaatgc gaagcaggaa tttttacgac
    73861 gattgtttgc agatgcaata gctgaaatgg agaattggga tgaatctgaa caaatccagt
    73921 ttatcaaaaa ttcattgtat tcattacctt tgacaggcaa agtaacattc attgctggag
    73981 aaaaatcagc agcttatctt tctcagacat tgctggatga atggaacaat gaacttccct
    74041 ttatgatggt tttaagtgat gaaactgttg ctgatcaagc gggttttctg ataaacgatc
    74101 aaggagttca gtataatttt cttttcagca gccttgtaca agatatccaa ggaacgatga
    74161 gttttgagat tgccaatcaa ttattcgaat aaggagggat cagtgtatgg aataccacga
    74221 actaaatccc ttgattcgcg gaagagagct tgaacttttg tccaatgaga catttgaacg
    74281 gatgattcaa acaaattctg tcgaagcact tggtgaaata ttgaaatcca cgatttacag
    74341 tccatatatt tatgacggat atgaatatga cttcgaacag aatcttttaa aggagcagag
    74401 ccgtctattt cgctggttaa aggaatcagc accggagcct gaaatcgttt ggatctatac
    74461 gatgcgctat actttccata atctgaaggt tttgacaaaa gccgagatga caaatcaaaa
    74521 tctggaccat ttgtatatcg acgatggatt ttattcatta gaaaccttga aggatgccat
    74581 tcatacgcaa gtttcaaatg aactccctga aagcattatg gacagtatac gagaagtacg
    74641 tgattatttt gaagagtcta ccattcttca gggaattgac gtgatttatg atcgacagtt
    74701 tttgacagag cagcgacggc ttgccgataa gctaggatat caagaattgc tgacagaagt
    74761 cattgctttt attgacttga ccaatatcac aacgatggct cgaggaatat tgcagaaaag
    74821 aacatatggg ttcatgacga cggtactttc cagctcggga agtatcgaaa aagaagtatt
    74881 tttgaacttt gtagataaag atatggaaga ttacacgaat tttctattag agacagatta
    74941 tgctgatttt ctgcgccctg tcatccgtga gggaaatctt gatctcgtaa agcttgaaca
    75001 gttgaaagat gattatctaa gttcattgta tcaagaagca caaacccagg ctttcggacc
    75061 actgccacta ctagcctttt tgaacgcaaa agaggtagaa agcaaaaacc ttcgtttact
    75121 ggttatcggc aaaagaagcc atttcgaacc agaaacaatc agaaagcggg tgagacaagt
    75181 ctatgacgca taagatcggt gtagttggcg acaaagattc tgttttgcca ttcaaattgt
    75241 ttggctttga tgttcgttat ggtacaacca agcaaaccgt tcgtcaggca attgaagaaa
    75301 tggcaaagaa tgagtatggc gtgatttatg tcacagagca atgtgcagca ttgagcccag
    75361 aaacgatcga acgttacaag gaacaaatga tacctgctat cgtattgatt cccaatcatc
    75421 aaggatcatt agggataggg ctggaagaaa ttcaaaaaaa cgtagaaaaa gcagtaggtc
    75481 aaaatatctt atagtatgaa aaggagatag aaattttgca aattggaaaa atcataaaag
    75541 tctccggacc tcttgtaatg gctgagaaca tgtctgatgc cagtatccaa gacatgtgtc
    75601 tagtgggaga tctaggagtt atcggagaaa ttatcgagat gcgtggcgat gtggcgtcta
    75661 ttcaagtata tgaagagact tctggaattg gtccaggcga accggttcgc tctactggtg
    75721 aagctttatc tgttgaatta ggaccaggga tcatttcaca aatgtttgac ggaatccaac
    75781 ggccattaga tacctttatg gaaatcacac aaagtaattt cttagggcgc ggagttcaat
    75841 tgcccgcatt ggaccatgag aaaaaatggt ggttcgaacc aacagtagaa gccggagaaa
    75901 cggtgagtgc tggagatgtt atcgggatcg tagaagaaac aaaagttata aaacataaaa
    75961 tcatggtgcc aaatgggata aaaggaacga tcaaaacaat cgaaaaaggt tcattcacta
    76021 ttgatgaaac agtatgtgtc attgaaaccg aaaatggtga caaaaatttg acgatgcttc
    76081 aaaaatggcc agtaagacgt agtcggccaa tcaaagaaaa attaaacccg gatgcaccca
    76141 tgatcactgg acagcgagtg attgatacat tcttcccagt gacaaaagga ggagcagcag
    76201 ctgtacctgg tccttttggt gcagggaaaa cagtcgttca gcatcaaatt gcaaaatggg
    76261 ccgatgtgga catggttgtc tatgtgggat gtggcgagcg tggaaatgag atgacggatg
    76321 ttttaaatga attccctgaa ttgattgacc ctaatacagg agaatcgttg atggaacgta
    76381 cggtattgat tgctaataca tcaaacatgc cagtagcagc tcgagaagct tctatctata
    76441 cgggaatcac aattgcggaa tatttccgtg acatgggtta tgacgttgct atcatggcag
    76501 actccacttc acgatgggca gaagcacttc gtgagatgag cggacgtttg gaagaaatgc
    76561 ctggtgatga aggttatcca gcttatcttg gttcacggct tgcggaatac tatgaacgat
    76621 ctggaagagt cattgcatta ggatcagaag gtcgcgaagg aagtataacc gcaatcagtg
    76681 ctgtatcccc gtctggaggg gatatttcgg aaccagtcac acaaaataca ttgcgggtcg
    76741 taaaagtatt ctggggtctt gattccagtt tagcccaaaa aagacatttt ccttcgatcg
    76801 attggataca aagctattct ctttattcaa cagaagtagg gaagtatatg gatcatatcc
    76861 ttcaagctga ctgggcatcc atggtcaccg agggcatgcg tattttgcag gaagaacagc
    76921 agctgaatga aatcgtgcgt ttggtaggga ttgattccct ttcagataat gaccgtctga
    76981 cattagaagt ggcaaaatcc attcgtgaag attatttgca gcaaaatgct tttgatgatg
    77041 tcgatacatt cacttcaaga gagaaacaat tcaaaatgtt gaagatgatc ttgacctttg
    77101 gtgaagaagg acgccgtgcg ttgtcgttag gtgcttattt aagtgagatc atggacggta
    77161 ccgtatcgat tcgtgaaagg atcggacgaa gcaaatatat cccggaaaca gaattagaaa
    77221 aactagatca aattattggt gaaatcaagc aaacgatgca aacgatcgtt tcagaaggag
    77281 gcatgagcaa tgattaaaga atatcgtacg atcggtgaag tcgtcggtcc attgatggcg
    77341 gttgaaaaag ttgctggtgt caaatatgaa gaattaatcg aagtccgtat gcaaaatggc
    77401 gagattcgtc gtggacaagt attggaagtc caagaagata aagcaatggt ccaaatattc
    77461 gaaggaacaa gtggtatcaa tttacgtgac tcttctgtac gatttttagg ccatccttta
    77521 gaactaggtg tatcggaaga catgatcggt cgagtattcg atggtttggg acgaccgaaa
    77581 gataacggac cagagatcct gcctgaaaag catttggata ttaacggaga agtaatcaat
    77641 ccagtagctc gggattatcc agatgagttt atccaaacag gtatctctgc aatcgatcat
    77701 ttgaatacat tagttcgtgg gcaaaaatta ccagtatttt ctggctctgg tcttcctcat
    77761 aaagaattag ctgctcagat cgcgcgacaa gcaacggtac tcgattcatc agatgatttc
    77821 gccgtagtct ttgctgctat tggaatcact tttgaagaag ctgaattttt catggaagat
    77881 tttcgtcaaa cgggcgcaat cgaccgttct gtcatgttta tgaatttagc aaacgaccct
    77941 gcaatcgaac gtatcgctac tcctcgtatg gctttgactg ctgcagaata tcttgcttat
    78001 gaaaagggaa tgcatgtttt ggttatcatg acagacatga ccaactatgc agaggcattg
    78061 cgagagattt ctgcagcacg gcgagaagtt ccaggaagaa gaggatatcc tgggtatctt
    78121 tacacgaact tagctacttt attcgaacga gcaggaagaa tccgcggact aaaaggatcg
    78181 gttactcaaa ttccgattct aacaatgcca gaagacgata aaactcatcc aatccctgac
    78241 ttgactggtt atattacaga aggacagatc atcttgacta gagagcttta caagagtggg
    78301 attcagccac caattgatgt actcccgtct ctttcgcggt taaaagataa gggaactgga
    78361 cccggaaaga caagagaaga ccatgcagct acgatgaatc agctttttgc agcctatgca
    78421 caaggaaaac aggcaaaaga attagccgta gttttaggtg aatctgcttt atctgatgta
    78481 gacaagatct atgcgaagtt tgctgagcgg tttgaaaaag aatatgtcaa tcaaggattc
    78541 tacacgaacc gttcgattac tgaaacactt gatctagggt gggaactgct atcgatgttg
    78601 ccaagaaccg aattaaaacg aatcaaagac gacatgctgg acaaatatct gccagaaggg
    78661 aagtgagttc tgatggcacg attgaatgtg aatccgaccc gcatggaatt gactcgattg
    78721 aaaaaacagt tgacaactgc cacaagaggg cataaattat taaaagataa gcaagatgaa
    78781 ctgatgcgtc aattcatcct gttgattcga aagaacaacc agctgcgtca agaaatggaa
    78841 gagtctatga cagaagcaat gtctgatttt gtattggcaa atgcttcgat cacggaacct
    78901 ttcatcgaag aattatttgt tttgccggcg gaaaacgttg atttgtctat cgtagacaaa
    78961 aatatcatga gtgtaaaagt acctgtgatg aattttgaat atgatgaaca gctgacagac
    79021 acacctttgg aatacgggta tttgaattcc agtgccgaac tggatcggtc aatcgatcgg
    79081 tttactaccc tgcttccaaa acttttggaa ctgacagaaa tcgaaaaaac ttgtcaactg
    79141 atggcgagtg aaatcgaaaa gacacgtcgg cgagtcaatg cattagaata tatgacgatc
    79201 cctcaattag aagaaacgat ctattatatt cgtatgaagc tggaagaaaa cgagcgcgca
    79261 gaagtaacaa ggttgatcaa agtaaaaaat atgggtacca ctgactaagt ggtatctttt
    79321 tttaaaagag gaaaacgatg attaaacaaa gcaaacaaat aaagaaacgt ttgccggctg
    79381 ttcagcttct cgcattagga ttttttctcc tgattttagt tggcggcggc ctacttaccc
    79441 taccattttt tagtaatagt gggcatggga caaattttat cgatgcgctt ttcactgcaa
    79501 cttctgctgt ctgtgtaacg ggattgacaa cattgaatac agcagagcat tggaacagtg
    79561 ctggtcaatt tttgatcatg cttttgattg agatcggcgg tcttggtttt atgatggttc
    79621 cgattctatg ctttgcattg ataaagaaga aagtcagtct cagcacacgt attatattaa
    79681 aagaagcgct gaatctagaa gaagtatcag gtgtgatgaa gctcatgctt tacatcctaa
    79741 aattggcctt tgttatccaa ttgattggta cggttgcttt atcttttgta tttgtgcctg
    79801 aatttggctg gttgaaaggt atctggtaca gtttgttcca tgcaatctct agtttttgta
    79861 atgcagggtt tgatttgtta ggagacagtt tagccaatca ccagcaaaat gtttatttga
    79921 tcatggtggt atctgctttg atcatttctg gtgggttagg cttcatcgta tggcgtgatt
    79981 tactggaata tcatcagaaa aagaagatga cgattcattc aaaaatcgca ttaaccgtta
    80041 caggtaccct tttattaggc ggattcgttg tgttcttttt cacagagcgc aatggggcaa
    80101 cgctagtgga agggaatatg tttcaacgat tggcaaacac cttttttatg agtgtgacac
    80161 ctagaacggc tggatattat tcagttgatt acctccatat gagccatgca ggtctgattt
    80221 taacgatgtt tttgatgtac atcggcggaa catctgggtc gacggccggc ggattgaaaa
    80281 caactacgtt aggtgtgttg ctgatccaga tgcgttcgat gttgaaagga cgtacgagag
    80341 cggaagcatt tggccgtacc atccgacaag gcgcagtgtt gcgggcactt actttatttt
    80401 ttgttacgtt gacgttgtgt gtagtcgcca tcatgatttt atcggtgact gaaacgatac
    80461 ctaaaacttc tggcatcgaa tatattgctt ttgaggtctt ctctgcgttt ggtacagtag
    80521 gtcttacgat gggattgacg ccagacttga ctgcaatagg gaaattgatc attatagcgc
    80581 ttatgtacat tggacgagtt ggtgtattga ctgtggtctt ctctctgatg acaaaagcac
    80641 aaagaacaca atcaaaatac aaatatccag aagaaagtgt catgattgga taatttcatc
    80701 ttctgacaga aacctagtga tttagtaaaa taagaaaata aaataatttt tcttgcttct
    80761 tggatacttt aagtgcaaaa tgttcgttta ttttttgagg cactacccgt tgttgaacct
    80821 cgggtagtgc ctctttttta ttgaaaggaa tcaataagat ttgattcctt tatttatcaa
    80881 taggttataa ttcatatttt tttatttttt cttttacgat acttagtcca gaagctaaaa
    80941 tttcaaggtt attagaggat agggaaattc gaacgaatgc atctggttgc gcacgtgtag
    81001 taaagcgtct ggaatgataa agtcggatac cgttagcaag aaagtcattc tcaattatct
    81061 tagggtcaat ctcaggatca actggaagaa ttcgatagta agggacacga ttcgttggtt
    81121 tttctacttt gaaaagagaa tcaaaaagct gattggctct ttttgtaaga cttaatttag
    81181 tttctaagat cctatttgct tcatttgaat ggaggatttg agtgatgact tccacatcta
    81241 atccagaagt tttcacattt atattaaaaa ttgcttgttc tatcttgctt tggacatgta
    81301 ctggaactac aagataagca actcgcaatc cagaacaaat aaattttgtc attccagcta
    81361 agtagattgt ttggttaggt aataaatttt ggaaaggagg aatgatcgta tgttgatagt
    81421 aagttgttaa aaatgaatgg atatcatctt caataaccca tagaccttct ttttcaatca
    81481 cttcggctaa ttgctctcgt cttttgtgag agatttgaaa ccctatagga ttattacaag
    81541 aaggcataag aaagacacca tgaatcttct tttttctaca ttcctgaatc aatatatcag
    81601 gtcgcattcc ttgctcgtca aaatcaattg gaacgatctc taaatgatat aactgagcca
    81661 attcaatgaa attagcgtat gtatatcggt ctgttgctat tctatcacct ggagagaaaa
    81721 gtgcagaaag tgtgatagcc aatccatttt gaacaccgga aacaatagat agagattcta
    81781 aggacggaat gactccttga gtttttaacc aatttgctgc agtagtcaat tgaaaatttg
    81841 tgcctttggg atcttggtaa ttaagcaaac caacaagatt tgggttatta ctagttgatt
    81901 gaataaacgg gacaacgaat ttattacatt cttcaaaaga actaaccaga ccaaaatcaa
    81961 tgatatgttc ggttacttca ttggtagaga tggtgatgga ctcaaagaca ttgggagaaa
    82021 taaatgtgcc acttccaata ttcgtataca gcaaaccttt ctcaattcca tatttataag
    82081 ccttgccaac ggtagtaaaa tttaaatcta aataatcagc tagctctctt tgggagggta
    82141 actgagtgtt tttctgtaat ttattcttta aaatatcttg ttctaattgt tgaatcaacg
    82201 atcgataata aggacgcttc aatttttgtt tgtctggtcg ccaagttaac gggtaattgt
    82261 cataagaatt aataggcatt ttctccactc cttaaaattg tataccatac aattttacca
    82321 ttgattgtat tgattttaga agttaatctt ttgtgaggag ggaattgtct atgaaaatta
    82381 ttaattttga ggaagtagta gcttctttta gttttgaaga agcgattcaa gtaatgaaaa
    82441 aatgtttttt tgattatgaa agtggtaaaa tcagccaaaa tcctcgattg gtggaaattt
    82501 tacctgacgg aaaaggcaaa aatatgtttg cgatgatgcc tgcttatttg ggggagaaca
    82561 gatattttgg cacaaaagtc attaccgctt ttccggataa tcatcagtat catttacctt
    82621 ctcatttagg agagattttc ttgtttgatg ctcaaaacgg actacccaaa gcattgataa
    82681 acgcaaatgc agtcacctgg attcgaacag ctgctgtatc tgcgctggca acagattact
    82741 tagcaaatcc gcatgcagaa acacttgctt taattggagc tggtcaacaa gcattgtcgc
    82801 atttgactgc gatttctacc attcgtccca tcactacagt gtttgtttac gatattttag
    82861 aagaaagacg aaatactttt atcgctaaag ctaaaaaaca gtatcctaaa ataacgttta
    82921 taaatgcaat atcagtagaa gatgcagtac gtccagcgga aatcatttgt acgttgacct
    82981 ctagtaaaga ggcatttctt caaaaagagt gggtaaggga agacgcacat atcaatgctg
    83041 tgggcacatt tactcctgat acaagagaga taagtacatc gttgatggaa acttctcaaa
    83101 tctatgtaga tgattactca gctgccttaa cagaaagcgg ggacctgctt atagccatgg
    83161 cagaaggaga tttagaggaa tcttgtattg ttggtacatt aggcgaatta gtttctgaga
    83221 aaaaaacatt ttataaagga gaatcgaggc cgacgatttt cgacgcagtt ggtctagcta
    83281 ttgaagatct ttgttgtgca gaatatattt ataacaaatt agagaaaggg gctttaaaat
    83341 gaacttagat tattacgtag ttgatgcatt tgcagatgag gtgttcaaag gaaatccagc
    83401 agcggtttat gtgctagaag aatggctgcc agaaggtacg atgcaaaaaa ttgccattga
    83461 aaacaattta tctgaaacag catttacagt gaagaaaaac caagaatttg agcttagatg
    83521 gtttacgcca gatcgagaaa tcgatctttg tggtcacgcg acattagcaa cagcatttgt
    83581 tttatttaac tattacaaaa tacctgatga aacgattaaa ttttctactc aaagcggtaa
    83641 tctatttgtg acaagaatta aagattatta ttacatggat tttcctagta ttatgccgaa
    83701 aaaagtgccg atattgtctg aatatgaaga agcgattggg gctaagatta aagaagccta
    83761 cttagcacgt gatttatttt tcgtattaga agatgaaaaa acggtggcta aattgcagcc
    83821 agattttaca gctatcaaaa attttgaatt aggaatagga gtcatcgtga cagcagaaag
    83881 tgtgcaaaaa gactttgttt ctagaacctt ctttccaaaa ttaacaatca atgaagatcc
    83941 agtatgtgga tcagcacatt ctaatcttat tccttattgg gcagaaagaa tgaataaaac
    84001 aaaattgtca gcttatcaaa tgtcatcaag gggcggggat ctagaatgtg aattaaaaga
    84061 agatcgtgtg ataataggag gaaaagcagt tttgttttct aaaggtacct cgtttatttg
    84121 atttctttca aatgaattaa aaataaattg gtggagagtg gcaaccttat agctacaatg
    84181 gttgttaaaa aaagacgcaa actttttcaa tttaatgaaa agtttgcgtc tcattttaat
    84241 tattggtgtt tgttttttat tcaatcaaga gtaaaatgcc ccatactaac tatcctcgga
    84301 tgacttcgat tttataacca tcagggtcaa tgacaaagta gtaagaaggc gcagtgccag
    84361 gtaatccttt taagtcagta atctcaagac cggcagcttt atgttgctcg tgtaattttt
    84421 ctagatcatc agctgctata gcgatatgac catagccgtc tcctagatca tacgcaccat
    84481 gatcatagtt gtaagtcaac tctaattcat agtcatcccc aggaagtgtc aaataaacaa
    84541 gtgtaaattt gttttctgga aaatcacggc ggcggctttc ttcaaaacca aatgcctttt
    84601 gataaaattc gattgatgct tcaagatctt tcactcgaac acatgtgtga gccattttca
    84661 tagattcatc tctccttttc cttttactca atcataacaa aaagaagtaa ggaaatagtt
    84721 gatttgtgct tgttcatgag aaatttctca tgtaaaatgg atagaaaata aaactgttaa
    84781 ggtggaaact attcatggat aaaccaattt ttggtgaaaa aaagcaattt gctgattatc
    84841 aaacccgtta tgcagcatat attgtcatag aaagagatca gcagattgca gtaatcgagg
    84901 ctccaaatgg tgcttttttt cttcctggcg gggaaattga aggagaagag acgaaagaag
    84961 aagcgattgt ccgtgagctg atagaagaaa tgggaattgt ggcagaaatt tcttcttatc
    85021 tgggagaagc tgatgagtat ttttactcga attatcgtgc aacttattat tataatccag
    85081 gatatttctt tgttgctgat tcttggaagc gtataggaga accaactgaa aagaccaata
    85141 aaatttggtg ggtgagccct caagaagcgc ttgtgaaatt gaaacgtggt agccaccgat
    85201 gggcagtcga gagatggatc gaaaaaaata aaaactgaaa gaaagcgagt agatcagctt
    85261 tctctcagtt tttttattta ttacagtaca tattttttga ttgcttcagc tacaccgtgc
    85321 tcgtcgtttg atgaagtgat gacatttgct gcttctttga caagagaaac ggcatttccc
    85381 attgctactc ctagaccagc atattcaatc atggataagt cgttctcgtt atctccgata
    85441 gccatgattt catcttgatc aataccaagg tgctgtgcga gattcgcaac tgccgcacct
    85501 ttacttgctt ctttatttag tacttcgaag taatagggcg cacttttgac cgttgtgtat
    85561 ttatcacgga aagtttgcgg taaacgcgca attgctgcat ctaaaatttc tggttcgtcg
    85621 atcatcatca ttttgacgat gttcatgtct ggtgtcattt cttcaggtgt tcgatatttt
    85681 agcggcatct tgactaaact tgcttcgtgg atcgtataag cgctgatatc tcgattaggc
    85741 gtgtagatcg ctttgtcatc gatcgaatgg agatgactgc cgacacggcg tgccatcact
    85801 tcgatctcta ggaaatcttc atgtgtcagt ccgtgacggg cgatgatttt acctgatttc
    85861 gtttgttgta cgagtgcccc gttataagta ataacgtaat cattatcttg aaaaaggttc
    85921 aactcgttta actgttcctg gacacctggt aagggacggc cagtgcataa aacgatcgaa
    85981 acaccttttg caacagcagc ggcaatcgct tcttttactt cttttgttac ttctcttttc
    86041 tcatttaata aagtaccatc gatgtcgata gcgactagtt tgatagacat aatttcctcc
    86101 aatatatttt aatttatttc aatcaatgcg ccattacgga tatggctggc aaattcttga
    86161 taagtttcgt caaataaatc ataatgatca cgcaaggacg gatcaaccat ttcttttgga
    86221 aagaaaaatc gctcatctcc ttgttcttgt cccgctaatg cagcaacaag ctgactaacc
    86281 tgtgataatt ctatcaaagt tccgtcattt cgcaaaatct cgatttgtgt gcgatgtctg
    86341 ccttgttctg ggcgataaaa atcataaggt agatcgtagc tagaattcac agcagtgtaa
    86401 taaacaggat tatatccgac cttttctact aacaaagtga gttcttggac taattttgaa
    86461 tcccggttgc cagaaaaagt agcagatttc agtggtttac gattcaaaaa acgtttagct
    86521 aaatcattta aaataggatc agcagattca gaccattgag taaagtaagt gcccaagacc
    86581 ccatcatcaa gtttgaggta ttcttctaaa gtaaagcttc cgtcaagaaa tggcagaagt
    86641 aattgagaat ggagttcaaa actgctggca tcttcttgat acaactcgtg tgcgcgatga
    86701 agcagatgct ccaaaattac ttccatacca cgggaaacag gatggaagta cacttgcaca
    86761 tacatttgat atcggctaac gatataatct tccactgcat gcatgccact catggaaaaa
    86821 gcgatcccgc cttcataagg acgaatcaca cgtaatattc gggtaagatc aaatgttcca
    86881 tattctgttc cagtgaaata agcatcccga agcaaatagt ccattcgatc tgcatcgatc
    86941 tgactagaaa tcatttggac aacttgtggg ttggggtaag ttttttggat cacactagct
    87001 accttttcag gaaaaccttc ttctactcgg ttaagaatct gatacacttc tgtttctgga
    87061 gaagtgatga tctctacagt gatggcttca tgattcgtat ggaagatatg ttcaaatgta
    87121 tgagagtaag gaccatgacc gacatcatgc aacagtgccg cacataaagt caccagccgt
    87181 tcctgatcat cccagcctcc gttgcctatt ttttcttttg aaaaatttcg agaaaagata
    87241 tcgcagattc gtcttgaaat ctcataaacg cctaatgaat gagtaaaacg gctatgttct
    87301 gctccgtgaa aagtgaaaga agaagtgcct aattgtttaa tgcgtcgtag acgttggact
    87361 tctttcgaat tgatcaaatc taagattact tgatgctgga catggatata gttatggact
    87421 ggatcacgaa aaactttttc cataggcagc atttgatatt tataaggggt tgtcataatg
    87481 tagctccttt atgttattac gttgttccat tctctggatt tggttgttcc attgctccag
    87541 ctggatttct ttttttagcc agtcggtaga atcctgtaaa tcacttgcag aatacagctt
    87601 ttcaaaagct tttgcaaatg cttctttgac ttcttttaca aaaaggggtt ggtcaagcag
    87661 ttcttcaagt gttgccattg tagcaggatc cactgcagga tagccatttg taccaaagtc
    87721 ttcttttaaa gcagattgat aaaatcgctt catgacttgc ccgcgttttt cctgattacc
    87781 gttgacactt aagtacatca taacagaaat cccatttttg atccgacgct gagcgatacc
    87841 ggcaaatttt ttgccatgga tgcttaaatc ataagttcca ggacaataag aatgggtgat
    87901 ttcgaatgct tgtatcggtg cctttggaaa agcgtattta gtcaatagga gcatttgctc
    87961 gtaagcgtca tctatggtta ttttttttgt gtcactttgg gggaaaatca aagaaatatt
    88021 caaaattcct tcatctgata cgatccctaa tccacctgaa tttctgatca ctggagcgta
    88081 acctgcatct ttcagtgttt ggatcccgtc acttagaaaa ggagttcgaa catccttcat
    88141 acctaagatg actgtgcagt catattgcca gaaatgtaaa aagatttgct ggtgttcttt
    88201 agaatattcc gttaatatat ctgttaatgc aaaaggggaa aagtcgtttt tttgataaat
    88261 gtgctgatct agtcgaatcg cagggttcat tcaaccggct cctttgtata aattcatatt
    88321 ttctacaata ttatactcta aaatcaaaga gttgttttgg aaaaaaggtt ttctgtaaaa
    88381 atggacaagt tggttgacaa aacaaaagaa actaggaaca atgtagctat gagaagtaaa
    88441 ggagaatgaa taatggaatt atcacaagga acaccgattt caatcaaatt gcgtacaaaa
    88501 gtaaaacagc aaggggaagt gcaagatttt tattttgatt tgaaagggca aatggtgaca
    88561 attggcgata cgctgtacat acgttataaa gagattcagg aggagacggg cgatgagatt
    88621 cctgtaacga tcaaattagt tccagatggt catgtacagc tgatccgtgc aggagaaatg
    88681 cggatgcgtt tgaaatttgg ctataaagaa cggttagaaa catcctatcg aacaccatac
    88741 ggtatgatcc agattgctac ttttacgaaa gaactgcatg ttagtttgaa agaccgtccc
    88801 acaggaggga aggttcgaat cgattatgat ctgttcatgg gaccggaaaa aatcggcgaa
    88861 tattatttga ccttggattt tacagcgtaa atataaaaga aaagtttgat tttttgtgtc
    88921 tgattttgta tgataaggag tagactgtga aaggacgtgt cctgattgga aattagtgta
    88981 tttgaaggtg caaacaaaag cgaattatca atgatcgaag tagcacacgc gatcttagaa
    89041 caacgtggcg atgtcatgga tttttctgat ttagctaacc agatccaaaa ctatcttggg
    89101 aaatcagaca gtgaaattcg tgattcactc gcacaatttt atactgactt gaatattgac
    89161 ggcagcttta tctcattagg ggataatcgt tggggcttgc gttcatggta tgctatcgat
    89221 tcgatcgatg aagaagtaaa ccatggaatg gacgaagagg atgaagatac tccacgtcgc
    89281 cgtaaacgca agaaagtcaa cgcctttatc aatgatgatg aagacgcgat cgattacaat
    89341 gacgatgacc cagaagatac agatctgaca gaagaagatg acgatgatct gtttgatgac
    89401 gatgatgatg aagatgaaga aatcgctgct tataattctg acttgcaaga aatcggagca
    89461 gatgacccga cagatgatga agaagacttg ccaggaaata tcgaagaaga tttaagtatc
    89521 atagacgaag acgatgatga tgaagattat gaagaggaag aattttctga ctctgaaaaa
    89581 gaataaacat tattttctta cgagaggttg tgacagagac gatcagccta tcagaataag
    89641 gaggtgtgac acgatttttg tcacaccttc ttttttgtat ataaaaatcc caagtaaata
    89701 cataaaaaat aaaaaaattg aaacttttag cgcaccttgt acgtcatatt aagtgaggca
    89761 gaaaggagtg gagaatgatt tttactggat ataagaaaaa acggcagatc gaaaaatacc
    89821 gtcacctgct gaatggactc atcgaaactg attatcaaaa aatgttccgt atcacgatga
    89881 attacgtaca tgataaagaa gaggccttag atgtgatgca agatagtttt cataaagccc
    89941 tgaactattt tgaaaaagaa aaagagatcg agcattttag tgcatggttt tatcggatat
    90001 tgatccgcac ggcattagat agttggcgca gacaaaaaag gacgcctgtg gacttatttg
    90061 aaattcaaga tatcccccaa cagttacctt tagaaacttc cgttgcagag ctccatatga
    90121 ttttagataa aatagacagt ccggaaaaag agattctgat cctctacttt tttgaaggat
    90181 ttcgtttgaa agaaattgcg actatcttgg atatgaatga aaacacagtt aaaacgaaaa
    90241 tgtaccgctc attgaatgct ttacgtcaaa tcctagaatg aaggagagaa gagtgccatg
    90301 tattcccaaa aagaaaattt aaaaaaacta aagaaaactt ataaagaaca agcaattccc
    90361 aaagggctta aagaggagat ccgccagcgt tttattatcg aagagcaatc atttataaaa
    90421 gcaaagcgga gaaagagacg tctccaaggg ttcggagtat ctttggctat cgtaatgatt
    90481 acaacaagta gccttctttt taatagtcaa gttcgaagct ttgcagaaga tttacccatc
    90541 ttaggatcag tcattgaatt gatcttaggc gaacgcttta ctgatcgatc tgaaaaaatc
    90601 gatattcagg taccgaagat caatacacaa aatgagaaag aaaataaaac aattcatgga
    90661 ttaaatcaaa aatactttcg cgaaggacaa gcagattttg aaaaagctga aaaagaatat
    90721 ggaaattttg aaacggatca ttaccaagtt ttgggagatt atcagaaaat cgtagacgat
    90781 aaccggtttc tcgtgattga aaggcagatc acccaaacag cagcagatag ccatgttgaa
    90841 aaaagatacg acacaatcga caagaaaaac agtgtccagc tctcacttcc acttttattc
    90901 aaagatgaca cctatctatc tgttttgaca aaagaagtca aacggcagat ggccgaacaa
    90961 gtcaaggaag atccatctaa gtactattgg actgagcaag atattcaaga agggacgata
    91021 gaaaaaccaa cacttgttac gcctacacga agtttttatt tgaacaaaga gcatcaatta
    91081 gttttgactt tttctcaata cgaaattgct cctggttata tgggtacacc agaatttgtc
    91141 attcctaagt ccgtgacaaa aacgattttg gcatcggaag attatttgga tcattagacg
    91201 agaagtagtt gcgactagca gtttcaattt tcaagtaagt acaagtaaat aataagaaga
    91261 gaaaaagaga aagaagagat atagtgaaaa gaaattattt agttatcagt attattgctt
    91321 tatccgtgct tttgtttttc gaaattactt cggtggcctc cttgatcacc gaagtaaaag
    91381 gacaaacaca ctcttcggag cattcgtcac aatctttcaa acaatcagaa caatcaacca
    91441 ttaaaagcca atcaactgaa acagctaacg tcaaagaagc cattcaagaa tcagcggaaa
    91501 aggtacaaag tcagtcatca caatcaacac aagacagtac aaaaacgagc cgagatccgg
    91561 ctgtcaaaag cgtcgcaatc agctttgatg atggaccagg agcgaccaca acaccgcagc
    91621 ttctgcgaat cttaaaagaa aaaaacgtgc atgccacttt tttcgtctta ggagaaaata
    91681 cggcgcagca tcctgaaatc gtgaagcaga cagctgaagc agggcacgag attggcaatc
    91741 acacatacga tcatcagaat ctggccactc tttctgccca gtcgatgacg gaggaagtga
    91801 cgaaagcaga cactgagatc aaaaaagtca ctggcaaaac ccccactttt gttcgtccgc
    91861 cctatggttc tgtcacgaat gtaggagcaa cgatcatcca gcgaccgatc atcgaatggt
    91921 ctgttgattc agaagattgg aagacaagaa atcctgattt gattttgcag aagatccaag
    91981 caacagtata cgatggggca attattttat tccatgatat ctatcctgaa acgattcgtg
    92041 ccgttcctca agtgatcgat tatctgaaag agcaagggta tcgcatcacg acagttgggg
    92101 atttattagg gcatccaacg gctgtcgaga actattatgg cagaaacgat catcggccag
    92161 ttcagtaagt gagacaagta tctttaataa ataacacatt ttaataagta gttgaacaca
    92221 taactacctt acttgcaaag gcttaacaat atctatacag gtacaacaaa aaactgtcca
    92281 ccaattttct ttggcggaca gttttcactt aaaaataaag aagcaactat tcgtaaatta
    92341 tgctaaaata gcagtagaac gcgtcctgag ggaatcgaac ccccgtctca agaaccggaa
    92401 tcttacgtga tatccactac actaaggacg caagcactgg gataattgta actaaacaga
    92461 taaaaaatta caaggggatt ggacaaaaaa atgaaatttg agcaaaattt ttcacaaaaa
    92521 cagcagcaga cacagaaact agccatgacg caacagttgc aacagtccat ccaagtttta
    92581 caatataaca gtgaggagct gttggcattc gttgagaatc aagcaatgga aaatccattg
    92641 gtggaagttg ttgagccgga atggcagcca gattacataa aagcttcttc atcttcttat
    92701 gaaggagaag agacaaatta cctaaatcag attcctgata caaaagggtc tttatttgat
    92761 tcattgatcg aacaagtcca tttgaattac cgagatactt ttttgaggaa aatcgttctt
    92821 tatcttgtag aatacatcga tttgaacgga tttttgacga ttagtttaga agaagccgga
    92881 aaagagattg gagctacgcc tatccaaatg ctcgatgcgt tgactctgat tcagcaatta
    92941 gaaccagctg gagtaggtgc acgtagtttg caagaatgtc tcatgcttca aacagaacga
    93001 gatgattatg cgccggaatt agcttatatc gtgttggaag aatgttttga ggaactggtg
    93061 gagcgaaaat ggaaagaaat cgcacaacgt ttttctgttg atctacatgc tgttcagcag
    93121 atattcgact atttacaaac gttgagtcca agccctggcc ggattttcga ccgtagcagc
    93181 gaattgtaca ttattcctga tgtccgggta ttagtggacg acgataaaaa tgtacaagtt
    93241 atctcaaacc gaaaaaatca gccaaatata cgctttcaag agagttactt caaacaaatg
    93301 tcacaacaag cagataaaga aactgaaaat tatttaaaag aacggaaaca ggaattcgaa
    93361 tggttgaaga aaacgatcct acaacgtggg gatacaattt tgcgggttgc tcaagtcatt
    93421 gtttcccggc aaaaagcttt ctttatcgac aaggaacgtc caatcaagcc tcttacgtta
    93481 aaggaagttg caactgagat agatgtgcat gaatccacgg tcagtcgtgc agtcaacggg
    93541 aaatatttgg aaacagactt cggtgtattt gaattaaaaa aatttttcac tacacgaatt
    93601 cctacgaata gtacagaaca gacagaagac ctttcagcag atacagcgaa gaaaaagctg
    93661 caggaattag tcgatcaaga agacaaaaac aagccgttgt ctgaccagaa attggttgaa
    93721 ttgctgaaaa aagatgagat agcgatctca agacgaacag tagcaaaata tcgtgattta
    93781 ttaggaatcc cgagttcatc aaaaagaaaa cgttatgata actaatcagt caaaagacta
    93841 gaaaaagtat ttcacttttt ctagtctttt tagttgaaaa acgagagcaa aactgttaga
    93901 cttacagtcg tgaggttgag atttcccttt attgatgtga aattcgaata gttaatttct
    93961 ttttttatcg tatatgggtc gttttaagtc tacattggac gtaaagtgtc caactaagga
    94021 gatcgctatg ctggatgaaa taaaaatgat tgaatctgtt gcaccagata ttatcgaagt
    94081 gttgcaagaa cgctataaaa ttttacgaaa tatctattgg atgcagccga ttggacgtcg
    94141 aagtttatcg gaaagtatgg ggatcacaga acgagtattg cgaacagaaa cagatctttt
    94201 gaaaaatctg aatttgatcg acacctcaaa aagcggtatg acgctgacaa ctaagggcga
    94261 agaagtttat caaagccttg aaaacttcat ggatcagctt ttaggtacgc atcaaaccga
    94321 acaacagttg gcagaatatt ttggtaacca acgctgtatc gttgtttcag gaaacagcga
    94381 agagcagacc aaagtggctg atgcattcgg cgaagcgctg agcgaagccc tagaccgact
    94441 acttccagaa ggcgagaata tcatcgctgt gatgggagga actactatgg ctgtggtagc
    94501 cgaacaattg tctaatctgg aaaataagaa acggcataac ctgtttgtcc ctgcaagagg
    94561 cgggattggt gaagcgataa ctgtacaggc aaattctgtc agtgcaagaa tggctgctaa
    94621 agcaaacggt aaccaccgtg cactttatgt tccggaacaa ttaagtctgg caacttacaa
    94681 ttctttactc aatgagccat ctatccaaga agtcttaaac ttgattagtg aagcgaattg
    94741 tgttattcat agtattgggc gtgcattaca catggcagca cgtcgtaaga tgactgaaaa
    94801 agaattagtc atgctgaaac aagcaaatgc tgttgcggaa tcttttggct actttttcaa
    94861 tgaaaaaggt gaagtcgttt ataaggtccc tagaatcggc atagaattgc aagatttgga
    94921 aaaagtcccg atcatcatgg caatcgcggg cggaaaatca aaagccaaag caattcgagc
    94981 ttatatgaaa aatgcaccaa aacaaacgtg gctcatcact gatgaagctg ctgcaaatga
    95041 gattttaaaa ggggtaaccc tttaaaataa atattttttt gattttcata aggaggaaat
    95101 cttaaatgac agttaaagta ggtattaatg gttttggacg tattggacgt ctagcattcc
    95161 gtcgtatcca agatgtagat ggaatcgaag tagtagcaat caacgacttg acagatgcta
    95221 aaatgttggc acacttgtta aaatacgaca caactcaagg acgtttcaac ggaacagttg
    95281 aagttcatga aggttcattc aacgtaaacg gaaaagaagt taaagtatta gctaaccgca
    95341 acccagaaga attaccatgg ggcgaactag gcgtagatat cgttctagaa tgtactggtt
    95401 tcttcacttc taaatcagca gctgaaaaac atttaacagc tggtgctaaa cgcgttgtta
    95461 tctctgctcc tggcggaaac gatgttccaa caatcgttta taacacaaac cacgaaacat
    95521 taactggtaa agaaacagtt atctcaggtg cttcatgtac tactaactgt ttagctccta
    95581 tggctaaaac attgaacgac aaatttggtg ttgttgaagg attaatgaca actatccacg
    95641 cttacacagg tgaccaaatg actctagacg gacctcatcc taaaggtgac ttccgccgtg
    95701 cacgcgctgc tgctgcaaac atcgttccta actcaacagg tgctgctaaa gctatcggtt
    95761 tagtaattcc tgaattgaac ggtaaattag acggagctgc tcaacgtgtt cctgtaccaa
    95821 caggttcatt aacagaatta gtaacagttc ttgaaaaaga agtaactgtt gacgaaatca
    95881 atgcagcaat gaaagaagct tcaaacgaat cttacggata caacacagac gaaatcgttt
    95941 cttcagatat cgttggtatg acttacggtt cattatttga tgctacacaa actaaagtaa
    96001 tgacagttgg cgacaaacaa ttagttaaaa ctgttgcttg gtacgacaac gaaatgtcat
    96061 acactgcaca attagtacgt actttagaat acttcgctaa cttataagat agacaaacgt
    96121 acaagtgtaa attatagaca tgtacattta aaagcgggga agcaatcgcg cttcttccgc
    96181 tttttttgat aataagttta ttcaggagga aataaaatgg ctaagaaaac agtgaaagat
    96241 atcgatttaa aagacaaaaa agttcttgtc cgtgttgact tcaacgttcc tttgaaagac
    96301 ggcgtgatca ctgacgacac tcgtatcaaa gcagcattgc caacaatcaa ctacgttcta
    96361 gaacaaggcg gaaaagcaat ccttttctct caccttggac gtgtaaaaac agaagaagat
    96421 aaagaaggaa aatctttagc tccagttgca aaacgtctag gcgaattatt aggtaaagaa
    96481 gtaacattcg tacctgaaac tcgcggagaa caattagaag aagcaatccg caacatgaat
    96541 gacggcgacg ttgtcgtatt cgaaaataca cgatttgaag atattgacgg taaaaaagaa
    96601 agcaaaaatg atacagaact aggtaaatac tgggcttcat taggcgatgt atttgttaac
    96661 gatgctttcg gtacagctca ccgtgcacat gcttctaacg taggtatcgc ttcaactggt
    96721 atcccaacag ttgctggatt cttgatggaa aaagaaatca agttcatcgg tgaagcagta
    96781 gaagaaccaa aacgaccaat gattgcaatc cttggtggcg caaaagtttc tgataaaatc
    96841 ggcgtaatcg aaaacttgat tcctaaagca gataaaatct tgatcggtgg cggaatgact
    96901 tacacattct acgaagcaaa aggaatcaag atcggtaact ctctagtaga agctgataaa
    96961 gtggaactag caaaagaatt aatcgaaaaa gcaggcgaca aacttgtctt gccaatcgac
    97021 aatgtctgtg caccagaatt ttcaaatgat gttgaaacac aagtaatcga aggagacatt
    97081 cctgatggtt tgatggcttt agacatcggc ccagcatcag taaaattatt tgctgataca
    97141 ttacaaggtg caaaaacagt tgtttggaac ggacctatgg gtgtatttga aatgagtaac
    97201 tttgctaaag gtacaatcgg tgtttgtgaa gcaatcgcta acttagaagg cgcaacaaca
    97261 atcatcggtg gcggagactc agccgcagca gcagaacaat taggatttgc tgacaaattc
    97321 acacacatct caacaggtgg cggcgcaagc ttggaattgc ttgaaggtaa agaattacca
    97381 ggactagcag caatcaacga taaataaacg accaagtttg ctcaattctg acgagtaatc
    97441 gatcaaaagg tgaagggagt tttcatgact ccctagccat ttttcaataa attaaggagt
    97501 gtgttcctca atgcgtaaac ctattatcgc aggtaactgg aaaatgaaca aaactgcatc
    97561 agaagcaaaa gaatttgctg aagcagtaaa aaacaaaatc ccttcaaatg acaaagttga
    97621 ttcagtcatc ggatctcctg cattattctt acaagaatta atgacatcag ctgaaggtac
    97681 agaactaaaa atctcagcac aaaactgcta ctgggaaaac tcaggtgcgt tcactggtga
    97741 aacttcacca gcagctcttg ctgatctagg tgttcattat gtgatcatcg gacattcaga
    97801 acgtcgtgaa tatttccatg aaacagacga agacatcaat aaaaaagcga aagctatctt
    97861 tgcaaatggt atgacaccaa tcctatgctg tggcgaatct ttagaaacct atgaagcagg
    97921 caaaactgct gaatggatcg aaggacaaat tacagctggt ttagctgatc tttcagctga
    97981 acaagtgtca aacatggtta ttgcttatga accaatctgg gcaatcggta ctggtaaatc
    98041 agctgacgca caaatcgctg acgaaatttg tggagttgta cgtcaaacag ttgaaaaact
    98101 ttatggaaaa gaagtatcag aagcagttcg tatccaatac ggcggttctg taaaaccaga
    98161 aaatattgct gaatacatgg caaaagaaaa tgttgacggt gctttagtcg gtggcgcaag
    98221 cttgcaagca gattcattct tgtcattgtt agacgctgta aaataattgt tgaaaatttg
    98281 cgaaaaatgc aagaaatgtt tgcactaatg agcaaaatta actaaaatcg tatatgaggg
    98341 aaatccctta ggaaaaaaca aactcaaagg agagacaaaa catgtcaatt attactgatg
    98401 tttacgctcg cgagatctta gactcacgtg gtaacccaac aatcgaagta gaagtataca
    98461 cagaaagcgg agcttttggc cgcggaatgg ttccttcagg tgcttcaact ggtgaatacg
    98521 aagcagttga attacgtgac ggagacaaag ctcgttatgg cggtaaaggt gtaactaaag
    98581 ctgtcgacaa cgtaaacaac atcattgctg aagcaatcat tggctacgat gttcgtgacc
    98641 aaatggctat cgacaaagct atgatcgctt tagacggaac tcctaacaaa ggtaaattag
    98701 gtgcgaacgc tattttaggt gtttctatcg ctgttgcacg tgcagctgct gactacctag
    98761 aagtaccttt ataccactac ctaggcggat tcaacacaaa agtattgcca acaccaatga
    98821 tgaacatcat caacggcgga tcacatgctg ataactcaat cgacttccaa gaattcatga
    98881 tcatgcctgt tggcgctcca acattcaaag aagctctacg tatgggtgct gaagtattcc
    98941 acgcattagc ttcaatcttg aaagctcgcg gattagcaac ttctgttggt gacgaaggtg
    99001 gatttgctcc aaaccttggt tcaaacgaag aaggttttga agtaatcatc gaagcaatcg
    99061 aaaaagctgg ctatgtacct ggtaaagacg ttgttcttgc tatggatgct gcttcttcag
    99121 aattctacga caaagaaaaa ggtgtttacg tactagctga ttcaggcgaa ggcgaaaaaa
    99181 caactgacga aatgatcaaa ttctacgaag aattagtttc taaatatcca atcatctcaa
    99241 tcgaagacgg attagacgaa aacgactggg acggattcaa gaaattaact gacgtattag
    99301 gcgacaaagt tcaattagtt ggtgacgact tgttcgtaac aaacactcaa aaattatctg
    99361 aaggtatcga aaaaggaatt gctaactcaa tccttatcaa agtgaaccaa atcggtacat
    99421 taacagaaac tttcgaagct atcgaaatgg ctaaagaagc tggctacaca gcagttgtat
    99481 ctcaccgttc tggtgaaaca gaagattcaa caatctctga tatcgctgtt gcaacaaacg
    99541 ctggccaaat caaaactggt tctctatcac gtactgaccg tattgctaaa tacaaccaat
    99601 tactacgtat cgaagaccaa cttggtgaag ttgcagaata caaaggtttg aaatctttct
    99661 acaacttaaa aaacaaataa ttcttttcta atgaagatac atgatcgact attgaaagat
    99721 agtcgagtat gatcacttag ttaagtaatc gaactctcta cttgctgaaa tatcagcagg
    99781 tagagagttt tttttgcaac tagcttctgt atatgatgtt tacaaagaat ggtacaagaa
    99841 aagatcatcc ttgaaaaagg aaagctaaca ataactagca tcatataaga gcttttaagg
    99901 atagaacagt agaataggaa tctatgagca agtcctctcg tataaataaa ataggaggga
    99961 agtagcagca tatttttcat aaagtggctc tctttcttca tttttacttt ggttgctcct
   100021 atttgaaaat tcgagcacac tcaaatacaa taaaaagaaa tggcaaggga gaggattaga
   100081 tgaaaaaaga agaaaaaatc gcgattttac aagagatcat ccgaattaaa tcagtgaatg
   100141 gaaacgaagg tgaagtagca gcctatttga ataagctttt ggcaaagcat gacataacag
   100201 gagagattgt ttcttacaga gatggtagag ataatttgat tgctcgttac caaaagggcc
   100261 aatcaggaaa agtgttaggc ctatctgggc atatggatgt cgtggcggct ggtgatgaat
   100321 cgtcttggac ctatgcaccc tttgcagcag aaatccatgg gaaccgtttg tacggacgtg
   100381 gtgctacaga tatgaagagt ggcttggcag caatggtgat tgccatgatc gaactgaaag
   100441 agtcaggaaa accatttaac ggaacagtca aattattagc cactgtcgga gaagaagtgg
   100501 gtgaactagg tggggaacag ctcacgaaag caggctatgt agatgactta gatgccttga
   100561 tcatcggaga gccaactaat tacagtttga tgtatacgca catgggatca atcaactata
   100621 cagtcacctc gcacggaaaa gaagcgcata gctctatgcc agaccaaggt tataatgcaa
   100681 tcaatcacct aaatgaattc attacgaaag caaatgctga aatgaatcac ctcgctgaaa
   100741 caatcgagaa tcctgtccta ggaaaaacaa tccataatgt tacattgatc agtggcggga
   100801 atcaagtcaa cagcatccca agccatgcgc agctccaagg gaacattcga tcgattccag
   100861 aatacccaaa tgataaaatc attgcattgc tgcaatcaat cgtcaatgaa ttgaatcaag
   100921 agacagacta tcatttggaa ttgatgatcg attacaacaa aatacctgtc aaagctgatc
   100981 cagattctcc tttgattcat tgcattcagc aacaattcag ccagccatta cctttagttg
   101041 gagcggcagc aacaacggat gcagccgaat ttacgaaagc taaccattcc ttcgactttg
   101101 tcgtctttgg gcctggtgtc gttactttgc ctcatcaagt agatgagtat gttgaaatcg
   101161 ataattattt ggatatgatt gaaaaatatc aaggaattat tttatcctac ttagcgtaag
   101221 atttttttaa taaatgaaaa aacagagcca gattagcatt attttgctaa tccagctctg
   101281 tttattcagc ctatttttct ttttgaatat atcaagcgtt gtggcaacat agtgatgact
   101341 aatgaaacaa cgacgataga caacaaacga tcaaggtagt ctgtacctgc ctgtaccaag
   101401 atcacacttg ttgtctgact taaacctaac ccatgtaata gctgaacgat catactggat
   101461 cctgaggagg tgatcccgcc aaataactga acggtaatga tcgaagaaac gatcgttcca
   101521 ggtaccgaca aaatcaaagc gagtaataac agtttcaagc tgtttttatc tttgccgaga
   101581 tatcttggca aaatcaatcc agcaagcaag cctgtgagaa tttggattgg cgaataatac
   101641 agagaaaaaa tatctgtagt cactccactt aaaataccgc tggacaatcc tgtcagcatt
   101701 ccaggtacag gcccaagcaa tgcaccagca aaaatcgttc cgatagaatc gagatagatt
   101761 ggcaaacgaa gccataaagc aatcgttcct ccaatataat tgatcccaat acacaaagcc
   101821 atcactgtaa gtacgcgagt tgccattttg tttttattca ttttgttagc ccatctttaa
   101881 cctttccaaa tctttcataa tcgtttcttc ttgtgcattt aaaagaacgg ttaaaaactt
   101941 tcggaaaaaa agacgagtat ctacttttgt cataatttta ctgttagcag gtttctgcca
   102001 aaattcataa cgatcaacca atgtttgtcc acgacttatt ccttgagttt ccacagcagt
   102061 gaagcttttg aaaccttcac agatggcccc ctcgataaaa taagcaacag ctaacggatc
   102121 attgatgaca catcctaaaa ttctttcttg tttccagtgg aagtcaaaat aaaaacgagt
   102181 gatcgctttt agatactctc cctcttcagg attcatttga cagcagtatt cgaggatagt
   102241 cggtgtcaag acgatttctc ttgtcacatc taacccaacc atttctatcg tttgtttgag
   102301 attctcgaat acataagaag ctgcttcagg atcacaccag taattgtatt cagcaactgg
   102361 cgaacagtta ccatggcttt tgtaagttcc acccatcgag acaaaacgat ccatatgttt
   102421 cccaatattt gggttgactt tcaaagcaaa agcgatattg gtcaaaggac ccaaagcaat
   102481 gactgatgta tttgtctttt ctttgaaata atcagccaaa aaatcaacgg catggagagg
   102541 ttctgcctgt tttctcaaga tcatcgggaa atttgtttcc cctaaaccat ccataccatg
   102601 agtgtcttgt gcactgatga aaggttgctt caaaggtttt tccattcctt gataaacagg
   102661 aatgtctaaa cgatcacagc gttccaggca tttcagcaca ttctgcgtac ctatatctgc
   102721 agggacattc ccacaaacta cggtaatagc aactacttcg atatcagggg atttgacagc
   102781 taatgataaa gctaaagtgt cgtcgatccc tggatcgcaa tcaataatta cttttcgcat
   102841 tatttccaat ctcctttctt tagagatact tagtttttta ttctgggaag tttccgaacc
   102901 agtccaagac gagcgtcttg attataatgc acgaaattag tatactggct tttattgcga
   102961 atgtaaatgc tctcttacaa gtaaatctat tgaggagaac tttaagtaaa tgatacaatg
   103021 aaaaagaaat ggaatttacg tgtgccgaaa ataaagaatc ctatggatcg gtacattgga
   103081 taatagttag attatagttt ggcagaaagc ggcgggtgta caatggttat tttttatttc
   103141 attcttattc tgataattat agggatcagt taccattttc tttcttattt ttatgcaaag
   103201 aaattagtaa gagcgggagt acagagagga tatgactggt atgaagacac tggtcatcgt
   103261 ttgatggacc ctgctgcagt cacgtcagta gaaaaaaaac gacaaaaatt agaagaagag
   103321 tgtgaaagct tttgggagca gggaacaccc aaaacaatca aaagttatga cgggttgaaa
   103381 ctagctggtc agatgttcat ccatccaaat aagcagaata aatgggtcat ttgcgtacat
   103441 gattaccgaa gcacagggaa aagagacatg tctcatatag gtaaaagata tgcagagaaa
   103501 ggattcaacg ttcttgtacc tgatttacgt gcgcacggag aaagtgaagg agaaatcatc
   103561 ggaatgggat ggctagatcg gctagattta attgcctgga tccaactcat cttagatgaa
   103621 cagccgaatg cgtccattat tttacacggc ggatcaatgg gagcttctac gatcatgatg
   103681 gcaagtggtg aaaaacttcc atcagcggtc aaaggattta ttttagacag cggatatgtt
   103741 tctgtttatg cagaattccg atatatgtta agtaaaatca ctgtctttcc taaaaaaatg
   103801 gtcatgagat atgcgaatca ttatgcccag aaatacgccg gttactcctt aaagcaagca
   103861 tcagctacga gacagcttgg cagcaaccat ctgcctttat tggtcattca tggtgaaaga
   103921 gatcattttg tccctacaga agcagcgtac acgattcaaa atgctacggc aggggataaa
   103981 gcactgctgc ttgttccaga agcagaacac ttggaagcat cgatgaaaga tccgaaaacc
   104041 tattggacag tgattttttc atttattgaa caaagaataa cgatgaatta attttctctt
   104101 cttttttgta agtaattcga ggataaataa ttgtttatag atcaggagac tgctaaaata
   104161 aggtaggaat aaaaaaatat cagttatttg aggagtgcgg catatggaaa tcaaagaaga
   104221 aaaaaatcgt cttgctttat tcaatgatga acaacaagag atcggagaaa tgacatggtc
   104281 agatgcgggc ccagacatca tgatcattga ccatacattt gtagatccag catatcgtgg
   104341 tcaaaagtta gctgaaaagc tagtgtatac tggagtagaa ttagcaagac gagacgggaa
   104401 aaagatcatt cctttatgcc cttatgcaaa aaaagagttt gaaaagaaac cagaatatca
   104461 agacgtctta cgtcagtcat aagaataaca gctgaaagtt ttgaactttc agctgttatt
   104521 ccatttatat agagttgtca cggactttta tctatgataa agttaaagag acgatatctt
   104581 ttgggaagga ggctgcgata tgtataattt aattttggga atcgtgatcg ttttatcgat
   104641 tgttatggtc attgcgatta tgatgcagcc aagcaagcaa aatagtgcag cgagtgcatt
   104701 taccggcggt gcggatcaac tattcggcaa acaaaaagct cgcggctttg aagctgtcat
   104761 gcagcgatca actgcagtta tgggagctat ctggatgatc ttattatttg tcctagcata
   104821 tttatcttcg aagtagttga ataagcctct cgcaaaacgg cgggcggctt tttttattgc
   104881 aaagagaacg cttaagaaga agttatgaaa gaaactatgg taaaatgagg cgaaagaggt
   104941 gagacgagtg agacaattac caaaacccct ttatgcaaaa catggaaagc gagcggtttt
   105001 gctgcttcac gcttactcag gaagtccaaa cgatgttcga atgctcgcac gatttttgga
   105061 aaaagcagat tatacagttt atgcgccgct ttttaaagga cacggaacaa tggagccata
   105121 tgatattttg caagaaaaag cagaaagctg gtgggcagac actaaaaaag ccatccattt
   105181 tttacagtct gagcagtttt ctgatattgc cgtattagga ttatcaatgg gcggcatctt
   105241 tgctgtacga gcactagaag aagaatcagt gattggcggc ggttttttct gttcgccttt
   105301 gtctcctgta aaaacaaacg tgcctgaaaa ctttgaaaaa tacgtacgtc aagtgctgaa
   105361 gacagcaggt aaatcagaga aagaaatcaa tgaaaaagca gttgcttacc gctcgttagc
   105421 tgaacaacaa ttaatggata tacaagatca ggcagcaatc gtagaaagta ggttgtcaga
   105481 tatccaacag ccgatatttt tagctcaagc tgggaaagat gaaatgatcg accctaatgg
   105541 cgtatttgaa actgcacgca agttgagccg tcagcgagtg acacttcgat ggtatcctga
   105601 aagtggtcat gtgattacag ttggtacagc aagacgcgaa ttagaaaaag acgtcttgga
   105661 atttttagaa aaattacctt ggaatgagga ataaatatga caaaagaaac gataaaagag
   105721 aaaattctct ttttcatgga aagcagtcgc aaacgcagtt tttctatgga agaaatcgct
   105781 gaaggtttag ggttccaaaa aagcgatgat tttaaattac tagtacaaac gattgctcaa
   105841 atggaaagag aacagagtat agttttcaat aaaaaaggaa aagtgaaact tcctttaaaa
   105901 ccaatcttga tcgaaggaac atttcgagca aatgaacgag gatttggatt tgtaacgatt
   105961 gatcccgaag aagatgacat ctatatccca aaagaagcga ctggttttgc aatggatgga
   106021 gacaccgtag caatcgatat catgaagcga gcaaatacag atatggatcg cggagcagag
   106081 gggaaagtag tcgagattcg agaccgggcg actactcagt tagcagggga attcgttgct
   106141 tattcagaag aagaaataca agaaacggat ctttacggcg ttgttatccc gaaagataga
   106201 aagctcaacc aatttaaagt atatgcagca gcagagggag ttcgtccagt tgacggaagt
   106261 attgtgctga tcgaactgac ccattaccct gaaaaagggt atgcgactag tttagaaggg
   106321 ataatcaagc aagtgattgg tcataagaat gaccctggca tggatatcct ctcaattgtc
   106381 gtggctaatg gtatccctac gaaatttcct gatgatgtat tgtctgaagc agatgaagtt
   106441 ccagatcaaa tcagcgaaaa ggatataact ggacgtagag atttaagaaa tcagctcatt
   106501 gttacgattg atggagaaga tgcaaaagat ctagatgatg cagttacggt taaaaaatta
   106561 gataacggta attattttct tggagtacac attgcagatg tttcttacta tgtgacacaa
   106621 ggcagtcaat tggacagaga agcatatgaa agagggacaa gtgtatattt gactgatcga
   106681 gtgattccga tgatcccgca acgtttatcg aatggtatct gttcactgaa tccccatgtt
   106741 ccaaggctga ccatgagttg cgaaatggag attgatccaa atggacaagt agtctctcat
   106801 gatattttcc caagtgtgat ccaaacaaca gaacggatga cctacacagc tgtcaatcaa
   106861 atcttagaag atcaagacga agaaacgatg caacgctatg ctcagctcgt acctatgttc
   106921 caagaaatgg gtgaattgca tcgaatcctt gaaacgatgc gaatcaaacg tggcgcgatt
   106981 tcttttgagg atcgcgaagc aaaaatcctt gttgatgctg aaggacaccc aaatgatatc
   107041 cagctaagaa gcagaggaat tggtgaacgc ttgatcgaat ctttcatgct tgcggccaat
   107101 gaaacggtag ctgaacatta taataaatta aatctgccgt ttatttaccg aatccatgaa
   107161 cagccaaaag aagaaaaaat gcagcgcttc tttgattttg cttcagcttt gggcattctg
   107221 gtccgaggaa cgaaaggaac gatcacacca aaagatttac agcatgtgat cgaaggagta
   107281 gaagacaaac cagaagctgc agttatcaat actatgttgc taagaagcat gcaacaagca
   107341 cgctattcag aagacaattt tgggcattat ggcttagcgg cagattacta cacacacttt
   107401 acatctccta ttcgacgcta tcccgatcta atcgtccatc gtctgatccg ttcttacagt
   107461 gaagataaaa gtgaaagcaa tcaaagttcg tgggctacgg aacttcctga aattgcagat
   107521 catagttcta agatggaacg tcgtgcagta gaaacagaac gtgaagtaga ttccatgaag
   107581 aaagcagaat tcatgatgga caaagtgggg gaagaattcg atgggatcat cagctctgtt
   107641 gtgaaattcg gcctgtttat cgaactgccg aatacagtag agggattgat ccatatcaat
   107701 gaattgaaac aggactactt ccattttgtt gaaaatcatt tagctcttgt aggtgaaaga
   107761 actggtctga cttttaaaat cggacagaaa gtgcgagtaa aagtagtcaa agctgatcca
   107821 gatgaacgag cagtagattt tgaacttgtt tccgcagaag aggttacagc gttggaacgg
   107881 ccaaaaacac gaaatggaaa atcaggaaaa cgcgaaggaa aacaagcagg aaaacgccca
   107941 gaaagaaatg gcaagaagaa caaacgatat agcgatagta agcaaacgtt cggtaagaaa
   108001 aaagggaaga agccatttta caaaggtgtt aaaaagaaga aaaagaaaaa ataaaatgag
   108061 ttggaggaaa cagctatgcc aaaaggcgag ggaaaattaa ttgcacaaaa caagaaagct
   108121 cgccatgatt attcgatcat cgacacgatg gaagcaggga tggtcttgca aggaaccgag
   108181 atcaagtcga tacgaaacag ccggatcaat ctaaaagatg gatttattcg cgtccgcaac
   108241 ggagaagctt tcttgcataa tgttcatatc agtccttatg aacaaggaaa tatttttaat
   108301 catgatccgt tgcgcacgag aaagttatta ttacacaaaa aacaaatcat ccggcttgaa
   108361 aatgaattga aaaatactgg aatcactgtt gttcctttaa aagtctatat tcgtaacggc
   108421 tatgccaagg tattgattgg tctggcgaaa gggaaaaaat cttatgataa acgggaagat
   108481 ttgaaacgaa aagatatcga tcgacaaatt gatcgaacat taaaaaattt ctctagataa
   108541 tttcattatc ctttttcgca tattcggtgc ttttgctttt acttaatgat aaaatttgtt
   108601 agcatttaat ctgataaaac atgattatca taggtttttt cttagatcag gagcaccgtg
   108661 tataaagaaa aattcgcttc gtttttgact gaaataaaaa agtgtctaat tttcatgaaa
   108721 atgttttgaa ttttctgttt catggtggta tgataccgtg tggttagaaa ccgattggaa
   108781 aaaaccagat acgcacatga attgatttta tgtgaatttc ggggaaaaga ggtgaaatgg
   108841 attggatgaa cgctcgctaa cgttccacat tggaccaatt tggtttgatg gtacagtttg
   108901 tataatggtg ttactgacct gtttgattgt tttcttctta gcttactttt ttacaagaaa
   108961 tcttaagttg aaaccaacag gcaaacaaaa tgcgatagaa tgggtcattg attttagtcg
   109021 aggaatcgta acagataatc tgcctagaaa agaattgagc aatttccatt tgttggcatt
   109081 tacattgttt ttatttgttt ttgttgcaaa caacatcggt ttagtaacaa aaatcgtttt
   109141 acctaacgaa acaacacttt ggaaaagccc gacagcagac ccgtttgtta ctttaacttt
   109201 ggcatttata atgatcttac ttactcactt atttggggtg aaaaagttag gcttcaaagg
   109261 atatttcgta aattcgttct tgaaaccata tagttttatg tttccgatga aactgattga
   109321 agaatttaca aacttattaa cacttgcttt acgtctttat gggaatattt atgcggggga
   109381 agttttgcta accttgattg caaaaatggt aataagctta ggctggttct cattgccgtt
   109441 agcaattcca ttagagatgg tctggatcgc attctccttg tttatcggaa gcatccaagc
   109501 atttgtcttc gttactttat ctatggttta tatgagccat aagattgaag tggaagaata
   109561 atattcgttt taaaaacaaa ctactattta tctaatttag gaggaaaaca attatgaatt
   109621 atatcgcagc agcaatcgca atcatgggag cagcaatcgg agccggttat ggtaacggtc
   109681 aagttatctc taaaacaatc gaatcaatgg ctcgccaacc tgaaatgtct ggtcaattcc
   109741 gtacaacaat gtttatcggg gtagctctag tcgaagctgt tcctatctta ggggtagttg
   109801 tcgccttgat tctagttttt ggtgtttaat tgaatcagta ttaaggcaga aacaatttgg
   109861 tttgttactg cttttttaca tgaaaactag aagtacttca aagaaaggaa ggctcgccta
   109921 tgctgaatca attggcaatt gcagaagttg gcaatgcgat gttaggaaat gtcatcgttg
   109981 tcagcggctc atttttgata ctactggctc tcttgaagca ttttgcttgg ggaccaatca
   110041 gcgatatttt gaaaaaacgt gaagacaaga tcgccaatga tttggattct gcagaacaat
   110101 ctcgcatcaa ctcagcgaaa atggaacaag aacgcgaaca acaattgtta gcctctcgtt
   110161 ctgatgcagc tgatatcatc aaaaatgcga aagaaagtgg agaattaagc cgccaaaata
   110221 ttttgaagga tgctcaagaa gaagcagctc gtctaaaaag taaagcccaa gctgatatca
   110281 ctgtagaacg tgattcagcg ctgaactctg taaaagacga tgttgcagaa ctatctcttc
   110341 aaatcgcgga aaaaatcttg aacaaagaat tatctccaga aatgcacgaa tcattaatca
   110401 atcaatatat cgaaggtcta ggttcttcaa atgaaactag ataaatatac agtaggaaga
   110461 cgttacggga aagctttatt tgaactggcg atcgattcaa ataaagcaga agaaatttat
   110521 caagatctcg taagcttacg tcaaatctat gaacaagtac ctggattagg taatatgtta
   110581 agtgatgttc gtctagaacc tcatgaaaaa cgagaaatca tggacaagct tgttagtggc
   110641 tatgatggaa tcgttaaaaa ctttttagaa gttgtttatg cgtataaccg aatggatgat
   110701 cttttgttca tgatcgaaga atatgaacgt cgatatgatg aacatcaagg tttgctgttg
   110761 ggaagtgtca caacagcagt tccactttca gacgaacaac gaatacaatt agaaaagaat
   110821 gttgcaaaaa caatgaacta tcaatcagtc gaattaaaac aaatcgttga ttcttctatt
   110881 attggtggcg cgattgttga agctaaccat cgagtaatcg acggaagcat tcgcacgcaa
   110941 ttagaaaata tgcgtaatca attaaataga tagtacaaag aggtaggtga atcgaatggc
   111001 catcaaagca gaagaaatta gtgccttgat taaagaacaa attgaaaatt atcaaaacgt
   111061 gctttcagtc gaagaaatcg gtaccgtaac ttatgtaggt gacgggatcg ctcgtgcaca
   111121 tggtttagaa aacgcgatga gtggtgagtt gcttgaattt tcaaatggct catacggaat
   111181 ggcgcaaaac ttagaatcaa atgatgtagg tatcattatc cttggcgatt tcgagtccat
   111241 tcgtgaagga gataaagtaa aacgaacagg aaagatcatg gaagttccag ttggagaggc
   111301 cttgattgga cgggtagtta atccgctagg tcagccaatt gacggactag gtgaaatcgt
   111361 tactgacaaa gctcgtccag tagaagcaat ggcaccaggc gttatgcaac gtaaatctgt
   111421 taacgaacca atgcaaacag gtctaaaagc aatcgacgct cttgtaccaa tcggacgcgg
   111481 ccaacgtgaa ttagttatcg gtgaccgtaa aacagggaaa acttccattg cgatcgatac
   111541 gatcatcaac caaaaaggtc aagatatgat ctgtatctat gtagcaatcg gacaaaaaga
   111601 ttctacagtt cgtacacaag ttgaaacatt gaaaaaatat ggcgcaatgg attacacaat
   111661 cgttgtgaat gccggtgcgt ctcaaccagc gccgttgctt tatatcgcac catatgctgg
   111721 tactgcaatg ggtgaagagt tcatgtacaa cgggaaacat gtcttgatca tttttgatga
   111781 tctttcaaaa caagctgttg cttatcgtga actttccttg ctgcttcgcc gtccaccagg
   111841 tcgtgaagct tatccagggg atgttttcta cttacactca cgcttattgg aacgtgcagc
   111901 aaaattaagt gatgatttag gtggcggttc aatgactgcc ttaccatttg ttgaaacaca
   111961 agctggagat atctctgctt atatcccaac aaacgttatt tcgatcactg atggacaaat
   112021 cttcttagaa agcgacttgt tctacgcagg tactcgtcca gcggttgatg ccggactatc
   112081 tgtatctcgt gtagggggtt ctgcgcaaat caaagcaatg aaaaaagttg ctgggacttt
   112141 acgtctagac ttagcaagtt accgtgaatt agaagcattt acacaattcg gttctgactt
   112201 ggatgcagca acacaagcaa aactaaatcg tggacgccgt acagtagaaa tcttgaaaca
   112261 aaaattgcat gcaccgctag ctgttgaaaa acaagtagtg attttgtatg ctttgacaca
   112321 tggattctta gatagtatcc ctgtagacag tattttagac ttcgaacatg aattattcga
   112381 atatctggat accaatcatt cagatatctt tgaaacaatc cgtacaacaa aagatcttcc
   112441 agaagaagaa gcgttgaaca gtgcgattca ggaatataaa gacatgttct tagctacaaa
   112501 aggaaataat tcctctacag aagataaatt gaaatccatt caaaatgcat agtgaggtga
   112561 gatgaatggg tgcttcatta aatgaaatca agacacgtat cgcttcaacg aaaaaaacga
   112621 gccaaatcac gcgggcaatg cagatggtgt ctgcttctaa gttgacaaaa tctgaagctt
   112681 cttcacagaa gtttcaggtt tatgcaacaa aagtaagaga aatcgttacg catttgactg
   112741 ctactcagtt aaatgatatt gcctcagaaa atcctagagg ggatatcaat tacaacagca
   112801 tgttgctcag ccgtcctgtt aagaaaacgg gttatatcgt catcactgca gatggcggtt
   112861 tagtcggtgg atataacagc tcgatattga aacaaacgat gtctatttta gaagaagacc
   112921 accaatcacc cgatgattac gtgatgatcg caattggcgg aactggtgca gacttcttta
   112981 aagcacgcgg tatcaatcta gcatatgagc tgcgcaatct atctgatcag ccaagctttg
   113041 atgaagtccg caaaatcgta aatatggcaa caactatgta ccaaaacgaa gtattcgatg
   113101 aattatacgt atgttataac catcatatca attcgctaac tagtcagttt cgtgtagaaa
   113161 aaatgctgcc aatctcagac ttagatccag aagaagcaac tactttcgaa caagaatata
   113221 tttttgaacc ttcaaaagaa gaaatcttgt ctcagttatt gcctcagtat gctgaaagtt
   113281 tgatctacgg tgcgatcgtt gacgccaaaa cagcagaaca tgctgctggt atgacagcaa
   113341 tgaaaacagc aactgataat gctgctaata tcattgatga gctgacggtt tcttacaacc
   113401 gtgcaagaca aggggctatt acccaagaaa ttaccgaaat tgttgccgga gcttcggcac
   113461 tagaatagta ttgagattgg aggaaaaaag atgagttcag gcaagattgt tcaagtaatc
   113521 ggtcccgttg tcgacgtgga attttcttta gaccaatcct taccagatat caacaacgca
   113581 ttagttgttt ataaaaatga cgaaaataaa tcaaaagttg ttcttgaagc agcgttagaa
   113641 ttaggggacg gagtgatccg gaccattgcg atggaatcaa cagatggttt acaaagagga
   113701 atggaagtca ttgatacagg caaagcaatc tctgttcctg taggtaaaga aacattaggt
   113761 cgcgtattca acgtactagg agatacgatc gatttagaaa cacctttccc agaagatgcg
   113821 gaaagaagcg aaattcataa aaaagcacca gcctttgacg aattaagtac aagtacagaa
   113881 attttggaaa cagggatcaa agttatcgat ttgcttgccc catatttaaa aggtgggaaa
   113941 gtcggactat tcggtggtgc cggtgttggt aaaaccgtac tgatccaaga actgatccat
   114001 aatatcgccc aagaacatgg tggtatttct gtatttaccg gtgtaggtga acgtactcgt
   114061 gaaggtaatg acttgtatta tgaaatgaaa gattcaggag ttatcgaaaa aacagccatg
   114121 gtgttcggac aaatgaacga accaccaggt gcacgtatgc gtgttgcttt gactggtttg
   114181 acgattgcgg aatatttccg tgatgtagaa ggtcaagatg tactgttgtt tatcgacaac
   114241 attttccgtt tcactcaagc tggatctgaa gtatcagcct tgttaggacg gatgccttct
   114301 gcggttggtt atcaaccaac attggcaaca gaaatgggtc aattgcaaga acgtatcaca
   114361 tctacgaaaa aaggttcgat cacatcgatc caagcaatct atgtgccagc cgatgactac
   114421 actgacccgg cgccggcaac agcattcgcc catttggatg cgacaaccaa cttggaacgt
   114481 aaattaacag aacaagggat ttatccagcg gtagatccat tggcttcttc ttcaagtgct
   114541 ttagcacctg aaatcgtggg agaagaacat tataaagtag caacagaagt ccaacacgta
   114601 ttgcaacgat atcgtgaatt acaagatatc attgctatct taggtatgga tgaattatcc
   114661 gatcaagaaa aagtgttagt ttctcgtgcc cgcagagtcc aattcttctt gtcacaaaac
   114721 tttaacgtgg ctgaacaatt tactggtctt ccaggttcat atgtccctgt agaagaaaca
   114781 gtgaaaggat tccgcgaaat cttggaaggc aaatacgatg atcttcctga agaagctttc
   114841 cgaagtgttg gccgaatcga agacgtcgta gaaaaagcga aaacactagg ctactagaaa
   114901 ggggtgcccc atggatcaat atttaacagt aaatgtggta actcctgccg gtttggtcta
   114961 tgatcaccat gcagctatcg tcgttgcacg tacgacagct ggtgagcttg ggattttgcc
   115021 taaacatgca ccaatcatcg ttccattgac gattgatgaa gttcgtgtaa aacgaacaga
   115081 ttcagatacc cacgtcgatt ggatcgctgt taatggcgga atcatggaag ttcgtgataa
   115141 tgttgtttca atcgttgctg atagtgcgga acgtgaacgt gatatcgatg tatctcgtgc
   115201 ggaacgtgca aaacaacgcg cagaacgcca aatcgaagaa gcaaaagcaa aacaagatac
   115261 gaacgaattg aaacgggcaa ctgttgcgtt gcaccgagca atcaatcgta tcaaagtatc
   115321 taagcactca taaaatgaga tgcggatgtt tatccgtgtt taagaacagt aaaaagaggt
   115381 tatgacagaa gtggtcagct tcaagacata agaaggaatt tacgaaaatt gcttctcaaa
   115441 tttttgtgaa atctcagctt atttttcgaa gaagctactt ctggaacacc gtatatcgga
   115501 ggttgtgaaa tcagcgtttt gtcctgagta ttagagaaac aaatggaaaa tagttcctca
   115561 tattttgccg ttttttgagc taataccgag ggtcagatga ttgaacaccg tttatttgga
   115621 ataagggact gcgacaagac ttttgtctca gtcccttttt ttgcatattt ttagcattta
   115681 tttcctaaaa aatgtaaggg gattcctata tttttaagta tacttgtttt tccttttata
   115741 cattttatgg tattatcatt ttattagtta ttataaaaca atcgttagaa aggacgtcat
   115801 tatgcaagta tacggaattg atgcggtgct tcgaatcgtg agtcatttgg cgtttatcta
   115861 cttagccttc tggtctttac gttcgttacg cattgaaact tttttcagac caatgcataa
   115921 tacgcaaatt agaatggcaa tcgtactttt ttcaattttt ttagggtaca ctgcaagtaa
   115981 ttttttctta gaagttatcg ctttatgccg aaatcttttc gttagcctgt aaattttaaa
   116041 aaaaggtact attttaaaag caaggatgtt ataatagaaa agattttgag taagtgtatg
   116101 ctcattggaa ttttttggag ggaacaacat ggaagagatc atcgtaagag gtggcaatca
   116161 attaaatgga acagtaagaa ttgaaggagc taaaaatgct gttttgccta ttttagctgc
   116221 tagtttgtta gcagaagaag gtattacgac attagacaac gttccgattc tttctgatgt
   116281 cttcactatg aatcaagtga ttcgtcactt aaacgtagat gtagattttg atgaacaaaa
   116341 gaatcaagta acaatcgatg cttcaagaca attagaaatc gaagcgcctt atgagtatgt
   116401 tagtcaaatg cgtgcttcaa tcgttgtgat gggtccgcta cttgccagaa atggacatgc
   116461 aaaagtagct atgcctggtg gatgtgcgat tggtaaacga ccaatcgatt tgcatttaaa
   116521 aggatttcaa gctttaggag caaaaattat tcaaaaaaac ggctatatcg aagcaattgc
   116581 ggatgaattg atcggtaaca cgatttattt agatttccct agtgtaggtg ctactcaaaa
   116641 tatcatgatg gctgccgtaa aagcaaaagg aacaaccatc attgaaaacg tagctcgcga
   116701 accagaaatc gttgatttag caaacatttt gaataaaatg ggcgctcaag tctatggagc
   116761 tggtactgaa acaatgcgta ttgaaggcgt ggatcattta catgcagtca accactcaat
   116821 cgtacaagat cgtatcgaag caggtacctt tatggttgct gctgcaatga cacaaggcaa
   116881 tgtgctgatt gcagatgcta tctctgaaca taaccgccca ttgatttcta aattgatcga
   116941 aatgggtgca gaaatcattg aagaagaagg cggagtccgt gtcatcggac caaaacatat
   117001 cttacctaca gatgtaaaaa cgatgcctca tcctggtttc cctacagata tgcaagctca
   117061 aatgacagct atccaattag ttgcagaagg tacaagtgta gtgactgaaa cagtgtttga
   117121 aaatcgtttc caacatttag aagagatgcg ccgtatgaac gctcatgtca aaatcgacgg
   117181 aaatgtagca atcatggatg gaaaccatga attgcaaggt gcagaagtat atgcaacaga
   117241 cttgcgggca gcagcagcat tagttttagc tggcttgaaa gcaaatggaa tcacacgtgt
   117301 gcgtaacttg aattatctag accgtggata ttataatttc catatcaaac tacagcaatt
   117361 aggtgcagac gttgaacgtg tagacatgga tcaaacttct gctgaaaaaa cagcacaaac
   117421 gattgcttaa ggaagtggct gaatgagtaa ccaacgatat atcttattaa ctttgataaa
   117481 gattttagtg gtgatcttat tgcttatcct tctttttgtg gccggaacga tgatcggata
   117541 tggtgtcatc ggtggcggca atccatttaa agtattccag ccaagtttgt ggattcatat
   117601 tcgagacttt tttcattgat aaataagaat cacagtggtt ctagtcgata tgaagtgagc
   117661 catgaagcag aacatgacaa aagaaaacag aagggaacgt tgacgttagt cgcgatccct
   117721 ttttttagta aaagaaaaga aggaatctaa ttgatgaaga agatattgat ttatttagtt
   117781 agaggatatc agcgctttat ttcgcctgca tttccaccta gctgccgtta ttacccaacc
   117841 tgttccaatt atatgataaa agcaattcaa acccatggtg cactaaaagg gacggtaatg
   117901 gggactgcac ggatcttacg ctgtcatcct tttgtcaaag gcggtatcga ttatgtacca
   117961 ttgacattcc aattaacgcg aaataagaaa gataaaaaag aaccagatta taaaaaggtt
   118021 gtgaaaaata cgagtagcac tgagcgataa agaaacaatt tggaaaatag cttcttatat
   118081 tttgcaaaat tgtgagttat tgccgaagtg ttggattttg aacaccgtca aaaaaaggtt
   118141 gtgaaaaata cgggtagcac tgagcgataa agaaaaagag gaaaattatt gtcaaagtaa
   118201 caactccgca actacttata tgggggacaa aaaatgatcg aagaactaaa caagaaagat
   118261 ttaccatggt ccttgttatt agatgcagat cctgataaag aaaaagttca agtatatgtt
   118321 tccagaggga gtggctggat atggaaagaa aaagaaaaaa caataggtgt actgatctat
   118381 gtggcaaggg aaaaagaata cgaaatcgtc aatgtagcag tagccccaac gtatcaagga
   118441 aaggggattg gcggaaaatt acttgagaca gcttttcaga agctttcaca actcgcttcc
   118501 agtcaaactc agatcatcat acgaaccggc agtactagca gtgcggcgtt acatctctat
   118561 caaaaaatgg gctatgtgga gattggtcga gtcaaagact attttatcca tcattactct
   118621 gagcccattt ttgaaaatgg agatcaatta agggatcaag taattttagc aattcactta
   118681 cctaaaaata gctttaacta ataaactttc aattcgagaa aatgctttca aatgctaaat
   118741 agatacatta caatagcttt agcaaacaaa aaggagaata tttttatggg aatattagtt
   118801 tttgattttg gtggatcggc tgtcaaatat ggttgttggg atggcaaaga gattaaaggt
   118861 aagggacaat ttgcaacgcc tgaatcttgg gaagaaatga aagcgcaatt atttcaagtt
   118921 tataaaaaaa tactcgtttc ttttgaagtc gaaggaattg gaatcagctc tcctggagta
   118981 gtgaataatg agaaacaggt gattgaggga atcagtgcga ttccttatat tcatggattt
   119041 aatattttcc gagatttgga aactctgttt caactcccag taacgattga aaatgacgcc
   119101 aactgtgccg gaatggctga attttatgaa ggtgctgccc gtgattatca agatgttgct
   119161 tttgttgtgg caggaactgg gattggcggg gcgttgttca cgaaaggaca aatcaataaa
   119221 ggggcacatc tttatggtgg agaatttggg ttgatgttct taaatggcga taagacattc
   119281 agtaaacttg gtacagcggt acagatggct tggcgttatt gtgaacgcaa aggtctcgat
   119341 aaaaattctt ataccggaaa agatgtcttt gaattagcag aaactggaga tgcaatagca
   119401 aaagaagaag ttgagagttt ttatacgtat cttacaaagg gattattcag tattcaattt
   119461 tcgtttgatc cagaagtgat cgtattaggc ggcggtgttt ctgcaaaaga agggctcatt
   119521 gatgagatca aaagccgaat gaagaagctg acagaacaat tcgatctgca tgatttcgaa
   119581 ccgcagattt tattatgtga atacagaaac gatgctaatc ttgtaggtgc agcagcaaac
   119641 tatctcgctg tacgtcaagg ggagaattaa gagctttaga gaaggtgcag cttgcataaa
   119701 agaagtgaat gaaatgaata ggagattttt acctaaggaa tgttttattt gctgcagtat
   119761 gataaaatat ctgagaggtg aaaatgatgt caaaaaaaaa taaagatgtt gaagtgcgta
   119821 tagaagaagt gaaaaaagat atcaaaggta agaattatga agtcactcag ttatttatag
   119881 ggaaaaaaat gattggtgag atcttagcct atgggccaaa agaatatgaa attttctttg
   119941 gtgaagaaga ttttggaaaa gaaaaaagtc ttgaaaatgc gatagaaaca gtgattcgac
   120001 actggaatct gcacgaataa aaaaatatca aaaaaacttt caataaaggg ttgcaaaaat
   120061 ctggaaaatt aggtattata actaagtcag gttgatacaa acctttcgga ggagtagcga
   120121 agtggctaaa cgcgacggac tgtaaatccg ttccttaggg ttcagtggtt cgaatccact
   120181 ctcctccatt tcattggggt atagccaagc ggtaaggcaa gggactttga ctccctcatg
   120241 cgttggttcg aatccagcta ccccagtata ccacaatcgt aagctctcgt tagttcgaga
   120301 gctctttttt ttgctttgct accttgttcc ttgaagattc t
//
LOCUS       DAXQKX010000002       103013 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.002, whole genome shotgun sequence.
ACCESSION   DAXQKX010000002 DAXQKX010000000
VERSION     DAXQKX010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 103013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 103013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..103013
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.002"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(31..2727)
                     /locus_tag="ACF3MF_000127"
     CDS             complement(31..2727)
                     /locus_tag="ACF3MF_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFE3926161.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(3155..4228)
                     /locus_tag="ACF3MF_000128"
     CDS             complement(3155..4228)
                     /locus_tag="ACF3MF_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFE3926162.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(4225..5052)
                     /locus_tag="ACF3MF_000129"
     CDS             complement(4225..5052)
                     /locus_tag="ACF3MF_000129"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFE3926163.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(5053..5859)
                     /locus_tag="ACF3MF_000130"
     CDS             complement(5053..5859)
                     /locus_tag="ACF3MF_000130"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFE3926164.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(5871..6956)
                     /locus_tag="ACF3MF_000131"
     CDS             complement(5871..6956)
                     /locus_tag="ACF3MF_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3926165.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(6973..7515)
                     /locus_tag="ACF3MF_000132"
     CDS             complement(6973..7515)
                     /locus_tag="ACF3MF_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFE3926166.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            7773..8762
                     /locus_tag="ACF3MF_000133"
     CDS             7773..8762
                     /locus_tag="ACF3MF_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HFE3926167.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            8759..9496
                     /locus_tag="ACF3MF_000134"
     CDS             8759..9496
                     /locus_tag="ACF3MF_000134"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HFE3926168.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNCLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEETQSKSEIAALITEKIRLEESK"
     gene            9493..10044
                     /gene="coaC"
                     /locus_tag="ACF3MF_000135"
     CDS             9493..10044
                     /gene="coaC"
                     /locus_tag="ACF3MF_000135"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HFE3926169.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            10060..10692
                     /locus_tag="ACF3MF_000136"
     CDS             10060..10692
                     /locus_tag="ACF3MF_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFE3926170.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            10777..11424
                     /locus_tag="ACF3MF_000137"
     CDS             10777..11424
                     /locus_tag="ACF3MF_000137"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding oxidoreductase"
                     /protein_id="HFE3926171.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            11429..12412
                     /locus_tag="ACF3MF_000138"
     CDS             11429..12412
                     /locus_tag="ACF3MF_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HFE3926172.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMKANKNIGKIILKITE"
     gene            complement(12815..14329)
                     /locus_tag="ACF3MF_000139"
     CDS             complement(12815..14329)
                     /locus_tag="ACF3MF_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HFE3926173.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            14467..15273
                     /locus_tag="ACF3MF_000140"
     CDS             14467..15273
                     /locus_tag="ACF3MF_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926174.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(15448..16017)
                     /locus_tag="ACF3MF_000141"
     CDS             complement(15448..16017)
                     /locus_tag="ACF3MF_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFE3926175.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(16100..18160)
                     /locus_tag="ACF3MF_000142"
     CDS             complement(16100..18160)
                     /locus_tag="ACF3MF_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HFE3926176.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            complement(18437..19915)
                     /locus_tag="ACF3MF_000143"
     CDS             complement(18437..19915)
                     /locus_tag="ACF3MF_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3926177.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(20213..21148)
                     /gene="murB"
                     /locus_tag="ACF3MF_000144"
     CDS             complement(20213..21148)
                     /gene="murB"
                     /locus_tag="ACF3MF_000144"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HFE3926178.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(21221..22140)
                     /locus_tag="ACF3MF_000145"
                     /pseudo
     CDS             complement(21221..22140)
                     /locus_tag="ACF3MF_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family protein"
     gene            22253..23005
                     /locus_tag="ACF3MF_000146"
     CDS             22253..23005
                     /locus_tag="ACF3MF_000146"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HFE3926179.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            23991..24524
                     /locus_tag="ACF3MF_000147"
     CDS             23991..24524
                     /locus_tag="ACF3MF_000147"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HFE3926180.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(25014..25538)
                     /locus_tag="ACF3MF_000148"
     CDS             complement(25014..25538)
                     /locus_tag="ACF3MF_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HFE3926181.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(25531..26004)
                     /gene="tsaE"
                     /locus_tag="ACF3MF_000149"
     CDS             complement(25531..26004)
                     /gene="tsaE"
                     /locus_tag="ACF3MF_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HFE3926182.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(26127..27107)
                     /gene="pta"
                     /locus_tag="ACF3MF_000150"
     CDS             complement(26127..27107)
                     /gene="pta"
                     /locus_tag="ACF3MF_000150"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HFE3926183.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(27260..27940)
                     /locus_tag="ACF3MF_000151"
     CDS             complement(27260..27940)
                     /locus_tag="ACF3MF_000151"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFE3926184.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            28066..28935
                     /locus_tag="ACF3MF_000152"
     CDS             28066..28935
                     /locus_tag="ACF3MF_000152"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFE3926185.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            28961..29476
                     /locus_tag="ACF3MF_000153"
     CDS             28961..29476
                     /locus_tag="ACF3MF_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HFE3926186.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(29523..30086)
                     /locus_tag="ACF3MF_000154"
     CDS             complement(29523..30086)
                     /locus_tag="ACF3MF_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFE3926187.1"
                     /translation="MIRFARKEDAPEIAPLILVILKDMELPFLKQTGEQKTLEILEEA
                     ITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKYQLDASTRLFI
                     DKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLSVDEKNPKAKK
                     LYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(30141..30320)
                     /locus_tag="ACF3MF_000155"
     CDS             complement(30141..30320)
                     /locus_tag="ACF3MF_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926188.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(30397..30906)
                     /locus_tag="ACF3MF_000156"
     CDS             complement(30397..30906)
                     /locus_tag="ACF3MF_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926189.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(31002..31382)
                     /locus_tag="ACF3MF_000157"
     CDS             complement(31002..31382)
                     /locus_tag="ACF3MF_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFE3926190.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            31712..32461
                     /gene="pnuC"
                     /locus_tag="ACF3MF_000158"
     CDS             31712..32461
                     /gene="pnuC"
                     /locus_tag="ACF3MF_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HFE3926191.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(32645..33922)
                     /locus_tag="ACF3MF_000159"
     CDS             complement(32645..33922)
                     /locus_tag="ACF3MF_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926192.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(34001..34645)
                     /gene="pcp"
                     /locus_tag="ACF3MF_000160"
     CDS             complement(34001..34645)
                     /gene="pcp"
                     /locus_tag="ACF3MF_000160"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HFE3926193.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(34844..35788)
                     /locus_tag="ACF3MF_000161"
     CDS             complement(34844..35788)
                     /locus_tag="ACF3MF_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HFE3926194.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(35790..36476)
                     /locus_tag="ACF3MF_000162"
     CDS             complement(35790..36476)
                     /locus_tag="ACF3MF_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HFE3926195.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            36950..37270
                     /locus_tag="ACF3MF_000163"
     CDS             36950..37270
                     /locus_tag="ACF3MF_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HFE3926196.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            37424..38329
                     /locus_tag="ACF3MF_000164"
     CDS             37424..38329
                     /locus_tag="ACF3MF_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3926197.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            38326..39099
                     /locus_tag="ACF3MF_000165"
     CDS             38326..39099
                     /locus_tag="ACF3MF_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFE3926198.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(39280..40704)
                     /locus_tag="ACF3MF_000166"
     CDS             complement(39280..40704)
                     /locus_tag="ACF3MF_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="basic amino acid/polyamine antiporter"
                     /protein_id="HFE3926199.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            40915..41361
                     /gene="nrdI"
                     /locus_tag="ACF3MF_000167"
     CDS             40915..41361
                     /gene="nrdI"
                     /locus_tag="ACF3MF_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HFE3926200.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(41426..43408)
                     /locus_tag="ACF3MF_000168"
     CDS             complement(41426..43408)
                     /locus_tag="ACF3MF_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HFE3926201.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(43422..44318)
                     /gene="murQ"
                     /locus_tag="ACF3MF_000169"
     CDS             complement(43422..44318)
                     /gene="murQ"
                     /locus_tag="ACF3MF_000169"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HFE3926202.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(44321..45382)
                     /locus_tag="ACF3MF_000170"
     CDS             complement(44321..45382)
                     /locus_tag="ACF3MF_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HFE3926203.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(45593..46120)
                     /locus_tag="ACF3MF_000171"
     CDS             complement(45593..46120)
                     /locus_tag="ACF3MF_000171"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFE3926204.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            complement(46187..47689)
                     /gene="eat(A)"
                     /locus_tag="ACF3MF_000172"
     CDS             complement(46187..47689)
                     /gene="eat(A)"
                     /locus_tag="ACF3MF_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HFE3926205.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(47947..49068)
                     /locus_tag="ACF3MF_000173"
     CDS             complement(47947..49068)
                     /locus_tag="ACF3MF_000173"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFE3926206.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYSLGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            49194..50135
                     /locus_tag="ACF3MF_000174"
     CDS             49194..50135
                     /locus_tag="ACF3MF_000174"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFE3926207.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(50285..51181)
                     /locus_tag="ACF3MF_000175"
     CDS             complement(50285..51181)
                     /locus_tag="ACF3MF_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HFE3926208.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            51450..52790
                     /locus_tag="ACF3MF_000176"
     CDS             51450..52790
                     /locus_tag="ACF3MF_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFE3926209.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            53008..53451
                     /locus_tag="ACF3MF_000177"
     CDS             53008..53451
                     /locus_tag="ACF3MF_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HFE3926210.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(53955..55373)
                     /gene="nhaC"
                     /locus_tag="ACF3MF_000178"
     CDS             complement(53955..55373)
                     /gene="nhaC"
                     /locus_tag="ACF3MF_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFE3926211.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(55776..56999)
                     /locus_tag="ACF3MF_000179"
     CDS             complement(55776..56999)
                     /locus_tag="ACF3MF_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFE3926212.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(57030..57869)
                     /locus_tag="ACF3MF_000180"
     CDS             complement(57030..57869)
                     /locus_tag="ACF3MF_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFE3926213.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(57886..58566)
                     /locus_tag="ACF3MF_000181"
     CDS             complement(57886..58566)
                     /locus_tag="ACF3MF_000181"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFE3926214.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(58568..59641)
                     /locus_tag="ACF3MF_000182"
     CDS             complement(58568..59641)
                     /locus_tag="ACF3MF_000182"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFE3926215.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     gene            complement(59715..59867)
                     /locus_tag="ACF3MF_000183"
     CDS             complement(59715..59867)
                     /locus_tag="ACF3MF_000183"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926216.1"
                     /translation="MDVVKFLDDADIANDPNNPPQFTCEKCGKEMYPEYYRNALGIEF
                     KISDVQ"
     gene            complement(59884..61203)
                     /locus_tag="ACF3MF_000184"
     CDS             complement(59884..61203)
                     /locus_tag="ACF3MF_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016372324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS91 family transposase"
                     /protein_id="HFE3926217.1"
                     /translation="MKANILEAIFFDEHHNWDNFVEKYGRKIRLVVKREVNKFRYCGD
                     IQKGYRLFVCEGCHQTKFVPLKCRGKFCPTCATGESQRWSAVVANDMFKVTHRHVIFT
                     IDEGLREIFMMENYRDSLLKGLMDEAAKIILAYFEKRKVKAGIVATIHTFGSKLEFNP
                     HVHMVVTMGGLTRDGSWEEYDYLPFSMLRKYWKNAVLKLIRRTLGEWDKQRVQSRLQA
                     AYKNNGEGFYVNAPKRSRTNLKSLLQYISRYMKRGPIALSRILMYDGDTVMFNYMDKR
                     TNTKETMTMSIDEFIAALIRHIQNKNFKTIRRYGIYSRRIKTLMKKVMKEYQKRVKKL
                     FINLNEALRPKSWEERITEEFGENPLECSCCGEYYEFVGMSVRKNGRLVIKYAKDNHA
                     KRFMREENRKIDQKEFRQQYEEEKEKTFKAIRWDWERQREIYMSKLW"
     gene            complement(61581..61673)
                     /locus_tag="ACF3MF_000185"
     CDS             complement(61581..61673)
                     /locus_tag="ACF3MF_000185"
                     /inference="COORDINATES: protein motif:HMM:NF013677.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFE3926218.1"
                     /translation="MPRRSFDEIFKITAVKLVTEEGFSVKEVSL"
     gene            complement(61944..62924)
                     /locus_tag="ACF3MF_000186"
     CDS             complement(61944..62924)
                     /locus_tag="ACF3MF_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HFE3926219.1"
                     /translation="MLFLKKEDIIKSFSMREAIDADKKALSLYSAGKASVPLRTNIDV
                     PKSNGQSLYMPAYVEGGEGALGVKIVSVYPENIKKNLPSVPATMIVLDPETGMVSACL
                     DGTYLTQLRTGAVQGAATELLAREDAKIGALIGTGGQAQSQLEAMLTVRKLEEVRIFD
                     IDFERASQFAEKMMQQFSVTMRPTKTSQECVEGADIITSVTTSKRATFSAEWVKKGAH
                     INGVGAYTPEMCEIPREIIKAADVVIFDTMDGVLKEAGDFISPLQDGYIQRDSYHGEL
                     GQLINEELIGRTSGEQITIFKTVGSAVLDVVVATEIVKKAKENNLGKLIF"
     gene            complement(62937..63815)
                     /locus_tag="ACF3MF_000187"
     CDS             complement(62937..63815)
                     /locus_tag="ACF3MF_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HFE3926220.1"
                     /translation="MIRNILLTLIVAINLYFIIYFLRDLFKNKQNFKEEPGDMRLLPF
                     TSFIIFFLSTFGVSDFAIGTVLYPKLKWVSMKKLPGTLNTQCVVPVAVMALSYITAIN
                     VGIKTLAVCIICQIIGAYLGPRFVVKLPEKTIKLFVGIGLVIAALLIFAGQMNWIPSN
                     GTASELYGGKLILAGFLLFVYGALNNIGIGSYALTMVTVYLLGLNPVAAFPIMMGACT
                     FSVPIGSVQFIKFNEYSRKITLFTSTFGVLGVLVAVFLVKSLDTYILKWIVILVLLYS
                     AYTMLGSQLKKVTAAN"
     gene            complement(63831..64631)
                     /locus_tag="ACF3MF_000188"
     CDS             complement(63831..64631)
                     /locus_tag="ACF3MF_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HFE3926221.1"
                     /translation="METIIQIMKKYDFSEMETRVYTTLLEKGNLTGYEVSKISGVPRS
                     KVYNILEKLLKKNLIVVNKSEPKLYHAISANEFLEKLEKSVKNDLSFLTKNLGMIKEK
                     DEEEMLWKVDGIEYVLDKVEHLVKNAKESLLIQVWHENFTDSLLKALQQAEKRVDKFV
                     LILFSSTHEYDLPLEKYYIHGFETDKLADFGARWINIVADEQEVVFGTINEELQSTDV
                     TWTKNHAMVNLAKEYVKHDAYTLKVIAESPEELKAKYGEGFEGIRKIY"
     gene            complement(64906..65055)
                     /locus_tag="ACF3MF_000189"
     CDS             complement(64906..65055)
                     /locus_tag="ACF3MF_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926222.1"
                     /translation="MKKKVIPYCPKPRNAFERGLFKYFEGKKGQDHKEENQKKKSKKR
                     SEYIF"
     gene            66023..66349
                     /locus_tag="ACF3MF_000190"
     CDS             66023..66349
                     /locus_tag="ACF3MF_000190"
                     /inference="COORDINATES: protein motif:HMM:NF013698.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFE3926223.1"
                     /translation="MFKIFRKNCCGLDVHKTWIYACIGITDANGRTVYKQARFSSFTK
                     GLNELAEWLAKYNCKDVCLESSGKFWIPVFNILEKTCFVTLAHPKYTKPQKGNKTDRK
                     DAKMDL"
     gene            66357..67265
                     /locus_tag="ACF3MF_000191"
     CDS             66357..67265
                     /locus_tag="ACF3MF_000191"
                     /inference="COORDINATES: protein motif:HMM:NF033542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFE3926224.1"
                     /translation="MCDMIKPSFIPGLEIRQLRDLMRYRTKLTNMKTSEKNRALNCLT
                     VSNLKLDDVFSDVFGKSSTSIIQYLLEHPGESFDVRPFIHARCKTPVEEIQAAVEGAI
                     SVPQAIKLRQCLNHINEIEKHREEINLEIQALAEPFSPVLELLRTIPGLDTQPITAIA
                     ILSEIGPDMSVFPTSKHFISWAGCCPRNDRSARRTKSTRISRAGQSLKPLLVQIANAL
                     LRSKEHPEFKNRYRRIKANRGHKKAIIAICKMLLTAIWNVLSKVEPYSAKGYLEPKPA
                     KEEKVLTQSQALDLLRKRGYTIIDSA"
     gene            67891..68145
                     /locus_tag="ACF3MF_000192"
     CDS             67891..68145
                     /locus_tag="ACF3MF_000192"
                     /inference="COORDINATES: protein motif:HMM:NF013224.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC ligand binding domain-containing
                     protein"
                     /protein_id="HFE3926225.1"
                     /translation="MIKSNQKSGFYTFIKAISSVLECDCIIGPYSMLIKMGFPSTESL
                     DSFINDLSKFGRTNTQIVFSTLVSLMVYQFWNVYHALLLK"
     gene            68687..68845
                     /locus_tag="ACF3MF_000193"
     CDS             68687..68845
                     /locus_tag="ACF3MF_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3926226.1"
                     /translation="MNKKQACEFLGIDNNTLDKWIRVYNFPVIKIDGVVRFDVEDIKD
                     FMNTFKKN"
     gene            68917..70143
                     /locus_tag="ACF3MF_000194"
     CDS             68917..70143
                     /locus_tag="ACF3MF_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFE3926227.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFREITGIASEKYQKVFPTRQLAIKA
                     EREMKKKIETVLREENANSLELKGKIKFKDFYESKWLPRYELGQTTRSNRAPSNVTIS
                     NTKDIFRLHILPMFGEYAMNYLNSNTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILCYIEFNRTTKIIQCITAPKKMALEEKRIREGNQALSSEELTDWIEAVNNDLNNHLL
                     TLHDYTLFMLTLYLGDRKSETYALQWKYIDFNKNTVRLKYALDKYQRKTHTKGWKDTV
                     IQAPEVVMTLLREWKSAQAEQLLKLKIIQTPDQYLFTYSKPSGEVNCPVHADYLNYRI
                     NAIKKRHPELAQLSPHKLRHTYATIAREGGANMNQISNALTHSDISTTKIYVNTPDVV
                     DKSVFEAFQKGLNKCD"
     gene            complement(70232..70624)
                     /gene="rpsI"
                     /locus_tag="ACF3MF_000195"
     CDS             complement(70232..70624)
                     /gene="rpsI"
                     /locus_tag="ACF3MF_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFE3926228.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(70640..71068)
                     /gene="rplM"
                     /locus_tag="ACF3MF_000196"
     CDS             complement(70640..71068)
                     /gene="rplM"
                     /locus_tag="ACF3MF_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HFE3926229.1"
                     /translation="MAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPTFTPHL
                     DTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLIETSVK
                     GMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(71602..72069)
                     /locus_tag="ACF3MF_000197"
     CDS             complement(71602..72069)
                     /locus_tag="ACF3MF_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HFE3926230.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(72189..73727)
                     /locus_tag="ACF3MF_000198"
     CDS             complement(72189..73727)
                     /locus_tag="ACF3MF_000198"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046316 - gluconokinase activity [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0046177 - D-gluconate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HFE3926231.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            73807..74493
                     /locus_tag="ACF3MF_000199"
     CDS             73807..74493
                     /locus_tag="ACF3MF_000199"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HFE3926232.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(74694..75221)
                     /gene="msrA"
                     /locus_tag="ACF3MF_000200"
     CDS             complement(74694..75221)
                     /gene="msrA"
                     /locus_tag="ACF3MF_000200"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFE3926233.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(75305..75982)
                     /gene="pgmB"
                     /locus_tag="ACF3MF_000201"
     CDS             complement(75305..75982)
                     /gene="pgmB"
                     /locus_tag="ACF3MF_000201"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFE3926234.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(75979..77109)
                     /locus_tag="ACF3MF_000202"
     CDS             complement(75979..77109)
                     /locus_tag="ACF3MF_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFE3926235.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(77109..79292)
                     /locus_tag="ACF3MF_000203"
     CDS             complement(77109..79292)
                     /locus_tag="ACF3MF_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 65 protein"
                     /protein_id="HFE3926236.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(79289..80314)
                     /locus_tag="ACF3MF_000204"
     CDS             complement(79289..80314)
                     /locus_tag="ACF3MF_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFE3926237.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(80359..81186)
                     /locus_tag="ACF3MF_000205"
     CDS             complement(80359..81186)
                     /locus_tag="ACF3MF_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFE3926238.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(81183..82250)
                     /locus_tag="ACF3MF_000206"
     CDS             complement(81183..82250)
                     /locus_tag="ACF3MF_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HFE3926239.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKHGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLIGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(82276..83112)
                     /locus_tag="ACF3MF_000207"
     CDS             complement(82276..83112)
                     /locus_tag="ACF3MF_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFE3926240.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(83109..83978)
                     /locus_tag="ACF3MF_000208"
     CDS             complement(83109..83978)
                     /locus_tag="ACF3MF_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFE3926241.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(84048..85331)
                     /locus_tag="ACF3MF_000209"
     CDS             complement(84048..85331)
                     /locus_tag="ACF3MF_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFE3926242.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(85345..87030)
                     /locus_tag="ACF3MF_000210"
     CDS             complement(85345..87030)
                     /locus_tag="ACF3MF_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HFE3926243.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            87305..88330
                     /locus_tag="ACF3MF_000211"
     CDS             87305..88330
                     /locus_tag="ACF3MF_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFE3926244.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(88925..92578)
                     /gene="rpoC"
                     /locus_tag="ACF3MF_000212"
     CDS             complement(88925..92578)
                     /gene="rpoC"
                     /locus_tag="ACF3MF_000212"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HFE3926245.1"
                     /translation="MIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPERE
                     GLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVS
                     HIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKRE
                     QYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRA
                     SGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNA
                     PGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIER
                     QEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADF
                     DGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEG
                     REGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKII
                     FNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNII
                     AEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVET
                     ITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISN
                     FTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPE
                     TNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVIT
                     EVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSI
                     DPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTD
                     ILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRV
                     LTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEA
                     QMAAEDAMNNQTK"
     gene            complement(92657..96274)
                     /gene="rpoB"
                     /locus_tag="ACF3MF_000213"
     CDS             complement(92657..96274)
                     /gene="rpoB"
                     /locus_tag="ACF3MF_000213"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFE3926246.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            97002..97970
                     /locus_tag="ACF3MF_000214"
     CDS             97002..97970
                     /locus_tag="ACF3MF_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFE3926247.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            97988..98893
                     /locus_tag="ACF3MF_000215"
     CDS             97988..98893
                     /locus_tag="ACF3MF_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFE3926248.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            98890..99696
                     /locus_tag="ACF3MF_000216"
     CDS             98890..99696
                     /locus_tag="ACF3MF_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3926249.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            99853..100821
                     /locus_tag="ACF3MF_000217"
     CDS             99853..100821
                     /locus_tag="ACF3MF_000217"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004077 - biotin-[acetyl-CoA-carboxylase]
                     ligase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HFE3926250.1"
                     /translation="MTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKAIKELEKA
                     GYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAKLAAAQGD
                     SVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTIIAASACVK
                     AIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLNFSVPQNH
                     FPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKSFVLGKTV
                     SFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(101138..101662)
                     /locus_tag="ACF3MF_000218"
     CDS             complement(101138..101662)
                     /locus_tag="ACF3MF_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HFE3926251.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            101949..>103013
                     /gene="scm"
                     /locus_tag="ACF3MF_000219"
     CDS             101949..>103013
                     /gene="scm"
                     /locus_tag="ACF3MF_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HFE3926252.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSS"
BASE COUNT        29889 a        21370 c        18464 g        33290 t
ORIGIN      
        1 aaaaacagat tagacacttt tttagacact ttatttttga atatacggtc ctaataattc
       61 atagagcagc gaaagctcat aagcattgac tttaaaatta tatttcatct ccattgattg
      121 aaaaatactt ctagaaacat aataaaattc atcttcatct ggtttcaaat cataattcgg
      181 ttcttcagat ttttctgtcc gagccaagaa taaacgttcc atcatcaatg ccgtatgcat
      241 atagagattt agttttacac ggccatttaa agtgaaatga tagtaatttt catatttaga
      301 aatgactgtt tccacttcac tcatcacgat cgttgggttc agaaagttca aacggtccgc
      361 aattccttcc aacgaaaaga attttactag ctcctgaatc aagcggttaa attctgccgg
      421 cttcatttca ggactcaaaa tatgctccaa attggctgct ccatcaccgt ctaagatgtc
      481 ataaacatta atattaggaa ttgaaaagga acgtggaaga tccgaagtcg tgatgaccaa
      541 ttttgtcttg tcaaaataag tttcatcatt ttggtcgatt aattcacgta gttctctgta
      601 gtccttcgtg aaaacttcga tggattcatc cgataaatga tgacgaaaaa catctttcaa
      661 tttgtccgaa atccccaaac ccgacataca ggaaatgata atgttgctac tttgagaaaa
      721 gccttcaaag tattgaacat tgattgaata cttgtctgct gcatcctccg caatctgttt
      781 aaatggcgca ttcatcgtca tcttcaagcc aatatcaagt gcaatggaag tcgtcaaatt
      841 attcagaaga agtaactccc cttttaaatc gttcttgatc tgtgtgtaaa tttgatttaa
      901 agagcccata tctacgatca gcactagact atctgtattc acttgccgtt tcacgaaatt
      961 ccttgtcgat tcgacaatct ctgacacatt actctctact ggcatatcca acgcttcaaa
     1021 aacataattg ccgcataatt gattcactac tgcttgaatg ctgctagccg tactatctcc
     1081 gtgagcaagc aacaggccct tcagctcgat ggattcatct acataatcag ataaagtcac
     1141 gacaataagc agtcttagaa agttctcgtc cttttctgag agcggtggta aatgctccaa
     1201 gaactgatta cataagtaag tcgtccgagg tagatttgca gctaatgtac gatttatccc
     1261 ggttaagtct gtcttatagc ttggggaaat gacataggat ctgctaataa tttctgcaac
     1321 aggtccactc gtcgtcaatc cgtacgtttt tcctaaaacg gatacccaga cctttctaaa
     1381 catctgaatc atcaattttc tactcattga taaaaaagaa tccttatcaa tgtgatgcac
     1441 caaatgctgt acttcattct ttatcgaaga aaaattttca ttgaaattac cttcatttat
     1501 cagctgagta attttttcca aaatcgaatc ataatcaaac ggtttgattc gatccgtttt
     1561 tatcttttga tttttcttta tcaataaact agcaatcggc aagctttcta cttcggattc
     1621 cagcatattt aactgaatca agatctcatt tttcccaatc gttaatggtt cttcttgtgt
     1681 tcgactatac acatccgcac aactgatttt aatgatattc ttcagcttac caatattccc
     1741 actaaaggga tgagataaca ttaaagacaa ggcttctctt gaaacaataa tatctttttg
     1801 taaaacatcc gcttcatttt gaaaaaataa ttgaatcagc tctaatcgtt ctcgaatggg
     1861 gcgatcttca aaagttggca acataacact aatttgaata cgccgatcaa aggtgtctaa
     1921 taaataattt tcaccttttt ccgtcgtggc gaaaataaaa cgaaccttag cagaatgcca
     1981 atttacattt tcaccgactg gacgatagtt tccagtatca ataaatagaa agagcttttc
     2041 ttgattttct ttcgataggc gatggacctc atcgagaaaa agatagccgt tgttggccgt
     2101 tgccaataaa ccatcggtat ccttttcagc ccccgtaaag gcccccttct tgtatccaaa
     2161 cagtgttgcc gaaagcagtt cgggattgtc cgcataatcg gcacagttta agatagcaaa
     2221 tggtgcatct ttttcaataa tttgctcatg gatagcgtat tcaaaaattt ttgtggctaa
     2281 aaaacttttt ccaacacccg tggctccatt tattaataca ctgagtccgt taggcggata
     2341 tttgacagcg gctatacatt tttgaatgac ctctctcaga cttccgtcat gaccaactac
     2401 agaatgaaag gcttcgttta tttgctccgt attatctaca accgcatatt catctaaagg
     2461 cttccacaaa acaggctttc ccggtaattt ctcgaccttt ttatcttcca ctaatctcgt
     2521 caaataatgg ctggcattct gacgagagat acctagattc ttcgaaattt tctcggcagt
     2581 gacagaagac atattccctg ttagtcgtat cagctcatca aaaactcgat ctttagcgct
     2641 ctttttcatt ttttcctcca gtttaatgtg tctaaaagca taataaacta tcggctgcaa
     2701 tatgtctatt ctatatttgt attccaattt ttactttgaa acacaaatag tcgaatattt
     2761 gcctcagata tctgacaaaa taatttatct accaatttag tttttatcta atatgatttt
     2821 tatgtttttt catagctaca aatattgaac tggattcata tattagtttt attaatagat
     2881 tacagaaggg ttaagtatat ttgcatagtt tccaattact ttatccttct gtaacttttt
     2941 caatcttaga tttactagcc cgtctcgggc cctattttac aatggttttg tccacttttc
     3001 tctggtagaa aaacgtggta gaaaaaataa aataacacaa aaaaagcggc gtttcatccg
     3061 cttttggtag aagattggaa aactcagata gaaaaaggac gatttttagc tctttagaac
     3121 gttgataagt ccccattctt actgagtttt gccattatct cctatacatc ttgaattcta
     3181 agaataggtc attatagatg cctaggtatt tcgatcctag atctttgtag acttcaagat
     3241 gggagatcgt gtcatcagat ggatagaatt gttcgtccga cgaaatgtct tttggcaata
     3301 acgcttttgc ttcttcattt ggtgtagaat aaccaatata ctctgcattt tgtgccgcat
     3361 tttccggttc tagcataaag ttgatgaaat cataggcacc ttctttattt ttcacggttt
     3421 ttggcataac gatattatca aaccaaagat tggatccttc tggtgggatc acataatgta
     3481 aatgttcatt ttcccacatc atatcggcag cttcgccaga aaatgtcact gccacggagg
     3541 cttcttcatt gatcatatac attttgatct catctgccac gattgctttg acatttggtg
     3601 ttaaatgatt caatttattt gctgcttctg tcagctgtgc catattctta ctattcaaag
     3661 aatagcctaa actattcaaa gaaagcccca taacttctcg tgcaccgtca atcagcatca
     3721 aactgtcttt taattccggc ttccacaaat catcccaatg cttaatttga tttgcatcaa
     3781 agaatttatc gttatatacg atccctaaag ttccccaaaa atatggaatc gaatactgat
     3841 tatctggatc aaaatccaag tctaaaaatc gtggatcaat attatttaat cctttgatct
     3901 tcgaatgatc taatggaagt actagttttt ctttgatcat tttttggatc atatattcac
     3961 ttggtatagc gatgtcgtag tttgtcccac cttgctggat ttttgtgaac atcgcttcat
     4021 tagaatcaaa tgtttcataa ttcactttgt atccatattc tttttcaaat ttcgtgatca
     4081 aactaggatc gatataatct ccccagttat agatggtaag tacctttgct ccactcatgc
     4141 cacttgtttt ttcaagttga cgaacaccaa gcagcagcac cgcaataatg atgagaatac
     4201 ctaaaaacag agattgtaat tttttcatcg cagccgtgcc accccctcgc gtactcttct
     4261 gtttttcttc agccgttttg gacggttttc tttactaata aagtagtatc caatgaccaa
     4321 tatcatggag aacaagaaaa ctaacgcact tagcgcattg atttctaaac tgattccttg
     4381 tcttgcacga gaatagatct ctactgagag cgtcgtaaag ccatttcctg tgacgaaaaa
     4441 tgtaaccgca aaatcatcaa gagaataggt aaatgccata aaatatccag ctatgattcc
     4501 tggagaaaga taaggcaaaa tgatattttt gactacttgg aaattattag caccaaggtc
     4561 tctagccgca tcgaccattg aatcgttcat ttcctgcaat tttggcaaga ccatcaagac
     4621 gacgattgga atgctgaaag caatatggga aagcaataca ctctgaaaac ctaatccgaa
     4681 tcctagtagt gtaaagaaaa tcaagaaact agcaccgata ataacatcag gagagactaa
     4741 taagatgtta ttcatgctca acaacgctgt ccgtgcacgt cgttttttcg tgtaatagat
     4801 tcccatagcc ccaaatgtcc cgatgatcgt ggcgatcaat gcagataaga aagccagcat
     4861 gaacgtattc aatacgataa tgatcaaacg tgtatcttca aaaacagctt cataattttc
     4921 ccaagtaaat cctgtaaagc tgttcatcgt tcctccttca ttgaaggaat aaaaaatcag
     4981 atagaagatc ggtgcatata agaataaaaa gacgatccct aaataaagat acgaccattt
     5041 aaattttttc atttatgagc gacctccttt tttcttctcg cctgtcagga gcatcacgat
     5101 gaacatagca atgattaaaa tcacaccgat tgtagaaccc atcccccagt tttgtgtaac
     5161 caagaaatgc tgttcgatag ccgttcctaa agtgatcacc cgatttccgc caatcagacg
     5221 agtcagcatg aataaagaaa gagaaggaat aaatactgct tggacaccac ttttcacacc
     5281 atttaatgat aacggaaaaa tcactcgtcg gaaggtctca aagctattcg cgcctaaatc
     5341 tctactagca ctgatcaaag aaggattcat ctcttccaat gcattgaaaa ttggcataat
     5401 cataaatgga atctcgatat acgttgccac gaacagaaaa ctgaagtctg tgaataatat
     5461 ctgtttcggc ccgatcccga taaaatcaaa gaaatgattc acgctgccgt gcacactgaa
     5521 aatcccaata aatgcgtaag ctttaagcag cagattcacc catgtaggca aaataatcag
     5581 catcagccat aattgcttgt gcttcagttt tgttaaaaaa taagcagtcg ggtaactgat
     5641 gatcagcgtg aaaaacgtga tcaaaaatgc ataccataca gaattgatcg tcatagaaag
     5701 cgatgtcccc gacgtaaaat aagatagata attattcagc gtgaattgcc cattcatatc
     5761 aaaaaaagat tgataaatga tcattaatac aggcgcgatc acgaataaac cgagccacaa
     5821 aatataaggg acggaataga tcctgcgcat tgttttcatt cttgtccccc ctattcttcg
     5881 tagctgtcaa gacgtgcatc gaattcttct tcagactcgt tgaaacgcat gacatggata
     5941 tcttctggct caaaggccaa tcctactttg cttccttctt tagctttttt cgttgaatgg
     6001 accatccatt cattttgctg ttcatcataa cagatgattt cataatggac accacgaaac
     6061 agctgagtat cgaccgttac gactagtttt cctttatctg gtgtcgtgat cgtcaaatcc
     6121 tctgggcgta aaacaacttc aactggttca tttagacgca tcccgccatc gacacattca
     6181 aattgcttac caacaaactc aactagatta tcttcgatca ttacaccgtc cacgatattg
     6241 ctctccccaa caaaatcagc aacgaaatga ttgattggct catcataaat atctacgggt
     6301 gtaccacttt ggacgatttt ccctttattc atgacaaaaa tctcatcact cattgccaac
     6361 gcttcttctt ggtcatgagt aacaaaaata aacgtgattc ctaatcgttg ttgcagatcc
     6421 cgcagttcat actgcatatc tgtacgtagt ttcaaatcaa gcgccgataa cggttcatct
     6481 aatagcaata ctttcggttc atttacaatt gctcgtgcaa tcgctacacg ctgtctttga
     6541 ccaccagaca tttcactaat ctcccgtttt tcgtatccag gaagctggac catacgcaaa
     6601 gcatctttta ccttcttttc gatatctgat ttggacattt tcttgatctt caatccaaaa
     6661 gcaacgttat caaaaacatt catatgagga aaaagtgcat aatcttggaa gactgtattt
     6721 acttgtcgct tattagctgg caaatcattc aaccgtttcc cttcaaaata gatgtcccct
     6781 tctgtagctt cggtgaatcc agctataata cgtaggatcg ttgttttacc acagccggaa
     6841 ggaccaagca gtgtataaaa ttttccttgt tcgatctcaa aacttacttt ttttaatact
     6901 gtttcatcat catagcgttt cactacttga tcaaatgaaa tgattggttt ccccacgttt
     6961 ttacccccta tattacaaat atgattgcgt tgcaacaatc aatacttttg ttcgtttttt
     7021 gagatgattc cttaattgat gttgttttgt cgcttgataa tagatcgact gtcctgcttt
     7081 tgccacatag accgtctctc ctaagcttaa ctctaattcc ccttctaata caaaaataaa
     7141 cgtttcagat aatgaaggtt caaacgtctt atattctcct gcaccttcaa aagtcagcaa
     7201 gacaggctcc atttcttttt cattcgaatc agccacgagc cattccaatt catacccgtt
     7261 ttcttcatcg aaataaaccg tatgatcttc ttttgaataa accacttgca gattcgctgc
     7321 ttcttgatga aaaaattctt ctggagtcac acctaagact tcaagaatag aaaagaatgt
     7381 ttccattgat ggtgaactta aatctcgttc caactgggaa atataccctt ttgacaaatc
     7441 tgtgcgttcg cctagttctt cttgtgtcaa attcttttgg atgcgcaaat ttcttaactt
     7501 ctcaccaatt tccataattt cctccgaatc gaagttttct aatagtaaac ttcctgttta
     7561 ctaccactcg tattagtata cgaaatttat tgaaaaaggc aaccctttgt aaaatttttt
     7621 ttgctgaata tttctttatc ttttggaata aattctagtt gtttgattct ttatttttca
     7681 cctaattttt gtctaaattt acggaagaac aagaataaaa gagtaggctt tatggtatga
     7741 taaaagaaaa ttttaaaagg agtgtctcac gaatgaacgc ttttcgatct tttcaggtaa
     7801 taaaggaacc tgttttccat acagcaatca gtgatctgcc atttactgag ttggctgaaa
     7861 atgaagtctt ggtaaaaatt gcctattctg atgtcaatta taaagatgca ttggcaatga
     7921 gcgagtctgg tcaggtgata cgaacatatc cgatgactcc agggattgat ttatccggaa
     7981 ctgtcgtcca aagtaacaat ccacgttttt caaaagaaga tcttgtactt gctactggtt
     8041 ttgggcttgg cgtcacccat ccaggcggtt atagccaata tcaaaaagta ccaggagact
     8101 ggttagttcc tctaccaaaa aatatgacgc tgcgtcaagc gatgatcctt ggtacagcag
     8161 ggtttactgc tatgttgtgt gtgaacgctt taatccgtca aggtatgacc tccgataaaa
     8221 aagttgtcgt tactggtgct tctggcggtg taggcagtac agcgatagcc ctgttacata
     8281 aactaggatt ccagtcaatc attgcctttt ccagaaaaga agagtctgtc acatggctaa
     8341 aaagtctagg tgctttgcaa gtcgtacgac ctgatgaatt tctgccagag acaacaaaag
     8401 ctttaggaaa acagcaaatc gactatgtca tcgacacagt aggtggcgag cagctaagca
     8461 gtcttcttcc attgatctct tataacggtg cagtagcttt atgtggcaat gctgggggaa
     8521 tcaaactaaa cgcgactgtc ttgcctttta ttctgcgaaa catccagttg attggaattg
     8581 attctgtcaa tgtaccaata gatcaacgtc tttctttatg gcaacagatg gcggatttgc
     8641 agattgcaga tgaactggtc gtccaagaga ttactctgga tcaattgcct gaaacagcat
     8701 ctaaactact tgctggaaca caccaaggaa gaacactagt aaatgtaggt gaccataaat
     8761 gaagattcta atcacagctg gaggaacgac tgaaaaaatc gatcaagtac gtgctattac
     8821 aaatcattcg acaggacgat tagggcaagc attagctgat tatttagctg ccaatccgga
     8881 taccacaatc gattacgtga ctacgaaaca agcactgaaa ccgaaaagac actccaatat
     8941 aacgatttat acgatcgaat ctgcactgga cttattttta caattagaag aactaacgaa
     9001 aaaagaacac tacgatgcga ttatccacag tatggcagtc agtgatttta ctcctgcttt
     9061 tagtttttca gaagaacagc tggcaaaaaa cctacccact tcttcaacgc aagaagaact
     9121 ggacaattgg tttgcggaaa atgaacagac agataccact gtttcaaaga tctcttctaa
     9181 caccgagcat cttgtgctcg ttttgaagaa aacaccaaaa atcatttctt atctacgtga
     9241 atggcagcca aaagcaaaaa tcattggttt caaactatta gtagatgtac caaaggaatc
     9301 tcttctggca gtcgcaaaaa attgtctgat aaataacaaa actgatttta ttttcgcaaa
     9361 tgatttgacg gaaatccatg gcgagacaca ccacggctat ctcttatcta aagatggaac
     9421 agtggaagaa actcaaagta aatctgagat tgctgcattg attactgaga aaattagact
     9481 ggaggaatca aaatgaaaaa gatcttacta ggcgttactg gaagtatttc tgcttacaaa
     9541 agcgctgatc ttacaagtca attcgtcaaa ttaggtgccc aggtagatgt gattatgtct
     9601 aaaagcagca cacattttat cacgccatta accttgcaat ctctgtcgaa gcgcgcagtc
     9661 catacagacg tcatgcaaga atcaaatccg caggtaatca atcatatcga actagcaaaa
     9721 caagctgact tgtttctcat cgcgcctgct acagcaaaca ttatcggcaa gctagcaaac
     9781 ggcattgcag acgatcttct ttcaacagtc gcaatggcgc ttccagtggg aacaccaaaa
     9841 ttgattgccc ctgccatgaa cacgaatatg tatcaaaacc cgatcactca gcgtaatctg
     9901 gaaacattga gatctgtcgg ctatcaggaa attgaaccaa gagaatctct tttagcttgt
     9961 ggagattttg gaaaaggtgc cttagctgat attcagacga tcatcgaaca ggtcatgctg
    10021 actcttaatg aaagaaatgc ttagaaaaaa ggagtactta tgaaaaatac aaaaaacttt
    10081 acattaactg cgatgttttt agctattttg attttattag ctgttacgcc tttaggtttt
    10141 atccctatcg gtccaatcaa tgcaacaacc atgcatattc ctgtaatcat tgcttcgatc
    10201 gttttaggac caagactagg tgcttttctt ggcggtacat ttggactgat cagcatgatc
    10261 cgtagcacag ttatccaaac acctttgtct tttgtctttt ctccgtttat cccagtcatc
    10321 ggaacagaac atggaagctg gaaagccttg ctgatcgcgt ttattcctcg catcttgatt
    10381 ggggtggttc cttatttcgt ttataaaggt ctgcgcaaac taatgaaaca aaaagcagat
    10441 tccgtttctt tattcttagc tggactttcc ggttcattga ccaatacgat tttagtgatg
    10501 aatatgatct actttttatt ccagcaagat tatgccaaag tcatcggaac aaatttaaat
    10561 gctgtttatt cagctattct agcggttatt tttacaagtg gtatacctga aggaatcgtc
    10621 gcaggtcttg cgactgcagc agtatgcaat gtcttgttaa gatacttcaa gcacccttct
    10681 cttactaact gatagtcatc gtagccgatc tctgattttt ttctcttttg gtgttactat
    10741 tgaatggaaa gatttgacgt cgaaaggatg atccaaatga aaatttttgt tgtaggtgca
    10801 aacggacaaa ttggccgaca cctgataaaa gatttagctc caagttccca tgaaattttt
    10861 gcaggggtga gagatgttgc ttcccaaaca ttagtaaaaa aagagaatgt ttcgtatgtc
    10921 tcttttgatt taacttggtc cgtggaaaaa atgaccgaag cattcaaagg catcgatgta
    10981 ttgatttttg ctgccggctc tcaaggaaag aatcttctgc aagtagactt ggatggcgca
    11041 atcaaaacag tgatcgcagc tgaaaatgcg catgtctctc gctatctgat ggtcagtgct
    11101 gtttatgcag atgaaccagc aaaatggcct gagtccatga cagattatta tattactaaa
    11161 cattatgcag atgaatggct gaaacgaact aacttagatt ttgtcattct tcaaccagtc
    11221 acattgacta acgatgaaga agttacttcc attcaattaa ctaagcctaa tgagaaggca
    11281 tcaaaaacga tcactcgctc tacagttgct gctgtacttg ccgctctagt ggaagaaacg
    11341 gatatttctc gtacgactct agtactttct gaaggtagca aagagttgaa tacagcattc
    11401 caagaatggg caaaggagga atagatccat gcgtgccatt tcaatcaagc atcctggttc
    11461 tgtagatgta ttagaacaaa ttgaagtgcc tgttcctaaa ccaaaacaag gcgaattact
    11521 gatcaaagtc catacagcag ctgtcaatcg aacagatatt atgaaaagag aatcagtctc
    11581 tttgaaacct ccctacccta ttttgggagt cgaagtagct ggagaggtag ttgagaataa
    11641 aagtgatatc tccactttta ctcctgggac aaaagtatac ggattagtca atctaggtgg
    11701 ttatgccgaa tatgctgtga tgcctgccga tcgtgcaatc cttctccctg atacgctaga
    11761 ctatgtttct gctgctggaa tctcagaagt ttttttgact gcttatcaaa cactttactg
    11821 gcttggaaaa ttacaagaag gcgaaactgt cttgatccat gcaggagcaa gtggtgtggg
    11881 aacagcagcg atccaattag ctagacagct ttctcacgcg aaaatcatcg ttactgcagg
    11941 atcagaagaa aaactcgcct tttgtaaaga acttggtgca gatgaattga tcaactataa
    12001 aaaacaagac tttcaagaag aggtacgaaa aatcactgaa ggtcggggag tcgatgttat
    12061 tttggatttc atcggcgctt cttactggga aaagaattta gcttctatag ccgttgatgg
    12121 acgttgggtc ttgattggta tgctaggtgg gaccatcgtg cctgagatag accttggtgt
    12181 attgattggg aaacgtgtcc aactgcttgg tacattattg acacctagaa gtgatcagta
    12241 taaagcagag ctcgcacaaa cttttatgca aaaagctggg ccttttctag aaaatggcaa
    12301 gattcggcca atcattgacc gtacattcca attcagcgca gtcaaacaag cgcatgaata
    12361 tatgaaagca aacaaaaaca tcggaaaaat cattttgaag ataactgaat aaaatcatgc
    12421 tgatcaaaaa agaggctggg acagaagcgt ttaactccaa gaaataagaa gaaattcacg
    12481 aaaattgctt ttcaaatttt tgtgaatttc agcttatttc cgaaggaatt tcttctgctt
    12541 ccgccgttta tacgtgttta gagcgtgaga caaaagtgtt ctttactttt gtcccacgct
    12601 ctttttccga ataaacggtg ttcaaaagct tgcatctgcg gtaataagtc caaccaagtt
    12661 aaaaacataa gaagctgttt ttacttggct gttcttatta cttgatgcag ggcagctttt
    12721 tcacaacctc ttcactaaac agtgttcaat cagctgaccc tcggtattag ctcaaaacgc
    12781 tgatttcaca acctcttttt atttacgttc tatttcattc attttccgaa gcaaatcgag
    12841 ctgcttgtat gcccgcttgt cgcccaaaaa taatgatctc cgcaactgaa tttccaccga
    12901 tccggttgtt tccatgtaag ccacctgtga cttcaccagc agcatataac cccctaattg
    12961 gctggttttc tttatctaat acttcagtgt tcgtattgat tttcacaccg cccatcgtgt
    13021 aatggattcc tggtgcgatt ttgatcgcat aataattcgg agacgataag tcatgttcca
    13081 tggctgtggc acggttgaat tgagcatctt ttttctccgc aacatccgta ttccatccat
    13141 caactgtttt tgctagtgtt tcttttggta aatcgatttt ttctgctaat tcttccattg
    13201 tctttccagt tgtgacatat cctttttggt cataaaattc aatagctgtg gcacgatcac
    13261 gcacgccttg gtcaaaaatc aaataagctg atttttcagg caatgctgta attgctgcag
    13321 atactttatc ccttgtatcc atttcattga caaatctttt cccctcttga tcgaccaaga
    13381 ttgctccttc tccgcgaaca acctcaccaa tcaagacccc ctcatcctgc tgcacagttg
    13441 gatgaatttg tattttatcc atatcaacgg tttgtccacc taatttttca atcatggtga
    13501 taccatctcc agttgatcct tcttgatttg tcgtaatata atcagctaaa tcgggacgat
    13561 atttttcaat aaattctttg ctggcaccaa aaccgcctgt ggtaactacg attgcttttc
    13621 cggtgacctc ttttggttct tctccttgaa catgtacagt cacttcattg accgtttccc
    13681 catttttctt aatgtctgtc acatctgcgt tgacaaaaat agggatttcc cgctcatgga
    13741 cgttattcaa taacccctcc actaagtatc caccaatagc cgagccatca gacggacgat
    13801 gtgtcctctt ttcactcatc cctccagtga tcgttaagtt gtccagtttg ataccgtttt
    13861 gatctagcca atcgaccgca tcagcagagt gatcgacaaa gtatcgaagc atttctttat
    13921 cattcgttcc tccaccacct tttagcgttt cttcatagaa ggcatcattc gagtctttga
    13981 ttccttcttc tttttgaaat tttgtttctg aagcattcat accgcttgat gatttagatg
    14041 tgtttcctcc ggcaacaggc atcttttcca aaattactgg attcaaccca gcatcttttg
    14101 cttcgatagc tgctgccatc cctgcaccac cagctccaat aatcacgaca tcataagatt
    14161 ctttcatttc ttttggatct gtatatactt gttcagaagc gcctgatgat acttcggcag
    14221 attccttcgt actagaactt gtctgcgctg tatttttctg atctgcgccg catgcgctca
    14281 tagcaagaag tgcaacggct gttaataaac cagcaactaa ttttttcatt tgtatccccc
    14341 ttttctcctt atactatatt aagtgatttt tttcacaata tcaactctgt ttttctttaa
    14401 gtcatatagc tttggtaaac acacgcttct tagtataatt aaggatatac atgaaggagt
    14461 tattttatga atcatttgaa aacctttttt acgaacagta caaaaactgc aggtagaatc
    14521 acaaacggaa tctatatttt attacgtatc atcgtcgtta ttatgctagt ggatcaggtc
    14581 tggaaccaac actggggaaa tacaatgctt ttattactga cattaatttt atttgaaatc
    14641 ccttattttc tggaaaagat attaaagata cagattccaa atatgctaga aatcattttg
    14701 ttatctttta tttttagttc aacagtttta ggagagttaa gtgattttta tggctatttt
    14761 tcaatgtggg atacttttct acatgcattc agcggatttt tagctggggg tgtcggcttt
    14821 tcccttgttt atttgctcaa taaaaataca aaaaccatga acttgactcc tttattacta
    14881 gcagttgttt ccttctgttt ttcgatgaca gttggtgtta tgtgggagtt tgtggaattt
    14941 tcagcagata aattactgca attcgatatg caaaaagata cgatcatcca gcaaatcaat
    15001 agtgtggagt taagtaaaga cggaaacact gtctatcatg ttccagatat cactcggaca
    15061 atcattgaaa gtcaaaatgc agatggtaaa acagataaaa caatcatcca aaatggttac
    15121 ttagacgtgg gaatcatgga tactatgaag gatttatttg ttaattttat tggagcagtt
    15181 gttttcagtg tatttggtta cctctatagt cgaaacgatt accaaaaatt tacgttcatc
    15241 aagaatttta ttcctaaaaa aatcaaacga taaaacatgc taaaaaacaa gagaaggggc
    15301 agtgacaata cttttgtcac tgccccttct tttttgaatg tatggcatgc cattagttat
    15361 ccgatagtat taactcaaaa aagtaagata tgaggaatga ctatttcgtt ttttatccca
    15421 atactgagga cttatttcac catttcgtta tttatctaat ttacttaaaa cctgcataac
    15481 tttttcataa tctggattag gtgtgccgtc tagattttca gcaataaaag taaaacccat
    15541 ttttttataa agagcaatcg cctgatggct ccatgtctgt gtgtgaagat agattggtcc
    15601 gtccgtatgg agggtaggaa attcttgcaa gactctggca gtcaatgctt ttgcgagccc
    15661 ttttccttgg taatctggtt tcactgctaa ccaatgaaaa accggataca cttgctctct
    15721 tgattttttt cgccaagcgg tacaggttgc tactttttct cctttttttg tctctacaaa
    15781 aaacatcctt ctttcaagtt cttcaggata aggagcaaag ttttgttgaa aatactcaag
    15841 tgcttcatct gtcgtttgaa attccccaac ggaagtctca atctccgccc aagcagattc
    15901 atcttctttt tgataaaatc gaaattcaaa accttccgct aaaggcgtga ttggaacatt
    15961 ttgttgaagt ggtcttgtca tccagatttc tgcgtaaggt aacgttttat ctaacatttt
    16021 tctatccctc ctcgtctcca ttatgccaaa taacatatga ctcagctact tatttgacta
    16081 taacagatag agatataaat cagaaccagt catctgcgtc aaattcattt cgattagcgt
    16141 atacccatgt tcctgccata cctcgcatga aatctcctaa agcagaagaa ggaatacctc
    16201 caccaggtgc gggtgttccc ggactaggaa gtggtacttg cggctgcaga tgctcatcgg
    16261 tggaatcaat agttgacaag cgttttttct tcgtttcctt ctggtcatct gattccttct
    16321 gatcttccga ctgtttagca acaaattctt tttctgattg ttgttttatt ttaggctcta
    16381 aaatttcatt ttccaatcca gaaacttgtg gggccaaatg agcttcttgc cttatcgttt
    16441 tattagattc tgagattttt ctagatattc ttgctaactc taggcttctt gtttgtttta
    16501 ctttccctgt tggagaaact gcatgagcca tttgttgttt tttttctgac aagctttctt
    16561 cttgtctttt ttgttctttt tgatctatct gtttgtttaa tggtaaaaca tgtaatagtg
    16621 actgagcatg gagttcttgg agtgaatacg ggtcatgata actatacata atcgtaaaat
    16681 cacctgtttg tttggtcaaa taaccatcct ccaatggtac ttcattgatt gtaaccgata
    16741 catcctttaa cggtacgggt ttacctaagg aatttgttgc tgattggatc aactcttctt
    16801 tgtttatttt ttcgtttgga tgaacaataa gatcatgacc ttctaatgaa cgattgtctg
    16861 gtatataaac ataagtaaag gtaatttccc ctcctgattg cttcctatta ttcatcagtt
    16921 ctgagtgaag tacttcaagg atctccgacc agtgactttt tctgtctaat ccgtttgctt
    16981 gcatccaatc agaaatagaa gtgactttcc cattttgttc ataagtcgat aaatctatat
    17041 ttggcactcg atcagaaaat tcagcaggta ggcgcaaatc aggaatacga tttacactac
    17101 tcatatgtgt ttctgcttga agttctttat ttgtttgact atctataaaa tgagtgatga
    17161 cagtcgatga agcagcagat gcttctacat aaactacagc tgttgtttct gccacatttg
    17221 atgttttcga gtctatataa gttaatacaa cgggatattc tcccggagtt gtagtatcta
    17281 ctgtcccgtt cattttgatt tcttctttat ttcctgaagt tccatcgctt tttgttacat
    17341 attcaacaag atctttaggg gcgtaactct ctcctgttct taagtgaaga tcttttcctt
    17401 tgatagctgt ttgatcagca cgaacatgga tcacagcaga tgcagtcatt gtttttaaag
    17461 caattggatc aaaataggac aaggaaatag tagatgttcc tgtattagtc gtatccacga
    17521 tattcccatt gtttgaaatt actttggaca tatctccttg tgttccatct gcgttcttca
    17581 gcctttctac cagatcagat atcgaaactt ttgtccctgc cagaacatcg attttctttc
    17641 tttcaaactg tgaataatct ttttcatata cataagaaac ttgtgcgctt ccaccgtcct
    17701 ttatatctgt caaagcatga ttcaaaatat cagtgatctg ttttaactga tcaccttttg
    17761 taggatcagt catatcggaa aagatagaaa gcggcacact gcttccggtt tccgatgtcc
    17821 ataatgtttt gttaggaatt aaccagtagt ggtttatcgt tggaggataa ctgactttat
    17881 tataggaagt caatgcagga agtagctgtt ttccatttgc atcagtgaaa gtatgagtaa
    17941 tagtgatagg ggaatcagtg gtctcagaaa cagaggtacg tacgaccttg atggtttgtg
    18001 tcgttgcctg aacgggtaca tgcatataga cacctacaga taaactgatc agcatcgtgc
    18061 gcatcataaa cttaacgtag tgtttttcag aacacgaccg ttccttatct aaacgacaag
    18121 cgtgtttatt tagttgtttt gaacgtcttt ttgaacacat ttattcttag tcctccctac
    18181 tcttgtctaa acatgaagta gtaattttca taagatgatt tcattatata aataaaatca
    18241 aaagaagatg gactattagg agagtatttt ttttgatttt ttattgtttc aagaaaatcg
    18301 gaataataac ttatgtactt tttaattttg ttaagtaata tatctagtta tatctagtta
    18361 tatctagtta ccttttcttt gaaaaaaaca taaatcagct aataaatatg tgagacaaag
    18421 ctgccatcca taaatactag ctgatttttt cagttaaatg tctatttttt tctctgatga
    18481 tggtatttcc aaaatattcc cagtcatctg gagtcggtgg atttttccaa attatctgtt
    18541 ctttattaaa tttttcaagt aaacaatcag ataaataaat attcgtacga gaagtgattc
    18601 gactctcaat cacaatattg taatttttaa atcctttcac ttgagaaata atgtaatcgg
    18661 tataagcaga tccttgcgaa aaatcaatac agacatgaat cggtgcttca aaatatgata
    18721 ccggacaaat accgaccaat aaaaagagat aatcataaaa taagcgaatc atgaaacgtt
    18781 catcttttcc caagaaatag cgtttattct cttgtatgac cttttggatt gctgtactga
    18841 atattggata cgtctcgaag aaaaactgta gctgcttttt agacgtaaag ctagtcatct
    18901 caaagtcgaa tatccaattt tttcgattga catgcatcat acccatacga agttcttttc
    18961 gtatatatag tctttcttct tcagagattt caatcgaaaa tggtaattga tcaatcaatt
    19021 ccactgacat tttttgacta atcatgtgga tatcatgaaa atgagcttcc gcaagtccaa
    19081 atgcgccatc taattcaaat tcttcttccg tgatcaaaaa caacatgata taagaaatct
    19141 catcaatgat ctgctcttta gggatatgaa gaaaagaaat atgtgataaa tccttgatga
    19201 tcttcattcc ttctgagctc ttaaagtatt catctgaaaa gaaacgtttt ccgattggtt
    19261 gattcccata ggccctcaac aaactaatag tggttagcaa attgaatttg attcgttttg
    19321 ttgcagacag ttttaaattg aacagatatt caaaatattg cacgatactc tttgcttcat
    19381 tcatgacgct ttctctaaat ggcatagaaa aaccattaaa gaccccgaaa tataccccaa
    19441 ataatacgtt ccgtatgttt atttcttccc caactaatat gtttttcttt aactttattt
    19501 gatgctgttc aagaaaagag actaattctc ttctttttac ataggctctt gatatgctta
    19561 aaaaatgatt ctctgcaaat ttttcgatcg ttacttttga atccacgatc tccgttaaca
    19621 gtcgagcaat ttttgatcgt tgaaagtaga ttcttcttaa atttttgata tccgtcaaat
    19681 tcagacgttc gacatggatc tctgcttctt ctgaaatttg gatctctggc tttgttttga
    19741 attcagtaaa ttctttattt aattctatga tataatttct tgttttaaat ttagacaaac
    19801 ctaatgtttc atataactta ggcagcacta cataattctt tttctcaaat tctaaatatc
    19861 tagctagcag cagtttttct ctatcttcct cttctataag gtaatccaac ttcatatcct
    19921 acacctcaaa aaatgcctca taccaattac ttgatatgca gatgaaagtt catcttttca
    19981 cctatactga ttttatgatg gattatgctt gttttttcat cagttattct cattttttat
    20041 cttttttttg agaatattgc aaaaaatgga aaaatttatg aggaaatatt ctatattttt
    20101 tgttttattg tgttaaaatg tacaagattt gcgccatttg cgtaaacaac cacaaaaaag
    20161 agcaggacgg ccaccgtcct gctcttttac ttattttaag ttccattact tattaattgg
    20221 ctaaacttct gcttgtttct gatattgctt gtttttctcc aatgatccgc acttctgttt
    20281 ctaaagacac atcaaatttt tctttgatta cttcttggat gtgcgcaatc aattcaatat
    20341 aatctgtcgc tgtcgcatga tcgatattga cgatgaatcc agcatgtttt tcagagactt
    20401 gtgcaccgcc ccatttcagg ccttgcaatc ctgcttgttg gatcagctga cctgtatagt
    20461 gtcctactgg gcgcttaaag acacttccgc atgaagggta ttctaatggc tgttttgatt
    20521 gacgcaattc ggtcaactca tccattcttg ctttgattgc ttcataatcc cctgtttgca
    20581 aactgaatcg agcttccaat acgatagcac gtaattcttg gactttactg tgacgataag
    20641 aaaataccat ttcgtctttt gtcaaagttt tcaatgttcc atcttcaagc aaaagatcca
    20701 cttcagcaaa aacatctttg atctctccgc catacgcacc tgcattcata taaaccgctc
    20761 caccgacact tcccgggatg ccgcaagcaa attcaaatcc agtcaatgat tctgccaaag
    20821 ctgcataagt cgtatcaatc agtgaggcac ctgcttccgc aatgaccatc gttcctttga
    20881 catgaatctg tttcatttca gtcagcatga tgactacacc gcgaatcccg ccatcttgaa
    20941 cgatcagatt gcttgcattt cctaatacca tccaaggtat atcatggatt cggcaataat
    21001 cgatgatttg ctttacttct tcttgttttt tcgggaatgc aaggacatca gctggtccac
    21061 ctgttttcgt aaacgtatag ttcatcaatg gttcatcaaa caatatagta atcgtggcta
    21121 agctttcaac tatttcttct ttattcactg aggattttcc tttcttttct caaacgtcct
    21181 cattattcta tcacgcttaa tacaatcttg ccagtcttgt tcaaagttga tgacggtagt
    21241 gatctttaag cacttcctca cataattcat gacttcttac aacttctttt tgtttaagca
    21301 attctgtttc cgatttacct aaacggatct gagaaaagaa ggcctctacc attggctcaa
    21361 acccgcgttt gactagcgtg tttgtccagt cgccaaattc tttcactttt tttccatcag
    21421 catcttgaat gacaagctgg gtcagatcgt ttacttcata agtaccattt ttacttgtta
    21481 cttgatattt ttctatatta gcgccacttg ctaaatccat cgttaaaata gccgtttgat
    21541 tttgtgtttc taattgtaaa atgcatattc caaaaattcc tttgtttctc ttatctggta
    21601 ttttgttctc aaaatgggtt catctaataa atacacagct gtatcaataa gatgtaaaaa
    21661 caaatcataa aggacgaact ctgtcgtttc ttttgccgct attcgatttt tttgcaggtg
    21721 gatcaaccgc ttatctggga tacgtttcaa ttcttctacc ataggagcaa agcgccggtt
    21781 gaaaccgatc atcaaaatta tttggttctt atcagctaat tcttgcaatt cacgaacttc
    21841 atttagatgg acactcagtg gtttgtcaat ataaacatgg ataccatttt ctagacattt
    21901 tttggctaat tcataatgta cttttgttgc tgcgtggatc atacatgctt cgattttttc
    21961 ttctaaaagc tcatcgatcg tttcatatag atgttggaac ccgtactctt tttgaattct
    22021 ttcttttgtt tctttatttc ttgttgcaaa ataaaaatca agtgttcctt gttttttcgc
    22081 ataagttggt aaatatgctt tttctgcgat attccctaca ccgattacac caatcttcat
    22141 ctactttcct cctggatcat ttagttactt tcatcttaca ccatttttta ctaaaatgag
    22201 gtacaatagt atcgcaaagg taaggaaatt aattcgaagg agtgtgcttt tattgaaatt
    22261 tatctcttgg aacgtaaacg ggcttcgtgc catcgtaaat aaaaattttt tagaagtttt
    22321 tcatgagtta gacgccgatt ttttctgtct gcaggaaacg aaactccaag caggacaaat
    22381 tgatttagat cttccaggtt attatcaata ttggaattac gcggaacgaa aaggctattc
    22441 cggcacagcg atttttgcta aaaaaccagc attgaatgcc acttacggaa tgggtatcga
    22501 tatccatgat acagaaggcc gtctgattac tttggaatat tccgatttct ttcttgtaac
    22561 ctgttacacg ccaaattctc aaagcgaatt aaaacgttta gattaccgat tagaatggga
    22621 agaagccttt tataattatt tggaaaatct aaaaaaacaa aaaccagtca tcgtgtgtgg
    22681 ggatctaaat gtcgctcatc aaaagattga tttgaaaaac tggaaaacga atcaaaaaaa
    22741 tgctggattc actccagaag aaagagcggc tctttctcga ctgttggata acgggtttat
    22801 cgatacattc cgttattttt atccaaccca ggaaggtgtc tactcttggt ggaactaccg
    22861 attcaattca aggaaaaaca atgctggttg gcggatcgat tactttttga cgagcaaaga
    22921 tttagagcca ggactagctg atgcaaagat ccatacggac attatgggca gtgatcattg
    22981 tccagtagaa ttagatttga aataaagagg ttgtgaaaaa gtcgtttagt ttcgagtatt
    23041 aagaaaaatt ttgtgaaaat ggctttccac attttgcata aatttggcat aataccgaga
    23101 aactggcttt tgaacactgt ttatcgagag attgtgaaaa agctgtcctg catcaagtaa
    23161 taagaacagc caaacaaaaa tagttcctca tatttttcgt ttggttgggc ttattaccgc
    23221 agatacaagc ttttgaacac cgtttattaa gaggttgtga aaaagctgca ctgcatcaag
    23281 taataagaac agccaaacaa aaatagttcc tcatattttt cgtttggttg gacttattac
    23341 cgcagatgca agcttttgaa caccgtttat taagaggttg tgaaaaagct gcactgcatc
    23401 aagtaataag aacagccaaa caaaaatagt tcctcatatt tttcgtttgg ttggacttat
    23461 taccgcagat gcaagctttt gaacaccgtt tattgagaag ttgtgaaatc agcgtcctga
    23521 cctgagtatt agagaaacaa atggcaaaat agttcctcat attttgctat tttttgagct
    23581 aatacggagg gtcagctgat tgaacactgt ttagtggaga ggttgtgaaa tcagcgtcct
    23641 gacctgagta ttagagaaac aaatggcaaa atagttcctc atattttgct attttttgag
    23701 ctaataccga gggtcagctg attgaacacc gtttagtgga gaagttgtga aaaagtcgcc
    23761 tactttcgag tcgtaagaaa tttttttgaa aatggttcct cacaactttg cataaatttg
    23821 acttaatacc gagaagtcat gatccccatc taactccaaa tcacaaggaa tgagttcaaa
    23881 aactagcttt tctcaacaaa tattacataa aaaattctat gttttttgtt aaatttattt
    23941 gcttttttca aaagtatgtt acagtaattt cccaaggagg ttttacagaa atgaattttg
    24001 ttgccatgga ttttgaaact gccaatcatc agccttatag tgcttgttct cttgcgctag
    24061 tcatggtaaa aaatagccag atcgttgatg aattctatac attgatacag cctgagactc
    24121 cttttttctg gcgaaatgtc caaattcacg gaatccatca agaagacgta cgcaatgcgc
    24181 cgaaattccc agaagtctgg caaactatcc aaccatattt tcaaaaaaat cgtttagtcg
    24241 ttgcacataa tgctgctttt gatacaaagg tcttagcggg atgcttagat tattatcatc
    24301 ttgaacagcc taattatctt tctttatgta cagtgaaaag tagccgtcgc ctgtttcctg
    24361 aatttccaaa tcatcgattg aacactgtgt gcgaaaattt gaacatccaa ttagatcatc
    24421 accatgatgc attggaagat agtcgtgcat gtgcggaaat cctgctttat caagaaaaaa
    24481 aattcgggac agatccattg aaaaaacttg tgactataaa gtaaaagaat acttatgaaa
    24541 cacacaaaga ggtcgtgagc ctgccgtttc actccgagtc acaaggagca atttcaaaaa
    24601 atagcttctc atgtttatta aatattgtga ctggtgaccg aggagctggc aggagaacac
    24661 cgtttattgg agaggttgtg aaaaagctgt tctgcatcaa gtaataagaa cagccaaaca
    24721 aaaatagctt ctcatatttt tcatttggtt ggacttatta ccgcagatgc aagcttttgg
    24781 acaccgttta ccaagaggtt gtgaaatcag cgttttgacc tgagtattag agaaacaaac
    24841 ggcaaaatag ttcctcatat tttgccgttt tttgagctaa taccgaaggt cagctgattg
    24901 aacaccgttt attcaaaaaa aatggactgc gacacgactt ttgtcacagt cccttcgtgt
    24961 gtttttctgc cttctcaaaa ggatgacagt ttctcactct tttcctattt cttctattca
    25021 atcaaataac tcattttata tacatctaaa aattcaccta gatctgttct tgcccctcta
    25081 ggcatgaccg cttcgatttg gaagcccatt tttcggtaaa ggtgtacggc tctttcatta
    25141 cgaacttgaa cgtcaagctc caatcgaaaa agtacaccca tttccttcgc ccaactgatg
    25201 atttcttcta gcataagagt gcctagtccc attccccaat attcctgcag aatactgata
    25261 ccgacttctc ccacgtgaga caaacgaaat tgactgtctg ccttgacaga tgctgttcca
    25321 ataatcgtcc cttcatagat tgcaagcagc aataaattat tattgctttc gtatatataa
    25381 tccaactctt cttctaaggt ttctggtggt aacaggagtt ctgcttcatc caaaactaaa
    25441 aattctgtct ccttattaac ttgtcccatc atcaaaagaa tgtcttttgc atctcctggc
    25501 actgcttccc gcaagatgat cccaacttct tcactcatga ttttcagccc atttttctag
    25561 aattcgctgt ttgaaggttt cactttgctc cccgtatgag attagtttca cataccgctt
    25621 ttctaaatct gtatcacttt tttctaaaat cagttccaaa taatcctccg gcagtgcttc
    25681 ttctaataga tttccccatt caacaacgga aagcccatca ccttcaaaat attcatctaa
    25741 ccctaaatct gctccgctag ctgctacccg ataaatatcc atatgataca acggaatccg
    25801 accttgacta tattctctaa taatcgtgta tgtcggactt ttgatcattt gcgttatccc
    25861 taatccttgg gcaattcctt tcgtcaacgt tgttttaccc gcacctagat caccagtcaa
    25921 tatcagattg tcacctggca ttgcggaatg accaattgcc tctgcgaatt gttctgtcat
    25981 tgttaatcct gatagttcga tcatttttca tcttctcccg ctcttctttc tttttgccag
    26041 tatatcgcgt aatgaagttt ttttaaagaa aaaatgaact agtcaagaac agcagctgct
    26101 gtttttggct agttcgcgtg tatttgttaa tcaatcaatg tttgtgctgc tgtgataatc
    26161 gataatttat atacatcttc ttcatttgct ccacgagaca aatcagaaac cggtttgttc
    26221 aagccttgta gaattggtcc gattgcttca aagttaccga aacgctgagc aattttatag
    26281 ccgatatttc ctgactgcaa ttctggaaat acaaagactg ttgcttgacc agctacttct
    26341 gaatctggcg ctttcagttg tgcaactgaa ggaacataag aagcatcaaa ttgcaattcg
    26401 ccgtcgatca tgtattgtgg cgctagtttt ttagcgattt tagttgcttc aactactttg
    26461 tctacttctg gcgatttcgc tgagcctttt gtcgagaagc tcatcattgc tacttttggt
    26521 tcgatatcga acaattctgc tgtttttgca gaatctacgg cgatttcagc caattcttgc
    26581 gcagttggat tcacgttgat cgcacaatcc gaaaagacat atttttcttg atctcttcca
    26641 cgtaccatga tcatcgctcc gcttgtccga ctgatgccag gctttgtttt gatgatctga
    26701 agtgctgggc gaacagtgtc gccagtcgaa tggatcgctc cagagaccat tccgtctgca
    26761 atccccatat acgtaagcat cgtaccaaag taattcacat cttttaaaat cttttctgct
    26821 tgttctttgg atgcctttcc atttctacgt tcaacaaaag tatccaccat ttcatcccac
    26881 ttatcgtaat tatcagggct gatgatcgta aagctagatg ttttgattcc tctggcatgc
    26941 gctgcatttc ttatttcttc ttcgttccct actaaaatgg gttccacaag ttcttctgct
    27001 ttcaaccggg cagctgcgcc taaaatacga gcatcagtag cttccgggaa aacgattttg
    27061 atcccacggc gaacaatttt aaatcttaaa ctatcaaaca attccacaag atgacctcca
    27121 gacgttttta tatgtattat catacactat tccagaaaaa aagaacagtt tattttatct
    27181 gtatcagtca aaaatgctgg aaaaattaag tttttcacat acaaagcgaa ctgcactata
    27241 acaggaaagc gctgttttat tacactgttt caggcagttg ccaatcaatc ggttcttctc
    27301 ctaacgcaag gagcgcatca ttcgttttcg agaagggttt ggaaccaaaa aagccacgac
    27361 ttgcagataa cggactggga tgtggagatg ttatgatgat atggcgactc ttatcgatca
    27421 ttttgatttt ttcttgtgcc ggttttcccc acaagataaa cacgattggt ttttcccgtt
    27481 catttaattt ttcaatgatc gtgtctgtta atctttccca acctttcccg cgatgagaat
    27541 acgcttgccc ttcccgaacg gtaagaacgg tgttgagtaa aaggactccc tgtttagccc
    27601 atgacactag atttccatgt tgaacaggtg cgattccaag atcatcataa agctctttat
    27661 agatatttct taacgatggc gggatcttta cgccaggttg cacagaaaaa gataagccat
    27721 gagcttgatt ttctccatga taaggatctt gtcctaaaat caccacttta acttcttcat
    27781 aaggagtcaa ttccaatgct tcatagatat gatacatatc tggatggatc ttttgggacg
    27841 catattcttt ttttaaaaat tctcttagat gcagataata atcttttgaa aattctgagg
    27901 acaaaacttc ttgccaactg ttatgaatga tttctttcaa aaactccacc tcctaataaa
    27961 aagaataact cacattttct tcaatcacaa gggacaatct tcaccctcag cacttgatta
    28021 atatggtaaa ctaggaacaa gaagcagaaa ggaacgataa tcattatgat caaattaatt
    28081 gcatcagata tggacggcac attattagat gcccatatga gtgtttctcc tgaaaatgcc
    28141 gaggcgatac gttttgcaaa tgatgccggt gttgagttca tggtcgctac tggtcgaaac
    28201 tatcaagaag ctcgcgcagc tttagatgag gtaggaatcg attgtgcgat gatcactttg
    28261 aacggggcac aggtatttga taaagaagga aattcattgt ttaccgtgtc gattccaaat
    28321 aatcaagcaa tctctgtttt agatattcta gatgctaacg gtatttacta tgaagtagca
    28381 accaacgatg gtctttattc tgaaaatcaa gcgaaacgaa ttgaaagttt tgcttccatg
    28441 gtggctaccc atttacctca ccttacgtat aaaatggcga ttgccatggc ctcagctaag
    28501 ctggagttat tgcacatcac atacgtggac agtattcgtg ctattttgga agaaaagaat
    28561 ctggaagttt taaaaattat ttgttttcat acagaagggc cagctgtatt aggtccagtt
    28621 ggaaagcaga tttctctttt aggcgatcta gccgttactt cctctggtca aaacaatatc
    28681 gaagtgaacc ataaaaacgc tcaaaaagga attgctgttg cccatgtcgc tcacgagcgt
    28741 gggatttctt tagaagaagt catgacgatt ggcgataact tcaatgatgt cagcatgctg
    28801 caagtagcag gagtcagttt cgcaatggga aatgcagaaa tcgaagtaaa agattatgcc
    28861 aaatatacaa cggacacaaa ccttgaatct ggcgtaggaa aagccatatt gcgcgcgatt
    28921 gcagaagact tgtagtttta tctagaaaag agggatatag atgtcagaat ttttcattca
    28981 ggaaaagcag cttggacgtg caactcggac aattgtcaaa aacgaaaaag gacattccct
    29041 gtttttgatg gttggtcgct ggggaacaaa gggcgatgca ttgtctcttt atgccatgaa
    29101 tggcgatctc gttgctcaca tcaagcagat aagcctgaca ttcggtacgc gttttgagct
    29161 gtataaagag ttcgaaaagg tgggaaccat gcagaaaata ttcaattggc ccggtgactt
    29221 ttattatatt cgtagacttc actggacagt ccaaggtgat atctataatc atcaatatca
    29281 aatccatcat ttcaatcagc aaatcatgaa aatggataaa gcaacacttt tttcaggaga
    29341 ttactatgta ttggatgtct caaatgatga agatgctcca gtttgtattt gtattgctgc
    29401 ggttttagat tactggctct accgtaaaga caaaagtcgc gataagcctg tttcttaccg
    29461 acttaactta agttaaaaag atgtacctga aatgcggaaa tacgcatttc aggtacatct
    29521 ttttagatat tcttttgcat atgatcataa agatgaccac tgatcatccg ctgaccgaca
    29581 actttgaagt catggcgttc gtataatttt ttagcctttg gatttttttc atccacactt
    29641 agaccgatga cggagcgatt agctttcttc gccaatttag gtaatgcttc taataatcgc
    29701 gaaccgatgc cttgtcctct aaaatcttct gatacactga tagagtccaa ataccattcg
    29761 ttgggaaacg tttctttatc aatgaacaaa cgtgtagacg catctagctg atatttctct
    29821 aagataggta ccagtggctg atcgatgatt gattcttctt catctgtata accgtaagca
    29881 actcctgcaa ctttaccgtc tatttcttct acgatacctc gtgaataact gtaacgataa
    29941 tttggatcag tgattgcttc ttctaaaatc tctaaagtct tttgttcccc tgtctgcttc
    30001 aaaaatggca gttccatatc ttttagaatc actaagatca atggggcgat ttctggagca
    30061 tcttcttttc tcgcaaaacg aatcatagtt tcctctcctt ttctccattc taacatgcag
    30121 aaaaagaaat cgcaaaatcg ttattttaaa aaatcttcaa tcttttcagt aatgaaataa
    30181 ccatgagtaa cgattcttgc cgcttcagtt cggcaataag ggcagacgac tggcatttct
    30241 ttatcattat gttcgactac attattgact tcttcgtatg caaatttttt tccgcaatta
    30301 gggcatttca ttttttccat gttatctcaa cttcctttca tctttactct cttagcttac
    30361 tcttatattg taaaaaagag aagcaatatc cttcttctat gcagatatcc atacctgacg
    30421 gtcctgttct ccatctatta atcggacttt ataataagga cgttcatctt tgactagaag
    30481 tgtccactct ttcacttttg cttttttccc gtagtagctg actgcttcct tcatcgctgc
    30541 ttgcggttgt ttgaactctt ccgttttttc tatatcaaaa agatgttctg cggccttttc
    30601 cgtgtcattt cgtacggttg ttttcccagt ggatggattg actgctatga cttgtccttc
    30661 acaaaaaaac tggtattcat atgttgcatt cgtaggattc tccaaatctt tttcaactgc
    30721 aaaatgaata gcagatatgt tatgttcttt tgtttcgttt tttacgattg ctgctgcttt
    30781 tttcaatgag atccgatatt cctggtcact aatatcatcc atgtgaaaag cggcattgag
    30841 cagtcccgtc ataccggtaa tccctattac gatgagggca gcaacaccaa acatcatttt
    30901 tttcattctt cattctcctg tttctttttt ttaaagaata tcaagaaatg aacgaatgaa
    30961 aaatcgaatg aaacgaaaaa aaagtgacaa ttttgttatc tttattcgtg cagttctaat
    31021 ggcaatccgt ctggatcaaa gaaaaacgtc attttttttc ctgtaaaggt atcttctcta
    31081 atcggttctg attcgatccc taaggactgc aattctgcaa ttgtttcttc aatatcgtct
    31141 actttgaaag caagatgacg caagccacaa gcttctggat agtttggtcg ttgtggcgca
    31201 ttagcaattc caaaaatctc caattcagca cttcctagtt tcagatctaa tttatagtca
    31261 tctcgttctt tgcggtaatt ttctctgatt acttcaaatc ctaatttatt aacataaaaa
    31321 tcacgtgatt tctgataatc tgaaacaatg atggctatat gatggatcgt tgtaaggttc
    31381 atatgagcac tcctattctt cgtttaagct cggatctata ttaatctcca gttccattgt
    31441 aaatgtgtca gattgaaaaa aatagctgtt tttccttttt ataagaaaaa aggcaaaaaa
    31501 aacagaaagt aggtcctcca agacactctt cctgttccca atataataaa tgaaagtaag
    31561 aaattatatt ttcaagaaaa caaacagaaa attatcataa cacaaattat ttataattga
    31621 aagactagtt ttttttcaag aaaagcatac aatagattgt gttagtaaat acagaacaca
    31681 ctacatttag tgtcttaagg agtcctcata catgaagtca tattttcagt ttttagctca
    31741 tcagctaaaa ggctggccgc aacaaaatta ttatcttttc tttttcagtc ttggctgcca
    31801 ggtcatgact cttgtcaata gtcccatcac ttggctgtcc gttattacat ttatcggtac
    31861 cacgcttggt gtattgtgta ttttatccat caatgcggca aaatcagtca acggtatttt
    31921 aggtattttg tctgcgattt gttttattat cgttgggttt tcagcaaaga actatttaag
    31981 tatcggtgaa cagattgctt atatgatcac attggatatc cccgtattgt taagtaaaga
    32041 atggaatcat aatatggctt caaaaatccg aaaattcact ggaaaaagct ggtttatcgc
    32101 aatcatcagt actttccttg tctatcttgt ttcaggattc ctgattggtc gttatacaga
    32161 tgatcctcgg ccgtgggtag atgccattgc tttttctatt agcttgactg ctggtatcat
    32221 cagtttcttg cgttacaaca accaatatta ctggtggtta gcttcagggc ttgctcaaat
    32281 ggtcctttgg tatatttcat ttacgcatgg atctgcaagt ttggcgatgt tcgtgaacag
    32341 ctctgtttac ttgctgaatg atgtccttgc atttaccgtt tcaccttggt ataaccaaaa
    32401 agaacgtgaa cgtatgcaaa aaatggaaga agaatactac aacgcacaac aacacgcata
    32461 aaaaaactga gcgtgggaca aaagtaaaga acacttttgt ctcacgctct aaacacgtat
    32521 aaacggcgga atcagaagca actccttcgg aaataagctg aaattcacaa aaatttgaaa
    32581 agcaattttc gtgaatttct tcttatttct tggagttaaa cgcttctgtc ccagcctcta
    32641 ttttttatag taattccttc agatactttc ttgcctcatc attgaaacgc agtgattctt
    32701 ctaacttctg ataatattcc aacgcttgtt tctgagcttc agtaaaacga taatgttttc
    32761 ctttccattt gtcgattgtc tcttgcacat ttccagattg gatatctttc actactagtt
    32821 gccatttttc ttttgagact gtacggtctt tcttatcagc agattgtata gcttctcgtt
    32881 ctttacgcaa tacttttaaa aaaccatttc tgactatccg aggaatgctg tcgaagaacc
    32941 cttctgtaaa accatagcga caatattgct tccaaataaa tagatagatt tttggttgga
    33001 tgaatcgttg gtttttcgca aaatattcca tctgagcagt gacttctggt gttcgttgac
    33061 gttttgtctt tctcaacacg gaaataaatg tttcaaaata agcattagga tgtactggca
    33121 cttcttcata tacgatggat tgccaatctt tacgtaaaaa tgcgcgatag ttgatcaaga
    33181 attcttctac atcctttact aattcttctg caaagtcgtc aaatagttct ttttttatct
    33241 gtcgcttttt tgactgccca ttgatgtgtt cacttatttt cttgatttca ttttccaatg
    33301 cttgataatc cgctatgtaa atcggcattt ctacttggcg aaattctgcg agccgctgag
    33361 ctaattttat atccggtaaa tatggctgtt tcatccgacg attttggtac aagacaaaac
    33421 agtatttttg ccatagtcct tcaggaaaat cgatattctt ctgcttaagc cataataatt
    33481 cgtctaaggc cagatcaact tttgtcattc cctgatggat cgaagctgcc actgtcggag
    33541 agacatgcag gtgatcggca aagtggttga tgcctagttt taggatcttt ccggtttttg
    33601 gcgatttaac gatgtattgc acttttaatt ctctaccaca ctcacaatac aatttttgct
    33661 ggcttcgttt tgttcgaaaa aacggattga tcttgaagtc agaaaacacc caatctgttg
    33721 cagctaaata atgttcttcc ataaaacgag agctgattag atatcggcgg tgcttatcga
    33781 ctagttcccg ctgttttttc gttaattttg catagatctc ccaacgttga ctgcttgtgt
    33841 attgtttaga aattttgatg ggatagcttt tgctgatttc ttttggaaac cattcttcaa
    33901 agacggattg ccattcttcc acggctgttt ctttcctttc taattacaaa aagctggcta
    33961 ctaacataac gttagcaacc agccagtgtt tcttgctaaa ttagtgagtt gttccggcat
    34021 ttccggaaat atcttcttta ttttctactg ctgcttcaac tgcataagtc aaagaagaag
    34081 caatgtcttc taaagacata gaaggcgtac ccactggacg atcgatcact tgatcgggtg
    34141 agaatggcac gtggatgaac ccacctcgaa ttgccgggaa ttgtgtttcg atcaaatgaa
    34201 gcaaacgata catgatatca ttgcagacaa atgttcctgc tgtataagag atgtacgctg
    34261 gtagaccatg atcttgtaca ttttttgtca ttgctttgat tggcaatgag gtaaagtaag
    34321 cggctggacc gttttcttct aaagccgtat cgaatggctg atttccttca ttatcaggga
    34381 ttcttgcttc tgctagattg attgcgacac gttcgaacga gactgctgac cgcccacctg
    34441 cttgtccgac acagatcacg acatctggtt ggtgctgttg gatggcttct ttgactactt
    34501 gactgctttt ttcgaatacg gtcggtactt ccactttgat gatttcagca ccgctgattt
    34561 catctggcat tttttttact gcttcatagg ctggattcac tttgtcccca ccaaatggat
    34621 caaaacctgt tactagtact ttcatctgtt gttcctccgt ccgattgatt taacatatgg
    34681 ttatctttta tcataccatt ttccttgaac agcgtaaata aaggaaacaa tagtttaaat
    34741 aacataacag atcaaactta atatattctt ataaaaaaat agtgttccac tacaatgtta
    34801 gaagaggttg cgacaattat tctgtcacaa cccctctctt ctattattta aatagaatca
    34861 tataagcaat ttggaaaact agcataaata acgcaataaa caactggttt ttgatcactc
    34921 cgtatttgtc tttcatctcc agcatcgcta caggcacgat attgaagtta gcagccatcg
    34981 gtgtcagcag ggtcccacaa aaaccgcaag tcaatgcaac cattcctatt aacgctggat
    35041 tcgctccatg actaaatacg aatggtgcac cgatcccaac cgtcatcacg gtgatggccg
    35101 caaatgcatt ccccatgatt accgtaaata tcaccatgcc aagagcgtaa atgatgatgc
    35161 cgatgttcac atttccttct ggaacgatcg tacctactgc attggaaatc actgtcccaa
    35221 ctccagcgct tgtaaatacc gcacctagag aagctaaaag cattggcaac atgcttaacg
    35281 gccctactgt gcccagcata tctgctgcat catctaaaaa tgtacttggt cgattatctc
    35341 gagaaaagaa catcaagatt agcatggctg caaaaacacc gacgcccacg ccgactaaag
    35401 cacctaaatt ggtaaataga gcaaacaaga tcgcaaagac accgatactc aaagctggaa
    35461 taaaaatttt cattcctagt ttgtctgaca ttttttccat atattctttt gatggaagcc
    35521 ggctttctcc tttgctgact ttcttagcaa ttgctggtat ggtcatcgca aagatcaagc
    35581 caccgttcac gattgccgga agccatcttc ctcctgcaat aactacccct aagaccgtcc
    35641 agaaaaaggc tgacccataa cgatgaggat tggttttatc tgttaaattt cttactccag
    35701 tgtaaatcaa tacgagtccc atcacgatat aaaggatctc cagtaattta tcgcctaata
    35761 aaatatcagg atttgtaaaa aagtccatct tattgcccct ttcctggata atatttcttc
    35821 gctaatttct tttctttaag atagaagtag acacttgcca caactaaagc cgtgatagcc
    35881 actggaactt ccactaaagc aagctgtccc aatgttacgt catatcctag atctttcagt
    35941 gttgattgga ctagcaacgc ccctgctcct ccgatgaata gtacttggcc aaagaaccag
    36001 cagacatttt ccatagctga agccatacct tttagttctt cttcatgctt aggatggact
    36061 tctaaccctt ttgattcgat ggtccccaat gccatcggta aaatgattgg acgaacaaat
    36121 ccagcaactc caccaaaact cacgttaaaa gccgcaaaga tcattcgaaa gatcccataa
    36181 atatctacaa tcataccagc agatactttc ttgaatcgct tgatcaagga agccgctgat
    36241 tctttcagac catttctttc aagcgttcct gttgccaaca taatgatgat aaaaatcgcc
    36301 atcccgcgat tgtttacaaa acttgtacct aaaagttcta acattccttg aatgccaaga
    36361 ccgccagtca aagctgtaac aactaaagca accattacga tcaatatcga gtctaattta
    36421 aatgcaaacc cgagaataac aatcaagacg cctaaaaggc taagataatt ttccatatat
    36481 tttcctccat aaaatgacaa tattttttta attataaagc aaaacacata aaaaatatag
    36541 ttgttttctc acgaaataga cactattttt aaatattttt cgttattttt ttatcacaaa
    36601 aattatctta cttattgtaa ggtaaagctt tttttaattt attgcccgat aatatataga
    36661 aataaggtct agttactgtt ttttttaaat gattaataaa taacaacttc tttctatgaa
    36721 attgcaaagc attcatcttc ttttccgcta acgatatatc cgtcagtgct tggtacactt
    36781 tactaaaaag tatgagattg ccgatatctg gataggtgtg ctatactaca gaaaaagata
    36841 tacaatctgc caccgggtag gataaagagg atgatcattc cattaggtct ttgaagggat
    36901 gattttcctc tttttgtgta tttttttata gttaaggagg aatgtaagta tggcatggat
    36961 ggaattaatc atagcaggaa ttttggaagt attctggtca acgatgatga aatggagtga
    37021 tggtttttct aaaatcaatt attcttttta cacagtgatt ggcatgattg ctagttttta
    37081 ctttttgtca aaggcaatca aaagtttgcc gatgagtctc tcttatccta tctggacagg
    37141 gattggcgca gttggttcgg tcataattgg tgtggtcttg tttcatgata agctgaatct
    37201 ttccacttgg ttctttgtgg ggatgctact catcagtatc attggcatca agattactag
    37261 cggccactag acacttggaa taagtactga tcagaaaaaa taagcctttt tatttaatat
    37321 tcaatttttt tatgaaaaaa taagaaataa gtccaatgac ctagcgactt ctccactcat
    37381 caggtgtatg cttgtactat ctatagaaaa ggagtgaata tttttgaaaa gtctttcggt
    37441 ccaagaatta tccaagaact ttggtcacaa acaagccctc agcgatgtca gttttagctt
    37501 atcccctggc aaaatcgttg gattagtagg tcctaatggc gctggaaaaa caacgatcat
    37561 gaaagctatt ttaggactga tccattactc agatggaaca atctgtattg gtgaaaatga
    37621 gatttctccc tctagtcata aagggttgga acaagtagga gcattgatcg aatacccggg
    37681 tatctatcca ttcttaacag gctatgatca tctgaagtta ttctctgaaa ccaacgatgt
    37741 atctgctatc gacactatcg tgaatcagct caagatggaa aagtacattc acaaaaaagc
    37801 gaaatcctac tcgttgggaa tgaaacaaaa attgggaatt gctcttgcct tactgaacca
    37861 tccgtctatc gttattttag atgagccgat gaacggtttg gatccacaag caacaagaga
    37921 tgtgcgaaaa atcattaccg acttggctac tcagggcacc tctttcttga tctccagtca
    37981 cttactcagc gagcttgaaa aaatggtcga tgagctgatc ctgatcaatc aaggaaagat
    38041 catcaaacaa tgtacaatgg ctgaattgaa ccaaacagcg caagatttca tcgttatctc
    38101 tacaacaaat gatctagctg ctcgaacgat cttgacagaa gctggatata ctttggaaga
    38161 tcctgataaa atcaagcttt taaaagaaaa cgaagaatta ttaggaaccg tgatccagct
    38221 attgtctgca caaaatatcc atgtgacaga cgtccagcat ctgacgaatg atttggaatc
    38281 ttctctattg gaaattctgg attcagtaaa gggggaagaa gaaaaatgac attgcttgta
    38341 aaacaagaat tatttaaatt gatcaagaaa aagtcaactg ctgttttatc tgttctatta
    38401 gttgttttgc tcataggaac agcacttcta gccaaaaaat acacgacgat cattgatcca
    38461 gttgaaatga ctgctcagct ttttagtgcc acatcttgga ttgtctttat catgattgca
    38521 gctgcaagca cgatcatttc gatggaagca caatatggta cattgaaaaa tctcctttat
    38581 cgaaagtatt ctcgaggaga aatattagta agcaaatgga tcacattagt tatttattct
    38641 gtttatttat accttttagc tattattgtc actgtgttga tgaaactgat tcttttccct
    38701 tcgatttcct tcacggagaa ggtttctact ggtcaaacac tgatccaaag cttgttcact
    38761 tatactttgg gtagttatat cggtttatgg ctgattttaa gtttagtgtt gatgattgct
    38821 tgctttatca atagttccgg tgcatccatc tcagcaggaa tcgtctttta ttttgcttcg
    38881 tcaatcatat ctggtatcct tattgcactc atccaaaaat gggagtggat caaatggaat
    38941 ccgatcagta tgttgaatct gcaaaaccaa attggaaacg aagagatcat gaagcaattg
    39001 actcatcttt ctactaatca aatgctattc ggtaatttag cttacatcgt tttgttctta
    39061 gcattaggat atctcgtatt taagcgaaaa aatgtatgat gactcatcaa aaaagaggct
    39121 gtgaaagaga cgttcagcct tattgccgat tggctgtctc ttaaacaccg tttattctga
    39181 aaaaggagct gtgacaacat ttgtgtcaca gctcctttcc tagtatgttt ttgaataaac
    39241 gacaggctca caacctctct ttatacttct tttatacttc tatacgtgaa gcatcccagt
    39301 ggcaaataaa accattgcaa tcactccgac catcgtcaca cctataagta aaatcttatc
    39361 taagtggata tgttgtacag gctcgttttg ctccttacgt gctttgaggt aaaaataaat
    39421 gcctggcaag aaaagaacaa gaacaagcat tacttcatta aaggctacga ctagcatagc
    39481 ccatacttga aaggcacttg ctaaaagccc tactaaaaat tggacccatt ctttccgctg
    39541 ataagaaagt ttcatttggt acaatcctaa gaaaagccac gtgaagaaaa tagctgctgt
    39601 accaagtgtg taagcaaagt tataagcact gtcagtgaat aataatgaaa gtaaaaagac
    39661 attcgtacat aacgtcgtca atacgatagc ataagttggt gccccatttt tgttgagttt
    39721 tccccatgct ttaggcaaaa gtccgtcttc agccatgttt cccattgttt caatcggtaa
    39781 gatcgtccat gagagccaaa caccaactaa agaaatgatc aaaccgccgt tgatcacgac
    39841 tgctccccat ttaccaacca tcatttcaaa cacatagccc atagcaggct gcgccttgat
    39901 cgtttgcagc tgattcatcg tcattgtccc atatggaagc atggaaacca agacgtaaat
    39961 aataatcaag ccgaatatcc ctagaatcgt tgctttccca acatctgatt gtttttttgc
    40021 tcgtgaacct acgacagagg ctccttcaat accaacaaat acccaaagca tcaccatgat
    40081 gcaactcaat acttgactgg aaaacgggat cggctgtcca ttcgcattca atataatgtc
    40141 gctagaaaag ttatcaatga attgttggat cgaaaacgtg ctgatagcta ctacaataaa
    40201 taaaaataat ggcactaatt tacagaatgt gacgatagca ttgacgaaac tagcattttc
    40261 gactccccga ttcactagcc atgcatatcc ccataaaaag actgtactca tcacgatcga
    40321 tgccagattt tgcccacctt caaatactgg gaagaaatat cctaatgcgc tcatcaacaa
    40381 tgttgcaaaa gctacgttgc ctaaccagca tgtgagccag taaccccaac cgctgataaa
    40441 accagcgaaa cggccaaaac cttcttctgc gtaactaaag atcccgcctt ttaaatctgg
    40501 acgtttttta ttgatattat tgatcgacaa ggagagcatc aacattgctg ttcctacgag
    40561 tacccaactg aaaatagctg ggccgccagc cgatccggag atgtccgtca taataccaaa
    40621 tacgccacct ccaatcgctg aaccaattac taaggcagca agtggaatta aaccaattcc
    40681 ttttttctgt tgctctgtat ccatgtaagc atcctccaaa ataaaaccgc ttttatcaaa
    40741 aagtataaca aacctttttt atttttactt aattaataaa aactttaata gaaatataat
    40801 tctaccggct tttttctcat tatacaagca aagcgcctag tccctttcca aattacacca
    40861 ccaaaaaact taaaaaagat gctatactaa aaggaaagaa ttggaggatg atccatgaac
    40921 attttatata tatcgatttc aggaaatacg cgtgcctttg ccaaacatct agcagaatat
    40981 gctgaaaaaa tgcatgcaga agatcctgtc aatcctgaag ttactttaaa agaaatccat
    41041 gaaaatagtg attttacgaa agaaacagaa ccatttttta ctttcgttcc tacttattta
    41101 gacggcggaa atggtttaga taacggtgat acagaaatct tgaccgaaac gatgcgtgaa
    41161 tatctggaac atgaagacaa tcataaactt tgtcttggtg tagtcggtag cggaaataaa
    41221 aacttcaata atcagtattg tctaacagcc aaacaatatg cacaaacatt tggctttcct
    41281 ttcttggcag attatgaatt acggggaaca ccatctgatg tgacacgaat ttatcagatt
    41341 ttagcagaaa acaataaata ataaaaaaga agaagctgaa aaatagattt cagtttcttc
    41401 tttcgtttct attgtttcta tcatattaag ctttgacatc catcacaggt gcttttgctt
    41461 ttgctttacc tgttttttcc aagacaaagt tttttacacg atccatattg gttaccaaga
    41521 cgatcatgga tgtttctttg cctgctgctt tgatcgcttc taagtcagct tctgctacaa
    41581 gcgtatcagg tgtcacttgc tgcccttctg ttactttcac atcaaatggc gtaccgccta
    41641 agtcaactgt gttgattccc atatgaagca agatttctaa accatttggc gttgtgatcc
    41701 caatagcgtg tttcgttggg aagacagagc tgactacccc agtaactgga gaatagatat
    41761 gtccgttttc tggttctaca aagtagcctt cacccatcat cttttgtgca aaaactggat
    41821 cacttgcttt atctaaagaa acaactgttc cgtcagcaac tgatgagagg atagtcacac
    41881 tttcagctga agtttgaggt actacttttt caggcacttc atttactgtg gctgtttcag
    41941 tcgctaattc ttctttttct aaacggtctt taggaatacc gaagaagaat gtagcaacga
    42001 agccaccagc ataagctgcc aataatccaa ggatgtagcc taaccattta ccgtcagaga
    42061 tcaatgggat caaagcggct cctgaaggtc caatagcgat agccccgaca tttccgatca
    42121 ttccgatcac tgccccgccg atacctccac cgatacaagc agtaataaat gggcgtccta
    42181 gaggtaatgt tactccgtaa atcaatggtt cgccgattcc taggatcccg actggtaaag
    42241 ctcctttgat catttctgtt aattctttat cttttttgca gcgaatccat aatgccaatg
    42301 ctgcacccac ttgtcctgca ccagccatcg caagaattgg aagcaatagc gtacgaccag
    42361 tttcatcaat catttgcaca tggattggag tcaaaatttg atgcagtccg aacataacca
    42421 tcggcaagaa taatgtgcct agaacgaagc cggcaaatgc tccaccaacg ccaagtaccc
    42481 agttgatccc accgaccatg ccatcagaaa tgaaacctgc taaaggcatg atgaagaaaa
    42541 tttcaatcag accgatggca atcaatgaaa gagttggtgt aacgatgata tctaccgcat
    42601 caggtactac tttatgcagt tttttctcaa cgattgacaa tagccaaaca gcgaagatga
    42661 cacctaggat cccaccttgt ccagctgcaa gagcttcacc agtaaataag tttttcagtg
    42721 gtgcttccgg attcatccct gtcagcatca caacggcccc gataactcca ccaagagttg
    42781 gtgttgcacc aaaaacttgt gcagcattga tacctgtata gataactagg tagctaaaca
    42841 tcccgttttt caagatgttc atcacatcga tatattgttg ccatgttgct gcatcaagtg
    42901 ttccggctgt gactaagttt gctaaaactg cggcaatccc tgccacgatc ccagtaccga
    42961 caaatgcagg aatcattggc acaaagatat tagaaatgtc ttttaatacc gatttgattt
    43021 tagatggttt ttgtttcgat ttttgtgccg ctttcatttc ttgtgcccgt tcgtttacac
    43081 ggtcttttcc agatgctgat gaatttgctg tagctgtact tacagaagaa agtttttctc
    43141 ctaatttcac gcctgccaaa tcaaccattt gctgtgctac tttgttcact ttcccaggtc
    43201 cgatgatgac ttgaagctgt tcatcttcta ctacaccaag cactcctgga atcgctttta
    43261 attcagagac atttacaaga tcatcattga tgatcttcat acgcacacga gtcatgcagt
    43321 ggacaatgct ttctacattg cccatgccgc ctgccccttt ataaatttgt tttgccagtt
    43381 cttccaaagt cagttcgttt tttgccatgg tcttttcccc ctcataaggt cccttttaca
    43441 aatccgtttg cttcagctaa ttttgcttga gcttcctctt tatcactatt tgtcaaaatc
    43501 atgacgatag ccagcttaac attttgatct gcttcttcaa agtacttttc agctgtttcg
    43561 taatcagctt ctgtcgcttg catgatgatt cgttttgagc gttcgattag tttttcattt
    43621 gttggtttga catcgaccat caagttattg aatactttac ctataccaat catactgata
    43681 gtagaaatca tattcaagat aagtttttgt gctgttcctg acttcaatcg agtagagcct
    43741 gtcaaaaatt ctggacctgc atcgacttcg attgggaaat ccgcgtgttt actgatttcg
    43801 gcttgtttat tgcaagaaat cgttcctgtg acagcaccga tcgattttgc gtaatctaat
    43861 ccaccgatca catatggtgt acgaccgcta gctgcgatac caataactat atcatttttt
    43921 gtcaaattca gcttgattag atcttcttgc cctagctcat aagaatcttc ggccccttcg
    43981 acagctacag tcattgcttc ttctccacca gcaattagac ctatgaccat ttccggttct
    44041 acaccgaatg tcggtacgca ttcagcagca tctaacacac ctagtcttcc acttgttccg
    44101 gctcccatat aaatcagacg tccacctttt ttaaaggact caatcgtgtt agcaatcact
    44161 ggttcgatac ttgtcagttc tttttcaacc gcagcggcca ctttctgatc ttctttgttc
    44221 attagttgaa cggcttgaga aatactcatc tcatctaatc caaaagtttc ttggtttctg
    44281 cgttccgttg ttaggttctc taaattgatt ttgctcattt ttatcttcct tcttttctta
    44341 taaattgata gttcatacca gctttgattt ggttgatcaa tggtagctct tctttgataa
    44401 ctttagctac tacattcact ttttcatccg ctggcaaatc atatttggtt aattggatct
    44461 cacccatata gcgcaaatac ttttcgttat ctaaagtaat agaccctttc atacgcgtag
    44521 ctgtatttct tgctgggata ggcggaatct ctcgaaaacg tgcatctacg cttcgtatga
    44581 catctcttgc atcgtcttgc cgattcgtat gcttccctaa tatatattcg taaaattctt
    44641 catctacagg ttccgtatgg agcaagactg tctgttcttt ttggaaagaa gcaaattgct
    44701 cctgaacgtt ttctgacaga cctgcatctc cgatgtaaac aatatccgtg ttacttgcta
    44761 atagatctag agcgcctgca agaggatgga tccctcgatg ttcttccaaa gttggcaatc
    44821 cttgatatag tgggcctctc aactctgtat ctcctggtac aaaaccttgg acaaggagac
    44881 cttgaatttt gagccattga ttttttttct gataccattc tttgtccagc cctgtttcgg
    44941 gacgtggata ataattatgc caagcttcaa tctgtgagaa atcagcttct gcttctttca
    45001 attcatcgat atctttaggc gtgatcgtgc tagcattcaa actgattttc aattgatgtg
    45061 accagtcggc aatctgctga ttggaaatat gataatccat tcttaaacct gttacaccaa
    45121 ttgctttcaa aggcgttaga tcttctaatg aaaaacccgc tcgttccaat gcctctcctg
    45181 aaatatcgac catcaattct agtttattct ttttcgcttc gcttcctagt tcgatcaatc
    45241 gcttttgata tgccgaaaca tcatcttctg gtatatgcat ggaagtgaaa ataccgacaa
    45301 agccattgga tgccatttgg cggatatact gtttcttctc ttctgacaaa gaatcgttca
    45361 taaatattga aaagccaaac atattatccc tctttttctg tatccgtctt catttctatg
    45421 actagagtat atatctaaag aaacaaaatt tcaatacttt tattaaaata attaaatttc
    45481 atttctaaag gttgagttta tattatcaaa agaattgtca taacctaaaa aaggcactgc
    45541 taagcaaaag cagtgccttg aaatatttta tttaaataac acaaaaacat aattactcat
    45601 aagaaaccaa ttctgtatta tctaccatga atgtaaagaa cccctcatta ggcatcggat
    45661 gaaaataagc attgatcact cttatcaagg cattatggca aactaacaga tagacatttt
    45721 cttcgtcttc gatgcattct ttcaataaag gaacgatccg tgcatacaca tctaagactg
    45781 actccccatt tgggaatcgt acagcgaacg ctaaacgtgc tttttgaaag ttctcatctt
    45841 tgcttggcag tccatcataa tccccaaaat ccatttctac caatcgttca tcaacggtca
    45901 gcggcaagct gagacgatca gcaactgctt gtgctgtatc tcttgctcgt tgaagagggg
    45961 aatggatgat tttcgtgatt ggaacaggca aatctactac cttttctgct agtttctgtg
    46021 cctgcatctg tcctttttca gtcagcggca catctgcccg tccgcaaact aatccttgtg
    46081 cgttccaagt tgtttctccg tgtctcgtta cataaagcat gtgattctct ccttcgttgg
    46141 caaagttccc cttaaccata ccttgttgtt cttgagatta caagggttag attctctcaa
    46201 gagaaataat ctcagtagat actttatcca ggaaggtttg atcatgttcc actagtaaca
    46261 tggcaggttt cacgttcaag atcagttgtt ctaattgttc ttgattgaag acatccaaat
    46321 aattcaatgg ttcatcccat gtatatagtt cagctggctg tgataaagat ttagccaatt
    46381 ccactttttt ccgttggccc atactcatct gctcgatctt gttatgaaaa acatctcttt
    46441 ccatcccaag ctttcggagg ttgttcaaaa atgcttggta gtctacttgg tttttctctg
    46501 caaattccgc caacgttcct cgattgtctt cataattttg gcttgcataa ctaatgctca
    46561 gatgttttgg ctggtatttt tctcctataa ccttgccgtt gaatgccccc agaagataat
    46621 ggataatgga tgactttcct gcaccgttag gacctgaaat cgccacccgc tgatgaggct
    46681 cgattgtaaa atgaattggc tcgaataaca gattttcata ccctaattga agatcttcta
    46741 cgcttaaaag tcgcttatgg tgagacgctt ggctattcat cgtcaaagaa tcgatatatt
    46801 cgatatcttt taatagtttt tctttctcgc tgatctgggt ctccatccga ttcacgattg
    46861 ctttggatcg tttcatcgtc cgtgcagcat cagcacccac tgctccttta ttcactcgtc
    46921 tagattcagt atcgatgaat ccgacttgtt tctttgtttt atctccttct cgggaacgag
    46981 accattcggc tttttcagct gctgttttct ttagcctact gacttctttt ttcaattttt
    47041 cattttgagc catttcaaat tcatcacgaa gttttttctg ttcttcatag atagagaaat
    47101 tcccttgata aagttccagt tgactttttt cgattgctaa aacatggtcc actacttcat
    47161 cgataaatcc ccggtcatgg ctgaccacga tgaagccttg ttttttcttt ttcaaataag
    47221 ccgctacttg ttttctacca gagatatcca aatgattcgt tggttcatcg attaacggga
    47281 aatgagtgtc atccacaaat aaaagtgcca gtaggacttt tgtcttctct ccccccgata
    47341 gtgtgctgaa ttctctccat aagatttcag gatctgtttg catcaattgg agctctcttt
    47401 cgatttccca tatctcaaaa tccgtaatat catttaacac gtaataggtt aaacgttctt
    47461 tatcttttgt ctgttgcggg aaataggcaa attcttgctg atggattact tgcccttgat
    47521 aaggtagttt gttttgtaga atattcagta aagttgtctt tcctcgaccg tttcgtccga
    47581 taagtcctag tttccattgt gtgtcaaaat ttagatttgc ttgttcaaat aataatgtgc
    47641 cttggctgtc gtagccgaat gtcagatttt ttatttcgat tttagacatt ttccatcacc
    47701 tcgtaaaaaa agaccagtcc tattttcaga actggctaaa gaggatgcaa gggttggata
    47761 cacacaaaaa gacccataca tcgaaaaaac caagccaatc ccgaaaatct gcacactgct
    47821 tccttgtctc cacaaggtac agtctgaatg cagctttcat caatcgactt aatttttcaa
    47881 tgcacggatc cctcactttg tcctatattt gaaattacga tagcataaag aaaatgattt
    47941 tgtcaactac ttcgggagga tggtgaaaaa tctgctaagt gtctgtccta agatttttgt
    48001 tttttctaat gtttgcctgt gttccattgc ttcttctaaa cctattggac ccaaatgaat
    48061 acttaagaca attgggagaa aatcagaaag tccttctagc tcttggtctc tacttccgca
    48121 aatagcgatt attggttttc gatatttttt tgcaagcact gctacaccgt atggaacttt
    48181 tccgtggatc gtttgctgat cgatccgccc ttctcctgta atgatgacat ctgcttgttc
    48241 gatctttttt tccaatccag tgatttggct gactaaatcg aaaccagaaa ccatcttcgc
    48301 tcccaacaaa aaaagggctc caccaatacc gcctgctgct ccacttcctg gaatatcatc
    48361 taaatccacc tcccagaaat cttttatttg ctgagcaatc tttcctgctt gtttatctaa
    48421 gaaagctagc gtcgtatcta ttcctccttt ttgtcttcca aattgccaag cagctccttg
    48481 ttgacctgta tatggattgg taacatctgc agcgataatc aattttactt tagaaacaag
    48541 aacgtttctt cgatcaaaat gaagtttttt agtagataat aaaggatttc cttctgtgta
    48601 cccttctaaa gaagcaccca aggattggag taatcctaga ccaccatcgc tacacccgct
    48661 tcctcctaaa gtgacaataa tttgttctac ttcttgaagc agtgcatctt taataagttc
    48721 tcctaaggaa taactggaag caagtcggat agtttgatcc gttggtttat caagtagatc
    48781 taaccccaat gcttgtgcag attcgatgac tgcggtgttt tttccttgcc aagttgtcaa
    48841 taaatagctg atttttcgct gacggaataa gagatccatc ccatcaatgg tacgccatgt
    48901 tcccctgagc gcgtaataga ttgcttctgc agtattttct ccgccatctg caatcggcac
    48961 attgattttt cttcctttac gatcttccca gccatttaga actgcctgat ttagttcaaa
    49021 tgaagaagca cttcctttaa atgaatcaat tgccgccaaa atatccatct gtatccctca
    49081 ctttcttctt aagtaagaca ctttttttca tttttttcaa acaaaacaat gctattttct
    49141 tccatttttc tatatactaa aagggaactc attgaataaa ggagagaaaa aacatgaaaa
    49201 tcgcaatagc tggggccgga gcaatgggca gccgaatcgg attgatgcta catcaaagcg
    49261 gaaatgaggt cctcttgatc gatcgttggc ctgctcacat tgaagccatt cgtacaaatg
    49321 ggttgattgc tgactttaac ggtaaagaag tggtcgcaaa actgccaatc tattcaccag
    49381 aagaaatcat cgaaagcaac gaacacgtgg acttgatcgt agcattaaca aaagccaatc
    49441 aattagatga tatgttttgt tcgatccaat ccattattac tgacaatact tatgttttgt
    49501 gtttactaaa tggattaggt catgaagatg tactggaaaa atatgtgcca aagaaaaata
    49561 tcttatttgg gatcacgatg tggacagctg gtctagctgg tcccggaaaa gtcacattgt
    49621 taggtgatgg agaaatcgaa ctagagaact tggaaccaga aggcgaagca tttacaaaaa
    49681 aagttgtaga agtctttcaa gaagcaaatt taaatccgat ctatagccat aacgttcgtt
    49741 attccatttg gcgaaaagct tgtgtaaatg gaacattgaa tggtttatgc acgattttgg
    49801 attgtaatat tgctgaacta ggcgcgcaaa aagcggcaga gagcatggtt cgaacaatcg
    49861 tatctgaatt tgcttctatc gcagcaaaag aaggaatcat actagatcaa gaagaagtgt
    49921 accaacatat tgcttctact tatgatcctg acaacatcgg gttgcattac ccatctatgt
    49981 accaagacct gatcaaaaac catcgtttga ctgaaatcga ctacatcaat ggtgccattt
    50041 ggcgaaaagg acaaaaatat gatattgcta caccatattg tgcctttttg acccaattag
    50101 tccatgcaaa agaaggaatc cttggcgcag aataaaaggc tctctgatga gaatcagctg
    50161 aatcagcagc tggttctctt tttttaagcc caataaaaga tcaaaaagaa aacacaactc
    50221 tcatgatgcc ataagaattg tgcttgtttg tttcagtaca taatctcttc aaaatgtagg
    50281 ttttttattt gttttcaaca gaggagaggt catattcgta ttgctcataa atagtggaat
    50341 cgttagtgat aaatcgtttt gcccaatttt ctgcatcata aaattccaat agctctgata
    50401 ggattggctt aaatggtgta tgcagaaatt ccggtaattc atctaaatca cgttctcgaa
    50461 gcaaaaaaat attttcagga cgataaaaat gataatgagc aatcgcttga ttatccgtca
    50521 ctagtttctt ttgaaaatac atggattcaa atgtccgcaa agtcactcct tgctgaccct
    50581 cccgcaacag ttccagaatc ccgcgcgatt cccctgtttt tttcaggtac tcttcataag
    50641 taagatatcc aggttgttca ttccctcgat gtggaagaat gaaatagttg gtcgtaacat
    50701 ctctttttat aaattcctgc ttatagcttt ctgctcgttc ttttctccca ttattcgttg
    50761 caccaaaaaa tagatccgtc tttggttcgc tagaagaaaa attcatatgt ttcgaataaa
    50821 atgaactatt atgtttcagc ccaagttctt ttgcttccaa aaaatcaaaa tgataaatct
    50881 catcgattgc cggttcatct tgtgcctgct tcagcatcgc ctcgtgttct gctttgaagt
    50941 gattccaaaa aaataacaca atttttgcat tggtaaatgg gcgcacgcgt cgagccatct
    51001 ccatatcaaa tccataatct aaaaaaacga tcagctgata atttgccaac tgttgtctag
    51061 ctgatttaat gaattccgac tgtagtaaat cttttccgga ccaaacatct aaagagcgga
    51121 tggaaggcaa aaaataaagt gatttatttt ttgcaactag cagtacgtca tttttgttca
    51181 tcttttccgc ctcactttct ctgtcacttt ttcctatgat agcctgttta aatagtaaaa
    51241 agccagtaaa acgtttccta tatttgtatg aaaatttaac atttgtatga aaatatgatg
    51301 aaataaatca ttcttctatt aaaattcgcc taaaagtttt ctgaatagtt gtaattgtct
    51361 gaaaatttgt tatcattagt cattgttaaa tattgctatt tattcttaat ataaattttg
    51421 attgtgaatt taaaagaaag aggtcattta tggaagataa aaaattgaaa aaacaactta
    51481 gctccagaca tatcaccatg ttagctttag gtggagcaat cggtgcaggt ctatttaaag
    51541 gaagtggcga agcgattggg atcgccggcc cttctgtatt gattgctttt ttgattggtg
    51601 ggctgatttt atatatcgtg atgaaaggtc tgggaaaaat cgttttaagc ggtggcgaca
    51661 cgcatcacgg attatctggt ttgatacgcc cttatctagg tgctcattct gctgatttta
    51721 ctgattgggt ctactggtct atgtggatta tcaatatcat cgctgaagct gttgcagctg
    51781 cttccttttt gcagttgtgg ttcccgcaca ttccagcctg ggtatttgtt tttatgttgg
    51841 ctgttttaac tacgatcatc aatctttatt cggtacggtt attcgcagaa acagaatatt
    51901 ggctggcttt tgctaaaatc agtgtcatta tcttactgat catttttgct acttatcttg
    51961 tcggtcagca aatgttgggc acaggcgttt tccctaccct tcagcaattg actgaccatg
    52021 gtgggtttac tcctcatggt atgaagggaa tcatcagttc tttgcttgta gttatctatt
    52081 cttacggcgg ttctgaactg attgctatca cggtaagcga agcagatgat cctaaacgtg
    52141 cgattcctaa agcaatcaaa ggtgtcatgg gaagaatcat ttccttttac atcattcctt
    52201 tgtttttgct tttgattctt tttccttgga atactttagc aggcacgaat gtcagtcctt
    52261 ttgtgatggt atttgaaaaa atgaatatcc catttgcagc ggatatcgtc aattttgtga
    52321 ttgtccttgc tttgttctca tctatcaatt cgggtgtgta tgcatcttca agaattttgt
    52381 tcttccgttt gaaggatcga aaaggttcct ctagaaaact agctgtttta aacaagcatc
    52441 aagtaccgca acgtgctgtt ttattttgta ccagtgttct ttatcttggt gtagctcttt
    52501 cttattttgt cggtgacaaa ttatttggct atctggcagg ttccctttcg tatacagtat
    52561 tattgatctg gatcattatc agtgcggcat cctttgtact ggcactaaga aaaggaacat
    52621 tatgggataa aggaatcagc ttttttgcat tagctgtctt aggattgatt ttccttggta
    52681 tcctgttcac gaactccatt ggggtaactg tattgactgg cctgctttac ctgttcattt
    52741 atttcagtta tcaaaaaaag aatgatgcgt tcgtattgac gaatgaatga aatcgataga
    52801 aaattttatt ttatttatgt ggaatagatg gagctattga agaaaggagt tgtgacaaaa
    52861 gtcttgttgc aactcctttt tccgaataaa cagtctcatg acctcttggt aaacggtgtt
    52921 caaaaaccct ctgtgcaaaa taattgattg ttctccatgc tcatgacatg atagaagaaa
    52981 ggaatgaaaa aaaggagttt gttttaaatg aaaaagtatt ggaagttttt gttgatgatc
    53041 ggtgtttcaa cggtagttat gtttggtatg atgtacttga atgtctatgc gctcgatcat
    53101 atcttcttca gtcgtacacg agtattcatg gcgttgatga tgggtgcagt catggcagtc
    53161 atcatgctgt tgttcatgtg gaaaatgtat gaaaacaaaa agataaatgt tatgatctta
    53221 gccgctagtc ttcttgtttt tgccggttcc ttgtttatgg tacgaagcca aactactgtc
    53281 aacgacacag cttggatgaa ggccatgatt cctcatcatt ctatcgctat cctggcaagt
    53341 aaacgagctg atttaaaaga tcctgaagta aaaaaattag cggaagaaat cattcaggca
    53401 caagaagaag agatcgacaa aatgaaaaaa atgatcaaag aaatggaatg accattatcc
    53461 gtccaaataa aaaaagagga tgttccagaa gttatcagct tcaagaaata agaagaagct
    53521 acttctggaa cgccgtgaat aaggggttgt gaaaaagctg ccctgcatca agtaataaga
    53581 acagccaaac aaaaatagct tctcctattt ttcgtttggt taggcttatt accgcagatg
    53641 caagcttttg aacaccgttt attaagaggt tgtaaaatca gcgttctgac ctgagtatta
    53701 gagagacaaa tggaaaaata gttcctcata ttttgccatt ttttgagcta ataccgaggg
    53761 tcagctgatt gaacaccgtt tatcgagagg ttgtgaaaaa gtcgcttagt ttcgcgtatt
    53821 aagaaaaatt ttgtgaaatg gctttccaca tttttgtata aatttggctt aataccgaga
    53881 aactggcttt tgaataccgt ttattcgtaa aagggattgt gacaaaagtc ttgtcacaat
    53941 ccctttttat gtttttattg ttctaattgc gctgtcttgc ttactgcttc ttgcggtttc
    54001 acaaattttt ttgagattcc ccaacctgtg aaggcactga ccatcgaaaa cacaggagaa
    54061 agcaaactga aaaatacgaa tggcaagtaa gtgagtgtag gaataccaaa tgtacttgct
    54121 acgaaacttc cggcaattcc ccaaggcact aagtagttga ttactgttcc accatcttct
    54181 agcgttctac ctaatacagt tggatcaaat cctgcttttt cataagtttc tttaaatgca
    54241 ttaccaggca gaataacaga taggaattgt tcaccaataa aaatatttac tccgatactt
    54301 gtcatcaatg ttgtaaaaat caaatttggt gtgttcgtca tctttcttga tactcgttcc
    54361 atcacggttg agatcaagcc aaattcgatc aacaatccac ctaatgacaa agttagaata
    54421 atcaatgaca cagtaggcat catactttcg attcctccgc ggctaagcag tgaatcgatt
    54481 tgttggtttc cagtatttga aacaaaccct gattcgatga ccccagccaa cttcgttaag
    54541 gaagtttgtg ggttttgaat aaaaatcatt cctactgcta cagcgatatt caacaaaatc
    54601 gttaaaattg ccggcacctt tttccatgca cacagtaaca ttaaaaataa aggaatcagt
    54661 gaccagattg aaatagtaaa gtttgcttct agaacatcag tcacttcacg aatagatgaa
    54721 agacttgcgg ctttacttgt gtgtcctaaa atcatgaata aaaagaaaga aacaacaaat
    54781 gccgggacag ttgaccacat catatgcttg atgtgtttga acaaatcggc atcaacaata
    54841 gctgctgcta gatttgttga ttcggataat ggagacatct tatctccaaa aacggcacct
    54901 gaaacaatag ctccaacaac cagcgctgga tttaagccta gtgttgtccc aataccgaaa
    54961 aatgcaatcc caatcgttga cataacagta aaggcactcc ctacagcgct acctacgatt
    55021 gcacacacaa caaatacaga agggacaaac cactggacac tgatcaattt gaacccaatg
    55081 accattagag ttggaatgat ccctgcttgt atccatacag caatcaatga accgactaaa
    55141 ataaaaataa agattgggat gattcctggt ttgatgccat tgatgattcc ttcgtgcagc
    55201 caatctgtcg ggtatctttt tatcactgca tacaacatga ccattccgat cgctgctaag
    55261 atcgtgatat taggtgagac ctttaatccg acaacgccaa tcgcaatgcc taaaacaata
    55321 accattaata caagtgttgc ttctaaaaaa cttggtgttc ctttttttcc catgataatc
    55381 tctccttttt tagttgttct tatgttctaa aaaagttaag atatcggatt actccgccgc
    55441 aattcatccg cgattcctcc tttataaaaa taaaaagacc tgttttaaac taaggacgaa
    55501 tgactccgcg gtaccacctt aattaaaaac agatctgttt ttcactttca aacttttatt
    55561 caaatgtatg gactttccat gtaattcgtc aattaggctt gatcggttca cagcgaccac
    55621 cgactttctg aacaaaacac ctaaccgcta ctgcgtgaaa agttgacttg tacgaagttt
    55681 accttccata agatcatttg tcaatgaaaa agaaaatatt ttttcatttt tctgaaaatt
    55741 atttttataa ctttcacaca caagtttatt ttttactaga aagtagcgcc ctcttgtttt
    55801 tttcttgcta ctatttcttg atgttcttgc ttgattcttt ctaatagctt tggctctttc
    55861 aacagatcaa gagctgtatt ggcgagtagt tctgctgcaa tcgcaataga agcaaggcct
    55921 ttgtcacttt tagcagcagc tttgaattct tctgtgtgtc cggcaatata tgtctcagag
    55981 attgctaccg taggctggat tgttggtatg acttggctga catttcctac atcagaagaa
    56041 ccgagacttg ttctttgttc cgtttctatt tcttcatctg gaacacctgc ttcttttgca
    56101 tgctggaaga ataagtcatc aaaagaagga gtaacgatga catcatcaac tgcattttgg
    56161 aacaatccaa actcaaaagt cgtgcccgta cttatcgcag cacctcgtac gatattttcc
    56221 actttttcat atactttatc taatgtttgc cgatttcctg cacgtaaata gaaacgtcca
    56281 gcagcgtaat ctggaatgac gttggcagct actcctccgt ctgtaatgat cccatggata
    56341 ttgacatctt ttggcaattg caagcgtaga gcgttgattc cattaaacac ttggatcaat
    56401 gcttccaaag catttactcc tttttcaggt gctgctgctg catgggaagc gacaccgtaa
    56461 aatttgatgt cgactggatc attcgctaaa gattctgtcg ttttcccata acgaaaagct
    56521 ggatggacgc ataacgctac atcgacatcc tcaaaaaaac cttctcgaac aaagctgcct
    56581 ttagctgatc cgttctcgcc cccttcttcc cctggggtgc catatacacg gatttctcca
    56641 ccagtttcat caatgaattg cttcactatg ctggcggcta atacggagta agtaccaaac
    56701 aaattatgcc cgcatgcatg accaatacct ggtaaagcat cgaattctgc caaaaaggca
    56761 attgtgggac cgggtttatt ggaaatataa cgtgcatcaa aggctgttcg gtgtccagct
    56821 acttcttttt ctacccaaaa cctttctttt tctaattgtt taatcaacgc tgctgaggaa
    56881 taaaactcat agttacttac ttcaggatgt tcgtggatat ctagagcaag tgcttgatat
    56941 tctggtaaac gatattggat tagatccttc aattggtttg ttgagattgt tgttgtcata
    57001 aaaaattcct cctatgctag tcatttttct tattttctcc cgaatgtttc ccatgcaggc
    57061 acgcttgatc cttttgatgt tttctcgatt actttgactg tgtcttctgt ttgataagcg
    57121 tctactattt tttgatacgt tttattgttt tcatcttctt ttcttgcaac gatgatattc
    57181 acataaggac gtgcatggtc atccactggt tctaagaaga tggcatcaga agcaggatta
    57241 aatccagcat ctacagctac accgctattg atcactgaaa tgtctacatc tgacaaagca
    57301 cgtgctgttt gggaagcatc taattcagaa atgtctagat tttttctatt ctcggtaata
    57361 tcagaaacag tgggcgcttg tccttttgcc ttatccactt tgatcaatcc agcagtttgc
    57421 aataacagaa gagctctgcc gccatttgta acatcattag ggattgctac ttttgctccg
    57481 tctttgatat cagctacatc cttcaaagtg ttagaataaa ttcccagcgg tgcattgaca
    57541 gtatttccga tcgatactaa atcagttccg tgttctttat tgtaattgtc taaaaagaat
    57601 tgatgttgga aagaattcaa atcaatcgat ccatctgcta aagccacatt tggttgattg
    57661 taatctgtaa atttcacgta ttccaaatta atgttctcct ttttcaaacg gtctttcacg
    57721 ttgtcccata catctgtatc ttctccaata atccctagtt ttacgatagt ttcttttttg
    57781 tcagttgtat ctgcttttcc ttggctacac cctgccaacc aaataattgc tacaaatgta
    57841 atgactacaa aacgaataat ttttttcatt ttttctcctc cactttcaat gtgtaatttt
    57901 tttaatcagt tgattactga taaattgact taaaaaaact aagattagaa tcaataatgt
    57961 agccacaatc gttacatctg tttggaatcg attataccct ctcgatatag caagattccc
    58021 taatccgcct gcacctactg ctccagccat ggtagtcagt ccgatcacgt tgatgatagt
    58081 caacgccgag acccgaatga taccaggcaa accttctaac aaatacacac gtaaaatgat
    58141 accgattgga ctggttccca tcgcttctgc cgcttcgatc accccaggat caacttctag
    58201 cagtgcgttc tcgatttgac gagcaaaaaa cggaacaact ccaaaaatca atggcactaa
    58261 agctgctttc gcaccaatcg tcgttccaac taagaaacga gtagtcaatg ctaaaagaga
    58321 aagcaagata atgaaaggga tggaacgaat gatattgatc agcttatcaa gtatttcaaa
    58381 tagcagacgg ttagctagta atccattagg gcgtgtcact actaacgtca cacctaagat
    58441 gattccaatc atcccgccaa tgaatgctgt ccaaaaagac atatatagtg tttgcttcgt
    58501 cgcttcgaca aattcatccg gaatcaaata aacattgggc aaatatgttt taaagaaatc
    58561 agtcatttta tcttcctcct tcgatcactt tgatacgact atctaaatcg tttttttgta
    58621 aaatatttat ttttacacca gatttgatca aataatccaa tgcttttttc cgctgtttgg
    58681 tttctccagc taaagtaacg atcaaactcc ctaacggcgt ttcttgtaat aactctacat
    58741 tgccatataa aatattcgct gttacttgat atttgctgta cagatgagcg attagaggtt
    58801 cgttcgtctg atttccaata taacttaatt ccaccagcca tttattggcg atctgatcgg
    58861 caaaagcaga atgggcaatg atcgtttcta atgcttggtc aagatgagta gctgttcgaa
    58921 taaaatcttt ggtcaattct tcttcaggat tgctgaagat ctggatgctg ctaccttttt
    58981 caacgattct tccatcttcc ataaccgcta ccttgttgca gatttctttg acaacttgca
    59041 tctcatgagt gatcaggacg attgttaaac ctaactggcg attcaatttt tttaacaatg
    59101 caaggatctg aagggtcgtt ttcggatcaa gtgcactggt tgcttcatca cataataata
    59161 ccttaggttc attcgccaaa gctcgtgcga ttgctactcg ttgtttttgt ccccccgaca
    59221 gttgtttagg ataagcagat gctttttctt ccaaaccgac aagttccagt agttcattca
    59281 ctttttgacg acgttcctgt ttcgattttc cagaatactt taaagaaaaa tcaacgttgt
    59341 caaaaatagt tcggctttcc attagattga aatgctgaaa gatcataccg atggcctttc
    59401 tttcttttcg caattctttg ggagagagct gactcagatt cgtctgattg acaatgactt
    59461 ctcctgctgt tggtttctgc agcaaattca tcacacgaac taacgtactt ttccctgcac
    59521 ctgagtaacc gacgattcca taaacatcgc ctttttcaat cgttaaatct acagaatcta
    59581 ctgcctgtat ctctttttct ttttgtttga aacatacaga aacatctcgc aattcaatca
    59641 ttaaaattcc tccttatcta agaaaaccac cggagaatga attctccggt ggactttttg
    59701 tatgattaac cttcttattg aacatcactg atcttaaact ctattccaag ggcgtttcta
    59761 taatattctg gatacatctc cttcccacat ttttcacagg taaattgggg aggattgttc
    59821 ggatcatttg caatatctgc atcatctaaa aattttacta catccattgg gattgattct
    59881 ttttcaccac aacttagaca tataaatttc acgttggcgt tcccaatccc agcgaattgc
    59941 tttaaaagtt ttttcttttt cttcttcata ctgttgcctg aattcttttt ggtcaatttt
    60001 tcgattctcc tctcgcataa accgctttgc atggttatct ttcgcatatt taataactaa
    60061 ccttccattt ttgcgcacac tcatcccaac gaattcatag tactcaccgc aacaagaaca
    60121 ttctaaggga ttttcaccaa attcttcggt tattctttct tcccaggatt ttggtcttaa
    60181 ggcctcattc agattgataa acagcttttt tactcgtttc tgatactcct tcatgacctt
    60241 tttcattaat gttttgattc tacgactata gattccatag cgacgaatcg ttttgaaatt
    60301 cttattttga atatggcgaa tcagtgcagc tatgaattcg tctatactca tggtcatcgt
    60361 ctctttagta ttcgttcgtt tgtccatgta gttgaacatg acagtgtcgc catcatacat
    60421 taagattcgg cttaatgcga tcgggccacg cttcatataa cgactgatgt attggagtag
    60481 tgactttaga tttgtcctgc tccttttagg agcatttacg taaaaccctt ctccattgtt
    60541 cttgtacgca gcttgtaatc ttgattgaac tctttgcttg tcccactcac ctaacgttcg
    60601 tctaattagt ttcaatacag catttttcca gtattttctt aacatagaaa aaggtaaata
    60661 atcgtattct tcccaacttc catctcttgt taagccaccc atagtaacaa ccatatgaac
    60721 atgcggatta aattctagtt ttgatccaaa ggtgtggatt gtagctacta tacctgcctt
    60781 cacctttctt ttctcaaaat aggcaagaat aatttttgcg gcttcatcca ttagtccttt
    60841 cagtaaggaa tctcgatagt tttccatcat aaagatttcc cgtaacccct catcgatcgt
    60901 aaagattacg tgccgatgtg tcactttaaa catatcattc gccacaaccg ctgaccacct
    60961 ttggctttca cctgttgcac acgttggaca gaactttcca cgacatttca agggaacaaa
    61021 ctttgtttga tgacatccct cgcagacaaa cagtcggtat cctttttgaa tatctccaca
    61081 atatctaaac ttgtttactt cccgtttgac gactagccga atctttcgcc cgtatttctc
    61141 aacaaagtta tcccaattat ggtgttcgtc aaaaaagatt gcttcgagaa tattcgcttt
    61201 catagtaata ttttacttgt tcaaaaacaa aatgaaaagg gctaaaagac tggtagtgca
    61261 gcctttttag cccttaactt tttatacttt ctttactgtc taaaaaatat gcggcgcaca
    61321 gaacgcgccg catatcggac taagttttat tcaaatttgt cttcgccaac acaatttgac
    61381 gaagagcctt ttctttcagg aagacttcgg taatttttag gagttctacc tattctttta
    61441 accgtttatt ctctttttct aagcgtgtaa tttcatttct gcgaatggat ttcatgactt
    61501 cctctaccga gaaaagtacg ttatccatat ttttcaactt cttgaactca tcaatacacg
    61561 ctattagagc gagcttctag ctatagacta acttctttaa cagaaaaccc ttcttccgtt
    61621 accagtttta cagcggtaat tttaaatatt tcatcaaatg aacgtcttgg cataatccag
    61681 atcttcgctt tctcttaatt tggtgtcaat tttagtataa cccgtccaac ttatttttta
    61741 actaagtgcc cggtttttct tgacaactcc acccaaaagt tagatttttt ggtctaagtt
    61801 ttagggtcgc ttcattacta gaattcaaca agagatgttt tttattttat ttaaattatg
    61861 gggtcagttt ccatttgatt acaaacttct ttgttttctt tttttaaacg caataataaa
    61921 ggttttaatt tcagcctttt taattagaaa atcaattttc ccaaattatt ttctttagct
    61981 ttcttaacga tttctgtcgc aactaccaca tctaatacag ccgaaccaac tgttttgaag
    62041 atcgtgattt gttctccact tgtccgaccg atcaattctt cattgatcag ttggcctagt
    62101 tccccatgat agctgtctct ttgaatatac ccatcttgca gcggtgaaat gaagtcccca
    62161 gcttctttta gaacaccgtc catggtatca aaaataacaa catctgcggc tttgattatt
    62221 tctcgtggaa tttcacacat ttccggtgtg taagcaccga ctccattgat gtgcgcacct
    62281 tttttgaccc actcagcaga gaatgtcgca cgttttgaag tggtcacact tgtaatgatg
    62341 tctgctcctt caacgcattc ttgactggtt tttgttgggc gcatcgttac agaaaattgt
    62401 tgcatcattt tttcagcaaa ttggctggca cgctcaaaat caatatcaaa aatccgaact
    62461 tcttctaatt tacgaacggt caacattgct tctaattgtg actgtgcttg tccgccggtt
    62521 ccaatcagcg cgccaatttt agcatcttct cttgcaagaa gttctgttgc tgctccttga
    62581 acagcgcctg ttcttaattg tgtcaaataa gtaccatcca aacaagcgga taccataccc
    62641 gtttctggat ccaatacgat catcgttgct ggtacacttg gtaagttttt cttgatgttt
    62701 tcaggataca cggaaacgat tttgacacct agcgcgcctt cgccaccttc tacataagca
    62761 ggcatatata agctttgtcc gttgcttttt ggcacatcga tattggtgcg aagaggcaca
    62821 cttgcctttc ctgctgaata caatgacagt gcttttttgt ccgcatcgat ggcttctctc
    62881 attgaaaaac ttttgataat atcttctttt ttaagaaata acatttgaat cgctccttaa
    62941 ttagctgctg taactttttt taattgactg cccaacatcg tatatgcact gtatagtaag
    63001 accaaaatca cgatccattt caggatatag gtatctaaag atttgactag gaatacagcg
    63061 accaataccc ccaatacacc gaaggttgaa gtaaaaagtg tgatttttct gctgtattca
    63121 ttaaatttaa tgaattgaac actgccgatc ggtactgaga aggtacaagc ccccatcata
    63181 ataggaaagg ctgcaactgg attcaagcct agcaagtaga cagttaccat cgttaacgca
    63241 taagaaccaa tgccgatatt gttcaatgca ccatagacaa agagtaaaaa tcctgccaag
    63301 attaattttc cgccatacaa ttcactggct gttccgtttg atggaatcca gttcatttgt
    63361 cctgcaaaaa tcaacaatgc agcaatgacc aatcctatgc cgacaaacag tttgatcgtt
    63421 ttctctggta acttcacgac aaatcttggt cctaaatatg caccgataat ttggcagata
    63481 atacaaacag ctagtgtctt gatccctacg ttgatggcag tgatgtaaga caatgccatg
    63541 acggctaccg gtactacaca ttgggtattc aacgttccgg gtagtttttt catgctgacc
    63601 catttcaact ttggataaag gacggttccg atagcaaagt cggaaacgcc aaatgttgaa
    63661 agaaagaaga tgataaatga cgtgaagggc aacagacgca tatcccctgg ttcttctttg
    63721 aaattttgtt tgtttttgaa aaggtctctt agaaagtaaa taataaaata tagattgatt
    63781 gcgacaatta gtgtcagcaa aatattccga atcataaaaa attcctccta ctagtaaatc
    63841 tttctgattc cctcaaagcc ctcaccatat tttgctttaa gttcttcagg agattctgca
    63901 atcactttta gtgtatatgc atcatgtttg acatattctt ttgctagatt gaccatggcg
    63961 tggttttttg tccaagtgac atcggttgat tgcagttctt cgttaatggt accaaacacg
    64021 acttcttgct catcggcgac gatgttgatc catcttgctc caaagtcagc aagtttgtct
    64081 gtttcaaaac catgaatata atacttttct aagggaagat catattcatg ggtagaactg
    64141 aataaaatca gtacaaactt atcaactctt ttttcagctt gctgcaatgc ctttagtagt
    64201 gaatccgtga aattctcatg ccaaacttga atgagcaaac tttcttttgc gtttttcacc
    64261 aaatgctcta ctttatccag aacatactcg ataccatcaa ctttccacag catttcttct
    64321 tcatcttttt ctttgatcat ccctagattc ttggtaagaa aagaaagatc atttttaaca
    64381 cttttttcta atttctctaa aaactcattt gccgagatgg catgataaag tttaggttct
    64441 gatttattaa cgacaatcaa attctttttt aatagttttt ccaaaatatt atatactttc
    64501 gagcgtggca cacctgagat tttacttact tcatatcctg taagattacc tttttctaat
    64561 agtgtggtat acactcttgt ctccatctct gaaaaatcat attttttcat gatttgaata
    64621 atcgtttcca ttgattaatc ctcactttat ttttagtagc tactacggta acaactataa
    64681 attctttttg attatctgtc aagagttagt tcaataacac acatataata attagcttaa
    64741 aaacaatctt tttattaaaa agaaacatta taatatgaat gtttgtgaaa aaataataca
    64801 acttagtcat tctttacaac gatttataga aaaacaacct ctttaaatat aaaaggtacg
    64861 ggttactgat tacttgtaaa tctttacgtt ccagttttat tctttctaaa aaatatactc
    64921 acttcttttc ttagacttct ttttttgatt ctcctcttta tggtcttgtc cttttttgcc
    64981 ttcaaaatat ttaaataaac ccctttcaaa agcatttcta ggttttggac aataaggaat
    65041 gacttttttc ttcatataaa tacctcattt aactatttga tatcatcaca ttatcaaaaa
    65101 aaataggttt tttattaaaa ctatcttgac ctttcgggag atttcactgt gatttatttt
    65161 tattcccata cttttttcgt tggtcacttt cgtataccta atctaagcga tcatcggcga
    65221 cggtgctttt acaacgaatg gcaggacaaa acaaggggcg gaaaaacttt tttgcctatt
    65281 tcataaaaaa ctttttccta cagcaatccc ttgttttgtc ctaccacacg ttgtgaaccc
    65341 aaagcacgcc gacgaacgct tagctatacg aaaatgacct ccaaaaacaa aaaagtgagg
    65401 tgaatagaaa caaaaagaaa ttgaaatctc ccaaaatgtc gtccgcctcg gagacaactt
    65461 gctgctgaaa atggttggtt aattcattta agtattaaat aagataaatc atcaaattaa
    65521 tcggaaaaat agcatgattg gccttatcaa aaataaactg taaaaactta tatttctatg
    65581 agtggtggaa caatgctaat accaaattaa tttatcgatt acccacctgc acaaaccaaa
    65641 gatagcatta ttaggaaacg aatcaatcag cgaatccagc attataatga ggatactaaa
    65701 aataaagttt tcataattat aaatccgcct tcctacgaaa ggcaccaatg aggtgatgaa
    65761 aaccttagag cgctttcttt ctttttttat tccgtgttac cctttccttg caggtccctg
    65821 gtacactaca gaacccgagg aggtgagtgg cggggctgta tagcggcaac cccgcataat
    65881 tatatggtgt cggtcatccg ttaaggcatc aatgaatggc gcaaacccgt agcccgtaaa
    65941 cttatctctt ccgaagttga ctcgatttcg ccggatgacc agtccctacc aaacctgtac
    66001 tattttttta caggaggttg ctatgttcaa aatctttcgt aaaaattgtt gtggcttgga
    66061 tgtccacaaa acgtggatct atgcgtgtat cggaatcaca gatgcgaatg gtcgtacagt
    66121 gtataagcaa gctcgcttct cttcctttac aaaaggtctc aatgaattag ctgaatggct
    66181 tgctaaatac aactgtaagg atgtgtgttt ggaatcttcc ggtaaatttt ggattcctgt
    66241 ttttaatatt cttgaaaaaa cttgttttgt cacactggct catccgaagt acaccaaacc
    66301 ccagaaagga aataaaacag atcgcaaaga tgcaaaaatg gatttgtgat ctctttatgt
    66361 gcgacatgat caaacccagt tttattcctg gtcttgaaat ccgccagctt cgtgatctaa
    66421 tgcgttatcg gacgaaactg accaacatga aaacaagtga aaagaatcgt gctttaaact
    66481 gcttaaccgt ttctaatctg aaactagatg atgtttttag tgatgtgttc ggaaaatcat
    66541 ccacttctat catccaatac ttgttagaac atcccggtga atcatttgat gttcgaccat
    66601 ttatccatgc ccgttgtaaa actcccgttg aagaaatcca agcggcagtt gagggggcga
    66661 tttctgtacc tcaagcgatt aagcttcgcc aatgcctcaa ccatattaac gagattgaga
    66721 agcatcgaga agagatcaat ctagagattc aagctcttgc agaacccttc tcccctgttt
    66781 tggaactact tcgtaccata ccgggcttag acactcagcc aataacagcg attgcgattc
    66841 tttcagaaat aggaccggat atgtccgtgt ttccaacttc gaaacacttt atttcttggg
    66901 ctggatgctg tccaagaaac gatcgcagtg cccgacgaac aaaatcaaca cgtatctctc
    66961 gtgcagggca gtcgttgaaa ccgctacttg tacagattgc caatgctctt ctcagatcca
    67021 aagaacatcc agaatttaaa aatcgctatc gtagaatcaa agcgaatcgt ggacacaaga
    67081 aagctatcat tgctatttgt aagatgctcc tgaccgctat ctggaatgtc ttatcaaagg
    67141 tggaacccta ttctgctaaa ggatatctgg agccaaaacc tgcgaaagaa gagaaagttc
    67201 tgacgcaatc ccaagctctg gaccttttaa gaaaacgcgg atataccatt atagatagtg
    67261 cttaaaccaa agttacgttg attcttccta aatagactcg ttgtcttcca tttcaaaaat
    67321 tttgaaaacg gtaggcttat ttagtgtacc gttcttcagg tatcttcaaa tagatttatt
    67381 ttcaaactta tttcctttct tcttttactc tcctatagct tagcatttaa gtgggcactc
    67441 gtgtcacctt gctagatagc tatgaatgcc gtaataagcc tcctagtata taggcagact
    67501 gccaattata actgattcaa tccacattat gataaaatcc accttttcgt ttcatatgtg
    67561 ttgaaatatc acatatgtca aaagtgcacg agtcttttca ttcagtgctt tgtaaatact
    67621 caaaattatt ccttttcact ttaaaaaaaa gataattagt acaaaatcag aaatgaggaa
    67681 agtattagga tggactagaa aggagttgtt gaatttgttg caacagattg gtcatttatc
    67741 aattaaaaat taggtgaagt tttattcatc actgcagctg ctgtttccca gagaataaaa
    67801 cgtctagaag aaactggtca gttactgtat tatcaagcag caattgacta cgaacaagct
    67861 tgattactaa ccaaagcgtt tatccacctg ttgattaaat caaatcaaaa atcaggtttt
    67921 tatacgttca taaaagcaat ctccagtgta ctcgaatgtg actgtatcat aggtccttat
    67981 tcgatgttaa tcaaaatggg gtttccttct accgaatcat tggacagttt tatcaatgat
    68041 ttatcaaagt ttggacgaac caacacccaa atcgttttct cgactcttgt ttccttaatg
    68101 gtttatcagt tctggaatgt ttatcatgcg cttttattaa aatagaaaag agcttttttc
    68161 atgcgacaaa gcagtgatca tttattggca catgcaatct ttgtggatcc attttttgaa
    68221 aatacgatat ttagttttga cccaaaaatc tttaaatacg tatttgataa tttatcttaa
    68281 caaccagata attttattca gcaccgtatt atctatattg aattctcgga atcaagataa
    68341 atttttttcc gtttttgttt cttttttaat cttcttcttg ttattaatag tgattaggat
    68401 gatattccta tattgatctt tgataattag atataatttt tgaataacgt tccctgctat
    68461 tcgagctaga aatacaagta cgccatgacc tagttagcga caactactta gagatttctt
    68521 ttgttctggg acaacaaaat gccatgacaa tagcagtaaa taatgatact tccgtaaggc
    68581 tcgccgtaaa ctggggagag gtgaaattcc tatgtgctta cccaaagcgg ttcaaaaatt
    68641 ttaaactatt attttaggag atgattttat aaaatcgaaa gcctacttga ataaaaaaca
    68701 agcctgtgaa tttctaggaa ttgataataa tactttagat aagtggattc gtgtatataa
    68761 ttttccagta ataaaaattg atggcgtagt tcgctttgac gtagaggata tcaaagattt
    68821 catgaataca ttcaaaaaaa attgaaattt tcttctcgtc acatatacta taaatagcga
    68881 aatgtactgc cttacttttt aaaggagtga ggaagtttgc ctacaaagct ttcaaatggg
    68941 aaatataaaa ctaatctgag gtatccaaaa aaattcagag aaatcactgg aattgcatca
    69001 gagaagtatc aaaaagtatt tccaactagg caattagcta ttaaggccga aagggaaatg
    69061 aaaaagaaga ttgaaacagt tttaagagag gagaatgcaa actcactaga attgaaagga
    69121 aaaataaaat ttaaagattt ttatgaatca aaatggcttc ctagatatga actaggtcaa
    69181 actactaggt caaacagggc tccaagtaat gtaacaatta gtaatactaa ggatatattc
    69241 cgattgcaca tccttccaat gtttggtgaa tatgcaatga attatctgaa ttcaaatact
    69301 gagataatat cagatgaatt aacaaagaaa tcgaaagaat acgcaaatat aaaaattatc
    69361 aaaggctatg ttcgctctat gtttgatatt gccgaaatac tatgttatat cgaattcaac
    69421 cgaactacca aaattattca atgtattacc gcgcctaaga aaatggcttt agaagaaaaa
    69481 aggataaggg aagggaatca agcattatca tcagaagagc tgactgattg gatagaagca
    69541 gtaaacaatg acttaaataa tcacttgctt acacttcacg attacacact tttcatgctt
    69601 accttatatc taggtgatag aaaaagtgag acttatgctc tgcaatggaa atatattgat
    69661 tttaataaaa atacggttcg tctcaaatat gctttagata aatatcaaag aaagacacat
    69721 acaaaaggtt ggaaagacac cgttattcag gcaccagaag ttgtgatgac attattaaga
    69781 gaatggaaat cagctcaggc tgaacaattg ttgaaactaa aaattataca aacacctgac
    69841 cagtacctct ttacctattc caaaccttct ggagaagtaa attgtcctgt tcacgctgac
    69901 tacttaaact atcgaatcaa tgcaataaaa aaaaggcatc ctgaattggc tcaattatct
    69961 ccacacaaac ttcgtcatac ctatgcaact atagctaggg aaggtggagc aaatatgaat
    70021 caaatctcta atgctttaac gcactcggat atttctacta caaaaatata cgtgaacaca
    70081 cctgacgtag ttgataaatc tgtttttgaa gcatttcaaa aaggattgaa taagtgtgat
    70141 taacatgtgt tctcaaatgt gttcttatta taaaaaaaga cactttccaa ataattgaaa
    70201 agtgtcctga aatattgata taaaaagaat attaacgttt tgagaattgt gaagctttac
    70261 gagctttttt aagacctggt tttttacgtt cgaccatacg tgcgtcacga gtaagtaagc
    70321 cagcacgttt aagagctaaa cggaagtcag gatcaacttc tagcaatgca cgagcgatac
    70381 catgacggat agctcctgat tgtccagcgt atcctccgcc gtttacgtta acaaatacgt
    70441 catatgcgcc ttttgtttca gtaacagcga aaggttgatt gattacttca cgcaagtcag
    70501 catgtggaat gtattcttca acatcttttt tatttacagt aattttgcca gttcctggta
    70561 ctagacgtac gcgagcaact gcgtttttac gacggcctgt gccgatatat tgaacttgtg
    70621 ccaatgaaat tccctcctat tagattaagt ttgtgatgtc taaaacttct ggttgttgtg
    70681 ctgcatgtgg atgttctgct ccaccgtata cgttcaattt tgtaaattgt ttgcggccta
    70741 aagtgttttt aggaagcata ccttttacag aagtttcgat caaacgacga gaatttttag
    70801 cacgcaattc gccagcagtg attgatttca atcctcctgg gtagttgctg tgacggtaat
    70861 aaattttgtc agtcgctttt ttacctgtta atttcacttt gtctgcattg atgacgatga
    70921 cgaaatcgcc agtatccaaa tgaggtgtga aagttggttt atttttacca cgtagtacag
    70981 atgcaacaac tgttgaaaga cgtcccaatg gaacatcagt tgcgtctact acataccatt
    71041 tacgttctac ttcgcctggt ttggccatat atgttgtacg cacgttattt tcctccaatt
    71101 taagttctga tgtttgacat acacttcgag tttccggggc tctttgtggg gcaaacaata
    71161 ccatttaaca tattacccgc taatctagtc aatgtcaacg tttttctgct tgattgaaaa
    71221 atttatatga aactttactt cttttctttc ttttatataa aagggtcgtt tcctgtcaaa
    71281 atgaaaaaca aaaagaggct gtgacaaaag tcttgtcaca accccttatt ttgaataaac
    71341 ggtgttctcc tgccaactcc tcggtcacaa gtcacaatat ccataaaaca taagaagctg
    71401 ttttttaaaa ttgtttcttg tgactcggag ctgaacggca ggcttacaac ctcttggtaa
    71461 acggtgttca atcagctgac cctcggtatt agctcaaaaa acggcaaaat atgaggaact
    71521 attttgacgt ttgtttctct aatactcagg tcaaaacgct gatttcacaa cctctttttc
    71581 ggtcaagttc aacaacagtt tttacgcgtc gatctctggc gctttgccca aatgagcttg
    71641 gatcatccag atacgttttt ctgtggctgt tttgaattcg ataaagatat cttgtgttgg
    71701 atcgtcgcct tcttctccag aaacttcgat tcctttttgg taaagatctg ctagataacg
    71761 atagcctgca acaagtgttt ccaaacgttc tggaatagta cgatcccagc ggccaatttc
    71821 atcagggatt tttgtgttat ctgcaaattc acgcaatgta gaataaggtg aaccgtctaa
    71881 tgtgatcaag cgttcggata cttcatctaa ctgagcgttc aaatcatcca tgaactcatc
    71941 catcattggg tgcaatgtaa ggaaacctgg tcctctcatg taccaatgtg tttggtgaac
    72001 aacaacagac atttggctta gatctgcaac taattgattt aatacttctt tggtttgttg
    72061 gaatttcatc tttcttgcct cctaacattt tcttacactt aaaataatag tagactttca
    72121 atgaaaagta caacaaaatc atttacctga gaacgatttt cagttcgctt ttttatccgt
    72181 aaagccaatc atttttcaga atcagctaat tcttctcgca gttgagcaaa ttgctgataa
    72241 gtctgtgcta aatgcttttg tgtcgaaaca aataatggat agattttctg atatttttta
    72301 tgatcagttt cttgtactcc aacttgctct ttcaattcta tcaattcctg tgcttcactg
    72361 atactttgga tctttccgat gcttctccag cctaaaatca cagctcctaa tgcggatgct
    72421 tctgtgacag tagggaaaac aagcgggtaa cccagtacat cagccatcat ctgacgaaaa
    72481 atcggagatt gagcaaaccc gcctgtagca cggatctctg tgagctgatt ttcctggcaa
    72541 actcctttta aaatccgata aaggttgaga cagatccctt ctagaatcgc cttcatcatt
    72601 tctttttctg tatgttgccg ctgtaaaccg ataaaactgc caaacgcatc tgcgtcccaa
    72661 agcggtgctc gctcaccaag taaataggga tgaaaaatca gaccattggc acccgctggc
    72721 acaaaagcga tagccgaaag cagtgcatca tatggatttt ctcctttttc tttagcagat
    72781 tgaacgactt cctgtaaaaa tgtatgccct gcccaatcaa agatgccagc accattgcta
    72841 gtcgctcctc ccactaccca atgtttctga tccagaacat aacaaaacgt ctccatttct
    72901 ggatggaact gaggctgagt agtaataaaa cgaagtgctc cgctcgttcc tacggtcaaa
    72961 gcggcgatcg tatcaccaaa agcacctaac cctagattag aaagcggccc gtctgcccct
    73021 cccaaaacaa atgatatatc atttggcaaa cctagttctg ctgctgtttt tgatggtaga
    73081 cctgttactt gataggtgga aggaaagact tgcggcaatt gctctattcg aatgttcaag
    73141 tagtcaagca cttcttctgc ccattggaat tcatggatat caaaatatcc agttcctgaa
    73201 gctgttccgt agtcgctgat cagttcgcca aacaatctat aaaagatata gtctttgata
    73261 ccgacaaaat aagcagtttt tttgaataat tcaggttggc tgttttgcag ccacttgatt
    73321 ttgttcaatg gtgtcattgg atgaatcggc gtcccagtct gccgataaaa ttctttgcca
    73381 agcacggtat atttcagttt ttctgcttcg tccgctgctc ggttatctgc ccaagtgatc
    73441 attcgagata acggtgtttt ctcttcatcc aacaatatca ggccatgcat cgcagaggag
    73501 aaggagacaa attgaatgat tgtgtctgaa ggcaactgtt taattacttc ttttataacg
    73561 gtgcagacac cttgaaagat caattcctga tcttgttctg ccatcccttg tgtttcttgg
    73621 atcaaagggt agcgaaaata agcggatgct gcttcttggg cttcatctgt gaaagcaact
    73681 gctttggttt gtgtggttcc gatatctaat ccgattgaaa cgttcatttt ttcacctcaa
    73741 attttatgta tgtacaaaaa tttagtttaa gcttgcgtat cttggttttg aaaaggggga
    73801 gatggcgtgt tactttattt tatcattggt tgctgtatcg gatcattttt atgtttaacc
    73861 gcccagcgga ttccgttagg tcactctatt atttatccta gatctcattg tgtcaaatgc
    73921 tgtcgttcgc tttcttggta tgaattgatt ccgattctct cgatcatcgt ccaacgattt
    73981 cgctgccgct attgcaggtg tcggttgccc ttctactatt tgttggcaga agccttatgt
    74041 ggtggtcttt ttgcctggtt ctttactttt tcttccgcaa gaaatttttc gacgttcata
    74101 tggatgcttt cggctttgct attttcgttg atggatttat tttacttcat ggtccattct
    74161 cacacgctat tctgttcttg ggcaatttta tggatttttt ggttgcaggc cggcgtcttc
    74221 caatggcaaa gtgtgctgtt aacgtttatc gtaggcggtg tgtgccttcg ctatggtcaa
    74281 tcctatctcg gagctggcga tactctgttg atgctttctt ggagtggtgg cttgtctcta
    74341 gaagagttgc ttcagatctt gtttcttgct agtctgtttg gaatatccgt tttttctgtt
    74401 tactttatct gtcataaaaa aaagttggaa aagctgcctt tcattccttt tttgagcagt
    74461 gcgttgctga ttgtccttca tcttaggtat tgaaaaaagg ttgtgacaaa cgacttgtca
    74521 caacctctga tatatagtgt tctcttacca aatccttgtg acttggagct aggcgacagg
    74581 ttcacaacct ctccactaaa tggtgttcaa tcagctgacc ctcagtatta gctcaaaatg
    74641 ctggttttac aacctctgat atacggtgtt ccataagtag ctttttcggc ttcttatttc
    74701 ttgacgcccc aatgtcgacg aaggaaacct gcacgtccag aaccttctcg ataaagattg
    74761 taatggagct tgtttttctt gtaataatcc tgatggtaat cttctgcagg ataaaattcg
    74821 cttcttggtt cgatttttgt cacgattggc ttatcgaatc gcccgctgtc ttgcaatgct
    74881 tgttttgaac gctctgcaat atttcgttct tcttcatcat tatagtagat cactggacga
    74941 taagaatcac cgcgatcagc gaactgtcct aatgcgtcag tcggatcggt ttgctgccaa
    75001 tagatttcca ccaactgatc ataagaaata acttctggat catattcgat ctctactgct
    75061 tctgtatgcc ctgttgtgcc tgttgttact tgttcataag ttggatttgg tacatgcccg
    75121 ccagtataac cggatgtcac agaaatgatc cctggctgct cttcaaatgg tttgaccata
    75181 caccaaaagc atccgcctgc gaaaactgct ttttttgtca tataaaatcc cccttttttc
    75241 tcatcatacc ttgatttcca aaaggaggat aacgttttgc ttgtgacaga aaaaacggaa
    75301 actattatat acgtgatacg gcttctgata aatgccaaaa cgaacgtact tgatcaaaaa
    75361 cggttaaatc aggaatcaca tattcagcag aaggaagatt tatgttttca cctattccca
    75421 atacatgcat gttaccagcc aaagctgctt gacaaccagc ttctgaatct tcaatgacca
    75481 agcatgcatt tggcggtaca ttcaattgct gtgctccttt gagaaaaact tctggatcag
    75541 gttttgcttt tgatacttgc gtgccgtcaa taaggacatc aaaataactt gtcaaattcg
    75601 ttttttctaa aatgaggcgt gcatttttgc ttgctgatcc caatccgatc ttgatgtttg
    75661 tttttttcaa gtactcaaga acagctattg caccaggcaa aacggatgtt tcatccattt
    75721 tttgaatcgc ttgaagatat agattgtttt tttgctcagc aaaggctgat ttctcttttt
    75781 ctgagaattt ctgttccatt tttccaaatg acagcaatcg ctctagtgac tcggttctgg
    75841 atattccttt cagttgctcg ttttctttct cagtgaatgg aatggacagc tggttagcta
    75901 aaaccagcca cgcttcgtaa tgataacgag ctgtgtctac aagaacgcca tctaaatcga
    75961 atagtgctgc tttgattttc atcgattacc tccttgaaaa tgaacgactt gaagtaaaga
    76021 tgcgatgttt ttagctgtgc gatgaagatt atcagtggct tgctgtaaag cttcttgtaa
    76081 aggcacagct gcaggaagga tcggaaaaac ggccgaaatg ccaacatctg ctgctttttc
    76141 gcttccttta ccaacacttc cgcaaatagc tatcacagga acgccctctg gtactcttct
    76201 agcaatccca actggcgctt ttccttttag actttgtcca tctagacgtc cttcgcctac
    76261 gattacgagg tctgcttgct gtacccgttt atcgaactcc agtaaatcca atacgtagtc
    76321 gatgccagag actattttcc ctgaagcaaa tgctaacagt cctgcaccca ttccaccacc
    76381 agcactactg cccgatgcct cgattacttg aggggcaaat ctcatataaa aatcatgcat
    76441 ggcttggtca gccactgcta attcattttc tttcaagcct ttttgtggtc cgaaaacaaa
    76501 agaagcgcct tcttttccgc ataaaagatt agtaacatca gtaatgacag tgattttggc
    76561 tttaatcagc tcaataggca cgttcgtttt atcaactgta gcaattttac ctagattttc
    76621 tcccagtgct tctacttttt gattatcttg atcgtaaaaa gcataaccta gaccttctgc
    76681 catgccgatg ccgccatcgt tggtactact tccgccaacg ccgatgatga tgtgtcgaac
    76741 accttgttgc aacaattgtc gtatcagttc tcctactcct cgcgtggata acctaagtgg
    76801 ctgttgttgg tttagtggga catctttcaa tccgacgatt tctgccattt caaaaatcgc
    76861 agtttgaccg tctgaagcgt actggatttc tttgtttttg ccaaatgcat tagtaacgac
    76921 tgctgtttgc cgcttcaacc ttaaactgtc tgctaatgat gaaaccgttc cttctcctcc
    76981 atcgcctata ggtagcagat catattcagc ctgaacaaaa acttcttgaa aacctgattg
    77041 aatggcttgt gctgcctcta aggctgtcag actttctttg aaagaatctg gcgcaatcag
    77101 aatacgcatt attttcccct ccgttccaag atcagttctt tttccagctg gtattggtct
    77161 ccattgacaa aaataggtaa tgtttctttc gtctcttttt ttattactat ttgttttttt
    77221 gtcaaaacaa atagcaacct gtgatttttc caaataaaag gaaaagaaat tttttcccat
    77281 gctgaaggaa gtcttggaga aatagaaaga gttccattcg ttactgtaat acctgaaaaa
    77341 ccaaatataa ctgctagcca tagtgctcct aatgaagcag catgaattcc gtcatctgat
    77401 gaatgcggat ctggtcctaa atcaatcagg cacgcttctt ggaataaatg atacgcccat
    77461 tccatttctt ggatacggca agcctctatg gcgtgaatcg ctttactcaa cgatgagtcg
    77521 tggattgttt tgttttcata gtaatgcaaa ttcttagaaa cgattggttg agaaaaatac
    77581 tcaggtaata agtataacag catgacaaga tctgcttgct tgctgacttg gagttcattt
    77641 acttcgctac gggcataatc aagtaaaata gactggctgc caggacgttc tttgtaagtg
    77701 gtcaaatcaa taactggctt actgagatac gtgtcatctt gcggaatcag ctgttctttg
    77761 ttaggcactg gcaaatataa cttatctaaa aaattttgac attctttcaa aaaaagcgga
    77821 tcgccagctt gatatttaac agctaaggcc acattataat gcgccagata gttcgtatat
    77881 gcattattgt cgatatattc tgtgtattca tctggaccaa tgactctgtg tatctctaaa
    77941 tgatcatcga cttttacagc tctgctcagc caaaaagctg ctgtttcatg aatgagcgtt
    78001 tttccctttg tttctaaaaa cgattgatcc tctgttgctt ggacatactc ttgaacggca
    78061 taagcaaggt ctgcactgat atgatgttct gcggcagctg aagcaacttc ttgtcttgtt
    78121 ccggttttga tattcaatgc agcaaatttg ggtgtctctt cctgaccagt gtgtgcgctt
    78181 tcccatggga aaagtgcacc ttgatagtga taatctcttg ctttttgccg tgcgccttct
    78241 aatcgatcat aacggtacag cagcaaattc tttgctactt caggaaactg atataaaaag
    78301 aaaggcagga taaaaatttc cgtatcccag aaaacatgcc ctttataacc ttcgccagtt
    78361 agtcccttcg cccctacact aacacttgga tcattgcggg gagtcataat ctgtaaatgg
    78421 taagcagcga agtccatcgc taactgatcg aaagaagaat cgccttggat cgttatccga
    78481 tgctgatgcc aaaaatctgt ccaataagac atcgactgct ctaaaatttc tgtataacta
    78541 acgcttttct gggcttgggc aatacttttc ttaaacgggt ctgtttgctg aagagaggta
    78601 gagagcacga tgatcttctc cagcgtaaag gacgtatttt ttctgatctt ttctgaaaag
    78661 gaagcggtga tccggcgatt ttttgcttgg aatacacctg ctttattgaa tttagctgca
    78721 atcccaatat caattttact ttctgttgtc tggtaggatg cactgatcaa atcgtcacca
    78781 aatactcgca gttctttttc aaccaactgc tgtgtaccaa aattggtttg ctgtccatcg
    78841 atacccgttt tcacatctac ttggcagtct tcggtcaacg gcttgatgac cactttcagg
    78901 gctgcctgat ggagattatt ttgatcagca acacgacaag taatgacttc cacttttttt
    78961 ccttgagcag tttcaatgag cgcatagcgt ttaagctctc ccatttctaa atctagtgcc
    79021 cgctcgtatg caagaacttt catcgtctca agagaaaaat gttcaccgtc gatttttatt
    79081 tcccatctga tgacatctgg gagattcact aactcggctg attctgctcc taaaggtcgg
    79141 ttatatacac cagctgcaaa cattcccctt acttgattcc gatagtcttc ctcctggctt
    79201 cctctgatac caaaaaatcc atttccaatg gtcatctgac tcgcatactt attgatatac
    79261 tctaaatcaa actgtttttc ttctactttc ataaggtaat aacttctcct gtttctgccg
    79321 aacgatataa attttccacc agattctgga tgacatatcc ttgccagcca tctgcaatca
    79381 tctgagtctg gtcaccgagc gcccgattca caaaatgagc catacttagt tcatgtgggt
    79441 cattaactgg cgtggtcttt tgtaaggaaa ccagctttcc atctacatct tcgaatagtt
    79501 cgcctggata cagattagca cctgcctgat cgccacaaaa agccacattc agtttgtctt
    79561 ctctgatatt caaagcaaac gaagtattca gttggatgat cttgccgttt tctaattcca
    79621 gtgtgccaaa aattgcatct tctactgtga atttgcttgg atcccatttc ccgaatttcc
    79681 ctgaattttt tttcgtacca attttttgga agctgtacgc ccgaacgctt tttactttag
    79741 gaaatccagt aatatacatc gctgtatcaa gcatgtgaat gccataatcg atcaaaggcc
    79801 cgcctccttg aagttctttg tcgataaacg ttccccagcc tggaacacca gaccgacgaa
    79861 gcgcattcgc ttctacgtaa taaatatccc cgagaacatc aagatgattc ttgatcattg
    79921 ttgcttcgtc agaaaaacga tgctggaatc cataagccaa aatctgcccg tttttatcgg
    79981 ctgtctctgc catctttctt gcttgatcag ctgtcatagc tggtggtttc tcgcacatca
    80041 ctgaagcatt agcttcgagg gcagccaata catgttcgaa gtgaaagcga ttgggtgtac
    80101 agacactcac gatatcggga gaaatctcat tcagcatttg tgtaactgat gtatacgcat
    80161 gagaaaatcc tgtacgtcgg caaaagtctt ctgctcgctg gctgactgga tcaaccacag
    80221 cggccaattc taagacatct gatctttttt gataataagc agcatgtact ttttctgcta
    80281 cttgtccagc gcctatgatt gctactttct tcatttattt ctctctcctt tgcttattta
    80341 cttattgtta ttctttctct attctttctc taaatcattt aaatgacgcg ctgtttccag
    80401 acagtttttc aagtattgca atgattcctg ataaattttc acttcatttt ctcctcgcaa
    80461 acgacattca tataccatat aaccttcata ctcattttga agtagcgttt gaaaatggcg
    80521 agtaaaatca attgcgccag atcctggttg gtagcgatga ttatctgcta aatggatatg
    80581 acccacatac tctttttgcg tagtcaatgc ttttgaaata tcatcttctt caatattcat
    80641 atgataaaaa tcagcgatga tctgcacatg tttcaattga ttagagtcaa tgtaatgacg
    80701 cgcatccgct aacaaattga tcatatggtc ttggtatcgg ttcaaaggct ccaaataaat
    80761 aaccgtacct gtttcttcgg ctactttatc taaataacga agtgattcgc tgactgcttt
    80821 atagtctcct tctttgcttc ggggtgaaac catcggcggt aatcgataag tgaacattcc
    80881 ccaagctgct gggataacga ttcctttgcc tccaacctcg cttagtgcac gcaaaatctc
    80941 agcaatttga cgtacaccat taagacgccg ttcttcgata aagtcaccga tccacccatc
    81001 gtagccgtta caagctgtca ctactgggat ccctgtttct ttgattgcct gtttgactgt
    81061 gtcgatattt tctattaaca acttaccgtc gatttcgtat tcttcaaatc cacagtcttt
    81121 gataaatcta aatttttcta aaatgtctct tgggaaaaat gcttgatctt gcgtaccgaa
    81181 tttcattgtt ctcctcctcg gacttgaacg cccattttga tactttcttc tgggtgctgg
    81241 tctacataac gcatgtaagc ttctgcgctt tctgcaaatg gcacaactgg atcaatgatt
    81301 tcttcacaat ccaagtaacc gttcatcaat aattcccaac atgtgtcctc gattcgttta
    81361 cggttccatc ttgggtaatc tgggtttggt tcactagatg ctcgagcaaa gacgattttt
    81421 gcattattga aatgtgcttc gcgaccaaga ttaaacccag ctggaaaagg tttagcaaag
    81481 gcaacataag aaatgatccc gccatagccg atccctatta aagaagcttg taatgcggca
    81541 gcactgccac tcgtttcaat aactgaatct actccacgtt tatctgtcaa ttcctttaga
    81601 cgaaaaccga catctgcttt cataggatct agcgtgtaat cggcaccgtg tttttctgct
    81661 aattctctac gctgcgctat gggatcgatc ccaacgatgg tagtagcacc tgctttttta
    81721 gctaattgaa tcgcaatttg cccgatagcg cctaaaccga agattgctac agcatcacct
    81781 gctcgaacat gtgcttcccg gataccacct aaagcgaatt gagcaggatc gtaacatact
    81841 gcatttttcc attgatccaa ccgatcaagt ttacgtagtt tataattatc aacaccgttt
    81901 gtaatcagcg tttcacgaat gggtccataa gtgcagacta actctccttt ttgatactct
    81961 gtcaccaaac tgcccgtttc ttcgatcgta ccgacaatca tatttcctaa ttgaaattcg
    82021 ccaaatacca caccgcgttg gcttccttct tctcttggca agaataggcg ccattcttct
    82081 gaaaattctt catcgataaa tggacttaat cctctaaagt cgacaatttc tgttcctggt
    82141 tttggagtag cgaaaattac tcggatacgt acttcgttct tttcgatctc acggtcttcg
    82201 taatctttga atccggctat tcttggttct aatgcaacta attttttcat cttttctttc
    82261 ctctttcttt tctttttatc cttttacgcc gccttcgact aaatcacctt taataaatcg
    82321 ttcagataac gcatacataa tgatgactgg taaagcggtc accaatgaag cggccatcat
    82381 tcgtccccaa atgtagtctg gtgtactgaa taatgtgttc aaaccgattg gtaaagtaaa
    82441 tttttcggag gtcgacagga aaatcgaagc aaataaataa tcattccacg aaaccataaa
    82501 gcaataaacg aagacagaaa tgattccaga aatagccaat ggtataatga tccgaataat
    82561 gatctggatc cggctaagac catcgatcat tgctgcttct tcaatatcag tcggaatcgt
    82621 gtcaaaataa ctttttagca tgaatatcgc agtaggaagt gtttgaacga ccatcgtgat
    82681 aatcagtgct gtattggtat catacaaacc tagaccggaa atgattttaa ataatggaac
    82741 aacgatcaaa ataccggaaa acatataaac ggtgtaaaag ctagcattga ttttcgagcg
    82801 agctttgaag cgtagttttg acaaagcgta tgccccgctg atcccaatca ctactgcagt
    82861 tacggaggct atcaaggaga tcactaaact atttttgaaa tacatgatga atggaaaaat
    82921 ctcagcattg aaaatatcct gataatgttc aaaagtccat tctttcggaa aaatagtttg
    82981 tgtcgttgca attgcttctt gtgaatcctt gaatgatgtc atcagcatga tcaaaaatgg
    83041 aaacaaattg acagctaata gcaacaaaat cgtcgcgtaa aataagattt tcctgctctt
    83101 tttatttttc atttcaagtc caccttcttt cgtgagagca agacgaccgc tgcaataatg
    83161 atgaacaata gaatcgatat agctgctgct tttccaagat cattgaacgc aaaggctgtc
    83221 tgatacaaat aaacgcctaa gatattgact ttattcgtca gtagatagac atctgtaaac
    83281 atatagaaca tccagataga tcgtaaaaca atcacagttg ctagtactgg tttgattgcc
    83341 ggcagtgtca cgatcttgaa cttctgccaa gcatttgcac cgtccatttc agctgcttca
    83401 taaagcgttt tgtcgactgt ttgcaaaata gccaaaaatg aaataaacgc atacggatag
    83461 tatctccaga tagcaaacaa aacgaccata aagaagctag caactggctg gtcgaaccac
    83521 agcggtgctt cgttgaaaag ctgcaaccta tctactaaca gatcattgac gattccataa
    83581 ctattattga acatatattt ccaagcaaaa atcaaagaaa tagatggcgt aacataactt
    83641 aataaaatca gtgaacgcac cgttttccta aatctgaact tgcggttaag caaaatagct
    83701 acggctaatc ctaaagctgt actgcctgct acaactaaga atgtgtaagc aactgttaaa
    83761 cctaaagaac gataaaattc actatcactt aaaatttcaa gataattgct taatccgata
    83821 aaaacggcgt ctgagttagg attcagcggc atatcgaaaa aactgatctg aatattggaa
    83881 agcattggaa tcagcactaa aacagctaat aaaagcatgc ttggtgctaa aagtcccatg
    83941 gctaatttta agtcagaatg tttccttgga cgattcattg aaacctcccc ctgataatct
    84001 gccaatagct atctactttt ttcgaacacc attggcagaa cttcttgtta tttcgtattt
    84061 ttttgtgcgt cagctaaagc ttgatcgaca tcttcgtttc cgacagttac ttggttcact
    84121 gcttttccga tcacacctga gcttgtgata tctcccattt tcgtgaaatt cttttccccg
    84181 actagtccaa agacttgtac ttcatcaaaa gcactagcaa tctcagatgg cagctcgcca
    84241 aaagacttga tgacttcatt ttctttgtaa ccatccagtt cgactacttg tttattcact
    84301 ggttgagcac caccaggaga catcaagacc cacttttcca tgtttttcgg ttgagataag
    84361 aaagctgtga atgcttcagc agcctctttt tgtttctcgt ctagaccaga agaaatcgtc
    84421 aatccagata ctgtgccata gacagcttga tctttttgtg ttgggatagc aaaaccgata
    84481 ttttctgagt tccccgcttc ataaacagaa ggcaaaatgt aagttgaata gattgccatt
    84541 ggtgctgttc cattcatgaa agcatctttg atttctgtca catcattaga gcctggcatc
    84601 gtgtattggg ataagttttg ataaaacgac aatgcttctc tcatcttttc cgtatcgatc
    84661 gttacctcgc cttcatcatc caaaacattt gctccatttg acaaagcaaa ttgagagaac
    84721 gcttgctcac tcattgttcc ttcagcagta ggcatagcaa ttccatattg tttattctct
    84781 ttatctgtga aatgttgagc aatttttaaa atatcatccc aattttctgg ttctgaaaaa
    84841 ccagcttctg ataatttttc tttgtcatac caaatacctt gaacccagcc gctaattggt
    84901 gcagcaatat agctttttcc atcttctgaa cgaacaaggt ttttggctcc gtcataataa
    84961 ttatcttctc cagcttcctc gataacgttt tggactgccg tctgatcaat cagttcatct
    85021 ttatccatca ctttagcaaa atcctgactg acttccatta cttctggtaa tttaccggaa
    85081 cgagctaacg taacgatttt tgtattgaac gctgattctt ctaccggcac ttgcttgatt
    85141 ttgatgtctg gattttcttt ttcaaaatca gcaaccagtt cattgatcac acttaatcgt
    85201 tcctgttcga cagaagagtg catgaattga atcgttgtct gttgtgattc gttagagctt
    85261 tgactttcac cacaagcagt aagaagaaat ccagtagcta gcagacaggt agtaacaata
    85321 atttttttca tttttttcca cctcttattt tattattttc agccacatat attcatacgg
    85381 ctggaatatc aactttcgtt cttgactgca atggataatt tgtccagaaa acaggtctag
    85441 gtaatctcct tttggtaaaa gataacctgc tgattgattg gaaaaattat ggataactaa
    85501 gactttctct tccttcgctt cgcgaataaa actgataaaa gaatctgctg agtccagtaa
    85561 gtaaatcaaa ctattcggat ggaaggcttt ttcttttttt cgaatagata gcatctgggt
    85621 caattcacca tatactgctg ttcttaatgg atctgtctgc aactctttct caatatctgc
    85681 taacaaaaat ttttgccgat tgatttttcg attctctcct gttttttcta cgcctttgta
    85741 atcatttcga cttcccagca cactttgaat ataaattgcc ggcacgcctg gtaacgttac
    85801 caaaaatgaa tgagcagcta aaaagcgttt gcttctccat tccgtcgtat ctgttggaga
    85861 acttaacgca tctagatacg tagcgtttat ctcatatgga ctggtcgttc catctgggtt
    85921 tttcttgtag tttactcggg caccctcttt cttcagctgt tccactaatt caaggatcgt
    85981 tttttccggc agaatacctc gtaccggatt caatccgata ccgtcatggg aggctaaaaa
    86041 attaaaaaaa gttgtttttt tcgatgcgaa atcgatggtt tttaaccatt ctttcaactt
    86101 acttgtatta cccgaacgaa tcgcttgaag ggtcaaaggt ggtagcgaaa actgatagac
    86161 catctgtgct tcattctcgc cattcccaaa ataactgata ttatctttgt gtggcacatt
    86221 tgtctcagtg atcaataccg ttcctggagc tgcttcatca gcgattgcac ggaataattg
    86281 gatgatttta tgcgtttctg gcaggtgtat acaagaagtt cctagttctt tccataaaaa
    86341 tcccacagcg tccaagcgaa taaatgaagc gcctttttct aagtaaaaca aaagaatatc
    86401 gatcattttc aataaaactt ctggattttt aaaattcaag tctacttgat cttcgctaaa
    86461 agtcgtccat acgtgttttt ctttcccgtt tttgtcaatg aacgttgtaa gtaacgggct
    86521 ggtccttggt ctagtcacgc tgcttgtatc tgtatccagt ggcaaatcaa taaaaaaatc
    86581 tttgtacgta tcattcaagt ttaaatattc ctgaaaccaa gtactttcgg cagacatatg
    86641 attgcagaca aagtcgaaca ttaaccgtgt ttcgcttctc atttcttcta tatcttccca
    86701 tgtgcccaaa cggtcgttga ttgcctgata atttacaacg gagaaaccat catcagatgt
    86761 atatgggaaa aatggcaaga aatgtacaac tctaaatgta tctgccaaat acttttgata
    86821 aaatttctta aatgtacgca aagttggttg ctgctcttca aaaaattgat ccccataagt
    86881 aatcaagaaa atatcttctt cgtcccaatg cagtttgcct gcctggcctt tcttctgctg
    86941 ataaacactg actttttgtt caatcataga ggcggttttc tcagacaaat ctgagtcgcg
    87001 ataaatcgct tgtaaaagtt ttgtatacat cggattcccc tttctttttt gggagcgttc
    87061 ccaacgattt gatcatatta tggaaaacgc ttactgtcaa tagcattttt ttaaataatt
    87121 ttgatataca caaaaataca aataagaaag cttatgtatc aataattaat agcttcttaa
    87181 aaaaatatgg tctctcatga tcatgcaagc tattcctaaa ttttcaaaat catagacaaa
    87241 aaagaatgtc tattgtacta tggaattatt ctaaaacgct cccaaaaagg aggtgcatat
    87301 aaaattgaaa cctactattt atgacattgc gaaaaaagct aatgtctcaa aatcaactgt
    87361 ctccagagta ttaaataacc agccaaatat ctctgataaa gcaaaagcaa gtgtacttca
    87421 agcaatcaaa gaattgaatt atgaaccgag caaaattgca agaggactgt caggaaatgg
    87481 ttttgacgcg attctagcat tatctcatcg tacttctcat acgacctatg gcaatccttt
    87541 tttttcagat gttattcaat ccatttctgc cgtttctgaa caaaataact tcgacttgat
    87601 tctacaaacg gcaaaaacac cagaagaaga gctagaaaaa tgcgcgaaaa agatccaaga
    87661 aaaaatgatc cgaggaatta ttattttaag ctctacgatg gatgaaacac ttctttttga
    87721 attggatcaa tacaatattc ctattgtggt aatcggaaaa gtcggaaacg actacacgaa
    87781 catctactca gtggacacgg ataatttcca ggatagttac gatttggtgg aaacactgat
    87841 caagaatgga caccgtcata tcggctgtct ccatgctccg acagaagttt atgtatccaa
    87901 tgatcgtctc aatggttacc gtcaatgctt atttgatcac cacctagata tccgtaatga
    87961 atggattata gacggcggct ttcgcttaga agatagcatg gcagcaatga atgatttaat
    88021 gaagctacga gaaagaccaa ctgcgatttt ttctaccgat gcattaaaat cattgagtat
    88081 ttacaaagtg gcagaacaat ctggaaagca gatacctgat gatctttcga tcgcaggatt
    88141 cagtgatccc ttattgtcct ccctattttc gccacagttg actcggatag acattccgac
    88201 aaatcagtta ggaatcaaag ccacagaact tttattccaa ctaatccacc accaataccc
    88261 tgaagaaaaa agaatcattc tttcaaccga gattactctc acagattcga tccaacaaca
    88321 agaaatgtag aacagaatta taaaagaaca gaaacactga ggataagtca gttactctgt
    88381 tcttttttca atcactcatc cctcgttacc ccctcccggt attttagcga atttttctta
    88441 ttttccatct gttttagata gctgtggata actataatgt ttgtgttaaa ctattttttc
    88501 cacagggaag aaaaaactat ttttaaccac gttgtgtata agtttttata gttcgttttt
    88561 ttaaacacat ttacccttat ttcaatccat gttatttggg gatacttatc tctaaaacat
    88621 aaatagaata acagacatgt ctactggttt tgttttattc gaggaattat tcaataatag
    88681 ctagcaaaat attaaaaata accgctctat cttcccatca atttattttg cattcaaaaa
    88741 atgatctatc tttacttttg ttgattgact tctcttggaa gatgatcgtt ccgatacctt
    88801 aattggatac gaaccgatgt tgttaagatc ctttcccact tttcttctag ttagacaaat
    88861 tattttagac aaaccaaaaa agaggttgtg acaataattt gtcacaacct cttttttaaa
    88921 atatctattt tgtttgattg ttcattgcgt cttctgcagc catttgcgct tcaatatctg
    88981 aaatactgta gacattttcg cttgctacac cgacttcttt tggttccatg tcacgataac
    89041 gttgcatacc agtaccagct gggatgatct tacctataat aacattttct ttcaaaccaa
    89101 gaagaggatc tttcttaccg cggatcgcag catccgtcaa gacacgagtt gtttcttgga
    89161 atgatgcagc agataagaaa ctatttgttt ctaatgatgc ttttgtgata cctagtaaga
    89221 caggtcgaga agttgcagga acgcctcctg agactagcgt attgtagttt tgatctttaa
    89281 agtctgcgat gtctaataat gtacctggta agatatctgt atcacctgga tccattacac
    89341 gaactttacg cagcatttga cgaaccatta cttcgatatg cttgtcgccg atttctaccc
    89401 cttgcatacg gtaaacacgt tgtacttcac gaagcaagta gttttcaaca gataatacat
    89461 cgcgaacttg caacaattgt tttggatcga ttgatccttc tgtcaatggt gcaccacggt
    89521 ggatcatatc gccttctgct actttcatac gtgctgtata aggaacagta tacgtacgtg
    89581 tatctgtttt tcctttgatt gttacttctt tggtacgtgt tgcaggatct tctgagatat
    89641 cgatgacatc ccctgttact tctgtgatca ctgcttgccc tttcggatta cgtgcttcaa
    89701 agatttcttg gacacgagga agaccttgag tgatatcgtc tccggcaacc ccacctgtat
    89761 ggaatgtacg catcgtcaac tgagtaccag gttcaccgat tgattgagcg gcgatcgtac
    89821 caactgcttc tccgacttca acgtcagagc cagttgcaag gttgcgtccg taacaatgtt
    89881 tgcagacacc atgttttgta ttacatgtga agacagaacg gattgtcact gtttcgacac
    89941 ctgcatcaac gatttgtttt gcgatgtctt cggaaatcaa ttggtttcct gcaatgatca
    90001 attcatttgt ttcaggatga cgtacttctt tacgggtgta acgtcccact aaacgatctt
    90061 ctaatgattc gatgatttca tttccctcgc ggatggcttg gatttcaaga cctcggtcag
    90121 taccgcaatc ttcttcacgg atgattacat cttgggccac gtcaaccaga cgacgagtca
    90181 agtaacctga atcggcagtc ttcaaggctg tatcggtcat ccctttacga gccccgtgag
    90241 ttgagataaa catttccaag acggatagtc cttcacggaa gttcgaaatg attggcaatt
    90301 ccatgattcg accattagga gcggccatca aaccacgcat tccggcaagc tgtgtaaagt
    90361 tggaaatgtt accacgagct ccagaatcag acatcatgaa gattggattt ttcgcttcca
    90421 aaccttccat cagtttttgt tggatgctgt cttttgcagc attccaaaca gcaatgacac
    90481 gttcataacg ttcgtcatct gtgatcagac cacgacggaa ttgttttgta atagtttcaa
    90541 cttgtttatg ggcattttca atgatttctt gtttttcatt cagtacactg atgtcagcga
    90601 tccctactgt gataccggca tgtgtcgaat gtttgtaccc taagtctttc atacggtcaa
    90661 gcatcttaga agtttctgtt actttgaatc gtttgaagac ttctgcgatg atgtttccta
    90721 agtttttctt cttgaacggt aatactaatt cttgctcttt gatatgtgca ggaatatcag
    90781 taccagcttc aacaaagtat ttgtccggtg tttggacggt caagttgaag tctgttggtt
    90841 cattcagata agggaattca ggaggcatga tctcgttgaa gatgatctta ccaactgttg
    90901 tgatcatcgt acgttctttt tgccattcag taaatggttt ttcacctaat gagttagggt
    90961 tcacaccgat acgtgaatgt aaatgaacat atccgttgcg ccatgcgata acggcttcgt
    91021 tttgatctct gaagaccatt ccttcgcctt cgcgtccttc ttcttccatt gtcaagtagt
    91081 agttacctag aaccatatct tgagaaggag taacaactgg tttaccatct ttagggttca
    91141 agatgttttg agcagctaac atcaacatac gtgcttctgc ttgtgcttct tcattcaatg
    91201 gaacgtggac agccatttgg tctccatcga aatcggcatt ataagcttca catacaagtg
    91261 gatgcaaacg gattgcgcgt ccttgtacta aaactggttc gaatgcttgg ataccaagtc
    91321 ggtgaagcgt aggtgcccgg ttcagcaata ctgggtgttc cttgattacg tcttctaaaa
    91381 catcccatac ttcgtcttct tgacgttcga ttttacgttt cgcatttttg atgtttgaag
    91441 ctagttcgcg ttgaacaagc tcacgcatca cgaatggttt gaataattca atggccattt
    91501 cttttggaag tccacattgg tacatcttca agaaaggtcc aacaacgata acggaacgac
    91561 ctgagtagtc gacacgttta cctagcaagt tttgacggaa acgaccttgt ttccctttca
    91621 acatatgaga aagagatttc aatgggcggt tacctggtcc agtaactgga cgtccgcgac
    91681 gaccgttatc gatcaatgca tctactgctt cttgcagcat acgtttttca ttttgaacga
    91741 tgattccagg tgcattcaag tctaacaaac gtttcaaacg gttattacgg ttgattacac
    91801 gacggtaaag atcattcaag tcacttgttg caaaacgtcc accttctaat tgaaccattg
    91861 ggcgtaaatc tggtggaata acagggataa cgtccataac catccagctt ggttgatttc
    91921 ctgaagcgcg gaatgcttct aaaatatcca aacggcggat tgcacgtgta cgtttttgtc
    91981 cttgtgcaga tttcaattct tctttcaatt cggctgcttc tgcatctaga tcaacattat
    92041 caagtaattg tttaatcgct tctgcaccca tagcagcttg gaattcttgt ccatattgtt
    92101 cacgtttttc gcgatattcg cgttctgtca acaattgttt tttctctaaa ttcgtatttc
    92161 ctggttcgat gactacatat gaagcaaaat aaatgatttc ttccaaagcg cgtgggctca
    92221 tgtctaatac aagacccata cgtgaaggaa tccctttaaa gtaccagata tgtgaaacag
    92281 gagctgctaa ttcaatatgt cccatgcgtt cacggcgaac tttcgaacga gtaacttcca
    92341 ctccgcatcg atcacaaacg attcctttat aacggatacg tttgtatttt ccgcaggcac
    92401 attcccagtc ttttgtagga ccaaaaatcc gctcacagaa caacccttcg cgttcaggtt
    92461 ttaaggtacg atagttaatc gtctcaggtt tttttacttc accgtaagac cagcttctga
    92521 ttttttcggg agaagccaaa cctatttgca tactttcgaa tttatttaca tcgatcaaaa
    92581 ggggttccct ccatttcatt taatggcaaa ccgcaagacg gctgatcttc gaccgccttg
    92641 cagctcatag accggattag tctaaattat cttctgcggt ttcaaagttt tggatgacat
    92701 cgtctttttc atcttccact tgttcagcag ctttcttttc taattctttg gcagtttgct
    92761 gttcggcaaa ttttgtcaaa gcatcaacag tgatcaaatc gtcgtcttca tcgtccatgt
    92821 cgcgaagttc gatctctgtt tcttcgatat ccaagacacg catgtccaga cctagtgatt
    92881 gcaattcttt caccaatacg cggaatgatt ccggtacacc tggttttgga attggttcac
    92941 ccttgacgat tgcttcgtat gttttcacac gtccgactac gtcatctgat ttgtatgtca
    93001 agatttcttg taaagtataa gccgcaccgt aagcttccag tgcccatact tccatttcac
    93061 caaaacgttg tccaccaaat tgagctttac ctcccaatgg ttgttgtgta accaatgagt
    93121 aaggtccgat tgaacgtgca tgcaatttgt catcgaccat gtgagcaagt ttgatcatgt
    93181 acatcacacc gacagacaca cgtccatcaa atggttcacc tgtacgtccg tcgtacagaa
    93241 cagttttcgc atcgctggcc ataccggctt cacgaactgt ttcccatacg tcttcatcac
    93301 ttgcaccatc aaatactggc gttgctacgt ggatacctaa ctgacgtgca gccataccca
    93361 agtgtaattc caatacttgc ccgatgttca tacgtgaagg cacccctaaa ggattcagca
    93421 tgatatcgat tggtgttcca tcaggtagga atggcatatc ttcttccggc ataatacggg
    93481 atacaacccc tttatttccg tgacgaccgg ccattttatc cccttcatgg attttacgtt
    93541 tttgaacgat ataaacacga actaacatgt ttacgcctgg tgacaattca tctccagctt
    93601 cacgagtaaa gattttcaca tcgtgaacga taccgccgcc gccatgtggt acacgtaatg
    93661 atgtatcgcg gacttcacga gctttttcgc caaagatcgc atgcaataga cgttcttctg
    93721 cagataattc tgttacccct tttggcgtga ctttccctac aagcaaatcg ccatcttgga
    93781 cttctgcacc aatacggatg atacccattt cgtctaaatc ttttaatgcg tcttccccga
    93841 cattagggat ttcgcgtgtg atttcttcag gtcctaattt tgtatcgcgg gcttctgatt
    93901 catattcttc aatatggata gaagtgtata cgtcatcttt taccaaacga cggctcatga
    93961 tgatcgcatc ttcatagttg tacccttccc aagtcatgaa accaactaaa acgttttggc
    94021 ctagagccat ttcgccttgt tccatagatg gtccgtctgc cagagtatcc cctttttcga
    94081 ctttctcacc caaatgaacg attggacgtt ggttgtagct tgttccggag tttgaacgac
    94141 ggaattttgt tacatcgtat ttatctaatg caccgttgtc gcggcgtacg cggatttcag
    94201 aagcatcaac gtattcaacg acaccgtcat gtttacataa caaagcagct cctgagtcat
    94261 gcgctgattt gtattccata ccagtaccaa cccatggtgc ttgaggattg atcaacggca
    94321 ctgcttgacg ctgcatgttg gcacccatca aggcacggtt ggagtcatcg ttttccaaga
    94381 aaggaataca tgctgtcgca acggcaacta cttgtttagg tgatacgtcc atgtagtcta
    94441 ctttatcaat agatacttct aagttttcac tttgagcacg agccataaca acgtcttgag
    94501 caaatgttcc atcttcattc aatgggctgt ttgcttgggc tacgatgtaa tggtcttcga
    94561 tatcagctgt caagtagtcg atttggtcag taacacgacc tgtttcacgg tctacacgac
    94621 gataaggtgt ttcgataaat ccgaatttat ttactttcgc ataactggac aaactattga
    94681 tcaacccgat gtttgggcct tcaggagttt cgatcggaca catacggcca tagtgggagt
    94741 agtgaacgtc acgaacttca taaccggcgc ggtcacgagt caatccgcca ggtcctaagg
    94801 ctgaaagacg acgtttgtgt gtcaattcgc caagagggtt tgtttgatcc atgaactgtg
    94861 acaactgaga agaaccaaag aattctttga tacttgccac aactggacgg atattgatca
    94921 attgttgagg tgtcaatgtt tcagtatctt ggatcgacat tctttcacga accacacgtt
    94981 ccatacgtgc tagcccgata cggaattggt tttgtaaaag ttcaccgact gaacggatac
    95041 gacgatttcc taagtggtcg atatcatcga cattgccgat accttccatc aagttcaaga
    95101 aatagctcat tgaagcaatg atgtcggctg gacgaaccgt ttttacagct gcttctggat
    95161 agccgtttcc gatcacgttt acttcacgtt cagggtctct tggtgaaaat actttgatga
    95221 cttggacagt cattggatct gtgaccacac cgtcttctga tggatagtaa gtcactgaat
    95281 ttaggccatt atcaatgaaa ggagctagtg tttccatgac ttggtgagtc agaactgttc
    95341 ctttttcaac gatgatctcg cctgtttctg gatcaactaa tgtttcagct aatgtcagat
    95401 tcaatagacg tgttttcaaa tctaattttt tgtttacttt gtaacgacca acgtttgcta
    95461 agtcgtaacg ttttggatcg aagaaacgag cattcagcaa gttacgtgag ctgtctgctg
    95521 tttttggttc gcctggacgc aaacgttcgt aaacgtcttt caaaccttct tctgttcttg
    95581 agtcgcttgc gtttttatgc aagtcttttt cgactgtatt gcgtaatgtt tcgctgtcgc
    95641 cgaagatttc aaagatcgta tcatcggaac caaatcctaa cgcacgaact aatacggtta
    95701 aaggaatctt acgtgtacgg tcgatacgta cataagagat gtcttttgca tcagtttcca
    95761 tttctagcca agctccacgg ttagggataa cagtagaacc gaatccttct tttccgtttt
    95821 tgtcgacttt tccatggaaa tagacacctg gtgaacggac taactgagaa acgattactc
    95881 gctctgcccc gttgatgatg aatgttcctt gttctgtcat taatgggaaa tcaccgaaga
    95941 atacttcttg tgctttgatt tcgccagtct cgcggtttgt caaacgcaat gttacatgta
    96001 atggtgcaga gtagtttgca tcatgcgcac gagcttctgc tactgtatac tttggttctt
    96061 tcaattcata atctacaaat tccaaagata gattgccatt gaagtcatcg attggcaaaa
    96121 tgtcttcaaa catttctcta agtccctcat ctaagaacca ttggtaagag tctgtttgaa
    96181 tttcgatcaa atttggtaat tccaacactt cactgattct tgcgaaactt ctacgttcgc
    96241 gatgttttcc gtattttact acgtgtccag ccaagctctt cacccctcta aaatgtcatt
    96301 caaaaagact acccgatcaa ttgttacaat aatatttcga atattatttt taggtaacaa
    96361 cagacatttt ttgcggcttt taggcaaaaa aaaaccaaaa atagaacatt ctcttgaaac
    96421 cttacttcgt gagcttctac ttttgtttcc ttatattaaa gccgaaacgg acaatatttc
    96481 gtttctgcct tttcttcatc agatagtttt tgcaacttca tatactacac ttattttcta
    96541 taaaagtcaa cacttcctgg cgtttcttct gctttttcgc aacattttct taatgttttc
    96601 aattttatgt tttcaattat ctgacaattc ttaattgaca gaccttttta tctcggttat
    96661 actttagaaa attcattttg tggaggaact tctatgcgaa ccaacatcaa ccaaatcgca
    96721 ccaacacaac tgaataactt ttactttagc tactttagat aggtttgtat tcatcatgat
    96781 ggatacaaac gttaaacgac agtttgtatc tatgatggct aaagaacttt gtattgcagc
    96841 aaaaagccac gtagacaaaa tgctaagtgg ctgagcagtg aaaatacaaa gtaaaagtat
    96901 caagcattct actttttcaa tttattttcc gacttttcaa tccatttgga cattttgtct
    96961 gaatggattt tttgtttccc aaaattaagg aggaaaaaga aatgaaaaaa aatataatca
    97021 tcggattagg cgctgccctg ctactagctt taggaggttg cgcacaaaaa gacaattccg
    97081 cagaggcatc agatggacaa aaaacaattg gcgtattgca acttgtacaa cataactcgt
    97141 tagatgctgc ctataaagga ttcaaagaag gattagcaga agaagggtat aaagaaggcg
    97201 ataatctaac aatcgattat caaaatgccc aaaacaatca agacaacctg aaaagtatga
    97261 gtgagaaact cgtcaaagaa gatcctgatt tgctacttgg aatcgccact ccagcagcac
    97321 aatctttatt aaatgaaaca accactatcc cgatgactgt cacagcggtc acagacttgg
    97381 aacaagccca tttagtcaca tccaatgaaa aacctggcgg caatgtgact ggcacgacag
    97441 atatggtgcc aatcgaaaaa caaatcggct tactgttaaa tatcgtgcca gacgccaaaa
    97501 caatcggcat catgtataac aacggtgaag caaactctaa gatccaagct gatttggcag
    97561 aaaaagaatt gaaaaaagcg ggcgtcaaag tcaaagtact gacagcaaat tccacaaatg
    97621 atgtccaaca agtgacgaaa agtctagcta aagatgtaga tggaatctat attcctactg
    97681 ataacacgtt cgcaagtgcg gcaagtgttg tcggtgaagt cgcaaaagaa acaaaaacac
    97741 ctgtcgttgc tggcgcagtt gatcaagtca aagacggcgg tctagcaaca gtaggaatcg
    97801 actacgaaag cttgggcaaa caaacaggga tcatggcagc aaaaatctta gacggcaaga
    97861 atccaagtga acttcctgtc gaaacagcga atgatttgga actgtatgtc aataaagaca
    97921 tggccaaagc attaggcatc aatccagaca gcatcaaaga agctgaataa aacacaggag
    97981 gattctcatg acaaatttgc tctctctttt cttatcatct gcatcgcaag gggtcttatg
    98041 ggccctactt gcgattggtg tatacgtcac tttccgtatc ttggacattg ccgacttgac
    98101 tgctgaagga agctttcctt taggtgcagg gatcgcggca gtaagtatta caaatggcta
    98161 tcatccattg acagcttgtc ttctaggctt tttagggggt gcggcagcag ggcttgtttc
    98221 cggactgctt cacacaaaat tgaaaattcc cgcccttctt gcagggatca tcaccatgac
    98281 tggtttatat tctgtcacat cccgtgtgat gggtgcgccg aacatctctt tattgggtca
    98341 gccaacgatc tttcattggg tcgagtcatt cggcataaca aaagacaacg ctgtactgat
    98401 cgtcggtctg ctttttgctt tgatcgttgt atgtttactt gttttgttct tacgtacaga
    98461 aacaggactt gctattcgtg caactggcga taatctggca atgagcgaag caaacgggat
    98521 caacacagat aatatgaaga tcatcggtta tatgatttct aatggatgca ttgctctttc
    98581 tggctcctta cttgcgcaaa acaacggctt tgctgattta aattctggta ttggaacgat
    98641 cgtaattgga cttgcttcta ttatcatcgc agaagttttg ttacgtaacc agccactatt
    98701 tctccgtctc ttgactgtcg ttttaggtgc ggtcatttat cgttttattt tagcgttagt
    98761 cttcgaactg aatgttgaac caagtgattc gaaacttgct tctgctttcg tgctagtgat
    98821 ctgtctttct ttcccgcaga tccagcaaaa attccattta cctcaaaaaa agaaaggcgg
    98881 tagtgtcaaa tgaatgacgt cttaacattg gaaaatctcc atcatacctt tgaaaaagga
    98941 acgatcaacg aaaatcatgt cctgaaaggc attaatcttt ccttagatcc cggcgacttc
    99001 gtgacgatca tcggtggaaa tggggctggt aaatctactt tgctgaacag catcgccggt
    99061 acattttctg tcgatcaggg tcaaatttta ttgaatggaa aaaatatcac gaaaaaatct
    99121 gttgtcgaac gttcgaaatc catcagtcgc gtattccaag atcctaaact agggacagcc
    99181 gttcgtttaa cggtagaaga aaatcttgct cttgctatga aacgaggaaa aaaacgcggc
    99241 ttcttccgtg gtgtcaaacc acaagaccga acatttttca aagaccagct ggttcggcta
    99301 aatttggggt tggaaaatcg tttatcctca gaaatcggtt tgctgtctgg aggacaacgt
    99361 caagctatta cgttattgat ggccacatta cagcgtccag aactgatctt attagatgaa
    99421 cacactgcag cgcttgaccc tgctacttcc aaaacggtga tggaattgac agaaaagctg
    99481 atcactgagc agaatctcac tgcttttatg gtcactcatg acatggaaga cgcgatccgc
    99541 tatgggagtc gactgatcat gctgcatcaa ggaaggatcg tcgtagatat ccagcaagag
    99601 gaaaaacagc agctcacagt gccccaatta ttagcgttgt tcaaacaaaa cagcggcacg
    99661 gcattaaaag acgatcaagt acttttatct tcataatcag aaagaggatg ggacaaaaaa
    99721 tgaacgccca ccctcttctt ttttctcttt ccttctttcg tttttgcttt atgtatcaac
    99781 cgttgtttct tcgaaaacta ttttgttctc tccttctttc tgatagaatg gatgggaaag
    99841 gagcttgatg ccatgacaac gaaagacaag gtacttcaat tattgaaaaa gacaccagat
    99901 tttctttccg gagaaaagtt ggcacagcaa ctggaagttt cccggacaag tatttggaaa
    99961 gccatcaaag aattggaaaa ggcaggctat cgttttgagc acgggcctac agggtatcgt
   100021 tacctgccct ctgacgtact agatgcaaaa gaaatccagc aagagctacg gtcgtttatt
   100081 cctgatttga aagtacaaac gatgttgact tctgaatcta cgatgaaaga tgccaaactg
   100141 gcagcagctc aaggagattc tgtttcgaag ttatttgttg ctgatacaca agaacaagct
   100201 cgtggacgtt ttggacggcc ttttttcgct gaacctggac gaggaatcta catgagtctc
   100261 ttgctccatc cagacaaacg gtttgatgaa ttgcctcaat atacgatcat cgcagccagt
   100321 gcctgtgtga aagccattga atctgtaacc ggtcgttctg cttcgatcaa atgggtcaat
   100381 gatatctaca tggatggaaa aaaagtctgt gggattttat ctgaagcagt cagtgatatg
   100441 gaaagcggca ggatcagtca tatcatcatt gggatcgggc ttaatttttc tgttcctcaa
   100501 aatcattttc cagctgatct ccaagaaaaa gccatctctg tctttcccga cggacaagct
   100561 agtgtcacaa ggaatcagct aatcagcaaa atctggcaag aattgttcac ttatctttct
   100621 cacccagaaa aagcgttgga cttctataaa gaaaaatcat tcgtattggg aaaaaccgtg
   100681 tcgttcaatc aaaaaggaac gacttatgtc ggtcttgcaa aagaaatcgg tgatcatggc
   100741 gaactgatcg tccaaacaaa tgaacagaag atgagtttgt cttctggcga aatcagtctc
   100801 acatctatcc gtacgcaata attatcagat ttcacaaaag gacacctgat ctcatacagt
   100861 gtcctttttt ctgaattctc ttcaaaagac tctccttatt ctatcagctg acagtttctc
   100921 tatcctctag aaaaaggtat tctaaaaata tctataaagc atggtacact ttctttaaat
   100981 gaatcaatgc aaaaaacaag agagtcatca gtttacacga tcaaaagaga tagcaggccg
   101041 cttccttttt caatcttata gatagaccat gggtaacgat aaaaacaaaa aagaacttgc
   101101 gacttatttt gccgtaagtt cttttttagc tagtgcctta atctcttaat cccaacaaac
   101161 gtctcgcata gatcacctga ccagagtgca tagcagcatc atcaataata gaaacgagac
   101221 gcattcctcg tgtgactggt ggtgtccagt tctcgtcaat tacttcatct agctcggaag
   101281 gttccagcct tcttaagtaa gaaatagcaa aatcagcagc tcctcgcaag tatcctagca
   101341 gatcttctat ttgattagct tggatctgct ttgcttgttc cagactatgc ttccaatctt
   101401 gttcgttatc tgctatcgtc atcggaaacc ggctttccca gtcttgacta tgccaaattg
   101461 gagaagttcc tgctaaatca gcaatctgga aatctaattc tcgagcggta tgccaagcca
   101521 gccaagtcat tgatttgatc tgcggggctc tatcttccac tggaaaacga ttggcctcct
   101581 caatagagac gccttcaaac aaacgttcaa accgatcgta tgcccgatcc acactctcgc
   101641 atagcatatc taaataatcc atttattttc ctccttttta tttatcctac ttactttttc
   101701 ctaattctag gatacctact tatatgttac tacacaccct tattttttac actttaacag
   101761 tcaccatcat caatagtttg gagattgaaa gaaaaagata gtgtcgaact atcaattgaa
   101821 caagaagcaa caatatgaac gtttcattaa tattctttaa ataaacaatg atttttcaaa
   101881 cgaacagttt aagactagga gaaaaagagt ataataggaa aatgtttgaa aggaaaggaa
   101941 ggggaaaaat gaaaaaaagg gcaagtttac tagtcctagt tgctttgttg ttcaatatct
   102001 tttcgtatgg tgtggccgtt tcagcggaaa catacattcc taaagaccct gggaatattt
   102061 ataatgatct aactggtaac tatggcttgt taggaattgc tagtcaattc cacgtatttg
   102121 ctaaaaataa gacaactgtg aatgcacata cagacggaaa tatagcaaca catgaacttg
   102181 atgcaaaaaa taattttggt acagagcttc atgaaggttt attgaaccaa gaaataaatt
   102241 atatacaaaa aactgattct ttcgctaatt cttcaggcat acctacaggt agcacaagaa
   102301 tgaataaatt tgtcgttggc agtaacgtgg atgtagcact tcaagatggt catcctacag
   102361 tcaatggatc caggcttgat cacttaactc cagatgattt ttataaagat cgtgctgggc
   102421 atgaatatat tgatttcgag caggaatttg ctaaattgaa tgtagcagca aatgatcttg
   102481 caacgatcac tccagctaaa acatatactg ctgcagattt tccagacatg aacaatcgga
   102541 caatcgattt aactgattta tcagataccg ggtttttatt ggtaaatatc gatgcagaag
   102601 tgttaacgat gaatacgcca cttcaaatca ttaatccaaa tgatcaagta gttgtattta
   102661 atgtcatcaa cagttcttct gcattgaacg tacagtcacc aatcaaatac aatgatcgtt
   102721 caaatcatga aacagaagat ttttcggatg cgaatatctc ttggaatttt ggaaatgaga
   102781 tgactgattt gacaatcagt gctccttttc aaggaacaat ccttgcgcct aatgctacta
   102841 tccgcattac tcaaaaccaa gacggaacga ttataggaac aaatgtgatt ttagatgcag
   102901 ctaccaatcg ttgggatcct aacgaaatat ttatcagcga caatggtaca gatacgacag
   102961 acacaagcga cagtacagat acatctacca caagtgatag ctcagattca tca
//
LOCUS       DAXQKX010000003        77858 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.003, whole genome shotgun sequence.
ACCESSION   DAXQKX010000003 DAXQKX010000000
VERSION     DAXQKX010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 77858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 77858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77858
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.003"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            591..1280
                     /locus_tag="ACF3MF_000220"
     CDS             591..1280
                     /locus_tag="ACF3MF_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFE3926253.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1267..2475
                     /locus_tag="ACF3MF_000221"
     CDS             1267..2475
                     /locus_tag="ACF3MF_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFE3926254.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2769..4040
                     /gene="serS"
                     /locus_tag="ACF3MF_000222"
     CDS             2769..4040
                     /gene="serS"
                     /locus_tag="ACF3MF_000222"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HFE3926255.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="ACF3MF_000223"
     CDS             complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="ACF3MF_000223"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HFE3926256.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6578..7273)
                     /locus_tag="ACF3MF_000224"
     CDS             complement(6578..7273)
                     /locus_tag="ACF3MF_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HFE3926257.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="ACF3MF_000225"
     CDS             complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="ACF3MF_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HFE3926258.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8472..8663)
                     /locus_tag="ACF3MF_000226"
     CDS             complement(8472..8663)
                     /locus_tag="ACF3MF_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HFE3926259.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8684..9574)
                     /locus_tag="ACF3MF_000227"
     CDS             complement(8684..9574)
                     /locus_tag="ACF3MF_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HFE3926260.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9561..10328)
                     /locus_tag="ACF3MF_000228"
     CDS             complement(9561..10328)
                     /locus_tag="ACF3MF_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFE3926261.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="ACF3MF_000229"
     CDS             complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="ACF3MF_000229"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HFE3926262.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="ACF3MF_000230"
     CDS             complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="ACF3MF_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HFE3926263.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="ACF3MF_000231"
     CDS             complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="ACF3MF_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HFE3926264.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14899..15282
                     /locus_tag="ACF3MF_000232"
     CDS             14899..15282
                     /locus_tag="ACF3MF_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926265.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15450..16208)
                     /gene="jag"
                     /locus_tag="ACF3MF_000233"
     CDS             complement(15450..16208)
                     /gene="jag"
                     /locus_tag="ACF3MF_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HFE3926266.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16226..17044)
                     /locus_tag="ACF3MF_000234"
     CDS             complement(16226..17044)
                     /locus_tag="ACF3MF_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0032977 - membrane insertase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YidC/Oxa1 family membrane protein insertase"
                     /protein_id="HFE3926267.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="ACF3MF_000235"
     CDS             complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="ACF3MF_000235"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HFE3926268.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="ACF3MF_000236"
     CDS             complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="ACF3MF_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HFE3926269.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18172..19506
                     /gene="dnaA"
                     /locus_tag="ACF3MF_000237"
     CDS             18172..19506
                     /gene="dnaA"
                     /locus_tag="ACF3MF_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HFE3926270.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19704..20834
                     /gene="dnaN"
                     /locus_tag="ACF3MF_000238"
     CDS             19704..20834
                     /gene="dnaN"
                     /locus_tag="ACF3MF_000238"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HFE3926271.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21063..21305
                     /gene="yaaA"
                     /locus_tag="ACF3MF_000239"
     CDS             21063..21305
                     /gene="yaaA"
                     /locus_tag="ACF3MF_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HFE3926272.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21292..22416
                     /gene="recF"
                     /locus_tag="ACF3MF_000240"
     CDS             21292..22416
                     /gene="recF"
                     /locus_tag="ACF3MF_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HFE3926273.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQTRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22413..24359
                     /gene="gyrB"
                     /locus_tag="ACF3MF_000241"
     CDS             22413..24359
                     /gene="gyrB"
                     /locus_tag="ACF3MF_000241"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HFE3926274.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24379..26850
                     /gene="gyrA"
                     /locus_tag="ACF3MF_000242"
     CDS             24379..26850
                     /gene="gyrA"
                     /locus_tag="ACF3MF_000242"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HFE3926275.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27086..27385
                     /gene="rpsF"
                     /locus_tag="ACF3MF_000243"
     CDS             27086..27385
                     /gene="rpsF"
                     /locus_tag="ACF3MF_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HFE3926276.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27435..27947
                     /gene="ssb"
                     /locus_tag="ACF3MF_000244"
     CDS             27435..27947
                     /gene="ssb"
                     /locus_tag="ACF3MF_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFE3926277.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27973..28209
                     /gene="rpsR"
                     /locus_tag="ACF3MF_000245"
     CDS             27973..28209
                     /gene="rpsR"
                     /locus_tag="ACF3MF_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HFE3926278.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28352..30325
                     /locus_tag="ACF3MF_000246"
     CDS             28352..30325
                     /locus_tag="ACF3MF_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HFE3926279.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30331..30783
                     /gene="rplI"
                     /locus_tag="ACF3MF_000247"
     CDS             30331..30783
                     /gene="rplI"
                     /locus_tag="ACF3MF_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HFE3926280.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31057..32424
                     /gene="dnaB"
                     /locus_tag="ACF3MF_000248"
     CDS             31057..32424
                     /gene="dnaB"
                     /locus_tag="ACF3MF_000248"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HFE3926281.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33204..34496
                     /locus_tag="ACF3MF_000249"
     CDS             33204..34496
                     /locus_tag="ACF3MF_000249"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HFE3926282.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
     gene            35232..36095
                     /locus_tag="ACF3MF_000250"
     CDS             35232..36095
                     /locus_tag="ACF3MF_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFE3926283.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(36224..37846)
                     /locus_tag="ACF3MF_000251"
     CDS             complement(36224..37846)
                     /locus_tag="ACF3MF_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFE3926284.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            38095..38616
                     /locus_tag="ACF3MF_000252"
     CDS             38095..38616
                     /locus_tag="ACF3MF_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HFE3926285.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(38802..40532)
                     /gene="spxB"
                     /locus_tag="ACF3MF_000253"
     CDS             complement(38802..40532)
                     /gene="spxB"
                     /locus_tag="ACF3MF_000253"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HFE3926286.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            40697..41515
                     /locus_tag="ACF3MF_000254"
     CDS             40697..41515
                     /locus_tag="ACF3MF_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HFE3926287.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(41618..41815)
                     /locus_tag="ACF3MF_000255"
     CDS             complement(41618..41815)
                     /locus_tag="ACF3MF_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926288.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            41984..42562
                     /locus_tag="ACF3MF_000256"
     CDS             41984..42562
                     /locus_tag="ACF3MF_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HFE3926289.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            42657..42794
                     /locus_tag="ACF3MF_000257"
     CDS             42657..42794
                     /locus_tag="ACF3MF_000257"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926290.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(43607..44110)
                     /locus_tag="ACF3MF_000258"
     CDS             complement(43607..44110)
                     /locus_tag="ACF3MF_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFE3926291.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            44469..45494
                     /locus_tag="ACF3MF_000259"
     CDS             44469..45494
                     /locus_tag="ACF3MF_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFE3926292.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            45841..46719
                     /locus_tag="ACF3MF_000260"
     CDS             45841..46719
                     /locus_tag="ACF3MF_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase domain-containing protein"
                     /protein_id="HFE3926293.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            47195..47311
                     /locus_tag="ACF3MF_000261"
     CDS             47195..47311
                     /locus_tag="ACF3MF_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HFE3926294.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            48239..48577
                     /locus_tag="ACF3MF_000262"
     CDS             48239..48577
                     /locus_tag="ACF3MF_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926295.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            48671..48901
                     /locus_tag="ACF3MF_000263"
     CDS             48671..48901
                     /locus_tag="ACF3MF_000263"
                     /inference="COORDINATES: protein motif:HMM:NF042636.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6568 family protein"
                     /protein_id="HFE3926296.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            49301..49672
                     /locus_tag="ACF3MF_000264"
     CDS             49301..49672
                     /locus_tag="ACF3MF_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HFE3926297.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(49946..50638)
                     /locus_tag="ACF3MF_000265"
     CDS             complement(49946..50638)
                     /locus_tag="ACF3MF_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFE3926298.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(50641..51426)
                     /locus_tag="ACF3MF_000266"
     CDS             complement(50641..51426)
                     /locus_tag="ACF3MF_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFE3926299.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            51663..53063
                     /gene="lacG"
                     /locus_tag="ACF3MF_000267"
     CDS             51663..53063
                     /gene="lacG"
                     /locus_tag="ACF3MF_000267"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HFE3926300.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            53088..53405
                     /locus_tag="ACF3MF_000268"
     CDS             53088..53405
                     /locus_tag="ACF3MF_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFE3926301.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            53418..55091
                     /locus_tag="ACF3MF_000269"
     CDS             53418..55091
                     /locus_tag="ACF3MF_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HFE3926302.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            55105..56736
                     /locus_tag="ACF3MF_000270"
     CDS             55105..56736
                     /locus_tag="ACF3MF_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinogalactan endo-beta-1,4-galactanase"
                     /protein_id="HFE3926303.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            57608..58798
                     /locus_tag="ACF3MF_000271"
     CDS             57608..58798
                     /locus_tag="ACF3MF_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISLgar5 family transposase"
                     /protein_id="HFE3926304.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHYYTPQTMSNITKSFTEEVTAFNGRELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILLDLQERG
                     LKNVLLFITDGLKGMVGAISRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKEVALEARGTFAEKWKTSYPKVVESILSNDHLLTFYDFPLAIRKSIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESMERFLVSSFDTYNQKFLGRSHKGFQQAEGELEQMLSQ
                     LIEN"
     gene            58932..61121
                     /locus_tag="ACF3MF_000272"
     CDS             58932..61121
                     /locus_tag="ACF3MF_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFE3926305.1"
                     /translation="MFISTLQIRNFRNYESEIFRFDNETNTIIGENDSGKTNALTALR
                     ILLDDSYYYSSKTLKESDFFHGIQNGWQGHWIIISATFEGISEEEFDNEICASISLNS
                     ESQTILEELISNADKGVGSISLFIRPNKAIRKQLFDISTELDSHQFNEFRNSIRLSDY
                     EFYYTSKSNLNFCINENYDKLVGRLNDNIASNPEEDDEALLGSRIDMSDIFKHISVVY
                     VDALRDVLREMKNNRNPVKRIMETIESKISSDNVESLKTIIQQLNETITSVPEIRKIG
                     ENINRQLNSIIGSVYSPNLLLSSTMSDDMGSLAKFLSMKPEQNIDLDLLGLGHLNMIY
                     LALKIVEFEACRSRELLNIMLIEEPEAHIHHHIQKTLFEGLNLQKNYTQILMTTHSVH
                     LAEVSEISRMNVLKSFNGKSIVMNPANNLNSFAKEKLKKNNLNLINAVERYLDVKRNG
                     LLFSKGVILVEGDAEEILIPQIVKKLFGINLDELGIGLINVGSTSFEYIASLFDDDRI
                     QRKCAIVTDLDEQAIPSEHRLYKSTAQEKGQARKEKLSSLFNENNWVNCFYANTTFEI
                     EFLDVNKENILTYVSPIIDDAFKDKKTITAYKEEIQSEQYLERNLAMLKLANHVGKGW
                     FAIELGEKIDFLIKIPKYILNAIAFACQEIVDLSIYKKILLHTIDLYEETTELSALSA
                     SLKTSDTADLNIAIISLLEYFGKDEDVVYLINQIENYTKILYAEVSK"
     gene            61118..62911
                     /locus_tag="ACF3MF_000273"
     CDS             61118..62911
                     /locus_tag="ACF3MF_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HFE3926306.1"
                     /translation="MTNIFEKIVNDLNLEQKDVVESEDNLYVNACPGSGKTRVLTRKI
                     AYQAIKHDGSLKRIIAITYTNRAAEEIKERLSLLSIDDDINIWVGTIHQFCLEFIIYP
                     FKMNLSRVSKGFTIIDDYTQRAYVSQINNMLNLNLKTYELNKIDLSLSHDFKINEVQY
                     TQVSEMYHTMLEKNKEIDFDMILLVAYKILTVNSNVARNIASNIRAIYVDEFQDTREL
                     QYNVIAKLLQNNPQIQSMFVGDIDQAIYGSLDGIAKSVEELEMLTSHTFQSKTLHGCY
                     RSNQRLVDFYSNFQSCPYEIESRGNNKNDRGFISYDCKVTKEDLPNIIKNIIKEKIES
                     GIHEKDICVLAPQHYPLFSLGEYLKKELPYCNFDAINISPIKVNNHSLFFKLAILYFT
                     ESGEKVRRRKLIANDILIILKNEFGIEVKDYFIDLDLLQLINSVKRMYSGDDNGVDLY
                     KFVTKHIFVNLNIDEKNYPSIFKHYLFFINEVEDRIKNNSLSSSVSSFKKMFKSRDGI
                     TLTTAHKVKGNEYDTVIAINLLNGKIPHWNEIFNVSDKGISSARKLLYVICSRAKNNL
                     FLFSEVGYFTSKGDLLYPTQLLDKIEFDYNI"
     gene            63111..63425
                     /locus_tag="ACF3MF_000274"
     CDS             63111..63425
                     /locus_tag="ACF3MF_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFE3926307.1"
                     /translation="MELKYVIPNMEKTFGQLEYAGEGNIEQRRINGRPTILSRSYNLY
                     STIQRADDIVVILPSEAGEKHFESDEKVKLINPHITAEGYKIGNRGFTNYIMHADDMV
                     KA"
     gene            63446..63823
                     /locus_tag="ACF3MF_000275"
     CDS             63446..63823
                     /locus_tag="ACF3MF_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFE3926308.1"
                     /translation="MRLAEGIVIEKDQTFGTLKFSALRREVRIQNEDGTVSEEIKERT
                     YDLKSKGQGRMIQVSIPASVPLKEFDYNAEVELINPVADTVATATFRGADVDWYVKAD
                     DLVLKGQTKPHQKYKKEASESEK"
     gene            63833..64606
                     /locus_tag="ACF3MF_000276"
     CDS             63833..64606
                     /locus_tag="ACF3MF_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926309.1"
                     /translation="MTNTPLILKEIPKDEAISFIRQYHYSKILPRLCKYFLGIFSEEK
                     LLGVVELGWGTQPLQTIRKLFPDSSLQTTDYLEIGKMCFLPEMNQTNYFGSQALSALI
                     KWLKEHTDCHFLYTLADGIEGKCGYVYQASNFFYCGYFKTSVYRDKQSWEKIHPRSAR
                     LLLEENARFEQVEKKHWLSQAFCEYKGIEKINGRMFRYLYPLTKEAKKLLGHTLYRRH
                     YYPKEKNLRFEKRIAYQKYEAISQPTFDKQARIYNTQLF"
     gene            64628..66031
                     /locus_tag="ACF3MF_000277"
     CDS             64628..66031
                     /locus_tag="ACF3MF_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HFE3926310.1"
                     /translation="MPLLHDRGERIKANDKHLVYHFVLISLLVVFLVVLLPFHWRALQ
                     SVNWQAVQLDTFFYQLHTPYFWSSILTALFVCGLISWLYYHYRIDSIKQLEHRQKLAR
                     MILENHWYEAEETQSEGFFKDLPSKKTKQRIRHFPKIYYRMKDGLIHIHVEITLGKYQ
                     DQLLHLENKLETGLYCELVEKTLKDSYVEYVLLYDTIGNRIGIEDVVAQDGRVKLMES
                     VYWEFDSLPHMLIAGGTGSGKSYFILTLIESLLHTNAKLYILDPKNADLADLGAVMNN
                     VYYRKEDMLACINQFYEDMIDRSETMKQHPNYKTGENYAYLGLSANFLIFDEYVAMMD
                     MLGRESTTVIHKLKQIVMLGRQAGFFLILACQRPDAKYFSDGIRDNFNFRVALGRMSE
                     MGFGMMFGSDTQKQFFLKPIKGRGYVDTGKSVISEFYTPLVPKRYDFLGEIGKVIQKK
                     QSEPVPHEVKGTGSDLL"
     gene            66213..67397
                     /gene="mobT"
                     /locus_tag="ACF3MF_000278"
     CDS             66213..67397
                     /gene="mobT"
                     /locus_tag="ACF3MF_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobT family relaxase"
                     /protein_id="HFE3926311.1"
                     /translation="MENEKIWIKELKEKRLAYGVSQNKLAVASHITRPYLSDIETGKA
                     VPTQQVKEDLLNALERFNPDNPLEMLFDYVRIRFPTNDVAQIIGEVLRLNMDYMLHED
                     FGYYSYPEHYRFGDIVVLVSHDVSKGVLLELKGKGCRQFENFLLAQHRSWYDFFQDCM
                     EHKGIFKRLDLAINDKTGILNIPDLAKKCKQEECISVFRSFKNYRSGELVHRDEKPYM
                     GNTLYIGSLKSEVYFCIYEKDYEQYVKNDVPLEDAEVKNRFEIRLKNDRATQAMKDLL
                     AHQQAEKTAFEIINRYIRFADKDDTKRRSDWKTNERWEWFIGKNRGALRLTTQPEPYS
                     FERTLNWLHHQVAPTLKIASILDVLNGTTIISTMIQEAKLTEKHEKLIEQQHLAMEDL
                     IT"
     gene            67394..67684
                     /locus_tag="ACF3MF_000279"
     CDS             67394..67684
                     /locus_tag="ACF3MF_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926312.1"
                     /translation="MSLLTKELKKLGFQCGIEFQAYIQNTGKYTSLIIEGKRQAGDTI
                     YTYDFYKVRFYNNYTNRVTVYGEHLTPFQLLRRVKSYIYYREKYLKERRTIT"
     gene            67681..67902
                     /locus_tag="ACF3MF_000280"
     CDS             67681..67902
                     /locus_tag="ACF3MF_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926313.1"
                     /translation="MNFGQNLYNWFLDNAQSLVLLAIVVIGLFLGFKREFSKLIGFLI
                     IALIAVGLVFNAAGVKDVLLNLFNRIIGA"
     gene            67944..68723
                     /locus_tag="ACF3MF_000281"
     CDS             67944..68723
                     /locus_tag="ACF3MF_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HFE3926314.1"
                     /translation="MKGFMNMFTNDQFKSLLIKTLERKSSSNYYEGGNEIVSKMKISE
                     VTLDETDDFTYYKGYKKGWNTLCTYLKIRVPFDDLDFFESHKDLITQTASSIYDKQGD
                     NVLVDTILVPLPENYEVINFSQLKISDVVSQAIEDAESFMSNGEYQRAFDRVHTAFHG
                     YLIEILKKYEITVPRDENLSKLYSRIQQLIEKEIQPTELADIVKTTIRSSNGMISSLN
                     EARNRHSLAHPNTNIIGKREAKLIIGISSTVTDYISGYLDK"
     gene            68784..69284
                     /locus_tag="ACF3MF_000282"
     CDS             68784..69284
                     /locus_tag="ACF3MF_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000425404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HFE3926315.1"
                     /translation="MEMKVYVANLGRYNEGELVGAWFTPPIDEEEMAERIGLNEDYEE
                     YAIHDFELPFDVDEYTPISEINRLCEAIQEIEGTPIYNELKEIQGMWFSSLEELLENK
                     EDIHCYSDCDSMEDVARYYVEETGQLGEVPSNLQNYIDYQSLGRDMEIEGNYLVTSHG
                     VFEYCQ"
     gene            69340..69978
                     /locus_tag="ACF3MF_000283"
     CDS             69340..69978
                     /locus_tag="ACF3MF_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6037 family protein"
                     /protein_id="HFE3926316.1"
                     /translation="MVNVFENLKLLKLDMKDKGWVIDSFYFRYKQQNYIVLVKLFEKE
                     EKVPEYALLKLEFLKENDFSDMLAVYANSVKLYTDTKTIREYFGIEYSSNLGDVLFQF
                     SQTLARFIPTEVSEKKNEDQKEAMCFSLSQSDSEDPRKKYCFSVRRNPLKGNGELGKR
                     SPFNDNKTRLYRPSLYERLGSDTNLSFRYSMNPDDEETDEGIIAKWTKNKIE"
     gene            70050..70445
                     /locus_tag="ACF3MF_000284"
     CDS             70050..70445
                     /locus_tag="ACF3MF_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFE3926317.1"
                     /translation="MKKIRSYTSIWSVEKVIYAINDLQLPFPITFTQMTWFIVSLFVV
                     ILFGSLPPLSLIDGALLKYLGIPIVLTGFMCQKTFDGKKPYGFLKSIITYALRPKVTY
                     AGKQIRLKKETMNESITIVRSEQLDGISD"
     gene            70429..72882
                     /locus_tag="ACF3MF_000285"
     CDS             70429..72882
                     /locus_tag="ACF3MF_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFE3926318.1"
                     /translation="MAYPIKYMEDNLVFNHDGEVFAYYELIPYNYSFLSSDEKIQVHD
                     NFCQLIAQNRDGKIHALQLATESSIRATQEQSKKEITGRLKEIAYEKIDEQTEALISM
                     IGDNQVDYRFFIGFKLYLNEQEVSVKNVGKEIQKAFAEFFHGVNHKLMGDFVSMPMAE
                     IERFSKMEQLLESKLSRRFQIRKLEKDDFGYIIEHLYGQTGVPFDDYDYHLPKRYEDK
                     KVLVKKYDILKPTRCLIEENQRYLRIEQEDTTTYVAYFTINSIVGELDFPNSEIFYYQ
                     QQQFTFPVDTSMNVEIVANKKALSTVRNKKKELKDLDSHAWESDNETSTNVVDALESV
                     DELESNLDQTKESMYKLSYVVRVSAKNLDELKQRCDEVKDFYDDLSIKLVRPFGDMLG
                     LHNEFIPSSKRYINDYIQYVTSDFLAGLGFGATQMIGENSGIYVGYNLDTGRNIYLQP
                     SLASQGIKGSVTNALASAFIGSLGGGKSFSNNMLVYYSVLFGGQATIVDPKAERGEWK
                     ETLPDIAHEINIVNLTSENDNKGLLDPYVILKLPKDSESLAIDILTFLTGISSRDSEK
                     FPVLRKAIRSVTQSKQRGLLLVIDELRKEDTPISNSIADHIESFVDYDFAHLLFSDGS
                     VTQSISLEKQLNIIQVADLVLPDSNSSFEEYTTMELLSVAMLIVISTFALDFIHSDRS
                     IFKIVDLDEAWSFLQVAQGKALSMRLVRAGRAMNAGVYFVTQNADDLLDEKMKNNIGL
                     KFAFRSTDLVEIKKTLEFFGVDKEDENNQKRLRELENGQCLVSDIYGRVGVMQFHPIF
                     EELLHAFDTRPPVRNEVEE"
     gene            72879..74906
                     /locus_tag="ACF3MF_000286"
     CDS             72879..74906
                     /locus_tag="ACF3MF_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HFE3926319.1"
                     /translation="MTQKQKKFLHYSWITLLCVGVILLLLGTLGNAVQATGLVDETID
                     TSNEYSKYGLNQYQLDYYVDNSWGWLPWNWSDGIGQSVMYGLYAITNFIWTISLYLSN
                     ATGYLVKEAYALDFISQTSQAIGENMQTIAGITPNGFSSSGFYVGFLLLFILIVGIYV
                     AYTGLVKRETTKVIRAVLNFVVVFILSASFIAYAPDYIAKINDFSKDVSTASLNIGTK
                     IVLPNTDSQGKDSVDMIRDSLFSVQVKQPWLLLQYGSTDVEALGEERVESLLSTSPDT
                     NNGEDRENVVIEEIEDHDNTYLTLPKTISRLGTVFFLFVFNIGISIFVFLLTGIMIFS
                     QVLFIIFAMFLPISFLLSMLPSFDGMGRHAITKLFNVIMTRAGITLIITVAFSISTML
                     YSLSASSPFFMIMFLQIVTFAGIYFKLGDLMSLFTLQSNDSQNMGRQVFRRPRQMMNR
                     QTRRFQRSMSKIFRGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQ
                     QGGIGQRLGEKTAHVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDF
                     KQSMADTKAQRKQQRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRK
                     RQQTVTPVLSQNTKRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            74903..75925
                     /locus_tag="ACF3MF_000287"
     CDS             74903..75925
                     /locus_tag="ACF3MF_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HFE3926320.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDDETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDLIFFHSTYNAGTYVTHVAIYLEGNRFYHAGDPIGYGDLSSRYWQDHLIGA
                     RRVIHN"
     gene            75942..76871
                     /locus_tag="ACF3MF_000288"
     CDS             75942..76871
                     /locus_tag="ACF3MF_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFE3926321.1"
                     /translation="MIIKIERKEKKEKPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQDNWKIVK"
     gene            77185..77232
                     /locus_tag="ACF3MF_000289"
                     /pseudo
     CDS             77185..77232
                     /locus_tag="ACF3MF_000289"
                     /inference="COORDINATES: protein motif:HMM:NF011335.0"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            77248..>77858
                     /locus_tag="ACF3MF_000290"
     CDS             77248..>77858
                     /locus_tag="ACF3MF_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFE3926322.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQE"
BASE COUNT        24718 a        13898 c        15385 g        23857 t
ORIGIN      
        1 ggagtgtttc ccgattcgtt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagtaattgt caactctttt ttaaaagttt tttcgatttc gtttttcgaa atcttccagc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcat
      241 ttccaacatg tcaacaactt attttttatt atttaataag ttattggtgt tcttttgaac
      301 aaataataat atatcaacat cacatgtgaa agtcaataag aaaatgctta tttatcaaca
      361 tttctagctt acatgatcat tggttagttc tggtcctttt tcgttcgtct ttataactcc
      421 gagagacgta aaatcctttt gttttcagtt taatgttcat gttcttgtct tattcacacc
      481 aactagatgt ctcaccttct aaaattttcc ttaacaaagt gctgctttta tctatttctg
      541 cttttttttg ctagaataat agtaacaata tgactctgga ggatttattt atgaaaattt
      601 tgattgctga cgatgataaa gaaatcgttg aattattaag tatctatgtt cacaatgagg
      661 ggtatgaagc agtaaaggct tatgatggga aagaagcatt atctaaaatc agaacaatcc
      721 ctgatattga attacttatt ttagatatca tgatgcctga gatggatggg atgcaagtag
      781 tgaaagagct acgaaaagaa tcccaaatac caatcattat gctgacagca aaaactactg
      841 atatggataa gatcaaagga ctggtcgctg gtgcagatga ttatgtgacc aagccattta
      901 atccgttaga agtaatggct agagtaaagt ctttattacg gcgtacaaaa atgcagattg
      961 ccccagatca gcctgatgta ttagaagtaa atgcattaat catcaataaa gactctcatg
     1021 aagttaaaac aatcgatggg aaagaaatcc agttaacagc tttggaattc ggtatcctct
     1081 acttgcttgc tagtcatcct aatcgagtat ttagcgcgga tgaaattttt gagcgtgttt
     1141 ggaaacaaga aagtattgtc tctgctaaaa ctgtcatggt tcacgttagt catttaagag
     1201 ataagattga agaagcaact ggtggtgaaa aagtcattca aaccgtttgg ggagtgggct
     1261 ataaaattga cgcaagatag taaacgagca actgaaaaac gccgtcggat caatttgact
     1321 tcaaaagaaa tcagcgaatt gttagcggaa ggaatcatca cgattatcct tttgcttcta
     1381 ttaaatgttt ctattctggt tgttatcagt tcggtgatca acagttcacc ttctttgacg
     1441 aatgcgattt gggattcaaa gaatattttt gcagaacgat tgaacactga tttgttctgg
     1501 aacggccgga attttattat tccctttttc tttctattag atattggtgt tttgtattgg
     1561 cgcttgattc gaagatatcg ccaaatgcaa ttgcggcata tcatcagcga acttcactac
     1621 atcgcaaacg gaaattatga tcatcgtatc ccttttgaac tgagtggtga cttaagccga
     1681 gtggtaacaa gtatcaatgg attggtggat agtaccgtag cagcgattga agacgaacgt
     1741 aaaatcgaaa aatcaaaaga tgaattgatc acgaatgtca gtcatgatat ccgtacccca
     1801 ctcacgtcca tcattggata cctaggactg atagaagatg gccagtatca ctcagaagaa
     1861 gatcttttaa agtatacgca tactgcttat atcaaagcaa agcagatgaa atctttagtg
     1921 gacgacttat ttgaatacac taaggtacgc cagcctgctg tcccggtgaa tttttctgcc
     1981 tttgacatga tccagttgat cgaacagtta gcagctgatt ttgagttgga agcttctaaa
     2041 aaaaatatcc aaatacttgt tcaatcaaaa gtagactccc ttatcatgga tggcgatacc
     2101 gaaaaacttg tacgtgtctt caataatctt ttgacgaatg cgttgaaata cggaaaagga
     2161 gcaacgaaga tcgtaatcga agtagaacgt atcggttcag aagttgttgc aacagtcaaa
     2221 aataacggag caatgatccc acaacaggca atcgataatc tattcgaccg tttttatcgt
     2281 gtagaagaat ctcgttcaca agcaactgga ggaactggac ttggtttagc aatcgctcaa
     2341 agcattgtgg ctttgcacgg cggatacatt tatgcaaaat cagataagca atggacttct
     2401 ttcatcatgc accttccaat caagaaaaat gaaaaattac ctattgatac acaggaagtt
     2461 attgacgaaa gctgaaatat tcgctattct tattacaatt attagaataa atgaaaaaca
     2521 cagaacccag tacactttat tctttttcag agagctgatg gcaggtgtaa atcagcaaag
     2581 gataatttgg aagttccagt tcgtttacgt gccctttcga aataagaaag gtcggttcaa
     2641 cagccgttat gtgttcaaca agtgcagctg acgctgaact tgggtggtac cgcgaatttc
     2701 agactgattc gtcccaagaa taatgggatg gatcagtctt tttttatttt caaaaaggag
     2761 gaaatcatat gttagatgta aaaatgatgc gacaaaatat tgaagaagta caagaaaaat
     2821 tgatgactcg gggcgtaaaa aaagaaacat tagctgaatt catggaacta gatgaaaatc
     2881 gtcgtaagct actagtcaaa agtgaagaat taaaaaaata tcgaaatgat gtttctgctg
     2941 agatcgccca attgaagcgt gcaaaagaag atgcttctgc taaaatcgct gaaatgaaag
     3001 aagtcggtgg caacatcaaa gcattggata ctgaaattgc tgaagtggat gaaaaattga
     3061 aacaaattgc aactactttg ccaaaccttc cccatgattc tgtgccagtt ggaacagatg
     3121 aagaggacaa tgtagaaatc cgtcgttgga gcgaaccacg tacatttgct tttgaaccaa
     3181 aaccacactg ggaaattgca gaaaatcttg atattttaga ttttgaacgt ggcgcaaaag
     3241 tagccggtag ccgttttgtc tattacaaag gattaggtgc tcgattagaa cgtgctgtct
     3301 acaacttcat gcttgatcag catatttacg aacacggcta tactgaaatg atcactcctt
     3361 atatcgtcaa cagtaaagcg atgtttggta cgggacaatt tccaaaattc aaagaagatg
     3421 ttttccaatt ggagaatact gatctaacat taatcccaac agctgaagta ccattaacta
     3481 actattataa tgatgaaatt ttagatggtg cagatttacc tatttatttc actgcactaa
     3541 gccctgcttt tcgttctgaa gccggaagtg ctggtcggga tacacgagga ctgattcgtc
     3601 ttcaccaatt caataaagta gaaatggtca aattttcgga tgtagagcat tcttacgaag
     3661 aattggaaaa aatgacagct gatgcagaag atatcttgaa aaaattgcat ttgccttatc
     3721 gtgtgatggc cttatcaact ggagacatgg gcttttctgc agctaaaact tatgacttag
     3781 aagtatggat acctgcacaa gatacttatc gtgaaatcag ttcttgttct aactgtgaag
     3841 atttccaagc acgccgcgca atgatccgtt atcgcgataa tgatggaaaa atccactata
     3901 ctcatactct gaatggttca ggacttgcag ttggccgtac agtagctgcc attttggaaa
     3961 actaccaaaa tgaagatggt tctgtcacag ttccagaagc gctcgttcct tatatgggga
     4021 atctgaaagt tattaaataa agaggctgtg aaaaagccgc ttagtttcga gtattaagaa
     4081 aaattttgtg aaaatggctt tccacatttt tgcataaatt ggacttaata ccgagaaact
     4141 ggcttttgaa caccatttat cgagaggttg tgaaatcagc gaattaacct gagtattaga
     4201 gaaaaaaatg gaaaaatagt ccctcatatt ttaccgtttg ttgaactaat accgagggtc
     4261 agctgattga acaccgttta gtggagaggt cgtaagccta ccccccagct cctagttaca
     4321 aggacaaatt caaaaaacag ctcttcatat tttatgaatg ttgtacttgt gattcggagg
     4381 tggcaaggga acactgttta ttcaaaaaga ggctgggaca gaagcgttta actccaagaa
     4441 ataagaagaa attcacgaaa attgcttttc aaatttttgt gaatttcttc ttatttccga
     4501 aggagttgct tctacttccg ccgtttatac gtgtttagag cgtgagacaa aagtgttctt
     4561 tacttttgtc ccacgctctt taatgttttt aagattcaac tgaatagttt ggtgcttctt
     4621 ttgtgatttg tacatcatga gggtgtgatt cttttaatcc actgccgctc atttggataa
     4681 attgcgcttc atcacgtaat tgctgtagat tggctgcccc aacataaccc attcctgaac
     4741 gcaaaccgcc gatcatttgg aaaataatat ctgcaacact tcctttataa gcaacccgac
     4801 cttcgattcc ttctggtact aatttatttg cttcattgac actaccttgg aagtaacggt
     4861 cttttgaacc tttttccatc gcgcctaatg agcccatacc tcggtatgtt ttgaatcgac
     4921 gtccttggaa gatttcgaat tcacctggtg attcatctgt ccctgccaac atacttccta
     4981 gcatcactgc atgtccgccg gcagctaatg ctttgacgat gtcaccagaa tatttgatcc
     5041 ctccgtctgc aataatcgct ttgccatatt gacgagcaac tgatgctgca tcataaatag
     5101 ctgtgagctg aggtacacct acaccggcta ccacacgtgt cgtacaaatc gatcctggtc
     5161 cgataccaac ttttacgaca tctacacctg catcatataa agcttttgtc gcttcagccg
     5221 tcgcaacgtt tcctgcaatc aatgttgcat ctgcaaaagt tgaacggatt tcttgaattt
     5281 ttcggatcac acctgcacta tgtccatgag ctgtatcgat gatgattgca tctgcccctg
     5341 cttctaataa agcattcgca cgctcaaatg tatcgcttgt tacaccaacg gctgctgcta
     5401 caagcaatcg accatgttca tcttttgctg catttggaaa ttcgatcact ttctcgatgt
     5461 ctttgatcgt gatcaatccg cttaaacgac cttcgttatc tacgattggt aatttttcga
     5521 ttttatgttt ttgcaaaatc ttttctgcat cttttagaga ggtacctact ggggcagtca
     5581 ctaagttgtc ttttgtcatc acatcagcaa tcggcatgtg ataatctgtt acaaaacgca
     5641 tgtcgcggtt tgtaattatc cctaccaatt ttctgttttc aagtgtttca acgattggca
     5701 caccactgat acgatatttg ctcatcaatt cttctgcgtc tgctacaaga tgctgtggcg
     5761 ttaagaagaa cggatcaatg attacgccac tttcagaacg tttgactttt cttacttcat
     5821 ccgcttgctg gctgatcgtc atgtttttat ggatcacacc tagtccgcct tgtcttgcca
     5881 tagcaatggc catcttgctg tcggtaacag tatccatact tgcactgatg attggaatat
     5941 tcaacttaat atttttagct aattgtacgc tcatatccac ttcgtttggt aacacgtgac
     6001 tttctgctgg tatcaataag acatcatcaa aagtaaatcc ttttttcgtg aactttgttt
     6061 cccagttgga catttttagt accactcctc taatttagtt tatctattaa aataattgat
     6121 tttttcattt aagtcaatga tctacttgga atcaagttag ctttctcata gaataccaat
     6181 ataaagcgtt tacatctgtg tatattaaaa gagattgtaa aaaagctgtc ctgcatcaag
     6241 taataagaac agccaatcaa aaacagcttc tcatgttttt gaattggttg ggtttattac
     6301 cgcagatgca aacttttgaa caccgtttag tggagaggct gtgaaaaagc tgcttagttt
     6361 cgagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa attggactta
     6421 ataccgagaa actggctttt gaacaccgtt tatcgtaaaa agggactgtg acaagacttt
     6481 tgtcacagtc ccttactatt atttaactat ggataaacaa aatgaggttc tttactaccc
     6541 ctagatatct agcaaaatag ctgatctttt tgctagttta tcttcttggg acggataaac
     6601 ttccaataat cccgtatttt ttcttcaagt agtaacggat tgctaaagca gttgccccga
     6661 taatgataac tactactgga tctaatactg gattgataac tggtggcaat agtgttgtcg
     6721 cagaaaacag tacgacccaa agaagtgtcg ttccacctag gataagcaat gtcttaccca
     6781 ttcctggttt cttgcttcga tctgctccgg gatattcata ttgatagatg tatttgtaca
     6841 tcatataaaa gacccagcca ccgattgcag aacctagaac gagtgtagaa aagccataag
     6901 ctggcgttgt tccacgtgaa aacaatccgg taatcgcaat catgatactt aatagaccaa
     6961 gcaacagcaa cgtattatct aaccacatca ataaaggggt ggatgaattt tttacttctg
     7021 ctggcttatt gatgattgct tccgttcttt cagagactgt cccaaacaat tgacgggctg
     7081 ttcttccgcc tttttgttct gcaactaaag taggcagaat gtcatgaagg gcttttactt
     7141 tttcttcttc agacaaattc gctgcttcta aagatttttt caaatcaaaa atgtactgtt
     7201 gatttctttt ggttaatttt gtttctaaac tattgttttc ttttacgatt gctcgtaatt
     7261 gttctggttc cattatctaa tagtcctcct tagccgttcc ttttctcaac ggtcgtcaca
     7321 aaagacattc taccatattc tacagctagt ttgatagccc ttttacacat taaagcggaa
     7381 taacattacg tcgccgtctt gtacgacata atcttttcct tctaatcgaa cacgtccagc
     7441 ttcttttgct gcatgcatgt ttccgtaatg atccaagtct tcaaaagaga cagtttctgc
     7501 acggataaat ccgcgttcga aatctgaatg gatgattcct gctgcttgtg gtgctttgat
     7561 tccttttttg aatgtccaag cacgtacttc ttgttcccca gcagtaaagt aagtagctaa
     7621 gcctaacaaa tcataagcag cacggatcaa ctgatccaaa cctgattctt cgattcctaa
     7681 agcttctaaa aattccgctt tgtcttcttc atctaattct gcgatttctt cttctgcacg
     7741 agcactgacc acgatcactt ctgcattttc ttctgcagca aagttgcgca cttcttgtac
     7801 ataatgattc gcgtctgcat ctgctacgtc atcttctgag acattggcta cataaagaat
     7861 tggttttgtc gtcaataaaa atagtgattt aacgattttt tgttcttctt cagtaaattc
     7921 gatcgttcgg gcagattttc cttcttccag tacaggtttg attttatcca gtacagctag
     7981 ttctgccact gcatctttat ctttggtttt agcaactttt gctacacgag tatagcgttt
     8041 gttgatagat tctaagtctg ctaacactag ttccaagttg atcgtatcaa tatcttctag
     8101 tggatcaaca cgtccttcta cgtgagtaat attatcatca tcaaaacagc gaacaacgtg
     8161 acaaatagcg tctacttggc ggatatggct taagaattga tttcccaaac cttctccttt
     8221 acttgcgcct tttacgattc cagcaatatc tgtaaattca aaagtcgtcg gaacagtttt
     8281 tttcggatgt acaagttctg ttaagcgttg caaacgccag tcaggtactt ctaccatccc
     8341 tacgttgggg tcgatcgtcg caaagggata gtttgctgct tctgctcctg cttttgtgat
     8401 cgcattaaac aaagttgatt ttcctacgtt gggcaaccca acaattccag cagtcaatgc
     8461 cataaattta ttcactcttt ctctgcattt ttttcaatta ctttttttaa tttcttttca
     8521 aaatctcgac gggtcatcat gacgatatgt ccgcaattca tacatctgat tttgatatct
     8581 gcgcccattc gaatgacttc ccagcgattc gtctggcaag cgtgaggttt tttcatttca
     8641 acgatatcgt gcaagtcgta cataaaaata gcctcctttt tgtttattct tcatcaaatt
     8701 gaatattcaa gatatcaaga attcgagtca aatctttttg agaaagatat tcaatctcga
     8761 tcttaccttt cccatttttt tcttggatag ctacacttgt accaaattta tccatcaaac
     8821 gatcttcgct ttctcggata taatatggtt tttcctttgc tagccttggg atttttttct
     8881 tttcttttcc atcattttga tttaactcag aaacaagctg ttccagttgg cggacagtta
     8941 aattttcagt tactgcacga ttggctaatt tcaagatcaa tgttttattt tttaaaccta
     9001 acagcgtacg ggcttgtccc atagataaac gctgatcttg taccatttcc ttgacaagat
     9061 ccggtaaaga aagcaagcgc aaataattgg cgatataagg tctgctcttt cctaaacgac
     9121 tagctacttc tgcttgtgtt agtttcaggt ttttcatcag catctcatat gcttctgctt
     9181 cttctaacgg attcagatct tctcgctgca agttttccag cactgctact tgcatcatcg
     9241 cttcttcgtc aaagtctcta acgatagcag ggatcgtttc tttttcagct agtttggacg
     9301 ctcgaaaacg tcgctcccct gcaataatct catatccttt tactgcggaa cggcgtacga
     9361 tgatgggttg aaagacacct gattgttcaa tagaattagc tagttcctgc aaagatactt
     9421 cttcaaatgt tttacggggc tgatacggat ttggtcgcag ctcattcaat ggtagctgga
     9481 caacggtatc atcttttaca tccaccgtct ctaagttttc taaatcttga aacagtgcat
     9541 cgattcctcg gcctaatcct ttacttttct tcacgactta ccacttcctt tgccaatgct
     9601 tggtagactt cagctcctcg agaacgtgga tcgtagtcga tgatcggttt tccatgacta
     9661 ggtgcttctg ataaacgaat atttcttgga atgatcgttt cgtaaacttt ttcgcggaag
     9721 tatttacgta cttcttctac gacttcattt cccagatttg ttcgtgcatc atacattgtc
     9781 agtaagactc cctcgatctc taattctgga ttaaagtgtt tttggactaa acgaaccgta
     9841 ttcagtaatt ggcttaatcc ttccaatgcg taatactcac actgaacagg tatcaaaatc
     9901 gaatcacttg ctgtaaatga attgattgtc agatggccaa gagaaggcgg gcaatcgatc
     9961 aaaatataat catactgact gcttacttct gctaaagatc cttttaatct tgattctctt
    10021 gccatcattg acgtcaattc gatctctgct cctgctaatt ggagagtcgc aggcacaata
    10081 ctcaaatttt cgtgttcagt gatcaaagtt gcctcatcaa ttggcaattc attgactaga
    10141 acatcataga tgtctcttgt cacatcaggt tttctgatcc cgacaccact ggtagcattt
    10201 ccttgtgcat ccatatccac tagcaatact tttttgccaa ggctagcaag acaagcacct
    10261 agattcaccg tcgtcgttgt tttgccgacg ccaccttttt ggttcgcaac agatattatt
    10321 tgtgccatct cttctcctcc tatttgattg gctgcttatt aggcagtccg ggctttcttg
    10381 ggtatttctt tggggttggt ttcttttttt gaataacgat gatatgccgt tgatcagaga
    10441 cattcggcaa ggtaaccgcc tcttctttga ggaatttacc acctaataaa gcaatcgctt
    10501 gttttgcttc tgtcaattcc tcttcacttt ttgctgcttt caatgcataa aaatagcctt
    10561 cttgtttagc caagggcaaa cacaattccg ctaacacatt caaacgagca accgcacgag
    10621 cagtgacaag gtcaaatgat gcacgaaagt gaggattttg cccaaatgtt tctgcccggt
    10681 catgatataa ggaagcatcg attcctaata atcgggttaa ctcagataag aaggttattc
    10741 gtttattcag agaatcaacg atcgttatct gcagttctgg aaaggcaatt tttaaaggta
    10801 tgctaggaaa ccctgccccc gaaccaacat cgcataaaga taaaggttgc gtaaagtcta
    10861 cttcaaatgc taatgtaagt gaatcgtaaa aatgcttcag atatacgtct ttttcatccg
    10921 taatagctgt aaggttcatc ttttcgttcc attcgactaa tgtccgataa taaatagcga
    10981 attgattcat ttgatgatcg gtaagctcta tccctttttc tgccaaggat tggcgaaatt
    11041 cttctggtat cataaatatt cctttcattg tgaaacagca attgtttcac agattctctc
    11101 cctactttaa cgcaaaatct ctagacatgc aatccttcca tatggattct taaaaatttg
    11161 aaaagtaaga aaagccgata gactttttct ttctagtatg actcataaaa tatacacaga
    11221 agagagaact agctttgagc aatttctgca aaaactagtt ctctcttcta tttattatta
    11281 cgtattacgc tggttcactg actttcgcaa tcttcccttg ttcgatatag accattagga
    11341 tacttaggtc tgcagggttt acgccactga ttcggctagc ttgggcaatt gtttctggtt
    11401 ggattttctg caatttttgt tttgcttctg ttgctaatcc gttgattgct gcgtagtcga
    11461 tgttttctgg aatctttttc gcttccatgc gttttaattt ttctactttt tccatggctt
    11521 ttttgatgta gccttcatat ttgatttgga tttctacttg ttcgatttct tttcgtgtca
    11581 attcttcatt ttctggaata aaccgtagaa gttctgcata agtaatctca ggacgtctta
    11641 aaaagtcgct tgctagtaca ccatctttta atggtgccgc attaatcgtt gctaaaaagt
    11701 cttggacttc ttctgttggt ttgattcgta cattcatcaa acgtttgatt tcttgttcaa
    11761 ctgcttcttt tttcttcaaa taattcttgt attgatcttc ttttactaag cctacacggt
    11821 gacccatttc tgttaatcgc aaatctgcat tatcatgacg taaaagcaga cggtattcag
    11881 cacgtgaagt cagcaaacga taaggttcgt tcgttccttt tgttaccaaa tcatcgatca
    11941 tgacaccgat gtaaccgtca cttcgtttga tcactaaagg ttcttttccc tgaactttca
    12001 aagctgcatt gataccggca atcagccctt gtccagccgc ttcttcataa ccgcttgtac
    12061 catttgtttg tccagctgta taaagatttt caacgacttt agtttctaat gtcggacgga
    12121 gctggtgtgg ctctactacg tcatattcga tagcatatcc tgtacgcatc atttctactt
    12181 tttctaatcc agcaatagaa tgaagcatgt tgacttgaac atcctctggt aaagaagtag
    12241 ataaaccttg aacatagact tcttccgtat ttaagccttc tggttccaaa aataattgat
    12301 gacgtggttt gtctgcaaaa cgcacgatct tatcttcgat ggatggacaa tagcgagcgc
    12361 ctaccccttc aacgatccct gtaaacattg gggcacgatg taagttgtct cgaataattt
    12421 ggtgagtcgt ctcacctgta taggtcagcc agcaagattc ctgatctagt ttataggcac
    12481 tatctggtgt gctgaagcta aaatgattcg gctctttgtc accaggctgc tcttctgtaa
    12541 cagaatagtc gatcgtactt gattttactc gaggcggtgt tcctgttttg aaccgttcga
    12601 tagcaaagcc aagttctttt agatgattcg ctagtccaat agaaggttga gagttattcg
    12661 gacctgatga atatttcaat tcaccgataa tgatttctcc gcgaagtgct gttccggctg
    12721 taataacaac tgctttggcc cggtagctcg ctcctgtgga cgtcactact ccatgacaaa
    12781 caccatcttc gacgatcagt tcttcgacga ttccttgtct tagcgtcaaa tttggttctt
    12841 tttcgatcgt atgtttcatt tctgttgaat aagcatgttt gtctgcttgt gctcgcaatg
    12901 ctcggacagc tgggcctttt cctgtgttca acatacgcat ttggatatag gttttatcga
    12961 tattcttacc catttctccg cctaacgcat cgatttctcg aacgacaacg cctttagctg
    13021 gtccgcctac agaaggatta catggcatga atgctaccat gtccaaattt attgtcagta
    13081 ataatgtttt tgatcccata cgtgcagcag caagtgcagc ttctgaaccg gcgtgtcctg
    13141 cgccaacaac gatcacgtca tacgcatctg cttcataatg ttccaatcgt ttgttcctcc
    13201 ttttattttc ctaaacaaaa ttgactgaat aattgagtga ttagctcatc ttgtacactg
    13261 tcgccgacaa cttctcctag atagtcccag caacgcgtca tatctatttg aacgagatcc
    13321 acaggcattc ctgaatcaat acctgcaatg acttcttcaa gtgagaggga agctttttct
    13381 aacaacgcga tatggcgggt attagaaaca taagtagcgt ctctttctcc tgtttctccg
    13441 ctgaagaata aatcagaaat agctgattcc aaacgatcta gtccgtcgtt tttagctacg
    13501 gaaattgaaa aaactggttc attttcgatc aatttcttca atttttcttg ttccagctgt
    13561 gctggcaaat ctgttttatt tagaagaatg atccgtttca atccacttgt cgcttccaat
    13621 aattgttcat cttctgctgt cagtggttcg ctttggttta gaacaagtaa gatcaagtct
    13681 gcttctgcta atgcttttcg gcttctttcg accccgatcc gttccaccac atcttctgtt
    13741 tcccgaattc cagctgtatc gattagcttg agcggtaccc cccgaacatt gacatactct
    13801 tcgattacat ctcgagtcgt tcctgcaata tccgtaacga ttgctttttc ttctcttaac
    13861 aaatggttta acaaacttga tttgccgaca tttggccggc cgatgattgc cgtacttaac
    13921 ccttcccgca gaaccttccc ttgcttggat gtagcaagta gcgcttggat tctttgttgg
    13981 atcatctgcg ctttttcaag caataacttc gtagtcaatt cttcgacatc atcatattct
    14041 ggataatcaa tatttacttc tacttgtgct aatgtctcta aaatctcttg tctcaatgag
    14101 cggatcaaag cagacagatt gccgtctaac tgattaagag ctagtcccat tgctttgtct
    14161 gtttttgccc gaatcaaatc catcacagct tctgcctgtg aaaggtcaac acgaccattc
    14221 aagaatgctc gttttgtgaa ttcgcctggc tcagctaatc ttgcaccttc tcttaacaat
    14281 agctgcaaaa tttgattgac tacaacgatc ccaccgtgac aattgatttc tactacatct
    14341 tcccgcgtaa atgtctttgg tgctctcatc acggagacca tgacttcatc gacaagctga
    14401 ttgctcttgg gatcaacgat atgtccataa tggatcgtat gacttggtac ttctgataat
    14461 cgtttgtttc cagattgata aactttatct gctagttgca cagcttgatc gccacttaaa
    14521 cgaacgatac tgattgcacc ttctccaggt ggggtagaaa ttgccgcaat cgtatcaaat
    14581 tctaaagtaa tttcagccat tttttcactt cctttttcat tttgcgcaca aaaaaagtgc
    14641 ccactccacc ctttatgcac aataaacggt gaacttcgca ctttgactgc ttgttcttga
    14701 ttaaattctg gtcatagatt atcacacttg ctataaggaa tcaagtgttt aaaacaatta
    14761 gatgaagttg agcctgttct gcttccatta ccttatattt aattgtcctt ggatgtctct
    14821 ttgcgttctt tggtttattc gaagagaaga tactgtataa acaaggcttt atctttctta
    14881 aaaaaaacgg tacactaaat ggtagcgcta tctaaactat acacttttga aaggagaaaa
    14941 tatgtgagcc cgttcagatc tgctgcattg gaagaagaaa gtgaccctcg gatcaacgat
    15001 gtcgttttat ctacagggaa tatcaaccag aaatatatcg tccgcgatat cgtttttgtt
    15061 gtggaatgct tagaagctga tttgtttgac ccatcttttc ccaaagatga ccttttctta
    15121 acaacgaaga ggaaattaaa gacgaaggta cttgaatatg gtgcgaatgc agtaatcaac
    15181 tgtcattttg agtatcagca aaaaaaacgc gacggaaagt attttctgga actttttgct
    15241 tatggaacag tgatccaatt tatccaaaca acgattggtt aaatgaaaca gacaaaaaaa
    15301 gcggatcaaa actgaagaca gtttcgatcc gcttttttct atcaaagtta gtgactactt
    15361 catcgtatac tctgataaga atgatttcta gtaaaatata cttggtttga aaaactttgt
    15421 caacgtgatt tattcaaaaa gtaatggaat caataatatt ttttagcagg ttctactact
    15481 aaataacgat aaggttcctc accttccgaa tgtgttttta catgttcatc tttgcttaat
    15541 gcagcatgga tttgtttacg ttcaaatgca ggcattggtt ctaagaaaac aggctgccct
    15601 gtccgtttta ctttttcagc cgtgcgatca gctaaacgct gaatgatctc ttggcgcttt
    15661 tcacggtaat tgcctacatt gactactaca gacagcttat ttcttgctaa acgatggatg
    15721 aagacttgtg ccagatattg caatgcattc agtgtttttc catgtttccc aatcagtatg
    15781 ccttgctttt gtgtttctaa atggaaaaca accatattat ttgattctct ttccattttg
    15841 acaagagctg gagcatcaag ctgttttgaa atttcagtaa gataaactgc caattccgtt
    15901 aaagctgctt catcacctag ctcacttact tcttctgttt tttcttcaag aatcgtttcg
    15961 ttgactacct cgatctcagc tgttggttct tcttccaaaa tttcttctac agtctgttct
    16021 actgtttcag aaactttttc gctgatactt ggctggatcg aaagccgtgc attctttcga
    16081 cccattccta ggaaaccttt ttttccttct tccagtattt cgatttcgac ttggtctttg
    16141 gccaaaccca aatcagccag acctagttgg acagcttcgt ctattgttgc agcttcataa
    16201 atcggcatta gcattacctc ccctattatt tccgtttttt cttaggattc attgctttct
    16261 taagagcacg ttctctttcg cggattctcc gtgcttcttc ttcacgctct tttcgaattt
    16321 tgaaagggtt gttgatcagc agcgtttgta caacttggaa ggcattggaa actacccagt
    16381 ataatgaaag accgctggct aaattgacac ccatcactaa aatcattaca ggcatcacga
    16441 aattcatgat cttcattgat gcattcgatt caatttgact catgctagat aaatacgtac
    16501 ttgcaaaagt aaagattgct gctaaaatcg gcaaaataaa tgttggatcc gcgttcccta
    16561 agttcaacca taagaaatgc ccttgtttca actctggtac acgtgaaata gattgccata
    16621 acgccatcaa gattggcatt tgtactaata aaggaagaca accagcatat ggattgacgc
    16681 cattttctgc atataaacgc tgctgctctt ctcttaactt actttgtgtt tccggatctc
    16741 ttgaactata ttgttgctgc agtgctttta atttcggttg taattcttgc gttttacgca
    16801 tgctctttgt ttggaaatgc atcaacggca ataggatcac gcggatgatc agtgtaaata
    16861 aaatgatccc tatccctgca ttaccaaatg acaacgcctt gatcgcctca gcaaagtaat
    16921 aaacaatata acgatcccaa attcctgtac tctgtgcgct gacttcccca gttccgcaac
    16981 cggataagac gatgaccaaa ctaacgatac cggccatcaa aagtaaacgt ttgtatttct
    17041 tcacttactc ttttcctctc tgtcgattat ttttgcaagt tttaagacgt ggactaaatt
    17101 ggagcgaacc tcatcataag tcaacccctt cacacttggt ctagcaatca caataaaatc
    17161 caactccgga tcaatttctt cttttataga ataaactgct gctcggattt ttcgtttgac
    17221 ttcattgcgg tttaccgcgt tgccgacctt ttttcctaca gataaaccaa ctcgaaaatg
    17281 aggctgtccc ggtttttcca aacggtaaac gacgaatttg cggttagcaa aagaatctcc
    17341 cgtatggaac acggcttgaa actctcgttc tttttttact cgatacgctt ttctcattag
    17401 ttttctttcc ttttctatct ctcacttacg ctcataatca taccataatt acgattgtcc
    17461 tttcatcatt tccctaaaaa agagtataaa aaaaaccact gaaaccccag tggcctaagc
    17521 tgaaagaact tttcttcctt tgcgacgacg gctagctaac acacgacgtc catttttagt
    17581 actcatacgt ttacggaatc cgtgaacttt ttgacgttta cgtttatttg gttggtatgt
    17641 tcttttcata tattccacct ccaaaatgtt cttatctatt ttataaacac agacatactt
    17701 tgatagtata acgacaaagt agtgattttg tcaatataaa atagaagatc gattgttaaa
    17761 acttatccac aagattattt ttttctatgg gaatcctatg tggaaaaagt tatgcacagg
    17821 gattatccac agataataaa aggctggttt tacacagaaa acacacgtgt aaaaaaagta
    17881 atccacaatc aggcgatttc ctgtgtattc cgtctcctaa ctattggtat atctgtattt
    17941 tttatccaca gacgcaagag gaaatctatt ggtttttacg agttttccac ctgtgcatta
    18001 gtggtgtgga aaactttttt tgacaactgt gtttttctct tttttctttt tgtcgattgt
    18061 gtggataatt gtaattaaaa aatttttttc ttcggtttct gtggaaaact attgaaaaaa
    18121 atgctaaatt agtactagtt attcactttt taatgaagga ggaggcctta tatggtatcc
    18181 ctcgatgctt tatggaatga attaaaagca acataccaaa aggatttatc gcctgctagc
    18241 tataatacat ggatcgaaac agcgaaccct cgaacccttg atcaaaacca gctcgttgtt
    18301 gaggttccta gcaagattca taaagaatat tgggaaaaaa acctggcgac aaaaatcgtt
    18361 gaagtcggtt atatgttatc aggaaatgag attatccctc gctttattac tggcgaagaa
    18421 gcagagcaag aagaagttat agaagaaaaa aatccaaaag ttgtggcacc tagtccgcta
    18481 aaaaaagcca tgctgaaccc taaatatacc tttgatacgt ttgtcattgg taaaggaaac
    18541 cagatggctc atgcagcagc gctcgttgta gcagaagatc caggttctat ttataacccg
    18601 ctcttctttt atggaggcgt gggacttggt aagactcact tgatgcatgc aattggtcat
    18661 caaatgctgc aaagtcagcc taatgccaaa gtaaaatatg taagcagtga aacttttgct
    18721 aatgatttca tcaattcgat ccaaaacaaa acagcagaag agttccgtca agaatatcga
    18781 aatgttgatt tactgctagt ggatgacatt caattttttg cagaaaaaga agctacgcaa
    18841 gaagagtttt tccatacttt caatgccttg tacaatgaag ggaaacaaat cgtactaacc
    18901 agtgatcggt tgccaaacga gattccgaaa ctgcaagaac gccttgtttc tcgctttgca
    18961 tgggggctgt ctgttgatat tacaccgccg gatcttgaaa caagaacagc gattttacgt
    19021 aaaaaagcgg cggctgaacg tctagagatc ccagatgaca cactaagcta catcgcagga
    19081 caaattgatt ctaacattcg tgaattagaa ggtgcgcttg ttcgagtgca agcttttgct
    19141 gcgatgaata gtgaagatat ttcgactagt ctagctgcag acgcactgaa aacgttaaaa
    19201 tcaggaaaag gacatcctca attgtcaatc ctgcagatcc aagaagaagt ggcaaagtat
    19261 tatcacatcc aattgaaaga tctcaaagga aagaaacgcg tcaaatctat tgttgttcct
    19321 agacaaatcg ctatgtattt ggcacgtgag ctcacagata attctttacc gaaaatcgga
    19381 gctgaattcg gtggcaagga tcatacaacg gttatccatg ctcatgaaaa aatccagcag
    19441 ctgatggatt ctagtgtcag tatgcaaaat gaagtatcag aaatcaaaaa ctttttacta
    19501 aattaatttg tcgattctat caactgaaaa tagcatgtgg ataaaagaaa aaaacgttca
    19561 aaagttatac acactttttc cacagctgtt ttttcgtttc tctcttacgt tttttgagtt
    19621 ttccacagaa tcaacatgcc ctattacttt tattattctt tttaactaat aataaataaa
    19681 caaacattca aaggagatac atcatgaaag ttactttaaa ccgagctagc tttatgcagg
    19741 aattgcaaac tgttcaacga gctatttcaa gcaaaaccac gatccctatt ttgacaggtg
    19801 taaaaatcac actgacacaa gaaggtttga ctttgacggg gagcaacgct gatatatcaa
    19861 ttgaaacttt tttgtctgtt gaaaacgaaa aagcaaatat gcaaatcgaa tctactggtt
    19921 ccattgtttt acaagcacgt ttctttagcg aaatcattcg gagacttcct gaagaaacat
    19981 ttactttaga agttttagaa aataaacaag tagcgatcac ttctggaaaa gcgaatttta
    20041 tcgtaaatgg attagatgca gataactatc ctcatcttcc tgttgtcgaa agccataacc
    20101 agatgaaatt acctgtacac gtattgacta aactaatcaa cgaaacagtt tttgctgtct
    20161 cacaacatga gagtcgtcca atcttgacag gtgtgcattt cattttatct gataattctt
    20221 tattagctgt agctactgat tctcaccgtc taagtcaacg cgtgattcca gtagaacaag
    20281 cggctgatca ttttgatatt gttattcctg gaaaaagttt gatcgaatta tctcgctcat
    20341 taacaaatga agaagaaatc gtcgaaatca gcattatgga aaaccaagtg ttgttcaaaa
    20401 cagaaacgat gtatttctat tcccgtttgc tagaaggaaa ctatccagat accaatcgtt
    20461 tgattccttc aagttttaat acagaggttg aattttctgt tcctagcttt ttagcggcga
    20521 tcgaacgggc ttctttactt tctcatgaag gccgtaacaa catcgttcgt ttatctattc
    20581 gtccagatgc ggttgtttta tacggaaatt cgccagaaat cgggaaagta gaagaaagct
    20641 tgagttatac agcaagcagt ggcgatccat tagatatttc tttcaatccg gattatatga
    20701 aagcagcgtt gcgtgcattt ggagatatga gcatcaaagt gaaatttatc tctgctattc
    20761 gtccatttac attggaacca acggaagatg gcgttcaatt tattcagctg attactcctg
    20821 tacgtacaaa ttaacaatga ttttcaatgt tcttgaaaat ttaattgaaa agaaatagaa
    20881 aaaataaaat tttaaacaga aggccctaaa atctctttta aggctttctg tttatttttg
    20941 tttaaatcac cttttttaga ttaaatcgtc ttatatggaa aaatatatgg ataaatttgt
    21001 tttattgcga aaaaaaaggt ataatagagt atacttttaa taatgaaaat gagggatggg
    21061 cattgaaaca acaagtcatt ctaaatacgg aattcatgac gttgggccaa atgttgaaag
    21121 aagtcacagt tatcggtagt ggcggacaag caaaatggta tttggcagaa aacactgtgt
    21181 tagtcgatgg cgaaccagaa aatcgtcgtg gacgcaaact ttatcccggc atgatggttg
    21241 aagttccaga agtaggaact ttttttatgg taaaaaaagg aaacgacgat aatgaggctg
    21301 aataagctgt atttaaaaaa ttatcgaaat tacgaagagc tgaacatcga attttccaag
    21361 aacctcgtca tctttttagg agaaaatgcg caaggaaaaa cgaatctttt ggaaagtatc
    21421 tacgtattag ctatgacgcg aagtcatcgg acaagtagtg agcaggaatt gattggctgg
    21481 actgacgatc aggcgatgat tcaaggagag atcacaaaag gttcatccac tcttccatta
    21541 gaaatcttat tatctaaaaa aggccgaaaa accaagatca accatatcga acagaaaaag
    21601 ttaagtactt acgtgggaca aatgaatgtc attttatttg caccagaaga tctttcttta
    21661 gtaaaaggca gcccgcagac caggcggaag tttttagata tggaattagg ccagatcaat
    21721 ccaatctatc tttatgatct tgtccaatac caagcaattt tgaaacaaag aaaccagtac
    21781 ttgaagcaat tgaatgaaaa aaaacaaact gatttgcttt atttggatat tttgtccgaa
    21841 caactagcag cgtttggcag caaagtattg aaagcaagag cacagttcgt caagcgattg
    21901 gagttttggg ctaattcttt gcatcagcaa atcacccatc aaaaagagca gctggaaatc
    21961 gagtatctca ccgcagtcga ttctttagaa acacatacgc aagagcaaat ccaagaacaa
    22021 tttctcgcac ttttgaacca aaataaaaag aaagaccttt ttcggggaac aacgacagtt
    22081 ggtcctcatc gtgacgatct ttcctttttt attaatcaga aaaatgtgca gacttatgga
    22141 tcgcaaggac agcaaagaac aactgcacta agtgtcaaat tagcagaaat cgatttgatt
    22201 aaagaagaga caggggaata tccaatcctt ttgttagatg atgtgatgag cgagctggat
    22261 gataatcgtc aactccatct gctagaaaca atcgaaggaa aagttcaaac gttcttaaca
    22321 acaacgacac ttgaccatgt aaaaaataaa atgactgttg aacctgagat tttttatgtt
    22381 caacaaggga aactaaaagg agaagaaact gaatgacaga agaaagaagt ttagtagaac
    22441 gcgctaaaga gtatgatgcc agtcagattc aagtacttga aggacttgaa gccgttcgta
    22501 aacgacctgg catgtatatc ggttcgacta gttctgaggg tctgcatcac cttgtttggg
    22561 aaattgtcga taattcgatc gatgaagtat tagcaggttt tgcaacgaaa atccatgtga
    22621 ttattgaaaa agacaacagt atcaccgtta ttgacgacgg tcgggggata cctgtagata
    22681 tccaggcaaa aactggacgt cctgcagttg aaacggtctt tactgtttta catgctggag
    22741 gaaaattcgg cggtggtggg tacaaagttt ctggtggact tcacggagta ggatcttctg
    22801 ttgttaacgc gctttctaca cagcttgatg tcaaagtata caaagaagga aatgtgtact
    22861 atcaagaata tcgtcgtgga gctgtagtgg acgacttaaa gattatcgaa caaacggatc
    22921 gccatggaac aacggttcac tttacgccag accctgaaat ttttacagag acaactgagt
    22981 ttgatttttc aaaattggct acccggatcc gtgaacttgc tttcttgaac cgcgggatgc
    23041 gtatatcgat tgaagacaaa cgagaagaag aaccagtcat caatgaatac cattatgacg
    23101 gcgggattaa aagttatgtc gaatacttga atgcaaacaa aaccgtgatt tttccagaac
    23161 ctgtatattt ggaaggtgaa cagcaagata tcgcagttga agtctctatg caatatacag
    23221 acggctacca ttccaatatc atgagttttg ccaacaatat ccatacgtat gaaggcggaa
    23281 cacatgaatc aggattcaag actgctttaa ctcgtgtgat aaatgattat gcccgaaaac
    23341 aaaagctgat gaaagaaaat gacgacaact tgaccggtga agacgtgcga gaaggattga
    23401 cagctgttat ttctatcaag catcctgacc ctcaattcga aggacaaaca aaaacaaaat
    23461 tgggcaattc cgaagtacgg acagtcactg atcggttatt tagcgaacat ttcatgaaat
    23521 tcttgctgga aaacccaagt gtgggccgtc aaattgttga aaaaggatta ctagcttcca
    23581 gagctcgtct agcagcgaaa cgtgcgcgtg aagtaacgag acgtaaaggt gctttagaga
    23641 ttagtaatct gccaggaaaa ttagcggact gctctagcaa cgatcctgaa aaatgcgaat
    23701 tgttcatcgt cgaaggagat tcggccggcg gatcagctaa gcaaggtcgt aatcgagagt
    23761 ttcaagccat cttgcctatt cgtgggaaaa tcttgaatgt tgaaaaagca agcatggaca
    23821 agatcttggc aaatgaagag atccggtctt tatttactgc tatgggtaca gggtttggag
    23881 aagattttga tgtatcgaaa gctcgctacc acaaattagt tatcatgact gatgccgatg
    23941 tcgacggcgc gcatatccgt acattgctgc tgactctttt ttatcgttac atgcgtccta
    24001 ttgttgaagc tggatacgtc tatattgctc agccaccttt atacggggta aaacaaggga
    24061 agaatattac gtatgtacaa ccaggaaaaa atgcagaaga agagttgaaa caagtcgttg
    24121 cttcacttcc tgcctcacca aaaccaagcg ttcagcgtta taaaggactt ggagaaatgg
    24181 atgatcatca actatgggaa acaactatgg acccaagcaa tcggatgatg gcccgcgtca
    24241 gtgtggacga tgctattgca gcagatcaga tatttgaaat gttgatgggg gatcgagtag
    24301 aaccccgtcg tgcattcatc gaggaaaatg cacactatgt gaagaactta gatatttaat
    24361 catgaaggag gaaaaagaat gagtgaagaa atcagagaaa acatccatga tgtcaatcta
    24421 accagcgaaa tgaaagactc cttcatcgat tatgcgatga gtgttattgt cgcacgtgca
    24481 cttcctgatg tcagagatgg tctgaaaccc gttcatcgcc gtattttata cggcatgaac
    24541 gaattaggtg taacaccgga taaagcccat aaaaaatctg ccagaatcgt cggagatgtc
    24601 atgggtaaat accatcctca tggagactat gcgatctatg agtcaatggt acggatggca
    24661 cagccattca gctaccgtta tatgctagtg gatggtcatg gaaactttgg ttctgttgac
    24721 ggtgacggtg ccgccgctat gcgttatacc gaagcacgga tgagcaaaat cgctacagaa
    24781 atgctgcgtg atatcaataa gaacactgtt gatttccaaa gcaactatga tgatacagaa
    24841 aaagaaccag ttgtactacc tgctcgcttc ccgaatcttt tagtgaacgg aacaacgggg
    24901 atcgccgtag gtatggccac gaatatccca cctcataact tgtctgaggt agtagcggct
    24961 atcgatttgc tgatggataa tcctgatgtg acgaccaatg aattgatgga agtattacct
    25021 ggaccagatt ttccaacagg tggtttggtt atgggaaaat caggaatccg aagagcgtat
    25081 gaaacaggta agggttctat taccgtacgt gcaaaagttg agattactga gatgccaaat
    25141 ggtaaagaac ggatcatcgt gacagaattg ccttatatgg tcaataaagc aaaattgatc
    25201 gaacggattt ctgaactgca cagagacaag cgtatcgaag ggatcacaga tttgcgggac
    25261 gaatcttccc gtgaaggtat gcggatcgtc attgacatcc gtcgtgacgc cagcgcatct
    25321 gttatcttga ataacttata taaattgaca tccttgcaaa attcatttgg attcaatatg
    25381 ttggcgatcg aaaaaggtgt gccgaaagtt ttgagcttga aacaaattct tgaaaactat
    25441 atcgaacatc agcgcgaagt catcacaaga cggacagtct ttgaaaaaga aaaagcagaa
    25501 gcaagggcac acattttaga aggtttgcgt attgctttgg atcatatcga tgaaatcatt
    25561 gcgattatcc gcgggtctaa atcagatgac gaagcaaaag cgacgatgat cgaacggttc
    25621 gatttatccg atcgccagtc tcaagctatt ttagatatgc gtttacgccg attgaccggt
    25681 ttggaacggg aaaaaatcga aaatgaatac caagaactct taaaactgat tgaagattta
    25741 actgacattc tggcaagacc agaacgtgtt acagaaatca tcaagaatga attagcagac
    25801 ttgaatcaac gatttggtga taaacgacgc acagaattac tagtcggtga ggtcttaagt
    25861 ctggaagatg aagatttaat cgaagaagaa gaaatcgtta ttacattgac aaacaatggt
    25921 tacatcaaac gtttggcaaa taatgaattc agagctcaac gaaggggtgg acgtggtgtc
    25981 caaggaatgg gtatccacaa tgacgacttc gtcaaaaatc tggtttcttg ttctacccat
    26041 gatacattgt tattctttac gaataacgga aaagtgtatc gggcaaaagg atacgaaatt
    26101 ccagaatacg ggcgcacagc caaaggaata ccaattatca atttactagg tatcgattcg
    26161 agtgaaagca tccaggcaat cattgcggtg acgggagaag cagaagaagg ccactatctc
    26221 ttctttacga cgcgtcaagg tacagtaaaa cgtacttctg tcactgcttt tgctaacatc
    26281 cgaagtaatg gtctgatcgc aattggtttg aaagaagacg atgagctcgt caatgtgcta
    26341 ctgacagatg gtcaatctaa tatcattatt ggaacacata acggctactc tgtcactttc
    26401 aaagaagaag cagtccgcga tatgggacgt acagcttccg gggttagagg aatacgcctg
    26461 cgtgaggaag attatgtcgt tggggcagcc ttaatgaagg aagatcaaga agtattagtg
    26521 atcacagaaa aaggttacgg aaaacggaca aaagtatcgg aatatccagt gaaaggccgc
    26581 ggaggtaaag ggatcaaaac ggcgaacatc actgaaaaaa atggtccact agctggattg
    26641 accactgttt ctggagatga agacatcatg ctgattacag ataaaggtgt cattatccgt
    26701 ttcaacgtat cgactgtttc tcaaactgga cgttcaacat taggcgtacg tttgatgaag
    26761 atggaagctg atacgaaagt tgtcacgatg gcagcagtcg aaccagaagc tgcagaacaa
    26821 acagttgaag aacaaggatc agaagaatag ccatcaagac taattgtgta agctagcaag
    26881 aatgaccgat taaaaaatct ggttattcct gctggctttt ttgattagtt gaatttctct
    26941 taaaatattc gaaactgttc attctgtatt gcttttgacc aaaatagagt gtataatcag
    27001 agcttgtgag tagtctaatt aattagataa ctctccttgc tcttaggaac ctaagagccg
    27061 aaagtccaca gggaggtgaa tatcaatgga aaacacgaaa tatgaaatca tgtacattat
    27121 tcgtccaaac attgatgaag aagcaaaaac tgctttaatc gaacgtttcg atgcaatctt
    27181 gaaagataac ggagcagaag ttatcgaatc aaaagattgg gaaaaacgcc gtttcgctta
    27241 tgaaatgaac ggttaccgtg aaggtatcta tcacatcgtt aaagtatctt ctccatcatc
    27301 agcaaatgct gtcaatgaat ttgaccgtct tgctaaaatc aacgacgata tcattcgtca
    27361 catgattgtt aaagaagaag cttaattgtt gtttcatgtg aaacaataga aaacgatgag
    27421 aggagatgac tattttgatt aataatgttg tattagttgg acgtctgacg aaagatccag
    27481 atttgcgtta cacagcaagt ggtacggcag tcgcaacatt tactttggct gtgaatcgta
    27541 attttacaaa ccaaagcggc aatcgcgagg ctgattttat caactgtgtg atttggcgca
    27601 aatcagcaga aactttagca aactatgctc gtaaaggaac acttttaggt gttactggac
    27661 gtatccaaac tcgttcttat gataatcagc aaggacaacg tgtatacgtg acagaagtag
    27721 tagctgacaa cttccaattg ctggaaagtc gttctgcatc tgaaaatcgc caacaaagcg
    27781 gcggattcca aagttctggt caatcagctg gcggatttgg cggaaacaat aactctaatc
    27841 aaacatctca atcatccaac ggtatgcctg atttcgaccg tgatacttct gacccattcg
    27901 gctcaagttc aacgatcgac atttcagacg atgatttacc attctaaacg aatttgatag
    27961 gagggaaata gaatggcaca acaaagaaga ggcggacgta aacgtcgtaa agtagactac
    28021 attgctgcta accatattga atatatcgat tataaagata tcgaattact aaaaagattt
    28081 atttcagaac gcggtaaaat cttgccacgt cgtgtaactg gtacaggcgc taaaaaccaa
    28141 cgtaaaatta ctgttgcaat caaacgcgct cgtatcatgg gcttgctacc tttcgttagc
    28201 gaagactaat aaatcctagg aattgaatga ctgatccttt tgatcagcta ttcaattcct
    28261 ttttttctgt aaaaataacc tctattcgtt tagtcgctcg aatgacgaaa gttatggtaa
    28321 aatcaaatta gtcatatatg ggaggaaaat tatggaaaat aaaaacaatc atttatcccc
    28381 gaaacctctc ttccttatcc tgtttatatt aatcgaagta ttggtagtct taattttacc
    28441 atttcgtttt gttagcgctt cggtcattct attgatgaat ttatggggtg ttcgctattg
    28501 gttgaaaatg aaacgttggc ttattttaaa taaacgtgaa aaaatccagc aggcttcgac
    28561 tgtagctgaa accaatctag cttatgtctc agaagtcatg cctgtaggag tgattgctta
    28621 tcagccatca agccaaaaaa tcgaatggct caatccatta gcattgaaaa tcaaagatca
    28681 aagtggatta acagaggaag aattgctaga tacttttttt actgcaaaag aaaaaaagaa
    28741 aaaccaagtc tatctagcag ataaaacatt tcagtttgat atggatacag taaagggtgt
    28801 tgtttatttt aatgatatta cccaaaacca gttgttaaaa ctccatcaga cgaacagtca
    28861 gccggtgatt ggtattttat ctattgataa ctatgcagat gccattgata aattggatga
    28921 caaagagatt tcttatttga actctttcgt cactacacta gtttctgact ggatgaatga
    28981 ataccatgtc tttttcaaaa gaatcaacgc agaacggttt ttcttcgtag cacagatgat
    29041 cgatctgaaa aagatgatgg ataaaaaatt tgatttgctg gatcgctttc gagcagaagc
    29101 tgaaaaacag agctcgccta tcacccttag tatggggatt gcttatggct caagaaccct
    29161 cgatgaaatc ggtggagaag ctcagaataa tttagatgtt gctttagtcc gtggaggcga
    29221 ccaagttgtc gtgaaagagg taaaagaagg agcaaaacct gtttattatg gggggaaatc
    29281 tgctaagaat gtcaaacgca cgcgtgttcg ttctcgagcg atgagtaccg ctttgcgtcg
    29341 gatttttgat gaaacaggcg atgtgtttat catggggcac aagtttccgg atatggatgc
    29401 tttaggctct gcttttggtg tcagttgtct ggcacgcttc aaccagaaaa aagcttacat
    29461 cgttatcaac gagaacgaga tcattccaga tgtagaacgg tgtcttgaag aaatccataa
    29521 gcatcctgaa ttagaaatgc aactaatctc tccagaacgt gccatagagc tgaaaaaaga
    29581 agaggacctc ctcgtgatgg tggattacca taaaccttct ctatcgatct ctcagggcct
    29641 atatgagcaa tttgataaga ttgtgatcat tgatcaccat cgtcgtgggg aagagtttcc
    29701 aagtaaacct ctgctgactt atatcgaatc ttcagcttct tcagcttcag agctagtttc
    29761 tgagctgatc caataccaaa gcagcaaaac aaatcgctta gatcgttttg aggccacatt
    29821 attgcttgca gggatggttg tagatacaaa tagtttcaat gtccgtacaa ctgcacgaac
    29881 ttttgacgtt gccagctatt taaggtcttg tggagcagac gcatccttag tacaatattt
    29941 attgagctcg gatttagcga catacttgga gatcagcaat ttgattgctg gaagcgacta
    30001 tgtgacttct gatattgttg tggcggcagg gacagacgaa aaagagtata atagtgttat
    30061 agcagcaaaa acagcagata cattgctttc gatgatcaat atcaatgcag ctttcgtcat
    30121 tacaaagcgg acagacggct tgattgggat cagtgccaga agtaccggca cgatcaacgt
    30181 ccaaatcatc atggaatcct taggtggcgg aggacacttc acaaacgcag ctactcaact
    30241 ggaaaatacg acagttgagg aaacaaaaca gaagctattt gctgcaatca aagaaaatat
    30301 gaatcaaata tatgataagg agtaatccaa atgaaagtaa tttttttaca agatgtaaaa
    30361 ggaaaaggta aaaaagggga catcaaagaa gttccagcag gttatgcaca aaattatcta
    30421 atcaaaaata acttggcaaa agaagcaacg aaaagcagta tcagtcagtt agcaggacaa
    30481 aagaaagcac aagaaaaaca cgaagctgaa atcttggaag aagctaaaaa gttaaaagaa
    30541 ttcttggaaa aagaagatac tgtagtcgaa ttgaaggcga aagcagggga agacagccgt
    30601 ttgtttggtt cgatcccttc aaaacaaatt gctgaagggt taaacaaaca atacaaaatc
    30661 aaattagata aacgaaaaat cgaattagaa aatccgatcc gttcactagg ctacacaaac
    30721 gtacctgtta agcttcatca tgaggtgacg gctacgatca aagttcatgt cgtacaagaa
    30781 taacaaatct tgatagcgat gttcagctgg taagtataac cagaaggaaa aaagacaaac
    30841 cgaaatttat ctgagaaaac agctgcagca atgaaagcaa aagctgcaaa tcgatttcag
    30901 attgatttcg gtttcttttt tgggaacagc aaaatagcat aaagaaaacg agtataataa
    30961 aagagaacta tttttttatt acactttcgg tacgaatgat gacttttctc tcattttctt
    31021 gtaaaatgaa gcaattgaag acaaggagcg atacgtatga atgaagtgtg gcaggatcga
    31081 atcccaccgc aaaatattga agctgaacaa gcggttttag gctctgtttt tcttgacgca
    31141 gaaacgatca ttgatgccat ggagtacata gagccaaaag acttttatcg tcgtggccat
    31201 caaattattt ttgagacaat gatcgagtta aatgatcgta atgaagcgat tgacgtggtt
    31261 actgtcaaag accggctgga acaagccaat ttgttagaag atgccggtgg tttaagttat
    31321 ctctcagact tggcattagc agttccgaca gcagcaaata tcgtctacta tgcgaaaatc
    31381 gttgaagaaa aatcattgct gcgtacattg atccagacag caacaggaat cgttacgaaa
    31441 ggattcgagc aaggagaaga agttcaaaca attttagatg atgccgaacg cagtatcttg
    31501 gaggtttcgg aaaaaagaaa tcgaagcggc tttttatcta ttgctgaagt actgaactcc
    31561 acgattgaaa atatcgatcg actagctcaa aacaatgaag aaatcacagg tctaccaact
    31621 ggctatcaag gtctggataa aatgacagca ggtttccagc ccgaagaact aatcattctt
    31681 gctgcacgtc cagcggtagg taaaacagcg tttgcattga atattgctca aaatgtagga
    31741 acaaaaacag atcgttctgt tgcgatattt agtttggaaa tgggggcaga atctcttgta
    31801 aatcggatgc tttgtgcaga aggttcgatt gaggccagcc atttacgtac aggtcagctt
    31861 tcggaagaag aatggtcgaa tctgatcgtt gcgatgggga gtctttctcg agcaaatatt
    31921 tttatcgatg atacaccagg gatcaaaatc tctgaaatcc gtgcgaaatg tcggaaacta
    31981 gcgcaagaaa aaggcaatct aggcttgata ttgatcgatt atttgcagtt gattgaaggt
    32041 aacggtaaag agaaccgtca acaagaagta tcagatatct ctcgccaact gaaaaaactg
    32101 gcgaaagagc tgaaagtacc tgtcattgct ctttcacagt tatctcgtgg agtagaacag
    32161 cgacaagaca aacgaccagt gctaagtgat attcgtgaat ccggatcaat tgaacaagat
    32221 gcggacatcg tagccttctt gtatcgagat gattattatg aaagagaagg cggagatgac
    32281 gatgatggaa acgagccaaa aaatgacaac gtcatcgaag tcatcatcga gaagaaccga
    32341 agcggtgcac gaggaacagt tgaactactg tttatcaaag aatacaataa gttttcgtcg
    32401 ctttcgccaa gagaagaatt ttaaagaaga ggttgtgagc cttgagcaat cccgagagct
    32461 ctcgtaagaa gatgcaagga gtaaccgcag gaacgactag agtacttaat ttaaacagat
    32521 ctccaaaggg attgtgacaa aagtcttgtc acagtccctt tttccgaata aacggtgttc
    32581 aatcagctga cccttggtat tagctcagca aacgtcaaaa tatgaggaac tattttgacg
    32641 tttgtttctc taatactcag gtcaaaacgc tgatcttacg acctcttttc cttaaacggt
    32701 gttctcctgc caactcctcg gtcacaagtc acaatatcat caaacatgag aagcagtttt
    32761 ttgaaattgc tccttgtgac tcagagttaa acggcaggct cacaacctct ttcttaaacg
    32821 gtgttcaaaa gcttgcatct gcggtaatac gcccaatcaa acgaaaaata tgagaagcta
    32881 tttttgtttg gctgttctta ttacttgatg caggacagct ttttcacaac ctctgattca
    32941 cggtgttcca aaagtagctt cttcgaaaaa taagtcgaaa tttcacaaaa atttgagaag
    33001 caattttcgt acattccttc ttatttcttg aagctgacca cttctgttac aacctctttt
    33061 ttaataacca ttctaaaaag ataaagttcg ttttttaagc gtttttataa aataaaaata
    33121 aaaatcattc gattttattt gaaatatgta tctattattg atacaatggt tcaggattaa
    33181 ataatataga acgaggtgtt cacatgtcat ctgtagtagt agtaggtacg caatggggcg
    33241 atgaagggaa aggaaaaatc acagactttc tcagtgaaaa tgctgaagtg attgcacggt
    33301 accaaggtgg cgacaatgca gggcacacaa ttaagtttaa cggtgtgact tataaactgc
    33361 atttgattcc ttctgggatt ttttataaag acaagatcag tgtgatcgga aacggcgttg
    33421 tagtcaatcc taaatcattg gttaaagaat tagcttattt acatgaaaaa ggtgtagaaa
    33481 caagtaattt gcgtatttct gaccgcgcgc acgtaatctt gccttatcat atcaaattgg
    33541 accaattaca agaagatgct aagggcgaaa ataagattgg tacaacgatt aaaggaatcg
    33601 gacctgccta tatggataaa gcagctcgtg taggtatccg tattgcagac ttattagata
    33661 aagaaatttt tgaagaacgt cttcgtttga atctagatga caaaaaccgt caatttgtaa
    33721 aaatgtttga ttcagaacca cttgattttg acgatatttt tgaagaatat tatgaatacg
    33781 gacaacaaat caaacaatac gtcacagata cttccgttat cttgaatgat gctttggatg
    33841 caggcaaacg cgtgttgttt gaaggcgcac aaggtgtaat gctggatatc gaccagggaa
    33901 cttatccttt tgttacttct tctaacccag tagccggtgg ggtaacaatc ggaagcggtg
    33961 tagggccttc aaaaatcaat aaagttgtcg gcgtctgcaa agcctatacg tcacgtgtcg
    34021 gtgatggacc atttccaact gaattatttg atgaaacagg agaacaaatc cgcgaagtag
    34081 gacgagaata cggtacgaca actggtcgtc cgcgtcgtgt aggctggttt gattctgtag
    34141 ttatgcgcca ttctaaacga gtttcaggta ttaccaacct atctttaaac tcgatcgatg
    34201 tattaagtgg attggaaaca gtaaaaattt gtacggctta tgaattagat ggcgaactaa
    34261 tctaccacta tccagcaagc ttgaaagagt tgaaccgctg caaaccaatc tatgaagaat
    34321 tgccaggctg gtcagaagac attacaggat gcaaaacact tgcagaactg ccagaaaacg
    34381 cacgtaacta tgtacgtcgt atctcagagc ttgttggtgt acgtatctca acattttctg
    34441 tcggacctga tagaacacaa acaaacatct tagaaagcgt ctgggcgcaa atctaaggat
    34501 aaaaacgacg actgaatcag gacgttctta ccagagcgag tcgaagtgtt tatctatacg
    34561 ataataataa cttgaacact gtttattcag aataagggac tgtgacaaaa accgtgtcac
    34621 agtccctttt tccgaacaaa cggtgttcaa aagcttgcat ctacggcact aagcccaatc
    34681 agatgaaaaa tatggagtgc tatttttatc tgattgttct tactgcttga tgcagagcag
    34741 ctttttcaca acctctccac taaacggtgt tctcctgcca actcctcggt cacaagtcac
    34801 aatattcaac aaacatgaga agctgttttt tgaaattgtt ccttgtgact cggagctaaa
    34861 cggcaggctc acaacctctt ggtaaacggt gttcaatcag ctgaccctcg gtattagctc
    34921 aaaaaacggc aaaatatgag gaactatttt ttccgttttt ttctctaata ctcaggtcaa
    34981 aacgctgatt tcacaacctc tgattcacgg tgttccagaa gtagcttcta cggaaataag
    35041 ccgaaatttc acaaaaattt gagaagcaat tttcgtaaat tccttcttat ttcttgaagc
    35101 tgaccacttc tgtcacaacc tcttattttg attagaactt gcgaaaataa accggttaaa
    35161 gtgtgtctag cgcaagagat ttgctataat agacgataag ggtaaaatgt aacgagaagg
    35221 ggttgaaaaa tgtgtatcaa attgtaacag attcttgttg tgatctgcca taccatgtat
    35281 tagcaaaaga aaaagttgat tttttatcaa tgaatctcca attgaatgat caagagttag
    35341 tagatgacct cggaaagaca ttcaattatg accgctacat gaatcagctg aaaaatggtg
    35401 cgatgcctac gacatcacaa atcaatgttg gccgatattt agaatttttc cgttcttatg
    35461 cggaaaaaca gattcctgtt ttatatgtgg ctttttccag tggattaagc ggctcttaca
    35521 gtagtgcgct tcaagcggtt gaattgctga aggaagaata tgaagaccct gagatctatg
    35581 tttttgatac aaaagctgca agtattgggg aagggctttt agtattggaa gctgtaagat
    35641 tgaaaaaaga aggtaaaagc atcgaagaaa ccctagagtg gctggaaagt aattatttga
    35701 aagtccattc atgggtaaca gtagacgatc tgaaatatct agaacgaggc ggtaggattt
    35761 ccaaagcaag tgctactctt ggcagtctat tgagtgtaaa gcctattatt acggtggata
    35821 aagaaggaag gctgacgaat gttgacaaag ttcgaggaag aaacaagtcg atccagacaa
    35881 tcgtcaatga gacggtaaaa acaatcgttg caccacttga tcaaatcgtt tatgtggctt
    35941 acgctgggga tctagagagc gcggagaagg caaaacggct tttggaagag cagataaaga
    36001 tgaaagatgt gaagctttat cccttaggac caacgatcgc cagtcacaca ggctatggct
    36061 gtatcgcgat tttttcgatg ggaatcagtc gataaaagca gtaactcatt ctgtaaaaaa
    36121 gcccagaaat tgattgtaac aaaaacagcg actcttaaaa gatagatgag catcctatct
    36181 cttagaggtc gctgtttttt tattttttaa gctaaatagg ccattatgcc cataactcgt
    36241 tcaattgttt ttgaatatct gcattttcca aaaattcatc atatgtcgta tcagctcgat
    36301 cgatcacacc tttatccgaa acggcaatga tgcggtttgc caatgtttgg ataaattgat
    36361 ggtcatgtga cgcaaataag attgagccag taaatgccat caagccgtca ttcaatgctg
    36421 tgattgattc taagtctaaa tggttcgttg gatcatctaa tacaagtacg ttagctttcg
    36481 aaagcatcat ttttgaaagc atgcaacgga ctttctctcc accagataaa acattcactg
    36541 gtttcaatac ttcttcacca gaaaacaaca ttcttcctaa gaagcttctt aagaaggtgt
    36601 tatcatcttc ttctttactt gcatattgac gcaaccagtc taaaatcgtt agatcagtat
    36661 cgaattcttt cgttgtatcc tttggtaaat aagaattact tgttgtcaca ccccaacgta
    36721 ctgttccagt atctggcgta atttcaccca tgataacttt gaatagcgtt gttgttgtta
    36781 tatcattttc tgcgacgaaa gcgaccttgt cttctttgct caaattaaaa gatatatcat
    36841 ctaaaatttt ctttccatca atcgttacac ttacattttc tacctgcaat aagtcgtttc
    36901 caatctcacg ttcaggtttg aatccaacga atggataacg tctagaagaa ggttggatat
    36961 cgtctaaagt aattttttca agcatttttt tacgtgaagt tgcttgtttt gattttgatg
    37021 cattcgcact aaagcgggca ataaattctt ggagttcttt gatttgttct tcttttttgg
    37081 catttgcgtt tgcttgaagt ttagccgcta gttgactaga ttccaaccaa aaatcataat
    37141 ttcctacata aagtttgatt ttaccaaaat ctagatccgc catatgtgta catactttgt
    37201 tcaaaaagtg acggtcatgg gatacaacga tcacagtatt ttcaaaattg atcaaaaatt
    37261 cttccagcca attgatcgat tggatatcca gaccgtttgt tggttcgtct agcaaaagaa
    37321 catcaggttt accaaatagt gtttgtgcta ataacacttt taccttttgt ccaccagtta
    37381 attcactcat ttgctgatgg tgcaattctt cagggatgtt cagaccttgc agtaaaacag
    37441 ctgcttctgg ttcagcttcc catccattaa gctcagcaaa ttctccttct aattcagctg
    37501 ctcgaatacc atcttcgtca gtgaaatcct ctttcatgta aatcgcatct ttttctttca
    37561 gcacttcata cagacgcttg tgtcccatga tgactgtttc aagtacagta tagtcttcat
    37621 agtcgtaatg gttctgtttc aatacggcca tccgttcatc tggtcccata gtaacggaac
    37681 ctgtggaagg ctgcagatcc cctgataaca ctttaaggaa cgttgattta cctgcaccat
    37741 ttgcaccaat caagccatag cagtttccgg gggtaaattt aatattcaca tcatcaaata
    37801 gtttgcggtc tgaaaagtgc aaactcacat catttacagt aatcaatttt tttcctcact
    37861 tttatcatta ttagttttga caagtcttat agaattatat aggggaaagg taaaagattc
    37921 aaggcaatcg aacattcttt gtgtttcacg tgaaacagaa tgaaaaaaat aaaaataaaa
    37981 gcggagcgaa aatagctact ataggattta ttagtttgca acagcataat ttttgacgtt
    38041 atttataaga gggagtacta taaaactgta aaagaaatga aagaaggatt gaaaatggat
    38101 gaaaaaagaa ccatcgactg gggctcattg attttgggaa ttttatttgt acttgtctca
    38161 ttgttatcat ttcaagaccc tgtcggaaat ttagttgcaa ttgtagtagt ctttgcgatt
    38221 tttgccttta ttaaagggat atttgaactg tttgtacgga acagattaaa agagctaaca
    38281 ggatataaag gaaagatgcc cttaataatc gggatcatcg atattctagt tggcgtcttt
    38341 ttcttattca atattggtgc aggagtcgca gcattgcctt ttgtttttgc agtatggttt
    38401 attgctgatt cagttttagc gttatttact gctgacttgg caagaggagt aagtgaagga
    38461 tattattggt ttacgatcat cgtcaatatt ttaggaattt tattaggaat tttcttattg
    38521 tttaatccaa tttcttctgc gttgacatta agctttttag ttggattcta ttttatgtta
    38581 tttggtatca cacatatcgt ctatgcattt agataagtaa aatcaaacaa ataaaaaagc
    38641 cggcttccga ttacagtttt actgttgtaa ttggaagccg gcttttttat catggacaaa
    38701 tatgcacgag gtgattttta ggtgtcgaga caaatttatg caaaaatgtg agaagctata
    38761 tacacaaatt ttatcttaat actcgaagca tagcgcagtt gtcacaacct cttttcatat
    38821 aattcattca atactggcaa atcatggact tcatattttt ctttgaatgc ttggatttct
    38881 tcttcagaat attttcttgg atctaaatgc agatcttcta ctggcaatgg gcgcttgtta
    38941 ttgatcttca catcgattac tacaggacga tctgattttg cagctgcatc aaaggcaaat
    39001 cgaagttgcg agtattctgt gactgtaaag ctatttgccc cgagcgcttc tccaacttta
    39061 ccgaaatctg catcttctaa aaatacacca aatttctttt gttccgtatc ttcttgttct
    39121 gcttcgatga aaccaaaaga atcattcgaa aagacaacat taataattgg aagctgatat
    39181 ttgacttgtg taatgatatc ttgcatgacc atagcaaacc cgccatcacc acttaaggta
    39241 aatacttgtt tttctgggta gcttagttgt gcggcaattc ctcctggcac accattaccc
    39301 atagttgcga accatccaga tgtcgtatgt ttttgtttac cgttcatatt caataaacga
    39361 atagaatgga tagtcgtgtt accgacatct gtgacgaaaa tcgcatcgtc ttcagcaata
    39421 cgattgattt ctttatagac agcctctgga cgaatcggtt cttcctctcg atcttcaaaa
    39481 gatttcaacc aatttaccca tttttcttta ttttcttgat ttgctaggta ccagctatca
    39541 gcagggcgag catcccctaa ctcgacaagt ctttgcaaag ctgtgtttgc atcaccgagg
    39601 atcgacaaag atgtttcatg gcgtcgtcca aattttgacg catcgatatc gatttggata
    39661 aattcagcag ttggattaaa aaatgcacgt ccaaatggga agtcgctacc gacaaataag
    39721 atcagatcgg cttctgccaa tgcttcattt ccgggtttag tagcgacacg tccagcaaaa
    39781 ccaagaaagt tttcataatc atcaggaata attccttttg ctagaacgga agcgacaaca
    39841 ggaactgaaa aatgttctga gaattctttg atttgcggaa atccgtttcg cgttccttga
    39901 ccaacataaa gaactggttt ttttgctttt tcaagataag gcaaagcagc tagcaaatct
    39961 ttttcttctg gtaatatcac acttgttttg tgagtgtgag cggtggagaa aggttgttcg
    40021 tcaatttctt caaaaccaag atcaacaggg atagtcacga tagccacgcc tttatgctca
    40081 taggcggctt taatggcttc atctactaca tgcggaagac tttgtggtgt catgactgta
    40141 cgattgtata cgctaacatc tgcgaaaata ggattttcat ttagttcctg gaaagagtta
    40201 tagttcatgg atgtagaagc aacttgtcct aagaacgcta ctagaggcac atggtccatc
    40261 tgtgcatcat acaaaccatt gatcaaatgt gtcgcaccag gtcctgcaga gccgaagaca
    40321 gcgccgactt tccccgttaa ttttgcatct gcagcggctg cgagtgcgcc gacttcttca
    40381 tgacgaactt gaatgtagtt gatttcggtt ttttcttgat atagcgcatc cataattgaa
    40441 ttgaaagatc ctccgggaat gccgtaaata tggtcgatac cccagctttc aagaactttt
    40501 accattgcga ttcctgcatt gatttttgac atggtgtttc actcctttag caatgatgat
    40561 acataaattt tttgtatcta gagtatagaa ctttttatcg aaaatcccaa ctaattcgtc
    40621 ttttcacaaa aatgtagtca tgtttttggg aatatgctag agtagtacat agatagattc
    40681 aagagagggg aatggcatgg ttgaatggct attgagactt gaaccttggc agcaagcact
    40741 tgctgggaca gcttttactt attttatgac agctcttggt gccgggttgg tttttttctt
    40801 taaagaaatc aaaaaagaag tgctaaactt gatgttagga tttgcttctg gtgtcatgat
    40861 tgctgcaagt ttttggtctt tgttagatcc ggctattaca aaagcagaag aaaatggaga
    40921 tattgcttgg ctagttgtaa gtattgggtt tggtttaggc ggtgtgtttt tatatatggc
    40981 agataaaaca ctgccccata tgcattttgg accacaacat gaagcagaag gattgcctac
    41041 ccatttaaaa cggacgatct tgcttgtttt ttctattaca ttgcataaca ttcctgaagg
    41101 tttagccgtg ggggtagcat tcggtgcagc agcaactgcg gataatccga cagccgctat
    41161 attagccgct gtttcggtgg cgctaggtat tggtatccaa aacttcccag aaggagcagc
    41221 tgtatcaatc ccgttgcgac aagaaggtct gagtcgtaaa aaggcctttg tttacggaca
    41281 agcttctgga atcgttgaac caattgctgg agtgattgga gcgctactag taacgaaagt
    41341 ggagctgctg cttccttatg cacttgcttt tgccgcagga gcaatgattt atgtcgtggt
    41401 ggaagaattg atccctgaag cacagcagac attgtccagc aaacgtcatt ttgcagtttt
    41461 tggcgtcatg agtggattta tcattatgat gattttggat gtggcattag gataaataaa
    41521 aaaaatatat atgatatatc aaatagggcc gcgaacttat atcgcgaccc tattttttta
    41581 gtaagttata tcataatgaa gtgaatggta tcatacatta ataatagttt tttctatgtg
    41641 tatttccttt gatccagcga acaagccaga tgataagtgc gattgggatt agaactttga
    41701 ccgcaaacca taaaagcccg cttaggacac tgacaaaaag actgatgacg aagctagctg
    41761 caattagcac taaaagaacc atgaagatat ttaagaacat atttttttga cgcatacaaa
    41821 accctcctct tgttcattct ttactataga aaaagtataa cagggattgt ttaaaaacac
    41881 ctccaactga agactgattt ttacttcatc tacttaaatg atcaaacaat tgctttttct
    41941 ctggtttatc atctaaaata gagcggaaaa ggaggagaat atcatgccta aaaatcgtct
    42001 tgaagcattt acagatgctg taatcgcgat tatcatgact attttagttt tagaacttca
    42061 tgaacctaac ggagacacgt gggaggcgct cgctgcatta ggttaccgat tttttatcta
    42121 tattgtcagt tttatcattt tagcgattta ttggaacaat catcatcatt tatttcaagt
    42181 tgtacataag ataaatggac gggtcttatg ggcgaacagt ttctttgttt ttgcgctttc
    42241 gctttttccg tttgcaactt catggatcag tgagtacatc aatagcctgg ctccagaaat
    42301 gacttatggt tttgttacct tgaccgctaa tattgcgtat tatatcttgg caaaagaact
    42361 tgtcaaagca aataaaggcc acgagaaagc attgaaggcg atgttgaata attacaagaa
    42421 atcgtatcta tcgattggtt tgaatgtgtt aggaattgtc ttagggtatt tagtagcgcc
    42481 agtagccgtg ctgatcgcaa acatcgtgat tctagctgct tggatcatcc caagtcgtac
    42541 catcgaatca caatatcggt aaaatgatcc gtgtttaaaa tttaagagaa aaatatagaa
    42601 aaaataaata aacgatcaaa tatccgagtg atactagtat tcaaagaggg atgcagatgg
    42661 atcaaaaaag aattcatgta ggactgatta ctagttttgt cacgatgctt atttatttgg
    42721 atcaaggtca tttgacttgg acagtagttg gtgtcgtagg atttttgaca ttattcacag
    42781 caataaaaaa ataaacatct ttatgtaatc tgatgttcta tctatttaag aaaagcatgt
    42841 ttacagcagt atgattctgt tgtaaacgtg tttttatttg tggaaaattt aatttttaga
    42901 aaagtgtatc gaaaaataga tagttagttt ttccacagtg gataacttcg taagagataa
    42961 aaataaaaaa ttagtcaaag aagggcgtat agatttcttt tgataggaga tatacaacag
    43021 aaatgaataa atattaacgt gttttcaaac agtataaaac ggtgtggttt ttggaataaa
    43081 aaaataacat atctcatttt acgcttttgt tattttatac ttaaaaaata acgacacaga
    43141 aaataccgtg tctcagattt ctctactact tctaaaaact actgtttttt tcctttgaaa
    43201 tgccttcaaa aagtaggatc aggcagaata tactggcaga atcaaggaga agggagccta
    43261 aataaggaga aaaaccatag aaaatataaa gtaattactt ataaaacaag ctttttatag
    43321 aaaaataata tacctgagta gggtataaat taagacggaa ttcctttcta gattgagata
    43381 ttgactagga agaatgttaa gattttaagc ctttaagcta aaaaaaaacc ctttttgtta
    43441 aataagggga atatagcctg tcagtttcaa actgcaagtc gtcctgctgc aataatatag
    43501 tagattagag atgaaaatag atttttttaa accaatgact gaataaaaag accgtcatag
    43561 atacacattg gaatgtgtct attacggtct ttttttacga acgattttat tgaagacgga
    43621 cagttcgggt caaaaataaa aaagctacga tcagaaataa gaataaaatg tatcccaaaa
    43681 taatggctag acggtctaac ttatttgtcg atagatgttt gtttagaagt tgataggccc
    43741 ataaacctat cagtcctcct gttgtattag ttatcaaatc agtgatgtcc gctacgccaa
    43801 taccgaatag gaattgaatc aattctgcca agaagcttac aaggaaaata atccctaatt
    43861 ttttagaaaa agaaagtctc ttgaaattga cattcaaaag caccccaaaa ggaaaaaaga
    43921 caatcaagtt ataagtggtc tcacgtaata ccgtcgtatt ttcaaaagaa aaagtagaaa
    43981 aagggacgag attgacattg ctgtaagaat aagtgagaaa ttgtggaaga ttaaatgata
    44041 gcttgaataa aatcaaccat aatagaaaga ataaataaat ccctaataaa aattttgata
    44101 cataccgcat agacatctcc tccatttaaa aagtatacca tcgaaaaccg ctgaaaaatc
    44161 ataaaaaagt atgaagttta aggaccaacg tagttatcgt acgaaaatta gaagcttttt
    44221 tttgttggga atccggtttc tttaacaaag ctaagatagc gagttgcttg gaaaagttgc
    44281 tatctttttt ctgtcaaaac gactcggaat gttcgttttt tgttctaatt tctccaagtt
    44341 gtttactttt tgatactaag tttatgaaaa atcaagaaat agttgttata ctaggtaatg
    44401 ctgacaaacg ggattggcat ttcatcttgg ttcagctttt tttccaatta ctaggaagga
    44461 gggatagatt gttcaagact tattttcgtt tcaataaaat acaagataat ccttttcgta
    44521 tcatgaatct gatgctactt atctttattg tattatggtt aggttacata aatcatgatt
    44581 ttttgatttc aagtttttca tcattaggga tctttacttt tttctattat caaaacatac
    44641 cgatgaaata tttgctgaaa cgtatgtttc tgatcggttg cggactgttg gttgctttcg
    44701 ttttggggat cttatcgact tatgttttat ggcttgaacc atttgccgta gctttggttg
    44761 ctttttccag cagattcgtg ttgcgattat tccatatttc taaaccaggt ggcttgtttt
    44821 ttgcgatgct ttctgccatg ggaacgagca tgcagctgcc aatcgctcaa ttaccgatcg
    44881 tctcacttta tttttttatg ggtgtcgttt ttgccctgat tgcggcagtg attacaaaat
    44941 tactggattc acggcctgag cagacaattg aaaaagcaac tttaaaagaa agatttcacg
    45001 aagagccttt agtgatcatt gattctgttt tctacagcgc tgccttattt ctttccgttt
    45061 atgtcagtca cggcttgaat ctgcataatc cttattggtt gaccttgtca tgtgcatcga
    45121 ttttgctagc agaaaacttg gatgcgatga agcatcgaca agtccaatat ctgattggat
    45181 cgatgggtgg gttatgtgtg tcggcattct tgtcatttgt gccgtttacg cagttgcaga
    45241 ccatttttct gatcactttt ctatatggaa tcgcacaatt tctagttgct agaaattatg
    45301 cagttgctaa tatttttctt aatccgatgg cgttgatgct atctacactt attcgtggag
    45361 catacttgat ttctttgatc gaatatcgtt ttttagggat cgtcatagga agtttcatcg
    45421 gtttaggtgt tgcgtgggta atgacggttg gtttgcaaca ttatttaacg gttgttcgtc
    45481 aaaaattaga atagaaggac aaatatatgt gccaaaagag gttatgacaa gatttttgtc
    45541 acaacctcta attcaaggtg ttcaaaagcc agattctcag cattaagtca aattcacaca
    45601 aaaatgtgga aaggaacttt caaaaaaatt ttatatttat tctatcaaaa aattttatat
    45661 ttattctatc aaaaaatttt gtttatgatg gtaactgaat aaactttcct gagatggtca
    45721 atgctttcct tgaaagtctt acagatattc tttcttcata gaaagtttaa gttttatagt
    45781 tagtgtacaa taaaagtatg tttataccat atggtgtccg gataatcagt catttaaaca
    45841 atgaggttca aagatatgaa aaggggaaat ttgatgaaga aaataagcaa tgaaatccaa
    45901 attctggcag aaactttaac tcttcccaaa gtcgttatag agcaaatgat tgtacaagca
    45961 aaaaacatcc ttgatgaggt gtttgagcaa tatagtcatg aactaatgga tcctaataaa
    46021 gcaaaggcga ctgcaaagaa aatagacaaa gtctatgaag aggaaccttt tgcagcatta
    46081 gctatttatc tatatgcagc ttctcaaagt tggaaaaaaa tttatcaacc attgaagatt
    46141 ccaagaacta tctatttggc aacaatgaat gcttttacta gatttattca tgaacatttc
    46201 caagtaacag gaagctatcg ctttgaccgt ggtttttgga tttggcatta cactagtggc
    46261 ttgatctttc ggattggtga attggagtac gaaatgacat attttccgaa agggtacacg
    46321 gatctaagat tagaaggaaa gcagtgcctt tctcttcata ttccttccga tgcagattta
    46381 tctcagaata agataagaga tagttacgaa agtgccattc gtttttttga actttatttt
    46441 cctgattacc attaccaagt gatgtacaca gatacttggt tactatcacc caatcttact
    46501 aaatggttga aaaaagagtc aaaaatctgt ctttttgcag ccgattatcg attattatca
    46561 gttgatgaac aggacgatag tggagtccct tggatctttg gacgagtaga tgcccaaata
    46621 catgattatc cagaaagtac gagtttacag cgacaagcaa aagagcaatt gcttgcaggc
    46681 gagcacattg gctctggctt aggtattctt acttcataag tttagtactt cgaaatagtt
    46741 taaaagagcg tgagacaaaa gtaaagaaca cttttgtctc acgctctaaa cacgtataaa
    46801 cggcggaagc agaagcaact ccttcggaaa taagctgaaa ttcacaaaaa tttgaaaagc
    46861 aattttcgtg aatttcttct tatttcttgg agttaaacgc ttctgtccca gcctcttttt
    46921 tagtgttcta tcgaacacac agtacgttca ataggtaaac tagctataac aatagatatt
    46981 aaagttaacg gacaagaggg ccttttttag gtagctaaaa cgtaataatg aaaatttatt
    47041 tccagagata ggagtcaatc agctagtctg atcgactgtt ttaacaagtt gactttcatt
    47101 ttaacttttg ataccattta aaacacaaat cgtaattgtt tcgatttgtg ttttttagca
    47161 tgactacaat caaagaagaa agtgggtcgt ccatatggaa aaaacagata tctcaagtgc
    47221 ataccgccgc ttgaaaagcc caaatatcaa aacacgaaaa cgtgcgctga agatcatcaa
    47281 agatgtgaaa cggaatagtg ggaaaaggta agaagaagga aacttaatta aaaaaatagc
    47341 cgaaaaacgt ttttcggcta ttttcaataa tcggtttttg tgtaaggttt ccgaaagaac
    47401 tgctgttgat tttccatttt taacatatga taaattggta gaatctttct tttcaaattg
    47461 ataccattcc ctaattccag ttatatagtt aactacagaa ccacaaagca cgtacgttta
    47521 taaaagtatt atctgtagtt atttttcaat tccctttcaa cctcttattt tgaccagtag
    47581 tattgatcac tttacctttt aacacctttg ttcgtttttg aaacattttt agtcaagaat
    47641 ggaaacgtaa ctacataatc aaaggttttg cgaaatattt catgaaatat ttcatgtaga
    47701 agcgagcaat acggttgcaa ataaccatta tcgtttaata agcagttacg aaagctccca
    47761 atatctctaa cgttcagctc actccatttc ttttcttcaa aaaaatcagt gattcgtatc
    47821 tctttctatt tgtcgaaaaa gttaacttta aaaagtaacg ccgaaaaaat atgcaaaaaa
    47881 ataaaaaagc agttactatt gctagaataa catcaaggaa taataagttt tggttttcag
    47941 ataatagtcg ataagttgtg tattggaatt ttagatacag taataaagta tttttcatga
    48001 aattttgtga gaatcactat tacaagtatc tttaataaaa ttaatggtta aggaggaact
    48061 taaagtagaa tgtaaatgaa tagttgtagt cagtcgattg tgatactaga ctcaaagttg
    48121 caggaataag tttttcaatt tgtgattgga agataaaaaa tgaaaaagaa gggctttttt
    48181 ttatactttg ttgattgtag tgtttatttt ccctctgttt agccaagtaa cattttctat
    48241 gactcaacca gtttcaagtg aggaacatga taaccttttt cgtgctacag aagagtttaa
    48301 gaaatatcag gaaaatattg ttccggagac tccattagct agtgagccaa ttactgatat
    48361 tgatggaaac caaataggat ggtatataca gtacgaagtt atggtggtaa ataatgactc
    48421 aatagtaaaa aatacagtag gcttagagct aacaccgatt gaaaaggtga gttcattgtt
    48481 aacgtatatt tatactgatg aaagtgacga gactgagatc attttaacgg attactcaaa
    48541 aattgctact gataaaaagt atatattgtg gatgtagaca ctagtgaaat actttatgat
    48601 atagaaattg atgaaaattt actagatgta gcacaagaaa tcgatcatca aaagcaggaa
    48661 gctattcgat atgctggtag aaaagggaaa agaaaatatt tattacgtga atgtagcaaa
    48721 agttagagaa gatgaaaatg agtggaaaga attcaagagt cgctactcaa ttaactcgac
    48781 tccgacattt acagtttaca gagaaggatc gatagaaaaa actgtttttt ggactaaaga
    48841 aagtggaatg tctttagctg aagtagaaga gtttttggat tatgttagta tgcaacagta
    48901 agggagttct tattatgaaa aattttgaca catattatgt tattgttttt tcgatatctt
    48961 tgctgttaat attactaact ttaatgcagt ataaagagta tccagagtat tttattttaa
    49021 cttttgtata tttagtaagt agctacacac ttctatataa attcagaagt tcttctagag
    49081 tttctaaagt ttgtttctta attagcttat tgattctata atatttttga tttatatagg
    49141 aaattaaaaa tattatagaa tcaacactca gagaacgggt tggtttttaa tagatttaat
    49201 aagtactgat aatgaaattt ctcctggttg ggaaaacgaa gttggttacc ctgtagaaga
    49261 attttttcaa gattactttg cggagtatgc cgataggata atgagagatt acgtaacaga
    49321 taaaactcaa gaagtcatca atcaatccca gtcattaaat gaattatctg ataaggcgaa
    49381 agaagaagca gttgccatta tttcttcagg gattagtgac tatattgata tgagtggtga
    49441 aatcaattat ggcgataaag acaaaattgt acgcatgata aaagctttta tcaaaacttt
    49501 tgatgtgaag gcagatctta agtttaatga tacttaccta gtaggaaaat taattaatat
    49561 ccttgggaca gagaaagata cggaaacgtt tatttcctct ttgtctatgt tgtttacaga
    49621 taagcatttt tcaactcagc ttggtggaga ggaactagtg gaaatctttt aaccattacg
    49681 cccagcatta ataaaagtat atcaaaaaag tactcctgat gatttttaag attggtttga
    49741 gaaataatgt gaaaacacta tttttaatgt taattataga tagagatgaa cgcgtcatat
    49801 ggttaaaaga atgaaaaagt caaagataca ctgctatatt tcactaagga tatagcagtg
    49861 tatctttcat gtcgtttcac tggcagtttt ttataaaagg aggtgtgcat ttcagttgct
    49921 tttctttggt agttagttga atcgtttaag aattaacgga tgtggcagac aggtgctctg
    49981 tccaaaaacc agtaaaatct ttgatggttc catctttatt tagctgtgcc tgttcaaata
    50041 ctgttttgtt tttaccgaat ggatcaattg caataattgt tccgatcccc gcacgtttgg
    50101 cagcaagtaa tcctgagtaa gcatcttcga taacaagaca atcagccgga gctaagctca
    50161 gtttgtctgc cgctttaaga aaaatatccg gttgcggttt cccagggaaa gagccgtcgt
    50221 catagacaat cttgtcccag tcaaaccagc gggctaaatc gaaaatatca aaataaaaag
    50281 caacattctc tttgacagta gccgtggcaa tcgttaatgg aatctgttgg tcagtcagct
    50341 ggtcaagagt cgcttcaagc ccttttgtca actgaagctc gttttcattt tgcaagcaaa
    50401 gcatacgata atagctttct ttttcttctg acaatacggc gatctcagag gcggtcaaat
    50461 gctctgaaat gaaatgtttc aaaatctccg tattcgtccg accatgaata ttttttaaaa
    50521 tatcctcgtc tgataaacca tcttttgtat gatcatgtat catatgcagc caagcagctt
    50581 catgcagatg agagtccaaa aacattgttc cgttgaaatc aaatataatc cctttcatag
    50641 ttacgctcct atagtggtat tttcggttga atcagcaatt tgcagatcga catattgtgc
    50701 atagtgctct tgaacctccc gcgagatctg gcgatccgta atgagcagat cgaaatcatg
    50761 caaattataa aacacataaa aatcatctcg attgaatttt ttattatcaa cgagtagata
    50821 tttcttacgg gaattattta gagcgatctg ctgtgcttct ccttcttcgg tactgtaagt
    50881 agagatcgct tcgttgtgaa cgccatttga actgataaat gcttttgtaa actttagtct
    50941 tcttaaattg tcgttggtga tcggtccgac aaatgcgccg gtatttttcc ggaaatcacc
    51001 gccaatcagt agaatttctg gtccatctgc ttgagcaaga atatcaaaaa ctggataatt
    51061 atttgtaatg atccgaattt tcttgttcag taaatgcgtc gccaatagtt cgattgttgt
    51121 acctggtcct aagaaaatcg tttctccctc gtgaatcaag gaggctgctg tggcagcaat
    51181 ttcttttttt tcttgaatct gcagagtggc tttttcagtg tgagaaagtt cttgatctaa
    51241 agtgtaggaa agactttgag cccctccatg gacacgcagc agcttgcccg atttttctaa
    51301 ttcatctaaa tctctgcgaa cggtcatatc agaaacatct aattgattga tgatttcatt
    51361 aacggtaagg attccttttt tattgaccat ttctacgata gtaagcaatc tttctttttt
    51421 caacattgtc ttcacctcta atttaaggat aatctatcat ataaacggac aacagtcaat
    51481 ctaattcgaa caaaagtaaa catttagggt ggtttttatg tttgttacaa tagattttat
    51541 tgctgttttc tggtttttat gattatttgt gtttgttttt gttgacaaat gttttggatg
    51601 cgtttacaat gcaatcagtt agaaagagcg aaaactgatt atagatttga ggagagatgt
    51661 acatgcttaa attaccagaa gattttattt ttggcggagc cacagcagcc tatcaggttg
    51721 aaggagccac taaggaaggt ggcaaaggcg ctgttgcttg ggatgacttt ttagaggaac
    51781 aagggcgatt cagtcccgat ccggcaagtg atttttatca tcaatatgca aaggacattg
    51841 aattgtgtga acgttttggt gtaaatggtc taagattatc cattgcttgg agccgcattt
    51901 ttcctgatgg agctgggaaa ccaaatccag aaggaatcgc tttttatcat cgtgtgttcg
    51961 aagaatgtaa gaaaagaaac gtaacgccgt ttgtgacgtt gcatcatttt gataccccta
    52021 aacgtttgtt tgaccatgga gattttttga atcgagaaac aatagaagca tttgtttcct
    52081 atgccatttt ttgttttcat gaattcaaag aagtcaaggt gtggagtacc tttaatgaaa
    52141 tctatccagt tgcaaccaat caatatttgt taggtgtttt cccaccagga atcaaatatg
    52201 attttacaaa gatcgtcgcc tgtcttcata atatgatggt tgctcatgcc cgtgtagtga
    52261 actatttcaa agaaaacgaa cttccgggtg aaattggtgt agttcactca ttagagacga
    52321 aatatgcggc aacagacgcg ccggaagata agcatgctgc ctttttagac gatgcattgt
    52381 cgatccgttt cttattagat gctacctatt taggctatta ttcaactgaa accttgactg
    52441 ctcttgatga gatatgtgaa gcaaatcagg ccagctatca ttttcctgaa gaagatttcg
    52501 ttgaattgaa aaaagcatcc acgcgtaatg actacttagg gatcaatcac taccaatgcc
    52561 attttgtcaa agcttacgat ggagaaaatg caatccatca taacggtacg ggtgaaaaag
    52621 ggacctctgt ttataaagtg aagggaatcg gagaacgtat ttataaagaa ggaattcctc
    52681 gaactgattg ggactggctg atttatccag aaggtctata tgacttgttg ctgcgaatta
    52741 aaagcgatta cccacattac aacaaaatct atatcactga gaacgggatg gggtataaag
    52801 atcagtttga agatggcatt attatggatc agccgagaat cgactatttg agagtctatt
    52861 tggaatcctt aagcaaggcg ataacagccg gggtaaatgt gaaggggtat tttttgtggt
    52921 cgcttatgga tcttttctca tggacaaatg ggtataacaa aaggtatggc ttgttttatg
    52981 ttgattttga aacccagaag cgttacccaa aagaatcagc ttactggtac aagttggtca
    53041 gtgaaaccaa aacgattatt taataagtga taatggagga agaaaagatg aataaagagg
    53101 aattacaaat gcttggtttt gagatcgttg catattcagg cgacgctcgc agtacattat
    53161 tgaaattatt gaaagaagta agacaaggaa actttgaaca tgttgattcg gcgttgaaag
    53221 aagccgacga aaatttaacc cttgcacata attcgcaaac aaaaatttta gcggaagaag
    53281 catctgggaa agagatggag atgggattca tttttatcca tgggcaggat catttaatga
    53341 ccactttatt gctgagagat ctgattcaag actttattgt actgtacaga cagaatcaag
    53401 gataggagaa gaacgctatg gatggaatca ttaaacaaat cgaaaaaggg aaaccatttt
    53461 ttgaaaaaat ctcacgtaat agttatttag gagccgttcg tgacggattt ttaacagcga
    53521 tgccagctat tttattttca agcattttca ttttgattgc tgcggttcct gagatttttg
    53581 gttaccaatg gcctgaatct gtctccacat ggctatggaa agtctataat tattcgatgg
    53641 gtgttgtagg gttactcgtt tcagcaacca ctgctcgctg cttggctgat tcgatgaatc
    53701 gtcgcttacc gaaaaacaaa gtaatcaaca ccacctctgt gatgctggcc tctgtggtaa
    53761 gtttcctgtt gttaagcgtc tctccgattg aaggtggatt ttcaacggaa tatatgggga
    53821 caaagggact actggcttcc tttgtcgctg catttttaac agttaattta tataagtttt
    53881 gtgtgctgaa agatattacc attaaaatgc ctaaagaagt tcctggaacg atttcgcaaa
    53941 ccttccgaga tatttttcct ttctcttttt cagtatttgc ggccgtttta attgatttag
    54001 gcattcgaca aatcttccaa atctcatttg cagaagcaat cattacggtg ctgcagccgc
    54061 tatttacagc agctgacggg tacttaggaa tcgctattat ctggggagcg atggcgctgt
    54121 tttggtttgt cggtgttcat ggaccgtcga tcgtggagcc ggcaattgcg gcaattatct
    54181 atgccaatgt ggaaaccaat ctgcaattgt tcaattccgg tgaacaagct tctaaagtac
    54241 tgacggtggg tttagggaat tttgtaggaa ctatgggagg aactggggca acattggttg
    54301 ttccttttat cttcctactc tttgctaagt ctaagcagtt gaaggcagtt gggaaagctt
    54361 cctttattcc agtaagtttc gctgtcaacg aaccattgct atttgcggca cccatgattt
    54421 tgaaccctta tttttttatt ccatttttgt taacacctgt tgtaaacgtt tgcctgttca
    54481 agttttttgt cgatgtattg ggcatgaaca gctttatgta cgttttgcct tgggcaactc
    54541 cagcaccgat cggtttggtt ctaggaacgg gcatgggtat cttagctttt gttctagcag
    54601 cggttctaat cgtcgttgac ttcctgatct atctaccatt ttgcaaagca tacgatgctg
    54661 tcttagtaga gaaagaagca caaaaagcag aggtgatcgc aaccgaggaa ggtgcttctg
    54721 ccgatgtacg tgaggaagta cctgtggcag cgagtcaagt tatcagcgat gcaaataaag
    54781 aaatcaatgt gttggtactt tgtgctggcg cagggacaag tgcgatgtta gctaatgctt
    54841 taaaaaaagg tgcatctgaa tcgaaagcac cgatcagtgc aatggcgggt gcttatggtt
    54901 ctcattacga aatgctgcag gattttgata tggtggtctt agcaccgcaa gtcaattctt
    54961 actatgatga tatcaaagaa gacaccgatc gcttaggaat caagctggtt gcgacaaaag
    55021 gagcagaata tatcggatta acgagagatc ctgaaaaagc tgttcagttt attctgaacc
    55081 aatttcaata aaggaggagc cataatgaaa atgggaattt ggttgcgtaa agctgtttta
    55141 tttgcagctg tgttaggggc tttgggggct gtttcaaaaa ctgttgaagc atctgccagc
    55201 gaatttattc gcggagcaga tatttcgatc ctgtcagata tggaaaaatc tggtgcaaaa
    55261 tattatgaag acgatatttc aaaagatgcc ttagagattt taaaaaataa tggtgtcaac
    55321 tatgttcgac tgcgtttgtg gcaggatcct tataatagta atggagaaag ttatggagca
    55381 gggacaaatg atctggaaac gacgattgac cttgcaaaac gagcaaaaaa tctgggactt
    55441 aaggtgctgc tggattttca ctacagtgat ttttgggttg atcctgggaa acagaatctt
    55501 cctaaagcat ggcaaggtct gacctttgaa gaaatgaata cggcattgta cgactataca
    55561 aagaacgttc tgtcggaaat gaagcagctg gacgtttatc ctgatatggt tcagatcggc
    55621 aatgaactga atagcggaat gctctggcct tatggcaagt cttggggaga aggcggggga
    55681 gaatttgatc gattggctgc ttttttgaag tctggtatcc aagctgttcg agacactcaa
    55741 cctaaaacaa ctccagtaat gctccactta gctgatggtg gcgatacagg agcatttact
    55801 tggtggtttg atgaaatcac gagtcgaggt gtgtcatttg atttaattgg agtgtcgtat
    55861 tatccgtatt ggcacggttc aatgaatgaa cttcaaacca atatgaatgc gatcagccaa
    55921 cggtatggta aagaagtgat cgtagttgaa acagcttatg ggcatacaac agcgaatgcc
    55981 gatactatgc caaatgcttt tggtgaagcc gaagcagctg cggggggata tgaaccaaca
    56041 ccgacaggac aagcagagta tttgctggat cttgccgatc ggattcaggc agtaccgaat
    56101 aatcgcgggg cgggcttctt ctattgggaa cctctttggt acaacggaaa tgtgagttgg
    56161 gcaacacaag caggtatgaa ttatctcagt gttcaatcca ctatgggaaa cgaatgggac
    56221 aaccaagcga tgtttgattt tgctggaaac gccttgccaa gcttgcgtgc gtttaaacaa
    56281 gcaggggcgc aaataaatct agttaaaaat gcaagtttcg aaagcgatgg accaacgacc
    56341 agtccttcca attggcaaac ctggtttcaa caaggaaccg ctaagggtac gatcaaaacg
    56401 gaagcgggca ctttttttgg ggactacaaa ctaacttttt ggcaggatca agcatacgag
    56461 gcatcagctt atcaaaatgt tagtggcata agcaaaggaa cttacacatt gagtgcctat
    56521 gtaatgtctg ggggagagtt tgatactaat cagttatata tcaaaaatta tggtggagcg
    56581 gaactaaata ctgcggttgt taaaacaagt gaatggacaa aaattacaat caaagacatt
    56641 ccaattacaa caggtgtttg tgaaattggg gtttatagca aggcttcagg aaatgcttgg
    56701 acgaacgttg attttgtttc attggtgaaa caatagactg cggatcgttt cgattcaaga
    56761 tcggaggttc ccttcagcca catcgttagc gtagaaggca ggaatcgaac ctgcacctcg
    56821 cctttgccaa aaataaccag aaacgatttc cagtcatttt taccaaaacg agtaaagcac
    56881 cagacttcat ctacactttg tattatgcta aagagagttc aacgatttcg taagaagcaa
    56941 tgaaaaaatt gcaaaaagtt gtgcagataa cataaagttt gtttaagaaa gggtaacctt
    57001 agaattccgt cgtgaatatg atttgagcac ttagatggat agaaaaaagt tctcggaaaa
    57061 cagttcgttt ttcgagaact tctttttatg ataagaatga aacaaattaa cttatattat
    57121 agtctctttt ggtagggaac catcttattt ttaatgaaaa tcaagcattt tagctattga
    57181 agaatgttga tttataggga ttccccctcc atattatgtt ggctctttat tcccactctg
    57241 ttttcaacgt aaagtgtata aaacagaatg cgatactatc aagggagtta aaacaatata
    57301 cagaacagta aaacactata aataaaaata aaagtgcaat aaaagtgcaa tttttgcacc
    57361 taatcatact ctgtttatat atgaaaacta gattctgaat ccaatatttg gttaacgaga
    57421 ggcgttcgaa tttgaacgtc ttttatatat tactttcaaa taaatatgag gtagaatact
    57481 atctattttc tttttaaccc aattgttata atggagagtg taaaatattt tgtgtaaata
    57541 gaaaaaagga agtcccttct gtagaataga gttaccacaa cacattcaca gaagagagga
    57601 cttccctatg aacgatttta ctacagaaat tctaaagact ctagcgaaca aaggcgattt
    57661 gaatgaatta ttccgtgtcc atttggagaa agcagtcaat acgcttctca aaacggagtt
    57721 aacggctttc ctagattacg aaaagtatga tcgcattggt tttaacacgg gtaattctcg
    57781 taacggctcc tatgaccgta cggtcaagac cgagtatggg gaacttcatc tccagattcc
    57841 gcgcgaccgc aatggtgagt tcaagcaaca gactgttcct gcttatagac ggacgaatga
    57901 cacgttagag gagaccgtca ttcacctctt ccgaaaaggt attaccatgt cggaaatcgc
    57961 agacttgatt gagaaaatgt atgggcatta ctacacgccc caaaccatgt ccaatataac
    58021 aaaatcattt acagaagagg taacggcgtt taatgggcgg gagcttcatg accgttatgc
    58081 tgctatttat atggacgcaa cgtatattcc gttaaagcgg aaaaccgtcg ccaaggaagc
    58141 tattcatatc gcagttggca ttcgcccgga cggatcaaag gaagtattga gctatgcgat
    58201 tgcaccgact gaatccatca cgatttggga ggaaatttta ttggaccttc aagagcgcgg
    58261 tttgaaaaat gtcctcctgt tcatcacgga tggcttaaag gggatggtag gagcgattag
    58321 tcggttctat cccaaagctc gttttcaaca ttgttgtgta cacgtttccc gtaatatcag
    58381 tcataaagtg cgtgtcgatg atcgtaagga agtctgtgat gattttaaaa tggtgtatca
    58441 agcctcatct aaagaggtgg cgttggaagc acgtggtact tttgcggaaa aatggaaaac
    58501 cagctatcca aaagtggttg aatcgattct ttcgaacgat cacttgctca ctttctatga
    58561 tttccccttg gccatacgca agagtattta ttctacgaac ttgattgaat cctttaataa
    58621 acaaatcaag aaatacagcc accgcaagga acagttccaa aatgaagagt cgatggaacg
    58681 tttcttagtc tcgtcttttg atacttacaa ccaaaaattc ctaggtcgca gtcataaagg
    58741 tttccaacag gccgaaggcg agctcgaaca aatgctaagc caactgattg agaattagaa
    58801 acaatctgca gtagggaaga atcatttaca caaaattatt gacgctccct tataatgaga
    58861 acttttacta acataattta tgataaactt actatataat catattaatt aaatagttag
    58921 gagatctgct tatgtttata tctactcttc aaattcgaaa ttttagaaat tatgaatccg
    58981 aaatctttcg attcgataat gagacaaata ctattatagg tgagaatgat tcagggaaaa
    59041 ccaatgctct tactgcattg agaatcttat tagatgatag ttattactat agtagtaaaa
    59101 cactaaaaga atcagatttt tttcatggaa ttcaaaatgg gtggcaaggg cattggatta
    59161 ttatctctgc gacatttgaa ggaatcagcg aagaagaatt tgacaatgag atttgtgctt
    59221 ccatttcttt aaattctgaa agtcaaacaa tcttagaaga attgatttca aatgcagata
    59281 aaggtgtagg tagtatttct ctatttatta gacctaacaa agctattaga aagcaattat
    59341 ttgatatttc cactgaatta gactctcatc aatttaacga atttagaaat tctattcgtc
    59401 tatccgacta tgaattttac tacacatcta aatcaaatct aaatttctgt atcaatgaaa
    59461 attatgataa attggtagga agactcaatg acaatatagc tagtaatcct gaagaagacg
    59521 atgaagctct gttgggctca agaattgaca tgtcagatat tttcaagcat atttcggttg
    59581 tttatgttga cgctcttcga gatgttctta gagaaatgaa aaacaatcga aacccagtca
    59641 aaagaatcat ggaaacaatt gaatcaaaaa tatcatcaga taatgttgag tcattaaaaa
    59701 caattataca gcaattaaat gagactatta ccagtgttcc tgaaattagg aaaattggcg
    59761 aaaatattaa tcggcaacta aatagcataa ttggttcagt gtattctcct aatcttcttc
    59821 tttcctcaac tatgtcagat gatatgggtt ctttagcaaa atttctttca atgaagccag
    59881 aacaaaatat cgacttagac ttactagggt taggacatct aaatatgatt tatttagctt
    59941 tgaaaatagt cgaatttgaa gcgtgtcgtt caagagaact acttaatatt atgttgattg
    60001 aagaaccaga agctcatatt catcatcata ttcaaaaaac tctgttcgaa ggattaaatc
    60061 ttcaaaaaaa ctatactcag attctcatga ccacacattc tgtacattta gctgaagtgt
    60121 ctgaaatatc tcggatgaat gtattaaaat cgtttaatgg caaatctatc gttatgaatc
    60181 cagcaaataa tctgaactca tttgctaaag aaaagttaaa aaagaacaat ctaaatctaa
    60241 taaacgcagt agagagatat ttagatgtta aaagaaatgg attgcttttt tctaaaggtg
    60301 ttatcttagt tgaaggagat gctgaagaaa tacttattcc tcaaatagta aaaaaattat
    60361 ttggtataaa cttagacgaa cttggaatag gtttgattaa tgttggtagt acttcgtttg
    60421 aatatatcgc tagcttgttt gacgatgata gaatacagag aaagtgtgct attgtaactg
    60481 atttagatga acaggcaatc ccatcagaac atcgattgta taaaagcact gcacaagaga
    60541 aaggtcaagc aagaaaagaa aaattatcct ccctttttaa tgaaaacaat tgggttaatt
    60601 gtttttatgc taatacaaca tttgaaattg agtttttaga tgtgaataaa gaaaatattc
    60661 taacttatgt cagtccaatt atagatgacg cattcaaaga taaaaaaaca ataactgctt
    60721 ataaagaaga aatacaaagt gaacaatatt tagaaagaaa tttagcgatg ttaaaactag
    60781 ccaatcatgt tggtaagggg tggtttgcaa ttgagttagg tgaaaaaatt gactttttaa
    60841 tcaaaattcc taagtatatt cttaatgcta ttgcttttgc atgtcaggaa atagtagatc
    60901 tctcaattta taaaaaaatt ctactccata caatcgactt gtacgaggaa actacagaat
    60961 tgtcagcttt atcagctagt ttaaaaacaa gtgatacagc tgatttgaat atagcaataa
    61021 tttctttatt agagtacttt ggtaaagatg aggatgttgt gtatctaatc aatcagatag
    61081 aaaattacac aaaaatactt tatgctgagg tttcaaaatg acaaatatct tcgaaaaaat
    61141 cgtaaatgat ttaaatttag aacaaaaaga tgttgtggaa agtgaagata acctttatgt
    61201 aaatgcatgt cctgggagtg ggaaaacaag ggtacttaca aggaaaattg cttaccaagc
    61261 aattaaacac gatggatcac taaaaagaat aattgctatc acatacacta atagagctgc
    61321 tgaagaaatt aaggaacgcc taagtttact tagtatagat gatgatatta atatttgggt
    61381 ggggacaata catcagtttt gtcttgaatt tattatttat ccttttaaaa tgaatctctc
    61441 aagagtatca aaaggattta caattattga tgattatact caaagagctt acgtcagcca
    61501 aattaataat atgctgaatt taaatctcaa aacgtatgaa ctgaacaaaa ttgatttgtc
    61561 actttctcat gattttaaaa ttaatgaagt tcagtatact caagtttctg aaatgtatca
    61621 cactatgttg gaaaaaaata aagaaattga ttttgatatg attttactag tagcgtataa
    61681 aattttaact gtaaacagta acgttgcacg taatattgct agtaatataa gggcgattta
    61741 tgtggatgaa tttcaagata ctagagaatt acaatacaat gtaatagcta aattacttca
    61801 aaacaaccct caaattcagt caatgtttgt tggagatatt gaccaagcaa tttatggatc
    61861 attagatggt atagctaaat cagttgaaga actagaaatg ctaactagtc acacttttca
    61921 atcaaagacg ctacatggct gttacaggtc taatcagaga ttagtagact tctactctaa
    61981 ttttcagagt tgtccttacg agattgaaag cagagggaat aataaaaacg accgtggttt
    62041 tataagttat gattgcaaag ttactaagga ggatttaccc aacataataa aaaatataat
    62101 aaaggaaaag attgaaagcg gcattcatga aaaagatatt tgtgtacttg ctcctcaaca
    62161 ctatcctctg ttttcactgg gtgagtattt aaagaaagaa ttaccgtatt gcaattttga
    62221 tgctataaat atatcaccaa ttaaggtaaa taatcatagt ttatttttca agttagcaat
    62281 tttgtacttt actgaatcag gtgaaaaggt tcgaagaaga aagctaattg caaacgatat
    62341 tttaattata ttaaaaaatg aatttggaat agaagttaaa gattatttta ttgacttaga
    62401 tttattacag ctaataaaca gtgtgaaaag aatgtatagt ggagacgaca acggtgttga
    62461 tttatacaaa tttgttacca aacatatatt tgttaatctt aatattgacg agaaaaatta
    62521 cccgtctatt tttaagcact atctattttt tattaacgaa gtagaagatc ggataaaaaa
    62581 taattcatta tctagtagtg tatctagttt taagaagatg tttaaatctc gagatggtat
    62641 cacacttact acagcacata aagttaaagg aaatgagtat gatactgtta tcgctattaa
    62701 tcttctaaac gggaaaattc ctcattggaa tgaaattttt aatgtttctg ataaaggaat
    62761 tagttcagcg agaaaactac tatacgtaat ttgttcaaga gcaaaaaata atttatttct
    62821 tttctcagag gtgggttatt ttacgagtaa aggagacttg ctttatccca ctcaattatt
    62881 agataaaata gaatttgatt ataatattta aaatacctag gtagtcgttg ttttaaatat
    62941 agtaggaatc ggacgctcag tacggagcgt ctattttttt acccaatttt gaaaggaagt
    63001 gaacttatga aaataaaaaa tcaagaatca aaaggtcgct ctcccccctt taaaaccatc
    63061 acacaaataa gattcattca aacataaaaa cagaaaggat aggtaaaaat atggaactta
    63121 aatatgtcat tcccaatatg gaaaaaacat ttggacaatt agaatatgct ggtgaaggga
    63181 acattgaaca acgtcgaata aatggcagac caaccattct ctctcgtagt tacaatttat
    63241 actcaacgat tcaacgagca gatgatattg ttgtcattct tccctccgaa gctggcgaga
    63301 aacattttga atccgacgaa aaagtcaaac tcatcaaccc acatattacc gcagaaggtt
    63361 ataaaattgg caatcgagga tttaccaatt acattatgca cgcagacgat atggtgaaag
    63421 cataagaaag gaaaggtgaa aaaatatgag attagcagaa ggtattgtga ttgaaaaaga
    63481 ccagacattt ggcacattga aattttccgc cttgcgtcgt gaggttcgta tccagaatga
    63541 agatggtacg gtttccgaag aaattaaaga acgtacctat gacttaaaat caaaaggaca
    63601 aggacgcatg atacaagtca gtatccccgc ttctgttcct ttgaaagaat ttgactacaa
    63661 cgcagaagtg gaattaatca atcctgtggc agataccgta gcgacggcta cttttcgagg
    63721 ggcagacgtt gattggtacg tgaaagcaga cgatcttgta ttaaaaggac agacaaaacc
    63781 tcatcagaaa tataaaaaag aagcgtccga aagtgaaaaa taggtgttgc ttatgacaaa
    63841 cacaccattg attttgaaag aaattccgaa ggatgaagcc atttctttta ttcggcaata
    63901 ccattattca aagatactcc ctagattgtg taaatacttt ctagggattt tttcagaaga
    63961 aaaattatta ggcgttgtgg aattaggctg gggtacgcaa cccctacaaa ccatacgcaa
    64021 actctttccc gacagttccc ttcaaaccac agattattta gaaattggaa agatgtgttt
    64081 tcttccagaa atgaatcaaa ccaattattt tggcagtcaa gctctttcag ctctaattaa
    64141 gtggttgaaa gaacatacgg actgtcattt tttatataca ctggcagatg gaattgaggg
    64201 aaaatgtggc tatgtctatc aagcgtccaa cttcttttac tgcgggtatt tcaagacaag
    64261 tgtctatcgt gataagcagt catgggaaaa gatacaccct cgaagtgctc gccttttatt
    64321 agaggaaaat gctcgctttg aacaggtaga gaaaaagcat tggctttccc aggcattttg
    64381 cgaatacaaa gggattgaga aaatcaatgg acgcatgttt cgctatctct atccgttgac
    64441 aaaagaagcg aaaaaactgt taggacacac tctctatcga cgtcattatt atccgaaaga
    64501 aaaaaattta cgctttgaaa agcgaatcgc ttatcagaaa tatgaagcca tttctcaacc
    64561 aacttttgat aaacaggctc gtatctacaa tacacaatta ttttgatagg tggaaaggag
    64621 gatttttatg ccattgcttc atgacagagg agagcgaatc aaagccaacg ataagcactt
    64681 ggtctatcat tttgtactaa tttcattgct ggtagttttt ctagtcgtcc tactcccttt
    64741 tcattggaga gcgttacaat cggtgaactg gcaagcagtt cagttagata catttttcta
    64801 tcaacttcat acgccatact tttggagcag tattctcact gctctttttg tatgcggact
    64861 tatcagctgg ctttattatc actatcgtat agattctata aaacagttag agcaccgtca
    64921 aaagttagct cgtatgattt tagaaaatca ttggtatgaa gccgaagaaa ctcaatcaga
    64981 gggattcttt aaagatttac ccagcaagaa aaccaaacaa cgaatccgcc attttcctaa
    65041 aatatattat cgaatgaaag atggactaat ccatattcat gtagaaatca ccttagggaa
    65101 atatcaagat cagcttttgc acctagaaaa caaactagaa acaggattgt attgtgaatt
    65161 agtggaaaaa acgttgaaag attcttatgt agagtatgtc ctactttatg atactattgg
    65221 caatcgaatt ggcattgaag acgtggtagc tcaagatgga cgtgtcaaat tgatggaatc
    65281 ggtctattgg gagttcgatt ctctccctca catgttaatt gctgggggca ctggtagtgg
    65341 aaaatcctat tttattctca cattgattga atctctcctg catacaaatg caaagcttta
    65401 tattcttgac cctaaaaatg ctgatttggc agacttaggg gcggtcatga ataatgtcta
    65461 ttaccgtaaa gaagatatgt tggcatgtat caatcaattt tacgaagata tgattgatcg
    65521 cagtgaaacc atgaaacaac accctaacta taaaacagga gaaaattatg cttatcttgg
    65581 tttgtctgcc aattttctta tttttgatga atatgtggca atgatggata tgctaggtcg
    65641 tgaaagtacc accgttattc ataaactcaa acaaattgta atgttaggac gacaagcagg
    65701 cttcttttta attcttgcct gtcaacgtcc agacgcaaaa tattttagtg atgggattcg
    65761 ggacaacttt aacttccgtg tggctttggg tcgtatgtct gaaatgggct ttggtatgat
    65821 gttcggaagc gatacacaaa aacaattttt cttaaaaccc atcaagggaa gaggttacgt
    65881 ggatacagga aaaagtgtga ttagtgagtt ttatacaccc cttgtaccaa aaaggtacga
    65941 tttcttagga gaaataggaa aagtcattca aaaaaagcaa tctgagcctg taccgcacga
    66001 agtgaaaggt acaggttcag acttgctttg attggtgtgg cgttagccac gccaatcctt
    66061 tagccccctc tatctaacag gggggcacaa atacaactga aaacaggcaa ttctcatcaa
    66121 ccaatgttga tggtacaaag gattgcggaa aatatgaaag gtgtaaactc aagggtcata
    66181 gtttacatct tttttagatt ggaggtttgc gaatggaaaa cgaaaaaatt tggattaagg
    66241 aattgaaaga aaagcgactg gcttatggcg tttctcaaaa taaactggcg gttgcttctc
    66301 atattaccag accttaccta tcggatattg aaacaggcaa ggcagtccct actcaacagg
    66361 tgaaagaaga tttactgaac gctttggaac gcttcaatcc cgataaccca ttggagatgt
    66421 tattcgacta tgtacggatt cgattcccta ccaatgatgt ggctcaaatt atcggtgagg
    66481 ttttacgttt gaatatggat tatatgctac acgaagactt tggctattat tcttatcccg
    66541 aacactatcg tttcggtgat attgttgtcc tagtctctca tgatgtaagt aaaggtgttt
    66601 tattagaact gaaaggaaaa ggctgtcggc aatttgaaaa ctttctattg gctcaacatc
    66661 ggagctggta tgatttcttt caagattgca tggaacataa aggtattttc aaacgcttgg
    66721 atttagctat caacgataaa acagggattt tgaatattcc agatttggca aagaaatgta
    66781 aacaggaaga atgcatttcc gtctttcgaa gctttaaaaa ttatcgcagt ggtgaattgg
    66841 ttcaccgtga tgaaaaacca tacatgggaa acacacttta tattggctca ttaaaaagtg
    66901 aagtctattt ctgtatatat gagaaagatt atgagcaata cgtgaaaaat gatgttccct
    66961 tagaagacgc agaagtaaag aatcggtttg aaattcggtt aaaaaatgac cgagccaccc
    67021 aagccatgaa agatttattg gcacatcaac aggcggaaaa aacagccttt gaaattatca
    67081 atcgctatat ccgctttgca gataaagacg acactaaacg tcggagtgat tggaaaacta
    67141 atgaacgttg ggaatggttt atcggtaaaa atcgtggagc attacgccta accacacagc
    67201 cagagcctta ttcttttgaa cgaacattga actggttaca tcatcaagtc gcccctacat
    67261 taaaaatcgc aagcatttta gatgttctca acggtacaac cattatctcc accatgattc
    67321 aggaagccaa actgacagaa aaacatgaga aattaattga acaacaacat ctagccatgg
    67381 aggatttgat tacatgagcc ttttaacaaa agaattaaag aagttagggt ttcagtgtgg
    67441 cattgagttt caagcgtata tacaaaatac agggaaatat acgtctctca ttattgaggg
    67501 aaaacggcaa gctggtgata ccatctatac ctatgatttt tacaaggtga gattttataa
    67561 taattatacc aatcgagtaa ccgtctatgg agagcattta accccttttc aattattaag
    67621 gcgtgtaaaa agctatatct attatcgaga aaaatatctt aaggaaagga ggacaatcac
    67681 atgaattttg ggcagaattt gtacaactgg ttcttggata atgcacagtc attggtattg
    67741 ttagcgattg ttgtcattgg actgttttta ggttttaaac gagaattttc aaaactcatt
    67801 ggcttcttga ttattgctct aatcgccgtc ggacttgtgt tcaatgcagc tggcgtgaaa
    67861 gatgtgttat taaacttatt taaccgaatc attggtgctt aacagatatt tttcatgata
    67921 aaataggaag tatatatttt gttatgaaag gatttatgaa tatgtttaca aatgatcaat
    67981 ttaaatctct tttaattaaa acattagaaa gaaagagctc ttcaaattat tatgaaggag
    68041 gtaacgagat tgtttctaaa atgaaaatat cagaggtaac tttagatgag actgacgatt
    68101 ttacttatta taaaggatat aaaaagggct ggaatacgct ttgcacatat cttaaaataa
    68161 gagttccttt tgatgattta gacttttttg aaagtcataa agatttgatt acccagacag
    68221 caagctccat atatgataaa caaggtgata atgtattagt ggatactatt ttagtaccac
    68281 ttccagagaa ttacgaagta attaacttta gtcagttgaa aattagtgat gtggtttcac
    68341 aagctattga agacgctgag tcttttatga gtaatggtga atatcaacgt gcctttgaca
    68401 gagttcacac tgcttttcat ggatatttaa ttgaaatact aaaaaaatat gaaattacag
    68461 ttcctagaga cgaaaatcta tctaaattat atagtaggat acaacaatta attgaaaaag
    68521 aaattcaacc tactgaactt gctgatatag tgaagacaac gataaggtca tcaaatggaa
    68581 tgattagctc tcttaatgaa gcaagaaata ggcattcact tgcacaccct aatacaaata
    68641 ttattggaaa gagagaagca aaactaataa taggtatttc aagtacagtt acagattata
    68701 ttagcggata ccttgataag tagcgtcatt aactgattgc tacttttttt atgactattt
    68761 ttataaaaag gatgtgataa gaattggaaa tgaaagtcta tgtggcaaat ttaggacggt
    68821 ataatgaagg tgaattagtc ggagcatggt ttactccacc aattgatgag gaagaaatgg
    68881 cagaaagaat cggtttaaat gaggactacg aagaatatgc aatacatgat tttgagcttc
    68941 cttttgatgt ggacgaatac acgccgatta gtgaaatcaa ccgtctatgt gaagccattc
    69001 aagaaatcga aggtacacct atttataatg aactcaaaga aattcaaggc atgtggttta
    69061 gtagcttgga agaattactg gaaaacaaag aggatattca ttgttatagt gattgtgatt
    69121 cgatggaaga tgtcgcccgt tattacgtgg aagaaacagg acagcttggt gaagtccctt
    69181 ccaatttaca aaattatatt gactaccaat ctttgggacg tgatatggaa atagagggta
    69241 attacctagt tacctctcat ggggtatttg aatattgtca gtaagtttaa caatccgtgt
    69301 tataattaaa ttaataaata gcacggagag gtataaatta tggtaaatgt atttgaaaat
    69361 cttaaactat taaaactaga catgaaagat aaaggctggg tgatagattc cttttacttt
    69421 cgttacaaac agcaaaatta tattgtactt gttaagctat ttgaaaaaga ggaaaaagtt
    69481 ccagaatatg ctctgttaaa actagaattt ttaaaggaaa acgatttttc agatatgcta
    69541 gctgtctatg ctaattcggt aaaattatat acagacacga aaacaataag agaatatttt
    69601 ggtatcgaat acagtagtaa cttgggagat gttttatttc aatttagcca aactcttgct
    69661 cgatttattc cgacagaagt tagtgagaag aaaaatgaag accaaaaaga agccatgtgt
    69721 ttctcattaa gtcaaagtga ttcagaagat cccagaaaaa aatattgttt ttcagttaga
    69781 agaaatcctt taaagggaaa tggtgagctg ggaaaacgaa gtccttttaa tgacaataaa
    69841 acgagattgt atagacccag cttatatgaa cgattagggt cagataccaa tttaagtttc
    69901 agatattcaa tgaatccaga tgatgaagaa actgatgaag gtattattgc aaaatggaca
    69961 aaaaataaaa ttgaatagtt aaagcattga aagagcaatc acctattttg attgttcttt
    70021 ttctattttt acggaaagga cgtgaagaca tgaaaaaaat aagaagttac accagtattt
    70081 ggtcagtaga aaaagtgatt tatgcgatta atgatttaca actccctttc ccaattacct
    70141 ttacgcaaat gacatggttt atcgtttctt tgtttgtcgt catactcttt ggcagtttac
    70201 caccactttc tctgattgac ggagcactac tcaaatactt agggattccc attgttctca
    70261 ctgggttcat gtgccaaaag acctttgacg gaaagaaacc ctatggattt ctaaagtcta
    70321 tcattaccta tgctctacgc cctaaagtaa cctacgctgg caaacaaata cgattaaaaa
    70381 aagaaacaat gaatgaatcg attacgattg taaggagtga acaactagat ggcatatccg
    70441 attaaatata tggaagataa tctcgtattt aatcatgatg gcgaagtatt cgcttattat
    70501 gaattaattc cctataatta cagtttttta agttccgatg aaaaaattca agttcatgat
    70561 aatttctgtc aattgattgc ccaaaatcgt gatggcaaga ttcatgctct gcaactagca
    70621 accgaatcaa gtattcgagc cacacaggaa caatcgaaaa aagaaatcac tggacgatta
    70681 aaagagatag cttacgaaaa aatagatgaa cagaccgaag cgttaatttc tatgattggt
    70741 gacaatcaag tagactatcg cttttttatt ggttttaaac tctacctcaa tgaacaggaa
    70801 gtatccgtaa aaaatgttgg gaaagaaatt caaaaagcat ttgcggaatt ctttcatggt
    70861 gtgaatcaca aattaatggg cgattttgtt tctatgccta tggcggaaat cgaacgcttt
    70921 tctaagatgg aacagttgtt agaaagtaaa ttatccagac gctttcagat tcgtaaattg
    70981 gagaaagatg attttggtta tattattgaa catctttacg ggcaaacagg tgtccctttt
    71041 gatgactacg actaccattt accgaaacga tacgaagata aaaaagtgtt ggtaaagaaa
    71101 tacgatattc tcaaacccac tcgctgttta atcgaagaaa atcaacgcta tttacggatt
    71161 gaacaggaag ataccactac ttatgtggcg tattttacaa ttaatagtat tgttggtgaa
    71221 ttggatttcc ctaatagtga aattttttat taccagcaac agcagtttac tttccccgtt
    71281 gataccagta tgaatgttga aattgtcgcc aataaaaaag ccttatctac cgttcgcaat
    71341 aaaaagaaag aactgaaaga tttagatagc cacgcatggg aaagcgacaa cgaaaccagt
    71401 actaatgtgg tggacgcttt agaatctgtc gatgaattag aaagtaattt agaccaaacc
    71461 aaagaatcta tgtacaaact aagctatgtg gtacgggtat cagcaaagaa tttggacgag
    71521 ctgaaacaac gttgtgatga agtaaaagat ttttatgatg atctgtctat caaattagta
    71581 cgaccttttg gcgatatgct aggcttgcat aatgaattta ttccctcaag caagcgatat
    71641 atcaatgact atattcaata tgtcacgtcg gattttttgg ctggtcttgg tttcggtgct
    71701 acacaaatga ttggtgaaaa ttctggtatt tacgtcggtt acaatctcga tacaggcaga
    71761 aatatttatc tccaacctag ccttgcaagt caaggaatta aaggctctgt aacaaatgca
    71821 ttagcgtccg cttttattgg ttcattaggt ggcggaaaat cattctctaa caatatgctg
    71881 gtctattatt cagtactctt tggcggacag gcaaccattg ttgacccaaa agctgaacgt
    71941 ggtgaatgga aagaaacctt acctgatatt gcccatgaaa tcaatattgt taatctcacg
    72001 agtgagaacg acaataaagg gttacttgac ccttatgtga ttttaaaact cccgaaagat
    72061 tcagaaagcc ttgccattga tattctcacg ttcttaacag gtatttccag ccgagatagc
    72121 gagaagtttc ctgtcctgcg taaagctatt cggagtgtaa ctcaaagcaa acaacgaggg
    72181 ttgttattgg tgattgatga attgcgaaaa gaagatacgc ccatcagcaa tagtattgct
    72241 gaccatatcg aaagctttgt cgattatgat tttgcccatc tgttattcag tgatggcagt
    72301 gtcacccaat ccattagctt ggaaaaacaa ctcaatatta ttcaagtggc agatttggtc
    72361 ttacccgatt ccaatagctc ttttgaagaa tacactacca tggaattatt aagtgtggca
    72421 atgctgattg tcattagtac ctttgcttta gactttatcc actctgaccg ttccattttt
    72481 aaaattgttg accttgatga ggcttggagt tttttacaag tggcacaagg aaaagctcta
    72541 tctatgcgat tggttcgagc aggacgtgcc atgaatgcag gggtctattt cgttactcaa
    72601 aacgcggacg atttactaga tgaaaagatg aagaataata ttggcttgaa atttgccttt
    72661 cgttccactg acctagtgga aatcaaaaag accttagaat tttttggtgt ggacaaggaa
    72721 gatgaaaaca atcagaaacg cttacgtgaa ttagaaaatg gacaatgttt agtttcagac
    72781 atctatggtc gtgtaggggt tatgcagttt cacccgattt ttgaagagtt gcttcatgcc
    72841 tttgatacca gaccgcctgt gcgaaatgag gtggaagaat gacacaaaaa caaaagaaat
    72901 ttcttcacta tagttggata acgctccttt gtgtgggcgt tattttactt ttattaggca
    72961 cgctgggcaa tgcagtacaa gcgacaggct tagttgatga aaccattgat acaagcaatg
    73021 aatactccaa gtatggtttg aatcaatatc agcttgatta ttatgtggac aatagctggg
    73081 gctggcttcc atggaattgg agtgatggca taggacaatc ggtgatgtat ggattgtatg
    73141 ccattactaa ttttatttgg acaatttctc tttatctatc gaacgccaca ggttatttgg
    73201 tgaaagaagc ctatgcctta gatttcatta gtcaaacatc ccaagcaatt ggcgaaaaca
    73261 tgcagacgat tgcaggcatt acaccgaatg gcttttccag ttcagggttt tatgtcggtt
    73321 tcctccttct ttttattctc attgttggaa tctatgttgc ctatacagga ttggttaagc
    73381 gagaaacgac gaaagtgata cgagctgttt taaactttgt cgtggtgttt attctatcgg
    73441 cttcctttat tgcgtatgca cccgattata ttgcgaaaat caatgatttt tccaaagatg
    73501 tcagtaccgc cagtctgaat attgggacaa aaattgttct tcctaacacg gatagtcaag
    73561 ggaaagacag tgtggacatg atacgtgaca gcttattctc tgttcaagta aagcaaccat
    73621 ggctattgct tcaatatggc tccactgatg tagaagcgtt aggggaagaa cgtgtggaaa
    73681 gtttattgtc taccagtcca gatacaaaca atggtgaaga tagagaaaat gtagtgattg
    73741 aagaaattga agatcatgac aatacctatt taaccctacc gaagacgatt tccagattag
    73801 gaacagtctt ctttttgttt gtattcaata ttggtatctc gatttttgtt ttccttctaa
    73861 caggaatcat gattttttcg caagtgctat ttattatttt cgctatgttt ttgccaatca
    73921 gtttcctatt aagtatgttg ccgagttttg atggcatggg caggcatgcc attaccaagt
    73981 tatttaatgt gattatgaca agggctggta ttaccttgat tattaccgtt gcctttagta
    74041 tttccactat gctttattcg ctgtcagcaa gttctccctt tttcatgatt atgtttttac
    74101 aaattgtgac ctttgcaggg atttatttta aactgggcga tttaatgagc ctattcactt
    74161 tacaaagcaa cgactctcaa aacatgggca gacaagtgtt tcgcagacct cgtcaaatga
    74221 tgaatcgaca aaccagaaga tttcaacgca gtatgagtaa gatttttcgt ggaaaagcag
    74281 ggtcaacgaa gcaaaagaca atgacaacaa agcagaatca aaccaataaa gctaaccata
    74341 ctcgtcaaaa tgaacggact acaccaaaga aagaaacagc actttccaat gtgaaaaagc
    74401 aacaaggcgg tatcgggcaa cgattaggtg aaaagacagc ccatgtattg gacacgaaaa
    74461 atcgtctagt caataaaaga aagcaggcaa aacaacagat acaggcgaca ccaacccatg
    74521 tcaaatatgc ccttcatcaa ggaaaagaga atgtcactca taatgtaaca gactttaaac
    74581 aatctatggc agataccaaa gctcaacgca aacaacagcg tatgaaccag caggagcaaa
    74641 aacgaaagaa cattgctcaa aagcgtttgg agctggataa agcaaaagaa aaaagacgaa
    74701 aagaaaaccc atcatctcct gttcagaata accagcagca tgttcgcaag cgtcagcaaa
    74761 ccgtcacgcc tgttttgtca caaaacacta aacgtgaaaa tcatcagcga ccattgaaaa
    74821 aagagcaaaa acaaaagaca ccaccgaagc aattcaatca gaggaagcta aataaaagaa
    74881 cggataagcg aggacaacaa acatgaagct aaaaataaca gtgatttgta gtgtggtctt
    74941 ctctctcttc ttttttctct tattattcct agtcattttc tttgcagatg atacggacag
    75001 tggcgaaaac aacaaggatt cttctattcc acaaggcggt gtgaccgttt caccagaagt
    75061 gttggcacac cgtccgttga ttgaaaaata tggtaaggaa tatgggattg aagactatgt
    75121 ttcttatatc ttagccatta tgcaagtgga atcgggcggt acagcagaag atgttatgca
    75181 aagttccgaa tctttgggtt taccgcccaa cagtttgagt accgaagagt ccatcaaaca
    75241 aggggttaaa tatttcagtg aattattaac cagtgcagaa caacaaggag tggatataga
    75301 ttctgttatc caatcttata attatggcgg tggcttttta aattatgtga ggagtcatgg
    75361 gaaaaaatat acctatgaat tagccgaaca gttttctaaa gagaagtcgg gtggtcaaaa
    75421 agcagactat cccaatccta tagccatacc tgtgaatggt ggttggcgat ataactatgg
    75481 aaatcagttt tatgttcagt tggtttcaca atacctaacc gacacttccc caacagaatt
    75541 tgatgatgaa accgtgcaag tcattatgga cgaagccttg aaatacgaag ggtttcccta
    75601 tgtctttgga ggggcgtcgc ctaccacctc ttttgattgt agtggcttaa tacaatgggt
    75661 gtatgacaaa gctggcattt ctctccctcg tgtcgcccaa gatcagtatg acgctacgca
    75721 agaaatctct atggaagaag cccaagcagg cgaccttatc ttctttcatt caacctataa
    75781 tgcaggcaca tatgtgactc atgtggcgat atatttagag ggaaatcgct tttatcatgc
    75841 aggcgaccca atcggttatg gcgacttaag cagtcgttat tggcaagacc atctgattgg
    75901 ggctagacgt gttattcata actaagaaag gaatgaatca aatgattata aaaatcgagc
    75961 gaaaagaaaa gaaggagaaa ccaaagaaat ctaaaaaacc gagcaagcaa agaaaagttc
    76021 cgatgattaa agttggcacg cataagaaat taacctttgt tttatgggtt ttattgattg
    76081 gtagtgtcgg atttggaatc tataaaaatt ttactgccat tgacactcat actgtccgtg
    76141 aaacagaaat cattaaacag cagattgtcg ataccaacca agtagaaagt tttgtgaaat
    76201 cctttgcgaa agactacttt tcgtggcaac aatcccaaga agccattgat aaacgaaatg
    76261 aaaaattgac ccattatttg acggaagaat tgcaggtatt aaatgaagaa atgattcgta
    76321 aggatattcc tactagttct agtgtgaacg atatacaggt gtggcaggtt tctcaagtga
    76381 atgagaacac ctttgaggta ctgttttctg ttgaacaagt tattaccgaa gacaaagaca
    76441 aggaaactat atcgtctagc tttcatgtgg ttgtccatat agatgaatca gataatatgg
    76501 ttattatcaa aaatccgaca atgagtaaga aacctcaaaa atcggactac caacccaaac
    76561 agctagaaag tgaccataca gtagatacag aaacgatgga cgaaatcact agctttttag
    76621 aaacgttctt ccagctctat cctaccgcca cagaaaaaga attgacttac tatgtaagta
    76681 atcatgtgtt acctatgatt aacaaggaat atgttttcga ggaattggtg aatcctatct
    76741 ttaccagaaa agataaccaa gtaatcgtga atgtcgctgt gaaatattta gatcaagaaa
    76801 caaaggcaac ccaaatctcg caatttgagt tgatattaga aaaacaagat aattggaaga
    76861 ttgtaaaata acaaatattg gtacatgatt acagatactt tgtaatcatg tactcttttt
    76921 gataaaaaat tggagattcc tttacaaata tgctcttacg tgctattatt taagtgacta
    76981 tttaaaagga gttaataaat atgcggcaag gtattcttaa ataaactgtc aatttgatag
    77041 cgggaacaaa taattagatg tcctttttta ggagggctta gttttttgta cccagtttaa
    77101 gaataccttt atcatgtgat tctaaagtat ccagagaata tctgtatgct ttgtatacct
    77161 atggttatgc ataaaaatcc cagtgataaa agtatttatc actgggattt ttatgccctt
    77221 ttgggttttt gaatggagga aaatcacatg aaaattatta atattggagt tttagctcat
    77281 gttgatgcag gaaaaactac cttaacagaa agcttattat ataacagtgg agcgattaca
    77341 gaattaggaa gcgtggacaa aggtacaacg aggacggata atacgctttt agaacgtcag
    77401 agaggaatta caattcagac aggaataacc tcttttcagt gggaaaatac gaaggtgaac
    77461 atcatagaca cgccaggaca tatggatttc ttagcagaag tatatcgttc attatcagtt
    77521 ttagatgggg caattctact gatttctgca aaagatggcg tacaagcaca aactcgtata
    77581 ttatttcatg cacttaggaa aatggggatt cccacaatct tttttatcaa taagattgac
    77641 caaaatggaa ttgatttatc aacggtttat caggatatta aagagaaact ttctgccgaa
    77701 attgtaatca aacagaaggt agaactgtat cctaatatgt gtgtgacgaa ctttaccgaa
    77761 tctgaacaat gggatacggt aatagaggga aacgatgacc ttttagagaa atatatgtcc
    77821 ggtaaatcat tagaagcatt ggaactcgaa caagagga
//
LOCUS       DAXQKX010000004        72432 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.004, whole genome shotgun sequence.
ACCESSION   DAXQKX010000004 DAXQKX010000000
VERSION     DAXQKX010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 72432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72432
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.004"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(160..444)
                     /locus_tag="ACF3MF_000291"
     CDS             complement(160..444)
                     /locus_tag="ACF3MF_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926323.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(462..1352)
                     /locus_tag="ACF3MF_000292"
     CDS             complement(462..1352)
                     /locus_tag="ACF3MF_000292"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YicC/YloC family endoribonuclease"
                     /protein_id="HFE3926324.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(1372..1590)
                     /locus_tag="ACF3MF_000293"
     CDS             complement(1372..1590)
                     /locus_tag="ACF3MF_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HFE3926325.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(1560..3260)
                     /locus_tag="ACF3MF_000294"
     CDS             complement(1560..3260)
                     /locus_tag="ACF3MF_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HFE3926326.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            3527..4300
                     /locus_tag="ACF3MF_000295"
     CDS             3527..4300
                     /locus_tag="ACF3MF_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926327.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(4381..4950)
                     /gene="thiT"
                     /locus_tag="ACF3MF_000296"
     CDS             complement(4381..4950)
                     /gene="thiT"
                     /locus_tag="ACF3MF_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015234 - thiamine transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015888 - thiamine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HFE3926328.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(5016..5118)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(5124..6095)
                     /locus_tag="ACF3MF_000297"
     CDS             complement(5124..6095)
                     /locus_tag="ACF3MF_000297"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFE3926329.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(6189..7562)
                     /gene="glmU"
                     /locus_tag="ACF3MF_000298"
     CDS             complement(6189..7562)
                     /gene="glmU"
                     /locus_tag="ACF3MF_000298"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HFE3926330.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(8065..8883)
                     /gene="purR"
                     /locus_tag="ACF3MF_000299"
     CDS             complement(8065..8883)
                     /gene="purR"
                     /locus_tag="ACF3MF_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HFE3926331.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(9050..9874)
                     /locus_tag="ACF3MF_000300"
     CDS             complement(9050..9874)
                     /locus_tag="ACF3MF_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HFE3926332.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(9847..10527)
                     /locus_tag="ACF3MF_000301"
     CDS             complement(9847..10527)
                     /locus_tag="ACF3MF_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFE3926333.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(10550..11488)
                     /locus_tag="ACF3MF_000302"
     CDS             complement(10550..11488)
                     /locus_tag="ACF3MF_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HFE3926334.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(11733..12584)
                     /gene="ispE"
                     /locus_tag="ACF3MF_000303"
     CDS             complement(11733..12584)
                     /gene="ispE"
                     /locus_tag="ACF3MF_000303"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050515 - 4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HFE3926335.1"
                     /translation="MELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADHLFFE
                     EITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAGLGGG
                     STDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQVLPS
                     MPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMGNSLE
                     DITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCEEV
                     YLVRTLQ"
     gene            complement(12738..15311)
                     /gene="mprF"
                     /locus_tag="ACF3MF_000304"
     CDS             complement(12738..15311)
                     /gene="mprF"
                     /locus_tag="ACF3MF_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HFE3926336.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLP
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            15452..16258
                     /gene="proC"
                     /locus_tag="ACF3MF_000305"
     CDS             15452..16258
                     /gene="proC"
                     /locus_tag="ACF3MF_000305"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HFE3926337.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(16337..17893)
                     /gene="rny"
                     /locus_tag="ACF3MF_000306"
     CDS             complement(16337..17893)
                     /gene="rny"
                     /locus_tag="ACF3MF_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HFE3926338.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(18304..19353)
                     /gene="recA"
                     /locus_tag="ACF3MF_000307"
     CDS             complement(18304..19353)
                     /gene="recA"
                     /locus_tag="ACF3MF_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HFE3926339.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(19462..20703)
                     /locus_tag="ACF3MF_000308"
     CDS             complement(19462..20703)
                     /locus_tag="ACF3MF_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HFE3926340.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(20943..21521)
                     /gene="pgsA"
                     /locus_tag="ACF3MF_000309"
     CDS             complement(20943..21521)
                     /gene="pgsA"
                     /locus_tag="ACF3MF_000309"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HFE3926341.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(21730..22653)
                     /locus_tag="ACF3MF_000310"
     CDS             complement(21730..22653)
                     /locus_tag="ACF3MF_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RodZ domain-containing protein"
                     /protein_id="HFE3926342.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(23392..24678)
                     /locus_tag="ACF3MF_000311"
     CDS             complement(23392..24678)
                     /locus_tag="ACF3MF_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFE3926343.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(24671..25939)
                     /locus_tag="ACF3MF_000312"
     CDS             complement(24671..25939)
                     /locus_tag="ACF3MF_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFE3926344.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            26191..26652
                     /gene="mscL"
                     /locus_tag="ACF3MF_000313"
     CDS             26191..26652
                     /gene="mscL"
                     /locus_tag="ACF3MF_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HFE3926345.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(26711..27157)
                     /locus_tag="ACF3MF_000314"
     CDS             complement(26711..27157)
                     /locus_tag="ACF3MF_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFE3926346.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(27250..27495)
                     /locus_tag="ACF3MF_000315"
     CDS             complement(27250..27495)
                     /locus_tag="ACF3MF_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HFE3926347.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(27609..28187)
                     /locus_tag="ACF3MF_000316"
     CDS             complement(27609..28187)
                     /locus_tag="ACF3MF_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFE3926348.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(28264..28794)
                     /locus_tag="ACF3MF_000317"
     CDS             complement(28264..28794)
                     /locus_tag="ACF3MF_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HFE3926349.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(28798..29658)
                     /gene="rlmB"
                     /locus_tag="ACF3MF_000318"
     CDS             complement(28798..29658)
                     /gene="rlmB"
                     /locus_tag="ACF3MF_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HFE3926350.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(29651..30046)
                     /locus_tag="ACF3MF_000319"
     CDS             complement(29651..30046)
                     /locus_tag="ACF3MF_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HFE3926351.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(30043..31455)
                     /gene="cysS"
                     /locus_tag="ACF3MF_000320"
     CDS             complement(30043..31455)
                     /gene="cysS"
                     /locus_tag="ACF3MF_000320"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HFE3926352.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(31452..31988)
                     /gene="epsC"
                     /locus_tag="ACF3MF_000321"
     CDS             complement(31452..31988)
                     /gene="epsC"
                     /locus_tag="ACF3MF_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase EpsC"
                     /protein_id="HFE3926353.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLFANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(32074..32313)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(32310..33770)
                     /gene="gltX"
                     /locus_tag="ACF3MF_000322"
     CDS             complement(32310..33770)
                     /gene="gltX"
                     /locus_tag="ACF3MF_000322"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HFE3926354.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(33940..35097)
                     /locus_tag="ACF3MF_000323"
     CDS             complement(33940..35097)
                     /locus_tag="ACF3MF_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HFE3926355.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(35131..36501)
                     /gene="radA"
                     /locus_tag="ACF3MF_000324"
     CDS             complement(35131..36501)
                     /gene="radA"
                     /locus_tag="ACF3MF_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HFE3926356.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(36564..37091)
                     /locus_tag="ACF3MF_000325"
     CDS             complement(36564..37091)
                     /locus_tag="ACF3MF_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HFE3926357.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            37321..38127
                     /gene="proB"
                     /locus_tag="ACF3MF_000326"
     CDS             37321..38127
                     /gene="proB"
                     /locus_tag="ACF3MF_000326"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HFE3926358.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            38124..39371
                     /locus_tag="ACF3MF_000327"
     CDS             38124..39371
                     /locus_tag="ACF3MF_000327"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HFE3926359.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            39447..39791
                     /locus_tag="ACF3MF_000328"
     CDS             39447..39791
                     /locus_tag="ACF3MF_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926360.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(39908..40234)
                     /locus_tag="ACF3MF_000329"
     CDS             complement(39908..40234)
                     /locus_tag="ACF3MF_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926361.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(40607..41808)
                     /locus_tag="ACF3MF_000330"
                     /pseudo
     CDS             complement(40607..41808)
                     /locus_tag="ACF3MF_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            41925..42440
                     /locus_tag="ACF3MF_000331"
     CDS             41925..42440
                     /locus_tag="ACF3MF_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFE3926362.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(42639..43085)
                     /locus_tag="ACF3MF_000332"
     CDS             complement(42639..43085)
                     /locus_tag="ACF3MF_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HFE3926363.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(43132..44610)
                     /gene="msr(C)"
                     /locus_tag="ACF3MF_000333"
     CDS             complement(43132..44610)
                     /gene="msr(C)"
                     /locus_tag="ACF3MF_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HFE3926364.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(44964..45593)
                     /locus_tag="ACF3MF_000334"
     CDS             complement(44964..45593)
                     /locus_tag="ACF3MF_000334"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFE3926365.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(45577..46041)
                     /locus_tag="ACF3MF_000335"
     CDS             complement(45577..46041)
                     /locus_tag="ACF3MF_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFE3926366.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(46528..47796)
                     /locus_tag="ACF3MF_000336"
     CDS             complement(46528..47796)
                     /locus_tag="ACF3MF_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFE3926367.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(48027..48764)
                     /locus_tag="ACF3MF_000337"
     CDS             complement(48027..48764)
                     /locus_tag="ACF3MF_000337"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFE3926368.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(48831..49400)
                     /locus_tag="ACF3MF_000338"
     CDS             complement(48831..49400)
                     /locus_tag="ACF3MF_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DapH/DapD/GlmU-related protein"
                     /protein_id="HFE3926369.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            49528..50400
                     /locus_tag="ACF3MF_000339"
     CDS             49528..50400
                     /locus_tag="ACF3MF_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFE3926370.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            50742..51614
                     /locus_tag="ACF3MF_000340"
     CDS             50742..51614
                     /locus_tag="ACF3MF_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFE3926371.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            51611..53569
                     /gene="nagE"
                     /locus_tag="ACF3MF_000341"
     CDS             51611..53569
                     /gene="nagE"
                     /locus_tag="ACF3MF_000341"
                     /EC_number="2.7.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015572 - N-acetylglucosamine
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-specific PTS transporter
                     subunit IIBC"
                     /protein_id="HFE3926372.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(53820..54671)
                     /locus_tag="ACF3MF_000342"
     CDS             complement(53820..54671)
                     /locus_tag="ACF3MF_000342"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFE3926373.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            54794..55261
                     /locus_tag="ACF3MF_000343"
     CDS             54794..55261
                     /locus_tag="ACF3MF_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HFE3926374.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(55524..56006)
                     /locus_tag="ACF3MF_000344"
     CDS             complement(55524..56006)
                     /locus_tag="ACF3MF_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFE3926375.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(56106..56969)
                     /locus_tag="ACF3MF_000345"
     CDS             complement(56106..56969)
                     /locus_tag="ACF3MF_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFE3926376.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            57567..58415
                     /locus_tag="ACF3MF_000346"
     CDS             57567..58415
                     /locus_tag="ACF3MF_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SWIM zinc finger family protein"
                     /protein_id="HFE3926377.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
     gene            complement(58586..58927)
                     /locus_tag="ACF3MF_000347"
     CDS             complement(58586..58927)
                     /locus_tag="ACF3MF_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HFE3926378.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SMEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAAEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            59013..59720
                     /locus_tag="ACF3MF_000348"
     CDS             59013..59720
                     /locus_tag="ACF3MF_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HFE3926379.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            59707..60030
                     /locus_tag="ACF3MF_000349"
     CDS             59707..60030
                     /locus_tag="ACF3MF_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HFE3926380.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(60119..61156)
                     /locus_tag="ACF3MF_000350"
     CDS             complement(60119..61156)
                     /locus_tag="ACF3MF_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HFE3926381.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(61603..62586)
                     /locus_tag="ACF3MF_000351"
     CDS             complement(61603..62586)
                     /locus_tag="ACF3MF_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase"
                     /protein_id="HFE3926382.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ"
     gene            complement(63002..63772)
                     /locus_tag="ACF3MF_000352"
     CDS             complement(63002..63772)
                     /locus_tag="ACF3MF_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFE3926383.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(63765..64700)
                     /locus_tag="ACF3MF_000353"
     CDS             complement(63765..64700)
                     /locus_tag="ACF3MF_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3926384.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(65294..66943)
                     /locus_tag="ACF3MF_000354"
     CDS             complement(65294..66943)
                     /locus_tag="ACF3MF_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFE3926385.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            complement(67138..68034)
                     /locus_tag="ACF3MF_000355"
     CDS             complement(67138..68034)
                     /locus_tag="ACF3MF_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFE3926386.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWVDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDSFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(68027..68707)
                     /locus_tag="ACF3MF_000356"
     CDS             complement(68027..68707)
                     /locus_tag="ACF3MF_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFE3926387.1"
                     /translation="MFLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(68708..69490)
                     /locus_tag="ACF3MF_000357"
     CDS             complement(68708..69490)
                     /locus_tag="ACF3MF_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFE3926388.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(69483..70400)
                     /locus_tag="ACF3MF_000358"
     CDS             complement(69483..70400)
                     /locus_tag="ACF3MF_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFE3926389.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(70403..70687)
                     /locus_tag="ACF3MF_000359"
     CDS             complement(70403..70687)
                     /locus_tag="ACF3MF_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926390.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWQTTQPRLRDSLIFLEIQLENLHFLYTFLAAFFIPVNYTSLINKKEG"
     gene            complement(71388..72008)
                     /locus_tag="ACF3MF_000360"
     CDS             complement(71388..72008)
                     /locus_tag="ACF3MF_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926391.1"
                     /translation="MNINRVIKLIGAKNINKVRSEFIFPEDFFNWFFYQFSECKRLLG
                     ENYYLKGIGGFMGNVADEQNIIKGISEQTSELTVTKAFISNGESLKNVTARIRKENEV
                     DIVFGIDHECNSVIYVTQSANLILFENGCKDDFMVVYLYDILIPKLRSLYMSSESIFV
                     SEQKGSFSKKIGIEVIESIMCHNHITLEELEILIGQKNNNTKIQVS"
     gene            complement(72089..>72432)
                     /locus_tag="ACF3MF_000361"
     CDS             complement(72089..>72432)
                     /locus_tag="ACF3MF_000361"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926392.1"
                     /translation="NIKTSTKLICKLFKLDKISNIDDVKSKILTRKVSEPVKLTAQDK
                     KNGIVLYGDDAKYNYNWDTSSEAEVLSIPTTDTSGEKVTFKINFITAISKLEYGKQKK
                     RDNNDQYLPKK"
BASE COUNT        20829 a        15442 c        12750 g        23411 t
ORIGIN      
        1 aataccgaga aaatggtttt tgaacatcac ttattcaaaa taaaaaaaga ttgtgacacg
       61 aattttgtca caacctttaa atgtattcct agagcaaaga agctaagcga agaaatccaa
      121 ttctgattat ttattgtatt tctttgttca gcatccttgc taaaagccca tattggacaa
      181 agtattcact acacccatga tctcatcttt tcgagaacgt gctttttctg tcggatcttc
      241 tacctcttct gtgtcaattc gaacaataaa tttccgattc atcgtcacgt aagcaccgtc
      301 gttgatcaaa ataaacagtt cgttctcatt atagtctgca caggcatctt tccatacgtc
      361 aaagccgttt ttttcagaag ggatatcccg tttaaccaca gtttttccac ttaattcgtg
      421 gaacgttacg tcataatatt tcattatctc tacctctttc gtcattcaat attttgtact
      481 tgttctctga ttttttctaa gatcgtctta gactggacga cttgattttt aatttcgatt
      541 gcatttgatt tggaaccgat cgtgttgatt tcccgattca tttcttggat caggaaatct
      601 aattcccgac ctacaggaca ttgtgcttcg ataagttcat ctagtttttg tacatggatc
      661 gccagacgat ccagttcctc gtgaatatct ccgcgttcca acaagatggc tagctccgtc
      721 aacaaccgtt gctcatcgac tttcgctcca agaaattcct ccagcttttt ttgatacctt
      781 atttgaaatt ccttttcata gatttctaca aaactatcga gtttttttag tacttctttg
      841 aattcttcag tattcttttt caacactaaa gctaaagctt gaccttcttt ttctcgactc
      901 gcctcaatag aatcaagtgc gcttttcaat gtatctagag ctaactgtgc caattcttcc
      961 atgctctctt ccggtttttc ttctaccgtt acgaagtttt cgtccagcgc gaagcgttcc
     1021 gccatccgac taattgacac ttgattttga ctaccgtatc gttgttgaat tccgtctgtc
     1081 aattgagtga taagtgaatc aatcaattcc cagttgatga cgatctgttt ttcgtttttg
     1141 ccaatataag ctagattcac aaatacttcg attcgaccgc ggcttaactg ctgtttaata
     1201 agctgacgaa aatcgttttc aacaaagttc aggattttag gacttcgtat ttgaacatct
     1261 agaaaacgct ggttgacact ttttatttca atatctaact gatacgcttt tgtttcgcgg
     1321 atggctttgc caaaaccagt catacttttc attcgacagg gtccttcctc attacatatt
     1381 ttctattgct ttttgcagtt gttcaaactc ttcgttcgtc aatgtcaggc ctttccccat
     1441 tttttcatgg tctggcgccc aatctcgaag atcgaatttt ggcgggcgac cattccagct
     1501 gactaggttc agttctttac gccacccctt gttgttttct gacaatatag cgatttcttc
     1561 tacgatttca tatgaaaatt cttgtgccat ggttgttcct ccttgagata atataaatat
     1621 aggatcagta atgtgtcaac tggttgctta agcaattcat gctgcaaacg atccttgcgt
     1681 tttccttgta gcagataatc aaaataaaca gttttcgtgc gctcattttg tattttttgc
     1741 tggtattttc gataccttcg ccattcttca gtacttaatt gaccaatttg tgccaataaa
     1801 tcatccggca tactttttat atcttgttgg cagatcattt gaatcatcat gtctacttga
     1861 tagatttcat tgggcagtaa aaaatgtttt tttgctaaaa gttctagcat cgccaatccg
     1921 catgtctctg gtacgaccct gttcttatat aaattacgca gtttttgcca aaattttatg
     1981 cttttgaaaa aagataattc taactgaatt tcttttgtta agtaagacaa aaatcctcgc
     2041 cagtatgttc ttgcaggttt aacagaatga aatgtatacc agttcccata gtaatagcct
     2101 aatcgttttt tcatttccag atagcctaat tgtaaattta attggttcct ttggctatca
     2161 aaaagcagaa agctgcctag tgtccacaat gtttgacatt tccaatggat aaaaatgtct
     2221 ggcatacgaa tttttttcgc tgggcctggc ccttgcacat ctacgacaaa tgcctctgtt
     2281 gctcctttgt taatcgcaat atcaataggt attttgttgc gatacccacc gtctgcatat
     2341 ttattttttc cgatctttcg ataagccata gcgggataaa atgaagcaga ggcgagtatc
     2401 caatctggta tttcttctgt ttttgtctgt tggatatcag tcactacttc cgctagttct
     2461 ggcagtttag tagacaccgt atataaacgt attttgggat tatgtttgag taaggacaaa
     2521 tccaaattgt ctttgaccat cttttccaat ggagcagaag aaaccccgcc ttcaattagt
     2581 gctgttttcg tcatttggcg tctttctcga tagaagcgtt cacgaaggtc ttcaactgca
     2641 gccatttctg gtaacgcaag cacttgtctt gtcgacagct ttttccataa attcacagct
     2701 tttttcatat ctccttgtaa aatcaatgcg ccgttcaacg cacctaccga ggtacctgtg
     2761 ataatctcaa agttgatatc atgttccttc agcgcctgcc acacaccaat ctgataagca
     2821 ccgtgcgctc ctcctccacc taaaacaagt gctgtatgat agaccagctt tttatttaat
     2881 tgtgtggttc cttgatagcc gtttttatga aaaatacgca accattcttc tgatagagga
     2941 gattgaaata aaaaacaaca gttttcttta ataaaaaaac gagcgcaagc ttccatatac
     3001 cgaaaaaatt ttttccattc aaaagtttca ccttcaatca acagattatt aaaaataaca
     3061 tctcctctac ttttagcaat agtaaaatag acggtatatt ttttcgatac tgctttaaaa
     3121 gcacattgct tttttgcaga acgccaaaaa gcgtctctac tttcttgatg actttgaaaa
     3181 aatggaaggg gttgttttgc ttgctggata ggcgaataca gcgacatttt ctgtgaaaag
     3241 taaacttttt ttatctccat cgcgctctcc tttttcttca agtataccag tacgtcataa
     3301 aaaggtcatg agtctcgtat tcgactttgt agattccata agaaaacaat tcataaaacc
     3361 tcctttaaat aaaaaaatac aaaaatcaca aaaattaatt gaaaatgaga gtgttttcaa
     3421 tgaaaacgtg attttgtaat ggaattttaa aataaaagaa acaagctttt ttaatgcaaa
     3481 tgttgtaaaa taaaagagat taagaggaaa taagaggagg aacatgatga ctgagtcagt
     3541 ttatgtacat attgatacca caagtaatgc tgttttaaca aaagggctga ctgctactga
     3601 ctttgcaaac agtatcgtgc attttcctca aaacttgctc ttgcttgatc catctgcttc
     3661 tgctggagaa tatgaatccc atacagggct gaaagtaatc cgtggtacag aaaatattca
     3721 gcgtttcttt tcctcttctc gtaacaggcg tggattcgat gaattgaagt ggatcgactt
     3781 tactgattta acgatgctga aagaattgac acctttagaa atttcagaat tattatattt
     3841 tggtcatatg aaaacacatc ttcattcgcc gtttttttat aaactacaga ataattttgt
     3901 atacttcgat cttaatgatc agctgaatcg gatttattat cgctatttag atgaatttta
     3961 taggattttt gctagtaaat taagttcgat cttgtcagat aagatcaatg taaaaaaatc
     4021 ttttttcaaa aaagaaacac ctgttgaaaa aatcagtgtg gaattattga aagaaatgcg
     4081 taatttgatg caggaaggga tcattttttc ttttgatcaa gttggtttga tcgatggtaa
     4141 atatcgtatc ccaatctatg tgattgaaga ttatatttgg aaattaaaag gcacccggta
     4201 tcgagaagag gaaatcatcg ctactttaat ctactctgtc accgatcgac actggcaatt
     4261 ggtagaagat gccgatcttt cttatctgcc attgaagtag atctatttct tatcaaaaaa
     4321 taaaaaggaa acaagaaact aggacatgat tctgtctcaa gtttcttgct tcttttttat
     4381 ttacagctcc tgtcgtttat ctggcacaaa aatcgaagga gtcgtttgtt ggatccctaa
     4441 taaaacgatg atcgttacaa tagctgtact caacccgctg gcaccattca ttacgaaaga
     4501 aaagagccaa ggattcatcc cccatagtgc atacgctccc cagaaaacca ctcctgcaat
     4561 aaaatgccaa aaatatctgg aaagtgcgcc aatcaatgca ccaaacacga tgctttttct
     4621 aatttgtttc gtattatcgt ctacatagcc tttttggaca tttgaagcca tgagccctgc
     4681 tgcgcctgca aaagtatagg caatcgggta ctcaatcaac acttgaacga cacttaaata
     4741 ataaacttgt cccaacggaa aatgtaggat gccccaaatg aaacctgcca gcatccctgc
     4801 ctttgtccct cttcttaacg caaaaagagt caatggaatc tgccctaatg aaatagaaaa
     4861 actgctgccg atctggatcg gaatcaacga caacaccatc gctaacgctg caacaatcgt
     4921 tccttctacc caaactctat tttttcccat aaaaaaactt cctcctttga ataaaaaagt
     4981 cacaaaggag gaagcagctt tcgaaaatag tcaaacagct gtttattcac aattcctacg
     5041 ctcgcataac cgatacaggt acgaagggtt tagaaataga ttcaatctca gcccaattgg
     5101 actccccttt gtgagtttat ttattattta ttttttgttt caaacaatgg actaactggt
     5161 ttgttttcat ggatacgttt gattgcatct cccattagtc cgccaacact tacttcatcg
     5221 attttgtcga ttttacgatc ttctggaaga tagatcgagt ctgtaacaac tagacgctcg
     5281 atagctgaat cttctattct ttgtaaagca gggccggata atactggatg tgtacatgaa
     5341 gcatacacac tagttgcacc agcttctttc aaagcattgg cagccaatgt gatcgtacct
     5401 gctgtatcga tcatatcatc gatcagtaca caagttttgc ctttgacttg tccaatgata
     5461 ttcattactt ctgcaacatt tgcttttgga cggcgtttgt ctatgatcgc aatcggagat
     5521 ttcaaaaatt ccgctaattt acgtgcccgt gtgacaccac catggtctgg tgaaacaacg
     5581 acaacatcat cgcctttgat tcctttttct aagaaataat tggcaataag tggcgcaccc
     5641 atcaaatgat cgactggaat atcaaagaaa ccttggattt gaactgcatg aaggtccaaa
     5701 gtcagcattc ttgttgcacc agctttttga atcatgtttg ctactaattt cgctgtgatt
     5761 ggttcccgtg cacgtgcttt acggtcttga cgcgcatagc cataataagg catgactacg
     5821 ttgattgttt ttgcacttgc tcgtttcagt gcgtcaatca tgatcagcaa ctccatcaag
     5881 ttatcattga ctgggctgct cgttgattga ataacataga catgcgatcc acgaatactt
     5941 tcttcaatgt ttacttgaat ttctccatca ctaaattgag taacagatga ttttcctaac
     6001 tcgacgccga ctgctgctgc aattttctct gctaatgggc gattggaatt taacgcaaaa
     6061 atttttaatc ttgggtcaaa gtaatgtttt gacatgggga cctccacttt ctttttcaca
     6121 actctagaat tctacctaat aaatagtagt catatttttt aaataaatca agtgattttg
     6181 caaaagtctt agtttagata agggagtttt tttgcatatc cttctttatt gacttgtctt
     6241 gctctcgcaa ttgccagcgc atattctgga atattgtctg taattgttga cccggcagca
     6301 atcgaactgt ttttagctac ctcgacaggt ccgatgatat tcgtgctaga accaataaag
     6361 ctgtggtcgc cgacagtcgt atgatgtttg ttctttccat catagttgac gaagacaaca
     6421 ccacatccga cattgatttc ttctcccagc gtagcatcac caacataagt caagtgaccg
     6481 actttagttc ctttgccgat ttgagcattt ttcacttcca caaagtttcc gatatggacg
     6541 ttttcgccaa tttcagcttt tggtcgtaaa tgtgcataag gtcccacatc tgcatgtttc
     6601 ttgacatggc tgctttcaat gactgagttt tcaatgacga cgtgatcctc aatcctactg
     6661 tctacgattt ttgaatgtga cccgatgaca caatcagaac caatgactgt atttccttgg
     6721 atttgtacac ctgcttcgat caatgtgtct ggaccgattt ctacgcctgc atcgatgtat
     6781 gtcgttgctg aatcgacaaa gcttacgcca ttgaccatat gcatctggtt aattcgcttt
     6841 ctcatgatct catttgcttt agctaacgcg atccgatcat tgactcccat tgattcttca
     6901 aaatcatccg tttgataagc agcaactgta tggccttctt cttttaagat ttcgatgata
     6961 tctgttagat agtattcacc ttgagcattg tttgttccaa ctttgcttaa cgcatcgaac
     7021 aaagcttcgt tgtcaaaaca gtaagttcct gtattgattt cttgtacaag agcttcttct
     7081 ggtgttgcat ctttttgttc cacgattttt tctacgatcc caatatggtc acggatgatt
     7141 cgtccatatc ctgttgggtt ttctgcttgt gccgtcaaga tcgttgcact tgcatttttt
     7201 ccttggtgat attcaaaaag attgttcagc gtttcagtag tcaataatgg tgtatcgcca
     7261 ctgataacta acgttgttcc tttttttcct tccaagaaag aagcagcttg caaaacagca
     7321 tgtcctgttc ccaattgttc tgcttgtaac gcatatttac tgcgttctcc tagttgtgct
     7381 ttaacttgtt ctgctccgtg tccaacgatc gtaatcactt catctggttt cgtttcactg
     7441 acccgattaa tgatatgttc taccataggt ttaccagaaa cgggatgtaa aactttatat
     7501 aattttgact tcatgcgggt acctttccct gccgccaaaa taattgcata acgtgcgtcc
     7561 aactgcgtca ctcctaaata tagtttgctg atttcagttt atcccagtat acccattttt
     7621 tcaacaaaac aagtgatttt cttttatccc agcgttttct ggataaaaaa atagatagac
     7681 cataacgggc ctatctattt ggtaaccggt gctctcctgc caactcctcg gtcacaagtc
     7741 acactactca taaaacatga aaagctgttt tttgaaatcg tttcttgtga cttagagtta
     7801 aacggtaggc ttacaacctc ttcattaaac gtttttcaat cagctgacct tcggtattag
     7861 ctcaataaac ggcaaaatat gaggagcaat ttttccgttt attgagctaa tactcaggac
     7921 aggacgctga tttcacaacc tctagataaa cggtgttcaa aagccagttt ctcggtatta
     7981 agccaaattt atgaaaaaat gtggaaagcc attttcacaa aatttttctt actactcgaa
     8041 actaagcagc tttttcacaa cctcttattc tgaaaaataa tttcctggca caaccgtaat
     8101 atttttcgtt tgagtatcta catctttgac ataaagcagt gacgtataat catcgatggc
     8161 gcgatgaccg ttgaattttg attcggcaaa tacagtgatg ccaacaagtt ctgattcgaa
     8221 ttcttcaatc aagctcttca ttccgttgac tgttccgccg cctttcatga aatcatccac
     8281 tacaaggaca cgtgaaccac gtttcaaact tctcttagac agttccatct tttcaattct
     8341 ttcagaagat ccagacacat agttgacact tactgttgat ccttctgtta tttttgagtc
     8401 ccggcgtaca ataacgaatg gcgcattcag ataataggac acagcttggg caataggtac
     8461 gccttttgtg gctacagtca ttacagcatc gattttttca ccaaggtatt tagaagcaat
     8521 gattcttcca acttgacgca gcagttcagg ttctcctaac aaatcagaga gataaacata
     8581 tcctcctgga agcagacggt cttgttctga tagacgttct gctagagatt caatatattt
     8641 tttcgcctct tcatatgaaa tttcagggat gaacaataca ccacctgcag cacccgggat
     8701 tgtttccaag gttccatacc ctcgttcttt aaatgttttc ttgatgattc ccaaatcttc
     8761 actgatagaa gatttagcag attcataacg ttcggcaaag cttgttaagg aaatcaattc
     8821 atgcgggtga ttcaataaat actgtgtcat gtcaactaga cgttcactgc gacgtacttt
     8881 cacctattcc aactcctttt aagaaatttt atcgttttac attatataag tttttcttca
     8941 aaaattcgag cattttatga aaaaataaga aaatagttcg gtatttatta aaataaaaag
     9001 aagcctataa aaaatttttc gtttttataa ggcttctttt ctttataatt tagttatttt
     9061 ttcttctgaa ggcaaccaat attcgtttga tgatatttac aatcaggaac aaagcaataa
     9121 agactaatgt gattgttgct cctggaggtg tatctagata aaacgagcta gttagtcctg
     9181 acagcatccc tagaaatcct acacaaacac tgatagcaat cacgacattg aagcttttgc
     9241 ctaatcgcat accgattgct gcgggaagaa ccatgattgc ggatatcaaa agtgcaccgg
     9301 caatcgggat catcacagca atagccacac cagtaatcac attgaacatc atcgacatca
     9361 aatgaacggg tagcccatcc acgtgggcgg tatcttcatc aaaagtcaga acatacatcg
     9421 gccgtttgaa taaaaagaac aatataccga tggcaacgaa taagattcct aaaaagatga
     9481 cttgctccca tgtaatggtc acgatcgaac caaacagata ggattggata cttgttgctg
     9541 aattccctcc gctcaaattc atcaatacta acgctagcgc caaaccacca gccattaaaa
     9601 tggcaatgga gatttctgaa taggttcggt agatcgttcg cagatactcc aatatcacag
     9661 ctgctaatac aacgactagc atggtcgtaa gtgtaggatt aaggttcaaa aagaatccta
     9721 acgctacccc tgctaaagag acatgagaaa gcgtatcagc catcagcgat tgtcttctga
     9781 tcactaaaaa cacacctagc atcggggcga ttccggcaat gaagatagcg gcaagaaacg
     9841 ctcttctcat gaattcatat gaaagcaacg ccattgagaa tcctcctttc tcaccagtcg
     9901 gatctgtctg tccgcatact gtttgatatc ttcatgatca tgggtgatca ttagaactga
     9961 tttcccatgg acatgcgcac tatgtcggag aagacgataa aattcatttc tggattcttc
    10021 atccatacct gttgttggtt catcaagaac aaataagtca gggtcagtag caaaaatacg
    10081 cgctaaactg attcgctgct tttgtccgcc agacaattca cctattcgcc gatttcgcat
    10141 atcccacatc cctacagctt ctaaagcacg ctgtacatgt tgatgatctt tttcagagag
    10201 acgcttgaac cagcggcctc ttggatatct tcctgaacgg actaattcga tcaccgtact
    10261 aggaaaacct gcattgaaag atgcaacttg ttgaggaata taaccgatac ttaatttttt
    10321 tccttcttga tttttctcag caatctttat cattcctttt gaaggtttca gtaatcctaa
    10381 cgatgctttc accaaggttg acttggctgc tccattttct ccagttaaaa tgacaaattc
    10441 acccgcatct acatgataag agacatcttc tagtacaggt tcatcatcat agtaaaaggt
    10501 caaatcagat atttcgatat aacgcacctt acaacctcca ttctaaaact taattgatac
    10561 tttcttttaa agctttcaga tttttttcca tgacagaaat ataattttcg cctgctttga
    10621 tttgttcatt agtcaagctt tctaaaggat tcaacacttc tagcttcact cctgtttcat
    10681 tcgacaatgt ctcagctacc ttcgaagagg cattttcttc aaaataaatc actttgatgt
    10741 tgtttttctt cacaaattct tttagctcag ctaagcgact tggtgtgggt tcctgatctg
    10801 gtgaaacgcc cgaaatcgct acttgtttta agtcgtattg attcgctaaa taagcaaaag
    10861 cagcatgctg agtgacaaat gtgcggtttg ttgcatcttt tagctcatcg gagtattttt
    10921 gatccagtgc ttcaagcttt ttgatataag catcggcatt cttcgtaaaa gtttcctttt
    10981 tatctggata tttttcgcct aattcttcag caatcgttct gacttctttt atagctaata
    11041 ccggatcgag ccaaacatgt ggatcgtatt catgtgaatg accatgccct tcttctgatt
    11101 cttcatgttc gtctgcttct tgcgattcta aacggtcgat tcctttagct gcttcgatca
    11161 tcaaggtctg tttgctatcc actgaatcct ttaacgaatc cacaaaaaat tccatgtctg
    11221 aactattata cacgaaaaca tctgcatcgg aaatttctgc tctttctttt gcacttggtt
    11281 cgaaatcatg cggctccgtt ccagcaggga tcaaaagttt cacgtttcct tcatccccta
    11341 cgatctcttt tgtaaaatca tacatcggat aaaaagtcgt aacgatcgtc aaatcctctt
    11401 ttttgtctgc ttccttgttc gtatttccac atgctgcaaa cagtaaagca cctatcatta
    11461 ccgtagctgt caaaagatat tttttcattt atatgctcct ttcaatgaac aaatcggaat
    11521 tttacgattt attaacgtga actaatgtat caaaataaaa aaacacagtc aatagaaatc
    11581 catcaatttc tgatttaagc atgtatattc ttgattaaat cgtaaaatgg atgagttgct
    11641 gctcatatct agccatttca ctacaataaa aaactgaaga ataccatttt aggattcctc
    11701 agtttttcat cacctatttt acttcttata ttttattgca gggttcgtac taaataaact
    11761 tcctcacaaa aaccttttaa cccattatat actctctgcg ctcttgaata atgttgacac
    11821 aaggcaaaaa cggttggtcc gcttccactc atcaatgcag catctgctcc gtacttgatc
    11881 atacgctctt tgatttgatg gatgactgga tgccgctttc ccgttatatc ttctaaactg
    11941 tttcccattt ttttgatcat ctgctgataa tcttgctctc ggatggcttc agcaagtccg
    12001 tggatgtctt gatgttggat ggcttgcgta tctacttctc taaacactgt acgtgtagag
    12061 acactcattc ttggtttgac caacacaacc cagcactgtg gcatagaagg taatacttgg
    12121 atttcttccc ctttgccacc gacaaatgcc gtacttccgt agacacagta aggaacatct
    12181 gtaccgactt ccaaaccgat ttctgccagt tcttctaacg aacagcccag attccataat
    12241 tggttgatcc ctcttagagc agctgcacag tctgtacttc ctccgcctaa tccagctgct
    12301 actggaatat tcttcttaac aaagatcttg acaccggttt tgatattgta tttatttttt
    12361 agcaataaag cagcttgata aacattgttc cgttcatcta ccggtaaaaa tgctttattt
    12421 gtttctacaa tgattttgtc ttctgttatt tcttcaaaaa atagatgatc tgccaagtct
    12481 acgctcgaca tcaccatttc caactcatga tacccatctt gccgtctata taatacatcc
    12541 agtcctaaat ttatcttggc tggcgctttt tcaatcaatt ccatcctctc acccattcga
    12601 aaagtctaag tcgcaagtat tctatcatag ggaaaaataa aagtatagct tatgtctgcc
    12661 tagtggttga ttttgtcatc gtttcaacag ctttcacaga attttctctt cataatccaa
    12721 acaagttcta gtgattctta taattctgtg agcacttctt ctgccaaact cggaacattt
    12781 cctttttctt ttcctatcag actgagtagc tgcatggtag caaatccgaa attacttcct
    12841 ttcctataag caaaataacg tccttcccaa tgatcgacat attttaattt cttttcataa
    12901 gcagactgga aggaatagaa aaaattacca taattatata cgatatgcat gactttttct
    12961 tgaaagaaag aaaaatctgt ttctccaaca ttagctaatg gagctaagcc tagattggct
    13021 tccgagtagc ccattttctc gtatacaata aacagattgg ctaacagata gtcagctaat
    13081 tcctcagatt ctttaggtaa gacccgcaac aaatcatatc ccgcctgctt cttcgtcatc
    13141 ggctgagcgg tgatgaagcc aacgactttt tgatctttac ggacaatacc gacaccgcta
    13201 gataatacat atgatttatc aaatcgtccc acagagaagt atttttctcg tgcaccttga
    13261 agccattttt gtgaaacttc atttacagct tgatgtaatt cttccggcag ttgatcgtac
    13321 caagtaaaat ggtatccttc tttcatcaaa cgttgatatt caagttgctg actcagccga
    13381 gacaagtctt ctgttgctag atcaacaatc cctgcttcac ctactttcgt gaagtgaaaa
    13441 cccaattcat gaagcatcac tacgtagctt tctgatatct tataaaacgc aagctgatag
    13501 cctaaacaat ctgcttgttt cataaactga ttcgttgctg cccgcatcat tttaggattg
    13561 ccaactggat ctcctaaaac aaagcatttg tttcctttga tctgataacc aaaaacgact
    13621 tgatcttggt cgtcttcttg gtaataaaaa taactgtaac ctgacaagcg aagctgatgg
    13681 cttgtagctg tgcctccgta tgtttccaat aaacggtcaa aacggtcttt ttcgtactca
    13741 ctgccaagct tcgtagtatc ttcagctaaa tattgataaa gcgccactaa agctagcaat
    13801 gagatgccca aaccaataag ccctgagaac cacacatcat ctgaaggaaa caaaataaaa
    13861 tgatttcctg ttattcgacc gactaaaaag cgtccgctgt gatagcctgc aattgcgtaa
    13921 acgataaaca aaaagccgaa caagctagca tcaaagatta tagctcccca agaataaacg
    13981 aattttgttc gataaaattc ttttctggat aaccacacag ctaacagaat caagacatat
    14041 accaatatca actgccaaga taacgtacgt gtgattgtat ttaaaatacc aaaagatagt
    14101 aaagcaatcg taggcagaaa tgcctttttg acttttactg aaagtgctct agcaaggccg
    14161 agtaataaaa agccaaccaa tagattcact gtctgatcta aaaaattgaa tgagaacggc
    14221 aataatactt gaaatagccg actgattgca gacagattag tgattgttga tagaagtacc
    14281 atcatgatcc ccgcaaaata gacagcactt acgagcacga tatgcgcaac cttttggaaa
    14341 aacagtcgcg gaatgttatc taaaaatcga ttgattttga ctcctgtatg tgtgatgaac
    14401 aatagaagtc ccgtcataaa aggtagaaca taataaaaca accgataata taatagccaa
    14461 actactgcta catcttgccg aacaggcaat tgactcattc ctaagatcat caaaacgtca
    14521 aaagtcccca ttccacctgg gaccatcgtc agcattccta tcaatgtagc aatcatgaac
    14581 ataggataga tcgaaagcat cgaaatatct attctcatca acttgccgat gatcaaaaat
    14641 accgcaaggg ctcccgtcca ttgtccaaag gatgccagta gcagaccaag caagcctttt
    14701 ggataaaact cgaagaacaa tgtctttctc tttagataag caaaaaagaa aatgactggt
    14761 gctaaaaaac taccgccgaa aagccagatc caatagcttc gaaaaatact ttctgactga
    14821 ataaaaaaga catcaataaa tgtaagaaac gaccatacag acaaaccagt cagcataaat
    14881 agtgcgactt ttgatacagt ggctaaaacc atttttctat ttgtctgctt tccataaaaa
    14941 ctagcccgca gacttgctcc taccacacca ccaaaaccgg cgagattgtt gatcgtgttt
    15001 gttacccacg cagcaagaag aaactctttt ctttccattt ttggttttcc ttgtttttct
    15061 aagactctga tcgtcaccca atcatacaac aacatcggag tgacacccag cagtccagcc
    15121 agaatcatga gcaggatcgt catgcggctt tgttgtccca tcctttgcca aatatcttgc
    15181 caactcatgc cattagcaat atttgcgact tgatttgcca caaagactaa cacggagccg
    15241 aaaaaaatca gttttaaaat cagactatgt tcctttatcc attgcagcat caagtatcgt
    15301 ttatttttca cattttccca ttcctaactt gtatactttt gtgtcatacc ccaatgttat
    15361 cttatttatt ttaatttttc cactttagac ctgttctttg cttgcgatga tagaaaaaga
    15421 aagatatcct aatgctaaag gagaggataa catgaaagta ggatttatcg gcacagggaa
    15481 tatggcacaa gctattattg atggtttatt aaaaaaagga acagtctcga aagaagaggt
    15541 gttcgtttcc agtggacatt ttgaaaatgc acaaaaattt gctgctgaaa ctggcgtcca
    15601 tgcatgcaaa agtaatcagg aagttgcatc acaatcagat atcgttcttt tagccgtgaa
    15661 accaaaaatc attgaaaaag tattggaaga actaagagaa tatagccaga aagtcttatt
    15721 catttctatt gcttcaggaa aatcattaac agatttagaa acagcgcttg aagatcctca
    15781 ggcctccatc gtacgtgtga tgccgaatgt caatgtcagc gtaggagcag gcgtttctgc
    15841 gatttgcaaa aatgaagctg ccacggagga acagcttcag caagctacga tgatttttga
    15901 agcaatcggc agcgtctatc ctttagcaga atcagatttc agtacattca ttggccttgc
    15961 tggcagctca cccgcattcg tttacatgct gatcgatgcg atgggacgga ctggtgtact
    16021 gaatggtttg tccaaacaga cagccactga gattgctgca aaagcaatta tgggttcttg
    16081 tcaaaaattc ctttcaagtg ataaaaatcc atgggaactt gtagaccaag tttcttctcc
    16141 tggcggtaca actgttgcag gtgtagttgc cttagaagaa gcaggattca tcccagcaat
    16201 catcaaagga atcaatacga cgatcgagaa agatcttgag atgttgaata aaaaataatg
    16261 atagcaatgt tttttcgtgc cttacaaaaa aagaagagct gtggcttttg ccgcggctct
    16321 tcttttgtat tttttattat ttagcataat cagttgcacg agtttcccga ataacgatta
    16381 ctttgatgtg tccaggataa tccagttctt cttcgattcg tttacgaata tcacgtacta
    16441 aacgaacagc gtctaaatcc gagatttctt ctggcttgac cattacccga acttcgcgtc
    16501 cagcttgaac tgcgtaactt gattctacac cggcgaagct gttcgaaata ttttccagac
    16561 ttcttaaacg acggatgtag ttttctaatg attcacttcg cgcaccaggt cttgctgctg
    16621 agagcgcatc tgctgcagct acaaggacag agataacaga agtagcttcc acatctccat
    16681 gatgagaagc gatcgcgttg attactactg ggttttcttt gtacttggca gctaattccg
    16741 caccgatctc aacgtgagat ccttcaatct catggtcaag tgctttccca atatcatgga
    16801 gcaacccggc acgttttgct aattggatat cttcgccaag ctctgctgct aagataccag
    16861 ctaattttgc aacctcgacc gaatgcttca agacgttttg tccataacta gttctgaatc
    16921 gcagacgtcc gatgatcttg attagatctg gatgaagtgt atgagcaccg acttcaaacg
    16981 ctgcctcttc cccgtattcg cgaatacgtt catccatttc tttacgagat ttctcgacca
    17041 tttcttcgat acgcgctgga tggattcgtc catcttgtat cagtttttcc aaggtcatcc
    17101 gtgcgatttc tcttcggatt ggatcgaatc cggaaagaac aactgcttcc ggtgtatcat
    17161 cgatgattaa atcgatacca gtcagcgtct caagcgttcg aatattacga ccttctcgtc
    17221 caatgatacg acctttcatt tcatcattcg gaagggtaac gactgaaaca gtcgtttctg
    17281 aaacttgatc tgctgcgcag cgttgaatcg ctaatgataa taagtttttc gctttgcgat
    17341 ctgcttcttc tttggcacgc tgttcagatt cttttaccat tagagttaac tcatgattca
    17401 gctcttcttc agtcgatttc atgatgacat ctcgtgcgtc ctcttttgat aaaccagcaa
    17461 ttttttctag ttctttttgt tgatcttcaa tcattttttc aacgtctttt tctcgctctt
    17521 caattaattg ctgttttgaa ctaagtgctt cttctttact ttcaagtgag ttctcgcgtt
    17581 tttctaacga gtcatcttta cgattcagcg tttgttcgcg ttgaatcaaa cgattctctt
    17641 gagattttaa ttctaactta ctttctctca gctcactttc aacttcagaa cggtatttct
    17701 gattttcttc cttagcttct aacaatgctt ctttttttag agtttctgct tctttttttg
    17761 cactatcgat gattccagca gctgatgatt gtgcaccagc tatttctttc tcgtgacgtg
    17821 actttgcgac cataaaccct aaaccaagac cgacaattaa accgatgata gcgaggagaa
    17881 tgttgaatac cataaaatcc acctccatac tatctttttc atttttatca tctatacagc
    17941 ttctatgata aattattcta aactcgtcaa tatgcatctt cgcatatatg tgtacaaaaa
    18001 acatgcacaa ctttattcta atgtttgtac cccgtagtgt caactttaaa taaacaaaga
    18061 aacggctttc tacttattca ttaaacgatg gtttttaaaa taaatgacac tagtttcata
    18121 taggtaaacc tttaaattga gaaacttttc tattaaatta ttctttgtag atgaacagat
    18181 atttttattt tatgtaccca ctcgtataat taaataactc acgatttctt tattcaataa
    18241 aaaaacggca ggtcaaggag agtacctact cttcagacca gccgtttttg tttatcataa
    18301 tttttattct tctactaaag gcaattcttc ttgtcctttt tcatcttctg ggacagcgac
    18361 ttcttcacca ataccataag ctgctctaac tagagcagaa acttctgcca tcatttcagg
    18421 atgattagcc atatagattt tagcgttttc ccgtccttga ccaatccgat cttctttata
    18481 agaataccaa gcaccgcttt tatcaacaat gtctttttct actgccatgt ctagaagttc
    18541 tccttcttgt gagatcccta aaccatacat gacatctact tcagcgattt tgaaaggagg
    18601 tgctactttg ttttttacga ctttgatctt tgtacggtta ccaacaatat ctgtaccttg
    18661 tttcaattgt tctgcacgac gtacttccaa acggatcgtt gcgtagaatt tcaatgcgcg
    18721 tcctccagga gtgatttctg gattcccaaa catcacgcct actttttcac ggatttggtt
    18781 gatgaaaata gcgattgttt ttgttttgtt gatcgaacca gagagtttac gcaatgcttg
    18841 agacatcaaa cgtgcttgta acccgacatg tgagtcaccc atttcgccgt cgatttctgc
    18901 tcgtggaact aaagcagcaa ctgaatcgac tactacgata tctacagccc cacttgatac
    18961 taaagcatca gcgatctcta gaccttgttc tcctgtgtca ggctgtgaaa gaagtagttc
    19021 atcgatattc acacctaatt tttgtgcata ttgcggatct aacgcatgct cagcatcaat
    19081 gaaagcggcc gttccgccat ttttttgtac ttctgcaata gcgtgtagtg caactgttgt
    19141 tttacctgaa ctttcaggtc catatacttc gatgatacgt ccacgggggt aaccgccgac
    19201 acctaaagcg acatctaacg caagagagcc acttggaatt gtagagattt gttggtcgat
    19261 tttttcgccc aatttcataa tagagccttt accatagctc ttttcaattt ttttcagtgc
    19321 agcatctaag gctgctttac gatcatctgc caatacgata atcctcctta tatttacaaa
    19381 tcagagcaac atttcattat ccttatcata tcttttttag tgaaaaaaag caagaaaaaa
    19441 ccgaacaaat attcgcattt atcattttct taaaagctgt tttctcaaaa gatcaaatcc
    19501 ttgcataacc gcattatatc tgatagcagc acgatctctg gcaaagtgat atttttccga
    19561 aaccacgccg tctttagatg aaatagcgat ccatactgtt cctgcagatt gaccttctaa
    19621 cgtgtccggt ccagccactc cggtgaaagc tacactgtaa tctgttcttg ctatctcacg
    19681 tgcttgaatg gccatctgct ccacacattc tttgctgact gttccatatt ctgctaatag
    19741 ctccggatca atctccagaa aaccagcttt tgtttggagc gagtaggtaa cgaatccgcc
    19801 tggaaatact tcagatacac cagcaatgtc gcctaatgcg gcttggaagg cgccggctgt
    19861 caaactttcc gctgctgtta cagtctgctt gttttctttc agtagttcca ctacgacttt
    19921 tgctagcgaa ttatcatcgc cgtatccata aaaatattcc cctactcgtt cttggatttt
    19981 ttcttctaat gctaaaagag cttgattccc tgcctgaaca tcatttgttt tcactgtcag
    20041 tcgtaatgtc acttcatttg gtttggcata tggtgcgatc gttggattga tctgtgtctc
    20101 aatcagatct tttagctcag tgaccagtcg cgattcacca atcccataaa agcgcaaaac
    20161 tttagaaatt agtttttctt cagaaggaaa acgttcctct agtaaaggac gtacttgttc
    20221 cacaaacatt ggtttcaact cattaggcgg accgggaaga aggatatacg catgtgtatc
    20281 tgtttgataa aaagtcccta aagcaagccc tgtacgattt ggtagaggaa ccccgccttc
    20341 gataatctgg gactgttgca gattgttttt ggtcattttt cgatgggttg tttcaaaata
    20401 tgccaataat tttttgtatc cttccgtatt ttgtatgaga gacttaccga ggtgagccgc
    20461 agttgcttct tttgtcaggt catcttctgt cggtcctaat ccgccacata agagtatgag
    20521 ttcacttctt gtttcagcta gagcaatcaa ctcttctaaa cgctgctgat tatctcctac
    20581 aactgtttga taataaactt cgatacctag atcagctagc tgttctgaca agaaagtggc
    20641 attcgtattc acgacttgtc ctagtaaaag ttctgttccg acagctatta tttctgcttt
    20701 cattacttcc cgctccctta tatagtatac gctgtatttt tatatttttt tatttaaaaa
    20761 gagggcaagg agctgtgaca aaaatcttgt cacagctcct tgttccaaat aaacagtgtt
    20821 ctcctgccaa aacctcggtc ataagtcaca atatacataa aacatgaaaa gctgtttttt
    20881 gaaattatcc cttgtgactc agagttagac ggcaggctca caacctctcc actaaacgat
    20941 acttacattg atcctttgaa cacaccgctg tttttgatga agtaatccac acctgaatag
    21001 atagtaaaga tcagacaagc ataaagcatg atttgatcta ctggaatacc gatcaggctg
    21061 aatgggatat tattgataaa cagcaagata atagcaacca tttgtgtagc cgtcttgact
    21121 tttcccggcc aagctgcagc catgacttct ccatgttcga caagtagtaa acgcaagcct
    21181 gtgacggcta attcacgaca gacaatgatc gctactaccc aaccaggggc ctttccttgg
    21241 tcaaccaaca tgataaaagc agtcataact agcattttat ctgccaacgg gtccgcaaac
    21301 ttgccaaaat tagtgacaag gcctcgcgca cgggcaattt ttccatctaa ccagtctgtg
    21361 atactagcta aagcaaaaat aactgcacct actagctgtg tgacagccag tgtggtgtct
    21421 cctacgttaa attgtcccca atctaaaggt aaacctacaa ccaaaatgaa aatcgggatc
    21481 atacaaattc taagtacagt taatttattt ggtaaattca cactatcgac tcctttcttc
    21541 cctattctac gtgactatca gcgaagtttc caccgatatt atttactttt ccaaatgaat
    21601 ttattcaaag gagtattttt attgaaattg atctttttga attaacgaag aaggaccgcg
    21661 acacagattt gtcacgatcc ttctttttta tacctacaag taaacagatg cgtaaactaa
    21721 tttatacgat cattctgcgt attgaagagt aaggttcaca ttttttggac tctgattgtt
    21781 ttcccctgga ttaactggta cggattctcc attcgctttg atcgttgcat tgcttgctgc
    21841 accaatcgtg atggtcgcat ttgttgctgt ttccggtaac acggtactct gtgtttcatt
    21901 tgctgccagt gtcccttgat aaacataggc attgtctact agcacaccta accatacacg
    21961 attgacagca gtaaattcaa gggttacagg cttggtagcg tctgtgatat ttactgcgat
    22021 ggcactgcca gaatcttctc ctgtagctat tgccattttc ttttcttcac ttgattttgt
    22081 tgttgattct actgtagaag actctttggt ctgcgtgctt tgctctgagg aagaggactc
    22141 ctcgactgat ccttctactt taagcgaaga agctgtgtct ccgattattg gatcagcttg
    22201 acgatcttgc caagtcatat agcccacgac aacgacaatc gccaaagcaa ccaatcctaa
    22261 taaaatgaca ggaagacttg tccaaaagcg acttggatgc gattcttcct gatgcattgc
    22321 ttttctagaa gtacttactg tttcaggctg cggacgttca gggaccgatc ctgtcaattt
    22381 gcttttccca tcaaaaacat cgactaaatg gtctccatct tctcctacag cttcagcgta
    22441 ttgccgaata aatgcccgca cgtaaaattt accaggcaat tggtcaaaat catcattgtc
    22501 gattgcttcc aaataacgtt tttgaatttt tgtaatctgc tgtaattcat ctaaagatat
    22561 ttttttattc aggcgtgctt gccgtaattt ttctccgatg gtttcaaaag ccactcgttc
    22621 atcttctcca gtctgtttga ttctccgaag catctgctgt tgcaacgaaa gacgttatgt
    22681 ttgggtgctg tgacaaaagt catgtcacag ctcctttttt ccgaataaac attgttctcc
    22741 tgccaactcc tcggtcacaa gtcacaatat ccaataaata taagaagctg ttttttgaac
    22801 ttgttccttg tgactcggag ttaaacggca ggctcacgac ctctttctta aacggtgttc
    22861 aatcagctgt tcctcggtat tagctcaaaa accggcaaaa tataaggaga tatttttccg
    22921 tatgtttctc taatactcag gtcaaaacgc tgatttcaca acctcttcct taaacggtgt
    22981 tcaaaagctt gcatctgcgg taataagtcc aaccaagtta aaaacattaa gaagctgttt
    23041 ttacttggct gttcttatta cttgatgcag ggcagctttt tcacaacctc ttggtacacg
    23101 gtgttccaga agtagcttct tcggcaataa gccgaaatat cacaaaaatt tgagaagcaa
    23161 ttttcgtaaa ttccttctta tttcttgaag ctgaccactt ctgtcacaac ctctttgatt
    23221 acttcgtttg attttatttt aatataagtt gattaaaaga gagcatgatt tgttttattt
    23281 tctcactaat ttttccaaca caactaagaa taccataaaa gctgattttg gaggaggttc
    23341 ctactacaag tctaaaacga aatttaagac ttttcctcat aaaatactgg tttattttgg
    23401 tctcatgtaa aactcgctga aggcctcttc acttataaat gcttccccag ctgccagtac
    23461 gtctttcatt tggatcgaat cgatgatttc aggaagatca aataaagttc gatcgccaaa
    23521 taaactttgc gtaaattgat tggcaatata ttcgatcgaa tttaatgatt ggaaatattg
    23581 tccaagcatt ttcttcttca gcaaatcgag atttgtttct gacacttccg gatcatcagc
    23641 gaatccaaga atgatttctt tgactttttc tgctgctttc tctggttcgt ccgtatctcc
    23701 gctgaagtcc gcaaagtgaa attcacgatc caagctgaat tcaaaaccaa agctgtcatc
    23761 gataattcct tgattgtaca tcgctagata gtttcgagaa gtattgccta aaatcatttg
    23821 gaacaacaga ttgattgctg ttttatagcg taacagttct gttccttctt gcggcaatgt
    23881 gtctaatcct ttaataccaa gtacaaattt atctcgtgta atggctgctt ccaatgcact
    23941 ttgtttgatg atttcttttg tgttttcagg gaaataacgt acaatttctt gctttggagg
    24001 gaaatttttt gcttcttggt tttcccgaat aagtttcatc aatttctcag gctccatctt
    24061 accaactaca aataaaacca tattgcttgg ctgataaaac gtccgatagc acgtatacaa
    24121 gtcttgagct gtgattttgt cgatactttc aaccgtgccc gcaatatcga tatgcaatgg
    24181 gtgtgtagga tacaagttat ttagtatgcc aaaaaacatc cgccagttag ggtcgtcttc
    24241 atacatttgg atttcctgac cgatgattcc tttttccttg tttacagttt cttctgtgaa
    24301 gtaaggtgct tgtacaaaat cgatcagagt cgtcagattc ttttctacct gatccgtcgt
    24361 agaaaacaga tagctggttt tcgtaaaact tgtgaaagca ttggcggaag ctccttgttt
    24421 cccaaataat tgaaagacat caccatcttc tttttcaaac aacttatgtt ctaaaaaatg
    24481 ggcaattcca tctggaactt tcaccttttc tttttcacca tagggaataa attcgttatc
    24541 gatcgaacca taattcgtac tgaacaaacc atatgtcttg tgatagtcat ttttaggcaa
    24601 caaatacacg gtcaaaccgt ttggcagtac ttcatgataa agtgtttcat tgatttgctc
    24661 atattctgtt ttattcattt gcatttcctc ctgctaaaaa gaagattgcc tgcaattcga
    24721 tttgctcagc tacttgttgt atctctttga tcgttacgct ctccatacgt ttcaaccatt
    24781 cttcatcaga taattttgtt tccggcagcc agctgtccaa aaaagaagct tcgattgccg
    24841 cttgcggaga gtctagagaa agcagatatt ggtttctcag cattgctttt gtctgagaca
    24901 gttccaactc tgttatttca ccatttcgca aactttctaa ttgctcgtga atcagatgaa
    24961 gtacttgatt tcggttcttt tcatcgatac cggtttggac actcatgaat cctcggaacg
    25021 tatccacgct actagaggca taataagcta gactttcttt ctctctgaca ttcatgaaaa
    25081 gtttagagtg aggaaaaccg ccaaataaac cgttaaagac cattagcgca aaacgttctg
    25141 gttcatcgta atacacattt gtctgataag ctaggttcag ctttgcttga acgattggct
    25201 cacgtacttg tcgttccttc acgatattca cttgaggttg ggtataaaac agatctggat
    25261 aaactgtttc ccgcgactca aatggtaatt gcccaactgc ttcagctgct ttgtccggat
    25321 caacatcgcc gacaacaaaa atgtcgattt gatcatttgc catcatttct tgatagtagg
    25381 acgctagcga actagcagtg atcttgtcca aatcttcgac tacgcccaac cctgggatct
    25441 tttgttccgg gctgttttca aaataaagtt cttgcaaggc ataggaagca aaagtttgtt
    25501 tatcttcctt caaactttcc aaatatagac gcagattgtt cttttccaag tcaaacgtca
    25561 actgatcaaa ctgatgattt ttaatatttg gataaaataa aacctctttt aaaaaatcta
    25621 ccgcttgaga aaaaaggttt ggatcattga catattcacc attcacaaaa ctgatccctg
    25681 cgtttagcca atgtaaattt cctttttttc taactgataa tccaaagctt gcgccataaa
    25741 gctctgcaag ttgcgcactt aactttgtct gatccggata attcaaacta tttgtttcca
    25801 acatgctgct gagaagtgaa cgtttcgtga tgacttcttg ttgcagacgc gcagtaaaac
    25861 ggataaaaat ccggatcgtt ttgtattgtt ttgttggtaa gacatgaaga ttcacgcctt
    25921 ctgccaattg atacaccata tttatatgct ccttttcaca gttgattgcc cgcttactct
    25981 tttaatgggt caacctgcct tttttactta ttcctctgct tgaaatttat aagttcaggc
    26041 aattcgccgt tttttctaaa tgatgttaca ctttatagta tagcatagat gttttttatc
    26101 aaaagaaaca gacggctaaa agcgtatatt gtttttttat tttttatttt tcgatatact
    26161 aaagacaaat aaaagaaggg agggtcattc atgatcaaag aattcaaaga gttcatcatg
    26221 cgtggagatg tcttggatct tgctgtcggc gttgttattg gtagtgcgtt tacaagcatc
    26281 gtaaaccaag tggtgcaagg cttgatcaca ccactaatag gttggtttgt cgcaatgatc
    26341 acaggtactt ctgatttaga aggagcactt tcaattcttg actggtcgcc gacaaaaggc
    26401 gtcacatttg cgtttggtaa cgttattagt gctatcatta catttctgat cactggtttt
    26461 gtcttattct tagttgtcaa agcggcaaac cgtgcgaaga atttacgctc caaagaagag
    26521 caagtggaag tggaagaaac tcctactgca gaagattatc ttagtgacat acgcgatctt
    26581 cttgccaaac aagtggcaga agacaataca catccagtag agcaaacaaa tctttccgat
    26641 acttctaaat aataaagaat ctaaaaaaaa gaaagccgat tttcagtgtc ggctttcttt
    26701 ttttagattc ttaacttgct acttgttcct ttttcatgtc gatatgtgga atatcatctt
    26761 ccaaatacac atctgagatt gccttgaatc caaacgactc ataaaaagct tgtaggtatt
    26821 cttgtgcgcc gatcacgatt ggtttttctg gaaaattttt ctggatcatg ttaatcgttt
    26881 cttgaacaat ctttcttcct aaaccatctt tacggttgtc ctgatgaaca aggacacgtc
    26941 caaaatggat actctccgct tcttcatata ctcgcgtgta ggcaaggatc ttcccatcag
    27001 tatcttgaaa aaacgtatgc caagcttgtc catcaatgtc atcaacttct tgataaggac
    27061 actgttgttc cacaacaaaa actgcgattc gttctttgac gatcgcgtaa aactctgctg
    27121 ttgacaattc ttcaaatttc tttacctgat attccactaa gcaaacgccc cctgcttttt
    27181 tattcttagc ataccgattc gcacacaaaa aagcaaacga accttacgaa tctcaggctc
    27241 gtttgctttt taaactgctt cagttaaaaa ttcgatctca actgtccgag taagtacatc
    27301 tgaatagctg taagatactc gttcaaaaga attttcttca ggatccaaat caacaacgaa
    27361 tactgaagga taggtttctg ttaaaacgcc gcggcgttct gtttgacgct ttcttcctgt
    27421 ctgagcaacc aacatgattg ggctgccgat acgaccttct aaatctttct tgattgaagc
    27481 taaagttgtt ggcatacagt tcacctctac tatcaactat accacatatt tttaaaattt
    27541 tcaagtttac cataaaaaaa aagaaatgca ataaaaataa ataagaagct cattaagatt
    27601 tttctaaatt attcctcatt ataaaatttc aagtgttttt ttattttgag ttttactctc
    27661 ccgtaagcgc tcattacttg cttgtgatcc attgctaaac attcagccat gtctacaaaa
    27721 tcaacgcctt gcatataata atgaaaaatt ttagcttcta tttttgaaaa ctggatttcg
    27781 caattttcga ttgcttcttt taataaaaga tgctgaatcg ctaaaggttc ttgcaatgtg
    27841 atctctgcta aaaagtctgg tccttctgtc tctatttttt ggtcgattga gacttcatct
    27901 ttttgatcac gacgcttcag cgcgttctgc ttcctcaaca gagaatagat ttgattgctt
    27961 ataatgcttt tataataact tccaaagcta acacctttgc ttttttcgta agttctcaat
    28021 gcctgatata aagcgatcct tgcttcttgt tcccaatcct cagaaacata atttcttaaa
    28081 taataggtgt ttttcaaacg tagtaaaagt ggaaaatatt tttgatacag ggcagcaaat
    28141 gcttcttcgt caccattacg tgcagcgcgc aataactcct cagacataaa ataattcctc
    28201 cataaattcg tttatggagg aatcttatca tcaatgattc atcgaactga ttagaacgat
    28261 atgttattta ttttttctca ttaaatcgtc caatttttgg gacaattttt ttaactgctc
    28321 ttcattccat ggagaattac gtcggaaatc aataaaatgc atatctttat tttcttgggc
    28381 tattgttttt tccgtttttt ttatcgtctt atataattca taagcagaag ttcgtaatgc
    28441 tccttgggaa aagatcatcc actgttctgc taaatcgctt gtcgccactg tcacttgtgt
    28501 caaacggtca ttcagctgac cagcgattct ctcgatataa ctgtcagccg tttcgtcttc
    28561 tttcgtaaaa acaacatcca actggtattt cttataattt tgttggatgc ccggaactag
    28621 ttgggcatcg aagacaacga tgacttccat tccttcatat ttcgcataat ttgataaacg
    28681 atgtaaaaga gcttctcttg catccgccat tttgtcctgc tttttaagct ggacaagttc
    28741 cggccacgaa ccaatcatgt tgtagccgtc tacaatcaac agctgttttt tcatggtcta
    28801 ctccccctga cgttgggaaa aagcctgata cataagcaaa ccagcagcaa cactggcatt
    28861 taagctctgg acgtgcccgg tcatcgggat cgtcagcaat tcatccattt cttttttcaa
    28921 tcctggactc attcctttgc cttcattacc aatgactaaa gcaattgatc ctttggcatt
    28981 ccatttttgg aagtttgtgc cggtcatatc tgtgccaaat acccaaaatc ctgtttcttt
    29041 gagctgttgc acagcttgta ccaaattcgt cacgcgtgca acagggacat gttcgactgc
    29101 cccagtggaa gtctttgtta cgataggtgt gattccaact gctcggtgtt ttggtatgat
    29161 cacaccatcg acgccacttg cgtctgctgt ccgtaaaatc gacccaaaat tgtgtggatc
    29221 ttcgatgcta tccaaaatca aaaagaaggg gtcttctttt ttctcttttg ttcgttcaat
    29281 cagttggtca agggataaat attcataagg tgtaatcgca agaacgactc cttgatgcac
    29341 gccgtgatcg ctcaaagttt ctaatttttg tttaggaacc catttgactg gcacagcttg
    29401 ttcacgtgcg atttctttca gttcttctac tttttctcct cgtgaatctt cttgaagaaa
    29461 gagtttattc cctcgccctt gttgtagcgc ttctactgcg gcatggtgcc caaagacgaa
    29521 attatcttct aatgcttctt cattttgatc agaaactgac tgatttcgtc cagtttgctt
    29581 tttatttgaa tatctatttt gttttttgtc ttcaaatcca cgtttcgatt gatgtttgtt
    29641 tgttctttct ttacccattt ttttcaccaa ctttctgaat acaccagcgg atcaattctt
    29701 ccatccgctc ggtttgtttt gtcaaatgca gatagcccat gagcgcttcg aaccctgttg
    29761 cgacccgata cgtcgtaaca tcagcatttt ttgcgctcgt atggctttta gcatttcttc
    29821 ctctgcgata ataaagttct tcttcttctg tcaaaagatg ttcttccagc atttgctgaa
    29881 tcaaaaaggc ttgtgcattc gcagaaacat aattcgttgc cgcacgatgc agcttattgg
    29941 gttttgtttc tccttgatca atcaggtggt cacgaacata gatttcgtaa atcgcatctc
    30001 caacataagc caaggctaaa ccgttcaatt gtgtgtaatc tctcatgctt ctcttctcca
    30061 tcgggttcct tgcggtgtat cttctaataa gatccctttt tctttcaaca aatcacgaat
    30121 ttcgtcgctt cggacaaaat cacgattgct tcttgcttga tttcgttctt cgatcaattg
    30181 ttcaatctct tcatctaata actcttctgc tgtaaataaa ataccgaaga tcgaaagcca
    30241 ttgcgagaat aaagcttctc cttgtgccaa gacagcggca gaaactttcg gctggtctag
    30301 ataagtgttc agccacttag caagctcata gaccactgtg atcccatttg ctgcattaaa
    30361 atcatcgtcc atttcttcga tgaatcgctg ttctaaattt tctaacaaag cgattttatc
    30421 cgcatcatct gccaaattct ctgaggcagt ttcttggcgg aatttcaaat tgtcaaacgt
    30481 attcttcagt cgttgtaaat tggtggctgc ttctttcatc gtcgtttcac tgtagcggat
    30541 cggacgacgg tattgtgtgg tcgccatgaa gaaacgcaag acttgtggat caacgttttt
    30601 gatcatttca tgtacagtga tgaaattccc tagagattta ctcatttttt catcgtcttc
    30661 gccaatcgtt acatagccat tgtgcatcca gtaattagcg aattttttcc ctgttttcgc
    30721 ttcactttgt gcgatttcat tttcatgatg aggaaattct aaatcttgcc cgccaccatg
    30781 gatatcgatc gtttctccta aatgttttgt tgccataacg gaacattcaa tatgccaacc
    30841 gggacgtcct ttgccccatg gtgaatccca agaaatctcg ccaggttttg cttgtttcca
    30901 taaagcgaaa tctaatgggt cttctttttg ctgctgttct tcccctgtac gctgacttgc
    30961 tccgacttcc agttcatcga tggattggtc acttaatttc ccataatttt caaatttacg
    31021 ggtacggtaa tacacatcac ctgaagattc ataagcatag cctttttcaa ccaacacttg
    31081 aataaatgct aaaatatctg gcatatgatc catgactctt ggatgcagtg tagcaggctc
    31141 gacattcaac gctttcgtat cttcttcaaa tgctcggatg aaacgatcag caacttctgg
    31201 tgctgtaata cctaattcgt ttgctgtacg gatgatttta tcgtctacat ccgtgaaatt
    31261 cgatacgaaa tcgactttat agcctcgata ttcaaaatag cgtcgaattg tatcgaaagc
    31321 aatggtgcta cgagcatttc cgatatggat ataattatac acagtcggtc cgcagacata
    31381 cataccgaca tgtccctttt gtatagggat gaattcttct ttttttctgg tcaatgtatt
    31441 gtagattttt atcattctga tctcctcact ttttctcctt tgattcgaac gacttttgct
    31501 ggtactccta ccgctgtagc gtcgtctgga acatctttca acacaacggc acctgcaccg
    31561 attttggcgt tttttccgat cgttaccggt cctaatatct gcgcattcgc aaagagcatg
    31621 gctccttgtt taacagttgg gtgtctttta cccgtttctt ttcctgtgcc gcctaatgtt
    31681 acgccatgga ataaaatcac atcgtcctcg atttctgcgg tttcgccaat gacgattccc
    31741 attccatggt cgatgaacac gccagttcca atcgttgctc ctggatggat ctcaacacca
    31801 gttaggaaac gccagaattg agcattgatc ttcgccaata aaaagagccg gtgctgatat
    31861 aaaaaatgag agaaacgatg ccaaaacaag gcatgaaaac cagggtatgt caaaacgatc
    31921 tcagctgtcg aacgtgcagc cggatcgttt ctctttgctg catcaatcgc tcgggtaaac
    31981 caactcatga ctttccactc ctttcgtaag aattttatgt aggaaatcat cttcttataa
    32041 agaaaagaag cgccttttaa ataagtttcc ttatcaaaag acgctttccg cgtggttcca
    32101 cttttcttca taatcaatga ttatctctga cagctaacgc ctgttatacg ttcttggcta
    32161 ctttgtttcc tataaaacag tttttcctgt tttctgtgtt tcgccaagac cactcccaga
    32221 ggcatttcgg caaccattca ttgatacctt gcaccacccg gtatctctct tgtaatgatc
    32281 agctgcttac ttttttctgt tcatcgtgtt tagttcagta cttgatttaa atgtgctaat
    32341 gatttttcac gaccaagcaa ttcgatcgtt tcaggcaatt ctggaccatg catttgtcct
    32401 gatacagcta cacggattgg catgaaaaga ttttttcctt ttacgccagt ttctttttga
    32461 acagctttga tggcagcttt gacagttgga gcatctacta cttccatttg ttctagctgt
    32521 gctttgaatg cgtggagaac agtaggaact gtttcaccag caagtacttc ttttgctgct
    32581 tcattcaata caggatgttc attgaaaaat agcgtagaca gatcaacgat ttctgcagca
    32641 tagctcattt gaggttgata caggctaacg atcttcttca cccattcgat tgtcttttca
    32701 tctgggtttt ctgctacacg tccatcagcg attagataag gcagacacat gtcagtaaat
    32761 gcatctagat ccattgcttt gatgtaatgg ttgtttaccc attgcagttt tttcgcatcg
    32821 aaagctgcgg gtgatttact taggcgtttt ggatcgaaca ttttgatcaa ttcttggtgt
    32881 tcgaagattt cgtcttcgcc cacaggtgac cagcccaata atgcaataaa gttgaacatt
    32941 gcatctggta gatagcctaa ttcgcgatat tgttcgataa attgcaagat tgattcgtca
    33001 cgtttgctta gttttttacc tgtttcactg ttgatgatca atgtcatatg tccgaaggtt
    33061 ggtggtgtcc agccaaatgc ttcatagatc atcagttgtt ttggtgtatt ggcaatatgg
    33121 tcatctccac gtaaaacgtg agtgattttc atcaaatgat catcgaccgc aacagcaaaa
    33181 ttataagttg gcataccatc gcgtttttgt atgacaaagt cgccaccgat attatcggat
    33241 tcgaacgaaa tagcgccttt caccatatct gtaaatgcgt attctgtatt gcgaggcaca
    33301 cggaaacgta caacagattc tagaccttgt gcttcttttt ctgcttgttc ttcaggtgtc
    33361 aagttcgcac atgttcctgc gtaatgaggc atttctcctc ttgcgcgttg tgcttcccgt
    33421 tctgcttcta attcttcttc tgtgcaatag catttgtatg ctcgattgct agcaagcagc
    33481 tgatcaatca gcggttgata gatttcttta cgttcagatt gacggtaagg gccgtattct
    33541 ccaggatttt caggagattc atcccaattc attcccaacc aagcaaggtt ttccaactgg
    33601 cttttttcgc catcttcgat attacgtttt tggtcagtat cctcaatacg aataataaag
    33661 tctccatcat tgtggcgggc aaacaaataa ttgaataatg cagttcttgc atttccaata
    33721 tgcaggtgcc cagttggact tggtgcatag cgtacgcgta ctttcgtcat tttcttcctc
    33781 ttctttcaaa ctagactttg actaacagca aaaattccgt cagttacggc ttctcaaata
    33841 tcatttattt aaagccactc agcacaaatt ttaccttttc taaggtaaat agtaaagcca
    33901 actggttgaa tttccttacc agttggctga atttcttttt tattttgatt gtttagtctt
    33961 tttctctgtc tcttttttat tgtcgattcc tcgtcctgca tgtgcaggtt tagcaaagat
    34021 catgcgtcca gcagctgttt gaagggcact tgttacaacg acttcgatac gttcattcat
    34081 gtaatgctgt ccatcttcta cgacaaccat cgtgccgtca tcaaggtagg ctactccttg
    34141 ttggcgttct gtcccggctt ttactactag aacattcatc gtttcaccag ggatgacgac
    34201 tggttttacg gcatttgcca acgcattgat attaagaaca ggtacatttt ggaattcaga
    34261 gactttattc aagttatagt cattggttac aatgacacca tctaaaagct tagccaattt
    34321 gatcaatttg ctgtctactt cactgatatc ttcaaagtct ccatcgtaca tttcgacaga
    34381 tataccctct tctttttgca aggcatttag gatatctaat ccgcgacgac cacgcacacg
    34441 tttcaaacta tcccctgagt ccgcgatgta ttgtagttcg taaagaacaa aattagggat
    34501 catcaaggtt ccttctaaga atccagtctt tgtaatatca taaatccgac cgtcaatgat
    34561 cacgcttgta tccaagattt tatatttatg gaaattttct cctgattttc gttctaacag
    34621 ttgactctca acttgactag ctgtttcttg ctcgattttt ttgcttcgtg aaccaaaaac
    34681 tttcttccat tcttcgattc gtgtcgttcc cattctcaat cccagatagc ctaagatgat
    34741 catcagtaaa atcggcaata cactattgac gaatggaatt tccatattgt aaagaggggt
    34801 cgagatcaca acacctaaag tcaatccgat gatcgcaccg atcgcaccga agagaagata
    34861 agtcaagctg acctcactta gtttttgttc tacttgtttg ataatagctg agatatgttt
    34921 ggccaacagc aaagataata aaaagaaaat aagtgcgcct aacaggctgt tggtaaatgt
    34981 attattcagc catccgtttg actgttgacc gattgcctgc caagctgagg gtaaaaatga
    35041 aatacccaag cttgcgccga caatgatcat cagcaaagta atgacacgtt tttgcatcgt
    35101 ttttcctccg tttcgacaat catttattag ttagcggaac acacgcttca acgtttcagc
    35161 caaagttgct actccaacta tctcgattcc ttttggcgct tcccagttac ctaagttgtt
    35221 tttaggtagg tatacttttg tgaagccgag tttttggact tctttgactc gttgttcaat
    35281 atgactgaca cgtctgattt ctccagtcag tccaatttca ccgatgaaac attccgttgg
    35341 ctgtgttcct ttttctttat agcttgaagc aatactgaca gcgatagcta aatcaatcgc
    35401 tggttcattt aattttaccc cacctgcagc ttttaagtaa gcatcttgat tctgaagaag
    35461 caacccagct cttttttcca gcactgccat gatcagagat acccgattga aatcaagacc
    35521 tgttgttgtt cgtttggcat ttccgaacat agtaggtgtg actaatgctt ggatctctac
    35581 caaaattgga cgtgtccctt ccattgccac aacgatagca gagccagttg caccgtctag
    35641 gcgttcttct aagaaaatct gtgaaggatt agcgacttct tccaatccat gctcatgcat
    35701 ttcaaaaatc ccaatctcat tcgttgagcc aaatcggttt tttactgctc gcaaaatccg
    35761 aaaactatga tgttgttcac cttcaaaata taacaccgta tccaccatat gttctaacat
    35821 tcttgggccg gcgatcgagc cttctttggt aacatgaccg acgataaaaa tggctatccc
    35881 atttgtttta gcgattttga gtagttctgc agtggtttct cttacttggc tgacacttcc
    35941 tgccacactt gtgatgtctg gctgcgtcat cgtttggatg gaatcaatga taacataatc
    36001 aggggagata tgttcgatgg cacgactgat ttcgttcata tctgtttcag cgtatagata
    36061 aaattctgtg ttgatacttc cgaggcgttc cgcgcgtaat tttatctgct ctgcgctttc
    36121 ttcgccggat acatataaga cttttccgcc tatggctgct aattgctgag aaacttgtaa
    36181 cagcaaagtg gatttcccga tacctggatc gccaccaatc aagaccatag accctggcac
    36241 cacacctccg cctaacacac ggttcagttc ttctaatttt gttttgatcc gaggttcttt
    36301 tttagggacg acgtctgcga tttttgttgg ttttgctttt tctcctgtca aacttgtccg
    36361 agttctgcgg tccgttgtat cttgttcgat ttcttcgacc atcgtattcc attttccgca
    36421 atttgggcag cgtcccaaga acttaggcga cacatacccg caattttggc aaacaaattg
    36481 tacttttgat ttttttgcca ttgtaccgcc tccttttatc ctaatcatga gacattaaat
    36541 caagcttaag tatctttaac gttttattta ctggaagaac caaatccgcc ttgacgttga
    36601 gcagtcgttt gatcttgatc tgcttttaaa aacggcaaaa agatcccttg gccgatacgc
    36661 tcgccttttt tgatcactac atccttgaaa ccaaagttgg tgaattggaa catgatatgg
    36721 ccttcatttg cctcattatt gtaataatca ctgtcaatca cacctactcc gtttgtcaac
    36781 actaaaaacc gcttcaacgg attgcttgaa cggttagcaa gctgcaaaaa ttcatcttct
    36841 cccatgtaag ctttgattcc agtaggcacg agggttggtt tcaattgttt ttcattttct
    36901 gatacatctt ttttcaatcc atctgcgact gtttccaacc cctttttcca gcctgctttc
    36961 cagatacttg gaatcacgac ctcttctgct gcttcaaaat catagccagc agcatgatgt
    37021 gtagcgcgct gcggtagatt gatattttga tctttatatt tagaaataac ttcaaatcct
    37081 ctttttctca ccggttttcc tccctaaata aactactcct attctaacat atccgaggct
    37141 gtaaaagact ttctttacaa attcttcaag aaattctgct atcttaaagt aaaccattaa
    37201 ttcgttcttt ttccaaacga ctgcaagttg tacaaaaaaa ctatttttta catgacttta
    37261 ctcgtcaaaa caagtagaat agaacgaaat taatgagtgg atatttgatt gaggtgtcac
    37321 atgcgtaaag aaattaaaaa tgcaaaacga attattgtca aagtaggaac aagtacattg
    37381 atttatccca atggaaatat caatcttgcg gcaatcgatc agttagcttt tgtcctttct
    37441 gatcttagaa atcggggaaa ggaagtgatc ttagtctcat caggagctgt aggcgttggt
    37501 atgcataaat tacatttgtc agaacgtccg actttgattc ctgaacagca agctgcggcg
    37561 gctgttggtc aagccgaact gatgaatatc tataatcaaa gattcagtgt atataatcaa
    37621 cagacggcac agatcctcgt gacaagagac gtggtagatt atcctgaaag tcgtaaaaat
    37681 gtgaggaata cattggaaca gcttttgatt atggacacga tccctatcgt gaacgaaaac
    37741 gatactgtag cagtggatga attagatcat ctgacaaaat ttggcgataa tgatcagctg
    37801 tcagccatca tggcaaaact tgtcgcggca gaccttttga tcgtcctttc tgatatcgac
    37861 gggttttatt cagataatcc gactacaaat cccgaggctc agatgtatcg ctatatcgat
    37921 aaaatcgatg aaaagattct ggcacaagca ggtggtgctg gtagcacatt tggaacaggc
    37981 ggtatgcaga gtaaattaaa agccgcttct aggatatttg aagcaaacag cgcaatgatt
    38041 ttagcaaatg gaaaaaatcc ggcaattatt tttgatattc ttgcaggaaa agaagtaggt
    38101 actttattta aggaggactt gaaatgactg acttgatgca attaggacaa caggcaaaag
    38161 atagcgcgca acaactagca cttatgccta caaaccgcaa aaatgagcta cttgttcaaa
    38221 tggcacaaac catcaaaaag aatcaacaag cgatcattga agcaaatcat aaagacttag
    38281 aaaaagcagt cgaaaacaat atcagtgaaa cgatgcaaga ccgcttgcag ctgacacctg
    38341 agcgaatcaa tgccatggct acagagatcg aaaaaattgc ttcgttagac gatcctattg
    38401 gaaaagtaga tgagatgtgg acgaacaccg acggattgag aatcggcaaa aagcgcgtgc
    38461 cactaggcgt gaccggcatc atttacgaat ctcgtccaaa tgtcacgaca gatgcagcta
    38521 gtctagcatt caaatcaggg aatgccgtta tccttcgcgg tggcaaagaa gcattcttct
    38581 cgaatcaatt attagtccaa ttattgcagc aagtactggt cagtgctggc gaatctcctt
    38641 atgccatcca gtttgtcgat gatacttctc atgaaactgc aggacagttg atgcgattga
    38701 cagaatactt agatgtgctg attcctcgag gcggagcaaa attaatccaa cgagtcaaag
    38761 aacaggcaac ggtacctatc attgaaacag gtacaggaaa taatcacgta tatatcgata
    38821 aagaagcaca gttatctatg gcagtgaaca tcatcgtcaa tgcaaaagct tcccgtccat
    38881 ctgtctgtaa cgcggcagaa acattgctga tccattctga gatcgcacct tttttcttgc
    38941 cagctattga aaaagaactg gtagaacacg gggtctcttt acgtgcggat gctcgtgcgt
    39001 tagaatatct agagacggct gctttagcag aagacacaga ttgggatact gaatatctag
    39061 attatatcct tgctgtcaaa gtggtcgatt ctttggatga agcaattgca catatcaatc
    39121 ggcataatac taaacattca gaaacgatcg tgacagatag ttatgcggct agtcaacgtt
    39181 tcttaaatga agtggacgcg gcggctgtct atgtcaatgc ctccactcgt tttacagacg
    39241 gatcggtatt tggttttggt gcagagattg gtatctctac tcaaaagttg catgcccgtg
    39301 gtccaatggg gttaaatgaa ttaacttcca caaaatatat catttatggc gatggacaaa
    39361 tccgcgaata atgtttcgtg tgaaacatta ttcccgcctt ttgccttttt tctgtaaagg
    39421 ttctatccaa ctagaaaggt gtcaatatgt ttgaaatttt aatgattttt tttatttacc
    39481 ttatttctct gaatatcgct gcttttctgg gagtcggtat tttatccctt ttctttcaat
    39541 tcaaaaaacg aagcataggg agtcaacggg aaaaatggtc gcagtatttt gacaaaatcg
    39601 ggcaaaaagg gctggttaca cgcttgcaca ttagttacat ggttgcatta tgcttattag
    39661 cgacaatcaa ttactattct tttttcgatc attcaatcgc ttatacgatt acgctactga
    39721 ttgctgggat ttttcactta tcttataaat atcagctgaa taaaaaccac ttgaatcgga
    39781 ctttccgcta aaaaatatcc gtacgataag tagagtgcct tgaagatcgg caaaaaactg
    39841 ccggactttt tagaggctgt gacaaagatt ttgtcacagc ctctttttcc atataaacgg
    39901 cgttcgccta ccagctgcct ggtaaatctg tttcctcttc gttaagaagc gaaaatccgt
    39961 caaatgtttc gccatcataa taacgaagca gctcatccat ggacaagttc atcgtttttt
    40021 ctttttcttc ttccgctgat tcagccagta gctgttcccg atacacctga tacataccag
    40081 ctattttttg ctgcatcgct tttctagttt caccttccgc attgattatt ggcaattctt
    40141 tgatatagcc acgataaatc aaccgatcat ctgaaaattc aatgggtaat tcaacgagtg
    40201 tcaacccgac ttcctgaaaa tattcttcca gcatctatta tccccccatt ctttttctta
    40261 aatgaatttt agcttaccta ctgaaaattt tccagtttca ttattttgag aaaaaaaggg
    40321 aatgtgacaa aaatcgtgtc acatcccctt tttccgaata aatggtgttc ttctgccaac
    40381 tcctcaatca taagtcacaa tattcaacaa acatgagaaa ctgttttttg aaattgttcc
    40441 ttgtgattca gagttaaacg acagtctcac aacctcttgg taaacggcgt tcaaaagctt
    40501 gcatctgcgg taataagccc aaccaaacga aaaatatgag aagctatttt tgtttggctg
    40561 ttcttatgac ttgatgcagg acagcttttt cacaacctct gatttcttat tcttcttcat
    40621 ttgtagcaaa ataattacgg tgataaatga tacaacatac actgataaga acaatggcac
    40681 ctgcaaaata aaacgcatag ctttcaccaa tatgttcacc aatcacacct gcaataaatg
    40741 gtgctaaagc tccaccgaaa aagcggacaa aactatagct ggacgaagca acgtttcgtt
    40801 gcagacctgg tatttccata gcaatcgtcg tcaacagtgt attgataatt ccttggaaaa
    40861 atcctgctaa cacaatgctg atcggtacaa ggactggcat agaagttcca gctcctaata
    40921 acagcaaaca aataatgaat aagacaaatg ctgctaaaat tgtccgataa gtcgtaaact
    40981 tccgctcaag agccggtgca acgaaaatcg aagcaatagc cagaagcaca ccccagccaa
    41041 aaaatacaaa accgacttct aattcagaat agccaatcaa taaaaatggc gcatacgcaa
    41101 gtaaagtaaa gaatccgaaa ttatataaca atgcgattag tccaactgaa cgaagtttat
    41161 gattgcttaa cgctttgaca ccttcccaaa ggcctacttt tctctttggt ttctcagttt
    41221 caggtaaaag taccgctagg gctataaaac cgcaaaacat caaaaatgct accccaaaaa
    41281 atggataacg ccatgaacca ctgcccaaga ccccaccgac tagagggcca acagccattc
    41341 cgcagccaag tgctgcttca tacatcatga ttgctttttc tgtgttacca actaaaatac
    41401 tgacgatcgt tgctaaagca gtagagacaa ataaagcatt cccgacaccc cagccggcac
    41461 gtaacccaat cagcattccg atattcccag ataatccgcc aagaccagcg aatacaacga
    41521 tgataaacaa tcctgtcatc aatgtttttt caaaccgatc cgactagata agaaacctgt
    41581 aaatagcatc accacaccag tgactaacat gtaactagta aataacaggg tcgtttcagc
    41641 tggcgtagcg tttaactgtg cagcaatcgt ttttaagatt gggtctacta gacccactcc
    41701 cataaaagcg atcatacagg tagctgctac aactagcgct gaacttttcc cctttgtttc
    41761 ttcatttgtt tgttcttgta tatctatttg attctccaat atttccatcc ctttctctct
    41821 attagcatca tacatgattt attttacatg taaatatgca catgtaaaac gtggaaactt
    41881 tactgtgata taataaagaa aataagacga gaggtaggat ttttatgaat actttagcct
    41941 atatattatt atgcgtgctt ttatccaaac cacgttctgg gtatgaattg aagcagctga
    42001 tcacaatttt ttgggaagcc catcacagtc agatctatac aacgcttgcc aagttagacc
    42061 agcagggtta tgtgaccgtt ttggacaaag acgagcactc tcaaaaaaag atctaccact
    42121 tgactgatga aggacgtgct cttgtagagg aatggatcaa agaggaaact cccgctccta
    42181 cgcaaaaaga tgaatttcta gcaaaaatct atgctttttc gacgctcgat aaaacaacag
    42241 ctactggact gctattcact agagaacaac agctgaacaa aatcatgcaa aaaaatcaaa
    42301 aaaaattgaa tgacctctcg ctagacaaga aacaagaatt tggacgttat gttgtgatcc
    42361 agcgcagaat tatgctttgt cagcaggaac tccaatggtg tcagcaagta agagaacaaa
    42421 tgcagcagtt ttttgagtaa gggataaaca gaacctttct agaaatatct attgaagagc
    42481 aaattatctt caataaaaga gcaatacagt tggaaaagaa aaagcgatcc gaacgacagg
    42541 ccaaaaccta tcgttcggat cactattttt ctagaactgc attcaagaga ctatgacaaa
    42601 aagcatgcca aggccttttt tcaaataaca gtgttccatc attcattact ttgaattgct
    42661 tttagcacac ttcttgaaag cgggccaacg atgatcaact gcaacggtaa agcggcaatc
    42721 acattcattt tccaagcatt catataagca gagaataatt gatcaggtat tccttgttcc
    42781 atgatcacac cgaataaaga catacatgtc accattccta aaaccatcaa gcatgaaata
    42841 gttaagatca tttggacctt gctttctgga tttactggta gtttaaaggc aatttttttc
    42901 gccagcacac cgatgatgaa gacatccaaa atgaaagcca ccacgaatcc aggcactaga
    42961 ccaatcaaca aacttgataa atgaagatct tgatgcagcc ataaattata cgcgctcatc
    43021 cccaagacca tcaaaaaaca catcattgtt gtaaaaatta ttccttcttt tttatttgta
    43081 ggcaatctgt accactcctt taaatttgtc acgaaaatca tcgtagcaca tttaaaaatt
    43141 tctcgtaagt acttttttta ttttctgccc ttttatttca taaacttcat cagccgtacg
    43201 ctcgacaaag taagaatcat gagaagtaaa caaaatcgtt cccggatata tttgcattag
    43261 cttctctaaa gcttcgatcg ttgccatatc aataaaatta gtcggttcat ctaacagcaa
    43321 cacattactt ggcttagtaa aaagcaaagc aatcgtcaga cgggtcgctt ctcccccact
    43381 taatgtacat aacggtttcg tcaaagtttc ctgagcaaac cctaagtgat tcagcaaact
    43441 acggacaagc gattctgaaa actctgtttg tctcatgaca aaacgaatga tggattcttc
    43501 agatgtcatt tgataaccct tttgctgata tacttgaaag cttactttcg gagagagaag
    43561 gattccttct ccttgtttgc ggatatgttc taataaggtt gtcttacctg aaccattttc
    43621 accgacaatc gcgatttttt tacctaaaga aaactgaaaa tcaccattta ccagtaatgt
    43681 tctcccactt ctttccaatt ggacattttg tcccatgatg ggatagcggc tgtggagttc
    43741 aagagatttt ggtactggaa aacggatttg tttcatctgc tgcggcttgg ttgtttctcc
    43801 tattttttgg agtcttctct ctaatgtttt cgcattcttt tggatggctt tttgtacact
    43861 gtctttttgt ttagaggaag acaaccgatc cggtctgatt tgttgctttt tctttttact
    43921 ggacactttt tccaactttt ccgcttgttt tttcttttct tggatcgatt tttccaatcg
    43981 ttttttctct ttcatgatcg actctgcttc tcgtagctga gtctttttct ccaattcctt
    44041 ttgagtgaga taggcactat aattccccga aaactctcgg atttctccgt cttttacttc
    44101 ccagattttc gatgctagct catctagaaa atagcgatca tgactaacaa aaaccagcgt
    44161 accataataa taacgaagct cttcaatcag tcgatcaata ctttttctat ctagatgggt
    44221 tgttggctcg tctagaagca tcccttgttc ataagaagaa agaagacgta tcaactcgat
    44281 ctttcgttct tcccctccgc tccatttccg ctctgaagtt tcttccagtc ttaactggaa
    44341 atgactggct aattccaaat ttaggtcctt tgcttcagcg agataggtta attgaggcag
    44401 gtagttgaag gtgatctctg tttggatttt cccatgatcg ggaaaaagtt caccggctat
    44461 tagtttgagc aaagtcgatt taccgacacc attttctcct atgatcccta tacgatcttg
    44521 ctgatagaca cgaagagaat caatagatag ttctagctgg ttgccaaagc tgacttgtag
    44581 atttgttata tttactgcta aattttccat atgttttaca ctcctatttc atgtaaaaca
    44641 acaattatcg atactaaaaa agagcagaaa aatctgtttg caaaaaaact gcatcacatc
    44701 ttttcctact ctgaacgaaa taactatgac taaatcacca aatctgtcat agctttcacc
    44761 tattctactg tcgttcgaaa aaatggacat actccatcca tgaaattgtt gtttatacat
    44821 gtcttttgaa tttatttagt tgttattcaa aagttcgaaa cgtaatttca tcgatgcagt
    44881 catttttccg acctcctttt ttattaggtt accacacacg attcaaaaaa agcaatagct
    44941 actgaatagt aactgaaaac cttttattcg aacgtagtga tcttttctgg tgctaaacga
    45001 acagactcgt aaccttcttc taccgctttt cctattgata aaataataac tggaacataa
    45061 cggtctttat ccaaaccaaa tgcctctgcc aactgatctg cttcgaatcc accaattgga
    45121 tttgtttcat agccatgatc acgcgcaact aacatgaatt gcatagccgc taagctagaa
    45181 tcgactttga ctacatcgtt catttcttct cttgaaaaac tcttgtaata aggaatgatc
    45241 gcagctaatt gttgatctct gacttctttt ggcatcttcc ctgattcgta agcttggtta
    45301 tagatttctt cgccatattc gtaacattgc atatcgccaa aaatcatgac cattgcagaa
    45361 gaagtatcat tttgtctcgt attgaaacgg atcaaaggac gcaagatttc ttttgcttcc
    45421 tcgctttcag cgaccacaaa gcgccatggt tgcatattga cagaagaagg tgcagtcgtc
    45481 gcttctttga tcatttccag catttcttcg tgtgggattt tgtatgtttc atcatatacg
    45541 cgaacggatc ttctaccagt cataattgtt gaaaaatcat ttttttgttc cattattatt
    45601 aacctctttc gtttctgttg ttatattgca aagttgggta ttcaatttat ctaaaagtgt
    45661 tagaaattgt ttcatttcta catcgctgaa agccggggat agcacggaac ctgtatcttt
    45721 atggtccatt tcacaatgct cgattttctt ctgggctttt tctgttagcg ctacatacac
    45781 ttcccggttg ttctgaggat ttctctgacg cgaaacatag ccatttgctt ccaatacctt
    45841 cagatgacga gtaactgctc cttgatcaat ctgcaacttt tcttgcaaac tgctttgtag
    45901 caatggattt tcttctttca gtctcatcat gatctcgtat ctagtaagac ttataccgat
    45961 attttcttca aagatctgga cgattttttg atcggctaat ttgatttgat ataaaaggtg
    46021 actaatctct tctaaagaca taatttcctc ctttctaata attgactcgt caacgattga
    46081 cttgtcaata atagaataaa aaaagaaaaa agtcaaagaa tcagctgtgt aataaaaaaa
    46141 acgctctcaa tagaaaagta tagagaaaag aaattttttg tagaatgaac ggaaaaaatg
    46201 ataaagaaag cacaacgcta aaaccaagat tattgattct tatcaaacta tagaagatag
    46261 ctcttctgca gtagaaaatt ttacaccgcc aaaaatttcc gaaatcgcct tttgcaagaa
    46321 tcccgtcgaa tattagaaat tggatcagta tgcttaaaca gtaataaaaa agttatgaca
    46381 agatgttgtc acaacctttt ttgagtaaac ggtgttcaaa aacttgcatc tgcggtaata
    46441 agttcaacca aacaaaaaac atgaaaatct gtttttgttt ggctgttctt actacttgat
    46501 gcagggcagc tttttcacta cctcttttta ataaccataa aatcctattc cttcatatct
    46561 ccagcccatc ggtgttagcc aatctctttc cttagcactc aaggtatagt gatgggtacc
    46621 agttttttca tttggattaa atagtcgata aattggcttg gaaccaccag aataaaaact
    46681 tagaccttca taacgccaac cgatttttgt taaagagttg atctcagatt gtgccattgt
    46741 gtaatgatgg tctccactgt aaggattgta taaacggtag acaggttgtc cgctgtttgg
    46801 tgcttgccaa gcaatccctt catattccca gcctacagtt ggcagataat ttttttctcc
    46861 ggcattcaat gtatataaat gttctcctgt atgacggtta tacagacgat acatcggaga
    46921 agttgaagtt ggtgctgtat catactgtgt cagattatag gtttcgatta cattgttcaa
    46981 tgtagaacca taattaggcg cagtggcata acgacctgtt agccaagccg tagcatcttt
    47041 gtaagagttc gtattgcttt tccatgcacc ggaatagtag taaacgcctg gctgaaaaga
    47101 agtcgtcttc aataccgtta cgttatcttg caatgattct ttgtacgaag gatattttct
    47161 aaaagcggca ttcaccgtaa tccattgccc attcacatat tccgaagtag gcatcgtaac
    47221 agattggcca ttatagcttc ctttaatccc aaatagattg taattagggg cagaagccaa
    47281 agtactgttc ccccagccac tttcaacgat ggcttgagca atcatgactg atgcatataa
    47341 gtcattggca cttgccaaac tttgtgcagt tgaggcaata ctatcaatga acgcttgttg
    47401 agaattagca gatgagcgag cataaaaagc atagccagta tagttttcga attcagacaa
    47461 atctgcttga tgggtatgtg tcaatgtttg cccatctgtc aattggttcg tgatttcttc
    47521 tgcattctct ggattgttct gagcttctgc tgatgtactg tcttcggttt gtgtttgttc
    47581 tgttgtttca gttgttggtt cttcggttga aattgtattt tctgagacag tagctgactg
    47641 caaagtactc tctgtatcgt tttcaattcc tgtttctgaa gaactcgatg tctgagttgc
    47701 gacagtttct gtcgattctt cagctagcac tgttgtgttg gcaactgcta gatttcctaa
    47761 aagaataacg ctaaataata aattctttgc tttcatcttt tttctccttt gaattatgaa
    47821 acttttccta aataacagtg taactaaaaa agtaaaagca agtcaatgtc catatttaaa
    47881 taacatttgt ttctttttga taaatttgct ttttctacat aaaaagacgt aaatgaagaa
    47941 tattcttctc cattcacgcc ttaaattgat ggtcgtttga ataactattt aacaagtaat
    48001 tctctttgga tattatccgt tatggattat acttcctgtg tcgtcggacg gataatcatg
    48061 ttactgacag acatccggtc tggcgtttct atcgcaaatg ctacagcaga agctatatct
    48121 tcggaggtca atccccattc tttttgcgct tcatgaagtt caagagcagc ctttttgtcg
    48181 ctgatggttt gatataattc agtttgaaca gctcctggag agatgatcgt agatttgatg
    48241 ttattttgcc gttgctcttg acgtaatcct tccatgattg cacggacagc aaattttgtt
    48301 ccgcaataaa cggcggaatc aggataaaca acatgtcccg ccacagaatc agttgaaatg
    48361 atatgcccag atttttgttt ttccatgatt ggaagtacgg cggaaattcc atttaacaca
    48421 cccatgatgt tgatatcaag catattttgc cattcatcac ggtgaccttc aactaatgga
    48481 gcggttggca tgattcctgc attattgtac aatacatcga ttcgaccgaa cttttccatc
    48541 gctaaatcga taactgcttg gacttgtgca aaatctctta catctgctgt ttgaatatat
    48601 agctcagctt ctggtaaaga ttcttttatt gcttttaggc gatcttctcg gcgtgcagct
    48661 ataactagtt tagccccttt ttctgctaat agcttcgttg ttgcttcacc gattccgctt
    48721 gaagcgccca tgatgacaat cactttttct gataaatcat tcattctatt ctcctcctgt
    48781 tttgaaaaat ctcttgctta tactcactat ctcttatttc atcttactgt tcaaataatc
    48841 cgttcgacag gtttgacgat tttggcaggg attcctgcaa cgatggtatt gtctgggaca
    48901 tctttcgtaa cagttgcatt cgctgcaaca atggcattct cgccaatcgt tacgcctggc
    48961 agaatagttg ctcctgctcc gatccaagca tttttcttga tgtggattgg ctttactgac
    49021 aagcctcttc gttcttttgg atcggttaga tggttcaccg tgatgaggtt gacacgagga
    49081 ccaatcaata ctgaatcttc taaacagatg ccacctaagt caacgaacat cacttgacga
    49141 ttgataaaga catttttccc tatactaata tgtttgccga aatctgtata aaaaggcagc
    49201 agaacagtca ccgtatcatc tactttgtca ctaatgatat tttctagccg tttgcggata
    49261 tctgctggtt catggtaccc agtattcagc gctgctaaag gctcttcgtt ttcagcttgg
    49321 atctgatgga tcacttcaaa gagcggatcc gttactcgaa tctctttatt gacgatttgt
    49381 ttttcgatga ggcttgtcat tttgctccct ccttttatcc ttactttata acggacggct
    49441 tatcatgtct aatacttata aaacatactt aactattcct tttaactata cttagtggta
    49501 tgctttttta aaaacaggag ggaaaaaatg gatattcgta tactgacgta ttttttagca
    49561 gtagctagag aaaaaaatat cagccgagca gcaaaatctc tgcatatcac gcaacctact
    49621 ctctcaaaac aactgaaaga tttagaagaa gaacttggtg tgacactttt cactcggggc
    49681 tcccgagaga tacagttgac ggattctggt cgatatcttt attcaaaagg aaaagaaatc
    49741 ttgtcgttgg tagaaaaaac ggcgaacaat ttaacaaatg acgcaatcat ctctggagaa
    49801 atctacattg gcggaggcga aactaaagca atctctttca tttctgatag ccttcattcg
    49861 ttgatcaagg cgcatcctga tatccagttt catttatata gcgggaatgc agatgatatc
    49921 atagacaaac tggatagcgg attacttgat tttggactcg taatcgaacc gacaaacaaa
    49981 caaaaatacc agtcatttcg actgccagcc caagatcgtt ggggactttt gatacatcga
    50041 aatcatcctt tagcaaagca aaccgtcatc catccgcagg aactgaaaac tgttcctttg
    50101 atcatttccc ggcaaacgtc agtggacagt caactagctg aatggctagg tttcagcata
    50161 gatcagttat cgatcgtcgg aacatataac ttattgtaca atgcttcttt gatggtcgat
    50221 aacgggactt ttggtgcatt agctctagat gggatcatca atacttatgg gacggaaaaa
    50281 atattcatcc cactcgatcc gccattacaa gcttcactga atctcatttg gaaaaaagac
    50341 cagcctcttt ctcctgctgc tcgtaaattt ttagatgtcc taacggagaa atacagttaa
    50401 gtagagtttt tttccttcgc tttcagcttt ttaacaacga ataagataag caaaagatcc
    50461 aacgattaaa taacataagt ttcttaattt atttcttcct tttatttctg ataattccag
    50521 taaattacta taattataaa aaaagaattg acaaaacata actgtctata taaaattgat
    50581 tacgttaaca ataattcgtt tcatgtgact agatcatact aggcatgaaa aatctctgag
    50641 gaacatggtt tccctaggag gtttttcgtg tctatttttg tttggccgca atcaactggt
    50701 ctagcaaacg tgaaaaccaa atcttcaaaa agggtgcgcg catgaaaatc aaaaagatct
    50761 ttaatcaaaa tgcagtattg gtagatgacg gtggacagga aaaagtagct attggaaaag
    50821 ggattggatt tgacagaaaa agaaatgatt tgatttttga tcgtgatgtc gaacggatat
    50881 ttgtcatgga accagaaggt caaatcaagt tgcaaaattt acttaatcag attgatgaac
    50941 gctttttatt tgcagcagaa acgatcattg atcatgcgga aactgttttg atggaaaagt
    51001 tgaatgaaca tgtattgatc gctttgaccg accacattgc tttttctgcg gagaacatta
    51061 ataacggtat cgtcatccgc aacaaacttt taagagaaat cgaagtgctt tacagtgatg
    51121 aattcagtat tgctcaatgg gcagtagagt atctgacaaa agagcttggg attccatata
    51181 cttatgacga agcaggatat atcgcaatcc atattcacag cggacgaagc ggtcggaaca
    51241 ataaccatcg cagtatccgt gaagtgacga ttgtatctga catcatccat ttagtggaat
    51301 cagaattgga aacagatatc cattcagaac cattttcact gaattattca agactggtga
    51361 atcatttacg actgcttcta caacgaaccc atgcgcaaca atatgctgtt ttagacacgg
    51421 aaatcgtaga aatggtcaaa cgaaaatacc cagaaagcta taagatttct aaaaaaatcc
    51481 gtgtgttgct gaccaaagaa taccagctcg cgatcacgaa agaagaactg ggttacttgg
    51541 ccatccatat cgagcgttta agaagcgcaa tcgtacaaac aaatgttaac aatcatgagg
    51601 aggaaaaaaa ttgaaagcat atctacaacg aatgggacgt tcccttcaac ttccagttgc
    51661 ggtcttacct gctgctgctt tactagtagg gatcggaaac tggtgggcat cttatagtaa
    51721 cgacattgtc gctcattttt tacaagctgg cggtaacgca gttttaggtc aattaccttt
    51781 gctgtttgcc gttgggttag cactagggat gtcagtggac aaatcaggtg ctgctgcctt
    51841 ggcaggtttg gtcgcatttg aagttccagt aaatgtttta aaaactgatt cagtagctac
    51901 tttattgaat atcaaaccag aatcagttga tccatctttt gctcagatca gtaacgtatt
    51961 tattggtatt attgccggat tgattgcggc agctctttat aatcgtttcc acgaagcaaa
    52021 attaccgatg gctttatctt tctttagcgg caagcgtcta gtgccaatct tggctgcctt
    52081 tgtcatgttg ctgatcagtg cagtgctact gctcgtatgg cctccggttt actctgcttt
    52141 agtttctttt gctaaattca ttttgagttt aggctggggt ggtgcaggtc tttatggctt
    52201 cttcaaccgt ttactgatcc ctacaggatt gcatcaagca atgaactccg tgttctggtt
    52261 tgacgtagca ggaatcaatg atattggtaa atttttggct tctgaaggaa caaaaggcgt
    52321 aacaggaatg tatcaagctg gatttttccc aatcatgatg ttcgggcttc cagcaggagc
    52381 atatgctatt tacagaaatg cacgtccaga aaacaaagca aaaacagctt ccttgatgct
    52441 agcagcagct tttgcttcat tctttactgg tgtgacagaa ccacttgaat tttcatttat
    52501 gttcgttgct tggccattat atgtcttgca tgcaattttc actgggattt ctttagcagt
    52561 gagtgcattc ttccattgga cagcaggatt tgcctttagt gccggatttg tcgattactt
    52621 cctatctttg aaaaatccga ttgcgaatca gccattgatg ttgatcgtcc aaggattagt
    52681 aacagcagtg atttactact ttggctttaa ctttgctatc aaaaaattcc atctgatgac
    52741 tcctggccgc gaggaagcag atctttcaga tgacgatact gcaacgacta attcagacaa
    52801 taaatatgcg gcacaagcaa gcaaaatcta cgctgcatta ggcggagccg acaatgtaac
    52861 ttcgatcgat aactgtacta cacgccttcg tttgcaagtc aaagatacag gcctgatcga
    52921 tcaaaataaa atcaaagcca ctggcgtacc tggtatgaag atcatcgacg gaaaaaatgc
    52981 gcaagtcatc gtaggtacag aagtacaatt cgttgcagat gagatggcaa aactacatgg
    53041 tggtgctgca gcacgacctg cacaaacaaa caccgtggtt aaaacagaaa catttgccgg
    53101 tgaaacgatc gaacaagata tttacgctat cgcaaatggg aaactgattc caatcactga
    53161 agtttcagat gatgtattcg cggaaaaaat gatgggtgac ggctatgctg tattaccaga
    53221 aaatggagaa atcttctctc caatcgctgg tacgatcaca aacattttcc caacgaaaca
    53281 tgctgtcgga atccaaacag atgctggtat cgaagtcttg cttcatatgg gcatcaacac
    53341 tgttgactta aaaggcgaac cattcacttt atatgtagaa gaaggtcaaa aagtcgcaag
    53401 aggtcaattg attgctttag ttgatcttgc cgctattcaa tctgcaggca aaaacacgga
    53461 tatggtcgtt gtattcacaa atggcgacaa agtccaaagc ttagaaatcg aacccgcacg
    53521 tgatgtaaaa gcaaatgata aaatcggctc tgtttccaac aaagcctgag ccatcgtctt
    53581 ccccagactt ttttatcgat aaacaaacag gagctgagac aaaaatcttg tctcagctcc
    53641 tttttccgaa taaaaacggc gttctcctgc caactccgcg gtaataagtc cagctaaacg
    53701 aaacatatga agagctattt tttatttgac tcttcttatt acttgatgca gaacagcttt
    53761 ttcacaaaat ttttcttcat actcaaaact aatcggcttt ttcacaacct ctttatacat
    53821 tattcctgat ccaatatttc ttttaatgct gcttcaagag aagttaatgg ttttcccaat
    53881 actttttcta aatcatcaga ggaaatagct aactgatcct ttttaatatc atgttggatc
    53941 gctaaaaaca tgtcagctgc ttcttgaggg aatccggctt cttttagatt ttcgacaaac
    54001 gctgcatcac ttgcttcaat aatttctaac tctttacctg tcgcacgctc taatgccttg
    54061 gctaattctt catagtcagt tagattgccg gataattcta agatttctgg agagtcactt
    54121 tctactagta cttttgctgc agcttctgca tattcacgtt tcaatgccca acctgttttt
    54181 ccatttcctg cagcataaac gaattgacca gtttttaaag cctgcccaat gataggtaat
    54241 tcattctcta cataccaatt attccgtaaa aatgtatggg aaatacctga atccttaatc
    54301 attttttcag tgaattggtg atctggcgct aatacactga tcgagtgatc ggcatctgca
    54361 aaacttgtat aagcgatata agatacccca gctgcttgtg ctgccttcac tacattctta
    54421 tgttcggctt gacgatttcc tggaacgcca gagacaaaaa gcaatcgatc tattcctttc
    54481 aacgcttctt tcattgagtc taaatcatca taatcaccaa tacgtatatt aaatccagct
    54541 tctttcagtg cttctccttt ttcttcacta cgtactagta catagatttc attttgtgga
    54601 accatctttt ttaagaattc cagcgcataa ccaccaaaac ctccagttgc tcctgttact
    54661 aaataatgca tatttgccac tccctattct ttttatttgt taagatttac agctgtacat
    54721 ttataaatta cacctttatc ataaagagtg tggtaagata agtcaagcaa aaaaaatgaa
    54781 aggatgacaa ctgatgaagt attctctgca atttagtgat gcaatccatg tacttgccta
    54841 tattgaaatg tttcaagata cccgatcact ttctagtgag atgattgcca gtagtatcga
    54901 aacaaatgca gcaaatgtac gtaaaatcat gagtcagctc aaaaaatccg gtttgatctt
    54961 tacaaaaacc ggaaaaccgc agccttccct tgccaaaagt ccagatcaga tttctttact
    55021 agatgtctat cgcagcatcg aaggtaatac acagcttatc caagtcgatc caaaaacaaa
    55081 tccaaattgc gtcgttggtg cgaatatcca agaagcttta gaagaaagct acgctcggct
    55141 gcagaaaaag gcagaagaag aaatggctaa gatcacactt gatagtctga tacataaaat
    55201 agccgttttg gaaaaagaaa aaagaccaga aaacacaggc ctcgtagaga gatttttata
    55261 attctctcta ctgtgcctgc atttttctga tcggaatcgt ctacataaat tcttttattc
    55321 tccgggggac aaaagccttg tcatgcccct ttttcctctc taatgctcag gtcaaagcgc
    55381 tgaagtcatg acgtcttgat aaacggtgtt caagtagctg accctcggca ttagttctga
    55441 aaaatgcaaa atatggaaag ctatttccca tttttcctct ctaatgctca ggtcaaagcg
    55501 ctactttcac gacctctata ttatcatggt ttattgacta ccggtatcca gatttctccc
    55561 atatatttcc cgttggtaac tcccatttcg actacagcat ttggaccccc aacataggcg
    55621 taatcttcta cttctcttaa aacatgccca aaggccgtat tcgtcaaatc atttcttaat
    55681 tcttcaggcg attctgctaa agcgcttaca acaagatacg ttccttttgg gaatgggatg
    55741 attcgcgtag tgtttggaac atcctgactc gtttgaacac cgacatagta catcattttc
    55801 ccgttatagg gttcgttgac tgtaaagaaa taatgatttt cagcagcttg tttcaatgca
    55861 tctattgttc cattaccgat aactttttgc tcaaatgctt gtttctctgc agccaaaccg
    55921 acaaaatccg tattgctact cttcaattcc acaccaatac ccgtcaccgt aaaatctggt
    55981 ttttcttcga tcctatactt tgccatttct cccacccttt ctattatatt aagttcatct
    56041 tacataaaat taaagggaaa tgacacgatt acgctctttt ttctagggat atttttattt
    56101 tttaactatt tttttgcttt cactgcaatc caaatctcac tgtaaacatt actgaaatcc
    56161 tctccccatt ttgtaaaaga gatctcggga gcttcgacta acccataatc tgaagaagga
    56221 agccattctg catagatttt cccccaagta tcttgtaaag tttggggaaa tggcccttta
    56281 ttaggaaaaa tggcccaagt gtgttcttct atagcaagca tttctaaatc agcgtacgga
    56341 ttttcttttg tcgtagcaaa gccaatcatg tgcatcaaac tgcccttttc ttccaagcgg
    56401 tctccatcaa atccataaga aacgttgatt acttgatttg gatataaatc tcctaactta
    56461 tgcatctctt ccctttgagt ctccgtgatc gtctgcgcta acttttgtat ttcttgattg
    56521 actccttcaa atttgacagg aacttttttc gccacacctg ccacataaaa ctgttctttc
    56581 ttttcgatac gaaattccat cgattttcct cctctgacat caataaaaaa tgtcaagcgt
    56641 ggaaaagatt tttgtatgcc gtatctactg atttctgaag gcagatatcc tgaccaatca
    56701 cgaaaagctc ttgaaaaacc ttcgactgtt tcatatccat atctaaacgc cgtttctgtc
    56761 actcttgatc catctagaag atcgcgatta gccaaagcca atctacggtt tttgatatag
    56821 tccattagcg acatccctgc aataaacgta aagatgcgtt ttaattgata ttcagagatt
    56881 cctgtatttt cggctattat tttataggaa agtccttctg tcaaatgttc ttcgatgtaa
    56941 tcgatcaatt ggttcagatc tttaagcata tttatcttcc tccttgattg cctttttatc
    57001 atattatcaa agaaagtcaa ttacttgatg aatcaggaac caatttagtc agatgtagaa
    57061 aatgttgtat ggatctaaag aaaattctca agcagcgttt cgtaacggat aattggtatt
    57121 atctgcctat ctatgtttta cctttagaaa aataaatttt ggggaagaca gattctaagt
    57181 aaacaaagcg gtaaaaatat cttttattcc cttagttaat ccgcttacta cctactgtac
    57241 aaagcaaatt gttgttcaaa ctgctgatca gaacgctgct tggatttttc tttgcgatac
    57301 atcatacctc ttttatcaat tggaacaatt atttatttct aacaaaatca cttcattttt
    57361 gtcagataaa taaaaaacaa aaaaagttcc atctttaaaa cacgctattc ttttactttt
    57421 tctcacattc tctaagaaaa gaaaaggaga atgaattttt gacaattcga gcaaaagtga
    57481 ttatcaaata tgtaaaatca gctacttttt tcttaaacgt ttctttatac taaatataaa
    57541 taagtgtttc atgaaaggag aactagatga ataattggct tgagtatttt cctgaaaacg
    57601 ttttggaacg cggttacagc tatcatctgc acggttttgt ccgtcatttg aactatacaa
    57661 gcaagtactt gtccgcaaca gtttctggca cggaagatta taaggtagtg atcacttggg
    57721 atgaaaagac caacatgact tgtgattgtc tatatgccat agaaggaaaa aaatgcaaac
    57781 acatggctgc tgtcttattc gcttacgaag aacgtccaat aaaaaaatcc aactactcac
    57841 tttccgaact ctcgtccctt gtttcctccg ctagttcctc tcttgtacgg gagcttttaa
    57901 cagagattct tatagaacat ccgcacttta tcgaacgctt caaagttaag atgccatttc
    57961 atgcaataaa ttattcagat aaattaacaa ctatcatcca taaatacgat catattatca
    58021 agaaaaacaa aaacaggaaa acagcgaagt tcatcatgga gatgcgaaag ttcatccaag
    58081 aagcagttga atcgcttatt cagcaaaatg cctatcttcc cgcattcgaa ttgatcaatg
    58141 aagtgattgc tactctcgaa acattctatt gggagcctga ggatgaacga acccttcttc
    58201 tgatagagga ctgttattat ttatggaaag aattattagc agaagcacct catgcagaaa
    58261 aaaggcaaat gttctcttgg ttcgtctgcc aagtcgatca tactgacgcc tcttattcaa
    58321 aacgctactc tataaaaatc ctgaaagaag actttcggga aaaagaattt tctaaccaaa
    58381 agaaaaaaat agataaaaaa ctaaagaaac ggtaaagaaa gacgatttca atgaaaaata
    58441 gcaagtaaac gataacaacc atcctaaatc cacaagaaat acagcagacc ttgctttaaa
    58501 aacacgaatc atgcaaagga tgaagtaaag aagacttaac gcgtacccaa tattagtcat
    58561 ttgactatta ggtacgcgtt ttgttttata agtcatgaca aatttccttc gttgctggat
    58621 agattttccg gcattgttga tagattttat gatacttttc tacattttgt aagagaggtt
    58681 ccgctgcatc tgtatattgg ataaaattct gacaacaact ttcaggtgtg tcgaaccacc
    58741 ctaaccctag tgcagcaatc attgttgcgc ctaatgcagg tccttcctcc atacttaaac
    58801 aatagaccgt tgcatcgaaa atatcagctt ggatttgtag ccatgcaaga tttttcgcgc
    58861 ctcctcccac cgaaacaata cgtgtaaatc tgcgacccgc tagttcttta cgtttcaatc
    58921 ccaccattga caaatgctca ttaaaaattt agaatattca caagtttaac gacaattatg
    58981 aaaatttatg tcgtgctaaa ggagttttgt tattggatga aaagttagat ataaaaactg
    59041 cgatcaaaga cacgttacct accgttttcg gttatatcgg tattggactt gcatttggta
    59101 tcgttgggaa agctgccgga tttcatccac tagtcgtcac gttgatgtcc ctgctggtct
    59161 atgctggttc tgcccaattt atcacagtca gcatgcttgc tagtcacagc ccattgcttt
    59221 ccatcgtttt ctcgaccttt ctagtcaatt cccgaatgat tctgatgagt atgacgattg
    59281 ctccttattt caagaaaaat cggctgcttc aaaatctgct gattggcaca ttgctgacag
    59341 atgaaagttt cgcactggga atgaataaat tgaactatac tggacaaaag ttaaactttc
    59401 gttggatgaa tacagctaat tggatttctt atttgacgtg ggtgggttct tctcttgttg
    59461 gcgcactttt agggaatttt attactgatc cgaaaaagtt tggtttggat ttcgccatcg
    59521 tcgctatgtt tatcgggtta ctttatcttc aagtcatttc tgatagaaac acctctaaac
    59581 gattacagtt gatcctgatt ggtctcactt tgattctggt atatgtcgga ctgattttta
    59641 tcccaagcaa cttagtgatt gtagttgtaa cactgattgg gtgcggattg ggggtgtgga
    59701 tcaaacatgc cttcttttga gtttacattg ctgactattt taggttgtac tttagcaact
    59761 tggctttcta gggtcctacc atttgtctta ctgaaaaaat tcgatttacc gcaaccgttg
    59821 cttgagtatt taagttttgt cccgatcgtc attatgtctg ctttatggtt cagcagtcta
    59881 tttacccaaa atatcggaca tctgccgcag atcaatctcg aaaatgcttt ggcttcagtt
    59941 cctacacttt tagctgctat tctttcaaaa agcttattgg tgatcgtctt ggcaggaatt
    60001 ctttcccttt cgttgattcg cttattataa ataaaaaaac aagagcttat ggcaaattac
    60061 tgtcatgcgc tcttgttttt atcaaagtca aataagaaaa aaatcggcgt attcttgctt
    60121 atccgttgaa cggaccacta acaacgactt ttcctaacat atgtcctgtt tctacgtctt
    60181 tggttgcttg tttcaagttc ttcgcattca tcccatctga atagaccttg ctcaatgtac
    60241 tgcggataat cccttcattt gctaaagcag caatgtgcgc taaagcttct ccttgcgttt
    60301 cgatttcata gttatagtct gttttagcga acatatactc ccagtcgaag ctgatagatt
    60361 ggtttttcca aacacctata tctaacggct ctttgatccc tacgatcgtt cccacatgtc
    60421 caaatggtcg gacaaggtgc ttgatttgat caaagtagcg ggtaatatcg aataatacag
    60481 cgacatactc tacttgatcg attcctaatt cacgaaaact tttacttaag tcgtgatgat
    60541 aatcgattgg atagtctaca cctgtttttt tcagccattc aaaattcttc ggacttgcag
    60601 tcgcgtagac ttctaggcca gcccaatgcg ctagttgatt caaaatcgaa ccgacgcccc
    60661 cggatccgtt gatcactaag atttttttcc cgcgattggc attttcttct ggagttagac
    60721 caaatttttc aaataacaat tcataagcgg tcaatgaggt caacggcaag gctgcagctt
    60781 cttcatctga aagatttttt ggtgcaagag cgacaatacg ttcgtcaact agttggtatt
    60841 cttgattgct tcctgctctt gttgttgtac ctgcgtaaaa aacgcgatcg ccgacagaaa
    60901 atttttgcac ttcgtcacct acagcaacaa ctttcccgac tccatcaaaa cctaagatac
    60961 gtaaagcatt tcttatcccg ttatcttggc gaagtttcgt atcgacagga ttaacagata
    61021 ctgcgttgac ttttaccaga agatcccgtg aactgggtac aggtatctgt tctttttcat
    61081 caataaagct ttttggatca tcgatcggca acccttcata aaaaccgact accttcatta
    61141 attccttttc tgacatacga attcctcctt agcttcatca agttggagca tccatacagt
    61201 gttcatttca atatatatag tatgctattt gttccacctt ttttattcat cataattatt
    61261 ctcttactta aagtaaacta tttgcacttt tttggttaaa aaagaggttg cgacaagact
    61321 tttgtcacaa cctcttataa acggtgttct cctaccaact cttcggtcac aagtcaaaat
    61381 attcatcaaa catgagaagc tgttttttga aattgctcct tgtgactcag agttaaacgg
    61441 caggctcaca acctctgata taaacggtgt tcaatcaact gaccctcggt attagctcaa
    61501 aaaacgacaa aatatgaaga gctatttttg tttggctgtt cttattactt gatacaggac
    61561 agctttttca cgacctctaa ttcacggtgt tcaagcaaga aatcattgtt cactgaaaag
    61621 cgttggatgt tctttttcaa aggtctctaa gatctctcgt acttcatcag tagatttcgt
    61681 attcatcaac tgaactcgca agtcatttgc tcctggaaat cctttgatat agattttaaa
    61741 gaaacgatgt agtcctgtga tggaacgcgg gatgatttct gaataatgat cttgcagatc
    61801 tagttgcaga cgaagtagtc cgatcagttc tttttctgta tgttccctcg ggtctttttc
    61861 aaatgcataa ggattcttga aaatccctcg gccaatcatg atgccatcaa cgccatattt
    61921 ctcggccaat tcttctcctg tctggcgatc ggggatatct ccattgatcg tgattagtgt
    61981 ttgtggagcg atttggtcac gtaaagcaat gattttagga atgacttccc aatgtgcatc
    62041 tactttactc atctctttac gcgtacgcaa atggacagaa agattggcta tatcttgatg
    62101 aagtaggtga ctgatccatt cttccatctc agacatttcc gtatagccga tacgcgtctt
    62161 gacgctgaca ggcaaaccgc cagctttagc tgcttcaatc aattgtgccg ctacttctgg
    62221 acgaaggatc aagccactgc cttttccacg ttctgctaca ttagggactg ggcagcccat
    62281 gttgatatcg attccttgga agcccatttc tgccatagca atgctcattt ctctaaaaaa
    62341 ttctggcttg tctccccaaa tatgggcaac catcggctgt tcatcttctg taaatgttaa
    62401 tcttcctcgt acactgtctt ttccatctgg atgacagaaa ctgtctgagt ttgtaaactc
    62461 agtaaagaag acatccggtg ctgctgcatg ctttacgaca tggcgaaata caacatctgt
    62521 tacatcttcc attggtgcta aaacaaaaaa aggctttggc agctctttcc aaaaattagt
    62581 agtcatttat ttgttactct ccattctatc aagcagtgaa gtcgcaatct ttctcaaaaa
    62641 cattgtcatt atactaggaa acaaaaaaag aagcaaagtg aacagcttaa aagatgtttc
    62701 tgattgagca aaaaaaagac tgtgacaaaa atcttatcac agtccatttt ccggaataaa
    62761 tggtgttcaa aagcttgcat ttgcggtaat aagtccaacc aaacgaaaaa taggaggagc
    62821 tatttttgtt tggctgttct tattacttga tgcagaacag ctttttcaca acctctccac
    62881 taaacggtgt tcaatcagct gaccctcggt attcgctcaa aaaacaacaa aatatgagga
    62941 actattttcc cgtttgtttc tctaatactc aggtcaaaac gctgatttca caacctcttt
    63001 tctaacttct caatcctctt cctttattga tcaaatacca agtaacggcg tacaaaacaa
    63061 cgatgaataa cacaagtacg atcatcgatg ttgctactgg cacatcgatc gttccaagga
    63121 atccgtaacg gaaaccggag atcatataaa cgatcggatt gacttttgaa acagcttgcc
    63181 aaaagggcgg taacatagag atggcataga aaacgccacc tagataagtt aacggctgca
    63241 agacaaatgt aggcacgatc gatacatcat cataagactg agcaaaaatc ccgttgagca
    63301 gtcctgctaa tgaaaacaag attgccgtca tcaataatgt aatgatgacc atgaaccatg
    63361 aatacacatg aagtggtaca aagaacaagg aaatgatcgt tacgagagag ccgacgagaa
    63421 tactgcgacc cacaccacca atcacaaagc cccaaataat cacatgcgta ggaacaggtg
    63481 ctaccaagat ttcttcgata tttttctgaa atttttgaga gaagaaggac gaagaaacat
    63541 tggcatacga actagtgata gcagacatca taatcaaacc aggaacgatg aattccatat
    63601 atgaaaaacc acccatgtca ccgatccgcc caccgatcat ttttccgaaa ataacaaaat
    63661 acaaggatgt cgtgatcact ggcggaacca gtgtttggac ccatatacgc aaatagcggt
    63721 tcgtttcctt gatagctaaa ctttttaatg cagtaaaata aagattaaac atttttctcc
    63781 tccgtatgat tattttcttc tgtgattttc aagaacagtt cttctaaacg attcgactta
    63841 ttcctcatag aaagaacttt gattccttgt cttgtaagct gatcgaagat tccgttcacc
    63901 ccttgatttc gttcaacttc gacagcgatt gtctgctcat cttcaaatgt acaagcatat
    63961 ccttcaatca caggtttggt atcatatggc gctaaatcaa agataaatgt ttcaaattgc
    64021 agttttgaca gaagctcttt catacttgta ttctcgatca gttcacccga ttggatgatt
    64081 ccgatgttgc gacaaagcat ttcagcttct tctagataat gcgtcgtcaa aatgatcgtt
    64141 gtaccatttt cgttcaattc tcgtagaaac tcccacatct cgcgtctcaa ctcgatgtca
    64201 actcctgctg ttggttcatc caagatcagc aaacgtggtt catgcatcaa tgccctagca
    64261 atcatcagtc ttcgcttcat tcccccggaa agcatacgtg cacggacatt tctcttttcc
    64321 caaagattgg actgcttcaa atatttttcg ctgcgtttca tcgcttcttt gcgagagaca
    64381 ccgtagtagc ctgcttgatt cacgacgatt tgctggaccg tttcaaaagg gttaaaattg
    64441 aactcttgtg gaaccaatcc aatctgttgc tttgctcgaa ctagatcctt gtccagatca
    64501 taaccgaaga cattcacttt tccagatgtt ttattgacta aagaagtaat aatcccgatc
    64561 gttgtagact tcccagctcc atttggccct aatagcgcat agaaatctcc ttctttcacc
    64621 gaaagatcga ttccccgcaa tgcttcgacc ccacttccat agatcttttt caaattattt
    64681 atttcaagcg catttgccat ttatttccta tctccttata gacatgattc ttaattgtat
    64741 catggaatac agcagatgaa aaaacaactt ggcttccaca caaaaacaca cctgctaaca
    64801 aagaggagat gtgttttcta gttcatgatc atcttcgata gaataactat ctaaacaact
    64861 ctggaacttt taaaatcata aaagtaccga cagcaactac tacgatgaca tatagaagat
    64921 ccttataact gaggttcttg tcttttttat tcatgttaag ctttcctccg tccttttatc
    64981 gaaagctttt ttcttttatt ttaaccgaaa taaataaaat ggaaatagtt attttcaatt
    65041 tctgttttcg ctgtttgttt tacggagaac tttgccatgg aacgtgcgtc tcgtcgctga
    65101 tgctaagttt tttcgataaa agctgctaga aggaagacag cgtggtttat tttgtatcgt
    65161 cttttgctaa atcttccaag atcatctgga cagcagactc gttcccattg aattctgcca
    65221 cttttttggc atcaatgtac ttcttttgat aatcgtcttt ttggacccac gcatcatgct
    65281 tcgtttgata aagttaatca aacggatacc actgacgctg ttcatcgaac aacaaacttt
    65341 ctttttgggc ctgttcaact atggatttag gataattcaa aactttcagc aaggcaatcg
    65401 catttcgggt ccttgaaggt ccttctttta atttgaaatc aaaactgatt ccttttcctt
    65461 ctgttacttg ttcttcaaag tggacattct cacaataatt ctttaaaatc tctgtcaatt
    65521 cgatatcatg tgtggcgaca aatgctaaag atggatactc cgcaagccac cgaacgactg
    65581 aagcggaaga agcaatccgt tcgatcgtat ttgttccttt taaaatctca tctacgaagc
    65641 agtagcagcg ttctttggaa gccacttggt ccagcaaacg tttgatcgat ttgatttctg
    65701 aaacaaaata actgtcgcct tcaaataaat catcttcgat tgccatggaa gtcaacacat
    65761 gtccaggttg cagggtaaac tgttctgcaa tcgctgtttg gatcgtctgt gctagaatac
    65821 agctgatggc tatacttttg acatacgtag attttcctga tgcattggaa cccgtgacta
    65881 atgtattctt ctgccagttg actggattaa ctaccgcttc ttttaacaat ggatgataga
    65941 tatctttcgc tgtcacaccg ccctcagtaa actctggtcg gcaagtgatc ggcatatagg
    66001 tgcgataatt caaaacggct gctgcaactt ccaattctcc cagcaattcc cacagcttga
    66061 tggcttcagt tgaatgcttt tctaatttag tgagaacgaa atgataggag ataaatggca
    66121 gcatgaacat gatgttgaca tattcaaaaa tcaattctgc ttcactcccg ctcttcattc
    66181 gaaatgaaaa acctaattta gggatgtctc ttaatggttt agtttgctgt ttcagctctt
    66241 tttgaagtgg tgtcgtcatt tttgctaact gattggcggc tgaaatcgtt gaaaccaaat
    66301 aactcatgct attcagctct gtttctagtg tttgtttctt cactagataa tagaccgtat
    66361 tgaatactaa gccaccgatt gctagataga ttcctagtac ttgccctaaa agaagcaaac
    66421 ctacacccac cagcggaagc aagccaagaa aaataaataa acctacgcgt ccaatctttt
    66481 tactttttcc atccgctaga tattgttttg caaaattatg atcttttttt cctaaacgag
    66541 cgaattgata ttggattctt tctctcagtt gaggattttc ctgataaaaa gcaattagtt
    66601 tttctaactg ataatcttct ccaaaatcaa agctacgtaa acgctgatac aacgcttctg
    66661 aacctacact agaataggta ctgttgatcc cttcaaatac ttcgaacata tccaagtcat
    66721 accaagtaag atcgtcgatt tcactatccc atgaacggaa ttttttctcc gtgagccacg
    66781 catccttcaa actttcttct ttatcaaatc tcggttgata aggaattttt ccccaattac
    66841 tacgaactgt ttcctttact ttcaaacgtg aaaaaatgtc taaaacaact aataaaataa
    66901 caactgcaat aataattaaa acgataaatt ctctttggcc catatccctc tccgttcctt
    66961 gatttgttag ttttagtata gcactgttgc gctatttgaa aagggggtac aaaaataact
    67021 gtcttcgtta cctaattcgt atcaatcaca ccaaaataaa aacaccttcc aaaaaagaag
    67081 atgtctttaa aacgagatac aattttttgt cattcacttc aggtaaatta gagccaatta
    67141 aaccctccgc aacttgacgg agatggagaa gatgcccccg tctaatctag cggtcatctc
    67201 tcctcccatt ccttccacca atttttttga caggtaaagc ccgattccgc tagattccgt
    67261 atttgtgcgg ctggtatttt cggtataaaa acgctggaag actttttcaa cagaggtttg
    67321 cgctcctggt ttgataggat tggccactgt taatcgaatg aatgaatcct cttttgaaaa
    67381 tgtcaccttt gcttgtccat ctgcataacg caataaattc tgtatgatat tttgcagcac
    67441 tcgcagcaac atgagcggat ctgctaatac agttgtattt atcgagtgtt cagcgaacgc
    67501 tacctcgata tttttctcag aaaattgttc ataaaaagag aaaaatactt cttccacctc
    67561 tttagaaaaa gaaagcgtat ggagatccat ttctttttgc ttcgtctcta ttcgagcaag
    67621 atcataaaac tgatccgtca tactgagtaa tcttgcaaca gattgtttga tgatcgttaa
    67681 atacttctcc cgtttctccg tatcctctac ctgttccagt aattgtacat aaccgttaat
    67741 agcagtcaaa ggagttctga gatcatgaga aaggccgacg atcgatagtc tgatgttttc
    67801 ttccatttct tgaaatgctt gtcctttttg ttcattttca tccacccatg tattcagtgc
    67861 atctactagg tccattagat tcttttctcg aaattcgact gaaagacgac caccatattc
    67921 ttgtcgttca gaaagagtgg cgattttctt agttaatctc ttgatttccc tttgcaggaa
    67981 gaaaataaaa cttcccataa agataacaac gagaagcaac agccacttaa tcaaatctaa
    68041 accccactcc ccacaccgta tgaatataca cagcatgtgc ctttgctagt ttccctcgaa
    68101 gattggaaat atgcatattc actgttttct cactatcaaa atatggttct tgccaaactg
    68161 tttcataaag atttgctcgc gaaaatactt ttttcggatg ttctaaaaaa agcttcagca
    68221 gatcgaattc tcttcctgtc aaatggacag ccacaccatt cacatttaca tccctcgact
    68281 ctttgtccag taagatttcc ttgtaataga tgcgttgcga cagatctttt acttggacag
    68341 aagtctgatg acgaagttgg atgccgattc gtaacaacag ttcttcgata tcaaatggtt
    68401 tcgtcacata gtcatccgct cctgctgcca acaaggaaac tttatctctt tgatcgcttt
    68461 ttgctgaaag aacgatgatc ggaacattcg atgtctgtcg gatttctgct aacaatgctt
    68521 cacctgaaag ccctggaagc atgagatcta gaaggatcaa atcgacagga tatgtgctta
    68581 acaataattt tccttccgta cctgaataag catcaagaag tttgtatctc tgttcaagaa
    68641 cctcctccag taaagaatga acagcttcat cgtcttcgat aatcaaaata gtttccagca
    68701 ggaacaccta cttaatgtca gatttttgga aaataaacat tcctagagct gatgatacca
    68761 cgattgttac tagactgacc agaatcattt tcggtgcttg cgaataagtt gcttgttgcg
    68821 caaagtccgt atacatgagc cacgtttccg taaaccactc cgttagaaat tccaagcctt
    68881 tgatttttgc gaaaacaccg ggaacgaagg ccgttcccat gatataaaga aaagaaagaa
    68941 gcaaactgac actggtactt ctagtgatga atgtcaaagc cactggaaca gataatgtcg
    69001 ctaatatcag cagaagcaat acaggaaata cttttagaac ataatttcca tagtttttga
    69061 ttccctcaac ttcaccaaat ccgaaagcaa gtgtgtaagc aatcatggct agccccgtaa
    69121 tcaaaaccac gccaagtgtt gtgatcaaaa gcgtaacgag aagtttcgac acataataag
    69181 tcattcgatt ccgtcctaaa gataacgtat tgcgaatcgt accgttttga aattcttccc
    69241 caatataaaa gcacgcaaat gctgcgaaag ccagaagaat ccatgcagcc attttttcca
    69301 ccattaaaat ccctgttgca ccgttgatga ctgtatccgt tgcttggttt aattcattgc
    69361 cgtattttgt atgcatatac cattcgttcc aagaataaaa aagcggaagt acgaccatca
    69421 gtcctagtga gacccacatt ttacggctct tccatacttt tattttttca gcagttaata
    69481 gattaaacat gtggattgcc tccagttaat tgtaagaaat aatcttccag tttttgccca
    69541 actaggtgga taccatccac aggaactttt gcctctacca atgcttgatt gatggctgct
    69601 acttggtcaa ttccttcaaa aagctggata acacggctag attggacaaa ataatcccta
    69661 taaccaagag agtcgagaac cgttactgct tgttccgtcg ccgaagtgtc aatttttata
    69721 aattgacgag attcttgtgc caattcttct ttcgataatt ctttgatcaa gtgtccttca
    69781 tgcaaaatac cgtagtgagt ggcgatctgt gacaattcat ctagcaagtg gctagaaagc
    69841 aagacggtga tgccccgttc ttttaccaaa cgttggatga tttctcgcat ttctgccatc
    69901 cctgctggat ccatcccatt cgtcggttca tccaaaatca aaaattctgg attcgtgatc
    69961 agtgcatttg caatagctaa acgctggcgc atacctaaag agaaattctt tgctttcttt
    70021 ttccctgtat tttccaatcg catcattttc agcaggtctt cgatttctct atccgacaca
    70081 ccgccgttcg ctgcttggat acgtaggtta tctcttgcag ttaattctgg ataaagagca
    70141 ggggtttcaa tcgattgacc catacgtcgt cttgctgcct gcaaatccgt cgttccaaat
    70201 aattcgatcg aaccttcatc aatcgagatc aaacccataa tagttctcat aaaggtagac
    70261 ttacccgctc cattctcccc aatcaaacca tagatcattc cacgtttgat ttcgatcgat
    70321 actttatcta atgctttggc agcaccgtat tttttggtta taccagttgc tttcaagacc
    70381 gtttcatttc caaaatccat acttatcctt ctttcttatt gataagtgaa gtatagttga
    70441 cgggtataaa gaaagcagcc agaaatgtat aaagaaagtg taaattttcc aattgaattt
    70501 caagaaaaat cagactgtct cgcagacgtg gttgagttgt ctgccaatca aagagcgcac
    70561 caaacagtgc taatccaagt ggactggcca ccatggtaat cgttgttatc gttgacatca
    70621 gacgtccttg tatatgcgtt ggaacttctc gctgaagcca gaccatataa aaagcaaaag
    70681 aaaacattaa tccttaaaaa cggacttatg aaaaataata catgccgttt gggatttaca
    70741 attagctacc aaataagagg ttatgacaaa agacttttca caatcccttc ttccgaataa
    70801 acggtgttct cctgccaact cctcggtcac aagtcacaat atttatcaaa catgagaagc
    70861 aatttttgta aattccttct tatttcttga agctgaccac ttctgtcaca acctcagaag
    70921 cggataaata atattgtttg atgatacttt atctttttcc cgtttgttta tagatcgaat
    70981 gatattatag accaagaatc ctacctatta acatagctaa aaacacaaaa aaggcacttt
    71041 ccaaattgtg gaaagtgcca gaaaagttag gattaaggta actgcgctca gcattgcttc
    71101 gcccagtacg attctcgtaa ctcgtgaact cgaacgataa tcgcaattaa cgttttgaga
    71161 actgtgaagc tttacgggct ttcttaagac ctggttaaac aaaactctat tttattgcat
    71221 tttacaggaa tgtatttcat gcgaaattaa taagtctttg tttatagagt tttactaggg
    71281 tataaaaagt tgtatgttat cattacctca aaacattacc tcagcttggc gagttggttg
    71341 attgaagaat aaatcattta tctagatatc tcaataaaaa atgatttcta agaaacttgt
    71401 attttcgtgt tattattttt ttgccctatc aaaatttcta attcttctag cgtaatatga
    71461 ttatgacaca taatcgattc aattacttca atacctattt ttttcgagaa agatcccttt
    71521 tgttcactca caaaaatact ttcagaagac atatataagg aacgaagttt tggaattagt
    71581 atatcgtaca aatagaccac cataaaatcg tccttgcaac cattctcaaa aagaattaaa
    71641 tttgctgatt gtgttacata tatcactgaa ttacattcat ggtcaattcc aaaaacaatg
    71701 tctacttcat tttcttttct aattcgcgca gttacatttt tcaaactttc accattactt
    71761 ataaatgctt tagttactgt aagctctgat gtttgttcag atattccttt tataatattt
    71821 tgttcatcag ccacattccc cataaatccg ccgattcctt ttaagtaata attctcacct
    71881 aagagtcgct tgcattcact gaattgataa aaaaaccagt taaaaaaatc ttctggaaaa
    71941 ataaattctg atcgaacttt atttatattt ttagctccta ttaattttat aactcgatta
    72001 atgttcactt gctgcgatga acatataact gaataaattg agttgtttaa ttcaaaaaaa
    72061 caactttaac atatgcatca ttaattcgtt attttttagg tagatattga tcattgttat
    72121 ctctcttttt ttgcttccca tactccaact tagaaattgc cgttataaaa tttattttaa
    72181 aggtgacttt ttcccctgaa gtatcggtag taggaatact taatacctca gcttctgagg
    72241 aggtatccca attatagtta tactttgcat catcaccata aagaacaatt ccattttttt
    72301 tatcttgtgc cgttagcttt actggttcgc ttacttttct tgttaatatc ttggacttta
    72361 catcatcgat attgcttatt ttatcaagct taaataattt acaaattaat ttcgtactag
    72421 tttttatatt tg
//
LOCUS       DAXQKX010000005        71334 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.005, whole genome shotgun sequence.
ACCESSION   DAXQKX010000005 DAXQKX010000000
VERSION     DAXQKX010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 71334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 71334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71334
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.005"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(125..463)
                     /locus_tag="ACF3MF_000362"
     CDS             complement(125..463)
                     /locus_tag="ACF3MF_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HFE3926393.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            complement(479..682)
                     /locus_tag="ACF3MF_000363"
     CDS             complement(479..682)
                     /locus_tag="ACF3MF_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3926394.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            complement(698..1474)
                     /locus_tag="ACF3MF_000364"
     CDS             complement(698..1474)
                     /locus_tag="ACF3MF_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HFE3926395.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKERYYPQMDLEEIG"
     gene            1554..1724
                     /locus_tag="ACF3MF_000365"
     CDS             1554..1724
                     /locus_tag="ACF3MF_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926396.1"
                     /translation="MNKKIAADLVVAWLNHESQVSTKGESISPKEIAQAYLDIHYAVI
                     YGQLPEDRKNDD"
     gene            complement(1721..1861)
                     /locus_tag="ACF3MF_000366"
     CDS             complement(1721..1861)
                     /locus_tag="ACF3MF_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926397.1"
                     /translation="MEKTVSAKIEDLKLDILKQAKVAMEHAVDKEDSAMVAAIAEILA
                     HV"
     gene            2162..2482
                     /locus_tag="ACF3MF_000367"
     CDS             2162..2482
                     /locus_tag="ACF3MF_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFE3926398.1"
                     /translation="MNPYEKIKELTKQNGISVRELEKRLGYSNGYFSKWKSVSPNSEG
                     LAKVSDYFGVSVDYLLGREKKETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            2500..2931
                     /locus_tag="ACF3MF_000368"
     CDS             2500..2931
                     /locus_tag="ACF3MF_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HFE3926399.1"
                     /translation="MYLKLKEMLSGYNLKLIYMEMEEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            3060..3644
                     /locus_tag="ACF3MF_000369"
     CDS             3060..3644
                     /locus_tag="ACF3MF_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HFE3926400.1"
                     /translation="MAKKVMGQDGKMYKVSKPFYKKVWFWVLAVILIIIIGSALNGGS
                     DSNKASDNGGEKVTKSSTSASSSKEEKSDTFYKIGDTVKVGDAEYTLNSVELTDERNQ
                     FEENQPAQVVKITYTVKNDGDSDLPVGTDVEVYGPDDKKSETYANENTMGAVAPGKQM
                     DVTAHFTLNQTGEIEIHFSPLVSFEKAAIFKATV"
     gene            3758..4897
                     /locus_tag="ACF3MF_000370"
     CDS             3758..4897
                     /locus_tag="ACF3MF_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFE3926401.1"
                     /translation="MARFVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(4966..5039)
                     /locus_tag="ACF3MF_000371"
     tRNA            complement(4966..5039)
                     /locus_tag="ACF3MF_000371"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5003..5005),aa:Arg,seq:cct)
     gene            5193..5357
                     /locus_tag="ACF3MF_000372"
     CDS             5193..5357
                     /locus_tag="ACF3MF_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926402.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            complement(5428..6609)
                     /locus_tag="ACF3MF_000373"
     CDS             complement(5428..6609)
                     /locus_tag="ACF3MF_000373"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFE3926403.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(6732..7145)
                     /locus_tag="ACF3MF_000374"
     CDS             complement(6732..7145)
                     /locus_tag="ACF3MF_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HFE3926404.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            complement(7145..7327)
                     /locus_tag="ACF3MF_000375"
     CDS             complement(7145..7327)
                     /locus_tag="ACF3MF_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HFE3926405.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            complement(7358..7579)
                     /locus_tag="ACF3MF_000376"
     CDS             complement(7358..7579)
                     /locus_tag="ACF3MF_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926406.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            complement(7647..9107)
                     /locus_tag="ACF3MF_000377"
     CDS             complement(7647..9107)
                     /locus_tag="ACF3MF_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFE3926407.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGPNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            complement(9215..9535)
                     /locus_tag="ACF3MF_000378"
     CDS             complement(9215..9535)
                     /locus_tag="ACF3MF_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFE3926408.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            complement(9565..9882)
                     /locus_tag="ACF3MF_000379"
     CDS             complement(9565..9882)
                     /locus_tag="ACF3MF_000379"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFE3926409.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            complement(10034..12736)
                     /locus_tag="ACF3MF_000380"
     CDS             complement(10034..12736)
                     /locus_tag="ACF3MF_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFE3926410.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            complement(12799..14076)
                     /locus_tag="ACF3MF_000381"
     CDS             complement(12799..14076)
                     /locus_tag="ACF3MF_000381"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFE3926411.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            complement(14076..15089)
                     /locus_tag="ACF3MF_000382"
     CDS             complement(14076..15089)
                     /locus_tag="ACF3MF_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFE3926412.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            complement(15105..15833)
                     /gene="sfsA"
                     /locus_tag="ACF3MF_000383"
     CDS             complement(15105..15833)
                     /gene="sfsA"
                     /locus_tag="ACF3MF_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HFE3926413.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            16010..16339
                     /locus_tag="ACF3MF_000384"
     CDS             16010..16339
                     /locus_tag="ACF3MF_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HFE3926414.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            16523..17170
                     /locus_tag="ACF3MF_000385"
     CDS             16523..17170
                     /locus_tag="ACF3MF_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HFE3926415.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            17185..18711
                     /gene="zwf"
                     /locus_tag="ACF3MF_000386"
     CDS             17185..18711
                     /gene="zwf"
                     /locus_tag="ACF3MF_000386"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HFE3926416.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKTWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(18760..21558)
                     /gene="ileS"
                     /locus_tag="ACF3MF_000387"
     CDS             complement(18760..21558)
                     /gene="ileS"
                     /locus_tag="ACF3MF_000387"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HFE3926417.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKSYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(21820..22527)
                     /locus_tag="ACF3MF_000388"
     CDS             complement(21820..22527)
                     /locus_tag="ACF3MF_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HFE3926418.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            complement(22548..23330)
                     /locus_tag="ACF3MF_000389"
     CDS             complement(22548..23330)
                     /locus_tag="ACF3MF_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HFE3926419.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            complement(23379..23600)
                     /locus_tag="ACF3MF_000390"
     CDS             complement(23379..23600)
                     /locus_tag="ACF3MF_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HFE3926420.1"
                     /translation="MVYALLSWFPGGYQSGLGRLLAKICEPYISLFDRLPLRIGPLDF
                     TILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            complement(23681..24280)
                     /locus_tag="ACF3MF_000391"
     CDS             complement(23681..24280)
                     /locus_tag="ACF3MF_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HFE3926421.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            complement(24294..24971)
                     /locus_tag="ACF3MF_000392"
     CDS             complement(24294..24971)
                     /locus_tag="ACF3MF_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HFE3926422.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            complement(24988..26229)
                     /gene="ftsZ"
                     /locus_tag="ACF3MF_000393"
     CDS             complement(24988..26229)
                     /gene="ftsZ"
                     /locus_tag="ACF3MF_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HFE3926423.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            complement(26252..27577)
                     /gene="ftsA"
                     /locus_tag="ACF3MF_000394"
     CDS             complement(26252..27577)
                     /gene="ftsA"
                     /locus_tag="ACF3MF_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HFE3926424.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            complement(27733..28953)
                     /locus_tag="ACF3MF_000395"
     CDS             complement(27733..28953)
                     /locus_tag="ACF3MF_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HFE3926425.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            complement(28968..30056)
                     /gene="murG"
                     /locus_tag="ACF3MF_000396"
     CDS             complement(28968..30056)
                     /gene="murG"
                     /locus_tag="ACF3MF_000396"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HFE3926426.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            complement(30082..31443)
                     /gene="murD"
                     /locus_tag="ACF3MF_000397"
     CDS             complement(30082..31443)
                     /gene="murD"
                     /locus_tag="ACF3MF_000397"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HFE3926427.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            complement(31457..32419)
                     /gene="mraY"
                     /locus_tag="ACF3MF_000398"
     CDS             complement(31457..32419)
                     /gene="mraY"
                     /locus_tag="ACF3MF_000398"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HFE3926428.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            complement(32445..34637)
                     /locus_tag="ACF3MF_000399"
     CDS             complement(32445..34637)
                     /locus_tag="ACF3MF_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HFE3926429.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGIAYGVYSVPGYNVSAKTGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            complement(34638..35039)
                     /gene="ftsL"
                     /locus_tag="ACF3MF_000400"
     CDS             complement(34638..35039)
                     /gene="ftsL"
                     /locus_tag="ACF3MF_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HFE3926430.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            complement(35044..36003)
                     /gene="rsmH"
                     /locus_tag="ACF3MF_000401"
     CDS             complement(35044..36003)
                     /gene="rsmH"
                     /locus_tag="ACF3MF_000401"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HFE3926431.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            complement(36024..36455)
                     /gene="mraZ"
                     /locus_tag="ACF3MF_000402"
     CDS             complement(36024..36455)
                     /gene="mraZ"
                     /locus_tag="ACF3MF_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HFE3926432.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            complement(36625..36993)
                     /locus_tag="ACF3MF_000403"
     CDS             complement(36625..36993)
                     /locus_tag="ACF3MF_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HFE3926433.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            37164..38120
                     /locus_tag="ACF3MF_000404"
     CDS             37164..38120
                     /locus_tag="ACF3MF_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFE3926434.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            38193..38309
                     /locus_tag="ACF3MF_000405"
     CDS             38193..38309
                     /locus_tag="ACF3MF_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HFE3926435.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(38364..40046)
                     /gene="recN"
                     /locus_tag="ACF3MF_000406"
     CDS             complement(38364..40046)
                     /gene="recN"
                     /locus_tag="ACF3MF_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HFE3926436.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(40064..40513)
                     /locus_tag="ACF3MF_000407"
     CDS             complement(40064..40513)
                     /locus_tag="ACF3MF_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFE3926437.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            complement(40620..41438)
                     /locus_tag="ACF3MF_000408"
     CDS             complement(40620..41438)
                     /locus_tag="ACF3MF_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HFE3926438.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            complement(41447..42337)
                     /locus_tag="ACF3MF_000409"
     CDS             complement(41447..42337)
                     /locus_tag="ACF3MF_000409"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFE3926439.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            complement(42339..42563)
                     /locus_tag="ACF3MF_000410"
     CDS             complement(42339..42563)
                     /locus_tag="ACF3MF_000410"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HFE3926440.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            complement(42568..43905)
                     /gene="xseA"
                     /locus_tag="ACF3MF_000411"
     CDS             complement(42568..43905)
                     /gene="xseA"
                     /locus_tag="ACF3MF_000411"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HFE3926441.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            complement(43906..44760)
                     /locus_tag="ACF3MF_000412"
     CDS             complement(43906..44760)
                     /locus_tag="ACF3MF_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HFE3926442.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            complement(44857..45306)
                     /gene="nusB"
                     /locus_tag="ACF3MF_000413"
     CDS             complement(44857..45306)
                     /gene="nusB"
                     /locus_tag="ACF3MF_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HFE3926443.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            complement(45299..45724)
                     /locus_tag="ACF3MF_000414"
     CDS             complement(45299..45724)
                     /locus_tag="ACF3MF_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFE3926444.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            complement(45970..47034)
                     /locus_tag="ACF3MF_000415"
     CDS             complement(45970..47034)
                     /locus_tag="ACF3MF_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HFE3926445.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            complement(47206..47451)
                     /locus_tag="ACF3MF_000416"
     CDS             complement(47206..47451)
                     /locus_tag="ACF3MF_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFE3926446.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            complement(47590..47964)
                     /locus_tag="ACF3MF_000417"
     CDS             complement(47590..47964)
                     /locus_tag="ACF3MF_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HFE3926447.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            complement(48047..48961)
                     /locus_tag="ACF3MF_000418"
     CDS             complement(48047..48961)
                     /locus_tag="ACF3MF_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFE3926448.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            complement(48982..49785)
                     /locus_tag="ACF3MF_000419"
     CDS             complement(48982..49785)
                     /locus_tag="ACF3MF_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HFE3926449.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            complement(49818..50807)
                     /locus_tag="ACF3MF_000420"
     CDS             complement(49818..50807)
                     /locus_tag="ACF3MF_000420"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HFE3926450.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            complement(50910..51401)
                     /locus_tag="ACF3MF_000421"
     CDS             complement(50910..51401)
                     /locus_tag="ACF3MF_000421"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HFE3926451.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            complement(51592..54399)
                     /locus_tag="ACF3MF_000422"
     CDS             complement(51592..54399)
                     /locus_tag="ACF3MF_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFE3926452.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            complement(54833..55126)
                     /gene="rpmA"
                     /locus_tag="ACF3MF_000423"
     CDS             complement(54833..55126)
                     /gene="rpmA"
                     /locus_tag="ACF3MF_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HFE3926453.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            complement(55139..55483)
                     /locus_tag="ACF3MF_000424"
     CDS             complement(55139..55483)
                     /locus_tag="ACF3MF_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HFE3926454.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            complement(55510..55818)
                     /gene="rplU"
                     /locus_tag="ACF3MF_000425"
     CDS             complement(55510..55818)
                     /gene="rplU"
                     /locus_tag="ACF3MF_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HFE3926455.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     misc_feature    complement(55838..55914)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            56100..56741
                     /locus_tag="ACF3MF_000426"
     CDS             56100..56741
                     /locus_tag="ACF3MF_000426"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFE3926456.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     gene            complement(56803..58434)
                     /locus_tag="ACF3MF_000427"
     CDS             complement(56803..58434)
                     /locus_tag="ACF3MF_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015103 - inorganic anion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HFE3926457.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(58557..58916)
                     /locus_tag="ACF3MF_000428"
     CDS             complement(58557..58916)
                     /locus_tag="ACF3MF_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HFE3926458.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            complement(59075..59148)
                     /locus_tag="ACF3MF_000429"
     tRNA            complement(59075..59148)
                     /locus_tag="ACF3MF_000429"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(59112..59114),aa:Arg,seq:tct)
     gene            complement(59457..60140)
                     /locus_tag="ACF3MF_000430"
     CDS             complement(59457..60140)
                     /locus_tag="ACF3MF_000430"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HFE3926459.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            complement(60268..60786)
                     /locus_tag="ACF3MF_000431"
     CDS             complement(60268..60786)
                     /locus_tag="ACF3MF_000431"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFE3926460.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            60998..62842
                     /locus_tag="ACF3MF_000432"
     CDS             60998..62842
                     /locus_tag="ACF3MF_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926461.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
     gene            complement(62887..63891)
                     /locus_tag="ACF3MF_000433"
     CDS             complement(62887..63891)
                     /locus_tag="ACF3MF_000433"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017118 - lipoyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HFE3926462.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(63902..64642)
                     /locus_tag="ACF3MF_000434"
     CDS             complement(63902..64642)
                     /locus_tag="ACF3MF_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFE3926463.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            complement(64712..65515)
                     /locus_tag="ACF3MF_000435"
     CDS             complement(64712..65515)
                     /locus_tag="ACF3MF_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HFE3926464.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            complement(65515..66597)
                     /locus_tag="ACF3MF_000436"
     CDS             complement(65515..66597)
                     /locus_tag="ACF3MF_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HFE3926465.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            complement(66738..68006)
                     /gene="dltD"
                     /locus_tag="ACF3MF_000437"
     CDS             complement(66738..68006)
                     /gene="dltD"
                     /locus_tag="ACF3MF_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HFE3926466.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            complement(68009..68242)
                     /gene="dltC"
                     /locus_tag="ACF3MF_000438"
     CDS             complement(68009..68242)
                     /gene="dltC"
                     /locus_tag="ACF3MF_000438"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HFE3926467.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            complement(68287..69492)
                     /gene="dltB"
                     /locus_tag="ACF3MF_000439"
     CDS             complement(68287..69492)
                     /gene="dltB"
                     /locus_tag="ACF3MF_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HFE3926468.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            complement(69489..71003)
                     /gene="dltA"
                     /locus_tag="ACF3MF_000440"
     CDS             complement(69489..71003)
                     /gene="dltA"
                     /locus_tag="ACF3MF_000440"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HFE3926469.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            complement(71014..71163)
                     /locus_tag="ACF3MF_000441"
     CDS             complement(71014..71163)
                     /locus_tag="ACF3MF_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HFE3926470.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
BASE COUNT        20881 a        14979 c        11976 g        23498 t
ORIGIN      
        1 ctcagcttca tcaagcccca taaaaatcca aaccatgtaa acgattgtcc ctatcaacgc
       61 ttgtttgctt ccccaaagtc ctaaagcgta gatgattagt ggtgcgctga atactagtgc
      121 tctattaaat tttcccatcc gcttgcctcc ttaagatttc cgaaaaattt gtttctaaaa
      181 attcaagtgt tttacttctt aaaaatagat atgtgtctct tccttcaact ggataataga
      241 caaatccatt tttgtttttt tcgatatcga taatatttct atatcttggg ttctttaaaa
      301 ctctagaagt aaaccaatca tattttctgt taatccgttc tagtacttct ggcaacgtca
      361 tccatctacc agtatcatca gcttttttta actcctcata atccacttgg gagataatta
      421 catagccttc tggaattggg atttttgctt ctagatattg cattagctgt tcctcccttt
      481 acaattcgta catagtgata atcgaatcta taattctatt tgcttctgca gaagtctttt
      541 taccgtttaa aattaaagat aagtagcttt tgctaatacc gaatctttca gcaagcatgg
      601 tgtaagttaa gaattttgaa ctttcgacat attctttgat tttttctcta tctcgttgag
      661 tgatttctgc aatatcagtc attattcaac ctcctttcta accaatctcc tctaaatcca
      721 tttgaggata atatctttct ttttttagta attcgtagat aaatagacgc cctttctgtg
      781 tccatttggt attcattaca attttagtgc caccatcggc tttcggaatc tcagttgtat
      841 gagattttgt gtatccttgg ttcatgtgtt ttttgcacaa taaccattgg ttaccgactt
      901 ttttctgaat acctagttta tgaagtaatt tattcatctg ttgtggagac atcccataat
      961 ctgctgcaat ctgactaatt gttactgaat ctgtagaaga taatatgcta tctaaatagg
     1021 agattttagg ttcgtactct gcaatctttt gttctgcgat taatcttcca gttctttctt
     1081 cttttagttg agttgctaat tgaatgattg tatctggatt aagcaaagct tcttctactt
     1141 tttctggagt tagataacct ccatgttttc taattgctgg caacacttca cttgttaccc
     1201 aacgtttaaa ttttttggca gagggaagtt ttgattttaa gattaaactg tacaaaccag
     1261 attcgttgat gattgtcatc tctcttgatt gacctgaggt cgtgattcgc gaccccatct
     1321 tatcttccaa atctacatgc cgcgacaaag catctttagt gtttgaataa cccaaaacac
     1381 tcgcaacgtc tttgcctaca aaatatggtt catcatttac taaaattgtc cgaacttcgt
     1441 tttgttcgaa attaaaaatt tgcggtgtgt tcatatttct cattcctttc tttgatataa
     1501 ttttcttatc agtaagtggt ctactgaaat aatgcataag gtggtgaata agtatgaata
     1561 aaaaaatcgc tgcggattta gttgttgcat ggctaaatca cgaatcacaa gtatctacta
     1621 aaggcgaatc aatttcgcca aaagaaattg ctcaagctta tttagatatt cattatgctg
     1681 ttatctatgg tcagcttcca gaagaccgta aaaacgatga ctaaacgtga gctaaaatct
     1741 ctgctatggc tgcaaccatg gcagagtctt ctttatctac cgcgtgttcc atcgccactt
     1801 ttgcttgttt cagtatgtct aatttcaaat cttcgatttt tgccgagact gttttttcca
     1861 tattcttctc tcctttcttt tatattcgta aacaaattta acaacttttt tctaaattca
     1921 attgacaaaa catagagttt tattctatac tttgtacata gttaaataag acatataaac
     1981 attgatttta aaagctttct tggcggttgg cgtttaataa tcaaaagtgt tttttgttgt
     2041 ctttttagtt gttaaacttg tttacaagaa taagtataga gttttagctc taatttgtca
     2101 acagataaat agagtttaat tctatatttt ttcttgtcag tctagaaagg ttgacatatc
     2161 aatgaatcca tacgaaaaaa taaaagaatt aacaaagcaa aacggaatat ctgtaagaga
     2221 attagaaaaa agattgggat attcaaatgg atatttcagt aaatggaaat cagtatcacc
     2281 taactccgaa ggtttggcaa aagtatcaga ttactttgga gtctctgtag actaccttct
     2341 aggaagggag aaaaaagaga cccctaaaca tgtggattta tcagaagacg atactgtttt
     2401 ttcttttgat gggaaagaaa tatctaagga gacaatgcgt aaagcgattg caattgctaa
     2461 agctttagag gaaaatgaat agttggagtg atggtttgca tgtatttaaa gttgaaagaa
     2521 atgctgagtg ggtataattt aaaattgatc tatatggaaa tggaagaacc aggtttttat
     2581 tacccaaaac ccagaatcat ttttttgaat gaaaatctat acggtgaaac tgcagaagcc
     2641 tttcatttat ctcatgaact tgcacatttc agcgcctctc attttgaatt ttcagttttg
     2701 tacgatactt ctacaacttt tcactcaaaa tttgaaacag aagcagataa aatagctatt
     2761 ctaattttat taaatatcta tattgagaac gaactgactg atgaatctca gtttaatctc
     2821 gaaaaattta tggaatatta ttctattcag aataagctca gatacacttg ttatgctgtc
     2881 tgccaatgct attttaagaa aaaatattct tacgcaaggc aatatgtatg aatacatcaa
     2941 gaattattaa aaaaaaaccg atttcagcaa aacattaaaa aagcccgtgc tgcaacacgg
     3001 actcatacct catttctgag atcacaaata tattataaca agaagtgagg aatatttaaa
     3061 tggcaaaaaa agttatgggt caagacggaa aaatgtataa agttagtaaa cctttttaca
     3121 aaaaagtatg gttttgggta ttagcagtaa ttttaattat aattattggt tctgctttaa
     3181 atggtggttc agatagcaat aaagcaagtg ataatggtgg cgaaaaagta actaaatctt
     3241 caacctctgc ttcatcttct aaagaagaaa aaagcgatac tttctataag attggtgaca
     3301 ctgtaaaagt tggtgatgct gaatatacac taaacagtgt agaactaact gatgaaagaa
     3361 atcaatttga agaaaatcaa cccgcacaag tagtaaaaat tacttacact gtaaaaaacg
     3421 atggtgattc tgatctccct gtaggaacag acgtggaagt atacggacca gatgacaaga
     3481 aatcagaaac atatgccaac gaaaatacta tgggggctgt tgctccagga aaacaaatgg
     3541 atgtaactgc tcatttcacg ttaaaccaaa cgggagaaat agaaatccac ttctctcctc
     3601 tagtatcatt tgaaaaagca gctattttta aagcaactgt ataataaata aaaacacgcc
     3661 ccaccgacca aagcgagcgt gttctaaaaa aaacaaacct acataatagg cttctttata
     3721 gtgtctattg tatcaaagaa agtgagccga ttcaatcatg gcaagatttg tgaaacgtgg
     3781 aaatagctgg caatacgaaa tttcatacaa aaaagatgac ggaaaataca cgaagataag
     3841 aaaatcagga tttaagacaa aaggcgaagc aaaagatgcc gccaacgaat tagaatataa
     3901 cttgaacaaa ggccttaaag gggatcgcaa aaatctatta ttatcagatt actttgagga
     3961 ttggatgcaa ctttataaag aaggaacagt atctcctatc acttatagaa aatacgaaga
     4021 tacgttaatg aacataaaga aatatatgcc agcggtattg atttctgatt tagatagagt
     4081 tggatatcaa cgctttttaa ataagtatgc gaaagaccat gtaaaatcca ccgttattaa
     4141 gtttaataac catattagag catcgttgaa agatgccgta gaagaaggat taattccgtt
     4201 tgatccaact agaaaagcag taatcaaagg aaaagattca ttgaagccaa aagaagataa
     4261 atatttagat tatgatcaat ttaaatcttt aatgaaactc gtagaagaaa acctttctgc
     4321 acagtactct tctcctatgc tcgtgttagt tgctggtgct actggaatgc gatttgctga
     4381 acttctagga ttaacatggg aagatatcga tttcgaagat caaatcatca ctattaataa
     4441 aacatggaat tataaattaa atgaatgggg aaaaacaaaa aacgaaactt caaataggaa
     4501 aatttccatt gataaacata cgattgatct cttaaaaaag tttaaaatca atcaaaaaga
     4561 attattcgag aattttgaaa tcaaaaaccc tcataatttt gtttttttca acttaaaaaa
     4621 tggattagtt tcatcaaacg ccgtcagcaa atatttgcgc aaaaaattaa aagaattagg
     4681 gattgaaaag caatttactt tgcatggact aaggcataca catgcatcta ttttacttta
     4741 tcaaggagta aatatactta gcgtatcgaa acgtttagga catagcagtt tagaaactac
     4801 aatgtctact tatcttcata ttgttcgaga gcttgaagat caggataaag aaaaaatcaa
     4861 tactgtgttc gatagtttat ataaaaatga taactagttt ggcacatttt tggcacaaat
     4921 acaaaacaaa cccctgtacc gcaaaggata caggggttat ttatacgttc ctgactggaa
     4981 ttgaaccagc gacctatcgc ttaggaggcg attgctctat cctactgagc tacaggaaca
     5041 atttcaataa atcaattgta gcttgtttgt tttttacttg caagcttatc tgctaaaaaa
     5101 atcagcttat aagttaggca aaacgtttcc actagtcctt aacagatgat aaactagagg
     5161 tagaatgaaa taatgtaggg aggtcctttc caatgaatga taagccaaaa gaaaaagtat
     5221 acgcagaacg cttagattca tctaaaaaaa atcgggaaaa gattacgaaa gaagcaatcc
     5281 aagaccacaa aaaagaaaac cctaaaacaa aagaaaacaa aaaattcaaa tttacgaaaa
     5341 aagaggattt actttaacat tttccttcaa atgccaaatg aaaaacaaaa gggtggtgac
     5401 aaaaatattg tcatcacccg ttttttatca aaaatagtca ttaagaattg gctgttgctg
     5461 tggcaagatt gagcttaacg tttcttcata ttcttttgtc acctgtattc tttcttggaa
     5521 taccaactct tccactttac gataccctaa taatagctgc gtgatatgtt ggatacttcc
     5581 tcgaacgatt gggagttttg tttgttctac ttttgagaga tgattttttc cattttcgat
     5641 tgttacttcc acgattcctt cattccattt cgcataatga tcttcttcta tttgtagggc
     5701 aaatgcagct tgtctctttt taaatggata attttccaaa aacaaagaaa tatctacgat
     5761 cctcgccatc atataaggtg tgatcattac agaagcaaat ggattttcta atagataatt
     5821 ttgatcatta ccgccgtagc cgcatgaata ttcaaatgtt tcaaaagcac cattgtgaga
     5881 acttacgaag cgaacaaggc tgcaaaaagc atcatgatcc aaaaatcccc actccgcaat
     5941 aataaaggaa gacgttgcaa gctgataaac gatatatccc gttgcttcct cattatcatc
     6001 aaaatgcaaa gcaaactggt aattgccttt ttgcttgaat ttatacgtat accaccagtc
     6061 ttcgcgcttc agaccagctc gttggttttc cggcatctgt tcataaattc ttctgattgc
     6121 agcttttgca tcttcaaaat ccatacgctt tatttttcca gatttttttt tgataaacgg
     6181 cacatcacga ctgtttagtt gataactgat tttatcaaat gattgttcat agccatagcg
     6241 ccgatagaag ggataggaga atggcgccag ataagataag cttactttac gatcacggca
     6301 atcttcaagg atcttttcca tgatctgatt gatcccgcct tgtccccttg cttctggata
     6361 agaagcaaca tagccaatgc cggccattag gtactcttgt ccgtaaaaat tcactggaaa
     6421 aggggtcgcc atgacttgac ttgttagccg atcctcctca tcaaaaaatc cgtaattcca
     6481 agaattctcc gcaagtgtac gaaaacgttc tcgcctttca ggtgtatctg ccccattaaa
     6541 tgcataagtg gctaaatcaa acatttcctc aatcgaagat acacctagct ctcttacttt
     6601 gtttgtcatt ttgctgcccc ttcctacaaa aaagctagtg aggattcgca ggaaagatct
     6661 atcttcctat gaaaaattcc ttctagctta cttcattttt caataactaa atagtaccat
     6721 gtttcattga tttaatacgt tgcttcgatc atatctagca tttttttgaa acgtctccgt
     6781 ttaaaataca tcaagattgt tcctaaaagc atatcattca acttttgaag catgccataa
     6841 gactccattt tttctgtgta atgaacctca caggtcgaat cgtccaatgg tttgatttga
     6901 taatgaacga cgaattcatt cttcgttgtc gatgtacgaa acttataaga ctggttttca
     6961 atgacttctt cgatttttat gcgagcccgg ttattttgcg agaattgttt gacgtactcc
     7021 aaatttttca gctgttttct agttactgat ttgccggtcg ctttacgtac atcgaaaagg
     7081 acagagtcca taactttatc gtaaaaaaac gatgctggaa tatttaattt tttcgtgatt
     7141 tccattagtt atttttctcc tttgcttctt ctcttttttt ccccttcatg aagaaataga
     7201 ttcctaatcc tgttagaaaa agacctgtga ccatactata caaatcatac ctttgcgaat
     7261 gtggattcaa actatacaac acgatcaaag aaccaatact acataaaaat aaaccgtttt
     7321 ttatcatctc aaccatccta tctttttaaa ccattttcta aacagctgtt gattgaaaat
     7381 aaaggactgt tccccaaggc tgtgctttga ttagttcctt tgctttttta gccgcaactt
     7441 ccggatcttc tgcacttgtt tcaaagaaca gcttgattcc ttgtttttct ttaaatgtaa
     7501 aagtcattcc ttcttcattg tatccttcta acaattcttt gatttcatct tgttgcattg
     7561 cactggcaat tgtaatcatt tcagttcctc ctcgaaaatt cattatgagg aacgaaactt
     7621 aaagcgtccc gctcctcacg ttcatcttat tgttgttcgc ctgcggcagg gtccattttg
     7681 tttgcagaga tgacaaatgg tgcccaaatc aagaaagtca cgaccataca tactaatgtt
     7741 acgatcggtg cccgccaatc cgctcctgtt gctaagaatg acaataagaa cggcggtact
     7801 acccatgtga cttgctgcga taccggagcg actaggccaa gataagtagc tgtccatcca
     7861 attgctgttg ctactactgg agcaatcaag aatgggataa acatgattgc attcaatacg
     7921 attggcagac caaacatcac tggttcgttg atattgaaga taccaggccc aatggataat
     7981 ttagctactg ttagataatc tgcacgttta gagaaaatca agatagctat cagtaagacg
     8041 atcgttccgc ctgatccgcc aaaccatgca aaagcatcga acgatccgcg gacccacata
     8101 taagcttttc catcttcgat tgcatctaac acggctggtg taccagtttt tccgttataa
     8161 cctttttgga aaatatcaat attgattagt tgtgcttgtc cccagattcc ctctagcact
     8221 ggtgccaata catttggtcc atgaatacca aagaaccaga atacttgaac aaatactgtg
     8281 acgatcaata ctgctcccaa cccttgagat aatcctagga atggttctgc aatatatttt
     8341 tgcaccaaat caatgatcag ttgcccatca gctacacgac ctacgatata attgataata
     8401 gcaatgacgt ataaagcgat cgtcgctggt aaaatggctg caaatgcttt agatactgct
     8461 ggtggtactg aatcaggcat tttgatcgta atgttggcaa gcatcaattt acaaaaaata
     8521 atgactgaaa tagctcccat gatcataact gtaaaataag cgtttccatt caaatgatct
     8581 agttttagcc aaccccataa tccaactgac agtgtgccat ctgcaatcgt tgcaccaatc
     8641 tcagaactat tgattgcatc tgcgacattt gaaggaacat tcacatctaa tgctgctgat
     8701 aatgctggac caaaggaaat accttgaatc aaggtagcta aaccaacgat ccccccagct
     8761 agatcattta ctccataagc tcgggcaaga ttataccccc aagaaaaggc aaagatcaat
     8821 ccggcgattg ctagtgtacc gttccagaca aaaccattga ttccgatgat gacattcaat
     8881 acggcaaaga ttcctttgtc tgctgctaaa ctgtcagcat aggtactgtt aaactgttgc
     8941 ggtaaatcac gaataattgc attgatcatt acagcgactg atcccgccat tgttgcgggc
     9001 agtgtgccga taaaagcatc acgcaaagca actaaatgtt tttgcgctcc gatttttgcg
     9061 gcaaccggca ggatgtattt ctccatccaa cttgatagtc cgttcatttt ttacttcctc
     9121 ctataagttt tttatataaa gagagttctc cttataacaa aataaaaaat ccgttcaaaa
     9181 atttttcttc ttccgttcaa aaaagaagtt gtatttattc gctgtatacg cgacgataaa
     9241 gttcgatgat ttcttttgct aaatcagtaa acgcaataga tgtcattaag tgatcttgac
     9301 tgtgaacagt caataatgtc acttgcatat gatttccttg tgcttcttgt gtcaacatgt
     9361 ctgtttgtgc atgatgcgct tgtataagtg attcttctgc atcagcgatt ttcctatccg
     9421 ctaactcaaa atcaccgatt ttagcagccg caatcgcttc cattgcatcg ctctttgcat
     9481 taccgccaaa catgattaac cccatgatgg cttctagatt ttgttgatct tccacgttgt
     9541 tataccccca actgcatact tgatttattt cattagattt tctgcttgtg caagaacttt
     9601 ttctccgttc atcatgccat agtcttgcat attgatgaca tctaatggaa tacctttagg
     9661 cgcaagtttt tgttcaaatt gagctttcat gaaacgtact tgaggaccta ataataatac
     9721 atcgacattc ttagattcta aattattatc tgcatctgag gcagagaccg caaaaatatc
     9781 ggcttccatc cctttttctt ctgctgcttt ttgcattttt gtgaccaata aactcgtact
     9841 catccctgct gaacaaacta acatgattgt tttttttgcc atttttaaca ctccttttat
     9901 ttttttacac ttttatataa cgcaagaagc atgccaataa aaaaaagagc tgaaatagcg
     9961 ttttcatgct ttttagctct tttttatagt gcgcacacag atgtttagtg tgtaaacagt
    10021 atgattagtg tgttcatttt tttattttat tttcaagaaa catttgtgta agaaatgcga
    10081 tatcatcttc tggaattttt acctgatatt ttcgttctag tgccatcaag tttgcccgaa
    10141 cgatatccat ttccaaacga taaatttttg agaaaataga cagtttctca aattgccgat
    10201 ggctttcttg tttgatcaat ccgtctaaca tgaaggctaa atggataacg attccagtat
    10261 ctactccagg ttccacgata atcgacaaat cggtctggat ctgctgaact gtcttttgca
    10321 atgaacggat cagttcatca atagaaaaga catcgcttaa tgatccagca agtgaatcga
    10381 caattttagc tgtcgggatc tcatcatcag ctatacgctt taaaatattt agtttttcat
    10441 catcaaaaac gtcataggct gaaaaaaatg ggatattttg ataatcaaca tcaactgttc
    10501 ccgcaattgc tttgatctca tattcttcca ataaggcatc gatgtgtttt ttgaatgatt
    10561 cacgttctaa aaactgcatc tggatcagtt ctaccttatt ttgattaatc actggcataa
    10621 tacgctgata taatttggca gctactcctt caccagtaaa gcatgtcacg attacggctt
    10681 ttttacgctg taaagtttca gacttttccg ctttgaactg atcacgtacg atcgattcaa
    10741 aggaaagctg gatattttga taaatatctt ctaagcttct tccaacactt gccatccgta
    10801 tcgcttctat cacaatcatg gtacttgtca tcgtgatagc tttcgtccga atgccagtct
    10861 cttcataaat caaatcactg aaggtgttta atgatcccat atctgttaac aagagtaggc
    10921 cattcgtcaa atgctcttga tagtttttga catattgtaa cacttcttca tacattgttt
    10981 gaacttccat aaccagtggc atattaaaag ctttccctac ttttgttcct aatagttctt
    11041 gtgccatctc caacatgctt gaagcagtct gtctgccgtg catcaatatg agaacatcta
    11101 ctttgttttc tttaacaggc tcactttctc ctagattgat agaaagaaac atactaataa
    11161 agccgatttc atcaaaagga atctcaactt gttcttcttc ttcaatgatc gttgaaagat
    11221 cgattgctac ctggaattcc ctcttaaaat ttttccgtac gttattcaaa tctgggtgga
    11281 cgatcatatg accttctctc acacgatcca atgtactttg cagatgcaaa gcaaaagcaa
    11341 aacgagcttt ttcattataa atacggtcta accgtttttc agccacatca tacaattgat
    11401 tggttaaccg ccagatttca tctggcaaaa gatctttggg aatcgaactt ttagtcaatt
    11461 ctttgacata tgtctggaaa taagcatcca catcttttga aatgagggtc tctagatcaa
    11521 tgttctccac accggtttcg gaaagagaag tgactttttc ctcaatatcg ttatagacct
    11581 gcatgtttcg ttctggatct tgtgaccaga caacatcagc aaatcctggt tcaaatgtca
    11641 aatactgact tttgctgtcc atgaatcggt cgagacgttc cggtatttcc ttgattttca
    11701 gtaatccttt ttgtacttga agggaaagtt cttcttttcg aatgattagc tttttctcat
    11761 gatgagtacg gtaatgtaaa aaagattttg cacagactag tttcaagtct cgtttcactt
    11821 gaccgatatt tccttccgca tcataaagca tgaaggcaag aatcgcttct ttttcgatat
    11881 cgatacgttg attcaaacga ttcgcttctt gtttgataaa aagagagatg atttcataac
    11941 gctcatccag tgaacgtgaa gcaagattcg gcaaggtgat tgccatagga atccgtcgat
    12001 tgaacgtaga taagaaactt tctgaagatt cagtcgtcgc cccaatgatc tgaacagatg
    12061 cttcatgtac ttgtgcactt tctccaagcg gacggtaaat acctttatca atgaaagtaa
    12121 acagcatttc ctgcccttcc ggcggtaaac ggtggatctc atctaaaaac aatataccgc
    12181 cgtctgcttt ggctattaga ccgggactat cttgagctgc tcctgtgtaa gccccttttt
    12241 tgatcccaaa gatgtgtcca aagagcagtt gcggattttg agcataatcc gcacaattga
    12301 aagaaacaaa tggcgcatct gcagaaagca tctctgaatc gattgcaaaa tgatacatac
    12361 attcagcaaa catcgacttc cctgtaccag tttctccaaa aataatcgta tgcaaccccc
    12421 gcggtggata aagaatcgca gcttttgcct gctgtatgct gacttttaaa gaatcatttt
    12481 ctccaacgag tgtttcaaaa gtcacttgcg tagaagagtc gacatgcact tcatcagatt
    12541 ttgacttttc cgttggcaaa gagtaaacga ctggtcggcc agcggttttt acaatatgat
    12601 gggccttgta tagttcactt aaatatcggc ttgcattgct tcgatcgata gttaagcgct
    12661 cagctacatc acttgctgtc aatccttgtt ggttttctgt caatagctgc aagatctctt
    12721 cttgacgttc tttcacataa cccctcctct ggcaaccaat tttgttcccg ttttcataat
    12781 catagcataa aaaggcgctt atttgcgcct tgctccttta tttctctctt tttttgattt
    12841 atttttaact ttttttctta ttttttcttt gttatattct gggttctgct cctttccaga
    12901 aaaagttttc gcatactttt tatttactgc aggagctgca tcttctttgg ttggctgctc
    12961 agtttgcagc ttacctccgt ataaaaaaat ctcttcaagt gttatatttg atggacgtaa
    13021 aagccgtttt aaatctctta gattattatc ttgtacgagt gtaattacta ttccttcatt
    13081 acccattcga ccagttcttc ccgaacgatg caaataagct tcttcactta acggaacttc
    13141 tgcattcact acataaggaa gacctgtaat atctaaacct ctagccgcca catctgtggt
    13201 caaaagtgct ctgaccattt tctttttgaa ttgttctagc gctgcttttc ggagtagctt
    13261 gttctgatca gaggccagac ttcctaccgg tacacctcta tacagcaatt tttcttccat
    13321 tacgcctaat tcagtcagtt gattaaagaa aatcagacca tgaaaatctt ctatatgcgt
    13381 gagacgtctc aagtagtcat ctttctttcg tatcggtaca cgtaaaaagt aatgtctcag
    13441 tccttttcga gaatcgtcct ctgctgtcac gtcaattgtc tcaaacgttt tcccagtgat
    13501 tttttcaatg ctttcaaggg aacgatctgc tgtcgctgaa aaaaaagcta gctgatactc
    13561 tgttggagct tgatgaagaa tttgatcaat gatttggctg ttcccagcgt caaatagctg
    13621 gtctgcttca tcaaatacca ttgttttcac ttgatgtgct tttatttttt ttgctttcat
    13681 caattccaat attcttcctg gtgtaccaat caagatttct ggtttttcct tcaaaccctc
    13741 aatctgacgt ttgacgttgg ctccgcccac caaagattgg actttcaact ctttgtcttt
    13801 tccccattca cgtgcaacat ctgctacttg aatagctagt tcttgagaag aagcaaaaat
    13861 gaccaacgca cttgcttcac ctggttccac gtttagtagt agaggccaaa gataagccag
    13921 tgttttacct gaacctgtag gagaaaccgc tactatactt tgtttattac ttagtggctg
    13981 aaaaactgct cgttgaataa gagaaggtga gataaaccct ttatcctcat attttttctg
    14041 ccaattttcg ggaaatactt gtacaaattc gttcattaaa aatcttcctc attatctgca
    14101 tcgaatttga tgccgccatt ttttcttaaa tcataaatca cttggttcac atttctagct
    14161 agctcgatcc actcttcata caacaatccc caagctggat ctttcggatg agccatgaca
    14221 ttggcaaaat cctctgcttc atctgccatt ggattttctg cagctgttac cgccaaatca
    14281 atgatttctt tatgcgcgcg atcatgaaat tgtgcttgtt caattgcatt gactccattc
    14341 atcactagcg ttcctgagtc aaaataaatc tctgacggta aataagaatc accgatttta
    14401 cctggctgga tcgatacatc aaaattctca taacgtaaga tcccccatcc aagaccatct
    14461 acaccagtag aaatctttct tgggaaataa tggacttctt ttggcattcc aaaccaagca
    14521 acagctgcat atacaaggta aacacctaaa tccatcaatg caccacctga gaaatgagtc
    14581 gagaagatat tcggttcttc tccatctaat acttggtcat agcgcgaaga atatttcata
    14641 tagctgaaat ttgcaccgat tatctcgtct tttaatggta agtaatcggc aatcttttta
    14701 aaacctgatt catggatatt tcttgctgct tcaaaaaaat acacattgtg ttcatttgcc
    14761 aaatggatga tttcatccat ttcttttggc gtcgaaaaag ctggcttttc aactatcaca
    14821 ttttttcctg ccaaaattgc ttgcttagct tgactaaagt gaagactatt cggagaagca
    14881 atataaatgg tgtccatatg agtaatattg aaaaaagtct tcaaatctgt tgcgaattcg
    14941 atatcccctt cataatgaga accaaattcc tgtgcttttt ccaaatgtct agaatatacc
    15001 gctgtcaatt catatttttt tgtgcttaaa gctgcttgga caaattgatg agtaatccaa
    15061 tttgttccga taatacctaa gttgatcatt attttacctt ctttctattg tataggatct
    15121 tcaaaaggga tatctacatc aaatggaatg gcctgcttga cagttacctc atctgccgat
    15181 acttgacaat tataggcgag gatttgaact ccgctttgct gcgcatgtcg aaccatatca
    15241 gctagtgctg gttgcatttc ttcatggatc gttgccagat gaagatgttc gaactgagca
    15301 ataaacaaga cataagcggc ataaccatct tgtgcggcat acgttaattc tcctatatgt
    15361 ttcaatcctc tgagtgtggg cgcatcagga aaagcaccaa tcgctttatt ttcaagtgtc
    15421 atacctttga cttcaacaaa tgctttttgt ccgaccaccg tctctaaata aatatcaaat
    15481 ttggagtgaa gataagttac ttcacgcttg tataccgtaa atggaccagt taatcctggt
    15541 aaaaggatcg tgccgtctaa aataccatca attgccagcc gattaggcaa ttgactatcg
    15601 atattaaacc agtcaccctt cttttttaca gcaatcagat cataggcggt tttccgttta
    15661 ggtccaggag caaatacaat agccacttca gcgcctggta tcaggacctc ttttcctcta
    15721 cctgtatttt tgacatgcgc aataattatt tctccgtctt ttttcataca atgtgctata
    15781 aaccgattcg ggcggtcaat aaaaaaagct atttccactt gctgatactt caaattatgt
    15841 cacctttctt cctactatgt atcctatcat aatttgtaga aaaacagtaa aaaaaccagt
    15901 cgaaagtctt agagaaattt tagcttttat tcggtacaat gaaataaaga agaaagaata
    15961 tgtctatgcg attattttct cataaaggag tgatttggtg ataaaaaaaa tgatctattt
    16021 tcttggttca ctcattaccg ttctctcaag ttttatttac ttgaaaaaga aaaaacaagc
    16081 ggaaaagtca gaaggactct caaagtatca aggtacatgg ttctttagtg atagccagca
    16141 aaaacaacaa ttacagatta catctgatta cacgtttttg atcaacggtc agtctcttgg
    16201 cacatctgtg gtagaaatag atgaatatcg tttagtcgta cgtgatcagt atggttttta
    16261 tcttatcttt tcttatcccg aacaaactct ttatgacgaa tctgcagaca cttcatataa
    16321 gttgttatct gaaaaataga tccctcccaa tgtatatata tatcctttat aaacgaaaga
    16381 atgagtcttc tctatcatct ttcgtttttt gttgtaaaaa cgtctaaaaa tcctttgttt
    16441 tttatttaga aaaatagtca attaacgttt tttttgttac acttactaat gatggttttt
    16501 taccatgaaa ggatgatcga atatgacacc aaatcgagaa gattatttga aaatcatttt
    16561 agaactaggt ggagatacaa cgaaagtcaa caataaacaa atcgtatcta gtctagatgt
    16621 ctcagctgca tctgtcagtg aaatgatttc taaacttgtg aaagaagagc ttgtagaaca
    16681 ttccccttat caaggtgtac aattgactgc aagcggactg caaaaagcta gcagtctgat
    16741 tcgcaaacat cgcttatggg aagttttttt agttgaacat ttagactata gctggaatga
    16801 agtccatgat gatgctgaag tattggaaca tgtgacttcg gaacatcttg cagatcattt
    16861 agaaaactat ttgaatcatc ctgaacattg tcctcatgga ggatcgattc ctaaaaaaga
    16921 ggaagttgtc catgaagaac gccgacaaac attggagtcc tatcctgtcg gtacaaaagt
    16981 gcgtatcgca cgagtgcttg atgaaaaaga attgttggat tacttagtca ctattgacct
    17041 gaatatcaac gaagaatatg agatcgttga catcgcagct tatgaaggac cgatcactat
    17101 ccaaaatgat agaaagaaaa tccccgtcag ctttaaggcg gccagcacga tttttgtcga
    17161 taaaatataa aggagtgtat ccacatgtct aatgaaaaaa atgtattgtt tacgatattc
    17221 ggcggtacag gtgacctagc ccagcgtaaa ttgtacccgt ctttgttccg cctttacaga
    17281 aaaggaaatt taggcgagca ttttgctgta atcggaaccg ctcgccgtcc ctggagcgat
    17341 gagcactacc gtgaagttgt caaagaaaca atccgtgcat tgaatccttc agatgaagaa
    17401 gcaactacct ttgcaagcca tttttactat caatcccatg atgtaaatga ttcaacgcat
    17461 tatcagacat taaaagaatt gtctgaccga ttagatggac actatcaatt aaacggtaac
    17521 cgtgtctatt atttggctat ggcacctcaa ttttttggaa cgatcgtttc tcatttgaaa
    17581 tcacaaaata ttatgacaaa aaatggcttc aatcgtttga tcatagaaaa accgttcggt
    17641 tctgattacc agtctgcttt tgaattgaac cagcaaatca gagaagtatt cccagaacaa
    17701 gatattttca ggattgatca ttatttagga aaagaaatga tccaaaacat ctcagctatc
    17761 cgttttgcca ataatatttt tgaggctcaa tggaacaatc gctatatcga caatatccaa
    17821 attacttttg gcgaaaacct cggtgtagaa gatcgcgggg gctactacga tcatagtggc
    17881 gcacttaaag acatggtgca aaatcatatt ttacaggttg tagcattact tgcaatggaa
    17941 ccgccagtag cattttccga aaaagaaatc cgtacagaaa agatcaaagc attgaaagct
    18001 atccgcattt ataacgaaga agaagtgtta gaaaacttcg ttcgcgggca atatgctcaa
    18061 ggtgaattgg atggtgtaca attcaagggc tatcgcgaag aagacaaagt ggatgctcaa
    18121 tcagagactg aaacattcgt cgcaggcaaa ttcactatcg ataacttccg ttggtcaggt
    18181 gttcctttct atgtacgtac aggcaaacgt ttgactgaaa aagggactcg gatcaacatc
    18241 gtattcaaac aagttcctgt taatgtattc aaaacatctg tcgatgaacc atgtgacgat
    18301 acgacacttc cacctaatgt tctaacgatc tatattcagc caactgaagg attttcttta
    18361 tccttgaatg ggaaagaagt agggcaagga tttgaaacgg aaccaatcaa attggaattt
    18421 agaaatagtg cagaaatggt tgaaaatagc ccagaagctt acgaaaaatt actattagat
    18481 gcgttgaatg gtgatggaac gaacttctct cattgggaag aagtcgctca atcttggcat
    18541 atcgtggatg tcattcgaaa aacttgggac caaacacaac cggattttcc caactacaaa
    18601 gctggatcaa tgggacctaa agcagctttc gaactacttg aaaaagacgg attcgaatgg
    18661 atctggcaac cagataactg gtatcgtgaa cgtggaaaat taaacgattg ataacaaaag
    18721 ggggtgtgac aaagaacatg tcacaccccc ttttcccttt tacttttctt cgaatccttc
    18781 agctacagct tcaggataga agtcttcaac gatttttgca caacgaccgc atagatgagg
    18841 aagtttttca tctactccta catctttacg aacttggcga cagcgatcgc aagtttcccc
    18901 gtctgctttt tccactgtaa tagcaacatc atcaaatacc atagcgttat ctggcacttg
    18961 ttcatctgct gccataactt caaagtagtc tggtgaaacg atcaataatt gtgcaatatc
    19021 tgcatccaaa gcttttaaca tttcacgaac ttgttgtttt ggataaacag ttagttttgc
    19081 ttccaaagat ttaccaatca atttgctgtt tcttgcttct tccaatgctt ttaagacatt
    19141 atcacggaag tccatgaaag cagtccaggt atccatcaat tcttcttggt ttgcaaactc
    19201 ttcataacca ggaaactcgc ttaactgaac gtactcctct tcttctttca ggaatgacca
    19261 gatttcttct gctgtatgcg gaatgatagg agtcaataat tttgtcaaag ctacagctgt
    19321 ttgatagaaa acagtttgca tgcaacgacg ttgataatca tcttctgctt caatataaac
    19381 tacatcttta gcaaaatcca ggtagaatga cgatagatca accgtcaaga agttcataac
    19441 tgtacggtaa atatgcatga agttatattt gtcgtaccct tcttctcgga tttctttgat
    19501 tacttggttc aatcgaacgg tcatatattt gtctacagaa cgtaaatcat tgtacgaaac
    19561 agtatctttt ttaggatcga aatcttctgt attcgctaat aagaaacgca tcgtatttct
    19621 gattttacga tatacttctg ccacttgact taagatatcc atagaaacac gaacatctgc
    19681 ttcataatct acactagata cccataagcg aaggatatct gcaccaaatt gtttgatcac
    19741 tttttctggt gcaatgatgt ttcctaaaga tttactcatc ttacggcctt caccatctaa
    19801 agcaaatcct tgagaaataa ctgatttgta tggtgctaca ccattgatag ccacactagt
    19861 cgtgatactt gagttgaacc agccacgata ttggtctgat ccttctaaat acatatctgc
    19921 tgggaatgat aattctggtc gctgacgtaa aacagcttca tgagaagaac cagaatcaaa
    19981 ccagacatcc atgatatctt tttcttttgt aaattcgcca ttaggagaac ctgggtgggt
    20041 aaatccttca ggaagaagtt ctttcgcttc tttttcaaac cagataattg atccatgttc
    20101 agcaaataat tttgccacat gttcgattgt ttctggtgtg atgattgctt ctccattttc
    20161 agcatagaaa atcggaagtg gtactcccca tgcacgctga cgggaaatta cccaatcgcc
    20221 gcggtcacgg atcatattat acaaacgtgt tttaccccat gggataaccc actctacttt
    20281 ttctacttca tccaaaatat tctgacggaa tttatcgata gatgcaaacc attgtggagt
    20341 tgcccgatag atcacaggct ttttcgtccg ccaatcgtga ggataactat gagtaaagaa
    20401 atctagcttc agcaaagctc ctttttcttt taatagatca gtgatcatag gatttgcttt
    20461 gtcataaaag ataccttcaa atccaggtgc ttcttctgta aacaatcctt ttgagtctac
    20521 aggtgacact acagatagtt tatatttgct accagcgata tagtcatctt ccccatgtcc
    20581 tggagcagta tggactaatc cagtaccagc gtctaaagta acatgatcgc ctaaaatcac
    20641 aagtgattca cgttcataga atggatgact tgcagtcata tattccattt cttgtccagc
    20701 aaattctttt agaactgtta cattttccca accgatttct gattggactg tttctagcaa
    20761 atctttcgct acgacaaact tacggccatc ggcttccacc aatacatacg taaattttgg
    20821 atttacagca ataccttggt ttgctggcaa tgtccatggt gttgtcgtcc aaatgacaaa
    20881 agctgtatct tcatcaagaa tatctttgcc gtctttgaca ttgaaagcta caaaaataga
    20941 tggagatttt acatctttat attcaatttc agcttccgct aaagaagact cacttgacgg
    21001 agaccagtaa attggtttca atcctttgta aatatagctt ttttcagcca ttttaccaaa
    21061 tacgcgtact tgtgcagctt cataagaagg atctaatgta acataaggat gttcccaatc
    21121 tcctgcaact cctaggcgtt tgaaatctgc tcgttgctta tctacttggg aaagtgcata
    21181 ttcacgacat ttttccaagt attctgccat ggacatttct ttacgtttca cgcctttatt
    21241 agccaatact tgttcaatcg gcaatccatg tgtatcccat cctggaacat atggtgcacg
    21301 atagccagac attgattttg aacgaatgat aatgtcttta ctgattttat tcaatgaatg
    21361 tcctaaatgg atattaccat tggcatatgg aggtccatca tgaagaacaa agctaggttt
    21421 tccttcgttc aactcttgtc ttttttggta gattcgattt tcttcccatt ctttttgcca
    21481 ctcgccttct cggtttggca gattaccacg catagggaat tttgtttttc ctaattgcaa
    21541 ggtttctttc attttcattc aaccatacac tcctttattt gttttccgga cacaaaaaag
    21601 catgttcagc cgcaagggac gaacatgccg tggtaccacc caaatttagt tgcatctatc
    21661 tagtgcaaac tctctgtgac caataacgag gtcagccgct gcttcttact ctaatttcgg
    21721 aaaagcaggt ctcaagtaga ggatctttca ccatgcagtg tcttaccgaa cttccactct
    21781 catcggctcg ctttaagaat aacaaagtgc ttttctgttc tactcgtttt cattttcacc
    21841 aggcacgatc gagatatcaa tagcctgtgt atcaaatgcc gtcataggtg cttctatgac
    21901 tcctgtgtct gagtttacat cagtatcatt ttcattgtca agctgttttg ctaaaacttc
    21961 tttgatcact tcatggctgt cagtcacgta gctggagaat ggttgtaaaa tttcatccca
    22021 ttccggactt ttcacttgtt ctaattgaga ctcaagcatc aagctgatac gttgatggaa
    22081 tactcgtgtt tttttcttaa gatcttcagt ttctgtcgca agctgtcttg ctttttctgt
    22141 tgcatctgtc aagatttttc ttgctttttc ttctgcatca gttgttaatt gatgtgcacg
    22201 tttttcagcg ttcgcaacta actcatctgc tttgttttgt gcagaagtaa cgatcacttc
    22261 ggattccttg cttgcacttg tttttacttt atcagccgta tcttgagcta cgatgattga
    22321 ttggttcaaa gcatctttta attcattgaa gtactcaagt ttttcttcag aatgtttgac
    22381 tgctttttct aattctcgat ttctttgagt caattcctca tagtcacgaa caactaaatc
    22441 taagaaatca tctacttcgt cttgattata tccccgcatt tttgtcggga atgtcttatt
    22501 ttggatatct aatggagtta aagccatgag taaaccacct ttttatttta tttacgtaat
    22561 acaccgaaca gtaccctgta cttttctttt ttcgtcttcc cctcaagttc ttggatctgg
    22621 actctgccat aacctctgac tgaaataata tctaatagtt caagtacaaa atcaggtctt
    22681 gtattttctg tccagttcac ttttacttta ccagcttcga tcagctgctt ggaccgctgt
    22741 ctggaaatat tataaatctc agagatcaca ctgtctagtc gcatggaact aactgttcct
    22801 ctttcttgtg tccagctatc tttcggcata atcatttctg tgtatttgat tggttccaag
    22861 cgtacagcaa cctttccaat ctttgttact tgtgcagcaa caaaatgatc cacctcattt
    22921 gcaataaata cttgccagcg atcaccgtcc gagatgatat cgccaaagta agagcgtttg
    22981 atccccgttc ccactaaagt tccaaggatt ttcccatgac ttaggctggc aaatttgcta
    23041 ggataatgga tttcatacaa tgctgtttca aaatcttcct ctacaggttc gtaataatcg
    23101 gggaaaatca aacatctttt tctttctgcc tgttcatatc cgccataaaa catgaaacgc
    23161 aaatcactgc tttgtcgaat cagtgtttct aaaatatagg attgtcttgg gtcaagaaat
    23221 tcggtcagat agggtgcata ttgtccttga acctgttcaa tccaatcgcc taccgaatcg
    23281 ataaatgtac gttcatctgc ccgaaagtgc tggtatacat ttgcatccaa aattttcccc
    23341 tcctatctat tctgagaata aagattttgt tgcttcaatc aataaactaa atggacagtt
    23401 atccatataa cgatctgtgc taaaccttgt acggctaagt tcaagatcag gattgcccct
    23461 aaaattgtga aatccaaggg tccaatcctc aaaggcagac gatcgaacaa actgatatac
    23521 ggttcgcaga tcttagctaa taatcgtcct agccctgatt gatacccgcc tggaaaccaa
    23581 gagagcaatg catataccat caagataatg ctatagaaat aggctgcccg ttgaagtaaa
    23641 tgaagtaata gtgcaatagt ataaatcgta gttcctcctc ttacagatca aacaaattcg
    23701 catctgcaaa agattgagcg gttgaactgt caatctccat cccagtcggt gtacaaagaa
    23761 aaatctcatc tccaacacgt ttgatatctc catctagtgc ataaactgtt cctgttagaa
    23821 aatcaacgat tcttctcgct tgtttttctt ctactaaatg aaaattcact aaggttgctt
    23881 ctccagcaat gattcgttta gcaatcgcca tagcttcaga ataagctctt ggttccatta
    23941 cagtgatttt tccagcaaga tttgctttag gttgtgtaga ggttcttgaa gctgttcttt
    24001 ctttcgctac agtttttgta ggtgattgat gtagttcaat tacttttttc ttttcagccg
    24061 gctgaatact ttcatgcgtt acaggacgtg aagtcgccgt tttttgtttt tcatgagtat
    24121 tcgcagcaga tacagaatga gttgattgat tctgtgttgt atttttttta gttggctgta
    24181 cagccttttt tgttgtttca ggataatctt ggtattcgta ctcttcctca tcagctaatc
    24241 cgaaaaaatt agcaattgct cctctgttta aaagcggcat ttttgttcct cctttattcg
    24301 tctttgaata gcgctgttcc tacacggata aatgttgcac cttcttcaat cgcaatttga
    24361 aagtcttgac tcatccccat acttaattca ctacatggtg catgggcata accttttgct
    24421 tgaacaagat cacgcaattc tttcagcgta ccaaacactt tatggatttg ctcatcagaa
    24481 gcttctttag gcgccatagt catcaaccca acaaccttga tttttgtgca ggcagctaaa
    24541 gattccacaa acggtaaaag ctcatctggt gaaattccat gttttgattc ctcaccagaa
    24601 acatttactt caataaaaca ggataattct ttctctaacc gcttctggat ttcttctgct
    24661 aatcttaaac tgtccaacgc atgaaagtaa tcaatttcat ttacaatcaa ttttaccttt
    24721 ctgcgctgta aattaccaat taaatgccac tttatttcag gaaaatcaaa taaatcttgt
    24781 ttcttttcta ataatttatc tactcggttt tctgcacaat tcataacgcc agctctaacc
    24841 aattcttcag cttgagcgga ttcaacagat tttgttacag ctactaatgt aacttctttc
    24901 ggatcacgat gaacaagagc acacgaatcc tgaatttctt gcttgatttt ctgcaagttg
    24961 tcagcaatca tgtgctcttc ctctccttta ttttttacga cggaaaaacg gtggcgtatt
    25021 taattcatca tcgccatgag attttgtttc ttcgcggttg aatgtatcaa attctttttt
    25081 ttcgatattg tcaaaattgg aatcatcaac tctaggacga acattttgtt cacgtctgat
    25141 atcccaatcg ccaaaactgt tttcttcttc tgaagaagtt ggtttagctt gatccatatc
    25201 taatacagtc ttttgagcag gtgattgcat ttgtgcttgt ctagctggtc ggctagactt
    25261 gcgttccttt tttgattcat cgatacctgt tgcgatgacc gtcacacgga tttcatcgcc
    25321 catttcttca ttgatagatg tacctagaat gatatttaca tcgccagttg ctgcatttgc
    25381 tacgatatct gaagcatctt gtgcttcgaa caatgtcata tccaaaccgc ctgtgatgtt
    25441 aagaagtact tgttcagctc catcaataga tgtttcaagc aatggagagg agattgcttt
    25501 tttcgttgct tctactacgc gatcttctcc actagccaca ccgatcccca tcaatgctgt
    25561 accttggttt tccatcactg ttttcacgtc agcaaagtca aggttaacgt aacctggcgc
    25621 tgtgatcaaa tcagagatac cttgtacacc ttgtcgtaaa acattatctg cttcacggaa
    25681 agcttcaagc atcggtgtct ttttatctac aacttctaat aaacggttat ttgagataat
    25741 taataatgta tccacatttt ctttcaaacg agcgatacct tctgcagcaa aacggccacg
    25801 tttcggtcct tcaaaagtga atggacgtgt cacgacacca acagtcaatg cgcccaattc
    25861 tttcgcgata cctgcaacga ttggtgcagc acctgtaccg gttcctccac ccattcctgc
    25921 agtgatgaaa atcatatctg caccgtctaa agcttcgcgt aaggattgtt cactttcttc
    25981 tgccgctttt tgtccaactt ctggctgaga accagcacct aaaccacgag tatatttggg
    26041 gcctaattgg ataactgttt cagcttttga attttttaat gcttgcacgt ctgtgttggc
    26101 tgtaatgaat tcaacacctt taacgttttc ttcaatcatt cggtttacag catttccacc
    26161 gccaccaccg actccgatga ctttgattac tgcgccgtca ttgatattat tatcaattga
    26221 gaattccata tcttattcct cccaggatga attaatcaaa aatatttgta aagaaaccct
    26281 tgattttatt ttttacattt tctccggact cttttggttc cggctcatcg tagattgttt
    26341 cttcaggtgc ttcatagctc tcatatgtgt ttgttgtttc ttgttcaact accatttgac
    26401 gagctgctga ggtttcaccc gtaacagcaa tttttgccaa ttgatacact tcactcaagt
    26461 ttgctgaata atccacgata cttattacat ttgtaaatac cgggtttctc agccccatgt
    26521 gatttggaac atacaatttt acatttacgc cgaagatttc ttgtgccaag tccacaacac
    26581 caggaagact agcagctccg cctgtcaata cgacgccacc tggcaactct aatgcttcga
    26641 tttggtccaa tgcatctttt gctttgttga aaatctgttc cattcgagct gaaataattt
    26701 ctgacaagta gcgttcatcg actttcactg gttctgactg accaatcaca tctactggaa
    26761 attcttcatc tggtgatgtc cgttctgggt atgcatcccc gtagtttatt ttcaacgctt
    26821 ctgcattgtt aaatgacgta tttaatacaa tagagatatc tttagtgaca aattcgccac
    26881 cttcttggtc aagattggta aacttcaatt gcttatcatg cataacagcc gttgttgttt
    26941 ggccgccacc catatcaatg acgatcgtac caaaatcttt ttctccgtca gaaagaattg
    27001 attcagtcag cgctaaagga gtaatcacca tttcgttgac gattaatccg gcattttcca
    27061 cgcatttacg tatgttatgg atgatcgttt taggtcctgt aaacaacaga ccgtacattt
    27121 ctaatcttac gccgatcatt ccacgaggat ctttgattcc ctcgaaccca tcgacagtaa
    27181 aatcttgtgg caatattgac acgatttgac gttcaggagg tattgaacga acaagggcag
    27241 ctgaagccac atttctgaca tcttcatcgg tgatttcctt tgaatctccg ttaactgcaa
    27301 tcattccctg gcaattttct acttcaagca tgtttgctgg caaaccgaca cttacgcctt
    27361 tgatctggat acctgctttt tcttctgctt gtcgtactgc tcgttgtatc gcttggaccg
    27421 ttttatcgat atcaacgata atgcctcggt taatcccttc tgattttgcg tttcctactc
    27481 caataatatt catttggctg tcgatatatt cagccacgac aactttaaca gatgtcgttc
    27541 caatatcaag gcctacatac attcctgttt ttgccatgaa tgggattccc tcctacttac
    27601 tattccatat acaagcgaac aactagcgtc cgttttaaaa tatacttatt aatagatata
    27661 ttcactgctt ccaattctac cataaattac tggtttttag aaagtacatt cttacttttt
    27721 aaagttgttt tatcaatttt catttaaact tgacggagtt gtacttggat tatcttctat
    27781 ttgacttgtt tcacttgaat catttgaatc agatgatccg tttgtgctag acgatccagg
    27841 tgtttgtgct ttttgcgttt ctgcctcttc acttgattcg tttgtttgat ccgcattttc
    27901 ttcactttca gttgtttctt ccgattggcc cgattcttcc gtttcttgag tgctaccgta
    27961 aggatgcgag aagataccaa cttccatgtc gatcacacct ttttcatcca tatctttggc
    28021 tacttgcgaa taatatttca tttggttcgc aagattattg atatttacaa taacttgatt
    28081 gccgtcattc atattcaatt ggatcagatt tttattgctt gctcttggcg tgtacttgat
    28141 ttcagaaatt gctttttgta attctgatga taactgattg tattgctttg ttaattcttt
    28201 gatttttgca gagtctttga actcttccaa gatagggaga ttttttgtag gatttgctac
    28261 tttttcatct aatactgttc cattttcaat cactgggtag tattgattgt tttttgcgat
    28321 caaagcaatc tctttatatt ctgttacatc caaatcgaat tcattcatcc ctttgaaatg
    28381 tatatttgct gtttcgattc ttggctgtgc ttttttaagg cgatcgatat aagtagatcg
    28441 atgaaaatac tgtccccaaa cattttctcc taatgacaat tttgtatcag agatgatttc
    28501 ttggctgttg actgtcttat tgcctgatac tgcaactgct tgtaatttgc tataaggaga
    28561 aacataatag atcaaaaaaa tcagcggtat acccaataca gtgatgatca aagctaaccg
    28621 acgaaatagt actttgtgcc gttgactttt taaattgggc agccggttca aaaaagaacc
    28681 gttatatggt ccaccgtttt tcttttgctt gatctcttca aaaaattcga tttttttctc
    28741 ggactggctt tcttcttgct gttcctcttg aaccgttttt tcttcttcag aatctgaaag
    28801 gggtgtatct aatgttatgt cttctttttt tggctcttgg tttttcatct cttgttctgc
    28861 cagatatttt cggttagcct tttgccaagg agtcaaattg ttttcatcag aagacggatg
    28921 agacaatttt tttggttctt ttttcttact cactaagacc accgccttta ttttttgatt
    28981 atttgtttta ctaagtcata aagacgtttt gaagcatcag ggattccttg ttctttagaa
    29041 gctcggcaca tttgcttttg caattcttca tcacccatga tttcgttgac tgtctgactt
    29101 agtgattcac ctgttagttc attatctgca atcatttttg ctgctcctgc gtgaacaaga
    29161 ctcattgcat ttttagtctg atgatcattc gtaacatatg ggctgggaac caacactgcc
    29221 ggtaacccca gagctgtgaa ttctgcgatc gaagttgcac cagcacgccc caccagcaga
    29281 tcactggaag ccatgacctc tgccatattt ttgatataag gctggacact aatattttgt
    29341 atttcaggat ttattttatt taggatctct tcataatatc tatctcctga agcatacaaa
    29401 acttggtaag aagaaggaat atattcactt aaaaaaactg atactgcttg attgatttta
    29461 agtgctcctt gactaccgcc aaaaatcaag actgttttct tttctggatc caaatcaaat
    29521 gttttcaaaa tatctgattt tttagtatct gctacttctt gtgctcgagg attacctaca
    29581 agaactgctt tgttttcagg aaaaaaggaa gccgcatctt taaatgaaag agcgatccga
    29641 tccacatatc ggcttaaaaa tttattggta acacctggta cactgttttg ttcatggata
    29701 actgttggaa tacccatttt ggctgcagcg tacactaccg ctccggaaac atatcctcca
    29761 gtaccgataa cgatatctgg ttgaaaatca ctgaggattt tttttgcttg acggatactc
    29821 ttaagaaaca atcggaccgt cttgatgtta tgcatggaaa tttttcgttt aaatccttga
    29881 atctccaagg tatggaaagg cattcctgta tcagggacga ttttgttttc tagacctcgt
    29941 tttgctccca catacatgaa ttcagcattc ggttcttgag tctttacata attgacaaag
    30001 gcaagagctg gataaatatg tccccctgtt cctccgcctg taaccaaaat tttcattttt
    30061 tatcgctcgc ttctactttt tctattttaa tcggttcaca gcttccatga atctgtttcc
    30121 tctagtttca aaatttgggt attgatccca gctggcattc gctggtgata ataaaactac
    30181 atcaccatct gtactgtttt ctaatgctaa aggaactgct tgttctacag aatcggctgt
    30241 tactattgtc tcgatgcctg ctttttttcc agcatccatc aacttttctt ttgtttggcc
    30301 aaatacgacc attgctttga ttccttttaa tgaaggaatt aattcatcaa atgtatttcc
    30361 tctgtctaat ccgccagcca ataacacgac cttagacgtt tcaaatccac ttagagccat
    30421 tttagtcgct aaaatattgg ttgcttttga atcattataa aattttctgc cttggatttc
    30481 tcctacatat tgcgtacgat gtggtacgcc atggaaaaaa tgcaacgttt ctcgtatagc
    30541 ttcatttgat ataccataca attttgctac agaaatagca gctagtgcat tttctacatt
    30601 atgcttacct ggtacgccaa gttcagatat ttccattatt ttttcttttt tatagtatat
    30661 tgagtaatcg tcagcataca caccgtcttc caacacttct tttgtcgaga aaggcagtac
    30721 gcgtgctttt gttctttgcg ctaattcttg tagttctgac tgattccagt taaggatcag
    30781 ataatctttt tctgtcatgt ttttttgaag gttccattta gctttgacat attcttttct
    30841 tgtaccatga taatcaatat gtgcttcata gatattggta atcaccgcta tatgagggcg
    30901 gaaatctgtg attcccatga gttggaagct agacaattcc atcacaattt tatcttctga
    30961 ttttgcttct tgcgctacac cacttgctgg atacccaata ttacccgcta aacgtgcaat
    31021 tccttgatct gctcctgcat tcagtagtag tcctgtcatc gttgttgtcg ttgtttttcc
    31081 gttcgttcct gtaatcccaa taattgggca ttccgctact tcgtaagcta gctcaacttc
    31141 cgtaattacc ggaataccca tttcttgggc ttttgctact aaaggatgac tgtagggaat
    31201 ccctggattt ttgaccatca atgaaaattc ttcatccaac aattcgattg gatgactacc
    31261 tgttattact tttatcccta aagaaagcag ctcttgtgct tccggatttt cgtcaaaagg
    31321 ttttccatca ttaacggtga caagtgcgcc caattcatgt aataatttgg ccgcacttac
    31381 tccgcttttt gcgagtccta agacaagcac tttcttattt tcatatgttg atattttttt
    31441 catttcccgt catctcctac caaacgatcc ataatgtgat caacgaagtc acaatgctga
    31501 tcaaccaaaa aactgtatca atcttccact ccgaccatcc gcacatttca aagtgatgat
    31561 gaattggaga cattttaaaa attcgttttc ctgtaagctt aaaggaagta acttgaagca
    31621 tcacacttgc tgtttccata acatagatca aaccaatcaa aagcaatgtc cattcttggt
    31681 ttagcattat agaaattgcc gctaaaagtc cgcccaacgc taatgaaccg acatctccca
    31741 taaaaatctt ggcaggtttt ctgttgtaga cgaagaaacc cagtaaacct cctaaaacac
    31801 ttaagcaaat gattaataca tcatactgat gctgatgcca agcaattaga ccgtaagctg
    31861 caaaagagat acttcctaag ccagcaacta atccatcgat gccatctgtc agatttactg
    31921 catttgaaaa tccaacaagc cagaagagag cgaaaatacc ataaatgatt cctaaaggta
    31981 gatctagtcc gaagaaattc aatacacctg gataaccttc agaacggtaa acaagataaa
    32041 agatgattcc ccctagaatc tgtccaatca atttctgctt cgagttcagt cccatgtttc
    32101 ttttcttgaa tatttttata aaatcatcaa gaaagccgat tactccgtat aacgctaata
    32161 caaaaagcaa gatgaaaaga gtaggagtta gctgtttttg ccaagctcca acccaaattc
    32221 ctgtcaaaat agagccgatc agaaacacta agccgcccat tgtaggagtt ccggctttgc
    32281 tattgtgcca ctttggtccc tcctcacgaa tcgcctgacc ttgctttttc atttgaaaat
    32341 aaccaataaa tagcggcatt gcggcaattg tcattgcaca actgctgaca atgggaatca
    32401 atgcttgtgt ccattccatg ctcttttctc tcctatttct cttcttattc ttctaaagta
    32461 aaactaagtt tgtcttcagt gattttttca tatggagcaa gttcttgttt gacacaataa
    32521 ccatctccat caaaactaac ttcaataccg aggattttcc ccagcttcat gatatctgct
    32581 tttgaccatc ctgttacgtc aggcatcagc ttatcaccac cagtatatag gatcagtttt
    32641 tctccagaga tcaactgatc accgttggca gtagattgtt tttgtacttt tttaccatta
    32701 ccgatcacta caggttgcag tccacttttt tgagcatcag ctgctgcaac gtccgcttca
    32761 agattacgat aatcggctac ggatactttt tctgtttttg tttctgtatc tgaatcttct
    32821 tcagtttctt taaaatccat tgcccgtttc atcaatggat ttgcgatttt agccaatgcc
    32881 attcgatcat atgtcttagg gtgtttcatt gttagataca agacatagtc tggatcttca
    32941 gaaggaacca tctccacaat cgaatacagg taggctgtat ctcctgtttg atatccccct
    33001 gtatcagaag cgatttgggc tgttccggtt tttgccgata cattgtatcc aggtacacta
    33061 tatacaccat aagcaatacc gtagttttcg ctttcgacaa catctctcat atattcacgg
    33121 actttttctg ttgtttcttt tgaaaaaggt tgccctagaa cttctgtttg agttgttcgc
    33181 tcttctccag tttggggatc caccactttg ctgatatatc gaggttgaat cattgtaccg
    33241 ttattcgcaa tagaagtgaa agctttcatc atttggaaat tcgtcacacc taccgcttgt
    33301 ccataagcac tcattgctcg gtcgacaata tttaatgtag gtaaagcacc gtttacttca
    33361 tcatctaatc cagaatgagt actttgtcca aatcccagtt tttgtaaata gttataccat
    33421 cgtccgccta atcgctgttc cagtatgacc atcccgacgt tacttgacca tgaaagagct
    33481 tgacgcatgg tcagcacacc tttttcacca aagtcatggt cattgatcgt agcatcttct
    33541 acttggattt ttccagattg gaaggtttca ttctcgttga attctccttc ttcgatagca
    33601 gctgcagtag tgaaaacttt catggttgat cctggttcat aactatcttg taccaagaaa
    33661 ttacgccaga tagcatcttt tccagtcaat ccttccattg tttcaggatt gaaagtaggt
    33721 cgttgtccca ttgccaagat ttctccggtt tttgctttca tcaggactgc tgtcaattct
    33781 tctggctgat attcttcatt tacttgatcc atcagtgttt ctaaataact ttgtagtctg
    33841 ctgtctaaag tcgtgtagat atcttgtccg tcgacagctt tttcttcttc tgccactgta
    33901 cctggcagag gattttgaaa attatctttt tgataaataa tcttaccatc tttaccgctc
    33961 aagatatcat tgtaagcaga ctccaaacct agtttaccaa ctaagccatt ctcatctttg
    34021 tctggaactg cgtatccaat aaaatgagaa gaaaagacgc catttggata catccgagcc
    34081 tgatggtcga caaaataaag accagcgaca ccttcttttt tcatgtccgc ttcgatgttt
    34141 tgcttggttt cttgggagat atttttccca tagctaccaa attcaacttg atacagctct
    34201 ttttttgcgc cgtcctctaa aatattcagt gcatcttttt tgtctataga aagattctta
    34261 tgcaggattt ctgctatttt atcaaaattc ttttcttcaa catacagttt tttatcccca
    34321 gaggtatatg tttttgagag tatcgcttta attgaataag aggaggcatc ttctgcgagc
    34381 gccacaccgt tacgatcata aatcgttcct ctttttgctt ttactacttc acttccttgg
    34441 tacaactgtt ttgttttttc agctaatgag gtaccagcaa catgacctcc aataacgata
    34501 tacgagaaac ggacggcaaa taaaaagaac aatccaatac tcgtagcaaa taaaatgata
    34561 cctacttttt tgcgattgtt catcggattt agatttttct tttccataaa ccgccgaatt
    34621 ttatttttaa gactcattta cttcactttc cttaaattgt cgtcattaat agacaatcct
    34681 ttttcttctg cgatttgttt aatccgttca gtacgagaaa gttcgttttt ttcttgttct
    34741 aaactcgttt tttcttgctt tttatcattg atttctgttt gtattgacgt gatttctttt
    34801 tcagctccgc tgatatttgt gcgcagcata actgttaaaa cacataaagc aacaatagca
    34861 atcgccacgc ttgccacagc aattttttcc aaagcagaaa tctgctttaa tcgttttgcc
    34921 ggtgattgtg gaagaatgat ttcttgattc gaagaagaat caggcatttg ttgttccggc
    34981 tgatccacca attcaggtaa atcatattcg taatcttgca ttttctttaa ttctgccatc
    35041 attctactcc tctttcattc ttattttttc tgcaatacgt aactttgcac tgcgtgatcg
    35101 attgttttct gttagctctt cctctgaagg aaggattggt ttacgagtaa tgactttcag
    35161 ttctggttgg aattcgtcag gtatgacagg aagtcccggt ggtagatctt gtaccgtact
    35221 atattcttta aacatacttt tgacaattct gtcttccaat gaatggaatg tgattacgct
    35281 gattcttcca ttgactttca ataaccggat tgcctgttct aaagaggcct cttcggcacc
    35341 gagttcgtca tttactgcaa tccgcacagc ttgaaaaatt ctttttgcag gatgcccgcc
    35401 ttttcttctt gcgggagctg ggatgacttg tttaatgatt tcgacaagct caccagttgt
    35461 ttggattggt tttgtttttc gtactcgttc gatttcacga gcaatttgtt tggaaaattt
    35521 ctcctcgcca tagcggaaga aaatctttac taattcatgg taggaatatt cattaattac
    35581 gtgataagcg gataaaggag ctgactgatc catgcgcata tccaacggtg catcttgatg
    35641 ataactaaat ccacgttctg cttcatctag ctggggagag gaaaccccta gatcatacaa
    35701 aatgccgtct accttatcta catgctcact caagcgttct tctaattctc tgaagttcgc
    35761 tttgataaat gtgaccatac cttgttcgac ataagaagct aaacgcagct tggcgtgatc
    35821 gattgctttt tgatcttggt caaacgcata cagatgccct ttagaactta gttggcttaa
    35881 taaatattca ctatgtccgg caccgccgag tgtacagtct acataaacgc catccggttt
    35941 gatgttcaat ccatctaccg tttctttcaa catgactgta tagtgttgaa atgtttcagt
    36001 cattagtcag cctcttccta ttcttatagt ccgaaatcaa tcatactttc agcaatttcg
    36061 tcaaagttct cttctgctgc tgcagaaaaa tcttgccatc gtgtctcatc ccaaatttca
    36121 attcggttag atacaccgat gactacgcaa ccttttgtca aagctgcata atttcttaac
    36181 gtgctgggta tattgattcg tccttgttta tcaagttcgc attcagtggc agccgaatag
    36241 aagaatcgca caaaagtacg tgcgtctttt ttagccaacg gcatttcgtt cagtttagct
    36301 tccagatttt cccattcgct catcggatag ccgaaaagac agccatccaa tccgcgtgtc
    36361 agaacaaact tttcgccaag ttcttcacga agttttgagg gcacgattaa acgtcctttt
    36421 gcatcaatat tatgttggaa ttcacccatc aacattgaaa gccccccatt cctccactaa
    36481 ctaaaattag tctaccacaa tcccccactt tctaccacct tttctgggaa atccgggaac
    36541 aacttttttt attcataaac atttttttaa aaatcaagct gcaaaaagcc ttttaaaaga
    36601 ctttttacag cttttctatt tttttcatag gtaagaaagt atgttcacaa tgatcaagac
    36661 agcgtacaag acgattgtca acagaaaaac caaacgccaa gtcatcttga aataacgcgg
    36721 ataaataatt tcttcataat aatatgcttg gaaaacagca atacaaattc ccattagcaa
    36781 aacagaaata aagaaaaacg gtaagataga aattgtccct gtatttctag acaatgcatg
    36841 cataccgccc cacaaaaaag gaatcgccaa atcaggggct tttattttaa aacgacgatt
    36901 taacgaaaat aattttacaa gaaattggca accaaacaaa acgattaccg ggtaaatata
    36961 ccaaaacaag ataagtggtg tgaatgtgcc catgaacgta aactcctttt ttatcgttgc
    37021 ttcaagtata ctgtatatac tttacacaac tgtttcattt tatttaaatt tatgcagtta
    37081 tattctatat cttacaaaca cattccatgt attccaattc cctatccgtt ataataaaag
    37141 aaacaggcaa caggaggaaa atcatgatca aatattttac attagataat gagaaactgc
    37201 gtaataccgg aaaggaaact gaccaaacga tctggtattg tgtagaacgt cctaatcaag
    37261 aagagattca tcagctgaca catcaatttg aaattccgtc agattacatc acttccatat
    37321 tggacgatgc agaaaattcc cgtacagaag aattcaatca atcaaagttg acaaagccag
    37381 cgttattatt gttacaatat ccttttgcta aaacaagtcc tagcggttat tttcaagtgg
    37441 atacataccc gctctctatt attttgacgc ccaaaaagaa gcttatcaca attacgaatc
    37501 atgaaccact gtttttaaag aaagtcttta gccagacctt tccaaaaagt gatatttcgc
    37561 ctaatctcaa tatcttcttt caattcattt ggcaggtcac actctcttac aacagttatt
    37621 tagctacgct tcaatctcaa tgcgatactt tggaagccaa acttcaagta tccactgaaa
    37681 acaaacaact ttatcaaatc atggatatcc aaaaaagcct cgtttatttc agagaagcga
    37741 cttctgctaa tttagatgca ttgaaagaac tagcgcaaaa taaacttttc caagaaaatc
    37801 atgctttgaa aaatcattta cgtgatgtat tggtggaaac agagcaggca atgactactt
    37861 ctcgcattca attaaaacta gtagaacaaa tgaatcagac tttttcagca atcgtatcga
    37921 ataatctgaa taatattatg aaaattttaa cttctttaac gattatttta actataccga
    37981 caatcgtcgg cagtatctat ggaatgaaca ttaagttacc tattgctgaa agggatgatg
    38041 cctttatatg gctagttcta ttaacattat ttatttgtat cgtaactacc tattatttaa
    38101 aaaaagggaa gtttttataa aaaagccctc ttgtggaaat ggaaaaaaga ttgtacactt
    38161 gaatcaacta attaatgacg aggttgaaaa caatgcgtga aaaaaaacaa acaagtactt
    38221 ttgctaaagt aacaaaattt gtcatttgga caatgctgat tttaacgatt ggatctgttg
    38281 tattgactgc tgtaatgagt gtcatgtaaa aataaaatat agctatcagc tgctgaaaag
    38341 gacctgaacc actgcgaggt ggctcaggtc ctttttgcga gtttcaatag ttcttttgca
    38401 tgttcgagtg tgagttttgt aatctcactt ccagccagca tacgtgcaat ttcttcttct
    38461 ctttcttttg ttttcaactc tgaaacagaa gtttgcgtac gtccatcaat cactgctttc
    38521 acaatataat attgatagtc ggcgactgca gcaacttgag gcagatgagt gatgcacaaa
    38581 acttgagagt atttcgatat ttgagaaatt ttatctgcga tggcctgtgc aactcttccg
    38641 ctcacacctg tatccacttc atcaaaaata atacttgtca caccttgctc agaagaaaaa
    38701 atagttttca aagcaagcaa catccgagac agttcgccac cagaagcgac tttcaccaaa
    38761 ggcttcagtg gctctcctgg attggtcgta atgtaaaatt cgatttggtc aaatccatca
    38821 tgattcaatt gtctattttc ttcttttaag aaacgtacct caaactcagt gttttccata
    38881 tacagacttt tcaattcatg cagaatggat ttttccaatt cttttgcgat ttttttacgc
    38941 gcttcatgaa gatctgcggc ttgttgctga agtagaagct ctttttgctc tagttcctct
    39001 ttcattttgt ccaattgacc ttctgaaaaa tcagaagaag ctagctcttc ggtgatttcg
    39061 tcatagtaag ccaatattga ctcaatggat tcgccgtatt tacgtttcaa ctgtcggatt
    39121 aattctaaac gttgcgtaac ttcttctaaa cgactctcat ctaactccaa taaatcaatc
    39181 tgacgactca tatcgccgat tgcatcttgc agcaaatagt aagcactttg gatattttca
    39241 taaattgctt catactccac atctagatgg gcgatccctt gcagttctga aacggccaag
    39301 ccaacaccat ctacactgtt ttgttcatta ttcgtcagtg ctccgtaacc tgcagctaat
    39361 ccatcagcaa ttttttgata attgctaagt ttttctcttt cttcttttaa tttctcttct
    39421 tctccgactt gcaaatcagc agcagctatt tcttcttgct ggaaatggag catatctatt
    39481 ctctgaacat aggatttttc attttgctgc acttttcgta cccttttttc cagctcacga
    39541 taagagatat attcttgctg ataactcttt ttcttctgtt ggaaagctac atctccaaaa
    39601 cgatccaata aagcaagatg tgattcaggc tggagcagtt cctgatgttc gttttgtcct
    39661 tggatatcta ctaaataact gccgattctt ctcagattag ctaatgtgat aatatgacca
    39721 ttcactcgac aaacattttt tccagttaag gacatatccc gtcgaacaat cagattgtcc
    39781 tcatctgttt cgatccctaa ttcaaccatc agttcagaga atccttcttg ttttggtagt
    39841 tcaaacaacc cttcaagcac acatttttct gctccttgac gtatataatc gcttgaacct
    39901 cttcctcctg ctaacagacc taaagcatcg ataataatgg atttacccgc accagtctct
    39961 ccggtcagcg cggtcattcc ttcgtgaaaa gaaagccgca attccggaat aatcgcaaag
    40021 ttagtaatac tgatttcttg tagcatcaca ttcgctcctc aacttaaagg taatgcagga
    40081 agtctttctt caataaaact gcctggtctt cagttcgtgt aatcatcaaa acattatcgt
    40141 catcattgat aatcgaaaat aattctttct tgtaacgttt atcaatcaaa tttgctgctg
    40201 ccgaagcatt tcccggcaat gttttcaaaa taacaaattt ttccatttgg tcaactgcca
    40261 cgaaagcgtc ttttaatagt ttttccaatt tagtatttac atcttcgttt gtttcagctg
    40321 gtatgctata acggtagccg ccatctgaag ccggtacctt gatcagtttc agttccttta
    40381 tatctctgga aatcgtagct tgagtaacag atattccttt gcttttcagg atttcaacaa
    40441 attcttcctg ctttcggata tcttgctcac tcaacaatcg agtaatcaaa cgatgccgat
    40501 ctttttttct cattacgtct tcgctcctta gcatattctt cttaatcaat gatagcttat
    40561 ttccttggta taataaagaa gaatccgcat acttctcact tgattttcac agttacaatt
    40621 tatttatggt caaactgttc gtgtgcattt gaaaccactt ctgccatatt aatagctgaa
    40681 ttgattgttc cgctttcggg tactttcctc aagtgagcca agaactcgat atttccttct
    40741 ccccccgtga tcggagaata acttaattcc agcacatcat atccaccttg tgccgcaaat
    40801 gacaaaatgt cttctaaaac tttttgatgg gtctgagggt cacgaacaat tccgtttttc
    40861 cctacagctt ctctgcctgc ttcgaattgg ggtttgatta aagcaatcac ttctccctct
    40921 tcttttaaaa tagcatgtaa tggaggcagc atcagtttta gtgaaataaa agaaacatcg
    40981 ataacagcaa cttctggaat tcctaaggta aagtcttcgg gttttgcata acgaaaattc
    41041 actctttcca ttacgacgac tctaggatct tgtcttattt tccaagctag ctgattgtag
    41101 ccaacgtcta aagcataact catttttgcg ccattttgca aagctgcatc agtaaatccg
    41161 ccagtggatg caccaatatc taacaatgtt tttccttcaa cagatagatc aaatgctttg
    41221 agtgcttttt ctaattttaa tccccctcga gaaacataag gaagtttttt acctttgact
    41281 cttaattcac tactcactgg aattttttct cccggtttat caaaccgctc gtttttttcg
    41341 ttgtaaatca aaccagccat cactgaacgt ttggcttgtt ctcttgtttc aaataatcct
    41401 tgtttgaccg ctaatacatc tacgcgttct ttttccattc tttccctcat ttctccacat
    41461 caaattgctt gatcatctgg cgcatcagcc cgccatcaaa agaaaaaacg tcctcttcta
    41521 atttgtctat gatcttgttg gcggataaca gctcaatctc caacgcctca cgtgtctttt
    41581 ctaggcctaa taaacgcggg taagtatttt tttccatacg ttcatcttta ccagctgttt
    41641 tccctaatgt tttcgttgta ccaatcacat cgagtagatc atctcttatc tgaaaagcta
    41701 aacctaaatg ttcggctaat cgttgaagta gcaataagat ttcttcaggt tgcttcgcta
    41761 atatgccacc agccagcaag gcataacgaa tcaaatgccc tgtctttctt tcatgaataa
    41821 atgctaattc ttctaaagaa agctttttcg attcgccctc gatatctgca gcttgcccag
    41881 caaccatacc ttgtgatccc gcacaaacag ctaattgctg aagcagcaga agcttaggag
    41941 aattacctaa gtgtgccata ctgattagct ggaatgctcc tgtaagcaaa ccatctccgg
    42001 ccaatatagc taatgcttcg ccgaatactt tatgattggt aggttttcct ctacgaagat
    42061 catcattgtc catcgcaggc aaatcatcgt ggatcaagga atacgtatgc accatttcta
    42121 aagcagctgc tacttgatag acgggaacat caataggctc atcaaaggaa gcaacggccg
    42181 ttaaaagtaa taagggacgt attcttttcc cgcctgcttt cactgaataa ctcatcgcat
    42241 catagagtcc tctatccgtt gtatgctcat ctaaaaaaga caagatttct ttttctacag
    42301 caggtagatg aatagctgaa aagtcagtta atctcatctc agctttcctc gtttccgtca
    42361 aaatcaactt cttcatttga ttctgtcatc attttcgtca aggtctcttc tgctttagct
    42421 aatgtatctt ggcaatgttt gcttaattcc attcctcgtt taaacgaatc tagagctgat
    42481 tctaatggaa cgtctccttg ttctaactgc atgacaattt tttctaattc ttgcagtgac
    42541 tcttcaaaag ttggattttc catattttta ttctcctttg tctatctctt gtacttgtcc
    42601 tttaacgatt ccatcttgat aatggatcgt cagcaaatcc ccttgatgaa tctcggtgac
    42661 actttttact acttgatcat ttaacgtcgt atagctgtag cctcttccca tgattttcaa
    42721 tggactcaac aaatcaagag attgaacagc ttgagcaaaa cgctgctgct gttgtttcat
    42781 atattgttgg attttctctt ctaagcgttt ttctagataa gcagtttctt ggcgagctgc
    42841 tttaactcga taaagcggag ccacttgttc caattggtgg cttaatgcga tcgtttgttt
    42901 ttctttcgca tgataaattt gctgtgtagc ttgatataat cgctgtttca actggtctaa
    42961 tttgatggtc tgaccttcat acaatctttc aggctgccga aatacatagg aacgtcgagc
    43021 acgctcgaac cgttcttgtt tgcgctggat ctggcgtaca aacgcctgct gcaatctagc
    43081 ttgccgttct tgaatgcgca tcaactcttc tgacaaaaca ggaacagcta attctgcagc
    43141 tgctgttgga gtggcagccc gaacatctgc tactaaatca gcgatcgtgg tatctgtttc
    43201 atgtcctaca gatgaaatca ccggcgtatt agcttgataa atcgcccgag caacccgctc
    43261 ttcattaaac ggccataaat cctcaatcga accaccccca cgaccgatga tcattgtatc
    43321 gaaattgccc atctcttcta ctctctggat attcctgaca acattgtccg ctgcttggtt
    43381 tccttgtaca actgttggga acaaaaccaa ttggacaatt ggatatcttc ttttcaccgt
    43441 cgtgatgata tcgcggataa ccgctccgct tggactggta aggaccgcga ttcgctttgg
    43501 gaaacgtggc agcatttttt taggcccttg aaaaaggcct tccttcatca gcttttcttt
    43561 tcgttcttcc aattcttgat ataaagcacc tattccatca ggctccatgt gctctacata
    43621 gatttgataa gaacctcccg cttcatataa tgaaatacgc ccaacgacaa ggactttcat
    43681 tccttctttt ggctggaatc gtaatttttg gaatgctcct ttgaacataa tagcagatat
    43741 ttttgcatgg tcatctttta agctgaaata ttgatgggca ttggcacgta aacggaaatt
    43801 cgatatttcg cctgttaaat atacgcgttc taaataagga tcggcatcaa attttctttt
    43861 caaatacttc gttaatgtag tgacagttaa atattcttgt gccatctatt cacctgctcc
    43921 aaaagcttcg gcagatttta cggtttgata catcagcatc gtgatagtca ttggccctac
    43981 accctttggc acaggagtga tccagcctgc aataggctcc acttcatcaa atttcacatc
    44041 accgatcagc ttaccgttag catcacgatt catccctaca tctatcacta cagcacctgg
    44101 ttttacgaat tcttttgtga caaaatgtcc acgtcctatt gctacgacta aaatatctgc
    44161 ttcttgtgcc agttcagcca gattttcggt tttagaatga gcaacagtaa cagttgcatc
    44221 tgccatcaag agtagctgag ccatcggttt accgacgata ttgcttcgtc cgataactac
    44281 tgctcgttta cccgccggat cgatagaata agcttcaaac attttcatga tgccgtatgg
    44341 agtacaagga atcttgtccg gtttacccgc aaggagtctg cctaaattca tcggatgaaa
    44401 accgtctacg tctttttcag ggcggatagc taacaggatc ttttcttcat ctatatgctt
    44461 tggcaatggt aattggacca atataccatg aaaactagga tcttgattgt atttttcaat
    44521 ttctgcaagt agttcgtctt cagaaatcgt ctcaggataa cgctctacca atgaatggat
    44581 tccgatttct tttgctacac gttctttatt tcttacatag atttggctgg ctggattttc
    44641 ccctaccaat aaaacgacta atccgggatg gataccatta tctttcaatt tttggatttt
    44701 ttcagcaatc tctgcctgca ttttttcagc taattctttt ccgttaatca attctgccat
    44761 ctaaccactc ccagatattt tttgtgtttt cattctacca tagaattttc ccgatttata
    44821 acaggtttat gatgattcat agaaaaaagc taggacttac gccccagctt ctaattcttt
    44881 caatacattg gataaaacac cgttgacgaa tttacgtgaa cggtcatcac taaatgtttt
    44941 tgccaactcg attgcttcat ttaaagcaac agccgctggt acatctgtca cataagtcat
    45001 ttcaaaaatc gcgatacgca agatcaccaa atccattttt gagatccgat tgatgtgcca
    45061 attgtttttt aaatgttttt caatcacttt atccaattca tctttttttg cacagacacc
    45121 gccaactagc gtatcaagat aaacaggaac aaactctgat tcatcttcgt tgatcatgtc
    45181 gcggtggtct aattcgattg cgttgaaaat cgcatcttct tttgttaggt ctgcattgaa
    45241 gtctaatgga aataaagcct gcaatgccat ttcccgaatc tcgtgtcttg ataattcttt
    45301 attcattctc ttcctcttcg tcttcaaaaa gttcttcgat tgttggttgt tctaattttt
    45361 caggaacaac agctactaca tggatattga cttcagataa atcgatatcc gtcatgaaaa
    45421 ggacttgctg gctgacccgt tcctgcattt ccattgctac tttaggaact gaaacaccat
    45481 attctagata acagtaaaga tctactttca agccatcttc ctcgtttgct aagtaaacac
    45541 cttttccgtg agctgcacgt cctaataatt cagtgacatt gctggcaaaa gttccgcgca
    45601 ttccgtatac gccttctact ttagaagctg caatcccgat aattacttcg atgacttcag
    45661 gagcgatcac gatctctcct aaatcttggt ttgcgtttaa aatcaaattt ttttcatctg
    45721 ccatttattt attcctccct ttgcctaagc acgagataca tccgaattct ctatgatgcg
    45781 gcatagtgat cacgtggtaa gaaaactgcc gccgatcagc tgcaaactgc tatgaattgg
    45841 agaaaacacc caactttatt atctcttaca gcttaaaagt tcttctatag tgtatcatta
    45901 aatcgagtga ttttctataa caaagtctgt gaacactgat ttttacgctt acttcttcta
    45961 ttgatgaaac tataagatga tcaattcttt tggtgaacga gtcaacacac gatttccatc
    46021 ttctgtgatc aacaagtcat cctcaatacg tactccaccg attcctggta agtagatccc
    46081 tggttcatca gtgatcacat ttcctggtac aaattgcttt tctgcacgag aagaaacgtt
    46141 tggtccttcg tggatctcta aaccgatccc atgtcctgta gaatgtccaa atgcttcccc
    46201 gtaaccatgt tttgaaatat aatctctagc aactgcatct aattggacac cagtcattcc
    46261 tggttttgca gcatcaataa ctgctaattg agcatctaag actatttgat aaatttcttt
    46321 taatttttcc ccaggatcac caatagcgaa tgtacgtgtc atatcggaaa cgtacccttc
    46381 gtaatagcaa ccaaagtcca atgtgatcaa gtcaccttgt tcgatgattt ttttgcttgc
    46441 tacaccatgc ggcatagccg aacgcaatcc gctagcaacg atcgtatcaa aagaaacacc
    46501 tgaagcgcca agagaacgca tataaaagtc tagttgattt gcgacttcaa tctcagtcat
    46561 gcccggttgg atcattttca ggatgtgatc atatgccata tccgcaatat gacatgcttt
    46621 ttcgataata gcgatttctt cttcatcttt cacttctctg agttcttcga tcatctgtga
    46681 aacaggtact aattccgcat cgatgatttc ttctaaaacc gaatattcta aaaatgagac
    46741 tgttgtttcc tcaaaagcta atgagtgcag ttcttctttg cgtactaagt ttgctacctc
    46801 atcaaaaata ggtccgacat ttttaataat ttcaaaccct tgagcctgcg ctgccgcctg
    46861 ctcggtataa cgaaaatcag taataaaaaa tgctttttcc aaagtaataa cagctaatcc
    46921 tgtcgtacct gtaaagttcg ttaagtaacg aagattgtac ggactggtaa ccaaaaatga
    46981 atccaaattt tcttcttgca tttttttgcg caatttttct acacgtagca tcataatgaa
    47041 actccctctt tctttgcacg cttttttcca ttatagcaaa cttttcttcg tacacgacag
    47101 ttaaataaaa atttccggaa aacttctttt tattttaaat aaataaagcc aaaaaggagt
    47161 cacagtctcg ctgcaactcc ttttagttta ctattttgta aaaacttatg atcgttttcc
    47221 aaagaaaaat gagacaactg ctaccaaaat cactgcgcct aaaatagatg gaataagtgc
    47281 catacctgca gcttttggtc cccattcgcc gaaaatcgct tgtccaatac ttgaaccgac
    47341 tagtccagca atgatattcg ttacacagcc catcgaattt cctttactgg tgatcgcacc
    47401 tgcaattgct ccgatcacgg ctccaacaat caatgtccat aaccaactca taatataacc
    47461 tccttctttg ctaatcaatt ttagcatatg ggatttaaag gggacaaata attggttttg
    47521 ctatttcata ttttcttctg caaagtaaaa aaataaagaa aacctcctct tagaagtttt
    47581 ctttattttt tacttgcgtt taaacatact acgaatacca cgtttcacta catcaaagaa
    47641 actcaatgat tgtaccattc tatcttcatc tacatattct ctgatcgcac gaagcacttt
    47701 tttaggttct ttggaagaaa atgtgtatgt accatttttt ttcgtttgaa tggcatatcg
    47761 aggaatccat tttcccttta gcatgactga tgctagtaca taatccactt cttcccatgg
    47821 aatttggata tatttgcgtc tatctcgcgc atggtaaaac tcaaaaccat tatcacctat
    47881 catgatttgc ccgtaatctg tcagacccgt aaacgaagta gcatcaatta ccaagtctac
    47941 ttttgtattg attgattgaa ccattttctc cctccagata tttgtttatg aacagtatac
    48001 tatataaaaa aagctcggga caacgcccga gctatatttt tatggattat aaaagtccga
    48061 tgacgtgtcc aacaacaccg actacgaata aaccaaggat gataacgatt ggagaaacct
    48121 ttttcttaag caaccacata cataacaatg ttaatcctaa tgcagctaaa ccaggaatca
    48181 attggtctaa gttgtcttgt aatgttgtta ccttttcagg agaaagggct aagccattat
    48241 taacttgttc aaatgcactc ttgattcctt caccacctga aggcaattta tcccattcga
    48301 tgtaagcacc tttatctaat tttacagttg atacaactgg taagaatttg attgataccc
    48361 atctttgtac aagggcagct aatacgaaca tccctaaaat tgaagcacct tttgttacgt
    48421 cttgtaacaa tccgccagaa aggtcatcag taattttaga accagctttg tagccaaatt
    48481 cttgtgtata ccacatgaat gcccaacgaa taatgttcca acctaagaag aagatgattg
    48541 gtccaaggat atttcctccc atagctaatg aagcacctag tgcacctagc attggacgta
    48601 ctgtaaacca gaacactggg tcaccaacac cagctaaagg acccatcata cctactttaa
    48661 ccccttgaat cgctacatca tcaacaggcg cgccattcgc acgttcttct tccagagcca
    48721 atgtaacccc taaaattgga gaagcaatgt atgggtgtgt attaaagaat tccaagtgac
    48781 gttttaatgc tgcagaacgt tcttcttttg ttttgtataa ttttttgatt gctggaatca
    48841 tagaaaatgc ccagccaccg ttttgcatac gttcgtagtt ccatgaacct tgaatgaagg
    48901 tagagcgcca cgcaacagct aaacgatctt tttttgataa tttgattttt tcttctgcca
    48961 ttttattttc ctccttcaag attaatagtc attcaaaatg tcgcctaaag ggtcaccaga
    49021 gttgcttccg cctccattat ttgatgaacc acccatttta gaaaggttca agtaaataag
    49081 agctaatgca acacctaaag cacctagagc aatcaatgtt aattgagaaa ttgcagctac
    49141 aacgaaacca ataacgaaga atggccatac ttcttttgta gccatcatgt tgattaccaa
    49201 agcgtaacct acagctacga ccattccccc accgatagcc ataccatctg ttaaccatgc
    49261 tggcattgat tcaaggaatg attgcacagt ttgtgctggg ataaatagca acgctgctgc
    49321 tgggaccgcg atacgaaccc cttgtaaaca tacagcaatg atgtgccaca tttcaacctt
    49381 acggatgttt ccttcttcag cagccgcatc catcaaatga acgattggaa cagcgattgt
    49441 acgtacgatc attgttaaga acaaccctgc aacagccaaa ggaacggcaa tcgcgatcgc
    49501 agaaggaaca cctttaacac cttgtccacc taaaactaaa ataattgctg atgctactga
    49561 tgctaatgca gcatctggtg ctacagcggc accgatattt gcccaaccta aagcgatcat
    49621 ctgaagcgta ccgccaagta cgataccagc ttcgaggtta ccggtaacta aaccgatcaa
    49681 tgtacatgcc actagtggtt gatgaaattg aaattcatca agaatacctt ccataccagc
    49741 tagaaaggca actaatacga ctaaaattat tgaaataata gacatgataa gcctcctata
    49801 aattttaata ttatttatta cgcttttgct aattcagctt ttgctttttt caaaatatca
    49861 tccatgttat cgcgtgaatc attaggtact ttacgtacat cgaatttcac acctttttgt
    49921 tcaagcttct caaacgcttc aacgtcttct tgtcccatag acaatacttt acttacaacg
    49981 actttaccga ccgaatgcgc cattgaccca acatttaatt ctttgatgtc tacgccacct
    50041 tcaacagctg tcaatacgtc ttcaggattt tcaaataaaa gcaatgcttt ggtatttcca
    50101 aaacgagggt cttttgctac ttcgatcatt ttgctaatag gaataacatt tgcttttaca
    50161 cctggaggag cagcttgttc gattagtctc ttacgcagat catcctttga tactgcatct
    50221 gaaacaacga taatacggtt tggttgcact gcttttgtcc aagctgtcgc aacttgtcca
    50281 tgtaacagac gtgagtcaac acgtgctaat acatatttga tttttccgtc tccgaccaca
    50341 gttccttctg gaagtgctcc tttaggttgt gcgtcttcaa ctgctgcttt cggtgcttct
    50401 gccggttcta attcttccgg ttttactttt acaccgtctt ttgctgtttc aatgatgtgt
    50461 gctgcaattt catgagcaga ttccattgaa aagcgtgatg cgtaggcttc aatcaacatt
    50521 ggtaaattca aaccgctgac gattgcccat ttatctttgt gctcttcgaa taatgtgttt
    50581 gattgattga acggtgttcc gccccataaa tcaactaaga ataacacttc gtcttgatta
    50641 tcaaaagaag caaccgcttc ttccaatttg gctctcaagt catctggacc ttcacttggt
    50701 ttcaaaatca cggctttgac gttttcttgt tcgccaaaga tcattgaacc ggattgtaag
    50761 attccttcag caaattgtcc atgacttgct aggataatcc ctaccatatt tatacctcct
    50821 atttactttt gttgtaacaa attcaaaaat attaataatt gctaaccatt acaacagaat
    50881 tatttgacct tttccaacaa ccattcttgc tacacctttt tgattttcgc tagtagttcc
    50941 atcaaaagga ttttcctgtc agcaggtact tttcgaatct ctaactccac ttcttgactg
    51001 ttcaagtaac gaaaggaatc aatatcttgt tgatttactg aaacaaaatt ggtaatcatt
    51061 gatttgcctt cagtaaaact cataccgccg atattcaacg acttcaactg tacaccgcag
    51121 cggacaaccg cttcaacatc ttggggattg gtgaataaaa gcatcacttt tgctcgtgat
    51181 aataatccac tatgatagat ttgaatcatt ttctgcacgg ttattacatt tgctgtgatc
    51241 cccggcggtg cagcttcttt tagtagaaac tttctcaatt tatcttgagc gactacatcg
    51301 ctgatcacaa tgatacgttc aacacctgtt tgcttcgacc aaactgttgc gacttgcccg
    51361 tggattaaac gatcatctat acgtgccaat cgaatatcca tctgcaaaac tccttcttcc
    51421 tcactacttc acagaaaccc ctatcatttc tgtgtgaaca accacctcct agcacacact
    51481 actataagca aaaagcgtgc caactttttt acgatacact aattgaattt aaaggattct
    51541 taaccaatac acaaaaacga tacactataa aagtgtatcg tttttgtgta ttcatggcac
    51601 agtgtattct tttttatcta actgattatg gactagacgt agcagataat acatttcttc
    51661 tatcggcact tttactttta tctgatcttc caacagaaca actgaggctg ccaattggct
    51721 ataaagagga tcattcgttg tatttgtcaa ttcgttttct tccacagtca atggttcatt
    51781 ccgaataata cgttcgatca ttcctgctgt gtgcatcact aggttgattt tgaatccata
    51841 ttcttcatcg ccgattcccg tcgtctgaga gatttgtgta gaaaattgcc acattggatc
    51901 gattaactta ctaccattaa taaagatgaa gttatcagag ataaactcaa cacacgtatt
    51961 tttagctgac tcttcatcta gggagatgaa ttcagtttcc tccaattctg attccatcag
    52021 caactgatcc aaaatgactt cgatattttg atcaataaaa cgttctaaag gaataaatgg
    52081 ggcttggata ttcaaatcag taatcccagt agtagctatg atctgatatt ctttttggat
    52141 aactggcagt tcttctttca cttccacaat cgacaaagct agaacttcta attctgtttc
    52201 ttgacgcttg tttaccgctc gttcgatcaa ttctttgatt ctttgtgctg taccttcgcc
    52261 agatgcgcag atagccaaaa cagctttttt cttatgaata ggttttgctt cctgaacaga
    52321 ttctacagaa gatatttctg cgtaacctcg aaaatttttc aatgattcat gcaacatatc
    52381 tagatctgtc cctaatactg agacctttcg tacagtttcc aaaactagag aagttgttac
    52441 catatcaaca gtacgtactg gaattccagt gtctctttga atttgcgaat taaacgacgc
    52501 aagggacccc atatctacta agagtatgac cccgcttcct tcatctactt cttgtacatt
    52561 gcgttcaatt cggtccaatg ctgttttcgg atccatatcc aaaggcatgt ctactgctcg
    52621 tacgttctct gcatctaaca actgttggac aacttggacc atactgcttg ctgtgctgtt
    52681 tccgtgagct gcaacgacta caccgattct gccgcttgct tgatttgccc gtaacgagac
    52741 gagtagaacg gtcaagtaat agtcttcact ttctggaatc tccacttgaa aatacgtttc
    52801 gatataacta cgcacttctt tcgcaacagc atattcatct ggaaaatcaa aagccatctc
    52861 acggatgtta tcattcgtat gccgttcttc tcctaagttg atttttttca aaaaagaact
    52921 gatatgcaag ctcatagcat aaataaagtt ttgctgaaac tcatatggta aagatctttt
    52981 gaccattaca taaatctgat tggtcacttc tatgattttc ggatctacaa attctgctaa
    53041 tttgctgtct gcattaaaag aaaaaccatg gtctttatag aaagacttca gatggatgtt
    53101 gatatctgta gaaatgaaat gattgattgc ttcttgatcc aaaccatccg acttcagtaa
    53161 agctgcttta tctccgatga tatcatatag attataaggt aactcatagg agtccgattg
    53221 gattttcatg atcgtatcat ttggtgctac agttatcttt ggctccaata ttttagaaag
    53281 ctctgccatt gcactgcggt tgcttgctaa ttgaatcaat ccgctacgaa tcccttctgt
    53341 caaatcatcg attgtgatcg agatttcggg tgattgcata tgatttagaa atcctcgtgc
    53401 acatactaac tggatatttg acttcaattg tcctatattt ccataggtca cactgccgat
    53461 caatgctttt gctacatctt ctgtcaaaga aatctttcgc tgcgtgcggt ttgcttcgtg
    53521 ggcaatcatg atttttacta aatcgacttt ctcatttgca ggacgttttt caaaagccgg
    53581 aagtttgata ttgattggga tacgccgaac aaaagtttct aatagagaag aacctgggtc
    53641 ttctgtggtc gcacctacga tccgtacatt tgcttcatgg gatttcgttg tttccccaag
    53701 acgactgtaa gttccatgat ccataaagta aaagatcatt tcttgacctt caggcggcaa
    53761 ccggtgaatc tcatccaaaa acagcatacc gccatccgct tgatcgataa tccccatttt
    53821 ttcttcatct gcgcctgtaa aagcaccttt tgcgtaccca aataaatgac tcatcaaaag
    53881 ctcagggtta ttggcataat cagcacaatt gaaaacaatc agttccgttt cctcatctat
    53941 tacatgatgc gcttttgcaa aatgatacat cgcgtgtgca aaataagtct ttcctgatcc
    54001 ggtaggtcct gtaatcaaac aatttaatcc tcttggcgga tacaaaatcg cagcttttgc
    54061 ctgttccact gaatttttca tgctgccgtt agctccaatg atttttgcaa agatatcctt
    54121 agtatctatt tggagtgtat ttttttcttc agagaccggc gtttctttgt aactgactac
    54181 atgttttgta actggcttta cgtgcgtaac gagtgtttga tatatgtaac gtactggtcg
    54241 tccgtctgtc tttatcagtt ttccttcgcg cactagctga ttcagatctt tactgctatt
    54301 tgttcgctga atccctaaca cttcagcaat ttcctgtgtt gttactcctt gatcatattc
    54361 tgcctttgtt aaatgagcgg ttttttcttt gacatacata taaattcggt caatgcgttt
    54421 tgccaatggt atcgctcctt ttctatagac tattgtactt aggcttcaaa acataatact
    54481 atgtatttat ttctgtttcg tcaactattt acctgatttt gttttgttga taacacgcgg
    54541 atagatagaa atgttcaatt taaaagaacg aaaaatcccg atacgatttt tataatggaa
    54601 acaagaaaaa gaacactgtt taccatataa ttatttcact gatagcaaac aatatagctt
    54661 ccatcaattg aaaacgatag ttatcaaaac atcctgattc caaattggca aaaaaatatt
    54721 aagtgtaaaa agacaaagta aacttcgtag cctccactac aacttttatt tttataaaca
    54781 aaaaaggctg tgacaaaagt cttgtcacaa cctctttaat cataagattc aattaagctt
    54841 cttgagctac tggataaaca gacacttgtt ttttgttacg gcctttacgt tcgaaacgta
    54901 ctacgccatc aacttttgca aataaagtgt cgtctccacc gatacccacg tttacacctg
    54961 gatagatttt tgtaccgcgt tgacggtaaa gaattgatcc acctgtaact gtttgtccat
    55021 cagcacgttt agcacctaga cgttttgatt ctgagtcacg gccgttagat gtagaaccgc
    55081 cacctttttt gtgggcaaat aattgtagat tcatagataa caacatggtc tgcacctcct
    55141 atttatcatt aattgtttta atttggatat attctgagtt ttcagcttct atcgattgta
    55201 atcctaataa aagattttct aatagaatct cagcaatatt gttttgttct tgtgtcattc
    55261 ctgaagtgac ttcggtataa agataaccgc cttcttcttc attcatttca acaatcggct
    55321 caaaaccggc taatgaggca atcccgttga cagtgctgat cgctaacgca gaaacacccg
    55381 cacaaacgat atcacttcca taaggaccag catcagcatg cccggtcaaa gtgaatgaaa
    55441 cgatctgacc tgcgtcattt cgcttaaatg ttcctttgat catatatagg ccttctttct
    55501 caaacgctat taagcgttga tcgcgtcgat aaccactttt gtatatggtt gacgatgacc
    55561 ttgtttacgg tgtgaatgtt ttttaggttt gtatttgaaa gtaacgactt tcttttgttt
    55621 gccgtgtttt tcaacagtac cttcaacagt tgcacctgca acagttggag cgcctacttt
    55681 tgtagattct ccgcctacta agataacttc gtcaaaaaca actttttctc ctgcttcaac
    55741 gtcaagtttt tcaacataga ttgcttgtcc cacttcaact tttacttgtt taccaccagt
    55801 tttaataatt gcgtacatgc tataaagcac ctccttctga tatacttaga ctcgccatcc
    55861 gaagtgacag catatgctgt gcttattact tgttctgagc ggttgtagct gtggagtcca
    55921 caattacaac agtactagct taccagaaca gcaaccgtta gtcaactaaa tttaaaatca
    55981 aaaagtaaaa caaaaattca agcaatactt ctgcttttct atcctcacag ttctaccaaa
    56041 taaaatagtc gcattgtgtt tcttttattc ttataataaa agaaaaagga ggagcataaa
    56101 tggaataccc aaaagaactg atacaagaag cttctttaag aatgaacggc cgtcctgtag
    56161 aaggatttat cgctgggcaa ggacctcttc atcctaaact gatgctcgtg ggagaagccc
    56221 cagggaaaac agagattgat acgcatgttc cttttagcgg tcaagctgga aaagaattga
    56281 tgcaggcact ttcttcaact ggcttaacac gagaagaggt gtatatcacc agtgctgtaa
    56341 ggagccgccc gtatcgcgtg actcatcgga tcaataaacg gacacaacag tcagaaactg
    56401 tttatccaaa tcggacacct actcgttccg aagtatttgc gcatgcacca atattggatt
    56461 acgaactgat gaaggtccag ccaaaattaa ttgcgacact tggaaacatt ggtcttcaac
    56521 gtttacttgg caaagaatat acggttacca aaaatcatgg tcaactctat acagggcctg
    56581 tcttacaatt aacagaacaa aaggatgcct acgaatggtc agaaaaaaac tatcgaattc
    56641 ttccactttt tcatccagca gctattttct acaatcgctc ccttgtacct gttatccatc
    56701 aagactggca agtactagct tcacttttac agcaatatta aaaagaacag acaagaccat
    56761 aaaatcttca gtttacagtc ttgtctgttc tttttcattg ttttaatggc taattgcagt
    56821 atatttcgca tgtaaagctg tcaacgcatg agcaactgtt tgatgttgat gcgtgaatgt
    56881 atgttcccac aagtgagaaa gttgtttttc tacttctggc tgcaaggaag tatagataat
    56941 cgtttgtcct ctttgctctg ctttttcttg aaattcatca aaaactgcac gtgccgtcaa
    57001 atcaatactt ggtacgcctc gcatggagaa aatgacacca tcgtgatgat ttagttcttc
    57061 caatttattt ttgagttttt ctgaagacat aaaaaacagt ggaccactaa tatacactac
    57121 tgtccagtta ttcagctttt ccgtttctgg cagccccatt ctttgccaat cgatcgtttc
    57181 taatgaaatc gtgatagcag cgcttttgac aacaaaaaat acacagccgc cgatcacccc
    57241 gatcacgata gcaatactta aatcaaagat aactgtacaa atcatcgtaa ggataaacaa
    57301 tagaactgct gaccaatatt tattagtaaa tagctccttg atcgtttccc attcattcat
    57361 acgccaagcc gtcacaatca aaacacctgc aagtgctggc attggaatct gtgacatcac
    57421 tggcgcaaaa acaagcatgg agagcagtaa gacaactgca tgtatcatac cagctaatct
    57481 agtttgtgca ccagatttga tggccacgct tgtacgggcg atggccgcag tagcaggaat
    57541 cccgccaaag aaaggaagca acagatttcc aattccttgc gccattaatt cttgattgct
    57601 atctaagggc ttatttgcca ttcggccagc cgaagcacca catagcaagc tttcaatcat
    57661 tcctaataaa gcaatgctaa tagctggaac tgccacttgt tgcaaggcag aaaagctaaa
    57721 atctcccata ttcaaacgat tactactgat caatgtttgt ggaatcttac ccacagttgc
    57781 tactggtaaa tggaacaata gcataactgc tgttgccaaa atgatagcca gcagcgaact
    57841 aggcattcgt ttcgcccatt tttttggata gataaacatc cctaaaatga ctagccctcc
    57901 catgatcaaa gaggctgtgt ttatcggaaa tcctatcgtt tgataactac ttagtttttc
    57961 aataacgttt gtaccttccg agtgaacacc aaataaatta tcgatctgac ctaatgcaat
    58021 aatgatagca atacctgaag taaaccccgt aattacgggt gctgggataa aagaagtcag
    58081 tgttcctaat cggaaaagtc ctgctgcaag taaaaataga cccgctaaaa aagtagcaag
    58141 caatacacct tgcattccct ttgttgccgc aatagacatc aagatagctg ccatcgcacc
    58201 tgtcggacct gatatttgat aaaaaccgcc tgataaaccg ccaataacga taccggcaat
    58261 gatagccgta atcaaacctg cggccgcatc agctccgctt gataccccaa aagccaaggc
    58321 taaaggcaat gctacagcag ctactgtgat cccagccaaa agatctttct gaaatcttga
    58381 aagatcataa cctgaaaatt ctttttttag tgaggaaaca taatttttga acacctatct
    58441 aactcctttt tcatgaaatt ttctaaaata ccattcatta gaatatcata tttcatgaga
    58501 taaagtaata tttttcacaa agtttcctgt tagataaatt cttatttttt ctatatttat
    58561 aagaaaatag aaagcaatgc caacagagct agcccacctt gtttgagtaa aatccaacga
    58621 tcgctagtca aactgccata taatgcaaca aaaaaaatag atattaatag catacttgtg
    58681 atttctttag atgcggaaga aagataagct ccataaagta gtcccactcc taatagtcca
    58741 ttgtacactc cttggttctt aaacaatgtt tgaacagatt ttctgcttaa ctcttcttta
    58801 ctcattttaa aaaccctact tgtcgtgtca gaatcagttc tcaccgtttc gatatacatg
    58861 atataaaaaa attcaattgc aactagagtc actaaaattc tagatagtat cgtcatatct
    58921 tcttcctctt ttctgatgag ttttattttt ttgctcctta taattgtact cgataaggat
    58981 gtttttttat tttatttgcc tttgaaaaca aacaatattg gcacaaaaaa caaagaaaaa
    59041 ccgttagaaa cctcagtttc taacggtttt ttagcgtcac aggagggatt cgaacccccg
    59101 accgtccgct tagaaggcgg atgctctatc cagctgagct actatgacaa gaatcagcgg
    59161 aacatcaata attatagata attaaattgc ttctgtcaat acgaaatagt tatttaatta
    59221 gcaaataatg aattattttg gcccaactac taaatcaatc ttttaaaacg agacattctc
    59281 cttcagctgt tctaaggtta tcaattgaaa acaggagcta cattgacttc atgctactcc
    59341 tgtttattta gatttcctgt atcctttaat tgacttacaa atatagaaac ttttacatca
    59401 agttcgaatt gagccctcga ttcaatcgat tatctacagg ctgccataat catgtatcac
    59461 aactcgattg tttctgattc ctttgtcatt aagatcacac catcacctaa tggcaagatt
    59521 gtcgatgtca aatcgggatg atccatcaca acacgaagaa attcatttaa tttacgatgg
    59581 atagctcgtt tgccacgggg aatctcttca tctgggagca agatcgttcc tccttggaag
    59641 atgtcatcta ccatcaaaac gccacctttt cttaacaaac gtaagcattc aggtaaaaat
    59701 tcaatatatt ttgattttgc actatccata aaaataaagt catacggacc agacaactcc
    59761 ggcaagatat ctgctgcttg accttcaagc aaagtcactt tatctgtcag tcctagacgt
    59821 tcatagtttt ttttagcttt ctcgatcatg acatcgaaac gatcaattgt cgtaacatga
    59881 gcgttttctc cgattgtcgt ggccatgaca cttgatgaaa aaccgatagc tgctccgatc
    59941 tccaagattc gttcaggctg aagctgtcca agtaaaaatt tcaaaaatac aactgtttca
    60001 tggggaataa ctggtacttc tgctacatga gcttcttctt ccagtttgcc tagctcaccc
    60061 ggtaattttt tttgctgggt acgcataaaa tccaatagtt cttctttgac tacaggacga
    60121 tgcatcattt cattgcgcat actactcctc ctcttcacac attatacgaa caactgacta
    60181 aatctacaag ctgcatgagt gttttctcgt gtttcatgtt cagaagagtc gttggatctc
    60241 tggaatacat ttatgttttt aacattctta caaaaatttc tgtgttcgtc tccgcttctt
    60301 tttcaactct acaaaggtat tccatgctgt gattcctgtt aggcaaaaag caatcgtaaa
    60361 gaataacccc tgaatccatg caaatgccgt ttttgaaagg actagtccaa tatatggaat
    60421 ctgaaagatg ggactaccga taatatttct cttttttact actccaggct caatataagt
    60481 ctttgtatca gcttttgtat aaaaatcttc gtggttgttt tcaacggcta ttacgcgacg
    60541 cgtcgagatt ttttttcctg aattttcata atatgtaata atatctccga ctaaaatctc
    60601 atttgtattt ttcggtcgta catatatcag atttccttgt gcataatatg gactcatttc
    60661 tttgtcctca ataatataag gagtcaaacc aaaaattcgg ggaaccaaga cgacgagaag
    60721 aataagaatt aaaaatataa tcaacgttat agaacttata aaagttattt ttttgtaatc
    60781 aggtatcgtt ttcaacttct ttctttattc aatccttctt aatcatataa taacgataaa
    60841 tttttttcaa attatagctg taaaaatgtt tccctttaat aattatatgt ttctaattct
    60901 atttcctcat ctttatctca ttttttatta taaataattg acgttagttt aaaaaacgtt
    60961 taccctaaca ttacaagttt tagaaaggaa tacctttatg tcttttttta ataacatata
    61021 taataaaaaa gaatcttttt atttacgtat aaagtggagc ataatcatta tattatcatt
    61081 gttattttta acaggaattg cttatttctt ttattttatt ttttctcctg cggacagcaa
    61141 tcaaatgaaa gaaataaaag attcgtgggt tttctataca aaagatgatc ctgattttaa
    61201 gtttgacagc aagtacactc gtacgattcc taccgtggat aaagacgaaa cattcattat
    61261 ggaaacgaca cttgaaaaac cgttggacga agcaaattta ctaatcaaag gaaaccatca
    61321 atggattact gtatatctag gcgaaaagat tttataccaa cggaaagatt atcaggaaga
    61381 aagcaatccc ggactctcat tggctgtgat agatttacca gcaaattata tcggaaaaaa
    61441 attgaccctt acagtctcat ctccttatca gaactatgct ggactgccac cgaaagttta
    61501 tctaggaaca actggaccat tgattagttt tatttattca caatcagtgc cgcaagtatt
    61561 gacgatgata atcgctgttt ttatcgctat agggaccttt ttctatacga tctacttgat
    61621 gtataaacaa aaacgtcttg aatactcact tattctctta agttgctttg ctttggcatt
    61681 aggatttgaa gctgtatcag aagatatttt aagtggtatt ctttttgaac cattcgttca
    61741 ttctttttta tctcatttat ttattatctt aacgtcagct ttcatcatct gctactattg
    61801 gagccgaatg ttttactata aaaaatggta cggaattttt tgtacgttcc aacttttgat
    61861 ttttatcggc gttctgcttt atgcaacttt tactcctgca gaacttcctg aattaatgcc
    61921 gattgctaat attgctagtg ttataagcac tttagtcact tcacttgcat gcattggcga
    61981 agcatataag aataaccgtt tttatgtagc ttgtacacct tggatcgtct tggtagccat
    62041 tatccattgc ttgatttaca tccaaacggc attaggtatc tatcaaacaa cgatcaattg
    62101 gtctacgatt ttatatatta tcattctaat cgttattatc agctacaatc taatcgatca
    62161 catcttaaat accgacaaag atcggagaca agtagatttc ttaaaaatca aaaatgattt
    62221 gttggagcaa cattatgagc agcttcgaca gcatatccaa gaagtaaata cacttcgcct
    62281 ggaatttgtc caagagatgg agaatctgca agatttaatg catacggacc aaacaaaagc
    62341 taaaaactat gtggaaaaga tattagaaga agcaaaaaat ttcgaaatgc tgtgttcttt
    62401 ttgcaaccac caggtgacaa atcttatctt agcgcgttac cagaagttag ctgccaaacg
    62461 gaatattcag ataaccttcc aagcagatct tcccgaagaa cttcctatca acgatgacga
    62521 tctggctcaa cttttgatcc acgctttaga gcattccttt agagaaactc atgccatcga
    62581 aaatccactg tatcgaaaaa tttatttgtc gatacacgaa caagaggaac atttcgtcat
    62641 ttgttgcgaa catagtgcac attacgatac aaacctattt agtcgaggca tcacagaaga
    62701 attagatgat caggaacgtt ttgacttaat gatgatgaaa gacgtagcgg atcgttacac
    62761 aggaacacta acgcaggaaa aagatacttt cattgatcgg atcactgttc aactctctcg
    62821 aaattacccg aatcctgtat aaaaaatagc ggaatccata tatgtggatt ccgctatttt
    62881 ttattttcaa taaagtaagg taagcaattc ttctggttct atcgcaccaa aatatttctt
    62941 cacatcaatt tggctgacta tttttgatag agatgcttta tcatatttct gtccaaccaa
    63001 ttttttttcc acgtcagaga tatctcctag tccgaagaaa tcgccaaaga tttttgcttc
    63061 tttgatcatt ccttctgaga cattcaaatg gacttcaatc gaaccgatag aaaaacgttt
    63121 ttggcgagag aaattgaaat ctggagactt cccgtaattc caatcccaat ttcgataata
    63181 ttcctcagag attcgattga tttttttcca atcttcatca gtcaattcgt acgtttttac
    63241 ttcttctact gactctacgc cgaaaatttt caacaagatt tcttgacgaa attcttctgt
    63301 tgtcattttt tgcttttctt ctggaagaaa tggtttgata ttcgttacac gagaacggat
    63361 cgatttgatt ccttttgatt cgattttgtc tttttttact tttaatgcat tgactacttc
    63421 attgatatca gagtcgaaca taattgttcc atgagcaaac atccgaccgt tggtagcata
    63481 catcgcgttg ccagaaaatt tcatgccatc aatgactaga tcatttcggc ctttcaattc
    63541 cgccccagca acacccaatt catgaagtgc ttggatgatt ggctgtgtta ctttcgcaaa
    63601 gtcacggaat gaatccccat catcaggcat gataaaacta aagttcaggt ttccaaaatc
    63661 atggtagaca gctccgcctc cacttaagcg acggacaaca tgaatgccat tttcttccac
    63721 ataatctcga ttgatttctt caagcgtatt ttggtttctg ccgatgatga ttgaaggttc
    63781 attgatataa aagagcaaaa taggttcatc taaaggcatt tcttgcagca aatattgttc
    63841 aattgctaaa ttgattcttg ggtcgtggtt ttcatttggt acaaaaatca tgttcttcct
    63901 cctaaatgtt aaacactttg tcaactgcag caagttctat atcaatccct ttgcctgctg
    63961 ccttttgcgc ttcatttttc aattgttcta aatcaccaaa ctgaggtagg tgtgtaagta
    64021 caagtttctt tacgttagct gatttcgcaa gttctccagc ttcttttgaa gtgaaatggg
    64081 catgatgatg ttcatttcct tcaaaaagat aggtatctgc tagaaacaaa tcagcatctt
    64141 tcgcaaaatc agcgaaactt tccaaataac ctgaatcacc tgtaaatacg aatactttcc
    64201 ccgttgtttc ttctacgata cgcatggcgt aacatactac tggatggatt gtttccataa
    64261 aagtaatcag aaaaggacca atttttaatt cttcagcttc aaaataagga tgtccttttg
    64321 agacattttc caacgtcaat tcttcaaagt gaatggaatc ttttgtgtgt ccataaattg
    64381 aaagcaatgt ctccggattt ctcttaggat gaagttgcca gtaatactgt aatacaccaa
    64441 ggtcagcaat atgatcatga tgataatggc taaggatcac agcatctaga tcaagtggat
    64501 caaggtgttc ttgtaatttg atcagcgtag cactacctgc atcgatcaac aaattgaacc
    64561 cgtcagattg aagcaaataa cctgttgtcc cttgattttt ataaggatac gctcctaagc
    64621 atcctaaaac agttaatttc atcgtacatt ccccctcaaa gatttatcct accacaaaag
    64681 ttattttttt gatgaataaa ctgcttacat gctaagtaaa ataggcgtct ggacctcctt
    64741 tttcaatccg tgcttgttca taaaattctg caactgacac attcacataa acaatgaccc
    64801 acaaaagacc gatgaacaaa gcgattgctc ctagcaaata ccagccgata aaagacagct
    64861 gcaacaaaat atacgtacca attctatctt tcaataaaaa ccagccatat ttcaaacatt
    64921 gaataaccga caaatcagga tagtcgaact ttgtccatgc agcaaattgg aataaaccgc
    64981 caacaatact catgatgagt gctgaaacaa aaatcatccc tatcatcgat aaaacaaagc
    65041 tgatatcaag aaaatcttct ggcatgacac ccgtaggtac cgcatttgaa ctgaaaagca
    65101 gctgcatata agtactcact ccgctgatta aaaacatggg cagaaagatt aaactgttga
    65161 gtagccagtt gatgactgaa ttgatcaaat tgatgccaag tatcgaacca aaatactttc
    65221 tttggaaaac tgaaaataaa aggttacttt ttggtctgcc accccgtaca actactagcg
    65281 caatgtaaaa caatgcatag ttgaatgcga ataaaagtaa attatcgact agaaaactca
    65341 ataagtgctg ctgcatgctt tcttccggaa aaggactgaa accgtcaaaa aagttctgga
    65401 tgacgctcgt aaatattata gataagaaaa caagccaagt attgattccc cattgatttt
    65461 ccaaagaaac tcgtgctttt ttccgatatt cagaaatagg tattctatta ttcattattc
    65521 ataactccga attttttcaa ctgtttcact atcaagccgt ttcactaatt ctgtgactag
    65581 tttcactgta ttcaaataat catcttcatg aatcactgat gtatgggaat gcagataacg
    65641 aacaggaacg gtaatggcta cagacggaac accatctctt gtcaaatgca tttgtcctgc
    65701 atcagttcct ccgccagaaa tcactgtata ttggaatgga atatccattt cctctgctac
    65761 atcaataaca aaattcaata attttttatg cgggatcata gatgcatcaa aaatcaaaat
    65821 ctgtgggcct tttcctaaaa tcgaatctgc ttcttttggt gtcattcctg gagtgtctcc
    65881 tgctgtacca gtatctaaag caaaagcaat atcgggattt acaaggtgtg tacttgttcg
    65941 agcacctcgc aagcctactt cttcttgcac atcgcttcct gcgaataaaa catttgggtg
    66001 tgcttcttta gatagattct ctaatactcg cagagaaaca gctgtcccga tacgattatc
    66061 ccatgctttt gccagtaaat atttactgcc attcattcgt ttgtattcaa tatatggagt
    66121 gaccatatct ccaggacgta tgccccactc tttggcttct tcttggcttg atgcgccaat
    66181 atcaatgaac atatccttta tttcataagg tttatttctt acttgaggtg ttaaaacatg
    66241 tggtggtttg gaaccaatca caccgtggac gattttccct tcacgtgttt tgatttcaac
    66301 ttgctgagca agcatgactt gcccccacca acctccaaga gtttggaatt ccaagaatcc
    66361 tttttcggtt atttttgtta ccataaaacc aacttcgtcc atatgtccag aaataaagac
    66421 cttggggcct ccgccagcac catgtttggc aatcacactg cctaaaccgt cataaaaaat
    66481 atcatcagcg aatggtttgg catattctct gaatacttct cttacctctt cttcatttcc
    66541 aggtactcct tttgcagaag ttaaatcaat aagtagctgt tcttcttttg tatccaaatg
    66601 ttttccccca tttctatatt catattgtga ttataccatt gcttatgatt tttgttcagg
    66661 caaacttggt atttttatct tttattcaga atattcaaaa ataaagaaaa caagcgagca
    66721 acactcgcct gttttcttta ttttaattgt agtttatctg gtatttgatg ttgccaagat
    66781 ttgctaaaaa aagcatcgtc aagatgatac ttactagcag taatatgatt ttcttctaaa
    66841 aacggtctga tctgttgatc tgcagccaac cagcctttcc agcctagatg gatcgtgtct
    66901 tccataaaat agttggtacc cgcttgattg acaaaatcag ctattcgatt gaatccttgg
    66961 ctatttaatt gaaatttgat ctttttggca aatccttgta acatttcttg agatagtccg
    67021 gtataatcgc tccatttctc gttaaccggt gggatgatga acaatacttc gttatggttt
    67081 tttgctaatt gatccaagac cagctgaaaa tcagaaaatt ctggcgaaaa acgataatcc
    67141 caattttttt gtgactgttt gagctctggc tcgtgggctc ggatacgatg cgtataaaaa
    67201 tcgtttttca acccgaatgg attattcgtc gtttctcgtt ctccaatttg atttgctaaa
    67261 atggataatt ctgtttcttg gtattgtttt ggtaatcgtt ttgactcatg atcgattttt
    67321 tgctgtcgat ctttcaaccc aatattgctg aatacttcat cctctctctt cagcatgttc
    67381 cattggctgc gcagctgatt caaagattca ggtaaaggta gcttcccttt tttgatcgtt
    67441 tgcagaatcg ccgtcaacgt atcattctct tttacttttg agaaagttaa taatcttcta
    67501 gctaaatagc gatcagcagg cgttactttc ttcattgaaa acaaccagtc gtatgtttga
    67561 agttcagaat aatacgtatt aaagtaatca gtttttacac catttttaac gaaccactga
    67621 ggagaaataa taaagacgac tttcttgttt ttcatagcat ctcctgcaga acgcatcatc
    67681 atatattggc ttaacgattg tgtcccgggt gctcccagca aaaatggacg atagtttcgc
    67741 tggtattttt ctgccagaac agacggatga aatggactga ttctgcttaa ttcacttgag
    67801 ccaaaaaaag gaatatattg tttttcagat aatgcataat tttttatcgc atctcctttc
    67861 aacacgttca ctgacatgga agaagaggca cgtctaatcg tttctggatt agagatatct
    67921 acttgatagg aggaggtaaa aaacacaaac agtaagccaa cagctaaaac aaccgggccg
    67981 aaaatagcaa aaagtttctt tttcatactc aacccttcaa tgcagttgct tgttgaatga
    68041 ttttattcgg tgtgctccaa tcctctcgct cgaattcaga tacagggact tggatatcca
    68101 gctctccgtc tagctcgact aataattgaa cagatgctaa agaatcaagc aacccttcat
    68161 caaatagatc aatatcacga ttttttctta cttcatctgt tcctgttatt tcttctaaga
    68221 ttgataaaat ttgttcttcc attttccttt tctcctttgt tatataaatt aatatgtcac
    68281 tattcgttag ctaaaaaaaa gtttatctaa aaatcctgaa aaaatcagga agctaaaaca
    68341 tactgcttga aatgtcaaaa atacggctaa gccatgcgta aatttgttag aaggcaactg
    68401 ctctttatgc ttcttcttaa atcggatcca tgcatctgtc agacagatca gacaagcatg
    68461 atacagtcca tatacgatgt agtaccacgt caatccatgc catataccca ttagaagaaa
    68521 caaagcaaaa taaccgatat ttgacattac gatcttgctt ttaaaaaatt ttttcttcat
    68581 catgaagaac atcaatcgca tatatacata atcacggaac caaaaggaca gcgtcatatg
    68641 ccaacgattc cagaattctt tgatattcca tgataaaaaa ggtttattga aattgattgg
    68701 tgtctgatat cccatcatgt agcttgtacc gactgcaaat aagctatagc cagcaaaatc
    68761 aaaaaacaaa tacatactgt acacgtacat ataacctact aatgcccatg aaataccacc
    68821 atgctgtaag gcaatgcgtc ccactacagg aagcagtact tgaccaaaat aataaccgat
    68881 aatgaattta tataaaaaac cgacaaaaat attttggacg ccttttccca aaagatcaac
    68941 atatttatca cgaacaggcg gatggagctg atctttttca aatctcctat agcgatcgat
    69001 tggtccagaa gagattgttg gaaagaacag cagaaactgg atataacgaa atggcttata
    69061 tgttttgatc atgccatctc ttatttccat gatcatttgt acagatttaa aggttaaata
    69121 agagattcct aaaaaaccaa gtaacgatgc ttttccatgt tcaaaaaaag gagtcacttt
    69181 cgttaaaaac agtggaatta tcgctaaaat aacggcggca aaaaaccatc ctgtctgatt
    69241 tttcctttgc cgataaacaa aatagcccca tacaagtatc gtctgccaca aaacataccc
    69301 aatcagcgcc gctccctgtt gccaataatt acctccaaag ctgacaaata aaaagaaaag
    69361 tgtcactgct gattgataaa ctggtaatct tttttcccat atcaataaag atagaacgat
    69421 cggtacaagc gcaatggcta aaagaaaaaa ataaaacggc tctgcataag ggatcatatg
    69481 aggtaacatc attcaggatt cacctcagct gttaattttt ttcgatcgat ttttccatta
    69541 actgtctgag gcagcagatc gacataatgg aacttctgag gaatcatata atccattaca
    69601 acttctagta attgttcttt gatagattta gtcaactgaa aatccggctg tttcgttttg
    69661 ttttctaata cgacaaaagc aaccagctgc tgtacttttg ttccttggta ttttggtacg
    69721 acgacagctt gtttgattcg gttgtcttgg agcagataat gttcgatatc cccgagttca
    69781 atccggtatc catgtaattt gacctgctga tccatacgtc cttcataaaa taaaagccca
    69841 tattcatcta gtctacctgc atcccctgta tggtaacttg ctaagtcatt ttgacaaaag
    69901 aacgcagcag ctgtcttttc gggattgttc aggtaacctt ttgatacgct tggtcctgca
    69961 ataatgattt cacccgtttc tccttttgaa acaggtttac cttcttggac aatagaaact
    70021 ttcgtgtctt tttttacgta gccaatcggt agtcggtcat aactatctag tacatgctgg
    70081 tcaatctgaa tacttgaaat agctacagtt gcttctgttg gaccgtaagt attatatatc
    70141 cgtgcatttg ggaatcgatc aagtagactt tctgcagttt ttttcgtcaa ttcttctccg
    70201 caaaataaaa acatgtccaa ttccggcaca ttttctccat tgaatgtagg ttccatcaag
    70261 caaatatcca taaatgatgg agtagaaacc cacacattca acttcaaggc tggcaatgtc
    70321 gcgaataatt gacgaaagtc ttgaacaact gctttattta acggcttcag cattccgcca
    70381 gaaactaatg caggataaat agaaaatacc gataaatcaa aagaaaatgg cgcttgggct
    70441 aagaaatgca taccaggctt gatcccaaag tcttccatcg tccattgaac aaagctgact
    70501 agattatcat gactgatttg tacgcctttt ggttctccag tagtaccaga agtaaaaata
    70561 atataaaaat tttctgtacc ttttacgcta tttctgggat aaaatcctac tggtatcttc
    70621 ttgatttctt gaaattcttt ttttgttatg acaggaaccg aaggaatatc ttctatccag
    70681 tccccgatac tgatgaccat agatggttta gccacccgaa agatcgatag gatacgctcc
    70741 ttgggtgtat gctcttcaat cggcaaatag gcatggccag atttgacaac ccctagaaat
    70801 gagacaatca tttcaaactc caaattgcca aaaacgacaa ttggtccatc gccttctacc
    70861 tttttttcta aataataagc aagtgcgtct gatgcttgtt tcaattcacc aaaagtatgc
    70921 gtctcatccg cctgataagc aactcgatca ggttcattta ttccccaatc atcgattgct
    70981 tcaataatcg ttttgatttc catactcttc ctcctaaaat tcgttataga taaaagttcc
    71041 tccttgaata tttttatagt gatacagata aatcaggaac agcagtactg cactataaaa
    71101 aattgttcga atgatgaatt ttccccaata attcaatttt ggattagaac gccatttgtt
    71161 cattggattc cctcctcata taacctcaca caaagtgtaa ctaattttga caaaaagaaa
    71221 catgtgtcta gcttacagaa accgtttttt tactaacagt tttgtcacat agcttttata
    71281 aaaatagcac atcaaatcac tgcttttttc tttataattt ctcgtacttt taaa
//
LOCUS       DAXQKX010000006        68807 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.006, whole genome shotgun sequence.
ACCESSION   DAXQKX010000006 DAXQKX010000000
VERSION     DAXQKX010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 68807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68807
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.006"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(112..627)
                     /locus_tag="ACF3MF_000442"
     CDS             complement(112..627)
                     /locus_tag="ACF3MF_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HFE3926471.1"
                     /translation="MVVVMVKVFDIIKFSDFRGYTAVALDNETLFSIGIEFHIKQINQ
                     GFSHNKYTMRGLHYQSGEHAQGKIVMCLHGEIMNIALDIRQGSSTYGCVYVNTLSESN
                     GKCAYIPRGYAHGYLTMEDNTLVQWCVDNDFNSNAAKCISYESVDIEWPVSRQCFVIS
                     EKDKNVERLSF"
     gene            complement(809..1420)
                     /locus_tag="ACF3MF_000443"
     CDS             complement(809..1420)
                     /locus_tag="ACF3MF_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFE3926472.1"
                     /translation="MIDIISAITVNVLTALYQPFLFAVLTAYLFMYWYLFIVDNSRDP
                     KNLKDSVLIWLRYFKASSKFRRLFFLAFYFTLILFKTLLNRNMWMNPLSNVIGQWSLY
                     IIDNATGESRLTTECVENTMLFIPFCMLLLWWRDIKCDIIRTIYVGIKYVFLFSLSIE
                     FTQLFFRLGTFQLSDLFYNTLGGLIGALLYWLFYRLNKYIDLK"
     gene            complement(1446..2897)
                     /locus_tag="ACF3MF_000444"
     CDS             complement(1446..2897)
                     /locus_tag="ACF3MF_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFE3926473.1"
                     /translation="MTSNNLIVKTLSRYKNTPLPVKAALWFMVCGFLQRGVSMITTPI
                     FTRVLSTEQYGLYSTYLSWESLLLMITSLSLFKAMMNLYVKYDNQEHILSTVSGLTLV
                     LTIFWFVIAIFIKDILAEILGLTPVLVVCMFSYFIFQAEIQCWSLHKRYIYDYKTLLV
                     ATLAVTVGSSVVGCLAVLFISPTAEARALMNVLVTGVVGVAVYISVFRRCKDFKDNEV
                     WNFAVVFCVSLMPHYLSEFILNGSDKIMINYLCGSSDVAIYSVAYSIGALINLVTNSV
                     NSTFAPYQYQKIKSGEYDLLSKRANEVLGLVAAMLFALMLFSKEIVLIFGGQKYIDSV
                     NLIVPICIGIYFNYMFQLFARVQEYFEKKLTVVIPSVLCAIMNIVLNYVFIKLYGYQA
                     VAYTTVFSYMFFCVIHYIFYRKVCKELLDGKNIYDVRGILLISAITIAGGILISIINK
                     FDFIKYLIIAIACVAAIIFRKRLLLLVRRIMSK"
     gene            complement(2921..3652)
                     /locus_tag="ACF3MF_000445"
     CDS             complement(2921..3652)
                     /locus_tag="ACF3MF_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFE3926474.1"
                     /translation="MEKKMTVIITMAGLGSRFRKIGYAVPKYMINAKGRTLFDWAMDS
                     LVGYNKNVDKYIFVVRQEDNASAFIKEHCAYFGIENVEVIEIDYMTDGQATTCMLAIP
                     YCNQDNEIMVYNIDTYVESNEMKYEDICGDGHIPCFHADGDHWSFAKLNDRNEVIEVR
                     EKVRISDNCTLGAYYFSSAKLYKALYEEYYADSSNMEKNEKYIAPLYNFMIKKGLKVT
                     ISIVDAKKVHVLGTPEELNVFLNQE"
     gene            complement(3670..4065)
                     /locus_tag="ACF3MF_000446"
     CDS             complement(3670..4065)
                     /locus_tag="ACF3MF_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HFE3926475.1"
                     /translation="MYSEYSFVFDIDGTLCPIKKKDERYEDLVPYENMVEKLRFYKEN
                     GAKITLFTSRNVNSYKGNLGMINANTAKVLLAWLDKWDIPYDEILYGKPWPGHKGFYV
                     DDRTVRPDEFLRCSVDELNEICNSSKKRF"
     gene            complement(4167..5804)
                     /locus_tag="ACF3MF_000447"
     CDS             complement(4167..5804)
                     /locus_tag="ACF3MF_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HFE3926476.1"
                     /translation="MKVLIPAAKVVEKELQSIGMLPAIIYPINKKIVFDYLYNQYNAI
                     CDSLDIICYEKADKVHRRLKNYHDSRIHICDLPELGDLGQTVYFGLSDEDEPVLINFA
                     DTIVMESMSDIEMDTFYYSEDFVSSTWTYFKINEGIITDIHDKEEAYVSDKREKLFIG
                     VFMFSSSKLLKSCLREAVESRKQGGINSFYRALQLYSERCPLKAVRTEKWFDIGHIDK
                     YYNTKLEVKAREFNHISIDKDRGILKKTSDDKDKFIGEIKWYLKLPADIEYVRPRIFD
                     YSTSYVAPYVDMEYYAYHTVHELYLYGDLKYNQWHDLFSRIKFICSDFKRYTLKDEKI
                     RESLEDMYLRKTMQRFQKLSEDKRFSAFFEKQIQINGRKFISLTGVIELLKNLIPSML
                     YDVNEFCIIHGDLCFANMMVDSNCSFVKVIDPRGKFGKYDIYGDSRYELAKLFHSLDG
                     KYDYIIKDLFTVEYDTECAVIDYTINTRVRDYDLFELFKSVFSDEIKDDFDKIVLIEA
                     LLFLSMIPLHGESFDHQIVMLATGMELLARVSNKVIL"
     gene            complement(5839..7173)
                     /gene="gmhB"
                     /locus_tag="ACF3MF_000448"
     CDS             complement(5839..7173)
                     /gene="gmhB"
                     /locus_tag="ACF3MF_000448"
                     /EC_number="3.1.3.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-glycero-beta-D-manno-heptose 1,7-bisphosphate
                     7-phosphatase"
                     /protein_id="HFE3926477.1"
                     /translation="MKTVIMAGGRGSRISELFPDIPKPMIPIDGIPVLERELCSLRDQ
                     GFNDIILTVSYLHEKIEEHFGDGSKLGIKIKYFIEKTPLGNAGALYFLLDELGDEPFL
                     LLNADAVFDVDFRQMIRFHVENNADVTLFTHPNSHPYDSGLIISDDNKKVLQWLAKED
                     QRPEYYKNRVNAGLHVINPKVLRENPLMEIVNKSIVEGGGLPYKIDLDRMILKPLANT
                     GRMYCYDSPEYVKDMGTPDRYRAVIKDFQKGIIVGKNLSNPQKAIFLDRDGTINKYVG
                     FLRNAEEFELIDGVSEAIKIINSLGFLCIVITNQPVIARGEVTVDELNSIHNKLETML
                     GHAGGFLNGIYYCPHHPHKGYAGEVIELKIDCNCRKPKPGLLLEASKDFNINLSQSFM
                     VGDSESDVIAGKNAGCKTVLITEDITLPANYGQDYSVCSLLEFVKNHLCTMQ"
     gene            complement(7215..8324)
                     /locus_tag="ACF3MF_000449"
     CDS             complement(7215..8324)
                     /locus_tag="ACF3MF_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WavE lipopolysaccharide synthesis family
                     protein"
                     /protein_id="HFE3926478.1"
                     /translation="MNKKEILYNILKKYENLPYVFRNMFGHNISKLVSWKLTADCATV
                     EENSEVYAAFQLRSKDMSDVPVMGLVNCCKDVAIVMQGPLCLKDDFSYNTLAYYKKCY
                     PNALIILSTWKDEDIKALKRIEDLGVIVICSEKPEKPGHLNINYQVGNTLPGIVRAKQ
                     LGAKYVCKTRTDQRIYHPNAMAFFCSLLEQYPVNNEDDWKLIQNQRLLLLSMPYGDMF
                     FPYCLSDFLYFGDVDDMINLFSIPSDVREKGAVSRGVSRREISENNLAPEVQLLRSYI
                     SRMGGNEECSIRAYWEFVKNHVITINKNQIDLYWHKYVGRYSNNTIYGTYYIDDSQDA
                     LHCYNFDFINWLNLYTGKYEYKAEYEKYMDFVWEE"
     gene            complement(8349..9584)
                     /locus_tag="ACF3MF_000450"
     CDS             complement(8349..9584)
                     /locus_tag="ACF3MF_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926479.1"
                     /translation="MQISKWKIIQFLMVFLMIISSSILKPLGGWLGETMNVRLVTVIL
                     AIVCLLIASLPAFRKNRYLNFCTLLICVVIIAAYIYSDKTIWVKSRESMSLYYVLLAY
                     PLFCTLINQAWNLDSMLNTICGVTFLSYILRTSISLIQKFSGVLLYENIYRECAPENW
                     YRGGFLRINPPCFTIIIIPIALYMIERQVVARRKVKYYLLIASALAYSAVIHGSRSVL
                     VYQIIVLGCYILFKKGSSKRKIAMWVLAGLLVVIFINSTMFSTFVETFTNSTGEYAGS
                     AESRFASVWFFIPKFLQSPLFGTGILTGEEFTFILPGGVRGHLSDIGFFYTITQYGVG
                     ILIFDILFIIKGFKTALLASKVGMTGYQYLAFGITLNVLLTGINIDWFYPIFTPAIPV
                     CLAVIEYIYQECRSVANIE"
     gene            complement(9615..10721)
                     /locus_tag="ACF3MF_000451"
     CDS             complement(9615..10721)
                     /locus_tag="ACF3MF_000451"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFE3926480.1"
                     /translation="MKVLMCESQMPENWYSFDLSKELNQYVDLTLLCKRDVPPLDPKI
                     KSKHILYHKSTNKVFSALVFLKSLFLIWKEIRFGDYDIVHLQLMKSLKYEGGLYVLCK
                     RHYKKLIMTVHNVLPHEVREKDRQEHFNIYSNCDGFIVHNRVTEQHLYAEFPELNAKS
                     YVCPHAIYGDVKHISRAYDKDKFEFILFGQIRPYKGIDVLLNAITELPMDVRKKVHFT
                     IAGQQHPKQDSTDYKKMIEDLKVSDCVLYKPERISDEEMDSMFRNADAAIFPYKEIYG
                     SGALLMAYTYCLPTIVSNVPAFMEETEEGKIGLLFENLNSKSLADTIVKYVNLSPAEK
                     SKIEDDIYELVNRKYTWAASAKLTYEAYKQILNE"
     gene            complement(10732..11505)
                     /locus_tag="ACF3MF_000452"
     CDS             complement(10732..11505)
                     /locus_tag="ACF3MF_000452"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family A protein"
                     /protein_id="HFE3926481.1"
                     /translation="MLYFVIPLMSAKAANNWEMVSTLFNRTLWSCYNQTDPDFKIIVA
                     CHEIPKLTHEYDDRVEFIQVSEKDAPIPTNQDEKMIDKGYKTHALAMRLRELGGGFAM
                     MVDADDLVSSHLAEYVNSHPQENGFYVKTGYVYFVGDDYMKVLPKFSSGSACIVKYAV
                     EDLPEAYPEVMTANCDDNPWIIRKRHGGVVPACEEQGRPLKPLPFKAAVYVLGTGDNH
                     SLYGKTTKYQTKMREILEMFIAKRKIKGKLKAEFSVDWL"
     gene            complement(11519..11974)
                     /locus_tag="ACF3MF_000453"
     CDS             complement(11519..11974)
                     /locus_tag="ACF3MF_000453"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HFE3926482.1"
                     /translation="MNAYKLYKVERWFYLHKMEFFAKIVKALIYVLHNSSISYQTEIG
                     DNCKFLYGGIGCVIGKDTKIGNHVIIGTNVLTGGRSNKPGMPTIGNNVYIATGAKILG
                     NITIGDNVIVGANAVVINDVEPNCSVGGVPARVLKKDIDVNDYCSLNRY"
     gene            complement(12396..13502)
                     /locus_tag="ACF3MF_000454"
     CDS             complement(12396..13502)
                     /locus_tag="ACF3MF_000454"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFE3926483.1"
                     /translation="MKILIVVTMTNNFGKKGSYNSQEIGLARGLAELGHEVIVYKSVK
                     SDEEVGTEQLSNTAMIHYIKCRYVGSNGFLSTKNFDKNADVLIQFADLQLSVPHVYSW
                     TVKNGIKYIPYNGITRSQSGNKYIKTIIEILAHRNYKIYKKNGCVAKNDRVSEKLVQL
                     GVNKVKLAPVCVDFEQLHKNYEAIDFTTLREKWNIPRNVRVILYVGRFEKDKRPLDMI
                     SLFNKLDEHNYLLMVGTGALLEQTKQQINLLGLQNRVKIIERIPNKDIWELYCLSDVF
                     VNLNYTEIWGMVLLEAMYYRLGIIAVNAPGPQNIILDNRYGMLAKSDDEILTFLKDGR
                     FTNDIIDAAYQRVTTEFRWSKSGEIMLSMLEGDK"
     gene            complement(13520..14281)
                     /locus_tag="ACF3MF_000455"
     CDS             complement(13520..14281)
                     /locus_tag="ACF3MF_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HFE3926484.1"
                     /translation="MEKNMYKRKRDFTVCGIVGVCATTKNEFVREVFSMPTSPVSATV
                     DLVGVPAIISAKENPKIAEMYSQATMAAIDGMPIVKIGRRKGFTCERCAAPDIMGMVF
                     EEGVRQGKTHYFYGGKDNEVLNKLRANLERDYPGIKIVGMYSPPFRPLNEEEDSKICE
                     EINNLNPDFLWVGIGAPKQEMWMWEHQKKIHNTVMFGVGAGFNFFAGTLEKAPEWMEK
                     ASLEWLFRLVKEPRRLWRRYILGGIKYIYYTIESK"
     gene            complement(14357..15355)
                     /locus_tag="ACF3MF_000456"
     CDS             complement(14357..15355)
                     /locus_tag="ACF3MF_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HFE3926485.1"
                     /translation="MKKTIMVTGGCGMIGSNLVKRLVKEGCWDVYVADNLWRGKLEYL
                     NDEDGHPVIDLDTHFFNADLTDYEQAKKVIGTTEYVVHLADVVAGIDYVFKNQGELFR
                     INNLINSNVFDCCRKAGKEKIKGVIYVGTVCSFPLTRQNTLNPEPLREEELFPALPES
                     AYGWSKLMGQLEMGYLEKETGIPCCILMLHNVYGTPTDFGERSQVIPALIRKAINNPE
                     EPFNVWGSGEQGRAFIHVNDIVNALVLALDKGWGHGHIQIGPSHCTSIKEIAYKIIEI
                     SGKDIKPFFDTSKPEGDKARCADYSKAKEILDWEPTVSLEEGLRESYNWIEKQIKG"
     gene            complement(15374..16027)
                     /locus_tag="ACF3MF_000457"
     CDS             complement(15374..16027)
                     /locus_tag="ACF3MF_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFE3926486.1"
                     /translation="MLAEKLNKHIDLLIKRYPTLETIKQDIIDGYLIMEECYLNGGKL
                     LVAGNGGSAADSEHIAGELMKRFKTPRPVSKEFADKLVAIDPVRGPELAKNLECGLTA
                     IPLVAHEALSTAYINDVDGLGVFAQQLFGFGRSGDVFLGISTSGNSKNIMSATVVARA
                     LGIKVIGLTGAKGGELATVADVCVKAPEVETYMIQEYHLPIYHCWCLMLEDKFFGNE"
     gene            complement(16037..17047)
                     /locus_tag="ACF3MF_000458"
     CDS             complement(16037..17047)
                     /locus_tag="ACF3MF_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HFE3926487.1"
                     /translation="MIITKTPFRMSFFGGGTDMEDYFKENGGAVLSTTFDKYCYVNVR
                     HLPRFFDYSAELSYSRTERVTSIEDIEHPAIRNAMKMLDMHEIRLTYEADLPARSGLG
                     TSSSFAVGMLNAFYALEGKYADKKKLADEAIYLERVLCNEAGGWQDQIAASYGGFNRI
                     NFNVDGYEVLPVIISPERKKQLNNNLMMFFTGFTRFSSDVQKANNVSGTEDKRVRLKK
                     MYELVDEAEAILTDKNRNLDDFGRQLDVTWRLKKGTGGAISTGSIDELYEKGMAAGAL
                     GGKLLGAGGGGFLVFYVQPEKQDAVRWAMRDLMYIPFEFENGGTRVIHYTPETYIEKQ
                     NG"
     gene            complement(17066..18316)
                     /locus_tag="ACF3MF_000459"
     CDS             complement(17066..18316)
                     /locus_tag="ACF3MF_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HFE3926488.1"
                     /translation="MKKQYNIAVAGTGYVGLSIATLLAQHHKVTAVDIIPEKVELINN
                     RKSPIQDDYIEKYLAEKELNLTATLDAKAAYQSADFVVIAAPTNYNSRTQHFDTSAVE
                     AVIRLVMEVNPDAIMVIKSTIPVGYTASVRVKTGSKNIIFSPEFLRESKALYDNLYPS
                     RIIVGTDMDDERLVEDAHTFATLLQEGAIKENVDTLFMGFTEAEAVKLFANTYLALRV
                     SYFNELDTYAEMKGLNTQQIINGVCLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYA
                     DVPENLIEAIVESNRTRKDFIADRVLQMAGYYNYAEANQYDAGKEKPVVIGVYRLTMK
                     SNSDNFRQSSIQGVMKRVKAKGATVVIYEPTLKDGETFFGSKVVNDLEQFKAMCDSVI
                     ANRYDACLDDIKEKVYTRDIFQRD"
     gene            complement(18823..19103)
                     /locus_tag="ACF3MF_000460"
                     /pseudo
     CDS             complement(18823..19103)
                     /locus_tag="ACF3MF_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003697748.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
     gene            complement(19662..19772)
                     /locus_tag="ACF3MF_000461"
     CDS             complement(19662..19772)
                     /locus_tag="ACF3MF_000461"
                     /inference="COORDINATES: protein motif:HMM:NF020874.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1972 domain-containing protein"
                     /protein_id="HFE3926489.1"
                     /translation="MNPNGYEWLRAKGSYPVPKYCNYSETLMEWYQLIIT"
     gene            complement(20178..20867)
                     /locus_tag="ACF3MF_000462"
     CDS             complement(20178..20867)
                     /locus_tag="ACF3MF_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFE3926490.1"
                     /translation="MESEDLLSRISEVHPNQVWLDKEKVEKRYIYLFFKRMIDIVGSI
                     IGLILASPLMFYVAYRIRKEEPGSPIFFCHTRVGKNGKTFKMYKFRSMCLDAEEKLEE
                     LLDQNEIEGAMFKMKEDPRVTKIGKIIRAKSIDELPQLWNVLKGDMSLIGPRPPLERE
                     VAEYTRYDLQRLYVKPGCSGLWQVSDRNNVSFHKMVELDLEYISHRSLMYDLRLILKT
                     FYVIVKPNGAY"
     gene            complement(20912..21676)
                     /locus_tag="ACF3MF_000463"
     CDS             complement(20912..21676)
                     /locus_tag="ACF3MF_000463"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsB/CapC family capsule biosynthesis tyrosine
                     phosphatase"
                     /protein_id="HFE3926491.1"
                     /translation="MIDLHCHILPGIDDGAENIDASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIDRDEILFTDLD
                     DTYLLIEFPTLEVPLYAEQLFFELLQLGKTPVIVHPERNAHFRKDPNHMLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKMMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            complement(21704..22402)
                     /locus_tag="ACF3MF_000464"
     CDS             complement(21704..22402)
                     /locus_tag="ACF3MF_000464"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004713 - protein tyrosine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0004715 - non-membrane spanning protein
                     tyrosine kinase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HFE3926492.1"
                     /translation="MARTQKQKAAQTHAVSLVTLTTPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVIYKTFKLNNAS
                     GLSTVLSSSGSVADEIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENMSRKESLTKAKELLDMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            complement(22415..23194)
                     /locus_tag="ACF3MF_000465"
     CDS             complement(22415..23194)
                     /locus_tag="ACF3MF_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzz/FepE/Etk N-terminal domain-containing
                     protein"
                     /protein_id="HFE3926493.1"
                     /translation="MEETISLKEIFETLRKHVITILISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQATSTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGPAPTQPKATNDKTAPSRRSRSRV"
     gene            complement(23210..24154)
                     /locus_tag="ACF3MF_000466"
     CDS             complement(23210..24154)
                     /locus_tag="ACF3MF_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFE3926494.1"
                     /translation="MAKRRRRSRGKKIFLIILAILVVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGHDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFTIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYRDAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            complement(24195..24974)
                     /locus_tag="ACF3MF_000467"
     CDS             complement(24195..24974)
                     /locus_tag="ACF3MF_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926495.1"
                     /translation="MEKPFVKLLATVAVGTGAIVICLFGYHLNNQRQHHQRINYAESA
                     ITNQKDTVTSLSKEVDKLYSTKEKIFLNPEITEETVSNLSHKLSSIKLSADDYDIKES
                     ELPKEAAAIQEEKKAVLTQLEDAESKLKIQTAVNKLFTKNVSNWQQAVDDVIIKEKLA
                     SADVAHVRENMSFFKDSAWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSLIEQIRNEKIRAAYASKAETVAQQMGYSNTSY"
     gene            complement(25358..27433)
                     /gene="glyS"
                     /locus_tag="ACF3MF_000468"
     CDS             complement(25358..27433)
                     /gene="glyS"
                     /locus_tag="ACF3MF_000468"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HFE3926496.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEIIPFEILDVKTDRVSRGHRFLGEDVTFTHAKEYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKNHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAQLEKQSEVDPELFENDAEKELHKAVEA
                     MKASFADQTIHENYDQLVALRPLIENYFDQTMVMADEPAVRKNRLTQLSQITAMALSL
                     ASLDQIITK"
     gene            complement(27435..28352)
                     /gene="glyQ"
                     /locus_tag="ACF3MF_000469"
     CDS             complement(27435..28352)
                     /gene="glyQ"
                     /locus_tag="ACF3MF_000469"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HFE3926497.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENVKEAE"
     gene            complement(28736..29548)
                     /gene="recO"
                     /locus_tag="ACF3MF_000470"
     CDS             complement(28736..29548)
                     /gene="recO"
                     /locus_tag="ACF3MF_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HFE3926498.1"
                     /translation="MSQLVESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            complement(29691..30590)
                     /gene="era"
                     /locus_tag="ACF3MF_000471"
     CDS             complement(29691..30590)
                     /gene="era"
                     /locus_tag="ACF3MF_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HFE3926499.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(30605..31000)
                     /locus_tag="ACF3MF_000472"
     CDS             complement(30605..31000)
                     /locus_tag="ACF3MF_000472"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFE3926500.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            complement(30984..31460)
                     /gene="ybeY"
                     /locus_tag="ACF3MF_000473"
     CDS             complement(30984..31460)
                     /gene="ybeY"
                     /locus_tag="ACF3MF_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HFE3926501.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(31477..33669)
                     /locus_tag="ACF3MF_000474"
     CDS             complement(31477..33669)
                     /locus_tag="ACF3MF_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing metalloprotein"
                     /protein_id="HFE3926502.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIICGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQKRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDAINKSYDEKIDKAKEDENIPKPTTEERIAALKKNFENVNAENVVFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEEQIQYLNVTPAQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEVQEE"
     gene            complement(33693..34664)
                     /locus_tag="ACF3MF_000475"
     CDS             complement(33693..34664)
                     /locus_tag="ACF3MF_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HFE3926503.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            35370..36749
                     /gene="brnQ"
                     /locus_tag="ACF3MF_000476"
     CDS             35370..36749
                     /gene="brnQ"
                     /locus_tag="ACF3MF_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFE3926504.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGSNWI
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYDSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFQPMGNLNQSAADSYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKSPFVYQVTMFFSAVPAVLDM
                     LANSPALVSQQTVVASLLGFYHHYVPFAALGLGWVVPTLLGYAGSLLFYYVYRVSGYK
                     QEASELPEE"
     gene            complement(36903..37349)
                     /locus_tag="ACF3MF_000477"
     CDS             complement(36903..37349)
                     /locus_tag="ACF3MF_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HFE3926505.1"
                     /translation="MSLLSRLNDDMKAAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(37376..37552)
                     /gene="rpsU"
                     /locus_tag="ACF3MF_000478"
     CDS             complement(37376..37552)
                     /gene="rpsU"
                     /locus_tag="ACF3MF_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HFE3926506.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            complement(37714..38142)
                     /locus_tag="ACF3MF_000479"
     CDS             complement(37714..38142)
                     /locus_tag="ACF3MF_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFE3926507.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGKIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            38234..39094
                     /locus_tag="ACF3MF_000480"
     CDS             38234..39094
                     /locus_tag="ACF3MF_000480"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, water dikinase regulatory protein"
                     /protein_id="HFE3926508.1"
                     /translation="MTSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLRQALQDALEEKALVLHTLINQELIEITRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEKSD"
     gene            complement(39186..39536)
                     /locus_tag="ACF3MF_000481"
     CDS             complement(39186..39536)
                     /locus_tag="ACF3MF_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HFE3926509.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKSKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(39551..41278)
                     /locus_tag="ACF3MF_000482"
     CDS             complement(39551..41278)
                     /locus_tag="ACF3MF_000482"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HFE3926510.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAKHSGLITIIGEEVDAAYLEEIKAV
                     TIDRELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPDGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EENHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYFAEKTISVTMSGQEGSAKISALMEKFRKEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGSSTEDAAEKVASYE
                     AIIKKMTEE"
     gene            complement(41492..42418)
                     /gene="trxB"
                     /locus_tag="ACF3MF_000483"
     CDS             complement(41492..42418)
                     /gene="trxB"
                     /locus_tag="ACF3MF_000483"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HFE3926511.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNMPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            complement(42563..43996)
                     /locus_tag="ACF3MF_000484"
     CDS             complement(42563..43996)
                     /locus_tag="ACF3MF_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFE3926512.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGKDRFPV
                     ITGKKKMFEFDEDHFYPAKIAIDMYHRYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNEAGLKFYEDAFKECQKHGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            complement(43996..45399)
                     /locus_tag="ACF3MF_000485"
     CDS             complement(43996..45399)
                     /locus_tag="ACF3MF_000485"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008706 - 6-phospho-beta-glucosidase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFE3926513.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEENGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKEEGIEVQ
                     DELARELSGNTHIMEEV"
     gene            45630..46532
                     /locus_tag="ACF3MF_000486"
     CDS             45630..46532
                     /locus_tag="ACF3MF_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFE3926514.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQAIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIHDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSAMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVE"
     gene            complement(46572..48458)
                     /locus_tag="ACF3MF_000487"
                     /pseudo
     CDS             complement(46572..48458)
                     /locus_tag="ACF3MF_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
     gene            complement(48551..49402)
                     /gene="licT"
                     /locus_tag="ACF3MF_000488"
     CDS             complement(48551..49402)
                     /gene="licT"
                     /locus_tag="ACF3MF_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HFE3926515.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTITIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELFQVIQKKYKDTFGCVEKIADFLAETFNYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            complement(49728..51512)
                     /locus_tag="ACF3MF_000489"
     CDS             complement(49728..51512)
                     /locus_tag="ACF3MF_000489"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3926516.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYIRVKLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFLAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     VLTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSIFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQMITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGI"
     gene            complement(51512..53263)
                     /locus_tag="ACF3MF_000490"
     CDS             complement(51512..53263)
                     /locus_tag="ACF3MF_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter transmembrane domain-containing
                     protein"
                     /protein_id="HFE3926517.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGVFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIIFGWIFLLIIAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     QMWEKQQLEAKIEGGEA"
     gene            complement(53405..53629)
                     /locus_tag="ACF3MF_000491"
     CDS             complement(53405..53629)
                     /locus_tag="ACF3MF_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HFE3926518.1"
                     /translation="MLSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            53880..55466
                     /locus_tag="ACF3MF_000492"
     CDS             53880..55466
                     /locus_tag="ACF3MF_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HFE3926519.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVSQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQNEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHAALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQLLQETVEEIE"
     gene            complement(55532..57307)
                     /locus_tag="ACF3MF_000493"
     CDS             complement(55532..57307)
                     /locus_tag="ACF3MF_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HFE3926520.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(57520..58422)
                     /locus_tag="ACF3MF_000494"
     CDS             complement(57520..58422)
                     /locus_tag="ACF3MF_000494"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HFE3926521.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAEKGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQTFDPEVFPELLAEEVIL"
     gene            58701..61046
                     /locus_tag="ACF3MF_000495"
     CDS             58701..61046
                     /locus_tag="ACF3MF_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HFE3926522.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAK
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            complement(61383..62384)
                     /gene="ccpA"
                     /locus_tag="ACF3MF_000496"
     CDS             complement(61383..62384)
                     /gene="ccpA"
                     /locus_tag="ACF3MF_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HFE3926523.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            62594..63700
                     /locus_tag="ACF3MF_000497"
     CDS             62594..63700
                     /locus_tag="ACF3MF_000497"
                     /EC_number="3.4.11.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HFE3926524.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLTSIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            complement(63759..64361)
                     /locus_tag="ACF3MF_000498"
     CDS             complement(63759..64361)
                     /locus_tag="ACF3MF_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFE3926525.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDSKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(64364..64804)
                     /locus_tag="ACF3MF_000499"
     CDS             complement(64364..64804)
                     /locus_tag="ACF3MF_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HFE3926526.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            complement(64929..65867)
                     /gene="galU"
                     /locus_tag="ACF3MF_000500"
     CDS             complement(64929..65867)
                     /gene="galU"
                     /locus_tag="ACF3MF_000500"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFE3926527.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            complement(65882..66907)
                     /locus_tag="ACF3MF_000501"
     CDS             complement(65882..66907)
                     /locus_tag="ACF3MF_000501"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFE3926528.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGIGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            complement(66951..67781)
                     /gene="lgt"
                     /locus_tag="ACF3MF_000502"
     CDS             complement(66951..67781)
                     /gene="lgt"
                     /locus_tag="ACF3MF_000502"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HFE3926529.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            complement(67796..68734)
                     /gene="hprK"
                     /locus_tag="ACF3MF_000503"
     CDS             complement(67796..68734)
                     /gene="hprK"
                     /locus_tag="ACF3MF_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HFE3926530.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
BASE COUNT        20126 a        14661 c        11487 g        22533 t
ORIGIN      
        1 tctatatcta aatttagttt tatgtattcc tcatagaaat aaccgagcat ttgctcggtt
       61 attgttcttc ttattttcca gtatccttct tttctccaca gctcatttta atcaaaagct
      121 taatctttcc acatttttgt ctttctcact tataacgaaa cactgccgac tgaccggcca
      181 ttcaatatct acgctttcat aacttataca tttggcagca ttagaattga aatcattatc
      241 tacgcaccac tgaactagcg tattgtcctc catagtaaga tagccatgag catatccacg
      301 tgggatatac gcacatttac cattgctttc actcaatgtg ttgacataca cacatccata
      361 agtggaagat ccttgtcgaa tatcaagtgc gatattcata atttcaccat gtaggcacat
      421 cactatcttt ccttgagcat gctctccact ctgataatgt agccctcgca tagtatattt
      481 attatgacta aatccttgat ttatttgctt aatgtgaaac tcaataccaa tcgagaaaag
      541 agtctcatta tccaatgcaa cagcagtata tcctctgaaa tccgaaaact taattatatc
      601 aaacactttt accataacta ccaccatgtt atatatttta ccaatttttt aattcgctcg
      661 acctcattta aagcaataaa attccctacc tcttgaagat ataacaacaa tgttttagca
      721 aaaatagatg gcatgtaaag tattcttgat gagattacac aatcctgtct gcagaaaaat
      781 attaaccata ttaaaattca aagcagttct attttaagtc tatatactta tttaatcggt
      841 agaatagcca atatagcaaa gcaccaatta agccccctag ggtgttataa aacaaatccg
      901 atagttgaaa tgtaccaagc ctaaaaaaca gttgtgtaaa ttctatactt aatgagaata
      961 aaaacacata cttaatccca acatagatgg tgcgtataat atcacattta atgtcacgcc
     1021 accataacaa taacatgcaa aaagggataa acagcatcgt gttctccacg cattctgttg
     1081 tcaatctgct ctctcctgta gcattatcta taatatataa tgaccactgt ccaataacgt
     1141 ttgaaagcgg gttcatccac atatttcgat taagcaaggt tttaaataat atcaaagtaa
     1201 aataaaacgc aagaaaaaag agtctgcgaa atttactaga tgctttaaaa tatctcaacc
     1261 agattaatac agaatctttt aagtttttag gatctcgaga gttatcaact ataaatagat
     1321 accagtacat aaacagatac gctgttaata cggcaaataa gaacggctga tataatgctg
     1381 ttaatacatt taccgttata gcagaaataa tatctatcat tctctatctc tctatgagca
     1441 aatgtttatt tgctcataat tctccttact aaaagtagca atcgttttct aaatataatt
     1501 gcagcgacac aagcaattgc tataattaaa tattttatga aatcaaattt attaattatt
     1561 gaaattagga tgccaccagc tatcgtgatt gcagaaatca aaagtattcc tctgacatca
     1621 tatatgtttt ttccatccaa tagttctttg caaacttttc tataaaaaat ataatggatg
     1681 acgcagaaaa acatatatga gaatacagtt gtgtatgcta ccgcctgata cccatataac
     1741 tttataaaaa cataatttag tacaatattc ataattgcac acaaaaccga tggaataacg
     1801 acagtgagtt tcttttcaaa gtattcctgt actctagcaa acagctgaaa catatagttg
     1861 aaataaatac cgatacatat aggtacaatt aaattaacac tgtcgatata tttctgccca
     1921 ccaaatatca acacaatttc tttactaaat agcattaatg caaaaagcat agccgctacc
     1981 aaaccaagaa cttcattagc tctttttgat agtaaatcat attctcctga cttgattttt
     2041 tgatactgat aaggtgcaaa agtggaattg acagaatttg taacaaggtt aattagagca
     2101 ccaatagaat atgccacgct gtaaatagca acatctgacg aaccacataa gtaatttatc
     2161 ataattttat cagaaccatt cagaataaat tcagataaat agtgtggcat caacgataca
     2221 caaaatacta ctgcgaaatt ccacacttca ttatccttaa aatccttaca tcttctaaat
     2281 accgatatat acacagccac gccaacaaca ccagtcacta ggacattcat taaggctctc
     2341 gcctcagcgg taggagatat aaacagaacc gctaaacagc caactacaga tgagccaaca
     2401 gtaactgcaa gggtagctac taataaagtc ttataatcat atatatatcg tttgtgtaaa
     2461 gaccaacatt gtatttctgc ctgaaatata aaatatgaga acatacagac aactagaact
     2521 ggtgtcaatc ctaaaatttc tgccaatata tccttaataa aaatagcaat aacaaaccaa
     2581 aaaatagtca gtactaaagt caatccggat actgtcgaaa gaatatgttc ttgattatca
     2641 tattttacat aaagattcat catggctttg aacaaactaa gcgatgtaat catgagcaat
     2701 aaggattccc acgatagata agtgctgtat aaaccgtatt gttctgtaga caaaactcta
     2761 gtaaaaattg gggttgtaat cattgaaacc cctctctgta aaaaaccaca taccataaac
     2821 cataatgcag ccttaacagg aagtggagta ttcttatatc tgcttaatgt ttttacaatt
     2881 agattattac tggtcactgc tattttctcc taaacactat ttattcttga ttcaaaaaca
     2941 cattgagctc ttctggagta ccaagcacat gaaccttttt cgcatctact atgctaatag
     3001 tcacctttaa cccttttttt atcataaagt tatataatgg tgctatatat ttttcattct
     3061 tctccatatt agaggagtct gcataatact cttcatataa agctttatac agctttgccg
     3121 atgagaaata atacgcacca agagtacaat tatcagaaat gcgaactttt tcgcggactt
     3181 ctattacttc atttcgatcg ttaagctttg caaaactcca atgatcgcca tcagcatgaa
     3241 agcatggaat atgtccatct ccacaaatat cttcgtattt catctcattt gattccacgt
     3301 atgtatcaat attgtaaacc ataatctcat tgtcttgatt gcaataagga atagccaaca
     3361 tacatgtagt tgcttgacca tctgtcatat agtctatttc aatcacttct acgttttcaa
     3421 taccaaagta agcacaatgc tcctttataa aagctgaagc gttgtcttcc tgacgaacaa
     3481 caaaaatata cttatcaaca tttttattgt atccaaccaa actatccatg gcccaatcaa
     3541 ataaagttct tcctttggca ttaatcatat atttaggaac cgcataacca atttttcgaa
     3601 aacgacttcc caaacctgcc atcgtaatga taactgtcat ctttttttcc atagaactaa
     3661 cctccttatt tagaatcttt tttttgaact gttgcagatt tcatttaatt catctacaga
     3721 gcatctcaaa aactcatcag gtctaaccgt tcgatcatct acatagaagc ctttatgccc
     3781 cggccaaggc ttaccataca ggatttcatc atacggaatg tcccatttat ccaaccacgc
     3841 caagagcact tttgcagtat tagcatttat cattcccaaa tttcctttat aggaattaac
     3901 attgcgtgag gtgaacaatg taattttagc accattctcc ttatagaatc tcagtttttc
     3961 aaccatattc tcatacggca ccaaatcctc atatcgctca tccttcttct ttatcggaca
     4021 caaagtgcca tcgatatcaa acacaaaaga atattcacta tacatttttc tcttcccttc
     4081 tattgtatta attaatataa tcgtgcctta atgcctacat tgctaaaaca gtattgtaac
     4141 cgttattcat taaggcacaa tttatattag agtataactt tattacttac tcttgcaaga
     4201 agttccatac ctgtagcaag catcactatt tggtgatcaa aactttcacc gtgtaatgga
     4261 atcatactaa gaaatagcaa cgcttctatc aatacaatct tatcaaaatc gtccttaatc
     4321 tcgtccgaaa agaccgactt aaacaattca aataaatcgt aatctcttac acgcgtatta
     4381 attgtataat ctatcactgc acactcggta tcatattcta cagtaaatag atccttgatg
     4441 atataatcat atttaccatc taaactatga aatagttttg ctaattcata tctgctgtcc
     4501 ccataaatat catattttcc aaattttccc ctaggatcaa taaccttaac aaaggaacaa
     4561 ttggaatcta ccatcatatt agcaaaacac aaatctccat gtataataca aaattcattt
     4621 acatcataga gcatacttgg gataagattc tttagaagtt caattacacc ggttaaagaa
     4681 ataaacttac gaccattaat ttgaatttgt ttctcaaaaa aagctgaaaa tcttttatct
     4741 tcagacaatt tttgaaatct ctgcatggtt tttcgcaaat acatatcttc caatgactct
     4801 ctaatctttt catcttttaa ggtgtatcgc ttaaaatcgc tacagataaa ctttatacgg
     4861 ctaaacagat catgccactg gttatatttt aaatcaccat ataagtataa ctcatgaacc
     4921 gtatgatatg cataatattc catatcaaca tagggagcta cgtaagatgt agaataatca
     4981 aaaattctag gtcttacata ttcaatatca gcaggaagtt ttaaatacca ctttatttct
     5041 ccaataaatt tatccttgtc atcgctagtt ttcttcaata tccctcgatc tttatctata
     5101 gagatatgat taaactctcg tgctttaact tccaactttg tattgtaata tttatcgatg
     5161 tgtccaatat caaaccactt ttctgttctt acggccttta gcggacaacg ttcgctgtat
     5221 agctgtaaag cccgataaaa tgagtttatt cccccctgtt tccgactctc aactgcctct
     5281 cttaagcaac tcttcagaag ttttgacgaa gaaaacataa atacgccaat aaataatttt
     5341 tcacgtttat cggatacgta agcttcctct ttatcgtgga tatcagtaat tattccttca
     5401 ttaattttaa agtatgtcca agtactcgac acaaaatctt cagaataata gaatgtatcc
     5461 atttctatat cagacatact ctccataaca attgtatctg cgaagttaat tagaacaggc
     5521 tcatcttcat ctgataaccc aaaatacacg gtttgcccta gatcccctaa ttcaggaagg
     5581 tcacatatat gaattctgga atcatgatag tttttcagtc ttctatgaac cttatccgct
     5641 ttttcataac agataatatc caatgaatcg cagattgcat tatactgatt atacaaataa
     5701 tcaaagacaa tttttttatt aattggatag ataattgctg gtaacattcc tatactctgc
     5761 aattcttttt caacaacttt tgctgctgga attaatacct tcatctaatt actcctttta
     5821 caagtttcac taaaccaatt attgcatagt gcataaatga tttttaacaa attctaacaa
     5881 tgaacagaca ctatagtctt ggccataatt agcaggcaag gtgatgtctt ctgtaatcag
     5941 tactgtctta caaccagcat tttttccagc aattacatca ctttcactat ctccaaccat
     6001 aaatgattga cttaggttta tgttaaaatc ctttgatgct tctaataaca gtccaggttt
     6061 tggcttgcga caattgcaat caatttttaa ttctataacc tctcctgcat atcctttatg
     6121 gggatggtgc ggacagtaat aaataccgtt taaaaatcca ccagcatgcc ctagcattgt
     6181 ttcaagctta ttgtgaatac tattaagctc atcaacagta acttcacctc ttgcaattac
     6241 aggctgattt gttataacaa tacacagaaa acctagagaa ttaataattt taattgcctc
     6301 cgatactcca tcaattaact caaattcttc tgcatttctc aaaaaaccaa cgtatttatt
     6361 aatcgttcca tctctatcta aaaagattgc tttttgtgga ttggatagat ttttaccaac
     6421 aataattccc ttttgaaagt ccttaattac agctctatat cggtccggtg ttcccatatc
     6481 tttaacatac tctggagaat cgtagcaata catacgccct gtgttagcca atggtttcag
     6541 aatcattcta tctaaatcaa ttttgtatgg tagcccccca ccttcaacta ttgatttatt
     6601 tacaatttcc attaatggat tttctctcaa caccttcgga tttataacat gaagacctgc
     6661 atttactcgg tttttataat attcaggtct ttgatcttcc ttcgctaacc attgaagcac
     6721 tttcttattg tcatcggata taattaatcc actatcatac ggatgtgagt taggatgcgt
     6781 aaacaaagta acatctgcgt tattctcaac atgaaatcta atcatctgcc tgaaatcaac
     6841 atcaaatact gcatcagcat tcaaaagtaa aaacggttca tcacccagtt catccaacaa
     6901 aaaatacaat gcacctgcat tgccaagtgg agttttttca ataaaatatt tgattttaat
     6961 tcctaatttt gaaccatctc cgaaatgctc ctctattttt tcatgcaaat aggaaacagt
     7021 caaaataata tcattaaagc cttgatctct aagcgaacac aattctcgtt ctaaaactgg
     7081 aatgccatct ataggaatca ttggcttagg aatatccgga aacaattccg aaattcggct
     7141 tcctcgtccg cccgccataa ttactgtttt cataatatgc ccttccctaa agtacttttt
     7201 actataaaag ttaattactc ttcccaaaca aagtccatat atttttcata ttctgctttg
     7261 tattcgtatt ttccagtgta caaattcaac caatttataa aatcaaaatt atagcagtga
     7321 agtgcatctt ggctatcatc aatataatac gtaccataaa tagtattatt tgaataacga
     7381 cctacatatt tatgccagta caaatcaatt tgatttttgt taatagtaat aacatggttt
     7441 tttacaaact cccaatatgc cctaatagag cactcctcat tgccccccat tcgtgaaata
     7501 tagcttcgaa gaagctgaac ttctggagct aaattatttt cagatatctc ccttcttgag
     7561 actcctctag acacagctcc cttttctctc acatcactag gaatcgagaa gaggtttatc
     7621 atatcatcaa catcaccaaa atacaggaag tctgacaaac aatacgggaa aaacatgtct
     7681 ccatacggca ttgatagtaa cagtaatcgc tgattttgta ttaatttcca atcatcttcg
     7741 ttattaacag gatactgttc aagtaaactg cagaaaaacg ccattgcatt tggatggtat
     7801 attctttgat ctgttctagt tttacaaaca tactttgcac caagctgctt tgctctgact
     7861 attccaggca aagtgtttcc aacttgataa ttaatattta agtgtccagg cttttcaggt
     7921 ttctcactac aaataactat aactccaaga tcctctatcc ttttcaatgc cttaatatct
     7981 tcgtccttcc atgtcgaaag aataattaaa gcatttggat aacatttctt atagtaggcc
     8041 agagtattat aagagaaatc atcctttaaa catagtggcc cctgcattac aattgctaca
     8101 tctttgcaac aattaactaa acccatcact ggaacatcag acatgtcctt tgagcgcaat
     8161 tgaaacgctg cataaacttc agaattttct tctactgttg cacaatcagc agtcaatttc
     8221 caagatacga gtttacttat attatgacca aacatgttcc taaacacata tggtaaattt
     8281 tcgtacttct tcaatatgtt atataaaatc tctttcttat tcatgagatg cactcctatt
     8341 aatatttcct attctatgtt agccacactt ctacattctt gatagatgta ttctataacc
     8401 gctaagcata caggaatagc tggagtaaat atcggataaa accagtctat attaatccct
     8461 gttagcaaga catttaatgt aattccaaat gctaaatatt gatagccagt catacccact
     8521 tttgatgcaa gtaatgctgt tttgaaccct tttataataa acagaatatc aaatataagt
     8581 atacctacac catattgagt aattgtatag aaaaatccaa tatcagatag gtgtcctcta
     8641 actcctcctg gtaatataaa cgtaaattcc tcaccagtaa gaataccagt accgaacaaa
     8701 ggcgattgca aaaatttagg aataaaaaac caaactgaag caaatcgaga ttcagcagat
     8761 cctgcatatt cacctgtact gtttgtgaaa gtttcaacaa atgttgagaa catggtcgaa
     8821 ttaataaata tgactacaag caacccagct aaaacccaca ttgcaatttt tcttttcgaa
     8881 gaacctttct taaaaaggat atagcaacca agtacaataa tttgatagac aaggacagat
     8941 ctagaaccat gaataacagc agaatatgcc agtgcgctag caatcagtaa ataatatttt
     9001 acttttcttc tagctacaac ttgtcgctca atcatataca aagcaatcgg tattattata
     9061 attgtaaaac atggtggatt aattcttaaa aagcctccac gataccaatt ttccggggca
     9121 cactcacgat atatgttttc atagagaagt actcctgaaa atttctgaat aagtgaaata
     9181 gatgttctaa gaatgtatga aagaaatgtt acaccacata tcgtatttag cattgaatcc
     9241 aaattccacg cttggttaat taaagtacag aacaatggat acgccaataa tacatagtat
     9301 aaactcatac tttccctaga tttaacccat attgtcttat ctgagtagat gtaagctgct
     9361 attataacaa cacaaatcag taaagtgcag aaatttaaat atctattttt tctaaatgct
     9421 ggtaatgagg ctattaacaa acatactatt gctagaatga ctgtcacaag tctaacgttc
     9481 atcgtttctc ccaaccagcc gcccaaaggc ttcaatatgc ttgatgagat aatcattaga
     9541 aagaccatta gaaactgtat gattttccat ttactaatct gcatgttaat tattattcct
     9601 ttctaattgt tttactactc attcaaaatt tgtttgtatg cctcgtatgt gagttttgca
     9661 gatgccgccc aggtatactt gcggtttaca agctcatata tatcatcctc tattttgctt
     9721 ttctcagctg ggctaaggtt cacatacttt acaattgtgt ctgctaggct cttagaattc
     9781 aaattttcga aaagtaaccc tatctttcct tcctcggttt cttccataaa agcaggtaca
     9841 ttactaacaa tagttggtaa gcaataagtg tatgccataa gaagcgctcc acttccatag
     9901 atttctttat atggaaatat tgcggcatct gcatttctga acatactgtc catttcttca
     9961 tcagaaattc tctctggctt atatagaaca caatctgaaa cctttaaatc ttcaatcatt
    10021 tttttatagt cagtactatc ctgtttagga tgttgttgac ctgctatggt aaaatgaact
    10081 ttctttctta catccattgg aagttctgtg attgcattaa gcagtacatc aattccctta
    10141 tatggacgaa tttgtccaaa caagataaat tcaaacttat ctttatcata cgctctagat
    10201 atatgtttaa catctccata gatagcatgt ggacaaacat atgactttgc atttaattct
    10261 gggaattcag catataaatg ctgttctgtt actcgattgt gaacaatgaa accatcacaa
    10321 tttgaatata tattaaagtg ctcttggcga tccttttcac gaacctcatg tggtaacaca
    10381 ttatgaactg tcataattaa ttttttatag tgtctcttac ataaaacgta caatccgcct
    10441 tcatatttga gacttttcat caattgcaaa tgaacaatat cataatcacc aaatcttatt
    10501 tccttccaaa ttaagaacaa gcttttcaga aaaacaagtg ccgaaaacac tttatttgta
    10561 cttttatgat acaaaatatg tttgctctta attttaggat ctaaaggagg aacatcacgc
    10621 ttacacagca atgttaaatc aacatattga ttaagttctt tagaaagatc aaacgaatac
    10681 caattctctg gcatttggct ttcacacatc aataccttca taatactcac cttataacca
    10741 atcaacagaa aattctgctt tcagttttcc tttaatttta cgttttgcta taaacatttc
    10801 cagtatctct cgcattttcg tctgatattt tgtcgtttta ccataaagcg agtgattgtc
    10861 ccctgttcct aatacatata ctgctgcttt gaatggaaga ggttttaatg gacgcccttg
    10921 ctcttcacat gctggaacaa cgcccccatg tcgttttcta atgatccatg gattatcatc
    10981 acaatttgct gtcataactt ccggatatgc ctcaggcagg tcttccactg catattttac
    11041 tatacacgca cttcctgatg agaactttgg tagaaccttc atataatcgt ctccaacaaa
    11101 gtacacgtat cccgttttga cataaaatcc attttcctgg ggatgggaat tcacatattc
    11161 cgccaaatga gaacttacaa gatcatctgc gtcaaccatc atagcgaaac cgccgcccaa
    11221 ctctcgcaaa cgcattgcga gagcatgtgt tttataaccc ttatcaatca ttttttcgtc
    11281 ttgatttgtg ggaatagggg catccttttc gctaacttga ataaattcaa ctctgtcatc
    11341 atattcatgc gtgagtttag gaatttcatg gcaagcaaca atgattttga aatcaggatc
    11401 agtctgatta taacacgacc ataatgttcg gttaaataag gtactaacca tctcccaatt
    11461 gtttgctgcc ttcgcactca ttaaaggaat aacaaaatac aacatacaat ctctcctttt
    11521 agtaacgatt caaactacaa taatcattta catcaatatc ttttttcaat actctagccg
    11581 gaacgcctcc taccgaacaa ttaggttcaa catcattaat gaccacagca ttagccccta
    11641 ctattacatt gtcccctatt gtgatattac ctaaaatttt tgcgccagta gcgatatata
    11701 cattgtttcc aattgtaggc ataccaggct tattggatct accaccagtc agtacattcg
    11761 ttccgattat aacgtgatta cctatttttg tatcttttcc aattacacaa cctatgccac
    11821 cgtataagaa cttacaatta tctccaattt ctgtttgata tgaaattgag ctattatgaa
    11881 gtacataaat tagtgccttt acaatcttgg caaaaaactc cattttgtgt aagtaaaacc
    11941 atcgttctac tttgtataat ttatatgcat tcatgtttta tctccccatc tttttagcag
    12001 gtacccccca cacttcgtag ggtggaatag acctcaatac cactgtattt gcagcaacta
    12061 cagcaccttc cccaacgcat aattctgtgt tagatttaca aagaatttta gcacccacac
    12121 ataaaacagc gttctttttt actcgaatga tgatacgttc attactatct gctcaaccac
    12181 acgtcacatt ctgatagact ttaacaccat cttcaaggat tgtgtcagaa tgaatcacag
    12241 tgcctacaga attatgaaca aattcaacag agttccctat ctgtgcacct ttaccaatac
    12301 aacaaccaag aattttggct atttttctcg tgcaattatc aactatgttt aaagcatatc
    12361 gattcctcaa tgccattaat ttcgttactt ccatatcatt tatcaccttc caacatgcta
    12421 agcataattt ctcccgactt tgaccatcta aattctgtag ttacacgctg atatgctgca
    12481 tctatgatat cgttggtaaa tcgtccgtct tttaagaatg tcaaaatttc atcgtcagat
    12541 ttagccaaca ttccatatct attatccaaa ataatattct gtgggccagg tgcattaaca
    12601 gcaataatcc cgaggcgata gtacattgcc tctagcaaaa ccatacccca aatttcagta
    12661 tagtttagat ttacaaatac atccgataag caatataact cccaaatatc tttgttagga
    12721 atacgctcaa ttatttttac tctattctgc agtccaagta aatttatctg ctgcttcgtt
    12781 tgctcgagta aagcaccagt tcctaccatc agcaaataat tatgctcatc aagtttatta
    12841 aataaactaa tcatatctaa cggtctttta tccttttcaa accgtcctac atataaaata
    12901 acacgaacat tgcgaggaat attccatttt tctctgagag tagtaaaatc tattgcttcg
    12961 taattcttat gtaactgttc aaaatccaca caaacaggag caagtttcac tttatttact
    13021 cctaattgta ctaatttttc agaaactcga tcatttttgg caacacaccc atttttctta
    13081 taaattttat aatttcgatg cgccaatatt tcaataattg tctttatata tttattgcca
    13141 ctttgacttc gcgttatccc attataaggt atatatttta ttccattttt tacagtccat
    13201 gagtatacat gaggtactga tagttgaagg tccgcaaatt gtattagaac atccgcattc
    13261 ttatcaaaat tctttgttga taagaatcca tttgatccta cataacgaca cttgatatag
    13321 tgaatcatcg ccgtattgct taattgctct gttccaactt cctcatcact ttttacactt
    13381 ttatatacaa taacttcgtg gcctaattca gctaaccctc gagctaatcc tatttcctga
    13441 gaattatagg accccttctt accaaagtta ttcgtcattg taactactat aagtattttc
    13501 atctattttt attgcccccc tacttagatt caatagtata gtagatatac tttatacctc
    13561 ccaagatata ccgcctccat agtctacgag gttcctttac cagtctaaat aaccactcta
    13621 gactagcttt ttccatccat tcaggagctt tttccaaagt gcccgcaaaa aagttaaagc
    13681 cggcgcctac accgaacatt actgtgttat ggatcttctt ctggtgttcc cacatccaca
    13741 tttcttgctt aggcgcacca ataccaaccc acagaaaatc tggatttaag ttgttgattt
    13801 cctcgcaaat cttgctatcc tcttcttcat ttaacggacg aaatggtggg gaatacattc
    13861 caacaatttt gattcccggg taatctcttt ctaggtttgc acgaagctta tttaacactt
    13921 cgttatcttt tccaccatag aaataatgtg tttttccctg tctaacgcct tcttcaaaaa
    13981 ccattcccat aatatctggt gcagcacatc gttcacaggt aaatcctttg cgccgtccaa
    14041 ttttaacaat aggcatacca tctattgcag ccattgtagc ctggctatac atttcagcaa
    14101 ttttgggatt ttcctttgcc gaaataatgg ccggcactcc cacgagatca acagtcgcac
    14161 ttaccggaga tgttggcatg gaaaaaactt cccttacaaa ctcgttcttt gtagtagcac
    14221 aaacacctac tattccacac acagtgaaat cacgttttct tttatacata ttcttttcca
    14281 tctcagtaca tccttactca tatgttcttc ctccgcatcc tctaattaca cggaggaaga
    14341 acagcttata tacttattaa cccttaatct gcttttcaat ccaattgtag gattcacgaa
    14401 gaccctcttc caaagaaaca gtaggctccc aatccaaaat ctctttcgcc ttagaataat
    14461 ctgcgcaacg agccttatca ccttcaggct tagaagtatc aaagaaaggc ttgatgtctt
    14521 tgccagaaat ttcaatgatc ttatatgcaa tttccttgat ggaagtacag tgagaagggc
    14581 caatctgaat atgaccatga ccccaaccct tatccagggc gagcaccaat gcatttacga
    14641 tatcattgac atgaatgaaa gcacgtccct gctctccgct accccacaca ttaaaaggct
    14701 cttcaggatt attgattgct ttacgaatca gagcaggaat aacctgacta cgttcgccaa
    14761 aatcagtagg tgtgccataa acattatgga gcatcaggat acagcacgga attccggttt
    14821 ctttttccaa ataccccatc tccaactggc ccatcagttt gctccagcca taagcagact
    14881 caggaagagc agggaacaac tcctcttcac ggagaggctc aggattcaaa gtattctgtc
    14941 tggtcagagg gaaggagcat acggtaccaa catagataac acccttgatt ttctccttgc
    15001 cagccttacg gcaacaatca aaaacattag aattgatcag attattgatt cggaacaatt
    15061 cgccctggtt cttaaacaca tagtcaatgc cagccacaac atcagccaga tgaactacat
    15121 actcagtcgt accaataacc tttttagcct gctcataatc agtcagatca gcattgaaga
    15181 aatgagtatc caggtcgatg acaggatgcc catcttcgtc gttcaggtac tccaactttc
    15241 ctctccacag attatcagct acataaacat cccagcagcc ttccttcacc agtctcttaa
    15301 caagattgga gccaatcata ccgcaaccac cggtaaccat aattgtcttt ttcatttaac
    15361 attcctccaa attttattcg tttccaaaga atttatcttc cagcatcaaa caccaacaat
    15421 gatatatcgg caagtgatac tcttgaatca tgtatgtttc aacttcagga gccttaacac
    15481 aaacatctgc taccgtggca agttccccac cctttgcgcc cgtcaagcca ataactttta
    15541 taccgagagc cctagcaaca acagttgcgc tcataatatt cttgctattt ccggacgtcg
    15601 aaataccaag gaatacgtca ccagatctac caaagccaaa cagctgctgt gcgaagacac
    15661 ccaaaccatc gacatcatta atataagcag tagacaatgc ttcgtgtgcg accaaaggaa
    15721 ttgccgttaa accacactcg agatttttgg ctaattccgg acctcttaca gggtcaattg
    15781 caactaactt atcggcaaat tccttactta caggacgtgg cgtcttaaac cgcttcatca
    15841 actcgccagc aatatgttcc gagtcagcgg ctgatcctcc gtttcctgcc acaagaagtt
    15901 taccaccatt caaatagcat tcctccataa ttaggtatcc atcgataatg tcctgtttaa
    15961 tcgtctcaag tgtaggatat cgtttaatca ataagtcaat atgtttatta agtttttccg
    16021 ctaacattgt tactccttat ccattctgtt tttcaatata agtttccggc gtgtagtgaa
    16081 taactctagt tccaccattt tcaaattcaa acggaatata catcaaatca cgcatagccc
    16141 aacgaactgc atcctgtttc tcaggttgta catagaaaac caagaaacct ccaccacctg
    16201 caccgagcaa ctttccgcct aaagcacctg cagccatacc cttttcatat agttcatcaa
    16261 tgcttcctgt actaattgct ccaccagtac cttttttcaa tctccaagta acatcaagct
    16321 gtctaccgaa atcatctaaa tttctgttct tatcagtaag aattgcctca gcttcatcta
    16381 caagctcata catctttttc agtcttactc tcttatcctc tgtgccactg acgttgttag
    16441 ccttttgaac atcagaagaa aatctagtga atccggtaaa gaacatcatc agattgttgt
    16501 taagctgctt tttacgttca ggcgaaataa tgacaggcag cacctcataa ccatccacat
    16561 tgaaattaat tcgattgaac ccaccataag atgcggcaat ctgatcctgc catccaccgg
    16621 cttcattaca cagaactctt tcaagataaa tggcttcatc agcaagtttc ttcttgtcag
    16681 catacttacc ctccagtgca taaaaagcat tcaacatacc aactgcaaaa gaactggatg
    16741 tacccagacc agagcgagca ggtaaatcag cttcgtatgt aagccgaatt tcatgcatat
    16801 cgagcatttt catcgcatta cgaatcgcag gatgctcaat atcttcaatg ctagttactc
    16861 tctcagtacg agaataagat aactcagcgc tgtaatcaaa aaatctaggc agatgtctca
    16921 cattcacata acagtactta tcaaaagtag tagaaagaac tgcaccgcca ttctctttga
    16981 aataatcctc catatccgtt ccaccgccaa aaaaagacat acgaaacggt gtttttgtaa
    17041 taatcataaa tactctctcc taatcttagt ctctctggaa gatatcacgg gtatatactt
    17101 tttccttaat gtcatcaagg caagcatcgt agcgatttgc tataacagaa tcacacattg
    17161 ccttaaactg ttccaaatca ttcacaacct tactgccaaa gaaagtctct ccatctttca
    17221 aggtcggctc ataaatcaca acagttgcac ctttagcttt tacacgcttc ataacgccct
    17281 ggatagaact ctggcggaag ttatcagaat tggatttcat ggtcaaacgg taaacaccaa
    17341 tcacaacagg cttttctttg ccagcatcat actgatttgc ttctgcgtaa ttgtaataac
    17401 cagccatctg aagtacacga tccgcaataa agtccttacg agtacggtta gattcaacga
    17461 ttgcctcgat cagattttca ggaacatctg cgtagttggc cagaagctgc ttggtatcct
    17521 tcggcaggca atagccaccg taaccaaagg aagggttgtt gtaatgagta ccaatacgag
    17581 gatcaaggca aactccatta atgatctgct gagtgttcaa gcctttcatc tctgcataag
    17641 tgtccagctc attgaagtag ctgacacgaa gagccagata tgtattggca aacagcttaa
    17701 cagcttctgc ttcagtaaag cccatgaaca atgtgtccac attctctttg attgcgcctt
    17761 cctgtagcag tgtagcaaaa gtgtgtgcat cctcaaccaa acgctcatca tccatatcgg
    17821 tacccacaat aatacgcgaa ggatacagat tgtcatacag tgccttactt tcacgcagga
    17881 actcagggct gaaaataata ttcttgctac cagtctttac acgaacagaa gcggtgtatc
    17941 caacaggaat ggtggactta ataaccataa tggcatcagg atttacttcc atgaccagcc
    18001 taataacagc ctcaacagcg gatgtgtcaa aatgttgagt gcggctattg tagttagtag
    18061 gagccgcaat aacaacaaaa tccgcagact ggtatgctgc ctttgcatcc aatgttgcgg
    18121 tcagattcag ttctttctca gccaagtact tttcaatata atcatcctgg attggagatt
    18181 tacggttatt aatcagttca accttctctg gaatgatatc caccgctgta accttatggt
    18241 gctgtgccaa cagagtggca atactcaaac caacataacc ggtgccggcg actgcaatgt
    18301 tatactgttt cttcataata tttcctcttt ccaccactgc tgtggtcact actttcttaa
    18361 caaaatgctg tttgtgaaca gtaacctgct atttatataa aacagcccga aagctgtgtt
    18421 cattcatact taaaacagcc agctcctacg ccggcaaatt caatttttca taaatcccct
    18481 acccgtttag ggttatattg caagtttgag tcatttttat tgacctcgtt tggggttata
    18541 atacattttc gcattgaaat gtacctacat tttccactca accagtcacc aaaaagttta
    18601 taaattcact tattaccctc tattcttact ccaaaggtat gtttaacatc gctttattga
    18661 cctattttca ccccaaatgg aagtttgttt ggtacattat tggtctattc ccaccccaaa
    18721 ctgtctattt tgagcgagtt tttgtttttt atcattgcac attttcaagg ctcaaattct
    18781 aagcggattt actggcaggg agacattggt aaatacttga acaatttcac ggctttcatc
    18841 atcacatcct acgataataa ttctaattgg ataaagatta tcattaataa tctactttca
    18901 cgtaaaaatt ctgaactaaa taaaatctat tgataatatt tttttcttcc actttttgta
    18961 tatcctacag gtatagtgga tttaattatc cccaatgcct ctgaagtaac agacatcact
    19021 aattcaataa cacattcact accatagttt gtaggaacaa aaatgacaac aaaatctgct
    19081 tccttatgtg atgtttttcc atctgtccaa attttattac caatgaaatc tagtttaaaa
    19141 tccctcttag aaactagttc actctatatt tttattcagt ttcattagtt ctgttttttt
    19201 gtcttcagtc accatataca tatatatctt aattatctat ccatttcatc ctacgcattc
    19261 ttgcgtaaat acaattcact ctgttgagct gatataaatc attggtggta caaagataaa
    19321 atgataactg tttctatacc tccaaaaatt ccagtaaata tatctataga tagtttcaaa
    19381 aaaaattgtc ttagtttcat aatatttaag atagtggtac atactttata acaacgtact
    19441 tttccaaata ttattttccg ttatgaacat ccaatatatt acaaagttta aaagtttaga
    19501 tgaactataa tcttcatttc tgcacagtgg ataataaatt cttatagata aaaaatagcc
    19561 tcttctaaag tcacaaatac cttactccca cattttaagt aaacactctg cagcattctc
    19621 tttgttataa aatgatagat attcctcaat tttatctctt attatgttat tatcagttga
    19681 taccattcca ttaatgtttc agaataatta caatattttg ggaccggata actccctttt
    19741 gctcgtaacc actcatatcc gttaggattc actaaaagtt taccgtttat ttttcgattc
    19801 tttttttgaa ccgtcccatg aacataccga ttcaacaagc taaattataa aaattggtgt
    19861 gctgtcatta ttttttggaa aatttattaa tggctatcaa tatacttttg tatcatacta
    19921 aatagctcgt cagttcctat atcggatata ccaatattaa agcatttaga tcattatatt
    19981 taagagtggt atcatcccaa aatttcgaat attttctttt atataagaat aatgatactg
    20041 aattgcccca ttcacctttc tttttttaga ttttctacaa gtgattcaaa ccctccataa
    20101 ttacagttat tacttttgaa acgataatat gaacatgtgt aatctttttt attaacaatc
    20161 catcattcta tccctaacta atatgctcca ttgggcttga caataacata aaacgttttt
    20221 aaaatcaacc tcaagtcgta cattaaactt cgatgactaa tatactctaa atccaactca
    20281 accattttat ggaaactaac attatttcta tcactaactt gccacaaacc tgaacaacca
    20341 ggttttacat acaagcgttg aagatcatat ctcgtgtact cagctacttc cctctccaaa
    20401 ggtggccgtg gaccaattag actcatatcg ccttttaaaa cattccatag ctgtggcaat
    20461 tcatcaatgc ttttggcacg gataatttta cctattttag tgacacgggg atcttctttc
    20521 atcttgaaca ttgcaccttc tatttcattt tgatcaagta attcttccaa tttttcttca
    20581 gcatctaaac acatcgaacg gaatttatac attttgaatg tttttccatt tttaccaaca
    20641 cgtgtatggc aaaaaaatat cggacttcct ggctcttctt ttctgattcg ataagctaca
    20701 tagaacatca aaggagaagc taaaatcaaa ccaataatgc ttcctacaat atcaatcatt
    20761 cttttaaaaa ataaatagat atatcgtttt tcaacttttt ctttatccaa ccaaacttga
    20821 ttaggatgta cttcactaat acgagataat aaatcttcac tttccatact ttccctctct
    20881 cctcatttcc tttttatcta cgaataaaga actaaaataa accaaacttc ttctttttta
    20941 cctcttcata gactggataa ctgatttcat ccccgttgat cagatccttt gcgacttgtt
    21001 tcatctgtac tactttttcc ttaccaaagt ccttagcaat ctgctcatag cactctttta
    21061 agtaaaaggt acgcttagag accccatggg catcagaagc agccatctgc acaagattat
    21121 gtttgaccat cattttggct gttttctgga tgtcttttcc aaatacaccg acataacttg
    21181 gtgcggtgag ttgggccaag catcccatat ctaggaatgg cagcatatga ttcgggtctt
    21241 tacgaaaatg cgcgttgcgt tctggatgga cgatcactgg tgtctttcct agttgtaaca
    21301 actcaaaaaa gagctgttct gcatataacg gcacttccag tgtcggaaat tcgattagaa
    21361 gatatgtatc atctaaatct gtaaataaaa tttcatctcg gtcgatgtct tcgatcagtg
    21421 ttccggtaat acgtacttct tgtccttcca ataacgtcaa aggcaattgt cttttctcta
    21481 attctgcttg taacgaagcg actagagaaa tgacttgtga tttttcattg ctgtattttc
    21541 cattattatg atggggtgtg cataaaatat gtgtgatccc ttgttgaatc gctttttcag
    21601 ccatggcgat actggcatct atgttttctg ctccgtcatc gattcctggc aggatatggc
    21661 aatgtagatc gatcatttct cttgtctcct ctctttttat ttcttaattc ccgtagtaat
    21721 agccagcatc tttgctgtgt tctgccccat tgtatacaac accaaggact cgcgcttgta
    21781 ccatatccag caattctttt gctttagtca atgattcttt ccgtgacata ttttcacgta
    21841 cgaccaataa ggtgccatcc gttttggaag acatgatctg tgcatctgtt acggcaacta
    21901 ctggcggcat gtcgaagatc actacatcaa atagttgtct tgcttctgct aaaatctgat
    21961 ccattcttgg cgaacttagt agttctgatg gatttggtgg tttaggtcca cttggcagaa
    22021 tcgacaaatt ctcgactggt gttcgttgga tctcatctgc tacacttcct gatgaactaa
    22081 gaacggtact taatccgctt gcgttgttca acttgaacgt tttatagatg acgggcttac
    22141 gtaagtctgc atcgactagc agcacccgtt gaccagattt ggcaaaaaca acggcaatgt
    22201 ttgctgcagt ggtcgatttc ccttctccag gtcctgatga agtcacaaca atcgttttaa
    22261 tttgctgacc agctgcggag gcaaactgga tattcgtccg aatcgtacga tattgttcag
    22321 cgattggtga agagggggtt gtgagtgtga ccaaactgac tgcatgagtt tgggctgctt
    22381 tttgtttctg tgttcgtgcc atttttcttt cctcctagac tcttgagcgg cttctgcgtg
    22441 atggcgctgt tttatcgttt gtagcttttg gttgtgtcgg agctggtcct tttttacgga
    22501 taccagcatt caattctttc gctgacattt ctggtacagt ccctaagatc gggaagccca
    22561 atgtatccgt cacatatttt tcatctttta ctgtccggtc gagtaattca aataagaaag
    22621 ctagacctac gcctaccatc attcctaaca ctaagccaat cactagattc aatttattat
    22681 ttggcgaaac aggtgtcgta ttggcaactg cacctgagat gatcgagatt ttatcgacat
    22741 tcatcacgtc tttggcgttc tcttggaata cttgtgacgt tgtattagcg atttgttgag
    22801 ccgtcactgc atttgtgctt gttgcttgga tcgagaacat ttgtgaattt tgtgactgat
    22861 tgacggagat ggcatctttg atttgtccag cagtcatttt tacattgtct tctgtttcta
    22921 aacgatcttt gacttcattt agtactagat cactgacgat catatcctta tacgtattga
    22981 tcatttgcag gttcgtattg acatcattga catttgcagt atctgattgc ggcagtgtca
    23041 cgatcaattg ggcttgtgag ctgtattttg gcgtcaagat gaaaaacgtc acgatgcctg
    23101 agatggccaa gccagcaaac attgagatga ggattgttat cacgtgtttg cgtaatgttt
    23161 caaaaatttc tttcaagctg attgtctctt ccattttttc tccactttcc tatttattct
    23221 ctagattcat ttgatctttt aattcttttt tcacacgatc aagttcttga tcgctgactt
    23281 tttggtatga gatattgtct tgcatgaagc cttctccttg cagctgatct tgcttgatcg
    23341 taccaaatgc atcccgataa tctaaagcaa tctttttcat ttcatcaaag ctcatgtctg
    23401 ttttcatatt cgactctaga gcattcaaaa cggattgata gttgcttaca ccgttcagac
    23461 tcaacacttt tttcgctaca ccttctacga tctttctttg acgttcttgt ctgccgtagt
    23521 caccatttgg atcttcataa cgcatacgag aataagacaa tgcctgatcc ccgttcaatg
    23581 tgattttacc gatcgtaaaa tcatagccat cttgtgagaa ggtgaggtca ttattgactt
    23641 cgataccacc aactgcatca acgagttctt ttagaccttt catattgatt gaaacatagt
    23701 gatcgattgg gatgtctaca tatttttgta cggtatccat cgccatggca gctccgccga
    23761 atgcgtaagc gtggttgatc ttgtcttttg tgtcatgtcc aacgatgtcg acatacgtat
    23821 cacgaggaat gctgacaatc gttgtctgtt tgtcttcagg actgactgtg gcaaccatca
    23881 tcgtatctga tcttccttga tcgacccgac ctaaatctcc cgtatcaatc cccatcaata
    23941 gaacagagaa agattcttgt ttgtccagat caactggttt tgttcgttct ccttgggttc
    24001 gttccactga ttcgtaagtt ttttcaatag aatgtgagag atctagatat aattttgctc
    24061 ctactcctac gattgctaat actaatacga caagaattgc taaaataatt agaaatatct
    24121 ttttccctct tgatcttctt cttcgttttg ccatagtttc ctccgtttgc tagccttgct
    24181 tgaattctcg cttattaata gctcgtattg ctatagccca tttgctgagc gactgtttct
    24241 gcttttgacg cgtatgcggc tcttattttt tcattccgga tctgttcgat gagactgagt
    24301 gcggtcaaat attgatcgta agtagcagta gctgttactt gaccgtcttt cagcatcgta
    24361 tcgaatagct gatctagttg cgtgacttgt gcaatttggg tatcagcgaa tcctagatat
    24421 tgcataacga ccgttttcca agcactatcc ttaaaaaagc tcatattttc acgtacatgg
    24481 gcgacatctg cacttgccaa cttttctttg atgatgacat catccacagc ttgctgccag
    24541 tttgatacgt ttttagtaaa taatttattg acagccgttt ggatcttcag ttttgattct
    24601 gcatcctcta actgtgttaa gactgctttc ttttcttctt ggatcgcagc agcttcttta
    24661 ggtaattctg attccttgat gtcataatca tctgctgaaa gtttgataga agatagttta
    24721 tgtgacaaat ttgaaactgt ttcttctgtt atttcaggat ttaggaaaat tttttctttt
    24781 gtactgtaca gcttatctac ttcttttgat aaagaggtca cggtgtcttt ttgattggtg
    24841 atggcagatt ctgcgtaatt gatccgttga tgatgttgcc gctgattatt gagatggtat
    24901 ccaaacaagc aaatcacaat agcgcctgtg cctaccgcca cagtagccaa taacttgacg
    24961 aacggctttt ccatagattc actcctaaat attgatgata gataaataaa gatgtgattc
    25021 attcacatca gaatgagcgc tttttatttt aaaagcataa ttaaactaat atattcatag
    25081 aaatatttat aaacaggttt tccctatata atcataccac aaacagtttt cttgactagg
    25141 gaaattccta atttaaaagt aaataaaaca gtaacaagat tattattaat ctttttcatt
    25201 tttatttcct cacttttcat gagcgttttg aaaattctag caaagaataa aataacaaaa
    25261 attattaaaa tagaattaat aacagctttt atatttataa caaaaaaaca gagacacagc
    25321 acgtttcgtg catgctctct gtttttcaaa caaaagacta ttttgtgatg atttgatcca
    25381 agcttgctaa tgacaaagcc atggcagtta tttgactaag ttgtgttagt cggttcttac
    25441 gtactgctgg ttcatcagcc atgaccatcg tttgatcaaa ataattttcg atcagtggac
    25501 gaagagcgac aagctggtcg tagttttcgt ggatcgtttg gtcagcaaaa cttgctttca
    25561 ttgcttctac tgctttgtgt aattctttct ctgcgtcgtt ttcgaacagc tcagggtcta
    25621 cttctgattg tttttcaagc tgcgcttttt tcgctaagtt cacgacacgt gtcaatgctt
    25681 ccattgaagg tttgaagtct tcatctgcaa gatgttgttt gaacaattgt gctgctgcaa
    25741 atacttttgt cagatctttt tgttctgcat tcaaaacagc ttcgatgaca tcatgacgga
    25801 tattcttcgt tgtcaataat tggcgcagac ggcctttgat aaagtcgatc acctgttgtt
    25861 gtcccgctga caagccaatg ccaaaacgat ccgtatcttt actgataact tcactaatcg
    25921 tttcttgcag aacagacaaa ggaaaggccc attttttcga ttcgatgatt cgaacgacac
    25981 catatgcttg acggcgcaaa gcatatggat cgtttgagcc acttgggatc atcccaactg
    26041 caaagaaaga aaagatacta tctaatttat cagcaatcgc taaaacagaa cctactgtag
    26101 tctcaggtaa atctccttca ctggatatag gcatgtaatg ttcacggatc gctgttgcta
    26161 cggctggttt ctcgccttta agcagagcat atttttctcc catgatccct tgtagttcag
    26221 ggaattctcc taccatgttg gttactagat caaatttata gatttcagca gcgcgttgca
    26281 gatccatcaa ttcttcctca gatagtccta cttgttcgcc tatgatgcga gcgatgactt
    26341 gtacccgttg cattttctca tagatgctac cgattttttc atggaaagta acagttttta
    26401 atttttcaac gtattggtcg attgaagctt tcttgtcttc attataaaag aattccgcat
    26461 cttctaaacg agcagtcaat actttttgat tgcctcgtac cacattttcc aattttaccc
    26521 gatcgccatt acgagcagaa ataaaatgag gaagcaacat accttgatcg ttccgtactt
    26581 cgaaataacg ttgatgttct ttcatagaag tgactagtac ttcttcagga acagatagat
    26641 atttttcttc gaagtcgcca gaaaagacag ttggatattc gactagattg ttgacttctt
    26701 ctagtaaatc ttcatctaga tcaatgatcc agtgattttt ttctgctaat tcgtttgctt
    26761 gtgtgatgat catttctttt cttttttgcg gtgaagcaat aacaaattgt tcattcaatt
    26821 tttcttcgta ttcttttgca tgcgtaaatg tcacatcttc gcctaagaaa cgatgacctc
    26881 ttgaaactct gtctgttttg acatccaaga tctcaaacgg gattatttcg tcatctaaca
    26941 atgccacgat ccagtgaata gggcgaatat attcaaaatc gtattctgcc cagtgcatcg
    27001 ttactgggaa agtgaggctt ttaatgacat ctgctaaacc tgtcaatact tcttttgctt
    27061 ctttgccgtg agtgtatttc gttacataga catattccac gccttttaat tctctaaaag
    27121 tgatagcatc tgtcgtcaga ccttgtccgc ggacaaatcc ttcagctgct ttcgtccagt
    27181 ttccatctgc gtccaaagca atttttttgg ctggtccttt gacttcttct tcgctgtctg
    27241 cttgacgttc tggaatgttt gttactttga ttgctaagcg gcgcggtgta gaaaacgttt
    27301 cgatcgtatc ataagtcaat tggttttcat ctaaaaattt tgctgttttt tcttctaatt
    27361 gtttcatgct tggtgtgact acatgagcag gcatttcttc cagcccgatt tcaagtaata
    27421 agtcttttgc catcttattc agcctccttc acgttttctg gatttgctgt gtttttattc
    27481 aataaaggga atcctaattt ttcgcgttct gccacaaaga ttttggctac agcacgagcc
    27541 atgttgcgga tacgggaaag ataacctgca cgctctgtta cggatactgc accgcgagca
    27601 tctaataaat tgaatgtatg gctacatttc aaaatataat catacgctgg atgaacaaga
    27661 ttttcatcga tacagcgttt agcttctttt tcaaaacgat caaaattgct tagtagcagg
    27721 tcttggtcgc ttacttcaaa agaatattta gaatgttcat attctggttg tttgaagatc
    27781 tcaccatatt tcacgccatc agcccattcc agatcataaa cactttcaac ttcttggata
    27841 taagaagcaa gacgttctag tccataagtg atctcagaag taactggttt acaaggtagt
    27901 cctccgactt gctggaagta cgtgaattgt gtgatctcca tcccatcaag ccatacttcc
    27961 cagcccacac cggcacaacc catcgatggg ttctcccagt tgtcttcaac aaagcgaata
    28021 tcgtgttcta atggatcaat tcctaaaaga cgcaagcttt ctaaataaag ctcttggata
    28081 ttttcaggtg aaggtttcat tacgacttga aattgatgat gctgatacaa acggtttggg
    28141 ttttctccat aacgcccgtc agctggtcgg cgggatggct ctacataagc agcattccat
    28201 ggttccggtc cgattgcccg taagaatgta tatgggctca tcgtacctgc tcctttttct
    28261 gtatcataag cttgcatcag catgcagccg tttgatgacc aaaatttttg taatgttaaa
    28321 atcatatctt ggacggtcaa ttttttactc atctgttttg cccctttcaa tttttaagcg
    28381 ttgctgtcaa taagaataca ggaaagaaaa cgacaaaaag tccctatgtc tgattacaga
    28441 catagggacg aataatttcg cggttccacc ctacttccga ataaagattc ggcagcttca
    28501 tttatcgtac tcgcaagtgc ctcttcaaaa atcgtttggg tccggcttcc actctcccga
    28561 actcgctaaa ccacgtgttt tttactgatc ttggtcaatg tacgtattca ttttgcagtt
    28621 ttctggtttg tataatagat cctctcagtg aacgatctat ttaatctacg gttaataata
    28681 gacggaagtc cctgtatttg tcaaatagtt ttgatttttt tgttgtatct ttcatttatt
    28741 cttctttttc aggtatctct ttttcaggca tatttttctc tggcgtcttt aatacgtgtg
    28801 cccaagactt catttgatca atgaactttt tgctttttag atgaataccg acatattcat
    28861 catacaactg gtcaatgagg tcacggattg cctgcttcgt ttcttctttc aagtggattc
    28921 cactgatctt atcataagaa atagccgaaa acattcgaac gaaataaaca gcgcgaggat
    28981 ctgcatgata acggtgttcg tccattggcc agtgtttctc gcatatcaca ccgccatatt
    29041 tggaagaata gtcaaatttt ccttttgttt ccccgcatac gacacagtgc gtccaaattg
    29101 gcgcgattcc gaagcgttgc agtatttgca cttcaaagat attcgtgatg atttctgcat
    29161 catctccttg gtccatccgc tgcagagctt gttgcgtaaa ttggaataaa tgcgggtcat
    29221 attgatgatc ttcgattgct gcatctacta gatttagcaa atacgtacca taaccgctca
    29281 aaaagatatc ttcttggatg ttccgaaacg catggacgtc tttgacactg cttaaaaacg
    29341 acaaaccttc acttcgaaaa ttaccgatat agactgcttc ggtaaagggg agcaaagccg
    29401 gagctaatgg ctgattttgc cgatggattc ctttgatata aaacatcatt ttgccagaag
    29461 attccgtaaa gattttgact aatttatctt tttctttgta attacggcta gataaaatca
    29521 agcctttcga ttctacaagc tggctcatat tctccctcct aaaaaataaa tctggaaaag
    29581 cagattctgc cgatccagat tatttatgtt tcgatcttcc gctgtttttc tcaacgtacg
    29641 gatttttatc cagtttattt ctatacctaa cctataagaa gtccagaata tcagtactcg
    29701 tcttttcggt agccgaagtc ttgcagatag acttttttgt ctcgccagtc tttttggact
    29761 ttgacccaaa gttctagaaa tactttgtct cctaaaagat tttcgatatc ctttcttgct
    29821 ttcgttccta cttgcttcag catttttccg cctttgccga taatgattcc tttttggcta
    29881 tctctttcga cgatgatcgt ggcctggata tggattttat cattctcgtt tcgcttcatc
    29941 gaatcaacaa cgactgcgac agaatgaggc acttcgtctc gtgttaaaaa caagactttc
    30001 tcacggatca attcagaaac gatgaagtat tcaggatgat cagtcacttg atcatctgga
    30061 aaatattgtg ggccctctgg catttcactg actaatacat ccattaagcg ttcgacattg
    30121 tttccttctg tagcagagat cggaatcact tgtgcaaaag gcatctgcgt cgaataatct
    30181 tcgatgattc ccagcaactc gtctggatgg atcttatcga ttttattgat aatcagataa
    30241 acaggagaat gcacgttttt tagacgttca ataataaaat cgtctccccg gccacgtttt
    30301 tgatcagcac tgatcataaa taagactgca tccacttctt tcaacgcact gtaagctgct
    30361 tctaccataa aatctcctag acgatgcttt ggtttatgga ttcctggtgt atcgataaaa
    30421 atcagctgag cttctggtgt agtatatact ccttggattt tatttctagt tgtctgtgcc
    30481 ttgtcactca taatggcaat tttttgaccc acgattcggt tcaataatgt ggattttcct
    30541 acattcgggc ggccgacgat tgcgacaaac cctgatttat gttctggcat atacgttctc
    30601 ctttttaatt aaacaacaaa tgatatattt tagggacaaa taaaatcaac ccaatgatga
    30661 cagcaaaaca agcggtcact aaaactgctc cagctgccat atctttgatt tttttcccaa
    30721 tcggatgaaa atgaaaatcc gtaaacatgt ccactacatt ttcaaaaaca gtattgatga
    30781 tctctactat ccaaacgaga aaaacagcta aaagcagcca taaccactct atccgatcaa
    30841 gctggaaaat cacgcccata aataaagcaa ggataccgaa cgcaacatgt ttcctcatat
    30901 tgcgttcttc ctcaaaaacg gttttgactc cttggacagc aaattccaca gacatcagga
    30961 aatgtttgtt tttctctacg tttttatctt ttgagtccat aggcatccaa gatctctttc
    31021 tgtaaaccaa acatttcttt ctcatcttct ggtgtcatat ggtcataccc gttgatatgc
    31081 aaaaatccat gtaccgctaa aaagccaagt tcccgatcat atgaatggcc gtaagcttct
    31141 gcttgttcag cagcacgttc aatagagatc atgatgtctc ctagtacacg aggtaatgga
    31201 ttctctccat cttcaaaaat cactgggatt tcgtcttcgc cttcttcttc cagagcaaaa
    31261 ctgatgacgt ctgtcggtgc atcttttcca cggtaatcac gattgattac ttgaattgcc
    31321 gcattgtcca tgaaagtaac agacatttct gtttcctctg gcagctttaa ataagatgct
    31381 gcaaattgca gcaagtcatc gatttctttc attttctctt ctgagacttg gtttgtttca
    31441 tccataaagg taatatccat tatacatcgc ttctttctat tcttcttgta cttcctttat
    31501 cttctcaact tctgttttca ttttaggata tttgatccga gaatggaagg tgctacttaa
    31561 accgctgatt aatgattttt ccacttttcg gatttctttc aaggtcagtc cactatcgtc
    31621 taattgacca tcggaaatac gctcttcgat aagattatgg acaaaacttt cgattttttc
    31681 gctcgtcgga tgatccattg cccgtactgc agcctcacaa ctgtcagcaa tattgacgat
    31741 ccctgcttca cgactttgcg gttttggtcc aggataacgg aattgctctt ctgttacttc
    31801 cggattgcgt tctttcgctt tgatgtagaa ataacgcatt agcgtggttc catgatgctg
    31861 tttgcaaata tcgatcacca tttgcggcat attataatct tccaatattt tggctccatc
    31921 tgtcacatgt ccaaagataa tatgtttact gtcttctggc aataagaaat tgtgcgggtt
    31981 ttccgctcct gaaggcaagt tttcaacgaa aaagctagca tgtttgatct tgccgatatc
    32041 atgataatag caagctactc gagttagcaa agaacgtccg ccgatttctg ctacagcgtt
    32101 agcacttaga ttagctacca tcatactatg atgataagta cctggcgctt cttccagcaa
    32161 ctgtttcaat aaaggatgat ttggattgct gagttcattt aatacaatta cactgtcatc
    32221 attgaccatc aattcaatat atgggtgtag accgatcgtc agcaagaatg agaagagtgc
    32281 accagtgaac ccgcagacga gcattaacca agtcgttgca tcaccaaagc tcattccttg
    32341 atagacgatc aaaatgacat ccatcatcac aggaaaaata atgacccaca tggcagcaga
    32401 taatccttgt tctgagatcc gtttgcgtct gacaatcgtt gccatgagcc cagagaaaac
    32461 ataagacatc aagataatcg ttagaaagtt cgtgccaatc gaatcataaa aaatgaaaag
    32521 tgcggatact gcttggaaaa taccagccat gatccctgct cttcgattca agaaaaagct
    32581 taaaacaagt ggtgcaaaag cagcgggata aaacagcggg atataagtag cttgttccgt
    32641 ttggaataat tggaaaaatt tcatcagcac tatgctgact gacatagctg tcacatagaa
    32701 aagcacgtat tttgttcttt ctcctgcatt ttggaattga agtgaattat aaatcagtac
    32761 gccgatttga agcaaaacag ctaaaaccat ggcaattagc ggaaaaatcg aagttgtttg
    32821 attagtcagt cctagtaatt ccaatttttt catagctgaa gcatcgattt gattaccttc
    32881 acgaacaatg atttctcctt ggaagatcat cactggttgt acagcttctc gtgcggattg
    32941 tttcaattct tctgtctttt tctcattcaa tacgtcattc actacgatac cttgatccac
    33001 taagtagcga atcatttgtt gttgtgctgg tgtgacattc aaatattgga tttgctcttc
    33061 tgcttcttgt ttaaaagctt ccaattcact ttcacgaact tgtttgctca tctgttcgtc
    33121 aatgagcttc agactctcat ccctcacagt atgaatctca gtttcagtca tttcaaatat
    33181 cgtcgaataa aaattgttcg gtagtttttg ataaaacaca acattttctg cattcacatt
    33241 ttcaaaattt ttcttcagcg cggcgatccg ctcttctgta gtaggctttg ggatattttc
    33301 atcttccttt gccttatcaa tcttttcgtc ataagatttg ttgatggcat cattcgtctt
    33361 atcgatcaat tcaaatagtt gcttgatccg attgttctgg tcatctgcaa gatctttttg
    33421 gtaagtgtat tctggagtga ctgcttctgc tgccagtttt cttttttgtt cggtttcttc
    33481 cgtgttctcg atcgttttgt tcgcacggat actttcttct gctacttggc cttctctgaa
    33541 atcattggcc ttttgtttga cactactaaa tgtaacgccg cagataatga taaaaaacaa
    33601 gaacagcagg aaaggcaatg ctgcctttcc aagtttttct tgtagtttct gcagtgtttt
    33661 attcaacatg tgcttatcct cctaagcaaa gcttattctt gatggagatc tgccttttca
    33721 taagctttga tgatttcggc aactacaggg tgccgaacaa cgtcacttgc ttcaaaatta
    33781 acaaaatcga ttttcttgat ttgctttaat gttcgttctg catgaacaag accacttgtc
    33841 gtccctcgag gcaagtctat ctgacttgta tccccattga caatcatttt tgattgataa
    33901 ccgagacggg tcaagaacat tttcatctga gcgactgtcg tgttttgtgc ttcgtccaag
    33961 ataacgaatg catcatccaa tgttcgcccc cgcatgtaag ctaaaggtgc gatttcgatt
    34021 acgcctcgtt ccatcaatcg gttcgtatga tccaatccaa aaatttggta taaagcatca
    34081 taaacaggcc gcagataagg atccactttt tcttttagat ccccgggaag aaagcctaga
    34141 ttttcacctg cttccacagc aggccgcgtc aaaatgattt tttgcacttc accttttttc
    34201 aaggcagcga ttgctaatac tactgcaaga aaagtttttc ctgtcccggc tggtcctacg
    34261 ccaaatacga tatcatgttt ggctaccgat tcgacatatt tcttttggcc gctgtttttt
    34321 acccgtatag gttttccatt acggtctttg acgatctctt cctcatacat ctcaacaaaa
    34381 taatctaatg tacctttttg ccccattttc aatgccgtca caacatcggg cgtacttacg
    34441 tggattcctc gtttgatcaa ttcctgtaat gtccgaatga ctgaggcagc caaggaaatc
    34501 tgggattgct caccaatgat ctgaatgatt tctccacgtg tatggatggt tgtttccgtt
    34561 gtttcctcaa tcagttttat atgcttgtcg tgtgcaccta aaagcatgct gacatcatca
    34621 gcagccgtca atctaatctc taaagaacta gactcttccg tcaaaaatag acatcccctt
    34681 tttttcgatt aattctttcc tattttacca tactcagaag aaactatata gcaaataaga
    34741 aaaggttcta aaagagttgc ttaaccataa gtaccaagaa acgttaaaaa actagccgct
    34801 tccattctct aaaggtctcg tttgaataaa aaaagctgat catgtaagct atgcataaga
    34861 tagaggacaa gtattccgtc taacttagca agtattctct gggtattttt cttgtttcaa
    34921 aaaaagaaaa caaaatattt gaaatattct tgcatttcaa aaaaaacagg tgtattataa
    34981 cgtcaacaaa taaatataca gcaaagcgtc gaggaaaaca gtaggctatt cagtgattta
    35041 ttcccagtga gtcatgtaag tgagaaatga caataaatcg aatagacgaa catcatttcc
    35101 gagtcaatgt cgaaaacgta gatcattgtg gctgcctcca ttatcaggct agcggataac
    35161 tttatcgaaa agcgtccgtg aatgaagaag cttttttaag cgaaaaaagg tggtaccgtt
    35221 ctagaatcta gagccctttt cccaagtgga aaagggcttt ttttatattt taaggtggtg
    35281 gttttcatgg aatctgatat tagtggtatt tctagtttct gcaacgttta ttttgttact
    35341 caaaatgata attattggag gaaaaattta tggaagaaac aaaaacttat tcatggaagc
    35401 aattattgat ggtcagttca cttatcttcg ggatgttctt cgggtcaggt aatctgatct
    35461 ttcctgtaca cttaggtcaa atggctggat caaactggat cagcgctggt gtaggatttg
    35521 ccatctcagg cgctcttttc ccattattag ctatcttagc tgtagtagtg acaaaaagtg
    35581 atggtctgta tgacttagct aaacctgtcg gaaaatggta tgctgccttg ttcttgatcc
    35641 ttgttcattt aacgatcgga ccattctttg gtacaccgcg gacagcagca actgcttttg
    35701 aaatggctgc taaacccttt ttgcctgaaa aatatgattc attaggtatg tttttattct
    35761 ctgctctttt ctttttactt gcttatttcc ttactgtaca tccaacacgt ttggtcaaat
    35821 atgtcggaaa gtatttaaac tccttgtttc ttgcattatt agctatcatt tttgtcgttt
    35881 ctttattcca acccatgggg aatctaaacc aatctgctgc agattcttat cagacgaacg
    35941 ctttgacaaa tggcgtttta gaaggataca acacggttga tgcagtagct ttacttgctt
    36001 taagtgtcac ttttgtccat gcagttcgtg atcttggttt taaagataaa aaagtcacag
    36061 aattaacagc aaaagctggt agcctgagcg ttgcgttaga agtcatgatt tattttggtc
    36121 tggtccttct cggtgcgatg agtttgaata agatgtcttt atcagaaaat ggcggaactg
    36181 cactttctca gatcactaat ttttatttag gtaacttcgg tgctagcttc ttaggggtaa
    36241 tggtcacatt aggtgtcttc actactgcta tgggactcgt tgtttctttt gcacaagatt
    36301 tccataaact gttccctaaa gtcagttata tgacatggct gcggttaacg acttttgtct
    36361 cttttgtcgt tgcgaatgcc ggattggata atatcatcca atggtcttta ccagtattga
    36421 tgcttttgta tccattgtca cttgcgttaa tcttactttc cttaacagca aaattcttcc
    36481 aaaagagtcc atttgtctat caagtaacga tgttcttttc tgccgttcca gccgtattgg
    36541 atatgttggc aaattcgcct gcattagtga gtcagcaaac tgtcgtagca agcttactag
    36601 gattttatca tcattatgtt ccttttgctg cattaggtct tggctgggtc gtcccaacat
    36661 tgcttggtta cgctggcagc ttgctctttt attatgtata tcgcgtatca ggatataaac
    36721 aagaagcaag tgagttacca gaagaataac caaatcaaac acaatttaac ataagagata
    36781 ttaaacagga aaaaaacagc tagaagaaag aataagattc tttcttctag ctgtttttta
    36841 gttctttttt tacgaacaca aaaaactgcg gataatcact gtccgcagtt taaatgataa
    36901 aattaagatt gtaatagttc tttcacaatc gcattcactt ggtttccatc tgcttttcct
    36961 ttgactttag gcataattgc acccataact ttgccaaatt ctttcattga tgaagcacca
    37021 gtttgagtga ttgcttcttg aacaagttgt cgaatttctt cgtcggaaag ttgttccggc
    37081 atatattttt cgactattac aatttcactt tttacttttt cagctaaatc gtcacgtcct
    37141 gcttcttcaa actcatgcaa agaatcacgt cgctgtttca tttcacgaga caacaccgtt
    37201 agttcttctt cttctgtcaa gtcgtgacct tctttaatct gctcgttttg tatagatgac
    37261 ttgatcattc ggatgacttg taaagattcc ttatctttcg ctttcatcgc tgctttcatg
    37321 tcatcgttta atctacttag tagtgacaca ctaccaactc caattcatca cagaactaga
    37381 attttttgcg ttttctagct gcttcagatt ttttcttgcg tcttacactt ggtttttcgt
    37441 agaattcacg tttacgagat tcttgtaaag tacccgcttt tgacacggaa cgtttgaagc
    37501 gacgaagagc atcgtcaagt gattcgtttt tgcgaacgac tgtttttgac atgttaattc
    37561 cctccctccg agcttaaaaa gtaaccgtaa ttgttattga aatatatctc aaaaaacaag
    37621 actgtcctgt aaatattata tctaatgctg ttttgaccgt caaggaaatc ttgctttttt
    37681 ttaaaattat caaatgttat tttatttaaa tccttattga caattttcac atcttccgaa
    37741 aatctcgaat ctatgccctt cgatcgtgca tccacctagc tgttcttcga aataattcat
    37801 cggacacata tggatttctt tcgttgttcc gcacactgta cagataaaat gatggtgatg
    37861 gccgattttc ccctgacagc aatgaaaacg aaacttcatt tctccattta aatcggtttc
    37921 ttccagtaaa tcgatctctg caaaatcatg gagattccgg taaatcgtat cataacttac
    37981 ccctttgaat tcctgattca tatagtcaaa aacttcttta gcagatacgt agcggttacg
    38041 cttcactaaa taagttaaca atgcttctct ttttttagta tatttaaaac cgttattttt
    38101 caatgtttct aatgattgtt cgatcaatgt ctgttttttc atgacttatc cctccaaatc
    38161 aaaatgatta cgaagtacgc attctagagt atggtataat aaacataaaa aaaatgcaag
    38221 tgaggtttta tccatgactt ccgattctac agaaatcgtt actttttttg tcatctccga
    38281 ctctgctgga gaaactgcga caaaactagc gcaagctact atggctcagt atcctaccgt
    38341 tgagttcaac ctattccgca gaacgttcgt gacagatgaa aaaacattaa ggcaggcatt
    38401 gcaagatgca ttagaagaaa aagcacttgt cctgcataca ttaatcaatc aagaactgat
    38461 cgagataaca cgttcttttt gtgaagaaca tcaattattt agttttgatg tgatgacgcc
    38521 accgatatca gaaattgaac gtttaactgg tatcaagcca attcggcaac ctggtgccct
    38581 ccatttattg aatgagaact atttcaaacg gatcaaagca atggaatttg ctgtaaaata
    38641 cgatgatggg aaagatcctc gtggtttttt agaagcagat gtcgttttgc taggcgtatc
    38701 ccgaacttcc aaaacgcctt tgagcttgtt tttagctaac aaaaatttaa aagttgccaa
    38761 tttacctttg atcccacaag cacatattcc caaacagctt tgggagatcg atcctaaaaa
    38821 aatcgtggga ctaacaaata acccagatat tttaaataat atccgtaaag aacggatgcg
    38881 ctcttacgga ttaaaccctg atactgctta ttccgatatc gaaaaaatta gagctgaact
    38941 cgattttgcg aatgatcttt atgaaaaact aggatgtgta gtgatcaatg tagcatcttt
    39001 atctattgaa gaaacggctt cgcttatttt gaatgcttta gacctagaag atcatagtta
    39061 ttatggaact gaaacaacag aaaaaagcga ttgatcattt ttgtcttttt cttaaaaaac
    39121 actggagtgt gacaacgaaa tttcttcgtt gtcacactcc agtgtttatc tatttgcacc
    39181 tatcgttatt gatgttccac atgtttgagt gtctggttca aaatatccag tacatgagaa
    39241 tcatcaagac tatacaaaat cgcttttccc tcgcgatgag acttgacgac atgattttct
    39301 cttaataaac gtagttgatg cgatacagca gactgctcca tttccactgc ttgggtgatt
    39361 gctgtcacat tttgttcccc gtctttcaga tatagcagaa ttttaagacg agtgggatca
    39421 ctcaacattt tgaataattg actgactttc tctacttttg atttttgcgt gtctggcaat
    39481 ccattcacct ccaacttgaa aaaagactga cttctaaagt ttaccacttt ttccatcagt
    39541 ctcaagtttt ttattcttct gtcatctttt tgataatcgc ttcataagag gctacttttt
    39601 cggctgcgtc ttctgtagaa cttcctttta caccaatata aaacttgatt ttcggctcag
    39661 ttcctgaagg gcggatagca atccagccat tttcttccaa tgtatatttc aatacgtcgg
    39721 atggcggtgt tgtgagtttt tctacgtttc cttcacggtc tgttctcgtc aattctttaa
    39781 agtcttctgt ttgaataact tttgctccgg caaattctgt cggtgcttct ttacggaatt
    39841 tttccatcaa agcagagatt ttcgcagaac cttcttgtcc gctcattgtc acagaaatcg
    39901 ttttttctgc gaaatagcca taggtttcaa aaatcgtttg caagccgtca tacaacgttt
    39961 tgccttgttt tttatagtaa gctgctactt ctgctaataa aagcaatgct tggatcgcgt
    40021 ctttatcgcg aacaaaaggt ttaactaaat aaccataact ttcttcgaat ccaaacataa
    40081 aagtatgtga atggttttct tcgaattgtt ggattttttc agcaatgaat ttaaaccctg
    40141 tcaacacatt gaacatggta gcaccgtagt gttccgcaat tgctgtaggc aattcgctgg
    40201 aaacgattga tttcaatacc gctgcgtttt ctggtaaagt gcctcttgat tgatgtgctt
    40261 ccaaaatata ttgagcaaac aatgctccga tttggttccc agtcaatact tcataagaac
    40321 catctggcaa acgaaccgct gcgcctaaac ggtctgcatc aggatctgtt gcaatcagca
    40381 agtcagctcc ttctttttct ccaagtcgta tagcatattc aaaagctgaa tgttcttctg
    40441 gatttggcga tttgaccgta gtgaaatctg gatctgccac agcttgttcg ggaactagta
    40501 cgaattgttc gaatccagct tgtttcaacg cacgttcgcc caacattttc cctgttccat
    40561 gaagtggcgt gtacacaagt ttcaaatctt tccccattgt ttcaaccaat tcacgatcaa
    40621 tcgtcactgc tttgatttct tctagataag cagcgtccac ttcttctccg atgatcgtga
    40681 tcaacccgct atgtttagct tcttcgtcag ataatacttc gacttttagc ggattgctga
    40741 cttcacggac atatttcgtc aatgcatctg cgtctgcagg aggcatttgt ccgccatctt
    40801 ctccgtagac tttatatcca ttgtaagccg ctgggttgtg agatgcggtt accatgattc
    40861 ccgcaaacgt cttcaaatga cgaactgcaa aagaaagctc tggtgttgga cgcagacttt
    40921 cgaatacata agacgggata ttgtgatgtg ccagtgtttt ggctgcttcc attgcaaatt
    40981 ctggtgactg atggcgtgag tcataagcga tagcgacacc tcggcgtttt gtttcttcac
    41041 cttgtgtatc catgaaacgt gctagtcctt ctgttgcttg tcttaccgta tagatgttca
    41101 ttcgattgat cccaggtcct aagattcccc gcatgcctgc agtaccgaat tccaacggtg
    41161 cataaaaagc atcttcaagt ttttcaggat cttcacccag atcatttaat tgttttttta
    41221 agttttcttc taaattttct tcatgtaccc attgttcata cacttgttcc caagacatga
    41281 aaataacacc tctttctgaa atatggttct taataagtat agcattcact tattagatat
    41341 gaaagtatga ggaccaaaaa acgcttaaat caagaaagga ttcttttatc aagcatgatt
    41401 gcaagtattc acataaatcg gattcagtgg atttcacgcg aaaaaaaaga gtaaaagaac
    41461 aattgaaacc gttctttcac tctttttaaa cttatgctgt tgtttcttct aaagactcca
    41521 agtatttata cacttgttgt ccagcaatac cgccgtcacc aacagctgta gtgatttgtc
    41581 gcaaatcttt ttcacgaaca tctccgatgg caaaaacgcc tggcatattc gttttcattt
    41641 cgttgtctgt tggaatccag ccagcttcgt tcgtcaaacc tgcttctcta aaaggtgcag
    41701 ttaatggatc cagtccaaca tagatgaata ctccgtctgc tgctaaatca aattcattgc
    41761 cggttttgac attacgtgct ttcacacctg tcactaccat ttcgtttcca acgatttcgt
    41821 caacgactgt atcccacata aaggaaattt tttcattcgc aaatgcacgg tcttggatga
    41881 tcttttgtgc acgtaattca tctctacggt ggacgatgac tacttcagaa gcaaattgtg
    41941 tcaaatagat ggcttcttct actgctgagt ctcctcctcc gatcactact agacgtttgt
    42001 tacggaaaaa cgcaccatca caaactgcac agtaagaaac gccacgtcca gcaaattctt
    42061 cctcgccagg tacgcctaat ttacggtgga tacagcctgt tgcgataatg actgtttttc
    42121 cttcgtaagt tttatcttca caaataactt ctttgtggct gccgtgatcc ttgatatctt
    42181 gcacgattcc ataagcattt tctgtcccaa atcttgaaac accttcatac atcttataag
    42241 ctagatcagg acccatgatt gaatcgaaac caggatagtt ttcgatttct gccgtattat
    42301 tcatttggcc gccaggggcg ccttgttcga tcatcaatac ggataagttt gaacgtgaag
    42361 catataaagc agcagtcatc ccagcaggac ctgcgccaat aacgattaca tcatacatat
    42421 gtagattctc ctttacttaa tcaagtaagc atactttaca gccaatgcga aaaaaagtct
    42481 attgttctgc ttgcgtttct cgaatagctt tattatactc gaaaaatccg ctgaaaaaca
    42541 atagactttt ataaatcatt gattaatcat tcgaaagatt ttctccattt gaatcaatta
    42601 cttttttata ccagttgaat gatttcttct tcgaacgggc taatgtgcca tttccttcgt
    42661 tgtcacgatc gacataaatg aatccgtacc ttttcttcat ctcacctgta ccagctgata
    42721 ctaaatcaat acatccccaa gtcgtatagc ctaatagatc gactccatct aattctactg
    42781 catctttcat tgcctggata tgtgctgcca gatagtcgat tcgatagtca tcttccacat
    42841 aaccattctc atcgggcgta tcgactgcac ctaagccgtt ttctacaata aatagtggtt
    42901 tttgataacg atcataaata tcattcatcg ttattctcaa gcctaatgga tcaatttgcc
    42961 aaccccattc acttgcttcc agatatggat ttttgacaga agcaaagata tttcctgcag
    43021 tctgttccaa gagttcgttg tcagtagtcg aaactcgaga agaatagtaa gaaaaggaga
    43081 taaaatcaac agtatgttct ttcagcaatg cggcatcccc aggttccatt tcgatctgaa
    43141 tgccatttcg ttccatttct ttcaatgcat aagcgggata ttctcctcgt gactggacat
    43201 caatgaagaa ataattttct cgatctgatt ttctagaagc ccaaacatct tcaggattgc
    43261 aagtgtatgg ataatatgct cctgctgcca gcatacagcc tactttgttc tccggatcta
    43321 cttcatgagc aatcttcgtt gcgatggcac ttgcaaccaa ctcatgatgt gccgcttgat
    43381 atttgatttg ttcttcattt tctccttctt caaaatacag ccctgctccc atgaatggtg
    43441 catgaaggat catattgatc tcattgaatg tcagccaata tttgacaagt cctttatagc
    43501 gattgaagat gactcgacac agattttcat aaaaaccaac gagttctctg gaacgccacg
    43561 caccatattc tttgatcaaa tgcattggac aatcaaaatg cgtaatcgtc acaagtggct
    43621 caattccgtg cttttggcat tctttaaagg catcctcata aaatttcaag ccagcttcat
    43681 tcggctcttt ctcatccccc attggaaaaa tacgactcca ggcgatggac attcgataag
    43741 tcttgaaccc catttctgca aacaaagcaa tatcttcttt ataacgatga tacatatcga
    43801 ttgcaatttt tgctggataa aaatgatcct catcaaattc aaacattttt ttctttccgg
    43861 tgataacagg aaaacggtct tttccgattg gcacaacatc tacgtttgct agtccgcgtc
    43921 caccttcatc ataaccgccc tcacattgat tggctgctgt agcaccgccc cataaaaaat
    43981 cttttctgaa tcccattata cttcctccat tatatgtgta ttacctgata attctcttgc
    44041 cagttcatct tgaacttcga ttccttcttc ttttaatcgg ctgattgtct ccttgaattg
    44101 cggtaaatac tgctggtgtg caataaacaa ctcatccatg atccgttttg ctgtctttcc
    44161 tgatcgtata agtggattga tcgtaaacgc ctgtaaagct gtcccataat caccagtcac
    44221 agctgcttcg atcgtcagca attccatatt cttcattact tgcaaccagc ctctttcagc
    44281 agcaggaaga gaaccaaacg ctacatttct cgctccttgt gcgccaacat aggcagtgac
    44341 ttctactaca caatctgccg gcaggtcagg aacagctcca tcattctttg tagataccac
    44401 gatctgtgtt tctttatttc catagattga agcaatcgtt tcacaggcag cgtctgaata
    44461 ataagcgcca cctcgttttt gcaattgttc aggtttatgg tctaattctg gatctttgta
    44521 taattcaaat agctctgctt ctgtttcttt cacttgctgc gctcttgtac caatcgtttg
    44581 atattcttct aaagcatgtt ccagcatttc ttcttcacga tagtaatagc ggtggtagcc
    44641 acaagggatc atgttcattt gttttaattg ttctttgaaa aacgggatat caaagatatt
    44701 tttcggtaat ccattctctt catcgtataa acgatcaatc aattctgccg tgcggtcatt
    44761 tcctttatta tctgctactt tgtgccaatg gaaatgattt agaccggcaa acttgtagat
    44821 cagctcttct tttttcttgc caagcattgc tggttctgtc atcatcgcca tcactggcac
    44881 attgcataat ccaatcactt tatcccattt gccatatctg ataactgctt ctgtcaccat
    44941 cccacttggg ttcgcgaaat tgatcagcca agcatttgga cataaacgct tcatgtcctc
    45001 aacgattgcc aaaacgactg gaacggtacg aaaagctttg aatatcccgc cagcaccatt
    45061 tgtttcttgc ccaatcatcc cataataact agggatccgc tcgtctttga ttcgtgcatc
    45121 taattgaccg acacgaaact gagtcgtaac aaaatccgca tctttcaatg cttcttcccg
    45181 atccagagtt gcatagatct tgacttcata cggagaagca tcccacatac gctgagacat
    45241 ctgactaacg atctcaagct tttcttttcc ttcttctaca tctacgagcc agatttctcg
    45301 tatcggtaat tcctcatatc ttttgataaa tccttccatc aactcggggg tgtaactgct
    45361 gcctccacca atcgtagcga ttttgattcc ttttgccatg ttctcactcc tttacttttt
    45421 tacactttca ttatcttttt tgtaaacaaa acaaacaata gaaatctgtt tctttccagt
    45481 aacatttaca aaatttactg ttttctagtg gatttttgta aatatcttgt caaaaaatgt
    45541 ctattttaag ttatatagta taaatccgtt tacaaatcat tttcaaaaaa gttataattt
    45601 acgtaaaaaa ataagaagaa ggtatctaca tgttattacg tgaaaaaatc aaagaaatct
    45661 ccttttctcc ttcagaaaat gaagtgatcc agtttctctt aagcgattct ccagcacttg
    45721 gcgaaatgac catccaagcg attgctgagc gatgttatgt ccacccctct acactcatcc
    45781 gtgtagcaaa aaaaatgggt tttgatggct gggtcagttt tcgtaatgct tttttagctg
    45841 aaacagccta tcttgaaggg aattttcaag acgtagatgc gaatcttcct ttttccacca
    45901 cagacggtat tatgacgatc gcaaataaaa tggcttcttt agaacagatg acgattcatg
    45961 atacactttc tctcattcat catgaccaac tgcaaaaagc caaacaacta atgcttcaag
    46021 caaaaaaaat cgtgattttc gccagtaact cgaatacttt gatttctcaa gatttcatgc
    46081 tgaaaatgaa gcgcatcaaa atggatgtca cgattgtcac cacttttggt gaatcattct
    46141 atgaagcgta caattgcacg agtgatatgt gcgggattct gatttcttat acgggtgaaa
    46201 acaatgtgat ccttcgtacc gcagaaatat tgaaacaaaa tcatgttcca attttagctt
    46261 tgaccagtat cggtgattca acgctatctg caatgagtac agccgctttg cgacttacga
    46321 cacgcgagcg actgtattca aaaattggta attttacgat caatacatca atttgttatc
    46381 ttctagacgt gttatatagt tgtgtttttg cagaaaatta tcaacagaat ttagtccatc
    46441 taatttctgt cggtcaaaaa ttcgataaac gccctatcag ctcagccatc atgaaagagc
    46501 ctttcaattt tgaaaataaa gaagtggaat aaaaagaata gttaagccta gtccattctt
    46561 cacctaaccg ttcaggtcag tgcggtgata agtgcatcgt ctggcccgac cgtctcccct
    46621 tggttttcca aaatatccaa ataatccgtg taattggtga cgatcacagg tgtttctaaa
    46681 ctgtatcctt ccttttcgat tttctttttg tcgaagcgta gcaacagatc gccttgtttc
    46741 actctttatc cttgctgcac taagctttca aaatatttcc cttccaactg cacagtatcc
    46801 aatccgacat gaatcagcaa ttccagccct gtttcagaaa ccattccaat tgcctgtttc
    46861 gtcgggaaca gggtcatgac tgttccgtca aaaggggcac gtacttctcc tttttcaggg
    46921 tagatcaaga ttcctcgacc tagtgttcct tgtgcaaaag ctgcatcctt tgctgcattt
    46981 agtggagcga tttgtccttg tatcggtgtt tttacaattt ctttacctga ttttttctgt
    47041 atatcatctg tttcacctgc ttcatccttc caaaagaaaa aagtcagcgt aaaggatacc
    47101 accatcgcaa tggcgatccc aatcaataca ttaatcacat ctgttaaatc accatctggt
    47161 ctaatatagt tgggaattgt aaagatgcct agtccacctt gattccaaga agttaaattc
    47221 attaacccac tatacgcgcc ccctaacgca ccaccgacac aggtaaaaat aaatattttt
    47281 ttacgtggta atgtaaaccc ataaatagct ggctctgtaa tccccacaat accagaaaca
    47341 atggctggta ttgcaattgc tttgtctttt ggatttctaa gcttaaagta gagtgcggta
    47401 agtgctgcag tttgtccaaa agacactact gcaacaggtg tcataatatt ttgccaacca
    47461 ttcacagaaa attgcatcaa tcccattggt acgattgccc aatggagacc aaacatcacc
    47521 agaatttgcc agaagaagcc tacgattgct ccataaataa ctggcgaaag tgctaaaagt
    47581 gtttcaaatc cagccattaa aatatcagtt gcgaatgtga atactggtcc aacgagtaaa
    47641 aaacctaaag gcattgtaat aagaacggtg aagaatggaa cgaagaaatt cgcgatcatc
    47701 tcaggtacta actttttaat tggtttctga atttggctag ctaacaacac aataaagata
    47761 atgggaatga cagaagaagc gtagttacgc gcaatccagg gaatgccgaa tactgtttga
    47821 taaataggtg cttcaaaaat agtgccagaa aatatggtcg ttagtggtgc ttctgctgca
    47881 ccactcaaag cttccagcga caagctagga ttcattaatg ctgcgccaag caacatccct
    47941 acgaattcat ttactttaaa tttacgggca gctgttaaac cgataataac aggcataaat
    48001 tggaatacag aatcaccgat attatcaaac ataacaaatg tgccagaacc gcggtcaaac
    48061 gcgcctaaga agacaaggaa tgctgtcagt ccacgaatca tcccgccagc agctaggata
    48121 gcaaggaatg gctggaaaca gcccgatatt ccatcaataa gcatatcaaa cggtctcatt
    48181 ttttctgttg aaacagcctc atcaaaagta aggtttcctg cttttataac ctcttcaaac
    48241 acgactggca catgattccc aatgacaact tgatactgcc ctcccgctcg cattaccgtt
    48301 acaataccgt ccatattttt caagatctca tcatttgctt tttcttcgtt ttttaatttg
    48361 aaacgaagcc ttgtgataca atgtgtcaaa ccattgatat tttccttccc gccgacattt
    48421 tctacgattt ttctcgctaa ttcttggtat tttcccattt ctattccctc caatttatta
    48481 gtggaaggtt tagccaactg aatgtcacta cccttatttc atacgttctt gttaatttat
    48541 cctccttttt ttatttacaa cgattctcat gcactaaacg cgcagtatgg atcgttaaat
    48601 acattttttc gtccgtggac atctggtagt tgaacgtctc ggctaaaaag tctgctattt
    48661 tctcaacgca accaaacgta tccttatatt ttttttgaat aacctgaaac aattcctcag
    48721 aaacttctcc cacttctgat ttttctccat ctaggacgcg tgtcagaaaa aaacgtaagt
    48781 gtgtgacgaa tcgaaaaaaa tggactgaat cttcatcaaa tgtaatctta tagtaatagc
    48841 ggacgatatt tagaatatcc tgtattgtta tagtaaacag gtaggtattg tcttgctggc
    48901 tttgaatgcc ttgtgcattg actaaatgca atgcgataaa tccggcttca tcttctgata
    48961 acttgatgtg gtatttatcc gagattttct tcactgtttt tttcccgatg gcatactctt
    49021 taggaaatag ttgtttgata tcatacagca atacatttgg tacaaatatt cccattttgt
    49081 gacgttcgat agccgtatac aaatgatccg tcaatgcaat atacacagaa tcattcaact
    49141 ggacttgtag agcctctttt gtatattcaa tgatttcaca agaaatttct aagtactcaa
    49201 gaggaatcgc ttgtgccaat tcttggaact gttgtgaaag cccgtcattt gtcaactgaa
    49261 attttttgtc gatgcatgag tcaaaaatcg ggtcacccac tttctttttg aatgccaaac
    49321 cttttcccat cacgatcatt tcctgatttc tttcatccct ggttattacg acgttgttat
    49381 tcagtacttt ctcaatcagc atgttttgct cctttccatg atgtataggg ctgtatccaa
    49441 aacaaaaaga aaaacccaaa aagccgtcca tgaaaccatg ggagactcat caggtttagc
    49501 ttgcatcagg caatcactat ccaagttgta tcgttttctt tatattatcg aaagcaaatg
    49561 cttttgtcaa cgctttctta gtggctatta ggcacttctg actagctgtc gaatcttttt
    49621 ttaaatctgg tgactacgac actaactctc acagatgaaa aatatgagaa gctatgtttt
    49681 attttcactc tagtgcttag gtcaaaattc tactgtcaca acatctttta tataccactg
    49741 ctttgcagtt tgtacatatc tgcatacaaa ccattttgcg ctagaagtgt ttcatgattc
    49801 ccgcgttcta ctatatgacc tttgtctaaa actaaaatca attctgcatc tcgaatcgtt
    49861 gacagccgat gggcaatcgc aatcgttgtc cgtccttgac gcatttttgc caatccttct
    49921 tggatcaatc cttctgtttc agtatcgata tttgctgttg cttcatccaa tactagaatt
    49981 ttaggatcag tcacgattgt tcgcgcaaaa gtgatcagct gtcgttgtcc actagaatag
    50041 ctggcaccat gttcgatcac ttttgagtga tatccttttg gtaattcatc gatgaatttg
    50101 tttgcttgaa caaactcagc cgcatggcgt atctgttcgt ctgtgatagc tggattcatc
    50161 atccgaatat ttcctgcgat atccccataa aacaagaaag catcttgcaa gaccagcccc
    50221 attttcttac gtaactcttc cattggatat tctcgaatgt catgatcatc aatcaatatc
    50281 tgaccttcat aaaattcgta aaaccgcatc aatacgttga tgatcgagct ttttccgctt
    50341 ccggtgtgtc ccactaatgc aacggtctct cccggattag caacaaaaga gatattgttt
    50401 aatacattgt gctctccatc ataagaaaag cttacattgc gaaactcaat cttacctgaa
    50461 gtaatcattt gatctgctcc agggttttgt tgtggtgcat attcttccgt atccataatc
    50521 ttcaagatac gactaccagc aaccatccca tctgtgaaga tgctcaaaaa gtccatcatt
    50581 tgagacattg gattaaaaaa tccctggaca taggtcgtaa atgcatagat cagtccaact
    50641 tctacgggag aatgcaacgc atcgatccca aacaaagtca acaccaacgc aatcgccaat
    50701 gcatatagaa aattgatgat cggacttaac agaatcgaat tcgttttgat catcgcataa
    50761 cgcgtgtcta aatactcatt gttcacttgt tcaaattctt tagctaaacg agcttcttgg
    50821 cgaaactgct ggataatacg catgccggaa atcgattcat tcaatttcgt gttcagctga
    50881 cttaattttt cccgcatatt tcggtaaata cgagaactga atttctggta ataccagatg
    50941 acgattccta aaatcggcaa aaacaccaaa gtccacaagg caatttctcc attgatttga
    51001 aacatggcaa ggaatgaaga aacgactgca aagatcccag tcaataccat caaaaagacg
    51061 taccaaaatt caaatagcgt ttctgtgtca ttcgtcactc gagaaacggt tgatcctgcc
    51121 ggtgtctgat caaaataacg catacctagt gtatgcagct tttcaaataa ttttacccta
    51181 atatactgat aggtcttcaa tgaggccatg gaatacaaat accattggaa aaaccaaatg
    51241 atacttttta ctatgactcc aaataagtac ataccagcaa aaaacaaaat aacttgtgtc
    51301 gtagccgact gtttagccag atgatcatcc ataaaagttt ggatgatcct tggcaatagg
    51361 acattgatca cagacaaagc aaacgcaaat aagatagcaa cgatgaacgt tcttctaaaa
    51421 ggtttggcga acttcatcag tcgtttgatg atctttttct gttctttaag tggaatcgat
    51481 tttgtccatt ccgattgata attttcatcc atcaggcctc gcctccttct atcttcgctt
    51541 ctaattgctg tttctcccac atttgttcat accagccgcc tagtgcaagc agctcatgat
    51601 gggttcctcg ttcaatgatt ttcccttgat cgacaacaat gatttctttt gcatgcatca
    51661 cgctacttaa acggtgagct gcaatgatag ttgttttctc ttttcttatt tcttttaaat
    51721 tatgcaagat agcttcttct gttttggcat ctactgcaga gagtgcatca tctaatatta
    51781 ataattcagg atttttgatc aatgctcgag caatcgaaat cctttgtttc tgtccgccag
    51841 ataaagagac tccacgttct ccaactaagg tatcataacc ttttggtaat tccttgattt
    51901 cattgttgat aaatgctaaa gaagccgcat gctctacttc ttcttctgaa agttttggat
    51961 tagaaaaacg gatattatct cgaatggtca tcgaaaacaa gaagtgatcc tgaggcacat
    52021 agccgattga tcctaataaa gcattcaatg aatattcttt gatcgaacgt ccgccaaatt
    52081 ggattttccc ttgataatca tcgtattcac gcatcagtaa tttgatgatc gtcgtttttc
    52141 ccgcaccagt tttcccaaca atacctaatg tttctccttc ttggatcgca aacttgattt
    52201 gttctaatgc tggtgattct tctttcggat aattaaaaga ggaaatagct acattcagct
    52261 cgccttttgc cggggtctgc actgcaccca gttgttccac gatatgcgtc ttttcatgca
    52321 aaagttcatt gacgcgatca taagaagcat ttcctctttc caatacgttg aacaatcgac
    52381 caatcgcaaa catcggccaa acaagcatac cgatataact aataaatgag accatctgcc
    52441 cgatcgagat cgtgccttcc aagacatact ttccacctaa aataattgtt gcaacataag
    52501 acagaccgat aatcaaggta atgaatggat caaataagga gtctaaaaaa ttgactcgtt
    52561 tgtttttaat aattgcatct tcaatctttt cttcaaaatc cgctagatct tctttttctt
    52621 gtccaaatgt tttaatgact ttgatcccag tgatactttc ttgtgtctta tcattgatac
    52681 tagaaaaagc ttcttgcgaa tcacgaaaag catcatggag ttttgacccc agcactcgtg
    52741 aagtgacggc cagcaaaggc agaggaatca gcgcaatcag tgttaagcgc caatcaataa
    52801 acaaaatcat cgcaatgatc gttgttccgc ccgtaatcac tgaatctgca aaggtcaaga
    52861 taccagctcc tgctacattc tggatcgcat tcaaatcatt cgttgcgtga gccatcaaat
    52921 ccccagtccg atatttttgg taaaagagat tgtccatttc tgtaaaatgt ttgaataact
    52981 gctgccgaag ttctttctcc aatcgagctg cacttcccca aatattcgtc cgccagatat
    53041 aacgaaaaag atattgtaaa aaagcagcga taatcaatag gaagatccac ccgaaaatga
    53101 tctttattga taaattttta tcggcgatct catcaatgat gatcccaatc acttttggag
    53161 gaactaactg taccaaggcc actgcgaata gcgagaaaac cccaattaaa taatgtttct
    53221 tttcctgacg aaaaaaccag cctaattttc taaaaatcga cattttactc ctcctttgtc
    53281 tttatcaaga gcctaggatt gtctgtgctt gtcttttttg ctgaataatc tgaatagtct
    53341 aacaaattac gaaataaaaa acggactgaa aaaatcagcc cgtaaaaagt cgttgggtca
    53401 gaacctattt tttcccttgg ttcttcattt gctgcatcat ctggcgaatt ttcttctcag
    53461 atggtttttg ccccattgac atcatcattg atcgcaacat gtcctcatta acgggaggat
    53521 ttttttctaa atagtctttc atatatttac gcgctaggaa aaagccacct actgcgccga
    53581 ttagcaaagc aataatagca ataagtacga caatacctgt tgataacata taaatctctc
    53641 ctttctattt ccgaattgct ctcaatgact tattttacta aagtttattg aaaaaagaaa
    53701 ggcgtattct ttagtttcat gcaaaaaata gtggtttttt tagaggagaa caaaatttct
    53761 ttcgtcatct agcaagacgc gccatgaaaa aaaattaggc gtaccgaatc tttttcttta
    53821 attttttctt tttgaggtgt agaatgtaat cgtagataaa taggaaaggt ggttttttct
    53881 tgaataatca atccaataaa caatttcata agcatcgact tattgaacat acaaatggtt
    53941 tatctttagc tgaagtaaat ggaacagttg atgtaccaaa ggggaaaagt ttttttaaaa
    54001 cacttcttgc ttactctgga cctggtgcgt tagtagcagt tgggtatatg gacccgggta
    54061 actggtctac ttcgatcacc ggaggacaaa atttccaata tttattgatg tcagttattt
    54121 tgatgtctag tctgattgct atgcttttac agtatatggc agcaaaatta ggaatcgtga
    54181 gccaaatgga tttggcacag gcaatccgag cacgcacaag taagacatta ggtgtcattt
    54241 tatggatctt gactgaatta gccattatgg caacagatat tgcagaagtc attggtgcag
    54301 caatcgccct ctacttactt tttgatattc cattggtgat tgccgtcttt attactgtat
    54361 tagatgtttt cgttctctta ctactgacaa aagtcgggtt tcgtaagatc gaagcactgg
    54421 ttgtctgctt aattttcgtc attttattcg tttttgtcta tcaagttggc ttgtctaacc
    54481 cagattggca cagtttattt gctggcttta tccctaacag tcatacattc tcagactcac
    54541 cggtcatcgg cggcgaaact ccgctgactg gagctttagg gattattggt gcaacagtca
    54601 tgccgcataa cttatatctt cattcagcag tttcacaaac tcggaagatc gatcaccaaa
    54661 acgaagaaga tgtagcacaa gctgtacgtt tttctacttg ggattctaat atccagttgt
    54721 caatggcttt tctagtcaat gcactgctat tgatcatggg tgtcgctgtc ttcaaaaccg
    54781 gttctgtcca agatccttcc ttttttggtc tgtatgaagc tttatctgat ccatcagcta
    54841 tgagcaatgg tattttgatt gctgtagcaa aatctggtat cttgtccact ttatttgctg
    54901 tagcacttct tgcttctggc cagaactcta ctattactgg tacgttgacc ggtcaagtca
    54961 tcatggaagg attcatccat atgcgtatcc cgatttggct aagaagactg gtcacacgat
    55021 tgctttctgt gattcctgta ttgatttgtg ttttgtttac aagtacaaaa ggaacgatcg
    55081 aagaacatgc cgctttgaat aacttaatga atgaatccca ggtgttcttg gcttttgcgt
    55141 tgccgttttc gatgattcct ttactgatga tgaccaacag ccaagcggag atgggtagcc
    55201 gatttaaaaa ttcattcatc gtaaaacttc ttggctggtt ctctgtgatt agtctaactt
    55261 acttgaactt acgaggatta ccaggacaga tcgaaagttt cttcggcgag caagccactt
    55321 ccgctcaact agcattggct gatcacatcg cttatgtaat cattgttctt gtccttctcc
    55381 tgttggcatg gacgattggt gatttatata aaggaaacaa aaaatatgaa cagcttttgc
    55441 aggaaacggt agaagaaatc gaataaaaac tgatttttcc acacaaagac ccttgatagt
    55501 taggttaaaa atctagctac caagggtctt tttatttaga agataaagct tttttcagat
    55561 ttaatttact gaaaactagc atgcttgtta ctacgatgaa ttgcgttaat ggcacgcctg
    55621 caccagtgta gacacttaaa aaatagtcct ttttttctgg cgcataagaa caaaaccatg
    55681 agacaccgaa aagaaaaacc aattgtgtca gtattaatcc ggtgaccaca atcaaagagg
    55741 aactataata ggcacgatca gcttttgcaa atacggttcc tagtatcata agtaatatcc
    55801 ctgctattga agcaatcagc acgggaatag ccagaacttg gtaaattttt atgatgacat
    55861 tcgcgacttt tgctgatttt gttaattgga aattaggtgt tctcggttca ttactatcga
    55921 tccaattctc cattagcgga aggtttaata attcttgagc ctgtttgact tgttcttgcg
    55981 ttccgaaact ataatttcct ccttgatgga aatctttata tcgccatgca taagcgtatc
    56041 ctgattgaag gaaatcgaat acgattggca gatcactcat cgtctttcca tctcctgatc
    56101 ccatcagata gaactctttt ttctttttga ttgttccctt gtgataggct tcttctaatt
    56161 cttggttgac ttttttccaa aaatcattgg tttcttttgc attgttttgg taataaccag
    56221 attcgcttac cacatctcgc aatgcccaaa agatgatatc tccgggtaat tcttttactt
    56281 ttccaccttg agtccacgcg tgagtcgtat ataattcgtc aatacgggta gaaacagtat
    56341 ggaatgtagg agatgcggct aatgctttat ttagtgcagc atgtgagacc catatctcac
    56401 tgttttcttt attcaagttc gtttcatcat ctattcggat cagttgtttc atcaaacgtc
    56461 caaattctcc actggaacgg tcattgatgg ttgcaatacc gtatgttgtc tcatttttat
    56521 attcgatcca ttgatagacg atggaaaagc caactatagg aagtaaaaac aatgaaagtt
    56581 tcagccattc ccgtttcgag agaagaaaga gtcgtttttt taacttcttt acttctttga
    56641 aagaaaagtc ttgccctagc aagatctgga cgaaactgat acccaaagct actacagtaa
    56701 aaggaagaag ccagatagaa tcttcgcgaa tgaaccaaaa gaaaggaaaa gcgacagaaa
    56761 gccctaaaaa ccatggcagc aattttctgc tagaaccgta tttgcggtaa taaatagcta
    56821 ataaacaagc gataatgatc tcaacagccg gaatcacgag ggcattacga tatgttcgag
    56881 tggaatattc atgtgtaaaa ctaatcggag aaaacaaaaa ataaaaatag atacttaaaa
    56941 gaagatactt gttcttcaca atcggtttaa acgcgagtgc aaccaatata ctggcaaaaa
    57001 tactgaacat gccgaacaaa actgcataag aaagatgcag tttatgtgca agtactaaaa
    57061 ataagctgta ggagattcct ttggaaagtg ttgtagtcgt atactcccct agccatttac
    57121 cgtccaaaat attttgagca tagcgaatca gcagctggtc atcataggtt gccgacatgt
    57181 ctgttccata gattgcttta ctatataaat acaaacgaat aattgtaaat aatagggcta
    57241 tgccaagaat aaagtatgta tgtttctttt ttagttggtt gatcaagggt tttaaagtgt
    57301 tcagcatctt ttcgtccttc caatcacgtt ttgccacttg cttgtgaaac ttttcgtttt
    57361 tttacttttc taccagtata ccttgtttgt ctaaatttaa aaagaggggg gagaagatgc
    57421 atgatgaaaa agactgcaaa aagtactcct ttgtttctta aacaaaaaag gacaaggcaa
    57481 tgtgcctggt ccttttttgc tgctgtcaga tagaaaatct tagagtatca cttcttctgc
    57541 taataactca ggaaacactt ctggatcgaa tgtttgcgct ttgaacatgg cgatttcttt
    57601 tccatatggt gcgtaagctt tctttttatc tttgcctaca tagggagttt ccaagatttt
    57661 cgaaatattg tcaaacattg gatcatggac gatcttattc agcgtgtcga atccgattgt
    57721 tccaaaacca atattggcgt gccggtcttt atgcgaacct tgcggatttt tagaatcatt
    57781 gatatggagt actttaagcc gatctaaccc gatgatctta tcaaactctt ccattacacc
    57841 tgaaaagtct tctttaatat tataaccggc atcattcgta tgacaggtgt caaaagtaac
    57901 ggataatttt tcattcaatt ttactccatc gatgatttgc gctaattcct caaatgttcg
    57961 accgatttcc gtacctttac ctgccattgt ctccaaagcg atttgtgccg tctgttcttt
    58021 tgtcaaaact tcattcaagc cttcaataat tctagcaatt ccggcttctg ttcctgcccc
    58081 tacatgagca cctgggtgaa gtgtaatttg agtagcgcct aaagcttccg cacgaacaat
    58141 ctcttctctc agaaattgga cggcaaaagg aaacatttct ggtttgatcg tattccccaa
    58201 attaatgata taaggggcat gaacgacgat atttgttaga cctttttctg ccatgtacgc
    58261 ttttccggca tcaatattca tctcttcgat ggcttttctt ctagtgtttt gaggggcgcc
    58321 tgtatagatc ataaaagtcg aagatccata actggctgct tcttctgctg ctcctaacag
    58381 cattttcttt ccgctcatgc tgacgtgtga gcctaataac atggatggat tcctccttga
    58441 aaggcaattg ttactaacaa ttcctatata ttggtaagat gatatacaaa gaaaatgatt
    58501 gatttttctt tgccctgttc tccatagtaa ctgaaatttt ctctaaagaa aagcttaaga
    58561 actcttttat aataaagatc attttctcac gttttaactc ttttaaaaaa gaaattcctg
    58621 ccaaaaacag ccttgtctgt ttttttgttc tattatttgc tataattagc gaaataaaac
    58681 cattagttga ggtgaccctt ttgccacgca aaaatactcg aaaaaaacag aatagaagaa
    58741 aaaaagaaaa atggtttgtt cctaagatta tttttagagt ttttcaatca ttgactgttt
    58801 ttattactgt tcttcttttg atgttcgcag ctctaggtat tggaataggc gctggctatt
    58861 ttgcctatct cgtcgaagac acacaattgc cgactaaaaa agcactgcag acagaactag
    58921 gaaacattac agaaacgtca aagattgttt atgcagataa tacagagata tcaaaaatcc
    58981 agacagatct gatgcgcacg actatttcat ctgataagat ttcaccttta ttgaaaactg
    59041 caattatcag cacagaggat gaatacttcg ataaacacca aggttacgtt cctaaagctg
    59101 ttttacgagc attagtatct gaagctactg gtattggctc ttctggtgga tcaactttga
    59161 cacagcaatt agtcaaacag cagatcctta cagatgaaac aacattcaaa cgtaaagcaa
    59221 acgagatcat tctttctgca caagtagaaa aatacttttc aaaagatgag atcattgcta
    59281 cgtatttgaa tgtctcacca tttggtcgta ataataaggg acaaaacatt gctggagtcc
    59341 aggaagctgc aaaaggaatc tttggtgtag atgcaaaaga tgtgacgctg ccgcaagctg
    59401 cttatatcgc tggattaccc caaagcccga tcacgtatag tccatacacg aacacaggcg
    59461 cgctaaaaga agatctttct gccggccttg ccagaaaaga ttttgtttta ttcagtatgt
    59521 atcgtgaagg ccaaattacg aaagaacaat acgaagaagc aaaagcctat gaccttacaa
    59581 aagactttct accacaacaa atcgcagaac agactgacag agaattcttg tattatactg
    59641 tgatgaatga agcaacaaga atcattgcac aacaattggc tgaaaaagac aacgctgata
    59701 tgtctgattc atcggtcagt gacgcttatt atcaaaaggc acagcaaacg atccaaaata
    59761 aaggatatac aatccattcg acaatcgata aagatgtcta tgctgcattg caaaatggcg
    59821 ttgaaaatta tggatacatg ttagatgatg gtgctggcag tcaagtagaa accggaaatg
    59881 tattgatgga taacagaact ggccgcatct acggattcgt tggcggacgg aattacagtc
    59941 agaatcaaaa taaccatgcc ttcgatacag aacgtcaagc tggctcatca atcaaaccag
    60001 ttcttgttta tggacctgca atcgacatgg ggcttatcgg atcagaatcc cgtgtatcag
    60061 attatgcaac aacttggcaa gaaggagaaa atgctggcga gaaaatcgtc aatgctacta
    60121 acgaaggatc gaacaccttc caaaccgtcc gtgagtcact agaatggtcc aacaatatcc
    60181 cggcttatca cttatatcaa gatgtgttga attccggtgg atcgaaacaa tatgcttacg
    60241 agcactactt ggcaaagatg aactacccgg caaatgacaa ttggggcgtt gaatctgctc
    60301 ctttaggtac agtagatgtc acgacgcttc aacagaccaa cggatttcag gctttagcaa
    60361 acggcggcgt ctatgaagaa ggctatatca tcgattccat cacagataac gcaggaaatg
    60421 taatttataa acacgaaagc aactctgtcc ggatctattc ggaagcaacg gcatcgatca
    60481 tgaatgacat gatgcgtagt gtgatcaatg caaaaatcac tacaccattc aaagatgcca
    60541 tctcaagctt aaacggaaat ctaggaaaag cagattgggt cggaaaaact ggttctacca
    60601 atgaataccg agattcatgg ctaattgtct ctactccgtc tattaccatc agtagctggg
    60661 cagggcacga tgacaatact ggaatggaca gcaaagcaag gatacgttcg gctaattatc
    60721 ttgccaatct gatcaatcaa gcttaccaag caaaacctga catttttggc actgatgaga
    60781 aattcgaatt atcatctgat gtgatgaaga aaaaagtatc tggatttact ggtcaaacac
    60841 ctggaaaagt tactgtcaat aaaaaatcca tccaaacacc aggaaaaaca gttgaatcgc
    60901 tatgggcgaa aaatggaccg aagaaaagcg cctttaaatt tggcgttggc ggtaccgatg
    60961 aaaactatac agattactgg aacaccgctt cagcttatgc aagagcgaat caagcaacta
    61021 aagaatcaga tgagaaagat gattgattta atagaataca cagtaataag ggattgtgac
    61081 aatagtattg tcacagtccc ttattttttt gatggtggtg aacaaaatgc agcatctata
    61141 cacggattgt tttatatacg ataaatgtaa tttcaaccac tttctctctt ttttaagaca
    61201 caaaaaaagg attataacaa aattttgtca taaccccttt tcccaaataa acggtgttct
    61261 cctgccaact ccgaatcacg agtcacaata ttcatcaaac atgagatgct gttttttgaa
    61321 attgctcctt gtaacgcaga gttaaacggc aggcacacaa cctctgaatg gttgtccttt
    61381 tattattttg tagatccttt ttcttcgatt ccataaggca agataatcgt tttttcttcg
    61441 acttcttctt tattcatcat tttcgtcaat aggcgcatag ataccgcccc taaatcgtat
    61501 aatggttgtg tgatacttgt taaacgagga cgagctactt ctgtcagtag tgaattgtta
    61561 cttgtgatga tttcgaattc ttccggtact ttcacgccac ggtctaataa accatccaaa
    61621 ataccgatgg ctaattcatc atctgaaaca tagacagctg ttgcaccgct attatggatc
    61681 cgatcgacta gagatagacc atctttgaag ttgtattgtg cttcaaagat caatccttcg
    61741 ctatatggta ggttattttc gcttaatgct tctttatagc ctttcagacg attttgtcca
    61801 ttgatgggat cgatcaacgc accactgaca aaagcgattt ttttattgcc gctttttgcc
    61861 aatttgttta ctgcatcttt tgttgcggat acataatcaa tgtttacgct acctacttgt
    61921 tcatctggat caatagagcc agctaataca acaggagttt ttgaacgtga aaattctcca
    61981 cggatttcgt ctgtgatatg gtgacccatg aagatcacgc cgtccacttg cttagccagt
    62041 aagttattca atacattgac ttctttttgg tcgttgccat ctgaatttgc taagataata
    62101 ttgtatttgt acattgttgc cacatcatcg ataccacgtg ctaaagaagc aaagaacata
    62161 ttgctgacat cagggatgat tacaccaact gttgttgttt tcttacttgc caagccacgc
    62221 gcaactgcgt ttggacgata atccaagcga tcgataactt ccaagacttt ttttcttgtt
    62281 gctggtttaa cgtttggatt gccatttacg acacgtgaaa cagtagccat cgaaacattt
    62341 gcctctctcg ctacatcata gatagtgatt gtttgctttt ccatttgtgt tctcctattc
    62401 atattttata tgttttctga aaatacgtct tacatttcta aaatagaata tcaaataatc
    62461 tcaagaattg caaccgtttt atctctgttt tcatgaaaat ttttactttt ttcagttttt
    62521 agaacgttgg tcttttaata aatcagtggt acaattattg aatacaaaat taatttagaa
    62581 agtaggttgc caaatgaata acgtaaaaat caatgaacta cgtcaatgga tggcacaaca
    62641 ccaagtcgaa ttggcttata tcagcgaccc tggccacatc gcttactttt ccggatacga
    62701 aagtgatcct catgagcgtg tactagctct ttttatccct cttgaacaag atcctttcct
    62761 tttcactcct gctttggaag ttgaagatgc tcaaaacagt agttgggcgt atgatgtccg
    62821 tggctattta gacagcgaaa acccttggga gatcatcgga aaagaacttc gtgctcgcta
    62881 tggtcagcct ggcaatgtag ggattgaaaa gaacgccttg actgtcgagc gcttcgatgc
    62941 tatctctgat atcttgacgg gaacggattc ttacactgat ctaacttcca tcatccaacg
    63001 tctacaactg atcaaaactc tagaggaaaa agacaaactg atcgaagctg gtaaatgggc
    63061 cgatgttgca tttgagattg gctttaaagc agtgaaagaa ggcgtgactg aacaagcgat
    63121 cattgcagaa attgaatacc aattgaaaaa acaaggtgtt tcacaaatgt ctttcgacac
    63181 attagtcctt gcaggagcaa atgctgcaag ccctcatggt acaccaggaa atacgaagat
    63241 ttcaccgaat gaacttgtgt tattcgatct tggcgttgtt tggaatggct attgcagtga
    63301 tgctactcgt acaattgctt atcaaaaacc aaccgacttc caagaaaaaa tctacaacat
    63361 cactcttgaa gcacagcttg ccgcacaaga agccgtccgt ccaggtgtga cagcaggtga
    63421 acttgatcaa atcgcacgaa acgtgatcaa cagctatggc tacggcgaat atttcaatca
    63481 ccgtttaggt cacgggatcg gaacaaccgt ccacgaattc ccttcccttg tagaaggaaa
    63541 tgacttagta atcgaagaag ggatgtgctt ctctcttgaa ccaggaatct atattcctga
    63601 aaaagtaggg gtacgtatcg aagactgtgt atatgtgaca agcgatggct gtgtgccatt
    63661 cacgactaca ccaaaagaat tacttgtttt agaaaaataa gagtaaaaaa ggtgagagct
    63721 agtccgctcc caccttttta ttctataaat ttgtgatttt agtgatttgt agatgaatct
    63781 gtcattgtat cttttatttc ttttttagct tctttcgcat cttcttttgc cattttcatc
    63841 atttcttttg agtcatctgc aactggtttt gcttctgaca ttccttcatt gacagtatct
    63901 cctgctttac cagcagcgtc ttttacatca atcatgatat cttctgaagt atctttagca
    63961 atacttccta attcatctgc aggttttttc atatcttctg ccgttttttt gaaacgatta
    64021 gataagtcag ctgattgttc cttaagattt aacaagatat cgtcagattc acttcctgct
    64081 tcatctgctg attcacttac tttttgtttg acactacctg ctagatcacc tgcttgttga
    64141 gaaagatctt gcgctttttc ttttgcaata cctgttaact cagtcgattt ttctttcgcc
    64201 atatctgtgt aatctgaagc catatccatc aaatcatccg cttgggcagc taattcatcc
    64261 cgaagttctt taccagattt tggtgctaac aataacgcgg cgattgctgc ggctgtgcct
    64321 ccgactactg cacctaataa aaatccacct tttttagcca tttttatttt cctcctgtcg
    64381 tttcagtatg ttttttgttt ttaaaaaatt tcatcgctgt cccaccgact tttccggcaa
    64441 ccgtcgcttt agctgtcgtt ttaccgattc cgccgacttt cgtcgcgatg tttttactag
    64501 aatgattaag ttctgataca ctttcactta aatcagcaac tgctgtgaac aatggatcga
    64561 tcgttgcgac ttttccattg atatccaaga gcagttcatt acttttgacc agtaagcctt
    64621 ctacttgtct agacaaaaga tctacgtctt ttgtgacgat ttcgatcgtc gtatttgctt
    64681 ctgctacagt ctgatctact ttttctaaag ttttagaaac ttgcaacaac acacgaacga
    64741 taaaaacgac aagtatcgca aaggcgattg ctgcgatcaa tcctgcaatt tctcctcctg
    64801 acatgatcaa actcccttct tgtctctctt ttctataagg atagcatttt cgtgtttttt
    64861 aaacaaataa aaacgagctt caactacttt ttattcaatt agcagctgaa gctcgttaga
    64921 aaaaagggtt attttttctt ttcttctttg atttctgtta ttccttttgg attatgatcg
    64981 atcttgcttc cttctgcttc taatgtttta cctaaagaca ggatgtactc acgtaaaggt
    65041 gcacctactt ctggatgtgt tagaccatat tcaatacttg ttttcataaa accaaatttg
    65101 tcaccgacat cgtaacgttt acctgtgaat ttacgggcaa atacgcgttg tgttttattc
    65161 aatgtatcga ttgcgtcagt tagttggatt tcatttccgg ctcctggttg ttgctcggac
    65221 aatacatcaa aaatttctgg agtcaataag taacgtccaa taatagctaa atcacttggt
    65281 gctttgcttg gatctggttt ttcaacaaag tttttgacat tgtataaccc atcttccaat
    65341 acttctcctg gattgataat tccgtatttt gaagtttcat catgaggaac ttgcataacg
    65401 gcgatcgtag aagcatgagt acgttcgtaa tcatcgatta attgctgtgt caatggtact
    65461 tcgtcttcca ttatatcatc gcctagcata acgacaaatg gttcatttcc aataaaggct
    65521 cttgcttgaa gaacggcatg tcctaaaccc tttggatgag attgacggat gaaatgcaag
    65581 ttgacatctg tcgtttcttc tactaatttc aataattcgg tctttccttt ttcacttagg
    65641 tttgtttcta attcaatatt tgaatcaaag tgatcttcga ttggtcgttt agcttttcct
    65701 gtaacgatca agatgtcttc gatacctgat ttcaacgctt cttcaacgat gaactggatt
    65761 gttggtttat caacaattgg caacatttcc tttgccatag cttttgttgc tggtaaaaat
    65821 cttgttccta atcctgctgc tggaataact gcttttttaa ctttcatata cattcgctcc
    65881 ttcaaaaaat tgttaatgag aattcatttt ctttttttcc atcacgtaac atgatttctt
    65941 ttgcggctgt tttgatttct ttttgttcat acagcacttc atagattgtt tgagtgatgg
    66001 gcatttcgat ttccatcatt tgggctagtt ccatcgctgc ttgggtagta ttcacacctt
    66061 caacgaccat tcccatattg gctagcacct cttctagggg ctgcccttgt cctaacaagt
    66121 tgcctgcgcg ccagttccta gaatgaacac ttgtgcaagt aacgactaga tcgcctattc
    66181 cgcttaatcc gataaaggtc agcgggttgg cacccattgc tacacctaaa cggctgatct
    66241 cagctaatcc gcgcgtcatg attgctgcct ttgcattatc gccaaaccct aagccgtgaa
    66301 tagcgccagc accaatagca ataatatttt tcaaagctgc ccccatctct acaccgatca
    66361 catcaggatt ggtatagatc cgaaaataat tattcatgaa cagctcttgt acatattttg
    66421 ctgcttttgc atctgtactt gcagctgtga tcgtagtgat gtcatgtttt gctacttctt
    66481 ctgcatggct tggtccagaa agaacaacaa cagcttttct tttttctgct gggatttcct
    66541 ctaacaagat gtcagagatc cttttatgtg ttccctgttc taatccttta cttgcatgga
    66601 tgatcactgg ctttgtattc aatttaggca ctagttcttt tgcaacagaa cgtattgctt
    66661 tcgttggaat gacgaatagc accgcatctg cgtcttttac tgcatcttcc atattggtga
    66721 atgcttggat ggaatcgggt agataatgat ctggtaaata acgttgattc gtgtgttggg
    66781 tgttgatttc ttctacttgt gaagcacgat gtccccaaat ccgaacgtca tgtccgtttt
    66841 cggcgaggac ttgtgccaaa gcagtacccc aagagcctgg tcctaaaacc gctactctat
    66901 aattcatttt accactcctg aaattttttt catttttaac gctctaaaaa tcagataatt
    66961 tgttgatttt ttcctaatga gcggtcataa tccggtaaat ttcctttttt tctgcgccaa
    67021 ataaatagaa tcaatgtacc gacaaataac acagcagata ataattgaga aatacggatc
    67081 acacctaaaa agtaaagact gtctgtacgt aatccttcaa taaagaaacg cccgaaacta
    67141 taccacatta gataacataa aaggacttcg ccttttttca aaaggtgtgg tttctttcgt
    67201 aaaaacaaaa gcaaaataaa tccaatcaaa ctccaaagtg attcataaag aaatgttggt
    67261 tgacgataga tcccttcgat atacatatta tcaatgatga attgcggtaa atgcagactt
    67321 tctaagaagc ttcgcgtcgt gtctggtcca tatgcttcgt ggttcatgaa atttccccaa
    67381 cgaccgattg cctgtgctaa taatacactt ggtgcagcga tatctaaaaa agtccacaaa
    67441 gaaataaaat gatatttagt aaaaaaatac agcgtgatcg cgcctgcaat cagtccgcca
    67501 taaatagcta agcctcctga acggatattg aatatttgga ttggatcagc tatatactgg
    67561 ggaagatcaa ataaaacata atataagcga gcgccaataa tggagatagg caatccccac
    67621 aacataaaat ctgtcacatc atctgctttt aatcctaccc gaacagcctc tctgctgcta
    67681 agccacatag cgataatgat acctgatacg atgatcaatg cataccagta gataggaatc
    67741 cctacaagct caaaagcaac tcgattgatt tgtgctaaca tattgtcact ccttgctagt
    67801 cgttgcctga gttttcttca atcaagcgac ttaatctttc ttcaaatgtt ttcgttgcgt
    67861 caaagcccat tgtacgtgca cggaaattca tcgcggctac ttcaatgatg attgcaacgt
    67921 ttcgtcctgt tttgacaggg atttttattt gtggaatgcc cacttccgcg atttcaacgg
    67981 tcgtgtcttc agagcccaga cggtcgtatt tcttatcttt tgcccatgct tccagataaa
    68041 cagccaactg gacttgcata gagccacgta ccgcactcgc accaaaaaga ttcattacat
    68101 caatgatccc gattcctcgg atttcaatca gatgttccag gattttaggc ggttctccga
    68161 tcaccgttaa ttcatcttgc tgataaacat ctactcgatc gtctgcgatc aatcgatggc
    68221 cgcgtttgat caactccaac gctgtttcac tttttcctat cccactgtca ccttgaatca
    68281 gtacacctaa tccgtaaaca tccactaaaa caccgtggac acttgttcga ggggcaaggc
    68341 gaccatctaa ataactggat aattctccta ataaacgaga agttgagatg ggagaacgca
    68401 gtacagctat cccattttca tttgctgcct ggatcatttc ttctggagct ggtaatcctc
    68461 ttgaaataat aaatgcgggc atatcttcac tacataatct tctcatgatg atcaaacgct
    68521 cttctgggat catccgttcc gcaaaactga tttctttact gccaaatagc tgtaaacgat
    68581 tatgggaata ataattaaaa taaccagtca actctagtcc tgggcgtgag atgtccccag
    68641 ttacgatgac acggtctaag cttttctcgt cgcctgtcac gatttccaaa gataattttt
    68701 tcactaattg gctaactttt acaacttctg acattcatgc tacctcattt ctattagagt
    68761 gttctctatc attttatcat tgtctagcca aaagtactac caattaa
//
LOCUS       DAXQKX010000007        68637 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.007, whole genome shotgun sequence.
ACCESSION   DAXQKX010000007 DAXQKX010000000
VERSION     DAXQKX010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 68637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68637
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.007"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..2153)
                     /gene="acm"
                     /locus_tag="ACF3MF_000504"
     CDS             complement(<1..2153)
                     /gene="acm"
                     /locus_tag="ACF3MF_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HFE3926531.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQK"
     gene            complement(2648..2947)
                     /locus_tag="ACF3MF_000505"
     CDS             complement(2648..2947)
                     /locus_tag="ACF3MF_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFE3926532.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            3298..3930
                     /locus_tag="ACF3MF_000506"
     CDS             3298..3930
                     /locus_tag="ACF3MF_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFE3926533.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            4053..4691
                     /locus_tag="ACF3MF_000507"
     CDS             4053..4691
                     /locus_tag="ACF3MF_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HFE3926534.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(4810..4882)
                     /locus_tag="ACF3MF_000508"
     tRNA            complement(4810..4882)
                     /locus_tag="ACF3MF_000508"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4847..4849),aa:Thr,seq:cgt)
     gene            5003..5245
                     /locus_tag="ACF3MF_000509"
     CDS             5003..5245
                     /locus_tag="ACF3MF_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926535.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            complement(5384..6013)
                     /gene="upp"
                     /locus_tag="ACF3MF_000510"
     CDS             complement(5384..6013)
                     /gene="upp"
                     /locus_tag="ACF3MF_000510"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HFE3926536.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(6147..7094)
                     /locus_tag="ACF3MF_000511"
     CDS             complement(6147..7094)
                     /locus_tag="ACF3MF_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase fold domain-containing
                     protein"
                     /protein_id="HFE3926537.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            complement(7247..8491)
                     /gene="glyA"
                     /locus_tag="ACF3MF_000512"
     CDS             complement(7247..8491)
                     /gene="glyA"
                     /locus_tag="ACF3MF_000512"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HFE3926538.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            complement(8666..9691)
                     /locus_tag="ACF3MF_000513"
     CDS             complement(8666..9691)
                     /locus_tag="ACF3MF_000513"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HFE3926539.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            complement(9713..9892)
                     /locus_tag="ACF3MF_000514"
     CDS             complement(9713..9892)
                     /locus_tag="ACF3MF_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926540.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            complement(9885..10724)
                     /gene="prmC"
                     /locus_tag="ACF3MF_000515"
     CDS             complement(9885..10724)
                     /gene="prmC"
                     /locus_tag="ACF3MF_000515"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HFE3926541.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            complement(10717..11790)
                     /gene="prfA"
                     /locus_tag="ACF3MF_000516"
     CDS             complement(10717..11790)
                     /gene="prfA"
                     /locus_tag="ACF3MF_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HFE3926542.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            complement(11793..12377)
                     /locus_tag="ACF3MF_000517"
     CDS             complement(11793..12377)
                     /locus_tag="ACF3MF_000517"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HFE3926543.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            complement(12483..12731)
                     /locus_tag="ACF3MF_000518"
     CDS             complement(12483..12731)
                     /locus_tag="ACF3MF_000518"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF025054.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFE3926544.1"
                     /translation="MGIKKDYHHQGLGTKLFKEAEGYAAKHYKYLQVKTVDEGHYSIY
                     DQTICFYESLGFSRLEVFPNLWDEWNPCLVLVKKLEQK"
     gene            complement(12722..12952)
                     /locus_tag="ACF3MF_000519"
     CDS             complement(12722..12952)
                     /locus_tag="ACF3MF_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926545.1"
                     /translation="MPISFVKDREEKGKCVREILLDLPEWFGLPESTEKYIEESSKLP
                     LWCEKRKEEYLGFITLSQTSEDTAEIYSIVWE"
     gene            13058..13660
                     /locus_tag="ACF3MF_000520"
     CDS             13058..13660
                     /locus_tag="ACF3MF_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HFE3926546.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            complement(13764..14333)
                     /gene="lepB"
                     /locus_tag="ACF3MF_000521"
     CDS             complement(13764..14333)
                     /gene="lepB"
                     /locus_tag="ACF3MF_000521"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFE3926547.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(14563..15330)
                     /locus_tag="ACF3MF_000522"
     CDS             complement(14563..15330)
                     /locus_tag="ACF3MF_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6681 family protein"
                     /protein_id="HFE3926548.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEELVVYSRSQRRRHS"
     gene            complement(15327..15806)
                     /locus_tag="ACF3MF_000523"
     CDS             complement(15327..15806)
                     /locus_tag="ACF3MF_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HFE3926549.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            complement(15931..16668)
                     /locus_tag="ACF3MF_000524"
     CDS             complement(15931..16668)
                     /locus_tag="ACF3MF_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HFE3926550.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            16829..18229
                     /locus_tag="ACF3MF_000525"
     CDS             16829..18229
                     /locus_tag="ACF3MF_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HFE3926551.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            18452..19804
                     /locus_tag="ACF3MF_000526"
     CDS             18452..19804
                     /locus_tag="ACF3MF_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurT ligase domain-containing protein"
                     /protein_id="HFE3926552.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            19797..20495
                     /locus_tag="ACF3MF_000527"
     CDS             19797..20495
                     /locus_tag="ACF3MF_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HFE3926553.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(20557..21708)
                     /locus_tag="ACF3MF_000528"
     CDS             complement(20557..21708)
                     /locus_tag="ACF3MF_000528"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HFE3926554.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(21721..22158)
                     /locus_tag="ACF3MF_000529"
     CDS             complement(21721..22158)
                     /locus_tag="ACF3MF_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFE3926555.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            complement(22173..23939)
                     /locus_tag="ACF3MF_000530"
     CDS             complement(22173..23939)
                     /locus_tag="ACF3MF_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol-specific transporter subunit IIBC"
                     /protein_id="HFE3926556.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            24203..24880
                     /locus_tag="ACF3MF_000531"
     CDS             24203..24880
                     /locus_tag="ACF3MF_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFE3926557.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            24883..26010
                     /locus_tag="ACF3MF_000532"
     CDS             24883..26010
                     /locus_tag="ACF3MF_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFE3926558.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(26210..26650)
                     /locus_tag="ACF3MF_000533"
     CDS             complement(26210..26650)
                     /locus_tag="ACF3MF_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFE3926559.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(26661..28694)
                     /locus_tag="ACF3MF_000534"
     CDS             complement(26661..28694)
                     /locus_tag="ACF3MF_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HFE3926560.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            complement(28696..30399)
                     /locus_tag="ACF3MF_000535"
     CDS             complement(28696..30399)
                     /locus_tag="ACF3MF_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFE3926561.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            complement(30493..31443)
                     /gene="manA"
                     /locus_tag="ACF3MF_000536"
     CDS             complement(30493..31443)
                     /gene="manA"
                     /locus_tag="ACF3MF_000536"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HFE3926562.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            complement(31482..32507)
                     /locus_tag="ACF3MF_000537"
     CDS             complement(31482..32507)
                     /locus_tag="ACF3MF_000537"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFE3926563.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            complement(32716..33585)
                     /locus_tag="ACF3MF_000538"
     CDS             complement(32716..33585)
                     /locus_tag="ACF3MF_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFE3926564.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            complement(34289..36181)
                     /locus_tag="ACF3MF_000539"
     CDS             complement(34289..36181)
                     /locus_tag="ACF3MF_000539"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3926565.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(36178..37905)
                     /locus_tag="ACF3MF_000540"
     CDS             complement(36178..37905)
                     /locus_tag="ACF3MF_000540"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3926566.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(37921..38571)
                     /locus_tag="ACF3MF_000541"
     CDS             complement(37921..38571)
                     /locus_tag="ACF3MF_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HFE3926567.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            38775..39071
                     /locus_tag="ACF3MF_000542"
     CDS             38775..39071
                     /locus_tag="ACF3MF_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFE3926568.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            39263..39883
                     /locus_tag="ACF3MF_000543"
     CDS             39263..39883
                     /locus_tag="ACF3MF_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFE3926569.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(39975..41141)
                     /locus_tag="ACF3MF_000544"
     CDS             complement(39975..41141)
                     /locus_tag="ACF3MF_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFE3926570.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(41153..41506)
                     /locus_tag="ACF3MF_000545"
     CDS             complement(41153..41506)
                     /locus_tag="ACF3MF_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HFE3926571.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            41634..42656
                     /locus_tag="ACF3MF_000546"
     CDS             41634..42656
                     /locus_tag="ACF3MF_000546"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HFE3926572.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            42675..42836
                     /locus_tag="ACF3MF_000547"
     CDS             42675..42836
                     /locus_tag="ACF3MF_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926573.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(43095..43529)
                     /locus_tag="ACF3MF_000548"
     CDS             complement(43095..43529)
                     /locus_tag="ACF3MF_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926574.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(43639..45498)
                     /locus_tag="ACF3MF_000549"
     CDS             complement(43639..45498)
                     /locus_tag="ACF3MF_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFE3926575.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            45499..45639
                     /locus_tag="ACF3MF_000550"
     CDS             45499..45639
                     /locus_tag="ACF3MF_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoglycerate dehydrogenase"
                     /protein_id="HFE3926576.1"
                     /translation="MLAPSFLSIKECCFSYFSCTKFESKERKEELMKSKYSLSLWPFW
                     FL"
     gene            complement(45616..46775)
                     /locus_tag="ACF3MF_000551"
                     /pseudo
     CDS             complement(45616..46775)
                     /locus_tag="ACF3MF_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
     gene            complement(47082..48506)
                     /gene="araA"
                     /locus_tag="ACF3MF_000552"
     CDS             complement(47082..48506)
                     /gene="araA"
                     /locus_tag="ACF3MF_000552"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008733 - L-arabinose isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HFE3926577.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(48522..49220)
                     /locus_tag="ACF3MF_000553"
     CDS             complement(48522..49220)
                     /locus_tag="ACF3MF_000553"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFE3926578.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(49177..50838)
                     /locus_tag="ACF3MF_000554"
     CDS             complement(49177..50838)
                     /locus_tag="ACF3MF_000554"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004856 - D-xylulokinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0005998 - xylulose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HFE3926579.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            51056..52456
                     /locus_tag="ACF3MF_000555"
     CDS             51056..52456
                     /locus_tag="ACF3MF_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0051119 - sugar transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HFE3926580.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(52708..53787)
                     /locus_tag="ACF3MF_000556"
     CDS             complement(52708..53787)
                     /locus_tag="ACF3MF_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFE3926581.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(53873..54832)
                     /locus_tag="ACF3MF_000557"
     CDS             complement(53873..54832)
                     /locus_tag="ACF3MF_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HFE3926582.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(54844..56355)
                     /locus_tag="ACF3MF_000558"
     CDS             complement(54844..56355)
                     /locus_tag="ACF3MF_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046556 - alpha-L-arabinofuranosidase
                     activity [Evidence IEA];
                     GO_process: GO:0046373 - L-arabinose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-arabinofuranosidase C-terminal
                     domain-containing protein"
                     /protein_id="HFE3926583.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(56377..56940)
                     /locus_tag="ACF3MF_000559"
     CDS             complement(56377..56940)
                     /locus_tag="ACF3MF_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFE3926584.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(56946..57809)
                     /locus_tag="ACF3MF_000560"
     CDS             complement(56946..57809)
                     /locus_tag="ACF3MF_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFE3926585.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(57823..58719)
                     /locus_tag="ACF3MF_000561"
     CDS             complement(57823..58719)
                     /locus_tag="ACF3MF_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFE3926586.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(58894..60183)
                     /locus_tag="ACF3MF_000562"
     CDS             complement(58894..60183)
                     /locus_tag="ACF3MF_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFE3926587.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(60155..61672)
                     /locus_tag="ACF3MF_000563"
     CDS             complement(60155..61672)
                     /locus_tag="ACF3MF_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HFE3926588.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            61870..62760
                     /locus_tag="ACF3MF_000564"
     CDS             61870..62760
                     /locus_tag="ACF3MF_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HFE3926589.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(62833..63657)
                     /gene="nadE"
                     /locus_tag="ACF3MF_000565"
     CDS             complement(62833..63657)
                     /gene="nadE"
                     /locus_tag="ACF3MF_000565"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HFE3926590.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(63669..65141)
                     /locus_tag="ACF3MF_000566"
     CDS             complement(63669..65141)
                     /locus_tag="ACF3MF_000566"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HFE3926591.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(65778..66140)
                     /locus_tag="ACF3MF_000567"
     CDS             complement(65778..66140)
                     /locus_tag="ACF3MF_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HFE3926592.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            66363..67115
                     /locus_tag="ACF3MF_000568"
     CDS             66363..67115
                     /locus_tag="ACF3MF_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFE3926593.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(67255..68178)
                     /locus_tag="ACF3MF_000569"
     CDS             complement(67255..68178)
                     /locus_tag="ACF3MF_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFE3926594.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(68193..68465)
                     /locus_tag="ACF3MF_000570"
     CDS             complement(68193..68465)
                     /locus_tag="ACF3MF_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926595.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        19812 a        14015 c        11845 g        22965 t
ORIGIN      
        1 tatttttgta agaatatccc agcacagata gttactatca ataaaccaat gattacagca
       61 aaactagatt ttttactact tgttttagga agaatgcttt ttgatttatt tgttatctgt
      121 ttaggtacag ctctcttact aatataattg cttctttgtt cgctggattc tcctgtatga
      181 gcaaatattt gcaatttttg agagaataga tttctaattt tctctctctc tgtcttctct
      241 ggaaaatttt tccacggtgt tatatggcta cctggtatag atatatttgt tttttccggt
      301 gtataactgt ttttgatgtt atacccgtca atcgtcgtac tgtattcggg cacgttgtct
      361 tccgttacag tatagatgat ttcttgcccg tctctgtatt ttggcagatt tgtgaaacga
      421 tagcgccaat catctttttc acttacttct ttgtgttgga tcggttgacc gtcggctaat
      481 agatttactg tgatcgtcgt cggtcgtttg ccgtcttggt tctcattgtc ttcccatgtt
      541 ttttgtcctg agactgaaat gacttcttta ttctcatttg taacgactag cccgttttca
      601 attttttgat aacctgaagg gacataatca tttccgtttt gatctacttc ttgcacttta
      661 aacgtatatt cgtttccact atcatcatac tgttggatat cttcccaagt cactgaagtt
      721 attccattgt ctaatcgttt tgtttctgca tcaggaactg gttcccaatt gtttgtactt
      781 gctctgaata atttaaaata aatactcggt cttggagtgg ttccaccgtt ccaaatttta
      841 gttgctgtga tgttcgtaac ctttttcttg ttataaatag gtaaactgac tccctctgta
      901 tcattttcgt ttatggagaa tttgagttca tttgaactta gtggatcaaa atcaatccaa
      961 ttgggtgctt ctttttcttt tacaacatag tctcctactt gcaggccttt gatactagct
     1021 tctccctgtt cattcgaagt caacaggata ctagactgtc cttgaatagg ctgttcatct
     1081 gctcgtctta attcgaaagt cacatttggg ataccaatct ctgtgtcatt gatatatttg
     1141 aaaatcttca attcgcctct aactgtaccg ttgactccac cagaagctga aatattttta
     1201 actgtatgat tgaaactttc tccatcaaca gcaggtttat taaattcttt aaaccaagct
     1261 tccgaatgat tctcaaaatt tatttgttct gggttttcta tgatcgtctt ataactcacc
     1321 attattttcc taagattgac aaagtttttt ggtatagtta tttcaatgta attatcagtt
     1381 actgaaaaat taaatgtagc gctggggaaa tcttgtaaaa attgttggat tccctcttct
     1441 cctctataaa ccttctgttc acctaagtgt atttgattaa tttcaaacgt acttggatct
     1501 aatctttgtc cactttggat ttcatcactg attttaactg gttgttcaac ataagtgccg
     1561 ttattgttaa tattcaaaaa ccatcgaatg tgcttagtat cttcaggtag catgtctcct
     1621 gttttataat aaaaaacgct agaagaagaa ccagaagctg gctttgtcac atttacagta
     1681 gctgttttat caccgctcgt cacggtgaat ggtcccgtat tttcttcacc ggtatcggtt
     1741 acgtttctgg cctgtatctc aaattgcccc caaccttcta ctgagtctag gtttttaata
     1801 ttttcattaa acacaacctg cgcagaatct tttctgaccg ttaaagttcc aacattttta
     1861 ttttcaatca ttaatgggat ttctttttgg aatccttcac cgcgaatatt tccttcactt
     1921 ggccaattga tccaaagata atcacctggt tggatatttt gttttttttc gtcaaacgag
     1981 aattttactt ttatgtttcc tccatctgta atattcgttg ggtccacggt caacgaagtg
     2041 acattactgc tgatatctct gcctgcatcc gcatagacat gaacaggaat cagtgatgtt
     2101 atattagtaa taataaataa cattgataaa ataatatttc tacacttttt cattttttct
     2161 atctccccta ttttaactaa aaataaaacc tactatatca tctctcaaaa atcctttctt
     2221 caattcctcc cccactcatt tccaatcttt taactaaaaa attgatagtt attttacaaa
     2281 tatttataaa aaataaatat gccaaaaaac tgtttttaca aggtttttcc taatgtaaat
     2341 tattttttcg catatattca ttttatttta cttattgctt tcattttttc aatctatatt
     2401 tccaattttt aacttacaaa aatgcaacat taataaataa cgatagtttc ataaaataca
     2461 cttttaatta acattattag tttatactag ctgtttttgt gttaattaaa ggataaaata
     2521 caatataaag aaacatctgt ttctttattt agaataaaaa aatacagact ctgttcaaat
     2581 aaatgaacct agcctgcatt atgagattga ctatactttt taattcattg agatgaataa
     2641 ctcgttttta taaatgccca aaagtaatcg gtgccgaagc cattcctcga cctaattctt
     2701 tttcaaattt tcctattgtt gatatctcca tataaaacgg tgatactggt ttagacaatt
     2761 ctcccctgat tgctaacgga cgtaaactac gttccaaatt atttatgact ttaggataat
     2821 actgaccttt ttctaagcct gtctttgcgt ctatcaaaag tatacgttcc ttttctttga
     2881 tctctggatt taaaacgaga tcatataatt ttagtaccat gttttctatt tcttcacttt
     2941 tagacatcac gatttcctcc caaaaatata tttcttccca ctacattcta taaacaaagt
     3001 atacgctaca tctagatttt tttaaatcat tactggattg ttaaaacctt tcaatacact
     3061 gttatggcaa cgatttttat tttaaaaaca ttctaaatta aatcagtaaa aatttttatt
     3121 ctaagatttt tattagaatt acgcctaatt tgtgtctctc agggcaattc taagaacgtt
     3181 tcaagagata gcgacactat cgttatcgaa aaaggcgaaa acctatctca ttttctgcta
     3241 atgtaagttg gtttagcttt tgttaatatg actttatgaa aatggaggta attaaatatg
     3301 atttttccta aagttaatga agcaagcttg aataaaggat ccttttttca tatctatgaa
     3361 aacgaagatt ttgaactgta taatatcctt tcacaaaaag aggtcatcga aaaccaaata
     3421 atctgccatc caattattta caaatctatt ttcaagtatg cattttttgc ttccaatgat
     3481 tttcaaagaa tggagattac cgactgtata ttcgaaaact gtgatttttc aggctgtata
     3541 ttgacaaaaa gcatgttgca tcgcgtgaaa tttgtcaatt gtaaattaac aggtactaaa
     3601 ttgatggaaa gttatattgg gaacacgtta ttcgagaatt gtaaaatgga ctatgtaaat
     3661 ttatctggtt caaacataaa agaaagtacc tttgagcact ctgtcttatc aagcgcagat
     3721 tttgtagact gttccctcac taaaataatg ttttctacta atgatttaga aaatgctagc
     3781 ttttttgata ctgatttaaa aaatatcgat ttaagtagca actcctttga aatgattgaa
     3841 gtacgctcgg aacatctaaa aaattgtacg cttaatcagt tgcaagcact tggttttgct
     3901 agaaaatttt tacaaataaa agtagtataa tcaaaatgaa tatataagat aaatttttag
     3961 caatacaaat atccataaaa aaacattgcc tattttaact cttcatgtat actgactcta
     4021 tcttcaaaaa ctgaatagta ggagttatta tcatgaataa cattttagga aaaaaaatag
     4081 aacttaaaaa agggatattg ggcactattg tcgttgtact cggtttgtta gggttgctat
     4141 ttgcgccatc cattattagc attttttctt taactatcac tggatttata gcatttacac
     4201 ttgtttttgg taaaaaagat acgaaaaaaa tgttctcgaa acctgtcgct cctgtcaaaa
     4261 atatagccaa atattttttt atcaatgtag taatcagtgc cgcagtctcg gtatttttgc
     4321 aacaaatttt gaaatggggt ttaacaggca atccaataaa tgaggctttc agcccgttat
     4381 tatttattat tttgcctatc atgatacttg gagaagaatt gttctcagtg tattttctcg
     4441 ctattttttc tagtaagttc agcattcctg tcgctagttt cttgtcagca atcatctttg
     4501 gatttatcca ttacagtact tatgataatg gaaatatttt acacactgta gcacacatcc
     4561 ttttgataca aggggtggca agattgttat tcaaccaagc tgccattaaa agcaactcga
     4621 tcattacaag ttgggcagtt catgtgatat ttgatttcac agctatattg ctagtcgttt
     4681 tattctccta aatttttata gaaataatac atgctctatt gctaagaaag catactttat
     4741 ttcctttaaa caaaaagaca gatgtatcaa tggattaaaa atccttgata tatctgtctt
     4801 ctcttttaat gccagctata gggatcgaac ctacgaccta cgcgttacga gtgcgttgct
     4861 ctaccaactg agctaagctg gccttatcca aaagaaatta tatactctat ttggctgatt
     4921 gtaaagagtc cgatggaaaa ttagtttaat ttcatgatat ttttcataaa acgtggtata
     4981 attgatgtga aaggcaggtt ttatgaaaat ggcaactttt ggaaaatttg atacaactat
     5041 cgtaccatcg gaaattggtg aaaaattcaa gatcaatact cacgtaatgt tcacaattca
     5101 cggcaagtcg caaactggaa cgatttcaaa gcaattgaaa aattccgctg ttgttgagat
     5161 tgatgaaact gcagaaaatg cgaacttgat gacgcaaagt aagggtgtag taatcgttaa
     5221 ctacaaagaa ctaaaaaaga tttgaatttg accatctctg catttttggg atggtttttt
     5281 tatatgcaaa cgaaagctgt gaaaaagctg ttctgcatca aacgttaaaa atgaccaaaa
     5341 aaggatgtga caaaagttgt gtcacaccct ttttcgtatt tacttatttt gtaccaaaca
     5401 aacggtcacc cgcatcccct agtccaggaa cgatataacc atgttcattc aatttttcat
     5461 ctagagaagc tgtatagatg tcaatatcag gatgcgcttc ttgcaaagct tttactccct
     5521 caggtgctgc taccaaacaa acaaatttaa tgttcgacgc gccacgttct ttcaatgcat
     5581 cgattgccat gattgctgat ccgcctgttg ccaacattgg atctactaca aacaactgac
     5641 gtgcatcaat gtcttctgga agtttgacga aatattcatg tggttccaat gtttcttcat
     5701 ctcgataaag accgatatgt cccactttag cagctggaat caattccaag ataccgtcaa
     5761 ccattccaat acctgcgcgc aagattggaa taatcgctac ttttttacca gacaacgttt
     5821 tttgtgttgt ttcagtgatc ggtgtttcga tcacgatgtc ttccaatggc atatcccgtg
     5881 atacttcata tgccatcaac atagcgattt catcgactac ttcacgaaaa acctttgttc
     5941 cgcagttttt gtcccgaata atagttagtt tgtgttgaat caatggatga tcgatcactt
     6001 gaaatttgcc cattttttaa gctctccttt gttctgtcgt ttctttttaa ttgtaaaaca
     6061 aaatcaagtg attgactagt caaactcgcc atttttccta agaaaatccg tttttgaaaa
     6121 gaagttttcc tgcggacaag caaagcttat tcttttttct tgatccaaga agtagataat
     6181 gccattgctg cacgcgttgc ctttgtctga tccatagcat ttaccatgac aaaatcatgg
     6241 atgattcctt ggaagcgtac ttgtgtaaca ggaacccctg catcacgaag tttgcgcgca
     6301 taagcctcac cttcatctct taatacatcc gcttctcccg ttaaaatcat tgctgaagga
     6361 agatcattta gttcatttat atttgctctc aaaggcgaag ctgtgatttc agcacgctct
     6421 tcttcattcg tcgtatattg gtcccaaaac cacatcattc cttctcttgt caaaaaatag
     6481 ttttctccga attcatgata ggaatctgta tcaaaatcag cgtttgtgac tggataatac
     6541 agcaattgct tggatattgg gaggcccttt cgttcttttg ttaagatcgt catgactgta
     6601 gccatgttac cacctactga atctcctgca acgattagat tctcgagatc cagatttttt
     6661 gacttggcta atttattcag ctgttgcaac acagcataat tttgttcaat tgctgttgga
     6721 tattttgctt ctggtgatcg actatattct ggaaagacaa cgacggaatt cgtacgaacc
     6781 gcaagttctc tgatcaattt atcatgggtt tgagcactgc caaaaaccca gcctgctcca
     6841 tgaatataaa aaataactgg taatttatcc atattccctt ctggtcgtac gagacgaata
     6901 ttgagttttc cccattcgcc agtatccacc atcaagtctt caatatcgac ggaatatttg
     6961 ttcacaggtg attcttgtac ttcttctagt aaaactcttc cttcttccgg tgctagttca
     7021 tagatacgcg gatgaggcgc atttgcatca ctgaatgcta ctgcttcctt ttctaacgag
     7081 atacgatcag tcatgacttt tcctccctga gatttagtgt gaagactaaa attacacctc
     7141 atatactaga gagcatcacc gatattgtca aagaatccgt tttcccaaaa aataaacaga
     7201 aaagcccaac attgaacttt tctgtttact aatggaattt aaatttttat tttttatgca
     7261 acggaaattt ttcagttaat tcgcgtacac ctgttttgac ttcgtctagt tgagcgttat
     7321 catcttttgc ttgtaatgct ttgacaacta gttcagccac ttttacagca tcttcttctt
     7381 tgaacccgcg agtagtgatt gctggcgtgc cgattcgaat accgcttgtt ttgaatggac
     7441 ttagtgtttc aaaaggaatc gagtttttat ttacagtgat attcacactg tccaaaatgc
     7501 tctctgcttc ttttccattt atacctaact cgcgaacatc gatcaacatc agatgattat
     7561 ctgtcgcccc tgaaatgact ctggttccaa ttgcttgatt gaaaactttg accattgctt
     7621 ttgcattggc gatgatttgt tcactatatt ctttaaatgc aggatctaat gcttctttga
     7681 atgctactgc tttacccgca atcacatgct ctagagggcc gccttgaata ccaggaaata
     7741 ccgcactatt tatttttttt gctaatgctt catcgtttgt caaaatcatg ccgcctcgag
     7801 ggccacgcaa tgttttatga gtggtagtcg ttgtgatatc tgcataagga actggattag
     7861 gatgaagtcc tgctgctact aatcctgcga tatgtgccat atctaccatc agttttgcgc
     7921 ctacttcatc tgcgatttct ctgaatttcg caaagtcgat cgttcgtccg taagcactgg
     7981 cacctgctac gatcaatttt ggttgatgtt ttctagctaa aatacgtacc acattataat
     8041 caataacttc tgttgtcgga tcaacaccgt aagcaacaaa gtgataggtt ttgccactga
     8101 agttgactgg tgatccatgt gttagatgtc cgcctgcgga aagatccatt cctaagatcg
     8161 tgtcccctgg ttctaccaaa gcgagataag cagccgtgtt ggcttgagag ccggagtgag
     8221 gctggacgtt cgcaaatttc gctccgaata attcttttgc acggtcaatc gctaaatttt
     8281 caacgatatc gacaaattca cacccaccat aatagcgatg ccctggataa ccttctgcgt
     8341 atttatttgt caagatactt ccttgtgcag ccatcactgc ttcggagaca aagttttcag
     8401 aggcaatcag ctccaaatta tgttcttgtc tttcttcttc tttggcgatc gcagcccaaa
     8461 gatcagggtc aaacgttttg taatctacca caaacaacag ctccttttta ttttcctaca
     8521 attttatttt tcccatcaaa aacaaattgc caaatattcg tatctcttct attacgatta
     8581 gttacgctta gtttttcgtt cactgataga agatttactt gatagcattg tatcatacta
     8641 aaagaatgcg acaataacca attgatcatt tttcaaaata attttgtcct gctgcttttt
     8701 tcaagcgatt catgtaagca ttccccaatc cagtttctgg atacacttgt acaaaaatca
     8761 aatctaatcc aagtgttggt tcatctaatc ctcttagacc tgcaaacaat cctttagccg
     8821 ccgcttctac tgagttgtcg ttatacatat aaacagctgc agtatctgtc cgcacttgat
     8881 ccgcaatttc ggggcttgct atgacacctg cacggatctt cttatttttt gcccattgaa
     8941 ctgcagttga ccaatcgcca tctctgacca tcagaacacg tgtatcgggt gagtagtgtt
     9001 tgtatttcat cccaggggct tttggtgttt cattttcttt tacaagatgc tgatcaatag
     9061 caacaggaga ttcgatgact gcttcgattt gttctttcgt tactgcacct ggtcgtaaaa
     9121 tcataggcat ggctgttgga tcacttaaat caagaacagt ggattctaca ccaattcgcg
     9181 tagctccatc atcaataatc ccggtaattt ttccttgtag atcatgatat acatgatctg
     9241 cagtcgttgg acttggtttt cccgacgtat ttgcacttgg accgacaagc ggaacaccgg
     9301 aaagttcgat tacttctagt gtttttttgt tatccggtat acgaaatgca gctgtggata
     9361 atcctcccgt cacaactgag ggcaaagtgt cttttttgat cttaaatatc aaagttaatg
     9421 gtccaggcca gaagttcttc acaatcttct ctgctgccgg atgaaagttg tccacatact
     9481 cttttacttg ttcaaaagag gcgacatgga cgattaatgg attatcttgc ggtctccctt
     9541 ttacagaaaa cactttcttg acagcgtttg gtaaaagagc gttggcgccc aatccgtata
     9601 ctgtttcggt aggaaaagca acaagttctc cttctttcag tgcttcggct gcctcttgca
     9661 attctgtttc atcatatcgt ttcgtttcca cagtttatcc acaacccctt tttcatacat
     9721 tcttattttg tctgagttta tcctcaagtt ttccactgtt tgtggataat ctatttgtca
     9781 atagtggata aacttgttga taaaccaaaa agtcgtttac atccttgtca aataagtgtt
     9841 tttttataat aaaaaaacaa ataaaaaatt tttcatccac aacttcaacc ataaacttgg
     9901 atcattcgtt cattgccaaa aagatccttt tttatcgcca cttttttatc tggaaatgct
     9961 tgctgaaata ttttttttac tgcttcacct tggcgaaatc cgatttctaa aaaaatcttt
    10021 ccatttgatt ttagtacgct tggtgcttca actgctattt tttcataaat agctaatcca
    10081 tcgttctcag caaaaagggc cattttaggt tcgaatgacc ggacactttc atccatcagt
    10141 tcccattcat tccgactgat gtacggcgga ttagaaataa tcacatcaaa ttgctgatcc
    10201 attactggtc ctaatgtatc tccatgataa aaactgattt tcgttccttc tttctgagca
    10261 ttttctttcg ctacttctaa tgcttcttct gaaagatcca cagcagatat atgccaattt
    10321 tttcttgctg ctttcaaact aatagcaatt gctccagtcc ctgtcccaat atctatcact
    10381 tctaacggta caccaggcgt ctcgtctaaa caccattcga ctaactcctc tgtttctggt
    10441 cgagggatca gtgttgcttc agttaccttt aaccgatgat cataaaaatc tgcatatcct
    10501 agcaaatact gaggtggatg atctgcaagc agaagtcgca gatcggtttc gatcaaccgc
    10561 tgttcttctt ctgaaatctc ttcgttcata tgaaggagcc aatcaagttt tttccattgt
    10621 tttcgttcca aaaataaaaa ttggatacta tatgcttctt tcccatgatc ctctaaaaaa
    10681 gaagaagccc gtgacaggac ttctcgatag gtcattttac ccattttgca tagcttccag
    10741 ttttgatgtt tgatcataca tgatcaatgc atcaacgatc tcatctaatt tccctgctaa
    10801 aatctgatct aatttttgga tagttaatcc gatacgatga tcagtcacac gattttgcgg
    10861 gaaattatac gtccggatcc gttctgaacg atccccagtt ccgactgctg attttcgatt
    10921 ggcatcatac tcgctttgtg cttcttgctg gatcttatcg tacacacgag cacgcaagat
    10981 tttcattgct ttttcacggt tcttgatttg agaacgttca tcttgcatag caacaacgat
    11041 ccctgttggt aagtgagtca aacgtacagc agatgctgtt ttattgacgt gctgtccgcc
    11101 agcacctgaa gcatgataga tatctgtacg gatatctttg tcttcaatat cgatctctac
    11161 ttcttcagct tctggcatca cgacaactgt tgcggtggaa gtatggatac gcccttgcga
    11221 ttcagttgaa ggaacacgct ggacgcggtg cgcaccactt tcatatttta atttcgaata
    11281 tacgttgtct ccggtgatca tcatgatcac ttctttatat ccaccgattc cggtaacgtt
    11341 agcttccatc acttctgttt tccagccttg tgcttcagca tacttttggt acatattgaa
    11401 aagatcgcca gcgaataatg ctgcttcgtc tccgcctgct gctccacgga tttccatgat
    11461 gatattttta tcgtcatttg gatcttttgg taaaagcaag atcttgattt tttcttctaa
    11521 gacttctttt tcttttttta attcagataa ttcttctttt gctagttcag ccatttcatc
    11581 atccagtttt tcaccaagca gttcttctgt atcggtgatt ccttgtacta cttctttata
    11641 acgacgataa acttcgactg tttcgcgcgt gtttgcttct tcttttgaaa gctgcataaa
    11701 acgctttgta tcagaaatca cttctgggtc acttaaaagt tctccaagct cttcataacg
    11761 gtcttcaatt gcttgtaatt gatcgtacat gcttattctc cttctgtaat cattgatggg
    11821 tgaaagtaat gttttcgaca aacggggtaa taagcttcat ttccgccaat ttgcacttga
    11881 tcgccttcat aaacagggtt tccatcaata taatgtaaat tcatgattgc ttttttgtgg
    11941 cagaaccaac agattgtttt catttcttcg attttgtctg cataaagcaa taaatatttt
    12001 gatccttcaa ataactcgtt tcgaaaatca tttttcaaac caaatgccat aaccggaata
    12061 tccaattcgt ccacaattct cgtaaaagca atgacatgtt tcttttttaa gaattgcgct
    12121 tcatcgatca gcacacaata gggtttgctt tccattttct gaattacgtc aaatacgtct
    12181 gtttcttcaa atatcggcat cgcattacgt ttcagtccga ttcggcttga aacaacgcct
    12241 aaaccatctc ttgtatcaat accgcttgtc attaagacaa ctggcttatt ttgttcttca
    12301 taattatgtg cgacttttag gatctcgatc gtcttgccgc tattcattgc gccatactta
    12361 aaaaatagtt gtgccatgct ctttttcacc ttccagtttg ttcctatggt attatacttg
    12421 attttcagca ttttttacag tgagaatttt catcaagcac agattagtat taaatctatt
    12481 gctcactttt gttccaattt tttgacaaga actaaacatg ggttccattc atcccataaa
    12541 tttggaaaaa cttccaacct tgaaaatcct aatgattcgt agaaacaaat agtttgatca
    12601 tatatagagt agtgcccctc gtctacagtc ttcacttgca aatatttgta atgttttgct
    12661 gcgtaacctt ctgcttcttt aaaaagtttt gttcctaatc cttggtgatg atagtctttt
    12721 tttattccca tacaatagaa tagatttcgg cagtatcttc acttgtctgt gaaagagtga
    12781 taaagcctaa atattcttct tttctttttt cacaccataa aggtagttta cttgattcct
    12841 cgatatattt ttccgttgat tcaggaagcc caaaccactc aggcaagtct agtaatattt
    12901 ctcggacaca ctttcctttt tcctctctat cttttacaaa cgatatcggc atattctttc
    12961 tagattctcc ctttttgaat tgagtatagc atgctttctt tcttttcacg tgctataata
    13021 agttaaaatt tcaaagtttt acgtaaggag ctatttgatg acaaaaaata tttttgattc
    13081 catcgctaac cattatgatt cccctgaccg tcaagcatta gccaagatta ttcgcgaaga
    13141 actaactact tatctaccgc gcgacagcca ccaaaaagtc ctgctggatt acggaggcgg
    13201 aactgggctt gttagtttac cgcttgcgga aagattcaaa gaactgatca ttgccgatgc
    13261 ttcagaaact atgctgaaaa tggcagaaga aaagatccaa gcagcagatc tgaaaaatgt
    13321 ccgaacgatc cacgctgatg cttctgtcga atttcctgct gtccaagcta atctcatcct
    13381 tctatcactt gtacttttac acattcctga tacggagaat attcttacaa aactttatga
    13441 aattttagct cctggcggtc aattgatcat cgtagacttt gacaagaatg aacaaattag
    13501 tcatccgaaa gtccataatg gctttagcca agaagaattg aataatcgat tggaaaaaac
    13561 gggctttgtc tctgctacta gtcatacctt ccatcgtggg gaaaagctat ttatgaacaa
    13621 aaacgcttcg cttttcttat ccatcagcca aaaagcttaa aatgagattg caaaaaaagt
    13681 gagcaactcc aagaaataag aaggaatttt cggaaaaaga agctgtgaca aaaaacatgt
    13741 cacagcttct ttttattttt tcatcacatg attttaattt ctgaaagagg ccaataacgg
    13801 aaaacaactt ttccttggat catatctttg tcgactaacc caaacattcg gctgtctttt
    13861 gaaatcaagc ggttatcgcc tagaacaaga tactttcctt ttggcacagt atattcaaag
    13921 tcactcgtaa aggtggatga actttctgct tgtgcttgga atcctgagct ataagcatat
    13981 tctccttgta acttatcttc tgaaaattct tttttgaact catccagata aggttcatca
    14041 tactttttgc cattaatggt caactggtca ttttccatct tgactgtatc tccaggcata
    14101 ccgatgatcc gtttaacaat catccgttct tcatcccccg gttcctttgt agtaataata
    14161 tccattcgtt catagtttga gatcttagat gaaatcaatc gttgtccatc acttaatgta
    14221 gggtccatcg aatgcccgtt tacagtaact ggtgtaaaca cgtacactct agctaataaa
    14281 atagccgcta atacaaggat caaaatcccc caatttttca aaaattcttt cacagcttac
    14341 ctcctacttg tattttcctc gttatttatt acgttttttc acaatacttc gttgtacttt
    14401 ctttattcta caatgtttat aaatgaaagg aaagaataag tgatgtgttc gtcttatctt
    14461 tctcgttata taaaaaagga acgtgacaaa agacgtgtca catccccctt attccgaata
    14521 aacgttttta tcgcaaccac tgatacacgg cgtttcatca cattatgaat gtcttcttct
    14581 ttggctacga ctataaacca ctagttcttc ctgcgactgt gccttttttg caatcaattt
    14641 cagacgataa ggctcatgat agcgtaaccc gtctttgaca aaatcaccgc cgacgatgaa
    14701 caatccgaca ggttccaatg tgtcttctgt tgagtcaagt cgaatggtcc ctactttttc
    14761 catgtccgag tagcttcgtc caatatttag aacatactct ttctctcctg ttttcttgac
    14821 atagtaataa ggatacaatg tatttctatc gaccagaaat ccatccatgc gaccgagttc
    14881 atttgttttg atctcaccat ttccaatcaa ataccgcata ttctcggcta atttcaattg
    14941 ataatcttcg tcataagaaa ccatgacctc ttgtgtattc actttatcga tcgaatttcc
    15001 attatctatc gattcttctg tctggatgtt gaacgcttca tcaggtaaat acttcacaaa
    15061 aagctgagtg acatcggctt tcgtgttttt atctaaaaag taataaaata catttaaaac
    15121 agtaaaataa acaagcacta gaaatgcaag tccatataag aaaaattgaa gatagttttg
    15181 gttttgccaa agtccataaa caattctcaa taaataaagc gtgggaatca cacttaaaat
    15241 cgtatatcca cggttaagat atttaggact gatgtctaaa tagccaagga atttatgcac
    15301 cccgttgata aggtctagta aaaatgtcat tgagaatcac ctgcttgctg gttatacgtt
    15361 tgggtatttc ctgaatcttg gttttgctgt gctgtacgtg ctgcatcatc attttgcgtg
    15421 ttatcatcta cagtcgtact gcttggtatc gtttcggagc tagcacttgt atccggactt
    15481 gtacttggat tggttgaatc cgatggagtg ccatctggta ccgtattact tgtttcgctt
    15541 gagctgtcag ttgtatatgt ctcatcatac gacgaactag ttgttgtatc gtcccatgta
    15601 cttgtcgtag tggtttcatt caaactttcc gttgttgttg gttcagatgt cgagactgaa
    15661 gtagttggtg ttgtttcttc tacagtacta gaacttgaac ttggtgcacg gtagctggaa
    15721 ctattcacaa tacctgtagt agtcgcgaca atcgtcgaga ttgttaatac agcgattggc
    15781 ttcaaaatag gtgctacttt tcgcatctta tctcttcctt cattgaaatt tattcttgtt
    15841 tccttacttt actacggaca aattatacag tctaccttat ttctaccata aattctttat
    15901 ttttttctta cgtttttccg aaagatttct ttaattttcc tcaaaaacta cggttgatgt
    15961 ttttaagtaa gcttttgctt cccgattgat ttctttcaga tcgcatcctt gctgcttggc
    16021 agcgaacacg caaccacaat aacattggcg ataaatatca tactctttgc acatttgcaa
    16081 agagcgttca tagcctttgt ttttcttgaa atcacttggc aagtattgtg tcccgtaaat
    16141 cttttggata tccattccga tctgattgat caaagctgca tttttctttg gcgagatggt
    16201 cagggcactt ccaaagtaat cgtatcctag ttcttgcgct ttttgcgcaa caagatctaa
    16261 tcgcatattg aagcatgcac tgcagcgagc accaccttct ttttcgtttt caagatggtt
    16321 tgttaaaacc attttggtga attcatttgg acggtattca tcaacgatta gcgcaacatg
    16381 atggtcagtt ttctcattaa attggtctac aaatcgtttt tgttcatgta atcttcgcaa
    16441 atactcactt ttaggatgaa tattcgaatt tgaaaaaaat aacgtgatct ctgcatattg
    16501 agacatgaat tccaatgtgt gcgtactgca aggagcacag catgtatgta ttaatatctt
    16561 aggctttact tcttctttct cccattgcat gatcattttt ttcagaactg tatcataatt
    16621 tattttttga tttttcattt tttctacgat ttgttgagca ttaatcaatt tgttattcct
    16681 cctccttctt ttttctagga ttttccttat tataagccat ttctatttta atcgaaagct
    16741 gtattgttat ctgtttgata atttctttga gtattcctaa ttccccttgt atactggtag
    16801 aaacgactat tgtcaggagg atagtactgt gcatgttgat ttattctttc gaaggctgca
    16861 gcggcgagga cagaagtttg ctgccaatca tttctcatcg atccaaatca tcgtttttta
    16921 ttatatattg atgacggtct tatcactcgt tctattttat atgccgattt ttcgcgaacc
    16981 agatagccat gtttcttttg tggacatgct gttcatggca atcagtacag tgagtgtgac
    17041 tggactatcg acttttgata tcaattctgt gttcaatgat aacggtatta tactgctgga
    17101 aatattattt caagttggtg gtttggggat catgatgatt tctactgctt ttgtcatttt
    17161 ttctaaacga cggatcacac tgaaacagcg acagctgatc atgacggata tgaatcaacc
    17221 gcgtttgtct ggtatcgtcc gactgattcg gatcactttt gctattttaa tctggtttca
    17281 attacttttt gggacattct tttctattta tttttattac agaggctatt ttgatcgttg
    17341 gcgtgatgcc gttttttacg gtttttatca ggcgatatcg gctgtcacga actctgggtt
    17401 tgacgtcact ggggattcca tcaagccctt tgcacatgac tattttttct tgatcctgat
    17461 catgtttttg atttttgtcg gaggaattgg ttttcctgta ttgatggagt gccgggaatg
    17521 gctattatac aaacgttcca atgcgaagct tccgtttcgt ttttccttgt ttaccaaatt
    17581 agctgtgtta gcttttgtta tcttgtttgt ttcgggaact gtcttgattt atctattgga
    17641 aaaggaccat ttattccaag attccaatat gagtgtcaaa tggatcaatt cgatgtttta
    17701 ttcgattacg actcgtaatg ctggtctgca gattcacgat ttgggtgatt ttcaaatcac
    17761 aacactgatc attttttctt tactgatgtt tatcggatgc agtcctagtt ctgtaggcgg
    17821 cgggattcga acaactactg tagcaatcat cggtttgtat ctatattcct tcctcaaaag
    17881 tgaagataac atcaatattt ttggacggag aatcgatcaa gatgatgtgc gaaaatcagt
    17941 cgttgtcttt atgctttctc ttggtatgtg tttcttttgt atcgtttttt tatctgctac
    18001 agaagaacaa acgctgatct cgatcatcat cgaagtaact tctgcgtttg gaacaactgg
    18061 tttatcttta gggattaccg gagacttgtc tgttgtgggc aaaatcacga ttgctacact
    18121 gatgtttatt gggcggatcg gaatgctata tacattgatg ttattcgtgc caaaagaaac
    18181 acgagatcta ggctatgaat atccaagcga gaaaattatt atcggttaaa atgggaatat
    18241 aggtaagagg gaataataaa atcacagcag cttgaaacaa tcattttgtt tcaagctgtt
    18301 tttttgttaa atcatgcgat tttgtccgat ttcatgcact ttcagccgta accttttctt
    18361 aagaataaga aaagcaattt aacctttttt tcaacatatg gtatgattag ttgaatttat
    18421 tcgtcagcaa atcgtttttg gaggttacat aatgggaata cgcagtcatt ttgcgattgc
    18481 agttggaaaa acgtcgcaat gggcattaaa aacttttttt aaaggcggat caagtttacc
    18541 aggtaaacta gcgctgaaag tcgatccaca tatactagat agtttggcaa aagactacca
    18601 agtcgtcgtt gtcaccggaa caaacggtaa aacattgact accgctttaa cagtcaatat
    18661 tttgcgccag caattcgatg aagttctaac caaccctact ggtgcgaata tggtacaggg
    18721 aattgtatcg actttcttgc aggcaaaacc aaaaaaagga cagaaaaagt ttgctgtcct
    18781 agaaatagat gaagcaagtt tgagcaaagt cacagaatat atgaaaccag aactgttctt
    18841 atttacaaat attttccgtg atcaaatgga tcggtatgga gaaatctata cgacctataa
    18901 aatgattgta gacggtgccg caaagtcacc aaatgcaacg attatcagta acggtgattc
    18961 accaatcttc aattctatcg aaacagtcaa tcctagaaaa tattatggct ttgaccatga
    19021 agaagatcgt gaacaaatgg ctcattacaa tacagacggt gtcttatgtc caaattgtca
    19081 tcacatcttg cattataaaa tgatcactta tgcaaactta gggaaatatt actgtccaaa
    19141 ttgtgacttc aaacgtcctg aattggatta tcgattaact gatatggtac ggatggacaa
    19201 tgtgtcagca gatttcgtga tcgatggtca tgaatacgga atcgaagttg gcggtatgta
    19261 taatgtctac aatgctttag cagctactgc agtggcagag tacttcaatg tcgatcctga
    19321 taaaatcaaa caaggtttag gatatgacga gaaagtattc ggccgacaag aagtcatcaa
    19381 tatcaatggg aaaaaatgta cattagtact tgtcaaaaat cctgtaggta tcaatcaagt
    19441 aatcgatatg attggtctag ctccttatcc attttcttta gtggctttat taaatgccaa
    19501 ttacgcagac ggaatcgatg tcagctggat ttgggatggt aattttgaaa actttgccga
    19561 tatggatatc ccagctgtta tttctggagg agaccgtcat acagatatga ctttacgtct
    19621 aaaagttgcc gggattccag aaaataaatt gacagaaaca aaagaattac cagaagtaat
    19681 cgaaaaaatc aaagaattgc caactgagca tgtctatatt ttagctactt acactgctgt
    19741 attgcagctt cgtaaagaac tagctgctca aggatttatc aaaggaggaa tgaaccgtgg
    19801 ctaattatga actcaatatc gcccaccttt atggaaattt gatgaacaca tatggtgata
    19861 acggaaacct tttgatgttg aaatatatag cagaaaaaat gggggtttct tgccatacgg
    19921 agatcgttag tatacatgaa ccttttgatg ctgataaata tgacttggtt ttctttggcg
    19981 gtggtcaaga ctttgagcaa ttaatcattt caaaagacat ccagaaaaag aaagattctt
    20041 tgatcaacta tatcgaaaat gatggcgtca tgttagccat ttgtggtggc taccaattgc
    20101 taggtcacta ctacatggga gctaatggag aaaagatcca aggaatcagt gcactggatc
    20161 actacacgtt aagtcaggaa aataaccggt ttatcggtga tatcgttatc cataacgaag
    20221 aattcaatga aacttattat ggatttgaaa accacaatgg tcggactttc ttaggtgaag
    20281 gtgaacgacc tttggggaaa gtggtacaag gtcaaggaaa taatggtgaa gaccaatctg
    20341 aaggtgtcat ttaccgaaat gtcttcggtt cttatttcca tggacctatc cttgcaagaa
    20401 atgagaacct ggcagctcgt ttgatccgcc tagctttaga acaacgttac ggtaaagaat
    20461 tggatctgcc ctatcttgaa ggacaaacag cctagttatt cgaaaaaggg gaatgtgaca
    20521 aaaatttcgt cacattcccc tttttcgtat cctattttaa gcgacttgct tggcataacg
    20581 gttcacgttt tgcttgatat tcccgattgt tttcggatca ttgattcctg tgacttcttg
    20641 aatcaattgt tccaagtttt catggatctt catttcatgc aattgacggc tttgttcatc
    20701 ttcaggatca tagtaattaa aaataatccc cattgttgcc gtcaaatgtg ggcaagtcaa
    20761 gttatgttct tgtagttctc tcactggacg tgtaaatctt tcttgataac ctaacttacg
    20821 taatggtgtc cgagcgacac gtgtgatcgc atcagagata tttttgtttt ggaagcgatg
    20881 aatgattttt tcaatatacg catgatgctg ctctgcatca aacccccatt tggcaatcag
    20941 caaacttcct gtttcctgca aaactgattt taattgtgcc acaactaacg catcttgcat
    21001 tgcttcatca atggtctggt aacctaacaa ggcacctgta taagcgacag tcgcatgacc
    21061 agtattgaca ctaaatagtt tgcgttcgat atatggttct agatcatcta catataaaac
    21121 cccttttaat tggatttttt tattttttct ttggctatcg tcaatgaccc attctttgaa
    21181 aggttccact tggacgaata aaggatcttc atggtgttgt aatgggacga ttcgatcgac
    21241 tgctgcattt ggaaagccga tatatttgtc agtaaatgat gtttccggaa gatatttata
    21301 cacttctttt tctagaaatg ctgaaccgcc aatcatattt tcacaggcaa tgatatctaa
    21361 agatgttgtg cttccttcct tttctctttc ttggatacct tttgcaatca actcagcaat
    21421 aaaaggtaag atattcgggc caatggcggt agtaactaaa tctgcttcag cgatttcttg
    21481 gattactttt tctggatttg tttgattgtt gattcctttg acatttttta cagtgatttt
    21541 ttcttttgat tcatctgcta attcgatttc gtattctttt ctttcattta aagcatcaat
    21601 gatcgtgtga ttcacatcta cgaaagtaat ctcaaatcca ttagctgcca aaacctctcc
    21661 aataaatcct cgaccgatat ttcctgcacc aaaatgtact gctctcattt ttctctctcc
    21721 ttaagcaatt gctagatttt ccgttacttc ttctttgctg agcgcgtctg ctagctggac
    21781 aacattgtcc atatcactgc aataaagtgc gatttgctgt acaagttgca aatgctcatc
    21841 tccgactcct gcaataccga acaaaacagt cgcaatcttt tcttcttctt cggtaccaaa
    21901 atctacacca tctggtactt gaacgacaca gatgccggat tttttcacat atttttttgc
    21961 ttcatctgtt ccatgaggaa tcgcgataaa attccccata taaacagata acattttgtc
    22021 tctatctacc atggcatcga tatattcctc atcaacgcac cctgcttcta caagcatctg
    22081 accgcaatag cggatcgctt cttctttggt tttaaaagat cgattgagct cgatcatgtc
    22141 gaatggcaaa ctttgcatgc tgttttcctc ccttaagctg tctgtttcaa atattgtgca
    22201 atcgattcgt atttttgcgg attgaccatg ctgttgactg ataaatgaat ggattgaggt
    22261 gcagccatct gtactttttc cgctaaactt tctttggcta cgatcagtga atcaggttca
    22321 tcttttaaat cttggatatt gacttttctt aacgggatag ttaaatggtt cttgtctaat
    22381 atatctttga gcacggtcat ccccattgtt gctgatccgg aacgatcatc gtggacaagt
    22441 agaatctctt tgatttgttt gatgtttgct gaaagaaact cttctgctgg ctcattctca
    22501 atttcagaaa ctgatgtttt ctgcttgctg cttaattctt gaatgatttc atcatatcga
    22561 ggtgaattca aaaagttttc tactgagaca aaacgcgcgc tcggtgcttt ttgttttgct
    22621 ctttcttgta gttcgacctg agtaacgatc aatgtattcg agtcatctgt cagttggctg
    22681 attgcttgat tggtcaccgt ttgaggcaag tctgcttcct gtactttttt tctcaagatc
    22741 gaagcgccca tcgcacttga tcccattcct gcatcacaag caaaaatgat tttttgtacg
    22801 ccagagaatg tagctccttg aggaatacct tgggcacctt tggaagcttg cttagctgcc
    22861 tttgtctctt gaacagattt ttcgaagtct tcatttgtat ctttcgcatc cgctttcaaa
    22921 attactgcag aaataccaaa cgaaacagct gcggcaacaa tcacgcccaa aataacagga
    22981 aggtaagaat tgaacggtgt catcgctaga atcgcaatga tcgaccctgg agaagctggc
    23041 gctcttagtc cagcatccat caattggaaa atgaaacttc ctgacattcc tccgcctata
    23101 actgataaga ataataacgg tttcatcata acgtaaggaa aatagatttc atggatcccg
    23161 cctaaaaagt gaatgatcat ggctcctggt gctgaagatt ttgctgctcc tttgccaaac
    23221 aaagtaaaag caagtaatac gccaagtcct ggaccaggat ttgcttcaag caagaataga
    23281 atagattttc cagcctctgc tacttgttca gttcccaatg gtgtcaaaat cccatgattg
    23341 attgcattat tcaaaaataa gatttttgct ggttcaataa aaatacttgt caatggaatc
    23401 aaatgggcag ataaaatgat ctctacacct tttgccattg cttgagtcaa tgcatcgaca
    23461 actggaccaa tcgcagaaaa acctaataac gctaatccaa aaccgataag acctgctgaa
    23521 aaattattga ctagcatttc aaaaccggat ttgatccgtt tttggaatag ctgatcaaat
    23581 ttcttgatgg catatccacc aagaggtccc atgatcatcg cgcctagcat cattggaata
    23641 tctgttccga caatcacacc catcgttgca attgccccaa caactgatcc gcggtcacca
    23701 gcaattactt ttccgccagt ataaccgatc aataaaggaa tcagataagt tagcattggg
    23761 cttaccatgg tagcgaaagc ctcatttggt aaataaccat ctgggataaa tagagccgtt
    23821 aatacacccc aggcaatcag tgctccaata tttggcatga ccatgcttga taaagtactg
    23881 cctaattttt gtaccctcgc ttttagcgaa atgttgtttt tgggaatcgt ccgttccatt
    23941 ttgtctctcc ctctctcctt ttgatactct aattgtatcc gcttactaaa aagagaaata
    24001 gtcgtacttt ggcacgaaac tttgtgccaa aggtttgagt atgtcagcaa aataaaaaga
    24061 tttcggtatc agaaaacttc aattttaaat aaaactgtta ttttaatttt tttataatat
    24121 gcaaacaata acttttgtta gcatttaatt tagatgtttt ccattctatt atgttattaa
    24181 attttatatt ggaggcctat ctatgacatt actgatcaaa aacatgaaca tgaaacgtgg
    24241 taaaaaacgt gtgattcgac aattgaatct tttagtagaa tcaggagaag tagctgcttt
    24301 gattgccccg aacggatttg gcaaaacaac tttgctgaat ggcattgccc aactgctgcc
    24361 aacaacttat gatcaattgt cccttcacaa catctctcct actgcttata cagattatcg
    24421 ccggtctttc ttttttctag aatcaacgaa tcagttatcc gactatctat cggctgttga
    24481 ttatttgact ttgatcaaat actattggca gagcaaagta gaatgccaaa ctgttttcca
    24541 acgattgaag atgactgagt accttacttt gccgattgga aaaatgtctc taggaatgaa
    24601 acaacatgtc ttgcttgctg cttacttgat cagtgattca tctgtcatgt tattcgatga
    24661 accgttgaac ggattagacc caggaagtat tgatatcttg aatagcctca tcagacaatg
    24721 gcagaaagag gggaagacga ttcttctttc ttcccacgct atcgcgaata tccaatcgat
    24781 ttgttctaaa gcatgttttc taaaaaatgg agaaatcgtc acagaatcct caaatatgga
    24841 agagatttta gctatttatc gtaaattata tgaggtgtaa ctatgtcttt acttacattt
    24901 gaacgcaatc tcttactaaa aaacaaagta aactttttat ttcctctatt gttggtcgtg
    24961 ctctttgcat tcccactttt ttttgatcat aaacttgctt atacagaatt cgatgaactg
    25021 aatcataact atgaagagat gcaacgtttg attgaaacgt tgaaagaaga tgagaatgag
    25081 aaagaatttg tggaaagttt agagaaaagc aacaaactga tcgaagcaat cttacatgca
    25141 aaaaacacag ggaatgtcca gcaaatggtc gaagcaactt atcattatga aaaagatata
    25201 ctggatcgac tgatttctgg tcaaagacaa ggaattccaa tcattgaaca acaaaaacgt
    25261 gtcgagttgc tccgttatat gaaagaacat cagatccaaa gatattctat ttttgacttg
    25321 ccagcgcatc tctctttagc aaattactac gaaaatattt tttcaggaat gatttctagt
    25381 tttttgattt tatgtataac cgccttgttt ctttcttcca tcatctctta tgaaaaaaga
    25441 aagcaggtaa tctctctagt caatctatta ccggatagta tggtaaagaa acatagcatc
    25501 cgttttacca tttattatgg tgcagctatg ctaagtctcg tgatgccatt tttgatcgtc
    25561 tctatactag taataatcaa aaatggtttg ggagacttcc gttatcctgt aggaacgatc
    25621 attggtcagg agatacgaat cctgccgatg tatgagtatc ttttccagag ctttctgttc
    25681 ctgttgttgt gggtgctctt tttaagtaca atcagttttc ttctatctgc tttatttgaa
    25741 cattctctag tcaatctttt aggtacactt ctttgtcttt tcttagcaga gtatcgcttg
    25801 ttttcttcga ttggatggat agaatcaatc agtcattact tgccaacttc ttatgttgat
    25861 tttcaaaatg tgatcatagg aggagatatt ttctcgccac tagcttcaga acaggttact
    25921 ttcatgaatg gtatcttgac acttggtata tggagtatcg ttttattatt cataggtatg
    25981 ggcactatct atataaaaaa gagctattaa aacacaaaaa taataggggc ggtgacaaaa
    26041 accttgtcac cgtcccctat ttcaaataaa cggttttcta gaataaatag ttttcaaaag
    26101 cttgcatccg cagtaataag aacctcccaa caaaaatagc tcctcttatt tttatcttgg
    26161 ttgaagttat tacttgatgc aaggcagctt tttttactgt gaacattggt tatatatgtc
    26221 catgttcaaa aatcatttgg acttcttcaa tggtttccgc atcactgagc gccattactt
    26281 ggtcgatgtc tgaacagaaa aaggctaaat cttggagcac cgctaactga tgttcttttt
    26341 ttaaagccac tacaaataag agtgtcgcga tttttggttc ctcttttgtt ccaaagtcca
    26401 caccatcagg cacttggact aaatagattc cttcttctac tacttcttca tctttgtcag
    26461 tcccatgtgg caaggctacg aaattcccga tatagacact cgctttttct tgtctttcga
    26521 tcattgattg gatatatgcc ggtttgattc ccccttgttg ggtcatccac tggccgatct
    26581 cggtcaacgc ttctttccaa ttttgatagg attgatcgag caatattttt tctgctggta
    26641 gctgtatcat cttttcacct tcatttcttt atttcttcaa tcaggatttt cgctaacaac
    26701 tgataaacga tttctttatt tcctgagcgg aagatctcgg tgttcaagtc attcatgatg
    26761 attgctccac tgatctttcc taaaagaatc ccgtcttttt cttggattgg cgaaggcgcc
    26821 agcataacta acatacggga caaatcgact ggctgtctat ccatcccttc aatggtcaac
    26881 ggatgtttca aattgaaaat acaaaagatc ggtttagaaa tcaatgagct ggatgtatgg
    26941 aataacccca tatttgtatg aggaataccg ataggtgctt gttcatatcg cttaagcagc
    27001 cggcgatgaa ccacctcttc atccgttact agtccttcag gaaaataagg aaataagctg
    27061 cgaatcgttt cggaaatcgt ctcaggatta tccagttctt ggataaaaaa acgaccgagt
    27121 aattgattga tttgatccat gaaatgcatt gtttcctcat aagtatcttc tatcatccac
    27181 tcgttattgc tgttatacgt aattttttgc ctttttttct tctcaatatg cgaaaaagct
    27241 tcttttagct gcttgacttc atcttctagc agtagcgggg agactaaaat atattttcca
    27301 ccgtatcctg gtaaaataga tgtagaaata acaacatcat attcttcttg taaatcgatt
    27361 ttttttaaat cagcaatccg atagaaatga atttgttgga tgaagggaaa ataccttttc
    27421 aatcgtagtt ccaacatgct agtagaagct aatccacttg gcgaaaatcc tgcaatactg
    27481 atattgcttt ctttcggact tcgttccaat gaattcgcaa aatgaaggac catataagcg
    27541 atctcttctt cggataattt tttttcttga aaaatccgct ctactgcttt acggattgca
    27601 ttcgcaactt cctcgtattg aaccatgatt ttttctaaaa tcggattggt cagtgtctct
    27661 tcttgtaaaa cggctcttga aaacacacca gataaatgag tcaacagcat tttgtacaaa
    27721 gtttcatctt cataaaaatg gacattcgtc tcttcactta cttcttgaat cagttgtttt
    27781 actaaataag caagctgtgt atcgaacgtc tcttcaaaga aattctgatc aaatgagttc
    27841 gtgaagtcat ttaataatcc tgcaaaaaag acgatctcat ttactggata aagttgtttt
    27901 gtctcagaag cgatccgtga aaacaatcgt ttagctgtct gtagtaattc tttgtttgcc
    27961 agactattat atgtctcatt tgtcagtaaa tgatttttcg tcacacgctc catcgtcaat
    28021 gtcagcatca aaaccaaatg ttcaagcttt ctatcactta gattggtctt tttttggatc
    28081 aattcttccc cgattacttt gcgtgcaaga gatagatgtt gcggatcaac gaatcgaaaa
    28141 aaataattca gtgatgcatc gaaagaaata ctatgaaaaa gttcatattc attgatttct
    28201 aattctaata cattcgctgt cagaagccgg cggtattttt ccggtccttc gatctcgtat
    28261 ccctggttcc gaatgatttc caaaggcagt tggcgaatac tttcttccaa ctgtttgata
    28321 tctgcataaa aagtggtatt actgatgcga tatgattcca tgaaatgagc aagactcaac
    28381 ggctctgtcg tcagtaacaa ctcggctaaa atcgcgtgtt gtcgtttagc agtggataag
    28441 tcattacttt tcccatctgt attttctttt aattgctcta atacttcttc tgatgcctca
    28501 atgacaaatg agcctctagc tgcttttttc aaagaagcat ttaccgattt caatgagact
    28561 tcaagattat ctaattcgcg gtaaatagtc cgtttactga ccttcaataa attcatcatt
    28621 ttttggatag atacaggtga cgggctactg agaaattctg ctaataattg tttttctctg
    28681 ggcgataaat acatcttata tttctccctt cacgagtttt tcgtattcat tcgtagctac
    28741 ccaatgttca actagaacta gccgagggat cttttcttct agctgttcag ttacagctag
    28801 ttctctttgt gcgatataaa tcgtttcttc ttggattttg attttttcta ttgattcttt
    28861 tgagataaca aactgttttt tcgctttttt tgctaattga cttaaaatcg tcatgcccat
    28921 agtttgtgag ccgcgtctgt tgtttttata caaaaataca atattagcag gcgacgtttt
    28981 ttgttctgtg atatctgcta tctctttttt ttcttcccgc tttggaaatt ggatcgcttc
    29041 ttttattcgt gacagcaaga tatctgtttc caaaaagtga tccagtacat agatttgact
    29101 ttgaggtact ttttctcttg caagacccgc tagttcatgt tgcacgataa ccagctgatt
    29161 tacttggtta ttcaattcat agatagagct gtatccgaca gaaagatcga ttttttctgc
    29221 tgctaatttc tttttcagca gggcggctcc catagcactt gatcccatac ctgagtcgca
    29281 agcaaaaatg acggaatgaa tgatagatgg ttccaagatt tctccccttt ctttgaccgt
    29341 tttgttctct ttttctttat ttggtaattt caatagtatc gctgcacaaa tgaaggtcac
    29401 aaatgtactg attgctatcc ctatacttac cccagctagt tgtggataag gcgcattggc
    29461 aaaaatcacg agtagtgacc caggcgatac aggtgcagct aatcccgtat ctaaccattg
    29521 aaatatcaac gtgccgcttg ccccaccagc cattacagct aaaaatagat acggtcgcag
    29581 caagacaaat ggaaaataga tttcgtgaat cccgccaatc gcatggatca tcaatgctcc
    29641 actcgcattt actttttcct gtttttctgc aaaacaaagg atagaaagta agatccctaa
    29701 accaggtcca ggatttgcct ccatcaaaaa taaggaagag tacccgactg tttgtgagaa
    29761 ttcgattcct aaaggtgtca atacaccatg attgattgca ttattgaaaa atagtacttt
    29821 tagaggttct aagatcagac tgacaagtgg taacagattc attgtgacta gccaagacac
    29881 aacggaggcg agcaacaagt gaacactatt taaaactggt tcaataaaaa cgattccaat
    29941 tatacaaata acgctaccag tcagtcctac tagtaggttg ctgacaagca tttcatatcc
    30001 agccttgaat ttcacatgga atctagaaac aaattgttca tatacgatgc cggcaagcgg
    30061 cccgataatc atcgctccta cgatttgtgg agcattggaa cgagcgatca accctaaaga
    30121 agcaattgca ccggcgactg cccctttttg tccccctacc gatttcccgc ctgaataact
    30181 gatcaagatg ggtaaaagca gctggatcat ccaatggcat acctcttcta atgtggtgtg
    30241 caaatcgcca gacacacctt ttgttgctaa tgacaagatt ccccaagcga taaacagact
    30301 tagatttggc atgatcattt catttaagtg atgtccagct tttctcagtt gtttcataga
    30361 cacgcgactg ctgttgtttg ctttccattt gtattccatc tttttcacca gacttctatt
    30421 tattgatgga cggattttat gtagaaaaag cagcaaacga aaaaccgtct gctgctttca
    30481 gctatctggg aactatttgc ctggttcaga cgcaatgatt gctagttcac cttggaccgc
    30541 ccactcagaa acgccatttg gaataataca gcttgttcct ttttctaatg gatatgtttt
    30601 tccgtcaacg acaaggtctc ctgctccttc gattaccgtc atcaatgtat aaggggcttg
    30661 ttttttgaaa gatgtgattc ctttaatatc ccactcatat acattgaaaa actcagtttc
    30721 taaataagtg acgatcgatg aattcccttt tcggacttct ttgatttgta attctggtgt
    30781 tttcgcaggg acagttgtta catcgatcga ttgttggata tgcagctctc ttgtttgtcc
    30841 ttgcgcatct tttctgtcgt agtcatacac gcggtaagtc gtgtcagaac tttgctgtgt
    30901 ttctaaaatc atgattcctt taccaatagc atggatcgtt ccgcttggta cataaaagaa
    30961 atcacctttt ttaactggta ctttcttcaa aaggtcatcc cagcgcccat ctttgatcat
    31021 ctcagctagt tcttctcttg tctttgcatg atgaccatag atgatttctg caccaggttc
    31081 agcatcgatg atataccagc attcagtttt tcctaattca ccttcatgtt tcatcccata
    31141 ggcatcatct ggatgtactt gtacagatag atcatcttct gcgtctaaga tcttgatcaa
    31201 taatggaaac actggttctg aaggatggcc aaacaattcc ttgtgttctg accatagttc
    31261 atctaatctt ttccctttga attcgccatt ttctactaca ctgacaccat gaggatgcgc
    31321 actgatcgcc caatcttctc cgattttatc gttagggata tcaaaaccaa agactgaacg
    31381 taaacgactt cctccccaaa ttttttcttg aaaaactggt tttaaaaaca taggttcctg
    31441 cataattcaa actcctctca tttttcatag ctattatagc attatttcgg taataccgct
    31501 ttctctttca aaaagttttc aacaatttca tctcgacata tgagatactc cgcacgatga
    31561 tcgacaggat gtacgcgatt tgacaaaaat atcaacgctt cttgtgtttt tatatcaatc
    31621 aagaaaaacg tacctgtata accagtatga aaaagaatcg catgaccgtc ttctacatcc
    31681 ttttttaagt cccatcctaa agaacgatag ccattttttt tcggtgtttg atcttgcagt
    31741 aaagaatcaa tcgtctcttc ttctaaaaaa cgaccattac ggatttttcc cttgttcaaa
    31801 tacatttgga caaaagtaat gctgtctttc aaatcaataa agagacccgc gttacctgca
    31861 tgttcagcca aaactcttgc tttcggatca tgagtttgtc cacgcaaaac ctcacccgaa
    31921 ggcagttgtt ctgtgggaac gatttttttg gaaggaaaag gaagaaataa gctgttcatc
    31981 attcctaatg gttccaatac ttgttcttga aagatttcca ctgcagtttc ttggtaaatt
    32041 tcctctagca tcaacccaag aagaatcgta ccggcatctg tatattttac ttcttttcct
    32101 agttgctcac ctggttctag cttcaaataa gcggcgatca attcttcctg agatagctta
    32161 tctctgtttg gtatccatgt tttgatatca gaagtatgtg tcagtaaatg acgcaaagtg
    32221 attgtctgat tttcaaattc aggaagatat ttatgaagcg gttgatcgag ttctatcttt
    32281 ccatcttcta atagacgtaa aactaatgaa gtggttgcaa cgactttcgt cagtgaggct
    32341 gcatcaaaca acagatcttc tgtcatcagc tgcttttcag gaacgacttg ggcaaagccg
    32401 gctgtaaatg tttctacttg attttctttt atgaaggcga ctgctacacc tggataaaat
    32461 ccttcttcca tctttttcaa aataagctgt ttcgtgtgtg gatacatctt tttctcctgc
    32521 ttttctatca gattcttaca gtccaagctt aaagcttaat ctatgaggaa tcaacctttt
    32581 ttacacaaaa aaactgcgcg aaaaaccgcg cagtttcccc cggtatacta ttttctcttt
    32641 ctatctctag aataagcgat agtatgaccg ttcataaaat gacgagacat gcgacaatcg
    32701 ttaagaaaga aaaagttaag cgtcgcatcg aatgtcagtt ttattctttt cttttggctc
    32761 actgacgaac caccattcga ttcctatagc atcatagatt gtgagtactg tgtgcttttt
    32821 gtctaagaag aaatcaactg atagttgctg caagtgagca atcagtcctt ccatgctttc
    32881 agtatcgatc atgaatttca gaaaatcaag tccaatcact tcatctgtag gcaaatcaat
    32941 tgcgcctccg ctagcttctg tcaaaccaac atggaaatct ccttcattca atacatggat
    33001 gccctcttct tcattatgta ccttcaaacc aagtacatga ttaagaaatt ggcgttcttt
    33061 tgttaagtta gtaacattta aatggatttt ttcaaaataa gaacctgttg atagtttact
    33121 gaatttttct tcagattttc ttaataatgc ttcttgatcc attgtttctg gaatttctct
    33181 ttggtcgttc ttattctctt catggtaaat ttccaattca ttctcttctg ggtctacgag
    33241 caaaatcccc atacgtccat gatcttctaa agcttctttg attggataat tcattttacg
    33301 gatacgacaa aggatatctg ccatttcttc tgtgctaggg ataatcaatg aaaaacggtt
    33361 cagctttttg atcaccccca tgtgatcatt cgctctagga ctttcttcca gcagcaacat
    33421 ttcacttcca gcttcttctg ttcctaaaat ggctaattcg ttttcttctc ttttcaaatc
    33481 aaagccaaca acgttcttgt aaaaatcaat cattttatct cggtctttca cccgaatggc
    33541 tacacttttt aaataggtgg cagcccccaa ttgaaaatct ttcatatttc ttgctcccct
    33601 ctacgtcaag ctttatttta acgatggatt cttcttcttt caagcaataa ctttgatttt
    33661 gttaaaaaaa atgtgagaaa attcgcattt tgcttgtttt ttgtaaatta atgagtaaaa
    33721 actcttataa aaagaggttg tgaaaaagct gttctgcatc aagtaataag aacagccaaa
    33781 caaaaatagc tcctcctatt tttcgtttgg ttgggcttat taccgcagat gcaagctttt
    33841 gaacaccgtt taaggaagag gttgtgaaaa agtcgcttag tttcgagtag taagaaaaat
    33901 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
    33961 tttgaacacc gtttaccaag aggttgtgag cctgccgttt aactccgagt cacaaggagc
    34021 aatttcaaaa aacagcttct caggtttgtt gactattgtg acttgtgacc gaggagttgg
    34081 caggagaaca ccgtttaagg aagaggttgt aaaatcagcg gtttgacctg agtattagag
    34141 atacaaaacg gaaaaatagc ttctcatatt ttgccgtttt ttgagctaat accgaaggac
    34201 agctgattga acaccgttta ttcggaaaaa gggactgtga cacgactttt gtcacagccc
    34261 ctaaaaaaaa taataaattt gtactattct atgaagcttc ttcttcagaa aactgactgt
    34321 tataaagatc tgcatagaat ccgtcttttt ccatcaatgt atcgtggttt cctgtttcta
    34381 cgatcgaacc atgattcatc acaataatgt tgtctgcatc gcgtattgta gacaagcggt
    34441 gagcaacaac gaaacttgtc cggttttcca ataggcggtt catcgctttt tgaatcagta
    34501 tttctgttcg tgtatctaca ctagatgttg cttcatcaag gatcaggaca tctggatttg
    34561 ctaagaatgc ccgcgcaatt gtgattagct gacgctgccc ttgcgaaata ttgcttgcat
    34621 cctcgtttaa tacagtgtta tatccttctg gcaatttacg aacaaaatcg tctacgtgag
    34681 cagctttagc agcctcaatg atttgttcgt ctgttgcatc gtcgttccca tatttgatat
    34741 tgtcatagat acttcctgta aacagccaag tatcttgcag taccattgaa aactgtgcgc
    34801 gcaattcatc acgtgaaaga tcacgggtat ctacaccatc gtaacgaata ctacctccag
    34861 aaacatcgta gaaccgttca agaaggttga tcagtgtcgt cttccctgca ccagtcggac
    34921 ctacaatagc gaccatctca ccaggtttga catccaagtt aaaatcagtc attagcaagt
    34981 tatctggtgt gtagccgaat tgaacatttt caaaacgaac tttgtatggt gtatcttttt
    35041 cttctggaag gccagatttt tcattggaca tctcttcttc atccaacact tcaaataccc
    35101 gttcggctga agcaactgtt gattggatag tgttcatcaa acttgcaagt tgagtgattg
    35161 gttgagagaa ctgtgttgta tattgcaaga acgcttgaac atcccctaat gtcatgttcc
    35221 catttgcaac ttttactccg cctagtacag cgacgaacac atagcctaga tttttaacga
    35281 aattcatcaa cggcatgatg attgccgaaa taaattgagc tttccaacca gcggcataca
    35341 gattctgatt ttctttttca aatacttcct ggtctttttc agtatgattg aatgttttaa
    35401 caatggtatg accaccatat gtttcttcta cttggttatt caataaacct aaactttttt
    35461 gctgatctgc gaaaaacact tgtgatttcg gcgctacgat catcacgatg atcaagctta
    35521 aagggatcat caataacgcg actaacgtca attgccagct gattgaaagc atcatcacga
    35581 tgaccccaat caatgtgact gcactagtta caaattgagt caaattttgc tgcagcgtgc
    35641 ttgcgatgtt atccatatca ttgattgctc gagacatgat atccccattt gtatgtgtat
    35701 cataatagga aatcggtaca cgattcattt tggcttccaa atcatgacgt aattcataaa
    35761 ctgttcgttg ggaaacacgt gtcataataa attgctgtaa aaagttgaat acagcagaaa
    35821 tcaaatacat cacgattact gtcgcaatga tctgcgcgat tttatcaaag tctatcggaa
    35881 attttgttac ttgttggcct tgttgcatct gttgagcgcc agccattaca cctttgaata
    35941 tttctgtggt tgctttcccc aagacctttg gtgtttggat ttggaagatc acggctgcta
    36001 ttgctagtac aaatacagcg atgatcgcaa ccatacgttt agacatatag ccaaacaatc
    36061 ggcgtaccgt tccccagaaa tttttaggct tttcaccttt tacaccgaga tttctgccag
    36121 gtccaccatg tcctggaccg cctgctggtc catgagaggg acgtgtgttt gttttactca
    36181 tgctaagtcc tcctctctta gttgtgaatg aacgatttct tgataagttt cgtttgttgc
    36241 taatagttct tcatgtgttc ctttgccaac cagttttcct tcatctagca caaggatcat
    36301 atctgcatcc attactgtac ttactcgttg agcaactaaa acggtgatac tttctttcat
    36361 attcgttttc aatgcttggc gaagattggc atccgttttg aaatccaacg ctgagaagga
    36421 atcatcaaac acatagatat ctgctgtttt gactaatgcc cgtgcaattg ccagacgctg
    36481 tctttgtcca ccagagaagt ttcctcctcc ttgttccaca tggctatcta agccatcttc
    36541 catctctgaa acaaaatctt tagcttgtgc gatttctaat gctttccaaa tcatttcatc
    36601 tgttgcatcc ggcttaccat actgcatatt gtctcggatc gttccagaga acagaactgc
    36661 tttttgagga acaaagccca ttaattctcg caaattatat tgagtcatgt cactaatgtc
    36721 cgttccattt atttggatcg aaccagattc gatgtcatat aatcgaggga tcaaattgac
    36781 taaggtcgtt ttacctgaac cagtcccccc tatgattgcg acgatctcgc ccgacttggc
    36841 ttggaaatca atatcttcca atgcaagttt ttctgctcca tgatatcgat aattgacatg
    36901 attgaaggcc aatgttgcgt tttttccagc aaaagaaact gttttaggat tttcagggtc
    36961 atggataccg attttttcat ccaacacttc attaatacgg tcagctgaag cttgtgcacg
    37021 aggcaccatg ataaaaatag cggaaagcat cataaagctg atcaagatct gcatcgcata
    37081 agtcataaat gcaatcagat taccgacttc caaagtcata tctgctatgt agtgtccacc
    37141 aaaccaagtg attgctacgt ttgtaccgct catgatcaat gtcatcattg gcatcatcaa
    37201 tgcgacgatc gtattaactt tgattgccgt atttgtataa tctttattcg ctaaatcaaa
    37261 acgattttct tcaaagcgtg tcttatcgaa tgctcgaatc actctgaccc ctgtcaatcc
    37321 ttctcgaaat accaggttta aacggtcagt tttcttttgc atacttttga ataatggaac
    37381 agcaaagtac atgattccgc cgatcaaaat aatcattact gggatgacaa ctaagaagat
    37441 ttttgtcaac tgatgatctt tttgataagc aagtatgctc gcgccaatca acgtgattgg
    37501 tgcattgatc atcatacgta aaaacatttg tgtaaccatt tggatttgag tcacatcatt
    37561 ggtcgttctt gtgatcaaag aggccgttcc atatttatca aacgcatctt ttgtcagact
    37621 ctctgatttt ttatagacat ccgtacgcaa ttgcttaccc agtttctgtg attcacgagt
    37681 agcaaaaaat gtatttgcga tagcagctaa gatactgatc aaagaaaagc cgatcatcac
    37741 aaaacctgta tgccaaatat aatcgacatc tccttgcgct acccctttat caataatatt
    37801 ggaggtaagt gtcggcaaat ataaatctgc cagtacttgg atcaccatga aaactgcagc
    37861 tgcaattgct gaagtcaagg agatccgttt tacgattttt agcatctagt tcccttcttt
    37921 ctatttatat actccgtttt tcagccaaga aagtttcaaa ttgaattcac tgattgcttg
    37981 ctctactgag taatcttcag atgttgaaaa taagcgatac gaatgcgcaa ttgttgtaaa
    38041 tacagtattc atcactaatt ggatcagtaa ttccaattca tgatcatttt ttactttcag
    38101 cttcgtccga tcgatcaatt caagcaactc ttttgcatct tgtttgtgtt ctttatgtgg
    38161 atcgtgaggc gttttttggc gactcgtatg aggagcgact tttcttgagg cacggtaatc
    38221 catgttcata aacaagttac gataaaaaga agcattctcg ccttccaaaa tctcataaat
    38281 cattttagaa aaataggatt cgaatccttt gaatagatca ccatcggatt ctttcattag
    38341 ttgtaacata tctttagagc tgtcacgtct cattgtctca aagtaataaa aataaagatc
    38401 ctctttatct tcaaaatact gatagaaact gcctctaggg atatccgcta atttgacgat
    38461 attagcaatc gaagcttctt ttaagggtac tctagaaaac tcgattctcg cagcctcgat
    38521 tagtcttttt tgtttttctt taggcaaatg gaaaaatgtc tgtgtcggca tatggattct
    38581 cctttctttc aagatgacac attgtcatat gacgctatgt cattataaca cctcctacct
    38641 gttttgcaag acatttgcat agtttttttc attatcatcc gatacattaa aaaagtgata
    38701 agaggaatcc ttccatttga attaatgaga gttgcccatt aaaatagcca catactaaac
    38761 aaaggatgag ataaatggcc caatcaatta gtgtccaaga cttcaataaa ttgcctctcg
    38821 atgctgacag catcgtttta gatacaagaa ataccttaga ttacacaaaa aaccacttaa
    38881 gccactcgct ttctatcccc gctgctatct tgccaagaca attaaaaaat ctagatccaa
    38941 agaaacttta ttatattcta agctatacag gcaggcgatc agaagcatta gccgatcaac
    39001 ttactgctaa tggttttcgt gctgtttata tcattggtgg gatggaagct cttcagtcga
    39061 gtgttgcttg aatattgctt gttagattca aaagaggctg tgacaaaaaa tcgtgtcaca
    39121 gcctctttta taccctgtct ttttttagtt atttattctt caaccttatc aatatgactt
    39181 gatagccttt tctttttcga gtaaactgat tttgttagtc atagttataa caatcatagc
    39241 aataaaagga gaaggtaagc atatggcatc tgttttagta gtcaaaggtc atcccctaac
    39301 tgcagaagaa tcgcgcacag ttaaggcatt gacgtctttt ttaacaagtt ataaagaaaa
    39361 tcatccagat gatgaagtga ctgttttgga actttatcgc gatgatattc cggaaatcga
    39421 tgaagaatta ttatcaggtt gggaagcatt acgtgctggt gcagaattca cttccttatc
    39481 agaaagtcaa caacaaaaaa ttgctcgttt caatgaattg actgatcagt tccttgctgc
    39541 tgataaaatc gttatcgcaa acgccttatg gaatctaaat atcccaacaa aattaaaagc
    39601 ttggttcgat accgtcaatg tagctggaaa aacgttccgc tatacagaaa acgggccaga
    39661 aggattagtg acaggtaaaa aagcactgca catccaatct aatggcggtg tatacaacgg
    39721 acaagacttt gcctctcaat atgtaaaagg tattttaaac tttgtaggca tcgatcaagt
    39781 agatcagcta ttcatcgaag gaatcgatta tgaccctgac cgtgcagatg agttgatgca
    39841 aaatgcatta gataaagctg ctgctttagg taaatcattt taaaaattga gataaatgca
    39901 tacaaaagag acagaggaaa aaatcttcaa agcagcattt gtgccttgga tattttccca
    39961 tctgtctctt tttgttattc tttctgcttt ttcaacggat tttcttcata aagagaagag
    40021 attgttgtgt accattcaaa aacatgagta atcactactt tagctgctgc ataaacagga
    40081 atccccaaga tcacaccgat gattccgaac aatttcccag aagtcagcag aactaataaa
    40141 atcgttactg gatggattgc taactgattc cctagtacta atggagagat caagcgtcct
    40201 tctattgtct gctctactgc aaaaacgatc agtactttga tgatcatgaa tggacctgct
    40261 acaatggcta aaaagatagc cggaatcatc gctaaaaatg atcctaagta agggatcagg
    40321 tttaaaaaac ccgcaataat ccccaacgtg acagcatact ctaaaccaat gaccgcaaaa
    40381 ccaatcataa acatgattgc cacagcaaaa gccacagtta gttgtcctct tatataagaa
    40441 gaaacttgac tattcatttc actcagcaca ttcaacgtcg gtttttgcat gcgtgtcggt
    40501 aaaaatttga caaaataagg tgctaattgt ttaccgtctt tcaatagata aaataagata
    40561 aacggcatcg tcagcagagc cactaaaata gtcgctaccg cgccgacaaa acttccaaga
    40621 ctctgaactg tactcttaga tatatcttgg atcatatcgc ctgccgaatt catgaactta
    40681 tcacctgctg tttccaactg ttcgcgaaat tggttgaaca gcgggtcccg caaaatctcg
    40741 gttaatttat tatcaatcgt atctacatat tgagggaagt tactgatgaa gctcactgtt
    40801 tgttcctgaa tcttagggat gatcactacg ctcccccatg cgattagtgc aacaaccaaa
    40861 acaaacagcc caatgatact gtaaagcctt ggtacttttc gcttttcaaa gtaatcaact
    40921 accggattca tcaagtaata caagattcct gctaaaatga taggcagacc tacgattgct
    40981 aaaaattgcc agattggtgc aaacaaatat gaaacttttg taaataaaaa gacgatcagc
    41041 aatattaaca atacaacaag taaggctgtg actacttgat tatttaaaaa ccagcgccaa
    41101 aaccacgata ccggtctgtt cttcttattt tttccttcca taattcctcc tgttagttat
    41161 aaaaaatttg gcttcccaaa ccaatagcag gcagtctatg cggatgaaga tagattccat
    41221 ttgcaatttg tccttcttct ggacaagcat caaaaatcaa tgatacgtga gctactgtct
    41281 ttaaattccc attggccatc ggaccgacat aatcgatcgt atatacctga tcatcaaaag
    41341 caattgttcc gcctgctttc aaagaaaaag gttcgtcttt tgatacttct tgaatcaccg
    41401 aatattttcg taaggcagct gttgctgttt tatcgaacaa aatcagcatg ggttcttcct
    41461 tgtttattgc ttctgtccca atttctgtaa tctttgcctg aatcattgca ctctctcctt
    41521 taattgcttt caaaaacagt ataacacatt ctcattcttt agccgtgtgg aataattatg
    41581 tgatagaata aaaacgaaaa ctatttcatt acaattagga ggaatcagct catatgatcg
    41641 aaaagataat tttaggaacc tatacgcgtc gcgaaagtaa aggaatctat acgatcgacc
    41701 ttgatacaga aaaagaagaa ttagccaacc tttcattagc tgttgaagaa aatagcccta
    41761 cctatgtagc aaaaagtaaa gctggcaatc tttacacagt tactagtgtg gatggattag
    41821 gtggtgccgg tgcgtacgat aaggattttc attttttgaa tgcggtaaca gagtctggcg
    41881 ctcctttgtg ttatgtagcg gttgatgaag cacgtcaatt actatacggg gcgaactatc
    41941 ataaaggtga agtaaatgtc taccatatat taggagatgg cgaactgaaa gcagcagatt
    42001 caatattcca tcaagaagcg acaggtcctc ataaaaacca agatcatgcg catgtccact
    42061 atacggatct gactcctgac caacgattag tcgtatgtga tcttggtaca gatcgtgtgt
    42121 atacttatga tgtgtccgaa aacggcaaat tgaatcttgt aactaccttc actgcagagc
    42181 caggaacagg ccctcgccat cttgtctttc atccaaatgg acaattcgct tatttatttg
    42241 gtgaattaga cagcacagtc cgcgtgcttt cttataataa agaaacaggt gcttttgaag
    42301 aattacagaa aatatcgacc ttgccagaag aattcgacgg tgaaaatgga ggggcagcta
    42361 tccgcatttc aaatgatggc aagttccttt atgcttctaa ccgaggacat aactcgattg
    42421 ctgtattcgc agtttttgaa gatggttccc acattcaaaa caagcaaatc atctcaacag
    42481 aaggggattt tccccgcgat ttcgcactag atccaagcaa taattttgtc gtgtgtgcca
    42541 atcagaacac cgataatctg acattatatc gccgtcatcc tgaaacagga ttactggaat
    42601 tactgaaaaa agatgtctat gtaccagaat gtgtctgtgt ttattttgat cgttagtaag
    42661 aaaaggagaa tgaaatgaat cagcaagacg tattagacag actacgggaa gaactaaata
    42721 ttcctttctt tgatgggaaa atcgaagata aagagtatag cgaagaggaa tatcagaaac
    42781 tcaaagccga tttacagaac tactttgaac aatatgtaca gaatgtagaa aactaatcag
    42841 ctttccatac tatctgaaaa gaacatcagg acaagacttt tccgtctatc ctgatgttct
    42901 tttctacaaa taaaaaaccg ccgagatggt tagactcgac ggaaaaggag tatttactcg
    42961 attttgagta agtacaaggt tgttgttggt tataggtatg tcattatcat aaaggatttt
    43021 gatcactcta tcataaaggt aatattacat ttatattaga taactctagt ttttattgtt
    43081 atcaaagatt tcttttattt tttcaacaac aaattagtca ttttttggat ggcagctgtc
    43141 aattggtctg tcgcttggtc ttgttttgct tcagatgtat tgaatagatc ttcatctacc
    43201 cctgattcaa gatcgatact ttggatcatt tcttcacagc ctgctacata tgaaagataa
    43261 gctttttcaa aatttttatg aatgcccatt gcttttgctg gtggacgcaa agtactgact
    43321 ttcataagca ttgcccgata tttttttgtt ccttcttcaa ataacaggat gatctcttca
    43381 agagtcgatt tgtccagttc acttgttttt ccttcatcaa ttgcgtttct gatcacttca
    43441 tatttcggat gcattccttc tccgattgct tctgtttcct tgacgatttg atcgatggac
    43501 tgcacataat agccaatatt cggtaacatg ttcgttttcc tactttctcc attgttgtta
    43561 ttatttattc tacttgtttt tatcctcaaa tgacaagtac ttgaaaaaat ttaatggttt
    43621 ctatacagct cgccattctt attcgtgctc aaagaaacca tctgctaaac tatattgttt
    43681 ccctgcgaca atgtcatatt ggatcaattg atattcgtcg taaatctctt gttgcgagcg
    43741 attgaattgc gcttctttat accactgtcc gttttgatag tacagttctc gttcaaacgc
    43801 cggaagttcc tgttctaatg ataaaagcag ctgataaaag ccatttgttg tctgattcgt
    43861 ctgttccatt agattcgctg caaaataaaa cggactggtg attgcatcgt gagtcgtttg
    43921 cttttctaat tctcctttac tgtcgaacat aagaaattgt gtttcatgca atgtttgttt
    43981 gtcatttttt gcttggatcg tatctgaata gatccctgga agatgatccc cccaaaaaac
    44041 aactaaagtc cttctagaaa gattcttcaa ttcttccgtg aactgcttca gtgccgtgct
    44101 gctataggaa atatcttgca gataattctc taagtcaagt gtcccacttc catctgaagt
    44161 ttttgcagga tagtctagat tatcatactt tccatcgtag ggcatatgtg tctgcatcgt
    44221 gactaaatga atgaactgag gtgttttttc ttccttgaga agtgtcatta cttctttgta
    44281 agctgactca tcagaaatat atggattatt ctctatcgta tccgtatagg tcatcgtacg
    44341 ctcgctgatg aactggtcaa atcctaatgt ctgataaaca tcctctcttt tatacatcga
    44401 agtattgtat ggatggatcg ctgtcgtctg gtatgattgt gcgtttaacg ctgaaacgat
    44461 agaaggaagc tgatccattt ttggtacaag catcgtgtaa ggggtggtga gttgcgcatt
    44521 aaataacgcc atagaaaaac cagtcaatgc ttcaaattcg atatttgctg ttccaccgcc
    44581 atagttttga gaaagcatat tgccactata tgtttgatca gctacttcat aataatctgc
    44641 caatggctca ccagatactt ctacgccgtt taatcgacta ggatctgaga aactttcact
    44701 catcacgaac acgatgttcg gcgactcttc ctctacagtt ttattttttt catcggctag
    44761 cttctggtat ttttcagtga tttctttgat cttttctttc gaatatcctt caggttcatc
    44821 cattggttct accttcagat tgtacaaaaa cccaccgata aaaccagtgt tatagtagtt
    44881 cattttctgg ctgtaaggta tccatagtgc cgttttatta tatgcttttc gcaacaaatt
    44941 atcgggattg ttgaaattac tgatataccc tagcagtcca attgccacaa gcagtgtcgt
    45001 taatcggatc aattggaatc gccttccttt tttcaggctt cgaaacatgt accagcaaaa
    45061 caatcctatc acggttcctg cggcagctaa gatcactgta aacagcatag tgccggtcat
    45121 atctttcagc aatccgattt cagtgatcat cttcaaatcg tctggataaa tcggttcttg
    45181 ccgataactc attttcatat aatttgcaaa acctaataca ccgatggcta cgacatacgt
    45241 aagggaacct aaagggacag atcctgctag tgcaatcaga aaaataagaa taatcagcaa
    45301 gacgagacag gctaagaaga atttttccgt atgccaagaa aaagcaaatt tcaacgcaag
    45361 gtctacggat agatcatttt gacaccactg caaaaataaa ttactaaaaa caacaagaaa
    45421 aaagatactg atgattgctg ctgttccttt taaaatcttt ttctgtttgg tcgaaagtct
    45481 gcttatatat cttttcaaat gcttgctcct tcatttctat caataaaaga atgttgcttc
    45541 tcttatttta gttgtacgaa attcgaaagt aaagaacgga aagaagaatt aatgaaatcc
    45601 aaatattctc tttctttatg gcctttctgg tttctttaat aagcggacct ttcgtactcc
    45661 agaaattttt tctagctgtt gtttcacttg attgagctgt tcaaaatcag tactgtctat
    45721 gtcaatcaat atgtagacat gctcattctt atggttacgc gatatatctg cgatcgctag
    45781 ctcgttctca ttcagcagag aaaatatctc tgctaatata ttggttttct tttgataaaa
    45841 tatagtgaat cgaaacggcg cttggaaaaa cattcgtgcg gatggataat tgaccgcttc
    45901 tctaaccgta ccgaacaaaa gataatcttt taaggcttca actgccaaac gtccgctgtc
    45961 tgccaaagct tcctgagtcg atcccctaga tgaggcaaca taagtatacg gtcattttct
    46021 aagaactctt cttctggaaa atcagtcaag tatttagcca gatgttgttt ttccaatgct
    46081 tgcataacag catatttatc aacaatttca cttcttccta cattgataag tacagcatct
    46141 tttttcattt tttctatatt cgcctgatcg atcaatcctt ttgtatcttc tgtcaacggc
    46201 agcatgacta cgatgtaatc cgaggtagaa agaactgttt ctaaatctgc ttgccgaaca
    46261 taatccaact gggcatcgcg gatagaataa cccaagacat ccatccctaa gctatagcaa
    46321 cttagcgcta cttttgtgcc tatcgctcca agaccaagaa gaccgatggt tttgccttgc
    46381 aattctcgtc ccacataagc acttcttttg ttttctgcct gttctaaaat attaggacct
    46441 gttagtgttt gtaccatacg acttgcttcg attatcggac gggaagataa gagcaaacag
    46501 cacaaaacaa gctcttttac tgcattagca tttacacctg gtgtattcat gacgatcgtc
    46561 ccgttttcag aagctttttc aacgttgatc gtgttcaccc caacaccagc tcttgaaatt
    46621 gctagcaaat ctggtgtaag ccattcatct ttcactttcg tactacgaat aactattcct
    46681 tcggctggca aatcatctat tattttgaaa tattcccctt gtaacttttc tatctcttgt
    46741 tctggaatag catcaatcaa atgaacgtga tacataaaac cccctcctta ctaacaagta
    46801 tctcgaaatt tctgcaatta gacaactgtt taccatttga cttcctagaa gcaaaaagag
    46861 cagttagagc agagtaggct gagtgataaa aataaggcta tgacaagtta ctgccataag
    46921 ccttattttc gagagcaaaa tattgagggt gagatatctt gataaatggt gttccgttag
    46981 ctgacattga taataagact aaatttcaaa aaagttgaaa agcaaatttc gtcaatctct
    47041 tcttatttct taaaactaag tggctttttc acaacctctt tttatctaat aaccactgtt
    47101 tccaactcaa ctaattttgc ccacgtttca atttgatctg ttgttagatt tagcgagaca
    47161 acggtatgat gaccgccacc tgcctgaatc catgaatgga caccttcatg gaaattcggt
    47221 ttagttttcc ataacacacg tgcaacaggt aaattaggtg cttcagtcgt tggttcaaag
    47281 gcttctactt cattgatcag cagtttataa tgcgtaccga aatctgccat cgatacgact
    47341 accccttctc ctgctttccc atcaaataca agacgcgccg gatcttctct atctcccatt
    47401 gataaaggag aaacaacgat tcttggtttc gtcgcagcaa gcgtcggatc tacttccatc
    47461 atatgggatt ccaagattgc ttcttggcca ctagctagct cgtaagtata atcttccatg
    47521 aatcctgtat ctttccctcg agccatgatt ttcagcaacc gatcaatcgc tgcagttttc
    47581 cagtcgcctt ccccagcaaa accgtatcct tctgccatca aacgttgtac agctagtcca
    47641 ggtagttgtt tcattccata caggtcttca aaattagtcg taaaagcgtt atagcctcct
    47701 tcttctaaga aacggcgaat accgatttcc tgctgagctt gtacttttac atgttcctcc
    47761 catgtctttt cttcataatc accatagtcg aaggtataca attccttgta ctcttcaaat
    47821 aattgatcga cttcttcgtc tgatacgcga tcgattactt gtacaagatc tccgatacca
    47881 aaataatcaa cagtccaacc aaattgaatc tgtgcttcca ctttgtctcc ttctgtgaca
    47941 cccacgtttc tcatgttgtc accaaaacga gccactttta ttccaaaact ttcattatag
    48001 gctactgcaa catccatcca atcagcaatc tctttttgga tctcaggtcg tttccagtag
    48061 ccaacgacga ttttattttg tttatttaat cgagcattga tgaacccata ttcgcggtca
    48121 ccatgagcgg attgatttaa attcatgaaa tccatatcga tcgttttcca aggaatgctt
    48181 tcgttatatt gcgtagctaa atgaagcaat ggtttttgta gaagctttgt cccgcggatc
    48241 cacatttttg ctggtgagaa agtatgcatc caagtgatca cacctgctac ttcttctcga
    48301 taattgacct ctttcatgat ttttgtgatc gtatcagcag taactgctaa ttcttgaagg
    48361 cggattggat aaggcaattg gccattttca ttcagttcat cgaccatttc ttgtgcatgt
    48421 ttctttactt ctcgcagtgc ttcttcccca tataaatgct gtgatcctac aacaaaccaa
    48481 aattcttttt ctccaatatt caacataatt agccactcct tttatttgtt ttgtccgtaa
    48541 tacgcatttt ttccgtgttt tcgtaaataa tgtttatcta aaatccgttg aggcagctct
    48601 tctgaaaatg aattgagctg tctggtaaat aaattcatct tgcatacttc atctagtacg
    48661 actgcgttca ttaccgcact ttgcgcatct ttcccccaag taaatggacc gtgtccgtgt
    48721 aaaagtaccc ctggaattgc taagggatca attttgcgtt ctttgaatgt ttctatgata
    48781 acttttcctg tttcatattc gtacccgctg tcgatttcct gttgtgtcaa aaatcgagca
    48841 caaggtaccg atccataaaa agtatctgca tgcgtcgtcc ccatcgcagg aacatccaat
    48901 cctgcttgtg cccagatcgt cgcccatgtc gagtgagtat ggacgattcc tccgatttga
    48961 ggaaatgaac gatataaaac agcatgagta ggcgtatccg aagagggatt gagtttacct
    49021 tcaatgatat gattgtccaa gtccacaacg accatgtcgt ctgctgtcat ctcttcataa
    49081 ctgactccgc taggtttgat aacgaaatat cgtgtttcag gatcaaaagc gctcacattt
    49141 ccccatgtat atttgacgag tccgtgttta ggcaagtcaa gatttgcttg gtatacttct
    49201 tctttcagtt gttccagcat tttctatcac tcctttttct tgcaattgat gaatcgctgt
    49261 tttttcaatg tcgatcccct cacggtaacg tctcataaat atctgatagc ctgctatttc
    49321 ttctgctgaa ggtgtgatgg tgattccttg gtcttgtcca aacacgtctt ctgccaagaa
    49381 gttttctaaa gacttcccat gtcgatccat catataggct gctaataacg cgattcccca
    49441 cgctccacct tctccggctg tgtccatcac tgtaactggt gcctccatag cagatgctag
    49501 aatccgctgt ccaacttctg gtgttttaaa aatcccccca tgccccacta aacgatcaat
    49561 ttggacattc tcagatttca atatatccat tccgattctc attgcaccaa aagcactggc
    49621 taaatggatc cgcatgaaat tcgctaaatc aaaacggcta cctggtgtac gtacaaataa
    49681 tggccttcct tcatttactc ctgtaatgtt ttcaccggaa aaataaccat aagaaagtaa
    49741 tcccccgcaa tccgtatcgc cttctagcgc tttgttgaat aataccgtga ataatttatc
    49801 tctgcttatc tccataccca aagaattggt aaattcttca aaaatactga cccaagcatt
    49861 gatatccgaa gagcagttat tcgtatgaac catgcctact agttctcctg aaggtgtagt
    49921 gaccatgtcg atttccggat ggacattttc tagttctttt tctaatacga tcatagcgaa
    49981 ggcggaagta ccagccgaaa tgttccctgt ccctttggct acactgttcg tagcgaccat
    50041 accggttcct gcatcccctt ctggcggaca aaccgggatt cctggtctca aatttcccgt
    50101 agggtcgatc agataagccc ctgattcgct taacttgcca gcttcttctc ctgctactag
    50161 aactttaggc aaaatgtgat ccaagtcaat cgctacgtgc gctttttcga ttaactgacc
    50221 aaaaatattt ttcatttctt gatggtaggt tttcgttgaa ggatcgatag gaaacatgcc
    50281 tgatgcatct cctacgccta gtactttctc accagtaagc tgccaatgga cataacctgc
    50341 aagcgttgtc aaaaaattaa tttctttcac atgttcttct ttattcaaaa tagattgata
    50401 caaatgagcg atactccatc tctgcggaat attgtattga aatttttccg ttaatattcg
    50461 ttctgcttct tcagtgattg tatttcgcca agtacgaaat ggtactagta actgttcctt
    50521 gctatcaaat gctagataac cgtgcatcat tgcactgaac ccaatcgacc cgattgtcgt
    50581 aagattctcg ccatagattt cgaatacttc tgctgccatt tttcggtaac tgacgcgcag
    50641 tcctttccaa atatcttcta atgaataggt ccagatacca ttttctagtt tgttttccca
    50701 ctcataacta ccagcggcaa taggagtaaa agatgaatca atcaatacag ctttgatcct
    50761 agttgatcca aactcaatcc ctaaagatgt acgaccatct atgacatcta acatactttg
    50821 cgcatttact tccttcataa tgatttaact ccctccttct cgtcaaacct gatcaaaccg
    50881 tctttttagt agcgcttaca atgattattg tatacttttg tacgtacatg tcaagcagtt
    50941 atttacaaga atacaataaa aaacacttgt tttgtacgta cataagttat aaaatgaaat
    51001 tgcttacaaa atctgatcaa ccgccttctc gaaattctag aaggagagaa tacttatgaa
    51061 aaaagaaaaa aaagtttcct catcgtttat ttattttttt ggcgcatttg gcggcattct
    51121 atttggatat gatattggtg ttatgaccgg cgccttacct tttttacagc atgattgggg
    51181 tttggcaggt aaagcttctt tgataggatg gatcacgtct tcggtcatgt taggtgcgat
    51241 ccttggcggc tctttatctg gtcttctttc tgataagctt ggacgacgaa aaatgattct
    51301 tctttctgca cttattttta tggctggttc tgtcctttct gcatctgccc ctcacaatgg
    51361 ttcttatttt ctgattgcag caaggattct tctaggttta gctgttggcg ctgcatctgc
    51421 cctagttcct gcttatatgt ctgaaatggc tcctgctaga ctaaggggaa gattgtcagg
    51481 gatcaatcaa gtgatgattg cttctggcat gctcctttcc tatgttgcag attatttgct
    51541 aaaagggttg cctgaaacga tggcttggcg cgtgatgtta gggctcgctg ctgtccccgc
    51601 gctgatttta tttttcggtg ttttagctct accagagtca ccgcgttttc ttatgcaatc
    51661 tggccgcttg gaagaggcaa aaagagtatt gaactatatt cggacaccaa aagaagctga
    51721 acaggaattc gaacaaatcc agctgaatgt caaacaagaa aagacaaccg gaacttcttg
    51781 gcatactttg tttttagaaa aatatcgttc cttagtcatt gccggtattg gtgtagcagt
    51841 attccagcaa tttcaaggag ctaatgctat tttttactat attccgctga tcgtagaaaa
    51901 agcgactggg catgcagcga gcgatgcatt gatgtggccg atcatccaag gaatcatttt
    51961 agttgctggt tctttgctct ttttggttat tgcagacaag ttcaatcggc gaactttatt
    52021 gaaaataggc ggtagcgtga tgggactttc tttcatccta ccagctgttt taggaactgt
    52081 actggatgct catacaaatt cgttgttgat tctcttgttt ttatgtattt atgtcgcatt
    52141 ttattcttgc acatgggctc cactgacatg ggtaatcgta ggcgaaatat tcccactagc
    52201 tgtccgcggg cgagcatctg gcctagcctc ttcttttaat tggattggtt ctttcctagt
    52261 tggcttgctt tttcctgtga tgactgcttc tatgtctcaa gaaatcgttt tcggcatttt
    52321 tgggatcatc tgctttttag gggttttatt tattcaagag atcgtaccag aaactcgtgg
    52381 gaaatcttta gaggaaatcg aacaaagtgc atctaaaaaa acttatccta aacgtatttc
    52441 tatccatcat tcttaaagag gttgtgacag aagtggtcag cttcaagaaa taagaaggaa
    52501 ccgcttagtt tccagtcaca aggaacaatt tcaaaaaaca gcttctcatg tttgatgaat
    52561 attgtgactt gtgaccagtt ggtaggagaa caccgtttag tggagaggtg gtgaaagaaa
    52621 cgttcagcct tgagcgatga caaaagctct cacaaacatt gcgacgagta accgtaggag
    52681 caataagagg cggtaaaaac ccgtctctta tttttcgttt tctttcactg tttcccgttc
    52741 aactagtaca ggttcataga gaatatttgg ctgtgcctgt cctttttcaa tcgttgtgac
    52801 gatccaccgt gcggcatctt gtcccaactt ttcttttgga tgcgtcaatg ttgtcaattt
    52861 tttattccct aaatggctta aagaagaatc gtctgttcct acgatcgata ggtcatctgg
    52921 aatatgatag ccattttctg tcaacttatc tagcattaaa ctagctattt gatcgttata
    52981 gcaaatgatg ccatctaaag cttgttcttc tttcaaccgt tgtactgttt tttcagcgat
    53041 tgtttctcgt gtttccgtgg tgaaagtaat gatatcttcc gtcaaaaaac gcacattata
    53101 ctgttcacac gcgctgataa aacctttcat cctgtatttt ccttgaagat cgtcgatttt
    53161 tgtgatgaac aacagacgct gatgtccttt ttttatcaaa tattctgctg ccataaaacc
    53221 gactttcaca tcatctaaac aaatataaga ggcatttaac tcttcataag cagcattgat
    53281 catcaccatc ggaatgcctt gttctctcaa agcaacataa agtgctaagt ttgggttata
    53341 ctgattactt ttcgtaggct caacgatcaa accatctacc ccataagcaa tcattttctt
    53401 caaacactct ttctccaatt cgtgatcgtt attcgtactg gctaaaagca atgaataccc
    53461 agattctcgt aattcatttt cgattcctcg gataatcgac ggaaaaatat aatcagagag
    53521 atatgtggtg atgacaccga tcgtttttgt tctgttcaat ggtgtttttt ctttcttata
    53581 gctgtcatct acatatgtgc ccgacccttt ttctttacgc agatagccct catttaccaa
    53641 cacagcgatt gcttgccgaa tcgtatgtct gctgacgtca tatatttctt gcagcttgaa
    53701 ttctgaggga atggttgtat ttacttcgta ttcctcacga aggatctttt gttttatctc
    53761 ttctgcaata tcttgatatt ttgccatttg ccttgcccct ttttatttgt acgtacatat
    53821 atcataacga gtctgcaagg tttattcaag caaaaatcaa ggtttcttgt gctcataagg
    53881 catacggaac aggttcacca aattctggaa atccttgctc attccacgta aagcattgcg
    53941 cgttcgcgtg ccgattagga ttgtctaacg gatccccttt ttggttcttc tctggtcgag
    54001 catgatagat caaaatatca aagcacccgt cttctgaaac cgtaaacgag ttgtgaccag
    54061 gaccaaattg cttatttttt tcagaagaaa cgaatactgg ctccgataat ttatgccatg
    54121 attcttttaa taaaagattc ttgtgctcat cagcccacag caggcccatg gcatagtttt
    54181 catctgttgc actaccagaa tacgtaatga atattttccc attgcgagta aggactgctg
    54241 gaccttcatt tactgaaaaa ccccgttttt cccattcata ctcaggtata gaaaggagga
    54301 tctgcttccc ctttaacgtc caaggattat ccatttcgga tagataaaga ttagaattcc
    54361 cagtaatttc aggatcttgt tgggcccaca cataatatag ctttccttga gaagagaaag
    54421 ttgttccgtc taaactgaaa gtttcccttt tcgtttttat ttgtcccttt tctatccaat
    54481 ctgtattcat tggatctata tgctgatttt caagtacgaa catgcggtga tgatgagatt
    54541 catcacgtat agttttatga ttgcttgcag caaagtaaat ataccatttt ccattgatat
    54601 aatggacttc aggtgcccag atcaattcac tcatcggtcc ttcttcatga gcctgccata
    54661 caatcaggct tgcagcatgt tctaattcat tcagtgactt tgcccttctt aattcaatca
    54721 cttggtagcc tggaaccgat cctgtaaaat aataataacc atctgtatgt ttatataccc
    54781 aaggatctgc ccgttgccga acgataggat tattataaag tgtcttcatc ataacaaatt
    54841 tcctcacatt ttctttattc taattacatt ccaagagtat ttttctatcc ctacatttaa
    54901 ttcgtcatgt ttttctattg aaaaatagtt tatttcaggt tttatttttt ctggttcttc
    54961 acgtgtattt ttgtccaaca gatcgctact ggttaatgtg tagtgctctc cttgatctag
    55021 caaattgaaa tcatgttcaa tcgttatctt ttgttgttca tttgtgcgat tgatcaagaa
    55081 aatagtcagc tgattgccgt tatctacgat cacactgtcc acataaggaa cattttttat
    55141 cttttcacaa tcataaacag ggcaaatgat ttgttgtttc aatacttgac ctttagcata
    55201 tttcgataag tgttgcatca cataataagt tggattcctc catgcttgtc ctttagcatc
    55261 tgtcagtatt aaaggtattg tgtttactaa caatgattga caactaatct ttacgcgatc
    55321 tgcgtgtcgt aaaatagcca gccctaatga accaaataat aatgtatctt ccatagtaaa
    55381 gtaacaccaa tcgatgggac taccgacttc aaaatcccta tgtctttttt ccggttgggc
    55441 atgtacattc cattcatcaa acgctagata cattgttttc tcacttctca aatatccttt
    55501 tacataatca caagtagcaa cgatttcttc aatttgacga tcgaatcgat aagcttttgc
    55561 aaggtatgtc gctgtatcat cacgctcatt tttaggaggt ttagtcaagt cttcttcatc
    55621 atacttatca atatagttat gcaaagctaa ataatctaca ttctcataag cttcttctaa
    55681 tgcgatacga tcccattcag ggtacgatgg taaacgtggc gtagagcttc caactaagat
    55741 tgtttcaatt gaatcatcca ctaacttcat gacttttgag gcttcatttg ctaacctacc
    55801 atattcataa gcactcttag cccccacttg ccatggaccg tctagctcat tccctaaaca
    55861 ccataattta acgccaaaag gctttttttg cccatttttt attcttaaat cactccagaa
    55921 ggttcctttt ggaaaattac aatattctac taaatttttt gcttcatcaa ttccttttgt
    55981 tcctaaattc accgtgaata tcggtttcgc ttgtacatga ctgatccatt taaaaaattc
    56041 gtggagtcca aaagaatttg gttctatacc tcgccatgct aaatcaattt tttttggtcg
    56101 ttgttctttc ctacctacag tatccaccca atcataacca gatgtaaagt ttcctccagg
    56161 atagcgaatg acacctaatt ctaattcctt tacataagag aggacatctt gtctaaaccc
    56221 gtcaccatca gctgtttcat ggcccggttc ataaatccct gtatagacga cacttcccat
    56281 atgctcaaca aatgagccaa acagccgaga actgatctct cctaccgtaa aatcctctct
    56341 gatttttact ttcacttctt cgtccaacag ctttccctac ctttcatttc ctatagtcaa
    56401 gataatagat acaagtttcc atacgccacc agcaaagata aaaataaaag gagggaaaag
    56461 aaatatgagc agtacaaatc ctaataacaa tacgcaacaa agaatatttc tcaaaaaatc
    56521 aaaaaatact ttccatgcac tttgttcaaa aatttgtaaa aatgtgatat ctttgttttc
    56581 agaaatcaca tatatccagg ataaaagaaa catggaataa ataagtaaaa ctacatatcc
    56641 actaattgaa agtacgattg tctgttcttc taataattga ttaacaagaa aataaataat
    56701 gatcgttaac agactaagga acaagttctt accaaaatgt tgctttattc cttgaaagaa
    56761 aaaataaatg atatttcctg atccctcacc tttccattgc gccattacat aaaaaacagc
    56821 acatgtagca ggcacgatag taataacagg caaacacacg attacccaga gaatacctaa
    56881 taagatgtaa tcagaaacca caatcaactg tccataaagt ttagtctcaa ctattttcat
    56941 cttcctcact ctttcattcc agacatagct gttccttgaa caaaatattt ctgtgcaaaa
    57001 atataaacca ctagtaatgg cagcattgaa ataaccgttc cagccattac aggtccataa
    57061 aaagaaatgt tctgccctgt aaataaagct aaccctgctg gtaaagttct catttttgaa
    57121 ctacttgtca atatcaatgg ataaagcaag tcattccaac tattcatcag cgtgaaaatc
    57181 cctaatgata aaagagtagg tttgctcaat ggcaacatga ttttcaaaaa aatattaaac
    57241 tcacttaatc catcaatgcg tgctgcctct tccaaagaat ctggtaaagt aataaaaaag
    57301 gaacgcatca tgaagatacc aaatgcagtt gtcatacgag gaatgatcaa acctgcataa
    57361 gtatcaagca tgccaagcaa attgacttca ataaatagag gaatcatgaa gacttggaat
    57421 gggatcatca ttgtcagcaa aacgaaatag aacaaaactg attttccttt gaaacgcata
    57481 cgagcaaatg cataccccgc aagagaatca aagaatacag aagtgatcac tgtccctcca
    57541 gcaaaaatca ctgtattttt gatgtaatct aataaaggga tcgttgtcca aaccttaata
    57601 tagttatcta gggtatagct atctgcaaat attctaggcg gaaatgagat aatgtctttt
    57661 tcgtgtttaa aagaagaaat aatcagccac aaaaaaggaa acgcaataac caacaatata
    57721 actagcatac taatcgttcg aatgattttt ttaccactaa ctgcttttcg actattcaca
    57781 gtaactgtaa tcgagctttc tggtgccata caggtttccc tcctatttca tttgtttttc
    57841 tttccgtgac atgtacacat tagtggagat agctatagtt gcaacaatga taaacaaaac
    57901 cgaagacagt gctgatgcat agcccaattc ataaggtgct gtaaatcctc gactgtaaat
    57961 atattgaaca gctgtttctg tcttaaattg tgggccacca gcggttgcaa catatacttg
    58021 gtcaaacact tgcatcgaac caatcagatt cgttaaaata caaaaaccta aggagggaac
    58081 gatctgaggt agcgtaatgt taaaaaactg ctgtcgattt gttgcaccat ccatttgagc
    58141 agattcatac aaagagggag agattccctg aatagcagtc aagagaatcg tcatagtaac
    58201 accaaaattc ttccaaacag tcatgatggc taccgtcggc atagcaaggg ttggatcgcg
    58261 aaaaaattga gggatcggca agccgacttg tgaaaacaag taaggaatcg cccctacatt
    58321 cggatcaagc aacatagaaa aaataatcgc aattgacgtc aatgaacaaa taactggaat
    58381 gtaaaatgtc gaacgacaaa aacgattgaa tctggtattt ttagataatg ctactgctgc
    58441 taataaacca acgataattt gtgttggcgt ttcgagtacg gtgaaatata aagaatgaat
    58501 caacgaatta actgctcgtt catcactaaa tatacgtgtg aaattttcaa aacttacaaa
    58561 atttcttgat gtaaagaaaa tattcaaatc tgtaaaacta atagcaaatg ttcctaaaag
    58621 cggtatgaca gtaaataata ataaaactaa aaaagatgga gttaaaaaca aatacgcagc
    58681 acgatcagga cgattccaat atttggtgaa tccgttcata tagtccacct catctttcat
    58741 tttgataaaa tatacaatct tggtttaaac gaatctgaat aagatatccg aacaatcgct
    58801 gtgatttttg caataacacc tatctgcaaa tactaggtcg atcattcaga tatctgtatc
    58861 ttgccaacag tctatcctgt ataaagttct gtactatttt tgcagtaatt gattgatggc
    58921 atcatctgca tcgttcatga gtgtctcagg atcttctcct gctaataatt tttcaatcag
    58981 tggattgatg atatcgttat tgatcgcaga gatttgggta aaacctggta aatatggctc
    59041 tgcatagtcc atttgtttcg ataattcaga tacaatagga tcatttttta cttcttcatc
    59101 ttttgctact gaatccaagt aggcaggaaa accattttcg atactccatt ttttaccaat
    59161 ttcagttgta ttccaatatt tcaaaaactc atagacagct tcttttttat tattatctgt
    59221 acttgccgga atggcatatc ctacgccatc taaaatagct gtttttttgt ctgaatcact
    59281 cccttgtggt aaggtagtca cattataatc aatctcgttt gctttcaatc cgttatttaa
    59341 ccatggccca ttgatttcaa tggctagttg accagcattc attaaattgt ccatttcggc
    59401 gccagaaatc gattctggac cagtcttgtc tacatggatc attttttgga tcgcttttaa
    59461 cgttttaagg ttctcaggag acgcaaattc agacttagta taatcatcgt tcactaattt
    59521 accgccattt gctaacatcc agttatataa cggtgcagtt ccatccttat tgaagacaaa
    59581 acctgataca tttttactac tatcagttaa ttttggtgcc atttctgtca attcttccca
    59641 agtagtaggt ggttgttcag tatctaatcc agcttgttta aacaaatcat tattccaata
    59701 catatacatg ccttgtacct gcatggggac aaaatactgt ttaccttcta cttcacctaa
    59761 ttcaatagcc gtttctttaa aatcagattt atctactcca tcatattccc agaaatcgtc
    59821 taatggttgt accgctccgt tttctacata ctgtgcaaaa tctggataat ttaatgcaat
    59881 aaagtcaggt gcttttttag aagaaatcgc tgtaggaagt ttttcattca aattggccca
    59941 agtcatgata tccatttcaa ttttgatgtt tttatcattt gttttattaa attcattaac
    60001 gatttcttgc aatatttcac catcagatgc agtaaaccca ttccaaaaag tcaaagtcac
    60061 ttctttatca gaatcagatt ctgctgaact tccgccaccg caagctccta aaatacctgt
    60121 tgcagctacc aacaaagagc caattaacca ttttttacct ttcatttttt gttcctcctt
    60181 catctgataa acgacatctg accacattcc aagatagcgg tttcaataaa caattgattt
    60241 tcccatcttc agcttttaca tttgttgaat gacttggttt tacttgttca cttttaggaa
    60301 gattagttgc ttttgtatca aatccactca tttcagaaaa atcaatcact ccctctaatg
    60361 ataattcaga caagtgaaca gttagattca tttcttcttc tccacggtta actgcaaata
    60421 tgacaagttc tttgtcattt attacggcta tactttctaa atacggcact tcttcaaaat
    60481 cttccgtcgc atagtttgct gaacgaattt gtgggcttaa cacctctcct tgtccataca
    60541 cagcagcttg cataaatgga taatagatcg tctgtctcca agcttctccg tttgtttctg
    60601 tcctgattgg tgcaataaca tttaccaatt gagcaagaca agcaatcttt actctatctg
    60661 catgtttcaa taaagtgatt aatagacagc ctaatagtaa tgcatcttca aaattatagt
    60721 tatcttctag taaaggagga gcaatctgcc aaggcgctgc ttgctcatct tgttccgctg
    60781 aatgatacca aatattccat tcatcaaagg acaggttgat ctgcttctta ctatgtttct
    60841 tcgccttgac tgtatcgcac atcgctgtca cttcagaaat gaaccgatcc atgtctaagg
    60901 aacgtgcaag ataatgagaa agatcatttt tttggttgcc ataatattga tgcagagaca
    60961 aataatctat ttgatcgtac gcttgatcaa gaactgttaa ctcccaatca ccaaatgtag
    61021 gcatttgccg attcgaactt ccgcataaaa ccacctcaat tgaatcatct acgagtttca
    61081 tcgccttagc cgtttcctct gctaaccgtc catattcttc cgctgtttta tgtccaatct
    61141 gccaaggacc gtccatttca ttccctaaac accatgtctt aattccaaaa gggctctctt
    61201 gaccattcga acgccttaaa tcactccaat aagttccttt aggaaaatta caatattcga
    61261 ctaaattacg agctgcatct actccacgag tacccagatt gacagccata ttgatttcgg
    61321 cccccacatg ctgacaccag ttataaaatt catgaatccc aacttcattc gtttcaattg
    61381 tccgccaagc taaatccaac cttctaggtc tatttgctat gggcccaata ctgtcttccc
    61441 aacgaaatcc tgacacaaaa tttccaccag gatatctaat catgggaatg ttcaattctt
    61501 ttaccaagtg aatgacgtct tggcgaaatc cacttttatt agctgatgga tgatctggct
    61561 gataaatccc ttcatatact gctcgtccca tatgttcaat aaatgaactg tacaaccgcg
    61621 gatcaacttt gcctacacgc ttgacactac taatcaacat tgtggcttcc ataactgacc
    61681 tcctttaatt tatacatgaa taatacacct cgttgaaagc gttgtcaata atataaatgt
    61741 taaacttact tattttttat cgattttaat taaccaaaat attaataatg attaaaacaa
    61801 ataatttaat ataactttta ttaacaaata tgttaatata taagaaaaac cttttaagag
    61861 gtgatatata tgcaactaca aataaacgaa gaatccttac cggtatatga agcattagct
    61921 agtaaaacaa ggatcaagat catccagcta ctttccaaaa aaaagatgaa tgtcaaagat
    61981 ttggcaaaag aacttggagt gagcagtgct atcacgacga tgcacgtgaa aaagctagag
    62041 gaagcaaaca tcatcaaaac agaaaaagta ggacaacaaa aaatttcgag ccttcgtgtc
    62101 gataaaatcg atatcagttt tccagaaaaa atattcaatg cttttgatac gaaagaaaca
    62161 tcgataccta ttggtcacta tacaaattat gcaattgaac caacatgcgg tttagctacg
    62221 atccatgatt ttatcgggaa agtggatgaa ccacgctatt ttatggatcc tcgaaggatg
    62281 gatgcccgca ttctctggtt taccagcgga tttgtcgagt atcaggcacc taatttttta
    62341 aatacagagg atacattgga gatgttggaa gtttctgtgg aaatttcttc tgaatttcct
    62401 ttttcaaatg acaattggcc ttcagatatc actttcagcc taaatggtgt ggagctagga
    62461 acatggacga gccctggaga ttttgctgat atccgcggta aatatacgcc tgattggtat
    62521 ccagataatc ttaatcaata cggcttgctg aagacgatcc gaattaccaa acacttgacg
    62581 aatatgaatg gagaaccctt gtcaaacatc acgatcaacg acatccctaa agagcaagac
    62641 acttggcatt tgcgaatcga agtgaaagac gatgccaaac atgtgggggg ctgtacttta
    62701 tttggtaaag gattcggtaa ttacgatcag gatatcaaat taaaagttta ctacagctga
    62761 tatttttctt ttctatttta taaaacaaaa acagccaatc cctatgaagg gacggctgtt
    62821 tttgctttat tgttatttcc agaaatcatc caaaacggaa attggcaaat gtcgtttatg
    62881 ttgtgtcttg ttccaccatg cttcgatttt ttcttgtgct tgagcgggaa cttcttttcc
    62941 ttctagataa tcatcaattt cattatatgt gacacctagt gcgacttcat ctgcaatcat
    63001 tggtttccca tcttcaagat ctgcagtcgg aatttttgtg tataattttt ccggtgcatt
    63061 caatgcttga agcaattgtt tcccttgtcg tttgtccaaa cggaataatg gcaaaatgtc
    63121 ggctccacca tcaccaaatt tcgtgaagaa tccagtaatg ttttctgcag catgatctgt
    63181 ccctaatacg gctcctgctc tttctccagc tacggcatat tgcgtaatca tacgttgacg
    63241 tgctttgata tttcctttgt taaaatcgct gattcccaca cctgcttcgc ttaatacttg
    63301 tacttgtgca tcaacagctg gtttgatatt tactcgcaga ctaacatcgg gctggataaa
    63361 gtcaagagca gcttttgcat cttcttcatc tgcttgttca ccataaggaa gacgaacagc
    63421 gataaattga tagttttcat cttttgtttc ttcacgcatt tcttccatcg ttagttgcgc
    63481 caaacggcct gctaaagtag aatcttggcc gccgctgata cctagtacaa aagttttaag
    63541 aaacggatat tttttcaaat atgctttcat aaagtcaata cttttacgta tttcttcttt
    63601 tggatcaatt gttggtttga cacctaattc attgataatt tctgtctgca ggctcattta
    63661 ttctcctcct atgcttctgt atgaagttct gctacgcttt ttttcattcg ttccatgata
    63721 gccattttat ggttccagca ttcagtagac agatcgactg ggtatttttg cggattcaag
    63781 tctcgtttat actcttccca tagtgaatct agattttctt ttgtatattc tttgatttcg
    63841 tttagtgcag gtaattcgta aactcttttt ccttcgataa agatatcttg taaaactggg
    63901 cgagctgtaa agtctcgaac agttttattg ataaacgtat gcactggatg gaacatgaag
    63961 atagcttctt cttctcgagg gtcttcatcc cataatgtca cgtagtctcc ttcagatttc
    64021 ccatcaaaat ttcgagtgat gcgccacact tgttttttcc ctggagtagt tactttttct
    64081 gcattgcttg ataacttgat cgtatccatc atttttcctt catcatcttc gatcgatact
    64141 agcttgaata ctgcaccaag ggctggctga tcataggctg tgatcaattt tgtcccaaca
    64201 ccccatacat caattttagc tttttgcatc tttaaattca aaatcgttgc ttcatccaag
    64261 tcattcgaag catagatttt tgcttccgta aatccggctg catctaattg ttcccgaaca
    64321 cgcttagata tataggccat atctccactg tcgatgcgta cgccttggaa gttgattttg
    64381 tcacctaatt ctttcgccac gcgaatcgca cttggcacac ctgatttcaa cgtatcataa
    64441 gtgtcgacta agaacacgca gtctttatgg gttttagcgt aggccataaa tgcttcataa
    64501 tcatttccat aagattggac taacgaatga gcatgggtcc cgctagctgg tatcccaaat
    64561 atcttcccag cacgtacatt gcttgttgca tctgctccgc cgatatatgc cgctctagtt
    64621 ccccagactg ctgcatccag ttcttgtgcc cgtctagttc caaattccaa tagtggatct
    64681 tctccgatga cagatttgat acgagctgct tttgtcgcga tcaacgtttg gaaattgacc
    64741 atattcaaca gtgctgtttc tactaattgg cagtgcgcta aaggcccttc cacttggatt
    64801 aatggttcat ttgcaaaaac tagttctcct tcacgagcag aacgaactgt tgctttaaat
    64861 tcaaaatttt gtaaatactc caaaaaacct tcaggataga cttctaatcc acgcaagtaa
    64921 gcaatatcgg aatcattgaa cgtcagattc tctaaataat tgactaaccg ttccaatcct
    64981 gcaaaaaccg cgtatccgtg gttaaaaggc atttctcgaa agtaacattc aaaaacagca
    65041 tgtaaatcag ctcgacctaa ttcccagtat gtctgcatca tattgatttg atatagatcc
    65101 gtatgcagcg tcaaactgtc gtctgggtaa gtattattca tcttgtatta ctcctcttgg
    65161 caagttttca tttcctaccc attataacaa aaaaaattaa taggaaaaga aatcttccat
    65221 tttttctgaa aaagcacatg ttttacggat atttcttgct aaaaatgaac tccatctgct
    65281 aaaactatcc tttcttattg gtatttaacc taaacgagaa agaatactta ttttattcaa
    65341 tgtatccgag acacgaagaa attagcgttt tctatttttc ttacttgata aaataagtag
    65401 attttcctac tacaatcgta gccgttaaga taccgatgat tgaacaaata taaccaaatg
    65461 tctctacaac ataatcaatg gcaaaagttt ttgaagcaat aatacgtctt tccttttttg
    65521 cttcttatcc ccaaagaaac ggatataact tattatgtat tgaatttttt tggaaaggcg
    65581 aattatgaca agatatacct tgcgttgaaa aaactcgcgg aaaaaatatc acacgttttt
    65641 aaaaagatac aaagtaagaa agcagctgtc aatagaatgg aaacaaaaat ggcgagacat
    65701 caatcagtct cgccttgttt tttattgtat acattagata tggagcaggt taccataaag
    65761 atgattatta gtcgttatta aatagaatcc ttcgtatttt tttgttctat cactacaata
    65821 tctttatttg gacgtttgaa ttgtattccg gcacgttcta gctcctgttt cactcctaca
    65881 tggactttga catcttctcg tgtcattttt aaaacgtgat gaatcgcata gtcgatttct
    65941 tgccttgtga tttttttctt cgtattgatc atcacgactt gctttttatc atatgtgtct
    66001 accaatagca gttgtgttcg atctaacgaa aataatttgt aataattaat agccgtattc
    66061 ccaaaaaaga attccactac tttaggataa aatgtcttaa tatttaaatt actattcaca
    66121 ggtgtttcga ttagcttcat ctcattcctc ttttctatat agtcgattta gatccaatct
    66181 taagttatgt taccatcttt cctagcatta aggaatcggt tacaattgaa cctttaaaga
    66241 caaaaggatt taccttttat cacttaatag tataacataa tttcgtgaga aaaaaataca
    66301 attttttctt gaccatctcg ttacgtaaag gattatgctt acatttgtca ggaggaaaaa
    66361 taatggagta cacaataaag aaaatgtcag agatatcagg agtcagtccg agaaccttgc
    66421 gcttttatga tgagattgga ctgctaaaac cagctaggat caattcttca ggttatcgga
    66481 tttatggcaa aaaagaagtc gatcgtctgc aacacatctt attttatcga acaatggcat
    66541 tcaagttgga tgatatccaa gaggtcttag acaatccatc ttttgaccac cagaaagctt
    66601 taatcaagca tcagcaaatg ttgctggaaa aacgggcaca aatcgatacc ctcttgacaa
    66661 ctgtccaaca gacacttgat atgtacgaag gaggaagaaa aatgagtgac aaagaaaaat
    66721 ttgaagggtt taaacaacaa aagttgaaag aaaatgaaga atcctatgga caagagattc
    66781 gacaaaaata cggaaaaaaa aaggttacag catccaatga aaaatggatg aatatggata
    66841 aagaaacgta tgaagaaatg caaactgttg aaaagcagat gttatttgat ctcactcttt
    66901 acttaaaaga accagaagat gaaagcttag cagaccgtat cttccaagct cataagaagt
    66961 ggttctctta cagctggcct gaatatcagc caaaagcgca taaaggacta ggaatgatgt
    67021 acgaagccga tgaacggttc actgcatatt atgacgagcg aagtggtcat ggtgcagcaa
    67081 aagctttaaa tgaaattatc caaaaaaagg cgtaatcttt tacatgatcc aacaaaaaag
    67141 tacacgtaaa atgacctaat aacaaaacag cagacaccca agttagattt ttatgctaac
    67201 ttttggtgtc tgctccattc tttcacaagt tttttcatcc tactttaaat atattcatcg
    67261 ttgaataaac gtataaggta ttttcacttt atcctttttt tctgtaagaa acaattgaaa
    67321 tgccatttct ccgcaagctt ccagatggtg gtcgatggtt gggaaaccaa gaagctcgct
    67381 gatcagcaaa ttatcgcgtc caatcaccac tggtgtctta tcttgcagat agctttgcaa
    67441 gatgcctgct gcaaccatat ccgaatttgt aaagacacca tcaactccaa gctctttaaa
    67501 aaagaagcct gcttgttttc ctttctctgc atctatacaa tcccaaaaaa caagtgattc
    67561 atcaaaagat ggaaaaagtt gatgacatag ctgcaaagtg atttttgagt tataacttag
    67621 cctgccactt cgccccaacg tgatgcccaa ttgctttata ccttgctgct tcaaataagt
    67681 aagaccttct gtaattgatt gttctcgatc aataaagaca cagcttgcct gttttccctt
    67741 gatttcttca caaaaaacta gaggtccata tttttgatat gccaataaat catctagtgt
    67801 attggcacga gacgtaatga tcaatccatc gaaagcttta gctgcaaatt cttcaagata
    67861 ccttcgctct ttttctttat gatagcccgt cggtaaaagt gtcactttgt aatcataatc
    67921 aaacgctgct tcaatgatcc cactgatcaa ctgatcaaaa tacggatgat tggtataagg
    67981 cagaatcact ccaatgcttt tcgtttttcc ataacttaac tgtctggcat ttgcattagg
    68041 gatataatcg acttctttca tgaccgcaag tatttctttc cttttttcct catctacata
    68101 tggatgtcca ttgattacac gtgaaatagt agaaactgaa taacctgtga gctttgcgat
    68161 atctcgaatg tttgccactg ctgcttcgcc acctatacaa aaagattttc ttgtaaatag
    68221 tctaccacag ctggaccgca ttcaaaaaac tgatacattt ttccttcatg cgaaaaactg
    68281 atccgctgcc cgccccaata tatatctttt gtcaaatttt cgatttcatt cattggtatt
    68341 tcttttacta tattcctatt caacccttga aaactgtaca acgttaatac ggatcccttg
    68401 aactcgacaa acgcataaaa ataattgttc gttgtgccat ctgttatctc tacataagta
    68461 ttcattgcaa gccctccttt tgatactttg agtatagtgt atgaaacgcg tctcatagca
    68521 aggagtttgt tttgccaaag aaaagtttta ttcctctttc attattacca aagtctctta
    68581 ttttaaattg aatacattat aatgatactg taaatatatc tttattatta gtgaatg
//
LOCUS       DAXQKX010000008        64811 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.008, whole genome shotgun sequence.
ACCESSION   DAXQKX010000008 DAXQKX010000000
VERSION     DAXQKX010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 64811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64811
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.008"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..420
                     /locus_tag="ACF3MF_000571"
     CDS             <1..420
                     /locus_tag="ACF3MF_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HFE3926596.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(504..1226)
                     /locus_tag="ACF3MF_000572"
     CDS             complement(504..1226)
                     /locus_tag="ACF3MF_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFE3926597.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(1216..1953)
                     /locus_tag="ACF3MF_000573"
     CDS             complement(1216..1953)
                     /locus_tag="ACF3MF_000573"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3926598.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            complement(1965..2957)
                     /locus_tag="ACF3MF_000574"
     CDS             complement(1965..2957)
                     /locus_tag="ACF3MF_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFE3926599.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            complement(2972..3715)
                     /locus_tag="ACF3MF_000575"
     CDS             complement(2972..3715)
                     /locus_tag="ACF3MF_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFE3926600.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     regulatory      complement(3789..3893)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(3956..5278)
                     /locus_tag="ACF3MF_000576"
     CDS             complement(3956..5278)
                     /locus_tag="ACF3MF_000576"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFE3926601.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     gene            complement(5265..6230)
                     /locus_tag="ACF3MF_000577"
     CDS             complement(5265..6230)
                     /locus_tag="ACF3MF_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3926602.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            complement(6227..7765)
                     /locus_tag="ACF3MF_000578"
     CDS             complement(6227..7765)
                     /locus_tag="ACF3MF_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HFE3926603.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            complement(8181..8468)
                     /locus_tag="ACF3MF_000579"
     CDS             complement(8181..8468)
                     /locus_tag="ACF3MF_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926604.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            8602..9270
                     /locus_tag="ACF3MF_000580"
     CDS             8602..9270
                     /locus_tag="ACF3MF_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFE3926605.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            complement(9561..10301)
                     /locus_tag="ACF3MF_000581"
     CDS             complement(9561..10301)
                     /locus_tag="ACF3MF_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926606.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(10431..11378)
                     /locus_tag="ACF3MF_000582"
     CDS             complement(10431..11378)
                     /locus_tag="ACF3MF_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFE3926607.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            complement(11507..12271)
                     /locus_tag="ACF3MF_000583"
     CDS             complement(11507..12271)
                     /locus_tag="ACF3MF_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFE3926608.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            complement(12275..12664)
                     /locus_tag="ACF3MF_000584"
     CDS             complement(12275..12664)
                     /locus_tag="ACF3MF_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926609.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            12799..13341
                     /locus_tag="ACF3MF_000585"
     CDS             12799..13341
                     /locus_tag="ACF3MF_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HFE3926610.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            13489..14121
                     /locus_tag="ACF3MF_000586"
     CDS             13489..14121
                     /locus_tag="ACF3MF_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926611.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(14255..14380)
                     /locus_tag="ACF3MF_000587"
     CDS             complement(14255..14380)
                     /locus_tag="ACF3MF_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HFE3926612.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(14514..15407)
                     /locus_tag="ACF3MF_000588"
     CDS             complement(14514..15407)
                     /locus_tag="ACF3MF_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HFE3926613.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(15589..16515)
                     /locus_tag="ACF3MF_000589"
     CDS             complement(15589..16515)
                     /locus_tag="ACF3MF_000589"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HFE3926614.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(16600..17361)
                     /gene="pflA"
                     /locus_tag="ACF3MF_000590"
     CDS             complement(16600..17361)
                     /gene="pflA"
                     /locus_tag="ACF3MF_000590"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HFE3926615.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(17605..19836)
                     /gene="pflB"
                     /locus_tag="ACF3MF_000591"
     CDS             complement(17605..19836)
                     /gene="pflB"
                     /locus_tag="ACF3MF_000591"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HFE3926616.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(20113..22563)
                     /gene="parC"
                     /locus_tag="ACF3MF_000592"
     CDS             complement(20113..22563)
                     /gene="parC"
                     /locus_tag="ACF3MF_000592"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HFE3926617.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(22575..24620)
                     /gene="parE"
                     /locus_tag="ACF3MF_000593"
     CDS             complement(22575..24620)
                     /gene="parE"
                     /locus_tag="ACF3MF_000593"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HFE3926618.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(24786..25220)
                     /locus_tag="ACF3MF_000594"
     CDS             complement(24786..25220)
                     /locus_tag="ACF3MF_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HFE3926619.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            25347..25985
                     /gene="plsY"
                     /locus_tag="ACF3MF_000595"
     CDS             25347..25985
                     /gene="plsY"
                     /locus_tag="ACF3MF_000595"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HFE3926620.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(26117..26992)
                     /locus_tag="ACF3MF_000596"
     CDS             complement(26117..26992)
                     /locus_tag="ACF3MF_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HFE3926621.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(27074..27865)
                     /gene="codY"
                     /locus_tag="ACF3MF_000597"
     CDS             complement(27074..27865)
                     /gene="codY"
                     /locus_tag="ACF3MF_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HFE3926622.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(27883..29283)
                     /gene="hslU"
                     /locus_tag="ACF3MF_000598"
     CDS             complement(27883..29283)
                     /gene="hslU"
                     /locus_tag="ACF3MF_000598"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HFE3926623.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(29297..29845)
                     /gene="hslV"
                     /locus_tag="ACF3MF_000599"
     CDS             complement(29297..29845)
                     /gene="hslV"
                     /locus_tag="ACF3MF_000599"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0004298 - threonine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HslVU peptidase proteolytic subunit"
                     /protein_id="HFE3926624.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(29882..30787)
                     /gene="xerC"
                     /locus_tag="ACF3MF_000600"
     CDS             complement(29882..30787)
                     /gene="xerC"
                     /locus_tag="ACF3MF_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HFE3926625.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(30985..32361)
                     /gene="trmFO"
                     /locus_tag="ACF3MF_000601"
     CDS             complement(30985..32361)
                     /gene="trmFO"
                     /locus_tag="ACF3MF_000601"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047151 - tRNA
                     (uracil(54)-C5)-methyltransferase activity,
                     5,10-methylenetetrahydrofolate-dependent [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HFE3926626.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(32330..34408)
                     /gene="topA"
                     /locus_tag="ACF3MF_000602"
     CDS             complement(32330..34408)
                     /gene="topA"
                     /locus_tag="ACF3MF_000602"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HFE3926627.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(34530..35387)
                     /gene="dprA"
                     /locus_tag="ACF3MF_000603"
     CDS             complement(34530..35387)
                     /gene="dprA"
                     /locus_tag="ACF3MF_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HFE3926628.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(35443..36210)
                     /locus_tag="ACF3MF_000604"
     CDS             complement(35443..36210)
                     /locus_tag="ACF3MF_000604"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HFE3926629.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(36203..37063)
                     /gene="ylqF"
                     /locus_tag="ACF3MF_000605"
     CDS             complement(36203..37063)
                     /gene="ylqF"
                     /locus_tag="ACF3MF_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HFE3926630.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            37323..37721
                     /locus_tag="ACF3MF_000606"
     CDS             37323..37721
                     /locus_tag="ACF3MF_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFE3926631.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            37958..38500
                     /locus_tag="ACF3MF_000607"
     CDS             37958..38500
                     /locus_tag="ACF3MF_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HFE3926632.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(38583..39134)
                     /gene="lepB"
                     /locus_tag="ACF3MF_000608"
     CDS             complement(38583..39134)
                     /gene="lepB"
                     /locus_tag="ACF3MF_000608"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFE3926633.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(39286..39513)
                     /locus_tag="ACF3MF_000609"
     CDS             complement(39286..39513)
                     /locus_tag="ACF3MF_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HFE3926634.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(39510..40028)
                     /gene="msrA"
                     /locus_tag="ACF3MF_000610"
     CDS             complement(39510..40028)
                     /gene="msrA"
                     /locus_tag="ACF3MF_000610"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFE3926635.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(40048..40761)
                     /locus_tag="ACF3MF_000611"
     CDS             complement(40048..40761)
                     /locus_tag="ACF3MF_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HFE3926636.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(40764..41660)
                     /locus_tag="ACF3MF_000612"
     CDS             complement(40764..41660)
                     /locus_tag="ACF3MF_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFE3926637.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(41818..42660)
                     /locus_tag="ACF3MF_000613"
     CDS             complement(41818..42660)
                     /locus_tag="ACF3MF_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFE3926638.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            42792..43445
                     /locus_tag="ACF3MF_000614"
     CDS             42792..43445
                     /locus_tag="ACF3MF_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HFE3926639.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(43508..44035)
                     /locus_tag="ACF3MF_000615"
     CDS             complement(43508..44035)
                     /locus_tag="ACF3MF_000615"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HFE3926640.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(44055..45002)
                     /locus_tag="ACF3MF_000616"
     CDS             complement(44055..45002)
                     /locus_tag="ACF3MF_000616"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004799 - thymidylate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006231 - dTMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HFE3926641.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(45014..46897)
                     /locus_tag="ACF3MF_000617"
     CDS             complement(45014..46897)
                     /locus_tag="ACF3MF_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFE3926642.1"
                     /translation="MKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKTS
                     LLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVRA
                     YEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIST
                     LSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDRY
                     FLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMRA
                     GVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRINDQ
                     TLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQE
                     NEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEKR
                     RLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVAD
                     KLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKEW
                     ETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSEW
                     VED"
     gene            complement(47060..49138)
                     /locus_tag="ACF3MF_000618"
     CDS             complement(47060..49138)
                     /locus_tag="ACF3MF_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFE3926643.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            complement(49151..49426)
                     /locus_tag="ACF3MF_000619"
     CDS             complement(49151..49426)
                     /locus_tag="ACF3MF_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926644.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(49788..50243)
                     /locus_tag="ACF3MF_000620"
     CDS             complement(49788..50243)
                     /locus_tag="ACF3MF_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926645.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(50397..51605)
                     /locus_tag="ACF3MF_000621"
     CDS             complement(50397..51605)
                     /locus_tag="ACF3MF_000621"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HFE3926646.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(51717..52049)
                     /locus_tag="ACF3MF_000622"
     CDS             complement(51717..52049)
                     /locus_tag="ACF3MF_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HFE3926647.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            52197..53072
                     /locus_tag="ACF3MF_000623"
     CDS             52197..53072
                     /locus_tag="ACF3MF_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFE3926648.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(53154..53735)
                     /locus_tag="ACF3MF_000624"
     CDS             complement(53154..53735)
                     /locus_tag="ACF3MF_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ReoY family proteolytic degradation factor"
                     /protein_id="HFE3926649.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(53741..55000)
                     /locus_tag="ACF3MF_000625"
     CDS             complement(53741..55000)
                     /locus_tag="ACF3MF_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFE3926650.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(55002..56048)
                     /locus_tag="ACF3MF_000626"
     CDS             complement(55002..56048)
                     /locus_tag="ACF3MF_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926651.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(56283..56558)
                     /locus_tag="ACF3MF_000627"
     CDS             complement(56283..56558)
                     /locus_tag="ACF3MF_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HFE3926652.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(56801..58111)
                     /gene="der"
                     /locus_tag="ACF3MF_000628"
     CDS             complement(56801..58111)
                     /gene="der"
                     /locus_tag="ACF3MF_000628"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HFE3926653.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(58293..59522)
                     /gene="rpsA"
                     /locus_tag="ACF3MF_000629"
     CDS             complement(58293..59522)
                     /gene="rpsA"
                     /locus_tag="ACF3MF_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HFE3926654.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(59657..60337)
                     /gene="cmk"
                     /locus_tag="ACF3MF_000630"
     CDS             complement(59657..60337)
                     /gene="cmk"
                     /locus_tag="ACF3MF_000630"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HFE3926655.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(60386..61021)
                     /locus_tag="ACF3MF_000631"
     CDS             complement(60386..61021)
                     /locus_tag="ACF3MF_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HFE3926656.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(61087..62490)
                     /locus_tag="ACF3MF_000632"
     CDS             complement(61087..62490)
                     /locus_tag="ACF3MF_000632"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0043138 - 3'-5' DNA helicase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HFE3926657.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            complement(62477..63508)
                     /locus_tag="ACF3MF_000633"
     CDS             complement(62477..63508)
                     /locus_tag="ACF3MF_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3926658.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            63539..63760
                     /locus_tag="ACF3MF_000634"
     CDS             63539..63760
                     /locus_tag="ACF3MF_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HFE3926659.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(63925..64662)
                     /locus_tag="ACF3MF_000635"
     CDS             complement(63925..64662)
                     /locus_tag="ACF3MF_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HFE3926660.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
BASE COUNT        17826 a        13615 c        11073 g        22297 t
ORIGIN      
        1 tactcaggac aacaattaac aatcccaaca gaaggctctg cacaagcagc tgctgaacct
       61 caagcagccg ttcaagaagc accagtccaa gctgaacaac ctgttgtaca agaaacggtt
      121 caaacggaaa aacaagcagc gcctgttgct gaaacacaac ctgctcctgc tgtaacagaa
      181 actgctgcta ctccagcaag cacaagctct gcaaaagaat ggatcgcaca aaaagaatca
      241 agcggttctt acacagcaac gaacggacgt tacatcggac gttaccaatt agattcttct
      301 tacttaaatg gtgactactc tgctgcaaac caagaaagag tagcagaaca atatgttact
      361 tcacgttatg gttcttggga agcggcgaaa gcattctggg aagcaaacgg ttggtactaa
      421 gattcattta ttaatcaaac agtttacttt tatacaaaga aagccaaaaa gaggtgcgac
      481 actagttgtg tcacatctct tttttattta cctaatctaa tgaaacgttc caagttttga
      541 taagtatttt ttttaacttc ttcaactgat agctctttga tctcagcgat tgtctttaac
      601 tgttcttcaa gcagtgagac ataatctttt tctgaaaaaa tcccccctaa agcccactct
      661 gctgcatgta gtccatccgt ttcaataagt aagtggtcga ttgggactgc tttagctagt
      721 tgccagactg ctggattctt tttcaaatca agaccaatgc tgaaataaca gcctaaatca
      781 atatagtctt gttgatagtc caaagaagaa taccaatgga tcaaatagtg attagggtaa
      841 gcttggatat aatttaagat ctctttttcg catccttttg tgtgcagtac aacaggtttc
      901 tcatttatgg ctgcaaaagc aagctgtcgc tcaaatactt ttttttgtgt agtcatcggt
      961 acattcgtcc aaatattatc taaccctatt tcaccgatga tccttgcttt tttcaaaaaa
     1021 ggctcaactt gttcaaacgt atagctatct gctttccaag gatggatacc gtaacttaag
     1081 gcttgagtct tacttgctgc aagctgtctg ttttccttcc attcttctgg cgaatcacaa
     1141 ttgatgatcg tcaaaatcgt gtgttcctgc tgaaggagtg ctaaactctg actcccatct
     1201 aaatgacaat gagcatcact taacatctaa ttcacctgcc aataactgat aaatcgtttg
     1261 cttcaactct gattgctgca gtagccattc acgtgaccgt cgtttttcag gcacttgaat
     1321 ctcagcaatc acatgtgccg gacgggcgga aagcacaaga atcctgtctg ataaataaat
     1381 tgcttcttcg atatcatgcg tcacaagtaa agtagtccgc tttgcttttt taggcagctt
     1441 caacatccag tcttgcatct gccctctggt catagcatct aacgctccaa atggttcatc
     1501 aagaagcaag taagaagaag gattcatgat tgttcgtaac aaggccgttc gctgcttcat
     1561 cccgccagat aattgttccg gcaaaaaatg ttcatagccg tttaacccaa agatatccag
     1621 ataatccctt acttgttctt cattgattgt tagatgattg attttttgat ataacgtaac
     1681 gttttgatag acgctcagcc aaggaagtaa catatcttct tgcggcatat aactaaatgc
     1741 tgtatggaga ccagttactt tttgatcgtc tactttgatc gttccagaag tcataggctg
     1801 gactcctgtt aaagttttca gcaatgttga cttaccggct ccgcttggcg cgacaatcga
     1861 tgtaaaggta tctttaggga tagtgaaatg gatgtcttct aatattttca ggttttcaat
     1921 gactacattc aagtggctga tttggattga catatctatc actcctattt tataaactga
     1981 ttagtgaata gttcttgcga aggtacatct tgcttgatca atccgttttc ctgcataaaa
     2041 gctgtataat tgcgccaaac tttttcttcc atcaatcccc aattctcagg atcatccgta
     2101 taattttttg acaagaatgc ttgtgattct tctaaaaacg tccgatcatt ttcttttgca
     2161 tatttttgca acagtttagc actgtcattt ggatccttaa tagcttcctg atagcctttt
     2221 ttcgtggcat ccataaaaga ctgtaccaat tctggatcac ttttgatcag ttgatcattc
     2281 gtaataatta ccggagtata gtaatctaac cgttcatcta attctttcaa tgggatatag
     2341 tttagttcaa tacccgcttc ttttgctttg atcatatccc aaccttcaaa gtaccattgg
     2401 atatctgagg attttcctaa gctttctggc ccttctccat tgcttcctac cattgtcagt
     2461 tttgaaaagt ccccgccgtc tttttccatc acagctttta agacagcttc ttcacttgga
     2521 ctttgccaac ctgcatatgt ttttccttca aaatcttttg gtgaatggat gttactgtct
     2581 gatagggtgg cgaatccaga agtattatgt ttgatcactg tagcaattgc tttgactggt
     2641 atattctgtc catctgcgtg agcataagtg acatcttctt gataacttac accaaattgt
     2701 gctttgtccg cacctactag accaatactt gtcgaattat ctcctggttc gatgatttgg
     2761 acatttaaac cagcctcttt ataatagcct ttttcttttg ctaggtagat gccagtatga
     2821 ttagtattcg gtacataatc caaaacaagt gtcacttttt tcaaatcctt tatttcttgt
     2881 ttgctacttg tttcttttgc agtgccacaa gcggataaaa gcaacagtag cggtaataaa
     2941 agccataatt ttttcatttg atccccttct cttaaaaaat ataaagcata cgataatacc
     3001 cttttttcaa taatgaacaa gcgccattca gcaataaact caatagaatg acacaaatga
     3061 tcgcagcaaa aactttatcg atctggtagc tgttttttac gcgtatcatg taatacccta
     3121 agcctgcttg agcgcttagc cattctccaa cgactgctcc gctgacacaa taagtagcag
     3181 ccacttttaa accggaaaag aagccggata aacccgctgg tattttatat attcgataaa
     3241 tcttccctgt atctgccccc atcgttttca aaaagatgat ttgctctttt gatactttcc
     3301 tcaatgtatc cgaaaaagaa actacgatcg gaaaatagct tatcaagaca acaaggatca
     3361 cttttggaag cataccgaaa ccaaaccata gggtaagtaa tggccctaac accatgattg
     3421 gcaacatttg tgaaatcact agtaacggat aaaaagacat ttctaaaaac ttccaataat
     3481 ccattgccaa ggcagtaata aaagaaagaa cgctagctat taccaaacca agcactgctt
     3541 catttaatgt cgtgacagaa tgggaaagta atacttgtgc atctgccgct aatgcagaaa
     3601 atacagcagc aggtccgggt aaaataaagg caggtatttt ccaaactatg acaacaatct
     3661 gccaaataat taaaatgaat gccatactga ctgctggata aagatttttc ttcattttgt
     3721 tacctccttt cttctaatat gaataacaaa aaacgcttga aatgggcacg acatagtaac
     3781 ccgcttcaag cgtctgctat gtttctccct tcaccagtat taactgacag gttcaatggg
     3841 tctaagttca caacttactc tcatgtcgtc tacgacatcc ccagaaacag gtattcattt
     3901 tttaaagtgt agcacaagaa ggaaaaagca acaagcgctt tagttatcat gctgattatt
     3961 tcaataaata ggagagatca cttgccaatg tcggataccc catgatatag ctatccaact
     4021 cttttttagt caatttttga ttgatgacga gtgtcaaatc atcgatcaat tcgtctgctt
     4081 gctcgctaat cactgcagca ccaatcaaat aattttgctg gtcaaaggtc aattcagcct
     4141 tagcaactgg ttcattgaca cgatgatagg tgaaccaact ggtaagatcc atctctacca
     4201 cttgatctga cgaagaggcg tgactttttg taactcctac ttcagcaagt ttaggactgg
     4261 cgtagacgat cgtaggtata atcggatatt tgataggttc gcttgttgca tccgttatcc
     4321 gcttagctac ataatttcct tcaaaagtgg cgactggtgt caattttggg gttttccttg
     4381 aaacaatatc tccacacgca aaaatttttg gattgctcgt ttgcagataa tcattgactg
     4441 caattccgtg tttatcaaag acgatattcg cttgctcaag tgctaaagat tctgtattcg
     4501 gctgtctccc agtcgcacaa aaaatcatat ctgctactaa ttccgtctct tttccgacta
     4561 aacgatagcg agtaccttct gaaatgatct tttgggtttc aacaccaaaa gcaaactgaa
     4621 tgccagatgc ttccatttga tggacggctt cctctaccaa agacgcctca aattctttta
     4681 atggccgttg attatgatgg acaatggtta ctttgctccc tgcagcattg gcaatcgtag
     4741 ctagctcaaa agcaatataa ccaccaccga taaaaatgat ttctttaggc agtacaggca
     4801 atgataaaaa gtctgcacta gttttcaagt attcctttcc ctccactggt aagatcgtag
     4861 gtctttgccc ggttgccaaa actaagtaat ccgcatggaa gacttcttcg ttgacttcaa
     4921 tagatgaatc atccaaaaaa cgagcggttc ctgaaagatg atcgatttca gcttctgcta
     4981 attgtttttt tcggctttct gggactggat ccgtaaatgt tcgtttgaat ttttgaagtt
     5041 cttcccagtt ggcagttggg atctcgttaa aaccttttcc actcaattgt tttacccgat
     5101 tacgtgcctc tactgcactt aacaagactt ttttaggatc acatccacgg ttaggacaag
     5161 tcccgcccca tagatcttct tcgaccacta gtactgtttt acctgcttct ttcaatccat
     5221 aagcagcact taagccgctc acacctgaac cgatgatgat tgcatcatat gttttcattt
     5281 ccttcctcct ctcgacttaa aaaagcaaag atttctttac ttgtcagcga cccaatactt
     5341 ctttgctttt ctactatcac aatgcttgga tacaccgaaa gaagcgaata tacttctttc
     5401 ataggcgtat caaagcaaac ttgttgacga gcattttctg gtatttcatt taagaaatat
     5461 ccattgacga ctaaatcttc tactcgccac tctttcgtct gtttcggttc atcaaagaaa
     5521 tgccgaacgt agtcgttttt aggattcatc aataactgct ctggtgtgtc acattggata
     5581 atttctccat ccttcataaa tgcaatacga tcacctagct tgattgcttc ttccatattg
     5641 tgcgtaacga aaacgatggt cgtgcccaat tcttcgtgta aggacaaaac caattcttgt
     5701 aatgagtttc ttgaaatcgg atctaatgcg ctaaatggct cgtccatcaa aatcacatct
     5761 gggcttgcag caatagctcg gatgatcccg atccgttgct gttctcctcc agacaactct
     5821 ctaggcatac gatctcgata aatatcagga gataagccaa ctttttgaag aagttcatct
     5881 acacggtctg ctcttttctg cttttcccaa cctaacattt cagggatgac ttcaatattt
     5941 tgcttgactg tcatggtcgg gaacaaagcg atttgctgca gcacatatcc catattccac
     6001 cgcattttct gcagattata ttcatttaac gattttcctt tgaagtagat gtctcctgct
     6061 gatggtttag ataatccatt gatcattttc aaagtagttg tttttccact accggaagga
     6121 ccaaccaaaa caaagatttc tccttttttg attgccagat ttaggtcatc gatgacatac
     6181 tttccatcat actttttttg cacatgtttg aactcgatta atttagtcac tgatcttcct
     6241 cctttactaa tccttcattt ttcaggaaga ttcgtgctac ttctgtcggc tttttctttt
     6301 cgacattgac ttggtaattc atatcaatca tttgatcctc tgttattttt ccgcttaatt
     6361 tattcagtgc tttaacgatt tcaggatgtt ctttagcaaa atcttttttc atcagcggtg
     6421 cgccttgata agctgggaat aaccctcgat catcttctag agtcactaga tcgtactcct
     6481 tgagctggct atctgtggaa taggcatcca caatattgac atctccatta ttgattgctt
     6541 ggtaacgcaa acttggctcc atgctttgta cacttgaaaa attcaagcca tatgcttctt
     6601 ggattccttt atatccatct gaacgatcaa taaattccag tgtgaatccc gctttgatct
     6661 gatcagagat agctgccaaa tcggaaatct ttttaagttg atgttcgttc gcaaaagatc
     6721 tcttgactgc caaggcatac gtattttggt aagccattgg ttttaataat gtcatatcga
     6781 attgcttatt caataattct tctgcttcgt catatgtttt ttcttttgtc aaatcagcac
     6841 ttttcattgc ttcaggtacc ttcaccaagc tttctaggac agtacctgtg aactcaggat
     6901 agatatcgat ttgaccttga tccagtgcat tgaacaaaaa actcgtcttg ccaaaattcg
     6961 gttttaattc aacttctgtt tttgtgttgt cttcaatcaa ttctttatac atttggatca
     7021 ggatttcagg ttccgctcct aattttccag caatcgtgat ggtttcattt ttaaacaagg
     7081 cagactgata taaagaaacg ccgccaaata aacacaccac tgctgctaaa gtaatgatgg
     7141 aatatcgagg tttcttatgc tgcaaccagc gaatcagtcc gctgaatata attgcaagca
     7201 aggcagaact gatcgcacca atcaatgtca aaacaggtgt atttcggtca atacctaaca
     7261 aaataaatgt ccctaatcca cctgctccga tcaatgctgc caaagtagcc gtaccgatga
     7321 ttaaaactaa ggcagttcgg atacctgaga taatgacagg taatgcgatg ggaagctcta
     7381 ctttcagcaa gcgtctcatt ctggacatac caaatgctac cgctgcttct tcaatagacg
     7441 ggtcaatttc agctagacca atatacgtgt tttggaaaat cggaagcaaa gcgtaaataa
     7501 caagtgcaat caatgctgga acagttccga tccctacaaa tgggataagt aaacctaata
     7561 aggcaagtga aggaatcgtt tggagcacac ccgtgatctg caataagact tctgccattt
     7621 ttttatgatt ggctgcccaa atcgctaaag gaatagcaat cagtgctgca atcagcaaag
     7681 aaatgagaga aatggacaga tgttgaaatg cagcttccag caactcgcct tttctttcac
     7741 ttaatgtttg tataaaatta ttcatgcgac cttcctttct gttattcttt aagtataaac
     7801 atttctttcc tttttcccaa ctaacttgtc ttgccttaac cttacagcac gaacaaaaaa
     7861 aagaaaaaaa tacctctaaa tatgctgaca aaaaaagaat ccaagcaaca aagtcggatc
     7921 aactttttgg ttctcgtttt ttcactacga ataccataaa aatctatacg aaattgtcac
     7981 ttggaatcag ctatatcttt tttacacaca caacttttat tttaataaaa agaaacagcc
     8041 aataaagtag aaatctcgtg ggggagaaca cctttattgg cctgttcaac gaatattata
     8101 ctgtatcatg acactttttt gccaaaaatg taaaaaatgg ttgttttgac atcataaacg
     8161 tcttgttttc ttatttttac ttatatcacc actttatttt ctatctcttt cactccataa
     8221 agaggaatga gttcttcttt tgactgataa taaacagctt tctcacggtt cttcatcaaa
     8281 aaaagaaaga tgtctttcat agcaagtggt gctttgccgt gttcaaataa aaagataaat
     8341 tgatttgctt tatttatctg gaccattgtc acaggcacca gtttttgttc ttgagccaaa
     8401 aaaactcctt gatactctgt ttttttgggt gattttgtaa gaattgtcaa taagtctgct
     8461 gctcgcattt ttccactcct tatttgataa ataaaaagaa acagccaaaa ataatttttt
     8521 ttcattttcc tcttgaagta agagtataag tcagtataat aaagaagttg ctgaaaattt
     8581 tcaaaagaaa agaggctaga aatgaaaaaa ttaaatttat ttacagaatt gtgcggaatc
     8641 attttaggcg caggaatcta cggattagct gtgacaggaa tcaatattcc atctaagctg
     8701 gcagatggtg gggttactgg tattgctttg cttttgcata atctttttgg attcgctcct
     8761 tctgtcactt cactgctttt taatttacct ttattgctta tctcattgtt tctttttgga
     8821 aaacacgctt ttctccggac gatcgtcgga acatttgcgc tagttttctt tttacattta
     8881 tgggagagcc ttcatataca ttttgctgta gatagtctac tgatcaatag tttgatgaca
     8941 ggtattcttt ctggcattgg ttgcggtctc gtctttcgat tcggcggaag cacaggcgga
     9001 acagatatca tttatcaagc cattgaaaaa tattttcata ttaagattgg caaaagtctt
     9061 ttcttgatta cttttggtat tttagttgtc tccttgcttt atttggatct cacacatttt
     9121 ctgtatacat tacttagctg ttctattcta tcttatacat tgaataaagt gaagtatctg
     9181 gaaattggat ctgttttgcc ccaattggaa gcaaaacaga ctacagaaac atttgaacca
     9241 cttgatcctc ttgaacagtt agagcactga ttcttatttt tcactacttt atttaattta
     9301 cagaaatatc attatgtaaa ctaaaatgat attattcagt aaaatcttct ttataaaaaa
     9361 ataaactatt tttgcaaacg atctgcgaaa atagtttgtt tttttatttt gccattattt
     9421 tcttacttat tgggagaaaa aattcgctta aactcaaaaa aatttgagga tacgatataa
     9481 actttcggat agagtataaa ataaggaaac gccgcagcgt ttcctttcca actgtagccg
     9541 aatataaatt tgtatatcac ttatttaaaa tagctatttt ctcccaaaga gtttccttga
     9601 tcatcgatca atccttgtaa tgagcgttct aagataccat ggcttttttt cgattttttt
     9661 tcttctgact gctttgtttc ctctaacgtt tttgttcgat tgaatgttcg tacagacggc
     9721 tcaccatttc ttttttcttg atacggcgtc ggttctgtat cgaacaacag ataagagtca
     9781 tccgtttttt tcatcgattc gattaaatga tcctcagaaa ttttgctttc tctagggtct
     9841 gggataatcg atgcgggtac atatttagga acaaaataag aacgctcccg caccttcgtg
     9901 tcaacagatg cgtttcgtgt agtatgcttg gactctgtcc ttgtttcact ttgtctgaca
     9961 gaacgagagg aatcaccaaa aagttttttt cgtcctgtcg atgtgatttc tgattggtaa
    10021 tggccggtat aatccggtaa ttttccttta tgcttttcca aattttcctt acgcggagct
    10081 gacttcaatc catttgttgc acgacgcttg cgacggattt tctcggtgtt cgtgttcgtg
    10141 aaatgaaatt ctttcatctg ttcaaacggg gactgattct gttcagtcaa aagatcttct
    10201 tgtccgtcaa ataatactcg cttcttgtcg ttggttaatt ttacgcctaa ctcatcatcg
    10261 tacgcaggaa aacggaaatg ttttcgtctg atttctttca ttcaaaccat ccttctcaaa
    10321 aatggaactt ttctcaataa tagcacagat tcattgtttt cagtagcaat gcgctgatta
    10381 ttttaagaaa atagcgatga atttcataaa tatatatata gtaataagac ttaattcgtt
    10441 gtctctctga taactagttc aggaaaaaaa cgacgataac cttgactcgc ccctttttct
    10501 tctatttttt ttaacaacat ttctccacat acttcaccca tacgtataat atcttgcttg
    10561 atcgttgtca atttaggtga actgatttgg tctaaaaata ccccatcaaa tccaatcaca
    10621 ccaaattctt cgggcaagtg tcctccagca tttataatcc ctcttactgc tcctagtgct
    10681 agccgatctg aactacatac aaaacaagtt ttatctgtaa aatctgccca gttttctgtc
    10741 atatatcttt ctacttctgt cgaatgattt ggaaaccgca agattttact aggaagatca
    10801 acttccttca tcacagataa ataaccagtt tcccttgaaa tttcaaaagg ctcgtccact
    10861 tcgataccga tataaataat cgtttgataa tctctttcta aggcatattg cgttgctttt
    10921 gctgtaccat attcattatc gctgtctaca taatcatatc cttcagaatt ttccccaaac
    10981 aagacaactg gtttttccaa acggtcgatc caatcgaagt ctttttttct gacacctgtg
    11041 atgatgtatc catcacaaga accgacgtcg aaggcatcat ttgtaactaa ttggagagaa
    11101 taatgcgctt taccgatccg tttagcgatt cccatcagca aattcatgta atagggctca
    11161 gttgtgtcga tttcttccag tataaataat ttgatgatct gcgaccgatt cgtgacaagt
    11221 gcttttgcag caatatttgg acggtaatcc agttcagcca ttgctgagaa aactaactct
    11281 ttcaattcgt cagtcacctg ttccggatga ttgatgactc gagagaccgt catttttgaa
    11341 acattggcac gttttgcaac atctgctaaa gtgggcatgc tctcttcctt tctaacatgt
    11401 tgtcattctt actatcaatt ataccaaatt ttcctaacag agtttattat agcccaaaat
    11461 aaaaaacgga aaatcctcta tcgtcatgag tgattttccg tttcaattat ttatactttt
    11521 ttatcaaatt ttttgctaaa aaagtggaag cttcttccat tagtggtatt tgtaccatat
    11581 gtcgctgtgt ttttgaggaa cgaaaaacaa tttcttttcc gtaagactta tgccgatttt
    11641 tttctacaaa tcgttccgtt tgtatataag ggattttttc gtcagcttgt ccatgccaaa
    11701 agaacagagg acgtccagct aacttttccg gctgcaatga caaatcatag ctcttaaccc
    11761 atgaaatcaa atcaaaatag tcttttggta cgacataatt atattccgat gcgcgcctta
    11821 cgatttcttt tccatattcc aaaggtgcag gggaacccat caaacacacg cccgctacta
    11881 tatgaggatg tttagccaac aaggcgcatg ttgtcattcc ccccatcgaa accccgccaa
    11941 ctgcaagctg atcatgtaga agacctcttt tttctaaatg cttgataagt gtgtcaaatt
    12001 caaacagatt tccgtagata ctatcccaaa atgtatagga tggaatagaa gaaaccggct
    12061 gtttgcgctc cccatgattc atcgcatctg gcaggatcac acgaatgccc tgctgcgcaa
    12121 tttttcttcc ttgcgtcaaa actaactcct tacttgtctg ccatccgtga taatagatga
    12181 caacgggaat acgttcctct cttaattctt tcagaacaac ttctaacact ggaatatgat
    12241 ggacagaacg tttcaatata attggattca attgttactc acctattttc attaaatttc
    12301 ctgatcgcca tagcaaccat gctccaacag ttgtctggaa caggttcagt gtaccaaata
    12361 atataaatgc aggactgaat ggctcgggaa ataagcacag agaacaaagt cccaccactc
    12421 ctaatgctag cgaaaggagt ggataaatag aaaaattcaa aaaactggca acgctaccga
    12481 aaatattacc aataaacagt atcaaaaaga aaaaaacgct taaaattaaa ccatctgtca
    12541 gcgacatctg aaaaacaatg ttctctacct caattggctg ttgaatcgaa tagacaccta
    12601 agtatatact gagaaggaga cttagcacgt ggctggcaca aaacacacga ttgaccgttt
    12661 tcattttaat cacctaacct atctttataa ttctattata atcattttat catttttttg
    12721 tatgtataaa gtttcaattt ttcttcactt acgatttttt ttgatattgt tgttatataa
    12781 atgaaaggag ttttacaaat gattgatcca aaaatgttgg ggatgatctt cctcattaat
    12841 tttgcttata tcactctgaa cacgttacgt ttcatgttga caatgaaagg ctatcgactg
    12901 attgctccac ttgtcagtat ggtcgagatc acgatttata tcgtcggctt atcccttgtt
    12961 ttagatcgtt tagataatcc actgaattta tttgtctatg cgttaggtta cgcagtaggt
    13021 atcagtgtcg gaattttgat tgaagacaaa ttggcattag gatacatcat ggtcacaacg
    13081 attttgccag caaatagcgc agaagataaa agtttgccgg gtatactgag agaacacggt
    13141 tatggtgtga cacagacttc tgcaatgggg ctggaaggtg agcggctagt tctcgaaata
    13201 ctttctccta gaaaaagcga acgtgaactg tatcgcctga tcaaagaaat cgaagagcgt
    13261 gcttttatca tttcttatga gccaaaatat atttcaggtg gtttctggac taaaaaagtg
    13321 agaaaacgac aaggaaaata actcacaaac ttaaaaactg tctaatatct aaattaaatt
    13381 ttaaatgtta gacagttttt atttattatt ttgattaaaa aacatcgaca tatactcatc
    13441 aatttgttat tatactttat atacttatca atttaatttg gagatattat ggaaattcaa
    13501 cgtagaacca ctaatttttt acatttaggc tctttttttg caactttgac gatcttattt
    13561 tttctatgtt attcatacct taagacctca catgcgcctt ctagtgcatt aggctggttg
    13621 cttttggatc attctgatat cacagaagcc gaagaaaatc cgtttttttt gattttgtct
    13681 tctctttgcg gcttactgtt ttctgtttat ttcggtgcct atttttttca tcgacatcct
    13741 ggtacgttaa acgaagcttc aagcgtattg attgcattta aaacgttttc ttttttagca
    13801 attctttttt attcgtttaa tcacaatacg cttttcttct ttatcatgaa tggtttagtc
    13861 gtgattttat ccatttttac ttattttatt ttttcactca tttttagcca attgaaatgt
    13921 ccgctcttct ttcgattagt tcctgtcacc tgttttattt acagcttgtt ttcctttttt
    13981 gtccttgctt taatgccact gaccaaccct tcgacgatcc aagtcgcagg aaatctgttg
    14041 gatatgctct tcatcgtcag tctaggtgta tttatgtggc aaagaaaaaa caaacaaaat
    14101 aaaaagcatt ttgaagcctg actattacga cttcataaat gcttttttag ttttaaacac
    14161 ttcaatctaa aagaataacc caagattgga taaattatta atgactcgcc attcgtttct
    14221 tagtgattct ggattatcaa atggacttcc taatctaatc agctagttct tcccataaaa
    14281 tgccatactt gactgaatca taatattgat tatttaaaaa tctaactttt cttatcacta
    14341 cttcctttgt cattccacat ttctcaccat ttttttgcat tcctttgttt ccagaccatg
    14401 tagtgaatct aataggtggt agataggcaa aatactcaaa taattctttt aaccataaag
    14461 gaagagaaag gctcctcctg caagagtcag tataattttt gcttactgct ctcttaggtt
    14521 ttactcacta aaactgttcc atattctttg atataagaaa atgcatgcgg tataaatttc
    14581 ttgctcagct cagaaaagat ttgtcgttta agaaaggcca tttcctccat tgtcaatgaa
    14641 ggatccaatg ttggtaattc aatctcaaaa ttgttttttt cgacaatagg taattctaat
    14701 gtgaatgatt cttcttcctt tatagtattc gtcacaagta gagactgatg gaaaatacta
    14761 ggccggcgat ttttatattt attcttacgt atcctgtcaa cgataacttc tatttgatca
    14821 aaaaagtacg attcatttac gtctccaata agttcggcta attctttgaa tgccttcgtt
    14881 acaggaagct gattcttctg tacaaaaaag taattagcca aagtaagcgg gaagtgttct
    14941 atagaggaaa gtgtgataaa acggtacttc tcatttcctg cagttgtcct cagcaattct
    15001 gtctctcggc tgtttcttac tccataaaaa tacgcttctt tccgttcatc ttcgaaacaa
    15061 tacgcccaaa taacttctcc catcgctaat ttttgttcat caacagagag tctcttcaat
    15121 tgttcagcta tggtttcagc agccgaagtg gcttgttgca agtaatcttt aggatcaaat
    15181 attggaaagt tcaaatgata tcttcgttct tccctcttga ttaatcctgc atcgatcaat
    15241 aaatcaagaa aatgggaaaa tttattttgc gaaaattctt ttttcaattc tcttagaatc
    15301 gtttcttgtt ctcgatgttc atatagataa tcggtcaatg aagaaaaaag cggatcatcg
    15361 gtcagttttt gataaaagtt ttccttattt tttgaataat agttcatata tgttctcttt
    15421 tctatccgtt ttattttact taaaaggctt ttacgtaaaa aggaggaaga acaagagtca
    15481 taattgactg ttattctcct ccatttcttc ggcctttagt atgttctatg tttcttttta
    15541 tatcaatcgc ttatccattc attttgaatg cttcatacta ccatttgatt agctaaatac
    15601 agccgtcaat tgaggtacga cttgtttttt acgtgaaacg acacctttaa gcaaagcacg
    15661 gttgttggtc aaagttgttt ggaaagcttc ttctactttt tcttttcctt taccagcaac
    15721 aagtaattct gaatcactgt ctaagatgtt tgtgacaact aatacgaaca gatcgtagcc
    15781 atttgctttc atttcatctt ccattgctgc ttctagctct gcttgtcgat ccatcacttc
    15841 attaaggtcc actgtattga cttgagcgat acgaacgttg gaactgccca ttgggaaact
    15901 ttttgcatcc aaatcaagaa gaaccgcagc tgatttatca cttagatttg ttcctgcttt
    15961 caacatttca agtccataag tgtttagatc gacttcagcg attgctgcaa gttcttttgc
    16021 agctgcttca tcttcaggcg tacatgttgg tgatttgaac aacaatgtat ctgaaatgat
    16081 agctgagagc atgattcctg cgatttcttt aggaattgtt acttggtttt ctttatatag
    16141 ttttaaaata atcgtacttg tacatccaac tggttctgca cgatagtaca atggattagc
    16201 tgtttcaaag tttgcaatac gatggtggtc tactacagct aaaatattta cttcgctgat
    16261 atctgaaata ctttgttgga attcattatg atccacaagc atgacatctg cattttctgc
    16321 tttagctgac tctactactc gtggtgcaga tagctgaaag tggtctaatg cgtattgtgt
    16381 ttcttcatta ggtgtaccta gagcaactgc ttctgtttct ttacctaatt cattttgcaa
    16441 gtgtgaaaac gcaatggctg ccccgattgc atctgtatct ggattttggt gaccaaaaac
    16501 taaaattttt gacatgtcat tcgctccttt gtgatttctc ctatttaata atagcaaaaa
    16561 aacggaaaga agcaatactt atcttctttc cgatgcgacc tatcgcgtta aatattttgt
    16621 atactcttct gtatgaagca atcgtttagc attttcgaca cgttcttttg taggtggttc
    16681 gatcccttct aatggatatt tcaaaccaag tgtttcccac ttgtattttc ccatcgtatg
    16741 ataaggaaga atctctactc tgtctacatt tgacaaggtt tgaataaagt tgtctagtcg
    16801 gatcaaatat tcatcataat cacttcgctc aggaactagt acatggcgaa tccaaaccgg
    16861 tttgttgatt tttgacaaat attgagccat ttctaaaata ttttcattgt cccaatgcgt
    16921 tagtttttta tgctcttcat tatcgatgtg tttgatgtca aataacagta aatctgtata
    16981 cttcatcaat tcttgaaaac gtgaaaagaa aggttcttca tacgtaaaag gttttccgca
    17041 tgtatccaat gtagtatgca tcttccgctc ttttgctttt ttaaatagtt cgatcaaaaa
    17101 atcgatctgc aatagaggtt ctccaccact aacagtaata ccacctttat ctccccagta
    17161 aggtctgaag cgttctgctt tatctaaaag ttcatctgct gtgtattctt tccctccgcc
    17221 aatattccaa gtatctggat tgtgacaaaa ttggcaacgc atgcggcatc cttgcataaa
    17281 cacgacaaag cgcagtccag gtccgtctac tgaaccgaaa gtttcgatag aatgaacata
    17341 gccgattgtt ttttcttcca tttaagttca catcttttct ttgatttcat tttaagtaca
    17401 agttagctgt cgaagcgaag ctttctgaac aaaatttttc gcaattgccg cttcgttatg
    17461 tgtaaaattt acagggacgg aacatacaag tcctgcccct gtaaatcgtt tctttcaaat
    17521 aagcatactg attattcgat tttgatgcga tggctattca acgtcctttc gacgctaagt
    17581 cgaaaaactt ttttcacgaa ctttttacat tctgtcgtgt gaagttctca tcaagacatc
    17641 taattgttgt tctcttgtca agtcacggaa tttaactgca taaccagata cccggatcgt
    17701 caagttcgga tatttcattg gattttccat tgcatcacgc aataaatcat tactgaatac
    17761 attgacattc aaatgataag ctccttttga gaagtatcca tctaagacat tacgcaagtt
    17821 ttcgattctt gtatcttgtt cttttccaag acctgaagga ttgattgttt gggtatttga
    17881 aattccatcc aatgcacagc cgtaattcat tttagctgtt gagttcaggc tagctaataa
    17941 cccactttgt tccgcattgt aacttggatt tgctcctggc gcaagtggtt ttccagcttc
    18001 acggccatca ggagtatttc ctgtattttt accgtaaaca acatttgaag taatcgtcaa
    18061 taatgaagtt gttggttttg agttgcggta agttttatga cgtttgattt gtcccatgaa
    18121 gtattccaag atccatgaaa ctaattcatc tgcacggtca tcatcatttc cgtatttagg
    18181 gaagtcgcca tccacttcaa aatcaactgc tattcctttt tcattacgga ttgcttttac
    18241 ttttgcatat ttgatcgctg acaagctgtc tgccgcatga gagatcccag caatacctgt
    18301 agcaaatgtg cgttgcaagt cagaatccat caaagccagc tgagctgctt cataagaata
    18361 tttatcatgc atataatgaa tgatgttcaa cgtattgaca tatagttctg ctaaccaatc
    18421 catcatattc atgaagttat gtttcacttc ttcaaagtct agtatttctg atgtgattgg
    18481 acgatattct ggtccaactt gggcgccagt cacttcatcg actccgccat tgatggcata
    18541 taatagtgtt ttagccaagt tagcacgagc gccaaagaat tgcatgtctt ttccgacaac
    18601 tgttcctgat acacagcaag caatcgcaca atcatcagaa ccccattgtt cacgaagctg
    18661 attatcattt tcgaattgaa tcgaagaact ttcgatagcg attctgctag catatgttct
    18721 gaatccttct ggaaggtgtt cagaatacaa aacagtcaag tttggttctg gtgaaggtcc
    18781 catatttgtt aatgtatgaa gcagacggaa atcattcttt gtaactaatg aacgaccatc
    18841 taatcccata cctgcaatgg ataaagtagc ccagataggg aatcctgaga ataattggtt
    18901 atattcaggt gtacgcgcga atttgaccat acgtaatttc attactaagt ggtcgatcaa
    18961 ttcttgtgct tctttttctg tgattactcc attatccaaa tcacgttgga tatagatatc
    19021 aaggaatgct gagatacgtc cgattgacat cgcagcacca ttttgtgatt tgattgctgc
    19081 taaatatccg aagtatagcc attggacagc ttcttttgca tttgcagctg gtttagaaat
    19141 atcatagcca tatttcgcag ccatttcttt catttgcgct aatgcacgat attgttcagt
    19201 gatttcttca cgtaaacgaa tcacttcttc actcattgta tgataaccag tcatatcatg
    19261 atcttttttc ttttgttcca tcaaatagtc gattccatac aatgccacac gacgatagtc
    19321 accgatgata cgtccgcgac cgtaagcgtc tggaagccct gtaatgattt tgtttttacg
    19381 agcagcacgc atttcagcag tataagcgtc aaatacacct tgattatgtg ttttgcgcca
    19441 gtcagtgaaa atatgtgtca attcatcgtt tggtgtatag ccattgcttt ttagcgcatt
    19501 gttagccata ttgattccgc cgaacggcat gaatgcttgt ttcaaaggtt tgtctgtctg
    19561 tagaccgacg attttttcca aatctttatc caaatagcct gcatcgtgtg aagtaatagt
    19621 tgatacgatt tctgtgtcca tatcatagac accgttacgc tcgaattgga tatcatttaa
    19681 cttttgcaat tcatcccata atttttctgt tgcttctgtt gggccttcca aaaagctgtc
    19741 atcaccgcga tattcagtgt agttattttg aataaagtct ctagtgtcta cgccttcttt
    19801 ccatttggta cctttaaatc cattccattg ctccattgta tggacctcct aaatttctgt
    19861 tttatgtaac agtttttacg tgattagtat aacacagcac cctatctttg caagggtttt
    19921 cttgtttttt atttaacaat ttttatgttt tatttacata tatttaaatc aacgttgaca
    19981 taccaacatt taagcattgt gaacactttc atcttttttt gcaaacgtat aaggatttat
    20041 taaaaatgaa tgaaaaagag acgccacctg tattaataca gatggcgtct cttcattaaa
    20101 atactacaac agttacgact cgatgaaaat ctcaggagca tcgataactt cgatgacttc
    20161 tccacctttt ttctcatcca tcgcaaatga tccattcgat gttcgatcac ctatagggaa
    20221 atcagttggg tcaatcgtta actgctgccc tttttgattc atcaaggtta tttcttttga
    20281 tcttccttcc gacatataga taatacggtg cggatttttt ttcagctcac gcatgaccgt
    20341 cactccccgc ttcgcacgtg aagtttggct gatttcttga gcaagcatgc gtttaacagc
    20401 tcctcgctga gtaacgatta cgatcggcgt atcaccttct gctaacacaa gcagcccgtt
    20461 gataatccta tctccatctt tcaaattcat agacttcact ccagctgcct ttgctccaac
    20521 aacgggaaca tctgttaaag gatagcgcaa acccattcct tgatgcgtta ctaagaaaac
    20581 atctaagcct ggctgatctt ctttcagata cacagcaatc agttcatctt cttccgcctt
    20641 tagcttcata cagctgagcg gacggctctt ataggtgcgc catggttcga actctgtcat
    20701 tcgtgtttgc ttgatcaatc cattcttgct gatgaataca aatgttttct ctgcttgaat
    20761 tttttgatat gggaaaacag ctaaaatcga ttcgtctaca gacagattgg agattgtttg
    20821 agaaatgtgc tcaccagcat ctttccattt caaatcgggt agttcatgga cagggcggta
    20881 gatcacattt gctttatttg tgatcagaag aacatggtcc aatgtactca attcacctga
    20941 gtatagcaag tagtcgcctt ctcgcatccc gatttcttct ggtttggaag cactataaga
    21001 acgaaggctt gttcgcttca catagccttc tcgcgtcaca ctgacaatta cgtcttcttg
    21061 tgccactaag acttgcgtat caattttgat ttcttcgatt tcgtcttcga ttgtcgttag
    21121 acgagcggaa gaataatttt ttttcacttc tcgcaattct tttttcataa cagagaaaag
    21181 ctctttgtca tttgaaagga ttttattcaa ctctgtgatt tgcgcaatca agctttcgga
    21241 ttccttttga agctctgtga tatccgtgtt cgtcaaacgg tataattgca atgtgacaat
    21301 tgcttctgct tgttcttctg taaattgaaa gacgtcgact aaattctttt tggcgtcttt
    21361 tttgtcttta ctttcacgaa tcgttgcgat tacttcatcc agaatcgata aagctttcat
    21421 caatccttct acgatatgct gtcttttttg agctttggct aaatcgaatt gactacgttt
    21481 tgttatgact tgctttcgat gctcgatata acttcttaaa atgtctttca gtccaacttg
    21541 atgcggagtc atatggtcga tagcgaccat attgaaattg taattgatct gtagctcagt
    21601 gtttttgaac aaataattca aaattccttg agcattggcg tcttttttca attcgacgac
    21661 aatttgcaga cctgttctat cactttcatc tcgtacttca gctattccat cgattttctt
    21721 attcaaacgg atctcatcca tttttttcac caaggtcgct ttatttactt catatgggat
    21781 ttctgtgatc acgatttgct gtttattacc cttcattgcc tctatctttg ttttcgaacg
    21841 aagaataact tttcctcgtc ctgtttcata agcttttttg atttcatctt ttccttgcaa
    21901 gatccctcct gttggaaagt caggtccagg aatatattcc atcaattttt caaggctcgc
    21961 ttgtggatga tcgatcatat agattgtgcc atcgatcact tcagctaagt tatgagtcgg
    22021 gatttctgtt gcatatccag cagatatacc tgtcgatcca ttgacgagaa ggtttgggta
    22081 tcgagctgga aggactgttg gttctttttc tgtatcatca aaattccaca cgagatcgac
    22141 tgtttctttc tcgatatctg ctagcatctc tccacttaac ttggataatc tggcttcagt
    22201 ataacgcatc gcagcaggtg gatcaccgtc catactcccg ttattcccgt gcatttcgat
    22261 cagtacttcc cgcaacttcc agtcttggct catgcggacc atcgcttcat aaatactgat
    22321 gtcaccatga ggatgataat tccccatgat atttccgaca gattttgctg atttacggaa
    22381 tcctttgtca tacgtattgc catctttgtt catggcaaat aatatccggc gttgcactgg
    22441 cttcaatcca tcacggatat caggcagtgc acgttcttgg ataatatatt tggaataacg
    22501 tccgaagcgg tcacccatca cttcttctaa agttaattct tgtacttctt gtcgattttc
    22561 catcaggtga cctcctattc tacttcaaat aactgattgt tttcattttt atctgctcgt
    22621 tcttcatcta ataaatcatt agaaactgaa ggagagattt cagtatcctc ttttttatct
    22681 aagatactgc catcttcttc gagcgtaaat tgcacgtgat tttcgatcca ttttcttcga
    22741 ggttctactt tgtcacccat cagtgtggtt actcgacgtt cagcttgcgc agcatcatcg
    22801 atacggacgc ggatcaacgt acgggaagtc ggatccatcg ttgtttccca caattgttcc
    22861 gcattcatct ctccaagtcc tttatatcgc tgcagcatat atcctttgcc gactttttta
    22921 atcattgctg ccaattcgtc atctgtccac gcatattcaa tgacttgctt ctttccttgt
    22981 cctttggata ctttatataa aggcggtaac gcgatatata ctttcccagc ttcaatcagc
    23041 ggtttcatat aacgataaaa gaaagtaagc agtaatactt gaatatgggc gccgtctgta
    23101 tccgcatcgg tcatgatgat tactttgtcg taattacagt cttcgataga aaactcagga
    23161 ccgactcctg caccaatcgt atagatcatc gtattgattt cttcattttt caagatatct
    23221 tgcattttag ctttttcggt attgatgact tttcctcgta aaggtagaat tgcttggaac
    23281 tttctgtctc ttccttgttt agcagatccg ccagcagaat ccccttcgac taaatacaat
    23341 tcatttttct tagggtttcg ggattgtgcg ggtgtcaatt ttcctgaaag aagagattcg
    23401 ccttttttac gcttcttccc atttcggctt tcttctctgg ctttacgtgc tgcttctctc
    23461 gcttctctgg ctttgattgc tttacggacc aacatctggc tcatttcgct attttcctgc
    23521 aaataaaagc ccatttgttc actgatgacg ttatctacta cggtacgagc aactggcgta
    23581 ccaagttttt cttttgtttg cccttcaaat tgcagaagat tttcaggtac acggatagaa
    23641 agtacagcag ctaacccttc tctgaaatca ctaccttcca gattcttgtc ccgttctttc
    23701 agcaaaccaa cttttctcgc atattcatta taagatttcg tcatcgccgc tttcatacca
    23761 gcttcatggg ttcccccatc ttttgtccga acgttattga caaaagataa aacattttct
    23821 gaataaccgt cattgtattg ataagcgacc tctacttcga taccttcttt ttctcctgaa
    23881 aaataaacaa ctggtgtcaa tgtatctttt tcttcattca gataatcaac aaattctttg
    23941 attccttctt cgtaatgaaa aatttccttg actggttctt ctccacgaag atcagaaaga
    24001 gagattttaa cgccttttag aagaaaggca gattctctta accgttcggc taaaatttca
    24061 tatgaaaatt tcgttgtact gaatattgta tcatctggta aaaaatggac agtcgtcccg
    24121 tttgcttttt ttgtttttcc tatctttttc aaagtaccgt caggtttacc gccgttttta
    24181 aatttctgct gatactctac gccatctcta acgatcgtta caattagcca tttcgataag
    24241 gcatttacca cactggctcc tacaccgtgc agtccaccag aagttttgta ccctccttga
    24301 ccaaactttc cgccagcatg cagcacagta aaaatcactt caactgttgg tattccggaa
    24361 gcatgcattc ctacaggcat cccacgtccg ctatctgcaa cagttatact attgtcttca
    24421 tggatggtca catcaatctc actgccataa cctgataatg cttcgtcaac tgcattatcg
    24481 acgatttcat agactaaatg atgcaagcct cggctgtcag tggatccaat gtacatccct
    24541 ggtctttttc taactgcctc taatccttcc aatacttgga tggacgagtc attgtattcg
    24601 ttgtttactt tttttgccaa ggcaaacgct ccttcaataa tactttgcgg caaaaccgca
    24661 ccacgattat catactagaa aaggtcgtga aaaaaaagag ggtagacgag aaatcaattt
    24721 taattatctc ctaaccgctt tttcgacatt cccctctatc gatcatctct tctttgtggt
    24781 catttttatt tttggttttc tttcaactta ccaagttcaa tcttaataca acgatccatt
    24841 acgatatctg tacgtcctgc ttttcttagc atctcagctg cttctttgtt ttcaatccct
    24901 aattgtgccc agaacacttt agcatcagtt ttcaaaaaat cacctgctat ttcaggtaaa
    24961 aattcactcc gtctaaatac atctacgata tcgattggat catcgatttc tgtcaaattc
    25021 gcatagactt tctcgcctag aatttcttca ccagccaata atggatttac tggtatgatt
    25081 ttatatccat tgtcttgcaa tacctgtgca accatgtaac ttgttcgttc tggtttattg
    25141 ctcaagccta cgacggcaat attttttgct tcttccaaat agttgaaaat cgtttcttgt
    25201 gttggatttt ttacagacat ttctgccacc ccttgctttt ctttttattc catctattat
    25261 acttgtatct ttcatttttt caattgttcc tgttacctat tcatgctaaa ataaaggata
    25321 gttttcaact tgaaagaggg taaaaaatga aattgatctt attacttatt ttagcatatc
    25381 ttttaggttc tattccttcc ggtgtctgga ttggcaaatt gtttttcaaa aaagatatcc
    25441 gacaacacgg gagcggtaat actggaacga ccaatacatt tcgtgtatta ggcaaaacag
    25501 ccgggattgt tgtcctgctt atggatattt taaaaggtac attggctact tgtttgccga
    25561 tgatcttcca cctttctggg attaaccctc tttggtttgg ggtatgcgcc attcttggcc
    25621 atacatttcc gatttttgct gggttcaaag gaggaaaagc tgttgcgaca agtgcaggaa
    25681 tgcttttagg atttaatcct gtattttttg tttattcttg tatcatcttt atcgttagtt
    25741 tattttgtac aagtatggtg agtttgagca gtatgatcag tgcagtattg atcactttat
    25801 ctacgatcgt ccttccttat gtagctcctg tgattttggc taagcccaat tggttactga
    25861 cgatcattgc ctttttagtt tcttccttta tcttttatcg gcataaagac aatatcaagc
    25921 gtatcagaaa ccatactgaa agtcgaatcc cgtttggttt gaatagcagc aagaaaaaat
    25981 cctgatactt tttcattcca aagagataaa acgggagtgt gacaaatcga tgtcacactc
    26041 ccttattact tacaggatag cttttttaca caccttggta aacggtgttc cctgctaact
    26101 tctcggtcac aacctcttac ttcactgtga tggaatattt tgtcttgaag atttcatggg
    26161 cacctagttg attgatccct actttttcca tcaagtttcc actactgttc accgtgtcag
    26221 cgattccgca ccacggttcg atacaaacga aaggcgcttc ttttggataa ggagaccaga
    26281 tccctacata aggcatatct ttatagctta aagttacgct atgggaagat ttttcacttc
    26341 gaatggcgta cgcatttaga ccccttgttt caaaaaccaa ggcatcttgc tcaaaaagtt
    26401 cacgattcaa agccagattc gtatttgtct gacctaacgt cttttgatcc atatcgatga
    26461 atgggccttt caatggtagg cgtaatcttg atttcaatgg agaaaatgcc agatagaaat
    26521 cttcaaatga caatccttct tcaagaggta cattgaaagc aggatgtcca ccgatagaaa
    26581 agaacatttc tttttcaccg gtatttgcca cttgataatg aaccgtgatg ccgtctcctc
    26641 ctaattcata gctgatcact aattcaaaat caaatggata cttttctaat gtctccggcg
    26701 tactccttaa gatgaaacta gccatttctt gtccatgttc aatgacttca aaatccatat
    26761 cccgagcaaa tccgtgttgc cccatttgat atgttttccc ttgataaaca tactgatcat
    26821 cttttaaacg tccaacaaaa gggaataaaa ccggtgcatg tctgccccaa tacgctggat
    26881 caccttgcca gatatactct aaaccatgtt cttttgattt cagactgatc aattccgcac
    26941 cgtgttcagc gatttcggcg atcagctggt cattttgaat aataacagtc attgccattc
    27001 ctccaacttc gacttacttt ttaaaatggg aaggctggaa caaacatttc tatctgcccc
    27061 agtcccctta cttctaataa ctgtgttttg ctaactcgtc tttaaaacgg gaattcaata
    27121 cttttaaata agttcccttc atgcctaacg aacgagattc aatgattcca gctgattcca
    27181 attttcgtaa agcattgacg atcacagaac gagtgatgcc gatactatcg gcaatattag
    27241 aagcagtcag acgaccttca tctccatcca atgcttcaaa gatagcttgt acagccttca
    27301 attcgctata agataatgtg ttgattgcca tttggacagc cgttgcactc cgtacatctg
    27361 cttcgatgct tcgagacttc tgataaagga tctgcatacc gacaaccgta gctccatatt
    27421 ctgctaagac tagatcgtca tctgcaaacg attgttccat acgagataag ataatcgtac
    27481 ccaaacgttc gccagctcca aagatcggaa cgacagtcgt cagaccaaat ggatatttct
    27541 ctcttgactc taccggaaat gcagtaatat cactagtaat tgggatatta gcttcagttt
    27601 tcatcaactg tgccactgta tcagtataag attcaggaaa ttgtttctca acaaacattg
    27661 ttttgattcg ttcattgttc acatcgtgac gttcattata acctagtaat actccgtcac
    27721 ttcctatgat ataggtgttg ctgtcaagaa taccacctag tgtgacagcc attttatcgt
    27781 aaggcaaatc tgcttgcatg tcaaaagtat tcttttgctg caaaagtgtg tttatcttgc
    27841 gggttttcgt tagcaagtct gtcattgtcg tcctccgatt ttttataaaa tatagcgact
    27901 taaatcttca tttgccgcaa ttgagccaag tttgtcatcc acatatgctt ctgtgatcgt
    27961 tatttctccc atttgcatat ctggtgcttc aaataataga tcttctagta gtttttccaa
    28021 aatggtatgc agtctgcgtg cgccgatatt atctgtgtca cggttgacat cgaaagcgat
    28081 ttgagcgatc cgttcaattg cttcttttgt aaacgtaact gacacatttt ctgtaccgat
    28141 caacgcgacg tattgtttta ctaaagcatt atttggttcg gtcagaatct tcacaaaatc
    28201 ttcagctgtc aaatcatcta attctacccg tatcgggaag cgtccttgaa gttctggaat
    28261 tagatcactt ggtttagaca aatggaaagc tcctgaagca atgaatagga cgtgatctgt
    28321 ttggatgatc ccgtattttg tgtttacttg tgaaccttcg acaattggca atatgtctct
    28381 ttggacgcct tctctggata cttctccaga ttgctgtgat ttagaagtga tcttatcgat
    28441 ttcatcgata aaaataattc cactttcttc cgctaatttg attgcctcac tatggatatc
    28501 agcatccttg actaattttg ctgattcttc cttgatcaat aactctaaag cttctttgac
    28561 tgttaccgtc cgttccactt ttttcttcgg tgtcaaagca cctagagttt catttaggtc
    28621 gatccccatt tgctccaatc cattgttcat cattggtgca ggtttctttt ggtcttcaac
    28681 ttcaatggtt acttcacgac tatccagtaa acccttttgt agttgttcca agactgtacg
    28741 gcgattgatt cgaatatctt ctgtcacttc ttcttgcggt tcagcggtat tttgctgact
    28801 agcattaaaa agattcatca tttgttcaaa ttgattagtg gattgtttct gttctttttt
    28861 gataccaggt accaagattt ttaccaaacg tttttctgca ttttttttag cacttgtgta
    28921 tacacggctg tactgctctt tttctacgat ttggatcgca ttttctacta aatcccgaac
    28981 cattgattct acatctcttc cgacataacc gacttcagta aattttgttg cttcgacttt
    29041 gacaaatggt gcattgacga tttttgccaa acgtcgtgcg atttctgttt taccgacccc
    29101 tgtaggtccg atcatcagca tattttttgg tgtaatatct tgttgcattt tttcatctaa
    29161 ctgcaaacgg cgatagcggt tacgcaaagc aacggcaaca gatttttttg ctgcgtgctg
    29221 tcctacgata tattcatcta attcacttac gatttgtctt ggtgtttgtt ttaattcata
    29281 catatctact cacctcttac agttcttcta cgataatatt atgattagta aagatacaga
    29341 tatctgcggc aatatttaac gcattttctg caatttcttt cgcactcatg tcgttttgag
    29401 catagttttt cattgctcgg gctgcagcca acgcaaaatt ccctcctgat ccgatagcta
    29461 agataccatc atctggtgtg ataacttctc ctgtacctga aacaagaagc atttctttat
    29521 cattcattac gatcagcatc gcttcaagtt tttgcataga ttgctgtgtc cgccattctt
    29581 gagctaattc gacagctgcg cgttgtagat tcccgttata ttcgtttagt ttgccttcaa
    29641 atttttcttc taaagtaaac gcatctgcaa cacttccggc gaaacctaca acaacttctc
    29701 cattgtagat acgtcgtact ttctttgcag tgcctttcat gacaacagat tcacccattg
    29761 ttacttggcc atctccagcc atagcaaatt tcccgtcttt ttcgacggca cagatagtgg
    29821 ttgaatgaaa tggtgattcg accatgtttg tttcctccta aatttgttct tttccttatt
    29881 tttacgctct tggatggaaa gaacgatagt ttttttgtaa actttctttt gttacatggg
    29941 catagatctg ggtagtcgat aaattggcat gtcctagcaa ttcttggact gtccgcaaat
    30001 ctgccccatt atttaataaa tgagtagcaa atgtatggcg cagcatgtga ggatggatat
    30061 cactatccaa actgcttttt ttgatcattt gattcaagac atattcaatt ccagtaggcg
    30121 tgattggttt tccatgatga ttcacaaaaa cgatatcatg ctcttcgtga tattttgtca
    30181 tcaatacctg gcggccttcc ctgaaatatt cttgcagagc atcttgagca aaagaaccta
    30241 gaggagcata tctctctttg ttccctttac catggatcaa catgacctct gaatcaaaat
    30301 caatgtctga taccgacaaa ctgctacact cacttaaacg gatgcctgac ccgtaaagga
    30361 cttccagtaa agcgcggttc ctcaaatcca aaggactatc tcctgctacg ctgtcaaaaa
    30421 gtgcttgcat ttcattttca taaaaaaaac gtggcagtct caaatttttc tttttgagat
    30481 gaacgtaaga aaatggattt tcttttatca cttcttcttt gagaagatac tgataaaacg
    30541 aacgtaggct ggctatcttg cgactgatag aatttctgct atagctagga cgatgatcag
    30601 ctaatgcact caaatagaca cgaaccgtaa aatattccgc cttcagcaga tcagcgtctc
    30661 cagattcctc caaaaaatgt ttgaaatgga gaatgtcttc ttcatatgct tctttcgttt
    30721 tttctgaata tcctctttcg acaatcaaat aacgcaaaaa tttttgttcc cacgtggctt
    30781 ctgtcatttt ctcaccttcc ttttgtccca gagaataatt tagcacagcg tttataaaaa
    30841 gacaaataaa ttgtcagaat ttaaccaata tttctaagtt tgttcacaat tggcgcaatt
    30901 cctcacattt tgtttgagaa attcttaaga aaaacgcaag aaaaagagcg agactatccg
    30961 tctcaccctc ttcatggagt ttccttactc atttgggatt gcagtttttt ctaattctgt
    31021 ttttattgcc tcattagctt ttaaagctcg ttgtgcaatt gcttcatatc ttgctttttt
    31081 gtctcgaatg cgctctggca gttcaggaaa cagaccatag ttggcattca tcggttggaa
    31141 atgttttcct tccgcatgag taatgtagta agccatactt ccaatagctg tttcttgtgg
    31201 aaactcgact ggttccattt cttttgctaa gcgtgcggcg ttgattccag caagtagtcc
    31261 gctcgctgca ctttcaacat agccttctac accagtcatc tgacctgcaa agaacagatc
    31321 ttcgcgtttc gttgattggt aagtcggttt cagcaattct ggcgaattca taaagctgtt
    31381 tcggtgcatc acaccatagc gaacgaattc agcattttct aacccaggaa tcatccggaa
    31441 aacacgtttt tgctcgcccc atttcaagtg agtctgaaag cccacgatgt tgtataaaga
    31501 agctgcagca ttgtcttgac gcagctggat aacagcataa ggacgtttgc cagttttagg
    31561 atcttccaat ccaactggtt tcataggtcc gaaaagcatc gttttgaatc ctcgctgtgc
    31621 cattacttca attggcatac atccttcaaa atatttttct ttctcaaaag atttaagttc
    31681 tgccacttcg gcattgatta gtgcctcatg gaaagctttg aattcctctt ctgtcatcgg
    31741 acagttcaag taagctgctt ctcctttgtc atagcgggac ttcaaatata ctttatccat
    31801 atcgatcgta gctttgtcta cgattggtgc agctgcatca tagaaataaa aaccatctga
    31861 accattgaat gctttgatgc tttctgctaa tggatgagaa gtcaaaggtc ctgttgctac
    31921 tacggtgatt ccttccggta tttcagtaat ttcttcgttt atcactgtta ctaatggatg
    31981 ctctttgact tttcgggtaa ttgtttcaga aaaagaatcg cggtcaacag ctaaggcacc
    32041 accagctggc actgctgttt catctgccga agtgattact accgaattca atcggcgcat
    32101 ttcttctttc aataacccta ctgcattagc caaactgttt cctcttaatg aattggaaca
    32161 tactagttca gcaaaattac ttgtgtgatg cgcctcagtc gatttgactg gacgcatttc
    32221 atataaacgg acagggactc ctgcttgtgc gatctgccaa gcagcttcac ttccggcaag
    32281 ccctgctcca acaacattta ccattttcaa tgaaagaacc tcttttctat tatttttgga
    32341 tgtcttcttc gtaatctcca tttacacaga ctacttgttt accgcctttg actttcttct
    32401 cgaccagata tccgtcacat tttggacaat ttctgcccac tggtttatcc caagaagtga
    32461 attcacattc tgggaaacgg gaacaaccat agaatagtct gtttttctta gattttcgtt
    32521 caatgacttg tccttcatga catactgggc aagtcacacc gatttctttt acgattggtt
    32581 tcgtattccg acaatcagga aaattactgc aagcataaaa cttcccatat ttccctaatt
    32641 ttatcaccat cggatgtcca cagacatcac aatcgaatcc tgctggttca tctttgattt
    32701 gaattttttc gattttttct tccgcattcg tcagttcttt ttcaaacggt ttatagaaac
    32761 gatcaaccac tttgacccac gcttccgtgc cttcttcaat tttatccaaa tctccttcca
    32821 tttctgctgt gaaatggata tcgacgattt gagggaagaa ttcacagatt aatgaattga
    32881 caatttctcc tagttcagtc ggctcaaatc ttttttgtgt caattttaca tagtagcgtc
    32941 tttggatcgt atcaagtgtt ggtgcataag tggaaggtcg ccctaccccg ttttcttcta
    33001 gtgcacgaat caacgtagcc tcactaaaac gtgctggtgg ttgagtaaaa tgttgttttg
    33061 gttcaatatc aacagattgg actacatcgc cttcttcaag ttctggaaga atattttctt
    33121 tctcttcttt gccgtcatct ctaccttcca catacacttg catgaatcct ttgaatttga
    33181 tttttgaacc gttcgcaatg aagatgacac cattttgttc taatgtcact ttcattgtat
    33241 ctaaaatagc tggtgtcatc tgactagcca caaaacgtga ccagatcaat gtataaagtt
    33301 tcaattgatc tttatctaaa tattgtttga gttcatctgg tgtacgaagc acactcgttg
    33361 gacgcacagc ttcatgggca tcttgtgcgc cttgagcatt tttgatcttt cggtgatcat
    33421 gtctagaaaa ttcttttcca tacgtatctt caataaatgc tgcggcctct gcttttgctg
    33481 tatcggcaat ccgggtagaa tcagtacgca tgtatgtaat caagccgact gttccttgtt
    33541 tacccaaagt gattccttca tataattgct gtgctaccat catggttttt cttgttcgaa
    33601 agtttaactt acgggcagct tcttgttgca ggctacttgt agtgaaagga ttcgcagggt
    33661 ttcttttgcg ctctttcttt tctacttttt taacttcgaa gtctgttcca tcaattctag
    33721 cagtgacttc ttttacactt tgtgcatctg gtaatttctt tttcttaccg tcgattcccc
    33781 agaaatttgc tttgaatttc ttgcgagctt ttttaaaatt accgtcgatg ctccaatatt
    33841 cttctggaac aaattctcgg atctcttttt cacggtcaat aataattttt aaagcgacag
    33901 attggacacg tcctgcactt aaccctttct tgaccttacg ccagagaata ggactgatcg
    33961 aataaccaac gattctgtct aaggtacgac gagcttgctg tgcatctact aaatctacat
    34021 cgatcgttct tggttcctta aaagctgctt tgactgcgtc ttttgtgatt tcattgaaga
    34081 ccacccgatt tttttctttc agatccaacc caagtaggta cgctaaatgc caagcaatcg
    34141 cttctccttc tctatccggg tcacttgcca agtaaacttt ttgagctttt tttgctgcgg
    34201 ctttcaggct tttgatgaca tcgccttttc cgcgtataga aatataatgg ggttcataat
    34261 tgttttcaaa atcgataccc attttacttt tcggtaaatc tcttatatgg ccaacactgg
    34321 ccattacttt atagtttcgt ccaagatatt tctcaattgt cttggctttt gcaggtgatt
    34381 ctacaatcac taaatattta tacgccatta ctgaatggac tcctttccat tgtcgtgttc
    34441 ctactattaa aagaggattc atacaaatcg tagctaatca tatccattca gaaaacgttt
    34501 gtcaagaaaa gcaaatgaaa agtatggtgt tattctttaa attctgccaa gatatcttca
    34561 cccgaaaccg tgcaaactgc accgtcttgg atcaaatgat gacatccggt agaatgttct
    34621 gttaaaatat ttcctggaac agaaaaaact gttcttccaa gatccaatgc ttgctgtgct
    34681 gttatcagag agccgctttt tttcttggct tcaaagacac atgttccttt agacaaagct
    34741 gcgataatcc gatttctcat tggaaaacaa tgctttttcg ggccggattg aggaggatat
    34801 tcactcaaaa gaagatgatc atttgcaatc acctcttgca agtcacgatt ttcagcagga
    34861 tagacttgct ctatccctgt tccaatgact gcgattgtcc gtccaccatg agagattgct
    34921 gcttggtgac cgtatgtatc tatccctttc gcgcagccac tgacgatcac atatccagct
    34981 tctatcactg gttttagtaa ataataaact gtttttttgg ctaaagcaga agtgtgtctt
    35041 ccaccaacaa cgcttaacat gttacaagaa agtaaagata gatcaccatt ataaaacagt
    35101 acaattggcg gataggtcaa gtgaagcagc tgagggggat atttgggatc aaagcaagtg
    35161 ataaacgact gtttcgattg gattttgccc cagttagcgt gaatttcctg ccaacttttg
    35221 cgaaacagct cccggtgttt ggttatttta cctatcttaa tgatgtcttc aaatccgatt
    35281 tctttataag gatactgcat catccagtta gcaagtgccc attttccttg actactgatt
    35341 ccttttgtat aagcaagttt caataaattt tcttctattt gatacatcat aaaaccgcct
    35401 ttcgtctctc tttctaataa gatacgtaaa agcggctgtt ttttattgta aatatttttt
    35461 tacaggtgca aaacttttac gatggattgg cgtaattcct tgtcgttcaa gtccttctaa
    35521 gtgttccttt gttccataac ctgcattatg cgagaaacca tatccaggat aaagcacgtc
    35581 atattctttc atcaattggt ctcgatatac tttagcaatg atacttgcag cagcaatcga
    35641 cacagatcgt gcatcccctt tgattatttt ttcctgctga ataggcaaat ccaaggtcat
    35701 cgcatcgatc aacaaatagc ttggtacaat ggacaatttt tctactgctt ggatcatcgc
    35761 taatttactt gcttcataaa tattcacatc atcgattgtc tgctgatcaa cgatcccgat
    35821 cccgattgcc agggcttttt cttgaacttg ttgataaaga agttctcgct ttttctctga
    35881 taattgtttg gagtcattca gccctaatat gatctcattt ttcggcaaga taactgcagc
    35941 tgccacgaca ggtccagcta atggtcctct tcctacttca tcaatgccgg caatccattg
    36001 gtgaccttgt gcgtaccctt gcttttcaaa gcaaaacatt tcttcatatt tttccttaat
    36061 taatgcttcc tttttcaatc gtcgttcaaa agaagccagt gcttgctgca cgcctttgcg
    36121 tggatcattt cttaatgatt ctagtgtagg atcatctatt ctctgtatgc ttttcaatcg
    36181 ttctttgata ctttggatgg attcagtcat cacttttttg ctccatttct tcgcaacgat
    36241 ccagtgtgta tcgtccaagt tttccttgac gaatatcatg cacgactaat tcgctgccac
    36301 gatcatagtc ttctttatac ccacgttttg ctgtaatatc catcagtaat tccggtgcca
    36361 atttttcttc ttgctcgatt gataaaccat aacgatcgct gattcttcct gaataatatc
    36421 gggcaaaaaa gtctaatccg taaatcgcta aatcatctaa atggacaagc tggtctttga
    36481 tcgcgcctgt cagcgctagt tttttgccga tttcttcatc ttcaaatttg ggccataaaa
    36541 tccctggtgt gtctaacaat tccaactcat tacctaaacg aagccactgc tgaccttttg
    36601 ttacgccagg cttatttcct gtctgtgcaa ttttcttgcc tactagtcga ttcatcaacg
    36661 tagatttccc aacatttgga atacctaaga ccattgcccg aatagcgcga ggcttgatcc
    36721 cccgagcagc atctcttgcc cgtttttctt tcaatgcttc tttagccgca ggtactagac
    36781 ctttaattcc tttactttct tgtgccgtga tagctaatgc aagatggcct tgtttacgaa
    36841 aatattcttg ccacagcttt gtctgttgtg gatctgccag atccgcttta ttcaataaaa
    36901 caaggcgagg tttttgctga atgatctgat ctagcattgg attacgagaa gataaaggta
    36961 atcgtgcgtc taccaattca aatacgatgt ccacatattt cattttttca gaaacttctc
    37021 gtcgggcttt tgccatatgt cccggaaacc attggatggt cattgttctc tccattcctt
    37081 tcataccgga atattccccg gctttacttg tttttttctt tttcaatata aattcacttt
    37141 tttattataa agaaattcca tctattagtt aagtgaaagt gaaccagtcc tcattctatc
    37201 acatcttcac ttttttgatg atgcaaattt ttattttggt ttctatatat gaatctaaat
    37261 ttttgacagc gtttcctaaa taagagatga tagacgaaca aaacagaaag gagacgaaac
    37321 aaatgaatag tatggttttt gttaattttc ctgttgctga tgtcaatcgt tccgttgctt
    37381 tttatgaaaa gctgggtttt aaaaaaaatg aagaattttc tactgaagaa gctggttcaa
    37441 tggtatggga tgacactttt tggataatgc ttctctctca tgatttttat aaaaaattta
    37501 taaaagataa agaaatagct gataataaaa aaacaagtgg tgctttgatt tcgtttagtg
    37561 ttgaaaatgc ggatgaagta aaaaaatttg ctcaaattgc aaaagaaaat ggtggtactt
    37621 tccacgaagt agatatggga atgcctgaag aagaaatgtt ttcattagaa gtccaagatc
    37681 tagacggaaa tacattagaa cccgtatgga tgaagatgta agcagataac taatctgacg
    37741 ttttttataa caaaaaaaca aaggcggatg atacgataag tattctccgc ctctattttt
    37801 tttattcgta caatctcttt tttacagttt ataaaagcag tcttctcacc ctttttttaa
    37861 ttgttagatg ccagtgtatg taaatcacca atgtgtcatg acacattggt gattttatgg
    37921 tatcctttta ttattaactg acaaaggaga gaatattttg aacactttga ttgcaaaaga
    37981 cgtttttaga ttgcccgaaa tgaatgcaag attgttgtcg acctctgctc ttttattagc
    38041 ccttgatgtc atcttataca agatagcgat tggtcctgct tattttcaaa tcacattcgg
    38101 atttttaagt atggcgctta tgggttatct atatggaccg atctgggctg gtttgcttga
    38161 aatgttgtcg aacactttaa atttcacgat atttggttca ggaacgtttc aagctgcttt
    38221 tcttatcacg gctttccttg gtggatttat taatggctta tttttatatc ataaaaagat
    38281 aaacctgcct tccgtcatcg ctgcccaatt attgattatg atcccagtca gcctttttat
    38341 caattcttgg ctgatgtctg ttttgtttgg tgcagatttc aaagtaattt ttctaggtag
    38401 attcatcagg aatatgatcc aaatccctat tcaaataatg gttgtttatt catttatcaa
    38461 aactttagag gctagaaaag tgtttaaacg agctgtttga ttttacgtac taaggtagta
    38521 aactgatttt ggattaaaca ataaagcgtg cagtctcaac agactgcacg ctttattgtt
    38581 tctcactgga tccattttat ttcatcaagt ggataataga caaatcttgc tttacctaga
    38641 atatcagttt tattgatcgt gccaaacgaa cgactatctt ttgaaactct tcgattatct
    38701 ccaagtacaa aataattatc ttccggaagc ttggattgtc ccgttagctc ttgtagtgta
    38761 aagtccgtcg tataggatgc atttgcatga tctgatttca ggtttttagt tagataaggt
    38821 tccttaacta ctttcccatt gatcttcaat tgatcatttt ggtagctgac attttctcct
    38881 ggaagaccga ttactcgttt gatataaatc gtgccatctg ctaattgaaa aacaacaata
    38941 tcaaatcgtc tgatctccga aaatttttcc atcacaacca tatcaccttg cttcaacacg
    39001 ttttccattg aattgccttc cactggtacc gggatgaata aaaatccccg caacatgaac
    39061 gcaaggaata cagaaacaag taagtatttg aatacaagcc agaagcgatt aatatagcgt
    39121 tgtttttttg tcaatctcta tcaatccatc cctctttttt tcattctttc tttattataa
    39181 gaaaaatatc aaaaaaatgc gactagatag ctgaaataaa aataattctt tcaattaggc
    39241 tattggacaa aaaacttttt tgatcataaa gtacaaaact atctcttata tgtcatgatt
    39301 attttctaaa tatttttccc atgcttcgtc aaagatatcc atggacggca aatagtcgac
    39361 attcagttcc agataattag aaatttcttc gtagctagag ctgtgcttag gaaattggat
    39421 gtctttaccg gcttctgtag cgaaaacaga taaagcatca tgtgtgccac cgcctcgcag
    39481 tgtcattaaa taatgaaaaa agcttcgatt cacccttcgt tcctccaatt ttcttcgata
    39541 aaggcagccc ggcgtgcatg gtttctttta aaattttcag gatgcttttt ataatactct
    39601 tgatggtctt cttctgctag ataaaatggt tgggctggtt cgatttttgt aacgattggc
    39661 tgttcgaaac gtccactttc agctaactgt ttcttacttt tttcagcaat gatccgctgt
    39721 tcttctgtca aataaaagat caccgggcga taattgtcac cgcgatcctc gaattgtccg
    39781 aaagcgtcag ttggatcagt ttgctgccag taaagttcta ctaattgttc atatgaaatc
    39841 aatgttggat catagataat ctccactgct tctgtatgtc cagtcgtttg gctttttact
    39901 tgttcataag tcggatctgg tacatgccct ccagtatatc ctgacatcac tgtatggata
    39961 ccaggaagcg tgtcgaaagg ctggatcata caccagaagc agcctcctgc aaatattgct
    40021 cgttccatta tgattccccc tctaatacta ctcatccgat gattttttat tttcttttgt
    40081 cttgctttca gtactgctgg tgctagtttt gttggtattt gagttgtttg aagcatcaga
    40141 ggtatctttt ggcaaatata gactaaaccg aatgtcatca tttactaagt cgattttatc
    40201 tgctttaata tacatcccgt tttgcattcg gaattgatcc aacctaagca tgatagtcag
    40261 atcatctgta ttgacttcga tccaatctgg taatttatag tttctcttga tcatattcat
    40321 cacatctttg attggcaaac tcaatgttcc gatagaaaga cttctagctt ttagttggac
    40381 atttccgttt tccatcacat acggatcaaa atataaatag aaatcgatag gaaaacctag
    40441 tacttcgaaa gtaccattga gtagtgcttc attttccaaa taaaatttat attcaatatc
    40501 actatctttt tgatactcac taaggaaaaa gctgatgatt tgattgactt tttctttatt
    40561 tgaattgatc gttaagacag gatctccttg tctttccgta agagctggta tttctgggag
    40621 ttctggttcc cgattagcaa aaatacggct gcctaaaaat acggtcgaac caagtactac
    40681 cccaagaagg ataaggaagg cgaatttcca gtaatttgtt ttctttgttt tgtttgaaga
    40741 tacgtcagat cttgttttca tgtttattga tcatcctcct tctctaacca ttggttttgt
    40801 gtctcgatca gctgatctct cactgcattt gccatcaatt gataacctaa attatttgga
    40861 tggaaatgat cttcttcata gagcacatta tttttgatgc catttagatt ttctgtcgtg
    40921 ctagttgttt gatctgttcc ttcttctgtg acacctactt cctgattcaa tccttgataa
    40981 agcaaatcat tgattgggat aaagtagcag ttcggcattt tttttgtcac cgtttctgtt
    41041 cctttgttcc aattgttaac aattgtctgc atgtcagtga tctcaggaaa gttcaaataa
    41101 aatggattgt agatgcctaa aatgtaaata ggtgcggttt tattgaggga tcgaaattct
    41161 tccaatagtt ctgtgacatt ttcctgatag tttttcagtg gctttttaaa ggaattgacc
    41221 gttaacccga ataaattatt ttggataact ttcatcaaat cattaccgcc aacagtcagt
    41281 gtgataaaat cagctgtttt gatattgttt cgaatttctt cttttgtttt tactcgcttt
    41341 aagatctggt cacttcgttc accatttaca ccatagtttt ctgtttcaac cgcggtcaaa
    41401 ttataacggt cttttagatc atttgcgaca aggggaacga atcctccttg cttggtttga
    41461 tctcctactc cttcagtcag cgaatctccg atagctatgt agtgaagttt ttctttttta
    41521 tttggatctt ctctcacagt agttactggt ttcattagtg ggccagcttt cggtatagaa
    41581 gcagctaaac ctgcatagat gatgatcgca attaataatg ggaacaaaac gaggatcaaa
    41641 tgtcgtttcg ttaatttcat tttttcacct cttgtattcg attggttcta atgttatcaa
    41701 aaattttatc aaaaaggtag tctttatgaa aaaagaaaac aattattttc ctaattttat
    41761 aaagaaaaag agaataagct gcaagccttt caggctgagg gcttatcctc ttttcgacta
    41821 atctacataa tacatgattg caaacgcgtc tttaccagta tgcgtagcga taaccggatt
    41881 cgtatgcagt acagggatat gcatgtccgg gaataattct tgcaaaccct ctttgaattc
    41941 ttgcgccaat tcttttgcat ccgcatgtga aataccgatt tgtcgcacat ttggcaattc
    42001 tttcagttca tttttcaaat tattaaacca tttatcgaac gttttctttc ctcgcccctt
    42061 agttacaggg attaattcag aatgggcgaa attcatcacc acgcgtatgt tcaaaacact
    42121 agacagcaaa ccagttgttc ggctgattct tccacctttt accaagttat ctagtgtgga
    42181 tattccgatg tataattttg tattgtcttg tacttttttg acttcttcaa ggattttctc
    42241 tactgtttta ccttcttttg ctaattcagc tgctcgaatt acctgaaaag ataatccttg
    42301 gtcagtggta tcactgtcga taaccgttac tttcgttttt gttagattac tggcttgtct
    42361 tgctgcttct actgttccac tcaagccttt tgtcatatgg atcgaaatca cttcactgcc
    42421 gtcttctcct agctcatcat acatcgagat gaattctcca attggtggtt ggcttgtttt
    42481 gggcagattt tttgctttcg ccatcatttc cataaatctt tcgccgtcta gttggtcatc
    42541 atcgggatat actgttccgt cgatcatgat ggatagcggc atgacacgaa tgcctaaagc
    42601 atcgcgtaca tttttttcca tcgtacatga agaatctgtt acgattttta catttgtcat
    42661 tattttctct ctctctttct ttaacaagat gccttattca tgttaaacta catgtaagac
    42721 aatttctatt tttagtataa cagacaaata atgatttttc attaattaca cctagtaaag
    42781 gagccgtttt catggaaaaa acgaaattta atcgaacgta tgaaatatta aatgaagtgt
    42841 ttaatgcagt cacccatgga attgggactg gattgagtat cgcgggacta gtggttcttt
    42901 tagtaaaagg tgcccacttg cattcctccc tccatattgt ctcttatgct atctatggat
    42961 cgatgatgat tcttttattt ttaacgtcta ctttgtttca ttcattgatt tttacaaaag
    43021 caaaaaaggt gttccaagta ttcgatcata gttcgatttt tcttttgatt gcaggaagtt
    43081 atactccttt ttgtttgctg agtatccgag gatggctagg ttggacttta tttgtattaa
    43141 tctggttgtt tgcgattctt ggcattatat ataaagcgtt gacgttgcat aaacgggaga
    43201 gagtatcaaa agtatctacg atcatctata tttttatggg gtggctctgt gtcgtggctg
    43261 ctgttcctct ttatcactct cttggaatga ctggtgttat tttgatggta gcaggcgggc
    43321 tttcttacac gataggcgca ttcttttata gcttgaattc tatccgctat atgcatgttg
    43381 tttggcattt gtttgttatg ttaggtgcag gttttatgta cttctctgtt ttattcttta
    43441 cttaataaaa aaaataaagc tatggatggg acagctctaa ataacagcta gtctatccat
    43501 agctttttta tatcgtcaat tcgcctgtcc cgctttttac aggattctca ttacgctgat
    43561 acgtttcaaa ttgatgcgga taacgatttt tttcatccat ttctccttga ctagtattga
    43621 tcagtgacca atcagaccag tcaacaggtg gaaaataagc atctccatcg aatacatgat
    43681 ggatgactgt acggtataat atcgtacaaa atggcagaaa ttcttgataa acagctgacc
    43741 ctccagcgat gaaaaagata ccgtctgttt ctttttccag agcaagcacg tcttccacac
    43801 tatgcatgac atgcacgcct tctgctttat aggaagaatc tctcgtcaaa acaatcgtct
    43861 gacgattcgg caacggacgg ctacccatcc cttcgaatgt ttttcgtccc atcactagtg
    43921 tatttgcttc tgtcatttgt ttgaagaatt tcagatcatt tggcaaacgc caaggaagac
    43981 ggtcttcttt tccaatcaat ccgttttcat cctgtgccca aattgcagct aacattttct
    44041 catcctttct gattctaaac agcgatagga gctttgatcg ccggatgtgg gtcatatcct
    44101 tctaattgga tatcttccat ctcaaaatca aatactgact gcttttcctg attcaaaact
    44161 aaagtcggaa atgcgcgtat ttctcggctc aattgttctt tcatttgttc gatatgattg
    44221 atataaagat gagcatctcc taatgtgtga acaaattcgc caaccgctaa acctgtttca
    44281 tgtgcaatta ggtgagtcag caacgcataa cttgcaatgt tgaacggaac gcctagaaac
    44341 acatccccac tgcgttgata caattggcag cttagccgtc cctcttgaac ataaaattga
    44401 aacatcgtat gacaaggagg caaagccatg ctaggaacat cttccggatt ccatgcagaa
    44461 acgatcaatc ttctagaatc aggagtcttt ttgattgctt cgatcacttg tttgatttga
    44521 tcgataaagc caccgtcttt tgtttcccag tgacgccatt gatagccgta gatgtgtcca
    44581 agatcgccgt atgtttcagc aaaggaatca tcggttagga tcttctcgca aaaaagcttg
    44641 ctctgctttt tatattcttc attgaattca ggatctgtca aacatctatg gccaaaatca
    44701 gtcatatctg gtccattata gtctggactt ttgatgtagc gttcaaatgc ccattcatcc
    44761 caaatatggt ttttattttg taatagatag cggatattcg tatctccttt taaaaaccaa
    44821 agcaattcgc ttttgatcaa tccaaaaggt actcgtttcg ttgttaacaa aggaaaccct
    44881 ttttgcagat caaaccgcat ttggtatccg aataagctta atgtgcctgt gcctgttctg
    44941 tcttctttac gatgcccttc ttccaacaat tttcttccta agtcaagata cgcttgttcc
    45001 atcctttttc ctcctaatct tctacccatt cactcaagta ttcccaccgt gccatttttt
    45061 cttcaagttg tgcttctgtt tcagatacgt cgttttgcaa ttcttgtaat cgagtgaaat
    45121 tatctccttg atgattcatc tcttcttgga gcaatgagat tttttcttca agttctgcaa
    45181 tctcatcttc aatcgtttcc cattcttttt gttccatgta agataatttc ttcttttcag
    45241 caggttcctt gctctgtatt tttggtttcg ctttttcagc aggctgctgg gtctcttttt
    45301 gcttcagtaa ataactggac atgtttccgt aataaagttc ttgttttccg tttccttgga
    45361 atactaataa cttatctgct accttgtcca agaaataacg gtcatgggaa acagtgatca
    45421 cagcacctgg aaaacttcta aaataatctt ccaaaatcgt caatgttgct atgtccaaat
    45481 cattggtcgg ttcatccaat aataaaacat taggttgctg aatcagcagt ttcaacaaaa
    45541 ataaccggcg tttttctccg cctgaaagtt tgcctatcag tgtcccatgc ataaatcttg
    45601 gaaataaaaa tcgttcaagt aattctgcta ctccgatttg actgccatct gctgtttttg
    45661 cttcttcagc agcttcttgt aagtaagcaa tcatccgttt atctggtgcc atttcttcat
    45721 tttcttgtgt ataatacgca agatgaaccg tttcaccgat agacattgta ccgctatcca
    45781 ggggaattct gccagctaga atattaagca atgtcgattt tcccgcacca tttttaccag
    45841 taatacctag tctttcccga gattgaatca ataaatctaa atgttctagc agtgtttggt
    45901 catttatacg gtaactgcca tctttgattt ccagtacttt tttccctaaa cgttgtgtcg
    45961 ctaggttcag ctctaaatca tcttcttggt ttacttggta caagttctcc tttagatctt
    46021 cgaaacggtt gatccgtgct tgctgcttgg tgccacgtgc ctgtacgcca gccctcatcc
    46081 aagctaattc ctgtttataa agccgcttgc gcttttcttc ttgttctact tctacacgat
    46141 cacgttctgc tttttctaag acgtaagctt cataatttcc tttatactcg tataattttc
    46201 caaatgaaag ttcgaagatt cggtttgcta ctctatctag aaaataacga tcgtgggtaa
    46261 ccatcaatag tgcgccacgg tattgtttca aatagttttc caaccactcg atcgcttcat
    46321 aatctaaatg gtttgttggt tcgtctagta atagtaaatc gggttcatca atcaacactt
    46381 gcgccagact aactcgtttt ttctgaccac ctgataaagt actgattttt ttatctaatt
    46441 cactgattcc taatttttgc aaaataatct ttgcgttggt atctgtagtc caagcatctt
    46501 ctttattcat ttgttcttct gctttagcat aacgtttttg cacatcaggg tcttctccgt
    46561 tttcccctag ttcgatcaat gcttcctcat atgctcgaac agtttggatc aaggggctgt
    46621 ttccttgaaa gactgcttgg agaacagtta attcatcgga aaattcagct gcttgagaaa
    46681 gataaccaat acggtaatca gttggataaa acactgtttg ccgatcaccg tcgctgctat
    46741 cgataccggc aataatattt aagagacttg ttttacccgt cccgttcgtc ccaatcaacc
    46801 cgatacggtc tttttcgtgg accaaaaaag aaatctggtc aaacaaatct ttttcaccat
    46861 aagttttttt gaggtcagtt acttttaatt ctttcaacat gttccctcct tatcttggat
    46921 attgtatcat aaaaatagtg aacttcagga aaattttttt ggtatttgtt ctttttgtgt
    46981 tctcaaaaaa agaacaggac cgattcgatc ctgttctgat atgttttgtt ttttataaaa
    47041 cttgaaaatt tttacctttt tattttattg gactcgtttt ttttgacttt gctcgaaacg
    47101 caaatcggaa agaaaagtta tcagatggtt tgttcatcgt ataagattct aacaaattga
    47161 tattcctgcg atagctgttc gcagaaaacg tcgtgatttt ttcagcaact tcgtattcat
    47221 caatgatttt tctttcaaga taataacctc ttagcatttt tttcgtaaac agactatctt
    47281 gctggatcat ccacgaagaa atcaaattcc ccgagttcat ttttattcct tcaagtttgc
    47341 gttgctggat aaaaaattga accatcgttt catcataaat atcagtcaag ttatctaaac
    47401 tttcaataat caactgagta tttttttgat atgtctctct gatttcttgg atatcttcat
    47461 cactaataaa tgtctgacga tcagcatatc ttctttgcca aaacattttc ggatggagaa
    47521 cgattcgcat taacctacgg acaacaatga accaaaagcc gataaaagac aaaatctggc
    47581 ttgtgataga atgttcgaat cgagaaagaa aacgggagta aaaacgataa ccattagaag
    47641 aaagcttgcc cgaacgataa ctttcatcca atccatcccg ttcgatcgac aaaatcagtg
    47701 cttgtatttc ttgtacttct tgcttttcat catcggttaa atcttccaag tacagatcac
    47761 gtatccgttc ttgataattt tctatcactg cttcagtggc taaaaattct tttgtattac
    47821 gatcaatttc ctttatttct tttcgcaaaa cttcaacgac ctcttctaaa atcatcaaag
    47881 cattcaaatc cgtgcttttc gcttcctctg tttccgtcag cataggcaag acaatgatcc
    47941 ctatgaccaa agtcactaag atgacacccg ccgtcagaaa caaaagcaaa gaccgctggt
    48001 aaaacatcat attattgatt gaaaatggca aaataaaaat cgtagccaaa ctgactgttc
    48061 cctttacacc gccaaatgtt aagatcaaga tctcgttcaa ctgttttttg aactttttac
    48121 tgccatcttt gaatacataa aaaagactga tagaaatgaa tctgatcaca aaaagcatga
    48181 cagagattaa tacgataatc gctaataaaa gaccgtttgg atataaaccg tctccccata
    48241 ctggcgagaa cacttgcgtc aattcgattc ctaaaaatat aaatactaat gcattcagtg
    48301 taaaagcaat agttgtccat gtactgtggg acaagctcga caattctgca tcaaacacag
    48361 agattttcct aaaaccagaa gcttggagaa tacctgctgc cactgcagca atgattccag
    48421 atacatcaaa tgcctctgcc aatacatagg ctagaaaagg aagcaaaagt tcgatcagca
    48481 gataccctgt gacatcttgt gctgatgctt tttcgatcaa atgaattatt ttttgtttga
    48541 accagacaag caaaaagccg atcaaagctc ccccaatact agaaactact agactcatcc
    48601 ccgcgtttac tgctgaaaaa gatccggtga tcagcgcacc aagagcaaac tggaaggcag
    48661 taacaccaga tgcatcattc aaaagacctt ctccttccaa aatatgcatc gcctttttag
    48721 ggatattcac tcgtccagaa agagaactga ctgctaccgc atctgtcgga cctaacgctg
    48781 ctccaaaagc aaagcaggca gcaagtggga cacttggcaa caggaatgat aacgtcgcac
    48841 ctaccccgac aagggtcaaa atgactcctc caaatgccaa gaacaaaatt gtcccgaaat
    48901 ttttgagaat cgaagaaata tctgcttttt ctccttctct aaataacaat ggtgcaataa
    48961 tcataactaa gaacaattca ggttcaaaat cgattgattg tccccactct gtcagaccta
    49021 ataccactcc aaggaaaatt tggatcagtg gagctggaat cattggcaaa atgcggctag
    49081 ctatgttcga taaggtgatc gttactgcaa atacaataac taactcagca aattccatcg
    49141 tccatcccct ttatttttta ttttgtgtaa gcatttttaa aaattgttct tttttcttta
    49201 aaattttggt ttcgactact tcaacctgtg tttggttccc ctctaattca cactgtacac
    49261 gttttgactc caaacgaagc agatcatgtt tcagacgttc caactgacga tacatcaata
    49321 tatttctttt acgcaactta caaagtattt gacggcggtc atccatcgaa agggcgccat
    49381 agcgatcatg caacagtttt ttttgttgtt caaaactctc tctcattttc cagatctcct
    49441 atacacaaac ttccatcatt atagcaaagt tctttttgga tgaaaaatat ttcattgttt
    49501 catcgtttat tgctagttag aaatttccat aaatttttca acgcctcatt ctattccaaa
    49561 tagtatcaga tatcaagtaa aacttaagaa agataaaagt ttctgacaaa aggatgttta
    49621 ctttcccatt cctgcctttc ttgttctttt atcacaacaa aaaaatgggg ctgcgacaaa
    49681 aatcttgtca cagtccctta ttctgaataa acggtgtgga agagacagcc tatcagtagt
    49741 aataagacac atctctttca cagcctcatt tttgcgtaaa aatcgattta ttcgaaaaat
    49801 tccccgtata catcttctac acgttgatct ggattgatca cgatatacaa gttacctgtt
    49861 ttttcgctga tttttgttga ttgatattga ttgtctaatc cttctgttcc tttatctaga
    49921 tatgggaagt acacaagatc aggtgtgcca tttcggtaaa ggatttccat tcgctcgata
    49981 tcttcgtatt tcaatgcgcg attaaacatg cccatttcca gtccgcctag gttgatatca
    50041 tgtgtcgcaa ctgcgtcccc ttcatggaag atttcgattt taaatccagc acacggatgg
    50101 atttcaacaa attcactgcc attgattcgt ccaaaacttg ttgtgatttg tttgatccaa
    50161 agatcgccga tatgacggcg gttgatcgtc caggtttctc catttctaaa ataaaatttt
    50221 agcgctgtca tttctttact cattaaaaag actcctttat gatgtaattt attcttgtac
    50281 tacctcagtt tagcacaaat ttatgtaagt ggtcacatct tatgtttttt cttctaatga
    50341 cgtatctgcc cactttaagt agccaacaaa gctgagcaga tacagtctag tgttttttaa
    50401 atcaattttt ctttcgataa aaaatccaaa acctgttttt tatcattttt tattctttgt
    50461 tctacgacgg ctttttcagc taattgcaaa gcttcactaa cccacttacc aggttttttt
    50521 ccagtttctt ctagcaagat tttaccatct actgctaatt cgcttaatga cttgataggt
    50581 aaacgatcat aggattctcc tacggcatcc atctgaggtg tttcgtcaaa atagatcatc
    50641 aattcttcta cttgcagtgc atgttttttg cctaagaagt acaattcgaa tggttccaaa
    50701 gctccagttt ctcgttgtcg tagtccttgg acaagtgctt gaacgtcttt aatcatttgg
    50761 ttagaacact tccacgattt caaaaaggaa cgaatctcat tttcttttag atccagttgg
    50821 ctgatcaata atgcccatgc ttggctctct tctttcaatg ggacggatgg taattcagca
    50881 aaacgtaaaa gtgcttcgcc ttcttctttc aaaccgggac agcaaatgta gcactctgtt
    50941 tcaataaatg catggattcc cgcggcccgt tcatttccca agagcatctt gatgaattcc
    51001 acatttatac gttctacaga tattttacct aatagctcgt ggttttcttt gatggcgtag
    51061 aaggtttctt cctctaattt gaaccctagt tgactgacaa aacgcaaccc gcgcatcatt
    51121 cgtaaggcat cttcatggaa ccgctcatga ggattgccta cagctcgcaa gatctgttct
    51181 tctagatctt gcagaccatc gaacaaatcg atgatttctc catcttcttt caaagcaaac
    51241 gcattgatcg taaaatctct tcttttcaaa tcttctgcca acgaacgaac gaattcgaca
    51301 tgatctggtc tacggtagtc ctgataagtt gattccgtcc gaaatgtggt gatctcatat
    51361 tgttcatcat tttctaatac caacacagtt ccatgttcga tcccaatatc tatcgttttt
    51421 ggaaaaagct gtttgatttc ttctggaaat gcgcttgttg cgatatccac atcatggatt
    51481 ggctggttca gcaagatatc acgaacactt ccacctacaa aataagcttc atatcctgca
    51541 ttctctaatt ttttcagaac tggaattgcc ttttggtatt ccagaggtaa ttgttttaat
    51601 ttcatttttc caacctttcc tgcgtgtttc ttgtcctgag ataaagactc agttgcatgg
    51661 tgactgtttg acaagtccgt ttcagagtct tcaaggccag gaccacttca tcttgtttac
    51721 tcgtccttac gctcaaagcg attatggtct ctttgattga atttttccat gtttttttca
    51781 aaaacttcag ttaagtcgat attcaatgaa ttagccatga tcatcgtaac gaataaaaca
    51841 tcaccaagtt cttctgctac cgagttaact ggttcagaag cctttttgct tttttctcca
    51901 taagtgtggt tgacttctct tgccaattca cctacttctt cagttaatcg agccatctga
    51961 gctaatggag agaaataccc caccttgaat tgctggatat attcatccac ttcctgctgc
    52021 atactgtata aagaacgctt tttatccatc tttttccctc caaaactatc ttaccaaaac
    52081 tttaacgcaa atcctagata agagcaattg agaaaatcga atttccatgc tacatttagg
    52141 aaggaatttc taaatggaaa ttctgtgaaa atacataatt gaaagctgga attcatatgg
    52201 tcaaacgaaa aacagtaaaa gaagttcttt ttatcattat aggaacaagt atttatgcat
    52261 ttggtcttgt ttacttgaac atcgctaatc atttagcaga agggggagtc tcagggatca
    52321 ccttgatctt aagagcttta tttggtattg atccagctta tacgacttta ttaatcaaca
    52381 tcccattgat tttactagga ggaaagatcc tcggtaaacg ttccttggcc tatactgttc
    52441 taggtacact ttctttgtca ttctttttat ggatctggca aagggttcca ctagaaatca
    52501 atttacagca tgatctactg atcgtttctc tacttgcggg tttagttgca ggtgtaggaa
    52561 gcgggatcgt ctaccgcatg ggtggaacaa caggcggcag tgatattatc gctcggattt
    52621 tagaacaaaa ttacggcatc actatggggc gttccctatt ggcatttgat atcatcgtct
    52681 tacttgcttc attaacctat atcgacttga aacgtatgat gtatacgttg attgtttcgt
    52741 atgttttcag tcgtgtgatt gattcgatct tagatggcgg atattctgca aaaggtctac
    52801 ttgtcgtctc caacaaaagc gaagagattg caccactact gatgaccggt ctgcaaagag
    52861 gtgtgacttt cctttctgga gaaggcgcat tctctggtaa ttcaaaaaaa atcatctata
    52921 tggtcgttag ctctagtgaa ttaactgaag ctaagaggat cgtccacgag attgacgaaa
    52981 aagctttcct ttcaatcatc aatgtgcatg aagtggaagg gcaaggcttt acttatttga
    53041 agccacagac aagattactg aaaaaactat aagaaaaaag acaaagatag gctatgagga
    53101 aagattccac atccagctga cctttgtctt ttttagtact atactatttt taactaattg
    53161 ttatgttcac ttacccggtt acttttcttt tgtgtctgca aaaggatctt tcggttaact
    53221 tcatcagata atttcaaaaa agcatcccta tctccatctt ctagtgcttg atcgatttga
    53281 gcataaagca tttttagttt tgcctcttct tctttttctt gaaaatatcg ttcaattaat
    53341 tcagtatctt cttcactgac tgaagaatcc caagaagaaa atggattgtc ttctaagata
    53401 gatagatatt ctcttgtctg ccaagcattt tcgaatatac attccacata taaaggcttt
    53461 ttccaattca aacggatttc atgaaaaatc tggtctgtgt ccgtaaattc ttttccctgc
    53521 aaaaacaatt tcatgggttc cccttcaaca gatagatcac tgatctgcag tcctcgatcc
    53581 gcaaaattcg ccccttcaac aaagtggaca ttgcttaaaa tcgcttcatg attggcaaga
    53641 taattcaaga tccaaaaaac ttctcttcgg ctaaaagata catgattgac catccacgtt
    53701 aaaaaattct tcttttcccg tacatcaatt agcatttttc tcacctctct gttaggtcat
    53761 ctaataatga cagtgcctcc atatctcctg gttcaagtgt taaataataa gtcaataatt
    53821 cttgcgctct tttcagctgc ccttcttctc ttaagaaaaa ggcatactct ttcaagaaat
    53881 ctggttcatg tgatagttca tgataagcct gttcatagtg tacagctgca acggtaaagt
    53941 cttctaattc attataagca tgggctaggt tccattctgc ataaggatta gcagtttctt
    54001 ccatctgatt gatcacttgt atcacatctt catatctttc atcatccaag taaagattac
    54061 ttaaagtaag taatgtttca tcttgtttgt ctcctacttc taaagctttc agtaaaagtt
    54121 cttctgctcg ctgtctatca tgcagacgga aagcattttc cgaggccagg tgataaagtt
    54181 cgacttggta aggattttct ttgattcctt cttctaacac tgtttgtgct tcttcaatca
    54241 tttcttcttc ttgaagagct tgtcctagat atagatataa cgattgataa tgcggattaa
    54301 cttctcgaag ttcttccaga tagttgattg cctgctgatt ttctttcaat tgaagattcg
    54361 taaaagctag ctggaacagt cgatcatctg tcctttcttc tttcagtgct tcttctaaag
    54421 gtacgatagc tgcttcgaat tctccttgca tacttaagga ttgtcctaaa cgttcctgca
    54481 tcgagattcc tgaaatttca tttatcccgc ttgccaacaa tgtttcataa accactgctg
    54541 cctctttgaa acgatcaact gaaaaataca attcagctag cgcaaactgg atcaatggtt
    54601 catcaggaag caacccagct gcttctttca attttgcttc actcacttca gggattccga
    54661 taacttggta caaatcagct atcgccaata agctttgcgg atagtaatca ctttgcttat
    54721 ccactttttc caggtattca aaagctaagt cgatctcatt atcttcgatt gcaatttctg
    54781 ctaacgggat gttcagtccg tcattttctg ggtattggtt gatcagttgt tcaaaaatct
    54841 gttttgcttc gatcaaaaag ccaatagcca gcaattcttc gcctagttca gctaatatat
    54901 ctgctgggtc ttcttttaat gctttttcta aaaagatttg tgcttgtgac aagtcttcat
    54961 ctgataaagc ttgcaacatt ttttcgctat ttgtattcat ttcaattccc tcttatctca
    55021 ctgacgattt gttgaaatac cgtcattgtt ctcaataatt ctttttcgtt tggatgttgg
    55081 tatccgtcta ttatacctat tttttctaaa acaagtattt ttttgctttt ttctgccaaa
    55141 aaaagaactt tttccaaata ctccatcttt gaaatctgtt ccagccagtg gattggatag
    55201 ccaagcaagt ccagccacac aaaaaagttt tttagttgga aatcaaaagg atatgcttgg
    55261 agattccaca cgaaatgaaa catcattcct aaaaattttt tcatactagc agaaagtaga
    55321 tggccatttt cggtcagata aaaagcttgt tcaaacagtt taccataatt tgacaggttt
    55381 tctgcctcta attgataaaa atagatcatt tcttcgatca tcccggcaaa cggccgagtc
    55441 gttaattgct ttttatttgg atagttttta tacagatttt gcaaaaaacg atgatcacaa
    55501 atcattccgc aacagataaa agtcaaaaag tcaatctgct ttccgtccac ctgccgctcg
    55561 ctgattgttt gatcataaac gatgcgttct ggcagattga tggtttgcag cactacacga
    55621 tttggtagct gcaaaatcgt ccgctgcggt gttaatgctc ggcttagaga acggatcgat
    55681 acagggatca tccatagtga tgaatcaagg gttgtatgtt tttgaaaaaa acctgccaga
    55741 tccatgatcc cttcatttcc aaatccgatg ataaacatgg attgattttc gggatagcgt
    55801 ttgacgaaat caagcaggtt ctttaattct gttaaatgat tgcattgagt gttggcacaa
    55861 atataccagt cattgtttgc ttgatttgca aataacgggt tgatcttatc tgcaaacaaa
    55921 tcataatagc gctgattcgt taaaaataag attggctgat caatggaaag ttctcttagc
    55981 tgactgacta gcgtttctcc gtaaaacact ttcgtcaacg catcttctac ttgataatca
    56041 agttccatac gcatccctcc tcttcttatt tttattttac cattagtaag caaattctag
    56101 aaaagataag agcaaagctc acctcataac ttgcaaataa ataaaaatta aataaaatac
    56161 atgtgttttc tatgtatgac atacggattc ggaatctctg tctcttattt attccttttc
    56221 tgctaggaaa taaaaagaaa agcacttgta gccctagagc cacaagcgct ttttcaactg
    56281 tcttatttaa cagcgtcttt taatgcttta cctggtttga atgcaggtac tttgctagct
    56341 ggaatttcga tttcttcacc agtttgtggg ttacgacctt tgcgagctgc gcgttcgcga
    56401 acttcaaagt taccaaaacc gattaattga actttttcgc cgttagctaa agcatcttga
    56461 atagttgaaa atacagcatc tactgctgca gttgcatctt ttttagttaa atcagtagct
    56521 gaagcaactt tttcgattaa ttctgctttg tttgccatgg atagattcac ctcctccaca
    56581 agagatatga tagaaatatc atttagttaa aactttctga gtggtccaga agtttaaaaa
    56641 gaaatattga ttaacttcaa tattctgtta tcacgatatc atatgaaccg cttaatagca
    56701 aggtttttac caattttcac atgctttttt tagtcataga aacgtaacaa acgaaactgt
    56761 ctttttcttt tgaaaaaaaa acgtcgatat ggtaaaatgc ctattttctc ctacgaggga
    56821 taattcggat ggacgtccct tcaaaagtaa atgcttttct gatttgattt tctaagaaac
    56881 gttcataaga aaaatgcatc aattcctctt cattgacaaa aacgacaaat gtaggtggtt
    56941 tgacagcgac ttgtgtagca taaaaaatct tcaggcgttt tcctttatct gttggtgttg
    57001 gattgattgc tacagcatcc ataatgatat cattcaacac agccgaagag atacgaagat
    57061 tctggttcat acttacttgt tcgatcattt caggcagacg ttccaaccgt tgtttagtca
    57121 ctgcagaaac aaaaacgatt ggagcgtaat caagataccg gaattcatca cgaatctctt
    57181 gttcgaaatc acgcattgta ttggtttctt tctttacaag atcccattta ttcacgacga
    57241 taataattcc acgaccagct tcatgggcgt aacccgctac tcgcttgtct tgttcccgaa
    57301 tcccttcttc agcattcagt accatcaaaa cgatatcaga acggtcaatg gcacgcattg
    57361 cacgcatcac gctgtatttt tcagtatttt cgtatacttt tccgcgttta cgcataccag
    57421 ctgtatctat cattaagaat ttctgaccac tttcagaaac gaagtgggtg tcgattgcgt
    57481 ctcgggtcgt tccttcaata tccgaaacaa ttacacgttc ttctcctaaa atcgcattga
    57541 tcaaagagga tttaccaaca tttgggcgac caatcaaact aaacttaatc gtgtcgtcgt
    57601 cctcttcttc agtctcttca gagaaatact tcactgcttc atctaaaata tcaccaatcc
    57661 ctagtccatg gcttcctgaa acaggataag gatcgcctag ccctaaggaa taaaattcat
    57721 agatatcgtt tctcatttct ggattatcta ctttattgac tgctaaaatc actggtttat
    57781 tacttctgta taaaattttc gcaaccatct catctgcgtc tgtcacgcct tcgcgtccgc
    57841 tgactacaca aatgattaca tctgcttctt caatcgcgat ttctgcttga tgcttgatct
    57901 gatccataaa aggttcatcg ccaagatcaa ttccgcctgt gtcgatcacg ctgaattctc
    57961 gacctaacca ttcacctttt gcataaatac gatcacgagt tactccagga gtatcttcga
    58021 caatcgagat acgctcacca gcgatgcggt taaaaatcgt agacttaccg acgttcgggc
    58081 ggccaacgat tgcaattgtt ggatttgcca tattatttcc tcctcacaag tttccaatct
    58141 cacttagttt aacgaatgca ttgccaactt tcaagcatag attgtcaatt aaacgaagta
    58201 tttttattcc ttattgaaat actaatcgct tttcaaaaga aaaactgaga caaaagcagc
    58261 tgctttcatc tcagtcacag atacaaaatc aattattttt cagaatcatc ggttgctttt
    58321 tcttctactt cttctttcaa cgcatcacct aaaatgtctc ccatagtaaa tccagtattt
    58381 tcttctggta attcataaga ctcaacattt tttggttctt cttctgaagc tggtttttct
    58441 tctaaagctt tgatactcaa tgcaatacga tgttcttctg gatggatctc taatactttc
    58501 actttcactt cgtcaccttc atgaagcact tcatgtggtg tcgcaatatg tttatgtgaa
    58561 atttgagaga tatggactag cccttctact ccagggaaca cttcaacaaa ggcaccgaag
    58621 cttgtcaaac gtttaactgt tccgtctaat actgtgccaa ctggagcttt tgtatcgatt
    58681 tctgaccaag gtccaggctg tgtgtctttg attgacaagg aaacacgttc ttgttcagga
    58741 ttgatagaca acactttgac atttacatca tcattgacag ccaatacatc acttggtttt
    58801 gctacatgac tatgtgaaat ctctgagaca tggactagac cgtcaattcc gcctaggtcg
    58861 acaaatgcgc caaaatcagt aagacgtgca acacgtccac tgagaacatc tccctcatgg
    58921 atagttgaaa gaatttcttt tttcttttct tctctttcgt tttccactac cgctttatgc
    58981 gataagatca aacgattttc tgatggttcg atttcgatga ttttaaagct caatgttttg
    59041 cctttatagt ctgaaaagtc tgcaacaaaa tgatcttcca ccattgatgc agggacaaaa
    59101 ccacgtacac cgacgtcaac gactaaaccg cctttgacaa catttgtaac aggtgcttcg
    59161 atgaccttgc cctcttggaa atctctttcg atatcttccc aaactttttt agcatctaaa
    59221 cggcgttttg aaagtagata gctgccgttt tctttatctt tgccgatcgt actgataacg
    59281 actaaatcta atacatcacc gacttttact acttcgctga tatcttctac cggcaaagtt
    59341 gataattctt ttgccggaac gactccttca actccagccc cttcgattcc gacaatcact
    59401 tgtttgtctt caatgactaa aacttcgccc ttaacaacat cgccaacttt tacttcttgt
    59461 acgcttttca ttgcgtcttc cattgactgg ttgttctctt gattttgatc aaattctgtc
    59521 ataacacttg tcctcctaac caacattctg ccgtaagtac ggtactgttt ttagtttaat
    59581 tgattattca aaaaaaataa agcgatttcg ttcgttttcc ttgaaaaaac aattgttttt
    59641 catttttttt cttaatttaa aaaagaagat aacctttttt caaaacaaca gcttttattg
    59701 ctgcaacgac ttctggaatc gatttgccag tcgtatcgat acgaacagca tcctctgctt
    59761 gcttcagcgg agagacgtcc cttgttgaat cataatggtc tctttcctgt atctctttcg
    59821 tcagtgtttc aagatcagtc ggaattcctt tttcttggtt ctctttgaaa cgtctttctg
    59881 cacgctcact tacgcttgct actaaaaaga ttttcacttc tgcattcggt aatacagctg
    59941 tcccgatgtc tcttccgtcc atgacaacgc caccgcgttc ccctattttt cgttggacag
    60001 caactaattc ttctctgact tttccatgtg cagagacttc agaaacagct tttgtgacat
    60061 ctggttgacg gatttctaaa gtcacatctt ttgatgctat gaatacatgc tgtccatctt
    60121 cttgttgcga aaaagagata ggatactttt tgatcagcga aactagccct tcttcatctg
    60181 aaaaagatac attgttcgta atagctaaat aagttactgc gcgatacatg gcaccggtat
    60241 ctgtataaat ataattcaat tcttttgcta atatcttggc aacggtactt ttcccagatg
    60301 aagcaggccc gtcgattgca atactgattt gtgtcatgat ataactcctt tttctcagaa
    60361 aaaaagccgc aaagcgcggc tattattatt taattcttaa ttcttgacca gggtaaagca
    60421 taaagttgtt tggatctaag ccattcaatt caaacaattg atcagtggtg atccctgcac
    60481 gctcagccac ttgttttgga ccttcgcctg cttgaacagt cgttgttgaa ccggctgcag
    60541 ctgatgaaga aggtgttgtt tctgctgcat tgctgcttga atcccctgct tgataagttg
    60601 cctcacttga ggaagtcggt gttgtctctg ctgcaatact gctttctgac gttacacctg
    60661 tatcttgaga cacagtagat tcttccgcga ttgtactaga ttctactgtt gaagtctcag
    60721 ttgactcctc ttttgttgta cttgtagaac tttctactac tgatgtcgaa gtttcagaag
    60781 aagttgctgc tgttgcattg ttgcttgatc catttctgat ccagaaataa gcacctgctg
    60841 gaatagcgat acataagacc agtaaaatca aaaatagcga aagaaataat gtatttcctt
    60901 tcttttgttg tctctgagaa cttcttgatg aaacttcatc atctgtatcg tagattggtt
    60961 gttcccatgg ttcttgtgtt tcgttatttt ctgtagattg atgtctatct tttctgctca
    61021 ctgttttacc tcctaaactc tatcgtgtgt attataccat aggaaaaagt gtcttgtcct
    61081 aaaaaatcaa tgttccatgt tttttttaaa taaatttagt aaaatcgttt cccaatgaag
    61141 ttgttcagtc ttagaaaaaa gcttcctctt tggcagaagt tctgcttttg ctccatcaat
    61201 atcacaacaa ttctgcggct tttcggagag tttttcgcca aaataagcta agatgaattt
    61261 tctgcggcag ttttcttcat taatatagcg aagcatctgc tgcaggcgga attctttttc
    61321 tttttcctga cgtttgagcc gttccaccca attttctggt ttttcagact gctggatcag
    61381 ctccatccat tttttttgca gctcatcaaa gggagcttgc tctgtggcat attccaaata
    61441 aagctcaaaa ctttgtcgct gttctctaga aagttgatta aagaaataat ggatacgttc
    61501 atccccactt tgataaaaaa gaattgctgc actttcttcc tgatctctgc ctgctcgacc
    61561 gatttcttgt acatagtttt ctagactgtc tggcaaatca taatggacca cataacggat
    61621 atcagattta tcgatcccca taccaaatgc attcgtagca atgagaaact gcagctgatt
    61681 ttttacaaac tgctgttgaa gttgtcttct ttgagctgca tcaagaccac cgtgatagta
    61741 tccaactgta aaacgttccc tgaataaatg atacaatcgt tcgacttctt tttttgttgc
    61801 acaataaatg attgccgctc cttgtgctct ttccatgaag tgttcaagtt cttgttcttt
    61861 ttgctgcgtt ttccgaacaa aaagcgagat attttgccga ttgactgatt gtctgatctc
    61921 ttttggtggt cgatcaaata gtacatgacg tatatctctt gctactaaat ctgttgctgt
    61981 cgccgttagt gccagtgtga ccgggtttcc taaaagcttt cggatttttc ctaactgttg
    62041 atattctgga cggaaatcaa ctccccattg agacacgcaa tgagcctcat ctactacata
    62101 taacgcaata ttttgttttt tcagatgctc taaaagagaa ggattagtca acatttcggg
    62161 actcaaaaac aaaaatttat attgcgatag atgacggagg acgtatcttc tttcagattg
    62221 cgaaagtaaa ctattgaaag cagctactcg tttctcccct cgtttttgta attgcgtcac
    62281 ttgatcttcc attagagaaa gcagcggtga cacgatgatg accagacctt ccattaaata
    62341 ccccgtcaat tgatagcaaa ggctttttcc cgttcctgta ggcaaaatag cgagagtatc
    62401 ttctccatca agcaacgcct gaataatttc ttcttggccg ggacgaaatg aatcaaatcc
    62461 aaaatatttt tttaattcat ttattaacat tctgtatcgc ttcctttctc aatagataga
    62521 tttgatacaa acgaaattct ccataatcta attgtccatc tacattccat tcgctaaagc
    62581 gccactctcg cacggaatcc ttatttggtt ccaaacgttc gattgtttct gcagagagaa
    62641 tccactcgta tggaaaatca tcaaaaaaca aggcccactc aataagatga tctgttactg
    62701 ttcctctttt taaatgacgg attgccatga tctggtcaat tgtctgacca ttcataaaca
    62761 tctgcttggt gatcatcatg ctttgattga aattttgctg taataatgaa tcgatcaaag
    62821 cgtgccaaag cgaatctggc cgtttttcga tttgtgctaa caaaaggtgg atacatctgc
    62881 tttgttgcag ataaaccgct gactcatcat tgttttttgc cagctgataa ggaagcagcc
    62941 ctgttcgctc atttccagat aattggttag ctaaaaaatc tgctgcttct tctggtatct
    63001 ccgaaaacag ctgcaccaaa ctctcatacg cagtatcaat caaaatttca cgtggcaatt
    63061 ggctttcact aagccatttt tttagttgga aagtataaaa aggacttgtc tctgctggaa
    63121 gatagtcttg aatacccgtt gccagattag aaattacttg aacagcaaat ttaatgagcc
    63181 gccaactagt ttcccctgtt ctgccatagc ggtcaaaacg caaaccagta tgttctattt
    63241 gatgttcgga caacatatca gcccctgcag gcgttagctt tgcttcattt tcatttattt
    63301 cgatccaacc ttgctgcgca attttttgca aaatttgata aaacttatcc tgcttcaatt
    63361 ctggaaaact gttatggata aacaaaagtt cgtgggtaaa tccataaata agtactgaag
    63421 tcgttcgttt tcccacaagg agttggtaaa gagaactaat ccgcagcttg tgtcctgatg
    63481 aaaatagcga taaaataaaa acaatcatat tattctcctt aagttaggat ggttagaaat
    63541 gtcactacta tgtaaacttg tacctgaacg ctgtattgca tgcggtcttt gtcaaatcga
    63601 agcgccagat attttcgatt atgatgaaga aggaatcgtt ttatttgccc aagaaccaga
    63661 ggctcatcaa cagttcgtga tgccggaaga agaaacatat gtaaaaaaag cgtatcaaaa
    63721 atgtccagtt cgagcgattt tattagaaaa taaaatataa atataaacga aactttaaaa
    63781 acgtacacta agttctctaa acttgaaaat aagccgggat ctgtttctct tgttccgtga
    63841 aatcccgact tattttgaaa gattcatttg ctatctatag ttaattgact agttttttca
    63901 cggaccctat aggacccatt tatattattt caactttttc agccagtttt ccaatgtatt
    63961 gacgatcaca gtttgctggt ctgcgttaga aatttctgcc tctccatctc ctttttgctc
    64021 accatagctg ccaaaacctc catgatttcc gccattgatt gatacatact ctgttctttc
    64081 cggtaaatac tgcttagctt cttgataagc ttcctgattc aatactttat cttttgtcgc
    64141 cgtgatcgat aaaacaggaa cagctgattc tgtcaatgtt ccttttttgt cgggataact
    64201 tgccatgaag aatacccctt ttaaatgttt gtctgaatga ttcttattga cataacgact
    64261 tgccattacg ccacctaatg aatggccacc gatcacataa tcggaatttg gaaaatcttc
    64321 tttgacctta tccgctttgt ttccgcccat cactgctaga tcaagtggca ttttgacaat
    64381 agcgactgaa aagccgtttt ttgctaaatc ttgcgcccaa atactataac tttctggctc
    64441 tacgagagca ccaggataaa aaataagtaa tggagacttt ccatgattct ttttctctcc
    64501 ttcaaaaaat aagtaatctt ctttgttttt tccttctttt accaacactt gcgcttctga
    64561 cgatggttcg tacgtatttt gctgtatata gtaataaccg gctccaccga gtaatcctaa
    64621 aatgatgact aagccaatta gtattcgtct aaatattttc actttctccc accttttcta
    64681 tctgagtgac ccctttttct taatcaagta tgattatacc ttaaaaaaat aagagagaaa
    64741 tgcaaacttt ccagcatcaa ataaaaaaag acggaatatc catttgaata tccgcccttt
    64801 ttgtatgttt a
//
LOCUS       DAXQKX010000009        61713 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.009, whole genome shotgun sequence.
ACCESSION   DAXQKX010000009 DAXQKX010000000
VERSION     DAXQKX010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 61713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61713
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.009"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(134..511)
                     /locus_tag="ACF3MF_000636"
     CDS             complement(134..511)
                     /locus_tag="ACF3MF_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926661.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            767..1495
                     /gene="purC"
                     /locus_tag="ACF3MF_000637"
     CDS             767..1495
                     /gene="purC"
                     /locus_tag="ACF3MF_000637"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HFE3926662.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            1495..1749
                     /gene="purS"
                     /locus_tag="ACF3MF_000638"
     CDS             1495..1749
                     /gene="purS"
                     /locus_tag="ACF3MF_000638"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HFE3926663.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            1751..2422
                     /gene="purQ"
                     /locus_tag="ACF3MF_000639"
     CDS             1751..2422
                     /gene="purQ"
                     /locus_tag="ACF3MF_000639"
                     /EC_number="3.5.1.2"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HFE3926664.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            2423..4645
                     /gene="purL"
                     /locus_tag="ACF3MF_000640"
     CDS             2423..4645
                     /gene="purL"
                     /locus_tag="ACF3MF_000640"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HFE3926665.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            4630..6069
                     /gene="purF"
                     /locus_tag="ACF3MF_000641"
     CDS             4630..6069
                     /gene="purF"
                     /locus_tag="ACF3MF_000641"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HFE3926666.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            6092..7144
                     /gene="purM"
                     /locus_tag="ACF3MF_000642"
     CDS             6092..7144
                     /gene="purM"
                     /locus_tag="ACF3MF_000642"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HFE3926667.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            7141..7719
                     /gene="purN"
                     /locus_tag="ACF3MF_000643"
     CDS             7141..7719
                     /gene="purN"
                     /locus_tag="ACF3MF_000643"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HFE3926668.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            7716..9251
                     /gene="purH"
                     /locus_tag="ACF3MF_000644"
     CDS             7716..9251
                     /gene="purH"
                     /locus_tag="ACF3MF_000644"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HFE3926669.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            9267..10541
                     /gene="purD"
                     /locus_tag="ACF3MF_000645"
     CDS             9267..10541
                     /gene="purD"
                     /locus_tag="ACF3MF_000645"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HFE3926670.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            10663..11577
                     /locus_tag="ACF3MF_000646"
     CDS             10663..11577
                     /locus_tag="ACF3MF_000646"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HFE3926671.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(11710..13275)
                     /locus_tag="ACF3MF_000647"
     CDS             complement(11710..13275)
                     /locus_tag="ACF3MF_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3926672.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(13268..14719)
                     /locus_tag="ACF3MF_000648"
     CDS             complement(13268..14719)
                     /locus_tag="ACF3MF_000648"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFE3926673.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(14733..15749)
                     /locus_tag="ACF3MF_000649"
     CDS             complement(14733..15749)
                     /locus_tag="ACF3MF_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFE3926674.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            15969..17057
                     /gene="chvE"
                     /locus_tag="ACF3MF_000650"
     CDS             15969..17057
                     /gene="chvE"
                     /locus_tag="ACF3MF_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     substrate-binding protein"
                     /protein_id="HFE3926675.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            17111..18637
                     /gene="mmsA"
                     /locus_tag="ACF3MF_000651"
     CDS             17111..18637
                     /gene="mmsA"
                     /locus_tag="ACF3MF_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     ATP-binding protein"
                     /protein_id="HFE3926676.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            18639..19844
                     /gene="mmsB"
                     /locus_tag="ACF3MF_000652"
     CDS             18639..19844
                     /gene="mmsB"
                     /locus_tag="ACF3MF_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     permease"
                     /protein_id="HFE3926677.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            20101..21078
                     /gene="guaC"
                     /locus_tag="ACF3MF_000653"
     CDS             20101..21078
                     /gene="guaC"
                     /locus_tag="ACF3MF_000653"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HFE3926678.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            21342..22766
                     /locus_tag="ACF3MF_000654"
     CDS             21342..22766
                     /locus_tag="ACF3MF_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFE3926679.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            complement(22808..23065)
                     /locus_tag="ACF3MF_000655"
     CDS             complement(22808..23065)
                     /locus_tag="ACF3MF_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926680.1"
                     /translation="MPIRILTALVNKITIRKAFYISSAFFLFSNQTYNHLFLFKNVGV
                     IQFCCKHLFYLHIVNGRTNNGFFLVSLYRILFPKKKKQLEI"
     gene            23227..24336
                     /gene="pdhA"
                     /locus_tag="ACF3MF_000656"
     CDS             23227..24336
                     /gene="pdhA"
                     /locus_tag="ACF3MF_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0004739 - pyruvate dehydrogenase
                     (acetyl-transferring) activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HFE3926681.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            24339..25316
                     /locus_tag="ACF3MF_000657"
     CDS             24339..25316
                     /locus_tag="ACF3MF_000657"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HFE3926682.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            25341..26984
                     /locus_tag="ACF3MF_000658"
     CDS             25341..26984
                     /locus_tag="ACF3MF_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HFE3926683.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            26992..28398
                     /gene="lpdA"
                     /locus_tag="ACF3MF_000659"
     CDS             26992..28398
                     /gene="lpdA"
                     /locus_tag="ACF3MF_000659"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HFE3926684.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            28560..28820
                     /locus_tag="ACF3MF_000660"
     CDS             28560..28820
                     /locus_tag="ACF3MF_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HFE3926685.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKIQTKL"
     gene            28840..29607
                     /locus_tag="ACF3MF_000661"
     CDS             28840..29607
                     /locus_tag="ACF3MF_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HFE3926686.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            29775..31604
                     /gene="typA"
                     /locus_tag="ACF3MF_000662"
     CDS             29775..31604
                     /gene="typA"
                     /locus_tag="ACF3MF_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HFE3926687.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            31865..33637
                     /gene="recQ"
                     /locus_tag="ACF3MF_000663"
     CDS             31865..33637
                     /gene="recQ"
                     /locus_tag="ACF3MF_000663"
                     /EC_number="5.6.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HFE3926688.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            33751..34053
                     /locus_tag="ACF3MF_000664"
     CDS             33751..34053
                     /locus_tag="ACF3MF_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HFE3926689.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            34056..35219
                     /locus_tag="ACF3MF_000665"
     CDS             34056..35219
                     /locus_tag="ACF3MF_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFE3926690.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            35245..38673
                     /locus_tag="ACF3MF_000666"
     CDS             35245..38673
                     /locus_tag="ACF3MF_000666"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004736 - pyruvate carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009374 - biotin binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HFE3926691.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            38694..39818
                     /locus_tag="ACF3MF_000667"
     CDS             38694..39818
                     /locus_tag="ACF3MF_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP-associated domain-containing protein"
                     /protein_id="HFE3926692.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            39799..40245
                     /locus_tag="ACF3MF_000668"
     CDS             39799..40245
                     /locus_tag="ACF3MF_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFE3926693.1"
                     /translation="MIAVIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESA
                     KVCQLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQ
                     LQSLLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            40229..40567
                     /locus_tag="ACF3MF_000669"
     CDS             40229..40567
                     /locus_tag="ACF3MF_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HFE3926694.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            40686..41246
                     /gene="rsmD"
                     /locus_tag="ACF3MF_000670"
     CDS             40686..41246
                     /gene="rsmD"
                     /locus_tag="ACF3MF_000670"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HFE3926695.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            41243..41734
                     /gene="coaD"
                     /locus_tag="ACF3MF_000671"
     CDS             41243..41734
                     /gene="coaD"
                     /locus_tag="ACF3MF_000671"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HFE3926696.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            41724..42767
                     /locus_tag="ACF3MF_000672"
     CDS             41724..42767
                     /locus_tag="ACF3MF_000672"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HFE3926697.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            42926..43654
                     /locus_tag="ACF3MF_000673"
     CDS             42926..43654
                     /locus_tag="ACF3MF_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HFE3926698.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            43770..44015
                     /locus_tag="ACF3MF_000674"
     CDS             43770..44015
                     /locus_tag="ACF3MF_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFE3926699.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            44012..44230
                     /locus_tag="ACF3MF_000675"
     CDS             44012..44230
                     /locus_tag="ACF3MF_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HFE3926700.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            44366..44905
                     /locus_tag="ACF3MF_000676"
     CDS             44366..44905
                     /locus_tag="ACF3MF_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HFE3926701.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            44898..47171
                     /locus_tag="ACF3MF_000677"
     CDS             44898..47171
                     /locus_tag="ACF3MF_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HFE3926702.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            47209..48255
                     /gene="holA"
                     /locus_tag="ACF3MF_000678"
     CDS             47209..48255
                     /gene="holA"
                     /locus_tag="ACF3MF_000678"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HFE3926703.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(48344..48598)
                     /gene="rpsT"
                     /locus_tag="ACF3MF_000679"
     CDS             complement(48344..48598)
                     /gene="rpsT"
                     /locus_tag="ACF3MF_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HFE3926704.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(48998..49267)
                     /locus_tag="ACF3MF_000680"
     CDS             complement(48998..49267)
                     /locus_tag="ACF3MF_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926705.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(49529..49657)
                     /locus_tag="ACF3MF_000681"
     CDS             complement(49529..49657)
                     /locus_tag="ACF3MF_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926706.1"
                     /translation="MFEKLKYFIGTIGWFLLAVLLILGLAYLLFPDLIQNVFDTAF"
     gene            complement(49737..50192)
                     /locus_tag="ACF3MF_000682"
     CDS             complement(49737..50192)
                     /locus_tag="ACF3MF_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HFE3926707.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(50330..52258)
                     /locus_tag="ACF3MF_000683"
     CDS             complement(50330..52258)
                     /locus_tag="ACF3MF_000683"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFE3926708.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(52455..53288)
                     /locus_tag="ACF3MF_000684"
     CDS             complement(52455..53288)
                     /locus_tag="ACF3MF_000684"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HFE3926709.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(53480..54184)
                     /locus_tag="ACF3MF_000685"
     CDS             complement(53480..54184)
                     /locus_tag="ACF3MF_000685"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFE3926710.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(54207..54833)
                     /locus_tag="ACF3MF_000686"
     CDS             complement(54207..54833)
                     /locus_tag="ACF3MF_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFE3926711.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            55159..57534
                     /locus_tag="ACF3MF_000687"
     CDS             55159..57534
                     /locus_tag="ACF3MF_000687"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HFE3926712.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(57558..58049)
                     /locus_tag="ACF3MF_000688"
     CDS             complement(57558..58049)
                     /locus_tag="ACF3MF_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HFE3926713.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            58236..59156
                     /locus_tag="ACF3MF_000689"
     CDS             58236..59156
                     /locus_tag="ACF3MF_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFE3926714.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            59310..59654
                     /locus_tag="ACF3MF_000690"
     CDS             59310..59654
                     /locus_tag="ACF3MF_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HFE3926715.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(59844..60344)
                     /locus_tag="ACF3MF_000691"
     CDS             complement(59844..60344)
                     /locus_tag="ACF3MF_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFE3926716.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            60872..60955
                     /locus_tag="ACF3MF_000692"
     tRNA            60872..60955
                     /locus_tag="ACF3MF_000692"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:60906..60908,aa:Leu,seq:cag)
     gene            complement(61279..>61713)
                     /locus_tag="ACF3MF_000693"
     CDS             complement(61279..>61713)
                     /locus_tag="ACF3MF_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HFE3926717.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT        20243 a        10663 c        13216 g        17591 t
ORIGIN      
        1 accaaaaaag aagcagatcc gttagcggtt ctgcttcttt tagtttatta tattttctta
       61 tcaataatag gaacctgatt ttaaaagcgg ctacctcttt accgtgcctc tttacataca
      121 aaaaatagag gaattaagcg taaatggctt ggctattata actaaaatgc tggttatgga
      181 gatgttgcag caagttttcg agaaaagcgt attccatctc ttgtccattg aataagatct
      241 ggatacgata atgatttttg aaacgcttct gttcatgaat ctgactgatt gaaagttcgc
      301 ctttgtgttc tgtctgataa agaaaagtcc ttttacggca ttcagcacag cgcttggttg
      361 ctcggcggat ttttcggaat gtataaaaac tagtatcttt attgcataaa taaacgtctt
      421 tgatcgacag caaatcatta tatagacagg aacgttcttc agctgttaat tctgataaaa
      481 aaagctgacc ttgttttatt gcatcttcca tcggcaagtg cctcctcgaa cccattatcc
      541 aaatttttag ttaattctaa tataccatca ttaagtataa atgtaaacgc ttgttgatgg
      601 tataagattt tcgtttctga taaaacacga acattaaaag aatctaatgc cttaaatgta
      661 catatttttg ttgatttata aaaagatgat tgctaaaatt taaagtgaaa aaacgaacaa
      721 aaaacgatgt atttgctttt aatgtaaata aaaaggagag acgtacatgg agaagaaaga
      781 acttttgtat gaaggaaaag ccaaaaaaat atatcttact tctgatgaga acttgatttg
      841 gatagaatat ttagatcaag caactgcgtt gaatggcgcg aggaaagacc agataagtgg
      901 aaaaggagaa ttgaataatc aaatcacaag tgcaattttc cgttatctga ctcaaagagg
      961 aataaaaaat cattttattg aacaattgtc taaaaccgaa caattagcaa aaaaagtaca
     1021 aattatccct ctggaagtgg ttatccgaaa tattgcagca ggaagtttct caaaacgtct
     1081 aggtgttccc gaaggtaaag aattcatcaa accaatcatt gaattctact ataaggatga
     1141 ccagttggat gatccattta tcaatgaaga gcatatctat ttcttacaac ttgcaaagcc
     1201 ggaagaaatc agtgagctga aagcccaagc gttggctatt aatgaaattt tgaccgaatt
     1261 atttgctaag gtcggtttgg ttttagtaga tttcaagcta gaatttggcc ggtcgaatgg
     1321 acaaattttg cttgcggatg aagtaacacc ggatacttgc cgattatggg atgaacgtac
     1381 gaatgaacat atggacaaag acgtttaccg cagagatcta ggtgatttga tcccagtcta
     1441 tcaagaagta tataaccgtc tatcggaact aactgaagaa aaggagcgag tatgatgtat
     1501 ttcgtaaaag tatatgtaac ctataaagat tcagtgttag atcctcaagg ggaggcagta
     1561 aaaaaagcag tccatcgtat gggatatgaa acaatcgaag atatccgaat aggaaaatac
     1621 tttgagatac aacttgctga tgcagaagaa ccaatcgata cagtgattga aacgatttgt
     1681 gacaagctgc ttgcaaatgt aaatatggaa acataccgat atgaaatcaa aaaaatggag
     1741 gaagtataac atgaaatttg cggtcatcgt ttttccaggt tcaaattgtg acgcagatat
     1801 gttatgggca gttcgcgaga tcatgggcgc tgatgccgaa tttgtacggc atgatgagtc
     1861 ctctttagaa ggatttgatg gggttttact gccgggagga ttctcctatg gtgactattt
     1921 gagatgcggt gcgattgctc ggttttctac aatcatggaa gaagtgattc gttttgctga
     1981 agaagggaaa ccagtattcg gtacatgcaa tggattccag atattgacag aagcaggact
     2041 tttgccaggt gtactgagac gaaatgagtc tttgcatttt atttgcaaaa ctgtaccatt
     2101 gaaagtcaac cccaagacgg cctttacttc agagtatgaa gccgacgaaa taatctatct
     2161 tccagttgct catggggaag gaaattattt ctgtgacgaa gaaacacttc aagaactaaa
     2221 aaaaaataat cagattgcct ttacttataa tgacaacatc aacggcagcg tggaaaacat
     2281 tgcagggatt acgaacaaag cagggaatgt gttaggaatg atgcctcatc cagaacgtgc
     2341 agtagaagac ttgctaggat cagaagatgg gaaacggttc tttgcttcca ttttaaaaaa
     2401 cttcggaaag gtgaccgtat agatgaaaac attgaaagaa ccgacagctg aagagatcaa
     2461 gaaaaaaaga atctatgccg aatggggatt gactgatgaa gaatatcgaa tgatcgaaga
     2521 agatatctta ggaagaatgc ctaattatac ggaaactgga ctgttttctg ttatgtggag
     2581 cgaacattgt tcctataaaa attctaaacc ggttctacgc aaatttccta ctagtggacc
     2641 tcatgtgttg caaggccctg gagaaggcgc aggcatcgtc gacatcggtg atggactagc
     2701 agttgtcttc aaagcagaaa gtcacaatca tccttcagcc gtggagcctt atgaaggagc
     2761 tgcgacagga gttggcggaa tcatcagaga tattttcagc atgggggctc gtccaattgc
     2821 gttgctagat tcattgaggt tcggcgaatt agataatcca agaacgaaat atttactaga
     2881 agaagtagtt gcaggtatcg gcggatacgg caattgtatc ggcataccga ctgtaggcgg
     2941 cgaaattgca tttgatcctt gttatgaagg aaacccatta gtcaatgcaa tgtgcgtagg
     3001 tttgattgaa cacaaacata tccagaaagg gcaagccgct ggcgtcggta attcgatcat
     3061 gtatgtaggt gcaaaaacag gtcgcgacgg tatccacgga gcaacttttg cctcagaaga
     3121 atttaatcaa gaagaagaac agcaacgttc tgctgtacaa gtaggcgatc cttttatgga
     3181 aaagctgctg cttgaagcgt gtttggaatt aatcttgcat cattcggatt ctctaatagg
     3241 tatacaggat atgggagcag caggacttgt ttcatctagt gcggaaatgg cttcaaaagc
     3301 tggctcagga cttatattga cattagatga agtcccacaa agagaaactg ggatgacacc
     3361 ttatgaaatg atgttatcgg aatcacaaga acggatgttg atttgtgtta aatcaggaga
     3421 ggaagaaaaa atccaagaac tatttcagaa gtatgatcta gatgcagtca ctatcggtaa
     3481 agtaacagac gacgggcaat atcggctata tcatcaagga gaagaagtag caaatctgcc
     3541 agtcgatgca ttagctgaag atgcaccagt ttatcataaa gaaatgaaag aaccagctcg
     3601 aatcgtagaa tttcagcagt tagctcctta tcagccagtt atcgaagaac ctggacaagt
     3661 attgcttgat ctgctgcagc aaccgacgat tgcttcaaaa cgttcaatct acgaaactta
     3721 tgattcacaa gtacaaacca atacagttgt ccgtccagga agcgatgctg ctgtgatgag
     3781 ggttagaggg acgaataaag cgttagctat gaccacagac tgcaacgcgc gctatctgta
     3841 tttggatcca aaaatcggag gacaaatagc agtggcagaa gctgctagaa atattattgc
     3901 tagcggtggt aagcccttgg cgatcaccga ctgcctgaac tatggttctc ctgataaacc
     3961 agaagttttt tgggaattat cgacttcagc tgacggaatt gctgctgcgt gtgaaacgtt
     4021 aggaactcct gttatttcag gaaatgtctc tttatataat gaaacggatg gtcaagcaat
     4081 ctatccaaca ccaatgattg gtatggtcgg attgattgag gatcataaac atatcactac
     4141 tcaggaattc aaaaaatcag gggatctaat ctatatatta ggtaagacgt ttgcagattt
     4201 tgatggcagt gaattacaaa agatgcagct tggaagaatc gaaggtgtga tccgaaactt
     4261 tgatctatcc attgaaaaga gaaaccaaga gttagtattg acagccatcc aaaacggatt
     4321 gattgaaagt gctcatgact gttcagaagg tggcttggca attgcactgg cagaatcagc
     4381 tttcaaacat cagctaggga tatctgtaca gtttgaattg tcctctgctc aattatttgc
     4441 agaaactcaa tcaagatttg tgttgacagt cgcaccggaa aataagacac gattcgaaga
     4501 aatgatggga gatgctgctg ttttagcagg taaggtgacg gatgaagcga taatcgaaat
     4561 ttcagcaact gacggtcaga tcaaaataga aactgcagta gcaagaaagt gctgggagga
     4621 tgcaatcgta tgtcttatga agtgaagagt ttaaatgaag aatgcgggat cttcggtgtt
     4681 tggggtcatc cagacgccgc tagtgtggca tacttcgggc tccatagtct tcagcatcga
     4741 ggacaagaag gtgcaggtat cgtgtccaat gatcgaggaa agcttaaggg gcatcgagat
     4801 ttggggctgc tttctgaggt attcaaagat caaagaaaat tgcagcagtt aacaggagaa
     4861 gctgcaatcg gacatgtacg ttatgcaaca gcaggcaatg gaagtgtgga caatattcag
     4921 ccttttctat tcaaatttca tgatcagtcg atcggcttag cgcataatgg taacttgatc
     4981 aatgctcgtt cccttagaaa agagttagag gaaaatgggg cgatcttcca ttctaactcc
     5041 gatacggaga tattgatgca tttgatccga cgaagtgaag aaacagattt tttaaataaa
     5101 ttaaaaagtg ctttgaatga agtcaaaggt ggctttgcct atttattaat gacagaaacg
     5161 gcaatgattg ccgctttgga cccaaatggt tttcgtccat tagcaatcgg acaaatgaaa
     5221 aacggagcat acgtgattgc ctcggaaact tgtgcattag aagttattgg ggcacgtttt
     5281 ataagagatg tccagcctgg tgagatagtg atcatcaatg acgaaggaat ccagattgat
     5341 tgctttacga aggacacgca gctttctatt tgttcgatgg aatatatcta ttttgccaga
     5401 ccagattcaa acatcgcagg gatcaatgtg catactgcac ggaaaaatat gggacggaat
     5461 ttagcgaaag aatcgccagt aaaagcagat atggtcgttg gcgtacctaa ttcttctttg
     5521 tcagccgcaa gcggttatgc ggaagctagt ggaatccctt atgaaatcgg attagtaaaa
     5581 aatcaataca ttgcccgaac atttatccag ccaacgcctg agctaagaga gcaaggtgtt
     5641 cgaatgaaat tatctgctgt acgaggagta gtggaaggta aaaaggtgat tatggtcgat
     5701 gattcaattg ttcggggtac gacaagcaga cggatcgtcc atcttttgaa agaagcaggg
     5761 gcaaaagaag tccatgtgag gattgcttct cctcctttga aatatccatg tttttacggg
     5821 attgatattc aaacgcgtaa agaactcatt gcggcaaatc acacgattga tgaaatcaaa
     5881 gaatgtatcg gtgcagattc tttaggtttt ttaagtgaag agggtctgat cgaatcgatc
     5941 ggtctggaaa aagatgctcc gtattcagga ttgtgtatgg cttatttcaa cggagattat
     6001 ccgacgccgt tatatgacta tgaagaaaaa tatcaggaat cactaaaaga aaaagtatcg
     6061 ttcttttaaa agcagaccaa gaagggagta tatgaattca atggcaaatg catacgcaaa
     6121 agctggcgta gatgtcgaag ctggatatga agtagtagaa cggatcaaga agcatgtcaa
     6181 aaaaacggaa cgtttaggta tgatgggcgc tataggagga ttcggcggtt gttttgattt
     6241 atcggtcttt caattaaaag agccagtcct tgtctcgggg accgatggcg tggggacgaa
     6301 attagcagtg gcaatcgaag cagacaaaca cgatacaatc gggatcgact gcgtagcgat
     6361 gtgtgtcaat gatatcttag cacaaggcgc agagccgtta tatttcttag actacttagc
     6421 aacggggaaa aatgatccgt tacgtttgga aaatgtagta aaaggtgtag cagatggatg
     6481 tgttcaagga aatatggcgc tgattggcgg agaaacagct gaaatgcctg gtatgtactc
     6541 aggtaatgat tatgatctag ccggatttgc tgtagggata gctgaaaaat ctcaattatt
     6601 gacaggagaa acgatcaacc caggagatgt gttgcttgga atagcatcta gcgggattca
     6661 ttcaaatggg tactctcttg ttcgcaaaat tttctttgag cagcagcagt tttctttatc
     6721 atcaaaactg ccagaattga aaaaaacact tggcgaagaa ttgcttgagc caacgaaaat
     6781 ctatgtttct tccttgcttc cgctgatcaa agaaaagaaa ataaaaggag ctgcacatat
     6841 cactggtgga gggtttgtag aaaatatccc gcgaatgtta ccagaatcta tggctgcaca
     6901 aatcaaactt ggctcatggc cgattcttcc aatattcggc tgtttacaaa aatatggtga
     6961 aattcctgag atggagatgt atgaaatctt caatatgggc atcggtatgg tcctggcagt
     7021 cgaagaatcg aaagtaaaag aaatagtaca cgaaattgag caagctggcg aaaaagttta
     7081 tgaaatcggg aaagtgatcg ccaaagaaaa acatcgtgtg gtgtttatag gagaagaacg
     7141 atgagaatcg ctgtttttgc ttctggaaac ggaagcaact ttcaagcgct agccgattat
     7201 ctatcgaaaa aaggattgga atcttcgatt gactggttgt tttgtgatca gcctgaagca
     7261 tatgttttga aacgtgcaac tgcgttgagt gtaccggcag attgtttttc acctaaagaa
     7321 tttgattcaa aaaaagagta tgaagaagca attttgcata aattgaaaga aaaaaagatc
     7381 gatttgatcg tattagctgg atatatgcga atcattggac cggtattgct gaaaaattat
     7441 gataaaagaa tcatcaatat ccatccgtct cttttacctg ccttccctgg tttgcatggc
     7501 atacgtgatg cctttgaagc tggagtaaaa gaaacgggtg tcacaattca ttatatcgac
     7561 caaggtgtag atactggacc aatcatccgg caggaaaaag tgagaattga acaggaggac
     7621 acgttcgatt ctttagaaga aaaaatccat agagtagagc atcgaatcta tccagaagtg
     7681 attagtgaaa ttattgaaaa tggaggctat ctgaaatgac aagagcattg atcagtgtat
     7741 cagataaaac tgggattgta gcattcgccc aaggtttgat tgaacaagga gtagaaatca
     7801 tttcaacagg aggaacaaag catgcgttgg ataaagctgg gatcaaaacg ctttcgatcg
     7861 aagaagtgac agggtttcct gaaatgatgg atggccgtgt caaaacactt catcctaaaa
     7921 tccatggtgg tcttttagga agacgcgatc tccctagcca tatggaggca atggaaacgg
     7981 aaaatatcca accaatcgac tttgtttgtg tcaatttata tcctttcaaa gaaacgatta
     8041 tgaaaccaga tgtcgaaata gcagaagcta ttgaaaacat tgatatcggt ggtcctagta
     8101 tgctccgtag tgcagcaaaa aaccatgaat ttgtcacctc tgttgttgat ccatctgact
     8161 atgaagaagt actttcagaa ttacgtcagt atgggcatac ttcactttct ttcagacaaa
     8221 aactagcggc aaaagtcttt cgtcatactg cggcatatga tgcactgatc gctcaatact
     8281 taacggattg ggtggaagaa aaagaaccgg aaaaattgac acttacgtat gaacgaaaac
     8341 aaacgcttcg ttacggtgaa aatagccatc aagccgctgc cttttatcag tccgctcttc
     8401 tggaaaaata ttcgatcgca gcagcaaaac aactccatgg gaaagaactt tcttataata
     8461 atatccgaga tgcagatgct gcgctacgga tcatgaagga atatgacgag ccaacggtag
     8521 tcgccttgaa acacatgaat ccttgtggta ttgggacagc atctacgatt ttagaagcgt
     8581 gggaagcagc gtatgaagca gatcctgttt caatctttgg tgggatcatc gttttgaatc
     8641 gagaagtaga tctgccaaca gcagaacaga tgcataagct gtttctagaa atcatcattg
     8701 ccccttctta tacacaagaa gctttggaat tactgcaaaa aaagaaaaac atccgattac
     8761 tgacagtaga ctttgcgcag gaagaaaatc aaaatcgaga agaaacggtc tcagtcttag
     8821 gtggacttct tgtacaagat caagatctgg caatagaaaa tgaagaagag tggaaagtcg
     8881 tgacaaaacg taagccgact ccagcagaag caaaagcatt agcgtttgct tggagagctg
     8941 tcaaacatgt gaaatctaat gcgatcgtac tggcaaacga acgtcagaca gtaggaatcg
     9001 gagccgggca gatgaatcga gtcggttcag taaaaattgc gattgaacaa gcgcaagaga
     9061 aaatggaagg tgcagtttta gctagcgatg cttattttcc aatggatgat tcggttgaat
     9121 atgcagccaa acatggtata aaagcaatca ttcagccagg aggaagcatc aaagaccaag
     9181 attctattga tatggcgaat aaatacgatc tagcaatggt ctttactgat gttcggcatt
     9241 ttagacatta gagaggagtc ggataaatga acattttggt gatcggtgca ggtggtcgtg
     9301 aacatgcaat aagtaaaaaa cttttagcca gtccgaaggt ggatacggtg tattgtgcgc
     9361 caggaaatcc ggggatgaca aaagatggta tcaattgtgt cgctatcagt gagcgagatc
     9421 attcagcgtt aatccatttt gttaagaaag aggctattga ttggagtatc gttggtcctg
     9481 aagttccttt gttaaatggg atcgtcgatg attttatggc ggaaggattg aaaatcttcg
     9541 gtccgacaaa agcagcagct ctgatcgaag gttcgaaaag ttttgctaaa caattaatgg
     9601 atacttatca aatcccgaca gctaaatcca gaagttttga atgttacgaa aaagcagcag
     9661 cgtatatcaa agaaaatggt gcgccaatcg tagtgaaagc ggacggctta gcagctggga
     9721 aaggtgtagt cgtggctacc acagtgaagg aagcgctgga tgcggcagaa caaatgttga
     9781 accagcatcg atttggggat agtagcaaaa aaatcgtcgt agaagagttt ttggcaggag
     9841 aagaattctc ccttttggcg tttgtccgta ataccaaggt gtatccgatg gtcatttcgc
     9901 aagatcataa gcgggcattt gataacgata aagggccaaa tacaggcgga atgggtgctt
     9961 attcaccagt accgcaaatt tcaaaaaaga tgattgaaaa agctgtggaa gaagttttaa
    10021 aaccagcggc tttgggaatg aaagaactag gacgctcttt cacgggtgtt ttatatgcgg
    10081 gtttgattgc tacgaaggaa ggaccaaaag tgatcgaatt caatgcgcgt ttcggtgatc
    10141 ctgaaacgca agtcgttctt tctcggttga agagtgactt tgcgcaagta atcgatgatt
    10201 tattagagaa tcgtacagta gagttaaagt ggcagcaaga aggatacaat gtaggcgttg
    10261 tggttgcagc tgccggttac cccgaagaat atgagacagg aatggttcta ccagattttc
    10321 tggaagaaga gctttctgtt tactatgctg gagtttcctc aaataacggc aaactagttg
    10381 gagcaggagg acgtctttat ttagtagaag catacggtga gacgatcaaa gaagcacaga
    10441 aaaaaattta caccgcgtta atggataaaa cgacagatgg aacattttat cgtacagata
    10501 ttggagaaaa agctgccaat agcgaactga tcgtgaagta aatcagctgc ttccatttat
    10561 aaaaaataca acaaacataa tcggaagcgc cgattttagt gaagcctttt cataaagagt
    10621 gtggtacact tttgttgtgt atataaataa ggaggagttc agatgaaaaa aattcaatta
    10681 ggtacttctg atcagaaagc agctgcagtg atcttaggct gtatgcgtat caacaatgcg
    10741 gaagatccag taaaagtgat tgagacagct tatgaaaacg gcattgattt ttttgaccat
    10801 gcagatattt atggaaacgg tgaatgtgaa gaaatctttg cagatgctct agcaaaaaca
    10861 tcaatcaaac gagaagatct ttttattcaa acaaaatgtg gaatcgttcc aggtgtgatg
    10921 tttgattttt ctaaaaaaca tatcattgaa tctgtagaaa aaagtttgac ccgtctgaaa
    10981 atggattatg tggatgcttt acttcttcat cgtccagata cattggtaga accagaggaa
    11041 gtagctgaag cgtttgatga attggaacgg tcaggaaaag ttcgttattt tggcgtcagc
    11101 aatcaaaaac caatgcaaat cgaattgctg aaaaaatatg ttcgtcaacc attagtagct
    11161 aatcagctgc aatttggctt gaaacatact ggaatgatcg atcaagggat tcatgtcaat
    11221 atgacagatg aagcaagtat cgatcatgac ggtagtgtac ttgattattc ccgattgcat
    11281 gatatgacga tccaagcatg gtcaccatac cagtatggat tttttgaagg tgtatttatc
    11341 gggaacgaaa aattccctga attaaaccaa acattagaag aactagcagc taaatatcaa
    11401 acgacaccaa ctggcttggc ttctgcttgg attttacgcc atccagccaa tatgcaagtg
    11461 atcgccggta cgatgaacgt agggcgaatc aaggaaatcg ctcaagcttc agaaattaat
    11521 atgtctcggg aagattggta cgaattgtac cgtgctgctg gaaacatttt accttaaaga
    11581 ttgtcataag caggtcaaaa gggctataaa ttaaaaagac agaataactt gaaagctgtt
    11641 ttcagcttcg agatattctg tcttttttta ttgcaaatgg aaagagtatc attgtacgga
    11701 tttcgtttat tagttatttt tgtttttaag gaaaagctgt gtccgatatt cttttggaga
    11761 aatcccttgt tttttcttaa ataaataact gaaatagtta gggtcattat aaccaatttc
    11821 aaaagcaata tctgaaatac gatagtctga ttgctgcaat aatttttttg ctaattcgat
    11881 tctttgttct gtcagataat cgatgaatgt ttggttaaac gattgagaaa aaatcgtact
    11941 gaaatgagag ggacttaatg caacttgttg agcgacccaa gttaaggaca tatctggatc
    12001 ggtaaaattt tctttgataa aatccaatgc atggttcaaa attggctgat atttgttcct
    12061 tgaaggctgt gagggcagag cagttaagaa agaaatgaac atataaactg tcgaacggta
    12121 aagcgagtcg tcggcgctga ttgctaagcg ttgactggtg gatgtgcaat gaaccatttc
    12181 ttgcgggatt ttcttttctt tcaggcagac atgctggagt agcttagtca agacaaataa
    12241 acgatataat cgtgttcgag ttggtgtgcc ttgtggtttc gtcaagtgtt cgatgtactt
    12301 agatacttcg tttttcgata atgaagacaa atcaagtgag aggtcaaagt aaaagacaga
    12361 atcaactgga agtttcgctt cttgaatcaa atcctcatag ctgataattt gttctttaag
    12421 ggaactggcg gtttcaagta tcatctgcgt gatctcaaaa gatgcaggta attcgctgat
    12481 tctttctgcg acaggaccaa tggcgacaga aaaattattt ttttgtccct tttctaattc
    12541 atggaccaac gtttgggcta cctgataact ggtctcgatc acattttctt caagagaatc
    12601 aactattaaa aatttgatga atcgagagga aacagcagag aagatcactt gttgattctc
    12661 cctaaataaa aacttcaaat aatcactgag atgagcgtaa tcttcaaagt ctgtactgac
    12721 ttggtttgct gctaataata cggtcatttt tttccctgct aaagagcgat tgaaagattc
    12781 agcaagtttc aatgtttcac tgatcgtaag tgagcctttg aacaaaccgt tcaagaaatg
    12841 attttttttc aattcgaaaa caagatcaga agaagtgtgc gtttcttttt gctgcaaatc
    12901 taaagcagtt actgcttttt ctattgcttg tttcaattcg ctacttttaa tcggtttaag
    12961 cagataatca tctgcctgta cctggattgc tcctttcata taatcgaaat cgtcgaatcc
    13021 actaataaat atgagacgag tccaaggaag tagtttcctt gcttcttttg aaaaagtcaa
    13081 cccgtccatg aaaggcattt ggatatcagt cagaatgatg tcgggctgta agtcgataat
    13141 tgaagacagt gccatctcac catctccagc ttcgccgaca taagtgattg gataataaga
    13201 accaaggaca gttatttgtt cccgcaagtt attgcgaatg aggtattcgt cttcgatgat
    13261 aaaaacttta tacatgtttg tttcctccaa ttgttttggg agatagaggg atcatcagtg
    13321 tgacagttgt tccttctcgg tatttgctgt caatcgtgat aggtttttga tcatttccgt
    13381 aataaagaag gagacgcttg tttacgttgt aaagtccgta gccgatactg aaatctgaat
    13441 cgatcccttt ggctaactct ttacgtattt ctgccagttt ttctgcaggg atgccaatcc
    13501 cgttgtctat aactttgaat tggatcatct catcaatttt gcatgtggta atacgaataa
    13561 atcctttgtg acggacgtac ttcgttccat ggtatacagc attttcaatc aatggctgca
    13621 agatcatttt taaaatagaa acaggaaaaa gtgtttctgg tatatcgatc ttatagtcaa
    13681 gcatatggcc gtatcttatt tttaagatga ctagataatc attgatatgg ctaatttctt
    13741 tttcaagagg aatccagtct tgtcctttgc ttaaagacgt acgaaaaaag ccggaaagtg
    13801 catgggtcat agtcagagct tcttcaaagc agtcttgttc gatcaaagaa ataatggcat
    13861 ccaaactgtt ataaataaaa tggggagtaa tctgagcttg caatacacga acttcacttt
    13921 gtgctaaatg gtattgtttc aaagcgttct cccgtaaaga ctggtttaga tcttccgcca
    13981 ttttattcat gctagcggta agtgtttgta attccagtgt ttccggcagg gttaaacgaa
    14041 agccaaggtt ccctgaagaa agttgttctg acatctcgat cagctgattg atcggttctt
    14101 ggacctttct ctctaaaaag cgacgattct ttttcgcata gaaaaaaatg gtactaagaa
    14161 ctccaagttc cactattgtt aatagaatga gcgagcggac aagtgtcgta ttttttttgc
    14221 ttgctaagtc gatctccaca cgaacaaaat cttgtaagat atctgacagc agttgagtga
    14281 cagaatctac ctgattgatg atctcttcat tggtatccat aaaatctttt gccaagatat
    14341 tattgatcag ctcgttttga taatcttcca gtgtatcgat cgtacgtagc gatacatcta
    14401 acgtactaat ttctttaagt gtatttgtat tatttttgat ctctcgaata tcattcctaa
    14461 gttcttctag gatattttcc tcattgaact catctacggt tacttggcca gaaatcaagt
    14521 cccacatact ttccaaaact ttttgatcaa ccttcaaagc aattgcatct gctttttgga
    14581 tatttgcgat cgtctgttga taaatcaaaa gctgttgcga atataacagt atgctcagta
    14641 gcaaagggat aacagcaaat agaagcatgg ctttgtttgc ttgggcaaaa atctgtttta
    14701 tgcttaaatt ttttgtcatg atacttctcc agtcaataat ttctggttgg gatgttagct
    14761 atattctgct gggaaaagac agtctcggaa ataaaaatat ctttaggtaa tgtttttcct
    14821 gtttgaatat ttccaaaata acgagtaacg gtattggcta cataccagcc gacatcaggt
    14881 ttacactcga ctacacaatt gacgattcct gagcgtagct tctcgatcat atcttcttgt
    14941 ccatcaatag ttacaatgat caaatcttct ccaggtttga ttgatgtttc ttttatcgca
    15001 gctaaagcac cgtgagtcat ttcatcacta tggctgtata atacatcgat ttcggataaa
    15061 tcatttgttt ctaaatatcg tttcatctgg tcttttcctt tcatccgaat aaaatcaccg
    15121 acaattcggt gaacaatagt catcggaggt ttatggtcga tggttccatc tttttttagg
    15181 gttggtttac gattgattga ttccaaaaat ccttcggagc gtagcttggt cggtgtggag
    15241 ttctctgaac cagcaagttc taggattctg atttcctgtt tctttgaatt tgtgaagtga
    15301 ttgctgacaa ataaacccgc ccgatttcct tctgctttga aactggggcc aatgtgggtg
    15361 acgaaaagct cgggatcatt cgtttgaata tgtctgtcga caagtatgac agggatccct
    15421 gctcgctttg cttcttttaa tacagagtcc cacccggatt cttgcaaagg agtaaaaatg
    15481 atcatatcca ctttataggc aatgaacgtc cgtatatctt ggatttgccg ttcctgattc
    15541 atgtagccat ttcggtagag aacttggtaa tcttcttttt caagcgcagt gataattgat
    15601 tcagtatgct ttttccgcca gctactctcc gttcctgatt gcgaaaaacc aacgactagt
    15661 gggtcaggtg cttcctttgt attaggtgta caccccatca tttggtaagc gattacaaca
    15721 agggctaaaa aaaataaaac acgtttcact ttaaatcact ccatctggat ttgttagtac
    15781 tatcttatca gataaaaggg aaaatcaaag tcaaaaggaa tcaatcgaaa aaaatccaag
    15841 aaacttaaaa aaatccaaga caaaaaaagt acacctaaaa aatttaaagt aaatcccata
    15901 aaaaaatcaa tgttaacgct ttctttatta gctatactcg gtgtatcaat tgaaatgggg
    15961 gataaaaaat gaaaaacaaa tttagaaaga ttgttgggac tatcgctatt ttgaccgcaa
    16021 gcattctatt aagtgcgtgt ggcaattcag gatctgcaga tgatagtacg gggtatgtag
    16081 gaatcgctat gccgaccaaa tcagcagaaa gatggatcgc tgatgggaac aacatggtct
    16141 cggaattaga aaaactgggt tataaaacag atcttcaata tggagaagat aaagtagaaa
    16201 atcaagtagc acaaatagaa aatatgatta caaaaggggt agatacactt gtgattgctt
    16261 ctatcgatgg ttcggcttta actgatgtgt tagctaaagc aaaagaagca gatatcaagg
    16321 tgatcgccta tgatcgttta ctgatgaatt cagaaaatgt cgattattac gcgacttttg
    16381 ataattttgg agtaggtgta tcgcaagcag cttatattga agagcactta ggattgaaag
    16441 aaggaaaagg accattcacg attgaattat ttggtggctc gcctgacgac aacaacgcac
    16501 taatcaatta caacggagtg atgtctgttt tacaaccata tatggacaac ggtcagttgg
    16561 tcgtgccatc tggacagacg agtttcagtc aaatcgctac gcttcgctgg gatggttcta
    16621 cggcgcaagc aaggatggat aatctgttaa gcgcaaatta tactgaccaa acattggatg
    16681 ctgttttgtc gccatatgat ccaataagtt taggaatcat ttcgtcatta aaaggcgtgg
    16741 ggtatgggag tgaaagtaaa cctttacctg tgattactgg acaagatgcg acagttgctg
    16801 gcgttaaatc gatcattgcc ggggaacaaa cacaaacgat ctttaaagac acacgtatct
    16861 tagcaaaaaa tacgattgaa atgatcaaag caatcagtga tggagaagag gttccggtca
    16921 atgatactga aacttatgat aatggggtga aaactgtccc tacgtattta gcaaatacag
    16981 tatctgtcga taaagataat tatcaagcag agctgatcga caccgattat tataaagaat
    17041 ccgatctgaa aaattaagag gaaccaaaca aggaactaaa gagatctaag tcagagagag
    17101 gataagaatt atggcggatt gtattttaaa aatggcagat atcaccaaaa aattttctgg
    17161 aatccgagcg ttagattgcg tgaatctgat gattgaacgt ggggaaatcc atgcattgtg
    17221 cggagaaaac ggagcgggaa aatcaacatt gatgaatgtc ttgagcggct tgtatccata
    17281 tggctcctat gacggggaaa tcttttatga tggaaagctg tgtcaattta aagatttgaa
    17341 agatagtgaa gaaaaaggca tcgtcatcat tcatcaagaa ttagcactaa gtccttatct
    17401 ttcaataaaa gagaatattt ttctcggaaa tgaacaagca gaaagaggcg tgattgattg
    17461 ggaactgaca gaaaagaaaa catatgaact gctgaataaa gtcggtttgt ctatcgaccc
    17521 gaatcttcta gtatcccaga ttggcgtagg gcaacagcaa ctagttgaaa tagctaaagc
    17581 attatcaaaa tccgtccgtc tgttgatttt ggatgagcct accgctgcat tgaatgaaga
    17641 agaaagcgcg aatttgctga gattgatccg agagttgaaa gagcaaggtg taacctccat
    17701 cattatttca cataagctga atgaaatcgt ggatatcgca gatcgaatca ccattttacg
    17761 ggatggacag acgattgaga cactagaaaa tgaaatgatc agcgaagagc atattattcg
    17821 cggaatggtg ggcagagatt tagttgatcg ttatcctgaa agaaaaccgg atattggaga
    17881 agtttatttt aaagtagaag actggacggt ctatcaccct cttgatcacg agcgaatcat
    17941 aaacgaccac atcaacttgc atttgaaaaa aggagagatt gtaggaatag ctggactgat
    18001 gggagcgggc agaactgaat tcgctatgag tctatttgga cattcttatg gaagcaagat
    18061 atccggacgt atattaaagg aaggggcaga gatatcagtt aagaccgttc cttcagccat
    18121 tgcaaacgga ctcgcttatg tctcggagga ccgaaaatct ttaggactga atctgctgat
    18181 ggatattcgg gaaaacgtga cgctgagcag tttggataaa ataagtcaaa aaggagtatt
    18241 agataaagaa aaagaagtaa ctgaggcaga aaatttccgg aaaaagatgc gtataaaaac
    18301 aaactccatc catcaaattg tcagtagtct tagtggtggg aatcaacaaa aagtcgtttt
    18361 atccaagtgg ctgatgacac aacccgatat tctttttttg gatgagccaa cccgtgggat
    18421 agatgttggg gcaaaatatg agatctacac gattatcgaa gaaatggcag caaatggcaa
    18481 agctgtctgt cttatctctt ctgaacttcc tgaaatatta gggatgtgtg atcgaatcta
    18541 tacgatgaac gaaggacgta ttacaggaga agtctcgcga gaagatgcag atcaggaagt
    18601 cttgatgaaa ttaatgacga aagaagaggt gggttaagtt ggaacaggca aaaaatctta
    18661 cggataaaaa agagaaaaaa ctaaatttga aaagtagagc agctgatctt tttggtcgct
    18721 acagcatggt gatcatttta gcgggactac ttattgcgtt tcaattgatg acggatggta
    18781 ttttctggcg tccattgaat ataactaacc ttgttctgca aaatagccat atattagtac
    18841 tagctgcagg gatgttatta gttgtgctct taggtcatgt ggatttgtcg gtagggtcag
    18901 tgatggcgtt tgttggtgca attgcgggca tgatgatggt caatcgccaa atgaacccgt
    18961 ggatgacagt tatcgcatgt cttgcagtag gcgggctgat cggcgcatgg caaggttttt
    19021 gggtagctta tgcagggata ccggcgttta tcgtgacttt agcaggattg ctgatgtttc
    19081 gtggactgac acaagttgtt ctaggaggcc aatctctagc accttttcca gctgttttcc
    19141 aaaaaatgtc tacgggttat ttaccagact taagcgaagg aagcagcctt cacttcttga
    19201 cattgatttt aggaatgatc atcacgatcg tgttagttgt tggtcaatgg cgaacaagaa
    19261 atcgtcggaa aaatcattta tttgaagtgg aatctccaac agctttcttg gtaaaggcgg
    19321 tatttacagc agtcgttgta ctaggaataa cttatatctt tgcctcttat caagggtatc
    19381 cgattatttt gatcattctt ggtttgatcg ttgcagcata tgggtttttg acaaataaaa
    19441 cagtagcagg tcgacagatt tatgcgacgg gcggaaatcg aaaagcggct gaactatcag
    19501 ggatcaaaac aaagcgaatc acgttctggg tattcgtcaa catgggagtc atggcagctt
    19561 tagctggatt agttttagct gctcgattga atgcggcaac acctcaagca ggtacatcga
    19621 tggaactgga tgcaatggcg gcagtatatt ttggtggtgc ttcgacttcc ggcggcattg
    19681 gaacaatcat gggtgcgatt gtcggtggct tggtcatggg tgtattgaac aatggcatgt
    19741 cgattttagg cgtcggggta gactggcagc aggcaatcaa aggattgatc ttgcttttag
    19801 ccgttgtgct agacttgtat aataagaaaa aacgaacaac gtaggagaac gccggttatt
    19861 cagaaaaaag actgtgacaa gacatttgtc acagtctttt tttcgctaaa agcgaacatt
    19921 cattgtttcg tttgtataga ctaaaaataa tatatgtttt tttaccattc gtataaattc
    19981 tctttttgct cttgattttt ttgcttaatt gagttaaatt acatagggcg ctaaaaaaag
    20041 ccttgattaa attaataatg ttcgtgtttt gctggatgtg aacatcagga ggataatgta
    20101 atgaaagtat ttgattacga agatattcaa ttaattccta ataaatgtat cgtaaatagc
    20161 cgttctgaat gtgatacaac ggtcacatta ggtaaacata cattcaaaat gccagtagtg
    20221 cctgccaaca tgcagacgat tattgatgaa acaatcgcag aattcttagc ggaaaatggt
    20281 tatttctata tcatgcatcg gtttgatgaa gcagctcgaa ttccgtttat caaaaaaatg
    20341 aaaaagcgtg gattgattac ctcgatcagt gttggcgtca agaaagagga atattccttt
    20401 atagagaagt tggcagaaga atcgctaaat cctgattata tcactatcga catcgcgcat
    20461 ggacatgcta actcagttat tgatatgatt cagcatatta aaaaatattt gcctgaaact
    20521 tttgtgattg ccggtaatgt tggtacaccg gaagccgtcc gtgaattgga aaatgcgggc
    20581 gcagatgcaa caaaagtcgg gattggtcca ggaaaagtat gtattacaaa aatcaagaca
    20641 ggctttggga ctggaggctg gcaactggca gctcttagat ggtgtgcgaa agcagctcgc
    20701 aagccgatca tcgctgacgg tgggatcaga acacatggcg atattgcaaa atctgtccgt
    20761 tttggtgcga caatggtcat gattggttca ttgtttgccg gtcacgagga atctcctggc
    20821 gaaacaaaag tcgaaaatgg aatcgtgtat aaagaatact ttggttctgc ttcagaattc
    20881 caaaaaggcg aaaaacgaaa tgttgaagga aagaaaatct ggatccaaca caaaggatct
    20941 ttgaaagata cactagtgga aatgcaacaa gaccttcaat catctatttc ttatgctgga
    21001 ggaagagatc tggaagccat tcgaaaagtt gactatgtca tcgtgaaaaa ttcgattttt
    21061 aatggagaca caatctaaaa aataaataaa atattaggat gttgtgaaaa agttgtcctg
    21121 cattaagtaa taagaacagc caaacaaaaa tagttcttta tatgttttgt ttggctggaa
    21181 ttattatcgc agatacaagc ttttgaacat cattattcag aataagggac tgtgataaga
    21241 tttttgtcac agtcccttat gttttgcaaa aaaagttttt cttttttctc gtaaattcgg
    21301 taaaatcaaa agaaaaaata gacaatagaa aagagaagct tatgtgggaa aaagtagaga
    21361 aaaaacaagg accgatttat cgtcaaatta tggaacagat tatgagagaa atcgaaaacg
    21421 gaaggatcaa tcctggaagt caacttgaat cagaacgaaa actagggcaa ctttttggtg
    21481 tgaatcgttc caccgttgtc catgcattgg aagagcttag ggagcttggg gtactaacga
    21541 gcaaacgtgg cagcggatgg tttgttaatc agactgaatg ggggaaattc gctgttccaa
    21601 gaatcgattg gcggcaaatg atctctcctc gttatgagca gacggactgg tatgagcaaa
    21661 aaataagaga agcaaagcag atccaaaaaa catcgtttct tgatttatac gctagcgaga
    21721 tgccagatga gcttttgccg aattttgagt ttccttctta ttctcttgaa gaaatcttag
    21781 cggaagaaaa agaaatggat cttttaggct atactccgtt acgtaacaaa atcaaacggt
    21841 atttggaaag taaatttgaa ttggcatttt cccccaacca gcttcttgtg actggtggcg
    21901 gtcagcaagc aatctttttg attttacaaa cgattctttc agctggagag gggatagctg
    21961 tagagtcacc ttcttttttt taccgattac ctcttttcaa agcttcagga acgcgtttat
    22021 ttgggatacc gatggatgaa gaagggatcg acttagaaaa actgaaagaa tcgatccata
    22081 aaaataaatt gaaagcagtg cttatcaacc cgaattttca aaaccctaca ggaaaagtga
    22141 tgagtcaaaa acgacgagaa aagctagtag aattgtgtcg acagtatcgg cttccaatta
    22201 ttgaagacga tgtatttacg gatctttcat ttctaaacca agaagaagtc cttcctatac
    22261 gaacgattga tccggataat gtgttatacg tcggttcgtt atctagggtt ttaggaaaaa
    22321 caacgaaaat cggttgggtg ataggacctg agacttttat ctcgcaacta gctcaagcgc
    22381 aagaaatgat ggagttttcg atgaatatcc ttacacaaat cacagtggct aatgtattta
    22441 atgaagcaat tgatttgaaa atgcaagatg taagaaaaaa gttgaaagaa aaaagccgac
    22501 tgataagcgc ttggggagat tcacaatcgt ttttcaagct tcattcaatt ttaggtggtt
    22561 actatgcctg gattacttgg gatgggaaaa aactagaccc cgaactagca gaaaaagtag
    22621 tagatatggg tcttggaatt gcaccaagtc tactttttgg gcaagatata aatggaatca
    22681 gaatcaatta cagtaggctg gatgaaaacc aaataccgtt gttttattca aagatgaaaa
    22741 ttctagaaaa gtggttaaca gaataatttc acaaagtaaa tagattaaag aatataacag
    22801 cttggattta aatttcaagc tgtttctttt ttttcggaaa aagaatacga tataaagaaa
    22861 ctaagaaaaa accattattt gtacgtccgt tcacgatgtg taaataaaat aaatgtttgc
    22921 aacaaaactg tataacacca acgtttttaa atagaaacag atggttgtaa gtttgattag
    22981 aaaatagaaa aaatgcagat gaaatataaa acgctttcct tattgtgatt ttattcacta
    23041 atgctgttaa tatgcggatt ggcataattt cctttcatcg tgaaaatttg tgcttttagc
    23101 ttgtatttct cataaatcca tgataattta ttaatgaaga cggttaaata gtgatacagt
    23161 tttattcact gtttcaatcg cagaatgaag agattttctt atagatgaga gaggaatgtg
    23221 tgacaaatgg caaacaaaaa agcaccgatc gacttccaag cactgctaga tgaagtcaat
    23281 gcagatttcc cagtatatca agcacttgat caagatggaa acgtagttaa caaagattta
    23341 gtacctgatt tatccgatga tgaactcgtt gaattaatga ctcatatggt atggtctcgt
    23401 gtattagacc aacgttcaac agcgctgaac cgccaaggac gcctaggctt ttttgcacca
    23461 actgctggac aagaggcaag tcagctggct agtgcttacg catttgataa agaagatgtt
    23521 cttcttccag gttatcggga tgtacctcaa ctagtaaaac atggtttacc tttatctcaa
    23581 gcttttttat ggtctcgagg acatgctgca ggtaattctt atccggaaga attgaaagct
    23641 ctaccaccac aaattatcat cggtgcacaa tatgtacaag cagccggtgt tgcattaggt
    23701 ttgaagaaac gaaacaagaa aaatgtcgtc ttcacttata ctggtgatgg cggttcatca
    23761 caaggtgatt tttacgaagc aatcaatttc gctggcgctt accatgcaaa tgccgtattt
    23821 tatatccaaa acaacgggta tgcgatctct acacctcgtg aaaaacaaac tgcagcaaaa
    23881 acacttgcac aaaaagctgt cgcagctggg attcctggta ttcaagtcga tggaatggat
    23941 ccgcttgcag tatatactgt atctaaaatg gcacgggaat gggcgatcag tggaaatgga
    24001 ccagtcctaa tcgaaacact gacttatcgt tatggaccac atacactatc tggtgacgat
    24061 ccaacccgct accgtacaaa agacacagat gacgattggc agaaaaaaga tccattgatc
    24121 cgcttccgta aatatttgac ggaaaaagga ctttggtctg aagaaaaaga agaacaagtc
    24181 atcgaagcaa ctaaagaaga aatcaaagca gctattgctg aagccgacaa agtaccaaaa
    24241 caaaaggttt cagatttctt gaaaaacatg ttcgaagtat ctccacaatc aatcaaagaa
    24301 caaattgcaa tttatgaagc gaaggagtcg aaataatcat ggcacaaaaa acaatgatcc
    24361 aagcaatcac agatgcctta gcacttgaac tagaaaatga cgagaatgtc gttgtttttg
    24421 gtgaagatgt tgggaaaaac ggaggagttt tccgggcaac tgaaggattg caggaaaagt
    24481 tcggagaaga ccgagtattc gatactcctt tagctgaatc tggaatcgca ggattgagtt
    24541 tcggtcttgc gttagaagga tttcgtccag ttcctgaaat ccaattcttt ggttttattt
    24601 tcgaagcaat ggacgaagta gtagctcaaa tggctcgtac aagatatcga atgagcggca
    24661 ctagaaatct acccatcaca attcgttcgc catttggtgg cggtgttcat acaccagaat
    24721 tgcattcgga taatttagaa ggtttgatcg ctcagtctcc tggtattcga gtagtgattc
    24781 cttccaaccc ttatgatgca aaaggactat tgatttcttc tattagaagt aacgatccgg
    24841 ttgttttcct agaacacatg aaactatatc gctcattccg agaagaagtg ccggatgaag
    24901 cttacgaagt tcctttggat aaagcagcag ttactcgtga gggaacagat gtatctatta
    24961 tcacatacgg agcaatggtg cgtgaagcaa tcaaagcagc agacaatctt gcaaaagaaa
    25021 atatatctgt tgaaatcatt gatcttcgta cagttgcgcc attagatgta gaaacgatca
    25081 ttcaatccgt ggaaaaaact ggtcgcgtag ttgttgtcca agaagcacaa cgacaagcgg
    25141 gcgttgccgc gcaagtagtt tctgagatct cagaacgcgc tatcctttca ttagaagccc
    25201 caatcggacg agtttctgca cctgatacag tcttcccatt tggacaagca gaaaatgtct
    25261 ggttgccaaa tgcaaaagat atcgaagaca aagtaaaaga aatcgcggaa ttttaagaaa
    25321 agaagggacg aaacaaagtc atggcttatc aatttaaatt gccggatatc ggtgaaggaa
    25381 tcgcagaagg tgaaatcgtc aaatggttcg tcaaaccagg agatacgatc aatgaagatg
    25441 atacattact agaagttcaa aatgacaaat cagtagaaga aatcccgtca cctgttacag
    25501 gaacggttaa aaatgtgatt gttccagaag gtaccgtagc aaatgttggg gatgtattag
    25561 tagaaatcga tgcaccagga cacgaagaca atgaagggga cagtggtgta gccgcagaat
    25621 cccaaactcc agctaaaccg gctgctgaac ccactgttga tacagaatca gctggatcgt
    25681 caagcgaagg agtcttccaa tttaagttac cggatatcgg tgaaggaatc gcagaaggtg
    25741 aaatcgtcaa atggttcgtc aaaccaggag atacgatcaa tgaagatgat acattactag
    25801 aagttcaaaa tgacaaatca gtagaagaaa ttccgtcacc tgtcacaggg acagttaaaa
    25861 acgtgattgt tccagaaggc actgtagcaa atgttgggga tgtattagta gaaatcgatg
    25921 ctcctggaca caatagtgca ccgtcaacta gtgcgccatc agctgaagca ccaaaagaaa
    25981 aagtggaaac atcaggttca gcaagtgtcg ttgaagctgc cgatccaaat aaacgtgtat
    26041 tggctatgcc atctgttcgt caatttgccc gtgaaaaaga tgtagatatc tcacaagtaa
    26101 ctgcaactgg aaaaggtggc agagtaacaa aagaggacat cgaaaacttc ttggcaggtg
    26161 gtccaagcag tgcaccagcg aaatcagaag cgccagaagc ggcagcaccg aaagaagcag
    26221 ctcctgcagc agaaagcaaa ccagctgcac cagcaaaacc attcaagtcc aacttaggag
    26281 acttggaaga acgtgtagca atgacgccaa cacgtaaagc tatcgctaaa gcaatggtca
    26341 acagtaagca tacagctcca cacgtgacat tgcatgatga agtagaagtg tctaaactat
    26401 gggataatcg gaaacgattt aaagaagttg ctgctgcaaa tggtacgaaa cttactttct
    26461 tgccatatgt cgtgaaagct ttaacagcga ctgttaagaa atacccagta ttgaatgcat
    26521 ctatcgacga tgcaaaccaa gaaatcgttt ataaacatta ctacaatatc ggtattgcaa
    26581 ctgatacgga tcacggacta tatgtaccaa atgtgaaaga tgcagaccgc aaaggaatgt
    26641 ttgctattgc agacgaaatc aatgagaaag caaaattagc tcatgacggc aaactatctg
    26701 cagaagatat gcgcaatgga acaattacga tcagcaatat cggatctgta ggtggcggtt
    26761 ggtttacacc agtcatcaac tatccagaag tagctatttt aggtgtagga acgattgcac
    26821 aacaaccaat cgtaaatgct gaaggcgaaa tcgttgtcgg tcgtgtgatg aaactgtcat
    26881 taagtttcga tcaccgtatc gtagatggag caactgcgca acaagcaatg aataatatca
    26941 aacgtctttt agctgatcca gagctattaa tgatggaagg atgataaaca aatggtagtt
    27001 ggagattttg ctgtagaatt agatacagtt gtaattggtg cgggacctgg tggctatgta
    27061 gctgccatcc gcgctgctga aatgggacaa aaagtagcaa tcattgaaag agagtatatt
    27121 ggcggtgttt gtttgaatgt cggctgtatt ccttcaaaag cactgatagc tgcaggacac
    27181 cattatcaag agtcactaga ttctgaaatg tttggagtaa ctagtgaaaa cgtcaaacta
    27241 gattttgcaa aaacacaaga atggaaagaa aacaaagttg tccatacgtt gacttctggt
    27301 gttggtttcc tattaaaaaa acataaggtt gaaacaatcg aaggagaagc gttcttcgta
    27361 gatgatcaca cactacgcgt cattcatcca gattcagctc aaacttattc gttcaataac
    27421 gcaatcatcg caacaggttc ccgtccaatc gagattccag gatttaaatt cggaggacgt
    27481 gtgttagatt ctactggcgg attagcattg aaagaagtac ctaagaaatt tgtgatcatc
    27541 ggtggcggtg tgattggtgc cgaattgggc ggagcgtacg caaacttagg agcagaagta
    27601 acgattcttg aaggctcacc acaaatttta ccaacttacg aaaaagatct agtaaaatta
    27661 gtagaagatg atttcaagaa aaaaggcgta acagtcgtaa cgaatgcaat ggcgaaagaa
    27721 gcagtcgata acggtgacag cgtgacagtg aaatatgcag tggacgggaa agaagaatcc
    27781 gttactgctg attatgtgat ggtcactgta ggtcgtcgtc cgaatacaga tgatatgggc
    27841 ttagaacaag cgggtgtcga agtaggagaa cgaggattga tcacggtgga taaacaagga
    27901 cgtacgaacg tacctaacat ctatgccatc ggtgatatcg ttccaggggc ggcattagca
    27961 cacaaagcca gttatgaagc aaaaatcgct gctgaagcaa tctctggcaa aaaagtagct
    28021 gtagattata aagcaatgcc ggcagtagcc ttcactgatc ctgaattggc ttctgtaggt
    28081 atgacgatca aagaagcaaa agatgctggt atcgaagcaa aagcatataa attcccattt
    28141 tcagggaacg gtcgggcatt atcgcttggt aaaacagaag gattcatccg tctagttacg
    28201 acgatcgaag ataacgtgct tattggcgcg caaatcggtg gagtcggcgc aagtgatatg
    28261 gtctctgaat tagctttagc aatcgaatca ggaatgaatg ctgaagatat cgccttgacg
    28321 attcatcctc atccatctct tggcgaaatc gtcatggatg cttcggaatt agcattaggt
    28381 ttaccaatcc atatttgatt tgaataatac aggcgaaacg caactgaaaa atcagttgcg
    28441 ttttgttttt tagaattatc aataatatta ttatgtaaac ttaaaaatat gacaacttct
    28501 tggtttatta ccacttccta tgctacactg aagaggaata tgaaatagga gagttgaaga
    28561 tgcaagaata tcagtatcca cttgatttag attggacaac agacgaaatg gtcattgtaa
    28621 tgaagatgtg ggaagatctg gaacgtgcga atgaaaaagg gataaacaat gaagcttttt
    28681 tgaagactta tcagcagttt aaaactgttg tcaaatccat tggtgaggaa aaacgattgg
    28741 gacgggaatt tgaaaaagct tccggttatt ctttatatcg tacagtgcag caagcaaaaa
    28801 aaatccaaac aaaactttga gaatgaacgg gtgagataaa tggaacagat gattgatcat
    28861 atcaagtcct ggcttgaaga agctggtgag aaaatcaaat cttctcaaca aacattaaca
    28921 atctcgcaaa aatcaaatcg aacggatcta gtaacaaatg tcgatcgaaa catccagaat
    28981 tttctaatcg aaaaaatcca ttcctttgat ccagaggcga aaatattggc agaagaagaa
    29041 gggtgtaatc aattatcgga tctcgatgga agagtcttta tcatcgatcc tattgatggc
    29101 accttgaatt ttgtgattga aggggaaaat ttttgtatta tgctcgctgt ttatgaatcc
    29161 ggcgttggaa agcttggttt catttatgac gtgatgagaa atgaactttt ttggggtgga
    29221 aaaggaatag gcgtgtataa aaatgatgag ccattgccta gaccagcaaa taaatcctta
    29281 tcggaaggct tacttggtgt gaatagttat cttttcggtc ataataaata tggaatccga
    29341 gaaattgcgg aaagcagcat ggggacacgt atgtacggat gcgctggtct tgaactagtg
    29401 gcaatcttga aaggaaacca cattgcttat atttcaaacc ttagcccttg ggattatgca
    29461 gcgggaaatg tcttattgga agagtttggt atggtaacaa gcggtctttt tggtactcct
    29521 ttgacatttg aaaaaaggga atactattta gcagggactt cttgtgcata tgcagaaatc
    29581 gcagaccttt tgaaaaaaga aggctgaaaa aaaggtagaa atcattcaca aaaatgataa
    29641 aaacgagcaa aagattaatt ttctcgaaaa aatgaaaaca ttttactata tttcatgaaa
    29701 aaagtctgct ataattagca gtcgagtaaa atttgccctg tcataaagaa ccaataaaaa
    29761 aggagttagt tacattgaat tatagaaacg atatccgtaa cgtcgcaatt attgcccacg
    29821 ttgaccacgg aaaaacaaca ttagttgatg aactattaaa acaatcagat acattagacg
    29881 cacatacgca attgcaagaa cgtgcgatgg actcaaatgc gctagaaaaa gaacgtggta
    29941 tcacgatttt agccaaaaac acagctgtag actataaagg tattcgcgta aacatcatgg
    30001 atactccagg acacgcggac ttcggtggcg aagtagaacg gatcatgaaa atggttgacg
    30061 gcgttgtgtt ggtcgtagat gcgtatgaag gaacaatgcc tcaaacacgt tttgtattga
    30121 aaaaagcact ggaacaacat atcacaccaa tcgttgtcgt aaacaagatt gacaaacctt
    30181 ctgctcgtcc tgagcatgtc gtagatgaag ttcttgaact attcatcgaa ttaggagcag
    30241 atgatgatca gttagacttt cctgtgattt atgcatctgc actaaatggt acgtcaagct
    30301 tgtcagatga tccagcagat caagaaccaa ccatggcacc tatttttgat acaattattg
    30361 aaaaaatccc tgctcctgtc gataacagcg acgaaccatt acaattccaa gtttcattac
    30421 ttgactacaa cgattatgta ggtcgtatcg gaatcggacg tgtatttaga ggaacaatca
    30481 aagtaggaga ccaagtagca ttaattaaat tagacggaac agttaagaaa ttccgtgtaa
    30541 cgaaattatt tggtttcttt ggactaaaac gtctagagat tcaagaagca aaagctggag
    30601 acttgattgc tgtctcaggt atggaagata tctttgtcgg tgaaacagtt actcctgtgg
    30661 atcatcaaga tgcgttacct atccttcaca ttgacgaacc aacattgcaa atgactttct
    30721 tagttaataa ttcaccattt gccggtcgag aaggtaaatt cgtaaccgct cgtaagattg
    30781 aagaacgttt gatggcagaa cttcaaacag atgtatcctt acgagttgaa ccaacaaact
    30841 ctccagatgc atggacagtt tctggtcgtg gagaattgca tttgtctatc ttgattgaaa
    30901 acatgcgccg tgagggatac gaattgcaag tatctcgtcc agaagttatt gaaaaagaaa
    30961 tcgacggtgt aaaatgcgaa ccgtttgaac gcgtgcaaat cgatacacca gaagaatata
    31021 tgggtagtgt tatcgagtcc ttgagcttac gtaaaggtga aatgcaagat atggtccata
    31081 caggaaacgg acaaatccgt ttgacattct taacacctgc ccgcggtttg attggttatt
    31141 caactgaatt cctttcaatg acacgtggtt acggaatcat gaaccatact tttgaccaat
    31201 atctgccaat gcttcctggt caaattggcg gacgtcacca aggggcgctt gtttcgatcg
    31261 atacaggaaa agcaacgact tattctatca tgagtatcga agaacgcggt acagtcttcg
    31321 tagaaccagg tacagaagta tatgaaggaa tgattatcgg ggaaaacagc cgtgataatg
    31381 atttgactgt caacatcacg aaagcaaaac aaatgacaaa cgtacggtct gctactaaag
    31441 accaaacatc tgtcatcaaa aaaccaaaac aattgacgtt ggaagaatct ttggaattct
    31501 tgaatgatga tgaatattgc gaagtaacac cagaaagcat tcgcttgaga aaacaaattt
    31561 tagagaaaaa tgctcgtgaa aaagcatcta aaaagaaaaa ataatctgta aaaggatgaa
    31621 gagagaaacc agcttgttat aaaaaatagc tggtttcttt ttttgtccaa ctcttttctg
    31681 tggagaagtc atctttgtca atggacataa attcagaaaa tacgccgaaa gacgtttaaa
    31741 agacttttaa aaaacttatt tctagagagt ttttgtttca taataagata atgtttcacg
    31801 aaaggagatc aacttgtcct tcgaagaaaa tcgaagtaaa atggcaagag aaaggagcgg
    31861 gaagatgaac gacttattaa aacaatactt tggctatgat gagtttagac ctggtcaaaa
    31921 agaaattatc cagaaagtca ttgatcagga aaatgtatta ggaatcatgc ctaccggaag
    31981 tgggaaatca atctgttacc agcttccagc tttactatta gatgggctta ctgtggttgt
    32041 gtccccttta atctctttga tgaaggatca ggtggacgcg gcgaatcaat taggtatacc
    32101 cgccactttt atcaatagct cgttagatgg ttacgaaaca gctagacgct tccaagaaat
    32161 cgatagacag cagtaccgtt tactttatat cgctcctgaa cgttttatca tgccggattt
    32221 tatccaagca atgaagcgat ggaacgtccg tatgatcgct attgacgagg cacattgtat
    32281 ctctcagtgg gggcatgatt tccgcccaag ttatttacag atggcgaacc agctagatca
    32341 actgccaaat cgtcctgtaa ttgttgcttt gacagctaca gcgactgtgc aagtagctgc
    32401 tgacataaaa agacttttaa aaattccaga aaacaaccat attcagactg gttttgaacg
    32461 agaaaatcta cgatttcaag taattaaaga tcaaaaaaaa gaacaatatc taatcgaata
    32521 tttaaagatc aacaaaaatc aatctggtat catttatgca gcaacgagaa aagaagtaga
    32581 ccgtctctat catttgctta aaaaattcga tttttccgtg ggtagatatc atggtggtct
    32641 aaatgagaat gagcgaacag aaatgcaaga agccttttta tacgatcgct tgcagctgat
    32701 tgtagcgaca aatgcatttg gtatgggtat aaataaaagc aatgtccgtt ttgttatcca
    32761 ttatcaaatt cctggctctc tagaagcata ctatcaggaa gctggtcggg cgggaagaga
    32821 tggtctttcc agtgaagcca tcctgctttt ctctcctcaa gatatccaag tccaaaagtt
    32881 ttttatccag cagtcccaaa gagaagaagg gcaaaagcaa aaagaatatg aaaaattaaa
    32941 agcgatgaca gaatacgtgt atattgagtc ctgtcttcag caatacatcc taaactattt
    33001 tggcgagaca agcagtccgt gcaaccgttg tggtaactgt ttagatgaca gagaaatagt
    33061 agaagtaacg acagaagcac agatggttct ttcttgctta aaacgtatgg gtgagaacta
    33121 tggtaaacaa atgctgatga aagtcttagc aggatcgaaa gaacaaaagc tgcaagcttt
    33181 aggttttgga catttatcta cctatggact gatgaaaaac caatcgcaaa aagaaacgat
    33241 gcagttaatt gaatatttga tatcgaatgg ctatcttctg accatcaatg gtgagtatcc
    33301 tgttttgaaa gtaacagaaa gagggataca agtattgaaa ggacaagaat ctgtttatcg
    33361 aaaggaaccc aagaaagtcc agcagctatc ggatgaagaa accgatacac tatttgaagt
    33421 gctgcgggaa ctgcgaacgg atctagcatc agaagcaggc gttcccccgt atgtcgtatt
    33481 ttcagattcc acattgaaag aaatgagccg aatacgtcca tcaagcagat tggagatgct
    33541 tcagataaaa ggagttggcc aaagcaagct tgataaatat ggcgaagcct ttttatctcg
    33601 gataaaaaat gcggactcta acgttctgga taagtagaaa gaacgaatac gtaaaaatga
    33661 ataaaaacaa ctggttaaat ctgttttttt tgctccttat gaaaatcaaa tatgttataa
    33721 ttaaggaatt agaatgggag gtaagcacag atggattctt tgtcgaaaaa acttgcgatc
    33781 caagtattaa atgatgaagc agaacggatc aaacgattaa tccgaaatca aaacaacagt
    33841 ctctgtatct cacaatgcaa agccttcgaa gaagtggtag atacacagat gtacggcttt
    33901 tcccggcaag tcggttttgc tgtccgtata ggagtaatcg gaaagaacga gggccagctg
    33961 atgttaagtg agctagaacg agaattgaat cagttatata gtgaggttta ccaagaaatt
    34021 tatgataaaa aagaagttgg caaggaggaa tagacttgcc taagaaagtg aaaaaaaggc
    34081 atctattaga ctatagcatc ttgattccct atttaatttt atgtgtattg ggattgatca
    34141 tggtatatag ttctacgtcg tatctattat tagaaaacgg acaaaatccg tccgcatcag
    34201 tcattaacca gagtattttt tgggtgctta gcttgattgc tatcgcacta ctttataaaa
    34261 tgaaaacaga tgttttgaaa aaccagcgtt tgatcatggc agccatcgca gttttgacga
    34321 ttttgctgct gattgttgtg ttttttggta aggagatcaa tggggcgaaa ggttggctgc
    34381 aaattgcagg attctcgatc caacctgccg aatacctaaa aatcatttct atctggtacc
    34441 tgtctctgac tttatctaaa agacaaaaca gtgtacaaaa agattttctt gggactgtga
    34501 aacgtccact tgcaatggtt atcggactta ctgcattagt cgctattctt cccgattttg
    34561 gtaatgcggc agttatcttt ttgattattt tggttctgct tttagccagc ggagtcaatt
    34621 atgtgtatac tttgattgta ggagtaggag gcttttgtct aagtactttt acgatctggc
    34681 tgatcaatat cacaaacgga aagatcttac ccggacgttt acagtatatc tataatcgat
    34741 ttgctattta ccaaaatcct ttctcagacg aattaaataa agggcatcaa ctagtcaacg
    34801 gctactatgc catgttcaac ggaggactat ttggcagggg attaggtaac agtatccaga
    34861 aaaaaggatt tttacaagaa gcacaaaccg attttattta tgcaatcgta gtggaagaac
    34921 tgggagtgat tatggggatt ttgatattag cgttgctatt ctttatgatt gtgcgcattg
    34981 tccttgtagg tatccgttca aaagatccgt tcaattcgct tttgtgcatt gggatcggcg
    35041 caatgttttt gatccaagta tttgtcaatc ttggaggaat tactggcgtt attcctttga
    35101 cagggatcac gttcccattt ttaagtcaag gaggctccag tttgctgatg ctttcgattt
    35161 gtgtcggctt tgtcctcaac atcagtgcgg atgaaaaacg caagagctta ggtttataat
    35221 aaaaaaagat gtaggagtgg ttcgatgaaa aaagttttag ttgctaacag gggtgaaatc
    35281 gctgtacgtg tatttcgtgc ttgtacagaa ttaggaatta aaactgttgg aatctatgca
    35341 gaagaagatg aatattccgt acaccgtttc aaagcggatg aagcatattt agtaggacaa
    35401 ggaaaaaaac cgattgatgc gtatctagat attgaaggga tcatttctat cgcgaaagaa
    35461 tgcggagctg acgctattca tccgggttac ggtcttttgt cggaaaactt gaattttgcg
    35521 caacggtgcg aagaagaagg catcattttt gttggaccca aactgcatca tttagatatt
    35581 tttggagata aaatcaaagc aaaagctgca gctatcgaag cggggattgc ttcgattcca
    35641 ggcacagatg gaccaatcgc ttctatagac gatgccttgg agtttgcgaa acaatacggt
    35701 tatccgatta tgatcaaggc agctctaggc ggcggcggac gcggcatgcg tgtagctcac
    35761 gatgaaaaga gtgcaagaga gggctacgaa cgtgcgaaaa gcgaagcaaa agcagccttt
    35821 ggtagtgatg aagtgtatgt tgaaaaatac atcgctaatc ctaagcatat cgaagtacag
    35881 attctcgggg atacgcatgg aaacgtcatc catctttttg aaagagattg ttctgttcag
    35941 cgccgtcacc aaaaagtagt agaagtagcg ccttgtgtct ctatgaatga acagcaacgt
    36001 caaaaaatct gccaggcagc tgtccaattg atgaaatatg tcgggtatgt caacgcaggt
    36061 acagtagaat ttcttgttga aggagatgat ttttacttta tcgaagtcaa ccctcgcgtc
    36121 caagtggaac atacgatcac agaaatgatt acagatattg atatcgtaac aacgcaactg
    36181 ttgattgctc aaggtttgga tctgcataaa gaaatcggat tgcctcagca agaaggaatt
    36241 aaattaaatg gttcagccat tcaatgccga atcactacag aagacccgtt gaataacttt
    36301 ttaccagaca cagggaaaat cgatacgtat cgttcacctg gtggttttgg cgtacgtctg
    36361 gatgtcggaa atgcttacgc gggctatgta gtgacaccgt attttgattc attgctagta
    36421 aaagtatgta cgcatggtgc tacctttgaa acagccattc agaaaatgga acgttgcttg
    36481 aaagaattta gaatccgtgg agtgaaaaca aacattccat ttatgctcaa tgtcatcaca
    36541 catcctgaat tccaatcagg aaatgcaaaa acaaccttca ttgatagtac agcaacatta
    36601 tttgaatttc ctcgactacg agaccgcgga aacaaaacga tgaaatatat cggtgaaatt
    36661 actgtgaatg gttttccagg tatcgaaagt ggcgaaaaac cattttatga agaaccacgt
    36721 atgcctaaag atctaatcac aagaactgat tacgtaacgg ctaagaatgt attagatgcg
    36781 aagggtgccg atgctttggt cgaatggatc aaaggacagg aaaatttgtt gttgacggat
    36841 acgacattta gagacgccca tcaaagtctg ctagcaactc gtgttcggac aaaggatttc
    36901 aagcagattg cacgtttgac tggagaaggt cttcctgaac tcttttcaag tgagatgtgg
    36961 gggggagcaa catttgatgt ggcttaccgc tttttgaatg aagatccttg gcaacggttg
    37021 agaaaaattc gttctttaat gcctaatacg ttgctgcaaa tgcttttcag aggttcaaat
    37081 gccgttgggt attctaatta tcctgacaat gtattggtgg aatttgtcaa agaagcagca
    37141 gcgcaaggaa tcgatgtatt tcgaatcttt gatagtttga actggactcc acaaatggaa
    37201 aaaagtatcc aagctgtacg ggatactggt aaaatcgcag aggcagctat ttgctatact
    37261 ggcgatatca acgatccaag tcgggcaaaa tacaatgttc agtattataa agacatggca
    37321 aaggaactag aacaactggg tgcgcatatc attgcaatca aagatatggc tgggctgctt
    37381 aaaccgcagg cagcttatcg tttgattagt gaattgaaag aaacgacaga tctgccaatc
    37441 catctgcata ctcatgatac cagcgggaat ggaatcatca cttattctgc tgcttcaaaa
    37501 gcaggagtag acatcgttga cgtggcaatg agtgcaatga gtgggaatac tagtcagcct
    37561 agcatgagca gcttgtatta tgcactggtc aatggtccac ggctgccaga aatcacgatt
    37621 gaaaatgcac agaaattaaa ccattattgg gaagatgtgc gcatgtatta caaaccgttt
    37681 gaaaacggct tgaatgctcc tgaaacagaa gtatatatgc atgaaatgcc aggaggacag
    37741 tattcgaatc tacagcaaca ggcaaaagct gtcggattag gtcatcgctg ggatgaaatc
    37801 aaacaaatgt atcatactgt caacttgatg tttggcgata tcgttaaagt aactccatca
    37861 tctaaagtag ttggagatat ggcactattt atggtccaaa atgatcttac agaagaagat
    37921 atttatgaaa aaggcgaaac actaagtttc cctgaatctg ttgtgacttt cttccaagga
    37981 gaactagggc aacccgttgg cggatttcct aaaaaattgc aaaagattat tcttaaaggc
    38041 agacctgcat tgaatgaacg tccaggtctt ttggctgaat cagtcgactt caacgaagta
    38101 aaaaaagaat tggcagaaaa aattggctat gaaccaaaac aagacgaagt attaagctat
    38161 ttgatgtatc cgcaagtctt tttggactat caaaaagcat ataatcaatt tggcgatgtt
    38221 acattactgg acacaccaac atttttccaa ggtatacgtt tgggtgaaac aatcaatgta
    38281 caaatcgaac gcggaaaaac gcttatcatt cgtttagatg aaatcggaga acccgatatc
    38341 gaagggaatc gcgtactgtt cttcaatttg aatggacaaa gacgtgaaat cactatcaaa
    38401 gataattcga tcatcagtac ggtccaaacc cgattgaaag ctgaaccgac aaaccgagaa
    38461 caaattggag caacgatgtc tggttctgtt ttggatgtat tagtgaaaaa aggcgataac
    38521 gttaaaaaag gtgatacgtt gatgattact gaagcgatga aaatggaaac ggccatcgaa
    38581 gcacgttttg acggagaagt cgcacatgta tatgtgtctt caggagacac tatttcgtct
    38641 ggtgaccttt tgattgaagt gactgagaaa taataagcga aaggtgggga aacatgaaaa
    38701 gactgggttt gttttggctg attctgctat tagttattgt ggcattctac atggaaccag
    38761 tcttgtttcc gccaaaactt gaagtgaagg aaaactctga tcaacaaata tcaaaccaaa
    38821 tgacaacgtg gaaataccag gagcttaaag caactggttt ttctacttat atcggaaaac
    38881 cgatcgatca gctggaaaag gattttggcc aagcctatga tcgattaact agcggatttg
    38941 gttttgaaac aagatattat gaaaataaag ctagtcatct cacatttgaa gcgaacatcc
    39001 aagacagcag agtcacaact gttaaagtac tgcaaacagg gcctgctgat atcgcgccgt
    39061 tttatttagg gatgacgatg caagatctta cgaaaatcac tactatctat actaatttca
    39121 cttttgagta ccatgataca gaagttggaa tcgaactaat ggaagaggat atgaattatc
    39181 gtccgctaat tgcttttgat aacgacactt ttgctatttt attttttgat caaacaacaa
    39241 acggcctatt ttcagttgtg tatttagata aagatagtct tttgaaacta ttgccatatc
    39301 aagtgtttgg tgaaggcctt ccacattatc aagcagataa atcggctgat tgggaatcaa
    39361 tcaatcgcgt taaagaacga aaaagtacga ctttattaaa tatgcttaga agagaagacg
    39421 aacttcccat atacaatcaa acacttgcct ttcaaaacca cagtcagctg ctactacatg
    39481 attttttgac aaggcctgag gaaatattgt cagaggaacg tatggctgat tggcaaaaat
    39541 cgctaggcag tgctcaaacg acagtgaaat tctcactgac gaatgatgaa ttggagaagt
    39601 taatcagtaa acaaaaatta gaaaatacta gtgggctatt tattcatccg gcgattgacg
    39661 ctactttttc gtttttatat tggtacagcg atccttacaa ccatgaccgt ttcatggacc
    39721 cgggaacgga ttctgtaggc attgcttttt ctaaagaaaa tatgttagtc ttattgcaag
    39781 aagaaaacgg agaaagtagt gatagcagtg atcgttaacg aagagctgtt tcaactggag
    39841 gatcaatgcc tccaagtcgc tgaaatgata aaaaagagta aaacgatggc ttcttatctt
    39901 gaacataaac agtcaatgga agaatctgca aaagtttgcc agttgaaaga agcgttcttg
    39961 tctaagaaag aagcatttga aaatgtagcg gcatatggtg agtatgcacc tgattatcgt
    40021 gaaaaaaaac gagctgttcg aaaagcaaaa agacagcttg atatggatga gcatgttgca
    40081 gctttccgat atagtgaaac acagctgcaa agtctgttgg atcaaattgt ccaagtactt
    40141 gccgaagaag tttctaatga aatcaaagta gatgcaggta gcccgttttt tgaaacgaaa
    40201 aaacactttg gatgcggagg taattgtcat gcaattagac aatagtgaat ttgaaataac
    40261 aaaacgacgc gggctgatcg tatgggtcta cagcttaaaa caattaaaga atctgaaaaa
    40321 gttcggcttg ttgcattatg tctcaagaag aatgaaatat gtcgtgcttt acttaaatga
    40381 agagacattg gaagaaacag aagaacgaat ccgtaaatta cattttgttc gaaacgtaga
    40441 acgttcttac cgaccggata tcgaaatgaa ttttgccgaa aaaataggaa acaaaacagt
    40501 attaaaagac gaaggtttcg aaattgaaga gctaaataca gaaatccgat tagctgaaca
    40561 tctttaaaaa tctcttatga gcagttttta aataaaaaat aacttggata acgatcgatt
    40621 tttgatcatt gtccaagtat ttttttggta tactagtacc agtaccattt ctaaggagtg
    40681 agtagatgcg gataatatca ggaaattatg gcgggcgccg tttaaaaagt ttagcagggg
    40741 cgaacaccag accaactaca gataaagtaa aagaatccat attcaatatg attggaccat
    40801 attttgatgg agagacagta ttggatctgt ttgcaggaag cggtggttta gctatcgaag
    40861 cagtatctag aggctgcagt catgcggtat gcgtagacaa aaattaccaa gcgctaaaaa
    40921 tcatcaaaga aaacatcgaa attacgaaag aaccagagaa atttaccaca ataaaacttg
    40981 atgcggacaa agcaatcgaa cggctagcag cggagaaaca acaattcgac tacttgtttc
    41041 ttgatccgcc atatgcaaaa caaaaaataa tcgatcaaat ccataaaatg gaagaactgg
    41101 gacttttttc taaaaccgca gttatcgtat gcgaaacgga taaaacagtc gaattgccag
    41161 aaactgtggc tggattccat caaataagaa aacagattta tggcataacg gccgtaacta
    41221 tctatagaaa agagggaaat caatgaaacg tgcattattc ccaggaagtt ttgatccttt
    41281 tacaaaaggt cacttagata cggtggaacg tgcggctaaa ttattcgatg aggtagtaat
    41341 tggtgttttt atcaatactt caaagaaaag tttgtttccc ccagaagaaa gaatgacatt
    41401 gatcacaaaa gctgtttctc atcttcctaa tgtaaaagtc atgcatcaag aaaatcaatt
    41461 gacggtagaa acagcaaaag agattggtgc agatgcgttg atcagaggca tacgaagtat
    41521 caaagacttt gaatatgaac gagagattgc tcagatgaat catcatctat atgatgaatt
    41581 ggaaactgtc ttcttattag caaaaccaga atatagtcac gtgagttcca gtattttaaa
    41641 agaagtactg cactttggcg gagatgtgag cagctactta ccgccagtga tcaacgaagc
    41701 tttagctgga aagcgtgaat caaatgaaag ctaaacaatg gttgaaaaca gtactgatta
    41761 tcatatttgg aatgttgatc attggatttg tagtagttcc cttgccgtat tatgtagaat
    41821 caccgggagc cacgatcgat ctgaaagaac taattacggt caatgataag gaagataaag
    41881 gttctgggtc tttctctctt acctctgttg gtatcaggca agctacaggt ttcttagctt
    41941 taaaagctaa aatgacccct tttgaagaat tgatcagtga agaagaattg actggtgggg
    42001 cgacaaatga agaatataat caaatgcaac agtattatat ggattcttcc caaaatgcag
    42061 caatcgaaca agcgttaaaa cttgcagaca agccttataa aatggaattc aaaggcgtat
    42121 atgtcatgag tgtagagaaa acatcgaatt tctttggcaa gctttcagtt ggagatacag
    42181 taacaaaagt agacgggaaa agctttcaaa gtacagaagc atttatggat tatgtaaaaa
    42241 gccaaaaagt tggacaaaca atcgaaatca gttatttgca taatggtgaa gaaaaaacag
    42301 cttctggtga tctgatcgag ttaccaacag ataaaaaggc aggaataggt atcacgctta
    42361 ctgaccatac cgagatcgaa tcagatacag atgttcgtat taattctggc tctatcggtg
    42421 ggccatcagc gggattgatg ttcactttag aaatctatga acaagtcact ggtaaaaact
    42481 tgcgacatgg taagcaaatt gcaggaactg gaacgatcaa cagtgaagga gaagttggcc
    42541 gaatcggagg aatcgataaa aaagtggcaa gtgcggataa agctggcgta gagattttct
    42601 ttgcaccaga tgatacgatt tcagacgatg ttaagaaaga atatcctgaa ataaaaacca
    42661 actacgaaga agcaaaagct gccgctaaaa aattgaattc ctcaatgaaa atcgtaccag
    42721 taaaaacagt acaagaagcg cttgactatc tagagaaaat gaaatgaaac taaataatta
    42781 aagaggggtt gtgacacgag ttctgtcaca acccctcttt ttcgtcaaaa atcttcacga
    42841 taaaaataaa aacaaaagaa aaaattgacg taattagatg ttgaagggac gattttgcca
    42901 gagctcactg tttcttcaat tttaaatgaa aggagtaatg aatgattttt actggtcatt
    42961 ctttgaaaaa agaacaatga tagaaaaaat cagcaagaaa atactagctt cacccaaatt
    43021 gatcatttgg atgtctatga tagttcttat cttttgtatc gcaagtggtt ttttattatc
    43081 aaatttgcta ttttatagag aaacagaaga gactgctgca aaagaaatac tttcttcgtt
    43141 tagttccagt ggagaagatc catcagctga aggaaacgat gtagaagagg atgctcgtcc
    43201 aaaggtcatg tacaccgata tcaaaggaag tgtgaaggag cctggtatct attccttttc
    43261 ttcagaagaa cgggtctatg atgtactaaa gcgtgcaggt ggattattag aagaagcgga
    43321 tagcgatcga atcaactttt ctgcgaagat agaagatcag caagtcctat atatccctgc
    43381 tgtaggtgaa gagctgccag aacatcttga tcagttggca tcctcggaag gaaaacagcc
    43441 tacagcagat tccgagcctc ccaaaataaa tatcaataca gccactccat cagaacttca
    43501 gcagattcct gggatcggat cagtcaaagc gcaagaaatc attcgattta gagaagaaaa
    43561 cggatccttc cagaaagtgg aagacctgca ggagatttct ggtatcggtg aaaagacagt
    43621 tgaaaaacta aaaaacttcg ttacaattaa atagaatgat tcaaaatcga ctggcacgag
    43681 caataaatgg acgctaatgg atactaagaa taatccaatt ctaagagctt ggcaggacga
    43741 ggaggtagta tttttggata ggaaatagct tgattgttcg caaagaaaca ttaaaaaaac
    43801 caatgctgaa tgtctatctc caaaataaaa tatctgggat tcatattatg aatacggctg
    43861 tcagcggcaa taacagtcaa gctctacgag aacgctttgc caaagatgta cttagctata
    43921 cagcagataa agtatttatt ctcattggga cgaatgatct agcagagcat aaacaacttt
    43981 ctaaagaaac gtaccaaaaa atctgcagtg gatgatagtt cagctgaaaa aagactatag
    44041 ttctgatcat gctttcttta tcacgccacc agcagtcgat gagacaaaac aaaaatatcg
    44101 gaataacaag ttgatcaaag aatatatctc tgttctcaca gaagtagcaa aacgccatga
    44161 ttgtgaagta tcgattttta tacggaattt cttgaacaaa tggattcgaa gaatttttat
    44221 aatgggctaa tggatgacgg acttcatttc ggcagtgaag ggtaggatct tttgtcagac
    44281 aggatgattc gttatattta aagaatattt tgtttaagca atgagtactt tttaatcaac
    44341 ttgaaaaaac ggaggaatat aaaacatgtt agaaaaatct tcaaaagcat gcgatacgaa
    44401 taaagaaaaa gttactgata agtcacataa tgaacgcatt ccttgggacc agtactttat
    44461 ggctcaggca gtactgttat ctttacgtag tacgtgtaca cgtttagaag taggagcgac
    44521 actcgttcga gaaaaaagga tcattgctgg cggctataat ggagcagtca gtggagatgt
    44581 ccactgcata gatgaagggt gttacgtcgt ggatggacac tgcttgcgaa cgatccatgc
    44641 agagatgaat gcactcctac agtgtgcaaa acttggtatc ccgacggaag gttcagaaat
    44701 ctatgtcaca cattttccat gtttggcctg tacaaaggct ttgttgcaag ctggtgtgaa
    44761 agggatcaat tatctccatg actatcgaaa tgatccttat gcccaagcgt tgatcgaaca
    44821 attaggtgta tctgtacacc aagttgcttt agactcacag catttttcaa aacttcaaaa
    44881 tgaattaaca ggaaaacatg tctagcgttt tagaaaggca tgttcgaaat cggttgattt
    44941 ttccggcaat tacgtcgatg attatctgtt tgttgtatta cactgacaat tggggttatc
    45001 gtttgcttct tgccggaatt tttttatggt tttcgctaaa agaaggacgt tttatcgcgt
    45061 acttgtgtat tttgtgtagc ataacggtat ccatttctta taggctacaa gagtattcat
    45121 ttttagagga aaaaacaaca tctgcgcaaa ttactgtatt tacagatacg attcgtgcaa
    45181 atggtaattt tttgacaatg gaaggaaggt tatcagagaa taaacaaaag ctccagcttt
    45241 cttatcaagt aaacacagaa gcagaattga aaacatggct taacttccga ggaaagggaa
    45301 tagaattgac tgctgaaggc gagttcatct ctccagcaaa aaagcggaat ctttataatt
    45361 ttgaccaaga agcttacttc aggaaccata gaatttctgg acggttccaa attcaaaaga
    45421 ttgaacagat caccatgcaa aatcactggc gaaactggct tcagagaaaa agaggatctt
    45481 ttatctcctt tgtccaatct gaatttccgc aaaaaacaag tgtatatatt aattctttat
    45541 tatggggcta taaagatgca ggattcagag aaccagaaga aatttttagg gagagtggtt
    45601 tgctgcatct gttcagtcta tcgggtctac acatccaatt ttatttaggg tggctgtatt
    45661 atttatttcg acgtatcgga tggccactac acgtcagtat tattccgttg agtctactaa
    45721 ctatctgtta tgtttctatt gcaggaagtt ctatttctgt tttgcgtgct agtttgctgt
    45781 ttttattgcg attgctagtc aaattgctga ataagcatta ttccaccatg gacttatttg
    45841 cagttgtctt ttggcttctt ttactatttg atcctcgatt tctttttcat gcgggtggac
    45901 agcttagttt tttcatgagt tttttgttta tcctgatttc ttttgatgga gattggttga
    45961 aaaaaacggc ctctcacgtc ctgtttacta tgatcacgat gccgttgatt gtatggcatt
    46021 tttatgagtg gcctatttta ggtagtcttt ttacattact gattgcaccg gtattcaagt
    46081 ttctttttct tcctggtgtg ttatttctca cactcttcaa tcgctggctg ccggaaactt
    46141 tacttttgct gatagaagag ggattaatct tatttgagcg aataatcgat ttttcttcag
    46201 ggtcgtctct cattatagga cgtttgcccc ttgtgctatc tgggatgtat attttcggat
    46261 tactgatttg tatggatagg ttgaaagaac aacctgtgaa acacttgttt tatgttggtc
    46321 ttttttcttt tatttttttg actttgccat ttttacgctt ttcttcaacg atcgctttta
    46381 tcgatgtcgg tcaaggagac agtatctttt tgcaaagtcc ttttcgaaaa gaaacgattt
    46441 tgatcgatac tggaggtcag ttacactttg aaagagaaaa gtgggcgcaa ggtatgatac
    46501 gtcctcctgc tgaaagaaat atcgttccat atctaaaagg tcaggggata agtgtaatcg
    46561 ataaactcat cttgacacac gacgatacgg atcatgtggg agaattaccc acgttatctc
    46621 agcattttac tatcaaaaaa atttatatcg gttggggcgc tggacgaaat gagccattac
    46681 aaaggcattt atctgaagct caaaaaaatg gtactgagat cattgaaatc aaacatgggg
    46741 acaggatcag cggttattat gatctttatg tattgactcc ttttgaaaag ggagagggaa
    46801 gaaatgaaga ttcgattggt ctatggatgg aatataacaa taggcgcttt ttatttttag
    46861 gagatttgaa tcaagcaatg gaaaaacaat tgcttttgat ttatcctaat ctgaaagccg
    46921 atgtagtcaa attaggtcat cacggtagcc gtacgtcaag taacacagat tttctttccc
    46981 atattgaagc aaaacatggg attatatcct gcggcgtaaa taatcgttat ggtcacccgc
    47041 acagcgaagt attggagaca ctagaagaaa atcagataaa aacatggcga acggatcaac
    47101 aaggaatgat cacctatcgc tggcatccag tttttcatcc tcatgggcta gtggaaacaa
    47161 tgatagacta gtaattctca tctgctcatg gtaggataat ttttgaaagt ggtgagtaat
    47221 ttgagtatac aagcagagtt acaaaaaata cgtaaagaaa aacttgcatc ttgttacttg
    47281 attttaggaa cagaaaagtt tctccaagat caagttcgga cagaaattgt caaaaaaatc
    47341 caattagagg gcgaagatga cttaaatttt ttaagttttg acatggaaaa tgcaagttta
    47401 gatgaggtag tagctgaagc agagacgttg ccgtttttcg gagatcaacg gttagtattc
    47461 gtagagaatc cttatttttt aacaggtgaa aaagtaaaca atggaatcga acaaaatact
    47521 gatttattga cggcttattt gaaagaacca ttagaatcga ctgtattagt attctttgcg
    47581 ccatatgaaa agttggatga acggaaaaaa gtaacgaaac aattgaaaaa aacagcaatt
    47641 atcatcaatg tccaacagtt gaatgaaaaa gaagtacgtc aatatctgat gaatacctta
    47701 gagaattcct caatcaaaat ggaacgaagt gcaattgatt tattcttgag gttgaccgac
    47761 ttagatttat ccaaaatgat gagagagtta cagaaattgg tcctttatgg acaaaatcaa
    47821 cagcaaatca cggtaagaga agtagaagaa ttagttccta aaacgttaga acataatatt
    47881 tttgacatga cccaatatat tttaaaaggg aagacggaac aagctttgcg tttatacgaa
    47941 gatttagtta tgcaagggga agaaacaatc aaaattaatg cgattttgct ttctcaatta
    48001 cgtttatttt tacagacaaa atttcttgta aagattggtt atcagcaggc aaatattgct
    48061 gaaacattga aaatccatcc atatcgtgta aaacttgcca tgcaggaagt aaaaaaattc
    48121 gatgaacatt tgctggtaca gttgtttgat caattagttg agatggatta tcaaatcaaa
    48181 acgggacaaa tcgaaaaaga attaagtttt caactattcg ttttgcgcac agggcagttg
    48241 ttaagaaatc gataagaaga aagacgagga caaagcatgc gggaaggtcg tttgtttttg
    48301 tccttttttt gacaaataaa aaaatcggcc gaagccgatt cttttattta gcgatttttt
    48361 tgcttaaacg agatttgtcg cggttagctt tgtttttgtg gattagacct tttgattcag
    48421 ccatatcaat agctttaaca gcttctttat ataacgcatc tacgttgtca gcacctgaag
    48481 ctacagcatc ttcaaatttt ttgattgcag tacgcatagc gcttgtttga gatgaatttt
    48541 tcacattagc gttttcgctt gtacgaacac gtttgattgc agattcaatg tttggcatta
    48601 gtttcacctc cgataactta agttcttacg cgtgttaccg cataattcaa cattcattat
    48661 tatacctaaa ggcagcgtgc tttgcaatat gaacatgaca agtttttttc cttaacagtc
    48721 ttttattagg attttttttc agtaaaaacg gatagtacaa gctgaaaaaa atcaaaaaga
    48781 cgctattgtg ggaggcaata gcgtcaaacc aaactagatt tttatttatc tatttaaaca
    48841 aagtttgaat gggaatgttt ggtactaagt tattatataa caaagagaac cgtttgcaaa
    48901 gttttttttg aaaagggata cgattccctg ttgttctttg tttttctatt aagaaactgc
    48961 agttatttta taaccagtat cctttgatca gtaaaggcta ttctggtgta ccgattattt
    49021 taatgtattc atcgatattt tttatcaaca ttttttttat gaccaactgg ttccgacggt
    49081 tccatttgcc acttacttcc agcacatatt tatttagggg caaacgtaag atatattttg
    49141 ccaaatagcg atctttaagc aggccattga tcacacggtc ctcaagctgc aagttgatcc
    49201 cagtcagcat cattggctgt tcttgtaaaa cgtacgtatc aattaaaaga ccttcaaaag
    49261 tttccacaag cgtcttcctt tcttttcaaa gtaacctgaa aacaggcact aattcttcca
    49321 ttttgatatt cgttgaagtg gatgcgatca ttctttcttt tgtccactgt aatctagtat
    49381 aacaaaaaag agcagaagag ccaaaaagaa aaaagagcat cgaattctat aggaagtctc
    49441 attggcacgg cctaaattat tacaaaacat tgattaaaaa aagcccctgc atcgcaggag
    49501 catcccctat atcgttttaa taggtcaatc aaaaagcagt atcaaacaca ttttgtatca
    49561 aatcaggaaa taatagataa gctaagccca gaatcaaaag taccgctaga agaaaccagc
    49621 cgattgttcc tatgaaatac tttaattttt cgaacattgt atcacctcgt tgtcagtata
    49681 tcacggatca gtaaattggg ggtgttaaga atctcctaaa atagacaaaa tttgttctat
    49741 tttcctaaag caaatacttg taagatacag taagtgatac cagaagcaat gaccggtccg
    49801 gcggcgattc ctcttaagaa gacaacacct aaaatcgtgc cgaaaacaag tgcaacagtg
    49861 atttgtggat cagaagcaat caatcctaca cccttggaag ataagacagc cactagccca
    49921 ccgcaaaaaa cagctaccca gccaataggg gatttaaagg cttctaatag atcacgtaga
    49981 ccgatttctc ctgttgcgat agggattaga atagccgctg tgatgatcgt caccccaata
    50041 ttgattcctt tgccttgaag ccaagggaaa aaggaacggg aggctggtat gagcttcata
    50101 atcaaaacaa aagctgccgc tatcatcaga ctttgatttt tagctaaaat tgctacaagt
    50161 aaaataattc ctaaaaaaag ccaactttcc atgaaatata ttcctcactt tcttcgaaac
    50221 aatcataaca tgtttttaga aagttacaaa agtaggaatt catccttcaa gacctattca
    50281 taagctgttt ttttcataaa ataaacaaaa tcataaaaaa acactttgct tatttgacag
    50341 aagacagccg cgctttgtat agtggacaag acttacattt ttttgaagaa tcagaaagat
    50401 caggtaaagg tcttagtaaa cgcaagccat tcagaataac caatattgtg cttccttcgt
    50461 gtcctacaac tccaagaggt agatttaaaa attgcaggaa gttagaagca atcaacaaga
    50521 gaataacaag aatcgaaaaa ataatatttt gtttgatgat ccgccgcatt tttaaagata
    50581 gccgatgact gtagacaaat ttatttaagt cgcttttcat taagacgatg tctgcgatat
    50641 ccatagcggc atctgtccct tgccccatag cgacacctaa agaagcggct gctaaagcag
    50701 gcgcatcatt gactccatca ccaaccatcg catttacttg gtaaagttca ttctcttttt
    50761 tgactagttg tgttttttct tccggagtac agcttgcata gtaatgttca atccctactt
    50821 gttcagcaat ggcctttgct gtgccagaat ggtcgccggt tatcatactt gtatggatgt
    50881 tttgggattt aaagtaggaa attacttgtt gggtatttgc ttttggaata tctagcagac
    50941 ctaaaacagc aattaactgc tgatctttag aaagataaat cacggttttg ccttgatttt
    51001 ccaaacgttc gatcatttcc gcaatctctt tgctgattat catcgtctca ggatcatatg
    51061 cgtgcttgcc aactttccat tgcgcaccta aataggtagt ttgtaatcca aaaccagtaa
    51121 tttcttctat tggtaagtat tggatttctt caggtattgt gcaatcgaaa tattgcaaaa
    51181 tcgcatgagc aagtggatgc gtcgtttttt gttccatagc aacaagaagt tgttgtgcca
    51241 aatccttttc atcaaagaaa aagctgtcag ttacaactgg ttttccttta gtgagcgttc
    51301 ctgttttatc aaaggcaatc gcttttaatt cagaaagctt ttctaaatgg ataccgcctt
    51361 tgattaaaat cccatttttt gcagaatttg aaagagcagc tagagaagct ggtgtagcag
    51421 atgcgacaag cgcacaagga gaagccacaa ctaataatac cattcctcga taaaagcttt
    51481 catcccaact ccaacctagg aaaaagtggg ggagaaggat cattagagga acagcaagca
    51541 aaatcaattt tacataatta ttttcgattc gttcgataaa tgaagctgtt tgagttggcg
    51601 tattctgcgc ttcttctact aattggataa tcttagcaaa gacagtttcg gaactcgttt
    51661 ttgttactcg aatcgtgatg ggatttcctt gattcagcgt tcctgcatac atctcatcgc
    51721 ctaaatattt ttctacaggc acagattcac cgcttaatgc agactcatcg atcgttgcct
    51781 gtgtgctttc taaaaagcca tctatcggaa cagctgctcc tttagcgaca aataccaagt
    51841 tatccacctt tagttgagaa acatctactt cttgcatttg tccattttct tttaataatt
    51901 gggctttttg tggttgaaga ttcatcaaag cagtaatttc tttttgactt ttattagttg
    51961 tgtattcctc taatgcaccg cttaaacaaa agatgaatgt caacattgct ccttcaaagt
    52021 aattaccgat caaacaggca ccaatagcag ctaaagccat caataaatcc acattcagtg
    52081 tccgatcatt ccacaattct ttcaagcctt ccgatgtttg tttatatcca ccgatgataa
    52141 tggcactgat ataaaaaagt ggggtgatgg taagagagaa tcggtcgaag ataaaaccga
    52201 agatcataaa taaaaggcag ccgattgttg ctgcaaaagc ttttttctga ttagtcatcg
    52261 ttattagacc tccttgtcaa aacaaggata gcataataaa aatgtaattg ataataataa
    52321 cagctaaatg agaacgataa tggttatcat ttggtgatta agcttgatgt tgtttttatt
    52381 atttataatg attattatta aagaaaataa aaaaccagaa catttctcaa ataagagaag
    52441 tgttctggtt ttttctacat tgcaataaac caataaccaa tcaaaatgat accaaggata
    52501 atacgatacc agccaaaagc ggtaaagtcg tttttcttca aatagcttag taagaatttg
    52561 atagctaaga cggaaaccac aaaagatacg aatgttccta caagaagaac aacagtttct
    52621 tccattttga atgaattccc ttcagctaaa tatttgacga tcttcaagcc gcttgcgcca
    52681 aacatgacag gaatccctaa gaaaaatgaa aactctgtag cgacaaaacg cgaagcacca
    52741 atcaagatag atcctaggat cgttgcgcca gaacgggatg ttccgggaac aagtgccaag
    52801 acttggaata acccaacaag aagagctgct tggtacgtaa agtcattcag agaagtccaa
    52861 cgaggtgttt tgtttttgtt gcgtttttcg acaataataa aggcaatacc gtaaacgatc
    52921 aaaacaatgg caactggtaa gaacttgtgg aaatttgctt ctaaccaatc atccaaaggc
    52981 aaaccaatga tgatggctgg tatgcaagca acgatcactt taaaccaaag tgtccacgta
    53041 tctttttttt ctaccgttga tttacttgga gaaaatgggt ttaacttgtg aaaataaaga
    53101 acgacgacag ccaagatcgc ccctaattgg ataacgacat tgaacatcga cataaattgt
    53161 gaactggcat ccagtttgat gaattcatct gctaggatca aatgaccagt actactgatg
    53221 ggcagccatt ccgttattcc ttcaataata ccgagaatca ctgctttgat aatatttgca
    53281 aaaaacataa attccttcct tcccaattaa gatacatctt atagtatacc gttatttttt
    53341 gagaaaccca atctgttttt taatattaag aaaaacttga gaaataaagc agataagtac
    53401 acgaagagaa aaaagaagac aaagccctcg ttcagacttt gccttttatg attctctggt
    53461 aaaaattaaa atatccccat tatagaaacg agtcgcgact atgtgttttc ccgttatcga
    53521 tataagacgt atcattgatg ccgtggatag aaaatcgacc gtttgcataa gtgacctttg
    53581 ttacgctgcc atttaaaagc ccagcacgaa caggctgttt aggatcgatc agattaagca
    53641 aaaaggcgat cgtcaaacca tgagatacga ctaaaacatt tccaccacca tttttttcgc
    53701 agtgatgggc gatatcttca aatcctgtcc atacacggtc tcgcaatgtt tcataagttt
    53761 ccgcccaccc agcggtatct aagttgtata cagcattagc aatttgttca aaagaaactt
    53821 ctgtggtaaa catttcatca tatgttttaa aattcaatac acgagggatc acaccccaca
    53881 tttccatgtc atatccacct tcaagagacc cgaaacacca ttctctaatc cttttttcaa
    53941 taaaataagg aatttctttt cccttagaat gttctcctag aataatacgg gcagtttcga
    54001 ttgcacgacc actgtcacta gaataagcaa atgaaaagtc gacatttttt aacccgcgac
    54061 ctaaataatg aatgccttct tgtccttgct ttgtgagggg tgtatcacac cagccttgta
    54121 ctcgttcaat tgtattgaac atcgtttttc cgtgtcgtac gatataaagt gtagtttctg
    54181 tcattttatt ctcctcctaa gtcgttttaa cgattgaaaa aaggatttgt ccttttttcc
    54241 tgttcaatcg tcgttgcatc gccatgtcct ggatagactg caaattcatc aggtaataca
    54301 aacagctggg tccgaatact atgaagtaat tgttctaaat tccctgtata cagatcggtt
    54361 ctaccgatac ttcctctaaa cagggcgtcg ccagaaacga caaaatcatc aaaaataaag
    54421 ctgacgcttc ctatagaatg ccctggggta gggacgacgc gaaaagacat gtttcctaaa
    54481 gtataagttt tcatttcaaa ttcatattct gcaggcgaga caataacatc agcaatatca
    54541 tcatgtctac cgagtccaga aagattcaaa atcggatcac ctagccattt ttgctctagt
    54601 gggctgacat aaactgggat ttgataatac gcgcgtaaag gttccactgc accgatatga
    54661 tcgtagtgag tatgggtaag caaaatcgct accggctgtt ggtttgtttt tttgatttct
    54721 tgtttgattc gttccgcatc ttctccaggg tcaatgatca aaagtgcttc ttcgttgtag
    54781 accaaataac agttttcttc aatcattcct gtttttaatc tttcgatatg catgtgcatt
    54841 cctccttgat agccaaaact tctttcatcc attagtataa cgcattcatt gctaggaaac
    54901 aaaaacaggt acttatttct ctttacttat ctgaattatc agactatatg aaaagtattt
    54961 ggatattcta aagagaagga aagtaagttt tcatagcatt ttaatatgtc cttgttacat
    55021 tagattcatc caaaaatcca aattctatat cctatatccc tgcctaatca gcagggtgtt
    55081 tttttatgtt tggaaagaga gctctttttg ctaaactagg ttttttcagg taatcttaga
    55141 gagaaagagg tggtggaaat gatcaaacag tcaaaaatat ctgtgcggca cttagtagaa
    55201 tttattttgc gacgtggaag tatcgacaat cgtaaaaaaa gtaaccatac tgcattagaa
    55261 ggagcgagaa tccaccgcaa gctccaaaaa gatgcgggag aaaactatga aaaagaagtc
    55321 tttttaaaaa caacagttca attagatgaa tattacctga tcgttgaagg ccgtgcagac
    55381 ggtattttca aaagagacgg tatttattat atagatgaaa tcaaaacctc cgaaccacga
    55441 tttgaagatt tagaaccaga acaagtggaa cttttctttc atcaagcaag ggtgtatgcc
    55501 tatatctata gtcaagaaca tgatttacaa gaaataaatc tgcaattgac ttacttccag
    55561 acggcagaag aagtgatcac gagaaaggtt gaacatcaga caagagagca gttagaaact
    55621 ttttttaaaa agctgactga agattataaa gaatggcttg tttttcaaga aaactggcgc
    55681 actgtacgca atgcctcttt gatggctttg aaattccccc atgatgagta taggaaaggt
    55741 cagcgtgaac tagcggtagc tgcttataaa acgatccgta cgaaacagaa attgtttgta
    55801 gaagcaccta ccggaacagg aaaaacaatc tctacgttat tccccgcttt gaaagctgta
    55861 ggggaagaag agggagaaaa gatcttttat ctaacggcta aaacaataac tagacaagta
    55921 gctgaagatg ctatgacagc attaaaagat acaggagctg aagtaaaaag tgtcactttg
    55981 acggcgaaag acaagatctg ctttttagat gagacgacct gtaatccaga tcagtgccca
    56041 tatgccaatg gttattacaa tcggattaat gaaggtttat gggatctttt gaatcatgag
    56101 aatcagatca ctcgtgaagt catcgaaact tatgcaagaa agcatacact ttgtcctttc
    56161 gaactatcat tagatgtcag tatctggtgt gacgtaatca ttggggatta caattattta
    56221 tttgatccaa ctgtttattt aagacgtttt tttgaagatg aaaaaaacga ggactatctg
    56281 tttttgattg acgaagcaca taatttggtg aatcgttccc gagagatgta ttcggcagaa
    56341 ctatcttatg aaaaaacgaa acgaagtaag gaagctatac caaaggaatt caaaaaactt
    56401 catcgccgtt tcaacaaact attaaaagaa tttgattcga tccgagaaat agcaaaagaa
    56461 gatcattggg attatcatca tcaaaaagca ccggctgaat ctttagtaaa ggcaggttat
    56521 caattaagcg aaaaaattaa agaatggctg gcagaatttc ctgagcaccc atcacaagaa
    56581 caattgcttc cttattattt tgatttgctt cattttttga aggtcagtga attttatgat
    56641 gatcactacg aaacaacagt cgaaaaaacg tatcgcgatc tgatagtaaa agagttttgt
    56701 attgatccaa gcttgtttct tgagcagtcg ttggataaag gaaaaagcag tattcttttt
    56761 tctgctagtt tttcaccact ctcttattat caggaaacac tggggggaca aaaaagtctg
    56821 gcttacaaac tgccgagtcc tttcccagaa ggaaaccagc aagttttcat cgcaaattac
    56881 ctagagacga cttatcgaaa aagggaacac agtctggcaa aattagtaga gacgattcat
    56941 gcttttgctg atggaaaggt cgggaattat ttcgttttct ttccttctta tcaatattta
    57001 gatcttgcgg tggaagcatt cagacagcaa tatcccgaca gcaatgtgct aatccaagaa
    57061 acggacatga atgaggaaga acgcgaacga tttttaacaa aatttcaaac aaatcccgct
    57121 gaaacattga ttggattttg cgtacttggc gggatttttt cagaaggaat cgatttgaga
    57181 ggggaccgat tgatcggcag tatgatcgta ggtgtaggtt tgccgcagat gaatcatgag
    57241 caggaactga tcaaatcata ttatgatgag aaggaacacc ttggatttgc ttacgcttat
    57301 cagcttcctg gaatgaacaa agtcttgcaa gctggtggtc gagtgattcg tggcatggcg
    57361 gatcaaggaa tcgttgtatt ggcagatcaa cgattttcta gtttttctta tcgacgttta
    57421 ttcccacaac attggcaaac agcaagagaa gtacgaagtg ttggggaatt ggaagaagga
    57481 atacagcgtt tttggttatc aaaagaagca gtaaatcaaa aaaacgagga atgacagacg
    57541 tcagcctcgt tttttgatta acgatagtta gtgaattgca actcgattgg taagtcaagt
    57601 ttacgtaata aagcaatcac agcttgtaga tcatcacggt tcttacctgt cactctaatc
    57661 tgatcttctt ggatttgtgc ttttactttc agtttttcat ttttgatagc tgtagtgatt
    57721 ttcttcgcgt tttcacgatc gattccgttg accaaatcgg cagtttgtcg agctttgcca
    57781 cctagagcgt gttctgattc ggaaaaatgg atatttttga ttggcacatt tcttttgatc
    57841 agcttaccaa ataatacatc tttgatctgt tcgattttga aatcatcatc gctcaataca
    57901 actagattgc tgttctctaa tttgatttct actgtagaat ccttgaagtc aaagcgattg
    57961 gacaattctt ttgttgtttg ctgaatcgca ttttttactt cttctgtatt gacttctgat
    58021 acaatgtcga agctagcatc ttttgccata ggaaccctcc tgatatacat ataaatattt
    58081 accatacatc tatcttatca taggattagg gcagattctt acctgtttgc taaaattctt
    58141 ctcatttgag ttcgaagtat tttattttaa tagataaact gttattctta catttggaat
    58201 accaaagtag gggagaggtg cttgtgagta aaattatgac tgcgtatcat aaaaatgaaa
    58261 gattaaagaa aatagtggtt attttgataa ccggattgac cgctgcggtc gctttaaatt
    58321 attttttgat tccagccaat gtcttttctg cagggatgaa tgggatcgct caaatcattt
    58381 cctcgctttt atatgaatgg tttcatatca agatagacac aggaacattt atttttcttt
    58441 tgaatatccc tgtgtttgta ttagggtttc tcaaagtagg aaaacgagca acgatcctta
    58501 gttttgtgaa tgttgtatgt gtatcggtga tgacgatgct gcttccagtc ggacagatca
    58561 ctgataatat tttgatgaat gccctagtag gcggtgtttt attaggtctt ggcgtaggat
    58621 tatctttaaa aatgggcttt acaactggtg ggatggatat catctctctt gtactttcac
    58681 aaacaactgg aaaaacagtc ggaaactaca tgctgattct aaatggtatc attgtagtca
    58741 tcgcaggctt cttctttaac tgggaaagtg ccttgtatac gattatttcc atttatgcaa
    58801 tgactcaagt aattgatgcc atccacacga gtcatcaaaa agtaacagca atgatcgtta
    58861 ccgtcaagcc agaagaggta acagaagaac tagcaaaacg gatggtacgt ggaatgacat
    58921 tactgccgtc tgtcggtggc tattcaaaaa aacaagggaa catgatcatg atggtcatca
    58981 cccgctacga aatgtatgat cttgatcaga tcgttcatga aatcgacgac gatgcattta
    59041 tcaatatttt accaactcat tcagtatttg gccggtttgc aaatgaaaac gaacaaaaaa
    59101 tgtatcgaac aactggcgta ttgccagaaa taaaaaatcg ttcacaaaaa aaatgaggaa
    59161 tcaggtttat tttagaataa atttaatcta ttacatctaa taagaacatt tttataaatt
    59221 taaacgagaa tcttacttct aaattctcat ttacaagcag ctaaaaaaag agtatgataa
    59281 ataaaaatcg tgttaaggag tgtcgtacga tgagcgaagc aaaccaagaa cggtctggac
    59341 aagaaataga actaatcaaa gaacgtattc ttgctgcctt ggaaatggtg attgatcctg
    59401 aattaggaat cgacatcgtc aatttaggct tgatttatga tatagaattc aatcctgaaa
    59461 atggagaaac agtcattaag atgactctaa caactatggg ctgtccatta gcagatattt
    59521 taacagaatc tatccatgac gcattaaaag aagtgccaga agtaacgaaa gcagaagtca
    59581 aactagtctg gtatccagca tggacgacag ataagatgag ccgttatgca cggattgcgt
    59641 tggggatacg atagaaatct tggctgacta gctatgagaa gcaaatagga aaaacaaaaa
    59701 agccttttat cctttctaga agaaaagaga taaaaggttt ctttgtttat aaaattttgt
    59761 ctgctatatt ataagttaat taaataaatg tgttctattg ataaaggaca ttcaaatccc
    59821 tttccttttg gaatccttct tttttacatc agtttgattt tcgtatagta ttctttctca
    59881 tcttcacgat aaatcgcagc cccatttttt tgttgtgctt taagactgcc aagatttttt
    59941 ttatttacag acaaaagtgc ctcatcaatg ccgatttttt ttgcctcttg tagtactaat
    60001 gctaatcctt gtgtggcata tcctttttta cgataattag gggagatgcc gtaaccaata
    60061 tggccagcgc cgtttcttaa tgtttcgttc agtttatggc gcaaattaaa aattcctaca
    60121 tactcatgtt catcactttc taaaataaag acggttgcgg gaacgtaact ctcaggaaga
    60181 tcgattccta aagacgtttt ttcgcatttt tttacataat ctaaaaattc agcaaatgta
    60241 tagccataag cattgttgat aaatccactc tcatttggtc caaagctagt ttgtagctga
    60301 taagctttct ttaaatctgc ttcccatagt ttgatcagtt tcatcgtatt cacctcttta
    60361 agtaacctta ttcatttgtt ttctactata gcactattgt tgtaaatagc catgcctatt
    60421 tttatttatt gtgtcatatc gtattaagaa tcatcgaaca atacaaatat gaattacaat
    60481 aaaaaaatta tttgaagttc gttcattcgt tacttatgat ctctagaaga aagaaaacgt
    60541 gaattacttc agcgtctaga attccagaag gatagtaatc aacagaagaa ataatcaata
    60601 tccaaatgaa agaagatagc tgaatcgaga aaaagaggaa aaaagaaatg aagaaaaaaa
    60661 taaaatagtt actaatccca gagtcgttcg tttaacattg aaatcgatca tatggataaa
    60721 acagattttt tcaccaaccc tcaatagatg atggagttgc tcggatgaat tatttgtgta
    60781 gatggcataa gggagggcgt acagaaatga aaaagaacaa aaatatgttc ttgacaaaaa
    60841 acacatgtaa tcctaaacta aaagatgtga tgcggctatg gcggaattgg cagacgcgct
    60901 agcttcaggc gctagtgagg gtgacctcgt ggaagttcga gtcttcttag ccgcataatt
    60961 tgttttttta taaagagaag gtacacctgg agcgatgaga aagaaaataa catattatct
    61021 aaaagaatat aggaaaaatt ttaaacaacg gaaccagatt caaataaatc aaaaaaaatt
    61081 tgtgtgaagg tgggacagtt taaaacctaa tagattgatt caaatagtag atttatagat
    61141 tctgatacaa gaaatactgg caaacgatag ttaaggaata aagactaaac ttaaactcaa
    61201 aaagaggtca tgcgaaagaa taaatcgcat gacctcttac tatattttga atgtgtttaa
    61261 acgttcaaat aatgaatctt agtaccaacc gtttgcttcc cagaatgctt tcgccgcttc
    61321 ccaagaacca taacgtgaag taacatattg ttctgctact ctttcttggt ttgcagcaga
    61381 gtagtcacca tttaagtaag aagaatctaa ttggtaacgg ccgatgtaac gtccgttcgt
    61441 tgctgtgtaa gaaccgcttg attctttttg tgcgatccat tcttttgcag agcttgtact
    61501 tgctggagta gcagcagttt ctgttacagc aggagcaggt tgtgtttcag caacaggcgc
    61561 tgcttgtgtt tccgtttgaa ccgtttcttg tacaacaggt tgttcagctt gaacaggttc
    61621 agcttggact ggtgcttctt gaacggctgc ttgaggttca gcagctgctt gtgcagagcc
    61681 ttctgttggg attgttaatt gttgtcctga gta
//
LOCUS       DAXQKX010000010        61534 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.010, whole genome shotgun sequence.
ACCESSION   DAXQKX010000010 DAXQKX010000000
VERSION     DAXQKX010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 61534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.010"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(59..187)
                     /locus_tag="ACF3MF_000694"
     CDS             complement(59..187)
                     /locus_tag="ACF3MF_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFE3926718.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="ACF3MF_000695"
     CDS             complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="ACF3MF_000695"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFE3926719.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(1674..2729)
                     /locus_tag="ACF3MF_000696"
     CDS             complement(1674..2729)
                     /locus_tag="ACF3MF_000696"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFE3926720.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="ACF3MF_000697"
     CDS             complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="ACF3MF_000697"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HFE3926721.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="ACF3MF_000698"
     CDS             complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="ACF3MF_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HFE3926722.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKATFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="ACF3MF_000699"
     CDS             complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="ACF3MF_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HFE3926723.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="ACF3MF_000700"
     CDS             complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="ACF3MF_000700"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HFE3926724.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTVKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="ACF3MF_000701"
     CDS             complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="ACF3MF_000701"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HFE3926725.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLANPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            10491..12050
                     /locus_tag="ACF3MF_000702"
     CDS             10491..12050
                     /locus_tag="ACF3MF_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HFE3926726.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQKVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(12161..14092)
                     /locus_tag="ACF3MF_000703"
     CDS             complement(12161..14092)
                     /locus_tag="ACF3MF_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HFE3926727.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAAAEA"
     gene            complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="ACF3MF_000704"
     CDS             complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="ACF3MF_000704"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HFE3926728.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(15021..15773)
                     /locus_tag="ACF3MF_000705"
     CDS             complement(15021..15773)
                     /locus_tag="ACF3MF_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFE3926729.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLFNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(15932..16141)
                     /locus_tag="ACF3MF_000706"
     CDS             complement(15932..16141)
                     /locus_tag="ACF3MF_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926730.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(16152..17480)
                     /locus_tag="ACF3MF_000707"
     CDS             complement(16152..17480)
                     /locus_tag="ACF3MF_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926731.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            17616..17771
                     /locus_tag="ACF3MF_000708"
     CDS             17616..17771
                     /locus_tag="ACF3MF_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HFE3926732.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(17845..18432)
                     /gene="yihA"
                     /locus_tag="ACF3MF_000709"
     CDS             complement(17845..18432)
                     /gene="yihA"
                     /locus_tag="ACF3MF_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HFE3926733.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="ACF3MF_000710"
     CDS             complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="ACF3MF_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HFE3926734.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVERAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(20012..21301)
                     /gene="tig"
                     /locus_tag="ACF3MF_000711"
     CDS             complement(20012..21301)
                     /gene="tig"
                     /locus_tag="ACF3MF_000711"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HFE3926735.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(21455..22387)
                     /locus_tag="ACF3MF_000712"
     CDS             complement(21455..22387)
                     /locus_tag="ACF3MF_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926736.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLNEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(22544..23203)
                     /locus_tag="ACF3MF_000713"
     CDS             complement(22544..23203)
                     /locus_tag="ACF3MF_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HFE3926737.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSIYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAIFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="ACF3MF_000714"
     CDS             complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="ACF3MF_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HFE3926738.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELASNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAMR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(24244..24534)
                     /locus_tag="ACF3MF_000715"
     CDS             complement(24244..24534)
                     /locus_tag="ACF3MF_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926739.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAEAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            24944..26749
                     /gene="glmS"
                     /locus_tag="ACF3MF_000716"
     CDS             24944..26749
                     /gene="glmS"
                     /locus_tag="ACF3MF_000716"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HFE3926740.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDSSDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(26821..28176)
                     /gene="glmM"
                     /locus_tag="ACF3MF_000717"
     CDS             complement(26821..28176)
                     /gene="glmM"
                     /locus_tag="ACF3MF_000717"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HFE3926741.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(28200..29369)
                     /locus_tag="ACF3MF_000718"
     CDS             complement(28200..29369)
                     /locus_tag="ACF3MF_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HFE3926742.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(29366..30253)
                     /gene="cdaA"
                     /locus_tag="ACF3MF_000719"
     CDS             complement(29366..30253)
                     /gene="cdaA"
                     /locus_tag="ACF3MF_000719"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HFE3926743.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="ACF3MF_000720"
     CDS             complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="ACF3MF_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HFE3926744.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIVPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPAMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLENANPN
                     LAKALFEKTIQDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARAERRKKMEQATKEKKEK"
     gene            34320..34841
                     /locus_tag="ACF3MF_000721"
     CDS             34320..34841
                     /locus_tag="ACF3MF_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HFE3926745.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLSCPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(35540..36105)
                     /locus_tag="ACF3MF_000722"
                     /pseudo
     CDS             complement(35540..36105)
                     /locus_tag="ACF3MF_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(36284..36940)
                     /locus_tag="ACF3MF_000723"
     CDS             complement(36284..36940)
                     /locus_tag="ACF3MF_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926746.1"
                     /translation="MRFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLRAGLITFIS
                     IVGFFLFTVIVFIWRTPAPPLPEITYGEFPFRLEYELNEELHVIEDTLIVEFDGFGMN
                     EGIGRYRRWTSRLASGEDLVLLLEVSDNKQIFYFPGPANYYMGDRLNGYNHTFPSASF
                     IERERGITRRDILHDKELLEQFGPLDQNTINEEELLNQYNIRLVNWEISEPIVNNFGD
                     "
     gene            complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="ACF3MF_000724"
     CDS             complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="ACF3MF_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HFE3926747.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(38477..39475)
                     /gene="yvcK"
                     /locus_tag="ACF3MF_000725"
     CDS             complement(38477..39475)
                     /gene="yvcK"
                     /locus_tag="ACF3MF_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine diphosphate-N-acetylglucosamine-binding
                     protein YvcK"
                     /protein_id="HFE3926748.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAIDR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="ACF3MF_000726"
     CDS             complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="ACF3MF_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HFE3926749.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(40491..41222)
                     /locus_tag="ACF3MF_000727"
     CDS             complement(40491..41222)
                     /locus_tag="ACF3MF_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HFE3926750.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLQPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTVLQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSKALDTASEK"
     gene            complement(41226..42491)
                     /locus_tag="ACF3MF_000728"
     CDS             complement(41226..42491)
                     /locus_tag="ACF3MF_000728"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HFE3926751.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="ACF3MF_000729"
     CDS             complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="ACF3MF_000729"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HFE3926752.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQDIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="ACF3MF_000730"
     CDS             complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="ACF3MF_000730"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HFE3926753.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQVRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKNAAKALDFETAANVRDMILELKASK"
     gene            47833..49335
                     /locus_tag="ACF3MF_000731"
     CDS             47833..49335
                     /locus_tag="ACF3MF_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HFE3926754.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            49337..50074
                     /locus_tag="ACF3MF_000732"
     CDS             49337..50074
                     /locus_tag="ACF3MF_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFE3926755.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="ACF3MF_000733"
     CDS             complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="ACF3MF_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HFE3926756.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="ACF3MF_000734"
     CDS             complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="ACF3MF_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HFE3926757.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="ACF3MF_000735"
     CDS             complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="ACF3MF_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HFE3926758.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="ACF3MF_000736"
     CDS             complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="ACF3MF_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HFE3926759.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEEKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            complement(55574..56740)
                     /gene="hemW"
                     /locus_tag="ACF3MF_000737"
     CDS             complement(55574..56740)
                     /gene="hemW"
                     /locus_tag="ACF3MF_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HFE3926760.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMRLMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYRDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            complement(56756..56983)
                     /locus_tag="ACF3MF_000738"
     CDS             complement(56756..56983)
                     /locus_tag="ACF3MF_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HFE3926761.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            complement(57303..57626)
                     /gene="relB"
                     /locus_tag="ACF3MF_000739"
     CDS             complement(57303..57626)
                     /gene="relB"
                     /locus_tag="ACF3MF_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HFE3926762.1"
                     /translation="MRFFKRGNYRAMITVRVSDAKKEWLSYMAEFYGITLSELLKNYS
                     MEQLEDEYNRQTAEIAHKHWIRSGKTTVFMEESLMNLVGWNDLPFKIHARNSEAALIG
                     KYVYW"
     gene            complement(57969..58415)
                     /locus_tag="ACF3MF_000740"
     CDS             complement(57969..58415)
                     /locus_tag="ACF3MF_000740"
                     /inference="COORDINATES: protein motif:HMM:NF013964.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HFE3926763.1"
                     /translation="MKIKIYNQEENQTRHIRNLSNAKLEEEARKVSNYNKKMAAKYVN
                     EEEFCFSKTKIYKRNPFVSEYVKRLAKGICQLCQEKGPFIKDGVPYLHCHHIEYLSQG
                     GKDVIENCIALCPNCHARIHELELPDDKEKLLKIVEKRENSFSKIP"
     gene            complement(58396..58992)
                     /locus_tag="ACF3MF_000741"
     CDS             complement(58396..58992)
                     /locus_tag="ACF3MF_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HFE3926764.1"
                     /translation="MNPTLITKKELLKKLDISTGVLANLIRNGMPKEGEMFNLDKIIT
                     WRENWSKNILGELEVGRVYTNKEISEKFKCSKQGGMRRSHQTNTLVLFSDQTGSNVYK
                     DKWLNGILQYTGMGLKGDQVLDKNQNKVLANSKSNFVKIHLFETFKPKEHTYLGEVYL
                     AGQIYTVNEKDSSGNSRKVYKFPLALINQEQLIEDKDI"
     gene            complement(59476..59637)
                     /locus_tag="ACF3MF_000742"
     CDS             complement(59476..59637)
                     /locus_tag="ACF3MF_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926765.1"
                     /translation="MTEKEQVQQIVKKYNKSIADLSENASAKEFKTVMNYVADEANRK
                     QRKLVGLDK"
     gene            complement(59630..60304)
                     /locus_tag="ACF3MF_000743"
                     /pseudo
     CDS             complement(59630..60304)
                     /locus_tag="ACF3MF_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
     gene            60827..61434
                     /locus_tag="ACF3MF_000744"
                     /pseudo
     CDS             60827..61434
                     /locus_tag="ACF3MF_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313657.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase family
                     protein"
BASE COUNT        17077 a        13212 c        10646 g        20599 t
ORIGIN      
        1 taaaaagact aagaaacaat aacaaaagtt aacacttctt agtctttctt tagcacgtct
       61 atttattaaa gattttaggg ccttttctca tgtttttacg atcattctta ggtgtttcca
      121 tttgtttgga tcggcctcca ccttgtttct ttttgatcaa ttctttcatt ttttcttttt
      181 ggtccatttt tattctcctt taacgaatga agcgactaat tcgatatgat gggtttgcgg
      241 gaaaagatct acaggctgaa ctttcttcac ggcataacct gcttctgcaa ataacttagc
      301 atctcttgca aaagttgccg gattacatga gatatagacg attcgttctg gtgacatttc
      361 gattgctgat tcaataaaat gatgatctaa tccttttcgt ggagggtcaa ctacgatcac
      421 agatggtttg atcccttttt cttgccattt tttcataact ttttctgctt ttccgacttc
      481 ataatgaaca ttttcgattt tattatttaa agcattgaac tgtgcatctt caattgcttc
      541 tggaataact tccatcccat acaccttatc cactctgtct gctaaagaca agccaatcgt
      601 acctattcct gaataagcgt cgatcacaat gtctttttta tctaactcgg caaactcgat
      661 ggctgtttgg tacagatact ctgcttgttg agtatttact tgataaaatg actttgctga
      721 gattcgatag gtttttccta atagctgatc ttcgatatag tctctgccat ataaaacttt
      781 ttctttgtct cctaaaatca catttgtttt ttcttcattg atattttgga tgaccgaaac
      841 cacttctggc aattcttcat gaatagcttc agcaatttcc ttggatttaa agaatttttc
      901 tttacgagta actaaaacga ccatcatttc atgggaataa tgaccacgac ggataatgat
      961 gtgacgaagc tgtccttcat ttttttcttc attatatcct cgtacttgga accgttgcaa
     1021 gatatctctg actactttga ttgcttgatc gatgacagga tcttggatat aaaaatcttc
     1081 gatagggact agatcatggc tattcttttt gtaaaaaccg gtggctaact gtccatcgat
     1141 acggcgaaca gggatctgtg ctttattacg gtagccgaat ggttctgcca ttccgaccgt
     1201 tggaagtaca ggaacttctg gcatcttagc aatcttcgcc attacatgct ctacttgttt
     1261 ttgtttgaag acaagctgtt gttcatactt caaatgggct aaaggtgcga tacctatgcg
     1321 aagtaatgca ttgttttcta caggctgacg atcaggtgat tgtgtaataa atgtttcgac
     1381 ttttccatat ccaaacttat tgcctgcttt tactactagt atttctactt cttctccagg
     1441 gagtgcattt tcgataaata atggataacc atcgattttt gctaccccca ttccttcata
     1501 actcaagtcg acgatttcga ctgtatatcg ttcgtttttc tttactattt gctgttctgt
     1561 catattttgc tcctttaagc ctatttttca atcctactga actctactat aaatcagcta
     1621 attacacaac taaaaccggc actgacctta ctacgttcag caccggcttt tgattaattc
     1681 ttttgattag gtgtttcgtc tgctattttt ccgtcaccgt cgatatcttc atccgttaaa
     1741 cgttcgactt cttttacgaa ttctttgctg acaacctcta attcttcttc atctgtacct
     1801 gtgattgctt catcaggaat ctgatcggta ttggcaaaga actcaatgtg ttgatgaaga
     1861 ttttggaaat gcatcggtgc ttccccgccg tattcaccat ctaagttgat cattactggt
     1921 cgattgatat catcttctgt ttcaacgaac aaactgcttg ttttggtata gattattctt
     1981 ggatcatcga catgtcgacc gccattcagc atgagtgctg caatatgcaa gatctcaaag
     2041 atatttgctg tcttcacaat gattaaagaa aacttcccat catccaattt ggcatctggc
     2101 gcgatctgtt cgaatcctcc aacagagttc gtcagcccta ggaaaaacat cgaagcattt
     2161 ccgatatatt ccccttcatc atacttcaag cgcattttga ttggctttac tcgagggagc
     2221 atctctgctc ctttcgcaag ataagcaaga taaccaaaaa tactctttag ttctgatgga
     2281 acttcataag tcaattctgt caaatagcca cctgcagcga tattgatgaa gtaactgtta
     2341 tcagaaaggc cgatgtccat ttttacggtt tggtgttttt ttatcacttc tgctgctgct
     2401 ttaatattat ctctaggaat ttttaatgct cgagcatagt cgttcgttgt accagctggg
     2461 atgatggcca ttttaggacg gtgttcaagc ggagcgattc cattaaccac ttcgttgatt
     2521 gtgccatcgc caccagctgc cactactaga tcaaaaccta gttctgcgac tctacatgct
     2581 tcattcttgg ctgaatctgg ttctggtgta gttgcatagg cgctggcttc aaatcctgct
     2641 tcttctaatg cctgtaggat atccgccaaa ttttttttca ataattcttt tcccgaggtg
     2701 gggttataaa ttacgcgtgc ttttttcatt ttcagcctct atcgtttcgc taattcatct
     2761 ttaagtagct tattcacgac accaggattt gcttgtcctt tagttgcttt catgatttga
     2821 ccgactagga agccaaccgc acgatctttt ccatttttga aatcatcgac agattgttgg
     2881 ttgttatcca aaatttcatt aatgattggc agtagtttgt tcggatcaga taattgcacc
     2941 caaccatttt tttcaactac ttcttgggct tctccgccat ttgtgatcaa ttcacggaag
     3001 acttttttgg cgatttttga gctgatcgtt ccatcggcga tcaaacgaat cattcctgct
     3061 aagttctcag gtgtcaattt tgtctcagct aattccagtt tctcactgtt caagtaagca
     3121 gaaacttcac ccatcaacca gttagatgct tgcttggcat ctgcaccatt ttccaaaaca
     3181 gcttcaaaaa aatcagacat ttcttttgta agtgtcaata ccattgcgtc atactctgga
     3241 agtccaaact cacggatata gcgttcgcga cgagaagctg gcatctcagg caaactagct
     3301 tttacttttt gaatccattc gtcatcgatc acgaatttcg ggatatcagg ctctgggaag
     3361 taacgataat cactagaccc ttctttgaca cgcatcaaaa ctgttttatt cgttgtttcg
     3421 tcaaaacggc gtgtttcttg ttggatttct cctcctgaaa gaagaacttt tgcttgacgt
     3481 ttttcttcaa aagctaaacc ttttttcacg aaagataaag agttcaagtt tttcaattct
     3541 gctttcgtac cgaactcttc ttgtccataa gggcgaagag aaatattggc atcacagcgc
     3601 atagagcctt cttccatttt cacatcgctg acttctgtaa attggataat tgatcgcaat
     3661 gcttctagat aagcgtatgc ttcttctggt gaacgcatat cagcttcaga aacgatttcg
     3721 atcaaaggcg tgccttgtcg gttcaaatca acgtaagaat aaccgccaat accatgcatg
     3781 ttttttccag catcttcttc taaatggaca cgttcgatcc ggattttttt ctttttacct
     3841 tctacttcga tttcgatcca tccgtcatga ccgattggtt gatcaaattg ggaaatttga
     3901 tatgcttttg gattatctgg gtaaaagtaa tttttccggt caaaatgagt atctttagag
     3961 atttcacagt ttaatgccaa agctgctttc atcccgaatt ccagcgcagc tttattcatt
     4021 actggcagca cgcctggata accccagtcg atcacgtttg tattgctgtt tggttctgca
     4081 ccaaaatgag ctggcgctgg agagaaaatt tttgagttgg tttttaactc gacgtggact
     4141 tctagtccaa tgactgtttc aaaattcatt cgtctttccc tcctaaaata gctggttgtt
     4201 gtttatggaa ttctgttgct tgttcaaacg catatgccgc ttgatacatc gttttttcat
     4261 caaaataatt accgatgatc tgcaatccaa ctggtaatcc ttctgataaa cctgccggta
     4321 cagacatacc tggaagtcca gccaagttga cagggatcgt taagatgtca ctcatgtaca
     4381 ttgtgattgg atcgttaatg ttctcaccga ttccgaatgc aactgttggt gaagatggcc
     4441 cgatgatcaa gtcataatct gcaaagactt tttcaaaatc tcgtttgatc aatgtacgga
     4501 cttgtcccgc ttttttgaag taagcgtcat aataaccagc acttaaggag aatgtaccta
     4561 acatgatacg gcgttttact tcttcaccga atccttctga acgtgagttg acatatacat
     4621 catctaatga tttcacattt tctgagcgat aaccgtagcg gataccatcg aatcgttgca
     4681 agttggaact tgcttctgat gaggcaatga tataataaac agccacaccg tattttgaat
     4741 gaggcaagct gacttcttcc acaacagcac ctaatgaacg gaatgtttct gctgctttca
     4801 atacagcttc ttttacgcca ggggccacac cttcgcctaa gtattcttta ggtaaagcaa
     4861 tcttcattcc tttgatgtcg cctgtcagtc cctctgcaaa atcaggaact gaaacgcctg
     4921 aagaagtacc gtctttttcg tcataaccgc tgatagctgt caatgctaat gcattatctt
     4981 tcaccgtacg ggtcattggt ccgatttggt caagagatga agcaaaggca atcaaaccaa
     5041 aacgtgagac acggccataa gtaggtttca tccctacgat gccgttaaaa gctgctggtt
     5101 ggcggatact tcccccagta tcactaccta aagaaactgg aatttgtcca gctgcaactg
     5161 ctgctgcaga accaccagaa gagccaccag gtacttttgt tgggtcccaa gcattttttg
     5221 ttttcttgaa ataagaagtt tctgtacttc cacccatagc aaattcatcc atgtttagct
     5281 taccaacagg gatcatatct gcttgataga ttttatccat gaccgttgca tcataaattg
     5341 gttcaaaatt gtaaaggatc ttagatgcag cggttgtcaa gatatctttt gttacgatat
     5401 tatccttgat accaattgga ataccagcaa ggacgttgct ttcatcaatc cctttttcat
     5461 ctaaagcttt tgcctgttcc aatgcttttt cttcgttcaa tgtaatgaat gcttcgacct
     5521 caggctctgt ttctttgatt cgttcaaatg ttgcttttgt caaatcttgt acagtgattt
     5581 ctttcgatac aagcatatga tgcagttctt ctagagaacg attgtgtaat tctgtcatta
     5641 tgcgccagcc tccccattat cgatgattgc gggtactttg ataaagccgt cttctgtttc
     5701 cggcacattt ttcaataatt catcgcggtt ccatccagct tgcgcccgat cttgtcgcat
     5761 cacgtttact gtttcaacca cattcgacgt aaatggaaca ccttctgtat ctacttcttc
     5821 cagcatttca accatatcga tgattttacc taattggtcg gtaaaacttg caagttcttc
     5881 atctgcgaac gcaagttttg ctaatttggc aacgtgtttc acttgttctt cactaatcgc
     5941 catactaccc cttctttcta aacgagttaa aaactttgct ctctatttta acacaagagt
     6001 gccgtgtctg aaattgttta ttgaaatttg tctgaaaaaa ctcatttttc attcttctac
     6061 tgagcgactt ttagccaatg catctgccat ttgatcttct gtccaaactt cgattcctaa
     6121 ttcttgtgct ttggtcagct tgctgccagc atcttctcct gctaccacga tatccgtttt
     6181 tttcgatacg ctaccagtca ctttcccgcc aagattttcg atcgtctctt ttgcttcttc
     6241 acgagtaaat cgtgttagtt taccagtaag gactactgtt ttttctttaa aaggagactc
     6301 gacttcttgc aattgggcat ttcgaagccc tttgtattcg aaattgacgc ctgcttgttt
     6361 taattcattc atcaattcat ggacttcttc gttactgaaa taagtgacta cactgtcggc
     6421 aatgatatca ccgatcgtat caagcgcaat aatcgactca tagtcacttt tactcaatgt
     6481 ttctagatca ccgaaatgtt ctgctaaaat ttttgctgct ttcgctccga catgtcggat
     6541 tcctaacccg aaaatcaacc gctcgaccga attatctttg ctgttgtcga ttgctgtcaa
     6601 aatattattt gctgattttt cttttatttt gtccaacgtc aataactctt cttctgtcaa
     6661 tttgtaaaga tcagcaacat ctgctactag ttttttatca tacatctgtt ctagtacgcg
     6721 cggccccaac ccatcgatat tcatcgcatt tcttgaaaca aagtggttca aaccttcttt
     6781 catttgagca gggcatttag gattgatgca ccgtaaggct acttcttcat ccaaatggac
     6841 aagttcactt ccacaaactg gacaatgtgt aggcaattgg tattcttcgc tgtctttagg
     6901 tcgtttatct aacacgactt gcgaaacttc tgggatgatg tctcccgctt tataaatcag
     6961 aactgtatct ttcaagcgga tatccttcaa cttaatataa tcaccgttat gcaggctggc
     7021 acggcttact gtcgttcctg ctactcggac tggtgtcatg atagctgttg gcgttactac
     7081 ccctgttcga ccgactgtcc attcgatgtt ttcgattagc gtttcaactt cttctggcgg
     7141 aaacttgtaa gctgctgccc atctcggtgc tttgacagta aaaccaagtt gatcttgtag
     7201 cgagaattca ttcactttga tgacgattcc atcgatttca tagggcaaat ccacacgttt
     7261 gtcatgatat tcttcaatgt atgaccacac ttcatcaatc gaatgacata gacgtttttc
     7321 ccgattcgtg tggaatccaa ttttttctag ctcttctagc gcatcatact gggtttttgc
     7381 ttgcatagga ccgaaatcag ctactgtgta taaaaaagtg tccagatttc ttttcgctgt
     7441 gattttagaa tctaactgac gcaaagaacc agctgcggcg ttccgaggat tcgcaaagat
     7501 atcttttccc tctgcttctc tgtcttggtt caattggaca aatgaccgtt ttggcatgaa
     7561 acattcgcct cttacttcga tgttcattgg ttcttttaat ttgattggga ccgaccggac
     7621 agtttttagg ttttcagtga tgttttctcc tacagttcca tccccgcgag tcgcacctct
     7681 cacgaaattt ccatcttcat aacgcaaaga aacggaaagt ccatctattt ttagttcaca
     7741 gcaatagtca actacacgtc ccactgcttt ttgtacacgt tgatcaaaag ctatcagctc
     7801 ttctttgctg aaaacgtcgt tcaaactgta aagcggaata tcatgagtga ctttttcaaa
     7861 accttctaat acttttccgc ctactcgttg agtgggagaa tcagacgtga tcaaatcagg
     7921 atattgttcc tcaattgcta ctaattctgc gtattcttta tcataaacat agtcttccac
     7981 tgttggttta tcttctacgt agtattcgcg agaccattgg ttcagtcttg tacgaagttc
     8041 ttctgctcgt ttagcagctt cgtcaatcgt catttcatgt tccatcattt accctccact
     8101 actaagcttt ttcaattggc gcaaaggcag ccaaaagacg ttttactcct tgacttggga
     8161 aagccacatc tagttctaga tccttcgacg tcccgcttac tcggacgact gttcctagac
     8221 cccatttttt gtgtttgact ttatctccag gtttccagct gttattttcc cctccagtag
     8281 cacttttaga gggaacaacc gctgtctctg gctgtttata gctatatgct gtttttttag
     8341 cgaatacagg tgttttttta ggcgtaggac gcatgccttc gatttccagt aactcctgat
     8401 cgatttcttc tacaaaacga gaaggtcggt tatattgcgt ccgtccatat aatgttctgg
     8461 agaaagcatt tgttaaatac aacgcttctt ctgctcgcgt gatccccaca tatgcgagac
     8521 ggcgttcttc ttccagttcg ctttcttcca tcaatgctcg agataaagga aaaaccccct
     8581 cttctagacc aatcaggaat acaactggga attctaatcc tttggctgca tgcaaagtca
     8641 tcaatgtcac ttgggaagca tcttcttcta aattgtcaat atcggaaaca agtgccagat
     8701 catttaagaa gaccgttagt ttttcttctg gtgcatcagc gtcttcttca ttttgctgtt
     8761 cgaattgttt gtcgaattct tgtgtgaccg ttaaaaattc ctccaagttt tcgatgcgtg
     8821 cttgtgcttc taatgtattt tggattttta agtcttctag atatccgcta cgatccaaaa
     8881 cctctttcgt caattctgtc actgtcaagt atgggatcat ctgagtgact tcttggatca
     8941 tctctccaaa tgcacctaat tgctgtcctg cttttccacc gatatttgcc agatccacat
     9001 tttgcgctgc ttcaagcagt ggccattcat gaagagaagc aaaactgcgt agtttttcga
     9061 tagatcctgg tccgatgcct cgtttgggcg aattaacgat acgctcaaaa ctgattgaat
     9121 cttgaggatt tgccagcaca ttcaaatacg ctaaaatatc tttgatttct ttacgatcgt
     9181 agaacttgtg ccctccaacc attttataag gaatatttgc tttcaacaga gtttcttcca
     9241 ttacacgaga ttgtgcgttc gtccggtaca agatggcaaa gtcgccgtaa ttccgatgat
     9301 tgcttcgaat ctcttcttgc atccgatcta cgataaaacg ggtttcgtct cgttcattat
     9361 ctgcacggta gtaagtgatc ttgtttcctt ctttgttttc tgtccacaag ttttttggtt
     9421 ttcgattgct attgttttca atgacttggt ttgctgcgct aaggatgttt ttcgtggagc
     9481 gatagttttg ttctagcaaa attactgcag catctggata atctttttca aaatccaaga
     9541 tgttctgcat atctgcaccg cgccagccgt aaatactttg atctgcatct cccacgacgc
     9601 acaggttcct aaatctacct gccaataaat tgactagcgt atactgtgcg tgatttgtat
     9661 cttggtactc atctacatga atataatgga atttgttttg ataatatgtg agtgaatcag
     9721 gatgttcttc aaataatcga atcgtattca tgatcaggtc gtcaaagtcc atacattgat
     9781 tatattgaag ctctttttgg taagcagcat aacattttgc cgcaatctct tcgtaataac
     9841 tgccttgcat ttttgcaaaa tcctgagggg tctgcaggct gttttttgct tgagagattg
     9901 ttcctaatat acttcgagga tcatattttt tcggatcaat gttcagttct tttagtatcc
     9961 gtttcatcaa ggtcagctgt tcagaagaat cgatgattgt aaagttccgg ttatacccga
    10021 taaaatcaac atctcttctt aaaatacgca cacacatcga gtgaaaagtc gatacccaga
    10081 catcttcgcc tccagatgcg agaatcgcat tgacacgttc tttcatttct tttgcagcct
    10141 tattggtaaa agtaatcgct aggatgttcc aaggattgac ttctttttcc tcaatcaaat
    10201 aggcaatgcg gtgtgtcagc actctcgtct ttccacttcc tgcacctgcc attagcagta
    10261 atggtccgtc agtgtgaaga acagcttctt tctgacgggg gttcatcccg tttaataatt
    10321 cagctttgga tgacattaac aacatccttt cttttatcaa tcttgttaat tatagcattt
    10381 tcttggcttt cattaaacta gctagttcaa aatcatttgt ttctttttat ggatttttcc
    10441 ttgtcaattc gttgatttcg cgctaaatta aaagaaagcg aggcgtttga atggaaaaaa
    10501 aaggaaaaat caagaaatta gataagactc agatatattt tattctaaaa ggaatatttg
    10561 ttggactgct gacaggaatc gtcgttagcc tgtttcgatt atctatcgaa aagctaagcg
    10621 atttagttcg aagtatctat gaaatgagtc gggaacagcc gatttactta attggcctag
    10681 ctatttgctg catccttgca gcatttttcg tgggttatct ggtcaaaaat gaaccggata
    10741 tcaagggaag cgggattcca caagtagagg gacagcttcg cggggaatta tcaatgaact
    10801 ggttctctgt tttatggaaa aagttcattg gcggtgtact ttcagttggt gcgggccttt
    10861 ttctaggtag agaaggacct tctatacagc ttggcgcatc cattggacaa ggagctggac
    10921 aattgtttcg gagtccatct tcagaagaaa agattttaat ttctagcggt gcaagtagcg
    10981 gacttgcagc agcattcaat gctcctatcg caggattact ctttgtttta gaagaaatcc
    11041 atcactcctt ttctccactt gtttggctga catcatttgc ttcagcaatc actgctaact
    11101 tcgtctctct ttactttttc ggcttgagac ctgttttata tctaggtgac cttccttctt
    11161 tgccgttgaa atattatggt tccttagtga tcttaggagt acttctaggc atcttaggtt
    11221 ttatttatca gaaggtcttg ctggctttgc caaaatttta caaccgattg cctttaccag
    11281 cttattttca cgggttcgtt cctttcttgc tgattttgcc aattggttat ttatggccta
    11341 gtactctagg cggaggcaat caaatcgttt tagcttttgg acatgcttcc ttgccaatca
    11401 ttatgattat cggtttgttt gttcttcgat tcgttttttc catgatttct tacggtggtg
    11461 gtcttccagg ggggattttc cttccgatat tgacattggg ggctttaatc ggtagctttt
    11521 atggaaacat tatggttgat ttcgggatgg atccaatcta catcaaggat tttgtcgtta
    11581 ttgccatggc tggttatttc acagcgattg gaaaagcacc gctgacagca attattttag
    11641 tgacagaaat ggttggctct cttaatcatc tgatgccttt aggattggct gctcttgttg
    11701 cttatatcgt caatgacctt ctcggcggta atccaattta cgaatcatta ttggaacgtc
    11761 tacttggaaa tactcagacc gcctcactaa aaggtgcaag gacaactttt gattttccag
    11821 taacggcaga gagttcttta gacggattaa tggtacgaga cttcaattgg cctaaaaata
    11881 tgctgctaat ctctatacgc agaggaaatc aggaaatctt gactcacggt gatacgatca
    11941 tgaatgtagg agatattttg gttatcttga ctgatgaagc aaacttgcca agaatcaagc
    12001 aggaaatcga ggctaaatct tctatcacaa atttgaagca atcattttaa cgaacatgga
    12061 aaaactattt tacaacaact attcatctac actacttgat tctatatgat tctataaaaa
    12121 aagaagagac tgggaaaaac cagcctcttc ttttttattt ctatgcttct gctgctgcag
    12181 gagcttttct caataaacca taaatcacac cagatacgac tgctccgata gcaataaaca
    12241 ccaaatacat gaccgggtga ctcagtaaga atacaacgaa aatcccgcca tgaggagcca
    12301 gtaatttgat cccgaaagct ccgactaatc cgccagttaa agcagaacca ataataaaac
    12361 ttggaatggc acgaatcggg tcagctgctg caaatggaat cgatccttcc gtgacaaacg
    12421 atagtcccat cacgatgttc gtcaaaccag catcttgatc tgttttgctg aatttattct
    12481 taaacaaacg tgtagcaacg aaaattgcca atggaggtac cattcctcca gccataacag
    12541 aagccatcac gacacttccg ccagttgcaa cagtcgtagc taaagttgct gtaccaaaca
    12601 cataagcggc tttgttgatt ggaccgccta aatctgccgc catcattcca gctaataatg
    12661 caccaagtaa agcagcattc gaaccactca tacttgtcaa gaaaccgttc aatgcatcat
    12721 tgattgcttt catagggaca ttgaccagca acatcaagaa accagtaatc agtaagccaa
    12781 acactggata aaagaggatc gttttaattc catccaatga ttttggtaag ttcttgaata
    12841 atttacgtaa aaatacgatg acataaccag ctaagaatcc accaatcagt gcacctaaga
    12901 atcctgcacc gcctgtatta gctaatgcac cagcagcaaa tccaacgatc aaaccagggc
    12961 ggtcaccgat acttgaagca ataaatcctg ctaataccgg cagcatgaaa ccaaatgcag
    13021 cttgtccgat ttggttgaac cagctagcag cttgattgta attccctaga tttgataatt
    13081 gatcatgtgg cacgccaata aattggtcga tcatgaaaga aagcgcaata gcgattcctc
    13141 caccaataac gaaaggtaac atgtgtgata cgccgttcat caaatctttg taaattcttt
    13201 gtccgatagt accatccgca tttccttctt ctgaactgct ttcttttcca tcaccatgga
    13261 atactggtgc agtaccacta agggctagat tgatcagctc ttctggttta cggataccat
    13321 cactgacagg acgattgatc agttcttttc cgtcaaagcg attcatctct acttttttgt
    13381 ctgctgcaac gattacacct tctgcacggg cgatgtcttc agcagtcaat cggtttttga
    13441 ttccttctga accgttcgtt tcgactttga tctccacacc catttctttc gcttttttct
    13501 tcagagcatc ttctgccatg taagtgtgag cgatccctgt tggacaagct gtaacggcaa
    13561 caacgaattt tctttctgga tgagcagaag cttctgcagc ttgtgtttct tgttctgctt
    13621 tttcttctgc ttctttttgc tcttcagctg tttggaacaa gtcttggact tcttctggtg
    13681 tatttgcttc ttttaatttt cctacgaaat ctgcatcaat cagcaatcga gatagtgctg
    13741 ctaatgcttg caaatgtgtg tcgtttgcgc cttctggagc tgcgatcatg aaaaacagat
    13801 aagttggctg tccgtctaag gcttcataat ctactccttt ttggcttttt gcgaataaaa
    13861 ctgttgcttc tttaactgca ctgtttttcg cgtgaggcat ggcgattcca tcaccaagac
    13921 ctgtagaagt ttgtgcttcg cgggctagaa ttccttcttt atatgtttcg atatcggaaa
    13981 tccggccggc atcaaacatt ttttggacca tttcatcgat tgcgcctttt ttatcagtcg
    14041 cttgcaaatc catgatcatc gcttctttga ccattaaatc cttgatattc atgattatcc
    14101 tccttgaaac taatcaattt ttgtgatttc aacttctggc agcaactcat caatcaattc
    14161 gcgagctgcc aagtcatcag aaaaagctgt tgcgcttccg caagcaactc cccatttaaa
    14221 ggcttcgatt ggatctttcg tacggctgta agccccaata aagccggcaa tcattgaatc
    14281 ccctgcacct actgaatttt tcaatgggcg aactaataca ttcgttttat aagttccttg
    14341 ttccgtgaag agcaaagcac cgtctccagc cattgagatc agcacattct gtgccccttc
    14401 agctagcaat tttttaccat acggaatgat ttcttctaca gattggaagg ttgtattgta
    14461 aagctcagct aattcgtgat tgtttggttt gatcaacaat ggtttcttaa caagtgcatt
    14521 ttttaggtca tcacctgttg tatcaatcac gaaatctgca cctttttctc gaatgatatc
    14581 aatcagttct tgataaaatc cttttcgcag gctagccggc gcgcttcctg acaatacgac
    14641 gatatctcct tgtcctactg ttcctaatgc ttgcttcaac tcatcgattt cttcatctga
    14701 aatagatggg cccaaaccgt taatttcagt ttcagtatct gattttagtt tgatattgat
    14761 tcttgtatct tcttttacgg ttgtgaacaa agactggatt tgttcttttt caagccactt
    14821 cgaaataaat tcgccagtga accctcctaa aaaccctagt gctgtagatt gagaatcgat
    14881 ccgtttcaaa atacgggaaa cattgatccc ttttcctcca ggtaacttga agtcttcctt
    14941 cattcggttc aaatcgccta gttttaaccc atctacgcgt acgatataat caattgatgg
    15001 attaagtgtt actgtgtaaa tcattgtatt gcctccttaa ttgttgtctt ttcacggaat
    15061 tcattaacga attctaatgg acaacgctcg gttatgatcg tggctgcttc caaaggtgca
    15121 acagaggtga aggacaactg gttgaatttg gtatgatcaa tcaatacaaa tgtctcttcg
    15181 gaatttttca tggctaaacg tttaacagct gcctcttctg ggtccggagt cgtgaatcct
    15241 tgttcaagat gggcaccgtt cattcccata aatgctttat taaaatgaaa attttttagt
    15301 tgttctatcg cattagatcc taaaacagca ttagttgcca gctttatcgt tccacctaaa
    15361 ataatggtag caagctccaa atcaactaaa tttgccgcat gttgaacgga atttgtcact
    15421 actgtgatct gttttccttg cagaaaagga atcatttcta acgtagtaga gccagcgtct
    15481 aaataaatga catcttcgtc attaatggtt tcagctgccg atttggcgat ttgctgtttt
    15541 tcgtgaacgt ttttgagtga tttttcactc atattctgct caaaattcaa taattgctct
    15601 ttcttagctc cgccatgaac tctttctaga aacccactat tctccagctc ttgtaaatca
    15661 cgtcttatcg ttgattcaga agcattaaaa aggtttacaa gatcttgtga tttcacgatt
    15721 ttctgctgtt caagcaagtc taggattttt tgtctacgtt cctctgtaag cattttcacg
    15781 atcacctcaa tacaaataat agcatatttt ttttctactc gcaatataaa tcagtcaaaa
    15841 acgttcataa aaattataaa tcagtcaaaa aaaaataaaa aaccagtcaa aaagactggt
    15901 tttttatttt tttgtctatc atcaagccgt tttatcgttt tttattttcg cttcttgttt
    15961 ttttcatata aacagaagca ggttttcttt ccttatgaag aagataataa taaagtccca
    16021 tcccgccaaa catgaccaaa aaaccgatga ctgatcgaat aggaaaatta ggaacaaaaa
    16081 agagacagac ggataataat gatgccggaa ccattattcg ataatagagt tgtttatcca
    16141 ttttcttcac ctcatatttt ttgtaaagta atcaattgtt ctaattctcg gtaatctaaa
    16201 aattgcacac gcagatgctg ctcacctttc ttgacatcga attggatact tcgccgcttt
    16261 ttctttattc gtttgaaggt aacatcagag agtctatgtt tgatttcctt taacggtaat
    16321 tctgacaggg attctgaagg aacatagatt cttaaggata aaagatactc ttgatatttt
    16381 tcatctgtta cctctacttc tagatattcc ctaatataat aacaataagc ttcgattcca
    16441 ttatccaaag caacagtcgg atcgataact ttatagcaca tcatgcgcga gcgattctcg
    16501 tcaacccaag gaaaatacgc ctgagcattt agtgttccgc gaacacgcct ttctttataa
    16561 tctccttgtt gaatatcata actttttgtt acaaaaaatg aagcattctt tttaggaaca
    16621 ggttgcattt gtgcattctg atactggaca gattggatcg tatggtcagt gtaaatgtat
    16681 tcaacgaatg gcggtttcaa taaaccgaca ccattgtccc aagcaagatg atcaaaccca
    16741 agctggtccc taaaatagga ttgaaacatt tgattgtttg gcttttgcca gttaaagggg
    16801 tctcgataaa gctggataca tatgacttcg ttttctaatt ccttcacttt ttctacttgt
    16861 tggatgtcga gaaaaatcgg tttagggatg atttgatgat aatagcgact ataatacatt
    16921 tcccaacacg aagtgaaaca taaaccttgg taaaaaagat cgtatcctgg aaattggttg
    16981 caatcgacta ctacttcccc gttttgttgt ttcattttag gtaaatgttc gatttcatcc
    17041 tttttctcaa acaatagccg ttgagagatc tgttttgtat tgtgatagat aaactcgcta
    17101 taagctcgca tataggcgaa caccccatga gcaatcattt ttttctgaat gaagtctcga
    17161 atcaaaaatt gcttttcttt gaaaacagag atagacaata cattttttat caataattga
    17221 ttatcttcca agcgaaaact acattcgttc tcgtcatttc ctacaactaa ccaactttcg
    17281 tctcttaccg atgctagcat tattttttct tgaagctttc gaagatcata cggatccgct
    17341 tgttgtgtga aagagcggat aaatgttggc tggatcaaca gacgtgtcaa aatagcccaa
    17401 tcgcttattt cctgtttttt ttcttcttca tttaagtctg tgagctggat agtcatcaat
    17461 aatttatctt cgccaatcat tttctcacct ctttaaaatc tttttataat ttaattataa
    17521 ccaacgataa agaaaaacta aaactttatg tcttagaaac caatttggac gattacatga
    17581 tagactaagt aaaaagaaac aaagaggtgt ttacaatggg gttgaaattt gaacgtacag
    17641 ataatttaga taaacttttc gaatcatttg ctgtcgatcc ggaaaaaaca gttgcaccaa
    17701 aagaagagat cgatcgattt ctaaaaccac agccacaaaa tgaaaagaaa aaagacaaga
    17761 aacaaaagta agttaagctc aaaaaaagac ttaccagcca aacttttatg aaagagtttg
    17821 actggtaagt cttttttatt ctttttatga ttcaattgct tgttcgattg ctgcccacgc
    17881 ttcttctttt ccctgttttg taacggaaga aaagagaata aacgtgtcat tgcgatcaaa
    17941 atccaacgct tttttgattt cgctctcatg cttgttccat ttaccacgag ggatcttatc
    18001 tgccttagtg gcaacaacaa ttacagggat atcataatac ttcaaaaatt gatacatctg
    18061 gatatcttct tgagaaggct tatgacgcaa atctactaaa gaaacgaccg cacgtagctg
    18121 gtctctagtc gttaaatatg tctcgatcat ctttccccat tttgctcgct cagttttgga
    18181 tacttttgca tacccatatc ccggaacatc gacaaaatgt aatgcgttct cgatcaaata
    18241 aaaattcaat gtctgggtct ttcctggctt accggaagta cgggctaaat tctttcgatc
    18301 aatcaatgtg ttgataaaag aagatttccc tacatttgat cgtcctgcca gagctatttc
    18361 tggcaattgt gtatctggat attgttttgg tgccactgca cttatgataa tttcagcttg
    18421 atggactttc atggtctctc tccttaacaa ggtgatgaat aaagcaagcg gctgtcgcaa
    18481 aagccaaaat gacttttacg gcagcctctt ttcatcaacc cgcttttttc tctgaatctt
    18541 tatagattac tgttggctca ccagacaatt cagctgcttc ttttgtgata atcacttttt
    18601 cgatgttttc atttgaaggg atatcaaaca tcacatccat catgatttct tcaatgatgg
    18661 aacgaagtcc tcgagcaccg gtattgcgtt cgattgcttt tttcgcaatg gctctcaacg
    18721 cttcaggttc gaattcaagt tcggtattat ctagagaaag aagtttttga tattgtttga
    18781 ctagcgcatt tttcggctca gtcaagatcc gtaccagatc atctgttgtc aatttctcta
    18841 aagctgccat aacaggtaat cgtccgataa actcagggat caatccgaat tttagtaaat
    18901 cttcaggaat gatatgctgc atgacacttt cgtcttcaga aagtttttgg ttttgtgtac
    18961 caaatccaat cgtcttttcg cccatacgat tcttcacaat cgtttcgatg ccatcaaatg
    19021 caccacctac gatgaacaat atgttcgtcg tatcaatctg aataaattct tgatgtggat
    19081 gtttacgtcc tccctgaggt ggcacgcttg caacagttcc ttctagaatt ttcagcaagg
    19141 cttgttggac accttcgccg gaaacgtcac gagtaataga tacattttcg cttttacgcg
    19201 caattttatc gatctcatca atatagatga tccctttttc tgcacgttcc acattgtaat
    19261 cagcagattg aagcaattta agcaaaatgt tttctacatc ttcccccaca taaccagctt
    19321 ctgtcaaact tgtcgcatct gcgattgcaa aaggtacatt caatgttttt gctaatgttt
    19381 gtgctaaaaa tgttttacca gaccctgtag gtccgatcaa gcagatattg cttttttgca
    19441 gttcaacatc atctgtgttt tcttgtgctt gctgattgac acgtttatag tgattgtata
    19501 cggcaacagc taacgagcgt tttgcgcgat cttgtccaat cacgtagtta ttcaatactt
    19561 caagaatttc tagtggttta gggacttcag tgaattcgcg tacagcttct tcataaaatt
    19621 cttcatcaat gatttcttta cataggtcga tacattcatt acagatgtag acccctggac
    19681 cagctacgat ctttttcact tcttcttggg ttttcccgca aaaagaacag cgtacggtct
    19741 cattgctact tggattgtca tacatggtct tcacccctta acttgcaaaa agtatgcaag
    19801 aaactatcaa agactttaca gtcttttact atcataacat agtttagtaa aaagaaaaag
    19861 tgtttaacaa aggatcaact gacctatacc tttgcatttt ttactcttaa caaaaaataa
    19921 ggaactgtga caaaatcgtg tcacagtccc ttatttcgaa taaacaattt tctagaagta
    19981 gcttcttcag aaatgattta ttacttgatt tctattcttt cgcttctgtc gctgtacctg
    20041 tgatcaattc gattgctttt ttcattgtca catcatgttc cagcatatct tctgtcaaca
    20101 cgcgtttgat ttgttcgatt ggcatgttgt atgtttctga taattcttgg atttctgcat
    20161 tgatttcttc ttctgttgct tgaagatttt cagcagctgc aattgcttcg atcacaagat
    20221 ttgttcttgt gcgcatttct gcttcacctt cgaattgttt atgcaagtct tcttctgtag
    20281 aaccagttaa ttgatagtac atttcaggag agataccttg acgttgcatg ttgttcaaga
    20341 attcgtccat tgaacgatgt acttcatcat gaaccatcac gtgtggcaat tcaacgattt
    20401 ctgcgttttc aacagccata cggatcgctg cttcatcttt tgcatcgtcc gctgcttttt
    20461 cttttgtttc tactaattct ttgcgatatt tttctttcaa ttcgtctaat gttgatactt
    20521 cgtcatcaac atcttttgcg aattcgtcat ctaattcagg cacttctttt gcttttactt
    20581 catggattgt cactttgaag actgcttctt ttccagcaag atcttctgct tgataatctt
    20641 ctgggaaagt tacatttaca tctagacttt cacctgattt atgaccaact aattgatctt
    20701 caaaacctgg aatgaatgag cctgaaccta attcaagtga gtaattttcg ccttttccgc
    20761 catcaaacgc ttcgccatct acaaagcctt cgaagtcgat tactactgta tcgccatttt
    20821 cagctgcagc atcttctttg ataactaatt cagcttgtgc ttcttgttca cgtttgatac
    20881 gtgcatccac gtcagcatct gttacttcac ggtcttgttt ttcaacaact agatctttat
    20941 attgtcctaa ttttacttct ggtttcactg ttacttcagc agtgattacc cagtcttgac
    21001 ctttttccat gctttcaaca tcgatttttg gttgagaaac aggatcgatg ccagcttctt
    21061 tgacagcagc ttcataagct tctggtaata cagcattcaa tgcatcttca tataaagctt
    21121 cttcaccgta catacggttg aatacttgac gagaaacttt ccctttacgg aatccaggta
    21181 cgttcaagct ttttttcact ttattaaacg cagttgttaa tcctttttgg atttcgtctt
    21241 gcgcaatcgt aaattttaaa acaccatcat tcgtgccttt tttttcaaat gttgcagtca
    21301 tttaattccc tccgagttta gaaattcatt ttatacatca aaaacgtttc atgcatacct
    21361 ttaaatagta cactaaccct ttcaaattgt aaacatattg aatggataga atccttgttt
    21421 ttcataacat ttttatcttt ttcactgata aaatctaatg gaagaagatc atttgctgca
    21481 aaattttttc tctttttttt aaaaaatctt gtttttcatc ttctgtacct tcatacatcg
    21541 tttttcctgt acacgcctct acagtcagtt gaaaccagcg cttcgggtct tcgatgtatg
    21601 tatcatagac aggataaaca attgcagatt gcaacgtgaa ttcttcattt aacacggaac
    21661 taagcagcgc atcttcatta ccgtaacgat ctgaaaatac acataattgc tggtaacttg
    21721 cctgctgctg cggctttggc agatcttttg gtatgacttt gactaacttt tcttcaatcg
    21781 tcaaatagaa aacaggatgg cattcgttca attgcctaag tgtctccagt aattttgccc
    21841 ttgctaaaat atggacctct ggcgatacaa taagtttact cgctgtttgg ataaactcat
    21901 gataaggaag ctgttcgatc tcatcaatag acgcaagctg acgtgcaggt tccaacgaag
    21961 gaagttcctc cgatttattg tggagtgcct tgatcttctg cctctccatt tgtccggata
    22021 attcttctgc aaattggatt ttttcaatga cccgctgctc gaaagcttca taaaaatctg
    22081 tacttgctat caattttcta gcatataaaa aatcttgtgt actgattaac aagtcaaaat
    22141 aaaattcagc aaactcctca ttttgaagat actgtttttc atgcaagagt gcttgcttca
    22201 atgcttcttt tttctcgtcc aactcgtaaa gacaaaaaac aagcaggcta ttagcctcaa
    22261 agctttcttt caactcgtaa gctcgttgaa ataattcttt tgcctgctga tattgctggt
    22321 ttgctagtgc ttgttgtgct actcgcatta aattctcata tttttctgga aaatcaatcg
    22381 gcttcacgca gtgtcctcct cttgctcatg ttcagctcat gttcaatagt agcaaaacaa
    22441 aaaaagcatg acaattaaaa ataactgaag caccctctaa aagctagatt ttagatctga
    22501 cttttagaag gtgctttcaa ctgttactgc tttttattgc tcatcagctg ttgacttcct
    22561 ggttgaatgc tttgatcaga ttgatcgtaa caacacttgt attagtgaaa aaatcgccta
    22621 gatgttgctt tttctgatta aagattgctg gaagataccc taacatcagc aaaggaaatt
    22681 ttagaatgaa ccggcaagca ccttctctaa ctaaaacggt tgaccagcta agttcttctt
    22741 catcaaagct gatgactcga ataccaaaga tcattttccc aatcgtttga ccatgattga
    22801 atttcgtcaa taaaataaaa tacgctagat aaataagtaa ggctgtgaat ccgtagatac
    22861 tcagataaga atctgaaaaa ttaagccaac ctagattttt ggcaatacca agtgttaaac
    22921 gcgtaatagc tccgatacac aaaagatcga ccaagaaagc aaacattcgg ataaaaaaac
    22981 ctgcatagaa atacttagga aaatcatttg cttttggcgg ttcatttctt gtgtccgtat
    23041 actttttcca tttacgttgt ttctttttga tttcttcggg cgtcaaaggc tctctttcaa
    23101 aagagctcag taccttttgg gaaaagttgg agtcaggtcc tacagcaggc tgctgttgct
    23161 tatctttttc ttgttcctta ttttcatttg aaagctctga catgcttact cacctccgta
    23221 ataatacatt gcttttggtg attccgctgt ccctagattc tcaagaacgg ataagatctg
    23281 actagtctca gaaggcttca atccctggaa ttctgctagt ttacttccta accatgtact
    23341 agcaaaccca gatggcgtgg aagaatattc tactagttcc gcatcttcaa gctgttgttc
    23401 ctttcgcata gcttttaaag catcttcagg aaatcccaat tcatcgacta aacctacttc
    23461 ttttgcttgg acaccatcat aaatccttcc atcagcaatt tttttgactt cttcttcaga
    23521 tttattccgt ccctcgctga cgattgctac aaaacgacta tatgcgctgt cgatatatgc
    23581 ttgaagcacc gcttcttctt cttttgtctc tggtcgcgtt cctgaaccca tatctttcaa
    23641 cgctccgctt ttaactgttg tatcttccac acccagtttt tctagaagtc ctgaataatt
    23701 caatcctgac atgatcacac caattgagcc ggtcactgtt tcttctgttg caaagatttt
    23761 atctgcttga gcagaaatat agtagccacc gctagctgcc atgtttttca tgctgacata
    23821 cattgggata tcatgttctt tacgaatcgt atccaatttc ttagcgattt ccgcactttc
    23881 gtagacaccg ccaccaggag aatttacttc taaaaagata cctttgactg ttggatcttc
    23941 ttcaatcgcc ttcagttgtt ccataaaatt tttatgattg taaccttcag aagcaaataa
    24001 acctgaagac cctcccgcag caatcgttcc atctactgat aattttacga ttttttgcgt
    24061 actgtctccc tcttccaaca catttgaagc tagttcttca tccccatata accaactgtt
    24121 caatccctca atttgatcgt tttcctgagg cttagtcaaa ctagctgaaa ctaacgaaac
    24181 cacaaataat cctgcagcaa tcagaactgc tgcccaacgt ctcttattca ttctttctcc
    24241 tttctaatac aagtttttta tgacgatcac agtttctgac tgctcagaag tgtcgaaccg
    24301 ctctgctttt tcttcccgcg catacccgga aaacgactct tttgtcaatt catcttctac
    24361 cgtaaactca cgagcttcag caacttccaa ggcatcaggt gcgatttctt ggatgctatc
    24421 ccagccagta tctaaaaata ttttcgtatc atctgataca ccagctgatg cttcgaattt
    24481 ggacaattgt ttttttaaca ttcccagtgt catgatctca atttttgaat ccatttttac
    24541 tcctcctcta tccgattact ttctattgta ccgaactcct gaaaaagatg atagataaaa
    24601 acccattatt ttttgacata aaaagagcat ttgacaaagc atttgatata taccaattta
    24661 ttttttattc tttttttgtt gacaagaaca ttcgcaaaag gttatgattt taaatgtttc
    24721 cagataaaaa acaaaagagg aggatagtta taccttttag gatagcgcca ggtctgtgta
    24781 aacagatgac gaggagaggg tttatcgaaa gattcggcgg atggccctag ggactgcact
    24841 ctacagaaaa tccacaaaaa atatctgcaa agataaaaca aaaggatttt cctgcagctg
    24901 gaagcattca tacgaattca ttatagaaag taggatgttt tttatgtgcg gaattgttgg
    24961 aatgattgga ttaaaaaatg taacaccagg attgattgac ggtctagaaa aattagaata
    25021 ccgtggttat gattcagctg gtatctttgt ctcagatggc acaactgatt atctggtcaa
    25081 agcacaaggc agaattcaaa atttgaaaaa caaaataaat attgatacta caggaaatat
    25141 aggtattggt catacacgct gggcaactca cgggcaacct tctgaagaaa acgcccatcc
    25201 acatacttcc caaagtggac gcttcgtgct cgttcacaat ggcgtaatcg aaaactttga
    25261 agaacttaaa attgcttatt tagcaaatga ccactttatt ggtgagaccg atactgagat
    25321 tatcgctcat ctaattgaaa ctttcgcgaa ggatactaca acgcaagagg cgtttttaaa
    25381 agctttgcgg gtcatcaaag gttcttacgc tttcgctttg attgatcgga cagcacctga
    25441 tgttatttac gtcgctaaaa ataaaagtcc actattaatc ggactcggcg atggattcaa
    25501 tgtgattgcc agcgatgcaa tggctatgct tgctcatacg aaggaattcg ttgagattga
    25561 agatgaagag atggttaccg tcacatcaga aaaagttatt attcaaaatt ttgcaggtga
    25621 catcgtagaa cgttcttcat tcgaagcaca agtagattct tcagatatcg agaaaggtac
    25681 ctatcctttt tatatgctga aagaaatcga cgaacagcct attatcatgc gtcgtatcgc
    25741 tcaaaaatac gtaacagaag acaatcgtgt ctctcttgat caaaagctgg tcgatacatt
    25801 gtctgatagc gatcgaatct atatcgttgc ttgcggaact agttaccatg cggggttagc
    25861 aggtaaacag actctggaaa aattgacaca gatccctgtt gaggttcatt tagccagtga
    25921 atttggctat aacacacctc ttctttcaaa aaaaccattc tttattttct tgagtcaaag
    25981 tggcgaaaca gcagatagcc gccaagttct ggtaaaaatc aaccgtctcg gctacccttc
    26041 acttacgatt acaaatgttg ctggttctac tctttcgcgg gaagcatcct ttacactgct
    26101 attgcatgct ggacccgaaa tcgcagtagc atcaacgaaa gcttatactg cacaaatagc
    26161 tgtactaact ttattagcca aagctatcgg tgataaaaaa gaatttgaaa cttctcttgt
    26221 attcgatatc actcatgaat tgagtttagt tgctaatgcg atggaatcgg tcatcgccca
    26281 aaaagattat ttagaagagt tggcagaagt atatctcagc gatacaagaa atgcctttta
    26341 cattggacgt ggcgctgact acaacgtttc tcttgaagct gctttgaaat tgaaagaaat
    26401 cagttatatc caggcagaag gttttgccgc tggcgaattg aaacatggaa cgattgcttt
    26461 gatcgaagaa ggaacaccag tgattggaat catcagtgaa gaagtgactg gtgcgcatac
    26521 tcgaggaaac ctgaaagaag tcgaaagccg tggcgctaaa acactagtta ttgtctcaga
    26581 gggattagaa aaggaaagtg accagctggt gctaccaact gtccaccctt atctaactac
    26641 tctaaccaca gtcgtaccga ctcaattact tgcatattac gcaacgctat tacggggatt
    26701 cgacgttgac aaaccacgta atttagcgaa atcagtgaca gtagaataat aaaagaacaa
    26761 ggaccagtgt cagacatctg acactggtcc ttgttctttt attttttatg aaaatatctc
    26821 ttaatccagt ccgatttctt ctttgactac tgccgcgatt ttatcgacat agtaattaac
    26881 tttctcatca gtaggcgctt ctgccatcac tcgaagtaat ggttctgtac cggaaggacg
    26941 aactaggatt cttccttctg atcccatttc agcttctgcc tcttcaatca cttttttgat
    27001 tgccggaaca tccatcgcac cgtttttatc acttactcgg atattcacta atttttgcgg
    27061 atagattgtt acctctgctg caagctctga taatttctta cctgtctgtt tcatgatatt
    27121 cagtaactga attcctgaaa gcatcccatc tccagttgtg ttaaaatcta agaaaatcat
    27181 gtgcccagac tgctcgccgc caaagttata atcgtttttg cgcatttctt ctacaacgta
    27241 acgatcacca acttgtgtaa cgacatcttt caaaccgatt ccttccaccg ctttgtggaa
    27301 tcctaagtta ctcatgacag tcgtaacgat cgtatctttt ttcaatcgat ttttttctgc
    27361 caagtattta gcacagataa acatgatttt atcaccgtcg acaatgtttc caagttcatc
    27421 caccgcaata atacgatcgc catcgccatc gaaagctagt ccagcatctg ctcctttttc
    27481 aacgaccatc tcagctaaac gttctggatg ggtagagcct acgccatcat tgatatttaa
    27541 cccgtctgga tttgtgccca tggtataaaa atctgtttca agatcggcaa acaaacgatt
    27601 aacacttgtt gaagttgctc cgtttgctgc atcgacacaa atggtcaaac cggaaaggtc
    27661 accgttgatc gtttgtacaa ggaattgaga atatttcaat aagccttctg gaaattcttc
    27721 tacagttccc aatccttcag ctgatggacg aggcaattca tccacttcag catctaataa
    27781 tgcttcaatt tctagctctt ggtcatctac tagtttaaaa ccatctgcac cgaaaaattt
    27841 gattccatta tcttgtgctg gattatgaga agcagaaatc atgacccctg cgcttgcttt
    27901 ttgcaaacgt gtcagataag caacacctgg tgtagagatc acacctagct ggaacacttc
    27961 gatacccacc gataaaagtc ctgaaatcag cgcttcttct aacatttgac ctgagattct
    28021 tgtatcccgc cctactaaca cgcgtgggcg ttttccttct tcttcatgct ggcttaggac
    28081 ataacctccg caccgtccca gcttaaatgc aagttctggc gtaagttcct tgttggcttc
    28141 accgcgtacg ccgtctgttc caaaatattt acccatagtt gtaaaattac tcctttaact
    28201 taattttctg aggaatttgt tctgctcatt tgtgttgatt cgcttgtttc tgatgtttct
    28261 tctgtacttg tggtcgagct gcttgtccca gattccgaac tggaagaaat ggttgttgtc
    28321 gatggttccg ttcctgaatc agcagatgaa atacttctac tcgtacttgt attttcttgt
    28381 gtccgactgc tcgtcgaagc agagctactg cttgacgttt gcaacacggg tgtaatctcc
    28441 acactaactg attcgggctt gatacttaac ccctcttcta ctggtatttc aattttacga
    28501 gttgttcgat gattgatacc tgagacattg atcggtacag caatactgtc accgatcgat
    28561 gcaagcaaat cgctagagcc gcttacttct gcttccagtt ttgaaaaact gaaatcatag
    28621 ctttctaccc cggcagctgg tgttccttgc tgtatcccat aaagtcgtac cgacttgctt
    28681 ggcttgatcg aatcagctct cactgttact tgcactggat cagagacgat acttaatact
    28741 tcccctgctg cattcagcgc ctgtattggg acctcactat taatcccatc atctgtgacc
    28801 atcgaagcgt ccacatcagc tactactcgt ttgatttctg ccaatgtttt gtcacctgta
    28861 gtgatagaga cttttttagg actaacggaa gtatcatcaa gttcatatcc agatggtgtg
    28921 aacgttgaag gaatcaacgt ttccacatcg aaatctttta ttaccttttt ctcaaccgtt
    28981 actgtaatag tcgatggttc gatctttgct gtgacagcac tgctcaaatt ttgaattttt
    29041 agcggaacct catgtgttcc ttcgcccagc ttagtgatat ctgctgtgac gcggaacatc
    29101 cgtgtatctt cgtttgcctc tgcattcaac tgaactcggt ttgcactgga aagtttgaca
    29161 gtcactgcat tttcatatcc atggatatag tagcgctttg aatcataaga aatcttgatt
    29221 ggcaccccag taactgtttg attatacgct tcatttccag aaagcgtatt tggaacggac
    29281 tggccatttg cattgaagta cagcgcaata ctgaacagca atgcaataaa actgtaaaga
    29341 atgcttgtcc gtttctcttt tgagatcatt tgcgatcccc tcccttagtc ataccgtcta
    29401 ggaaagattg aatcacgttt ttcttgtttt ttgttttctc ttcagcaatc agttctctac
    29461 gcaaaattgc caaatattct tgctgggata agccagccat cagttcatta tctaatgtaa
    29521 tgctgacatc cccagtttct tcagagacaa cgatggtaat cgcgtcgctg acttcgctta
    29581 taccgacagc tgcccggtgt cgagtcccga attcttttgg aatcaacata ctttctgata
    29641 gaggaagata ggcgcttgct actgcgatct ttccttcttt tacaataact gcaccgtcat
    29701 gcagcggtgt attaggaata aagatattga tcagcagctc tccagtgata tctgcatcta
    29761 atgcaattcc tgtctcaata tactcatcta atccagtatg ccgttcgata gtaattagcg
    29821 caccgatttt tcgcttggac atatattgga tggctttgtc aaaagacaag atcatcttct
    29881 catcttcctg ctgttcgctt tttgattgtt tgaaaagcga actgcgtcca agatgttcca
    29941 gtcctctccg gatttccggc tgaaaaatca cgatagcagc tatcaccccg tacgtaatga
    30001 cttggttcat cagccaagac aaggtgtgca gaccaatgat ttccgctacg attcggataa
    30061 caataaaaat agctacacct ttcagaagct gaatcgcttt tgtgcctcgc agcagttgga
    30121 tcagtttgta tacaagatac cagacaacca gaatatcaag tatgttcacc aaaaaattca
    30181 gagagaacaa gtcaccggaa aacatttgct gccaatagtc caaattaaaa agttccccga
    30241 tttgaaatga cataaaaagc ctctcttctc ttttgagatt tcctctctag tatatcatat
    30301 gttttaattt tagaggctga tctgctcgta tttttcttga gaaaaacgca taattttcag
    30361 gaaaattgca agtatgcgtt ttatttttct ctgcaataaa tatttttaaa cttcagagaa
    30421 ttattcatta tattttttct gttatttttc ctttttttct tttgtagctt gttccatttt
    30481 tttacgtcgt tctgctctgg cagctcttct ttcttctgct tcaaggtccg tcgttttttc
    30541 ttttctagtc ttaacgggta catcgataga ttcctctggt tcaagtcgtt tcttgatttt
    30601 ttctaattct cccgtcagtg cagcatagtt gtaaaaacgt gttttagcgt cttggatagt
    30661 cttttcaaat aaagcttttg caagatttgg atttgcgttc tctagcgagg aaaagcgaac
    30721 ttgtttcctc atgaaatcag gcatagcaga gaaatcaggt tttttgtagt ccaaagtcat
    30781 tgggttcttg tttttttcga ccattgcagg gttatatcga tataatgacc aatagccaga
    30841 agaaacagct tcttttgctt ctttaagcga ttctttcatt ccaccaagca aaccatgtgt
    30901 gatacaaggc gtataggcaa tgattaaaga aggtccagga tacttttctg cttcttcaaa
    30961 agcctttatc gtctgcattt gattggcacc tgaagcaatt tgcgccacat aaacatttcc
    31021 atatgtcatc gccatcattc ctagatcttt ctttgaagca tactttccac tagccgaaaa
    31081 tttagcgatt gccgaagctg gtgttgcttt tgaggtttga ccgccagtat tggaatagac
    31141 ttcgttatcc aaaacaagaa tattcacgtc tgctccgctg gcaagtacat gatcgatccc
    31201 gccaaaacca atgtcgtaag cccatccgtc tccaccaatc atccattggc tgttttttac
    31261 gaatagatcc tttctcttgt atatatcctc cagttcaggg acaattgatc gttcgctttc
    31321 gatcgcagct tgcagttttg ctgctctttg ctgcgttcct tcgctctcaa acatgtgtac
    31381 caaccagtct tccatcaatt ctcgtagttc ttctgatact tttggcaata cttctttgat
    31441 tgaacttgcc aaagcctcgc gacgagtctg tgccgctaga agcataccat aaccaaattc
    31501 agcattatct tccaataaag aatttgacca tgcaggccct tgaccacatt cattggtcgt
    31561 ataaggagaa gcaggagaag caccgcccca aatagaagaa cagcctgtcg cattcgcgat
    31621 catcattcga tcaccgaaca tttgtgtcaa taattttaca taaggtgttt cgccacagcc
    31681 tgagcaagcg cccgagaatt caagaagcgg ttgattgaat tgtgtagaca agacagtatt
    31741 ctttcctttg actggatttg ctttttgtct taatgtcatt gcaaaagccc aattcacagc
    31801 ttgttctttc tgttcttcat aaggcttcat cactaaagct ttttcttttg cgggacaagc
    31861 ctctacacac agaccacaac ctgtacagtc ttccactgaa acttggatac ggtattttac
    31921 gccgtctgcg cctcgcattt ctctcacgat aaatccttct ggcgcttctt ccatttcctc
    31981 ttcatctgct aaaaatggac ggatggcagc atgaggacaa acaaaggcac attcattaca
    32041 catcgtacag cgatcactaa tccactcagg tacttctaaa gcgacgcccc gcttttccat
    32101 agaagccgtt cctaaaggca tttcgccagt tgtcattcca tttgctacaa gtgtaccaac
    32161 agagagttga tttccttcct gtgcattcac tggttcaagt atttcttgta tataaccagt
    32221 gttcctttta ttgatttttt caggcatctc caacgttctc caatggtctg ggatcgcgac
    32281 ttgatgaagc agttcggtcg tccgatcgat tgcttgtatg tttttttcta cgatagccat
    32341 tgatttatgt ccatagcttt tcagggcttc ttcttttagc agcggaagca cctcatcaaa
    32401 aggaatgatg tcagctaatt taaaaaaagc cgtttccatt gccgtattga tccggcgtcc
    32461 caaaccgact tcttgggcca atctcatggc attgatcgta tagaatctaa tgttattttc
    32521 agccaagtaa cgttttaatt ttaagggcag atgcgtttct aattgttcgt cgctccaaag
    32581 agtattcaat aaaaaaatgc cacctggctt caatcctttg accaagtcat agctatgcag
    32641 gtaagctggt gtgtgacagg caacaaggtc cgcatgctcg acaagatacg ctgaacgtat
    32701 cggcgtatct ccaaaacgaa gatgagagac agtcagaccg ccagattttt tcgaatcata
    32761 ataaaaatag ccttgcgcat atttatcggt gtgatctcca ataatcttga tagctgattt
    32821 atttgctcca actgttccgt cagatccaaa tccccaaaac ttggcctgga atgtttgcgg
    32881 ttctgtcaaa tccagacttt cctttggttc caaagattga taagtcacat catccacgat
    32941 ccctatggta aaccgttttt tgcgtatgct tgggtctttt ttcaattcat caaaaactgc
    33001 tgagatttgg tcgggagtca catctttaga ccccaatccg tagcgaccac caataacagc
    33061 cgggcgaagt tcagaatcat ataacgcact ttgaacgtct aataagagag gttctccacc
    33121 tgcccctggt tctttacttc gatcaagaac agcaattgtt tttactgtat gaggcaactt
    33181 ttgcacgaat gtttccactg gaaaaggacg ataaagatgg atattcaaaa aacctgtttt
    33241 ccgtccgttt gcattcaagt aatcaatcgt ttgttcaatc gtctgtgcaa ctgatcccat
    33301 agaaacaatg acttcttccg catcgtctgc tccgtaataa gtcaccaagt cataagaagt
    33361 tcctcgtaat cggttgatct ctttcatata tttttgaacg atttcaggta atttatcata
    33421 ataggggttg atcgtttccc gttgttgaaa atggatgtct ggattctggt tcgtaccact
    33481 aacagtcgga tgattgggat tcatccctcg tttacgaaat gaagctaatt tctcctgatt
    33541 gatcagagga gctaattctt catattccaa aacttcgatt ttttgaatct cgtgactcgt
    33601 acggaatcca tcaaagaaat tcaaaaaagg tacttctcct tcaatagaag caagatgggc
    33661 aacaggtgct aaatccatca cttcttgtac actgctttca gctaacatag caaatcctgt
    33721 ttgtcttgca gccatcacgt ctccgtgatc tccgaaaata ttcaacgcat ttgtcgtcac
    33781 tgcccgacta gcaacatgga aaacacttgg cagtagttcc ccagcaatct tgtacatatt
    33841 cggtatcatc aaaagcagcc cttgagaagc ggtatatgta gttgtcagtg caccagtttt
    33901 caatgatcca tggaccacac cagctgctcc tgcttcggat tgcatttcta ctacttttac
    33961 tggttgaccg aatacatttt cttttcctgc tgctgaccat tgatctacta attcagccat
    34021 ggtcgaactg ggtgttattg gatatattgc agcaatctcg gtaaatgcat aagaaatata
    34081 tgcggctgcc gtattgccat ccattgtttt catttttcgc atgattcatc atccttgttc
    34141 atattctctc ttattatctg ttccattata acgtaaaaca ttccattttt tcttttattt
    34201 ataaaaatat ttcacatatg tctatttgaa ttggtcatct aatttttaga caaacagtct
    34261 aaatcgttgc ctttttttgt cagacatgta taaactataa gcgaaagagg tgttttaaca
    34321 tggatatatc agtgattgat gcaacgaaaa caaatacaca aaaaggaatc ctttatggtt
    34381 catcgaatgc tcctaaaaaa atggtcgaat tcatcaacct atcttgtccg tattgccgac
    34441 aatggtttga agaatcttat gagctattag aagaagcagt ccaaagcggg caattgcagc
    34501 gagtgatcaa attgttcgat aaagaaaaag aaagcttgca gcgaggaaac gtgatgcacc
    34561 ggtatctcac aatcagcgat ggtcaaaaag cgatcaaaga gatcaaacaa atattcgata
    34621 ctcaagacga gtggaaacat ctttctctcc aagaagtagc ggattttgca gtagataaac
    34681 taaagctgac agaacaaaaa gacgaacagc tgagccaagc tgtcatcaac gaagctgagc
    34741 aagcacatat tcgatttgtt ccgactgtca tcttgggtaa agaaatcttt gatgaatcta
    34801 tttcaataga ggaattaaaa gaattgatcc aaacaaaata aaaaaataag gagcgtagga
    34861 caaaagtaaa gaacactttt gtctcacgct ctaaacacct ataaacggcg gaagcagaag
    34921 caactccttc ttatttcttg gagttaaacg cttctgtccc agcctcctta ttccgaataa
    34981 atggtgtcca aaagcttgca tctgccagat tatctcattt cttatgacaa gctgagcaaa
    35041 ttatctccac caaataattt attcatattt ttgacttgcg catactaact aattcttaaa
    35101 ttttcataca aaatttctca aattccctta acgagtaata tttatgtacg gtgattcaca
    35161 ctagtatccc aatcactttt taagttatcc cgatttcaat tctacttcaa aaatagttgc
    35221 ttttatgtat gctgttagtt gattagatgg tcgtttgttg agctaggtcg tttattttaa
    35281 acaagttgtt tctttagctt atacctatct cgtctaccaa acgcaagatg gcaaacacaa
    35341 atgcatacgc atctgtattt gccactttga ttcgtataaa gctaacaact cctaactcct
    35401 ctcatttaat agttgctctc ttttttattc agatacattt ttgctgatca cagcctagta
    35461 tttcaatggt tttgaacact aaaccaaatt gttccattac aacattcact ggctgatgaa
    35521 atggattaat agatttcgat tattcaaagc gattttctat tggtggattg tgttcccaac
    35581 taacaagacg gattccaaag tcattatata actcttcaag agttaaccct ttcctgttcc
    35641 caatagatgt atctctccca cgctcgatat aaaatatgga gtttcgaatg ccaagacctg
    35701 gcaaatcttt ccttgttaca gttacactgc tactaacttc cccatataaa atccagctcc
    35761 tccaaaatga taatatattt ttcgaccatc atctaactca tgtaacaata attgttgtgc
    35821 cctcttgtca ctcgccaaat gcaaacgcca cgtgcgatac catgccatgc tacctgcatc
    35881 tgcagaaaat ccatcaaata atgcaacaat tgtatcttct atcacaatcc tttccccatc
    35941 tacttcatat tctaatctaa aatcaaactc ccctcgggta atcgcaggtc ttggtggctt
    36001 aggacccaat attattctac ttaaaaccgc attcgttccc agatgaaaca cagctataac
    36061 aacaataatg attaatattt tgtttctatt tgataaattt ctcattattc gcaaatcacc
    36121 tctacattct cacatactag ttcgtaatac tcctttaata tcaaaatatc tactgatcgt
    36181 aataatattc gctatgaatt cctactactc gtataagaaa ggccaaatca tcagctttta
    36241 cttgctgatg atttggcttg tttctattta tcgtaattgt tttctaatca ccaaaattgt
    36301 taacaatcgg ttcagatatt tcccaattca ctagccttat attatattga tttaacaatt
    36361 cttcttcatt tattgtattt tgatcaagcg gaccaaattg ttctaataat tctttgtcat
    36421 gtaaaatatc ccttctagta atgcctcttt ccctttcaat gaaagaagca ctaggaaaag
    36481 tatgattata accattcaac ctatctccca tgtaataatt agcaggtcct ggaaaataaa
    36541 atatttgctt attatcacta acttctaaca gcaacactaa atcttctccg ctggctaaac
    36601 gacttgtcca tctacgatat ctccctatgc cttcgttcat tccaaatcca tcaaattcaa
    36661 ctattaacgt gtcttctatc acatgtaatt cttcattcaa ttcatactca agtctaaaag
    36721 gaaattctcc atatgtaatc tctggcaatg gtggtgctgg agttctccaa ataaatacaa
    36781 taactgtgaa tagaaaaaat ccaacgatcg atataaatgt tatgagacct gctcgaagta
    36841 aaacccgata taataaaaat gctgtatttc gctttgctat atctagaaaa ataaaaagta
    36901 ctgcaatcat aatgatagta aaagttgtaa aaaaacgcat ttttgccctc cctttataaa
    36961 catcgattct caaattctaa accaaatctt ggtagttcaa gttcaggtat aacgtattcc
    37021 aaccatacat ctcaattact atttatgaac ttatgattat cactgaataa atcactccat
    37081 ccccttgtta aaacttctac attaattaca cctggttgtt ttcgactagc taatccaatg
    37141 aacttatcaa ccatccttat ccaccaacca cgagaatctt gaccagaagt aagaagagca
    37201 gttctcaagg atgatcgagc agttccttcc agttttttaa ttaatcaggc cagttataga
    37261 taaatacttg atcttatcta tatcaggact tctatattaa gcaaaaattt atgtacaaaa
    37321 ctaaaatctt cattcagttg tctccccgct ttttatacga ttgtattaaa aacaatagaa
    37381 gcctttccaa attatgttac tccagtaaag atggaattat agtttgacgg aagaaaagca
    37441 agtataactt ttaaaaaaaa ctgatacatt cgcatctcct gcttcatgta tcagtttttt
    37501 ctttggatta aactgcttct tcacgcagtt tttccgcaaa ttcatttatt ttgcgaattc
    37561 ggtgattaat tcccgatttt gatatcgcac ctgagggaat catttcccct aattctttca
    37621 agctgacctc tggatgttga agccgaagtt ctgcgatttc ctgaagtttt tcaggaaggg
    37681 catgtagacc gacctttgct tcgatcaatt cgatgttttc gatttgttta gaagccgcat
    37741 caatcgtctt gttcagattt gctgtctcac aattgactag acgattgacc gaatttctca
    37801 tatcccgtac gattcgaaca tcttcaaatc ggagcattga gttggttgca ccaatcaatg
    37861 ttaagaaatc agcaattttt tctgctcctt ttaaataaga aatatagcca ttgcgccgtt
    37921 caagcgttcg agcatgtaga ccgtaataat ttaacatatc gcaaatgtct tggttatgct
    37981 gttcataaat agaaaatatt tccaaatgat aacggctcgt ttccggatta ttgactgaac
    38041 ctgaggccat aaaagcacca cgtaagtaag aacgcatttt ttgcgaattt cccataatct
    38101 cgtccgaaac gtgtccattg aacatcatac catccatgat atcaagatcc atcaacacat
    38161 cttttgtgcc ttgcttcaac cggacgatat agacattgtt cttttttaat ttcatttttt
    38221 tacgaacgag tagctcactt cgtacctgat aatgatcttt caaaagagaa tagatacgtc
    38281 tggcaattgc agcattttct gtttggacgt tcaaaataaa ctgctggttc acaataccta
    38341 aagagccgtt cattcgcagc aaagcagcta attccgcttt cgcatgttct cgatgaactt
    38401 ccaaaccagt tagttctttc ttcacatctg cagcaaatga catcctattc tcctcctttc
    38461 tccaacaata aattgcttaa tattttgaac cgaaaactaa acggaacaat tcttctacta
    38521 ctttgtctcc atcgtggaag acaccaccat ctttcaattc caaaaagtcg gtggaaatca
    38581 ctcgacatcc ttcatttctc aatccgttga agtcgtgtgc gacttgtact agatactcat
    38641 catagatctc tgggtccata taatcttcag gcactttttc cgtattgacc aatactgtat
    38701 cgataaaagg ctgattcaaa tgcttgtgta aaacacgtat atgatcggca tctgtgaaat
    38761 gttccgtttc ccctttttgg gtcatgatat tacagatata gacggtttca gcagttgtct
    38821 tgagcattgc ttcgccgatt tctggtatca ctaaatttgg aaggatactg gtgaataaac
    38881 ttccgggtcc caaaacgacc atgtcggcgt ccataattgc tgaaacgact tttcgagccg
    38941 ctttggcttc acttttatca tttgtgttgc agacatacac acggtcaatg gttttacggt
    39001 cgatcgcgat tttagattct cctactgcag tcgttccgtc tttaaagaca gcatgcaagg
    39061 tcaaaggagt ttctgaagaa ggataaacat gtccatctac atgcatcatt tttgctaata
    39121 attgaatcgc ctcataagtg cttccccgca tctcggaaac tgcggcaatg atcagattac
    39181 cgatcgtatg attggctaaa aactgatctt cctttttgaa acggtattgg aaaatatctt
    39241 catagaattg tggcatatcc gataacgcca ctaagacatt tctcaagtca ccaggaggag
    39301 ccatagcgat cgattctctg attgcaccgc tgcttccccc atcatctgca acagtcacta
    39361 ctgctgtgat atctgctcct tgatttcgca aacttttcag gataactggc agaccagtgc
    39421 caccgccgac cactacgatc tttggttttc ttatccggta ggttttcatt ttcacgaccg
    39481 gttcaccgtc tctttccttt tatccttgtc ccgatgtgtc acattgactt tatagttttt
    39541 ccctaaagca tttgccaaac gttcagtcaa tgccacagaa cggtgttgac cgcctgtaca
    39601 gccgattgca actgtcaagc tgctttttcc ttctttaatg tatccaggca atacagtttc
    39661 cagaagatcc aaaaatttat ggtagaatga ttgcgtttca tcaaaggaca tcacataatc
    39721 atagactggc tgatcttttc cggtcaatgg tcttagttcc gggatataat gagggttggg
    39781 caaaaaacgc acatccatca caatatccga atcgatcggc aacccgtatt taaaaccaaa
    39841 tgatacaaat tcgatccgaa atccttggtc tccctttgat ttgaatgact cattgatttt
    39901 ttcacgtaat tgtcgtggtg tcaatgtcgt cgtatcaatg atcacggaag cttgggcttt
    39961 caagtcgtct agtatcgccc gttctttacg tatcccttca gtgatcaaac cgtccatcgc
    40021 cattggatgt gctcgtcttg tttctttgta gcgagccact agttcttcgt ctgaagcatc
    40081 taaaaataag atagaagtgt cgatgaagtt cgtattttcg atttcgatca gcatgttttg
    40141 gatttcttca aagaaggaac gagaacgtaa atccactcct aaagccattt ttgtgacttt
    40201 gcctgattct ttgattaatt cccagaattt tggaatcaat cgaggcggca tattatcgat
    40261 acaaaaatag cccatatctt caaaactttg gatagctact gttttccctg caccgctcat
    40321 acctgttatg atgactaatt gcaaattatc tgtcataatt acgaactcct ctcacattgt
    40381 gcatagtaaa attatatcat tccgggcgta tcattaccag ttttcttttt cttttacaaa
    40441 aagatttgga ccaaatatct tttaggatat ttgccccaaa tccaattttt ttacttttcc
    40501 gatgctgtat ccaatgcctt gcttctttca gctagcgctc gttcaatcgt ccgatctgct
    40561 aaaatagatt gggcatcgat cactggataa tggttatctt cagcaaattc atgcatcaat
    40621 gacaattctg tgcaacctaa gataactttt tcacagttta ggcgctctac cgcttcttct
    40681 aagatttcgt aatatagctc ttgattcaaa taatccgatt ccttgatctc atgatagatc
    40741 agataattga ttttttcttg aagaacagta tcaggaatca ctgtttcgaa tccaagattt
    40801 ttgacttcgc gttcatagat tccagctttc atacttcctt ctgttcctag aatcgctact
    40861 ctccctgtcg tatgctgacg gacaagttca tttgctgctt ctcttggcat atgaaggata
    40921 ggaatatccg ttgccgcttg taattcttca aaaaagtagt gtgcggtgtt acaagtcaac
    40981 acaatgaagt tcggctgcaa taaattttgt ttctcaatat catccagcag aaacggcatt
    41041 ggattttctt ctgatcgatc taaaatataa gctgtacgat caggaactgt tgcatgattg
    41101 aataagacat aattcaaata ttcttgatct tttgtagctt tcgttcggtg gttgatcaag
    41161 cgaacaaaac tttctgtcgc catcgtgccc attccgccta aaatactgaa aaaattctcc
    41221 atgaactagc cttctttcac atgaaaatac tttttgaatc ttggaatata gttatggaac
    41281 atatatttca tcaacaacca gcgcttgatt gaccggtctt tttcataaaa cacagtagta
    41341 ccgtaacgat tttctttgat catttgctca gctagttttt tgtcttcatt ttcccgagca
    41401 tattctaaaa agattttttt gggcacaccc atccataatc ttgctttatc tgattgattc
    41461 gttccatagg tcgtttcaac aaagggtttg ttaaacactc gatcttctgt gacgaaacga
    41521 gccagattca agccgttcaa tgtcacaaag aaactgctac gaccttgtct caaattgatt
    41581 tcaaataatt tatattctcc atctctagga tcatacttca tatcgaaatt ggcaaagcct
    41641 gtatattcga ttttttccaa aaatgcctta atggtttgat agattttttc gttataatct
    41701 ggcatgatca caacgtaatt accaatcgat gctggtgtag gatcttctaa cagtggatga
    41761 ccaagacaca tcatccgaac ttgatgatct tcatctacat acgcatttag cacacgcata
    41821 ttactatcat cacccgggat aaaatcttgt acaatcattt cacttttata accggcttcg
    41881 tatatccggc ctaaaattaa atcgaactct tctctagtct ctaaaataaa agcttttttt
    41941 cttccttcaa attggacaga aagatactcc acactgtttg caggtttcaa agcaactggg
    42001 aattcaaaag gcaattcctg ttccaaatgt ccatttacta acatttcttc tctgacgatc
    42061 aatgttttag gatacggaag atcatattct tcacaaactt cataaaagct tactttattg
    42121 atcagtcttt caaataaaga ataatcaata tatggacaga taaaatattc tgacagctct
    42181 tgtttatgtt gggagatcaa ttctgcatat ccatcaccac aagcaatcaa aagatatttt
    42241 ttactcttat cagaatatct ttcttttgcc aaacgaagca tcgtctcgat aaacacaggg
    42301 tctttatcaa atcctggaat aacttctaca ttgacaattt tactgtagcg ggtaggggct
    42361 aactgatccg aagcatatgc ttggcagatt ttgccgtatg cttcattaaa agaacgtgcc
    42421 ataccataaa cgttcatgtc gcttcctaat aatataggga taaattcttc attttcaata
    42481 ctgttcatca ttatctctca cttactcata atctcttgtt tttcttttcc aactacacaa
    42541 ggaatatcat accataaaga aaaaagcaat caaaggaaac tcctccgatt gctcaattct
    42601 tttttgaacg gattgaactt ataggaagtt tttgtctata ccaatcagtg tagaaagaac
    42661 taccatgtaa tgattctaga acactgatat taataaaaca agcaaaaatt cattttttta
    42721 tgttttttta actatctcag ctatctatcc tctttatacc attatttttt tcaaatagtg
    42781 acctgtataa ctttctttta cgttaatgat ttcttctggt gttccagtcg caaggatcgt
    42841 tcctccacct tctccacctt ctggtcctaa atcaatgata taatctgctg ttttgattac
    42901 atctagattg tgttcaatca ctaaaactgt gttaccagca tctactaatc tttgtaatac
    42961 atgcaacaag cgggcgatgt catcgctatg aagtcctgtc gttggttcat ctagtatata
    43021 gaaattcttt ccattagaga ttttgtgcaa ttcactggca agtttcatcc gttgtgcctc
    43081 accaccggac aatgtcgttg ctggttgccc catcgtcaca taacctaagc caacatcaac
    43141 aatcgtttgc agtttgcgat gaatctttgg aatgtgcttg aagaattcta cagcatcttc
    43201 tactgtcatt tccaaaatat cagcaatgct ttttcctttg taatgcactt ctaatgtttc
    43261 agagttatat cgtttgccat gacatacttc acaaggaaca tagacatcag gcaaaaagtg
    43321 catttcgatc ttaataattc catccccgcg acaagcttca caacgaccgc cttttacgtt
    43381 gaaactaaaa cgccctttct tataaccccg catttttgcc tcgttcgttt gagcaaataa
    43441 cccacggata tcatcaaata cacttgtata agtcgctgga ttacttctcg gcgtccggcc
    43501 gattgggctt tgatcgatat cgatgatctt ttcgatactt tcgtagccgg aaattgtctt
    43561 gaatttacct ggcttagcag aattcttatt taatttttgc gctaacgatt tctttaagat
    43621 actattgacc aatgtactct ttccagaacc agacacacct gtgactgcta caaattctcc
    43681 taatggaaat tcaacactaa tatttttcag attgttttct gaagcaccag tgatcttgat
    43741 tgctttccca ttacctttac ggcgttcttt tggtacaggg attgattttt tccctgaaag
    43801 atatttccct gtcaaagaat tttcatcatt agctacttct tcaggagtgc ctgcagccac
    43861 gatttgtccg ccttgttctc cggccccagg tccgacgtca atcagataat ctgctgccca
    43921 catcgtatct tcatcatgtt cgactacaac gagggtgttg ccaagatcac gcattttctt
    43981 taatgagcca atcagtcgat cgttgtcgcg ttgatgcaat ccgatcgatg gttcatctaa
    44041 aatatacaaa actccagaaa gattcgatcc aatttgtgta gccaatctga ttcgctgcgc
    44101 ttctccccca gataatgttc cggaagcgcg actcaaagtt agatagtcta gtcccacatt
    44161 ttccaagaat gaaagtctgt catttacttc ttttaaaatc ggtttggcaa ttactttctc
    44221 ttgttcagat aacgttaagt ttgagaagaa atctactgct ttttgaatag acaactcatt
    44281 tgtttgcccg atattcgttc cattgatttg aacagataga gcttggggat tcaatcgata
    44341 acctttacat gtctgacaag ttaattctgt catataaaga cgcatttgct cacgcgtgaa
    44401 atcactgttc gtatcatgat aacgacgctc gatattcttc aatacccctt cgaaagtcgt
    44461 ttctacatcg cgaacgccac caaaatcatt ttcataatgg aaatggaaaa gatcatctgt
    44521 cccattcaag atgatatcct gatgctcttc cggtaattct tcgaatggtg tatctaaatc
    44581 gataccgaaa ctttcacaag cctgcgctaa catttgagga taatactgag agctgattgg
    44641 attccatgga acgatagcac cttgactaag tgtcttcgtt ctatctggaa tcactaaatc
    44701 ttgatcgact tctaatttga cacctaaacc atcacagtct ggacaagctc caaaaggcgc
    44761 attgaatgag aacagtcttg gttctagttc gccaacagta aatccgcaat aaggacaggc
    44821 atagtgttcg ctaaacaaca tttcttcttc accgatcacg tcaaccagag catagccgtc
    44881 tgccaatcgc agagccgcct ctaaagaatc aaatagacga gaacgaatcc cttctttcac
    44941 aatgatccgg tcgatgacga tcgcgatatc atgttttttg tttttctcca gctcaggcac
    45001 ttcacttaaa tcatagatct caccatcgac tcgaacgcgg acgtatccct ctttttggat
    45061 tcgttcgaat atttttttat gttgtccttt tttctttacc acgatcggtg ccaacacttg
    45121 gatctttgtg cgctcaggca aagccattac ttgatctgcc atttgatcta ctgattgact
    45181 ggtaatctcg atatgatcgt tgggacaaat cggatgtcct acacgtgcaa acaacaagcg
    45241 taaatagtca ttgatttccg tcacagtacc tactgtcgac cgaggatttt tacttgttgt
    45301 tttctgatca atagaaatcg ccggactcaa tccgtcgatg ctatctacgt ccggcttatc
    45361 catttgtcct aaaaactgac gagcataagc agaaaggctc tctacgtatc tccgctgccc
    45421 ttcagcgtac agcgtatcaa atgctaggga actttttcca gaaccggaca aacctgtaac
    45481 gaccacgaat ttatctcgtg gaatcgttac atctatattt ttcaagttat gggcacgtgc
    45541 accgtgaatc gtaattttat cgttagccat gttgtcctcc tactttgaag cttttaattc
    45601 taaaatcata tctcgcacat tagcggctgt ttcaaaatcc aatgctttcg ccgcattttt
    45661 catttctttt tctaatttca tcaataacgt atctttttct tctttcgtca tttcttcata
    45721 cgagacttgt accgcttctt ttgtatcatc ttccgattct ttcgtaatag aaatcaaatc
    45781 tcggatttct ttaatgatcg tttttggaac gatcccatgt tcttcattgt acttctgctg
    45841 aatcgtacgg cgtcttgatg tttcatccat cgctagacgc atagaatctg ttactttgtc
    45901 tgcgtacatg attactttac cttcttcatt ccgagcagct cgtccaatcg tttggactaa
    45961 ggaacgttca ctacgtaaaa agccttcttt atccgcatcc aagatagcaa caagggaaac
    46021 ttcaggtacg tctaatcctt cacgaagcaa attgattcca actaacacat caaattcacc
    46081 taatcgaaga tctcgaatga tttctgttcg ttccagcgtt ttgatatcac tatgcaaata
    46141 tttgactttg atccctaatt ctttgaaata atctgtgagg tcttctgcca tttttttcgt
    46201 caatgtcgtt acaaacaccc gctggtcttt ttcgactcgt tcatttattt cgcctactag
    46261 atcatcgatt tgtcccatga ttggacgaac ttcgatcact gggtcaagca gccctgtcgg
    46321 acggatgatt tgttggataa cggtatctgt ttgttcatgt tcatatggtc ctggcgtcgc
    46381 agagacataa atgatctgat tgacatgttt ttcaaactct tctaaccgaa gtggccgatt
    46441 gtctaaagca gatggcaaac ggaaaccgta atctactagc atctgttttc tcgctcggtc
    46501 accattatac attcctctga cttgaggcat ggttacgtgc gattcgtccg ccacgatcaa
    46561 aaaatcttca ggaaagaaat ccaatagcgt ataaggcggt tcaccttctt tacgtccgtc
    46621 catatgccga gaataatttt caattcccga cgtgtagccc atttctaaca tcatttcaat
    46681 atcgtaattg gttcgctgtt ctaaacgttg agcttccaga agtttgtttt catttcgcaa
    46741 gacagttaaa cgctgttcta attccgcttt gatattcgct acggcatgct ccatatgttc
    46801 atcattcgtc acaaagtgag tcgccgggaa gattgccacg tgttccgttt ctcctaaaac
    46861 ttcacctgtc agtgcattga cttctcggat acgttcgacc tcatctccaa aaaactccac
    46921 acgtaaggca cgttcatctc ttgaagccgg aaaaatctcc acgacatcac cgcgcactcg
    46981 aaaacgaccg cgctgaaaat ctatatcatt tctttcgaat tggatactga ctaagtcacg
    47041 aatcaactga ttgcgatcta gttctgctcc ctgtcgaatc gaaactactt gtttttggta
    47101 ctcaaaaggc gaacctaatc caaaaataca tgaaacggat gcaatgacga tcacatcatt
    47161 tctttctaat aatgaactag tagccgaatg tcgtaatttg tcgatctcat catttacact
    47221 tgaatctttt tcgatatacg tatcgcttga aggcacataa gcttcaggct gataataatc
    47281 ataataagaa acaaaatatt caacagcatt gttagggaaa aattccttga attccccgta
    47341 cagctgacca gccaatgttt tgttatgggc aataattagt gttggtttat tcactttctc
    47401 aataagattg gaaatcgtat atgttttccc tgttccagtc gcacctaata agatttgtgc
    47461 ttttttcccg ccgactacgc catccactaa ttggttaatc gcttcaggct gatcaccagc
    47521 cggttggtat ttcgagacaa gctcaaagtg tcgggaggta tctctctcaa tcattcttcg
    47581 tcctcctttt cattcattcc ttttcatttt acgaccaata aaaagaaaag gaaagcaaag
    47641 gcattcctta ctaaaaaatt ataccacacc gaacatactt tcgccacttt tttatcttat
    47701 tatgcatgtt acgttttata acataaaatg ttagaaactc gcattttttt cattttttcg
    47761 agcttacagt cttgtctgat tcagcacttt tcgcctataa taataaaata ttggaaattt
    47821 aggaggttga ttatgaaaag aaagcattta tttcactcat ttgttttctt aatgacagga
    47881 cttgtgacac ttgcgtttgg acatgttgca caagctgaca acactacaac ggcagagtca
    47941 agcacaagcg agacaatgca aaaaatagag cccaaaaaag acgtatacgt aattgccagt
    48001 gactctgctt ttgctccatt tgaatttcaa aacgcaaagg gcgagtacga aggcatcgat
    48061 gtaaaattga tggaaaacat cgccaaactg caaggattta acatccgaat ggactaccgt
    48121 ggtttctctg ctgctttgca agctttggaa tcaggacaag cagacggaat gattgccgga
    48181 atgactgtaa cagatgaacg aaagaaaagc tatgattttt ctgattctta ctttgatagc
    48241 gggatccaat tagctgtcaa aaaaggagat acttcgatca agtcttatga agatttgaaa
    48301 ggaaaaacag tcggagcaaa agttggtacc gaaagtgctg aatttttaag cgaccatgaa
    48361 tctgaatatg gctattctat caaatatttt gatgctgctg atcaattgta cgacgggtta
    48421 aaagttggcg caatcgatgc aatgatggat gattatccgg taatcggtta tgcgatcaaa
    48481 caaggacaag aattggaaac accgatcaaa aaagaatctg gcggaaaata tgcatttgcc
    48541 gttaaaaaag gacaaaatcc tgagcttctt aatatgttca atgaaggatt gaaagaatta
    48601 aaaagaacag gcgaatacga taagattatt aaagaatatg tagcggatgg ttcagaaact
    48661 tccagtgagt cttccactgc tgatgaatca acatttcttg gacttatcca aaacaactat
    48721 caagcattgt tgaaaggact ttggagaaca attctcctaa ctttgatctc ctttgctttg
    48781 gctatagtaa tcggtgtgat ttttggatta ttcagtgtag caccaatacg cgctcttcgc
    48841 acaattgcta gtatttatgt cgatatcatc cgaggaattc caatgatggt tcttgcgttc
    48901 tttattttct ttgggttgcc tggtatcgtt ggatttacga ttcctgactt ccttgctggt
    48961 gttatcacct tgactcttaa cgcaagtgct tatatcgcag agattgttcg aggcgggatc
    49021 aacgccgttc ctgtcggaca aatggaagct tccagaagtt taggtctttc ttataatcgg
    49081 acaatgcaaa aaatcatttt gccgcaagcg atacgcatca tgatcccatc attcgtcaat
    49141 cagttcgtta tctcattaaa agacacaacg atcatttccg caatcggtgt agtcgaattg
    49201 ctgcaaactg gtaagatcat tgttgcacgt acaacacaaa gtacgtatgt ttacttgatc
    49261 attgcgatca tgtacttgat tttgatcaca gcattgacaa aattagcaaa agttttagaa
    49321 aagaaggtga agtaagatgg cagaaaaaat cttagttgag catttagtca aaaaatacgg
    49381 cgataacaca gtattaaacg acatcaatgt gtccatcaac gaaggagatg tcgtctgtat
    49441 cattggccct tcaggttcag gaaaaagtac atttttgcgt tgcttgaatc gtttagaaga
    49501 accttctgac ggtgaaatta ttattgacgg cgcccacttg atggataaaa gcacagatat
    49561 caacttggtg agacaacata tcggaatggt attccagcac tttaacctat tccctcatct
    49621 ttctattttg gaaaacatca ttttagcacc gatggacctg aagaaagaat ctagagaaga
    49681 agcagagaaa aaagcaatca aattgctgca gacagttggt ctagaagata aaaaagatat
    49741 gtatcctgaa atgctttccg gtggacaaaa gcagcgtgtg gctattgctc gtgctctagc
    49801 gatgaaccct gacatcatgc tttttgatga gcctacatct gcactcgacc ccgaaatggt
    49861 cggtgatgtc ttgaacgtca tgaaaaagtt agcagaacaa ggtatgacga tggttatcgt
    49921 tacgcacgaa atgggcttcg ctaaagaagt ggccaatcgt gtcatgttca ttgacgacgg
    49981 aaacttttta gaagacggaa cgcctcaaca aatctttgaa aatccgcaaa atgaacggac
    50041 aaaagatttc ttgaataaag tattaaatat ttaataaaaa ccaaaaatgc ccggtcgctt
    50101 catgacgacc gggcattttt agtttcttgt tttttcactt aactgtacca gccgcatcgc
    50161 ttgttctcct gcacaaacaa gcaatcgctc tacctgttcc atcgcataag aaagtaccat
    50221 cggttcattg acgatatcaa gtacatagtc gataccacct tcagaaacta tgatgattat
    50281 cttattctaa agctggcttt tttgttggta caaacatgac aactacaaaa aaaccaggcg
    50341 aacgtatgat tgttcgtctg gtttttaatt attaatgact tagcgttttt actagaaata
    50401 gaaaatttgg gcaagtctac tttatatttt tactagaaaa actacttccg ctttttcccg
    50461 ccaaaagcat ctttaaactt atcgaagaaa ccgtcttctt gctgttcttc aactttgatg
    50521 ccgccagctt cagcgaatgc acgtaatgct tctctttgtt gttcatttag atttttcggt
    50581 gtgatcagtt ttactttgac atgttggtcg cctgttgcac caccacgtaa cttcggagcg
    50641 ccttttccac gtaaacggaa gttcgtacct gtctgtgttc cagcagggat cttcaatttc
    50701 acatctccat ggacagttgg tacttggact tcatccccca aagctgcttg tacaaaactt
    50761 aaaggcaatt catagtaaat ttcagaacct tcacgatcaa agatatcact ttcttctaca
    50821 cgaaaaacca catacaaatc accaaatggt ccgccgtttt ctccagcttc tccttgacca
    50881 gctaaacgca tttgttgtcc ttcttctaca ccagctggta cattcacttt aactgaatgt
    50941 gctttcttct catgtcctga gccatgacag gttggacaag gttctttgat ttctttccct
    51001 gtgccatgac aaacatcaca agtttgacgg ctcatcactc gtccaagtgg cgtttggcgt
    51061 tctacattga tcgtacctgc accatgacat ttatgacaag tagttggttg tgtgcctggt
    51121 tttgcaccgt ttccaccaca agtatgacag atttcttccc gattatactt gatttctttt
    51181 tctacaccaa aaatcgcttc ttcaaaagac aagtcgaccg tatattgcaa atcagcacct
    51241 tgacgaggcg catttggatc gactgaccga ccgcctcctc caaagaaaga gtcgaagata
    51301 tcttcaaaac caccgaagcc gccaccagag aagccgccga atccaccaaa tccgccacca
    51361 gctccaccag caccgtaatt tggatctgtg cctgcatgcc cgtattggtc gtatgcagcg
    51421 cgtttttgcg ggtcacttaa aatctcatat gcttctgata cttctttgaa tttttcttcc
    51481 gcatcaggtt ctttattgat gtcaggatgg tattttttcg aaagcttacg ataagctttc
    51541 tttatttcat cttctgatgc tccttttgag agccctaaga cttcataata atcacgtttt
    51601 gttgccatag gctttcctcc tattggttct catcattttc acgtcgcttg ttatcatatc
    51661 atattttgtt tgaaacaaaa accgatactt caaactattt ttcaaaagaa aaagccaaag
    51721 tagcaacttt ggccttctct cgaaattcag tgaactgatt atttatcgtc gccatcgact
    51781 tcttcaaaat cagcatcaac gacatcatct gctccgcctt gagctgcttc tggattttct
    51841 tgagcttgtt gttgtgcagc ttgttcgtat agtttaacag tcaagttttg aacgatttcg
    51901 ttcaatgcat cgcgtttagt tttcatttcc tcgatgttgt ttgcttcaac agcggctttt
    51961 aattcgtcac gagctgtttc tgcttttttc acttcttctt cgtccacttt gccttctaat
    52021 tctttcaatg ttttgtccac agagaatagc aatgcgtcta catcattacg taggtcaact
    52081 tcctctttac gagctttatc tgcttcagcg tttgcttctg catctttcac catacgttcg
    52141 atttcttcgt ctgttagacc tgaagaagat ttgatcgtga ttttttgttc tttttgtgta
    52201 cctagatctt tcgcagatac atttacaatc ccgtttttat caatatcgaa tgttacttcg
    52261 atttgtggaa taccacgagg agctgctgga atatctgtca attggaatct tcctagagtt
    52321 ttgttgtcag cagccattgg gcgttcacct tgtaatacat ggatgtctac tgctggttga
    52381 ttatctgccg cagttgagaa tacttgtgat ttacttgttg gaatcgttgt attgcggtca
    52441 atcaatttag tgaacactcc acccattgtt tcgataccta atgacaatgg tgtaacgtca
    52501 agtaaaacaa catctttcac atcaccagtg atcacgccac cttggatagc agcacccata
    52561 gcaactactt catcagggtt aactgatttg tttggttctt ttcctgtttc tttacgtact
    52621 gcttctacaa ctgcagggat acgagtagat ccaccgacta aaataacttc gtcgatttct
    52681 gattgtgaca gacctgcatc ttttaacgct tgacgtactg gtacttttgt acgttctact
    52741 aagtcagctg ttaattcatc aaattttgca cgtgtcaatg tcatttccaa atgcaatggt
    52801 ccagattctc ctgctgtgat aaatggcaag ctgatttgtg tgcttgatac gccagataaa
    52861 tcttttttcg ctttttcagc agcgtctttc aagcgttgta aagccatttt gtcttgagac
    52921 aagtcaatgc tgttttcttt tttgaattct gctaccatgt agtcgatgat tttgttatca
    52981 aagtcgtccc cacctagatg gttgtcgcca gctgttgaca atacatcaaa gacaccgtct
    53041 cctagttcaa ggatagatac gtcaaaagta ccgccaccaa ggtcgaatac taagattttt
    53101 tcgtcgcgat ctgttttatc taaaccatag gcaagagcag ctgcagttgg ttcattgacg
    53161 atacgttcta cttctagacc agcgatctta ccagcatctt ttgttgcttg acgttgtgca
    53221 tcattaaagt aagctggcac agtgataact gctttttcga ctttttcacc taaatagtct
    53281 tctgcgaatc ctttgatata ttgaaggatc attgctgaga tttcttgtgg tgtatatgat
    53341 ttaccttcta catctacttt gtaacctgct tcaccgatat ggcgtttgat tgatgaaatc
    53401 gtatttgggt ttgtcacagc ttgacgtttt gcaacttccc ctacttggat ttctccattt
    53461 ttgaatgata caacagaagg tgttgtacgg tttccttctg ggttagcgat gatttttgct
    53521 tcgtttcctt ccaatactgc tactgcagag ttagtcgtac ctaagtcaat accgataatt
    53581 ttactcataa ttaacgtctc cttctttaat tgaaagtgta agttttatat ccgcacaatt
    53641 attgtgcaac aatgaccata gttggtctta acacgcgatc atgtaatttg tagccttctt
    53701 gtagtacttc tacaatcgta tcggctggtg tatcttcagt cgctggaaca gtttgtactg
    53761 cttgatgaag attaggatca aaggcttctc ctttagcagg gattttttca attccttctt
    53821 cttccagtgc gttacgcaaa ctttccaaga ccatttccac gccttttttc aaacctgccc
    53881 cttgatcatc tgacacttct gtggctaatg cacgttccag gttgtcaatt gatggaagta
    53941 attttttggc taaatcttgt gaacggtatt tttgtaattg ctcacgctca ttttttcctc
    54001 gatttgccat atttgcgatt tcagcacgag cccgcaagta tttatcttcc atttcttcta
    54061 actcagcttt taatttcgct gtttcgaatt cttccgcttc agcttctgaa atacccgaat
    54121 cttctgcagc ttcgacatcg atttccggtt ctggctgagc atctgtcatt tctttatcta
    54181 gttcttcttg attttctttc acgatacagt cttcctttca ttattcagtc agctgtttga
    54241 ttgctcttac taagaaagag agaacgatca gctgcaaata gcttcgttat tcacattacg
    54301 agtttgacaa gtcaagcgag cggtagtaat cagcaagttt agctgctagt tctcttcgat
    54361 aaacatcgac tagaccgaac atccgagaat aaggcatact agtaggccct aacaaggcta
    54421 ttgtacctct tccatgacca tctatctcgt aacttgcttg aatcatactc atattctgca
    54481 ataaatcatt gcctaattca gcaccaatct tgatatgaat attgctatcc atcggagtga
    54541 tcatttgtgt aagtccgtct gagtctttca taaaagaaaa catcgatttg aactgatcaa
    54601 gatcttgacg gggctcataa tccaagagat tcatttgtcc actgacataa accttttctt
    54661 caaaaacatg accaagaacg gtgtcaaata actgagacat cccttctgtc gtctggaaat
    54721 atttatgaag aatcatcgga atctccgtac gaagtttatg gtacaccgtc atcagaggat
    54781 ctccgactag acggtcgttt acaatctgta ccattttttc tagttcctga cttcccatat
    54841 attcgggaag agtgaacact tggctttcta cattccccat atctgttacg acgatagcaa
    54901 taatctgtcg attattcaag ggtacgatac gaaagccagt cagtcggcgg tcttttattt
    54961 caggtcccaa tgaaaaagtc gtatagcttg tcagctcaga taatatctca gcagattgct
    55021 taataatctc attgatttca tgaaattctc tgcctagaga ctgacgaatc agcagcaaat
    55081 catcttctgc tacgcgagca ggttttaaca aatgatccac gtaataacga tagcctaaag
    55141 cagatggaat ccgcccagaa gaagagtgag tcttcaacag caatccttca tcttctaatg
    55201 ctttcatatc attgcgaatc gttgctgagc tggccttgac tccctcagac attaatgttt
    55261 tggaaccaac gggcacgcca ctactcgtat agtgttggat gatcagacgt aaaatgtcgt
    55321 tttgtcgctt tgttaacatc ttcctcacct ctcattagca ctcatatatt ctaagtgcta
    55381 attcacttat aaatatagca agaagccctt ctcctgtcaa gagaaagact ccatttttta
    55441 gcactctaaa cacaagagtg ctaattctaa ataattgatg taaatccagt tatatcaata
    55501 cttcaatacc tcattgtcaa actttctaaa ctttttcttt tcaagtttcg ataaaaaaca
    55561 aatattcttc aaactatttt tcaaataaaa agcgctcaaa cacattgttc cccaaaaaag
    55621 tccctcttgg tgtcaaataa acacggtctt cttcattaac aagtaaccct tcttgctcta
    55681 attcccttag cacatcaccg tacaccgatt caattgtttt ttgatagcga tcatagaaat
    55741 gttttttagt aatccctgtt ttttttctta gtcctaagaa catttcttct tctatttgat
    55801 tttttcgtgt caatttttct tcttccaata ccgggcgttc atttgctcgt aatgggcgta
    55861 aatagtgttg gattggtcct ttgttgcggt aacgaatatc tccaagataa ccgctagcac
    55921 cagctccaaa cccaaaatag tggtcattgt tccagtacat gaggttatgt tgagattcat
    55981 gtccggagag cccaaagtta cttatttcat attggtgacg tccatgcttt tccattgctt
    56041 caatcgtctc ttcaaacatt ctggtttccg tttcctgatc aggcagttcg agtcttcctt
    56101 gtcgtaccca gttcatgaac attgttttgt tttcgaggat caatgagtac aaagaatagt
    56161 gaggcagatc caaagccaaa gctttttcca aagtatcccg atatccttct agtgtttgtc
    56221 ccggtaatgc ataaatcaaa tcgatgctta cattggtaaa attttctgct tctaaaaatt
    56281 gcattgtttg atacacatct tctgcagtat gtttacgtcc aatttttttc aataagcgat
    56341 tgtcaaatgt ctgcactccc atggataaac gattgacgcc atagtttttc atcacttgaa
    56401 gtttttcacg ggtcaaatca ccaggattcg cttctacagt aaactcatta ccattttgaa
    56461 aaggcaggat ctctctagca cctgataata gtcgatcaag ttgtttagca gataaagaag
    56521 ttggtgttcc gcctcctaca taaagtgttt ccaaattcgc tgtaggatga ctttccagca
    56581 ttaatctcat ttcattcagc agcatttcca catactcatc tactggctgc ccttctaaaa
    56641 aaactttatt aaagtcacag taatagcaga tatgctcgca aaatgggata tgaatgtacg
    56701 cagaaacctt gttttctgcg ggatttattg tttctatcat tgaaattctt tctccttacg
    56761 tcgaaaagtc gtgcctgttt tcgaccttct taaaatcgcg ttcaagcacc aactcattga
    56821 aataagccgc atatttagaa tcaaggaaac ctagctctaa aaatgcttgc ttattgtcat
    56881 cggagctaca cggtgctttt acagcctctc gataaacggt aatcgcaaag ctgaccttcg
    56941 gcattaagtc aaaatctgca aaaatatgaa aagctatttt cacagattcc tccttaagtg
    57001 ctcagaccac aacgctttgc ttacaacctc tcatatacgc atactaaacg tatttggcga
    57061 acaaatccac taaaaaatcc aagaatcgac ttcttggatg atttttttac actcatgatt
    57121 cttcctaaac aattttgtcc ttattttatt cataaaaaaa tctagtcaaa tctctcactt
    57181 caagagtttt aactagattc caattattat ttttttgtaa aaataaacag tctcttaatc
    57241 atagacattt cttcggtgcc ctacttgaat agcgataaca acgaattgat tatcttctat
    57301 ctctaccaat acacgtattt gccaatcaga gctgcttctg aatttcgggc gtgaatttta
    57361 aacggcaggt cattccagcc caccaaattc attaaggatt cttccatgaa tactgttgtt
    57421 ttcccacttc ttatccaatg tttatgggca atttcagccg tttgacgatt gtattcatct
    57481 tctagttgtt ccatcgaata gttttttaga agttcagata aagtaatccc ataaaattca
    57541 gccatataag aaagccattc ttttttggcg tcacttacac gaaccgtaat catagcccta
    57601 taattgcctc tcttaaagaa tctcatgcat ttcctgatgt gattttagaa aaatttactt
    57661 gctaaaaaac tgtgaaaatg taggagctag catccttgta gtaaatgatc gagctcttta
    57721 ttatacatta aaaaagttca gaaattttga tgaagtagcc aactactttt tcatgagtaa
    57781 agcaacacta gaaaaagaat cctccagtac ttagaattta ctggaggatg tacttttgaa
    57841 gaagcctata ggttatttaa aaaatattac tacaggaagg aacgagaatt acttcgttac
    57901 ttataataga acttagtctt atatagaagg catagctcac attagcttat ttgtcctata
    57961 aaaataaatt acggtatttt agaaaagcta ttttctcttt tttcaacgat cttcagcaat
    58021 ttttctttat cgtcaggtaa ctcaagttca tgaattctag catgacaatt gggacataac
    58081 gcgatacagt tttcaatcac atcttttcca ccttgcgaca aatattctat atgatgacaa
    58141 tgtaaataag gtacaccgtc ttttataaat ggcccttttt cttggcaaag ttgacaaata
    58201 ccttttgcaa gtcgtttaac atattcagat acgaagggat tacgtttata tatttttgtt
    58261 tttgagaagc aaaactcctc ttcgttaaca tattttgcag ccattttttt attataatta
    58321 ctaacttttc ttgcttcttc ctctaattta gcattagata aattacgaat atgtctagtt
    58381 tgattttctt cctggttata tatctttatc ttcaatcaat tgctcttgat ttattaaagc
    58441 taatggaaat ttatatactt ttctgctgtt gcccgaacta tctttttcat taacagtata
    58501 tatttgtcct gctaaatata cttctcccag atatgtgtgt tcttttggtt taaatgtttc
    58561 aaataaatga atctttacaa aattactttt tgaattggct aaaactttat tttgattctt
    58621 atccaatact tgatcccctt ttagccccat accggtatat tgtaaaatac catttaacca
    58681 cttatcttta taaacattac ttcctgtttg atcactaaac agtacaagag tattagtttg
    58741 atgagatctt ctcattccac cctgtttgga acatttaaac ttctctgaaa tttctttgtt
    58801 agtatatact ctaccaactt ctaactcacc taatatgttt ttagaccaat tttctcgcca
    58861 tgtaataatc ttatcaagat taaacatttc tccctctttt ggcatgccat ttctaattaa
    58921 attagctaat acaccagtag aaatatctaa tttttttagt aattctttct tagtaatcaa
    58981 tgttggattc ataacaatgc agctcctaat gatatcaata taattgcatt agataacttg
    59041 aaaaatcgaa aaaaactcat tttgtgtcaa gttatctgta atatataaaa atatcattat
    59101 tatacctcat ctatgtgaat ttttactatt cttaccttag catattcttt ataggtatat
    59161 cagagctaat caaactaaaa aatacccgaa gtcttcttat gtaaaaacac cggttattac
    59221 ttaaatatga cttaggtaaa acaatgagtg atccaattat aaaattttat ggcgaataat
    59281 ttagtaagcg ctacatattg aatgatttag aaattttgaa aaagtagcta gttcctttta
    59341 taccagaaaa gtaaacctaa taaaaaacac aactaatttt tagctgtgtt ttttaagtta
    59401 caataattat ctatttaata gtcttaattc attaaaataa aaaactcaac tttacaagga
    59461 tatggtttaa aaaatttatt tatccaaccc aactagtttt cgctgcttac gatttgcttc
    59521 atctgctacg taattcatta ctgttttaaa ttctttcgct gaggcgtttt ctgataaatc
    59581 agcgatactt ttattatact tcttcacgat ttgttgtact tgttctttct cagtcatgta
    59641 attcctcctc caactctttt gaagtatatt gtattggtag tactaattga atattatctg
    59701 ctgcataatg cacttcagaa atgtcgtttt gataatcctt aatcattatg tgaaggacta
    59761 cttcaggatg tctatttttg actttttcaa tattctctct ggacttaaaa aacgcattga
    59821 taaacatttc ttttggcaca tgacgtcctt cagctagttc acgttttcga gtgaaatccc
    59881 aggcaacttt gggatcttgg taaacataga aaatcgtaac gcgaaagtta tttttaaggg
    59941 ctcgaataat atttttctct gcactaagga tagcaaaagt atcctctagt atgaaagaat
    60001 agccatgttc cagtacatat tttaatgatt gttcaactaa ccaagaagaa gctttctgaa
    60061 aaacacttga gttctttcca ttgtattctg gaaattgtgc tctaaaatag tccgcatcaa
    60121 tcacaacatg gttgtcataa ttttaagcta aacctagtgc aacctctgtt ttacctgctc
    60181 ctgggcttcc agccatgaat accgcatctt tttcatcatc agggattttt cccttgatga
    60241 ttgtttcaat aaatttatct ttattgaccc tagcgtaatc taaatacttg tctttaggtt
    60301 ccaagattgc accttctttc cttcttctat attcatacta attatacgat atttatataa
    60361 aaaatataac ggtcatttta accatattaa catttagtca cagtaatagc agatatgctc
    60421 gcaaaatgag atatgaatgt acgcagaatc cttgttttct acggcattcg cttttttttc
    60481 attggactag ttatatattt ctagggttgt tttcatgtct gagtgcccga tatgatttat
    60541 ttttcgtttc tataattact ttttgccttc cagtttcttt taagattgta ctcaagcaag
    60601 tgggaattgg ttcttttgtc atccatgtat gcaaaatgtt ataatgctgg taaacaaaaa
    60661 tgattacctg tcatttttat ttagttcgta tttaattaag ttgactgtct gtatactctg
    60721 tctaaaactt aagaattgtt gttttcgctg tcgctatcca aatttaatga atgtctgtat
    60781 gttaaaactg ttgtccttgt catagatagt aaaggagagc ttgaaaatga aaactgcgat
    60841 tacgtttcta ttagaggaat atgccgattg ggaaggtgct tatattacta gcacactaaa
    60901 ccaaaaagag ggatggcaaa acaaaactgc ttctatccaa tcagaggtca cttccattgg
    60961 aggattaaaa acaaaaatcg attacttaat cgaacaaata cctgaaaaag ttgacctttt
    61021 tattatgatc ggtggcaatt catgggacat aaaaaatcat catttatatc aaataatcga
    61081 taaattgtta aaaacagacg taccagtagc tgctatttgt ggggcagttg attatttagc
    61141 tcagagcgga ttattgcaag gttacaaaca caccggaaat gcgcaatttc cttggttaga
    61201 atcggaaaat tatcagaata aagaagattt tatagaacaa caagctgtga aagatcgtaa
    61261 tttgattact gcgaatggaa cagctcctat agaattcaca gacttgattc ttcaagcagt
    61321 ccattttgaa acagaagaaa taagagaaaa aaagattcgt ctatacaaac ttggattcta
    61381 tgattactat aaaaagtacg gagatccttt ctcctaatca ttctcttcaa ttaaatactc
    61441 cttatcaata gtatgacaag taattttact gatggttatt tgtcacactt tttctgacat
    61501 ttatcaaaga agatacactc tatttatatt cata
//
LOCUS       DAXQKX010000011        59637 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.011, whole genome shotgun sequence.
ACCESSION   DAXQKX010000011 DAXQKX010000000
VERSION     DAXQKX010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59637
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.011"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(451..1761)
                     /locus_tag="ACF3MF_000745"
     CDS             complement(451..1761)
                     /locus_tag="ACF3MF_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004650 - polygalacturonase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 28 protein"
                     /protein_id="HFE3926766.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1773..3191)
                     /locus_tag="ACF3MF_000746"
     CDS             complement(1773..3191)
                     /locus_tag="ACF3MF_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFE3926767.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3431..4999)
                     /locus_tag="ACF3MF_000747"
     CDS             complement(3431..4999)
                     /locus_tag="ACF3MF_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HFE3926768.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(5003..5413)
                     /locus_tag="ACF3MF_000748"
     CDS             complement(5003..5413)
                     /locus_tag="ACF3MF_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HFE3926769.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5410..6333)
                     /locus_tag="ACF3MF_000749"
     CDS             complement(5410..6333)
                     /locus_tag="ACF3MF_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030599 - pectinesterase activity
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pectinesterase family protein"
                     /protein_id="HFE3926770.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6330..7208)
                     /locus_tag="ACF3MF_000750"
     CDS             complement(6330..7208)
                     /locus_tag="ACF3MF_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HFE3926771.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7195..8532)
                     /locus_tag="ACF3MF_000751"
     CDS             complement(7195..8532)
                     /locus_tag="ACF3MF_000751"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HFE3926772.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8535..9638)
                     /locus_tag="ACF3MF_000752"
     CDS             complement(8535..9638)
                     /locus_tag="ACF3MF_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFE3926773.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9712..11220)
                     /locus_tag="ACF3MF_000753"
     CDS             complement(9712..11220)
                     /locus_tag="ACF3MF_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFE3926774.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11186..11878)
                     /locus_tag="ACF3MF_000754"
     CDS             complement(11186..11878)
                     /locus_tag="ACF3MF_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HFE3926775.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11900..12874)
                     /locus_tag="ACF3MF_000755"
     CDS             complement(11900..12874)
                     /locus_tag="ACF3MF_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFE3926776.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13174..14046
                     /locus_tag="ACF3MF_000756"
     CDS             13174..14046
                     /locus_tag="ACF3MF_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFE3926777.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14504..16702)
                     /locus_tag="ACF3MF_000757"
     CDS             complement(14504..16702)
                     /locus_tag="ACF3MF_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3926778.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEIEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16934..17926
                     /locus_tag="ACF3MF_000758"
     CDS             16934..17926
                     /locus_tag="ACF3MF_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFE3926779.1"
                     /translation="MVTIKDVAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17986..19407
                     /locus_tag="ACF3MF_000759"
     CDS             17986..19407
                     /locus_tag="ACF3MF_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HFE3926780.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSLPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19400..20899
                     /locus_tag="ACF3MF_000760"
     CDS             19400..20899
                     /locus_tag="ACF3MF_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HFE3926781.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20938..22332
                     /gene="uxaC"
                     /locus_tag="ACF3MF_000761"
     CDS             20938..22332
                     /gene="uxaC"
                     /locus_tag="ACF3MF_000761"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HFE3926782.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22491..23174
                     /locus_tag="ACF3MF_000762"
     CDS             22491..23174
                     /locus_tag="ACF3MF_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HFE3926783.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            23176..24012
                     /locus_tag="ACF3MF_000763"
     CDS             23176..24012
                     /locus_tag="ACF3MF_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFE3926784.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            24023..25777
                     /locus_tag="ACF3MF_000764"
     CDS             24023..25777
                     /locus_tag="ACF3MF_000764"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3926785.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(26053..26394)
                     /locus_tag="ACF3MF_000765"
     CDS             complement(26053..26394)
                     /locus_tag="ACF3MF_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFE3926786.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26462..28633)
                     /locus_tag="ACF3MF_000766"
     CDS             complement(26462..28633)
                     /locus_tag="ACF3MF_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HFE3926787.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28844..29701
                     /locus_tag="ACF3MF_000767"
     CDS             28844..29701
                     /locus_tag="ACF3MF_000767"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFE3926788.1"
                     /translation="MKITITLPMNHPETTIRDLLEKEWLVPRKVRHFLRIRKNVWINQ
                     QPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDEHLIIVDKPAGMKTH
                     PNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKNPFVLPILGRMLEQK
                     MIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSALTHVTVNKVLSEQT
                     QVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHALELHMIHPFTQEKIV
                     GKALPGLWE"
     gene            complement(29772..30629)
                     /locus_tag="ACF3MF_000768"
     CDS             complement(29772..30629)
                     /locus_tag="ACF3MF_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFE3926789.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(30614..33316)
                     /locus_tag="ACF3MF_000769"
     CDS             complement(30614..33316)
                     /locus_tag="ACF3MF_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HFE3926790.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(33329..34618)
                     /locus_tag="ACF3MF_000770"
     CDS             complement(33329..34618)
                     /locus_tag="ACF3MF_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HFE3926791.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            34768..35814
                     /locus_tag="ACF3MF_000771"
     CDS             34768..35814
                     /locus_tag="ACF3MF_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFE3926792.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            35816..37969
                     /locus_tag="ACF3MF_000772"
     CDS             35816..37969
                     /locus_tag="ACF3MF_000772"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HFE3926793.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(38442..39893)
                     /locus_tag="ACF3MF_000773"
     CDS             complement(38442..39893)
                     /locus_tag="ACF3MF_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFE3926794.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(39890..41614)
                     /locus_tag="ACF3MF_000774"
     CDS             complement(39890..41614)
                     /locus_tag="ACF3MF_000774"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFE3926795.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            complement(41607..42221)
                     /locus_tag="ACF3MF_000775"
     CDS             complement(41607..42221)
                     /locus_tag="ACF3MF_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFE3926796.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            complement(42566..44023)
                     /locus_tag="ACF3MF_000776"
     CDS             complement(42566..44023)
                     /locus_tag="ACF3MF_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFE3926797.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            complement(44064..44984)
                     /locus_tag="ACF3MF_000777"
     CDS             complement(44064..44984)
                     /locus_tag="ACF3MF_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFE3926798.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            complement(44996..45943)
                     /locus_tag="ACF3MF_000778"
     CDS             complement(44996..45943)
                     /locus_tag="ACF3MF_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFE3926799.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            complement(46422..47141)
                     /locus_tag="ACF3MF_000779"
     CDS             complement(46422..47141)
                     /locus_tag="ACF3MF_000779"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFE3926800.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            complement(47190..48836)
                     /locus_tag="ACF3MF_000780"
     CDS             complement(47190..48836)
                     /locus_tag="ACF3MF_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis C-terminal
                     domain-containing protein"
                     /protein_id="HFE3926801.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            49015..49605
                     /locus_tag="ACF3MF_000781"
     CDS             49015..49605
                     /locus_tag="ACF3MF_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFE3926802.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            49697..51202
                     /locus_tag="ACF3MF_000782"
     CDS             49697..51202
                     /locus_tag="ACF3MF_000782"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HFE3926803.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(51286..52638)
                     /gene="celB"
                     /locus_tag="ACF3MF_000783"
     CDS             complement(51286..52638)
                     /gene="celB"
                     /locus_tag="ACF3MF_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFE3926804.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAISFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(52638..53156)
                     /locus_tag="ACF3MF_000784"
     CDS             complement(52638..53156)
                     /locus_tag="ACF3MF_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926805.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(53172..53498)
                     /locus_tag="ACF3MF_000785"
     CDS             complement(53172..53498)
                     /locus_tag="ACF3MF_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HFE3926806.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(53511..55490)
                     /locus_tag="ACF3MF_000786"
     CDS             complement(53511..55490)
                     /locus_tag="ACF3MF_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFE3926807.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(55511..55825)
                     /locus_tag="ACF3MF_000787"
     CDS             complement(55511..55825)
                     /locus_tag="ACF3MF_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HFE3926808.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            55993..56286
                     /locus_tag="ACF3MF_000788"
     CDS             55993..56286
                     /locus_tag="ACF3MF_000788"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="HFE3926809.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(56364..57476)
                     /locus_tag="ACF3MF_000789"
     CDS             complement(56364..57476)
                     /locus_tag="ACF3MF_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFE3926810.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            57629..58477
                     /locus_tag="ACF3MF_000790"
                     /pseudo
     CDS             57629..58477
                     /locus_tag="ACF3MF_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(58830..>59637)
                     /locus_tag="ACF3MF_000791"
     CDS             complement(58830..>59637)
                     /locus_tag="ACF3MF_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFE3926811.1"
                     /translation="GYELDATPIEFEIERSQTAVVELTKANRLTPGGVVLTKIDDQSG
                     EVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGVYQLVETQAPTGYELDATPI
                     EFEIERSQTAVVELTKENRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLT
                     TGADGKLAIDGLAPGAYQLVETQAPTGYELDATPVTFKIEKEQEVAIFLTKENRKVAD
                     SSDIRGNNPTSSGNKHLPKTGETIISQFILSILGVLLVFISIKFRKKRNI"
BASE COUNT        17826 a        12190 c        10425 g        19196 t
ORIGIN      
        1 ttgtcttgaa ttgaatcaag acgccctaca catttggttt gtcttacttt gttcagtttt
       61 caaaggtcta cttcatcgag agtgtttccc gattcatttt tggctgccgt agcaactttt
      121 atatcatatc agagagacaa acgattgtca actctttttt aaaagttttt ttcgatttcg
      181 tttttcgaaa tctttcagca actcatttat cataacttat cgtttgttat ttgtcaagaa
      241 cttttttgaa gtttttttcg atagaatcaa gcttcgcaag tggttctttt taacgactta
      301 gttatcttat cacgtctaaa aacatgtgtc aactcttttt tggaattttc ataaaatgtt
      361 tcaatgaagc gcgacaacgt tgtttaatat atcattaaaa aaaataaagg tcaagctaaa
      421 atattattta agcttgacct tattataatt tcaacgattg tcaaaagtat tgtttgcagc
      481 tgtgttgcca gtttctatag ataaatcaca gcttttgaaa cataagtttt gtactgcttc
      541 gattcgcccg aattcttttg cagttatttg gcaatgagaa aagcagacat cttctatagg
      601 cttttcagga aatgctacta aatcaaaagc tcgggaagga agtgagtaac ctggagaaag
      661 gcatgcctgt acgtttttga tgtgtatgtc tttgactttc gtcatttgct ttgattcagg
      721 tatttcttca gccactgctt gccaactttc tggcatttga gcaaggtcat tgctattttt
      781 tctattgtat tcattatgcc agtccattat ccaagaaaaa ggaaattgta catcaatcat
      841 attcagattt tctaccctga tattttcgat cactccccct ctttcttttg aagatttcat
      901 tcgaatacca cagtctgact gaaaaaaatc gatatcgtga atatatacgt cactaactcc
      961 agcactaact tcgctaccaa tagttacacc gtatcctgaa cggattttac atctagcaac
     1021 ctcgattctt gatgattttc gattgactct tgcaccattg ccatctctgc cagacttaat
     1081 agcaatacaa tcatcaccac aggccaaatc acattcatag acacgcacat ttgttgaaga
     1141 atcaatatca atcccatctg tacttggtcc atcattgttg cggatgatta ctttttctac
     1201 taatacatcg ttagaataag tgatttgcaa gttccaaaaa cctgatttct gaaaaatcaa
     1261 atcacgaaca acaacatgtt ctgcatgata cagtaaacaa gcgcgtggac gtttaatagc
     1321 ataatccgca atccaacgaa gtcccttttg atcgtattca gctcttgtcc cgcttttttg
     1381 atcttttccc caatacagct cccaccaatg gtctccttga ccgtcgatta ttccttttcc
     1441 ttctataaga atatctttcg ccgagagaac attcaaaatc gctgctggcc atttcatttc
     1501 tacgccggct actcgtgtat cgatttctgg aaatgcttcg atatctgttc tccccttgag
     1561 gactgcacct tcttcaaaga taagatgact cttatctttt aaaaaaaggg ctccgactaa
     1621 ataaatgcct tttggaataa atacaggtaa gtgttctttc gcaccttgat cgattgcttt
     1681 ttgcagtatt attgtatcat cttgttgagt gtcgtttgtt ttaaagttca aagcattgat
     1741 aatccctttt tttgtccgca atacgtttct ccctatcttt cattgatttt tttcaattct
     1801 tcaccaataa atacagtttt tgaacgattc agtgggtaac ctactagcaa aatgattgcg
     1861 gatacaaata agcagaatgc tggtaacaag tttgccatcg tataaatcct ttcttgtact
     1921 aaaactgatt ggatggctcc acctgttgta gacgattggt aaccaatgag tgccagcata
     1981 aatccgccta ccgctcctgc acatgcttgt cctacttttc tcgcaaaaga atttactcca
     2041 tatactgttc catcttctct taagcctgtc ttatattgat gataatcaat cacgtcagta
     2101 atgaatgccc agaccatcaa attgaataaa ccagatccta aagtagcgat aaataaaaga
     2161 atcagatata cccatgcatt tgttatatga aggaaataca tcagcaagta catacatgaa
     2221 gaagcaagta acgcaaatac gcttgcttcc tttttaccaa ataattttgt cagctttgta
     2281 gcaaatggtg ctaaaactac tactgttccg taagtaaata aaagagcaac agacattgct
     2341 tgtttattat ggaagtaatc attgaataaa taagtcatat tcgtcccagc taaaatctga
     2401 ttgatcacaa tgaaaatgtc aacaatgact aaaataatca gtgctcgatt agctaacaaa
     2461 ccttttacca actgagaagc agatactttt tcgtttttga caactcttac tctttcagta
     2521 gtcaatttac aagttaacat atatgcgaca aatgctattg cagcacatcc gattgaaatc
     2581 caaaagaaat gattccctga aacgacttgt tgtccactct tgttatgggt atacattaaa
     2641 atcggaatga agaatcctgt agttgatccg ccaatcgcag aaccaatgct tcggaacgtg
     2701 gacaacgagg tgcggtcatt aggatttgag ctaattgctg ctgccattgc tccatacggg
     2761 atattgattg ttgagagaaa aatcccataa acaatgtatg aaacaaaaat ataagcaatc
     2821 ttcaccgtca ttggaagatg ttggacgaat ggcaaaaaca aaatgacagt cactaagcaa
     2881 aatggatact tcatttttct gatccaagga ataaatcggc cagtttctgt taactctgag
     2941 acatcacata atcttccaac catcacatca gcaaacgcat ccaaaattct cgaaatcaag
     3001 aataacgtac ctacgattgc ccctgaaacg ccaagaacat tcgtataata aatcatcaag
     3061 aaactattga ctaaacctaa aataaaacag ttacctagat caccgaacat gtagcctatc
     3121 ttatcggaaa tcccaaattc ctttttttct ttttttattg tatttgctgt aacagcattt
     3181 tgtgaaagca tttgaattcc tcctacctct tctagtaaac gttttcaaaa ttataactct
     3241 ttttttcttg tttttatatt cacaatgttg gctttttatt gcattatctt gacagataaa
     3301 aaacaaaaaa taatctaaaa acattgatgc ataagattga taactttttt tacataacaa
     3361 tatatacaaa caaaaaaatt cactaactag tgaaaataag ttagtgaacc tcatttatta
     3421 aagaattaaa ttacagatga tcttttccat catacttgaa aaactcaaaa tcagcataac
     3481 ttcctctttt tttatttaga tcatgcactg ctatcccgat aaaatttcca gtaaaccctc
     3541 ctgagagtat acacatgttt ttttgcggac ctactttctt ccattcttca gttgatacgt
     3601 ctttcaaatg aaactgtgct gtctctttct ttacagtgac tttcaaaaaa gtcttctttt
     3661 ctgtgagtgg aatcgtccaa tcttctattt gtgctactcc gttttctgat tctatcatac
     3721 gtaggcattt tcccttgtcc tcattccaag taacataaca ataaatataa ttggattcat
     3781 ttaagtacag taccagtcca gccatctgat taaaattatt aggcatgtat tcaaatgctg
     3841 tctccgcatc aaaagtaaaa tccgtttgcc gaatagctaa caaatgatgt tcgaaggtag
     3901 attgaagaga ttcaccggaa atcagacgta aaaaacctgg tctacatttt gtatcacacc
     3961 aatcagcatt tggcaaaatg cgtctggcat tccagttctt ctttagctct ccttcaaatg
     4021 tatccataaa ctgatgatct ttttcttgtt gtacctcttc atttgtctca atcattattt
     4081 cttccatcgg agttgtctgg ctatctttaa gtcttaacca atcgtcggac gtccaataca
     4141 cttcttgaat agcggtttct cttcccaaaa tagccgcacc gtttaatggt ctggtacaaa
     4201 gatatgtcat gtaccatctt cctgacgggg tttgtactaa gctcccatgt cctgtacatt
     4261 gcaatgtaga agcaggtttg tcactagctg tcagcatagg aaaaccagga tcaagctcgt
     4321 aaggaccagt aatattcttt gctcggcaaa ctgtaactga atgtcctctt cctgtaccgc
     4381 cttctgccgt catcaaataa taatacccgt tacgaaaata caaatgtggt gcctccgttt
     4441 tcgctaattc tgtacctgca aatattttat agatgggacc atcaagcttc ttcttctctg
     4501 catcatattc ttgtaatacg ataccgctgg atttattcgg tgtgtccaga cgataatccc
     4561 atagttcatt gacaagccat ttttttcccg tttcaagatc atggaacaaa gaaggatcaa
     4621 agccgttact atttaaataa attggttcgg accaaggacc tgtgatctca gatgcagtga
     4681 tcaaataatt gtggacatct ttaaacggac ggcctgcact tttgacatct gtgtaaacaa
     4741 gataaaacaa tccatcagca taactgatct gtggcgccca tatacttcca tttgtaggat
     4801 ttccttgcaa agatacttga gtggtcaaaa tatccgttgt atgtgaccag ttgactaaat
     4861 ttttcgactc atatactcgg attcctggaa gccattcaaa agaggagaca ataatgtaat
     4921 accgctcttt cactcttaat atattaggat ctggattgaa tcctcttaaa ataggatttt
     4981 tcactttgat agtctgcatg attcaggctc cttttctcat tcttactcga tataaactga
     5041 atgccccagc tgcgaaataa aaaaatgcaa aaggaaacgc aataaactga gtgccaatca
     5101 acaatatgaa tcctgttata aaatacaaac cagtggcagt tgttaagtat tttcctttag
     5161 cagtcaaaaa caatgctact gctaaaaaag caagtgaaat aaacaacaca acggcaaaca
     5221 gaccagtcat gtcctgtaat aatccaaatg tattttctaa agacaaagtt gaatgatcta
     5281 cagcaagcga ctgataactt tttttaaact ctgacgcaga catattactt aaagtaactg
     5341 ctaacccgcc aaagaaaatc aaagatagac tgccaccgac cattcctagc aatagttccc
     5401 attttctttt catttctgaa ccccctgctt ttctaaatgt atccattcag gtcttttgat
     5461 cgatgtttca taattgttat tacgttcaga gaatttgaca gtctgttcat ttttcttgtc
     5521 atcccaatta tcccaaccag ttgggtgaac atgcccacct atcttacacg cttcaaataa
     5581 gacatttgca tacggacgcc acggtcttcc taaatagacg tttctagtat caggttctgc
     5641 agtcaaggta cagctttcaa aacgataccc tgttttttga tttttcggcg tagatgctgc
     5701 tgtgatgtat ccaggatttt tactggctaa gctatggata tgacactgat gaaaaacggc
     5761 atctgcccca ccaaatatga aatccaccgt tccttcaatc cagcaatatt cataggtctg
     5821 acgacaatac tcaggattgg cagaagccgg tgtacaaaaa ggagtaccat ctttttgcaa
     5881 atcaggcaac ggacccgtgc ataaggtatc ctgataacca gatagtcgac agttttttaa
     5941 agatacgcga tctcctgaat tgaataaagc aacagcctgt cctacctttt ctcctggacc
     6001 tgctgtattt tcgatgtgaa gattttctaa tacgacattc gatccttcta agaaaaaagt
     6061 agcacttcgg aaagtcccta actggctacc gtcaagatac tcctgttttg caaaacgatt
     6121 accggagata actactgttc ctgctcccac aagtttaaaa ttggataatc tgctttctat
     6181 atattcatca tatcttcctt cttttactat caagaccttt ggatggctat ccggcaggcc
     6241 tgccaaataa tcgattcctt cttggatagt ttcaaaatcc gtcggggtat ctatagcatt
     6301 ctttccaatt atcagtttgt ctttcatcct cataaatgct cccttatgaa ttgtttccaa
     6361 atatttctca tttcttgtgt ttccatatga ccgcctgtta aagaaaaaga agaaaagttt
     6421 tctggactac ccattgattg atactttttg tccagccctt ttctcagctt cagtacgcct
     6481 tcgtccaagc acatcgtatc gttttttcca actaagctaa gacgagggcg cggagcgatt
     6541 ttttcttgga ttgctaacgt tgtataagct gtcaatagat ttggcacata gtaataaaac
     6601 ccatgatgat ctaggcggcg atgtagcaaa agtatttcga tgtccacctg tgccgctaga
     6661 tcaatacaaa ctttgacacg agaatccaat gctgtcaccc accagcttaa taagcctccc
     6721 atagaaagac caatcgttgc gagccgttga gtatctgtgt cttcccttgt ctccaaataa
     6781 tcgatcaagc tgatcacatc ataaatacgc attccccata acgtttttcc tgttaataaa
     6841 aattgtttga acaactcgct ttcagaaata cctccgcgtt cttcaaatcc ccaagcatca
     6901 atcgaccaaa cagcatatcc cattcctgtc agtacttctg caaaagatgg agaagctaag
     6961 taaggagcac catggatcaa ttcacttttc ccgactgaaa aatctccgcc gtgagaatgc
     7021 aggtaaagga ccggcggaaa cggtccttct ttttctggat aagcatagag ggctggtact
     7081 gtttccaatt catttaagta caattgatag tattcaagca taaaaccgtt ttgtttttct
     7141 cggtataatc gttttccact aggggtatgt ctgctagatg gagcacctaa aaaatcattc
     7201 aactgcataa gcaaagtttt tacgaacaac cagttcatcc atattttctg attgatttga
     7261 ttggaatttc tcaatactga tttctttagt attttctaat agaaatgctg gtccctcgtg
     7321 attttcaatc gacatctggt taaaggaaac cttacccgca aagccaatat aaaatccttg
     7381 tctgctcatt tcctctattc ctgtcatcat agcaggaaca ccgggaactg catcttgggc
     7441 catcgagaca tcgatattgt caaatgtgat ttcttgtatg aattgttccg ctaatccata
     7501 aataaaacct gcagaagcat ggacattcct tgccgtgata ttcgaaaaat ggatccttct
     7561 gaatgctggt gtccgttcat ctatcggata agcctttttt tcccatacat acggttcttt
     7621 ccctcgcgga ccacagaaat aataaagatt cagtataaat ggacacatca cattatccat
     7681 gactatattg gatactcgaa tatcttcaac gatcccgcct cgacctcgtc tagatttcaa
     7741 tcgtattcct cgatcagttt cttggaagat acaatttgaa atggtaatat tacgaatact
     7801 accactcatt tcacttccta atacgacacc gccatgtcca tggaccatcg tgcaatttgt
     7861 gatcgtgata ttttcgcaag cgatcctttc gtacgtatct tcagtccctg ccttgattgc
     7921 aatacagtca tctcccacgt caatatggca attactaata cgcacatttt tgcatgattc
     7981 tggatcaatt ccgtctgtat ttggtgaatc cgctgggttc aagatcgtca agttatcaaa
     8041 cgttgcatta ctgcaaagaa tcgggttgat cgtccaactt ggtgactgga tcaatttaat
     8101 atctttcaca gtaattcgat gacagttatg gaaactcatc aatttaggac gaggataagc
     8161 gagattatct ggttcatttc taaaagtatg ccaccatttt tttccatttc catctaatgt
     8221 accgaaacca gtgacagaga tgttctctac attttgagca tagatacagg aagcataaac
     8281 ttttcgatgg actccttccc aacgtgaatg aacaacagga taatcttttg gatcgtcaga
     8341 gaatttcaga accgctcctg cgcttaaatg aagttcgaca ttgcttttta aaaataaagc
     8401 tcctgttaga aattcacctg ctggaacaac tacggtcccg cctccgtcac ttgctgcagc
     8461 atcaatggct tgttgtattg cttcagtatt caattcatca attgatgcgc caaatgtcaa
     8521 aatatcatac atatttataa tgcctccact tcaatcaatg cttgcaagaa tgcaccaacg
     8581 cctttttgat cattacaaat aattggttca ctgatgtagt aagcatatga accatctcgc
     8641 tgatctgctc cgcctaaccc tgctacttga cagtttttat tcaagttcag ccagccttct
     8701 tttgtttcca gaacaaattc atcaagtaat ccttgatgtg atttcttcac ttgtggaagc
     8761 cattcttctt tgttcagcag tcccaaacgt attcctttag ccattgcgta aacaaacata
     8821 ctactgccgg aagcttccag ataatttcct ttccgttttg tttctgttgt tacttgatac
     8881 catgtcccgc tgttttcttc ttgatatgga agtaatgcag ccagtgtctt ttctagaatt
     8941 tctttcagca aagaacaatc tgtttcttca tgaagtaatt cataggtatc tgctgcagcc
     9001 atcaaatacc agccaatcga tcggctccaa aaatgatggg atagacctgt ttttggatca
     9061 gcccatggtt ggaccttctt ttcatcccat gcatgaatca gcaaatttgt ttttggatcg
     9121 aatagatgtt tataactgat ttcaaactgt ctcaaaacat cttggtaatc tttttcttca
     9181 ctaaaattct ggataaattc agcataaaaa ggagaaccca tatataagcc atccaaccaa
     9241 atttgataag gataaatttc tttatgccaa aaagctcctt cggatgtgcg tggatggttt
     9301 gccaactgct gggaaaggag ttctgctgct tttttatatt tttcttcgcc tgtttctttg
     9361 tacaataaaa agaaaagctt tcctgtattt acatggtcga tattgtattc ttcaacgctg
     9421 tagccacgga tcgttccatc ttcttgcacg aaatagtcga tattgtcttt tatgaaatca
     9481 aaataaattt tttcttgggt tcgttcccaa agtaattgga accctttaag tacgacgcca
     9541 tagtcataag accattttcc tttataccac ttttcttcat ataagcgagg tgttctttcc
     9601 atgatacttt ttgctaattt ctttgaccag ttttccatta tttgctctcc tttaaaaatt
     9661 aaaataggat ttgggacaaa taccaagaag tatttgtccc aatcgtctat attactgtgc
     9721 cgctgctttg tatgcttcct cgtactcttg tgtgattcga tcgcctcctt gtgctttcca
     9781 gtcttctaca gcttttttga atccatcttc gtcaagctgt cccatgatgt attgcaccgt
     9841 agcatcaatg acgatttttt caatttctga tcctacttca ttgttcgtcg gtgaatccaa
     9901 tggcacagaa ggatccatta cagcaaattc ttcattttct ttgatcaatt gattagagaa
     9961 ttctttttca gggtctgtat ctttgaaaga gaacgtcact tcactaggac gagagcttga
    10021 taacggttgc acctcttgtt gccaaagatc catatcgata aattcgatag aaccatcatc
    10081 attcaattca taatgcgttc cttcgatacc gccagtcatc aatttataca catcttcttc
    10141 taaaagatca tcaacaaatt gaagtaattt cttcaattgt gcttcgtctt ttacttgaga
    10201 tttgggaaat gctagcaagc cgccaatacc atttccttct gaccaaacat gataaccgcc
    10261 gccttcacca tctgagatct tgtttacagg cactaattcc atatcatctt gaataccttg
    10321 acccatcgtc ttcagattct tgatatccac cattccagtg tagattccag ttcttccttg
    10381 tgcaaattgt tcttgctgat cagtcttttg ggtaactgca aagtcttgtg ccaaatagcc
    10441 attctcaaat agatctcttg aaaaattcaa agctttcata tactcttctg tatcaaattc
    10501 tggagtgaat ttgccattat cgtctacagc ccagccattt ggtgctccaa aataagaagt
    10561 gaaaagttta aagctggtat aacgaatatc actaggcgca cgatcgccaa aaccaactgt
    10621 gtcgtccaca ccatttccat caggatcgtt ttctgtaaat tgtttagcta cttcataaag
    10681 ctcatccatg gtagttggaa catctagtcc tagattatcc aaccagtctt ttcgaatgac
    10741 taagccagca cgagcgtagt ctttttgtat cggtacgccg tacaaggcac cgtcgatact
    10801 cgcagcttcg attctatctt cagaaatttg acttaaattt ttatagtctt ttaaatattc
    10861 tgatacatcc cagaatacgc ctgattttaa cgcattgcgg acagaagagt ttttcaacat
    10921 cgcaatttga agtgtaacga tatctcctag ttcatcagaa gccaatgcag ttgttaatct
    10981 ttcttctttt gaagcatcag gaatccagtt gaatgtcagt tccgtatcgg ttttttcttc
    11041 gatcaagttc acaatcgtgt ctgtaggcgg tgaagcatga tgcaaaatat ttaaccaagt
    11101 gattttagct tttccatctt ctgtctctga agaactgtta cttgaactgc tgccgcatgc
    11161 ggcaagtgct agaattcctg caaaactaag acctaatttt acgagcgttg cttttttcat
    11221 aaattttctc cttcactgtt ttaataatat ttttgttttc ttctgttttt tctgtatatg
    11281 agttcttcca ttccaaatgg caaaatatag aatttgctgt ccacgtgact gcggaaaaga
    11341 agagactgcc accgataaag gttaaaacac ctggcattgt ttggatgatc atcagataaa
    11401 tccctaccat acttaatatc aacactaatg agtaatgaag atgtgagaat ccgaataaaa
    11461 atgccatttt cattttgaaa aaatatcctt tccaatcata atgagccatg attgggaaaa
    11521 tatagagtgc tgagagcaca tatatgaacg cagcaatata caaagcgatc ctaagatacc
    11581 aattgtgtat gaaagaaaga tccacaagta aaacaatccc gatggcgcca tatatccagc
    11641 tcatcagcaa ggtttcacga tagttttctt taaaatatgt gaagtacgtt ttcgtcaaag
    11701 gaaacgtttc ttttgagcgc agccattttc taatcactgc aaccatcgca tacgatgcag
    11761 gaccgaaagt aaaaactccc aaacctgcga tgactaaacc gccccacaga aaattcaaat
    11821 aaaccaactg taaaatacga tttagccttc cgtttatttt atctaatgac tgcagcatat
    11881 ctttccctct ctttctatct tagtaaacgc cgtcttctcc tagctttttg gcaatcttat
    11941 tagctaaaat taccataaac aatcctacga cccctttaaa caatcccatt gctgtactga
    12001 aacttaactg tccattcttc aatccagctg tataaatata ggtgtcgaaa atttctgcaa
    12061 cgcttcgatt caatgaattc aataacaagt acatatgctc gaaccctaag tctaatgtct
    12121 gaccgatttt tagaatcagc aaggtaatga ttactggacg aattgccggc aatgtaacat
    12181 gccatgtttt gcgtaagcgt cctgctccat ccatttctgc agcttcatac aactgtgtat
    12241 cgactgcagt tatcgctgaa aggtagatga tcgtagacca gcccaactct ttccagatca
    12301 cttgtccgat atatactgtg cgtgtccatt caggggatgt tagaaaactg attttttcaa
    12361 atcccattgt tgcaaggaat tcattcaata cccctccgtc aacattcaaa aatacataag
    12421 taatcgaaac aatgattacc caagacatga agtgagggat gtaaatgatc gtttgaatcc
    12481 cgtttttcaa tcgtttgttc gttacttcat ttaatagtaa agacaaaatg attggcatcg
    12541 gaaaaaacac gaagatattt aatccgaaca agatcaacgt atttcttaat aatgtaaaga
    12601 atgtcggttc tgtaaacaaa cgaatgaaat gtttgaaacc gacccaagga cttcccatta
    12661 ttcctaaaaa tggttgataa tcttgaaaag caataacgag tccccccata ggaagatacc
    12721 taaaaatcaa gaaataaagg actcccggca gaatcatcac atataaaaat ttattcgttt
    12781 tgattcctgc aattattttt tttcgtcttc tgagcttttc ttcttttttc gatagcgtca
    12841 gttgaaatgg ttcttgtttc tttacacttt ccataagccc ctccttagtt ttgtgaatgt
    12901 ttgctgctta tgacttcatg atagataact atctgaatta cgtatataat catttttacc
    12961 gtaagtaaaa acgcttacat agcaatgatt tttgtgctat acaaaacgat aaagtgtatt
    13021 ttttcacaaa taaactacgc atagcaaacc ttctattttt ttctatctga cacttagcat
    13081 aggaaatgat tatatacgta atctttcacc gatgataaat tgaacatata gaaacagaaa
    13141 catttaattt attttgagga ggagcctatc tatatgaaaa agaaagtctc tataggagaa
    13201 agaagtttta cacttttcaa caatacgttt ctaattttgc tagctttgat ctgtatcgtt
    13261 ccttttttaa atatcatcgc tacatctttt gcttctacac aagaagtcgt cgcgaaaaag
    13321 tttatccttt ttcctactac cttttcttta gacgcgtatc gctacattct ttctacgccg
    13381 accattttta gagcacttgc tgtttcgatt ggtgttacag gtgtcggaac gatcgtcagt
    13441 atgtgtgcaa cttcactgat ggcctacggt ctttccagaa agtatttgtt tggtcgaggt
    13501 ttcgtcaact ttcttgttgt attttctatg ttgttcagcg gggggatgat tccaacgttc
    13561 ttagttgttc gttctctagg gctggtcaat tcttactggg ccatgatcct gcctgtggct
    13621 gttaatgcaa tgaatatgat cattatgaga aactttttcc aagccttgcc ggatagtttg
    13681 gaagaatcag caaaaatgga tggttgcaca gattttggtg tatttttcaa aattatgctg
    13741 ccattagcgt taccgtctat tgctactatc tcgctttttt atgctgttac ttactggaac
    13801 acttatatga ctgctatttt gtatatcaac gattcatcta aatggccgat acagattctt
    13861 ttacgccaaa tcgtcattgt atcaagtggg atgcaagcag aaagtagtgc cgttgatgtg
    13921 attccaccag cacaaacagt taaaatggct gttatcgtta ttgcaacagt gcctatgctg
    13981 attgtttatc cttttgttca gaaatatttt gtcaaaggag cactcgtagg ttctgtcaaa
    14041 gggtgattat gtactgaacg caaaatggta gttgtgtcag aagtggtcag cttcaagaaa
    14101 taagaaggca tttacgaaaa ttgcttctta aatttttgtg aaatttcggc ttatttttcg
    14161 aagaatctac tcctggaaca ccgtgtatca gaggttgtga aagagacgtt cagccttgag
    14221 cgatgataaa aactctcaca aacattgcga cgagtaaccc acaggagcaa taagaagcga
    14281 ttttgaaaaa tagcttccca tatttcacaa aattatgcct tattgtcgat agcctgtctc
    14341 ttgaacgcca tttattcgta aaaaagaact gtgacaagac ttttgtcaca gttctttttg
    14401 cgtgcttagc cttgaaattt aactatccat aaatacaaat actagggtta ttctaacttc
    14461 ttttattgct tgaatcagtc cacaagaaaa acagcctctt gattcacaaa tatttttttc
    14521 gatattctcc cggcgtaatc gattccttct ttttaaagaa acgaataaaa ttttgcggat
    14581 ttcgatattg caatctttct gcaatctctt ttacggagag gttagtctct ttcaaccatt
    14641 tttttgctac ctctaaacga tgattttgaa caaaatcacc aaatttttct cctgtttcct
    14701 ttttaaatac attacttaaa tagttagggt tataatgcaa cctatcagcg atcacatcta
    14761 aagacagatc acgatcatat tctgtgtaga cgatatgcat aatattctcc gacaaatttt
    14821 taaattcatg atcagtgatt gcttgagagc attctgtgat tggcagaact aattgttcta
    14881 aaacaagttt ttctagttct ttgggatgat aattgttcag tgcttttaca taaatttgtt
    14941 tcatgttatc aaagtttttt gaatctactc ccaataactg tcctaattga acgagttcat
    15001 tgatcaagcg gaccgaaact acttcccgac tcaaaggatt tttattttgt gcaaacaatg
    15061 catcaatcaa ttcatgtact aaattcttca cttcctgatt tccagaacga atggcttcaa
    15121 acaatcgatt ttgttcttct atcggatatc taataagtgt tttttcatga gcagcaggaa
    15181 cgatttcctg ataaaaaata attgaacttg gaccagtatt tacacgataa tacagggctt
    15241 cttttgcccg atcaaccgat tgcttgcttt cattcagcgt ttcgaaccgg ttactgatgc
    15301 ctatactgat agttaaattc aagtattctt ttacacgttt ttgaatgagt cggcaatact
    15361 ccatgacttt tttgcttgct tctgcatcat ctttatccat tcgataaata gtggcttgca
    15421 tttcttcatt caaaacgatc ggcagcattc gattttcctt tggcacaatt tccgtgatca
    15481 tgttgttgat cgctaaaagt agcaaatcac gctccccacc gtgactatct tctaacagat
    15541 cgatttgaac caaagctgta taatagcagt cattttgaga actataacca aattgctgca
    15601 accgctgatc tagttctcgc ctttctactc gatttctaaa taaactaagt acaaatagcg
    15661 tttccagctg tggcttttgg gtaactaagt gtgcacttaa cgcttctttt tctcctatga
    15721 tccgactgac tgattgagcg accaaatcta gttctttccc actgaatcct tttgatttaa
    15781 gattcagacg ttcctgtatt tgagaaatcg gacgggcaaa tctgtccgaa aataagtagg
    15841 aaagaagacc aatgagtcct accagtgtta aagacactgc aactagcccg attctcagat
    15901 tgcggatcat tgcgccaatt gcactagagt caacttctaa tctgtaaatc caattattat
    15961 aatctgattt cagtactata tacgttttat ctttttctct tatcactttc agctgattgt
    16021 aatctagatc cacgtccgtt aatacagttg gttgctcttt attttttact gtctgagtag
    16081 taaaaaggtt gccaacttcg ttttcaatag aaagtatgtc ttctccactt tcaccaacaa
    16141 cttgttctat tgtatgtttc tctatcgtag caattcccaa tgcatatttt tctttttcaa
    16201 acattggcaa agaaatcacc atttcgattc ctttgttttt cttttgccaa aataaattat
    16261 ttttgttatt tatgtacttc tgttgatact tttcaatttc ctcttcggtc agttgactca
    16321 acgatccatt gattactccc catttaccag ccaaactgac taaatcataa ttattatcat
    16381 ccataacaat cgtttctata aaatttagtt ctttcctgat ttcagaataa gtggagtaat
    16441 ctgtatatgt cagcggatgc ttgaatatgt ccgagaaatt tttggtcgaa ccatacgtag
    16501 aaaacgaata ttcaatcgtt ctaattttcc attcaacgtt agttttaact tgcctgagca
    16561 aattcttttt gtctgttaaa taactcgatt cgatcgattc ataggtattc tggtaaatga
    16621 ataaactaaa tcctatgaca agtacggctc ctaataaaaa catcggtaaa aatattttat
    16681 aaaatactgt acttttcttc attttcttcc tctcctcctt ttaaaataaa aggctttcat
    16741 ttttctgtaa aattgatact catctaatta aatgagcatt ccccgctttc aagaatagca
    16801 taattaaaaa taaaaatcca agtaattttt aacgtgtgca atcttttcat atcaaagatc
    16861 tattgactta tcgtagttat cgtaatatga tgaatgcgtt aacaaaaagt gaaaaagtaa
    16921 ggaaaatgat ggaatggtaa cgatcaaaga tgtcgctaaa gcagctggcg tttctcatac
    16981 gacagtttct cgtgctttga ataacagcag tttaataaaa aatgaaacaa aacaaaaaat
    17041 acgacaacta gctaaggaaa tgaattattc gccaaactat agtgcaaaag gtttagtgaa
    17101 tcaaaaaaaa tatctaatcg gactattttt ctcaagtttg cataaaggaa cttcatcaaa
    17161 tttcctagca gattccattg caggcatcca ttcagtatta gacacaaatt acagtttatc
    17221 tgttgaaagt atcgatgttg ttgatttaac agaaatcaac ctgcaacgct acgatggact
    17281 gatcgttatg agtcaaagtg atgatgatca gcctttcatc gactatctca aagaaaaaga
    17341 atttcctttc gttgttgtca atcgtcacat caatgatcca gcggttatca acgtcactgc
    17401 cgatgatgcg gccggtgtta tgcaggcagt agattacggt attggatgcg gacatacgaa
    17461 gatcgcttat attggcggaa agaaaaattt tcgttcgaca aaagaacggg aaaaaggggt
    17521 attgaaaagt ctaaaaaaag cgagcatccc tgtcaatcca gcctattttt taacaggaga
    17581 ttacagctta gaaagcggcc tccaaaacat ggaataccta ttatcacttt ctgacctgcc
    17641 tactctggtt ttttgcggca acgacgacat agcgattggt gcattgagag ctgtacattt
    17701 agctggcctc cgtgttcccc agaacatttc tctgatcggg ttcgatgatt ctccagtcgt
    17761 ctcctatctc aatccgccgc ttaccaccgt acgtaagcct ttgaaagaaa tgtgtcaaga
    17821 aggaacaaag cttttactag atttgatcga aggcaggacg atcgaacaat ctaaaattga
    17881 gctctccacc ttgttgatcc ttcgtgagtc gatcaattac ttgtaaacta caagtaattt
    17941 tatataaaaa tgttaacgtg tgcataacac agaaaggaag tttatatgaa aaaactgaca
    18001 aaagaattag tgaaaaaaaa cgaagcacct gtaaaagttc ttcagtttgg tgaaggcaat
    18061 tttatgcgtg gatttattga ttggcagatt cagcagctga ataaccaaca attgtttaaa
    18121 ggtaatgttg caatcattca acctttagaa caaggtcttg gaaatatgat gaaccagcaa
    18181 gataatttat atacggtcat tttacaagga ctcagcaatg gcgaaatcgt tgatacttcc
    18241 gagattatca ccgtagtaga acaaatgatc aatccttatg atgaatggga tgcttatcta
    18301 tctctagcag aaaatgacga cttggcctat atcgtctcca atacaacaga ggcaggaatc
    18361 caattcgtgg agactgataa tttaacagat actcccccac agagcctccc gggcaaactg
    18421 acagcctttt tataccgacg tttcaaatta aacaaagctg gctttaccat cattccttgc
    18481 gaactgattg acagaaacgg cgaacgtcta aaagaaatca ttttacgcta cgcagaaaaa
    18541 tgggatttag aacctgcttt tgttgagtgg ttagaaaaag aaaatgtttt ctgttgtagt
    18601 ttagttgatc gcatcgtccc aggttatcct cgcgaagatg caggtgtttt caatcaacgg
    18661 cataactatg aagatcaatt gatggtcaaa gcagaaccat tcatgctttg ggtgatcgaa
    18721 gggcctaaag aattggagaa tcaactacca ttcaaacagg ctggcttgaa tgtcatcatc
    18781 acagatgata tgactcctta tcgtgaacgt aaggtgcatt tgcttaatgg accgcataca
    18841 gcgatggtcc ctcttgcttt gttggcggaa ttggaaactg tagaagaagt aatgaaagat
    18901 cctttattct ccgcatatgt tgatcagtta ttcaatctag aattgattcc tatgctttct
    18961 ttacctaaag atgaattagc catttatgct gaccaaatca aagaacgttt cttgaatcct
    19021 tttgcccatc acaaattaga agcgatttca ttaaatagtg tttcaaagtt cagcacccgt
    19081 ctgcttccag tgttcaagaa gtatatcgaa gaacaaaatc aggtaccacc gttaatcact
    19141 gtttcactag ctgcgctact tcttatgtat cgaggcgatc aagtaaagcc acatgatgat
    19201 gaaaagacga taagcgaatt tactgatgct tggtctgata atggaacagc tattcctcga
    19261 ttattgcaaa acgctgcgct ttggggagaa gatttgtctc aaataccgaa tgtgacagat
    19321 acagttcaag aaatagctgc aaagatcgat caaaaaggtg tccggtcagt attacaagaa
    19381 atgaaaggaa cgatggtcca tgcttgaaac cctgcaacca acaatgaaat taaatcgacg
    19441 agacagtgtg gtcgtcgcat taacccctat tccaaaacaa acacaactga cgattgatca
    19501 gcaaacgatc accactcttg aagatatccc gcaaggtcat aagattgcat tgggtgattt
    19561 gaaagctgga gacaacgtga tcaaatatgg ctatccaatc ggtcatgtga cgacagacgt
    19621 aactgccggt caatggctgc acactcataa tgtaaaaacc aatctttctg gtgaattgga
    19681 ttatcgatat gaaaaagatg tccatccaag tcattacctt tttgagaacc gaacatttca
    19741 aggttacttg cgaaaaaatg gaaaagtagg gattcgtaat gatttgtttt tagtacctac
    19801 cgttgggtgt gtgaatggca ttgctgaact gatcgtcaaa cagttcaagg aaaaacatcc
    19861 agatctggga cagtttgacc atattacgat tttaaagcat ccttatggct gttcgcagct
    19921 tggaaaagat catcaaaata ctcgagaaat tttagcggac gcagtaaatc atcccaatgc
    19981 cggaggagtt ttagtatttg gattaggttg tgagaacaat acagttcctg aattcaaaaa
    20041 aattttaggt gaatatgatg aagaacgagt gaaatttcta gtggctcaag atgtttacga
    20101 tgagatcgaa caaggtgtgg ctctattaga agagctttta acagcggcgg aaaatgacca
    20161 gcgcatatca gtcccgctct ctaagttgaa tgtcggtttg aaatgcggcg gttctgatgg
    20221 tctatcggga ataactgcta atcctttact tggtgcattt tctgactact tgattgctca
    20281 aggaggcagc acgatcttaa cagaagtgcc agaaatgttt ggcgcagaac aagtattgat
    20341 ggcacgagcg gaaaatgaag aagtttttga ctcaatcgtt gacttgatca atgacttcaa
    20401 acagtatttc ttgtcttacg gggaaccagt ttacgaaaac ccatctcctg gtaataaagc
    20461 aggtgggatc actacattag aagataagtc tttaggctgc acgcaaaaat caggaagctc
    20521 tcctgtcgtt gatgtgctac aatatggcga aaaaatcaga aaaccagggc ttagtttatt
    20581 gcaagctccc gggaatgatc ttgtagctgc ctctgctctt gcttcatccg attgccagtt
    20641 ggtcttgttt accacaggaa gagggactcc gtttggctca tatgtcccaa cggtcaaggt
    20701 atctacgaat acaactcttt ttgaacgcaa aggtcattgg atggatttta atgcaggcgt
    20761 cttattagaa caaccaatgg aagtaatctt agaatcgttt gttcaaaaaa tcatcgctgt
    20821 agctagtgga gaagaaacga aaaatgaaca aaatgacgtt cgagaaattg ccatttttaa
    20881 aaacggagta acactttgat tttcataaaa cagtataaaa agaaagaagg aagatttatg
    20941 tttttatctg atgatttttt attaaaagac gattgggcga aaaagcttta ccattcctac
    21001 gcaaaaaaca tgcccattat tgattatcac tgtcacttag atccaaaaga aatttacgaa
    21061 aacaacaatt tcagcaatct gacagaagct tggttaggag gcgatcatta caaatggcgc
    21121 ttgatgcgag cttgcggcgt gcctgaagaa aaaatcacag gaaatgcttc tgattttgaa
    21181 aaatttttag cttggtgtca aaccgtacca aaaattatcg gaaatccgct ttacagttgg
    21241 tcacatcttg aattgaagcg tttcttcggt attgacttgt tgataaatga agaaaatgca
    21301 gagaaaattt ggacacaagc aaatgaaatt ttggcagctc ctgattttcg ccgtcgggaa
    21361 atcgcaaaaa aatcgaatgt agaagtgatt tgtacaacag atgatcccgc agacgacttg
    21421 cactatcatc agttgcttgc tcatgaagaa ccagatttga aggttctacc ttcattccgt
    21481 ccagataaag cactcaatat tgaaaaagaa ggatttaatg catgggtcac actactggaa
    21541 gaagcagctg accaaacgat caccacctat caagaactga tagaagtctt agggcagcgg
    21601 atagaatact tccatcaaca tggatgtcgt gtttccgacc acgctttaga catcttacgc
    21661 tataaagaag cggatgaaac agtattagaa gagatttttc aaaaagcacg agctaacaaa
    21721 ctattatctt cagatgaaat cgatgcttat cgtacagaaa cactgataca tttgacccac
    21781 ttctatcatt ctcataattg gacgatgcag ctgcacatcc atgcttatcg taactgtaat
    21841 acacaaatgt tggaaaaatt agggcccgat accggctatg atggaatgaa tgatctttct
    21901 ttgactattc ctctgcaaaa attattgaac cgtgcagaag aaacggatca gttgccaaag
    21961 acgatccttt attcattgaa tccgaatgac tatcctgcga ttttagcttt gatgggctgt
    22021 ttccaaaaag aacagaatgg aaaactgcag ttaggttctg gatggtggta caacgatact
    22081 cgagctggta tgcgcgatca attgacacaa tttgctgatg gtagtgcttt ggggaatttt
    22141 gtcggcatgc tgacagattc aagaagtttc ctgtcctaca ctagacatga atatttccgt
    22201 cgtgttcttt gtgaattttt aggcgaaatg gtcatgcgag gagaagcacc tgaagatgaa
    22261 caacttttag gaagtctagt tcaagcgatt agttatacaa atgctaaaaa ttactttggc
    22321 ttttttgcct aattgattaa tagtaacagt aacgaatcaa aaacaggata gtgaaataac
    22381 ggaatccgtt tatccacgtt ttagagaaga agacggacca aatttgctcc gtcttcttct
    22441 cttgctgttc tgcttcattg cctataaacc tttatgaaag aagagataac atgcctacta
    22501 tccatattgc cggtgattct actgcggcag aaaaagatga aaacaagcgt cccgagacag
    22561 gttggggaga aaaaatctct gcttattttt cacccgagat ccagatcaat aaccaagcaa
    22621 agaatggacg cagcaccaaa tcatttatcc aggaaggaag gttagcccgt ctagcttcac
    22681 agtttcagcc gaatgatttc ttatttgtac aatttggaca taacgaccag aaaatccaag
    22741 aagaaagagg tacgcttccc ttcggtagct atttaaaaaa tctgcagata ttttttgaat
    22801 gcgcaaaaaa agcgaacgtc caaatggtct tactgacatc tgtgacgcga cgagattact
    22861 tagaaaacgg aacattgaat ccagatatac ttggagacta tccaaaagcg atgcgtgcat
    22921 ttgctgagaa acaccatatt cctcttttag atgtgttctc aagatcacaa gaattgttcc
    22981 agaccttctc aaaagaagag acaaaaaaat tctacctgca tcttatacct gatacttgta
    23041 aaaattaccc agaaggacta aaagacaata cccactttag tccagaaggc gctgataaag
    23101 ttgcccgaat aattgttgaa ttgataaaag aatcccgtct gcctcttgct aattatttac
    23161 aaaaaggagt ttgagatgtt tccattaaat ttaggcatcc gtgcccacga tttagatgtt
    23221 cgaaatcgtg aagaaatcgt tcaaaaagta tcacagcttc acttgtccca tatccaattt
    23281 gcaccacaaa aagcatttcc tgaacaactt aaattaactg acatgacact tgggagtgct
    23341 gcctattttg gtgaatactt ccaaaaaaac aatatcgaac tttccatttt aggatgctat
    23401 atcaacctat ccagcaaaaa tcaagaagtt cgtgcacaag cattggcaac tttcaaacag
    23461 caaattgctc tgtgctctgc ctatcaagcc aagatgattg ctacggaaac cggtagtgtc
    23521 tctgtcggtt acacaaaaga aaattttact gaagaagctt atcagatcgc cagaaattct
    23581 atcattgaat tagtcgctca tgcagaaaat tttggcgtaa ctgttgctgt tgaagcaggg
    23641 atcaatcatc caatctataa ctatcagtta gctaaacgtt taatcgatga agtagcttca
    23701 ccaaatttaa aaatcatttt agattgtgcg aatttgatgc ataaagaaaa tcatgctgat
    23761 caggaaaaag tgatccgagg tgccttggac aatttacatg gttatattac agcgcttcat
    23821 ctcaaagact atatcatgga aaatggaaag atccgcatgg tacctgttgg caagggctgt
    23881 ttagatttcc gcccggtact gcattatatc aaatatgagc gtcctctaat gtacgccact
    23941 cttgaagcta ctcctgagat ttatgttcct gaagcaatag aacacttgca gtttatttac
    24001 caagattgtt aaggagaaga ttatggagga acgaatacag aaaagttatc aaaaatatca
    24061 tgcaaatgct tttcagacat tgctgcatct ttatcaggga aattattggc gttttgccat
    24121 gtcaggactc ttttttatta tcaaacatct tccatcttgg ttaatgccga tcgctattgc
    24181 caatgtaatc aatgcagctt catcgaaaga ttcttctcag ttgcaggcca tttatttcaa
    24241 cgcttttttg atggcttgtc tgattggtca aaatatattg acgaattatt ttcatgtaaa
    24301 ataccatagc acttcgatcc gtcaagtaga agctggacta agagcgaccc ttatcaagaa
    24361 aatccaagaa ctatctattc cttatcaaaa agaattgcaa tctggacgaa tccagtcaaa
    24421 gatcatccgt gatgtagaag ctatccaaac gttgtcctct caagtatttg tcagcggatt
    24481 aaatatcgct gtcaatttat tcgtagcttt aggtatcacg ctttataaaa gtcctgttgt
    24541 tttcatgttt ttcttattga ctgttcctct cgccgcattc gttactctct ttttccgtaa
    24601 aaggatcaga cagtccaact cagacttcag gcaagaaatg gaagagactt ctgcaaaagt
    24661 gatcgaagtg atcgaattag caccgattgc tcgagctcat gggttagaaa aacacgaaac
    24721 aactcgctta aataagcatt ttactcaaat ctatgaaaaa ggattccact tagatatcct
    24781 gcaatctgtt ttcggatcag tcagctgggc tagttttcag atatttcagc tgatttgttt
    24841 gattttcact gggatattag ctttacaagg gcgcatccaa cccggcgatg tcgtgatgta
    24901 tcagacgtat ttcacgacga tcgtcaattc cgtttctgga atgatcacgc tgattcctac
    24961 gatttcaaaa ggcatggaat ctatcacttc tattggcgaa ctgttgattg ctggcgatgt
    25021 agaaacttat cacggtaaga aaaaaatcca acatttggat ggaaattttc gttttgagga
    25081 tgtttctttt ctttatccgg actcactcaa accgattatc gatcattttt ctctagaggt
    25141 gaaagctgga gaaacaattg cttttgttgg gccatctggc tctggaaaat ctacactcct
    25201 taacttattg attggattta tccagccgac ttcaggaaaa atttttctag atgatcagcc
    25261 tttggatgaa ctggatatgc gaagtgtgcg aaattattta gccgttgttc ctcaaaccac
    25321 tttgttgttc tccgcttcga tcaaagagaa catcacttat ggcttgaaaa acgtatcaaa
    25381 agaacgttta gatgaagtca tcgaagctgc gcaactttct tcactgattg accagcttcc
    25441 tgatggtctg gataccttag taggcgaaca tggcaacaag ctgtctggtg gccaaaagca
    25501 acgtatctcc attgcacgag cgttgatacg tcagccaaaa atcattttgc tagatgaagc
    25561 aacctcagct ttagataacc agtcagagaa aaaaatccag caagccctga attacctgac
    25621 agaaacaccc actactttta ttgtggctca tcggctttca acgatcaaag aggcagataa
    25681 aatcgttgtg atcgatgaag gaaaaatcgt tgaaataggt acttacgaaa aactgttagc
    25741 tcaaaaaggc tatttctacc gcttgaaaaa tgaatgacaa aaaataggag ctatgacaag
    25801 acttttgtcg tagctcctat ttctgaataa acggtgttct cctgccaact cctcggtcac
    25861 aagtcacaat agtcatcaaa catgagaagc tgttttttga aattgttcct tgtaactcag
    25921 agttaaacgg taggctcacg acctcttggt aaatggtgtt caagagacag cctatcggca
    25981 ataagaagca attttgtcat cgctcaaggc cgaacgtctc tttcacaccc tctgttgttt
    26041 cataaaatag ttttattcgc tgtaaaggtc gcgaactggt gtcatgatga tacggttcaa
    26101 gtcattgatg attgtactga agccttgctc tttttgcatc aagtcattga ttacttcttc
    26161 tgattggatt ttcacagcca tttcttgtgc tttcattgca tcttcgtcgc tgaactcttg
    26221 tccactcatt tgtttttctt gtaattcgat ttgcatcgct tggaagtctt tgaacagttt
    26281 gtgtgcttct tcgtttgctt gtactttctc gtacgcttct ttcaacgctt tgaattctgg
    26341 taattcacgg atctcacgtt cgatttgatt cgcgctatcg tagatgtttg acatgttatg
    26401 ccctcttttc ttttagtagt tactctctat tgtaacatgg ggttattcgt tttcaaaggg
    26461 gctactctcc ttgatatttc cgccagaggt ctttagccgc ttcaccaatt ccctgaacgc
    26521 cttctttcac catatcgccg aagtttttca gcccttcttt tgcttgttca ccatattgat
    26581 tcaagttatc ttgccaattt ccagactctc cattagaatt tcctgtgttt ccaacttgat
    26641 ctgcagctac cacttgtcct cctgtggcat aggcatctgc tacactaaat cctgtttttg
    26701 aagtatacgg aaggatgcct tctgccgctg atttgaagac tttcccgaca acatttccac
    26761 ttgtcccttc caaatagtgc agcttgctgg attcttcgta acccatccat gtcgaaatca
    26821 ctacgtctgg cgtgtaaccg atcatccatt ggtcatttgc ttttgtggca tcgaaattag
    26881 tttctgtggt tcctgttttc cctgctatcg tataacctgc aggattcgca gcagccgctg
    26941 ttccatttga aaatgtacca agaagcatgc tggtcatttc atcggctgtt tcctttgata
    27001 tgacctgttt tggttttttg tttgtgttat cgacgatcac cgctccagtc gaatcaacga
    27061 ttttcgtgat aagatgcggc gtatacatct gaccatcatt ggcaaatgca ctgtaagcac
    27121 ccgccatgat caatggagat actccttttt ccagtccacc aagggctaag ccataatact
    27181 tatcagattt tgctaaaggc aggccgaatt cttctgcttt atcatatcct ttttgtaaac
    27241 cgatctcatg caaaagccat acagtaggca aattcaaact ttgtgcaaca gcttgataca
    27301 tcggtacttc tccttggtat gtcccgtcaa aattatgcgc atcgtaataa ctttgcggtt
    27361 cgtctttcaa gatactggaa ggcttgtatc cagcttccag tgctggtgta tatacgctta
    27421 atggtttgat cgttgatcct ggtgaacgac gcatctgtgt agcaaagctg aatcctctaa
    27481 agacatgatc tcctcttcgt cctactagtg cttgtacacc acctgtattc ggatctaaag
    27541 ctactgaagc agattggacc atggcaccat ctgaagcatt tgctgggaat aatgcactgt
    27601 tttgataagt agcttctaat tgcttttgat aatcctgatc taaagctgta tagattttat
    27661 agcctttatt catgacatct tcttcatcaa gaccatactc gttaactgct tcatcgatca
    27721 ctgcatcaaa ataataagga taacgataac cagaatctga attatcgtat gtgtcattaa
    27781 gatacgcgct gatatctgtc tggctttctg cttgttcttg ttcttttgtg atttttccgt
    27841 tttcttccat tacacttagt actgtgtttt tccgatcatt cgcatttttt gggtgatcga
    27901 tcggattata aataccagga cctttcagca ttcctgccaa agtagcagcc tcagacagcg
    27961 taacattcgt tgcatctact ccaaaatact ttctggaagc gtcttggaca ccccataccc
    28021 cgttgccaaa ataggcattg ttaagataca tggtcaagat ttcttctttg ctgtacttct
    28081 tttcgatctc gattgccaaa aataattcct tcgcttttcg atcaaacgtt tggtctaatg
    28141 tcagatacgc atttttggca agctgctgag tgatcgtact tcctccgccc cctgatgttc
    28201 cgccagacaa gaccattcgg actgctgcac gggcaatccc tttgatatca aacccgtgat
    28261 gctcgtaaaa attcctatct tctgtcgaga ttactgcatc ttggatatag ggagaaatcg
    28321 cgtttaattc tacatatgtt cctttttggg cgtacagtgt gccagcttct tcgtttttct
    28381 tatcataaat gactgtcgat tggcttaatc ctgattttaa cgtttcgaca tttgcttgtt
    28441 ttgctaaaat aaagaggtag atacttgtca ctaagacaca gatcaaacca atcagcaaaa
    28501 tcaatttgtt cacatgatat tttttccaga tgcgctttcg ccatcgatgg aattgtccga
    28561 gatatggtct gatccaacgc caaaaactga tcaaagcagc ttttatcttt tctaaaatgc
    28621 tttgaaaatc catttgcttc ttctcctgtc tatttgattc aatcgtctta ttttaccata
    28681 gtgaaagagt gttttcttcc tgcttaagtt gtagttcaat atgttttttt acgttagtgc
    28741 aagtagagta acataagaat gaacagaaaa atgtaagttt tttcttaaat atgttttaaa
    28801 aatggtacaa ttagtctgcg attgcactga aaggagtaca cttgtgaaaa tcacgatcac
    28861 tttacctatg aaccatcctg aaacaacaat tcgcgacttg cttgaaaagg aatggttagt
    28921 tcctagaaag gttcgacact ttttgcgtat acgtaaaaac gtttggatca atcaacaacc
    28981 tgctttgttc catcatgaag taaagggcaa tgaccagatc acattgttat tcgaagaaac
    29041 agattataat tatcaagaag ttcaattagg agatgcgaag cacatccgtg ttttatatga
    29101 agatgagcat ttgattatag tggataagcc tgcaggaatg aagactcatc caaatgaacc
    29161 gacagaaaac agtaccttac tcaatcattt agctgcttat ctcgacacta aacagcaacg
    29221 accttacgtt gtccaccgct tggacaaaga aacaagcggt gccgttttat ttgcaaaaaa
    29281 tccatttgtc ttgccgatac ttggaagaat gttggaacaa aaaatgatct atcggagata
    29341 tcaagccatc gtatggggag aaattgccaa agatatgacc atcaccaata aaattggacg
    29401 agatcgccat gatcggagaa aaagggtcgt agatgataaa aatggtcaga gcgccttgac
    29461 acatgtcact gtcaacaaag tactttctga acaaacacaa gtctattgtg ttttggaaac
    29521 cggacgtaca caccagatca gagttcattt agctcataag ggacatccga tcgttggaga
    29581 ccctctctac caaaatagaa cagctgaacg actgatgctc catgcattag aactgcacat
    29641 gatccatcca tttactcaag aaaaaatagt cggtaaagct ttacctggat tatgggaata
    29701 gaaataaaaa agaacagagt cttatcagca gataatgata agactctgtt ctttttgtgt
    29761 aatttgtctg cttacttttg atgttcgtgt tctgctaaca gcaaactacc gataatccca
    29821 ctttcattcg gcagtcccca acgaacgata tattcactta cttgaggtgt ttccatataa
    29881 ccacccatca attcaacaaa ttgctgacgg attttttgaa ggagatgatc ctgattcatt
    29941 accccaccgc ctaaaataat cttttcaggt gctaacgtca acgtatagtt gatcagtgct
    30001 tgagcaatat aataagcctg aatagcccaa acaggatgat cttgcggcag atcttgccct
    30061 ttgatccctg tgcgtgcctc aatagacggt cctgctgcta atccttctaa acaatcttta
    30121 tgataaggac aagtaccttc ataatggtca tctggatggc gtttcaccca aatatgtccc
    30181 atttcaggat gtgcgatccc tgaaaaaatt tcttcattga tcacgacacc tgcaccgatt
    30241 cctgttccca cggtaaggta aatacaacta ttttttcctt gtgctgctcc ttgcttcaat
    30301 tccccatatg cagcagcatt gacatccgtt gtccaagcag caggaatatt gtagcgttcc
    30361 ttgattgtgc caagaaaatc gaattgtgcc cacccttttt tgggagttgc caaaacgtat
    30421 ccgtaattat cttttgtttt gtcgatacca atcgggccga atgagccaat cccgattccc
    30481 ttcaattcat aacgatcaaa aaattcaaat acctgatcca atgtttcttc tggtgttgtg
    30541 gtagggatac ttaatttttc taaaatttct ccaccatctg aaaccgcaca cacaaatttt
    30601 gttccgcctg cttctattcc gccatacatt cgttttcctc ctcgaatccg attgtccgaa
    30661 tctcataagg ttggattatt gggacaaccg cttgcttcgt tggttcttca agcagattca
    30721 atatgacagt ttttccattg tctttagtta tttccaattt ttctaaatga ctagacatat
    30781 tgaaacctct tactactact ttatcactaa acttgctgcg tttcaaagct gtaattgcaa
    30841 acgtttcact ttttatcgtt aaatattgtt gttttgaaat caatgttcct tcatgatgtt
    30901 tgatttgttg agtggaaaaa ggaatctgtg ctgcgtatgc atgcaaataa gtagagaatt
    30961 tttcttctgg tccatgtagt tcaatgctgt aattgaaccg atgctcacct agacactgtg
    31021 cttctggtgt tggaaaatat ccccaatcgc ctagttctcc cacactgcga agtagcgtca
    31081 ctgcgatttg tccgtcttct gttacttcat attcattcaa accaaagttt ccgactgtta
    31141 caccgtactc ttcatcatga atattgacaa atgcttgctg atgttgcgga ttcgtggggt
    31201 tttcccaact tttagacaca tggtttgggc gcttcaccac ttcaaaaata ctatctgctt
    31261 cgtgatgttc cacatgtaac tttgtaggaa acaagacacg taagcgatga tctttcatct
    31321 gattgtcgag agtcgtttca aagtcgattt ttttactatc ttttctgatt gtcatgattg
    31381 tttttatttg aaggattcgt ttttctttgg atcgttctgc ttttcgataa cgaaattcca
    31441 caaccatctg ctgttctttt tctaaacgct cgtctgcaga aacagggatt tccatttcct
    31501 gtagaatact tatttttgct atttccggtg tatctactaa tacttttact tcagagtttt
    31561 ctttgttact ggataggatt ggctgatcac agaaaggttg tttaaagata tactcatttc
    31621 ctatatcgcc gatatcttca aaaatatgca gattattcaa ctttcgtttg tttttgcgat
    31681 cttccattgt aatggtacca tttttttcaa tcgtcaaatg tagagggccg ttttcgatga
    31741 ttcgtccact ctgatgaatc attgtttcct tttcttctgc tttcgcttcc ccttctacaa
    31801 gcgcgaatgt ttcccaagaa aatgctggca tgttttctaa tggtaaagtc actttgatca
    31861 ttcttgccat atatggcaca cggaaacggt ctttcggcaa atcataacca aattggacag
    31921 tttcttcaga taaaatagct ggtatagtgg ccccactttt tgtttctaca tgatacttac
    31981 gtttaggcaa attttctaac tcttgatata gttgttcagg tattccttca gcgaatcttt
    32041 ttctttctaa ttcgatggtt atttctgctt caccagtttt atccattcct gcagtattta
    32101 caatgacaaa tggaaagctg tcttttggga atccggtcgt atcgattgct gcggtcagct
    32161 gttctaagga atcttgtgca agatactttc caacttcatc tgctttttca aaacgaggta
    32221 tcatttcccg atggacagaa tcgactgaac aaccgcaaat actgtcgtga ggatgatttt
    32281 gcattaatgt cttccaagca taatctaatt gatcatgggg atagtttcca ctaacttcat
    32341 aagccatcgt cgcaagtggt tctgtaatat tttctagctg tcgctggacc ttggtattcc
    32401 attgttttaa gtaaacccga gcagatgctg tattggctaa agtataccag ccatccgttt
    32461 cttgacttgt caattctcct tctactgagc ctaagtcttc tggcacatct ttttgaactg
    32521 cttccagata gtcagtaaaa ttagaatgaa taaactcgta atctggaaac agttcatttg
    32581 cgagatggat tgcttttgat atatcttttt gtaccggttg atgatcaaca ccattcatca
    32641 tcaataagtg gttcgtagag gcatattgtt ctgcatccgc taatttttgc ttccaaaagg
    32701 caagagctgc ttctttttct actggaatct cattcccgtt gctataccaa ttggcaaata
    32761 gcagaccaaa gattgctgtt tgatcaggtc ctttccacca catctctgag tattgggaag
    32821 aatagttttc tgcttccaaa acttgattat caaagccaat tggttttaca ccacggccaa
    32881 acgctgctgc tgaaatacca gcttgtttca ttaattgagg cgtctgtccc atatttccaa
    32941 atgtatcggg aaaatagcct aacatgacag gggttcccca tttacggctt tcttccatgc
    33001 caatcagcat atttctcacg ttcgattccg agctgataag aaaatcatct tgcaagatat
    33061 aaaatggtcc aattctcaat tttccttcat tgattgcttg ttggattgcc tgtctttttt
    33121 ctggccttac ttgaagatag tcatctaaaa taatcgtttg cccatccaaa tgaaaactgt
    33181 tgaaggacgg atcaacttca aatagctcta gtagatcgtc tatcaattca atcagtcgca
    33241 tgtgatgctg ttcgtaagcc atgtaccatt cacgatccca gtggctatga gaaatgatat
    33301 atactttctt tttcatttac gatacctcct acttttctac tctaatatca aagtaatcca
    33361 tgactaattc gcaaaacatc atatttgccc aagaaaacca ttctctcgta taattttcag
    33421 gattgttcac atcgaatcct tcgtgcataa ggtgtgttcc tgcgtcagtt gctacaagta
    33481 aattcaatat ccgctctttt tcagatttgt ctgacgttgt cattccttcc atagctaatg
    33541 caatcggcca aacgtatttt tctggcgtat gggaggatcc aattcctttt gcgtactttc
    33601 cttcatagaa atatggattt tctttactca acaatgttct tcttgtttgc agataatctt
    33661 cctcttgttc agaacaatat cccaagtaag gtgcggcgat cagattgggc acattactgt
    33721 catccatgac tgtggcgttt cccattccat ctacttcata tgcataaatc gtttgccctt
    33781 tttgattaac cgttcgtccg tgattctgaa tcccctcttg gatctctttc ttcaatttct
    33841 gtgtttgctg tacaatttct ttatcatcga gtatcgtttg aaaaatttct tccacataac
    33901 ctaacacgac caccgcaaac atattggatg gtaccagata tccataacgg caagtatcat
    33961 cgctaggacg gaaaccagac catgtcattc ctgtaaaagc tgtttttgca cctcgcccgt
    34021 cattgatcag cgtatcttct tttcttgtcg tgtctcgtac aaatgtataa ggagagtgtt
    34081 catgatcttg ctctgttttg aacacgtcca agattttttt gataccttca ataaaagatt
    34141 gattgaattg atcagttttt cctgtatttt tgtaaagaag ataggccaac tgtattgggt
    34201 agcataaaga atcaatttca tattttcttt cccagatcca atcgttcatt tttgtatgat
    34261 ctgtttggtg gccagcaccg ttagcttctt cgttgaaggc attcgcatat ggatcgatat
    34321 tgatataaaa aaattgcttt ttgactaacc cgctgatcat gtcagctaat tcctcatctt
    34381 cttttgcaat cactaaataa ggacgaactt gtgcagtaga gtctcttaac cacatcgctg
    34441 gaatgtctcc cgtcaataaa aaggtggttc cgtcattttg ctttttgact gttgtcaaca
    34501 gagtattggc aaatgctgct gtaaaattct ttgcccagtc cgcatggata tccccacatt
    34561 tttgtgtgat atcttccata aatttctgca ccgattttgg tatatcttta taagccacta
    34621 ataaaacctt ctttctattt gatatatctt taaagattat acttcataca gccaattatg
    34681 tctacgcttt caaaaaatat ctttttattt actttttcat ccattatggt attatttgaa
    34741 tatgatatat cattaagagg tgtttatatg aatcaaccat tgtaccagac aatatttaat
    34801 gatttgcaaa cggctatttt aactggtgaa ttacctgtag acagccaact accaactgaa
    34861 aaagaacttt cacgtaccta taaagtaagc agaatcactt ccaaacgtgc attgactgaa
    34921 ttagagcaat taggacttat ttatcgcgtt cgcgggaaag gcagtttcgt taaatccgct
    34981 tctccggaac agattcttgc ttctcctaca aaaacacgac ggattctgtt tcttcttcca
    35041 tatgtcgctg atttgtctgt tggtgatttt agcaagggat tgaaccctgt gatgcaagat
    35101 aaacagattg atgtcatgat gacgacgctt gactttctac aaaataaaac agcaaaagag
    35161 ctaatcaatg aatttgacgg attgatttat tatgctcttg atacagaaca acatcttgac
    35221 ttactttttg agctttcatt gaaagaattc cctgtcgtca tattagataa aaaaatctat
    35281 gagttacctt ttcctaccgt tctttccgat aatttccaag gcggtgcgct tgctgcctct
    35341 tatttgatcg aacagggaca ttcaaaaatc gcttatttgt ttggtacgca gactcatcca
    35401 caatccgttc gacagcgtta ccttggttac cttgaagcat tggacaaagc tggtttgact
    35461 ttccacactt cactggatga caaaagcgcg acattagatg aattgctttc ttatatcact
    35521 aagtatgaag taactgcttt tgtttgtgaa aacgatgttg tcgctatcca gaccatgaat
    35581 ctcttgagac agcatggtta tcatatccct gaagattttt caattatcgg atttgatgat
    35641 atccaagcag cagctcttgt tgacccgcca ctgacaacca tcgcacaaga ttttgaacag
    35701 ttaggtaagc ttgcgggaga tgctttggtc acttggttag agacaaaaga tcgaccatcc
    35761 gatagtaaat ttccagtttc attcatcaaa agacaatcaa caaaggagaa ataaaatgaa
    35821 tatcggtcaa atagatacta gacatgcaac agcgaatcag ccaaatttct ctaatgggaa
    35881 ctgccagcct tatactggcg ttccttttgg gatgaattat tttgcaccgc aaactacgga
    35941 tcaaaacggc agctggtggt ttcatcctga tgaccgcgtt tttcaaggct accgtcttac
    36001 ccatcaacca agtccttgga tgggtgattt cagtcatatg ctgtttacgc cgatcaatgg
    36061 aaaactacag gagaacaccc ttttccatgc tcaaagttct taccgcccag aagaaagtat
    36121 attttgcccg actcatctgt cgatctgtca attacgttat ggcatctgtt ctacattgat
    36181 acctagcatg tatggcggaa tcttatctat tgattacagc aaaaatgaca gcggtttact
    36241 tttatccttt ccgggacgcc atcagctctt tgttatagat ccttacacag tggaaggaaa
    36301 aatcacacat tttgctggtt cagaagatcc tgatttttct ttttatttta tattgagatt
    36361 tgaatatcct ttaacaattg atgagttagc tgtttccaac aaaaatagcg actcgatccc
    36421 gttgtatttt gaacagacaa aaaaacaaac tatccgattt gggacatctt ttatcagctc
    36481 ggaacaagca gcttataacc tggaactaga acaaaaccaa agcaaagaga cttaccttgc
    36541 tcacagtcaa gaacaatggc agtcctattt tgatcgtata cagctcacac accatgatca
    36601 acaacaattg cggacgtttt atcataattt atatcgggtg tttttatttc cacaaacatt
    36661 ttatgaaatt gatcctagtg ggcaaaaaat ccactatgat acgactagtc gatctataaa
    36721 acctggtgtt ctctatacaa ataatgggtt ttgggatacg tataaaacgg tttatcctct
    36781 ttattctttg attgctgtag aaaaatacga agaaatgctg gaaggttttt tgaacagcta
    36841 tagagaaagt ggctatttgc caaaatggct gtctcctgat gaacgtggac ttatgcctgg
    36901 gacattgatc gatgcggtca ttgcagatgc tgctgtaaaa gatatccgac gagacttgat
    36961 gcctgaattt ctaacggcaa tggaaaaagg tgctacggtt caaagcaaac atccaaatta
    37021 tggacgccaa ggaacagaag attacttgac atatggctat gttcctaatc actaccacga
    37081 atcagtcaat cacacattag actatgctta tagcgatttt tgtattagcc aagttgccaa
    37141 ggtactagaa gaagaggaaa tgacgaagaa atatcagcag caatcattga actatcaaaa
    37201 tatctttgac tatgagtcag gatttatgcg ttcaaaagat aaagatggca agttcagaga
    37261 accattttca gctaatcgtt ggggacaaga ttatgcagaa ggaagtgctt ggcaaagcag
    37321 ctttgctgtt tatcacgatt tttcaggact gatcggaaaa tatggtggca gtgagagata
    37381 taaagaaaaa ctcattgagc tgtgcaatca gcccccaacg tttgacccag gaggatatgg
    37441 ttttgagatc cacgaaatga gtgagatggc cgcgatagaa tttggacaat tagctatttc
    37501 aaaccagcca agttttcact atccttactt gttcagttat ataggacaac ctgaaatggc
    37561 acagccactg cttaaacagt tgatgactca gaccttcgac gattctccaa tgggttaccc
    37621 tggagatgag gacaatggaa gtatggccgc ttggtatatc ttcaatagtc tgggatttta
    37681 tcctgtcacg cctggaaccg gtgaatatgt tatcggtatg ccattaattg acaaggctgt
    37741 tttgcttttg tcaaatggaa aggaattgac gattgaagca acgcctaatc ggccgcagca
    37801 acaatttatc cataaaatca aacggatgga caaagaatat acgaaattat attttaccca
    37861 tcaagatttg ctgaaaggcg gcacgatctc ttaccaatta gggatcatcc ctcaccctaa
    37921 gaaatatcaa gcaaaagatt tgcctttttc cttatcaaac tataattaac aagaggttgt
    37981 gaaaaagctg tcctgcatca agtaataaga acagccaagc aaaaatagat cctcatattt
    38041 ttcgtttggt tggtcttatt accgcagatg caagcttttg aacaccgttt attgagaggt
    38101 tgtgaaatca gcgttctgac ctgagtatta gagagacaaa tggcaaaata gttcctcata
    38161 ttttgccatt ttttgagcta ataccgaggg tcagctgatt gaacaccgtt tagtggagag
    38221 gtcgtgaaaa agctgtttag tttcgagtat taagaaaaat tttgtgaaaa tggctttcca
    38281 catttttgca taaatttggc ttaataccga gaaactggct tttgaactcc gtttatcgag
    38341 aggtcatgaa aaagctgcct tgcctcaagt aataagaaca gcccaaaatt agatttctag
    38401 acaatttttt ataagttatt tcattacatt ggctttttct tttatgattc tccactgttt
    38461 tctcggtact ctttagggga tctgccgacg attttcttga ataatttaga gaaatacgtg
    38521 gtgttgttgt agccaatctc acttgctatc tcattgatgt tttgattact gtgcaaaagc
    38581 agttgtttcg ctttttccat acgtaaatgg ttcaaataag ctgaaaaact ttttttcgtt
    38641 tcttttttga acagctgtcc tagatacatg acatttaaat gcaggttttc tgacacttct
    38701 ttgagtgtaa gtggttcttg ataatgctgg tgcaggatta cgattacttt ttccacattg
    38761 tcactgtact ttttctgtct ctgatgcttt ttgatgaatg acagaagtag ctgctgaagt
    38821 tcttgcaccg tttttgcctg atggattttt tcgattcctt gtaaatattc ctcatcttcc
    38881 agatcaatca attcccgttg aatctccata aacagtaaaa aactggaata tcgtatatct
    38941 tccggcatca tggctgctaa ctgaaactgt tcaaaaaaat cagtgatcat tttttgagcg
    39001 acttccaatt gtttattttg cagcacgcgt ctgaaacttg aaaaatcgat ggtttgatct
    39061 tttgtttctg cttgtactgc gtaaaaaaca tgctcgtctt tatctccata aaattgatgc
    39121 aactgtagat tgtctttcgc ttgttggaat gtttcaggga ttttgtccaa agaatctgtc
    39181 tcttccccga tactgatcag ccattcctga tcaggaaagt tttcttgaac aaaacaacag
    39241 aagccatcaa cttcatctgc ctccaacaac aacgtgatca atacacggtc tccgtaattt
    39301 cgttgatagt aaaagatttg ttgccgttct tgcaaccatc tattgataag agtatcatga
    39361 gttcttgcca gttgaatcaa tactatccta tgctgcttct cacttatttg tcctattatt
    39421 tcttcttcac ttatttcatc caattcttca ttcaaccatt gactgaataa cagttcttga
    39481 tagatttctt gttgattttt ttgttcattt tgctgatcta accgtgtttt gattttcttg
    39541 aggctttcaa ccaattcgaa cttattcacg ggtttcatca aataattcac ggcgcctaat
    39601 tgcatacctc ctttcaaata atcgaattct tggtatcctg ataaaatcat aaattcaaaa
    39661 ttatgacgtt ctttttgagc cgcttcaata aattccagtc catttatttc tggcattgtc
    39721 acatccgtta ctactaaatc aatctgtcgc tgttcaagta cagctagtcc ttctttggca
    39781 ttctctgctg ttgctactat ttgaaagcct aaactttgcc aatcaattat cttttttaac
    39841 ccattcaaaa tcatgtattc atcatctacc aataacactt gatacacgct catccctcct
    39901 tgaatgtaat agaaacggtc agtccacctg tctcattatt ctcaagcgac atataataac
    39961 tgctgccgaa gctggcacgt aaacgttcat tcacgttttg cagaccgata gaaccgtgaa
    40021 gttccacttt aggatgagac agtttttctt caatctgttt tagccgtttt tcagtcatcc
    40081 cttttccatt atctttgatg atgatcctta cccgtttgcc ttcctgcaag actttgacac
    40141 ttagcgcatt atcgaatcga gtaaaatcaa taccgtgttt aaaataattt tcaactaatg
    40201 gctggatcac aaatttaggt acttcgatct tttccaaatc aggatcgatc ataaaatgat
    40261 aggctactcg attaggataa cgcatttgat acaaatagac atatttttcg caaaagtcca
    40321 gttcttcttt taaagtgatc gttttctctt gattcgtatt gtttcgaagc aaagcggaaa
    40381 acgcatacac aacatctgct aattcttcac ttccttcgct gattgcatac attcggatat
    40441 attctaatgt attatataaa aagtgtggat tgatctgtgc ttgaagcgcc cgcatatgtg
    40501 cgtcttgctg tttgatttct aatttgtaga tgtcttctac aaactgattg atgctatcca
    40561 acatttcgtt gataccgatt gaaagttcct tcagttcata ttccgtgttt gttatgtcga
    40621 tccgcgtctc taaattccct gctgctgttt gatccatggc ctgcatgacg atagatactt
    40681 gctgtgaata tcgtttgaat gttttataaa gaaagataag cagtatattg tctaaaataa
    40741 tgataccaat gatcagcggg gcaagatttt ttcccgtttc gatttttaca ctttttttat
    40801 ctagtacagc taatatacga taatcatcag acagttcttg gtgttgaaca aaattgtttt
    40861 tttccagatc gtcaatcggc aattgtgaat ttttcttcag actctctgtg atgatcattt
    40921 cttgtctttc aaacgtttct ttagctattt tattatcatg gaatgtgtat agtcgatttg
    40981 tcgttccaga aatcatgtat aaagagagtc cattgaatga cgttagattt tctaaaatca
    41041 tatctagttc tttcttttga aaaccaataa aaatacttcc tgactcagct cctccttgtg
    41101 tgataggcaa cttgatataa aaggcgtcta gtaattttgg tgtccccttt tttatttccc
    41161 cacctttgtt ttctctagaa gattcataat actccggtag ttgattcaac acgatatata
    41221 tcgcacttag ttcttcataa tttgcgtaga gatctttgat ttgatttggg aaagaaacta
    41281 attcatcggt actgttttgc tgttcgtata catacatcag atactgatct atgggttttg
    41341 ttaagtaggt cgtcacattt tcgatctttt cggaattccc tacaagctgg tttttgatga
    41401 tcctactcaa ggttgtttta tcattcagca ttctgcttgt gctttgaacg gcatcacttg
    41461 tcatgttttc tgcctgtttt tgattttgtt cccaagtatg gatactaaaa ataacggtag
    41521 cagtcatcgt tacaccgatc atgataaccg cgtatttccg caacagacga tttagtaagg
    41581 ttccttttga aaatagaatc cgaaacttat tcataacttt ccaactgttt atctaattct
    41641 tcacgccaat gtgttgtcat cgtaccattc caaaccgtca aaagaccaat gacaccaaac
    41701 aggatcaatc ctttgaattg ccaagtcacg cctaaaatta taccgctacc aataattatt
    41761 tttagaaaag acgaaaagct ggaaaaaacc gaaataaaac ttagctttag cagattagga
    41821 acagagatcg tatattcact atctaaaatc atactgtatt gataagtagc aaataggcag
    41881 agcaaggcaa aaagtaaaat aaaatcaata gctaaaaaaa tgagcccttt gatttgaaca
    41941 gataaatata aattgtaact caataaagca gtaccagata aaaataaact aaatagcaga
    42001 ttgcctctta aaaaatttct tttatatata ttccagcctc tttttattgt gatttcttta
    42061 tactcgaatc cgtacaaata aaatagttca ttgactgttt tccatgccgc acctaatcca
    42121 aagatgatcc cgccggcaaa tgtatatatc cagaaataca aggttagttt tataatgacc
    42181 cagatccgga taaataactc ttccaaaacc ttccctaaca tatcttctcc tccaaacatt
    42241 aagtttatac tttctcatta tacaaaaaaa ggttgggcaa tcagcacctt gacctgatta
    42301 ttagagaaac aaacggaaaa atagttcctc atattttgtc gttttgtgag cgaataccga
    42361 gggttagctg attgaacacc gtttaccaag agtttgtgaa atagccgctt agtttcgagt
    42421 agtaagaaaa attttgtgaa tatggctttc cacattttta catatattta gcttaatacc
    42481 gagaaactgg cttttgaaca ccgtttattc ggaacaagag gttgtgacac gtcttttgtc
    42541 acaacccctt tgtctttatt cattattatt cttgtcggaa ctcatcatat tgtttttgca
    42601 tttctttcaa taccttatca tagccagcct tgtccaaagc gtctttcaat ttcggtaatg
    42661 tttcatctgg atcaacagtc cctgtattca atccatctaa atattgattc atgacattag
    42721 aaatattact taattctgtt ttgacactgt cagtgttgaa gctgaatcct aaaatcggtg
    42781 aagtttctgc atcagcaatc gattgatcac gtttggcaat catgtcatcc gtaatagact
    42841 cttgtgtata tagaatcttg ttgtttcctg tattccaagc agacatatgt gtatttggct
    42901 gataaccatc tagcaatttg attttatcat ctgaaccatc gactttttcc catgcttctc
    42961 cctcgatccc ccaaacaagc ccattcaata attctggatc actgttaagc agccctagaa
    43021 gttctactga tttttcttta ttttttgaag tatttgatac gacaaaattt gccatttgtg
    43081 cttgagctgt agattttagt ggaacagtaa ttgcttttga gacaagttct tgttttgctg
    43141 catttgtcaa aattgtatcg ccataatcat acggtccttg tgtttctcca cgcattagcc
    43201 aagtatttcc ttctagtgga taatccttat tgctcgttgc agcgtcactt ggaatgagtc
    43261 cttgtttgta ccagctatgc attgtacgta acagtccgat atacgtttca ttatcgtatt
    43321 ggttgatgat tttcgaatca tctccatcca gatcaatagc aaatggtaac gtattcccta
    43381 aaggataatc aaagttccct tggactttga agccttgtcc aatggcaaaa gctgccgtgt
    43441 ttggttcttt ttcatggaat tccttcaaga ctttttctgc atcagcgtaa gattggattc
    43501 catcaattga aagatcgtat ttatctagta aagctttgtt aaaagtaagt acttgttgag
    43561 caaagacatt tccattgact gggaaagcat ataattttcc attgaccaga tttcctttaa
    43621 tatatgcttc atctaaatca ttataagctt tttcagcgta cttaggcgct aattcagtca
    43681 aatcagcaaa ggctcctttt tgggcattgg aaacatagtt gttcgcaaag gcgatatcat
    43741 aattttcccc ggaagaaatg atgacgttca ttttcttttc gtaatcgccc cagccaatgt
    43801 aattgatatt gacttttaca ccgatctctt tttcgattcg tttgtttgct acttccatca
    43861 attgatcgaa attatctggt ttatctccga tttgatacat ctgcaaagtg tccgaattgc
    43921 tagcttctgc ctggtcttta gaaccagaac ctccgcatgc tgctaatgtt cccaacaaca
    43981 acgctgaaac acctgtaaag gctagtttct tccataactt catttttctt cctcctaatt
    44041 ttatgattta tatttttgtt tctttattct tttactccgc cgattgttag acctttgaca
    44101 aaatgcttct ggaaaaatgg atagctgatc gcaataggca acgtcgagat gactacgatc
    44161 gccattctgg cagattctcc tggaactgag gctaatccgc ctgtcaattg gcttcctgct
    44221 cctgaatttt gtgtcagata ttgaatatta ctttggattt tcatcaaaag atactgtagt
    44281 ggaactagct tatcatcttg gatgtatagt aaagcattga accagtcatt ccagtaaccc
    44341 aatgcggcaa ataaactgat tgtcgcaata cctggaacag ctaacggtaa aacgatctga
    44401 acaaatattc gcagttcgct agctccatcg atccgtgccg attcaataat cgaatcagag
    44461 accgaacgtt taaagaatgt gcgcatcaca ataatattga agggactgac agccattggc
    44521 aagatcaatg cccaaatcgt atcttttaac tgaagaagat ttgtcataac aagataattg
    44581 gccaccatcc ctggtgagaa caacatcgta atcaaacaaa aaacggtaaa aaaacgacgg
    44641 aatggaaagt ttgaccgtga aatcgcataa gcatataaag aagtagccgt gctattgatc
    44701 agtgtaccta aaacagtaac aagtacagtg acgaaaagcg cttggaaaat tttatcctgc
    44761 atctggtcga acaagtacgt ataaccaaat atactgaact tttctggcca aaaactgtac
    44821 ccgtgagtcg acaatatgga ctcatcggta aaagagatgg cgataacaaa tataaatggc
    44881 aaaatacagg aaatagcaaa gagtgcaatc attatattag agaaaaaatt agccgtctta
    44941 ttgaaagagc ggacttggac tctctccact ttcttttttt tcattttttt cctccttaga
    45001 ataatgcaga atcgctatca aaacgtcggg cgatcgtatt tgtgatcatc aacaagacaa
    45061 agccgacaac tgattggtaa agtcctgcag cagccgtcat accaaaatct cctgtggatg
    45121 tcaggccatt gtagatatac gtatccaaaa cttgagtcac atcatataat gcaccggaat
    45181 tcctaggaat gttataaaac aggccaaaat cagctcggaa aatgtttcct acggctaaaa
    45241 tcgttaaaat cgtcattagt ggaataagtt gtggtatcgt cacatgtttg atctgctgcc
    45301 atttgctagc tccatcaacc atagcagctt cataataagt cggatcgatt cccataacag
    45361 atgcaaagta aataatgctg ttataaccaa tccctttcca tgtaccaatg aacaccaaga
    45421 taaacggcca atatttcggt tcattatacc aattgacagc ttctcctcca tgtccagtga
    45481 tccactgatt gaatattcct ttgtcaggac ttaaaaaagc gtaaacaaag taactgataa
    45541 tgacccaaga tagaaaataa ggtagtaagg acatcgtttg ataaacttta acgagtcgtt
    45601 tatttctcaa ctcgctcata atgattgcaa atacgactga gatcagcaga ttcaaaagga
    45661 taaatgctac attatataaa attgtatttt tagtgatgag aaatgcttga tccgaagaaa
    45721 ataaaaattt gaaattttcc caacccaccc aaggactttc cctcaagcta gccaagaacc
    45781 catctgctga aatatgaaaa tttttgaatg ctacgacatt cgccattaca ggtatgtaaa
    45841 agaaaaaaat catccaaagc atacccggta cagccatcag gacaagtgct ttataacgcc
    45901 atagattcat aaaaaaatga ttgaacccct ttcgtttttt catctaaaaa cccctttcga
    45961 ttcattcgca acgtaattat agcgctttca ataatgagaa taaataaaca aagtataggg
    46021 aaaatgaaac aaagtatagg agaggttgtg aaatcagcgt tttggcctga gtattagaga
    46081 aaaaaacggg aaaatagttc ctcatatttt gccgtttttt gagctaatac cgagggtcag
    46141 ctgattgaac accgtttatc agaggttgtg aattcagcgt tttggcctga gtattaggga
    46201 gatcgtgtcc ttactatcta actctgagtc acaaggaaca atggggactg taacaaaagt
    46261 cttgtcacag tcccttattc cgaacaaacg gtgttccaga agtagcttct acggaaataa
    46321 gccgaaattt cacaaaaaag ccatccgaaa gtcagacgga caagtctgct tttcagatgg
    46381 cgctacaact actctgctta ttcttttagc tatccattca attatttttc tctcacttgt
    46441 tctagctctt ctttggtcat gggtcgatat tgccctttat tcaaatcttt aggcagccaa
    46501 aattttccca tacggattct ttttaaatat aagacttctt ttcctactgc tttgaccatt
    46561 cgcttaactt ggtgaaactt tccttcatgc aaaatcagac ggataattga agtttctgtc
    46621 tcttgatcta cttgatcaat ttggagtttt gccggcaatg tctgctcatc gccatcaata
    46681 atcagtcctt ctgcaaataa acggatatct tcttctgtca ttataccgct aacctcagct
    46741 agatattctt tctccacatg ttttttaggt gatagtaact gatgggcaaa caccccgtca
    46801 ttcgttaaaa tcaagaggcc ctctgtgtct ttatctaatc ggccgactgg aaaaagatct
    46861 tcccgataat cctggtcttc caataaatcg attacggttt gatcatgatt atcctgagta
    46921 gcagaaatga ctcctgcagg tttatgcaaa atgtagtaaa aatctttttg atacgtaatg
    46981 atttctccta aataagtaac cgcatcttcg aattcattta cttgcgcttt atcgcttttc
    47041 accacttgtc cattgacttc gatcgttcct tttttgatta atcctttgac ttctttgcgg
    47101 ctgccaagtc ccatatctgc taaaaactta tctaaacgca tgcgtttccc ccatttcaaa
    47161 agagcatcaa tctagctctt ctgattcact tattttattt ttaatttatg tcgtaaacgc
    47221 gctattcctg gtcctagtag tctttctgcc aagcggattt tcaaagctaa ataaccatac
    47281 actaaagccc ctatacctgc tactacaaga atcaacaata gagactggaa tttgctatct
    47341 tcgtttaaaa aagcaccaaa aatcatcttt gtgatccacg aagccaaaag cataatcaag
    47401 gtaagaataa agatcagcaa tgtcctgcgc cagacaaaac ttggtttaaa gcgggctact
    47461 tcatggattc tctttaagat caaggtacaa gacacagcaa atccgatcat tgtcgccaat
    47521 aaagggccgt atacttcaaa taaacgaatg gctgggtatt gaagaaggag tttcactaga
    47581 aacccaataa ccaaataatt aattgccgcc ttgttttcaa acattccttg cagcatgttg
    47641 gaaactagca tatatagtcc taggaagagt cctacaaaac ttgcttggat cagtacatta
    47701 cttcctagag aatccggtgt ataaaataat gtatttagcg gataggcaag taacataaca
    47761 ccaaatgtcg ccggaaacat aaaaaatgaa aacaactgta aatttccgct tgtcaatttt
    47821 gccagaccta ctcgatcttt caacgtaaca gcttctgtaa tcaacggtaa cccagtagac
    47881 gcgatcgatg ttgccaatgc aataactacc atcgtcaact tatctggatt ggcactaaaa
    47941 atcgaaaaaa gatccagtaa ctgtgcattg gaatactcgg tggatgcaga catgatcttc
    48001 ataaaagtga actgatcgac taatttgaag atcgttaccc ctgaacccac aataataaac
    48061 ggaatcgctt ctttaacggt atctaacaac aattccttcg ttgcaatatt tattttgttt
    48121 tcgctgtagt gaataaacgc cgatgtatac gcttgatgtt tcttcaaaaa atacaaaagg
    48181 acaagaatac ttgctagcat accgataaat gccgcgaaag ttgattgcgt gaccgccgtc
    48241 acatagtcac catccatgac tttcatgatg atgaatgtag ccaatagcat ataaaaaata
    48301 cgtgccacct gttctacaat ctgcgacagc gcataaggca tcatttcttg attgccttgc
    48361 aaataccctc gtatcacact catacaagga aaaaccaata cagcgatact caaagaacgc
    48421 atcgttggaa tcagttcttc tccgccacca gaagcatgag ctagccaagg agaggcgatg
    48481 tacatgaaca aagcaaacaa caggcctaac ccgcccatca tctgtaatgc acggataaat
    48541 aatcgtcgtg aagtgccata ttcattcaat gaattatagc gtgcagtttg ttttgcaatc
    48601 gcagcaggta ttcctgctgt agagatcagt agaaacaatg catatatatt gtatcccata
    48661 ttgaataatc cattggcagc cttagcattt tcgcccatcc aagcatacca gggaatgata
    48721 tagacagcgc ctagcaatct tgaaatgata ttactggcgg tcatccaagc agagcctcgt
    48781 gccatttttt cttgcggtgt taattgatct aatgctggtt ttctttgatt atccatcggt
    48841 cagattccaa ctttctacaa aacattacta tcattttaat tggtaaaaca gaaactggca
    48901 atcgatttta tataactttt ataagaacaa ttgttttttt gaattcggtt tcgttttttt
    48961 ggtaaagtaa agaaatatac agccttttat ggctaacatt tataggagat atcaatgaca
    49021 caagaaataa aaaaactacc cgttatattt ttaggtcttt tctttatcac agttggattg
    49081 aattggttct tgctccctca cgatatagct tccgccggag tgggcgccat cggacattta
    49141 gttgaaacgg ccttttctat ccaacgctca gttactgttt ggagcatcaa tcttatgatg
    49201 ctgcttctag ccgctgtcct attaggaaaa tcagtatttt ttaagactgt agcgggaagt
    49261 ctgctttttc ctgttgtttt agagattgtt ccaaaagtgg aaatgatctc ctcacatttc
    49321 ttttcactga tttcaggaag tcttttgttc agtcttgggg tttacacatt gtacacagtc
    49381 ggggcctcaa atggcggtat aacgataccg ccgattattt tccacaaatt ttttcggctt
    49441 ccaatgccgc aaggactttt acttaccaat agtcttatcg tctttttgaa ttattatgtt
    49501 tttggattgt tggagacact attcgttctc ctatctatta cagtcagttc attgtttatg
    49561 aaaatactca tccgcttgtc ccctgtgtca agaaaatttg aataaagctg gattttgtca
    49621 tagcggaaac aaacgatata ttaaaaagag tgtgctataa taaaccaaga aattgaataa
    49681 agcgagggat caatcaatga gcttctcttt agaagacatc cgtcatttac tattaaaaga
    49741 aaatctatta aaagaatttg tttcaacaag aggctggcat cttgatgtac cagaaaaagc
    49801 tgaatttctt cagttaagtt atgattcaag aaaagctgat gcttctactt tgtttttctg
    49861 taaaggaatg aatttcaaag aagaatattt ggattcagca atcgaacagg gtattcaata
    49921 ttatgtatca gaacaaccat acgaaaattc agcagtagga atcatcgtaa cggatatccg
    49981 taaagcaatg gcgcttcttg ctatggcttt ttacgactat ccgcaaaata aattgaaagt
    50041 gatcggattc actggaacaa aaggtaaaac aactgctgcg tactttacaa aagcaatctt
    50101 ggatcacaca acaaataaaa aaacagcatt gctttctact atgaatacaa cgttagatgg
    50161 caaaacatat ttcaaatccc atttgacaac gcctgagtca ttagatttat atcgtatgat
    50221 gtcagaagca gttgaaaatg gtatgactca tctagtgatg gaagtttctt cacaagctta
    50281 caaaacacaa cgcgtatacg gcttgacttt agatgtcgga atcttcttga atatctcgcc
    50341 tgaccatatc agtccgatcg aacatccgac atttgatgac tatttctatt gcaagcgaca
    50401 attgatcttg aattcaaaaa cagttgtttt aaatcatgaa agtgactatt ttgatttact
    50461 tagggaaaca gccgatctat tccagattcc aacgatcact tatggtcgtt cggaagaaag
    50521 caattatcaa gtgatccgtt cagataaagg tactcacggt tttactttat cttctcatga
    50581 agatcgctta gctatctgcg atactgctta tgatattttg ctggctggag gattcaacca
    50641 agaaaatgca gccagtgcga tcattgccgc agcactaaca ggtgcctcca gtcaagatgc
    50701 acaagacgga ttaaaagaag ctcgtgtacc aggccgaatg gatcaattga tccaatccaa
    50761 tggagcgcat gtctatgtgg actatgcaca taattatcta agcttgaaaa cattgctgaa
    50821 atttgccaaa aatgaacatc cagatggccg tgtaattgtt gtattaggca gcccaggaaa
    50881 caaagcaatc tcccgtcgac atgattttgg aaaagtgcta tcagaaacag ctgacatcgc
    50941 ctttttgacg gcagatgacc cagcatttga agatccgaaa aaaatcgcgg aagaaatcaa
    51001 tgaagcaatt actaatccag atttgatcgt tcattatgaa atggatcgtc ctgaagcgat
    51061 tcgacgcgct ttagcagaaa gcgctccgca agattcagtc gttattgcgg gaaaaggcgt
    51121 ggatccctat caaaaaatca atggtgtaga tgaaccttat gaaggggatt atgcaatcgt
    51181 gaagcggttg attgaagaat aatggtattt atatactagt ggtttcccat ttctaagaaa
    51241 aaaagggact gtgatttttt gtcacagttc cttttttctt agaaatcatt ttaacttttc
    51301 actagctaat tctgctgcct tttctctttc ttcatttaat aatttattat catagaattt
    51361 gataaatggg aaccagataa tgaatgcgat gattgcacaa atgactgcta acacagcagc
    51421 tttccaatca ccaccactac caacaaatgc tccgatcccg actggtgaag gccacggcat
    51481 ctgtgcaagc atcggtttga cgatttccag ccgaatggca aaataagcga gtgtagcaga
    51541 agccatcgga gctaagaaaa acggaaccgc taaataggga ttgtagacga ttggcatccc
    51601 gaaaatgatt ggttcattga tattgaataa tcctggtaca agtgaggctt ttcctaacac
    51661 tttcagctga tcagatttcg cgaggaatgc aataaagatg atcaatccta aagtcgcacc
    51721 tgatccacca acggttacat aagaattgtt gaattctcct gccaacggat aatttgcgcc
    51781 ttgtgcgtta gctgccatat tagctaatac gatcggggtc aagaaagaag tgatgatatt
    51841 cgctccatgg atccctacga tccacaatgc atggatcaag aaataaatca ccatgacacc
    51901 aagccatgta ttcgtcaact gcgtaacaaa cccaaatgag atagcaatca ttttgaagat
    51961 atccgttcct agtgcaacta ataatccatt gatgatcatc accacaaacg caatgacaaa
    52021 tgttgggatc agagcagtga aagaacgaga aactcctggc ggaacaacat ctggcatttt
    52081 tatgacccaa tttctcttga cacacataca atacaattcg accgcaataa tcgacataat
    52141 aatagctgta aagattcctg aagttcctaa acgttcgaca aaagagccca tcctaatacc
    52201 atttactaca gtttctgtct cattgataga agcaatcaag ctgattttac catcagtcat
    52261 gatcaattca gggatacaca taaagaatgc aaaaacagat agtaatgccc ccgtgagcgg
    52321 attaacattt aatttttgtt catctcgttc aattgacgtt aattcataag caaacacaat
    52381 ggcaaagtaa atagataaaa tccccatcgt cattgtattg acgatcatgt acaagtcact
    52441 aactttgaaa aaagttgcat taaaaaatcc ttctaaaaat gggaacggta atggcaaaat
    52501 atttaaaacc aaaaacatcg agcctacaat cgtgaaagga atagaagcca tccccgctgc
    52561 catgacagcc cgaacgattt taagttgcgc aattttcccc ataggtccca tcaggtattt
    52621 ctgcaaaaaa tcaaacatta gttattctcc tttcctaaat ataacgcttt ttcatattgt
    52681 ttaatacgga tatactgttg gtcttggttg agtgaaattt tctttaaacg atactgtata
    52741 aatgcactgg caaaaatacc gcttacaaca agaatgaaaa caaataactg tcctccattg
    52801 ttatttgcca taaaaggata caagaatgta aatcctgagg taaacaacac tggaatcact
    52861 aataaattaa agacactctg gaacaaaaaa taccactttg tccatggaac gttcgtttgg
    52921 tgttttcgat aaagctttac ttgttctcct actgcaggca aaatagctaa aatcagaatc
    52981 atcggtaaac tacttcctaa acttttagct gatagaagca gaatcatcca ttgcatgttc
    53041 atgaaaaaga aaaaggcagt caggtaacgt acgattagat aacgattgaa atacatgttt
    53101 ttcaaactaa gttgcttttt ttctaattcg attttccttt ttactgtatc ctgcacaatg
    53161 atccttcctt tctatttatt tttttgatac aaataattca tttcctgtgc aacttccaat
    53221 aatgtcatcg tcgtcatcag atgatcttgt gcatggacca tgataatttc catttctatt
    53281 tttgtcccgc tggcatattc tttcagaagt tgagtttgtg actgatgcgc atgaagaatc
    53341 tcttcatttg cttgtcgcaa cttctcttct acttcttcaa acatctcttt acgcatcgag
    53401 cgaaatgctt catgtatcag tgtccgtgca tttccgctat ggaaaatgat atcaaaagaa
    53461 gtcacttgta gtgtttcact gtttattttt tcagccatct gttttcctcc ttattcgatc
    53521 agtttgataa atttactgct gaaattctca aaaataggtt cagctaagat ttcctgctgt
    53581 acttttagct ggtcaactaa cctaacgatt gctttagtca cgaccgtaat tccttcattt
    53641 tcgacataag aaggcgaaac taaaaaaaca aaatgaattt cttgatattg atcccactgc
    53701 atcccagaag gaatcaatgc aacggctacc tttgtttcga ttccaactgg aacagcggga
    53761 tgtgggactg ccactgtatc actgaatatg atttgtccca tattttcacg ttgctggatc
    53821 tgctttcgca tttctcttat atatccttct tcttcattta tgctcagctt ttgcagcaaa
    53881 tcatgaagaa tttcttcctt tttcggttcg tacgtataag tcttgaaaaa tttttcagac
    53941 aactgttcgg tgtaaatctg ctttttttgc tgtagagaaa atgctggtat cggtctatct
    54001 gaggaatgat agggtataga ttctccaact acctttcgta ttttacgaac atcatcttca
    54061 ttcaaaaaaa tactgacatg taaaactgga attttgaaaa acattgtcga aagatcaata
    54121 gaagaaataa tcaggtcgat tccttttaaa gttgtttcat tgatctcata atagcctttt
    54181 acacttacca ctgtaatatt tttaccgaat tcactgacta cgcgattctt taatagttgg
    54241 gcactgccgt aacccgttgc acagataatc aatgcatgta gtttatgcgc agctctttct
    54301 ttttccaatg ccgccatgag atgcaaagcc aaataggccc attcatcttc attgatggta
    54361 tagtttttca aagccggcat gttgctgaaa tgccttttta ctgcgtcaaa gactttggga
    54421 ttttctttct ttatctcctc agtcaatggg ttctcaatgc gaatacctcg gctcaatcga
    54481 atcatcatcg gtgacaaatg atcgagtagt ccattgaaaa gctggagatc ctctactaat
    54541 gaaaaatgaa attcctgaga caatcttttc agaactttcg ctaattcctt tgatagttcc
    54601 tgatcatttt gattttcttt gtgattcgac ttagccatga gatgtaatgt caaataagca
    54661 atttcttctt cgggaaacga tacacctgcg attacctcaa tacgttgaac gatccgctgc
    54721 gccacttgat actctactcg cttagaaact tcttgttcga tgcctaattc cttgatttca
    54781 aacccttctc ggagccgttt gatccccaaa gccaagtgta aagtcagatt ctgtatgata
    54841 aaatccgaaa cttttaactt agcttctctt gtttcatcga gaatgataat gactagctct
    54901 tcaaaactga tgtctgggaa aaaacggctt tgccctaaat attctttcaa tgaatttcca
    54961 taatggtttc caaaaaaagt atccatgata aaatgccgtc gatttctttc ttccccttcg
    55021 atccatgtcc cttgaccatg cttagaaacg atttttagtg aatatggaat caatcgctcc
    55081 ttgatttctt gcatgtcctt tgtcaaactg gaacgactga tataaagctc ttctgccaaa
    55141 tcatccataa aaagaatggc atcttccaaa agcaattggt tcaatatata cttttgtcga
    55201 tcttcggact cataaaatcc ttgcggttct ctagcatatc caggtactat ttcttgccga
    55261 ctcaaaaaca agtcaaatgt cagtctttgt aaaatatgca gttggtagcc ataacctggt
    55321 ttagcaatga tcttacctcc gtttttttct actaactctt tgatccgctg caagtaatta
    55381 cggattgtcc gatcagataa taacaattca gaagctaaac gttgactggt gacatactcc
    55441 ttcttgtgat caatcaaata tctcaacagc aatttttcct tctgtttcat tatcatccac
    55501 tcctattcca tcatatgttc tcttcgatca cctctgctaa cttctggatg cctgtaggga
    55561 ttgggacata cgcttggaaa gggatactaa caacaggctt tccaacagat tctcctaatt
    55621 ttttgaattt atccaaaaac atcgtcgttt gcgggctgat cagaaataaa tcaaaatcac
    55681 tattcttaat catattatcg ccttctgtag ctgaaactgc atctacgagt acctcttctc
    55741 ttttttgctt aaagaaatcc gttgtctttg aggccatcat cgaggatgac attcctgccg
    55801 cacaaataat caatgctttt ttcataaatc aatcactcct tttattttta taaaccaagc
    55861 atatcttgta agcgttttct attcaaaata tatatttccg tagcattgcg gaaaaaatgt
    55921 gtatcatatc ttgaataata atttctggca ccgtgatata ctagtgatag aattttttca
    55981 ggaggggatt tagtgagtat cacagtgaat attttgtata caagtacaaa tggacaagcc
    56041 agaaaatttg cagaagaaat ggtcgaaaga aacattgtca aagcgattcg tgcagaagaa
    56101 ggaaacgaga aatatgacta ttactttcca ctagaagatc cagaatctct tttactgatc
    56161 gaccgttgga aagatgaaga agcaatcgaa aagcatcaca aatccgaaat gatggctcaa
    56221 ataaacgaac tccgtaaaaa gtataaatta aaaatgaaag tcgaacgttt cactgattta
    56281 ccgtaaaaag atacacatgg aatgatagca atttatcatc catgtgtatc ttcacttttt
    56341 ccttattttt tattcgatct catctaatga ttcaaaccgt gtttttctct tatttttcgg
    56401 ataagtattt cagtcacccc aatatacatg attcctaaac ataccccaag gatattctca
    56461 aaaatgcgga tcgttactgc tcctggaacc ccgaataaac tggcagtgat tgccaaagca
    56521 ccaaaagaat taaaaactgt tttatatcta taggtagaac aaacacctaa agctagacca
    56581 cctaatatac cgacccagtt aaaaggaata aattggctga taccaataaa taaaacacat
    56641 ccaatcaatg agccaatgat tcggtctact gctcgttctt tgaaaccaat cgacatcaat
    56701 ccatagctag atacaataga agaaaatgca aaccctgccc acatcaatcg ctgaaaaggg
    56761 acatactctc ctgcaacgat caaaagacta atgccaaatg catagatgag catccaaatt
    56821 ttttcctgcg aatacatgcc tttcaaaaaa atctctttaa acaagctttt gtctttgttc
    56881 ttttctcgat gttttctgta aaggagaact gaaaaccaac aaaaaaacaa aaataataag
    56941 ctacttgttt gtgtaaagaa attcttgttc aacgaatctt taggtaacga ataaacaata
    57001 aagagatatg aaaagccgta caaagaagca ttccccattt tgggatcact agcggttgcc
    57061 attaatatgc tgcttagtaa aataaaatga atcaacatgc ccataactga ccatttgatc
    57121 agctggacat acggtgctac taatagtgag aacatgacga ttgctaaacc tatgatcgaa
    57181 tgggaaatct tataaccaaa gtcaacaaaa cgaatactca tcaacataca gaataaaacc
    57241 acagcgtatg gtttatgctt cgattcaaat aatgttgtaa ttataatgat aaaacaaatg
    57301 gcaaacaata cgatgaataa tgatcgtaaa aacaatgaac aaatatacat gcacttttct
    57361 tttttagaag ctgcttctcg tattttttgt tttaaaataa acggatctag ttgtagagac
    57421 tgataaaaat ccacctgttg tcgtcctttc tttttacttt tattttttac agtcatctat
    57481 gacaggttgt aaatactatg gaacatcata tggcgttgtc attttcttgt caactatttt
    57541 tcctattcat gtttttataa aaaaacatat cgttttcttg tatgattaaa tcaccacaaa
    57601 ataaacaact gagagaacga tatgctttat gaatggttct atcaaaaaaa ttctgagatc
    57661 aatagacaaa aatttgatga ttacagaggt ctcttacgaa accttacaga agaaaaaaac
    57721 attgatcgtt gctgcagttc tcttccctgc tccatgtgtc tgtagaaatt gtggttctgc
    57781 tgtggtagat ggaaatagga aattaatggt ggtgaaaaac aagaagaagg aaaccattgt
    57841 ccactttgaa taatataatc atatgccaat ggttatacgc ctaaaaaagc agcgctatac
    57901 ctgtaaaaac tgtcgaagcc attggaacgc tcaaagttat tttatccgtc caaggcactc
    57961 gatttcaaat catgtcagac ataaaatcac ttctttactg actgaaaaag tgtcgttatt
    58021 ttttatttcg aaaagttgtt aggtatcttt gacaaccgtt attcgcacat tgaaagagtt
    58081 gagaagctat ttaccaaagt cttccaaaag aattctgtct tgagtgttga gggttgtgaa
    58141 tttcgttctc acgtttccgt tgaggataaa ctgagtttta tttccgcgga tggcgagaca
    58201 gaaaaattaa tcgagaaaat ttacctacac aaaaaattcc tcgattaaca aactatttcc
    58261 ttagctgcac taatcctaaa gaaatagaat tcttagttac agacatgaac gccacctact
    58321 ttcagctcac caaacatgtt ctaccaaatg cgaaattggt gattgatcga ttacttggtt
    58381 tttccacgcc tttcaaggag gcgtaacctt tattcacgag ttggttgaag ctttccgaga
    58441 caaaagaccc gacttgtttt tctccttatt gacaaagagc cattaaaact agagaaaaaa
    58501 ttacaactga tcgctgatta tttgtagaaa gaaaatcaaa gtattaccca ataaacttga
    58561 gtcattaggc aaaaaacact gcgaaactca agaatgattt tcgcagtgtt tttgtatatt
    58621 ttttattaac tagtattact acaaaggttt atttttcact tctcaacgca gcacaaaatt
    58681 gtctttactt atttactggt tgggttcaac cttctctact ccgatactaa tatttgtttg
    58741 tatacccctt ctaaaatcgg tagtttccat tcaattgatg ggtactagtt gattttaaaa
    58801 actatgctta ttcaattttt tattttagct catatatttc gtttctttct aaattttata
    58861 ctgatgaaaa caagtagcac acccaatatt gacaatataa actggctaat gatggtttct
    58921 ccagtttttg gaagatgctt atttccactg cttgttggat tgtttcctct tatatctgag
    58981 ctatcagcaa cttttctatt ctcttttgtt aaaaagatcg ccacttcttg ttctttttcg
    59041 atcttgaaag ttactggtgt cgcatccaat tcataccccg ttggcgcttg agtttctacc
    59101 agctgatatg ctcctggtgc taagccatct atcgccagtt ttccatctgc tcctgtggtt
    59161 agacctgact gcagaacggt tccattggca tcttgtaact caaaaacagc tccttgcagg
    59221 acttctccgc tttggtcatc gatctttgtc aacacgacac cgcctggtgt aagtcgattt
    59281 tctttcgtca attctaccac cgctgtctga cttctttcga tctcaaactc gattggtgtc
    59341 gcatccaatt cataccccgt tggcgcttgg gtttctacca gctgatacac tcctggtgct
    59401 aagccgtcaa tcgccagttt tccatctgct cctgtggtta gacctgactg cagaacggtt
    59461 ccattggcat cttgtaactc aaaaacagct ccttgcagga cttccccgct ttggtcatcg
    59521 atctttgtca acacgacacc gcctggtgta agtcggtttg ctttcgtcaa ttctaccacc
    59581 gctgtctgac ttctttcgat ctcaaactcg atcggtgtcg catctaattc atacccc
//
LOCUS       DAXQKX010000012        56385 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.012, whole genome shotgun sequence.
ACCESSION   DAXQKX010000012 DAXQKX010000000
VERSION     DAXQKX010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 56385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56385
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.012"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            330..1175
                     /locus_tag="ACF3MF_000792"
     CDS             330..1175
                     /locus_tag="ACF3MF_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFE3926812.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1456..2676
                     /locus_tag="ACF3MF_000793"
     CDS             1456..2676
                     /locus_tag="ACF3MF_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HFE3926813.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2673..5393
                     /locus_tag="ACF3MF_000794"
     CDS             2673..5393
                     /locus_tag="ACF3MF_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFE3926814.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVCLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5377..6321
                     /locus_tag="ACF3MF_000795"
     CDS             5377..6321
                     /locus_tag="ACF3MF_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFE3926815.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6390..7400)
                     /locus_tag="ACF3MF_000796"
     CDS             complement(6390..7400)
                     /locus_tag="ACF3MF_000796"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFE3926816.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7580..7924)
                     /locus_tag="ACF3MF_000797"
     CDS             complement(7580..7924)
                     /locus_tag="ACF3MF_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFE3926817.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7917..8351)
                     /locus_tag="ACF3MF_000798"
     CDS             complement(7917..8351)
                     /locus_tag="ACF3MF_000798"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HFE3926818.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8489..9226
                     /locus_tag="ACF3MF_000799"
     CDS             8489..9226
                     /locus_tag="ACF3MF_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3926819.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            9219..10430
                     /locus_tag="ACF3MF_000800"
     CDS             9219..10430
                     /locus_tag="ACF3MF_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFE3926820.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10634..11416
                     /locus_tag="ACF3MF_000801"
     CDS             10634..11416
                     /locus_tag="ACF3MF_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HFE3926821.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11486..12148
                     /gene="trmB"
                     /locus_tag="ACF3MF_000802"
     CDS             11486..12148
                     /gene="trmB"
                     /locus_tag="ACF3MF_000802"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HFE3926822.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(12246..14000)
                     /gene="ade"
                     /locus_tag="ACF3MF_000803"
     CDS             complement(12246..14000)
                     /gene="ade"
                     /locus_tag="ACF3MF_000803"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000034 - adenine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006146 - adenine catabolic process
                     [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HFE3926823.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            14132..15061
                     /gene="comGA"
                     /locus_tag="ACF3MF_000804"
     CDS             14132..15061
                     /gene="comGA"
                     /locus_tag="ACF3MF_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HFE3926824.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            15018..16067
                     /gene="comGB"
                     /locus_tag="ACF3MF_000805"
     CDS             15018..16067
                     /gene="comGB"
                     /locus_tag="ACF3MF_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HFE3926825.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            16064..16342
                     /gene="comGC"
                     /locus_tag="ACF3MF_000806"
     CDS             16064..16342
                     /gene="comGC"
                     /locus_tag="ACF3MF_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus major pilin ComGC"
                     /protein_id="HFE3926826.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16317..16787
                     /gene="comGD"
                     /locus_tag="ACF3MF_000807"
     CDS             16317..16787
                     /gene="comGD"
                     /locus_tag="ACF3MF_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HFE3926827.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16759..17106
                     /locus_tag="ACF3MF_000808"
     CDS             16759..17106
                     /locus_tag="ACF3MF_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926828.1"
                     /translation="MVAIQKELNKTGFVLLESLTALMIASVCVYLVSFGQLFLLQAEK
                     KSGEELLFIRMIYEDIKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAI
                     SIEKTSNSSIYAD"
     gene            17069..17494
                     /gene="comGF"
                     /locus_tag="ACF3MF_000809"
     CDS             17069..17494
                     /gene="comGF"
                     /locus_tag="ACF3MF_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HFE3926829.1"
                     /translation="MKKQVIPAFTLIECLIGLMILSSLLLTFNLLIQQTIQVSEFLQR
                     KDQKEWLIFLAQLEEELKSSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQ
                     PMLTSITELQLLEKEHTISFYVHFENGEDGYAIWTKNDQ"
     gene            17466..17825
                     /gene="comGG"
                     /locus_tag="ACF3MF_000810"
     CDS             17466..17825
                     /gene="comGG"
                     /locus_tag="ACF3MF_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HFE3926830.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17997..19004
                     /locus_tag="ACF3MF_000811"
     CDS             17997..19004
                     /locus_tag="ACF3MF_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFE3926831.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLLELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            19029..20213
                     /locus_tag="ACF3MF_000812"
     CDS             19029..20213
                     /locus_tag="ACF3MF_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate/propionate family kinase"
                     /protein_id="HFE3926832.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVDRL
                     RG"
     gene            complement(20650..22233)
                     /gene="abc-f"
                     /locus_tag="ACF3MF_000813"
     CDS             complement(20650..22233)
                     /gene="abc-f"
                     /locus_tag="ACF3MF_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protection-like ABC-F family protein"
                     /protein_id="HFE3926833.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22338..22466)
                     /locus_tag="ACF3MF_000814"
     CDS             complement(22338..22466)
                     /locus_tag="ACF3MF_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926834.1"
                     /translation="MMRMTKITSNENYQRYHIAFSHAIGFTVAVDGTSLSKTVEFT"
     gene            complement(22811..22954)
                     /locus_tag="ACF3MF_000815"
     CDS             complement(22811..22954)
                     /locus_tag="ACF3MF_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HFE3926835.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(23177..23656)
                     /locus_tag="ACF3MF_000816"
     CDS             complement(23177..23656)
                     /locus_tag="ACF3MF_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFE3926836.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23729..24013)
                     /locus_tag="ACF3MF_000817"
     CDS             complement(23729..24013)
                     /locus_tag="ACF3MF_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926837.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(24091..24285)
                     /gene="ssrS"
                     /locus_tag="ACF3MF_000818"
     ncRNA           complement(24091..24285)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="ACF3MF_000818"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24357..25643)
                     /locus_tag="ACF3MF_000819"
     CDS             complement(24357..25643)
                     /locus_tag="ACF3MF_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HFE3926838.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25781..26452
                     /locus_tag="ACF3MF_000820"
     CDS             25781..26452
                     /locus_tag="ACF3MF_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HFE3926839.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26418..26906
                     /locus_tag="ACF3MF_000821"
     CDS             26418..26906
                     /locus_tag="ACF3MF_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HFE3926840.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26919..27866
                     /gene="prmA"
                     /locus_tag="ACF3MF_000822"
     CDS             26919..27866
                     /gene="prmA"
                     /locus_tag="ACF3MF_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HFE3926841.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27867..28631
                     /locus_tag="ACF3MF_000823"
     CDS             27867..28631
                     /locus_tag="ACF3MF_000823"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HFE3926842.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28864..31077
                     /locus_tag="ACF3MF_000824"
     CDS             28864..31077
                     /locus_tag="ACF3MF_000824"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HFE3926843.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            31088..31534
                     /gene="dtd"
                     /locus_tag="ACF3MF_000825"
     CDS             31088..31534
                     /gene="dtd"
                     /locus_tag="ACF3MF_000825"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HFE3926844.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31705..32964
                     /locus_tag="ACF3MF_000826"
     CDS             31705..32964
                     /locus_tag="ACF3MF_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA];
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HFE3926845.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(33053..34000)
                     /locus_tag="ACF3MF_000827"
     CDS             complement(33053..34000)
                     /locus_tag="ACF3MF_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFE3926846.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34394..35686
                     /gene="hisS"
                     /locus_tag="ACF3MF_000828"
     CDS             34394..35686
                     /gene="hisS"
                     /locus_tag="ACF3MF_000828"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HFE3926847.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35701..37470
                     /gene="aspS"
                     /locus_tag="ACF3MF_000829"
     CDS             35701..37470
                     /gene="aspS"
                     /locus_tag="ACF3MF_000829"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HFE3926848.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37579..38454
                     /locus_tag="ACF3MF_000830"
     CDS             37579..38454
                     /locus_tag="ACF3MF_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFE3926849.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38720..40603
                     /locus_tag="ACF3MF_000831"
     CDS             38720..40603
                     /locus_tag="ACF3MF_000831"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFE3926850.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40678..40962)
                     /locus_tag="ACF3MF_000832"
     CDS             complement(40678..40962)
                     /locus_tag="ACF3MF_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFE3926851.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40952..41686)
                     /locus_tag="ACF3MF_000833"
     CDS             complement(40952..41686)
                     /locus_tag="ACF3MF_000833"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HFE3926852.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41815..42438
                     /locus_tag="ACF3MF_000834"
     CDS             41815..42438
                     /locus_tag="ACF3MF_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HFE3926853.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42630..43751
                     /locus_tag="ACF3MF_000835"
     CDS             42630..43751
                     /locus_tag="ACF3MF_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HFE3926854.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43758..46886
                     /locus_tag="ACF3MF_000836"
     CDS             43758..46886
                     /locus_tag="ACF3MF_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFE3926855.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46905..50099
                     /locus_tag="ACF3MF_000837"
     CDS             46905..50099
                     /locus_tag="ACF3MF_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HFE3926856.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(50245..50952)
                     /locus_tag="ACF3MF_000838"
     CDS             complement(50245..50952)
                     /locus_tag="ACF3MF_000838"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFE3926857.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            51717..52115
                     /gene="spxA"
                     /locus_tag="ACF3MF_000839"
     CDS             51717..52115
                     /gene="spxA"
                     /locus_tag="ACF3MF_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SpxA"
                     /protein_id="HFE3926858.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
     gene            52447..53100
                     /locus_tag="ACF3MF_000840"
     CDS             52447..53100
                     /locus_tag="ACF3MF_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HFE3926859.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            53326..54324
                     /locus_tag="ACF3MF_000841"
     CDS             53326..54324
                     /locus_tag="ACF3MF_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA family protein"
                     /protein_id="HFE3926860.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            54500..56308
                     /gene="pepF"
                     /locus_tag="ACF3MF_000842"
     CDS             54500..56308
                     /gene="pepF"
                     /locus_tag="ACF3MF_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HFE3926861.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
BASE COUNT        18553 a         9728 c        11684 g        16420 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt
       61 gaactaatag agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat
      121 agttggttat tataaaatag taatatagct gatttggatt caattcatat ttatttataa
      181 atcaaaaata cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta
      241 cttacttaaa ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc
      301 agtgaattta taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt
      361 tagacggtac tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga
      421 aacatttacc ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta
      481 ataatattct caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg
      541 gatttgatgg agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa
      601 ttgattctgt cctatcgaaa tttccaacca aaatatatac aaatctcgga agttatgaat
      661 ctcagaatta taaaaataaa atgaaaaaaa tttttcacga ggtagggagt gaattttcta
      721 tcaaagagct aaactatgag cttgagtatg aaaaatctat ttgttcaatc ccttataata
      781 atattgagga aattatagaa aaggatgcta tcagcattta caaatttttt atttttattc
      841 ctaatcgtca attgaaagct aatatattta accatttgaa aaagatgcta aatgtgtctg
      901 ttactgaatc ggcacctgta aatattgaaa tcgtacctca aaatgtatct aaaggtgtgg
      961 tgtttgatcg tttggaatca atctacaatt taaagaaacc tttgagaatc gcgatcggag
     1021 atagtttaaa tgacttatct atgtttgaaa gtgcagatat tagttttgca atgggaaata
     1081 gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt ttcaaatgat aaagacggag
     1141 tatctcaagc atttgaaaga attcttacca tataaactaa ttaaggtagt atagaacata
     1201 gaattctaaa tacggaaaaa tggagcataa attccagtac aaatagtact tcttcagtgt
     1261 caaacgaagc gaatataaca tagatattta ggattgtgac aaaaatcatg tcacaatctt
     1321 tttttcgaat aaacttattt tttgaagtcg gccatttatc gtaatttctt tgcataatac
     1381 gaacaaattt tcggttattg atgaaaaaaa acattgaaaa tggtatgata aaagaaaaaa
     1441 aggaggaaat ttttaatggt gaaatttatc catgcggcag atttacatat ggatcggtca
     1501 tttgaaggac tgacaactct tgataaaact gtacaggaaa aactattgaa gacgaatctg
     1561 accgttttat caaatatcat tgaacaggca ataataaata acgttgattt tgttttactt
     1621 gcaggagata attttcatca aaatcgtcct tcattaaaaa tacagaaaca tttttcagaa
     1681 cagatgaaac ggttagaaaa gaaccatata cctgtattta taatattcgg aaatcatgat
     1741 ttctatcaaa aagagcggta ttggttctcc tttcctaaaa atgtccattt atttacatcc
     1801 gaaacggtag agacaaaaaa aataacgata aaaagtggag aaactgtctc tctcagtgga
     1861 tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga tggaatttcc ttctagagaa
     1921 ctcacagatt accatattgg gttgtaccac ggggaacctg gcgtctctca aaaaggaaac
     1981 tatgctcctt tccaaccctc aaagatgcaa gaaaagggat acgattattg ggctttaggg
     2041 catatccatg tgccaacggt cttaaatgaa aagcaaacaa ttgtttatcc aggtgcgcct
     2101 caaggtcata ctaaaaagga acaagcttct acatctattc tactagttga attaagtaaa
     2161 ggaagttgcc aaatacatcc gattaaagta gcagaggtct attggaagac aaaggaaata
     2221 tcattgagga aagcaagaac gacaaaagag gtcattgttc acattcgtca gcagctttca
     2281 aaagtagagg atggatttag tttaattgag ataaaattaa aagattatga ccatctcaat
     2341 acagatgttt tggaacggat acaatcagga gagctattag actatttgtt agaggaattc
     2401 tcagatagga taaatgattt ctttatttgg cgtatttctc tcatagagaa tactttttat
     2461 acgaagaccc cacttgctgc ttctgctaaa ttgatggaac agttatttca atactatcag
     2521 acacctcaag atttccaaca aattttaaat gaagtatata gtcatcaaga agcggctaga
     2581 atattgagcg aactgccgga atatcaagaa gaaacacttg aaaaagccaa gcagctgctt
     2641 aatcaagatt ttttatttga ggaggatcag gaatgaagat tttaaggatc gagattgctg
     2701 cttttggaaa atggcgtcaa aaaagttttg acttttattc aggcaatcag ctgatctatg
     2761 ggggaaacga agcaggaaaa tcaacgattt atcaatttat tcaagcaata ttatttggtt
     2821 tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa agacggctca gcctatggcg
     2881 gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc tgtcgagcgc tacaagcagc
     2941 aaaatcgcgg aaaatcgaag gtgtgcctgg gggatcaagt gggaagtgat gagttactag
     3001 aaaaactgat cgcacctttg acgaaagagt tattccagca ggtatttact ttccagcaag
     3061 agcagttgat ggaactagat catttgagag aaaaagagct acatgatgcg ctgatttctt
     3121 taggcatcac gggcagttct caagtattcc aaaagcggca agaatattat cagaaagcac
     3181 aacaattatt caagaaaaaa ggccaaaaat tactaatcaa tcaaaaatta aatgaatgga
     3241 aagagctgca agaaaaaatt catcaaaaac aagaacagga agcttatttt ggcaagttga
     3301 tccaacaaga acaggaatac gagtcgcaac agcagcagtt attggcacaa ttaaaagagg
     3361 cgaacaaaca attttcatta gccagacagc aagaacttaa tttttcttta tatgaagaat
     3421 ggcaatctct caaaaaaaac agcactacag gtcttcctga tgagcaactt cttttagatc
     3481 tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg tttggaagaa ttagaagcaa
     3541 cactggaaaa gcatagcggg atggatcagc agtcagccag atattatttt tatttagagc
     3601 aggagcagga actaaaagat ctccagcaac ttcaatttac agcggaacaa ttaaacgaag
     3661 aatggcaaag attacaaatt gagactagag aaacaaattc agaattgaag attttggaac
     3721 aaaggtggca ttggcagaaa aatccgttac cggaagaatt tttatatgaa gaagaatgga
     3781 agcatcttct ggctgaagaa agaaggattg ctgatctaga aagccagatt tctgtgcgtc
     3841 tccaaatagc taaagaacag caagagatga ttgaagcaga agtgaatgac ttggaagaga
     3901 cctatccagc attattacaa aatcagtcag agatagcacc agtctcttca tctaaaccgt
     3961 atatgctgat ggctggcgga gcaataatca ttgcaggtat atttgtacca atgcccttga
     4021 aagtgatcct tttactaatt ggtgcaggca tgattggcta tttcttctac aaaaggcaac
     4081 caaaaattaa aactaaaaat gatttctctg agataaaagg aatgtggcaa gaaaaactag
     4141 gacaacttga tctagcctta gctcaattag ctgaagcaga agaaaaacaa aagagaactg
     4201 gagaagaaaa acagattctt cagcaagaag tatatcgttt tgcggatcat cggcacttag
     4261 gaaagatgga tacgctcaaa ctcatgaaag aatatggaca ggaagtcata gattatcaga
     4321 aattatatgg cgtatttgag cggaaacata aaagagaaca ggaaatacaa gaaaaactac
     4381 gacaaatcga ccaaaaattt gagtttgtta aagaatggtt accgatacaa gataagacaa
     4441 tttcagaaaa aatggtattg ctttcccgtt ttatacaaga gatggaacag atgaaatttg
     4501 ccagaagcta tcagcaaaat actttattga agcaagaaat caatcaattg aaaaagaaac
     4561 aaaaagtatg gatacaagaa tacagcgaac aattgactca agcaggctta tcttatcctt
     4621 cggaagtacc tgtcttttta caaaaagcca aacaagccga acagcagatg aaaagataca
     4681 atgaattatc ggaaatgctt actccactat ttcctgaaga gctgacaaaa gagaaattat
     4741 ctgtaagact gcgccaactg aaagaaaagc aatcccaact ccagcaagaa gaaaaagaag
     4801 caagtgaaaa tcggcaacga ctccaacttc aagtagaaga gttgcaaaga gacggcacat
     4861 tggacgaact ttatcaacaa gctagccggc aaaaagcaaa attacaggaa ttactggagg
     4921 aatggggagc acttgaaatc gccgggacat tcttaggtga tctttcaaca gagatgagtg
     4981 aaagacaatt accccagttg ttaagagcag caggtgatta tttaggtatt ttaacaaaag
     5041 gaaattatca gaagatatta ctgaaaaatg atacactgac tttaacagac ggatatacag
     5101 aatttcccat ctatgagtta tctacaggta cgaaagatca gctgattatg gcgatgagat
     5161 ttgcttacct ctcattagaa gctaaccgtt cgatatgccc gatcatcatt gatgatggct
     5221 ggcttcatta tgatcatcag cgaaagtatc aattagctga acttttagct aaatttggag
     5281 aaaagtatca aataatttgt ttttcttctg ataaagaaat ggtaagctat taccatgaga
     5341 tgaaccaaat cgtaaaacaa ttagaaggag caaataatga aaaaaattcg tgatttagta
     5401 atcgatgagc agtttgaaca atttgtcctg atcaaaagtg cagatgtaag aatcgctaaa
     5461 aacggaaaaa aatttattgc ttttactttc caagatactt caggtactat cgatggtaaa
     5521 tactgggatg cttcggagga ggaaatcaat aaatttacag ccggcacagt cgtttttcta
     5581 aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa agattcttca tatgcgctta
     5641 acaagggtag atgagccagg agagcctagt ttatacatgg aaagagcccc tttgaagaaa
     5701 gaagaaatgg aagaagaaat caatcaattg ttgtttgaga tcaccaatgc gcattggaat
     5761 cgtattgttc gctatctact taataaatat caaaaacaat tttttgagtt tccggcagca
     5821 aaaagaaacc atcatgcatt tgccagtgga ttagcttatc atactttgac aatgcttcac
     5881 ttagggaaat caatcgccga tgaatatcct gagctgaatc gagcattgtt gtatgctggt
     5941 atcattttgc atgatttagg aaaggtgatt gaactttccg gtcctatgtc gacagaatat
     6001 acgcttgcag gaaatttgat cggtcatctg gtattgattg acgaagaaat aactaaagcc
     6061 tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc tcgtattacg tcatatggtt
     6121 ttagcacacc atggcttatt agaatatggc tcacctgtac gtccaagaat aatggaagca
     6181 gaaatattac atcaaatcga caatatcgat gcttcgatgc agatgatgtt gacttcgatt
     6241 cgtcaaacag aaccaggaaa atacaccgat cggattttcg gtatggacaa ccgaagtttc
     6301 tatgtaccaa aagatttata gcaaaaattt atttttttca ttcaaaacaa aaaaagcgag
     6361 acataagtct tcgctttttt tgttttcttt tattttgatg aatcagttgt ttcttcagtt
     6421 gaagattctt ttgttgaatc agttgatttt gtgtcagaac tctttgttga agctgtagtt
     6481 tcacttgagt ctttcgtact tgatgaagtt gttgtgaatg cactcaacac attttcaaag
     6541 gcatcatctt tgatttttac atttgcatct tttaattctt caccgattac tttagttgtg
     6601 aatgcattgt cacttagttt agtttcagta gcgatatctt ttagttgatc tttgtattta
     6661 tccatgtcat tgcctttatt ttggtttttc accattttga caacgtagta ttctgtcgca
     6721 taagaagtag gatttgttgt agtaataaca tcggagatct caccgtcttt caatttgaaa
     6781 gctgcttctt ttacttctgc aggaatagtt gttgtcgttg agtcgaattt aactttaccg
     6841 ccatcttctt ttgtctctgt atcagttgat ttgtctttgg ctaatttaga gaaatcatct
     6901 ccatcatccg ctgatttttt cacatctttt gcttcatctt cacttgataa tttgatgatt
     6961 tgtgcttcta cttctggatg gaaagatttc caagcagttt tcaaatcgtc atctgtaata
     7021 tctacgtgag ctttcaagcc agcttcaaaa gctaaattgt tacgaatata ttctttataa
     7081 gtatctttcg tatatccagc agcttctaat tgtgattcaa aagtatcacc taatgatttc
     7141 gcttgtttgt cgtattctgc atccacttgc ttatcggtta ctttatcgcc atatttgtta
     7201 ttgaatactt tataaatgat catccgttgt actaaggatt ggttcgatga ttcaagtttt
     7261 gcttcatcat agaaatcaga tacagtgatc gttccgcctt tcatcgttgc gatatcttta
     7321 ttagtatcgc ctgaacaagc tgctagagtt aaaacagcca acgcactagt agctgccaaa
     7381 ataattgatt tttttttcat taaaatttgc actcctgtaa ttagttatta tttttatata
     7441 ttaactatac catatcccat ttcctttaaa aacgttgtcg tggtagtttc aaacaaaatt
     7501 caaaatttca tcacattcct aggaaatacg caaacttttc tcacttatat agttaaatct
     7561 gttgagaaaa taatcattat tatatttgtt caggatactc tggcagatca gcttttagtt
     7621 tttctacttg ttcattgatt tgtgtgatac gtggttcggc ttggaattta aaatcttcga
     7681 tatctttttt gattgcttct tggaaagcag gaatcacaga ttcagctgtt tcttttgttt
     7741 cgatcaatgc gcttttaaaa tgattcaggc tgttatttaa atcatttgtc agagttgttg
     7801 cttcttccaa ttcttcgatc agtttctttc ttgtttcatt cccgctcctg ggcgccaata
     7861 acagacctcc gacagtgcca gcagcagctc caaataacag tcctttgaaa aagtttttaa
     7921 tcatcgcagg acacctgctt tacgattgtt tcttgaatag cttttagttc ttccgatcca
     7981 taactatctt gatgattgac aaagtgaata gaaaaatcat cctctttgct gtagcgaggg
     8041 actaaatgga tatgtgaatg aaaaacagat tgataggcta gttcacggtt gttattcaag
     8101 atattaagac ctttcatttc tggaaaagct ttttccaatg cttgagcaat cttaggcaca
     8161 cgcgaaaaaa cctctcctgc aagttcggga tcatattcaa aaatatctgc tacatgacgt
     8221 ttaggcacaa ctaatgtgtg tcctttcgtt gcttgagaga tgtctaaaaa agcatagacc
     8281 ttgtcgtctt catatatttt atagcttggg atttcttgat tgatgatttt gcaaaaaata
     8341 cagttttcca tataaaacat cctttctata aagaataaat acttcagctt aactttacca
     8401 taagttaaag ctattgtaag gaaaaaaaca aaataccgtc attttcttcg tggtataata
     8461 aataaaaata aatggcggag gaaaaagaat gagtttaatt atcgatcatg tcacaggggg
     8521 gtacggacat ctccctgtgt taaaagatat cagtttcgat gtacagcctg gagagatagt
     8581 agggttgatt ggactgaacg gagcagggaa aagtacgacc atcaagcaca ttatcggtct
     8641 gctggaagct tcaaaaggaa cgatagaaat caatcatcta tccttaaaga aaaatacgga
     8701 agaatatcgc aaacaaattg ggtatattcc agagactcct tctttatatg aagaattgac
     8761 attgagagaa catatcgaag tcactgcgat ggcctacgat atacctatgg atatagcaat
     8821 gaaaagagca gaaaagttgt tggagacttt tcggttatct aatcgtcttg actggttccc
     8881 agctaatttt tcaaagggaa tgaaacagaa agtgatgatc ttatgcgcct ttttgatcga
     8941 gccttcttta tatatcatcg acgaaccatt tttaggcttg gatccactag ctatcaatgc
     9001 attgcttgaa ttgatggtag aaatgaaaaa agaaggagcc ggtattttga tgtctacgca
     9061 tattttagct actgcagaaa aatattgtga tcgttttgtg gtcttacata acggagagat
     9121 acgagcagac ggttctcttg agatgttgag aaaagaattt cagctgccgg attcttcttt
     9181 ggacgaaatc tatattgctt taacaaagga gcaggcacat gagtagtttt tttcaaaaac
     9241 gtttagcaag acatcaaaag aaaatgatga aatatatgcg ttatgtattg aacgatcatt
     9301 ttgttttagt ttgtcttttc ttgattggcg gtgtgggatt atattattct aattggttga
     9361 aaaccctgca gccaccgttt gcaattggag ggctcataat ctctgtattt tggatgctct
     9421 gtttattcgt gggtaagatg gctacttttg cagaggcagc agatattgtt tttttacttc
     9481 ctaaagaaaa agaaatgcaa acctatttgg aacgagcttt tcgctattct tgcatttttc
     9541 cgttgatctt tttgatattg gcatgcggat tggccatgcc attagtggtg gttagtacgg
     9601 agcaatcctt ttcgatgttt ttcgtctatc tgatcatatt atggagtttg aaattcagtc
     9661 atctgcaaat caagagagca gaattgtttc gactagatca acaagttatt cgttattgga
     9721 aattaggctg gtttttttct tctctgatct ttttgtttct atcattttat tggctaatat
     9781 gggcaggaat agcaggtgca ttagtacagg caagtctata ttactggttt ttgtggaagc
     9841 aacaagaaaa aggattggat tgggagaaaa tggtgcatgt agaagaacat aggttgcatc
     9901 agatctatca atttatcaat ttattcacag atgttcctga aattacggca aagatcaaaa
     9961 gaagacgcta tttggatcct atattgactc atattaaaag agaatcaaaa aacacttatc
    10021 tttacttgtt tgcaagaaga ttggcaagag gttctgattt tagtggtctt tatttccgat
    10081 tagtaattat aggtgggtta ttgattgccg gagtagtcga cttttatttt agtctgatta
    10141 tcggtttctt atttttatat ttgatcggtt tccaactgtt acctttagcg aaccagttcc
    10201 gctatatggt tctcgttcag ctttatccaa tccataagaa tcagaagaag caggcgattc
    10261 agtatctact cacatgggta ttaattatcg cgtcggttat ttttggtttg attgctgcag
    10321 tcgtattaga tgggcagcag cgatgggttc cgctagcggc ttatttgatt gttactatgc
    10381 tctttgttaa actatatgta ccaactcgtt tgaagaagat gtcagactga aaacaaagct
    10441 gtgtagggta aaaatgagaa tgaaaaatag agcgttgaca gtaagaatgc tgttcgttct
    10501 attttttttg agaaaagctg gttttttgaa tggcaattaa atgaaaaaga acgtatatgt
    10561 gcttgacgtg tagtgttcag gcgactagaa taataagtac tgcaaaacaa agagtaagag
    10621 gacgggagaa tgcatgatgg agtttcagtt agaccaagag tggcggttac gtcccatcaa
    10681 aggcgacaca ggaaaaacat acataggcat gcgtgatgag gacaaagtct ttattaaacg
    10741 aaacacgact ccgatgttgg ctgctctttc aagggaagga attacaccaa aacttgtttg
    10801 gacaaaacga acggggaatg gcgatacttt gacagcacaa gagtggctgg aaggtcgctt
    10861 gctgactcct aatgagattg gtcaaagaaa cgacgtgatt gatgttttgt accatttaca
    10921 tcattcaaat tctcttaaaa ccatgctgac ccgtatcggt ggtcgtgtca tgacgccgga
    10981 gaagatgctg caaaaatatg aaaaagaatt accggaagaa ctccagaaaa atcaatttct
    11041 gcaaattgtc catcgttttc ttcgtgagca gatcccgtca atagataagg aaaacttatc
    11101 agtagtacac ggagatgtaa accatcgtaa ttggttagta tgtaaaaatt atttatatct
    11161 agtcgattgg gattcaatca tgtttgcaga ccctgcggtg gatattgcaa cgattttagg
    11221 aaattatgtg ccactgtcta gctggaatca gtggctgatc agttatggca tacgcccgac
    11281 tgacgaaatg cttgaaaaat ttcattggta tgcggccatg aatttgctcc aagaaatcac
    11341 cagatattgc aaacgtgaag atcatcgacg gatgaacgaa gaaattttac aattaaaacg
    11401 aattttcagt ggctgaggtt tggcccaaac tctgcggaga tttggccaga cctttttaat
    11461 tagaggaaag gaatggagat aaataatgcg tgtccgaaat cgtccgggag cagcggaaat
    11521 gttagcggct cacccgaatt ttgtaattag tgatccaaca ttgtggaagg gaaaatggaa
    11581 tgaattgttt gaaaacgatc atccaatcca cattgagatt ggtatgggga aaggccagtt
    11641 catcactgga atggcaaaag cccatcctga aatcaattat attggagtag aaatgcaggt
    11701 cagtgttgtt tcgattgcac tagacaagtt gatcgaacaa ccgcttccta acctgaaact
    11761 tctacatgtg gatggatcag cgttgacaga gtatttcgct gacagcgaag tagatcaaat
    11821 ctatctgaat ttttccgatc catggccaaa aaaacgtcat gaaaaacggc gattgacata
    11881 taagactttt cttgctgtag atgaacagat tcttcgtcca aatggagaaa tccatttcaa
    11941 aacagataat caaggattgt ttgagtattc tctggcaagt ttttctcaat atggcatgat
    12001 cctcaaacag gtatggttag atttacatca aagtcaattt gaaggcaata ttatgacgga
    12061 gtatgaagaa aaattttctt caaaaggtca acgtatttat cgagtagaag ctcaatttca
    12121 agataagacc aaaaagaaaa gtctgtgaaa ctaactttct gctttcataa aaacattaat
    12181 atccataaat aaatcccaga aaatgaacat tacagatgta atgtattttc tgggatttat
    12241 ttgatttaaa atgtatttat ttcatcggtt tttccacaag gtggaatcaa ttggaagcga
    12301 gaaaatgaaa ataatccttt gtcggtgatc ttcaattcgg gtatgacaga taatgttaag
    12361 aaagaaagtg tcaaaaaagg atcaaaggtt ttagctgctc ctagttgatg tgctttagtt
    12421 attaattcat tcaactgttc atagacgatc gaaaaaggtt cctgtgtcat gattccgcct
    12481 ataggaagag aaacacaagc tatttcctgc tgtttgttga caacggtcat cccgccacct
    12541 ttttgaatca aaagattagc agcatacagc atatcctcgt cgtttgtccc aacgacaact
    12601 agattatgcg agtcatgggc aatcgttgtc gctatcgctc cttgtttcag ctgaaatcct
    12661 ttcactatgc ctaatccaat gtttcccgtt tgatggtgac gctcgatcac cgcaatcttt
    12721 aattggtctt tttcgattga aggaatgaat cgttcgcctt gtcggtccac tttttctacc
    12781 aaatctttag tcactagact attcgggata atttcgatca catgggcttg tgaagaagaa
    12841 agaagcagct ctaacgaatg tggatttaat ggttgagcgt ttagttttgg cagacaacac
    12901 gtatatgaat ttgaatgatc agcaaataaa tggtcttgga gttgcccaga ttgaacaact
    12961 aatgttccct tatagaaaac ttcatgaatt ggcagcttgg taagatcgtc tgttaagaag
    13021 aaatcagctt gatacccagg ggcaatcgca cctagtgttt tcaaatcaaa acattctgct
    13081 gcattcaatg ttgccatctg aatggcttgt aatggatcga ttccaagtgc aatagcttga
    13141 cggacgatat gatcgattga tccttctttt actaaatcat tgatcagttt atcatcggtg
    13201 acaaagaagc atcttcttga attttcaggt gtgatcgccg gtagtagcga tgccagatct
    13261 tttgcaacgg tcccttctcg aaccattaaa tacataccaa gatccaaacg ttctttagct
    13321 tcttttgcag ttgtagcttc atgatccgtc cgaatacctg ctgcaggata aacatttaac
    13381 tcttccatgc cgataccagc tgcatgcccg tcaatttttt tcttatgctg gtgcatcaat
    13441 tggatctttt ctaggatgtc tgtttcatta tttgctactg cttgatagtt catgacttca
    13501 gctaagccta aaacttcggg tttttgtaaa aaaggggcta atttttttgc atttaaattt
    13561 gcaccattgg tctcaaaagg ggttacaggt acacaagaag gtagcataaa aaagatattc
    13621 atgagtgttt gtcttgcatc ttctatcata aactcaagac ctgtactccc agcaatgttt
    13681 cctatttcat ggggatctgt cactacagta gtaactccat gaagcaagga tacttttgaa
    13741 aattcgcttg gtgataaaag tgagctttcg atatgcacat ggccatcgat gaatcctggc
    13801 actagatatt gcccattagc attatgtacg ctttttcctt cgtattcacc gattcctacg
    13861 atcattcctt cgcagattgc tacatctttt tccatgattt ctttcgtaaa gacgttgacg
    13921 atcttagcat gcttgatcac taggtcagca ggcttttttt tacttgctac ttcgatatat
    13981 ttccttaatg ttgtttccaa tggagtgcct cccaagataa atttttataa gtataacata
    14041 aattcggttt ttgccaatat ttttttgtaa attcatttta tttgaaacaa aaagatcaaa
    14101 aagacgtatg ttttttgtgg aggggagaat aatggaaata aaacgattat cggatcaaat
    14161 gataagtgaa agttttgcca aacatgccca agacgtatat atattgccag cttcagaagt
    14221 attttacatc tattttcgct atggaaaaaa acgaacattc tggaagaaag tctcttcggc
    14281 agatggacag caactgatct caagatttaa gtatttggga cagatggata tcggagaaaa
    14341 aagaaaagct cagttaggtg catttactta ttctttagaa aaacaggaag ttcgtctgcg
    14401 gttgtcttct gtaggagatt accttcaacg agagagttta gtgattcggc tattatacgg
    14461 tacttttgaa acaccccatc gttgctttag ttctcgagat tttgcaacta ttttacagaa
    14521 aaccgtcaga cgtggattat accttttcag cggaccagtc ggatcaggca agacttctct
    14581 aatgtatcgg ttggctttgg aagaaaaatt gcaagtgatt actatcgaag atcctgtaga
    14641 gatagaagaa ccgttttttc tgcagctaca gatcaatccg aaaatagcac agacttatga
    14701 tacacttttg agactcgcat tacggcatcg tccagacttg ctaatcattg gcgagataag
    14761 agatgaatca actgcacatg ctgcggtaag agcagcacta acagggcacc gggtttttgc
    14821 aaccgtacat gcacgcaatc ttgaaggtac attggtcaga atccatgaac tgacaaagaa
    14881 aaaagaagag ctatctgaat gtttagctgg tgtcatttat caagaacttt tggaagatgc
    14941 caatcaccat ccttctgttt tatggagtta tcaatttatg gaggaagaat cagtaaaaaa
    15001 atcatgggag gaaagttatg aagaagctca ggaaaatatt tggcagtcag aactattcta
    15061 aaggattaac aagaagccag caaaaccagt ttgcacaaac catgggagaa ctgcttttat
    15121 ctggttttag tctgcaagaa tccctttatt tattactcac gatccgttcg tttccacctg
    15181 ttattttggc aaatatccaa catcagctaa aggaagggca agcgtttagt gaggtacttt
    15241 cgcaaatagg atatggagca gagcaactgg tacagatcga gttagctgaa cgtcatggga
    15301 atctgccgac aactttgttg gaaattgcca aacagtttcg gcttgttgaa ggatttcgca
    15361 atgatttgaa aaagctgctt gcatatccga tgctattgct cacctttttg ctaggtatct
    15421 tgtttagtat gcggttgttc gttttgcctc agcttattgg ttcaggaatg gtcatgcaag
    15481 agcattgggg tattcagctg atacaagtct ttcattggta tgttctacta ttcatcctag
    15541 cggttactct attggcttta ctagtaaggt atcgtctgat gaagttgtct cctgttgatc
    15601 agagtgaatg gataagcaga caattattga ttggaccgat atattccttg tatcaatcgg
    15661 cttatttgtc actagagatt ggaaagcttt ttcatgaagg tttcgaatta aggcaaatca
    15721 tagtctgctt aaaggaaacg aaacaagaaa gtctgattca gcatcttgcc tctaagttga
    15781 ttcaaggatt ggaggcaggt atgtcattgg ctgagcagtt ccagaattat cgttttctat
    15841 cagaagaatt cagtaaaatt gttttacagg gagaggcaaa gggaagttta ggtaaagaac
    15901 tgatttttta cagcgaatgg acaagaaaac agcttttcaa acgtcttcat cactggatgc
    15961 attttattca gccaatcatt tttttgggcg tagcggcttt gattttatta gtttatgccg
    16021 ctgttttatt acctgtttac ggaagcatag aggaggtttt gccatgaaaa agagaaaaat
    16081 atcttattat agcggtttta cattgatcga aatgctaatc gtcttactga tcatcagtgt
    16141 attagtgttg ttgttcgtcc ctaatttgtc gcgttatagg aatcatgtag accaagaaag
    16201 tcgtgaagcg atcatccagt tggtagacac acaaaaagag ctctatgcgc ttcaaaataa
    16261 tggaagagtt cctactgtgg aggaattgtt gaatgaaggc tatatcaaac gagaacatgc
    16321 agaaatctat cagcggcctt gaaggtaagg ttttagcatc aggatatacg ttgtttgaat
    16381 cactcttact gattttatta cttacaacga tcctttcttt tccagttctc gcattttctg
    16441 catggaagaa tgaattggca gtctatcaat ttttcggcca atttgaaaaa cgaatctatt
    16501 ctacgcaaaa aatcgctatt gtgaatcaga tccaaacagg cttttattgg aatagtgaag
    16561 agaatcaaat catttttcat gttccgaatc cagataaaat aaattgggaa gtattagata
    16621 ttcctgatga gattaccttg aaacgccatg cttctattac ttttgctgct agaaccggga
    16681 atgaaagttc actaaaagct tatcaatttt attgggaaga aaaagagcgg acgattacgt
    16741 atcaattcca gatagggagt ggtcgctata caaaaagaat tgaataaaac aggatttgtt
    16801 ttgttggagt cccttacagc gcttatgatc gcttctgtct gtgtctactt agtgagcttt
    16861 ggccagctgt ttttgcttca ggcagaaaag aaaagtgggg aggaactgct atttattcga
    16921 atgatttatg aagatatcaa gacgcagcgg atgtatcaca aaagaccaga gcgaagggaa
    16981 gaaatgatcc catacgatat ccaaattgtc gataataatg gagtaatcga aaaagtgttt
    17041 gtcaatatgg agaaagaagc gatcagtatt gaaaaaacaa gtaattccag catttacgct
    17101 gattgaatgt ctaattggac tgatgatatt gagcagtcta ttgctcacat tcaatctttt
    17161 gattcagcaa accatccaag taagtgaatt tttgcagcgt aaagatcaaa aagagtggct
    17221 aatattttta gcacaattag aagaagaact caagagcagt cacaatgtct ctgtgaaaaa
    17281 tcagcaactg cactacacga tcgaggataa acagtatatc atcgaaagat atcaggcaat
    17341 gatacgtaaa agaagaactt ccggcggaca tcaacctatg ttaacaagta tcactgagct
    17401 tcaattattg gaaaaagaac acacaatttc tttttatgta cactttgaaa atggagaaga
    17461 tggatatgcc atatggacaa aaaacgatca gtagaaaatg ttataagggc tctattttat
    17521 tttctgtctt gcttttattt cttttatgta cgtttttatt gatggcagca ttagaaagct
    17581 accgtttgtc aatggatctt aatatacgaa tcaaaaatta ttatatagca aaaataatga
    17641 agcagatggc tttatcggaa cagtctacgc ttgccgaaag ttcggaagga gttttttact
    17701 acacaactgg atctgtaaca tatcagtggg tacaacagtc cctattctta gaggtggaag
    17761 tctcaccgtt tatctttcgg ttcacagaag aagtaaaaaa tgatacagat actagtacag
    17821 aatgatggaa tgttcgtgaa aacgccctct tttctgttat aacactgttt ttaataaaaa
    17881 aatgtttgcc gtttcacaaa taaaaaacag tgaaaacgat tgaaattttg tcaattgttc
    17941 gatagaatta aacaggtgaa aaaattgtta taatatatct agaaatgagg tgcaccatgt
    18001 taccagaaaa aatggaacaa gggtttaatc aaaacctgga agctattcag cttttacaga
    18061 atgcattggg aacttccttt ttagaagcct atgtcgaaaa tgcagaaaat ttaatagatg
    18121 attatcaagt acgtgtggtg gatggagtgc cgacaaaaga gacaacgcaa cggatcacag
    18181 ctctttatga agagttgaag aaactttctt tcgagccaga agaatggcgc agactgtctc
    18241 aattactttt attgaagggc agccagacag aacatttgca ggcgaaccat caactcactc
    18301 ctgatagtat cggtttttta tttgtttttc ttattgaaca actatacaca aataaaaaag
    18361 caccggttaa gattctggat attgcggcag gaatgggcaa cttgttatta acagttcttt
    18421 taaacctatc gaatgcgggg taccaaacag aaggaattgg tgtggatatt gatgatacat
    18481 tgttggctgt cgcagcttct acaagtgatt tgacacaagc aaatgttcaa tactttcatc
    18541 aagacgggtt gctggaatta ttaatagatc ctgtcgattt tgcaatcagc gatttgccaa
    18601 tcggttatta tccgaatgac gaaaaagcaa aagagttttt aacaagtacc gaagaaggcc
    18661 atagttatgc acatcattta ttgctagagc aatcaatgaa atatgtgaag ccggatggtt
    18721 ttggtttgtt tttgatgccg agtggatttt tagaaacgga tcaaagtgaa gaaatcaaaa
    18781 aatggtttaa agaagaaggt tatcttcaag gaatgattca attgccagat gaattgttcc
    18841 gtaataaaca atcgcaaaaa agtattttga tcttacagaa aaaaggacca caagcacaac
    18901 aagtaaaaga agtcttgctt gtgaaacttg cttcattaaa agaaccagag aaggtgacgg
    18961 aatttttcaa cgagtttaaa aactggaaat catctgctct gtaatcattc aacgagaagg
    19021 agagtcatat gtctaaaaca attgcaatca atgctgggag ttcaagtttg aaatggcaat
    19081 tatatcaaat gccagaagaa accgtagttg cgaaagggat cgtcgaacgt atcggtttac
    19141 aagattctat ttttaccatc aagtacggcg ataatcaaaa attcgaacaa atcatggata
    19201 tcgaaaacca cgaagtagca gtaaaaatgc tgttagatca gttgattgaa ctgcaaattt
    19261 taagctctta tgatgaaatc accggagtag ggcaccgtgt tgttcacgga ggagaaactt
    19321 atggggattc agtagtgatc gatgagaaag taatggaccg cattgctgaa ttagcagaat
    19381 ttgctccttt gcataatcct gcaaacttaa tggggatcaa agcgtttaaa aagattttac
    19441 ctgacatttt gagtgtggct gtattcgata catctttcca ctcaacaatg ccaaagcaaa
    19501 attatttata tagcttaccg gtgtcttatt atgaagattt caaagtaaga aaatatggct
    19561 tccatggcac aagtcatcgt tatgtgtcgg aacgtgcggc aaaattattg aacaaaccga
    19621 tcgaagaact aaaaatcatc acttgccact taggaaatgg tgtatcgatc acagcagtcg
    19681 atggaggtaa atccatggat acttctatgg gattcacacc attagctggg gtgacaatgg
    19741 gtacacgttc aggtgatatc gatccagctg ttctcccata tttaatggaa aaattagaga
    19801 ttgatattga tgaaatgatc aatgttttga acaagaaatc tggtctgcta ggcctaacag
    19861 gattgtctag tgatatgcgt gatcttgaaa agaactatga aaaagaacat attcgtttag
    19921 cttatgacat tttcgtggac cgcatccgaa aatacatcgg cggttatgtg acaacgatga
    19981 atggtgttga tgcaattgtc tttactgctg gtatcggcga gaatgacgga catgtacgta
    20041 gtgaaatcat caaaggtatg tcttggtttg gttgtgaaat cgatccagcg ttgaatgaat
    20101 tgcgtggtga agaagtagat atctctacaa aagaatcaaa agtaagagta ttagtgatcc
    20161 caacagatga ggaactaatg attgcccgtg atgtggatcg tctgcgcggc taagccaaag
    20221 cattcgttag gataaaagat gaaacgcatg caagagggaa ttcttgcatg tgtttttttt
    20281 gcggagaaga ccgcaaaatg gtaatttaac ttcaatttcc cttctttttt acaggatctt
    20341 cttagggaat tttgcttgga aaagtggtca aaagggaaaa gactggcatt ttatttattg
    20401 attttcagga aaatcccaat attttatttt cattcatctt tataagggac attacatatg
    20461 taaaaagaaa aaacattttt agatcagcct cgtgggctgt cgactttatt cttcgcttta
    20521 tgtttagcta gaaaaccgat ccgaaacatt cattgatcga ataataaaaa cttgattttc
    20581 cacctgtact ttgcctgaat cgtgaaagca caggtatgaa aatcaagttt tttgttgcga
    20641 aaaaacgtcc tagtcaatca gttggccgag cggctggcgg ctgatctgct cctgatcaat
    20701 aacgagtgct tcttggaagt gttgctgcaa aaagtagcgg tcatggctga ctgctaggag
    20761 cgttccttga tagtcttgca gcatttcttc aatttcttct cgagcatagc tgtcgaggtg
    20821 attggttggt tcatccaaaa tcaggacgtt gattttttct aaaaagagtt tcagcaacgc
    20881 caaacggatt ttttcaccac cggataaatc tttgatccgt ttacccacat cgctttgata
    20941 aaagccactt ttggctaatt gccgtcgagc gacttcttcg tttccagtca atgtgatggc
    21001 gtaagccagc aaacggctat cgggatcggc aaactgcagc tgctgcggca aataaccgat
    21061 ttgcaagcta ctacctaatt tgatggtgcc accgtaaggc ttttcctcac cgagtaataa
    21121 tttgagtaag gttgattttc ctgcaccatt gtcgccgatg atggctaaat gatctccacg
    21181 atagactgca aaactgctgt ctttgaatag tacttgatca gcgtactgct ggtgcaagtt
    21241 ttgaatgatg aaaacttctt tgccagattt tccaccatta gacaagcttt gcagccgatt
    21301 tttcggggga ggtggcggtt tgacgagtgt cagtttcgcc aggcggcgtt ccagttcttt
    21361 ggcttttttg aagaaggact cattgtctcc ttcatgtgcc cactgacgaa aacgacgaat
    21421 catgactttc aaccgctgga cttctttttg ctgcagttcg taattttttg tcagctcagc
    21481 caagcgagct tctttcaaga ctcgaaaacg gctgtagttt ccgggatact caatcaatgc
    21541 accttcttcc agttcccatg tttttgtggt gacttgatcg agaaattgcc gatcatgaga
    21601 aacgaccaga accgattttt ttgtattctg taaatagttt tccaaccagc gaatactgtt
    21661 aagatctaaa tgattggtcg gttcatcgag taaaagtaaa tcggcatcgg ctgctaaaat
    21721 tttggctaaa gcgactttaa ctcgttcgcc tccgctaagt tctgttaacc gtgcttcctg
    21781 acggtgtgga atccctaagc cttgcaagat cgctgcaatc cggtcttcta atacgtaacc
    21841 gcctagttct tcaaagcgat gctgcagctc accgtaacgg gccagacact tctctaagtt
    21901 tgtatctggt tctgtcatca atgcttcgta gcgactcatt tgctgtttga ggtcctgtat
    21961 ctcagcggca gaatggagca agtagtggtt gacggtcgct tcggaaactg taagttcttg
    22021 ttcgaccgtc ccgatcttta agcctttttt gcgactgata acaccgctgt cgacaccttc
    22081 tctgccggtc aagatttgta aaaaggttga tttgccagtt ccgttgatac cgactaaggc
    22141 aattttttca ccagcttcaa tttgacagga taaatcctca aataatggat tcccgccgat
    22201 tgttttttta atagaaattg cttgtatgat catgatctct ctccttgaga ccactcaaaa
    22261 aggccatggt tatccatggc ctgtgttatt taaactcaga ttatcatgag aaaaatacct
    22321 tgagatggcc attgatttta cgtgaattca actgttttgg acaaacttgt cccgtcaaca
    22381 gcaactgtaa aaccaattgc atggctaaat gcgatatggt atcgttggta attttcatta
    22441 cttgttattt tagtcatgcg catcatagta ttttccctcc ttcgtgtagt tgtcttttcc
    22501 agtgtacctg aaagtgtcag aaagttcaac tagcgctgac atttacttaa tatttatcga
    22561 tgtgtaattc tgtcagagag ctttttttat ctgactgagg gtaatgtctc gtggaccaca
    22621 tcattgtatt ctgagctaaa ccagcgttca ggcgaaatca tatggtgttt gataaaaaac
    22681 tttgtctaca tgacttcctt ttgccatttg cttaataccg ttgcattaaa cagctcttct
    22741 ctttggaaat ctcaccaaca tcgcgttcag gagtatcgtt gtggttgcaa tggcaagcgg
    22801 tagcctttca tcaattcttg aatgatttac cgaatgtagc acttgccttc tcgcggtacc
    22861 cgaacccgaa ataaaatttt agtttggcga taaaatcggt atccgccatc gatacttcat
    22921 attttttcgt atcagattca tcggaaactt ccacattgac gaaccaataa gctttggcat
    22981 gcttaggtcg ttttaaacca caccagggcg actaatcgcc ctggtgttca ctttttttta
    23041 ttttacttga actcattgac tgttttccct ttattttaaa cattataaag accgatgagt
    23101 gcttgccgcg tcttttgttt ttatcacggt tttttgtgca aaaaaacctg ccgatagttg
    23161 gcaggtcgtc tacgtgttaa gctttggtgt ggtctttagc tggcaattgg ttttctaaat
    23221 cagttcggac aacaagcaca tcgcaagctg cgtttctaat aacatattca gaaacagaac
    23281 caataaataa acgttctaca gcattcaatc ctgtggctcc taacataatc aaatctactt
    23341 gattatcttc tgggatttct ctggcaataa tttgttttgg tgagccatat tctacgacag
    23401 aggttacatt attcaagcca gctttcttcg cattgctttc ataatctgcc aatgtttgct
    23461 ttgccatttc agtagcttgt tctgcaagca ttccatcaaa ggatgaaacg gtttggaaag
    23521 aacgtgtgtc aatgacatgt gctaatagaa gttctccgtt atttcggata gctacattga
    23581 ccgccttttt aaaagctaat tcagcttcat cagaaccatc tacggcaacc atgatttttt
    23641 tgtattgttg taacataagc attcactcct caagtcaatc gtattgtact cttttattgt
    23701 agaacacttt agggaaaaag agaattattt actgctttgg ttcagcaatt ttttttgcaa
    23761 atcggatact gaaggtggca gaaacaataa ttacgatcag taaaaagacc aaggcaataa
    23821 agcgttgatt gaaaaaagct gttaaaatac ccattacgcc taaaacagca tatgcagctc
    23881 cgtaaaattg taggaatcct tgatttttat catttttgtt gatcaataca aaaaagatat
    23941 cctgtttatt aaataaataa tagctaacga ataataatac taaagtggcg ataatcatta
    24001 aaatcctaat catgaacaaa tcctccaaaa taagcaacaa atagaaaaag caatttgcca
    24061 agagcaaatt gctttattct ttaaaagatg gtaatctccg ttaatgccgt tgtttgtcct
    24121 gtagtattga tcccgcgaat tcaagcaggt gggtcccatg gtcgtagctt cgaactacca
    24181 aatgataagg catgttacca gcagtgacac aagacgggtc ccaagatatc aataaaaatg
    24241 ttcggtcaac acacaaagag gacaattcga acatcacaga tttcccacct ctatagtagc
    24301 atatgaattt aaaaagagca atgagagagc tcgcagaaac agaaccgttt tcttgtctag
    24361 ttttttggag gatgcttttt ccactctttt atacggtaat actgttgacc cagagcctgt
    24421 tcatatttcc ctgtatcttt tggctgataa tactgagcat tcttcagttt atctggtaaa
    24481 tattgctgat tgacccaagc ctgatcaaaa tgatgaggat actgataacc cacgccacgg
    24541 ttgagtgatt tcgcaccttt gtaatggcta tctctcaaat gatcaggaac atctccagct
    24601 ttgccctctc gaatatcagc aagtgctgca tctaatgcca tgtaggcaga attggatttt
    24661 ggcgacaagc aaagatcgac gacgacgtct gctagtggga tacgtgcctc aggcaatccc
    24721 aatttttcag cagctaatac agcgttcact gtacgagccg cagcagcagg attacctaaa
    24781 cctatatctt cataaccgat aaccatcaga cgccggcaaa tacttgccag atcacctgcc
    24841 tcaactaaac gggcgagata atgaagtgca gcatccacat cacttccacg aatcgatttt
    24901 tgaaaagccg aaataacgtc ataatgagca tctccatttt tgtcatgggt aagagctttt
    24961 ctttggacac attcttcaat gatcgacagt gtaagatgaa tccttccttc tttatctgaa
    25021 ggagtcgata gtgtagccag ttccagccca ttcaatgcac tccgcaaatc gccgttcgtt
    25081 gcacgcgaaa ggtgaagaag agcatcttcg tctaactgga ttgcttgttg tccaaggccg
    25141 cgttctttat cccttaaagc atgttcgact gccaactgga tgtcttgttc tgttaatggt
    25201 ttgacttcaa agatctgtgt acggctgcgg atcgctggat tgatggtaat ataaggattc
    25261 tcagtagtcg ctccgatcaa gatgattcgg ccactttcta aatgaggaag cagaaaatcc
    25321 tgttttgttt tatctaatcg gtgtacttca tccaataaga ggatcactgt accactcatt
    25381 tttgcttctt ccgctacaac ttgtagatcc ttttttgaat ctgtagcggc gtttagcatg
    25441 cgaaatgcat aattagtaga gccggcgatc gcacttgcga tactcgtttt tccagtacca
    25501 ggaggtccat atagaatcat ggaagagagc atgcgagcat cgaccatgcg gcgtatgatt
    25561 tttccttccc cgactagatg ctgctgacca acgacttcat cgatcgttcg aggtctcatg
    25621 cgataagcca atggctgttg cataggattt tcctccttct tgtttttacg tcccttaatt
    25681 atatcatatt tagcaagatg cctagaaaga acagccttct gttgttttgt tttcatagct
    25741 tatccaacta atattgtgta tgataaagta ggtgagaaaa atgacggata aacaaaagat
    25801 agatgaattt ttttggaata aaacgacgcc agaagtggca cgggatttat tggggatgta
    25861 tttggagcat gacacaccag aaggaagatt agctggatat attgtagacg cggaagcata
    25921 cctaggtcca gaagacgagg ccgcccatag ctatggttta agaagaacac cgcgtgtgcg
    25981 ggcaatgtat gaaaaaccag gtacgatcta cctttacacg atgcatactc atcggatttt
    26041 gaacatcatt actcagccag aagggattcc tcaaggagta atgatacgtg caatcgaacc
    26101 cgccgcaatg attgatcaaa tgagtaaaaa tcgtggcgga aaaactggtc cagatatcag
    26161 caacggtccg ggaaaattag tggaagcatt agcaattcct caagaacttt atggtcagtc
    26221 tatagcagat agttcgttac gcttagtttt tgagaaaaaa aagacaccaa aaaagatcaa
    26281 tgctttgcct agaatcggta tcccaaacaa aggtgtatgg acagaaaagc cgttgcgttt
    26341 tgttgtgtcg ggaaatcctt atatctcttt acaaagaaaa aaccaaatcg agaaagattg
    26401 gggttggagg aaagaaaatg aaaaagaagg atctattaac atatttagat gaaataattg
    26461 aaaaacaagt gacagactat gatgtagctt tagattggga tacaaaaaat catacgatcg
    26521 agatcgttgt tcgcttgttt gcagaaaata aagcacaatt tgagattgat gatgcagaag
    26581 ggatcgtttc gcaagaacca attatcgaat ttgaagacgg cgtacttctt tttaatcctc
    26641 agaaatctgt ttttgatgaa cgcaattatc tagcagtaat cccttatgaa ggaaaaaaag
    26701 ggttggcaaa atcagtagct gattctttag tggaatatct aaatgaagta ttagctcaag
    26761 ggcaaagcga tttgcttgat tttttggatg aagacgatga cgaagctgta ttcgagcttc
    26821 actgggataa tcagcaacta gcagaattag tagaagtaaa acagcaaaat gaagcagata
    26881 cttatttacc gtacccaagt tattaaggag tgacagatat gaaatggaat gaagtaaaag
    26941 tagaaactga aagtgaagca gtcgaagcag ttgctaatat tttgatggag gcaggggcga
    27001 gtggtgtcgc gattgaagat tctttagatg ttgaacattt tcagtcggat caatatggtg
    27061 agattttaga taaaaatgat tttacatcgc tgaaagaagg cgcactagtc atggcttatt
    27121 ttccggaaac gactttctta ccggaaatct tgccttttat caaagatcgt atcacacaat
    27181 tacctgagtt tggtctagct attggaaaaa ataaagtaac agttagtgaa gtagaggaaa
    27241 gcaactgggc aacagcctgg aagaaatact atcatccggt gcgtattacg cgaatgctga
    27301 cggttgcgcc aagctgggaa aactaccaga cagaagatcc tctagaaaaa attatcacac
    27361 tagatcctgg tatggcattt ggcacaggca ctcatcccac gacttccttg acattgacag
    27421 cactagaaac agtcttgcgt ggtggtgaaa cattgctaga tgtgggaact gggtcgggcg
    27481 tgctaagtat tgcagcaaaa tatcttggtg caaaagatgt ctatgccttt gatttagacg
    27541 aagtagccgt tcgttcggcg aaagaaaata tggatatgaa tgaaatagcc aaagatgtcc
    27601 atgtatcagc taacgatctt ttgacaggaa tcgagattga aagtgatgta atcgttgcga
    27661 acattttagc agatatcatc ttattgatga tcccagatgc ttggcgttta ctgaagcaaa
    27721 caggcacgct gatcgtttca ggaatcattg aagagaagaa gcaaatggtt ctggatgcca
    27781 tgttagaaca agggtttatc gtggatcaaa ttttccagca aaaagactgg tatgcaatta
    27841 ttttgaaaaa accagaggtg gaatagatgc agcggtattt tttaaaagaa tcatatgaat
    27901 caaaagacta ttttgtttta gaaggggaaa actatcacca cattgtacgg gttatgagga
    27961 tggaacccga ggatgaagtt tttttggcat tcaatgatca aatagccatt gttgcagaaa
    28021 tcacggagat tactgaagag gctgtttatc tgaaagaaat taaaaaagaa gaaaatcaaa
    28081 aggaactgcc aagttcgatt accatagcga gtggctatcc taaaggggaa aagctggatt
    28141 ggatcgttca gaaatccact gaattaggag cgcaagcttt tcttggtttc ccggcatcag
    28201 cctctgtcgt taaatgggat gcaaaaaaac gtatgaaacg acaacaacgg cttgaaaaga
    28261 ttgctcaaga ggcagcggaa caatcccatc ggcagatcgt gccatcagta gagttattgg
    28321 aaacgaaaca agatttattt gagcggctag atgattatga cgtggtcttg gttgcttatg
    28381 aggaatcagc aaagcaaggc gaaaaatcaa atgcagccaa aattcttagt gaaacaaaac
    28441 cagatagtcg aatcttagct gtctttggac cagaaggtgg attatcccgc gatgaagtcg
    28501 attattttgt agaacacaaa gggatacttt gtggattagg accaagaatc cttcgtacag
    28561 aaacagcacc tctttattta ttaagtgctg ctagctatca atgggaatta atgaatcctt
    28621 ctttcagcta acgttcttca ttaataaaag agtatcgaca gaaagaattg aaaaaatagt
    28681 caacaatttg tataatagaa acaattattt atacaatgga tacgaaaaat cgtttgaaaa
    28741 agcttttaaa aagcgaacat ttccgtaaaa aaacgtataa ctgcacggat tttgggacaa
    28801 ttatcaaaca gatatttgtc ccgattcccg ttttaccgaa aaaagaaagg gggatcgatt
    28861 cctgtgacaa aagaagaaat tttaacggga cccggtgtca taaagctcgt tagtcaatac
    28921 atgggtcccg aacatgtagc atttgttgag aaagcatgcg aatacgcgac tgctgcacat
    28981 gacggacagt ttagaaaatc aggcgaaccc tacattattc atcctatcca agtcgcaggt
    29041 atattagcag atttaaaaat ggatccccat acagtggcta caggcttctt acatgatgtt
    29101 gttgaagata cagaaatcac tttagaagat ctgagagaag aatttggcga tgacgttgct
    29161 atgttagtgg acggcgtaac caaattaggg aaaataaaat ataaatccca cgaagagcag
    29221 ctagcagaaa accaccgaaa gatgctgcta gcaatggctc aagatttacg agttatcatg
    29281 gtcaaattag ctgatagact acataacatg cgtacgttga agcacctgcg agaagataag
    29341 caaagaagga tcgctcagga aactttagaa atctatgcgc ctcttgcaca tcgtctaggg
    29401 atcagccgga tcaaatggga attagaagat acagcacttc gttatctaaa tccaaaacag
    29461 tattaccgta tcgttcactt gatgcagacg aagagagaag aacgtgaaaa atacgtaagt
    29521 ggtactgttg aagatattcg aatagcgaca gaagagctgg ggatttttgc agaaatctat
    29581 ggacggccaa aacacattta ttcaatctat cgtaaaatga aagatcagaa aaagcagttc
    29641 aacgaaattt atgacttgct agctattcga gtgatcgtag attcaatcaa ggattgttat
    29701 gctgtattag gagcaatcca cacaaaatgg aaaccaatgc ccggcagatt taaggattat
    29761 attgccatgc caaaagctaa tatgtaccaa tctttgcata ctaccgtgat cggtccggca
    29821 ggaaatccgg tagaaattca aatccgaaca caggaaatgc atgaaatcgc tgaattcggg
    29881 gttgctgcac actgggccta taaagaagga aaaaatgaaa aagtagaacc agatggtatg
    29941 acgaaacaat taagctggtt ccatgagata ctcgaacttc aagacgaaag ctatgatgct
    30001 tctgaattta tggaaggcgt aaaaggagat atctttagtg ataaagtcta cgtcttcaca
    30061 ccaaaaggag acgttactga gttaccaaaa ggatccggac cattggactt tgcatacagt
    30121 atccatacag atatcggtaa caaaaccact ggtgcaaaag taaatggcaa aatggtgcag
    30181 cttgattaca aattgaaaaa cggagatatc attgagatca tgacttctcc aaattcattt
    30241 ggcccaagtc gcgactggtt gaaattagtt gctactagca aagcaagaaa taagatcaaa
    30301 cgtttcttca aagcccaaga tcgagaagaa aatgtgatca aaggccacga atccgtggtc
    30361 aaatgtatta cagatctagg atttacgcct aaagatattt tgacgaagaa caaactgcaa
    30421 gaagcactcg atcgttttaa ttatcaaaca gaagatgatc tctatgcagc tgtagggtat
    30481 ggagaagtta gccccttgac gatggccaat cgtctgactg aaaaagaacg taaagaacaa
    30541 aaaatcgagc agcaaaagca agaagcagaa gaaatcatga atcagccgaa aaaagaacct
    30601 gacaaaatga aagtacgtca tgaaggtggc gttgtcattc aaggggtaga aaacttacta
    30661 attcgtatca gtcgctgctg taatccgatt cctggtgatg atatcgttgg ttatatcact
    30721 aaaggcagag ggatatccat tcatcgtcga gattgtccga atgttcagcc tgacaaacca
    30781 aatgtagcag aacgtttgat tgaagtcgaa tgggaagata catcgaatac acgaaaagag
    30841 tatgatgcag atttggaaat ttacggctat aatcgttcag gcttattgaa tgatgtactt
    30901 caaacagtca atgcgctaac gaaaaatctc aacagcgttg aagcacggac gaataaagat
    30961 aaaatggcga cgatccattt gacggttggt atccagaatt tatcccacct aaagagtatc
    31021 gtggataaaa tcaaagcagt acctgatgtc tacagtgtac gccggacgaa tggataggag
    31081 gacagatatg agagcagttg ttcaacgggt aagtaaagct gctgtgtcag tcgatcagca
    31141 agaaattgga aaaattggct acggcctact tgttttatta ggcattcatg aaaccgatac
    31201 gcaaaaagat gtggactatc tggtaaaaaa aattgcacaa atgcgtattt ttgaagatga
    31261 acaaggaaaa atgaatatta gtgtagaaga tgtgggagga caaattttaa gtatctctca
    31321 attcacactg tttgcggata cgaaaaaagg aaatcgacca agctttgtgg aagccgcacg
    31381 accagaaaca gctattcctt tatacgaatc attcaatgaa ggaatcagaa gtcgcggcat
    31441 cacagtcgct accggacaat tcggagcaga tatgtcggtt tctctcgtca atgatggacc
    31501 tgtaacgatc attattgatt ctaaaaacaa ataaagtaat ctggttttca ctagtaaaaa
    31561 ctatgaaaca cgtcgcttaa gttagactga taaactctaa cttaagtggc ttttttgtct
    31621 gcaaaaagcg cttcttttgt cagcagtcgg aaaaaaagtt aagcttaaat tatacaagtt
    31681 attttttata ggaggttgct gaagatgaaa gaagtaccag tagtagatat caaaatcaca
    31741 gatttaaaaa aattgtatca aaaaggatac aacatgttgg aggagttacg ccatgaagcg
    31801 gacgctcccg tcgtcaaagc aaagattttc aataaagaag ctatcacgat ctacggatca
    31861 tcagcagcaa aagtatttta tgatccaagg aatttcaaac gaaaaggtgc tatgccaaaa
    31921 ttagtattga agacactttt tggtcaaggt ggagtacaga ctttggatgg agctgctcat
    31981 caccatcgga aaaatatttt tatggatcta atgacaccgg aaagaatgga agattatcat
    32041 cgtatcttag ataagaatct gacacaagca cttgaagcac agcatggtca atttgaacta
    32101 tttgatttaa gtaagatggt tttctttaca tctatttgcg agtgggcagg tatcaattta
    32161 tcagcgattt ctaaagatga ggtcgaaaaa ttagcagaat atcaaatctc tatgatcagc
    32221 ggaacgttta cttctccgat tgatcacata aaaggtgtcg aaaatcgcaa aaaatcagaa
    32281 aaatgggcgc aaggcttgat tgaagaagct cgacaaaatc ctgtggctgg aaaagaaaat
    32341 gtggcattat atgcttttgc caatgccaca gatttagatg gtcagctttt acctctggaa
    32401 gtggcagctg ttgaattatt gaacatcatc cgtccaacgg ttgctctaac tgtgtgggcg
    32461 gcattgatgg gacatgcact tttcagtaga ccagatttgt atcagcaatt aaaaaatgac
    32521 ttttcgacgt tacaagatcc gtttattcaa gaaatgagac gctattatcc tttcttccca
    32581 atgctacctg cgatttcgct gaaagaagta gaagtagatg gttatcgtat accagaaggc
    32641 agttgggtta ttttagattt atatggaaca gaccatgatg aacgaacagt tgaagcgcca
    32701 gattccttta tgatcaaacg gtatgtaggg aaagcaaaag atatttccta taaagaagaa
    32761 tatgagatga ttgcacaagg cgggggaaat tttcgacaaa tgcatcgctg tgcaggagaa
    32821 tggatcactc ttcatagtct acgtgtgttt tccgatcagc tagtaaataa gtttgagttc
    32881 tctgtacctg aacaagattg gacgattcca ttcaatcagt ttccgactta tccgaatagc
    32941 cgagcgctac tttacaagaa ttagattagc ataaacttat cgaaaaaaag gaagatcaaa
    33001 cagtgctgat cttccttttt tcatattact ataaattgat aaggtcaatt gatcaaaatc
    33061 cacgaaatgc ttcatcaatg gtttgataat cttcattgga taaatgcaaa tctaaagctt
    33121 ggacattgtc agatacttgc tctggacgct tagctccagg tataactaca gacactcgtg
    33181 gattcttcat gtaccaagct aaaacaagtt gcgcaggagt ggcttggtat cttttagcaa
    33241 tggggcgaag tacatcgaca gcggttaaaa tttctctgaa acgttctcct tggaaatctg
    33301 gatttctttt tcgaggatct ccttcaccaa attgtttttc ctcaccaagt tcatattttc
    33361 ctgtcagcaa accggaagca agaggaaaat agggaacaaa actgattttg tttttttcaa
    33421 gataagggaa taattctttt tcagcctgcc gatggatcaa actgtattta tcttctacta
    33481 catcgacata tccatctgca ttcgcttctt tcaattgttc taacgtgaag tttgacacac
    33541 cgactgctcg gatttttcct gcttctttta attcgtgcaa tgtagcaact gattcatttt
    33601 ttggtgtgct ttcatccgga aagtggatat aaaaaatgtc gatgtaatca gtttgcagac
    33661 gttttagtgc atcttccacc gattgtttga gaaactcagg agaattatca aatgttcgcc
    33721 ctttatttgg tacatgagca gcttttgtag cgatgacgac acgtgagcga tcatattctt
    33781 tttccttcag tacctcgcca atcagttctt cggaacggcc gtttccgtaa gcataagcgg
    33841 tatcgatcaa attgatcccg ctattcaaag ctgtacgaac tacttgtttt cctgtctcat
    33901 cttccaaacc gtcaaaaaga ttatgtcctc caacggcatt tgctcctaat ccaagctgtt
    33961 ctgcgtagac ttgtgaatgt ccgattctta tttctgccat agctgattcc tcctttttgt
    34021 ctagtctaaa acaaaatacc aaaaagctga actaaaacgt ttttgtgagg ggaaatagtc
    34081 agatatctct tgactttgag actggttttt agtaggttat aagtaatatc gaatgtcaat
    34141 gaaagagcga gtaagttttt gaaactttac aagagaggat catcgaggct gaaaatgatc
    34201 taaagtttca ttagcctaaa gacactctgg agatggacga gtgaaaagcc gtcccgcgta
    34261 cgagcgttat tcgtaagagg aaagagaaat ctttcaaaat taggtggtac cgtgtatgaa
    34321 tttcattcac ccttgttcat gatgaacaag ggtgattttt ttatttacat agctaagaaa
    34381 gggagagaaa actatgagtt tccaaagacc aaaaggaaca aatgatattt tgccaggcga
    34441 atcagaaaaa tggcagtttg tcgaagaaac agcacgttta ttattcagag attatcagta
    34501 taatgaaatg cgtacaccga tttttgaaca ctatgaagtg atatcccgaa gtgtagggga
    34561 tacaacggat atcgtttcaa aagagatgta tgatttttat gacaaagggg aacgccatgt
    34621 gacgcttcga ccagaaggta cagcaccaat cgttcgttct tttgttgagc ataaattgtt
    34681 cggcccagag tatgcgaaac cgttcaaaac tttttatatg ggaccaatgt ttcgctacga
    34741 acgccctcaa aaaggacggt tacgtcaatt ccatcaaatc ggagtagaag catttggatc
    34801 agaaaaccct gcaactgatg tggagagcat ggtgatggca cttgatttct tcaaacagtt
    34861 ggggatcacg caaatccggc tagtcatcaa ttcattaggt gataaagaaa cgcgtcaagc
    34921 ctatcgtcaa gcattgatcg actatctttt accttttgaa tcagagctga gtgaagactc
    34981 taaacgccgc cttcatgaaa atccattacg cgtattggac agtaaagaca aacgagatca
    35041 aaaatttgtg gcagaagctc catctatctt agattatcta agcgagcctg ctcaaaaaca
    35101 ttttgatacc gttgtttcca tgctggatgc attggctgtt ccttatgaaa tcgacagtaa
    35161 tatggttcgc ggactagatt attacacaca tacgattttt gaaatcatga gtgacgcacc
    35221 aaaaatgggg gcacaagcaa cgatttgcgc aggcggacgt tatgacaatc tagtggaaga
    35281 actaggtggt ccttcaacac ctggcttcgg atttgcaatg ggtatcgagc gattactctt
    35341 gactatggag gcagaggaag tagttatccc tgcatttaat gagttggatg cttacgtggt
    35401 cgcactcgga gacgaaacaa atatcgaagc attgaaagtg gtccaagcga ttcgaaactt
    35461 tggtttttca gctgaccgcg acttcatgaa ccgtaaagca aaagcgcaat ttaagacagc
    35521 agataaagcg aatgccaaat tagtattggt gatcggtgaa gatgagcttg ctagtcaaac
    35581 gattaatgtc aaagcaatgg caagccgaaa agaaaaaagt tttccattag aagagatata
    35641 tgaacatttt gatgaagtct atgatgaaat gactttattc gagtaggagg aaaaaaataa
    35701 atggcacaaa gaacgatcta ttgcggatta gtttccgaac aacaattaga acaaacagtt
    35761 acattaaaag gatgggtaca aaaaagacga gaccttgggg gagtaatctt tatcgaccta
    35821 cgtgatcgtg aaggaatcgt tcaaatcgtc tttaatcctg aaatcaacaa agaagcatgg
    35881 gaaatcgcgg ataaatgtcg cagtgaatac gtgatcgaag tgactgggga agttagaaga
    35941 cgcggagaaa atgcagtaaa tcctaaaatg gccactggtg aattcgaagt gattgcaagt
    36001 gaaatcgtga ttttgaatca agcaaaaacc ccgccatttc aaattgaaga tgatcaagca
    36061 atcagtgacg aaatacgttt gaaatatcgt tatttggatc tgcgtcgtcc aaaaatgact
    36121 aaaaacatca aattaagaaa tgcgacaaca aaagcgattc gtcattattt agatgataat
    36181 gactttctcg atatcgaaac accttaccta gggaaatcta caccagaagg cgcaagagac
    36241 tacctagttc cttcacgtgt ccatgctgga catttctatg cgttgccgca atctcctcaa
    36301 ttgtttaaac aattgctgat gaatgctgga ttcgaccgtt attatcaaat cgttcgttgt
    36361 ttccgcgatg aagatttacg tggagaccgt cagcctgaat ttacgcaagt agatattgaa
    36421 acaacgttct taacagcaga agaaatccaa acttacacag agggattgat tgcgaaggta
    36481 atgaaagaag ttcgcggtat cgaagtcaca ttgccatttc ctcgtatgac ctatgatgaa
    36541 gcaatggctc gctacggcag cgacaaaccg gatacacgtt ttgatatgga attgatcgat
    36601 ctaagcgata cagtcaaaga agtagaattc aaagtcttcc aaatggctct tgaaaacggc
    36661 ggtgtcgtga aagcattgaa tgctaaaggc gctgcagatc gctactcacg aaaagacatg
    36721 gatcagttag gtcaatatgt aggacaattc ggagctaagg ggcttgcatg gctgaaagta
    36781 gaagaagacg gattgaaagg tccaattgct aaattcatgg gagaagcaac agaagcaatc
    36841 attaaagcaa cagatgcaaa accaggtgac ttgctgatgt ttggcgcaga taaaagtgaa
    36901 atcgtcgctg ctgcattagg tgctatccgg acacgtttag gaaaagaatt aggactaatt
    36961 gatgaatcga aattcaattt cttatgggta actgattggc cacaatttga attttcagaa
    37021 gaagaaggtc gatatgtctc tgctcaccat ccattcacga tgccaaaaga agaagatatc
    37081 ccgttattgg ctgaagaccc tgcaaaagtc tatgcagaag cttatgatat cgtcttgaac
    37141 ggttatgaac taggcggagg ttctatccgt attcatactc gtgagcttca agaaaaagta
    37201 ctagaaactc taggctttac aaaagaacaa atggaagaac aatttggttt cttgttaaca
    37261 gctttagatt acggattccc tccacatggc ggtattgcat taggattgga ccgttttgca
    37321 atgttattag ccggagaaga taatattcgt gaagtcattg cctttcctaa aaacggaaaa
    37381 gcagcagatg tgatgagtga tgcaccaagt atggtttcgc ctttacaatt gttcgaattg
    37441 aatattgatg taacgaatat agaagaatag ccgataaaaa ggtaaaaagg atttgtcgaa
    37501 tacgcttctt ttgacaacct tgatttaatt gaaaaacact ttataatgaa gccataacat
    37561 ataaagcggg gcttttccat gaaaaaaaca ttcgaaaatt gggcttatca tgattacacg
    37621 accaagcttt cggtatctat cgtttatgcg ttgatcgcat cagtcgcatt gaatttcttt
    37681 tatcagccag gacatattta ttcaagtggt attactggtc tagctcagat tttgacgact
    37741 ttgtcaaaat cactgatagg attcgaagta ccggtatcaa caactttgta tttactgaat
    37801 atacctttgt ttgtattggc gtggttaaaa atcgggaaga agtttacaat tttcactttt
    37861 atcacagtca ctttgacctc cctttgtatc catattttac cggaaacagt cctatctacc
    37921 gatccaatca tctgtgcgtt gtttgggggg gctgtgatgg gactaggtat tgggctagcg
    37981 ttgagaaacg gcctatcatc gggcggtcta gatatcgtga gtatcacgat tcgtaaaaaa
    38041 acaggaaagt cgattggttc tatttcgatc tacttcaatg cattgatcgt ttttgttgcc
    38101 ggaattctat ttggctggca atatatgttt tacagtacgt tgtctatttt cgtcagtgga
    38161 aaagtaactg atgtcgttta tactaaacaa aagaagatgc aggtaatgat cgtaacgaaa
    38221 catccagaaa aagtagtaaa tgaaatccaa aactgtatgc gtagagggat cacgatcatc
    38281 aatgaagcag aaggtgctta taagcatgat aagcagacag tattgatgac gatcgttaca
    38341 cgatacgaac tgcctctact tagagaagca atgaaagctt ctgatccaca agcttttgta
    38401 agtattgcag aaaacgtcca gatacttggt cgtttctatg aggatggcat ttagatcgag
    38461 tttgacaaaa attcatgaaa tactgctgta gacagacgtt cgtttgtctg cagttttttt
    38521 ctaccatagt agaatcagca aagaaaaact gcttttttat ttgaaatttt cttaaagttg
    38581 aaaaaaagca tgtttatttt tttaaattta tgggatgata gaaaaaaata gtagagaaag
    38641 gacacgattc tacttgctat tttcacttaa tacccgtata ttacgaatga aaaaagttta
    38701 tgaaaagttg gaatattgaa tggaaaaaca aaaaaggtta aaaaacagcc gctacatcac
    38761 tgggtttgat gggctccgtt cattagctgt ggtgggtgtt atcttctatc accttctgcc
    38821 aactagtatg aaaggcggct atttgggcgt tccgattttt ttcgtcgtat ctggttattt
    38881 gatcacggat ctgctgcggc aggaatggga acaaaatgga aaaatcaata tttggcaatt
    38941 ttatgtcaga agaatgaaga gactctatcc ggcacttgtt tttatgcttg tgacagcttc
    39001 ggcttatatc actttgtttc agcgagggct gttaaacaat cttcgaggag ttgtggtcag
    39061 cagcttactg tatgtcaaca actggtggca aatcaataac ggtttatctt atttcgatcg
    39121 atttgctaat gagtcaccgt ttacgcatat ctggtcttta gcagtagaag gtcaaaacta
    39181 tttggtttgg ccgatcttgt ttgtattgtt gatggtattt gttcgtaaaa gaaaatggat
    39241 cttttatact gtgttaggta catccttcct ctccgccatc ttgatgatga tcttgtatac
    39301 accaggaggc gatccaaccc gtgtttatta cggtaccgac actcgtctgt tttctatatg
    39361 gttgggaagt gcgcttgcgt ttgtttggcc aagtacgcgt ttaaagaaaa acatcccgaa
    39421 acaagcgaaa aatattctga atatcgctgg aggaatctcg cttttggcac tgattctttg
    39481 cttcttcttt ttagatgatc attacaattt catctattac ggaggaatgc tcctagtgag
    39541 tctgttatgc gtagtgctag ttgcagtgac agcacacccc ggagcaagtt tgaatcgatg
    39601 gctgacaaat ccagtattta cttggattgg caaacgaagc tatggcattt atctgtatca
    39661 gtttccagtt atgatttttt atgaagcaaa ggtgactgat attgccgatc atgttttgtt
    39721 gcatacttta gtggaaatca cattgattct aatcatcagt gaactttctt atcgatatgt
    39781 ggagcgtccg ctagcacgtt ttgattatgg tcgtacattc caagtgatga aaggatggtt
    39841 cagcaaaccg atcatcagta agagcaaacc atgggttgtt ccaggcacat tacttgtagc
    39901 aattgcactc gttggtttcg ttacggcacc gaaaaacgct gtaacagccg atcaaaaaca
    39961 actgcaggca aaaatcgctg aaagtaaaaa attagcagaa gaaaccagaa acaattcaga
    40021 aaacaccact agttcggttg accaagcgat ccttgataag tacgagttgt ccaaggcaca
    40081 agggaataag gcacaaaaat tagaactaac ggcatttggt gattcagtta tgttggatgc
    40141 tgcaacggat ctacaagaac tttatccaaa agtagtggta gatggagatg tcggacgaca
    40201 attatatgcc agtgtaccgt acattgaaaa attaaaggaa caagatttgt tgaaagacac
    40261 tgttctgatc ggactaggaa cgaatggctc attctcggaa gctcagtttg atagtgtgat
    40321 ggatgcaatc ggtgatcgaa aagtatactg ggtcaatgtc cgagtaccga cgaagcgctg
    40381 gcaaaatgac gtgaatgcga tgcttgaaca gatgacgaaa aaatacgaca atatgacgct
    40441 gattgattgg tacagctaca gtaatgacca tagtgactgg ttttatgatg atcaagtcca
    40501 tccaaatcct gaagggatga cacattacat tcacttagtc agcgaagcct tgctaggagg
    40561 aagttcaagt acgaacagca gtgagacaaa cgtgacagaa tgatagctac aaaaaacttc
    40621 aggcaaaaac atttgttttt gcctgaagtt tttttatatt taccgtgttt ttaacattca
    40681 tatagattca ggaagcaaaa cggttgagtg tgtctgtaaa taacgttctt tttgttttcg
    40741 ggtgagtttt ttgaatgcag cttctgcttt tgttgcttcg cttcttgaag aaaatacttc
    40801 tgcatggatc atcttaacag gtcttctttt ttgaagacga gtatatttag caccagtacc
    40861 attgttatgt tcctctaatc gtctagaaag atcggttgta tatccaccat aaaatgtctg
    40921 atctttacag aataatacgt aaaaataatg ttcatttgcc atagagcatc tcacgaatct
    40981 ctgcagtgta ttctccatcc atattgtaag tgatcaatgg tggagcgact ttgaatccgt
    41041 ctaatttgcc ttctttgatt ccttcaacta acaaaatatt tgcctctttt ccaggttttg
    41101 ggtaaacaaa ttggatcctt ttaggtgcaa ttcgatagtc ttccatgacc tgaatgattt
    41161 ctaagaaccg atcaggacga tggaccatag taaagcgtcc atttgttttt agtagcttac
    41221 ttgaaatatc gatcacttct tctaacgtcg tatgaatctc atgacgggcg attgccaggt
    41281 gtttattagg gttcgtttta tttgttggca gccctttgaa ataaggtgga ttacagacga
    41341 ctaagtcaca agaattatgt cgaacgacag ataagctgtc tttcagatcg atggtgtgga
    41401 cagtcatttg ttcatttaaa tggttaagcg cgatactacg tcttgccatg tctgctagac
    41461 gaggttgaag ttcgatagcg tcgatagccg cctgggttcg tttacttaaa aaaagtccaa
    41521 ctgcgccatt tcctgcacaa aggtcaacaa tcttcccttt tttaggtaca cgggaaaagt
    41581 gagcaagcag cacagcatct aaagaaaaag aaaacacttt ggaactttgg ataatcttga
    41641 tatcttctgc gtataattgg tcgattcgtt cgtcttcgtg aagcatggat tccctccaaa
    41701 atgaaaaaaa tagtcgtctg tattatacta tttttattaa aaagaaccaa ggtggcttgt
    41761 caaacctcta ttttttatgc atactatgac cataagaagg gaaaggaaga gactatgttt
    41821 tatcgattta tgcgcggggt agttcgagta ctattagcct tagttaatgg aaatgcccgc
    41881 tatgagaata aagaagtttt accgcaagat gagaattaca tactagttgc tccccatcgt
    41941 acttggtggg acccattata tctggcggta gctgcagcac ccaaggaatt cagctttatg
    42001 gcaaaagaag aactgttcaa aaatccagtt ctgcgattta tattaactcg atccaatgct
    42061 tttccagtta aaagagaaaa tccaggacca agcgtcatta aaacacctgt aaagattttg
    42121 aaatcgacaa atttgagttt gatcatgttt cccagtggga caagacatgc tacagaactt
    42181 aaaggcggaa tggcattgat ttccagaatg tctaaagcga aaatcgtgcc agctgtatat
    42241 caaggtccgt tgacacttgg ggatctgttc aagcgtcaga gagtgacagt gcgtttcggc
    42301 gaaccaatcg acttatcaga tatcaagaaa acggataaag aaggtatggc ggagatcgaa
    42361 cgacgaacac aagcagcttt tgacaaattg gacaaagaag tgaaccctga tttcaaatat
    42421 gaagtcaaaa aaaaataaaa tgataagttt atgcgtgggc ggtcttttga atctactgtc
    42481 ctgttcagtt cagacttttt caatgaaaac gagggagaga cgtcaagtct gccctctttt
    42541 tgcgttccaa tatgtaaaat agaagacagg tgtcatgtaa tggatcaaag tgttataata
    42601 attagaagga cattttttga ggtgattgaa tgcgtttttt acatacagcc gattggcata
    42661 tcggaaaaaa actacaaggt tatgacttga ttgaagacca gcgtcatgta ctatcttcta
    42721 tactagatat cgcgaaagaa gaaaaagtag aggcaatcgt gattgccgga gacttatatg
    42781 ataggagtgt cccagctgtt gatgccgtag aattatacaa tgaattgatg gtcgattgga
    42841 atttaaagga aaagatcccg atttttgcta tatcaggaaa tcacgatagc agtacgagac
    42901 tttcagcggg tacgccatgg ttcagttatt cgaactattt tttgcgaaca cagctagcag
    42961 aagcatttga accagtcgag tttaaaaacg tacaattttt ctttcttcct tactttgaac
    43021 caattgcagc gagattatat tttgaagatg acaatatccg aacgatcaag caagcggtag
    43081 ccaaggtgat agataaaatg caggagctat ttgattcaga aaaaaaacaa gtattgatta
    43141 gccatttttt tgtaatggga agtgtaaaat ctgattcgga aacgaaaatc gaagtaggcg
    43201 ggttggattc gatccctggt gaactactta caccgtttga ttatgtagca ctaggacatt
    43261 tgcataatca agctgctttg agacaggata atgctcgcta tagcggttcc ccattgaaat
    43321 tctctttatc tgagatcaac caaaaaaaag gcgtatggat cgttgacctg acaacaggcc
    43381 tggagttgaa ttttagggag atcgaacccc tgcatgatat tgaagaaata acagcgagtt
    43441 tcaaagaatt gctggatcct gccttttatc agtccgtcaa tcgggagaat tacatctata
    43501 tctatctcac tgatagaacg atcatcccga atatgatgaa ccagcttcgg caaatatatc
    43561 ctcgtatttt ggggattgaa cgggcaaacg gtcgagcaga acaaacaaag cgcaaacgaa
    43621 aagtactaga aatgaaagat cctcaaaaat tagcagaagc attttttagt gaaatgacgg
    43681 aagagcagct aactgcaaac caagaaaaat ggctcggaga aacgttgcaa gaaatcatgg
    43741 aaatggaatg atcaagaatg aaaccgaaaa aattacaact taaaaatttt ggtcctttta
    43801 tcaatgagac cgtagatttt tcacgtttga cagaagcacc gctttttttg atcagcggga
    43861 agacaggagc tggcaaaacg acgatttttg atgggatcac cttcgcactt tttggtgaaa
    43921 cttccggaag acttcgctct ggaaaagaga tgcgttcttt gtttgctaca ccagacgaag
    43981 aaacaagcgt gactttttct tttgaacatc agcagatgag ctatgaaatc gaacgaaaac
    44041 cagaacaagt tttagcaaaa cgaaaaggaa acggaacaaa aaaacaggca gccaaagtaa
    44101 cgttgaccat ttttgatggg aaaggaaaag aaataaaaca aatcacaaaa cgtacagaag
    44161 cagatcagtt gatcagagaa ctgatgaatc tcgatgcgaa acagttttct caaatcgttt
    44221 tactacccca aggagaattc cgtaattttt tggtttcatc aagcagtgat aaagagactg
    44281 ttttacgtca tttattcggt actcaatttt tccaacagtt caatgagcga ttaaaagaaa
    44341 aagcaaaaca acagcaacaa aaattggatc atttagagca agagctgcat cttctgcaaa
    44401 aaaggtttgt tttagtcaaa gaagaggaac cagcagcagg gtttgaagcc gttttagccc
    44461 aatggacaaa ccatcaggca atactcgaaa aacaaatcac ggaagaaaaa gaagctctaa
    44521 cggaacttca ggaaaaacaa aagcaactag aaaattccta ctatcgtttt gaaagcttga
    44581 aaaaaagtta tgaagaaaaa acgatattaa taaacaagca aaaggaatta gctgctcaaa
    44641 aagacgaaat agaggaaaag aaacgatgga ttgggtatta tgaatttacg caacgattag
    44701 tcgaaccaat ccagcgccta caagaaataa aagttgaaaa aatagaactg tcacaaaaaa
    44761 gtagtgagca aacaaagaaa ctagcgatga ctacgcagaa ttatgaagag tggcaaaaaa
    44821 atgaagcaaa ccgcgtacgc cgacaaacaa aaatcaaaga agctgctcaa aaactgcaaa
    44881 acaaacagat gatggtgcca attgtcgaat ccttacgtag taaaaaacaa gacgcagaac
    44941 aattaacaat ttcattggat aaagaagaat tgaatgccga gaagctgtat caaaatctcg
    45001 ctatctatca ggaaagaact cgaattcttc aagaaaattt actggatcag gaaaaactgc
    45061 aagaagatcg tcttgctttt ggacagttaa aatatctaga tgaaaagcag caagaaatag
    45121 aaaaacaaaa agcaaaagac actgggtcgc tcgcacagat aagagaagaa ctcaaaaaag
    45181 caactgaaga aataacaaaa aatagtcagc tattgaaaga acagacagaa caagcagaac
    45241 agctgaaaag ccaatgggca aagcagcaaa ttgctcgtct tcagcttttt ttgcgtccag
    45301 gggagccatg tcttgtttgt ggatcaacgg aacaccccat acaacaatta aaacacgaac
    45361 agccaaataa ggaagatatc ttaaaagtag aacaacaact ggcagaagct gagtctgctg
    45421 tagaaagaac tcagcaaatc attgccaaaa gtgaagcaca tgaaaataat cttcaacaac
    45481 aattatcaga tttagaacaa aaaatcatgg caacgaatat acaattggct gaacaagaag
    45541 aacacttgca acaggctttg aaaaaggcat ttcctgagat aacagaacaa aaaacaaaaa
    45601 caactcttgt agtaatcgaa caatctttag atagacgaaa aagcaagatg gccaatgcaa
    45661 gaatagagct ggaagaaata agacaacaag cagaaaagct cgaacaacaa ttagctgtct
    45721 acaaacagca gcagacagaa aaaaataatc agctccagca actgcaagga gaaatcaaaa
    45781 gtttagaaca acaattgcaa gatacggata gtaactgttt agaagaggag atacgacgac
    45841 ttgaaaaaca gttagaagaa gactcgaatc aactagctgt tgagcagaaa gcaggagtgc
    45901 aattgttgca agatcttcat acgcttcgga cacagcttga tcttcaacat gaacaaatag
    45961 aaaaaataga tgaaaaaata gaaaaggaac aagaaagaat agctaaaaag ttagaaagcc
    46021 agtcgtattt ttcaacaatt gaagaaatct gtgcatttgc acaacagcaa gcacaatata
    46081 aagaaaacca acgtacagtt acttcttatc atgaagagca attagtgaca gctgaccggc
    46141 tgcgtcaatt agaaaatatc cagctaactg agacattccc agatacagaa gagatcagcc
    46201 aacagttaga agaaataaga cgtatgatcg aaataaagca agaaaagata tacggtttac
    46261 aagaacaaaa aattagtaat caaaaaatct acgatgaatg tctttcgatt tatcacacaa
    46321 gccagacgaa attagatgag cttacgcaat tacagcagct ttcgcaaaca ttcaacggag
    46381 aaaatcctaa gaagactagt ttggaacggt atgtgcttca ggtttatctt caagaagtgt
    46441 tacaagtagc aaatgatcat ctccaacgtt taacgaaaaa tcgttatcaa tttgagctag
    46501 cggataccat tggcagttat cgagggaaaa ccggattaga aatcaatatc tatgatgatc
    46561 aggcaggtat gtctcgaagt gcgcataccc tgtctggcgg tgagagtttt attgcagcac
    46621 tttctttagc attagctctt gccgatgtga tccagacaca agctggtggt gtagcaatcg
    46681 atgcattgtt tattgatgaa ggatttgggt cattagatga agaagctttg gaaatggcaa
    46741 tggaagcttt agaaacgatc gaaagtgaag gaagaatgat cggcatcatt agtcatgtaa
    46801 gagaattgaa agaacgagta ttacaacaaa taagaattga tacagaaggt agcggacaaa
    46861 gcaaaatacg ctatcaactt ggataaaaag ggagattggt aactatgaaa tggagtattc
    46921 cagaaaaagt cattgcacgt ggacgtcaat acttgcaaga aggccgagtg ttatcggttg
    46981 tccctgacca agaagaaaac gtgtggcatg cagaagtctt gggcagtgaa ttgtatatgg
    47041 ttgatttgga tggtacagca aaagagatag attactgcca atgtccctat tgggaggaac
    47101 ataaatattg taagcataca gttgctgtgg aactttattt acggtcgaaa aatctatctc
    47161 gtatcatgaa aaaagaccag ccaatgctag aaccggtaaa agcaacaagt gagggagaaa
    47221 tcattgcaaa aggtttttct cgtctaaaaa cacaaaacaa tcctcaagcg gtgcaacctt
    47281 tgattattga ataccaagta gaaacgattg agactaatca gtatcaccca gagctttcta
    47341 ttttggcact ttacttgcgt atcggttcat tggcatcacc gaaaaaaaca tatatcgtaa
    47401 aaaacatcta tgatttttta caagcttaca cagaaaaaga aacttacact gttaataaac
    47461 agtaccagtt tcgtctagat aaacgggcgt ttcaaaaaga agatcaaaaa atactcacgc
    47521 atcttgcagg aagtgctcag acgcatcaat tattaggtac gaacggctta caagtcaaag
    47581 gaaaactaga taaaagatat ctgcttctcc cagtagaaca agcccgcttc ctgttagagc
    47641 agatgaatca gactacacgt ttgcatctgc agataaatga acaaaacgat caaggaatac
    47701 aattttccga tcaaaacaaa cctttatcat tcaaagtgga aaaatttgga gaagattatt
    47761 tgctgcaagc attgaatgat tttgattttt tctttatgca ttatcagtgg ggagttatcc
    47821 aagggacatt ttattctctg acgaaatatc aacaaacggt ttatcaaact tggaaacaat
    47881 tgattcgccg attggagaaa ccagaagtag tgttcaagaa aaaagaatta ccgtctttgt
    47941 ttaaagagat tatccctctg ctgtcagaga tcggcgacgt agctattgcc cctgcagtag
    48001 aagaggaagt agcagatatc cccgtcgaat ttattttctt tttccgaaaa gcaaaaggaa
    48061 aaatccaagc tcgagtcgat ttcgtctatg gcgaagtcat ctattcgact gacccgaagc
    48121 atgaggtctc gacagaacag gcttttcagg tgttacgtga cacagtagaa gagaaacgag
    48181 tacttgatct attcagaatg tatcgctacc agaaaaatga aactggttat gaacgtccat
    48241 tgccaagcgg ggaagaacta tatgcctttt tccgcacaga actatctgtc ttccgtcagt
    48301 ttggtgaagt cagacttgga agaaaattgc gagagttgta tttagatgcg cataaacatc
    48361 aaccgaaaat cgaagtaacc gagaccggtt catggctcga tattcgattc gatgtgacag
    48421 ggatagagga gcaagaaatc gatcatgtcc tgcaaagctt gctgagaaat gatgcttttt
    48481 atacattaga aaatggtcag gttctttctt ttgattcaga agaatttcaa caaacaagcc
    48541 aagtgttgca acaattacgg gaatcgatac gtacagaaga aggaacgatc catgtaccta
    48601 aaaatcaagg attgatcatt caaaatcaat tggaaaaaag caatgctact tttagtgaat
    48661 cgttccaaac gatggtacaa gatctcattc atccagaaag ataccaggca cagcttccca
    48721 aaggattgaa tgcaacgatg agagattatc aaaagcaagg ttttcgatgg ttgaagatgt
    48781 taggtcatta tcagtttggc ggtattttag ccgatgaaat gggacttggg aaaacactac
    48841 agacaattgc ctttttactt tcggaaaaag aagaacggaa aagcttctct gctttgatcg
    48901 tagcgcctgc gagcttaatt tacaactggc aggcagaggt gagaaaattc gccccttctt
    48961 taagtatcca agtaatcaat gggaataaaa aagaacgtga agaattactg gctaaagaca
    49021 cagatatccg agtgacttct tatgccagct taagacagga tctagctaat tatcagtcgc
    49081 aaaaaattga ttatttgatt cttgatgagg cacaaatggt caaaaatagc agtacgaaaa
    49141 ctgcacaagc attgagagaa ttagctgtac ctcagcggtt tgcactgagt gggacaccaa
    49201 tcgagaataa tttagaagaa ttgtggtcat tgtttgcaac gattatgcca ggatttttcc
    49261 cgactaaaac aaaattcagg gaacttgccg cagaagaaat tgcgcaaatg attcgaccgt
    49321 ttattttacg gcgagataaa caaactgtgt tgaaagactt gccggaaaaa acagagatga
    49381 atctatattc tgcacttaca gaagaacaaa aaactgttta tttagcttac ttgcgtcaaa
    49441 tgcgtgaaga aatcacatca atggattctg aagcattcaa gaaaaaccgg atcgggatac
    49501 ttgctggtct gacaagactg cgacaaattt gctgcgatcc tcgtctgttt attgaagatt
    49561 accaaggcgg ttccggcaag ctcgaacaag taaaagatct actggtagct gccaaagaga
    49621 acaaacgaag agttttgctg ttttctcaat ttacagggat gctgactatc ttgcaagaag
    49681 agttagccga gctagggatc tcgacatttt atttaagagg cagtacgaaa ccacaagatc
    49741 ggttaagtat ggtagacgca tttaatgctg gcgaaaaaga tgtttttctg atttccttaa
    49801 aggctggggg aactggattg aatctcacgg gagcagatac ggtcatcttg tatgaccttt
    49861 ggtggaatcc tgccattgaa gaacaagctg ctggacgtgc acatcggatc ggacaaaaaa
    49921 atgtggtaga agtgtggcgt atgatctctg aaggaacgat tgaggaacgc atggattcac
    49981 tccagcaaga aaaacgcgaa ctgttccaaa aagtgatcca aggtaatgaa gaacagttga
    50041 cgaaactgac tgaagaagac atccgcatga ttttaagtgt aggagaaatc gaggagtaag
    50101 agactcgaaa aagcgttcag taatgggtaa gaaagccttt ctaaagaagc gattgtttat
    50161 ttgatttaaa aaatagcaag gaggctggga ttccatttta tcccagcttc cttgctatca
    50221 tttttttatt tctattttta aaggttatac aaagattgtc ttcattgtct ctaacagctg
    50281 atcaaaagaa gaaatctcga tatcgcaaat tggagtctgt tcaattttgc gttctcgatg
    50341 gttgaaccaa agcgcttgcc agttagcact ttttgcacct agaacatcat tgtcgtaatt
    50401 atcgccaacg tataaggtct cttctggaag catatgaaat tctttctcag ctagctgaaa
    50461 aatctctttt tctggttttt ggaaacctgt tgcttgagaa atgagcatat tgcgggaagg
    50521 aatccaattg ttcaattgaa gttgcttcag tttttttgtc tgatggtcag tcggcccatt
    50581 tgtgataatt cctaatggga cattcttttc cttcaagaaa tcgagggttt ttttgacctc
    50641 ctcatgcaag cagatattat caagttcttc ctcgtaaatt ttttgaaata agaggccatc
    50701 ttcttccgta atatgagggt agtctaaatc ttttagtgat tggctgatcc gatgtgctcg
    50761 catatattct agtgtccaat ctcctgccat tacttttggg aagttttcat cactatgatg
    50821 gcggaaccgg atatatagtg gatgcatatc tgcatctgaa acaagcggaa cgactctttt
    50881 gaccgcgttt cgaaatggct gctgctgatc atacatcgta tcatcaacat caaacacaac
    50941 tgatttaatc aaaattttac acgcctttcg gttttcattg attttttcac aaatccttga
    51001 ctattgtaac agaaaaaatt gtctaaaaaa gctgataaat aaaggttttt cttactatat
    51061 ttctatttcc ttgacagaat aaggttttta tatttcagtt tttttcacta aaaatcgtga
    51121 aacacgtcaa taagtttgat gaacaaatta atcattatgg tagaagtcga ttgatttatt
    51181 ttaatgcaat ctctgtggaa ttttcgaaag atttattttt ttaatacagt ctcaatataa
    51241 ctattcaaac ataaaataac gttatttgat ttatttgttt atagtaaatt ttatttagta
    51301 atcattgctt taaaatacta cgcttatata acagagaaaa taagcgttat aataaagaac
    51361 agtattattt aaaatgacag aaaacattac tattaaagaa ataaaaaaca taaaaaatct
    51421 taagaaatcg gtttcattta gcttttgaga taaaataata gtacagtttt atacgctgtt
    51481 tcatatgttt agaaaatttg aattagattt gaaaactcta atttttaaat gataaaaaaa
    51541 gcgagaatgc tggttttact gtatattaac cttagataac tttcattttt ttaaaaaaat
    51601 tatgaaaaaa aggtagctat ttaaaagttg attatgtata atagaaacag atgggagatt
    51661 attatgatct tctgttacaa aaaagtgatt cttatcacga aaaggagtgg tgcacgttgt
    51721 taacattata tacttcccca agttgtactt cctgcagaaa ggctcgtgcg tggttgcaag
    51781 aacatcagat tccatttgtt gaacgtaata ttttttcaga accattgaac agttctgaat
    51841 taaaagcgat tttacaaatg acagaagacg gaacagaaga aatcatctcg acacgttcca
    51901 aagtattcca aaaactgaac atggatttag atgatctgcc gttacaagaa ttattggaac
    51961 ttgtgcaaaa caatcctgga ttgcttcgcc gtccaatcat gattgatgat aaacgtctgc
    52021 aagttggttt taatgaagat gaaattcgtc ggttcctacc gcgcgatgta cgacaattag
    52081 aattacgtca agcacaattg atggctggat tatagaagga taatacgaaa cttggaaaag
    52141 actattacaa agatagtttt tccaagtttt tttgttttta caaaaagtat tcttgattag
    52201 atgtataaaa aggtagtaga agatgatgat tgcacgaaaa atagagaggg aaaattagct
    52261 gaaaagtcgg ctatatagta ttcgtctgcc aaaaatgtta tagttaaata agatagcttg
    52321 aaaggttgaa aaatccgctg gttttattaa attcgcttaa cagcgagatt ttttttcttt
    52381 acatttaagc tgatttcgct acaatgaatc tatattaaac attgtggcaa agtgaggtgt
    52441 agcaaaatgg aaatggaaca tattaatgaa aatacgatcc gtgtactaat tggtcatgaa
    52501 gatttagagg aacggggcgt ttcatttttg gatttacttg gcaatcacaa agaaatcgaa
    52561 aatttctttt atagtatttt ggaagaagtt gatatcgaag aggagttccg aggaagcgaa
    52621 gctgtcactt tccaagtttt gccaaaagga gacggattag aactgtttat cagtaaaaat
    52681 cttccggatg aagaaatttc tcaatcagaa gattctactg ttgattcaga agatgtgagt
    52741 gactttcttc gtcagcagat tattggcagc gatccggagg aagaattatc tggaagcgcc
    52801 ctagaagaac aggaaagaca agcaactttt gcttttgaag attttgaaca agtgatccaa
    52861 cttgcaacag atgtcgaact agagtctgct tggactgatt tgtatttatt cgaagagcgc
    52921 tattacctag tcgttcactt ctggatggaa aatctcaacc aagcggatgt agagaatcag
    52981 attgctcgaa ttttggagtt tgctgaaaag agcgatcgta caccagaaac attgaatgaa
    53041 tatggacaat gtctgatggc gcgtaatgct atcgagcgaa cgaaatttta ttttgtataa
    53101 atcagcatta tagtaagaga ctgtgacaaa aattgtgtcg cagtcttttt ttcgtataaa
    53161 tgtgttcaaa agcttgcatc tgcggtaaca agcccaacca aacgaaaaat attgggaact
    53221 atttttgttt agctgttctt attacttgat gcagaatagc tttttcacgc cctctttttt
    53281 cgtgtaaata aattcttaga cgtaaataag ttcagaggga gaaaaatgct gcttgcaatg
    53341 aatgaatata ataagtgctg ttttgctaaa catgcagaaa aaggaaagaa atattattgt
    53401 cgtggctgtc gaaaaagagt gattttgaaa aagggaaaga aaaaatgtgc tcattttgcc
    53461 catcaaaaat cagataactg ttcggtcttt agtgaaagag aatcaaaaga gcacttacag
    53521 ttaaaggaat gcttcatgga ttggctggga cagtcagtag aaccagtatt tttggaagcc
    53581 tatttgccga ggttgcggca aaggccggat attttgttgg cgaatctagc aatagaaatc
    53641 caatgttcta gactgtctca ccagagattt attgaaagaa cccaaaatta tttgaataac
    53701 agttaccaag tatggtggat acttggtaat tcttttcttg gacaatcgca attctcattg
    53761 atagaaaaaa gttgctgcta ctataataga aaaagaggag tgcattgctg gaaagctgat
    53821 ctcaagaaac aaaagcttta tttgtatcat catattacag agactgtatc agggcatatt
    53881 tccttttgca gtagctgctg gactttttct agtagggacc ttaaagaaat attcactagt
    53941 aacgaaatta aaatgaacca aatgaaaaaa atagaaaaag tgagtgaaga tgggaagaaa
    54001 tggctgacac gccaacttat tcacaagcaa aagaatacag tatccataca agaacaatgc
    54061 tacttgcgtc ataaacatct tttgcatcta tcatcgtgga tctatcaaaa aagtcggttt
    54121 ttcttttatt tacaagaaca ggtttttctt tatcgaatgt tgtacgaaga agccttggaa
    54181 aaccagaaag ttcctgattt caactcatgg ctttgccaaa taaaagaaca taaaagggaa
    54241 tggctttttc ctatgattga tgaagagatg gtctatcagc agttttttaa cgaatgcata
    54301 cacttgtctt ctttgaaaaa atagtaagta taaaaatagg ctaggaatcg gttttctatg
    54361 taaaacaaga tttagttatg ctaaaattga tggaagcaga cacatgaatg agtagaaaag
    54421 ttagatgctg tgacatgtgg atgttagact atgatctatt ttgatagata gagctaaggg
    54481 aagaaaagga gtggatttca tggaagtaaa gcagttgcca aaacgagaag aattgcctga
    54541 aaatttaact tgggacttga ccaagatctt ttcaagcgac caagagtttg atgagaaata
    54601 tttggaatta tcagaagagt taaaacaatc tgaaaaacac aaaggaacac ttgatcaagg
    54661 cgcttctcaa tttttaaatg cgattgaatt cgtattgagg gtttatcgcc aaactgaagt
    54721 catttatgta tatgcgcacc ttaaaaacga tcaagacact ggaaatacag attaccaagc
    54781 gctttatgca agagcaagca gtctgttttc gaaagttagt gaagccgttt cctggtttga
    54841 accagaaata ttgcaattgt cagatgacca gatttggcaa tatttcaaag aagaaccaaa
    54901 attggaagtc tatcgccatt atatccagca aatagtagat aatcgagccc atgtcttatc
    54961 tgctgagcag gaatctcttc ttgctggagc aggtgaaatc tttgatgctt caagtgatac
    55021 atttgctgtt ttgaataatg cagatctagt ttttccaacg attgaaggag aaaatggtga
    55081 aatagtccaa ttatctcatg gcgtgtatgg tcagttgcta gaaagcacgg atcgaagggt
    55141 gcgcgaagca gcatttaagg ggttgtacag tgtttacgaa caatttagaa atacatttgc
    55201 ttctacttta ggcacacata taaaaggaca taattttaaa gcgaaagtcc gtaattacag
    55261 ctctgccaga gaagcgtctt tgagcaataa tcatattcct gaaagtgtat acgatacttt
    55321 ggtagacgtg gtaaacaagc atttgccttt gttacatcga tacatggaat tacggaaacg
    55381 tttattagaa gtggaaaaac tgcacatgta tgatctttat acaccggtct taggggaagc
    55441 tccaattacc tttacgtacg aagaagcaaa agaaaaagct ttagaagcac tgaaaccaat
    55501 gggtgaagaa tacatggcca tcgtagaaaa agcattctct gaacgttgga tcgatgttgt
    55561 cgaaaataaa gggaaacgaa gcggtgctta ttcttcggga agctatgaca caaatccata
    55621 tattttattg aattggcatg atacgctgga tcagctattt acgcttgtcc acgaaatggg
    55681 acatagtgtt catagttatt tcactcgttc gaaccagcct tatgtgtacg gcgactactc
    55741 catcttttta gcagaaattg cttcgacaac gaatgaaaat atcctaacgg agtatttatt
    55801 ggaaacagaa aaagaccctc gtgtacgggc ttatgtactc aaccattact tggatgggtt
    55861 taaaggaaca gttttccgcc agacacaatt cgctgaattc gagcatttca tgcatacgga
    55921 agatgaaaaa ggtgtgccat tgactagtga atacctaagt gatagttatg gtaaattgaa
    55981 tgcaaaatat tatggtccag cagtcgaaga agacccagaa attaaattcg aatggtcacg
    56041 gataccgcat ttttattata attactatgt tttccaatac tcgactggct tttctgctgc
    56101 ttcagcactg gcgaagaaaa tactaaacca ggaaccagag gcactagaga actacttggc
    56161 ttacctaaaa gcaggtaaca gcgattatcc tgtggaagta atgaaaaaag caggagttga
    56221 tatgacacag gctgcatata ttgaagatgc aatgtcgatg tttgaacaac gtctaaatga
    56281 attagaagaa ttgatcgatc gtttataagg ctttctattt ttgattttct cgaatagaaa
    56341 cgaaaaaaat acgtcggctc tcttgtaagg gagtcgacgt atttt
//
LOCUS       DAXQKX010000013        55258 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.013, whole genome shotgun sequence.
ACCESSION   DAXQKX010000013 DAXQKX010000000
VERSION     DAXQKX010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 55258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55258
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.013"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..230)
                     /locus_tag="ACF3MF_000843"
     rRNA            complement(<1..230)
                     /locus_tag="ACF3MF_000843"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            complement(917..2422)
                     /locus_tag="ACF3MF_000844"
     CDS             complement(917..2422)
                     /locus_tag="ACF3MF_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFE3926862.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2419..3105)
                     /locus_tag="ACF3MF_000845"
     CDS             complement(2419..3105)
                     /locus_tag="ACF3MF_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFE3926863.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YEVLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(3298..4719)
                     /gene="gndA"
                     /locus_tag="ACF3MF_000846"
     CDS             complement(3298..4719)
                     /gene="gndA"
                     /locus_tag="ACF3MF_000846"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HFE3926864.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDEAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
     gene            complement(4889..5068)
                     /gene="rpmF"
                     /locus_tag="ACF3MF_000847"
     CDS             complement(4889..5068)
                     /gene="rpmF"
                     /locus_tag="ACF3MF_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HFE3926865.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(5126..5695)
                     /locus_tag="ACF3MF_000848"
     CDS             complement(5126..5695)
                     /locus_tag="ACF3MF_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HFE3926866.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            5881..6783
                     /locus_tag="ACF3MF_000849"
     CDS             5881..6783
                     /locus_tag="ACF3MF_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HFE3926867.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(6818..8602)
                     /gene="pyk"
                     /locus_tag="ACF3MF_000850"
     CDS             complement(6818..8602)
                     /gene="pyk"
                     /locus_tag="ACF3MF_000850"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HFE3926868.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(8676..9638)
                     /gene="pfkA"
                     /locus_tag="ACF3MF_000851"
     CDS             complement(8676..9638)
                     /gene="pfkA"
                     /locus_tag="ACF3MF_000851"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HFE3926869.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(9806..13120)
                     /gene="dnaE"
                     /locus_tag="ACF3MF_000852"
     CDS             complement(9806..13120)
                     /gene="dnaE"
                     /locus_tag="ACF3MF_000852"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HFE3926870.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            13351..13536
                     /locus_tag="ACF3MF_000853"
     CDS             13351..13536
                     /locus_tag="ACF3MF_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HFE3926871.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(13598..14794)
                     /locus_tag="ACF3MF_000854"
     CDS             complement(13598..14794)
                     /locus_tag="ACF3MF_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HFE3926872.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(14964..16400)
                     /locus_tag="ACF3MF_000855"
     CDS             complement(14964..16400)
                     /locus_tag="ACF3MF_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFE3926873.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            16693..17502
                     /locus_tag="ACF3MF_000856"
     CDS             16693..17502
                     /locus_tag="ACF3MF_000856"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFE3926874.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
     gene            complement(17688..19841)
                     /locus_tag="ACF3MF_000857"
     CDS             complement(17688..19841)
                     /locus_tag="ACF3MF_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan D,D-transpeptidase FtsI family
                     protein"
                     /protein_id="HFE3926875.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSKITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
     gene            complement(20236..21084)
                     /locus_tag="ACF3MF_000858"
     CDS             complement(20236..21084)
                     /locus_tag="ACF3MF_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFE3926876.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(21308..23248)
                     /gene="thrS"
                     /locus_tag="ACF3MF_000859"
     CDS             complement(21308..23248)
                     /gene="thrS"
                     /locus_tag="ACF3MF_000859"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HFE3926877.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTHVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(23585..23764)
                     /locus_tag="ACF3MF_000860"
     CDS             complement(23585..23764)
                     /locus_tag="ACF3MF_000860"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016862 - intramolecular oxidoreductase
                     activity, interconverting keto- and enol-groups [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxymuconate tautomerase"
                     /protein_id="HFE3926878.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(23811..25634)
                     /locus_tag="ACF3MF_000861"
     CDS             complement(23811..25634)
                     /locus_tag="ACF3MF_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFE3926879.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            25912..28191
                     /gene="helD"
                     /locus_tag="ACF3MF_000862"
     CDS             25912..28191
                     /gene="helD"
                     /locus_tag="ACF3MF_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase recycling motor HelD"
                     /protein_id="HFE3926880.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(28284..28931)
                     /locus_tag="ACF3MF_000863"
     CDS             complement(28284..28931)
                     /locus_tag="ACF3MF_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926881.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(29110..29829)
                     /locus_tag="ACF3MF_000864"
     CDS             complement(29110..29829)
                     /locus_tag="ACF3MF_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFE3926882.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(29960..31111)
                     /locus_tag="ACF3MF_000865"
     CDS             complement(29960..31111)
                     /locus_tag="ACF3MF_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HFE3926883.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(31328..32068)
                     /locus_tag="ACF3MF_000866"
     CDS             complement(31328..32068)
                     /locus_tag="ACF3MF_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFE3926884.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(32072..32395)
                     /gene="rsfS"
                     /locus_tag="ACF3MF_000867"
     CDS             complement(32072..32395)
                     /gene="rsfS"
                     /locus_tag="ACF3MF_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HFE3926885.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(32452..33045)
                     /gene="yqeK"
                     /locus_tag="ACF3MF_000868"
     CDS             complement(32452..33045)
                     /gene="yqeK"
                     /locus_tag="ACF3MF_000868"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HFE3926886.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(33029..33679)
                     /locus_tag="ACF3MF_000869"
     CDS             complement(33029..33679)
                     /locus_tag="ACF3MF_000869"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HFE3926887.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(33689..34000)
                     /gene="yhbY"
                     /locus_tag="ACF3MF_000870"
     CDS             complement(33689..34000)
                     /gene="yhbY"
                     /locus_tag="ACF3MF_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HFE3926888.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(34016..35125)
                     /gene="yqeH"
                     /locus_tag="ACF3MF_000871"
     CDS             complement(34016..35125)
                     /gene="yqeH"
                     /locus_tag="ACF3MF_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HFE3926889.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(35122..35649)
                     /locus_tag="ACF3MF_000872"
     CDS             complement(35122..35649)
                     /locus_tag="ACF3MF_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HFE3926890.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(35829..36614)
                     /locus_tag="ACF3MF_000873"
     CDS             complement(35829..36614)
                     /locus_tag="ACF3MF_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HFE3926891.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(36607..37476)
                     /gene="accD"
                     /locus_tag="ACF3MF_000874"
     CDS             complement(36607..37476)
                     /gene="accD"
                     /locus_tag="ACF3MF_000874"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HFE3926892.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(37477..38856)
                     /locus_tag="ACF3MF_000875"
     CDS             complement(37477..38856)
                     /locus_tag="ACF3MF_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HFE3926893.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(38864..39283)
                     /gene="fabZ"
                     /locus_tag="ACF3MF_000876"
     CDS             complement(38864..39283)
                     /gene="fabZ"
                     /locus_tag="ACF3MF_000876"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFE3926894.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(39308..39784)
                     /gene="accB"
                     /locus_tag="ACF3MF_000877"
     CDS             complement(39308..39784)
                     /gene="accB"
                     /locus_tag="ACF3MF_000877"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HFE3926895.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(39787..41022)
                     /gene="fabF"
                     /locus_tag="ACF3MF_000878"
     CDS             complement(39787..41022)
                     /gene="fabF"
                     /locus_tag="ACF3MF_000878"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HFE3926896.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(41041..41778)
                     /gene="fabG"
                     /locus_tag="ACF3MF_000879"
     CDS             complement(41041..41778)
                     /gene="fabG"
                     /locus_tag="ACF3MF_000879"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HFE3926897.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(41790..42707)
                     /gene="fabD"
                     /locus_tag="ACF3MF_000880"
     CDS             complement(41790..42707)
                     /gene="fabD"
                     /locus_tag="ACF3MF_000880"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HFE3926898.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(42814..43038)
                     /locus_tag="ACF3MF_000881"
     CDS             complement(42814..43038)
                     /locus_tag="ACF3MF_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFE3926899.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(43091..44053)
                     /locus_tag="ACF3MF_000882"
     CDS             complement(43091..44053)
                     /locus_tag="ACF3MF_000882"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HFE3926900.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(44063..44503)
                     /locus_tag="ACF3MF_000883"
     CDS             complement(44063..44503)
                     /locus_tag="ACF3MF_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFE3926901.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            44809..45774
                     /locus_tag="ACF3MF_000884"
     CDS             44809..45774
                     /locus_tag="ACF3MF_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFE3926902.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(45831..46061)
                     /locus_tag="ACF3MF_000885"
     CDS             complement(45831..46061)
                     /locus_tag="ACF3MF_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HFE3926903.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(46147..47034)
                     /locus_tag="ACF3MF_000886"
     CDS             complement(46147..47034)
                     /locus_tag="ACF3MF_000886"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFE3926904.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(47123..48346)
                     /locus_tag="ACF3MF_000887"
     CDS             complement(47123..48346)
                     /locus_tag="ACF3MF_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFE3926905.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(48363..49409)
                     /locus_tag="ACF3MF_000888"
     CDS             complement(48363..49409)
                     /locus_tag="ACF3MF_000888"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFE3926906.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYSIRVPIQAISNGIDLEKYRPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(49573..51300)
                     /gene="ptsP"
                     /locus_tag="ACF3MF_000889"
     CDS             complement(49573..51300)
                     /gene="ptsP"
                     /locus_tag="ACF3MF_000889"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HFE3926907.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDTMEEV
                     VELVHEYVK"
     gene            complement(51300..51566)
                     /locus_tag="ACF3MF_000890"
     CDS             complement(51300..51566)
                     /locus_tag="ACF3MF_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HFE3926908.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            52045..54279
                     /locus_tag="ACF3MF_000891"
     CDS             52045..54279
                     /locus_tag="ACF3MF_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFE3926909.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            54427..54747
                     /locus_tag="ACF3MF_000892"
     CDS             54427..54747
                     /locus_tag="ACF3MF_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HFE3926910.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(54952..55176)
                     /locus_tag="ACF3MF_000893"
     CDS             complement(54952..55176)
                     /locus_tag="ACF3MF_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HFE3926911.1"
                     /translation="METEWQIRERKKQKKEEMLRLCRLLDLKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
BASE COUNT        15710 a        11828 c         9600 g        18120 t
ORIGIN      
        1 gaaagcgcct ttcaaatcaa aaccatgcgg ttttgattgt tatacggtat tagcacctgt
       61 ttccaagtgt tatccccttc tgatgggcag gttacccacg tgttactcac ccgttcgcca
      121 ctcctctttt tccggtggag caagctccgg tggaaaaaga agcgttcgac ttgcatgtat
      181 taggcacgcc gccagtgttc gtcctgagcc aggatcaaac tctcataaaa agttcgaaca
      241 atcttgcgat tgttaagctc aatttgtttg ctagcatatt gcttgcttgt taaaaatgtt
      301 tgttgtcttg aattgaatca agacgcccta cacatttggt ttgtcttact ttgttcagtt
      361 ttcaaaggtc taatcttttt gtttcaacaa ctctttaatc ttatcagatt cagaagagaa
      421 tgtcaacaac ttctttgttt attttttcta aacgtctttg tcactcatta gcagcgactt
      481 gattatcata tcatctttat tgttatttgt caacaacttt ttcgaagttt ttttcgataa
      541 aatcaagctt tattagctac ctcatccaaa cgacttcgtt attataacat gacatcaaaa
      601 gtgcgtcaac cctatttttt ataattttta gtgacacctt aaaggaatca tttagaacaa
      661 ataataatat agcaatctct ttataaaatt gcaatagaaa attccctatt tttatttatt
      721 atttttaaac acgaatatta cagcatttca ttgttttttc gttcatctaa aagctactta
      781 cgtttaatta acggatgtta ttctatttaa ttgttcgcta gtttttttta taatgacatc
      841 cctgaatttc taacttgctt gtattttgta ccttattctt tgttggatat ataaaaaaac
      901 aagtaaagca catgctttac ttgtcttctg cctttgcgat aggaataaag attctaaaaa
      961 ttgtcccttg ccctactaca ctttctgcta agatacgtcc tttatagttt tcaaccagtt
     1021 gtttagcgat agacaacccc agaccatttc cacccttcgt tctagctctt gctttatcca
     1081 ctcgataaaa acgattgaag atcttattaa ggtcttcttt gggtattcct tcgccaaagt
     1141 cctgaatcgc gatctcaaat tcattcagag tggaagaaat agagatatgg acttcttttc
     1201 gtgtagttga atactttact gcgttatcca atatgataat gattaattgt tcaaagtgat
     1261 tacgataaat ttgcagggtc acttcttttg tcaaatcatc atctaaagtg atcacatagt
     1321 ctggatataa tatcttgaaa ttattataaa cttgataggt gacttctttt cctttagttg
     1381 tttcattcgc ataatgaaca tctacttgtt ctgctcttga taagtctagc atctcttgaa
     1441 ctaagctttt catacggcta atttcttgca tgctggcgct taatgattct tctaatatct
     1501 caggatcatc tttcccccaa cgatttagca gactaagatg cccttcaata attgcaacag
     1561 gtgtccttaa ctcatgagat acgtcttcca cgaattgctc ttgttgttca atatacaaac
     1621 gcatacggtc aagcatctca ttgaatattt cagctaaatc tgccaattca tcatttgtgt
     1681 cgatttcagg catgtggata tctgattgcg gatctttacg tatagtatcc attgtatctc
     1741 tgagtacctt gagtggtttt aagaaataag aagataaaaa gaaacctaaa atactactta
     1801 agatcaaaga aacaacttct aaaacaataa gagtcaataa tagcttattt cgaatatcat
     1861 agaaagaaga taattcatag aagctttgcg catagccgat cttttctctt gtacctttag
     1921 aatatatagg ctggatagat aaaaagccag tttttccttc tagtgtaacg atcgttggaa
     1981 ctttacgtgt agtctgaatc aggtttcgac tgttttcatg ggttttaaaa atcaagttct
     2041 cgtccaaatc ataaacataa agatccattg atggctgccc tagctcagct ataaaggaat
     2101 cgatcttcat taagtttcct tcgaccagtg aagtatgatc tacgacctca tctccgtcat
     2161 ttgtcgcttt cgtcagatta cgatacgtat ttactaatgt cagttcttca tccgagttag
     2221 ccaaacgaga agctacttct gaaatcgtac gctctacatt gtttctttct tttgccacaa
     2281 tcagattgat agatgattta taggtaatga cagcgaaaat tgtaaacaca acgaatatga
     2341 agaaagaact cgcaaaggcc cacttgattg tcaaggaggg ccctttcagt tctctttttt
     2401 ccgatttttt cggctttatc acgagcgcat cacataacct gttccgcgta cagtttggat
     2461 atagctttcc tccccgggaa cgtcaatttt gttgcgaaga taacgaatat atacgtccac
     2521 tacgtttgtt tcaacttctg tttcgtatcc ccacacttta tttagtaaaa cgtcacgtgc
     2581 taataccacg ttcacgtttt ccattaaagt aagcagcacc tcgtattctc tttttgttag
     2641 ttcaattact tcatttccgc gacgtacgac acggttttct ttttcgatag tcaaatcgcg
     2701 ataagtaata gtagtttgtt tagccacatt tttatcgcct tcaatatcga ttcgacgcaa
     2761 caatgcacga agacgtgcta ataattcttc gatagcaaat ggtttgacga tgtagtcatc
     2821 tgctccgtgg tcaagtccag atacacgatc gatcacagaa tctcttgcag tcatcataat
     2881 gattggtgta tttttgactt ggcgtacacg tctgcagact tctaaaccgt tcaattctgg
     2941 gagcatcaga tccaacaata tggcatccca ctcattattt aatgccgcat ctaaaccagt
     3001 tcggccgttg tagtggactt ctgcgttata cccttcatgc ttcaactcta gctcgacaaa
     3061 tcgtgccaag ttcttttcat cttcaatgat tagaatattg ctcatttatt attttatcct
     3121 ttctattcta ctggcttttt aaaaactcta tcattatacc gataatatgc ttaaaaatct
     3181 atagtcattt tatcatggat agcaatttta aaaaagagct gaagtctact cataacaatc
     3241 gacttcagct ctttcgtcct ctttttattt tctcatttcc taacagccga aagactatta
     3301 ttcttcatgg taccatgagt aatggaagat tccttctttg tcgacacgtt cataggtatg
     3361 tgcgccaaag taatcgcgtt gggcttggat tatatttgca ggcagacgtt ctgctctgta
     3421 tgaatcgaag taagcgatgg ctgatgagaa agtcggtaca ggtacgccag cttggacagc
     3481 caaggcaacg acgtctctga ctgattgctg atattttttc gtgatttcaa cgaagtaatc
     3541 atctagcaat aaattttcga tctcaggatt tttgtcatag gcatccgtaa ttttttgcaa
     3601 gaatcgagct cggatgatac atccagcgcg ccagattttt gcgatttcac caaatggcaa
     3661 gtcccaatca aattcttttg aagcgacacg taattgagca aatccttggg cataactcat
     3721 gattttactg aaatacaacg cttctcggat tttttcgacc aattcttttt tgtctcccgt
     3781 gaactcaaaa tcgttcgtac gagataaaat cttgcttgct tgtacgcgtt cttctttata
     3841 agcagaaata tagcgggcaa atacagattc agtgatcaat ggaagtggca cacctaagtc
     3901 aagcgcgctt tggcttgtcc atttacctgt tcctttattc ccagctgcat caaggatcac
     3961 atctactact ggtttacctg ttccttcatc gtctttacgt gtcagaatgt cagcagtgat
     4021 ttctatcaaa tagctgtcta attcgccttg attccattct ttaaagatat cagccatttc
     4081 ttctactgaa aggtttaaaa tattcttcat taagtcataa gattcagcaa tcagttgcat
     4141 atctccatac tcaataccgt tgtgtaccat tttcacataa tgtccggctc catttgggcc
     4201 aatatatgtg acacatggtg cttcgtcttc tgcttttgca gaaatttgct ctaagattgg
     4261 tgcaactagc gcataggctt ctttttgtcc accaggcatg attgaaggtc cttttaaagc
     4321 tccttcttca ccaccggaaa cgcctgtacc gataaagttg atgccagagt tggctaactc
     4381 ttcattacga cgcatcgtat ctttaaagaa tgtatttcct ccgtcaatca aaatatcgcc
     4441 tttatcaagg tgaggaagca actcttggat cgttgcatct gttgccggtc ctgctttgac
     4501 cattagcaag atccgacgtg gtttctcgat agattctaca aattcttcga ttgtatatgt
     4561 tgctttgaaa tttttatctg ggtgttcttc tactacagcg gttgttttag cccctgtacg
     4621 attgaataaa gccactgaat agccgcggct ttctatgttc aaggctagat ttttacccat
     4681 aacggccata ccgacaacgc cgatttgttg ttttgacata tgaactcctc ctacatacgg
     4741 gatttctccc taatctctta cattatagct taacacggct acattgcaaa ctaaagaaca
     4801 acatattttt tatttaccga ctacaaaaaa ataaacctca aggctccatg gttagccttg
     4861 aggttttaca ttttctaatt aaaatgtatt aagcttcttt tgacattacg tccttaccat
     4921 catagtaacc acaatttgca catacgtgat ggcttttttt catttcacca cagtttggac
     4981 attcgtttaa ccctttgatt gtcaatttgt agtgtgtacg acgttttgct tttttagctt
     5041 ttgatgttct tctagctggt actgccattt tgctacacct ccttgtaaag tcttgtatct
     5101 aaattagaca caatatattc caatcttact tgttatcgtc gtcttttgat ttagaatcaa
     5161 aaagttcaga tagttttgca agacgaggat caattttatt ctcggcttct tccatttttc
     5221 tgcgctggta ttcttcttcg gaaacaactt cccaatcatt gccttttgga agttctgttg
     5281 ctgcttcctc ttcttttgtc aatacccgca ttggaatcgc caataagatg ttgtcttcaa
     5341 tcgactctgc taaattcaat aatggacctt caattagcaa aatctcatcc gcagacattt
     5401 gttcatctct actttggaat tgttcttctg tcatgaatac ttcgtctaca gaaaaatcca
     5461 tgggcagttc aacaggttct agtgaacgtg ttgaaggaac tgtcaaagtc gtctgcacag
     5521 tgtaatgaac gatatagcct ttcttatcaa ctgagaccaa accttcgact tccactggcg
     5581 caacatcaag tattaaattg tctcgcttca tgagagcggc tttcaagtcg agcgtctcat
     5641 gaaaagttaa cggtgtctcc tggtattttc tcaattccaa taaagaccat ttcatttttc
     5701 atcactccta agcaacaaaa gcaattatac agggcaaaaa gcatgttgtc aatgaaattt
     5761 tcttgacacc ttgcagttca taaaaaaaca gaaaaatctt tattagaaag cctctgtttg
     5821 ctatcatcct cagaatcatt tacaataatc attattccat taaaggagcg gatgatcttc
     5881 atgaacacga aagatatcga atactatgtc caaatcgtca aacaaaaaaa ttttacgaaa
     5941 gtggctaatt atttccgtgt gagccaacct actattacat atgcattaca acgtcttgaa
     6001 aaagagtttg acaccgtact tattacaaga gatcgatcgc atcacgaatt aatcgtcacg
     6061 ccttctggaa agcagctgtt tctccatgca caaaccattc tccaagagat ttctactgca
     6121 agagctgaaa tcactcagtt gcaaaagaaa aagcttcgtt ttggcatgcc tcctattatc
     6181 ggcaatgaat actttcctaa actgtcaagt tactttatca agcatgaatt gatgaatcaa
     6241 attgagatta ccgatggagg ctctcgggac ttatacggga tgatccgaca agggaggatc
     6301 gatttagctg tattaggctc aacacagcca atcgtggatc aatatttaga aacagagtta
     6361 cttttggaca aacgtttcat gatcgtcgtg ccacctacac atcctctttc caagcaggat
     6421 actgtctctt tcaaagatat agcagatgaa cagtttgtac tattgaacga acattatgtc
     6481 caccccgcag cattcactaa gctttctaaa caaacacata ctcatccaaa agttgtttat
     6541 caaagcaatg acttgacgat tttaaagagt atggtccgag aaaatgtggg tatcggtttt
     6601 ttggcagaga ttgctgtcca tcctgaagat catttagttt gcctccctct ttcagatgaa
     6661 gttcagcctc gcttcttgat ttcattggca aaacgaacac agcagatcgt cacgcctctt
     6721 caagaacaag tagtccaagt tatccatgaa ttcgttacag cacaaaaaaa cagctcttcg
     6781 taaaagaaga gctgttttta ttttttatta agctaaatta gatagctgtt gtttcgccac
     6841 ggtaaacgat gccgcgacgt gaatcaacgg taatcaattc accttctgta attgttgttg
     6901 ttgcgccttt agcaccaacg attacaggaa tatcttgtgc aattcctaca actgcagcgt
     6961 gagaagtcaa tccgccttct tcaacgataa cagcagctgc tttttcgatt gcaggcatat
     7021 attctttgtc agttgatggt acaactagaa ccattccgtc ttttgctttt tttacagctt
     7081 cttcagcaga tgaagcaata actgcatttg caacgacaga tttttgtcca acgccttgag
     7141 cttctaataa tttagaacca atcatttgaa ttttcatcac gttagttgtt ccgcgttcac
     7201 caactggtac accagcagtg atcaagatta aatcgccttc tgatgcgaaa cctaattcaa
     7261 cagctttttt agctgctagt tcaaacattt catcagttgt tgatggtttt tcagcaactg
     7321 ttgggtaaac gccccagttt aacatcaaac cacgttttgt gcgttcgtca aaagtaacag
     7381 ccaagatatc tgcatctgga cgatattttg aaatcatttt tgcagtgtat cctgattcag
     7441 ttgcagcaac gattgttttc acgcctagat tttttgcagc acgagctaca gataaaccga
     7501 ttgtttcagt tacatctgtt ttatcgaatt cgttcaattg gaatgtacct aattctgata
     7561 atgcattttc agcttcttgg tcgatacgtg ccattgttga aacagcttca actgggtagt
     7621 ccccgtttgc agattcacca gatagcattg ttgcatctgt gccatcaaat acagcgttag
     7681 caacgtcaga agcttccgca cgtgttggac gtgggttttc ttgcattgat tctaacattt
     7741 gtgtagcagt gataactggg ataccagcag cattacattt tttgatgatg cgtttttgaa
     7801 ccattggtac tagttcagct gggatttcaa cacccatatc tccgcgggca atcataacac
     7861 cgtcagaaac tttgatgatt tcgtcaatgt tgtcgatacc ttcttgagat tcgattttag
     7921 ggaagatttg aacatgagtc atgtcttttt cttctaagat ttcgcggata tctagaacgt
     7981 cttgtgcttt acgtacaaaa cttgcagcga taaagtcgat atcgttgtct aaaccaaaac
     8041 gaatatcgtc agcatctttt ggagtaatac ctggcaaact aatagaaacg cctggtgcat
     8101 ttaccccttt acgtgatcct agcatacctg catttttaac ttctacgact aattcacggt
     8161 ttgcttcgtc tttttcaatg atttgcatat cgatcaaacc atcatcaaat aaaatgtgtc
     8221 cgccaacgtg aacatcgtca aataatcctg ggtaagtaac cgcgattttt tcttttgaac
     8281 ctacatgttc aggatccata gagatgcgtg tttgatctcc tacttcaaat ttgatgtatc
     8341 ctgcacgacc aaaatcagct tctgttgtgc cttgaacagt tgtacggatt tcagctcctt
     8401 ttgtatctaa aagaataccg acatcttttc ctgtcttttt aactgcttca cggaccatag
     8461 tcatacgtga taattgttct tcatggtcac catgagaaaa gttaaagcgg aagacatttg
     8521 ccccagattc aatcaattga gaaataattt ctactgagtt acttgctggt cctaatgtac
     8581 taacgatttt ggtttttttc atttaaaaaa ctctcccatt caattttgtt tatttaaagc
     8641 tgtacacagc ttaaatagct tggtttcttt cactcttaaa atgaaagtga attatttaga
     8701 tcatatagtg ataagtctgg tttatgtttg ttgttttcaa gtgtatcaat gatgtcagac
     8761 gcaacgattt cgttgtcatg gataccgaca cataatccac cttttccttc ttgaagcaat
     8821 tcgacagcgt aagcaccgaa tttacttgcc aacacgcggt cgcgtgcgct tggtgctcca
     8881 ccacggacaa cgtgtcccaa gatagataca cgtgtatgat agtcgccaaa ttctgaaagt
     8941 ttctcagcga attcatttcc gcccattaca ccttcagcca agatgatcaa gcaatgtttc
     9001 ttcccgcgat cgcggccttc ttggattttt ttagcaactg aagccatatc aaaatcatgt
     9061 tctgggatga tgatttcatc cgctccgcca gccacacctg accataaagc gatgtctcct
     9121 gcattgcgtc ccattacttc gataacgaat gtacgaacat gagaagtcgc tgtgtcacga
     9181 atacggtcaa ttgattctag tactgtattg attgctgtat caaaaccgat tgtgaaatca
     9241 gtcccaggaa tatcattatc gattgttcca ggaataccta ctgctgggaa accgcgtttt
     9301 gtcaaagcca ttgcgccatg ataagagccg tctcctccga taaccactag accttcgatt
     9361 ccgaattttt tcaattgttc gattcctttt aattgacctt cttcagttgc aaattctgga
     9421 taacgtgcag aatacaagaa tgtaccacca cgttggatct tgtcacctac atctgccaca
     9481 tcaagacgac gaatatctcc agcaactaaa ccggcaaaac cataattgat cccgtatact
     9541 tccagtcctt cgtaaatacc tttacgaaca acggcacgaa cagctgcatt cattccaggt
     9601 gcgtctccgc cactggtcaa aattccgatg cgtttcataa taaacattca cctcattaaa
     9661 atactttatc ctaagtatga cttaggttta caaccatttt tgcgttaacc acgactaaca
     9721 ttctaacatt atttttctca cttgtcttga tttacggata aaaaaatgaa aaaaaatgaa
     9781 agcaagtagt attttttacc gtaagttatt tgaaaaccac attatcttcg ccaagcagat
     9841 aaataagttg cccctttata ctcttgctgt catccaccca ataagcatct gacagaacta
     9901 cttttcgttg cgttttttcg tgatacataa ctactggtat atatcctggg tgtttctgaa
     9961 aaatcacttg taattgtttc attatctcgg gatcttcccg ttcttctgta atacgcaaat
    10021 agcaagtttg tgaaggatac tgggcttcta actggttagg atcagcaaag ctttctccaa
    10081 ttagttgcag ttcctgatta tatttgctga tttcgctccg cccttgaaca aagatcactc
    10141 gatcaacggc aaacaaatta cgatatttac gataaagagt tggaaaaact gtgacagaaa
    10201 tttctccact actgtcggtt ccttcaacaa aggccatcag ttctcctttt tttgtccgaa
    10261 tttctctaac ttccttgatc atcactaata aattgactgg ttgattaggg acgatatctg
    10321 taatcagctg aacttgttta gctaaacgaa gacgatcaaa cccttctgca ggatgacctg
    10381 acaaataaat acctaagtac tcctcttcca gcttcaagcg ttcttctagt gtatagtcag
    10441 cgacttcttc ttcttttaat gccatgattc ccagcaagtc aagacttcca ccactgtaaa
    10501 cgatattttg gatttttcct tcgagatcaa gcatcaattg tttcctgtta ggagataatt
    10561 catcaaaaac tcctactgct gtcagtgatt gcagtaactc taatttcagc caacgcttat
    10621 cgatccgtat gaggaattga tccactgact ggaacgggcc attttgtttt ctttcgttta
    10681 atatatcttc tacaaaatca cgccgaatac cttttatcgc tgtcagtccg aatctgattt
    10741 cttccttatt gaccaactca aaactggaat tactttgatt aatggacggc gaggaaagtt
    10801 tgagtttatt tttacgtgct tctgcaatat attctttcaa ttttgatgtg ttatgccgaa
    10861 cagaattcat caggctggta aagaaagcac ctggatgatg ggcttttaga tacgccattt
    10921 ggaatcccac gaatgaataa gcaaatgcat gtgaccgatt gaatccatag tttgcaaatt
    10981 tttcgatata ttcatatacg gtcgctgctg ttttttccga atatccctgt tgtaatgctc
    11041 ctgatacaaa atgcgacttt tcttcatcta atacgtcttt tttcttttta ctcactgccc
    11101 gtcgcagaat atctgactgc cctaatgtaa atccagccat agtcgaggcg atctgcatga
    11161 tttgttcctg atagacgatc actccatatg tgtttttcaa aatcgggatc agtgaatcat
    11221 ctgggtagcg aatggcttct tttcctttct tcctggcaat gaaggtatct atattttgca
    11281 tagggcctgg tcgatacaat gcattgactg cggcaatatc ttcgatgttt tctggatcta
    11341 atcttcgtaa aacgttccgg ataccagcag attcaaattg aaatactcct gaggtttcgc
    11401 ctcgttgaaa caagagcagc gtttttgcat catttagcgg gatctctttt aatcggatct
    11461 catacccttc tactcgctta acagctttca aagtaaaatc aataatcgat aagttgcgta
    11521 gtcctaaaaa gtccattttc aaaagaccga ttgcttctac ctcattcatc gtatactggg
    11581 tcagaaaagc ttcatcagaa ccgcgttgga gcggaactag ttcaagtaga ttcttatcgc
    11641 tgataactac acctgctgcg tgagtcgaaa catgtcttgg caatccttct aaaatcactg
    11701 cagttttgaa taaaagttgg tttttttcgc ttgcctgaac taattctact aattgatgcg
    11761 aagttttata agcttgggtc aatgtgattt tcaattgatt gggtattgct tttgaccagc
    11821 ggtttgcttc actttgcgat aaaccaaaca ctctagctgc atctctaaga accatttttg
    11881 ctgccattgt gccaaatgtt gcgatttgtg ccatatgata ttgtccatac ttttctcgaa
    11941 cataattcaa tacttcttca cgtcgattgt caggaatatc caaatcgata tctggcatcg
    12001 taaagcgttc ggggtttaaa aagcgttcga acagcaaatc atattctaat ggatccacat
    12061 ctgtgatttc taacacatag gctactaatg aacccgcagc agaaccacga cctgcaccgg
    12121 taacgatttt gtttctatga gcaaaagcca ttacatccca tacgatcaag aaataatcat
    12181 cgaatcccat ttgatggatg acagataact cgtagtccaa acgttcttgg tattcctttg
    12241 tatagtcagt gattcggcgt tccacttgcg aatagcataa ctctcttaaa tattctccag
    12301 cttgttttcc attaggaact ggataatgcg gaagtaattt ctgatggaac tggaattcaa
    12361 atgaaatcga ttcagctaaa cgctgggcgc ctattacagc ttgggaaaga cccgcttttt
    12421 cgaatcgttt gatcatttct tgttctgaaa gaagatagac atttgctgtt agtggtaaag
    12481 atgcagataa attttctaaa ggtatttggc ttccctcttt gatatgtttc atcacttcaa
    12541 gtgcaaaaag ttcttcttgt tgtaaactag cgatgggatg taatgcacaa agcgaataat
    12601 tttcttttat cacatactga taccattcag gcaattgatc aggcgtgttt tctgtcaagc
    12661 cgatataaaa atttctagta aaaacatttt caagtaaaaa ctgccaatga ccgaaaaagt
    12721 tatcctcttt attgaaagcc tcagaaacag aatgatttgc cggaacaaca aacgctagat
    12781 ggtcggtttc tgtcatttct gcaagttcca atttttcttg gatcattttt cggctggaaa
    12841 gtttcatcag ctgctgataa cctatttcat cttttgcgta cgcaagcaag ccataatttt
    12901 tttcttcata agtataacta agatgtaatc caatgattgg ctgtactcct tcttctacac
    12961 aaatacgata gaattcaggt gcaccgtata agacatcttt atccgttatg gctaatgaag
    13021 tgtagccttg tttttttgct tcttgtacat attctcgaat acgtatcgta ctttgtaaaa
    13081 gagaataaga agtaattgta taaagttgtg ggaaaaacat cttgcattcc gccttttttt
    13141 tcgttaaaat tcactagcgt taaaaggttt gatcctttta ctttcattaa gatagcaggc
    13201 gctgaagttg attattccac ttcatttgct tgcttgtaat ctgtaggaat gagttctttc
    13261 gcaagaactc aaattttatt gagatttggt ctcgtttctt tacattcaaa gaaaatctgg
    13321 taaaattaag atagaaaaga ggtgttcttt atgcgatata tcgttacatt attctgggct
    13381 gtcgttctag gtcaagtagt cggttatatt ggtgctgcat taacaagcgg aacatatgat
    13441 tttactttga caacaatcat ttcattcatt gcgggtgtca ttatcctttt gattggtgca
    13501 gttgcgccaa gaaaagaaac ctctgcccat tcgtaaaaaa acagccaaga gcttgagatt
    13561 tctcaagctc ttttttattt tctactcctc accaccatta taatctgctg cgaagaactt
    13621 tacgaaagtt gaataaagaa agaagaatat ttgacagaac aaacaaactt gtcacaataa
    13681 aaacagcact gtaattataa gcatgcgcga ctgtcgatcc tagcatggga cctaaaactt
    13741 gtccaaagtt gctaaacatc tgattgtagc tatagattcg gctgactcct tcttgaggcg
    13801 taatcttact gatcagtgta ttgacagaag gcatcaaagc gccagttgaa aagcctaaaa
    13861 taaagcgaag tatacctaat tggagcggtg tagtgacgaa tgccataggt aaataacagc
    13921 aaaatgataa aatgagtcct ccaattagaa ctttttgatt cccaatctta tcccctagtt
    13981 ttcctagttt cggtgaagaa aagacagcgg aaacaccagc tatcgaaaca atcaagccgc
    14041 tgacaaaaag gatattttct gtacttccgc tcaattcacg aatatataag gtcaaaatag
    14101 ggctgatcgt agtgattcct atctgtaaaa tcaaggtcgt aatgaagaga ccgatcaaaa
    14161 tagagagatg atccattttt gaaaaaattt ctttggtgct tatcagatct tttttctcga
    14221 ttggatggaa atcttctttg actaagaaaa tggtcaatac cgttgtgatc atcaacaaag
    14281 cccctgtgat caagaataca ttttccatac caaaccactg agccagtgca ccgcccattg
    14341 aaggtccgat cagatttcca gcaatcgctc cggtagacaa tgttcctaac gcccatccgc
    14401 tcttttctct aggtgcctgt gaagcaatca tcgctgtggc atttggaata tatccagaca
    14461 aaatcccatt ccaaaaccgc atgatcaaaa gccaatacgc gtttggtaca aaagccaaag
    14521 atcccattgt taatgtcatc cctgctgctg cacggatcat catgagtttt cggccttttc
    14581 gatcagctag atttccccag attggtgcaa ccacggcaga tgcaaaagca gtcacagaga
    14641 ttgctagtcc cgaaaacaat tcgatttgat cttttggtgt tcctagttgc tcaacataaa
    14701 ctggtatgaa tggcataact aaactaatac ttgcaccagt gaaaaaacag ccaatccacg
    14761 caatcactaa attttttctc caattaatct ccatctatca tccctctttc gtctctttta
    14821 tcatacctat tttcgaataa acaagcaacg atctcgccag taaaaagaga aaaatcccgc
    14881 aaaggtcatt ttatatgtaa cgttcttttt atgtaaaaca aaaagagatc agaacaaata
    14941 ctgttccaat cccttctctt tagttaaatt gttgctagaa tgatgaagtt gataatgaat
    15001 aaaatatcaa cgatccacaa agcaacagaa acttgattgt attttccttt gattactttc
    15061 acaattgtat agaaaataaa tcctgctgca atcccatagg aaatgctata gcacaatccc
    15121 ataaagatcg atgcaaagaa ggccggtaaa gcttcttcca tatctagcca tttgatgtct
    15181 gcaaaagaag ccatcatcat tactccaact aaaatcaatg ctggcgcagt tgcttgattt
    15241 ggtacaatgg cgatcagtgg agagaataaa ctacttaatg cgaatagcac tgccactact
    15301 actgaagtca aaccagtacg tccaccggcc ccgatcccag ctgcagattc gacataagtt
    15361 gttgtattcg atgtaccaaa gatagccccc acagaagtag cgatcgcatc ggcaaatagt
    15421 gctttatcca tttttgtttt gaacccacga ccatcttcca acgcgatctc gtcttctttt
    15481 gagaaaatac ctgtgcggcg tcctgtaccg ataaatgttc cgatcgtatc gaaagtatca
    15541 gataaactga atgcgatgat cgtcatcaat acttgaggaa tcttggaaga atcactgaat
    15601 aaagattgca tgccttcaga accaaatgct gcaccgaaag ttgttcctaa ttctttaaat
    15661 gaattaccta acgaattcgt ttgccaatca atggaactta aatcaacaac acccataaaa
    15721 ataccaagga ctgtggtcgc tacgataccg ataagaatag ccccacggac attttttaca
    15781 actaaaatgg ctgtcagtac caaaccaatc acagccaata agataggagc gttgtcaaag
    15841 ttggctaacg cagggacgat tccaccattt atcgtaacat ttgtcgcttt tccgccttca
    15901 acgacagagc tcgaaatagc tgactggtct gctgaaaaag ataagaatcc tgcatttttg
    15961 attccgacat acgcaacgaa aataccgatc ccgccaccaa tcgcatgttg aagactttcg
    16021 ggaatcgccc gaataatcat ttttcgaata tttgtgacag taataaaaat attgattaat
    16081 ccgcaaataa acaccattgc caaggcttgt tgccaagaat aaccaagccc aaaaacgacc
    16141 gtaaaagtga aaaatgcgtt caatcccata ccaggtgcct gagcatatgg tacatttgcg
    16201 aacaatccca ttaccagcgt accaataatc gatgcaatga ttgtcgctag aaatactgct
    16261 tggaagggca tacctgatgc tgacaaaatc gtcggattta cgaataagat ataactcatg
    16321 gcaaagaatg tcgttactcc cgccattatt tcagttgata catttgtatt gtttttcttt
    16381 aaaccgaaaa acttttccat aaaaagttcc actccctgaa tttttttctg atggaaaact
    16441 ataataataa aaaataagta aaatagggca aatccatcga acaatttcaa attatataga
    16501 cgtttcattc gcttttcaac gtttttttaa caaaaaaagc gaaaataata cttaacgttc
    16561 gtgtttagct tatgtttagc tatttatata gccataactg tagtttttgt taggaatagc
    16621 tgattgctct tgttaattac ctaaaatatg ctagactaaa acaaatgcta gttgaggaag
    16681 gaaggaccct tattgaataa aaaattaatt gccatcgatc tggacggaac taccctcaat
    16741 caagattcga tgattacatc taaaacaaaa gagactctaa aaaaagcaat caatgccggt
    16801 catcatgtca gtattgctac aggacgccca ttccgaatga gccatcagtt ttaccaacaa
    16861 ttagaattaa caacaccgat ggttaatttt aacggcgcat tagtacacat ccctaatcag
    16921 cactgggatg gtgaaagaga aacgttgatc aatcgtgaaa tcgcttttga aatcttatcg
    16981 caaaaaaagc agctaaattt agattttatc gctgctgaaa atcgtgatac tttttttatt
    17041 gacagttttg atttctttga tgaaaaaatt tttgcttctt ctcgtccagg agagaagaat
    17101 ttgctttctc ctaaaaattt gacgacaaat cctacatctt tgcttgtccg aacagacaaa
    17161 cgttttgcag gagctgtatc tgctgaatta acacgtcaat ttggcagtta tgtcgatgtt
    17221 cggacatggg gtggacctac tgccatctta gagattgttt caaaaggaat ccaaaaagca
    17281 aaaggcgtgc aagagattgc taactacctg tctatcgatc aaaaagacgt cattgccttt
    17341 ggtgacgagc ataatgattt ggaattgttg gattatgcag gttggggagt agctatggct
    17401 aacggtactg accaactcaa aggcattgca aatgatgtca ctcctttgag caatcaggaa
    17461 gacggtttag ctgtttatct ggaaaaacta cttaaactat aatagagaat tagattccac
    17521 aaaaaagagg ttgtgacaat ttttgtcaca accttttttg ccgagtaaac ggtgttcaaa
    17581 agccagtttc tcggtatgaa gtcaaattta agcaaaaatg tgagaagcta ttttcacaaa
    17641 atttttcttc atactcgaaa ctaagcggct ttttcacgac ctctttttta ttttgccatg
    17701 aacatatcat aatacgcgtc cattatttct ttagcaatcg tcaagtttat gtggtcttgt
    17761 tcgtctaata agttcggcaa gacaacactg atggcaattt ccggattgtc tgttggtccg
    17821 tatgccacga tattactatt gactgtcgca atatctggat gaccttccgc aaccgtttct
    17881 gcagtccctg tttttgcgga aaggtccatt ttcgcactgg ctaatggttt ggctgttgtg
    17941 taaggatcgg taccatggac aacttggtgg aatccttcac ggaggatcgc catattttct
    18001 gcagaaatat tgaccgtatt ttctactgtt gtgccaattt ctttcttcac ttcacccaag
    18061 tttccatttt cgtcattgcc atagatcgct ttgactaggt gcggctgtac tcgtttcccg
    18121 ccattagcga ctgttgaagc atattgagct aattggattg gtgtatatgt gtcaaactgt
    18181 ccaaatgcca aatcggtaaa gttacctgga gcataccatt ctttgccatt atccgcattg
    18241 aacttcttca tataatcaac agaacgtgag atcccaggag attcattcgg caaatcgatc
    18301 ccagtcgttg taccaagacc aaactctttg aaagagtctc tcaattgctg ataagcttta
    18361 gcttcttcat ctaaactagg tagtcccatt ccaggtgtat agtctagtcc taacatcttt
    18421 aacgccactt tgatcatata cgtattagaa gacaattccg atgctttgac tgcatcaaga
    18481 gcaacttgtc cgcttcgatt aaagacagag cttttttctg aagcaccttg cagacgaatc
    18541 ggctcatcaa tcaaaacttg atttccgctg atcgcgttac ttgcccagcc tgctgtcaaa
    18601 gtaccagcct tgactacaga ccctggatca aaggcgctag taatcgtgcc taaagcattc
    18661 tcggtgattt ctttggaacc ttgttcatga ctgaaaccag tcattgctag cacttctcct
    18721 gtctgaggat tcatagccac tgcataagca ccaggcgaat actgtgcttt gccgttgttg
    18781 atcaatgttt gataattcct tttcaaaatt tcttctactt ttgattggaa ttctgcattc
    18841 atagataaca ttaaattaga acctttttcc ccagagaaga tttctttttg attcgaaaca
    18901 tttccttcat tatcaaggga aacttcatat tgggttttgg ttccttgcag gacatcttca
    18961 tattgttttt ccaaataact ttgtcctaca cggtcattcc gagaataacc ttttgctagg
    19021 tatttctctg cttcatctgc tggaagtcct tgcttttcag tcgtcacact gccaagaata
    19081 cttttcagtg aacttgctgc attatattct cgtgtccagt ctgtgccagt cgaaactcct
    19141 ggaagttcag aagcgcgttc tgccacaaca gctaactctt gatcagtaac accagagttt
    19201 ttgatataga cagtgtttaa ttcatatgca ctattcatcc gtttaaagat ggtagcaatt
    19261 tttaattgct cctcgtttaa attaatctca tcagctgtga ctttattgac catcgcacta
    19321 tattgttcgc tgttccctaa ttgcttttct tttgccgaaa gtctttttgt ggcttctttc
    19381 aaatgtttgg gatcagccag ccaaaaatct tttttatctc tatctgtcag attttcatct
    19441 accggaacat cgatcagcga gttcagcttc gttgcgattt caagcaaatc tttagccgta
    19501 acttgtgttc ctctcgtata tgtgatggcc tgattcgctt tattcgtaac taaagctttt
    19561 cctgtggagt cgtagatcat tccgcgagga gtactttctt ggaccgtaat cttagaagta
    19621 gacttcactc gcgcctccat ctcttcgccg ttcacgatct gcaaataacc caatctagca
    19681 atcaacgcaa caaataacgt aaatataatg aaaaaaagaa aatttaagcg aaaaggaaca
    19741 tgggaccggc gaaacgtttt gttcttaggt tcttgtgcac cttttcttat tttttctaac
    19801 caagaagtat ttaatatttt tttcataaaa tctttcatca tttcctatcc ttccgcctat
    19861 ttacattcat gcttcattgt acccaaaaac ttcttaataa acaagaagta tttaatattt
    19921 ttttcataaa atctttcatc atttcctatc cttccgccta tttacattca tgcttcattg
    19981 tacccaaaaa cttcttaata aaaaagaaaa aatgggcgga gcaagaaatt ctttacctaa
    20041 tttcaagata aaatcaactt tttgtttcac agcaatcact taaagttaca tatccaacta
    20101 tttttttcat taaaaaataa acttattttt gaaaattatg ttttcttaag tcgtgaaaca
    20161 ctttgatgga tcatttattt gtggaaaact acgttttgtt attctaaaaa acttatataa
    20221 aaaatagtaa ggtttttatt tcgaatccat aaaatattct tggattgctt ctcgtgtttt
    20281 tttcactttt tcgctaagct tttcgttttt agccatatag aaataaaaaa tgatatcgat
    20341 cgtagcaaat tgggccaaaa gtgaattagt tgccgcactt cgattcgtga tttcttttgg
    20401 tctagatgtt tgtacgagta catcggctat cttgctaagc gggttatttc caaattgcgt
    20461 caacgcaatg atttcgatat tcatgctttt cgccagctcg gctaatgcga ctacatctgc
    20521 acttctacct gagtttgaaa caagccaaag cactttcttt ttctcattgc tgacaagttg
    20581 cgggagcaag acgtggatat ctttttcaaa aatgattggc ttaccgacac gagaccattt
    20641 ttgcagaata tcttctacta ctaaagaaga ggcgccaacc ccatataaaa aaacagtctc
    20701 tgccgattcc aaacactcta cgactttttg gatcgtttct tcttctagaa tatctactgt
    20761 ttcttttatc gctacttgtg cattgttacc aagtttgttt ttgatagagt aaaaggactc
    20821 atttgcttct atatcactaa aaccttcatc gattccagtc tgtagttctg ttgaaatcgt
    20881 gattttgaag tccgtcagac tttgaaaacc gatttttttg gaaaaacgta caactgtcgg
    20941 cgcactcaac ccggaagctt ctgctaattc attagctgtc attgtaggga ccttctcaat
    21001 attaccgata atgtagttgg ccaacttttt ttctgctgaa gaataatctt ccatcatact
    21061 ttcaatacga ctaattacgc tcataagttc ctccaccctt ttaatgatag tctatgtaag
    21121 tataccatat cagaccctta ttcacggtcg tatactggat aaaaaacaaa aaaacaatcc
    21181 gcccaacaga atatcttatc ccatcaatcc cacagattct attgagcatc tgtgtctttg
    21241 aggaatacct gttatctatt gttcggattg ctttctatct actacttttt tacaggaaat
    21301 ttacctatta gttttctctg ctgtaatttt tgacttctgc ttccatagca tcaataaaga
    21361 tattcaaatc ttctacagct gtttctttac ttccataacg acgtacgttc actgttgcat
    21421 cttccaattc cttgtctcca acaactaatt ggtaagggat cttttgtgtt tgagaggcac
    21481 gtatcttata gcccattttt tcattacgat catcaacttc tacacgcaac cccttcattt
    21541 gcaaacgttc tttgatttca taagcataat cgccatgtgc atcaacagaa acagggatga
    21601 ttgttgcttg tataggtgcc aaccatgttg gaaaagcgcc tttgtatact tctgttaaat
    21661 aagcgacaaa acgttccatt gtagaaacaa ttccgcggtg gataactact ggacgatgcg
    21721 tattttcccc gtcttctcca acatgtgtca aatcaaagcg ctctggcaat aagaagtcta
    21781 attgtatagt tgataatgtt tcttctgtac caagagctgt tttgacttga acatctagtt
    21841 ttggtccgta aaaggctgcc tcgccttctg cttcaaagta atctagttct aattcatcca
    21901 tagcggcttt cagcattgct tgggcttttt cccacattgc gtcatcatca aaatatttat
    21961 ctgtattgtt tggatcgcga tagctcaagc ggaaacgata atctgtaata ttgaagtcag
    22021 catatactgc caccatcaat tcaagcgtac gtttaaattc atctttgatt tgatcaggac
    22081 gaacaaatgt atgaccatca ttcaacgtca tttctcgtac acgttgtaaa cctgacaaag
    22141 cacctgattt ttcatagcga tgcatcattc ctaattcagc gatacgaatt ggtaattcac
    22201 gataagaatg gatcgtgttt ttgtagacca tcatgtgatg agggcagttc attgggcgaa
    22261 gaacaagcat ttcgccatct cccatatcca ttggcgggaa catgtcttct tgataatgat
    22321 cccagtgtcc agatgttttg tacaactcaa catctcccat tattggtgta tatacatgtt
    22381 ggtaacctag actaacttct ttgtctacga tataacgttc gatcgtgcgt cggattgttg
    22441 ccccttttgg aagccagaat ggcaaaccag aacctacttc tggggaaacc atgaacaagt
    22501 caagttcttt tcctagttta cgatggtctc tttcttttgc ttcttcacgg agacggatat
    22561 attctttcaa agctttcttg tcaaaaaagg ctgtcccgta tacacgttgc atcatttgat
    22621 tgtttgagtt tccacgccaa taagcacctg ccactgataa taatttaaat acttgtatac
    22681 ggccagtgga tggaacatgt ggtccacgac acaaatcgat gaattcgcct tgttgataag
    22741 cagtaatcac ttcttcttct ggcaattcac taatcagttc tactttgtac ggatcacttg
    22801 caaaaatttc taatgcttcc tgttttgaaa gaacacggcg ttcgatcggc agattttctt
    22861 tgacgatttt catcatttct gcttcgattg ccggcaaatc ttctgcagtt acttggtttt
    22921 gtccattatc tgtatcgtag taaaaccctg aatcgatagc tggtccaacg ccaaagtgga
    22981 tatttggata gaggcgacgc atggcttggg ccatcaaatg agctgctgaa tgacggacta
    23041 agccaagtgc atcttcatgg tctggtgtga tgatctcaat acttgcatct tcctcgattg
    23101 gacgagtcaa atcaacgagt tttccgttca ctttaccagc taaagctttt tttgctaagc
    23161 tttttgaaat gctttcagca attgccaatg ttgttgttcc agactcaaat tctttgactg
    23221 caccatctgg aaaagtaatt tttatcataa tagtttcctc cttgaaatgt tttgattgat
    23281 cagatcatca agctgaaaaa caaaaaaatc ctagcatctc ttgaaaagag atactaggac
    23341 gaaaagttcg tggttccacc taatgttcaa acgcaaatgc gttcctcaag cgttgtaacg
    23401 gtccgaccgc ccttgcttca acaagggttt cgaaagtggt catcctttgg ttttctcctg
    23461 gaaaagtttc agcctagctt ttcctctctt atcgaagact ctcaaattca gttggctttc
    23521 tcatcaatca attatgtgtt tatttaacca ctaataaata gaaaaatcaa gtgggaaact
    23581 aaacttattt tttccattcc ccatttacac cgtatgttcc ttttttcatc tcattgatga
    23641 tgacatggat gtgttctttt ggtgcctgcg tgtttttatg aacagcttcc gtgatatctt
    23701 tcatcatatt ttctaattgt tccggactgc gaccttctac taattcgaca tgtacgaatg
    23761 gcataatgct ctctcctctt tctgatcgtt cttttttcaa ctcgattcta tcatactatg
    23821 tttgtcttgg gtactgaatc aggaaaaatg gctggatctt tttttgctct caaggcactc
    23881 aaaatagaga ccgtatccac gacttcttgc aaaacagctc cgaataatgc ggggattagt
    23941 cccgtacttg caattaacat caaaaaaata caaataaaga tgccaatcag tacagactgt
    24001 ttcgctattc tcatcgtatc tcttgaaatc actactgctt ttgctacacg caagagatca
    24061 tctttcaaga tgaccgcatc tgcactttca ctagcagctg tagaaccatg agcccccatt
    24121 gcaataccga tatctgcagc agcaagtgct ggtgcgtcat tcacgccgtc tcctaccatc
    24181 gcaacaggtc tttgatcttt agggatactt tctaaaatgg tcagtttatc ttgaggcaag
    24241 ctacgggcat gtacagaatc taattggact ttttctgcaa tcgtttgagc aatggcagat
    24301 ccatccccgg tgatcatcat caaatttttc acatcaagtt ttcttagctc cttgattgtc
    24361 tttgctgctt ctgggcgaat ctgatccgaa aataggatcg ttcctgcaaa agatcgatca
    24421 attgttacat agattgctgt attggacgtt tctatttctt cagctgaaac aaaagaggca
    24481 cgtccaatct ttacttcatg attattgact actgcttgga ttccttgacc ggtcacttct
    24541 ttcagttgac taacaggata cagttggctg tttttcacgt tgttcactaa cgaacgagct
    24601 aagatatggc tagattcctg ttctgcacta gctgcataca gaagtagctc ttcttttttt
    24661 attccattga ctggctgaat cgcctctact tccaatatcc ctttggtaag cgttcctgtt
    24721 ttatcaaaag caatcgtttt tgtacgtgcg agcttttcaa tcgttgttcc agtttttaca
    24781 acgatcccgt ttttacttga acggctcatt cctgcaacta aagcaatggg cgcagctaga
    24841 atcagtggac aaggtgatgc cactaccagt acctcagcaa atcgtaaagg gtcttttgag
    24901 aaccaccaag aaataccacc gatcaaataa gcaatcaacg tgaaagggac tgcataacga
    24961 tcagctaaac ggacaaatcg ggcaggcttt tcttttgatt cttcgactag tttaataatc
    25021 atttgatact ggctgtctgc ggcacgtttt tcagcgatca tttggatcga tccgtctcca
    25081 tttaaagacc ctgacataat ctgatctcca ggtttcttgg tttccgggcg ggactcacct
    25141 gtcaaagaag attcatcgac cgaagattct cctttggtca ctcgaccatc tgcgggtaca
    25201 agttcgccag gcttgactag taactggtca tcaatattta tttcatcgat tactatatcc
    25261 tgcaattttc cttctttgaa tcgatgggca attcttgggg tgttatctaa caaagactgc
    25321 agttctttac ccgctcgttt attcgcgtaa tcctctagac tatctccgcc cgtaagcatg
    25381 atcaatatca tcaaactagc ccagtattct ttgacggcta atgttgcaag gattgcggta
    25441 atcgctaata catctacgcc atatcttcct gaacgtaacg tcttgatcat ttccaaaaac
    25501 atcaagaagg cgagaatccc tccagtaaat gcgacaatcg caaatgcaag ggccggctgg
    25561 tgaaaaacaa attcacttaa taaagctatc ccaccaataa gcaaagtaag taaaaatttt
    25621 ttgaaatgtg tcattgtttt ttctcctctt ttatgtgact tagagaggtt agtaataaat
    25681 ttccagctgc ctctttcatc ttaagcatag tccttgacta gcacttttta aaacaatagg
    25741 ccttaattga aaacaactat cactatcagc gtttccaaaa ttcatcagtt ctacaaacaa
    25801 aaatattcag caaggattac tttttcgatt catcagttaa aaagtacctt ttttcgaaaa
    25861 actatgctat acttttaatt cgttatttac ggcggaagga gcaaacatgc gatgaatgag
    25921 aaacaactag aacaaacgca cgtggatgaa acgatcgaac taatccagat cgaacaaaat
    25981 atgctggata caaaacaaca agaattgact caggaaatga atcattcgac aaaagacaca
    26041 gctaatcaca agattcgagc tggttccaat gaagcttttt atgaatctgc tgttgaatat
    26101 cgccaacatg agcaggaatt gcttttgaaa taccatactc ttgaagcaca gcaaaaacgc
    26161 ctgcaaacgt tgtctgtcat gaaagatagt ccttattttg cccgtatcga ctttaaagaa
    26221 gaccgtgaaa cagaaacatt atatctaggt atcgcttctt taagagatct ggcagaagaa
    26281 acaatcgtta ttgactggcg cgcaccaatt gccaatcttt attatgaagg tgagattggt
    26341 cccgcatttt atgaaactga aacagataga atagatgtcg atctgcagtt gaaacgacaa
    26401 tttaaaatcc aagaaggacg tattttatct atggtagata cgtcggaagt aatcaatgat
    26461 gactttttgc tagagatatt ggatgaatca tcaagcaacc atatgaaaaa catcgtctct
    26521 acgatacaaa aagcacaaaa tgcaatcatt cgggacacaa caagtaaagt aatgctgatt
    26581 gaaggaatcg ccggaagtgg aaagacatcc gctttgcttc aacgtattgc ttttctgttg
    26641 tatcataatc gcaagtggct cgaggctgaa aacgttcttc tattttcacc caaccatttg
    26701 ttttctgatt acatctcgac tgtattgcct tcattaggtg aaagcggcgt gcctacacag
    26761 acattcaaaa attatttggt gcagctgctg ccagagtttt ctttactaga tgaacagcaa
    26821 caagaaagtg gttttttgct aggggaaaaa gatccgatac aagtgatgaa aagcggattg
    26881 accttagtcg atcagattga tcgctatatc caaggcatca caaactacgg tcccttgttc
    26941 cgtgatatga aaataaatgg ccgtacgatc ctatcaaagg aatcgattcg ccaatggtat
    27001 aaagaaacaa atgaacaatt acctttacat catagacttt ctctattaca aacgaagctc
    27061 ctgaaaaaat taggcggtct gcaaaaagac gaaacacgtc agcaatgggt caaagatctg
    27121 gcggaagaac agctccaaga actatacgca acagatccaa atcttgaata tacagaacaa
    27181 aaggagcgtt cattacgtaa aaaactggcc aaccaaatcg tacgtaaaag attccgtcga
    27241 atccatcgag ggatcatgaa ttatcaattt gtcaatataa cgaaacaata tctccacttt
    27301 ctacaaactg tgccactttc tcttctaaca cgacataaaa tcagcgagac caggtggcag
    27361 gaacatttga caactgttcg tacacacttg cgtcaaagag aattgcgtca agaggatgct
    27421 gtactattct ttttactgat gcgccgaaca tatccagtga cggttacaca caaagctcgc
    27481 tatatcttta ttgatgaaat gcaggatttc gcaccatcac aagtggcatt gctgcaagcc
    27541 ttgttcccaa aagcaaattt gactttctgt ggagatctaa atcaaaatgt ctttggaaat
    27601 gaaacgatcg ttggatcatt ggaagacctt ttcgtggacc gtgaagtcac tcgtttccaa
    27661 ttaacgacaa gctatcgctc cacaaaagaa atcactgatt ttgctaatca ttttattgtg
    27721 aaagaacatc aagtagaaac aacagcaaga aaaggagacc ttcctttgct catccaagga
    27781 acaacagatg atatcaaatt gaattggtta gcagatacca ttcgaacgac tcagggaaaa
    27841 gcccggtatt ggcgtacagc aatcatagct aaaacacaag aagaatgcga agctctttat
    27901 gctcaactgc cagacgagtt gaaacaacaa gtccagctga ttttaaatga gagtgacttt
    27961 atgaagcgtt ccattatttt acttccagcc tttttagcaa aaggtctgga gtttgaccga
    28021 gttttcttgt gggatgtaga tgcagaacat ttttcttctc agcaagacaa attgatcctt
    28081 tacaccatgt gtacacgtgc gatgcatgaa ttgacccttt ttacctccaa taatgaaagt
    28141 cctttgttaa acaatatgga tatttcatct tatgagaaaa aagtactgta agtaaaaaga
    28201 caactgctat cattaatgtt agcagttgtc tttttattta caataataat tgcagaaaaa
    28261 gtaattcaat catttaaggt catttattct atatataaat ccaaatctgt ttcaggatat
    28321 tttaatttga caagcgaaat aatcattttc agttcttcca tgttttctgg atattctggg
    28381 tcaaatacct tgctatgacg gccaatcccg ccattgtcga tcaatcggta aattcgattc
    28441 cattcaatga attggtcaat tgattggaaa ttgctgattg gatagccgcc acaatccaaa
    28501 atctctgata cacgaaatgc taggtatgca ctatcgatca ctttattttt tttcgtgtct
    28561 atcttctcat ttctttcgat aagaattttt tcaggacgat gtttcaagct ccactctaat
    28621 agtagaaaga aagcctccat ccgatactct tcttcaaata accgaaaggc tgaatcagaa
    28681 cgacgaaaaa gcagcggaat cagataattt tgtctataaa tcagcattgg tgcgcggtcc
    28741 accatacact ctaaataacg gttcagatac cctgtaccga catagtttcc taatcgatag
    28801 ccttcaacgc cgaatcttgc gtatttttgc gctaattttg aacaatcagt tacgttcaca
    28861 gctaactctt ctactttgcg gtaaccgctt aagatacgtt caaaaggttc taaagtgatt
    28921 tttgcttcca tattcttccc cgtccatctt ccacatactt catatcattt cacatgatac
    28981 ttatgctctc atcataccac aggttgaatt agaaaagaaa ataaatcaca caaaaaagca
    29041 agacaatctg ttagtgagat tgtcttgctt ttcgaaaaag actgaatact tttcgttaaa
    29101 actggttgct tagtcttcta atgccacatt atggaacaca tgctgtacat cttctagatc
    29161 ttccagtgca tcaatcattt tttcaaatgt ttcttgatct tctggagata gtgttacctc
    29221 gttttgaggg atcatttgga tctcagcgat tgaaaaatca gtgattcctt tttcttttaa
    29281 tgcttcttgt atactatgga aatccgctac ttcaccgtaa acgatgattt gtccttcttc
    29341 ttccattaca tcgcgaacat cgatgtcttt ttccattagg tattcaagga tctcgtcagc
    29401 gtcttctcct gcaaaagcaa agattgctgt attgtcaaac atgtaagaaa ccgctccgga
    29461 aacacccatg ttcccgccat ttttcccaaa tgctgcccgt acgtctgctg ctgttcgatt
    29521 cacattgttc gtcaatgtat caacaatcac cattgagccg cttggtccaa atccttcata
    29581 gcgcaattca gagtatgttt catctcctgc accttttgct ttttcgattg ctcggtcaat
    29641 aatatgtttt ggtacattat aagttttagc gcgatcaatg acgaaacgta gtttttggtt
    29701 tgcatgcgga tcaggatcac ctgattttgc tgccgcgtag atttcaatcc caaattttgc
    29761 ataaatccgg ctattattag catctttagc agttttcttt gctacgatat ttgcccattt
    29821 acgtcccata ttttcacttc gctttctgat ttgatagttt cataacgcaa aaacgtcctg
    29881 ttccattata cttgtgaatc acgattctgt gaagcttttt ttctttcttc cttcattctt
    29941 ctcattttta gtcaattatc tatactcgga ttgggatttg cccgaaattc tgttccggaa
    30001 tattgcctcc caattgatag atttgatcac ttctaactaa cagttccgct tcttgtgcct
    30061 ctttttttcc gattcgggaa taaatagaaa tctctttttt ttcttttaag aatcttcttc
    30121 cagcatcggt aaatccaagt agtcgaagat aatttttatt ttgttggaca ggaatctctt
    30181 gctttttgat attcagcaag acataacaag ataatcgttg gatccgtgtc catgtatatc
    30241 tttttgtttt tacctttgac acaaaatcct caaaactatc agcagttgca gctgctgttt
    30301 tcatgcgcga ttctattcct tcggtcatct gatagatatc tgtcagttcc agcaaagtag
    30361 aagataacaa ccgataacgc aaatacggcc aataagattc ccaagtctgc agcgaacaag
    30421 ttgaaagatc ttcttctgtc tgaggcggca caagtccagc tattcttttt ccttcttcta
    30481 acgcatggcg aatggctgtt gcactggcta tcctctgatc tgtgatgatt ttttcatgat
    30541 agcctgcact tttacgtcgg atcggatgta attccatagg gtggacatac ttggcatttt
    30601 cctttgcata acttaatccc aagatatgat ttggcgaaga aaaatcaagc gtaatatcgg
    30661 gatacagact gcgaaaaacc tcagtcattt tttgcggata actatacgtt tgatcagaca
    30721 gttcttgaaa tgcctcttct atcctatctt gattctcttg gacaaagcgt ccgaaactgc
    30781 tgtaatcaaa cgaagtctct tcttctgttc caaaacacaa actgtcacag tccagtgttt
    30841 gcaagatttt tactgcacct ttagcaaaat agtcagctga ctgaaccgcc cattcgacgg
    30901 gaagctccac tactaaatcc acaccatttt gtaaagcttc attcgcgcga tgccatttat
    30961 cgatgatagc cggttcgcct ctttgcaaaa aattcccgct cattacagca atgacgacct
    31021 ctgctcctgt tatttttcgt gccatttcca catgatagcg atgtccattg tgaaaaggat
    31081 tgtactctac gataatcccg cagcttttca tgcgcatcct ccttcatagt tatcgataaa
    31141 aaagaaatag agacaagtaa aaaaaggcaa aaatcggaaa aaatacccga actatataaa
    31201 ctattctcgc aaacacaata cttctgcgac gaaaagctgc actgcaagag caatgcctat
    31261 atcgttcgga tatataattt atgttgaaga tttattcttt tcttgttaac tcgagcaggc
    31321 aaaaccgcta gtctttgtat gctacaaaga accagcgctt tgatttctct gatgctgctt
    31381 cgtctgtaaa atcagaaaat gcttcgactt tcgaaaagcc gctgttttcc agcattctta
    31441 aataactttc caatggatag gtacgctctt gatgtagttc atcttcacga ataaatcgac
    31501 cagacccttc ttgttcttca acgaaaaagg taagaaaatg ttcgatgctg tgtttctcgc
    31561 ttcctggata actatcccac aaaaaagcaa aattatcccc ttgataatga tagctatatt
    31621 ctggaaaaac ctcatctact tgataggtgg agtgtacgtc aaataaaaat cggccatttt
    31681 cttctaacgc ttgatagact tcatcaaaca cttgctgtac ctcttgtcta tttttcatat
    31741 agcacagcga atcagaaaaa caggtaattg cctgatattg tccgatttct gataaatcga
    31801 gcatattgcc ttccacaaat tggatcgatg cgtcttcttc atatgctcgc tggctggcaa
    31861 tcatcaacat ctcttctgaa aggtctaacc ctgtcacttt atatccatct tttgcaaagg
    31921 caaccgctaa tgctccagta ccgcatgcca gttccaaaat attttttgtg tcttcttgta
    31981 aatgacgttt cgaaaaagct aaccattgct gataaagtgt ttcgtccatc acttcatcgt
    32041 aaatgaaagc aaatgtttca taagccatat gttaatccaa ccattcacta agatcgacta
    32101 gcggagcatc tgaccatagt ttttccagat tatagaaatt tcgttctggc gcatggaaaa
    32161 catgtacgat cacatctcca agatcgatca atacccattt tccgccttct tttccttcaa
    32221 tacgttttac ttcatatttg ttttcttctt ctttatcaat gatttcttct gtaattgcgt
    32281 tgatttgacg ttcgctattt gctgaacaga tcatgaaata atctgccaac aaggaaacat
    32341 ttcgaacgtc taaagcgata atgtcttctg cccgttttga atctgctgct tcaatcgcaa
    32401 tttttaattg ttctttacta tctatgatga tttcctccta atatgagcag cttatttttt
    32461 tgctacccag taattatatg tttcgattgt ttttggataa atctgttgtt cttgcgcaag
    32521 caaatgggcc aatgtatgtt ttgtttcaaa tgctacagct tcgtctagat cagcccatgc
    32581 aatggctcgt gcatcttgta ccccaggaaa atctcgacct ggttcaatat agtctgctac
    32641 ataaatgatt ttgtcaagga gactcatctt agcagcccca gtcgtatgca cccggattgc
    32701 atgaagaatc tctgcatcgg tgattcctaa ttcccgctct acaaacgaag cgccaacaag
    32761 accatgccag attgcattat tataattcaa taactccgga tcaaaaccgt ctcttacgat
    32821 taccattttg aactcctcat ctggtcgttc ttttgcataa tcatgtgtca atgcagcaat
    32881 actagctttt tcaggagaag caccgtattt tttggcaaga gccacggctg tttcttctac
    32941 tccaagcaca tgcttgaagc gttgttcgct cattctcatc tgtatttttt gcatcaggtt
    33001 ttctctagaa taagcagtat attcattact atagtccata ttcatacaac ccttcatttt
    33061 gaatataatc aattacttta tctggaacaa ggtagcggat agaacagcct tctttgatct
    33121 tttgacgtat tttcgtggaa ctgatgtcga tctcaggtac atctacccaa attacaggat
    33181 atggagtatc cgttgtgtat cctggtcgac gtatacccac aaagttgacc atagaagtca
    33241 gctcatcgat tttataccat tttggcaaat attctaccat atccccaccg ataataaagt
    33301 aataatctgt atccggattg ttttgcgtca attccttcat agtatcatag gtgtaacttt
    33361 tcccaccacg agctaattca atcgtttcaa tctgcaaaaa aggattgtct tccaccgcta
    33421 attccaacat gttgagtcga tgttttgcat caatcgtctg tttctcatca acatgaggtg
    33481 gctgataaga aggcatcaaa aatacgcggt caagacctaa attccggcca gcttgttcag
    33541 ccatcactaa atgtgcaagg tgaacgggat tgaatgttcc gcccaagatc cctacttgct
    33601 ttttcttctc taagaattga ggcatttctt caggaaataa ttgtgaacga acaaatgtct
    33661 tagcttgcgt attcatcatg gtcactcctt atattgcttt tacttctttt gatagccttt
    33721 gatacttttc ttttgtggaa ggtttgtata atacaataac acgtccaatg atttggacga
    33781 tttcgcaatc tatttctttt tctaatactt gagctgcttc ttctgcaatc tcatctgtat
    33841 tttgaagtaa cgatactttg atcagttctc ttttttctaa agcttcttca atttgaacga
    33901 tcattgctga attgatccca ccttttccga tttgaaaaat cggctgaaga tgatgcgctt
    33961 tgctacgtaa aaaacgcttt tgttttcctc ttaaactcat aattttcctt cttccttaaa
    34021 tcaatgcttt gcgtttcaat acatctacac cctttggcgc ccagcccgca attactactg
    34081 gcgctgttac agtgatccag cctagaccgg caaaaacgat gtctgttttt tctttcacag
    34141 aaaactcaaa acgaacaagc tccggaaatg cctcgacttc atcaggacga ggaggctgta
    34201 ataatccacc tacatgtttt tgataaaatt cgtctgcttt ttccagtttc gttcgatgaa
    34261 tatttacatc atttgacaca taagcaataa atgaagcacg attgccgctg ataaaatcaa
    34321 atcttgcaag tccgcccaag aaaagtgttt gcccttcatt cagctgataa actttaggtt
    34381 tgatttcttt taacggtgca atgatccgca aatctttttt acctaagtag tgcgccattt
    34441 gatggcgatg gataattccc ggtgtatcaa tcaaaaaatg cccgtcatct aaaggaatct
    34501 cgattttatc caaggtcgtt cctggaaact gcgaagttgt gattacatct tgtactcccg
    34561 ctgtattttt gatgatttga ttgataagcg tcgattttcc gacatttgtt actccgacga
    34621 tatagacatc ccgtccatcg cggtattctt cgattttttc taatagttcc gtcatctcat
    34681 gagatttctt agcactagtt aataatacat ctactggacg aattcctgct tcgtaagcac
    34741 gttccttcat ccattgtgtt aatttagttt ttttcaatga tttaggtaat atatccactt
    34801 tgttcccaac taaaagtact ggattgtcac cgacaaaacg gtgtagtcct gggattagtg
    34861 aaccattgaa gtcaaaaata tccaccacat tgacgatcaa tgcatctttt tgccctaatt
    34921 cattcagtaa gcgcaaaaag tcgtcatccg tcaatgagac atcttgggtc tcattataat
    34981 ggcgtaatct gaaacaacgc tgacaataga cttccccgga agctaaacct ttttccaaag
    35041 ccgtttgcgg cgtgtatcct aattcaccgg gtttgtttgt ttgtataacg gcaccacagc
    35101 cgatacattg taattcttct gtcattcgat tccacctcgc cagcccatat cagggtgttt
    35161 tgctaataga taggccataa ttcttttttc ccaaaaacga ttaaattgtg tcttccaact
    35221 atctgttgcg ataatgggtt ttacaaggat gctacgtatc cctgcacgat tggctccacg
    35281 tatatcagtc ataatctgat cgcctaccat tactatctca tcatctgcta aatccaattg
    35341 tttctttgct atgttgatcc ctcttgctaa aggtttcatt gctcgtgcaa catacaaaag
    35401 atcaaatttt tcaatcgctc gcgcgacacg ttttgaatta ttgtttgaaa caacaacaac
    35461 agggattcct gcatttttca tttctaaaat ccaagtaagc aactcttctg ttccatctgg
    35521 attattccat gcaatcaacg tattgtctaa atcggtcaat actgctttga tgcctagatt
    35581 ctttaattgg gcaggtgtaa tctgatagat ggcttctacc atccatgttg gtttgtaatt
    35641 tgaaaacatg ctgtctcctc atctgcaaaa aatgaaggag cacataaagt actcctcaac
    35701 cccgtattat actgcatatc agcaaaaaaa actacctcta tactcgttcg tctttcagaa
    35761 aaagcatttc tttacaaaat gaccaaaaat aaagattgat cacagaaaaa tttagaaaca
    35821 aaaaacaact aatattggcg gaacctcttg tatcgttttt ccagtaattt atgctgatct
    35881 aatcgaacaa gttccgtcaa tctttcaatc aacgcttttt tcataatgtg tgcgacttta
    35941 tatcgtggca actgctcgcc gttgaacgtt tcaggaataa ctcgatcaac gattcctaac
    36001 tcgcgtagtt ctggcgcagt aattttcatc aactcagctg cttctgcggc gcgactaccg
    36061 tctttccaca aaatcgacgc aaatccttct ggagaaagca cagcataaat cgtttcttcc
    36121 agcatccaga cttcatccgc taaacctaga gcaagggcac cgccacttcc accttcacca
    36181 atgatgatgg cgatgatcgg tacctttaaa tcagacattt cgagcagatt tctggcaata
    36241 gcctctcctt cgccgcgctc ttctgctcct acaccgcaat atgcacctgc tgtattgatc
    36301 aaggtaatca ccggtctatt gaacttttcc gcttgtttca tcagtcgtaa agcttttcga
    36361 tagccttcag gatggggaga accaaaattt ctgcggatat tttcctgcag atcccgtcct
    36421 ttttgaatac cgatcactgt taccggtttg ccatctaatc gagcgattcc accaacaatc
    36481 gcttcgtcat ctgcaaataa acgatcacca tggcattcct cgaaagaatc gaagatctct
    36541 tcaaaaaaat ccaagcttgt ccatcgttct ttagctcttg ctaactgaac gacatcatgt
    36601 gctgtcttat ccacgatcta tccatccttt ctgtgtatgc aattcaagaa gcgtatggat
    36661 tttctgtttc aattccatgc ggggaacaat ctgatcgaca aaaccatgag ataataagaa
    36721 ttcagccttt tggaaatctt ctggaagttc ctgcttgatc gtctgttcga tgacgcgtct
    36781 tccagcaaaa ccgatcaagc tttggggttc tgctagaata atatcgcctt ccattgcaaa
    36841 actggcagtt actcctccgg tcgtcgggtc cgttaaaaca gttagataaa aaagaccttc
    36901 attgctatgc cgtttgacag cagcagagat ttttgccatc tgcattagag aaaagattcc
    36961 ttcttgcatc cgtgcgccac ctgaagctgt gaacaagacg actggaagac tttcctttgt
    37021 tgctcgttcg aataatctgg tgatcttttc tccgacaatc gttcccatac ttcccatgat
    37081 aaaattagga tccatcactc caataatgaa gggaatcccc tgaatggttg ctttaccagt
    37141 gaggactgct tcatgaagtc ctgttttatc ttgcattttt ttaatttttt ccgtatattc
    37201 gggaaatgct agcggatctt tggttacaag atccgtatcc cattcttcaa aacttttttc
    37261 atcaataatc aaagctagac gctgccatgc accgattcga aaagcgtatc cgcaatgagg
    37321 gcatactttt tcttcaccga tgtctttcgt ataaaggata tgtttgcaat ttggacactt
    37381 tgcccacatg ttatcaggaa cagatggcga gttagcaggt ttgctctctc tattaggatt
    37441 gatccgaata tatttctttt tcttaaacag agccatctat gcgcctccta tctccgtttc
    37501 tggtgtccaa ttcggtaaaa attcttcttg taaaaatgct gtgctgtaat cacctgctat
    37561 gactgcagga tgactaatca aatccatctg aaattctgcg ttcgtgatga ttccttctgt
    37621 gataaattca cttaaggctc gctgcatctt cattaatgct tcaaaacgcg tatttccatg
    37681 gacgattatt tttgcaatca ttgaatcata atatggcggg atcgtatatc ccgggtaaac
    37741 tgcactgtct actcgcagtc ccatcccacc tgctggaagc agtaagtttt ggatcttccc
    37801 tggagaagga gcaaaatgga aagcaggatt ttctgcatta atccggcatt cgattgcgtg
    37861 tccttggaat actacttctt cttgacacac attcaaaggc tcaccggctg ctatctccac
    37921 ctgttttttt actaaatcga ttcctgtgac catttctgtt actggatgtt ccacttggat
    37981 tcgagtattc atttccatga aataaaaatc gccttcttca tccatcagaa actcgatcgt
    38041 tccggcattt tcataattga ctgctttagc tgctcgaaca gcagcgtctc ctagtgcttc
    38101 tctttttgtt tgtgagatca ctacagaagg agattcttcc agtacttttt gattgttgcg
    38161 ttgtaaagaa caatctcgct cgcctaaatg aatgacatga ccaaatcgat cacctaagat
    38221 ctgaacttct atatggcgag caggataaat gattttttcc aaatacatat catcatttcc
    38281 aaatgccgct gctgcttctt gctgagctga agaaaaatgc tgtgggagct cttcttttga
    38341 ttgaactttc cgaatgcctt tcccgccacc acctgcagct gctttcagca tcactggata
    38401 accaattctg tctgctattt ccaatgcttc ttctactgta gataatacac cagtacttcc
    38461 tggaatgact gggacatttg cttcttgcat caattgacgc gcattgatct tatttcccat
    38521 tgcatcgatc gttgcacttt taggaccaat aaatgtgata ttgcactctt cacacatgga
    38581 ggcaaatcgg ctattttcag ataaaaaacc aaatcctgga tgaattgctt cggcttttgt
    38641 cacgattgca gcgctcagta cttcctgaac attcagatat gaatcaacgg cttttgccgg
    38701 gccaatgcag attgcttcat ctgctaactg tgtatgaagt gcttcggcat ctgcttctga
    38761 atatatcgct acggtttgga tccctagttc gcggcatgca cgaatgatac gtacagcgat
    38821 ttcaccgcgg ttagctatca atactttaga aaacatattt cacctatcca atcataaagg
    38881 ttaattccgc ttcggctact tttttaccgt ctactttagc gattcctttg cctattccgg
    38941 ctgaagcttt cactttcaat atctcaactt caaggtataa ggtatctccc ggtgtaactt
    39001 tcttacggaa ttttgctttg tccaatccgc cgaaataagc cgtctttccc ttgaattgtt
    39061 caagagaaag taatgcaact gctcctgctt gagccattgc ttcaacaatc aatacccctg
    39121 gcataacagg ttcttctgga aaatgtcctt gaaaaaaggg ctcattgatc gttacatttt
    39181 tcttagcaac gatccgttct ccttcaacca tttcttccac tcgatcaatc aaaagcattg
    39241 gataacgatg tggaatgatt tcttttattt cttgtatgtt cattgttttc cctctttcct
    39301 gctttgctta tttttgctga atcctaaaga gtggctgtcc atattcgaca actgactcgt
    39361 tttctacaag gatttctgtg atcactccgt cggcctcact agttatctca ttcatcagtt
    39421 tcatcgcttc aataatgcag ataacttctc ctttggcaac ttgatcacct acttttttga
    39481 aagctggttt gtcgggcgct ggttgcagat aaacgattcc cacgattggc gaaacaacct
    39541 cgattccatc aaatactgcc gattcttttt ctttcattat ttctggagca gttgttgctt
    39601 gttcaggtat gacattgact ggctccgaaa ctggcaacgt ttcgtttgtt tgaaccatat
    39661 tcatgcctcg acttgtttta tttttattca tatacaattc aaattgacct tcacgcaaat
    39721 cgaattccgt tagcgaggat tgatcaaatt gactgactaa ttctctgatt tcattgatat
    39781 ccaaaattat tcctcccagc gtttcatgca cagaaccgca ttatgtccgc caaaccctaa
    39841 tgaattactc attgcataag taaaacttgc aggtttgctt tcgtttttga caactgtcaa
    39901 gtcaatctca ggatcttgtt tttctacatt gatcgtaggt gggataaatt gatgttctaa
    39961 tgccagcaaa gttgccaagg cttcgatccc gccggctgct cccaataaat gtccagtcat
    40021 cgatttcgtg ctgctgacgt aagtatctct gaaattttca cctaatgcga tttggattgc
    40081 ttttgcttct gcctggtcat tggctggtgt acttgttccg tgagcattga tatatccgac
    40141 ttgttccggc tgtacaccag cttcttccat cgcaagcttc attgctttag atgcaccaga
    40201 accatctgga gtaggagctg tcatatggta agcgtcacag tttgcaccgt atccaacgat
    40261 ttctccatag attttggcac cgcgagcttg tgcatgttct aaagattcaa gaactagaac
    40321 gcctgctcct tcacccatca caaaaccatt ccgattttcg tcaaacggaa tcgaaccacg
    40381 attaggatca gttgattctg agagtgctgt taaagctgca aatccagcaa tccccatctc
    40441 acaaatcgtt gcttctgttc ctccagcaag aatgacatca gaatagccat gtttgatgtt
    40501 acggaatgct tccccaattg aattcgttcc gctagcacaa gctgttacga tagctgtaca
    40561 aatacctttt gcacctacac gcaaagcaat atttccagct gccatgttgg caatcgccat
    40621 tggtacgaac attggagaaa ctcgttttgc acctttttca tgtagacgaa taacttggtt
    40681 ttcgattgtt ggaagaccac cgatcccaga tccgatgatg acgccaaacc ggtcttgatt
    40741 cattttttct ttatctaaac cgctcatctc cattgcttct aaagcagcgt agattccata
    40801 gatcgaaaac atatccattc gtttgctatc ttttttaata aaatatttat cgtaagggaa
    40861 atctttgact tcacccgcta aggtaatccc tgtttctgaa gcatcaaatt tagtgatcgg
    40921 tgcgatgcca ttcgtcccct cttttaagct attcaaaaag ctgtctgcgt catttccaat
    40981 aggtgaagtg actccatagc cagtaattac cactcgattc atttgtttgc tctccttttc
    41041 ttatccgtgc atgaccaatc cgccatcgac attgatgact tgtccggtga tatatggatt
    41101 ttgtgctaag aaaactgctg tttgtgcaat atcttctact tgtccgaaac gctgcatcgg
    41161 aatttgcttt tccgcttgtt ccttgacttt gtctgctaaa acttccgtca tatcagttgt
    41221 gatgaatcct ggcgcaatgg cattacatgt aatgcctcta gttgcagctt ctcgtgccac
    41281 agattttgtt aatcctacta cgccagcttt actagctgca taatttgctt gaccaatatt
    41341 tccaatcaac ccagatacac tagagagatt aatgatggcc ccttctcgct gcttcatcat
    41401 ttttttcaat acgtgctgcg tcatattgaa ggttccaatc aaattgatat ccagacattt
    41461 tttgaaatct tctgcatcca ttcgcatcac aagtttgtca tttgtgattc cggcattgtt
    41521 tactaacaca tggatcgatc caagcttttc ttctgcttct ttgatcattt gtcccgcttt
    41581 ctcataatca gagatgtcac cggaaactcc tacgcatttt acaccgaatg cttcgatttc
    41641 ttctatcttt tcttttggaa tctctccgcg accattcaaa atgatatttg ctccagcttt
    41701 tgcaaaagct aaggccatcg ctttgccgat tcctcttgta ctacctgtga taaatacatt
    41761 ttttcctttt acatccataa cgttcctcct tatagtattg ctattgtttc atcaaatgtc
    41821 tgcttattct caacacgcag aactggtatt gttttatcga tttttttcat aaatccgctt
    41881 aatacttttc cggggccgac ttcgatgact tgttcgatgc cgattgtttt taacttatgg
    41941 atactctcat agaaacgaac aggttgcatg acttgctgtt caagtagtcc cgcgattgtt
    42001 tctttcttca ttatttccgt tgttgtgttg cttatgatag gaaaagaagg ttcagagaat
    42061 tgaatctgac ttaggtcctt cgccagtttt tttgctgccg gttctaaaat agctgtatga
    42121 aaaggcccgc tgacatttag agggatcatt cttttgaacc ctttttcttt taatagtaaa
    42181 acagcttcgt ctactgcttt ttcttcgcca ccaatcacga tctgctgagg tgtattataa
    42241 tttgcaggag atacgatgcc gtacttgcta gcttcatgac agctttcctc gatcgtttca
    42301 atcggcgcat tcatcactgc aaccattttc ccgcttccag ctggggcagc ttctgtcata
    42361 taagcgcctc tttttgctac taacgcaact gcttcagtga aggatagcgc attactagct
    42421 actaatgccg aatattctcc taaactcagt cctaaagctg catctgggat gattccatgc
    42481 tccttcaata agcgataata cgcgatgctg actgttagaa tagctggctg tgtatattgc
    42541 gtctgatcca aacgttcatt ttctgtaaag caaagttcag ccatatcgta gccgagaatc
    42601 tcacttgctt catcaaatgt ctgctttaca acggcttctt catataaatc ttttcccata
    42661 ccttgatatt gtgcaccttg gccactaaat aagaatgctg ttttcatgtt tttctccaat
    42721 atatccagaa tatatgtttg attcttccta ttcaaaaagg ccgagacatt cctatttcag
    42781 gaaatgtccc agcccccaac ctaattttaa tgattatgca gtttgttttt ctacgtaagt
    42841 cactaaatct tgaaccgttt tgattccgtc ttctgtttcg attttcacgt caaattcatc
    42901 ttcaatttca ttgatgattt ggaataaatc caagctgtca gcttctaagt cttcttggat
    42961 gtcagtagtc aatttgattt cttcagtttc ttttcctaat tcttctgcga tgatttcttg
    43021 aattttttcg aataccataa taatatattc ctccgatatt gtttgctttt tatttttata
    43081 atttaacagt ctacaactcc atgagaatac ttccccatgt taaacctccg ccatagcctg
    43141 taaatattac tttctgctgt tttcctaagg tgatctttcc actagaaact gcttcatcca
    43201 ataagatagg gatgcttgca gcagatgtat tcccatattt atccatattg gtcaggaact
    43261 tttcttgcgg catctttact tttcgggcaa ttttctcaat aattctgagg tttgcctgat
    43321 gcaaaagcag ataatcaact ggtttgtctt tcatgacttc ttggatattg tttgcaacgt
    43381 ctcgtacggc aaaatcaaaa atatctctgc cagtcatttg caaataatac gaaccttctg
    43441 aatcttctga atagaacgga tttttatttt gctggtagcc agcggtcaat gagctacttc
    43501 tggtaccgtc agctgctaat ttttctttca gcaatttttt ctgtggattc gcttctaaga
    43561 gaatcccacc tgctccatcg ccaaacaaca cagcagtcgt acgatcagac caatcgatta
    43621 gcttagatag tgtttcacca ccaatcacca gtcccttagt tgagccgcag cggatcattt
    43681 tttcagccat gcttaacgca taaacaaatc ctgagcacgc agcactgata tcaaaagcga
    43741 tagcatgagt tgctcccaat ttcccttgta cttgtgctgc tacagatggt gtcgtgtaat
    43801 cgggcgacat tgttgctact aaaataaaat ccaaatcttt agggtttaga tttttctgtt
    43861 ttatcaattt ttccgccact aaaatgcata aatcagaagt ctcctgattt gttacacatc
    43921 ttcgttcacg aatacccgtc cttgacgaaa tccattcatc agaggtatcc atcatcttgg
    43981 aaagatcatt attagtaata atcttttcag gaaggacgct ggctgttgca gtaatcattc
    44041 caaattgttc cattaaatat cctcacttat agtcttgcaa gaagtcgtgc aagtttttca
    44101 gtgcatccag caaggcatgc tgttcctccg tagccattcc gtctaagatg ttcttgacca
    44161 tttcacgatg aaaatgctga tggacccgaa atagtaactt tccttttttc gttagtccca
    44221 actttacaac gcggcggtca tcttcactgc ggatacgttc gacatagcct ttttttacta
    44281 acttgttaat agcagtggtc aaggtcccaa cagtaattga tagttctttg gctacttctg
    44341 aagttgtttt tttcttgtac atcccgattg cctcgatcgt gtgcatctct gtgattgaca
    44401 gatctttgaa ttgagatttt ttcagctcag actcttcgat tgtcaaaata tcattgaaga
    44461 cactaacaag ataatcattt actgttttta aatctggttc catgttccac cgtccactaa
    44521 ttagtttgat tatcaaatct tttgatgttc aaactatatc ttaacttttt tcaaaatgca
    44581 accttaaaag atcatttttt tactatatga gcttttttta agattttact catttaaaac
    44641 aactgataaa tcagcattta taatttcttt tattagaaaa atcatctatc tcacatattt
    44701 tgattatcaa agtattttct gtgaacagaa ctatagaatt ccctaaaact tgtccattat
    44761 ttcaaaattt gttatagtct ttttattcaa agcgtaaaag gagatcctat gttaaaagaa
    44821 aaaatgaaaa ctctccccat gctgccgggt gtctatctta tgaaagaccg agatggtaag
    44881 gtcatctatg ttggtaaagc aaaacggctc aaaaatagag taagcagcta ttttcatcag
    44941 aataaacagc attcaaaaaa agtattacgt atgattcatc atataacaga ttttgatttc
    45001 gtcgtagtag acacggaatt agatgcttta ttgctcgagt gtcaattgat ccaacattac
    45061 cgtccttttt ataaccgaca aatgaattat ttcagtaatt ataattatgt acatattacc
    45121 aataagggat ttgtattaac agatactcct acggctcgaa catacgggcc ttttcgtctc
    45181 tataaaaaaa tgccgtctat tttgcgtata atggaagaaa cttatcaaat gccttggttg
    45241 tctgaaatta gtttgttagc tttgcgagtc cagcttcctg acctacagga aatgactttt
    45301 gaacagaaaa aaaaggaact ccaagggctg tttcaaggcc gaaataaaaa gctactgact
    45361 tacttgaaaa aaagacaaca acatttcatc tatcagttga atttcgaaaa agccggtatg
    45421 cttcaaaaag atatcgaatt agttacttat tttattagac ggatccagga acaaaagcag
    45481 tttttaagaa caccatcgct caccttcagc atgccattag cagcagatga gagtcagaaa
    45541 aagcactacc tcgtttgtta tggtcaactt gcagaaacaa tgattacctc tggtgacgtt
    45601 tctcctgact tctattatga aaagaaagaa gctcatttat ctttgaaacg tcaattgtca
    45661 aaagaagaaa tcgatcctgt acaaatcttg atcagttacc gcaaaaaatt agaaaaagaa
    45721 cagtttgaaa ttgaactgtt aaacaaaaaa gaagctgaaa agcaactaaa ttagttgctt
    45781 ctcggcttct tttaggcatc ttcaacttca aatgtcaatt atcctaaaat ttattggatt
    45841 aagtcataga tttccatcgc tacgatatcg atattatcaa attcgtattg ctgatgagta
    45901 tctgtttcag ttaattcaaa tgtatcggtc gctttatcat aagttactgt acacttctct
    45961 acgccttctt tttcaaaacg gcgaacttgc agttcattat ctgctgactc gaccatagcc
    46021 tccagtcgtt ttatgattgc gactaattgt gaatgtgtca tcggaggtcc tccttttctt
    46081 atttctgtta tattgtatca aaagcatagc ctacttgcat tgattttctc taaaaaaact
    46141 cgttttttat gatttttttt ctggtatttt tccttcaggc caccaaagtt tgatcaaagc
    46201 ttgggttccg tcattctcaa aacctttatc tgccaactct tcatatagtt tcaatgcttg
    46261 ggtagttgct ggcaatacaa gatccatttt ttctgcttct tctaatgcaa tctttaaatc
    46321 tttgataaaa tgtttgacaa aaaaaccagg tgtgtaatct tcttttaaaa tacgaggaga
    46381 ataattgctt aaagaccagt tagctgcact tccacctgaa agcgtctcaa tcactttctt
    46441 taaatcaagt ccgttttttt gtgcatagac aagcatttcc gtcattcctg tcatcgtacc
    46501 tgcaatcatg atctgattag ccatttttgt atgctgacct ttcccagcag aaccatgcaa
    46561 tgtaaatgtc gtaccaaatt ctttgaataa aggcagtact tgatcataaa cggcttcttc
    46621 tccaccgacc atgatcgtca gtgtaccatt ctttgctcct aagtcaccac cggataccgg
    46681 tgcatctaac gcatctgcgc ctttttcttt tgctgttttt gcaatttttt ctgccaggct
    46741 tggtgtactt gtagtcaagt caactaaaat atgtcctgag atatctgcag aaaaaatccc
    46801 cgactgtcca tagtagattt cttctacatc tttggggtaa cctaccattg taaagagaat
    46861 attactttgt tctgctaccg cttttggtgt atctgcccag atagctcctt ctgttactaa
    46921 aggatcagct tttgcttttg tccgattata gacagctact tcgtgtcctg cttctagtag
    46981 atggcgtgcg acagcacttc ccatgacgcc tgttccgata aaaccaagtt tcattttttc
    47041 gacctcctaa aaatcaaaaa tccttgcttc tatgctagta tacgctagaa acaaggattt
    47101 tttcataaaa aatgtttgaa ttttatcttt taaatgaatt taattttatt ttgattcgtt
    47161 caatcgagtc ttcttcttct tttcttcgca tctcttcttc atgataaaca accatgtctt
    47221 gataaaattc gatcatagct tcgccgaaat gtgtagatga aatatcataa agtttagctt
    47281 ctaaaacttt tggatcttta ggaacttcac tggaaatata atcaataagt gctggtgcaa
    47341 agtcttcgtc ggtttcaaaa gttttcccta atgaaggatg atcgaacaat cggttcaaat
    47401 aagcatttcc ttccacgaca caaggtgttc cggctgccat cgcttctgta taagtaagcc
    47461 cttgtgtttc tgaagtagaa gcactgacaa aataatctgc cgctttataa taaagtgcta
    47521 catcattgtt gtccacttct cctgtgaact gcacaaattc ttctaactgc agttctgaga
    47581 tcaattcctc taactcttct acataaggtc cttttcctac gataactaat ctggcgttag
    47641 gataagcgga gatgacctga ggaaacccat taatcaaggc ttggatattt ttttcataag
    47701 aaatcctgct taaagaaaga atcatcaaat ggttttcctg aagacctagt gactccctta
    47761 atttgctgat atcctgctga gtgatatcag aacgtttgaa tttttcaatg tcgataccag
    47821 taggaatcac gcgaagcggt gctattacac catagctacg taatgtatca ataacacgtt
    47881 cacttggaca aactacacct gtcgtatgat ttgcaaataa tctagacaag tattttacat
    47941 gggattgcct gatcactttt cctttaccga tataatgaag gtagtcttca tacatcgtat
    48001 ggtaagtatg gatcagaggt attttcaact tcttagctac catcttccca agtatccctg
    48061 ctccgaattc tgtatgggta tgaataagat ctagttctag ttctttggca accaaataag
    48121 cataccacat gcctctaaca acaactcttc gatccttgaa agaaataaat ggtacacttg
    48181 gcattcgaat cacatctttt tccaacttat ccgcattagg atcggtcgtt gtaaaaatat
    48241 agacttcatg cccatgtctt tctaattctt gttttaatgt tttgatcgat gtagcaactc
    48301 cgctgacttg cggaaagtag gtatcggtaa aaaagccgat tttcatgttt ttcgcctcca
    48361 aactagtcct tgacctgatt tacttttttt aatttgctag agactttttc attcagtaca
    48421 ctttcgtata catttttaag ttcttcaccg attttattga tacttcgctc ttttgctgtt
    48481 tgataaccgg cttgtgtcgt actcggtagt tcttgattgg taatctgttg gatcagtcgg
    48541 ataaattctt cgtttgtctt ccccatatag cagttcttgc tatcttctaa ccagccatta
    48601 tacactggaa tatctcgaac aagtacgttt tgtttgcttg ctaaagcttc taaaacaacg
    48661 atcccttctg tctcttcata agaagggaaa aagaatagat ctgcacctga atacgcacct
    48721 tctatgatct ctccacgaat gtaaccagga aacaggacat tttcaggatg atcttctttt
    48781 acaattttcc ggatgttccg aggaatcgag tacatgggaa catgaccaaa ccaaataaat
    48841 gtgtattcgg gcatcttctt agcaatttct acgaaatcaa tgattccttt acgttcgaaa
    48901 aacaaaccga cacaaatgat tactttttga tccggagaca gtttgaaata ttctctgaac
    48961 ttttgttctt tcattggatc agggcgatat ttctctaagt cgatcccatt ggaaatagct
    49021 tgaatcggca cacggatact atagctttcc aacaactgtt ttgaataagg tgttggcgtg
    49081 atcagatagt ccgctttttg gtacaatcct accagatatt tttttacgat aggagaaagc
    49141 tggttcgatc cgataaagga atttcggaaa tcttcctctg tagaatgcgc atgatagaca
    49201 actttttttc cttctcttct ggctttattg accatattat gactattgat tccgtatgta
    49261 ttgatgtgca ggatgtcata atcttctttt tcatctagtg tataagagat accgacttcc
    49321 gtcagagcac gtttttgatg atcaagcgca cgcccgattc cagattttgc aagcatcttt
    49381 tcactttcaa aatataataa taccttcacc ttacgtcccc cttcacttat atagtataac
    49441 atagcctaca aactgtcact caaacttaag ccctattttt atctattctt actgacaaaa
    49501 acgttttctt aaaaaagaac aaaaaaactg gcgtagctct tttacaagcc acaccagctt
    49561 ttgatacgtt gtttatttta catattcatg aacaagttca acgacttctt ccatcgtatc
    49621 gcattctttc aatgcacgat cagcaagttc agccattttc gctgtgtcca agcgtttcat
    49681 taaactacgc gttttaagaa tagatgtcgc actcattgag aactcatcta gacccatacc
    49741 tactagcaat ggaacagctg tttgatctcc agccatttct ccacacatac ctgcccattt
    49801 tccttcagcg tgtgctgcat caattacatt tttgatcaaa cgtaaaattg atgggttata
    49861 tggttggtac aagtaagaaa cgcgttcgtt catacggtct gctgccattg tgtattgaat
    49921 caaatcgttc gtacctacag agaagaaatc tacttctttt gcaaacttgt ctgctaagac
    49981 tgctgctgct ggaatctcga tcatgatgcc gacttggatc gtatcagata cttccttgcc
    50041 ttcactgatc aatttttgtt tttcttcttc aaagatcgct tttgctgcgc ggaattcttt
    50101 gagtgtagct accataggga acatgatacg taagttacca tgaacagatg cacgaagcaa
    50161 tgcacgcatt tgtgtacgga acatttcgtc gccttgttca gataaactga tacgcaatgc
    50221 acgatatcct aagaatggat tcatttcatg aggtaattgc agatatggta gttctttatc
    50281 tccaccgatg tccattgtac gaacaactac aggttttcct tccatacctt ctaatacagc
    50341 tttgtaagct tcatattggt catcttctgt tgggaagtct ggagaatcca tatacaggaa
    50401 ttcagtacgg tacagaccaa ctgcttctcc accattatta tggacaccaa ctagatcttt
    50461 tggtgttccg atgtttgcag ctaattcaaa atgcttgccg tcagctgtga cagtttctgc
    50521 attttttaat ttttcccatt ctgctttttg tgctgcgtaa tctgcacctg ctttttcaaa
    50581 ttcagctttt tgttcatctg taggatcgat gattacatcg ccttcgatcc cgttgacagc
    50641 caaaatatcg ccttctttga ctttagcagt aatttctttt gtaccaacga ttgctggaat
    50701 ttctaaagaa cgtgccatga tagcagaatg tgaagtacgt ccaccaatgt ctgttacaaa
    50761 cgcttttaca aaattgcgat ctaattgtgc tgtatcactt ggagtcaagt catgtgcaac
    50821 aacgaccact tcttcgttga tcattgatgg atttggtaaa gtaacgccta ataagtgcgc
    50881 taaaatacgt ttagcaacat cacgaatatc tgcagcacgc tcttgcatat aagcattatc
    50941 ttccattgct tcgaacatac cgatatacat atccgttact tcttttagcg ctgattcagc
    51001 atttacgctg ttgtctttaa tattttgctt gatttgacct accatttctg gatctgaaag
    51061 aaccatcaaa tgggcatcaa atacttgcgc ttctgcttca cctaagcttt gcgctgcttt
    51121 ttcacgaatt tgctgcaatt cttcagtaga tttagctaat gcagcatcca aacgagcttc
    51181 ttcagccgca gtatcttcta ctgttgcctt actgaatgtt aaatccggtt gaactagcag
    51241 gtaagctttt gcaacggcta caccgtcact agcggcaatc ccttttagca tttcaaccat
    51301 tattcagata agccttcttt cttcattgtt tcaacgattg ctgccattgc atcagcttcg
    51361 tcagcacctt ctgcagtaat agtaacatca gaaccttgac ctacacctaa agacataacg
    51421 cccatgattg atttcaagtt tactgattta cctttatact ctaagtttac atcagagtta
    51481 aatttgcttg ctgtttgtac taatagtgta gctggacgag cgtggatccc agtttctgct
    51541 actacgtgaa attctttctt ttccatatta atcggtctcc tttaagtgag tgttgttttt
    51601 atgtgagggt tttctttttt agtaattcag agaatcctaa caaatgccac cctttcatct
    51661 gtaaagatta acattttttt tcgttagata caacagtttt cattcaattt cagataaaag
    51721 tattcaaatt attccggatt ctttttcatc cttttcttca cattttataa caaacgtgtt
    51781 tattttcttt ttcttgtcgc tttctcttct cctgacgttt atcattcttt cctttgaccc
    51841 tctttgtttt catatgaaac gaattacttg cttccctttt tatttttagt ataataagag
    51901 tcaaaggtca ggaatggtca atagagattt caccttttct acctcataaa tctcttaaaa
    51961 aactaggggt tattctttta cctcatgaaa aacgagatgt aaaatatgga tgtacccatt
    52021 tttgtgaaag gacgtgaatg attcatgctt tgtcaaaact gcggcaagaa tgaggcaacg
    52081 attcacttgt atgccactgt caatggtcag cggacacaac tcgattactg tcagagctgt
    52141 tatcaaaaaa tcaaaaatca acaaaatgga ggtctgacta atatggccca aaatgatcca
    52201 tttggatttg gcagtttgga cgatcttttc cgttccatgt ctcgccaaat gcaacagcaa
    52261 ggaaattatg agcaaacacc accaacacaa tttggcggaa acaacaactt caatggtggt
    52321 cagccacctc aaggcaatac agaaggttta ttgggagaat acggaatcaa tatcacagaa
    52381 caagcacgac aaggtgatat cgatcctgtg atcggacgcg atgacgaaat caaacgagtc
    52441 attgaaattt taaatcgccg aaccaagaac aatcctgtct tgattggaga accaggtgtt
    52501 ggtaaaacag cagttgttga aggtttagca caaaaaatcg tagatggtga tgtaccgcaa
    52561 aaattaatgg acaaagaagt cattcgttta gatgtcgtat ctttagtcca aggtactggt
    52621 atacgaggac aatttgaaga acgtatgcaa aaattgattg aagagatccg tcaagcagaa
    52681 aatgtgatcc tattcataga tgaagttcac gaaatcgtcg gtgctggttc tgctggtgat
    52741 ggaaatatgg atgctggtaa tattttaaaa ccagctttag ctcgaggaga attgcaaatg
    52801 gttggtgcta ctaccttaaa tgagtaccgc atcatcgaaa aagacgctgc tttagaacgt
    52861 cgtatgcaac ctgtacgggt agatgaacca actgtcgaag aaacgatcag tattttgaaa
    52921 ggtttgcaaa aacgttatga agactatcat catgtaaaat atactgatga ggccatcgaa
    52981 gcagccgcaa ctttatccaa tcgttacgtc caagatcgct tcttgccgga taaagccatc
    53041 gatttgctag atgaaacagg ttctaagaaa aacttgacga tccaaatcgt tgatcctaaa
    53101 acaatcgaga aaaaactgca agaagcagaa gaacaaaaag ttttagcttc tcgagaagaa
    53161 gatttcgaaa aagcagctta ttatcgcgat cagatcaata aacttcaaaa aatgaaagaa
    53221 cgtcagctca ctgaagagga aacacctgtg attaccgaaa aagatatgga aaaaatcgtt
    53281 gaacaacgga caggtattcc agtgggtgaa ttaaaagaaa aagaacagac acaactgaaa
    53341 aacttagcag atgacttgaa agctcatgtc atcggacaag ataacgctgt agatcgagta
    53401 gcgaaagcga ttcgccgaaa ccgtgttgga ttaaacaaac agaatcgtcc aatcggctcc
    53461 ttcttatttg ttggaccaac tggtgtaggt aaaacagagc ttgcgaaaca acttgcctac
    53521 gaactattcg gttcacaaga ttcaatgatt cgtttcgata tgtctgaata tatggaaaaa
    53581 catagtgtct ctaaattgat tggttctcct ccaggttatg tcggatacga agaagctggt
    53641 caattaacag aaaaagtacg gagaaatcct tacagtcttg tcttgttaga tgaagtagaa
    53701 aaagctcatc cagatgtttt gcatatgttc ttgcaaatct tagatgatgg tcgattgaca
    53761 gatgcacaag gaagaacggt cagctttaaa gatacgatca tcattatgac aagtaatgcc
    53821 ggaactggta aagtagaagc aaacgttggt tttggtgcgg cacgcgaagg tgttactcgt
    53881 tctgtattga accaattaaa caactacttt acaccagaat ttctgaaccg ttttgacggg
    53941 atcatcgaat tcagtgcatt atcaaaagaa aacttgatga caatcgtcac actaatgcta
    54001 gacgatgtca accaaatgct ggcagcacag caacttcaca tcgaagttcc tacgaatgtc
    54061 aaagaaaaat tagttgactt aggctatgat ccatctatgg gtgctcgtcc tcttcgacgc
    54121 acgatccaag aacaaatcga agatggtatc gctgaatttt atcttgatca cccttctatc
    54181 catgagttga aagcaaaact ggataaagat ggaaaaatca tcgttacttc taaaccagaa
    54241 cgtttggcta aagaatcagc cgaagaaacg gctgaataaa tccagtttta tagcgtgaga
    54301 cggtatttct ttgagaaatg ccgtctcatt cttttttcag aaaagtcaaa atactgttca
    54361 ttttataaaa aagaaattat aataagagaa acaagcaatt aaaaatacat aaaagaggtg
    54421 agcgccatga aattggtaaa tgtaacaaac agccattccc gtcttgtatt aaaccagctt
    54481 gaaaacactg atgcccatct agtcaaggtc tacacagccg gaaataccac tattgtctac
    54541 actgaagccc ctgaacataa tgaaattctg ctgatcaatg acaaacgtaa aatccagccg
    54601 aaagaaatcg aagatgctaa aaattatttc ttagataaaa tcaaagacgc cgtttaccac
    54661 gaggatgaaa tcaaagtaat cgaattggca ggccttgttg aaatctcgat tccaaaacat
    54721 gaattaggcg ctacattagc cgtgtaaaca aattttgaac ataataatta aagagcgtgg
    54781 gacaaaagta aagaacactt ttgtctcacg ctctaaacac gtataaacgg cggaagcaga
    54841 agcaactcct tcggaaataa gctaaaattc acgaaaattg cttttcaaat ttttgtgaat
    54901 tccagcttat ttcttggagt taaacgcttc tgtctcagcc tctttttctt tctagctttt
    54961 tgatttttct cttttctttt gtacttttct cttttcattt tcagttctac gcgtgtcttt
    55021 atttttaact ttttcctctt tatggatgat tgatcgtact ttttgtgcaa tttgctcgtt
    55081 tttgtcccag tcttttaaat ctaataatcg acataatcgt aacatctctt cttttttctg
    55141 tttttttctt tcacgtattt gccattctgt ttccatgtgt cacactctcc tttctttaat
    55201 catatgtacg caaaataatt tttatatttt tttgattaga catttctatg attttaat
//
LOCUS       DAXQKX010000014        53437 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.014, whole genome shotgun sequence.
ACCESSION   DAXQKX010000014 DAXQKX010000000
VERSION     DAXQKX010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 53437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53437
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.014"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(2..2686)
                     /locus_tag="ACF3MF_000894"
     CDS             complement(2..2686)
                     /locus_tag="ACF3MF_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
                     /protein_id="HFE3926912.1"
                     /translation="MKIIGKKIANRKINWLLISFLILIAMIIFTSNVAEGSIFNWFDD
                     TKSQTEFLTNPLYQNYLKKYNGNFYSQFGMWIGWSVIKSMFAVVDGIQNMIPEVLDLF
                     SFVESAGLNKVYQSVLSTIVVGLMILSLVIVGYKMIIGKGTVDLKSVGMNVVMSISLI
                     LLMPTLIHSGIEFSKTFYNDSTTITDSDEGVAWSLIEQGVTDLAYINKTDQYSMIDKT
                     NDRNNLTKENFWKTDLTQVLTDNVLDKMEKENPIADNLRYELVENSDNEFVATKFSDN
                     FLSTFVDGIKSGYYRYQANLWGISFGLIALAVAYVFSAFIIITAILELAFKRVLGVLV
                     FATDLETGQRSKQVLSDILQCYLTVGFQGFGLSMFAMFVNYLNAGEGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGTGGMNRSKGGKN
                     SGGNDQAEGEERKPERNFGQSLSQKANKTGKTLGYARERGLSGLASDGATMASERATK
                     PFKSMRDIANDTKNKFKEGLDDGTVSAINKNSKPIVAKNKEDETGKYADSMPTRLSDR
                     KDGAKVENADRIMSSSERMREAMKNNAESNTNHASAIQQKVKQDIEERKNAMHGQAKS
                     AEELINQKRQEAKYTPEIMNREEMLRKRVEGRTGANMDEKEALTKERIQEAKNSNTGL
                     EKLVKENLQNSTSSQDRRSVDVRENLQNTTSSQSGNRIVDVRENVQSSASNQSRTVDV
                     RENLQNTTSSQSGNRTVNVRENVLSSGTSQPRTVDVRENLQNTTSSQSGNRTVDVREN
                     VQSSTSSQGFKTVDVRENVQKDSGEMKEKAQKINIVEDRKSAKKFDSNHETVIIDSEI
                     RENDKGSKSRRRFTYEDNELFRDTLNDPNPLFDNLLKK"
     gene            complement(2655..2891)
                     /locus_tag="ACF3MF_000895"
     CDS             complement(2655..2891)
                     /locus_tag="ACF3MF_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3926913.1"
                     /translation="MIGNRLIDQICCLDQNADTLELIECICFNTIVLDLRAVNDSYVT
                     HIIIDQKIAQKLSESLRNWAEGGNNENYWKKDCQ"
     gene            complement(2911..3780)
                     /locus_tag="ACF3MF_000896"
     CDS             complement(2911..3780)
                     /locus_tag="ACF3MF_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaD"
                     /protein_id="HFE3926914.1"
                     /translation="MAEKRMLSKTFLNNASFMKMSDSAKLLYVYLNTNADDDGIVEAY
                     PYVKMLGTPDDDVKILFTKGFVFFLNEDLLAFLPHWLQNQNIRIDRYKPSIYRFKLLN
                     LKPEFFSKLKPIKLDVILKSGQVEPLRVDLMEKWYPVGIPSINHLEVQSSQDQISSDK
                     SSLVKNSIDKINQVDTIINEEIINEKGIQLIHKLGDRFTKSQREKFVQLIVDMKNSTE
                     REFKIRIDGPHYYEQTNKMIIRLFNTINEKLNLGKELNEMKYVNTVSRNHWKEIALEE
                     QDNRMYIIDALSK"
     gene            complement(3934..4236)
                     /locus_tag="ACF3MF_000897"
     CDS             complement(3934..4236)
                     /locus_tag="ACF3MF_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3926915.1"
                     /translation="MEAIKLMISEEQEEMFLKQFYQIATKAIEKAQENAGMTREYLNQ
                     KEMAEYLNVSENFLKNAVRNEGLPVVELGARKFYSKKAVNEFMFARMKRGESFERK"
     gene            4438..5235
                     /locus_tag="ACF3MF_000898"
     CDS             4438..5235
                     /locus_tag="ACF3MF_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFE3926916.1"
                     /translation="MKPNPSEAGKRIKQLRLSCGFTMEELGRKIDNSPRATISNWERG
                     TNLPNPQKLKLLSTITNSTIDWIKWGTLEEYITSYLIDIGYELYIKDFPEIPHKVFKD
                     IQERYSDTFSLDKDYELLNPIIKNIFTKYYSKDFEIYLNEILANNINPLIEEYANQRH
                     SISKELFFKRANSKLQDKIRNGDFKYGEKERMIDSLKQLLDEMDLAYKDISKYSSVED
                     FFYKITKNQFETEKFISDLSKKYNFPYEKNSIIAKFLTDNHDKFKNN"
     gene            5286..6428
                     /locus_tag="ACF3MF_000899"
     CDS             5286..6428
                     /locus_tag="ACF3MF_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFE3926917.1"
                     /translation="MATFFSYKLQNGEKYWGFETYLGKDPKTGKDIRTKRRRFKSKAE
                     AQTALNRLLVDFKEKQEFKINVTTFQELYELWIDNYRTRVKPSSVAVAQRFCKNHILP
                     AFGELRLDKISVSYCQKQVNEWHKTLKQYGFLRKTTAQIFKFGVAMEVCKDNPMSKTL
                     LPRKIEEEQPLKFYTKDQLQLFLQNTKENNSVKMYTFFRLLAYTGMRKSEALALQWED
                     IDYFNKTITIGKTIAQDEFNQVVLQVPKTKNSSRTIQLDDFTLKQLRIWQQEQMKIMI
                     LYGYNTNSPKQFLFTTNTNKLYYPQVVNDWLDWIYKKTPMEPQITPHGFRHTHCSLLF
                     ESGASIKEVQERLGHKDIKTTMNIYAHVTPQSVKKTGDRFAKFMGE"
     gene            complement(6526..7917)
                     /gene="sufB"
                     /locus_tag="ACF3MF_000900"
     CDS             complement(6526..7917)
                     /gene="sufB"
                     /locus_tag="ACF3MF_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HFE3926918.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(7922..8392)
                     /gene="sufU"
                     /locus_tag="ACF3MF_000901"
     CDS             complement(7922..8392)
                     /gene="sufU"
                     /locus_tag="ACF3MF_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HFE3926919.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(8379..9614)
                     /locus_tag="ACF3MF_000902"
     CDS             complement(8379..9614)
                     /locus_tag="ACF3MF_000902"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HFE3926920.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAH
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     SFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVINPVQELAELVHENGGVIVVDGAQSAPHMTIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQELGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VIAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFKHGTI"
     gene            complement(9611..10897)
                     /gene="sufD"
                     /locus_tag="ACF3MF_000903"
     CDS             complement(9611..10897)
                     /gene="sufD"
                     /locus_tag="ACF3MF_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HFE3926921.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(10910..11683)
                     /gene="sufC"
                     /locus_tag="ACF3MF_000904"
     CDS             complement(10910..11683)
                     /gene="sufC"
                     /locus_tag="ACF3MF_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HFE3926922.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(11880..12728)
                     /locus_tag="ACF3MF_000905"
     CDS             complement(11880..12728)
                     /locus_tag="ACF3MF_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFE3926923.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(12752..13438)
                     /locus_tag="ACF3MF_000906"
     CDS             complement(12752..13438)
                     /locus_tag="ACF3MF_000906"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFE3926924.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(13431..14465)
                     /locus_tag="ACF3MF_000907"
     CDS             complement(13431..14465)
                     /locus_tag="ACF3MF_000907"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFE3926925.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     misc_binding    complement(14528..14784)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(14860..15198)
                     /locus_tag="ACF3MF_000908"
     CDS             complement(14860..15198)
                     /locus_tag="ACF3MF_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HFE3926926.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(15200..15556)
                     /locus_tag="ACF3MF_000909"
     CDS             complement(15200..15556)
                     /locus_tag="ACF3MF_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HFE3926927.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(15562..16749)
                     /locus_tag="ACF3MF_000910"
     CDS             complement(15562..16749)
                     /locus_tag="ACF3MF_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFE3926928.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYFYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVVGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(16940..17785)
                     /locus_tag="ACF3MF_000911"
     CDS             complement(16940..17785)
                     /locus_tag="ACF3MF_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFE3926929.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YPLPQLMKHLIKRFPKVHFEIEIANSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            18019..18984
                     /locus_tag="ACF3MF_000912"
     CDS             18019..18984
                     /locus_tag="ACF3MF_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HFE3926930.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            19484..20527
                     /locus_tag="ACF3MF_000913"
     CDS             19484..20527
                     /locus_tag="ACF3MF_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HFE3926931.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGIKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(20589..21053)
                     /locus_tag="ACF3MF_000914"
     CDS             complement(20589..21053)
                     /locus_tag="ACF3MF_000914"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HFE3926932.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQQILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            21298..22245
                     /locus_tag="ACF3MF_000915"
     CDS             21298..22245
                     /locus_tag="ACF3MF_000915"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFE3926933.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDVDSVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(22456..24528)
                     /locus_tag="ACF3MF_000916"
     CDS             complement(22456..24528)
                     /locus_tag="ACF3MF_000916"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_function: GO:0098847 - sequence-specific single
                     stranded DNA binding [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0051304 - chromosome separation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFE3926934.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEEQKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKEMRINPDF
                     TIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKMLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(24461..24838)
                     /locus_tag="ACF3MF_000917"
     CDS             complement(24461..24838)
                     /locus_tag="ACF3MF_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HFE3926935.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEAEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESGKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(24967..25527)
                     /locus_tag="ACF3MF_000918"
     CDS             complement(24967..25527)
                     /locus_tag="ACF3MF_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFE3926936.1"
                     /translation="MKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDIKAPSLY
                     NHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSNQAVYEL
                     LISVPHTNEAVLLEGIHETNQIILQIFEAFQLTKEEKVHRSRELCSMIHGYLSLRFLG
                     YFTKESTIDPEDSYFWMINDFIATLP"
     gene            25677..26969
                     /locus_tag="ACF3MF_000919"
     CDS             25677..26969
                     /locus_tag="ACF3MF_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HFE3926937.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLAHQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNAAALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLMGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSISSGHSPSHRQ"
     gene            complement(27029..28147)
                     /locus_tag="ACF3MF_000920"
     CDS             complement(27029..28147)
                     /locus_tag="ACF3MF_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HFE3926938.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SEFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILER
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(28161..29582)
                     /gene="arcD"
                     /locus_tag="ACF3MF_000921"
     CDS             complement(28161..29582)
                     /gene="arcD"
                     /locus_tag="ACF3MF_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0043858 - arginine:ornithine antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006527 - arginine catabolic process
                     [Evidence IEA];
                     GO_process: GO:1903826 - L-arginine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HFE3926939.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFAIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVAFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(29828..30949)
                     /gene="mnmA"
                     /locus_tag="ACF3MF_000922"
     CDS             complement(29828..30949)
                     /gene="mnmA"
                     /locus_tag="ACF3MF_000922"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HFE3926940.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNHAEVVFD
                     EPVRAITPGQAVVFYDEMECLGGGLIDHAYQETKVLQYV"
     gene            31353..31952
                     /locus_tag="ACF3MF_000923"
     CDS             31353..31952
                     /locus_tag="ACF3MF_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFE3926941.1"
                     /translation="MNYFTSDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(32102..33426)
                     /gene="efmA"
                     /locus_tag="ACF3MF_000924"
                     /pseudo
     CDS             complement(32102..33426)
                     /gene="efmA"
                     /locus_tag="ACF3MF_000924"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
     gene            complement(33646..33990)
                     /locus_tag="ACF3MF_000925"
     CDS             complement(33646..33990)
                     /locus_tag="ACF3MF_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HFE3926942.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(34127..35272)
                     /locus_tag="ACF3MF_000926"
     CDS             complement(34127..35272)
                     /locus_tag="ACF3MF_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFE3926943.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSCQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLEQLVRAVKK"
     gene            complement(35452..36426)
                     /locus_tag="ACF3MF_000927"
     CDS             complement(35452..36426)
                     /locus_tag="ACF3MF_000927"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFE3926944.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(36506..37381)
                     /locus_tag="ACF3MF_000928"
     CDS             complement(36506..37381)
                     /locus_tag="ACF3MF_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HFE3926945.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     ALIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKEWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            37511..39418
                     /locus_tag="ACF3MF_000929"
     CDS             37511..39418
                     /locus_tag="ACF3MF_000929"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M13-type metalloendopeptidase"
                     /protein_id="HFE3926946.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNEQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIQYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(39958..43260)
                     /locus_tag="ACF3MF_000930"
     CDS             complement(39958..43260)
                     /locus_tag="ACF3MF_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFE3926947.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEVPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESCTYT
                     NAQEGFALMVRDAVPKDHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKDLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIKLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSFLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTVSKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNESPNESPNESPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLI
                     GVVVYVMKQRKK"
     gene            complement(43532..44077)
                     /locus_tag="ACF3MF_000931"
     CDS             complement(43532..44077)
                     /locus_tag="ACF3MF_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFE3926948.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDAVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(44089..44781)
                     /locus_tag="ACF3MF_000932"
     CDS             complement(44089..44781)
                     /locus_tag="ACF3MF_000932"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HFE3926949.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYKPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(44800..45084)
                     /gene="macP"
                     /locus_tag="ACF3MF_000933"
     CDS             complement(44800..45084)
                     /gene="macP"
                     /locus_tag="ACF3MF_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HFE3926950.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(45097..45660)
                     /locus_tag="ACF3MF_000934"
     CDS             complement(45097..45660)
                     /locus_tag="ACF3MF_000934"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFE3926951.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            45887..46537
                     /locus_tag="ACF3MF_000935"
     CDS             45887..46537
                     /locus_tag="ACF3MF_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HFE3926952.1"
                     /translation="MIKRNWPWLLALVLLFLFGFSFVLGLLLIGVVLVLWGLFGSRRK
                     KGKQEEIPALTNELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAKLKAI
                     DLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIKNKQT
                     YEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQKD"
     gene            46661..47857
                     /locus_tag="ACF3MF_000936"
     CDS             46661..47857
                     /locus_tag="ACF3MF_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HFE3926953.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(47958..49334)
                     /locus_tag="ACF3MF_000937"
     CDS             complement(47958..49334)
                     /locus_tag="ACF3MF_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFE3926954.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSFSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIISILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(49371..50237)
                     /locus_tag="ACF3MF_000938"
     CDS             complement(49371..50237)
                     /locus_tag="ACF3MF_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HFE3926955.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(50326..51351)
                     /locus_tag="ACF3MF_000939"
     CDS             complement(50326..51351)
                     /locus_tag="ACF3MF_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFE3926956.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYRLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(51369..52043)
                     /locus_tag="ACF3MF_000940"
     CDS             complement(51369..52043)
                     /locus_tag="ACF3MF_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFE3926957.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKP
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(52224..53120)
                     /locus_tag="ACF3MF_000941"
     CDS             complement(52224..53120)
                     /locus_tag="ACF3MF_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFE3926958.1"
                     /translation="MKKRTGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     RNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYWKFKRQKQLRKNNRS"
     gene            complement(53194..>53437)
                     /locus_tag="ACF3MF_000942"
     CDS             complement(53194..>53437)
                     /locus_tag="ACF3MF_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFE3926959.1"
                     /translation="YVLPTGEAAFTEFIISYGSYNEEIQIVGVENPGPERVPNMKRGS
                     LPATGGNGLLAFLLIGISLMIGAYSWYRKFKMKSEV"
BASE COUNT        15321 a        11268 c         9456 g        17392 t
ORIGIN      
        1 tttatttttt taatagatta tcgaaaagtg gattaggatc attaagtgta tctctgaata
       61 actcattgtc ttcataagtg aatcttcgtc ttgattttga tcccttatca ttttcacgga
      121 tttcactatc aataatcact gtttcatgat ttgaatcaaa ttttttcgct gactttctgt
      181 cttcaacaat attgattttt tgtgcttttt ctttcatttc tccactatct ttttgaacgt
      241 tctcccgaac atctactgtt ttgaatcctt gactacttgt agaactttgt acattttctc
      301 gtacgtctac tgttcgattt ccactttgac tacttgtagt attttgcaag ttttctcgaa
      361 catctactgt tctcggttga cttgtcccac tacttagtac attttctcgt acatttactg
      421 ttcggtttcc actttgacta cttgtagtat tctgcaagtt ttctcgaaca tctaccgttc
      481 tcgattgatt tgacgcacta ctttgtacat tttctcgtac atctactatt cgatttccac
      541 tttgactact tgtagtattc tgtaagtttt ctcgaacatc tactgagcgt ctatcttgac
      601 tacttgtaga attttgtaga ttttctttga ccaatttttc taatccggta tttgaatttt
      661 tagcttcttg aattctttct ttggtcaacg cttctttttc gtccatatta gcccctgtac
      721 gcccttctac acgtttcctc aacatttcct cacgattcat tatttcaggc gtgtattttg
      781 cttcctgtcg cttctgatta attaattctt cagcagactt agcttgaccg tgcatagcat
      841 ttttacgttc ttcaatatct tgtttaactt tttgctgaat tgcacttgca tgattagtat
      901 ttgattcagc attatttttc attgcttcac gcatacgttc agaactagac ataattctat
      961 cagcgttttc aactttagcg ccatcttttc tatccgaaag acgcgttggc atagaatcag
     1021 catattttcc agtttcatct tctttatttt tagctactat aggtttgcta tttttattaa
     1081 tagcggacac ggtaccatca tctaaacctt ctttgaattt attcttagta tcattagcta
     1141 tatcacgcat actcttaaat ggttttgttg ctctttcact agccattgta gctccatccg
     1201 aagctaagcc tgataatcca cgttcacgag catacccaag cgttttcccc gttttattag
     1261 ctttttgaga aagtgattga ccaaagttgc gttcaggttt tcgttcttcc ccttccgctt
     1321 gatcgtttcc accactattt ttcccacctt tagatcggtt cataccacct gttcctttac
     1381 gaaacagcat agctcccata ccaaatgctg aagcaagctg gccatagcct tcttttaaac
     1441 caatatccac gccaaagtaa cgcatgactg ttccactacc ctttattaga acgaacacgg
     1501 cacagatata agcaattgtt tttataaaaa tattcgttga gataccttca ccagcgttta
     1561 gataattaac aaacattgca aacatagaca atccgaatcc ctgaaaaccg acagtcaaat
     1621 aacactgtag aatatctgac aaaacttgtt ttgatcgttg tcctgtttct aagtcagtag
     1681 caaataccaa aactccaagt acgcgtttaa atgctaactc gagtattgct gtaattataa
     1741 tgaaagcact aaaaacatac gctactgcta aagcaatcaa tccaaatgaa attccccaca
     1801 agttcgcttg atagcgataa tatcctgatt tgataccatc aacaaaggtt gacaaaaaat
     1861 tatctgaaaa tttagtagca acaaattcat tatcagaatt ttcaactaat tcataacgca
     1921 gattatcagc tattgggttc tctttttcca ttttgtcgag tacattatct gtcaatactt
     1981 gcgtaagatc cgttttccaa aaattttctt ttgttagatt gttccggtca ttcgttttat
     2041 cgatcatgga atattgatcc gttttattga tataagctaa atcagtaacc ccttgttcaa
     2101 tcagcgacca cgccacgcct tcgtctgaat ctgtaatcgt agttgaatca ttataaaagg
     2161 ttttagaaaa ctctattccg ctgtgaatca aagttggcat taaaagaatc aatgaaattg
     2221 acattacaac attcattcca acagatttta gatcaaccgt tcctttacct ataatcattt
     2281 tataaccaac aatcactagt gaaagtatca ttaagccaac aacaatggta cttaaaactg
     2341 attgatagac tttgttcaat ccagcacttt ccacaaagct aaacaaatct aaaacctcgg
     2401 gaatcatatt ttgaatgcca tcgacaacag cgaacattga ttttataaca gaccagccta
     2461 tccacatacc gaactgactg taaaaatttc cgttatattt tttaagataa ttctgataaa
     2521 gtggattagt taaaaactca gtttggcttt ttgtatcatc aaaccagttg aaaatactgc
     2581 cttctgcaac gttactcgta aaaataatca tagctatgag aataagaaaa ctaatcaaca
     2641 accaatttat ttttctattg gcaatctttt ttccaataat tttcattgtt acctccctca
     2701 gcccagtttc tgaggctctc agagagcttt tgagcaattt tttggtcaat gatgatatga
     2761 gttacataac tatcattcac tgctcttaaa tcgagaacaa tagtgttgaa gcagatacac
     2821 tcgattaatt caagtgtatc tgcgttttgg tcaagacagc agatttgatc tattagacga
     2881 tttccaatca tattaagagt cctttcttgt ttatttactt agagcatcta tgatatacat
     2941 tctgttatct tgttcttcta aagcaatttc tttccagtga tttcgagata ccgtgtttac
     3001 atacttcatt tcattcaatt ctttacccaa gtttaatttc tcgttaatcg tattaaataa
     3061 tctgattatc atcttatttg tttgttcata gtaatgtggc ccatcgattc gaattttgaa
     3121 ctctctttct gttgaatttt tcatatctac tattaattga acgaattttt ctctttgact
     3181 tttagtaaat ctgtcaccta gtttatgaat cagctgtatt cctttctcgt taattatctc
     3241 ttcattgata atagtatcaa cttgattaat cttatctata ctattcttaa ctaaactaga
     3301 tttatctgaa ctaatctgat cttgacttga ctgaacctcc aaatggttga tgctaggtat
     3361 accaactgga taccattttt ccattaaatc gactcttagc ggttctactt ggccagattt
     3421 caaaatcaca tcaagtttta ttggctttaa ttttgagaaa aattctggtt ttaagttcaa
     3481 taacttgaag cgataaatag atggtttata cctatctatt cgtatatttt ggttttgtaa
     3541 ccaatgcggt aggaatgcta acaaatcttc atttaaaaaa aatacaaaac cttttgtaaa
     3601 aagtatcttt acatcatcgt caggagtccc gagcattttc acgtatggat atgcttcaac
     3661 aattccgtca tcgtctgcat ttgtgttcag atatacatat aataattttg ctgaatctga
     3721 catcttcata aaacttgcat tatttaaaaa tgttttggac agcattcgtt tttctgccat
     3781 ggatttcaca cttctttcta tttgaatggt aaaataaatt caaataaagt tttatcagaa
     3841 ctttattgtt gggtgtttcc cttcgtctac aaactatcgg gagcactctt ttatatattt
     3901 ttttcaattc ttttcaagtc taaatttgtt atttcatttt ctctcaaaac tttcacctct
     3961 tttcattcga gcaaacataa actcattaac tgcctttttc gaataaaatt ttcttgcccc
     4021 taattcaaca acgggcaatc cctcatttct caccgcattt tttaaaaagt tttcgctcac
     4081 atttaagtat tctgccattt ctttttgatt tagatattct ctagtcatac ccgcattttc
     4141 ttgagccttc tcaatcgctt ttgtagcaat ttgataaaac tgctttagaa acatttcctc
     4201 ctgttcttct gaaatcatta attttattgc ttccacaaaa acctctcctt tttaattaat
     4261 tattctataa ctcctctacc tttataagta caaataaata caaattgcgt aaaaaaatgt
     4321 atttatttgt atttataaga ataaagtatc atactccaga taaaaagtaa atacttttaa
     4381 atacttttat ttgataaata tgatatacta tctttaaaaa taaaaaggag aaaaaagatg
     4441 aagccaaatc cttcagaagc aggaaaacga atcaaacaat tacgcctttc atgtggtttt
     4501 actatggaag aacttggaag gaaaatagat aattcaccac gtgcgaccat atccaactgg
     4561 gaacgtggga ccaatttacc aaatccacaa aagctgaaat tattatcaac tatcactaat
     4621 tcaacaattg actggattaa atggggaact ttagaagaat atataacttc ataccttatc
     4681 gatatagggt atgagctata tattaaggac tttccagaaa tacctcacaa agtctttaaa
     4741 gacattcaag aaagatatag tgatacgttt tcgctagata aagactatga gttattgaat
     4801 cctataataa aaaatatatt tacaaaatat tactcaaaag attttgaaat ttatctaaat
     4861 gagatacttg ctaataatat caatcctctg attgaagagt acgctaacca aagacactct
     4921 atctctaaag agctattttt caaaagagcc aacagtaaac ttcaagacaa gataagaaat
     4981 ggtgatttca aatacggtga aaaagaaaga atgattgatt ctttaaaaca gctattagac
     5041 gaaatggact tagcctataa agatatttca aagtattcat ctgtcgagga tttcttttat
     5101 aaaattacta aaaaccaatt tgaaacagaa aaatttattt cagatcttag taaaaaatac
     5161 aatttcccat atgagaaaaa tagtataatc gcaaaatttt taactgataa tcacgataaa
     5221 tttaaaaata attgattctt caaataactt ctctacctgc aataatgaag taaggagaga
     5281 atcaaatggc aacatttttt agttataaat tacaaaatgg cgaaaaatat tggggatttg
     5341 aaacttattt agggaaagat cccaagactg gaaaagatat acgtacaaag cgtagaagat
     5401 tcaaatcaaa agctgaggcg caaacagcac ttaatagact acttgtagac tttaaagaaa
     5461 aacaagagtt taaaatcaat gttacaactt ttcaagagtt gtatgaatta tggattgata
     5521 actacagaac aagagtaaaa ccgtcttctg ttgccgttgc tcaacgtttt tgcaaaaacc
     5581 atatattacc tgcttttggg gaattacgat tggataaaat aagtgttagc tattgccaaa
     5641 aacaggtgaa tgaatggcac aaaacattaa aacaatatgg tttcttgaga aaaacaactg
     5701 ctcaaatttt taaatttgga gtagcaatgg aagtctgtaa ggataatcct atgtctaaaa
     5761 cattgcttcc aagaaaaatt gaagaagaac aacccttgaa gttttacacg aaagatcaat
     5821 tacaactgtt tttacagaat actaaagaaa ataattcagt taaaatgtac acttttttcc
     5881 gtttattagc ttatacagga atgcgtaaaa gcgaggcatt ggcgcttcaa tgggaagata
     5941 tagactattt caacaaaaca ataacaattg gtaaaactat cgctcaagac gagtttaatc
     6001 aagtagtttt acaagtacct aaaactaaaa attcatcaag aacgattcag cttgatgatt
     6061 ttacacttaa acaactgcgt atttggcaac aagaacaaat gaaaataatg atcttatatg
     6121 gctataacac gaattcacca aaacagtttc ttttcactac aaacacaaac aagttgtact
     6181 acccccaagt agtaaacgat tggttagact ggatttacaa aaagacaccg atggagcctc
     6241 aaattactcc acatggattt aggcataccc actgtagctt attgtttgaa agtggtgcgt
     6301 cgataaaaga agtacaggaa cgattaggtc ataaagatat taaaactacc atgaatatct
     6361 atgctcatgt cacaccacaa tctgttaaga aaactggtga ccgatttgca aaatttatgg
     6421 gcgaataatt ccaaacgtag ccaaaaacgt agccaaccat taaaatacaa ataaaaaaac
     6481 gctcgaaacg ctttaatatc aacgtttcga gcaatgaaat agttgttaac ccacagaccc
     6541 ttccatctca taactgatca atcggttgag ttcgactgca tattccattg gaagttcttt
     6601 ggtgaatggt tcaacaaagc ccatgacgat catttcagtt gcttcagatt cggtcaggcc
     6661 tcggctcatc agatagtaga gttgttcttc tgagattttt gagactttgg cttcgtgttc
     6721 taaagagact tggctgttgt ggatctcatt gaatgggatc gtatcggatt tcgaccattc
     6781 gtccatgatg atcgtgtcac attcgatatg agagatcgaa cccgcactgt ttttggcaaa
     6841 ggttacttgt cctcgatagt ttacttctcc gccgtctttt gaaattgatt tagagacgat
     6901 agagctagat gtatttggtg cattatggat catttttgca cccgtatctt ggatttggtt
     6961 tgctcctgca aaggcgatgg agagcatggt gcctcgtgca ccttttccat ctaagtaaac
     7021 acttgggtat ttcatcgttg tttttgcacc taagtttccg tcgatccatt caacggttgc
     7081 gccttcgtat gcttttgctc gtttggttac taagttgtac acattgtctg accagttttg
     7141 gatcgtggtg taacggcaat acgcatcttt tcttgtaaag atttctacga tggcagcatg
     7201 cagactatta cttgaataag taggtgccgt acaaccttcg acatagtgga tgcttgctcc
     7261 ttcgtcaaca atgatcagcg tacgttcgaa ttgccccgtg ttttccgcat tgatccggaa
     7321 gtacgtttgt aatggaacat cgactttgac gccttttggc acgtaaataa aggtgccacc
     7381 tgaccatacg gctgaattca gcgctgctaa tttgttgtcg gttggcggta caagttttga
     7441 aaagtactct ttgaataatt cagggtattc tttcaaagca gagtcagtgt cagtaaagac
     7501 gattcctaac ttttcgaatt catctttcat attatggtac acgacttctg attcatattg
     7561 tgcggaagca ccggctagat aagctcgttc agcttctggt ataccaatct tttcaaatgt
     7621 atctttgatt ttttctggta cgtcttccca gtcacgagcg ggtttgtcac ttggtttttg
     7681 gtaatatttg atggcatcga aatcgatgtc tgaaaggtcg ggcccccatg tttgcattgg
     7741 cattttattg aatgtttcta gagatttcag acggaattca agcatccatt ctggttcgcc
     7801 tttgattctt gacatctcac ggatcacttc ttctgtcaag ccttctcctg tactgaaaac
     7861 cggttcgaca tcatcgtgaa acccgaattt atattcttct aattctggta cgcccatgtt
     7921 ctcactcctc ttccttgtgg taatgatgga aagctgcggt accatcgttt tccattgctt
     7981 ttcctagtgc tttccaggca agtgtcgcac atttgatccg agcgggaaat ttagctacac
     8041 caccaagcat agcagcatcg cctaattggt cgggatcttt gacttctttt ccttggacaa
     8101 gctgtagaaa gtctacagtt aaatgttctg cttcttctat tgattttcca atgacggcat
     8161 ctgtcatcat cgaggcactt gctgtactga tggaacagcc gctgccgtca aaggcgatat
     8221 ttttgatgat tccatctttt acatcaactt gcaattcgat cacatctcca catgtggggt
     8281 tgttcaattc gatcttgctt gtcgagtcag tcaagcttcc acgatgatgt ggatgggaag
     8341 aatgatccaa gatcacttga cggtataaat tgtctaattt agatagtccc atgtttgaaa
     8401 aactcctttg ttgccatgat tgcttcaact aaacggtcgg cgtcttgcgt tgtgttgtag
     8461 aaataaaagc tggcgcgagc agtcgctgat acttcaaggt acttcaatag cggttgcgca
     8521 caatgatgac ctgctctaac ggctacccct tccatgtcta aagctgtcgc gacatcatgg
     8581 ggatgtaacc catccaaatt gaacgcaatg actcctgtcc gaaaattcgg gtcttgcgga
     8641 ccataaacag tcaatccatc gattgcttgt aattttggca acacataagc ggctagttct
     8701 tcttcatatc gatggatatt gtccatgccg agttcttgca aataatcgat tgcatgacct
     8761 aatgcgatag cgccagcgat atttggtgtc cctgcttcga atttccaagg tagttctttc
     8821 catgtactgt cgtataattc gacaaaatcg atcatttcgc caccaaattc aacaggttcc
     8881 atttcttcta accattttcg tttaccatat aaaacaccga tacctgttgg tccgcacatt
     8941 ttgtgtccgc tgaaagcaaa gaaatcacag tctagtgctt gaacatcaat ggtcatgtgc
     9001 ggggcagatt gagcaccatc tactacgatg accccgccgt tttcatggac aagttcagct
     9061 aattcttgaa caggattgat gacacctaag acattggata catgagcaat ggagacgatt
     9121 ttggttttgt ccgtaatctt tttcgctgca tcctccatat ccaggaagcc ttcttctgtt
     9181 agttcgatat atttcaagac agcacctgtt cgttttgcca actgctgcca cgggataaca
     9241 ttagaatgat gttccatgta agagagcact atctcgtctc ctgctttgat atagcggtcg
     9301 ccgaagcttc tggctaccca attcaagctt gtcgtcgtac cacgagtaaa cagcacttct
     9361 gctgtttctt ttgcatggat gaacgcccgt actttttctc ttgcttgttc ataatcatgg
     9421 gtcgcgcgtt ctgctaacgt atggacaccg cgatgaacat tggcgttatc gtgttcgtaa
     9481 tagtgcgcta atgcctggag tacttgtttt ggcttttggg tcgtcgctgc attatccaga
     9541 taaactaaag gttcatcatt gacgtcttga aataagatag gaaaatcatt gcgtagcttt
     9601 ttagcatcga tcatccattc aacttccctt cgattacttc gactaattct ttccgaactt
     9661 gttctacagg gattgctgtt aagacagaac cgaggaatcc tcgaatcact aagcgctctg
     9721 cttcttcttt atgcaatcct cgactcatca gatagtacat ttcttctgga tcaactcgtc
     9781 ctacactggc agcatgtcca gcagttactt cgttttcatc gatcaaaaga ataggattcg
     9841 catcaccacg tgctttatca gaaagcatca agacacgact ttcttgttgg gcatctgcac
     9901 cttttgcccc tttcaagatg tggccgatac cattaaaggt caatgttcct ttttctcgga
     9961 tcactccgtg ttgcaaaata tgcccgatcg tatgaggggc tttattggtt actcgcgtat
    10021 cgattccttg gatttgtctg cccgagctga ttgccacgat tttgacttct gcgtgtgcac
    10081 cttctcctgc taaatctgag tcaaagtcag cgatcacatg accgtcattc atgacaccaa
    10141 ttgcccagtc gacagaagca tctcgtaaaa tgtgcccacg gcgattcata taagaagtaa
    10201 tattttctcc taattgatct acggctgaat atttgatttt tgaaccagct ttagcgatga
    10261 cttccacgat gatattacct gatgattttg ctacttgttc tttggttgtc tggaaacgtt
    10321 ccagataaga aaattcacta tgttcatctg ccacgatcaa cacatgcttg aagaagtgct
    10381 catcggatgc gccatcttga atgaataagg actcgagtgg ttcatcgatc acgacatttt
    10441 taggcacata caggaaaata ccgctgttca taaaagctac atggagtgca gtcaattggt
    10501 cttcgttcat gtttactgct tttttcatat aatattcttg gactagttct ggatattcga
    10561 tcattgcagt gaacaagtcg gtaaaaatga ctcctttttc tgctaattcc acaggcagtt
    10621 gttcaaaaat cgtccatgaa ccttgttgga caagcacagg attgtctttc attgcatcaa
    10681 atgccggaat cgtgcctgtt tcactgatgg tttgtgtttc tttcacatca aataacgacc
    10741 agcgatggaa tttcacccga tcgatatgcg gcaatggcag ttcatctgct ttcgctagtg
    10801 cgtcttgacg gaaggttctc atccaatcag gttcgccttt acttaaagaa aaatcattta
    10861 ccgcgtcaag ataatcgagc cagttttttt ctttcattct tgctccccct tacgcttctt
    10921 cttctttata gtcgattcct aattctttac tgataccagc gtagccttct gcttccagac
    10981 gtttagctag gtcagcattc cctgtcatga ctactcggcc ttccatcatg atgtgaacga
    11041 catcaggtgt gatatagttc aataatcgtt gatagtgggt gatgatcaat gcaccgaaat
    11101 tgtctccgcg catttcattt actcctttag caacgacttt caaagcatcg atatccagac
    11161 ctgaatcgat ttcgtctaaa attgcaaatg ttggttctaa catcaacaat tgcaggatct
    11221 cattccgttt cttttctccg ccagaaaaac cttcgttcag ataacgttca gccatttctt
    11281 ctggcatatt tagtaaagcc attttttcat ctaacttttt caaaaatgcc ataacagaaa
    11341 ttttgtcgtt ttcatcacgt ttcgcattga tcgctgcacg catgaattcc gcattcgtga
    11401 tacctggtat ctcacttgga tattgcatag ctaaaaataa gccaagtcgc gcacgttcat
    11461 ctacttccaa gtctaaaaca tttttcccgt caaacaaaat ttcgccttct gttacttcat
    11521 agtttggatt gcccatgata gcggcagata aggtagattt tcctgtgccg ttaggtccca
    11581 tgatggcatg gatttctccg gttttcattg ttaggtttac gcctttaagg atttcttttt
    11641 cctcgatcga cacatgtaga ttttttattt ctaagacaga catgcattat acccccaaat
    11701 tctctttcgt tctcactcat tttagactaa ttgagaatga agcgcaatga ccttccttac
    11761 taaaatcaaa tatcttttat ttattattaa acaattttga tttctaaatt agaataggta
    11821 taaaaaagat gagaaataag ccattacaga cttatttctc atcttttttg ttccatacct
    11881 tattttgcat cagcctttac tggtttaaca gagccgcccc atttgtctgt gatccattct
    11941 tggacttctt tgcggtgaag cacttcaatc agttttttga ttttgtcact gtcttcatca
    12001 cctttacgag tcgcaataat attcacgtaa ggagagttgt ccttttcaag caatacggca
    12061 tcttctaatg gattcaaccc tgcgccgtaa gcgaagtttg cgttgattgc aactaggtca
    12121 ccttcatcat tttggtacgt agaagctaaa agtgatgggt cgatcgtatg gttgaacttc
    12181 aagttcttag ggttttcttc aatatcatcg aatgttgctg tttccagatc tactccatct
    12241 ttgactttga ctaagccagc atcttgtaga attgtgatga tgcgtcccca gtctgattca
    12301 gaatttgaag taatgattgt tgcaccatct tttaattcgg aaacatcttt gactttttta
    12361 gagtacaagc ccattggttc gatgtggaca gcaccggcat tgacaaagtc atatcctttt
    12421 tctttgattt ctttgttcaa ataaggaata tgctggaagt aattggcatc aatgtcgcct
    12481 tcttccaaag attggttcgg taatacatag tcatcgaatt tgacgatttc aagatcgatt
    12541 ccttcatctt tcaataatgg tttcacatgt tccaaaatct ctgcgtgcgg tgtcggtgaa
    12601 gcgccgactt tcaatgtcgt gtcgtctgct ttatttgctg aatctttgct gtcgctgttg
    12661 ttaccgcatg ctgctaatcc tacagtcagc aaaagcgctg ctgcaaatcc aaaaattttc
    12721 tttttcatat cctacatccc cctatatcct attatctttt gtctgttttc ttagttaaga
    12781 aatcaccgat tccttgaacg ataaatacga ttagtaaaat aattaaagtc gcaacgaatg
    12841 tcactgtcag attaccacgc tggtagcctt cctgccaagc aagacctcca agtccacctg
    12901 cgccgatcgc gccggccatc gcagtaaatc cgatcatcga gatcgttgta actgttaatc
    12961 cagaaatcaa tgcgggaata ctttcaggta tcaagacctt ccagatgatt tcccagtaac
    13021 ttgctcccat tgcatctgct gcttccagta caccagggct gacttcacga aaagcaatct
    13081 ctactagacg ggcataaaat ggtgctgcgg ataaaacaag agctggaatg gctgcttgcg
    13141 cacctagcat agtgcctacg attgctttag taaatggaat gatcaaaacc atcaggatca
    13201 taaatggcgt tgaccggaaa atattactga tgatcgatac gattccataa atgattcgag
    13261 catacggttt gtttttgcgt ccaatagagt aaaggatcaa tcccaaaact aatccgatga
    13321 tcgtcactaa gaccattgag attaatgtca tatatagtgt atcaaggata gcctgattca
    13381 tcgtttccgg gttgatttgt ttaaaatcta gatatgtttc tgaaaagctt ttatccacga
    13441 tggatcacct caattcctac tccttgttct ttgatgaaca cttctgcttg atctaattct
    13501 ttggtttcac cagtcatcaa gacagtcaat gaaccaaagg aaccttcttt cacttgtttg
    13561 atctttccat acacaacgtt gacatcgatg ttatagcgtc gaatcgcttg ggaaatgact
    13621 ggctcgttgg catttctttc gctaaaggtc aaagttgcca aacggccgct tggattttct
    13681 ttgatgagtt cagctaatag ttctgtcgaa tcagcttctg gttcgatgtc ttgttgtaca
    13741 aagcgtttgg ttacttcttt tttcggttgt ctgaagacag tcaatacgtc tccttcttct
    13801 acgactttcc ccaactccat cacagcgact ttgttgcaga ttttgcggat cacattcatt
    13861 tcatgtgtga tcaagacgat ggtcaaattc aatttcttat tgatcgctaa caataagtct
    13921 aatacttctt ctgttgtttg cgggtccaat gcgctagtag cctcatcaca aagcaggatc
    13981 tcaggatcat ttgccaatgc tcgtgcgata ccgacgcgtt gtttctgccc gccggaaagt
    14041 tgtgaaggat atgcttgtcc gcgtccttct aacccgacta aacgcaacag ttcttctgcc
    14101 cgttctttac gtttgctctt tggtacgcca gctaattcca gcggcagctg gatattttca
    14161 agtacagttc ttgaccataa caggttgaaa tgctggaaga tcataccgat tttctttcgg
    14221 aatgtacgta attctttgtt ttttaatttt gtaatatctt gatcgtttac gatcacttcg
    14281 ccgctcgtgg gaagctcaag tccattcagg agacggacta atgtactttt tcctgcgcca
    14341 gaatagccga cgattccata aatatcccct ttttcaacgt ttagtgaaac gtcattgacg
    14401 gcttggatgt ttccgttttt cccattgaat gtctttttga cattcgttag ttggattaat
    14461 gacatgccat tcacatcttt ctcttatgat ttttcaaaca aaaaagcctt cgccctcttg
    14521 ccttaagcaa aaggacgaaa gcttgaactt ccgtgttacc accttgattt accgttactt
    14581 cgcaataaca gcctcttcca gtacttggac ttagcttctt tccgtatact gtcgcgctgt
    14641 aacgggcact cccgtagtaa gtttgcttac gctcgcttac tctgctctaa gaccatcttc
    14701 catctcattt tcgttaccca ttttcagcaa acagggctct cttcaaacgt ccgtgacatg
    14761 tactcttctt ttcaaagctt tctcgtttca tataggattg cttatgatta tagcaactgg
    14821 aagaatcagt gtcaactttt ttcaagtgat tttctgattt tataattcgt caaattcttt
    14881 tggatcaaca tctttgaaac ttaagatcca cgcattcatt tcatctgaat cattcaagat
    14941 attgatatct tcaccgattt tatcattaac agaagaaact gtacccgtta gcgggctggc
    15001 aaattcattg accgcttttt ccgcttcaac ttcgatcaga ggttcatctt tttttagcga
    15061 ttgtcctgct tttggcagat tggcaaacgt gatgtctcca agttcttctt gcgcttcatt
    15121 tgtcaaacca acacagtatt cttttccatt aaataagatc caaaggttgt cctttttctt
    15181 caaatgcttg cctgccattt tatatcagtt ctccttcata aattttttca ttgaatccaa
    15241 ttgcaacaag ctggtcctct cgtaagatca gtggccgctt gatcagcata ccatctgtcg
    15301 ataagacttg gctcgctttt gaagccgtaa actcgcctac ttgatctttc agtccaagtt
    15361 cccgatattt catcccgctt gtgttgaaca ggcgacggat tggtacttga ctcgtttcta
    15421 gccaagtctc aatcgttgag gccttcggta cttctttgat catatcaaca gtttgataac
    15481 taacgccatg ctggtctaac cacgctttgg cttttttgca tgttgaacat ttcgggtacc
    15541 agtaaaaggt gtacaatttt cttacctcct tgaagatctt gcaggtgctt cattttggta
    15601 tctcatcgat aatatcaacc cgataccgat catgttccct aaaatcgaag atcctccctg
    15661 actaatgaaa ggcaatggga tccctgttaa aggaagtaat ccgatatttg ctccaatatt
    15721 ctcaaagaca tggaacagca gcatcatgat caaaccgctt gcgatatagg cgtaaaattc
    15781 attattcgta tcgaaacaca cccgaatcat acgatagatt aaaataaaat acaagaaaat
    15841 gacaaatgca ccaccgataa agccgaagtt ttcaccgaca acggtaaaaa tcatatcgga
    15901 ctcacgaaca ggcacataaa tattgcttac gttgaatcct ttaccaaaca agccaccggt
    15961 accaattgcc aaaagtcctt gggccggctg ataactcatt cctgacgtat catggaaagg
    16021 gtccagccat gaatcaatac gtgcaaactg ataagatttg aagccaactt tgtaaagcaa
    16081 gtctcttccg ccttcagtcg taaccaagaa gatcgttcct gctccaacga ctactgccaa
    16141 gattactaca ggtgcgatga tgcgccaaga gattccagac atcaagaaaa tcccgccaaa
    16201 gatcgcaaga aagacaagca tcgttccaaa gtcatcttgg gccatgatca atgctaaaac
    16261 cggtattgtc acgatcaaga gcttcccaat cagccaaaag tccgatttca tcgtccgttc
    16321 ttttacttgc gtattatgtt tagttacgat cagtgccatc atcaagatgt acgcaatctt
    16381 catcaactct gctggctgga aagtaaacgc accgaatcga aaccagtttt tagaccctgt
    16441 tgaagcagct aaattctgat catagaattt gagcaagagt cccattacca ctaaccccaa
    16501 accataaaag taaggagtca gtttccagat ccatttggaa ttcaaatgca tgatgacaac
    16561 gattgctgcc gctccaacta aataccagac aacttgcatc cctacgcctt tcaagactgc
    16621 tggattgttc ggatcatggc taagtgctac atataatgag agcagaccaa tcaaacataa
    16681 cagaaagact ggtaaaatca cgccataatc aatacgatta tcgttcgaag cttttaattt
    16741 tttttccatg tttcatccct tttcttaaaa accatactgc tgattattat agcggtccag
    16801 ttagataatg gaaagtcttt ccatagacat ttgggaaaaa ttaactttcc gtttgtgcag
    16861 ttgcttgagc aaatgcagta caaaagccta ctgcttatct ttagtgtatc atagaacttt
    16921 ttttgataca tgcaattatc taccaactga gattctcctc gctgtgagaa gtttctgtgc
    16981 tttcattgta tcgaaggatc tcttcggcaa tctctagcag ctgatcagaa accagattgg
    17041 ttcgttggat gaaataaaaa taacgatgga aattcaacgg agtcattggc acattttctg
    17101 gaacagagcg cttagacaaa atcgagcgac cgattccttc cttcagcaac gcaacaatta
    17161 catcgttact tttcacgatc atcttcttat cttggatatt catctcttca aaataacgct
    17221 gcgtgtaatg aaaaacacca gagtttgctt ctcttacaag ccacaatttg ctttttgggt
    17281 ccccagcgat gactagctgg tcttccatca aagagtatct ttgtacgccg gaagtctcta
    17341 atggcttttc gataaaacca aaatcggatt catgtttcgc tacttgttct aatgattcat
    17401 gagaattcgc gatttcgatc tcaaaatgca ctttaggaaa ccttttgatc agatgtttca
    17461 tcaactgagg caaaggatag acagcaaagg tgtgggaagc aacgattcga catacttctt
    17521 cttcattttg ttcattgagc aatttttgct gagtttcttc ccattcttct aacaaaacca
    17581 gtgtccgttc atataataag tcggcttgct tagttggaag catctctttt cttccgttac
    17641 gttgaaaaag atcgatattc aattcccgct ccaactgttt gatttgattc gagactgctg
    17701 gttgagataa aaacagtact tctgctgctc tggaaaaatt tcttgtttca tatactgctc
    17761 gaaaagtcgt taataactta aacatggcac cacttccata actttttatg ataattacta
    17821 taaaaactat ttgatttaaa tatacaaaaa accatctata atagaaatgt acaacaaaac
    17881 agttgctgat ccaactagta acttagatga agacaatcag ctgtctgctt gctcgtaatc
    17941 atacattcct attcatttta caatgtattc gttcatcttg gtactaaaat ctattaaata
    18001 aaaaggagaa tattatatat gaagaacttt ttgaaaatta ttccgatccc gatctgcggg
    18061 ttgatccttg ggttagcttc ccttggaaat ctgtttaaag actatcacca tgttgcttta
    18121 ggcaatctaa ctggcggtat ctctatgatt cttatgatat tcatttttgt taaattgttt
    18181 atcttattcg aacacacgaa acaaacgttg catgatccaa tcatcgcctc cgtttcacca
    18241 acttttacga tgtcactcat ggttatttgt acttattttg tttcatatga aagtattgca
    18301 ccaattgtca aattcatttg gctgtgcgct gttatcttcc aagtgatcct tgtcttttat
    18361 ttcaattatc accatgttat caaagctgat ctttcaattg aagcaattta tccaagctgg
    18421 tttatcattt atgttggatt tggggtcatc actgtaactg ccgggaactt cttcccgctt
    18481 attggaaaaa ttttcttttg gatttcattg atctgctatg cgttcttatt gccgatcatc
    18541 atcaaacgtg tctttttcgt aagaaatatg gctcatccga cacgtccgct gattacgatc
    18601 gttgcagcac ctggttctct ttgcctaaca ggttatctta aaaactttgc tgaacctaat
    18661 ttttatcttg tcgtagcatt gttcgcttta tctcaagtat tgtatttcgt tgtgctgtct
    18721 atgcttccac gtttgttcaa gcttcgtttt tatccaagct atgcagcctt tacattcccg
    18781 cttgttatct ctgcaacagc tatatttact actgttcatt acttcaacag tttaggtatc
    18841 tatagtagcg tattggattt cttaaaagtt gcggaatgtc tgtttgcaag tgtagttgtc
    18901 ttctacgttc ttgctcatta cgtacgtttc ttaattaaag aacatagcaa acatggaaaa
    18961 tttgtttcta aaaaaatcgc ttaataatcg attcaatagg ttgtgaaaaa gctgttctgc
    19021 atcaagtaat aagaacggcc aaacaaaaac agctgttcat gtttttgaat tggttgggct
    19081 tattaccgca gatgcaagct tttgaacacc gtttaccaag aggtcgtaaa agaagtggcc
    19141 agcttcaaga aataagaagg aatttacgaa aattgcttct caaatttttg tgaaatttcg
    19201 gcttatttcc gaaaaagcta cttctggaac accgtttacc aagaggtcgt gaaaaagccg
    19261 cttagtttcg agtattaaga aaaattttgt gaaaatggct ttccacattt ttgcataaat
    19321 ttggcttaat accgagaaac tggcttttga acaccgttta ttcgaaacaa gaggtcgtga
    19381 caagactttt gtcacgacct cttgttcttt tgtcaaaata ctggtttagt gctactatgt
    19441 tcgagtatgc ttttagtatt tattgacgaa aggaaccgat caaatgaaat cattgtcaca
    19501 tccaataaaa tctgtaaagg attcagcggt ccgcgaaatc ttacccggtt tactgctttc
    19561 ttttgccatc gctgccttca gcaggcttct tgctatttat ctgccacagt taggtggagc
    19621 gactattgct attttattgg gtattttatt aggaaatact ttttttaaac agcctgttct
    19681 agcaatcggc acaaaatttg ctgaaagcaa actattagaa ttctctgttt ttttactagg
    19741 tgcaactgtc acagctcaaa cgattgctca aattggtata aaaggaattg tttttgtgtt
    19801 actgcaaatg tcagtcacta tcatcggtgc ttacttgatt ggtaaaaaac tgcaattcag
    19861 cgatacttct tctttgatga tggctggagg aaacgctgtt tgtggttctt ctgctattgc
    19921 ttcgatcgcc ccttccatcc atgcgaaaga ggaagaaaaa ggacagatca tcacactagt
    19981 caatctactg ggtactgtga tgatgttgac tctccctttc cttggattac agttgtttgg
    20041 tggaaatctc attgaaaaaa gtgcactttt gggtggcaca ctccaatctg ttggtcaagt
    20101 agtcgctggg gcaagcttac ttgacaattc tgttgtcgaa ttcgccatgc tatttaagat
    20161 tctacgtatt atgatgctcg ttgttgttgt ctatctgttt gaaaaattca tgcacaagaa
    20221 acaaccagct ctgtttgaaa cgccaactga tacgcagaaa aaacgaaaat taccacttcc
    20281 ttggtatgta ttagggtttg tgatcttttg tttggtcaac agcttgtttt ctttacctgt
    20341 agttattgac caatcggcac attttatcag cagctggttt gagatcactg ctttagcggc
    20401 aattggtctg cgtttagact ttgcaaaatt catgaaagaa ggtacacgct tcttatctta
    20461 tggattagct gtcgggcttc tccaaacagt gatggcttta ctatttattt ggctgatcaa
    20521 agtttagaat gaacatgaaa aaacagttgt gattctcgca tggaacaatg tccgaatcac
    20581 aactgttttt aattttgcag atatccttct aacaacaaca attggcgttt gatttcaacc
    20641 ccatctattg cgtttcccat atatcctgtc agttttccat tttgcccgat cactcgatga
    20701 caaggaataa cgattggcaa tggattggtt cgatttgcct gcccaatcgc tcgcacagct
    20761 ttcggactat caacagcaac agctacttct ttatacgttc ggatttctcc ataaggaatg
    20821 gtcgacaaag ctttccagac attttgctga aaaggcgtac ctctctttat agataaagga
    20881 acatcaaatt cttttctttt tcccgcaaaa tattcttcaa actgttcttg tgtgcgcgtt
    20941 aaaatttgct gattcgctga ttcgctttct gaaattggct gaaaagatac agcagtcaat
    21001 ccggattcat ctgcatctaa ccataaaaag ccgataggtg tgtgtatttt cattttgttt
    21061 gctcctggtc agtagactgg aacttcctcc tttttctcta tccaaaacta cttgccaact
    21121 aataaaaatt gttcttaaaa gtttgataaa ccgaggaaac atggtaaact aaatacgtta
    21181 gtttaccaaa gaatagctgt tcttttccat aaaatcaaat ttaaaaggtg ttatttaagg
    21241 tttattaaat tttgaatgta aaccatatat aaacatacga ttgaaaggat agaaacgatg
    21301 aaagtatcaa ttgttgtccc atgttttaat gaagaaaaaa ctgttcctct tttttttgat
    21361 gaggttgaaa aattcaaagg tgcccatgag ttcgaatatt tgtttattga cgacggatca
    21421 aaagacggta cgttagcagc aatcaagaag ctagcctcag cttatcctta tgtccgcttt
    21481 gtctcatttt ccagaaattt tgggaaagaa gcggctctgt acgctggatt gcaagcttct
    21541 acaggagatt tagtgaccgt gatggatgtt gatctgcaag atccgcccga actgcttcct
    21601 gagatgatca accggatcac tacttctgat gtcgatagtg tcggcacccg gcgttcgact
    21661 cgtgaaggcg agcctgcgat acgcagtttc tttgcgaaaa aattctacca gttgatcaat
    21721 aaaatcagcg atacagaaat ggtcgatggc gctcgtgatt tccgcttgat gactcgtcaa
    21781 atggtggatg ccgtcctaga attaacagaa tacaaccgat tttcaaaagg attatttagc
    21841 tgggtcggat ttaaaacaga atatatttct tatgaaaacc gcgaacgtgt ggctggcgaa
    21901 acatcttggt ccttctggaa attattcaac tactcgattg atggtatcgt gaacttctcg
    21961 gatgcaccgt taacgattgc ttcatttatc ggcgctttgt cttgtgtcgg ttctggtatt
    22021 gcaattttgt tcattatttt gcgggcattg ttgtttggtg atcctacatc aggatggcct
    22081 tccatggtct cgatcttcct gttcattggt ggaatccaat tgttatgtct tggaatcatc
    22141 gggaaatata tcgggaaaat cttcttagaa acgaaacagc gtcctgttta tatcataaga
    22201 gaaacagaaa aagtgaagcc aaatgaattg aagcctcacc aataatatac gtcaaatgaa
    22261 gtaaacattt ttttaaatga aaaaggactg tgacaaaagt cttgtcacag tccttttttc
    22321 cgaataaatg gtgttccaga agtagcttct tcggaaataa gccgaaattt cacaaaaatt
    22381 tgagaagcaa ttttcgtaaa ttccttctta tttcttgaag ctgaccactt ctatcacaac
    22441 ctctttcata tcttattact tcttcattgc tgcttttagt gctgctgcta atgggctttc
    22501 ttctggttct tctgcttgtg catatttttt cagcaagcgt cgttcttcat gtttggtcat
    22561 tttcttcttc tgctcttttt tatcaagcat tttttctgtc gttccatcgt atttacaacg
    22621 gaaataagca ccgtttttac cttcgatgat ttccattttc cggtgacatt gcgggcatcg
    22681 atgattagag acttttggat cttttcttct gcggtagttg caatctgaat tggtgcagac
    22741 atagattttg ccgtcacgtg tgtttttctc gcgcagattg gccccacatt ctgggcattt
    22801 cttttgggta atcgagaaat cttgatattc ttgtttgctt gatttgatct cattcaccaa
    22861 gcgttttgtt tctttttcga ttccattcaa gaaggttcct gcttgtttct ttcctgcagc
    22921 aatagcttca aggtcttttt cccagctttc tgtcaaatct ggtgttacta aagagggatt
    22981 taccaatact aataattgct tacctttagg agatacttgc agtccttgag gggtacgttc
    23041 catcagttca gatttgatta gtttctcgat aatctctgca cgcgtagctg gggttcccag
    23101 actgtatttt tccatttgac caagcaagct tgcttctgac aatggtttag gcggtgcaga
    23161 tagttctttt ttgatggtga aatcgggatt gattctcatt tctttttccc atttgactgt
    23221 ttccgtctca gtttcagttt cgcctttcca tcctgcttgg acgacacgat tttgccgaaa
    23281 aatgaatcgt tctttaccaa attcaaccgt aacttttgtt tggctgactt tatggggttg
    23341 agcaaacagt cctaaaaaac gagagacaat catttgatag attttttgct cttcattact
    23401 taatttttca taacgtgctc tgttttcagt tggcaaaagt gcatggtgat cggtcacttt
    23461 actgtcttgg aatacttttg tctgttggac gatggctccg tttttcaaat actgcttgac
    23521 ctcaggagca aagtcgctga ctgcttgcaa tcgttctttc atcgtacttt tcatgtcatt
    23581 tgtcagatat ttgctgtctg tacgcggata agtaacgatc ttatgggtct catacaaact
    23641 ttgtacaaga cttaatgttt tctttgcaga atagccatag cgttgattgg cttctctttg
    23701 gatctctgtt aaatcataag gcaatggcgc agattccgtt tttaattttt cttggacttc
    23761 tgtgacagtt cctttgcttg tactgatcaa ttgaacaagt ttttgtgctt cttcttgtgt
    23821 ttttaaagca aattgatttt tttgaagcat tttggcttgt tcttttccag cttgcaacgt
    23881 gatcgtgaaa tacgtttgtg gacggaactg ctcgattttc ttttcttggt ctctcactaa
    23941 tgctagtgtc ggtgtctgca cacggcctgc tgataaatta tccgcgtact tcacagttaa
    24001 ggctctggtc acattcaatc ctaccagcca gtccgctttt gcccgggcaa gagcagattc
    24061 atacaatgca tcatattctt tcgcaggtct tagttgcttg aatccagttt tgattgcttt
    24121 atctgtttga gaagagatcc ataaccgctt cactggttta ttgaaatgca catactctaa
    24181 gatccagcga gcaacaagtt ccccttctct tccggcatct gtcgcaatga ctgcttctga
    24241 gacatctttt cgctgagcca gctgcttgat tgcttttaat tgatgtcctg ttttaggaag
    24301 tggtttgatt cctagttttt tagggatcat tggcaacgtg tccatttgcc agctctgcca
    24361 ttccttattc agatcttccg gcattttcaa tcctaataaa tgaccaaggg cccaagtaac
    24421 gatcaccttg ggtccttcat aataattttt gtgcttttga ttagcaccaa gcaccttgct
    24481 taggtctttc gcaacgcttg gtttttccgc tagaattagt tgtttcataa aattcctttc
    24541 cgctttctac tgtgatgggc tgatgatttt tcaacaacgc aagtcctttg tattgctgta
    24601 aatcatcgtc acactcttca caccagcgct catctccgtc attccaaaag gcgctgagaa
    24661 agttactttt tgcattgata tattcataat tttgatggat ttcgttccat tgtttttcgt
    24721 acgcttgtcg tgcttcttcg aaagactcga atgtttcttc tgcttcaata tcttcttccc
    24781 agtcttcaaa aaaccaccaa ggctcattgt ccccgaacat ggtaattact tgatacatac
    24841 tcgtgctcct tctttcagct tttctagact tatcttagtc acttttcaag aaagttgcaa
    24901 gaattttctc ttataaaagg atcatttaat gaacatcttg aaaatgatat aaatgaatct
    24961 gattgtttaa ggcaaagtag cgataaagtc attgatcatc caaaaatagc tgtcctctgg
    25021 atcgattgtc gattcttttg taaagtatcc taaaaaacgc aaggaaagat agccgtggat
    25081 catactacat aattctctgc ttcggtggac tttttcttct ttcgttaatt gaaaagcctc
    25141 aaagatctgc aaaatgatct ggttcgtttc atggattccc tctaataaaa ctgcttcatt
    25201 ggtgtggggc acactgatca gtaactcata cactgcttga tttgaaaaag caaaggatcg
    25261 ataagtttct gcatagatct gcagtgcttc ctgaccactt tttcccacaa gagcccgacg
    25321 cagctggtca ttaagttcct gcagaagttt cgctgttagc gctgttttga catcacgaat
    25381 atttttgaaa tggttataca gcgagggagc cttgatatcc aagcgttttg ctaaatgctg
    25441 aaaggttatt tgctgaacat ccatctcttc tgctagttct cgaaagcagt cgatgatttt
    25501 ctcttgagac agatttcttt ttttcatttt catgtttcct ctcataaaat aaatccttca
    25561 ctctttcagt ttaccacgaa aaagaaagag aaaaaagaga ctttcattga taaactacat
    25621 attgtagttt ataacaaaaa gctgtagatg aaaattttca gaaagaagga gtctaattgg
    25681 ctgcaagaat aaaggaaaaa ttatttagga aaagagaaac ttgggaacaa aacttgtttg
    25741 tcttatggtt tggaacattt atggctggta tcggatttag tttagtcatg ccttttatgt
    25801 cactttacat agatacgtta ggtaattata gtacgtcaca attgaacttt tggagcggat
    25861 tgactttttc atctactttc ttggtgacta cgctgatctc tccttggtgg ggaaaattag
    25921 cccaccaaaa aggaagaaaa ttgatgctgt tgcgtgcttc attaggaatg gcaatcgtca
    25981 tttctttgat gggttgcgtg actagtgtgt atcaattagt cgcattgcgt ctgcttcaag
    26041 ggattttttc tggttatatc agtaatgccg ctgcccttgt cgcaactggg acgccaaaag
    26101 aaaaaagtgg tcaagttctt ggaactttag caactggttc tgttacagga acattacttg
    26161 gaccgcttct tggcgggatc tctgcttcag cgtttggcta tcgccctacc tttttcatta
    26221 cagggatcat cttatttttc gtcttcttgt tgagtctgtt tttcgtccat gaaaaatttg
    26281 tcccagtgaa aaaagaaaac atggtttctg ccaaacagat tttcaaagac ttgaaatatc
    26341 cacacgtcgt catcggtatg ttcgtcacaa cgatgatcat ccaagcatcc aacaattcca
    26401 ttagtccaat catcagtctg tacattcgcc aattgctgca tggacatggg aatgttacgt
    26461 tgatcagcgg aatcatcgct tcgatacctg ggattgccac tttgatagcc gctccaagat
    26521 ttggtcgctt aggtgacaag attgggagtg aaagaatact tgcgattggt ttgggttttg
    26581 cgattctggt ttatatccca atggcattcg tcacgaatgt ttggcaatta gctgccttac
    26641 gttttttgat gggtatctct gatgcttgtc tgctccctgc tgtccaagca ttgatcacaa
    26701 aatattctcc tcatcaagct gctggacgga tcttcagtta taaccaatct ttccaagcaa
    26761 ctggtaacgt agtaggacct atgatcggct ccagtgtttc tagtgcattt ggttatcgtg
    26821 gcgtctttct ttcgacttct cttcttgttt tggtcaactt cttgcttgta cgacacaata
    26881 cacaagagat ccatcagcaa gaaactgcag aagaaaaagc ttcaggagtc tccatatctt
    26941 cagggcactc tccttctcat agacaataag cgtaaatgaa aaacactgct tgaacagttg
    27001 tcacagactg tccttgcagt gtttttgttt aggcctgttt tttcaagaac tcagataaga
    27061 ggaataatcc cttttccaag gtttcttttt tacaacagta acctagtcgg gcatgcttcg
    27121 gtaaatcaaa ggcacttcct ggtactaata gtactcctgt ttcttctaat aaattgatac
    27181 aaaatgtctg gtcatcttct tcgatggcta atttaatgaa agaagtagag acgtaattgg
    27241 gagcgacaag ttcaactttc ggttcattgg ctacccattg ttttaaaatc acaaggttct
    27301 ctgtaatgat ctttttgttt cgctccaata ttttttcttt attcttcaat gcatgtacag
    27361 caagatcatc tgacaggact ccgccgcaaa tcatcgtgta gtctcgatac tttcgaaaaa
    27421 cttctgccaa ctcaggtcca gtagctgtcc agccaatacg aatacctgga atggagtagg
    27481 ttttggatag ggaattggtt gctatacctt tttcatagac atctacgatc gacaagaatt
    27541 cacctttatc cgttaaaggc gcatatactt catctatcaa tacatatgca tctactgtac
    27601 gagcaatttc tgcgattttt tctaaagttt tccgatctag caatgtgcct gtaggattgt
    27661 ttgcactatt caaacagatg atttttgttt caggtttgac taaggcttct agctgttcta
    27721 aatcaaactg ccaatcttct tcttccttca aatgaacaaa gtcaacagcg gcacctaaag
    27781 atttggggat gtcatataat tgctgataag taggaagcat cgaaacaaca tggtctcctg
    27841 cttccactaa cgcgtataga gctaaaagat tagcaccagt cgctccattc gtttgtaaga
    27901 tgttttccgg atcgacggtt tgataaagag aagcgacttc ttgtttgaaa acatctgatc
    27961 cttcgatcca gccatagtcc aatggttcgt ttttgcgttt ttcgaaaaat tcacttacgc
    28021 tagtcccatc taagccaacg agttcgtcta atgtcaatgc ttcgatcgag ctttgtgcaa
    28081 tatcatatac cgctttcttt tcccatttat ttagccattc ttctacaccg aaatttgcga
    28141 ttttcatgtt tctttccccc ttatatcttg atccagccta cagcaagcaa cccgattgaa
    28201 agcagtgcgg ccacacaaat cagcccaatc attacttttt cttttcccgt aatttgatgt
    28261 ttggtttcac gacaagcgat ccagtagaag caaaaaccag gaagataggc aatactacat
    28321 aaaaggacat aagaaaatcc tgctaaaatg atgcccatca attcaaaagc tacagcaatc
    28381 ccaccgatca ctacttgttt tttgattcct tcttttaaag aaaactggac ttgatagatc
    28441 ccgacaagta gataacaaat caaaattgcc gctgtacata aagaataggc aaattgatag
    28501 gcataatcag taactaagaa agtcaataag aatagattag tcaagattgc agtaacaact
    28561 aacgaataag ttggggcatt ttttttattc gtttttcccc aacctttcgg caacagaccg
    28621 tctcgagcca tcaacatcgt tgtttctgct gggagcatcg tccaagacaa ccaagaacca
    28681 atgatcgaaa taatcaagcc gatattgatc agcgctgctc cccaatttcc cacgattcct
    28741 tttaaaatat ttgccatagc aggttgtgaa atagttgcta actcttcttg agataagacg
    28801 ccgtatggca agatcgaagc aaggatatag ataaacaata aacaaagcag accaatgatc
    28861 gatgcttgct gggcttctga acgtttcttc gcgcggttgg ctaaaacact tgcgccttcg
    28921 atccctacaa agacccacat cataaccatc aaacaacctt taatctgcaa ccagatcgtt
    28981 ccttgctgcc ctgttccatt cactagatta tcagatacgt taccccaaaa atcagcagtg
    29041 aatatattca ctttaaatgc gataaataca aatattaaaa ataggaataa tggcactaat
    29101 ttacagatcg tcacgattgt attgatgacg ctcgctcctt caactccatt gtttactaat
    29161 aaagtcagac cccaaataaa aatacttgca aataaaatag aaggaacatt ttgtccacct
    29221 ttgaatatcg cgaaaaattc tcccatggcg ctcatcagca tcgttgcaaa agcaacattt
    29281 cccagccacg cagacaacca gtaaccccaa ccactgatga agccacctaa tttaccaaat
    29341 gaagcttccg cgtaaccgaa aataccacca tctagatctg gacgtttttc tcctaaatga
    29401 ttcagcgata ataccaaagc taaaatacca atcccaacga ttatccatga aaggatcgct
    29461 ggccctggag ctgcagaact agccagatca cttgtgatcc caaacacacc gcttccgatt
    29521 gacgaactga caaccagagc aaccagtccc catttgctaa tacccgttga tttcttttcc
    29581 atttccatca ccctcactta taaaattgaa caaatcactt gcaaaagatt tccttctatt
    29641 ttgcaactgc tcttgcttaa caaaaagcaa ctttattcat attattggat attatgaact
    29701 ttttacacaa gtatttcaag tataaaatga ataaaaatta attttattgc aaaaaaacag
    29761 ctatgctatc caaaagaaaa ggtgtttctt ttgttagcca tagctgtttt gattcattta
    29821 atatcgctta aacgtattgt aaaacttttg tttcttgata tgcgtggtcg atcaaaccac
    29881 cacccagaca ttccatttca tcataaaata caactgcttg tccaggagtg attgcacgta
    29941 caggttcgtc gaatacgact tctgcatgat tatcatccaa taagcgaact gtcacaggaa
    30001 cgtcttgctg acgataacgg aatttcgctg tacacttgaa ttcttttggc attggttcat
    30061 tcgtcgtaaa gtggatttca cttgcatcca agcttgtggc atacaatgca ggatgatgga
    30121 acccttgccc cacatataat gtgtttgtcg ctagatcttt tcctacaaca aaccagggtt
    30181 cttgcgaatc tcctccgcca ccgatcccta gtccttgacg ttgaccaatc gtataataca
    30241 tcaagccagc atgttgccct ttgacttcac catcaagagt gaccatattt cctttttttg
    30301 ctggcagata gttgctcaaa aattgtttga agttcttttc accaataaaa cagattcccg
    30361 ttgaatcttt tttcttagca gtcgcaaggc ctgcgcgttc agcaattgcc cgtacttctg
    30421 atttttccat gccgcctaga gggaacatcg tttttgaaag ctgttcttgt gataattggc
    30481 taaggaagta agtttgatct ttattattgt ctactccacg aagcatgtgg accacgccgt
    30541 tttcatcgcg agtgacttgc gcataatgtc cagtagctac ataatcggcg ccaagatcca
    30601 ttgcataatc caagaatgct ttgaatttga tttctttgtt gcacatcacg tctgggttag
    30661 gtgtacgtcc tgcgcggtat tcggctagga aatattcaaa tacacgatcc caatattctt
    30721 tttcaaaatt cacagaataa taaggaatcc cgatttgagc agctactttc gctacatcct
    30781 tataatcttc cgtggccgtg catacaccgt tttcgtccgt gtcatcccaa tttttcatga
    30841 atattccgat cacgtcgtat ccttgttcct ttaacaaaag tgctgttaca gatgagtcga
    30901 caccgccgct catccctacg acaacgcgtg ttttgctgtt gtctgtcatg atatcaccat
    30961 catttcaatt agattctgaa acatctacga gttgaaggtc gcaacttttc agtattttac
    31021 attatacgtc atatttctga aaatttcatc ccttaattat caagtcgtaa aaatactgtt
    31081 ctactggacc tattcagtac acaaacatga tagtcaacca aaaaatcact catcttttga
    31141 gcattcgata taaaaaattg gcatactcat aaaaagggcc agcctttcgg caataaggaa
    31201 taattttata aattgtgaaa aactattttt caaaattgct tcttatcgct taaagctaca
    31261 cgtctcattt acaacctttt ctttttagat gttatgagtt gctcagataa gtgattttgt
    31321 ttactctaag aaaaaaggga ggcaaaagat acatgaatta ctttaccagt gatatgcact
    31381 ttttccatga acgcttatta ggaaaaaacg actttgctcc gcggctcttt gcaaatgtgg
    31441 atgaaatgaa ccaacagttg atcactagct ggaatgcagt aataaaagaa accgaccatg
    31501 tttatcatct aggcgacctt gctatgcatc cgcaatatga aaaagcaaat gcagaaattt
    31561 tggaactggt cactcaactg caaggaacaa tccacttgat caaagggaac catgacagtc
    31621 gcgctttttt ccgttattta gaaaaaaatg atcctaggct tactgacgga agtcccaaat
    31681 tttattttta tgatgtaggt gccatcgtta aattcgacca tcaacaatat tacttgactc
    31741 attatccgat gttgctcggg cctaacgaca ctatccgcaa tcttcatgga catatccatc
    31801 attacagcgt acctatcgag aacgatgtca atgtaggcgt agacgcaccg gaaagggaac
    31861 tcttaaagga aaaactacca tttggcactc cgttatctga gcaacaaatc aaagaaatct
    31921 atgaagcaaa gaggaagtac gataggtcgt gaaaaaactg ccctatatca agtattaaac
    31981 aaataaagat aattactcat atttttcatt tgagtaggct tattgccaca ggaacattag
    32041 gatcagaaat ggagttgtaa caagacttct gtcacaactc cattccatac tattcgtctt
    32101 tttactcatg gtgttctttt accaattttt tctgtaattc tttatcataa tttcgagcag
    32161 ctgacgttaa aaataaaacg attccgcata ataaaatccc gattccagaa aacaagaaca
    32221 ttttttctac ccctaaacga tcagctaatg gtcctgcaaa taataatcca attggacctg
    32281 ccaggttcat caaagagttg aagttcccta agacacgacc taaaacattc gattcataac
    32341 tctgctggat cattgccatc agcagtgtat tgaaatatgg cgttgcacaa cctgctcctg
    32401 cattcaagat aagaaagtac aagaaccctt gactatcgtt tggacccaat ccgcttgcac
    32461 cgatcgtcag gcccataatg atgtaggcta taataatagg tttcattcgg tctttccatg
    32521 ttcctataaa actgatcagt gcaccgccta agagcattcc gactgcgtag actacttcca
    32581 ctgctcccgc ctgtccaacg gaaccaccaa agtaatctag cgtcatcaat ggatacagac
    32641 tgattgctgg catgaacaac agcatcacaa atgcaccatt gatcgttatg taccataacc
    32701 ctttgttatc catcaattgc tgcagcccaa attttgcatc tttaaaaata gtaagcggaa
    32761 cttccaatat ttcaggagaa acttttggga tcttcacaaa aatcaataag ccgacaccaa
    32821 aaactgcccc caatacatct aataaaataa ggtaattgac aggaacgact gaaaacaaag
    32881 ccgcacctag agctggcgca atgatgaaat tcgctgattg gaccattcct aactgtccat
    32941 tcgtccttgt tatgtgagaa gatggaacga ttgtcggcat aatcgactga tcgttggcat
    33001 ttggaatgtt tgtgcgaccg aacgcataaa caaagacaca aaaactagcc aaatcgggaa
    33061 ggattctgaa atcgttccga ctactgctaa aataagcgcg aaaatcgcta caataatatc
    33121 cgtgacaatc aaaagagctt ttttatccca gcgatccact agcggttcta caaatgggct
    33181 tagtaaaacc atgggaatca ttcctagtaa agtagcaaaa ctcaaaattg tcgccgaacc
    33241 ggtttctctt gtcaaatacc agatgatcgc atattggacg accatactag tgattcctga
    33301 caaaaactgt cccgataaaa agaacaaata atttctcttc caattcgtta aaacgaccga
    33361 ctgttcattt tccataaaca tccctctttt ctttttcatt ttgtatagcg tttgcacaac
    33421 aatcattata cgggattctt ttttcaaaaa ataccttttt ccctaaataa caatcgtttc
    33481 aatttaaatt tctttactta gaaacaataa atcagcaaaa tattaaaaat aacaacatgt
    33541 gttaaattta aaaataaaaa agacaactaa tttgcgttgt ccttacaaag ttagtcatct
    33601 aacaataggc cgtttcaaaa ctagttgtct ttttatatcc acagatcatt cgactttttc
    33661 gaataaccca cggctaatca tcccatccat cagaaaataa aatttatctt ggctcatttt
    33721 ctgttttgga tctttgaaaa tattgactgc tttcaatcca tttgctgtag tgatcgacat
    33781 tttcaatgtt tgaatatctt ttgatacagt gatttttaat ttgaatcctt ctttgctttg
    33841 cggcgtggca tctaatggtc ggatcaattg ataattgcct ccgtttgttt ctgtaaatcc
    33901 attatcgcgc aatgtatatc tttttgcatc aggatgcaaa cgatagctaa ttggtgcgcc
    33961 cagtaccgtt gctgttgttt caaatgccat gattttcacc tcgataaaat tagtttctct
    34021 ttattataaa agtttatcct gatttttact aggtttttca gttaagttcc ctaaaaaatg
    34081 aaggcgttct ctcagacatc tgttcatata agaatgactt cactagttat tttttgacag
    34141 cacgaactaa ttgttcaagg aaatactgga tgtcgtcttc ggtatttccc aaaccaaagc
    34201 tgatacggat ggattctttt agtatcggtg tatcttctcc atacattgct tctaatacgt
    34261 gtgaaggctc gatattacct gctgtacaag ctgaaccagt agaaatagcg accccattaa
    34321 gatcaagctt catcagtagc aaatcatttg cttcgccaat taagcgaaga ttcaacacat
    34381 gagggagttt attcgttaaa tcaccattta cttgataagg gatttcgttt gcttctaatg
    34441 tatcaagaat caattgctgg aatcctttat atttgttgtt acgtgcttca cgttcttcag
    34501 gtgacagcag ttcaactgct tttgccatac cccagatccc tgctaaattt tctgtacctg
    34561 cacgccgctt ttcttcctgc tccccgccta aaagcaatgc agggatattt actccgtctc
    34621 gtttatataa gaaaccgacg ccttttggcc cattgatttt atgagcagag atacttaata
    34681 aatcgattcc taattcttct ggatggatcg tttggtttcc gtacgcttgt accgcatctg
    34741 tatggaaata agctggatga tccgctaaaa gttcaccgat ttctttgatt ggcatcaaat
    34801 ttccgatctc attgttccca tacatcacag agaccaagat cgtatcttct cgtaacgctt
    34861 ttttgacctc ttcgatcgac agattccctt tttcatctac aggcagatat gtaacgtcaa
    34921 acccctttgt ctctaaatat ttcatggtat taagaacagc aggatgttcg atagctgtag
    34981 tgattagatg tctgccttct ttttgacacg agaacgctgt ttctaagata gctgtattat
    35041 ccccttctgt tcccccactg ttaaagatga tctcgtgagg ttttgcttgc agactgtctg
    35101 caatgatttg tcttgctgtt tccaattttt catgcgcgtg gcgaccaaat ccatgtatgc
    35161 ttgaaggatt tccaaacgtg tcttgcatga ttgccgtcat cgcttcaatt acttgtggat
    35221 gcatgggggt agttgccgca tgatccagat aaatagtttt cacttcattc atcccttcca
    35281 aattattgct aggcacattc tagcataaaa tagcgaacaa accaaagaag agctcatttt
    35341 tgtctagagg acgtttcatg ggcatagaaa aaaggagcta tgacaaaagt cttgtcgcag
    35401 ctccttgaag ctgctcactt gtgtcacaac ttctttccct cttttttttg tttattcgaa
    35461 ttctttttct tccagacgga ataacggact catcggtgta ttttcatgga tgcgtttgac
    35521 cgcttctccc attaattctg aacatgtaac gattgttaag ttttctggat gacgattttc
    35581 ttctgtgaaa acagaatcag tgatacaaat atctttgatt ggtgcattgt ctaaaatact
    35641 tttcgcatga tcggacaata atccatgtga cgcacaggca tatacttctt ttgcgccgtt
    35701 ttcttttaat acatttgctg ctcgtgcaag cgttgctcct gtgttcaaga tatcatctac
    35761 catgatacat gtctttcctt gaacatcacc gatcacataa ccaccctcag ttgaagcatc
    35821 atctgcatga tctacgatgg ctaatgtgct gttcaaatat tctgaaagac tacgtgcacg
    35881 ctgaacaccg ctgttttttg gcgaaacaac tacgatgtca tctcccgtca gacctaattg
    35941 acggtaataa tgagcaaaca acggcatcgt aaataaatta tctacaggaa tatcaaagaa
    36001 tccttgtact tgaaccgtgt gcagatctaa agtcagtact cgagttgccc ctgcttcttc
    36061 gatcaagtta gcgatcaatt tcgcagtgat cggttcatga ggtttcgccg tgcggtcttg
    36121 cctagcatac ccatagtaag gcaatacgac attgatcgtt ttcgcacttg ctcgcttcat
    36181 tgcatcgatc atgatcagta gttccatata gtagtcattg acaggtgcat tcgttgattg
    36241 aacgatatac acatgatccc ctcgaatact ttcttcgata ttgatggaaa tctcgccatc
    36301 actaaattgc ttcacgacgc ttttacctaa ttctgttccg aacactttcg cgattttttc
    36361 agctaatgga cggttgccat tcaaactaaa aatcttcaac gtgtcatcct gatacttatt
    36421 actcatgtag tcctccccaa aacttctcta ttcttcgata gtttaacata tttttccaag
    36481 attttctgtt aatttcagca aattcttaag gaagtgaaac tgttccgtta ctccaactgg
    36541 caggaatgac tttatgataa tcgccccagt tgtcgtgtac tttgtaataa cgttctcctg
    36601 tttcagtttc aaaataagcg tacgctgtca cccaatgatt gccatatgta ctgccaagta
    36661 ctttcaaaat accaatcatc acaggtttgc cttcacgtat acgttttgta gctcgctgcc
    36721 atgaacctag aagagttgct cgtgcacgct catgattgcc attcttcttt aaaaaactag
    36781 aaatccctgt actaacctga aaaggaatcg taggaagtcc tagtggttgg atctggctac
    36841 gcaatgcctt cgtcaaaacc aacgaatcag ccgtattttt cttgcgaatc tcatttggaa
    36901 gcatccactc cttacgatag tcttgataat aggcaaggag aactgctgcc gcgtaagtac
    36961 cacaaagata gcctgagggg gtagcccatt tcttatacct caaaaaacgt tcttctggca
    37021 atcccaccca gcaatttgcg agttcctttc ctgacctttt ttcttcgatc aaagcgggaa
    37081 tatcttcttt tctgttgatc catctagata actcgattgg ctcttcattg atcagcttcc
    37141 attttttaca agaaagaccc tcttgataag tatattttgc tggagaatat tctaccggat
    37201 gtcctgattg atcgataatc acataacttt gatcttcaaa aaccagagct aaaaaaagca
    37261 atttactttt tcttgactgc agctgctgag tgctggctaa ttttttaatt tttttatcta
    37321 ctttgaaata taaaggttta tccactactt gattcagttg ggatcgcctc ctttttttca
    37381 ttataagtga aggattgaaa aaaacaaatc agtttgattg ttcgaatttt caatttttta
    37441 tgttctattt gttaattcct tcattttgta agataatggg cacacgaaac aaaaaaggag
    37501 cgatcgatga atgaacaaag aacgattgaa acaagatttc tatgaagcag tcaatgaaga
    37561 atggcaaaaa acagcaaaaa tccctgcaga taaaccagct acaggcggtt tccaagattt
    37621 agttgacggg atcgaccaac ttttgatggg agaaacagac gatctgcttg cccatccaga
    37681 aaaagtgtct tcagaaaaaa tgaaacattt ccttgcatat tatcaactgg caaacgatta
    37741 tgaccgaaga aatgagttgc atgctcaacc acttcaacct ataatcgaaa aagttgaatc
    37801 attgcagtct ttcgacgaat tgaatgagca atttccagaa tggctgttgg atacattacc
    37861 attgccattt aatctggatg tagatgcaga tatgaagaat gcgcaaacga acgccttctt
    37921 tgcttatccg ccttctttat tccttccaga taagacgtat tatgcatcag accatcccaa
    37981 cggtgcacaa ctaataggcg ttttctttga tatggctgtt cagttattag agcttgccgg
    38041 caaagaaaaa agtcaggcag aagcaatcac ggaacaagca gtgcaatttg ataaattgat
    38101 tgctcctcat gtaaaaagtg cagaagaaaa cgcagattac agcaaaatgt ataatccgca
    38161 atcttttgat acatttattc aatacacaga taaactggac ttgaaaaaac ttgtcacggg
    38221 tttgattggg acaactccag ataaagtgat cgtaactgat ccagtgtact tcgatcattt
    38281 gaatgacatc ctgacagaag ctcattttcc gttattcaaa agctggatga tcattaaaac
    38341 agtacgttct cttagtggtt atctatcaga agaattccgc caagtcagcg gaatctattc
    38401 tcgcgtattg tctggaacag acgaagcaat gcctcagaaa aaagcagcgt attaccttgc
    38461 ctctggacaa ttcgatcaag tagttggcga ttactacgga aaaaaatatt ttggcgaagc
    38521 tgctaaaaaa gacgtagaac aaatggtgaa aaaaatgatc gccgtttata aaaaacgtct
    38581 agaagaaaat gactggcttg gggatgcaac aaaagaaaaa gccgtcataa aattaaataa
    38641 cttaggtatc caagtaggct accccgataa gatcccagca ttattcgacc agttcaaaac
    38701 agtacctgca gatcagggtg gtactttgct ttcaaatact cttgttttca gcaaactcac
    38761 attaaaagat cgtttcagca aatggaacaa accagtggat cgttcagaat gggaaatgag
    38821 tgctgacacg gtcaatgctt attatcatcc atttcggaat gtgatcgtct ttccggcagc
    38881 gatccttcaa gcaccatttt acagtctaga acaatcaagc tctgctaatt atggtggaat
    38941 cggagctgtt atcgctcatg agatttccca tgcatttgat aataacggcg ctttatttga
    39001 cgaatatggc aacttgaaca actggtggac agaagaagat cttacacaat ttcaaaacaa
    39061 agcacaagca atgatcgaag aattcgatgg tctgcctttt gctgacggaa aagtaaacgg
    39121 aaaattaacc gtttcggaaa atattgctga tgcaggcggt ctaagctgtg cattggaagc
    39181 agcaaaaacg gaatcagatc tttctatcga ggaattcttt gtcaattggg caacgatttg
    39241 gcgtacaaaa gcaaaaaaag aataccaaca acttttactg caaatcgatg tccatgcccc
    39301 tgctaaactc cgagcaaacg tgcaaccaaa aaaccttgac gaattctatg aaacatttgg
    39361 tatcacggaa caagacgcta tgtatctagc gccagaaaaa agagtgcgaa tctggtaaga
    39421 ggttgtgcca gaagtggtca gcttcaagaa ataagaagga attggggaaa attgcttctc
    39481 aaatttttgt gacatttcgg cttatttttc gaagaagtta cttctggaat accatgtatc
    39541 agaggttgtg aaaaagccgc ttagtttcaa gtagtaagaa aaattttgtg aaaatagctt
    39601 tccacatttt tgcataaatt tgacttacta ctgagaaact ggcttttgaa caccgtttat
    39661 cgagaggttg tgaaatcagc gtcctgacct gagtattaga gaaaaaacgg aaaaatagtt
    39721 cctcatattt tgccgtttgt tgagctaata ccgagggtca gctgattgaa caccgtttag
    39781 tggagaggtt gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa tcaaaagcag
    39841 caaggagaac ctcatctata aaaagataga aggaagtgag acatctattg gtctcatttc
    39901 cttctatttt tactttcctc agtcaattgt tttacatcat aaaaggagaa attccactta
    39961 tttttttcgc tgtttcatga cataaacaac tacaccgatt aacaaaattc ctccagctaa
    40021 tgctagcaac gggttattaa attctcccgt ttttgggagt ccttgagtgc catttttttc
    40081 actttctttt gctgtcctgt ccggatgaga aggttttcca tttggtgatt catttggtga
    40141 ttcatttggt gattcatttg gtgattcatt tcctggattt tctctttctg gtttgtcatt
    40201 tcccgggggc acatcggcag tttctcgcac agtgatcgct ttttgctggg taacagattc
    40261 tgtatgagca gaccattttt ccccatcaaa tatttccgaa cgataagtga cttctagcgt
    40321 atattctcct tttgaaggtg ctgaaaaaat agcggtatga ttagaaaatt gagcacttga
    40381 ctgtgtttca acgatttgga tcttttctgg gaaataacgc atatcttcaa agacaggcgt
    40441 tccttgattt ggtgtgaaag ttgacacaaa aactgtaaaa ggcttcagtt caatgatatt
    40501 tccttctgca ttctccgcca caccatttgc ttcttgtata ataatcggat tattttgttc
    40561 atttggtttt gtctgatttg gttcttgtac gattgcatac tctggatatt ccgaagatgg
    40621 cgaggtttct ccgtcaaaaa tagcacctac agataatgga agaccatcca ctctttcctt
    40681 ttctgtttga cgattccccg gtttaatctg catcagtcca tgaacatgga tacttccatt
    40741 ttcatagcgc gtaacaggct gctgaccttc tttcgaacat gtatttagag actcgatcca
    40801 atcttttgat acggtatgtc caagagtatt ttctgattgt ttctctcgtt cattccaata
    40861 gtagttcaac gagtggtaga tttgatcttc gttttgattc aatgggcgga tctgctctct
    40921 catctcaaga ttctctgttc ggaaagataa gataccagaa gcatggtagt ctgtgtttcc
    40981 tgctgaagag gtataaagag ccacattata tgaaccgtta ttaaaacttg tactgctatt
    41041 gacgataata tctgttccgc tattggaatc gattcctttc gcaagatttt cgaaagacaa
    41101 actattgatc aattcatgag ggcccgttaa aaaagaaccg cccattttga atccattacc
    41161 gttaccttct ccctcaattc ccggtaccca gccgtttcga taagcaactg agtttttgat
    41221 gattactttt ccgatcgaac ctgtttcatt tttagcaaaa aggtcccaac cgtcatctgc
    41281 attatgatac gcgatacaac cgtcaaatac atttccttct cctattgtca gtttggccgc
    41341 aaatccatcg gcatcttcaa atcctggatc ggcattttca aaagatgtac agttcttgac
    41401 taagttatgc gcgggccatg cttcgaaagg atcatttgag ctaccgctga tttggattcc
    41461 tgtatttcca ttccgataag catgaatctc ttcgatcaaa ttatgatttc cagaaatctg
    41521 taatcctttt tgcatagctg cactatttgt aatgtcaaac cctcgtaaac cccagtagtg
    41581 actgaacagt gtcatcccat ttccagttcc tttaaaatca agtacaggac gcttgttttc
    41641 tggatttttc tctgcaatca acttaatcgg gttttctctt gtcccgttaa cgcctttggg
    41701 aatcgtcaat cctctttcga aggaataagt tccaggcgcc atgacgattg tctgcccagc
    41761 atatgcgtat ctcaatgctt gtgtcagaga taatggattt tgtctgcttc cgtttcctgc
    41821 atctgaccct tctggtgtta cataaactgt cgaatattta ggtttacggt agtccactgt
    41881 atgaagaatc tcttttgttt cataactagt catctctacg tattcttctg gcggatagtt
    41941 tttatctggc gtaaaactga aagtaaattc gttcgttcct tccatcagtt ttgtctgata
    42001 atcaaattcc cgattcgcag tgatagccaa gtcttttgcg ttcttaagca cctctcctgt
    42061 tgctttattt ttaattgtca ataatccgtc agcatttgct ctaaaggaca tagtatgatc
    42121 ttggtttcct gaatgattac tagaggtcac agtgtaaatc ggatcaatca agcgagtagg
    42181 tctttcttgc ccaggaggat ctgtcgcagg atctgagtaa gcaacttcga ttccttctac
    42241 cttgatcgtc atattccttg ctgcagcaaa tcctgcataa ataaccgatt catctgaagc
    42301 gtataatttt tcccagtcat acatgatgtc agaagccatt tcttctcctg tttcaggatc
    42361 gtaataatat gcctctaaac cagtattcgt ttttttcatc tctacgtcca gtttagtaat
    42421 cgagttcgtg gccggaaaca gattcccatg accgtttccg aatatattat aagaacctgt
    42481 ttctttttcc aagaaccctg ctgaagtctc taaaggtgtt gtttccactg agacactccc
    42541 aggagctggc gcagcttgcg gatcttcaga tgatattcct gtgattgccc gtgtccccaa
    42601 tccaagtcgc atcgtatatt tgctgccgct cgtgttgacc acttcttgtc tatccgagtc
    42661 ccagacatat tcgatccgac tgcctagtat ggcaaatgaa tttgaataaa atgcctgccc
    42721 aaacaaatga tcttttggta ctgcgtctct taccattaaa gcaaatcctt cttgggcatt
    42781 cgtataggtg caagattcta tttcgatcgt cgcccgcatc ctaaagttga tgtctttggg
    42841 gattgcttga taataatagg tcattccatc tgatccgctt gactggaatt ttccgccgtt
    42901 attcgtggaa gagagccgca cgccgtcttc taatggttca atggcatacc tactagcact
    42961 tgtgctttct ccgaaaacaa cccctttcca ctcttcattt gcttcttcag attgcttttt
    43021 tgtcttttca ttttctgatt ctttcatcat aggatcattt ccttcttccg tatccatatc
    43081 ttcactagtt cttggtactt cctccattgt tgacatccct tcaatgttca cgtgtgcatt
    43141 ttcttcgttc acagactgtt gttcgttagc agcaacttca acgacagaaa ttaaaaccgg
    43201 ggtactgagc ataaggagat tcatcattag cgcactgtat tttatacgtt tttttaacaa
    43261 gtgtattcct cccgcaacaa attagaaaac gtttacttaa agtattacct aatttatttt
    43321 tactgtcaat aaaaaacaaa attataataa gtgtatttta taaaaagaaa aaacataact
    43381 taagttgttg ataacaaaga gatttattaa cgtaaaaaga ataagatttt tttaaaataa
    43441 cgtataaaga agagcataaa acaaagtcgt ttgttttatg ctcttctttt attattttgt
    43501 actttttatt ttatcaaatc actttgtttt tttataaaat ttctgcgcct agtgtggatt
    43561 caaaatgtct caatgcccat tcatgtccaa cgggatcgaa acttgccacg gcatctttga
    43621 aaatatggag tttgtatcct agattatacg catcgactgc tgtatgcaac acacagatat
    43681 ctgtacatac gccggtcaaa taaatatctg tgatctggcg ttctcgtaaa cggatgtcta
    43741 gatctgttcc actaaaagcg gaataatgcc gtttgtctat ccaataaaca ttttcctctt
    43801 gctcatagtc ttggtataaa ctttttaaag agccgtacaa ttcccgtcca cccgttccta
    43861 tcacattatg cggaggaaat aagcggttct ccggatgaaa ggaatctttt ggatcatgcg
    43921 catcaatggc aaaaacgaca aaatcctttt gatcaataaa cttctttgta tgagcagtca
    43981 gctttttttc aattacttgt cctgctgtcc cagtagtcag ctttccatcc tctgcaacaa
    44041 aatcatatgt gtagtcaatc gagatcaatg cgttcatctt agtcctcctt atacgagatg
    44101 tttgacaaat tcgatcacca tttctgctga tcgtttgcct gcgtcttcga taaattcgtc
    44161 aaagctttgt gtcgccgagt gatctgctgt gtcgctcatt gcacgtacga tcaaaaatgg
    44221 gatattgaac tgacgagctg tttgtccaac agcggctcct tccatttcgc aagctaatgc
    44281 ttcagggaaa ttcgttaaga tttctttgat tttatctggc gagtcgacaa atgtatcacc
    44341 tgtaacgatc aatccttctt ttgcgttcaa attcgttgct tttgctgctt taaccatttc
    44401 actgcgcaaa tatgtgcttg cttcataata tagaggcatt cctggtaatt gtcctggttt
    44461 gtagccaaat cctgttgcat ctgcatcaaa ataagctact ttgtctgata taacgatgtc
    44521 acctacttgt aagccttcac cgattccgcc agctgaacct gtattgatca ccatgttcac
    44581 gccgtattgt tggatcaaca gacttgtggt aatagatgct aagacttttc ctataccgga
    44641 acgtacgacg atcacttcgt ggttacctaa tgaacctgaa ataaataaag cgcctgcgcg
    44701 ttcccatgat aatggttcgc ttaggttctc tctcaaaatt tttacttctt cttccattgc
    44761 gccgataata ccgattttca tctttttaat tccttctttc tatataaatg cgattgctaa
    44821 aaaaaccaca cataacatta ggataacaat aataagagat ttcatcaaaa aagagttcca
    44881 tttggtcgtc ttttcccgtt cgctgatcct tgttttcgtg attggtttat tctttttgct
    44941 ttctttacga taaaagctgg caatcttttt ttcttcttgc tgataagctg tttctgcttt
    45001 tcgctgtttt tttaatgact cgcttgcttg tgcttgttgt cgcttgcgaa gttcgcttcg
    45061 cgtaataagc ggtcctttgg ccataagccg atccctctac tttcctttgg tcaatagttc
    45121 ccagtattga atcgcataaa tcgtctttgc atcacaaatc aactgatctt tcatcgcttg
    45181 ttgcgcctct tcaagagtta gatgatacaa ctccagtact tcgtcttcat cttgtgctaa
    45241 aggattctcg accttctcta ccccttgtgc atgataaata tgaaggactt cattagcaaa
    45301 acctggtgaa agatacatcg aagtaagatg gctcagcgac ttcgcacgat agccagtttc
    45361 ttcttctaat tctctagctg ctgtcatttc gggattttgt ccttctcctg gatcgatttt
    45421 tccagctgga atctccaaaa tcactttttc taaaggtttt cgaaattgct tgacaagaag
    45481 cagacgatct tgttcgtcaa aagcaatgat cccaacaccg ccaggatgaa ataccagttc
    45541 tctcttcgaa gttcctccat ctggcaaacg aacttcgtct acagcaacat caataatttt
    45601 tccgctatag atttctttgc gactgattgt tttttcttca aattgctcat tgttcagcat
    45661 atcttctcct gctttctttg taatcataac tgcttttttt catttttcaa tttttctcaa
    45721 aaactcctta ttagtttacc atagataaac cttagatttt ctctaaatat agaaaatcct
    45781 tctttagtcc gatactcttt ctagtagtcc gtatgctaaa ataagtatgt aatcgaataa
    45841 cgaaaagaat tcaatactca acgataaatg acatggaggg tttattatga taaaacgaaa
    45901 ttggccgtgg cttctagcat tggtcttgct atttctcttt ggtttttctt ttgttctagg
    45961 acttttattg ataggtgtag ttttagtttt gtggggactc tttggttcgc gcaggaaaaa
    46021 gggaaaacaa gaagaaattc ctgcactgac taacgaactt gaaactcact atgaaaaaag
    46081 cggtatgaca gcgaatgaaa tttcattttt tcgacaaaca atgaatcaaa caaaaaatga
    46141 gatcaatcaa ttgcaaatga atatgcagca gacagccaaa cttaaagcaa tcgatctccg
    46201 ccatgatcca gtcaaagcag caaaagcttt attcaaagaa ttggtgaaag aaccaaaccg
    46261 actgcatgaa gcaagtcagt ttctttatac gcatctgccg aatctagttg atttgacaaa
    46321 taagtataat gagatcaatg accatgagat caaaaacaaa cagacctatg aaaaactaga
    46381 agaaagcgcg cagatcatcg accagctgtc agctttaatc gcacaagatt atcaaaaatt
    46441 cgttgctgag gatctagatg atatcgacgt agagatatct gttgcgaaac agagcttaaa
    46501 gcgtgataat aaatatgaac cagaacaaaa ggattaactc ttttgttcat aaaagaagac
    46561 tcggaacatt cagatgatgt ctggctgttt cgagtacttt ttctaaagta gagacattca
    46621 tgtaagaatc gagaacagat tcaacaagga ggaatttttt atggatcata aaccgactga
    46681 aacaaaagat gttacaccag ttaacgatac acttgaagat ttattgaaca acccgttttc
    46741 aactccaaca gatacgctga ccacttcaca acaagcggag attgatcagc tccaagagca
    46801 acagacagct gctcgtttaa ttgacaaact accggcggaa cgccaagaac aagctaaaca
    46861 gctagcagca aaaatcgatg ctaatgatgc acagtctgtc atcagctacg gatcggctgc
    46921 ccaagcaaaa ttaagtgaat tctcacaatc gatgttgaat catgtgcaag cacaagatat
    46981 tggtcctgta ggagattcct taactgaact gatgtatcgt ctccaagaag ccaatcctga
    47041 cgaactgcgt gccggagaag ggaacatctt ccagcgtgtc ttcgggaagg tcaaacaatc
    47101 gatctatgaa gtgacagcaa aatatcaaaa gattggtgca caaattgaca agatttcagt
    47161 gaaattagat aaagaaaaag acggtctgct aaaagataat ctgatgttag aacagcttta
    47221 ccagaaaaac aaagactact ttgatgcact gaatatttat atcgctgctg gagaattgaa
    47281 aatggaagaa cttcaaacaa cgatcattcc agaagcgatg aaaagagcag aagaaactgg
    47341 cgatcagatg gatgttcaga ttgccaatga ttacacgcaa ttcctagatc gtctggataa
    47401 acgtacgcat gatcttcgct tagctagaca gatcacgatc cagcaagcac cacaaatccg
    47461 tttgatccaa aacacaaatc aggccttggc tgaaaagatc caagcatcta tcgctacagc
    47521 cattccgctg tggaaaaacc aagtcgtgat cgcattgacc ttgcttcgtc aaaaagatgc
    47581 agtaactgct caacgccaag tctctgaaac aacaaacgac ttattgaaga aaaattcaga
    47641 aatgctgaaa atctcagcca tcgaaacagc gaaagaaaat gaacgtggaa tcgtggatat
    47701 cgagaccctt caaactactc aaaatgattt gatcgaaaca atccaagaga cattgcgtat
    47761 ccaaaaagaa ggaaaagaaa aacgtcgtca tgcagaagta gagcttggac acatggaaga
    47821 agatctgaaa caaaaactgt tggatttaac ccaatagatc acctttcgct tgttactaaa
    47881 acaaacgccc aacaacagtt tattacaact gttgttgggc gtttttctta tctttcttct
    47941 aacttctcca ttggagtcta tttctcattc atcttgctgt gtccatagcc atagccaaaa
    48001 taaatgatca gtccaataac cattacgata ccgaacacga tccatgtcac agtttgcaga
    48061 cgaagcatca atacaataca agtcaagatg gaaatgattg gcaatagcgg aacgaatggc
    48121 actttgaatt ctccagcttt tggtttgcca aacatttttc tcaactttag taagcctaga
    48181 ctaacaagca tcaaataggc gagcgccatg atattcgtta gttccgctaa tacattcaat
    48241 gggaaaaatc cggcaaagaa tacagctgcc acaccagcgg cataagtcgc ttttttcggt
    48301 gtacgatgct tttgatcgat ttctgtcata aacttaggaa gtaagccatc cttgctgaca
    48361 gcaaacagta aacgagcaag tgaatacatc atcgagattg ttaccgtcag tagcgttaaa
    48421 atggccccta cagcgatcac cgcgcccact gttccatgtc ctacatacct cattgcaaaa
    48481 gccactgggt cattgactcc tagttcagta tacggaacga ttcctgtcaa gatcagcgtc
    48541 acgatgatgt aaaggacagt agcaatcagt atcgaaccaa tgattcctct tggcacatct
    48601 ttttgcgggt ttttgacttc ctcggctgcc attgcaacgg catcaaatcc caagaaagca
    48661 aaaaacacaa gagctgcacc atctagcaca ccggaaaaac caaaaggcat gaatggctgc
    48721 caattatcag gtttaacgaa aaatattcct acaatgataa acaacgcgat gataccaaat
    48781 ttgacatata ccatggcatt attcaaacgt aatgctttct tggcttcaag cgacacgatg
    48841 taagtgacga atatcactac gagcaccgca atcaagtcaa tgtatgtacc attttccgga
    48901 ttgtacccgc cagttaatgc ttgtggaagt tcggccccta aacttttcaa aaaaccttgc
    48961 atatagccag accatccgga agcaacagag gaaaccgcta gtaaaaattc cccgatcaac
    49021 aaccaccctg tcagccaggc agcaaattca ccaaatacaa catacagata ggcatatggc
    49081 ccaccaatca ctggcactcg cgaagcaaat tctgcgaaac ttagtccaga caaaatgaca
    49141 acgattgcag ctaagacaaa tgaaaatgac agtgctggac cagcattttg attggccgca
    49201 acccctgtca ccacaaatat tcccgtaccg atgatcgcac caattccaag catgatcaaa
    49261 tcagacgttt ttagttcttt tttcatctca ctcgtatgat tgagattgat ctctttctta
    49321 cgaaacaaat ccattgaagt tcctccccat tttaggttgg aaaacagcga ttaaactgtt
    49381 ttcatatacc ctaaaaggat accacctaaa atgactaaaa ggcaaccaac aataacataa
    49441 atgagctctt ttttcgtttt tctttcgcca aggatgaaaa tcccacctaa agtagagata
    49501 atgatcccca tttgtgaaag tgagaagcca acagctaaac caagtgattt gactgttaga
    49561 agcatgcaga tgtttcctaa gccccataat aatccacaga tcatgttttt ccacacaaac
    49621 tgatcgactt taactttacg gaaagcaaag aagcttgcgc ctaagatcat tccgatactt
    49681 tgaggtaaga taattgacat cgcatccaaa ttcgcccagt tgacgatgat ggtatataca
    49741 ccataaccaa tcgtagagaa gatcaatgct ctaaaaccct taccaaaatc aagcatttta
    49801 ttatctgtat ctatttttcc ttcgtcatct tgtcgggcag tcaaatacgc accgcttaca
    49861 agaagagcta aagcaataat accgtataca taatctttcg tttgtgtcca ttcatggaag
    49921 aaaacggctc ccgcaatcgt attcaaaatt aattgaaaac cagtagacaa tggtaaccct
    49981 acagaaacac ccatgtactt cattccatgg aactgtccat tttgtccaac actccaagct
    50041 aagccggata aaaatccgat caagaaaatc caaggggtga ttacaggact aacaacgaaa
    50101 aagacaacta aagaaaacag aaatgcaccg atcgtcattc ctagtgtttg ttgattggca
    50161 tcgccaccaa ttttaccact tactaaacca atactacccc atgccaacat agggactaat
    50221 gctattaaaa tttccataac caatctcctt ttatttcaca tgataagaaa cttatcagcg
    50281 aaaacgttaa caacacaagc actttttttc gtttctaacg attttctaac gtttttcatt
    50341 ataaaaattt aagattggga aaaataaagt cattgttgtc ccttttcctt cagttgattc
    50401 agccgtcaaa tggataccta atttttcggc cagatttttt gctaaataaa gtcctaatcc
    50461 tgttgaatgt gttttgctaa gtcgaccatt tctcccagta aatcccttat caaagatccg
    50521 tttcaagtct tccgctggga taccgatccc tgaatcttta actgaaaggc tgactccttg
    50581 tgcttccttt tctatgctca caatgatgtt tccgtgatcc ggcgtatatt tgatggcatt
    50641 actaagcaat tggttgaaga taaaagcgat ccatttagca tcggtcaaaa cagtatgatc
    50701 ctcaccaaca atctcgtagc gaatattttt ttggataaaa taatttgcct gactgcgtat
    50761 cacaggctga atgattcctt ttagcctata ttcttggatg aggtagtccc gcgaaaaact
    50821 gtctagtctt gcataataca aaacttgttc tacgtattca tcgatttttg ataattcatt
    50881 ttctagtaat gtatactttt gatcgtcaat atcgaactcg atcgaacgaa ctagcaattt
    50941 agaagcggaa agtggcactt tgatttcatg gacccatgag tcaatataat ctttttggtc
    51001 ttgttgatta ctgattgctg attgcattac ttcttggtgt tcacggatca gctgattgat
    51061 atattcttct accagttttt cttcttctgt tcgtccaccg ctcaaatagt tttgcaaagg
    51121 ggaagttttt tgtatgtcgg ctaattttcc ccaccatctt ctcttgctca agtaaccacc
    51181 cagcagataa aaaatcagaa agacgccctc aatcaaagct aaataagcaa ttgtgctcaa
    51241 atcaactttg atgtttggcg ccagccacat cacaaagatc gtcaatgcaa taaaaaacag
    51301 ccatcccaag atcaatgtcc actgatcttt caaatattta aaaaaattca tcttaaccgc
    51361 tcatcctttc agggaacgat atatccctgt cctacttttg tttcgatata tccttggata
    51421 cctgcctgtt cgatttttcg gcgtaaccga ttgatgttga ctgtcaatgt attgtcatct
    51481 acaaatcgtt cgtcatccca cagtgctcgc agcaattttt cccgacttaa gatctttcca
    51541 ttgtgcttca tcaaaataaa taatagacga tattcatttt tgctcaaatc aatgatctct
    51601 ccgttgattt ccatacttcc gttgtcaaca ttcaacgtaa tgccattgtg gctcatcatt
    51661 tcactagata attctgtgta gttgtaagaa cggcgaagta atgcattgat ttttgcaatc
    51721 agtacatcga tttggaaagg ttttgtcaca aaatcatctg cccccatgtt catagccatg
    51781 atcatatcca tattcgtatt cctgctggag ataaaaatga tcggtacttt cgatacttca
    51841 cgtatttttt gacaccaata atagccatcc aaaacgggaa gattaatatc tagtaataca
    51901 agctgtggtt cttctctttc aaagtctgag aacacttgat tgaaatcggt cgttccaaag
    51961 gtttcaaatt gccatttctc aagttcctcc atgatcaatt gtcgaatgat ctcttcgtct
    52021 tcgactacca tgatttttgc cataaaaaat ccctccatct ttcttcttgc tactacaata
    52081 tcaaagaagc ccttgtgaaa caagttggct tacctggaaa atgtcatttt agcaaacgtt
    52141 aaaaaaaact ggaaatatgc gatttaatcg cttttgtctt ttcaatacag cttaaattta
    52201 ttatgttatt cttaacaatt ggtctatgat ctgttatttt tccttagttg tttttgtctt
    52261 ttaaatttcc aataacacca ataaccgaaa agcgttagca ctagcaatat acctagaagg
    52321 agtataagta atcgataaag atggtatttt tttgtctgtt ctatctttga agagacttct
    52381 tctgtaaagg gaactcgcct tcctgtcact agtaatcggt gagtgttcac ggtgtaaggt
    52441 gtacaagtga taagtgtgac tagatcctgc ttttctctga ttgctaatgt atttgttttt
    52501 gttggaagga caacaatttt ctcaacgact tcataagcga gcatccgacc atacacttca
    52561 agatagaatc ggtcatcttg ctccatttct tcaagatccg taaagagttt tttctcagca
    52621 ataccgctat gggcggtaat cacggaatgt gtactctctc ctccagttgg aaaagaggtg
    52681 ccttgcagga ctgtcgctcc tctatctaac aaaagatcat tcgtttcatc aaataaaggc
    52741 aagctaacat tgattttcgg aatatagatt gctccgatca tatgttgttc gtagtattct
    52801 tttcctggat ttcggacatt tctaaccgct tgctcaaaag gatctttgac ttgtcccatt
    52861 cctgggatta ctgatgtatg agcaagcgtc tgatttttct tttcatgcac tgctaattgt
    52921 tgctcatgtt tttcttcttt atcgcgttca agctgctttt gataattctc gatccttctt
    52981 tgatccaaat aattgctgag agcatctgct aaaaatggat atgtaaaaac tgcagctccg
    53041 gcaagaaaca tcactgccat aaataattgt aataaaagac tgatttgggt ttgaggtcta
    53101 ttacctgttc tctttttcat tttcttcacc ttcttattta aaaaaactgc agcaatcggt
    53161 tttataaagg ttgctgcagc ttatttttgt tgcttatact tcagacttca ttttaaattt
    53221 acggtaccag ctgtacgctc caatcatcaa acttattccg attagtaaga atgccaagag
    53281 cccgttccca ccagtagcag gaagtgaccc gcgtttcata ttcggtactc tttctggccc
    53341 tggattttct actcctacga tctgaatttc ttcattatag cttccataag agatgataaa
    53401 ttcagtaaag gctgcctcac ctgttggaag tacataa
//
LOCUS       DAXQKX010000015        53250 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.015, whole genome shotgun sequence.
ACCESSION   DAXQKX010000015 DAXQKX010000000
VERSION     DAXQKX010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 53250)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53250)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53250
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.015"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(61..2424)
                     /locus_tag="ACF3MF_000943"
     CDS             complement(61..2424)
                     /locus_tag="ACF3MF_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase"
                     /protein_id="HFE3926960.1"
                     /translation="MDYSSKEYFDKMTAWWRAANYLSVGQLYLKDNPLLRRTLKPEDV
                     KKHPIGHWGTIPGQNFIYVHLNRVINKYDLNMFYIEGPGHGGQVMVSNAYLDGSYTEI
                     YPEVTEDETGMQKLFKRFSFPGGIASHAAPETPGSIHEGGELGYSLSHAVGAVLDNPE
                     VISAVVIGDGEAETGPLAGSWFSNVFINPVIDGAVLPILHLNGAKIANPTILARKSDG
                     ELANYFNGLGWEPFFIEGNDPEKLNPVMAEKMDQAIEKIKSIQKEARLKTATDVVMPK
                     WPVLIVRTPKGWTGPKEWDGEPIEGTFRAHQVPIPVDQEHMDHADALLRWLKSYEPEK
                     LFDAQGRILEEIREIAPTGDQRMAKNPITNGGIDPRPLIMPDWKKYTLQFEKPGSVKA
                     EDMTELGKFVREIIEKNPENFRIFGPDETKSNRLNQVFKTTNRQWMEKIEPENDEWLS
                     PSGRVIDSQLSEHQDEGFLEGYVLTGRHGFFASYESFLRVVDSMLTQHFKWIRKSHDL
                     SWRKDYPSLNLIASSTVFQQDHNGYSHQDPGILTHLAEKKAEFIREYLPADANTLLAV
                     MDKAFRSSEKINLIISSKHPRAQFYSAEEAAVLVNEGLKIIDWASTAKEEEPELVIAA
                     AGTESNLEALAAVTLLLEEFPKLKIRFINVVDLLKLRHPSQDPRGLSDEEFDQYFTKD
                     KPILFAFHGYETLVRTIFFDRHNHHLMIHGYKENGDITTPFDMRVVNELDRYHLAKDA
                     ALKIKGSQAEDFAEKMDQKLQEHQNYIRENGIDLPEVLDWKWKNLDQ"
     gene            2589..3093
                     /locus_tag="ACF3MF_000944"
                     /pseudo
     CDS             2589..3093
                     /locus_tag="ACF3MF_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035543.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(3201..3548)
                     /gene="rbfA"
                     /locus_tag="ACF3MF_000945"
     CDS             complement(3201..3548)
                     /gene="rbfA"
                     /locus_tag="ACF3MF_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HFE3926961.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKKAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(3575..5881)
                     /gene="infB"
                     /locus_tag="ACF3MF_000946"
     CDS             complement(3575..5881)
                     /gene="infB"
                     /locus_tag="ACF3MF_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HFE3926962.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSSDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(5894..6205)
                     /locus_tag="ACF3MF_000947"
     CDS             complement(5894..6205)
                     /locus_tag="ACF3MF_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HFE3926963.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(6202..6495)
                     /locus_tag="ACF3MF_000948"
     CDS             complement(6202..6495)
                     /locus_tag="ACF3MF_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HFE3926964.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(6517..7692)
                     /gene="nusA"
                     /locus_tag="ACF3MF_000949"
     CDS             complement(6517..7692)
                     /gene="nusA"
                     /locus_tag="ACF3MF_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HFE3926965.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(7716..8189)
                     /gene="rimP"
                     /locus_tag="ACF3MF_000950"
     CDS             complement(7716..8189)
                     /gene="rimP"
                     /locus_tag="ACF3MF_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HFE3926966.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(8333..12685)
                     /locus_tag="ACF3MF_000951"
     CDS             complement(8333..12685)
                     /locus_tag="ACF3MF_000951"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HFE3926967.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIQ
                     LGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSFIV
                     KKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYAPE
                     GEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGKKA
                     GVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAVKM
                     YKGNVIESFDEFIDPGHPLSRTTVDLTGITDEMVRGSKSEEEVLRMFLEFSKDTILVA
                     HNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSLEQ
                     HHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILAKN
                     QAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKGVE
                     EARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVATGN
                     VHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEIVV
                     ENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRLEK
                     ELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAPHY
                     YCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPDID
                     LNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSAEV
                     DRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHSIH
                     DNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIYSK
                     TGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDATLA
                     EVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVPDW
                     YIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMCKG
                     KDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFVIE
                     GDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGVLK
                     DLPDENQLSLFDML"
     gene            complement(12897..14606)
                     /locus_tag="ACF3MF_000952"
     CDS             complement(12897..14606)
                     /locus_tag="ACF3MF_000952"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HFE3926968.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPKRDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            complement(14674..15942)
                     /gene="rseP"
                     /locus_tag="ACF3MF_000953"
     CDS             complement(14674..15942)
                     /gene="rseP"
                     /locus_tag="ACF3MF_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HFE3926969.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(16103..16903)
                     /locus_tag="ACF3MF_000954"
     CDS             complement(16103..16903)
                     /locus_tag="ACF3MF_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HFE3926970.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(16900..17712)
                     /locus_tag="ACF3MF_000955"
     CDS             complement(16900..17712)
                     /locus_tag="ACF3MF_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HFE3926971.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(17907..18464)
                     /gene="frr"
                     /locus_tag="ACF3MF_000956"
     CDS             complement(17907..18464)
                     /gene="frr"
                     /locus_tag="ACF3MF_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HFE3926972.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(18467..19189)
                     /gene="pyrH"
                     /locus_tag="ACF3MF_000957"
     CDS             complement(18467..19189)
                     /gene="pyrH"
                     /locus_tag="ACF3MF_000957"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HFE3926973.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(19325..20206)
                     /gene="tsf"
                     /locus_tag="ACF3MF_000958"
     CDS             complement(19325..20206)
                     /gene="tsf"
                     /locus_tag="ACF3MF_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HFE3926974.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(20305..21087)
                     /gene="rpsB"
                     /locus_tag="ACF3MF_000959"
     CDS             complement(20305..21087)
                     /gene="rpsB"
                     /locus_tag="ACF3MF_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HFE3926975.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            21446..21925
                     /locus_tag="ACF3MF_000960"
     CDS             21446..21925
                     /locus_tag="ACF3MF_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFE3926976.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            22142..23233
                     /gene="phnW"
                     /locus_tag="ACF3MF_000961"
     CDS             22142..23233
                     /gene="phnW"
                     /locus_tag="ACF3MF_000961"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047304 - 2-aminoethylphosphonate-pyruvate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HFE3926977.1"
                     /translation="MYKLLTPGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSGSFGVESVLSSVIRPEDTVLICSNGAYGQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQEKDLL
                     FIVDAMSSFGGIPIRVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            23226..24011
                     /gene="phnX"
                     /locus_tag="ACF3MF_000962"
     CDS             23226..24011
                     /gene="phnX"
                     /locus_tag="ACF3MF_000962"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050194 - phosphonoacetaldehyde hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HFE3926978.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIREP
                     MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEHYLFKDLVKHSTLKP
                     DTLETIERLRNAGINIGSTTGFTAPMMTIVAETAKKEGYSPDFMATSEDVEGYGRPFP
                     YMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEGSSLMGISYDEYQKL
                     EMGKKDRLKQSVALRFQQAGADICVNNLKELTEYILYADKNPE"
     gene            complement(24357..26048)
                     /gene="argS"
                     /locus_tag="ACF3MF_000963"
     CDS             complement(24357..26048)
                     /gene="argS"
                     /locus_tag="ACF3MF_000963"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HFE3926979.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDEEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMRHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(26470..27417)
                     /gene="arcC"
                     /locus_tag="ACF3MF_000964"
     CDS             complement(26470..27417)
                     /gene="arcC"
                     /locus_tag="ACF3MF_000964"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HFE3926980.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(27532..28551)
                     /gene="argF"
                     /locus_tag="ACF3MF_000965"
     CDS             complement(27532..28551)
                     /gene="argF"
                     /locus_tag="ACF3MF_000965"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HFE3926981.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(28642..29871)
                     /gene="arcA"
                     /locus_tag="ACF3MF_000966"
     CDS             complement(28642..29871)
                     /gene="arcA"
                     /locus_tag="ACF3MF_000966"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HFE3926982.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            30332..31033
                     /locus_tag="ACF3MF_000967"
     CDS             30332..31033
                     /locus_tag="ACF3MF_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFE3926983.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(31605..32621)
                     /gene="tsaD"
                     /locus_tag="ACF3MF_000968"
     CDS             complement(31605..32621)
                     /gene="tsaD"
                     /locus_tag="ACF3MF_000968"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HFE3926984.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIVAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(32618..33082)
                     /gene="rimI"
                     /locus_tag="ACF3MF_000969"
     CDS             complement(32618..33082)
                     /gene="rimI"
                     /locus_tag="ACF3MF_000969"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFE3926985.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLVEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(33089..33631)
                     /gene="rimI"
                     /locus_tag="ACF3MF_000970"
     CDS             complement(33089..33631)
                     /gene="rimI"
                     /locus_tag="ACF3MF_000970"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFE3926986.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTIEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(33615..34337)
                     /gene="tsaB"
                     /locus_tag="ACF3MF_000971"
     CDS             complement(33615..34337)
                     /gene="tsaB"
                     /locus_tag="ACF3MF_000971"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HFE3926987.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDKIIVPMFDARRKNVYAGAYRWKENRLEIVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFYEIKEILPSAMINTVPAWDIPSGVTVAQLGALAEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(34528..35508)
                     /locus_tag="ACF3MF_000972"
     CDS             complement(34528..35508)
                     /locus_tag="ACF3MF_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFE3926988.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPTDGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(35532..37016)
                     /gene="galT"
                     /locus_tag="ACF3MF_000973"
     CDS             complement(35532..37016)
                     /gene="galT"
                     /locus_tag="ACF3MF_000973"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HFE3926989.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLADYPQVIAGVVKWPMSVIRLQSAEKKLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(37028..38017)
                     /gene="galE"
                     /locus_tag="ACF3MF_000974"
     CDS             complement(37028..38017)
                     /gene="galE"
                     /locus_tag="ACF3MF_000974"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HFE3926990.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREVLGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            38266..38433
                     /locus_tag="ACF3MF_000975"
     CDS             38266..38433
                     /locus_tag="ACF3MF_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HFE3926991.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(38495..40306)
                     /locus_tag="ACF3MF_000976"
     CDS             complement(38495..40306)
                     /locus_tag="ACF3MF_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HFE3926992.1"
                     /translation="MKIGIIGAGPRGLSIAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNDLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSREGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGSMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLEIPLTYQDESFAEASRAFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPVIRTKELAALIDAGIFHLFEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(40303..40668)
                     /locus_tag="ACF3MF_000977"
     CDS             complement(40303..40668)
                     /locus_tag="ACF3MF_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HFE3926993.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(40831..41226)
                     /locus_tag="ACF3MF_000978"
     CDS             complement(40831..41226)
                     /locus_tag="ACF3MF_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFE3926994.1"
                     /translation="MVLWVINIILLLIVLAIIFWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(41244..42206)
                     /locus_tag="ACF3MF_000979"
     CDS             complement(41244..42206)
                     /locus_tag="ACF3MF_000979"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HFE3926995.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRYLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACANLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(42206..42418)
                     /locus_tag="ACF3MF_000980"
     CDS             complement(42206..42418)
                     /locus_tag="ACF3MF_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HFE3926996.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(42439..43137)
                     /locus_tag="ACF3MF_000981"
     CDS             complement(42439..43137)
                     /locus_tag="ACF3MF_000981"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HFE3926997.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(43157..43699)
                     /locus_tag="ACF3MF_000982"
     CDS             complement(43157..43699)
                     /locus_tag="ACF3MF_000982"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HFE3926998.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(43831..44835)
                     /locus_tag="ACF3MF_000983"
     CDS             complement(43831..44835)
                     /locus_tag="ACF3MF_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFE3926999.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIGLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(44832..45821)
                     /locus_tag="ACF3MF_000984"
     CDS             complement(44832..45821)
                     /locus_tag="ACF3MF_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFE3927000.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(45818..46624)
                     /locus_tag="ACF3MF_000985"
     CDS             complement(45818..46624)
                     /locus_tag="ACF3MF_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3927001.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKITLLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            46790..47746
                     /locus_tag="ACF3MF_000986"
     CDS             46790..47746
                     /locus_tag="ACF3MF_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFE3927002.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(47823..48341)
                     /locus_tag="ACF3MF_000987"
     CDS             complement(47823..48341)
                     /locus_tag="ACF3MF_000987"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0005542 - folic acid binding [Evidence
                     IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HFE3927003.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(48429..48578)
                     /gene="rpmG"
                     /locus_tag="ACF3MF_000988"
     CDS             complement(48429..48578)
                     /gene="rpmG"
                     /locus_tag="ACF3MF_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFE3927004.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            48806..49252
                     /locus_tag="ACF3MF_000989"
     CDS             48806..49252
                     /locus_tag="ACF3MF_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HFE3927005.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(49447..51342)
                     /gene="asnB"
                     /locus_tag="ACF3MF_000990"
     CDS             complement(49447..51342)
                     /gene="asnB"
                     /locus_tag="ACF3MF_000990"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HFE3927006.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKLDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(51667..52641)
                     /gene="bsh"
                     /locus_tag="ACF3MF_000991"
     CDS             complement(51667..52641)
                     /gene="bsh"
                     /locus_tag="ACF3MF_000991"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HFE3927007.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGEGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNINKEDLDRHELVSYPVIKEQQINYVN"
BASE COUNT        15059 a        11313 c         9303 g        17575 t
ORIGIN      
        1 cttaatttga caaataatac aatgtaaaaa attctgtttt gcgggatcga ttttatcatt
       61 ttattggtca agatttttcc atttccaatc caatacttct ggcagatcaa taccattttc
      121 acgaatatag ttttgatgtt cttgtaattt ctgatccatt ttttccgcaa aatcttctgc
      181 ttgacttcct ttgattttta aagctgcgtc ttttgccaaa tgataacgat caagttcatt
      241 tactacacgc atgtcaaatg gtgtcgtgat atctccattt tctttgtagc catgaatcat
      301 taaatgatgg ttatgacgat caaagaaaat cgtgcggacc aatgtttcat aaccgtggaa
      361 agcaaataag atcggtttgt cttttgtaaa atattgatca aattcttcat cgctcaaccc
      421 acgcggatct tgacttggat gacgtaattt caataaatct acgacattga tgaaccgaat
      481 ttttagtttt gggaattctt ccagcagcaa agttacagct gctaatgctt ctaagttaga
      541 ttccgttcct gcagcagcaa tgaccaattc aggttcctcc tcttttgctg tcgaagccca
      601 atcaatgatt ttcaagcctt cattcactaa gacggctgct tcttctgctg agtaaaattg
      661 agcacgcgga tgtttggaag agatgatcaa attgattttt tctgacgagc ggaatgcttt
      721 atccatgact gcgagcaatg tatttgcatc cgcaggcaga tattcacgga tgaactccgc
      781 cttcttttct gccaaatgtg tcaatattcc tggatcttgg tggctatatc cattgtgatc
      841 ttgctggaag actgttgagc ttgcaatgag attcagcgaa ggataatctt ttcgccaaga
      901 aaggtcatgt gatttccgta tccatttgaa gtgctgagtc aacatagagt caaccactcg
      961 caagaatgat tcgtaacttg caaaaaaacc atgccgtcca gtcagaacgt acccttctaa
     1021 gaacccttca tcttggtgtt ccgataattg actgtcgatg acgcgaccag atggcgaaag
     1081 ccattcatca ttttctggtt cgattttttc catccattgg cgatttgtcg ttttgaaaac
     1141 ttgattcaat cggtttgatt ttgtttcatc tggtccaaat atacggaaat tttctggatt
     1201 tttctcaatg atctcgcgaa cgaatttacc aagttcggtc atatcttctg ctttaacgga
     1261 gcctggtttt tcaaattgca aagtatattt tttccaatct ggcataataa gcggtcttgg
     1321 atcgattcca ccattggtga taggattttt tgccattctt tggtcaccag taggcgcaat
     1381 ttctctgatt tcttctaaaa tacgtccttg tgcatcaaat aatttttctg gttcatagga
     1441 tttcagccaa cggagtaaag catctgcatg atccatatgt tcttgatcta caggaatcgg
     1501 tacttggtgt gctcggaagg ttccttcaat tggttccccg tcccattctt ttggaccggt
     1561 ccatcctttt ggtgtgcgta cgatcaatac tggccatttt ggcatcacga catctgttgc
     1621 tgtcttcagg cgagcttctt tttggatgga tttgattttc tcgattgctt gatccatttt
     1681 ttcagccata acaggattta atttttctgg atcatttcct tcaataaaga aaggctccca
     1741 gccaagtccg ttaaagtaat ttgctaattc tccatctgat ttacgtgcca agatcgttgg
     1801 gttggctatt tttgcaccat ttaaatgaag gatcggtaaa acagctccat ctatcactgg
     1861 attgataaag acatttgaga accagcttcc agctaaagga ccggtttctg cttcaccatc
     1921 accaatcacg acagcagaga ttacttcagg attgtctaat acagctccga ctgcatgtga
     1981 aagagagtat ccaagctctc cgccttcatg gatagaacct ggtgtttctg gtgctgcatg
     2041 agaagcaatg cctccaggaa atgaaaatcg cttgaataat ttttgcattc ctgtctcatc
     2101 ttccgttact tctggataga tctctgtgta acttccatct aaataagcat tcgataccat
     2161 gacttgtccg ccgtgtcctg gcccttcgat ataaaacatg ttcaaatcat atttattgat
     2221 gactcggttc aaatggacat aaataaaatt ttggccagga atcgttcccc aatgaccgat
     2281 tggatgtttt ttgacatctt ctggtttcag tgtacgtctc agtaaggggt tatctttaag
     2341 ataaagttgc ccaacagaaa gataattagc agcacgccac caagccgtca ttttatcaaa
     2401 gtattcttta ctagaataat ccatacataa cactcctttt cattattact cttattctag
     2461 cgcagatact cccaattgaa acctaataag cacttctgtt catttgtttg gattttatat
     2521 ctagccaaat gaacaggtat aaaaaaccac gaaatttttc ctttcgctga cgttttttac
     2581 attgatccaa aaaacttgtc gttatcacaa tggctgttcc gcagttcatt tcgctcctca
     2641 tcatgcataa tttgctgaat gacgctaggc cagttaacac attgttggaa aactggggct
     2701 ggatcgagca attcctttcc tgattgatcc gttttatgta aaagtctctg ttatctttgt
     2761 caatatgtga attggtatcc cagctactat gctaatttct acagggatta tccaaaattt
     2821 ggatcgtgac caaatcgaag cggcgtaatc ggaaatatca ataacttcaa cgtgattttt
     2881 cttttaactg tcaacggacc gacaaactca aacttttatg gtgcaggttc cactgatctt
     2941 ctagttactt ggctatacct gactgtcact aaaatagatt acaatctagc ttccgttatc
     3001 ggtatcttga tctttatcta tatgcaaaaa tttatatact atagaaaaaa gaaagtcgaa
     3061 ttttttactt ttctttttct cttttttggt tagctgacac gctaccagac taaagtcatg
     3121 gaactcttag gtaatacgtc ttaatgaaaa caaaaaaatc ccgcaacccc tgatttcaca
     3181 ggatttgcgg gattttttga ttagtctttg ttcaagtcgc gaagcaattc atcgatatgg
     3241 ttcccataga caactgattc atcaagttca aagaacaatt caggtgtctt ataaatactt
     3301 agattgtgcc ctaactctcg acgaatcaat cctgatgctt tattcaatcc atcttgtgct
     3361 tttttcttat ctgatgctaa gtcagataaa atgctgtaat agatcgttgc ttgctgtaag
     3421 tcccccgtaa ctttcacatc tgtgatcgtt acgttctcca cacgagggtc acggaccttt
     3481 ttgcgcaaaa tatcattgac ttcttttaag atttcttgac cgactcggcg atcacggtag
     3541 ttagccataa tgattggcct ccttttatca gtttttagtc atttttgact tcttccatga
     3601 taaatccttc aattacgtca tctactttga tgtcattgaa tttttcaatc atcgcaccac
     3661 attcataacc cattttgact tctttcacgt catctttgaa tcgtttcaga cttgcaagtt
     3721 ggccttcata gattacgatt ccgtcacgga ttacacggac accgctatct ctacgaatat
     3781 atccttctgt tacataggca cctgcaatcg taccaacttt agaaactttg aaggtttcac
     3841 gaacgatcat ttgaccggtg attttttctt caaattcagg gtctagcatc cctttcatcg
     3901 cagtttcgat ttcttcgatg gctttataga tgatacggtg aagacgaata tcgacttctt
     3961 cagtatcagc ttgcactttt gcctgcggtg taggacgaac gttgaaaccg atgataatag
     4021 cgttgctggc tgctgctaag gttacatcac tttcattgat tgctccgaca gctgaatgga
     4081 cgatttttac acggacacct tccacatcaa tcttcttcaa tgatgcagcc agtgcttctg
     4141 ctgaaccttg tacatctgct ttgatgatta cgttaacttc tttcaattcg ccttctttca
     4201 ggctttcaaa taagttgtcc aaagtcacac ggcttgtggc agcacggttt tccaataatg
     4261 cacgttttgc gcgttcttca cccgctgcac gtgctgtctt ttcgtcttcg aagactacga
     4321 aacggtcacc tgcttgaggt acatcattca agccagtgat ttctactggc gttgcaggtc
     4381 ctgcttcttt atcgcgacgg ccaagatcgt ttgtcattac acggacacgt ccgtaagtat
     4441 taccgacaac gattgggtca ccaacgtgaa gtgttccttc ttggacaagt aaggttgaca
     4501 caggaccttt acctttatca agacgtgctt cgatcactgt tccgattgcg cgttgtgttg
     4561 gatctgcttt taaatcttct acttctgcga ctaacaggat catttccagc aattcttcga
     4621 tgttttggcc gaatttcgct gagatctcaa caaaaatcgt ttctccaccc catgcttcag
     4681 gaattaattc atactcactt aattcttgca taacatgctg aggatttgca cctggtttat
     4741 caattttatt tacagcgacg atgattggaa cgcctgcagc tttggcatgg ttgattgctt
     4801 caactgtttg tggcatgacg ccatcatctg cagcaacaac taagatcgtg atatctgtga
     4861 tacttgctcc acgtgcacgc atacttgtaa aggccgcatg tcctggtgta tccaagaaag
     4921 tgattggttt accatcaata tcgatctggt aggcaccgat atgctgtgtg attccgccgg
     4981 cttcgccgct tgttacacgt gaatggcgca atgtatccaa taaggttgtt ttcccgtggt
     5041 ctacgtgtcc cataatcgtt actactggcg gacgtgagac taatttatct ggatcgactt
     5101 cttctgcctc gaagaattta tcgatatcag caatgtcaac ttggactttt tcttgtggtt
     5161 ccatgccata gtccgtcgct aacagttcaa tcgtatcttt atccagtgct tggttttgat
     5221 tgaccatgac accaagcata aataattttt taatgatttc tgctggctca cgatgaattt
     5281 ttttcgcaat atctgctacg ttcatacctt cagtatactc taatacatct ggcaattcac
     5341 ggaatttgcg tggtggtaca gctggtttag ttgattgttg ctgtttgcct tttttacctt
     5401 ttttattata acgattacgg ttattattat taaatttgcc gcgattgtta ttgtttggtt
     5461 tgttgttatt gttagtacgg ttttgattgc cgccttggct cgttccttga cgattttggc
     5521 tgctggtatt tcccgtatta ttttggtttg ttgttggttt ttttccttga ttcacttgac
     5581 cgctcccttg accgcgatct tgataactgc ggttattttt atttttttgt tgattgttcg
     5641 ttgtttcttt tttacgttga tcgttcggct gttgattggc tggttttctg cttgcttgtt
     5701 gtgcagcttg ttgtttcgtg cttgggtttt tgaacgcttg ttgcaatttc ttctcatcac
     5761 tgctagtaat cgcacccata tggtttttca catcgatgcc aagttgttgt gctttttcca
     5821 cgacgtcttt actagatttt ttgagttctt ttgctaattc atagattctt ttgttgccca
     5881 tgcaatcacc ttcctaacct tcaattagct ccttggtctt cttcgcaaat ccggcatcca
     5941 ttattccgaa taccttgcga ggttttccga tcatctgcgt gatttctgct tcagaaaata
     6001 gctcaaagca aggaacttca taatatgaac tcttatcttt tatctttttt cttgtattct
     6061 cacttgcatc ggttgccaca aacaccaatt ttgctttttg tttgcggatt tcagcaatgg
     6121 tcagttcttc acccgtgatt agttttcccg cgcgcatcgc tagaccgatg agattcatgg
     6181 ctttttgccg attaactgta ttcattttcc aaataactct ttacgtgctt tttggtgagt
     6241 gacatagtca agaagttctt gataaaactc atctgttaat gttgtttcga gtactcgatc
     6301 gagaattttt ttatcccaag cttgttgtac ttcttccggc tcaagtgaga catacgctcc
     6361 tcgtccaggc atttttccag ttggatcgat cgatacttcc ccttcttttg aacgggtgat
     6421 tcggaccatc tcttttttag gtttcatttc acctgaaacc acggatttgc gtaaaggaat
     6481 tttcctttgt ttcatctctt tgcctcctta ctaaagttaa gcttctggtt tttcttcgac
     6541 cgtttcattg ttgaatgcaa ttgtttcata ttcatcgtct gttaaatctg actgaacgat
     6601 tgcttcatca tgcagttctt ctgtttcttt ttgttgttct tgattttcat aaaattccgt
     6661 catgtcagat tctgatttga tatcgatttt atggttagtc aatttagcag ctaaacgtgc
     6721 attttgtccg cgtttaccga ttgctagcga taattggtag tctggaacga caactgtgca
     6781 ggcctttgga tttgtctcat cgaagatcac atccatgact tgtgcaggat tcaatgcatt
     6841 tgcgatgaat acagctggat cttcattcca ttcgacgata tccatgtttt cgccttttaa
     6901 ttcattgacg attgcttgaa ctcgttgtcc ctttggcccg acacatgtac cgactgcatc
     6961 gatatttgga tcatttgagc gaactgccac ttttgaacga tcgccagctt cacgggcgat
     7021 gctgacaatt tcaacgattc catcatagac ttctggtact tcttgttcaa ataagcgacg
     7081 caataggtct ggatggctgc ggctaacaaa tacttgcgga cctttagacg tattttctac
     7141 tcgggaaaca taaactttga ttcgatcatg tggttgataa aattcatttg gcatttgatc
     7201 ttgtttagaa agaactgcct caattttacc aagattgaca taaatataac gtttatcctg
     7261 gcgttcgacg attccttgca tgatgtcttt ttcataagca ctgaattcgt tataaataat
     7321 cgttctttct gcttcacgta cacgctgtaa aataacttgt ttagccgttt gcgcagcgat
     7381 ccgtccaaaa tcttttggtg ttacttcaaa acggatcgta tcaccgatct catatgctgg
     7441 attgattaaa agtgcatctt tcaatgagac ttccaactgt gaatccatca cttcttccgt
     7501 tacttctttt accgcataga catggatctt tccttttttc tgatcaaatt ccacttcgac
     7561 gttttgtgct tggccatagt gacgtttgta tgcagaaacc aatgctgctt ctaaagcatc
     7621 gatcacgatt tcttttgaga tccctttttc agcttctaaa gcgtctaacg catttaacat
     7681 ttctttactc atttttttct gattcctctc cgtgattaaa attggatagc taagcgagct
     7741 tttgcaatat tttttcggtc aaaagtcaat tctttttctc gtgtttttat gcgtattttc
     7801 aatgtaagct gttcagcatc aaatgattga agaaatcctt catattgttt ttcgccatct
     7861 actggttggt ataaggagac atggacataa tcaccaagtg ccttttcata gtcgctttct
     7921 tttttcaatg gccgctctgc tcccggggag gatacctcca ggaaataagc ttgaggaatc
     7981 ggatctggat ctgctgcatc aagtttttca ctcagtttct cactgacaaa ggcgcattct
     8041 tcgatatcga taccgccttc tttgtcaata aatactcgta agaaccagct ttttccttct
     8101 tttacaaatt cgacttcgac aagttcaaaa ttttgttcat ctaaaatcgg tgtcaccatt
     8161 tctgtgactg tttcaacgac gctactcaaa agtttcgcct ccttaaaaat taagtgcgta
     8221 attccattaa aaagagtgag cgaaaaatcc gctcactcac agttagtatc attacctata
     8281 agaactatac catactctgc ttaaaattac aagcagacag gaaaacagat gcttatagca
     8341 tatcgaataa cgataattga ttttcatctg gtagatcttt caatacgcca ttgtcgttca
     8401 tatattcgat caatgttttt gaaactttac cgcgggtggc aagatcttct ttggataaaa
     8461 atggaccgtc ttttcttgct tcaacgattt gtttcgccac gttggttccc aaacttggga
     8521 cagctctaaa tggtgcgatc aacgtatcac cttcaataac aaagttaacg gcatccgatt
     8581 tatacaaatc aatcattcca aatttgaatc ctcgttccag catttcattg gctaactcca
     8641 gcactgtcag ttgattcttt tcttttacgg aagcatctaa tcccttgtcc gtgatttctt
     8701 tcattgcttg tttcacagca tcttttcctt tgcacatgga gactagatca aagtcgtctg
     8761 cacgtacaga aaagtatgca cagtaataca aaatagggaa ataaaccttg aaataagcga
     8821 cacgaagagc catcaatacg taagctgcag catgggcttt cggaaacata tatttgattt
     8881 ttgaacaaga atcgatatac cagtcgggca cattattttc tttcatcgcc gatagatagg
     8941 tttctcgcaa ttcatcaggg atcttgttcc attgtccttt acgaacagtt tccatgattt
     9001 taaatgccat cccgctatct aatccagcat ggatcaaata aaccataata tcatcacgac
     9061 agccgattac ttccgccagt gtcgcatctc ctcgtcgaat caattcttcc gcatttccta
     9121 accatacgtc tgtaccatga gatagtccgg aaatttgcag tagttctgca aaagttgtag
     9181 gatgcgtttc ttctaacatc cctcgaacaa aacgagtgcc gaattctgga atacctaatg
     9241 tccctgtttt ggaataaatt tgttcctgac ttactccaag tacttcagga ccggcaaata
     9301 tccgcatcac ttccgggtca tccgtaggga tcgtttgtgg gtcgatccct gataaatctt
     9361 gaagcatccg aataacagtt gggtcatcat gccctagaat atctaatttc aatacattat
     9421 cgtgaatcga gtggaaatca aaatgagtcg ttttccattc tgaattttga tcgtctgctg
     9481 gatattggat cggcgtaaaa tcatagacat ccatataatc gggaataacg atgatccccc
     9541 ctggatgctg gccggttgtc cgtttgactc cagtagcgcc ttttgctaat ctgtcgactt
     9601 ctgcacttcg aaactgcaga ttattgtccc tttcgtatcc ttttacatag ccatatgctg
     9661 ttttgtcggc gactgtacca atcgttccgg cacggtaaac atagtcttcg ccaaacaata
     9721 ctttcgtata gttatgggct tctgcttgat aatcacctga gaagttcaaa tcaatatcgg
     9781 gcactttgtc tccatggaat cctaaaaatg tctcaaatgg aatatcatga ccgtctttgt
     9841 ttaagcgtgc accacatttt ggacattgtt tttctggcat gtcaaatcca gaaccatacg
     9901 taccatcttc aaaaaactcg gaatattggc actctggaca ataataatga ggggctaatg
     9961 gattaacttc agtgattcct gtcatcgtcg caacaaagct agagccaaca gagccacgtg
    10021 aacctactag atagccatct tcattacttt tatgcactag tttttgggcg atcagataaa
    10081 taaccgagaa gccattacca ttaatagaat tcaactcttt ttctaatcgt ttttgaatga
    10141 tctcaggtaa cggatctccg tacatttgtt ttgcttttgt gtaactcaat tctgatattt
    10201 catcttctga acctggaatc ttcggtgtat aaagttcatc tttgactgga atcacttctt
    10261 cgcagatatc tgcgatttta ttcgtatttt ctactacgat ctctttcgct gtttcttccc
    10321 ctaaaaagtg aaatgcagtt agcatctcat cggttgttcg gaaatggaca tccggcaaac
    10381 tatgacgatt caacggattc gctccgccca tagaattgat caaaattttt cggtaaatgg
    10441 catcttcttc gttcagataa tgtacattac ctgttgcaac aacgatttta tccaaacttt
    10501 ttccgatttc taccaaattt tggataattt cttccaaatc atgttcattt tttaccaatt
    10561 cttgctcgat caaaggcgca tagaccgctt ttggcataac ttcaatataa tcatagaatt
    10621 ttgctcggtt tcttgcctct tctacccctt tttgcatcat ggcttcgaat atttctccct
    10681 tatcacaagc tgagccgatc aatagatttt cacgcatctt tttcaattgg gagcgtggta
    10741 ttcgtgggac gcgttcgaag tattcgacat tcgacattga aatcagtttg aacaaatctt
    10801 tcagtcctgc ctgatttttt gctaaaatcg ttacatggaa aggtcgagcc cttttgtaag
    10861 aatctccttc tccgatatgc tcatttagct gatcatgata aagcatgtta tgattgtcca
    10921 ttgcctcttt cacaaagatc catgctaagt gaccagttgc ttcagcatca tagattgctc
    10981 ggtgatgctg ttccaagcta acaccaaact ttttagataa cacacctaat ccgaaacgtt
    11041 tgaattgagg atacagatat ctagctaatt ccaacgtatc aatgactgga ttggccgctt
    11101 caggaatacc ataccttgcg tagctagtat tcaagaaccc catatcaaaa gccgcgttgt
    11161 gggctaccaa aattgtatct tttgaaaatt caaggaacat ccgcaatact tcttcttccg
    11221 actttgaccc tcgaaccatt tcatccgtga taccagtcag atctaccgtt gttcgtgaca
    11281 atggatgtcc tggatcgata aattcatcaa agctttcgat cacatttcct ttatacattt
    11341 tgactgcggc tagctcgatg atcgtgtcat atactgcaga caatcctgtc gtttccacgt
    11401 caaatacgac gtatgtggct tcactcaatg cttcatgtgc atcattataa gcaattggga
    11461 caccatcatc tacgacattc gcttccacgc cgtataagat tttcacacct gctttttttc
    11521 cagcactatg tgcttccgga aaggcttgcg caccaccatg gtctgtaatg gcgatagctc
    11581 ggtgtcccca ttttcctgct tgtgccacaa gatcagagat gctgtttgtt gcatccatcg
    11641 tactcatatt gctatgaaca tgaagctcta ctcgtttttc cccttcagga gcataatctt
    11701 tgcgaggtgt atgtttgact tctatgatat cttgcgcatt catgaccaaa tcacggacaa
    11761 acgtatcttc ttgaatactt cctcgtacct ttaaccagct accgacactg atcgcatcaa
    11821 atacttgttc atctttttcg ccgttcgaga attttttgac gataaatgat gaagtataat
    11881 ctgtgatttt caaagtcaag atcttgcgtt ttgaacgtag ttctctgact tctttgtcga
    11941 atacgtaccc ctcaagtgtg actcttcgtt cttcttcaac gatactgatc attggtgtcg
    12001 ttggttcatc ggctggaata tttcgtccta gctggatggg tccttcaaga gctggcgatt
    12061 gctcttttct ttcctttttc ttttgttcgt ggacaactag actttcagct gcttgcttca
    12121 taaaggcttc tgcctgttct tgtttgcgtt cttcaaaaag tttcaataca cgttccgctt
    12181 gctgctcatc cacttctggt tcgatacgaa attttgggaa tccgtaactg acgaacaact
    12241 cttctactaa tggcaagtat tgttgcttca aataagaaat agctcctgta ctgtcgattg
    12301 gcaagatgac tttacgatct tttatcacag gtacctgcgt tttcaatact tgctgtgcta
    12361 gtggtgtatc gcattgctga ttttccaaag cttgggccca gtaatcttgc aagagctgtt
    12421 catcgaatgt ctggtcatct gctaagatat tcagtttgac ttgtgcaata tctttaaaag
    12481 cgatagtcag atgctgagtc aatgaccgat atagcataat aggcaaaatt ttggaaaaat
    12541 gtagcgtaaa ttcccataaa cgcgatttac gatggaccac tacactatcc atttcaccag
    12601 cagtaagcag tggatgattt ttttctgctt cctctagttg gatttgttcc aacagttttt
    12661 caaataaatc tcgtttttct gacaaagata tacgcccttt ctgatgagaa acaatgcaat
    12721 tgatcgcatc ttatcctctt ctttttcagt accttttagt atactcgttt tttctgagtt
    12781 ttacattaaa aaattggaac tgcgattcaa atcgcagttc caattttaaa agcgaatcat
    12841 cagattgtca aaaacagctg attcagctat ttttattttc tgtgttttaa cgcttattat
    12901 tcgccttggt tcaagaggat tggtaaagta ttcgccaatt cttctttacg tacttcaacc
    12961 atttcgccag ttttcttgat tttcacttct acgattccat ccactgcttt tttaccgaca
    13021 gtgattctga ttggacagcc aatcaaatca gaatccgcga atttcactcc tgcgcgttca
    13081 tttctgtcat caaccagtac ttcatagcca gcttttgtca tcgcttcttc tagttcattc
    13141 gtcaggcttg tttggtattc gtcttttaga ttcatttgga cgatatgcag atcaaatggc
    13201 gcaattcctt ttggccaatt gattccttgt tcatctgaat gttgttctac gattgctgat
    13261 aataaacgac ttacaccgat accataacag cccataatca caaatttttc tcgtccattt
    13321 tcgtctagta cagttgctcc catagattca ctgtaacgag tgccgatttt gaatatatgt
    13381 ccgatttcga ttcctcgagt aaaggcaaga acaccgttgt tgtctggtga aggatctcct
    13441 tcttgtacaa aacgaagatc ttcataagaa agcacagtga aatcgcgttt tggattcaca
    13501 tttttatagt ggaatcctgt ttcgttcgct ccagtaatgg cattcgctaa atcttggaca
    13561 taacggtctg catatacttt tacgtcatct gaaacaccga ctggtccgac agaaccaaac
    13621 tcagcaccta gatatttttg tgcttcttct tctgttgctt cttctaaaaa gtcagcagat
    13681 aaaaagtttt tcagttttac gtcattgact tcatggtctc cacgtaccaa aacaaggaca
    13741 ggttgttcat ccgcaatgaa caatacagac ttgatgattt tttgaggttc aacagaaaag
    13801 aaatctgcta cttcgtcaat tgattttacg ttaggtgtag ctactttctc caattcaagc
    13861 tgtgtttcat gcgatttttt tgatacatag tagcttgtag ccatctccaa gtttgcagca
    13921 taatcacttt cagtcgaata acagatcgta tcctccccga tttctgagat cgccatgaat
    13981 tcctttgagt ctttcccgcc cattgcgccg ccgtctccga tgatcgagcg aaattctaag
    14041 ccacaacgct tgaatacttc ggtataggct ttttcgtaat ctttatatgt ctcgtccaaa
    14101 ctttcttccg ttgcatggaa agaatatgca tctttcatga taaactctct tccgcgaagc
    14161 aaaccgaagc gaggtcgttt ttcgtcacga tatttaggtt ggatttgata aagatttaaa
    14221 ggtaatttct tatatgaatt gatttcatta cgcatcaaat cagtaaaagt ttcttcgtga
    14281 gttggtccaa ggatcatttt tcgatcattg cggtctttga aacgatacaa gtttggtcca
    14341 tatgtttcgt aacgcccgga ttcttcccaa agttctgctg gcaagatggc aggcatcagc
    14401 atttctaccg ctccgatttt ttcaaattct tcccgcataa tgcgtttcag tttttccaat
    14461 acacgatttg ctaatggcag atatgaataa atacccgctg atacttggcg gatatatcca
    14521 gctcttagca agatttgatg gcttaatact tctgcatcat ttggaacttc gcgtaatgtt
    14581 ggaatcaaca tttttgattg tctcattcta tatactcctt tatttcctca aaatagttat
    14641 cgtttgttat tataccctat ttgtcaactt tttctagaaa aagaatcgtt gaatatcgtt
    14701 ccatgtaact agcaccatca acaacattaa aaatccaaag ccagctaatg tcaatattcc
    14761 ttctttttct tgacttaatg gtttcccgcg aatcccttca aaaatattca agactaattt
    14821 cccgccatct aaggcaggaa tcggaagcag attgacgatt ccgagattca ttgaaagaag
    14881 cgccatcaaa ctaataacag ttgttacacc ttgatttgct gcttctgaag acaattggta
    14941 catcatgaca ggtccgccta atttatctaa actgaaacct gtaaatagtg atcctaaggc
    15001 tttgaaaatt tccaatgaac cgctgaaagc ttgacgcgtc cctccaatga tcttatccat
    15061 aaaacctgta ttcattgggg cttttatacc aagttggcca actttttcgc catttgactc
    15121 tacagatttc ggtgtcacgt cgacagattg cacctgacct tctcgttcga tcttaaagtc
    15181 taatgtttta cctggatttt tcgtaatgac tgttgtcaga tcattccatg aatggatttc
    15241 ttttccgtcc acactgacta cctcatcatt ttcttttaag cctgcttctg ccgcagctcc
    15301 attaggcatg atctctccta cgcgattagt gttcgtcact tgaacaccac cttgcataaa
    15361 tgccagaatg atgaataaca cgattgccaa aataaagtta ttcatgggtc cagcaaagtt
    15421 ggtcagcata cgctgccaca atttagccga ttggaactgt acgtcttttg gcgcaattct
    15481 gatttctgtt ccgtcgtttt caataatcgt cgcatcgtga tcaacagggt aggttactac
    15541 ttctgtttcg tctccattca cataaccagt gatagtcagc tcatcttcta aatcataacg
    15601 gctcaattcc atcgggatag catttgtcaa ttggattttc ttacttaaat ttatcttctc
    15661 tacgatgccg tcagaattta gtaaaagaga aagaggcatt cctggtgcca tttctgtttc
    15721 atcatcccca ttgcctgcca ttcgaacata accgccaata ggtaataggc gaagcgtata
    15781 tgttgtcccg tcttttgctt gatgcccata aattttcgga cccataccga tagcaaattc
    15841 gcggacgagg attcctgatc gtttcgcaaa gaagaaatga ccaaactcat gaacaatcac
    15901 taatatacca aaaacgatga taaatgtcag aatcgttttc atagcttttt tctcctttac
    15961 ttgttttttg tgttttttat aaaacaacga taaaacacta taattttacc atagtatacc
    16021 aaagacacca atagtatcaa tataatgaaa aataaaaacc tgcgtctttt atgaaattca
    16081 caaagaaacg caggtatact tactaaataa tgccaaataa atgcatgata ggaaatacaa
    16141 acagcaaact gtcgaaacgg tctaagattc caccatggcc tggtaagata tttcccgagt
    16201 ctttcacatc ataatgacgt ttgattgcag attcgaccaa atcaccaaat tgtccgactg
    16261 ctgaaaaaat aatcgtcatc agaagcatga caaacatacc atgattgaat agttcttttg
    16321 ctgggtatag caataaataa agaaatgcga ctacaacagc actaccgata ccaccgagcg
    16381 caccttcaat cgttttgttg ggcgaaatat caggacttaa cttatgctga ccataacgtc
    16441 gaccaaccat atatgctccg atatcagttg cccaaacaat aaatagacca aatatcaaaa
    16501 cagccaagct ttctgttcgt gcattgacaa aattctggaa acctattccc acatacaagc
    16561 tgacaagcac aggaaaacct gcttcatcaa tcgtatacgt atttttagaa ataactgatg
    16621 ttcctaaaag aatcataact ataagataaa ataacataaa tgtacttaca ttctctggaa
    16681 gaaagaaaaa ccatctttct tttggcaaaa caagtaacac tgcaccaacg gcggataaaa
    16741 ctccttcaaa acttaagagt gtcaatcctt tcatccggaa cagctcgtaa actcctacta
    16801 ccgctaagat tgctgctgta agctcaaccg ctatgcctcc gatccatata atcggaataa
    16861 acaagactag cgccacagct gctgtgatca cacgttgttt catgactgat cccctttctc
    16921 atcttctgtt ttttttacac cgccgaatcg acggtctcga ttttgataag aggcgattgc
    16981 ttcttcaaga tgcgcaccat caaaatcagg ccaaagcgct tttgtaaaat acagctcact
    17041 atatgcgatc tgccataaca gaaaattact aattcgctct tctccacttg tacggatcat
    17101 cagctcagga tcttgtaact ctttaggcaa gaaacctgtc attaaatgct tagcaatcaa
    17161 ttcatcatcg atttcttctg cgtgtatttc tccttttgct acttcttcgg caatttcttg
    17221 gacagcagtc acgatctctg ctctacttcc ataattcaaa gcaaaattca ataccattcc
    17281 agtattgttt tttgtttgct caattgcacg tcttacagca tcttgcgtat gttctggcaa
    17341 tacgttttca taacccatga catgaacttt gacattttct ttaatcaatt ctggtacgaa
    17401 cgtatcaaag aagtcgacag gtagttgcat gagaaaactt acttcatctt ttggtcgctt
    17461 ccagttttca gtcgaaaagg cataaagcgt caacactttc actccaagcc ttgatgcttt
    17521 ttttgtgact ttctttactg tttccatgcc ttctttatgg ccagcaactc gtggcaaacg
    17581 acggttttgc gcccaacgac cattgccgtc catgatgatg gcaatgtgct gaggaattgg
    17641 tccatcggta ttaaattgaa attcgctttt ttcttgaata tatttgtttt tttgcggaaa
    17701 aaaacgtaac attctttttc ctcctatact taaaagattc ccactatctt aagtattata
    17761 gcaatatcta actgtttttc ctatgaaatc attgtttttt tatttaaaaa ctgaataatt
    17821 ttttcttttt ttaattttta aataaaagaa atataaataa aaacagagga agcggaatga
    17881 tccgcccctc tgtttttatg attttattaa acttccaata attctttttc tttatcagca
    17941 gcgatcttat ctacttcttt aatgctgtta tctgtcaatg tttgtacgtc tttttctaat
    18001 ccgcgcaaat catcttcggt aatatcacca tttttttgtt gttttttata ttcatcgatc
    18061 gcatcacgac ggatgttacg aatcgcgatt tttgcatttt ctgcttcttt tttcacatct
    18121 ttagctaatt cttttctgcg ttcttctgtc agttgcggga taactaagcg aatgacattt
    18181 ccatcattgg ttggactgat tccgatatca cttgccataa tagctttttc aacatcttga
    18241 agaatgctct tgtcaaaagg tgtgatcatt aaaacacgtg cttctggaat ttggattgat
    18301 gccatttggt tcaatggtgt tggcgcaccg tagtagttca cagtaatacg gtccaaaagg
    18361 ctagcgttcg cacggcctgc gcggatttgc ccaagttcac gttgaagatt ttgtgctgct
    18421 tttttcattt tttcttttgc ttctgtcata attgcatctg ccatttttat ttccccctta
    18481 cagttgttcc gatattttcg cctaagattg cacggcgaat atttccgtgt tcatttaaat
    18541 tgaagacaag cagtggaata tcattatcca tgcttagtga acttgcagtt gaatccatga
    18601 cttgtaatcc tttggcaata acttccagat gagtcagttc ttcaaatttt actgcatttg
    18661 catctacttt cggatcagca gaataaacac cgtctacatt gtttttagcc atcaggataa
    18721 catctgcgcc gatttctgcc gctcgtaatg ctgctgttgt gtctgtcgag aagtacgggt
    18781 tgccggtacc gcctgcaaag ataacgatcc gtcctttttc taaatgacgt tctgctttac
    18841 ggcgaatata tggctctgcg atttgacgca tttcaatcga agtttgcacg cgtgtcggta
    18901 cacccacgtt ttccaacgta tcctgtaaag ctaaggcatt cataactgta gctaacatac
    18961 ccatgtaatc agcttgagca cgttccatgc ccatttgtgc tccgatttgt ccgcgccaga
    19021 tatttccgcc acccacaacg attgccattt caacgcccag ctcgtgaact tctttgattt
    19081 cttggatgat ttctttgatt actggtggtt tgattccaaa tcctgcatcc ccagctaaag
    19141 cttctccact caattttaag actacacgct gatatttcgg tgtgaccatg ttcattcctc
    19201 caatattttc tattgccatt ttaccatact tagatgattt cgacactcta agactggttt
    19261 ttcttgtttt gcttaaaaaa agggagcgca caaaccgtgc gttcccgtct gttattcaac
    19321 agaattattt tttcacttgg ctcataactt cttctacaaa gttatcttcg cgtttttcga
    19381 taccttcgcc aacttcgaaa cgtacgaatg ttttaacagt tgcgcctttt gatgcaacgt
    19441 atttttcaac agtcatatca ggatctttaa cgaatggttg gtccaccaaa gcgatttctg
    19501 ctttgaattt cttcaagcgt ccttctacca ttttttcaac gatattcgct ggtttgcctt
    19561 cgttcaatgc ttgttctgta agaacagttt tttcatgttc taattcagct tctggaattt
    19621 gtgattcgtt tacataacga ggattgatag ctgctacgtg catagctacg tctcttgcaa
    19681 ctgtttcgtc agttgttcca tctagaacag tcaatacggc aatacgtccg cccatatgca
    19741 agtatccacc aaatgcagca ttgtcgtctt tttctacaac ttcaaagcga cggaagctga
    19801 ttttttctcc gataacttga gttgcttcga tcaagtcaga ttcaattgta cctttatctg
    19861 ttttgatttt cattgcagct tccatgtctg ctggtttgtt ttcagcaaca agttctgcaa
    19921 tttcttttac taaatcttgg aacatttcgt ttttagaaac aaagtctgtt tctgagttta
    19981 cttcaacgat tgctgcagtg ttacctttca cagcaactga agccaatcct tcagctgcaa
    20041 tgcggtcatt tttcttcgca gcctttgcca ttcctttttc acgtaaaaga tcaactgctt
    20101 tttccatgtc gccttctact tcaactaatg cttttttcgc atccatcatt cctacgccag
    20161 tcatttcgcg tagttctttt accattttag ctgtaacgtc tgccatgttt aactcctcct
    20221 gtgtgttttt ctttttaaaa aaagctgctt caaaggagag tgaggcttgt cgcccagcct
    20281 ttgaaacagc tccatcattc aaaattattc tgctgaagaa ttgtcgcctt caacaacatc
    20341 tacgatttct tcgattgatg ttgctgtgtt ttcttctgtg aaatcttctt caactacttg
    20401 atcttcacct tggtttcctt cgatgaaagc atcagccatt tttgaagtaa tcaatttaac
    20461 ggcacgaatt gcatcgtcgt ttgaagggat tactacgtcg atttcatctg gatcgcagtt
    20521 tgtatcaacc atagctacga ttgggatatt taatttgtgt gcttcttgaa cagcaatacg
    20581 ttctttacgt gggtcaacga tgtacattac atctgggatt cttggcatat cagcgatacc
    20641 gcctaagaat ttttcaagac gttcacgttc tttgttcaaa ccagcaactt cttttttagg
    20701 tagaacttca aaagttccat cttcttccat tgcattgatt tgtttcaaac ggctgatacg
    20761 tttttggata gtatcccagt ttgtcaatgt tccgcctaac caacgatggt taacgaagta
    20821 ttgtcctgca cgagttgctt cttctttgat tgcttcttgt gcttgttttt ttgtacctac
    20881 gaataatgct acgccgcctt cttcagcaac gctcttcatg taatcataag ctgcatctac
    20941 taatttaact gttttttgca agtcaatgat gtagattccg tttctttctg tgaagatata
    21001 tttcttcatt tttggattcc agcgacgagt ttggtgacca aagtgtacgc cggcttctag
    21061 taattgtttc atagaaatta ctgccatgtt tgtttcctcc gatttggttt tatttttcct
    21121 cttcttatct tctaccttgc cggcaaactt tttcaagcac ctaccgacaa tccaataaga
    21181 atgtggattt gctgatgcat aaagcaccct cagctattat acagacaaaa gatccgtatc
    21241 gcaagagcaa atatactttt ctgctcaaca ttcaatagtt tacctgaaag ataaaaagaa
    21301 ttcaagaaaa acagtagatt tctctttgtt tctttattat cctttttcca taaaataatt
    21361 ttaggtataa aagacgaata ttattgggca atccttcttt tttttgttat gatacatgtg
    21421 aaatctttcg taaaggagaa agaaaatgcg caaagctcaa agacatttgc tgattaaaca
    21481 agtcattgaa gaattcccga tccgtacgca agaagaacta ttaaacaaac ttgggcatta
    21541 tggcgttacc gccacgcagg caacgatttc tcgagatatc cgtgatctaa aaatcgtgaa
    21601 ggcacctgat gaaaatggcg tttcccgctt cgtattgttt cgcgaaaaag gaactcctga
    21661 gactaggact gaggaagagg atcggctggt tcaaatgatt gaagacattg tattgaaagt
    21721 cgaacgagtc cactttttga cgatcgtcaa taccttgcca gacaatgctc atttatttgc
    21781 atctgtttta gatgagatca aacctccctc tattgtcagt acaattgctg gattcgatac
    21841 gatcatggtc atctcggaaa atgaggagga cgcaaaacga gtagaagaat ttcttcacca
    21901 tccaactgaa gtatcacttt tttaatcaga gcacgtattc ctaatatgga atgcgtgttt
    21961 ttttattttc aatattttcc ttattaaata aacctttaca ctctttacaa aaatacatca
    22021 ttttttattc aattttttca acaccttgat tgaatcacaa taatcatcat ttatattgga
    22081 tgttaacaag agcagcttct tgctctttgt gtatttcaaa aaagaaatga aaggaaatca
    22141 tatgtataaa ttattaactc ctggaccatt gacgacttct gaaacagtga aaaatgctat
    22201 gctgatcgat cattgtactt gggatcaaga atacaaagaa attacacaat ggataagaaa
    22261 aaaattattg gatcttgctc aagtatcgga aggaatatac acaacggtct taatgcaagg
    22321 tagcggctcc tttggggtag aatcggtatt aagttctgtg atcaggccag aagatactgt
    22381 actgatttgt tcaaacggcg catatggaca acgaatgatc aacatgtgcg aatgtctgaa
    22441 actgaactat accgtttatg aggtatcgga acatcaaatc ctccaagctc atgtgattac
    22501 acagctgatt gaagagaatc cctctatctc cgcactagca atggtccata gcgagactac
    22561 ttccggtatt ttgaataatt tggaagagat tgctgctgtc acacaagaaa aagatctttt
    22621 gtttatagtg gacgcgatgt caagctttgg tgggataccg attcgtgtag ccgaactagg
    22681 gattgatttt ttgatttcca gctcaaacaa atgtattcaa ggtgttccag gcttttcttt
    22741 tgtacttgct aataaagcgg aactagaaaa gcgaaaaaat gtgagtcgaa gtttgtcact
    22801 tgatctatat gaccagtacc gcgtgatgga aaacgagaat ggcaaatggc gtttcacttc
    22861 ccctacccat acggttttgg cttttcaaca agcgctgaag gaactagagg cagaaggagg
    22921 aatcgaaact cgatattcac gttatctcgc caataatcat gtactacgac aaaaaatgac
    22981 agagatgggg ttccagcctt tcattcaaga atatcagggg ccattcatca cctcttttct
    23041 ttaccctaag gactggcgat ttgattttaa tcatttttat cagtatttaa agcaaaacgg
    23101 atttgtgatc tatcccggga aaatcagcga tcatgaatgt tttcgtatcg gaaatattgg
    23161 cgagatctat ccggaagata ttttggaact gacagcaatt atcaaagact ataaggagaa
    23221 cgttaatgat taaaactgta atttttgatt gggcaggaac aactgtggac tttggctgta
    23281 tggctcctgt ccacgctttt agaaatgctt ttctagaaaa aggaatccaa ctgactgaca
    23341 aagaaatccg cgaaccgatg ggaaaattaa aatgggatca tatccaacag cttctttccc
    23401 tcccttctgt caaaaaacaa tggatagcta tttatggaca actacctcag gaaaaagagg
    23461 tggaggaatt gtatcaacaa tttgaacatt atctgtttaa agatttggtc aagcattcta
    23521 ccttgaaacc cgacacattg gaaacgatcg aacggttgag aaacgctggg atcaatattg
    23581 gttccacgac tggatttact gctcctatga tgacaatcgt agcagaaacc gcaaaaaaag
    23641 aagggtattc accagacttc atggcaactt ctgaagacgt cgaagggtat ggtcgaccgt
    23701 ttccttatat gatccataaa aacatgcagt acttcaaaaa caagtcggtt gatgaagtaa
    23761 tcaaagtcgg agatacggtc tcagatatcc aggaagggaa aaatgccgga gtgttgacag
    23821 taggtgtaat tgaaggtagt tcgctaatgg ggatttctta tgatgagtac caaaaattag
    23881 agatggggaa aaaagatcgt ttaaaacagt ctgttgctct tagattccaa caagctggcg
    23941 ctgatatttg tgtaaacaat ttaaaagagt taacagaata cattttgtac gctgacaaga
    24001 atccagaatg acttttatac aaaatcagag gtcgtgaaaa agctgtactg catcaagtaa
    24061 taagaacagc caaacaaaaa tagctcctca tatttttcgt ttggttaggc ttattaccgc
    24121 agatgcaagc ttttgaacac cgtttattcg aaaaaaaaag ggagctgtga cacgactttt
    24181 gtcacagtcc ccttatttac aaacaaacag tgtttaagag acaacctctc cactaaacgg
    24241 tgttcattca gctgactctc ggtatttgct caaaaaacga taaaatttga aaagctattt
    24301 tctcttttgt ttctctaata ctcggatcag aacgctgatt tcacattctc tttttcttac
    24361 atcttatctg gtgcatgaag tcctagcaaa cgaaggtctt ctttcaataa tacagtcact
    24421 gcataaacta gagctaagcg tgcttctttt tgttcatcat cagctaaaat cttcgtatga
    24481 gcatagtatt tgttgaatgc ttgtgctaat ttgattgcat gtttcgcaat cactgacggt
    24541 tcgtattttt ccccagcaga caagaccgtt tcagggtatt tttgaactaa tttaaccact
    24601 tcccagctgg tatcgtcatt caatgcatag tctgctgttt ctgaagggac aaatcctgct
    24661 ttttccaaca ggctgactgc acgagcatgt gtatattgca cataaggtcc agtttctcct
    24721 tcaaatcgaa caacttcttc caggttaaag tcaaatgtat tcagtcgatc gtttttcaaa
    24781 tcgtggaaaa tgactgcccc aaccccaact tgtttagcta cagcatcttt gttttccaaa
    24841 tcagggtttt tctcgctgat ttgttcttta gcagattgga ttgcttcatt taatacttct
    24901 tctaataaga cgatctttcc tttacgagtt gataattttt taccaccttg cgtgatcaaa
    24961 ccaaatggaa tatggcgcat atcgtcagac cagtcaaagc ccatttcctt caagacagct
    25021 ttcaactgtt taaaatgata gctttgttca ttccctacta catatagaga ttgtttgaag
    25081 tcgtaagtac gtttacggta caatgcagca gctaagtcac gtgtaatgta tagtgtcgca
    25141 ccgtctgact tcttaatcaa cgctggattc aggtcataag cagataggtc aacgatctct
    25201 gcacctttat cctcgttcag caaatgtttt tcttctaaaa gtttgacgat ttcatccatc
    25261 ttgtcattgt agaaagcttc accgttcaac gaatcgaaac gtacttccag cagatcatag
    25321 attttattga attctttcat cgattcatca cggaaccatt gccataattg aatagcctct
    25381 tcatcgcctt cttccagacg tttgaaccaa gcacgagctt cttcatttaa ttctggttct
    25441 gtttcagcta cttcatggaa ttggacatat aaacgaagca attcattgat tggttctgct
    25501 ttaacagctt cttctgtacc ccattttttg taagcgacga tcagttttcc aaactgtgtt
    25561 ccccagtcac ctaaatggtt gatgcggatt ggctgataac cgattttttc cataatgaaa
    25621 ccgatcgaat taccgataac tgtcgaacgc aaatgtccca ttgagattgg tttggcaata
    25681 ttaggagaag acatgtcgat tggtactgtt ccttgattcc cgatattgct atccccataa
    25741 tgttcttttt ctttcactac tgtttgcaaa acttttttgc tgataagttc tttattcatg
    25801 aaaaagttca agtaaggtcc gacaacttcg attttttcaa agttggcaga atcgattttt
    25861 tctgctaaat ctgcagcgat ttgctgtggc gcttttcggt aaacttttgc taatgaaaag
    25921 gctggaaatg caacatctcc gtgttcagct gattttggat tttctagtaa ttgttcgact
    25981 tgttccagtg ttaaatcatc tttgacagcg tcatagacag cttttgcgac aagatcttta
    26041 ttattcatct ttattcctcc taaagtgctc ccttgattgt taaacaaaaa aaatctctag
    26101 cgacggcata cttagtatgc catcactaga gacgagattt cccgcggtac cactccaatt
    26161 gtcctaaaaa aggaccagct ccatctgata tcggtagacg accgtctgtt taaaacagaa
    26221 ttctccaagt gcgcttcgtt gtatcttctt cattcggctt ccaccacttc cgaattcgct
    26281 agccaagaat gatacaagta ctctcttgtt caacaaatct tagtcttatt aaactttctt
    26341 gaattatatc agaaaaaaaa acgaaaggct agtcgtttct gataaaaaaa caatccagat
    26401 ggcctaaagg agaagaaata ccacctggat agctataaat catttcgtaa atacgaaaga
    26461 cttaacaaat taatcagcta cgataatcgt tccttcttca gaagctaaaa gattctcgat
    26521 attttctaaa gaagtgatga ttgccttagc gtttggtttt gcttcaacaa atgcaatagc
    26581 tgcctctact ttcggaagca tgcttcctgg agcaaattgc ttttcatcaa tgtattgttt
    26641 catttctgaa acagtaacag tttctaattt cttttgatct ggtttttggt aattgacata
    26701 cacattgtct actcctgtca atacgatcag caaatccgca tcgatgattt cggctaattt
    26761 ttctgaagca aaatctttat cgattacggc ttctcgtcct tctaatccag tagctgtttc
    26821 tacaacagga atcccaccgc caccaacaga gactgtgata actccttgat cgaccagcgt
    26881 ttcgatgaca cgtgcttctt taatcgagat gggtttaggg gaagcgacta cttttctcca
    26941 tccacgtcca gcatcttctt tgaatgtcac agtggagtca gcattcattt gttctttggc
    27001 ttcttcttcc gtgtagaatg gaccgactgg tttacttgga tttttgaatg aaggatcatt
    27061 ttcatccaca ataacttgag tgactaaaga aaccacatct ttatcgatcc ctttttcctt
    27121 cagtacttcg cccatggcat tttgtaacca gtaaccgata gatccttctg tcattgcaac
    27181 acatgtatct aaaggcattg ccggtgtttt ctcagaatca gcagcttgct gctgaatcaa
    27241 taggttaccg acttgcggac catttccgtg ggagatgatc aattcatctc cttgttcgat
    27301 aaatttcact aaatactttg ctgtttccat taacgcttct tgttgggctt ttgcacttgc
    27361 atccgtagac aagattgcat taccccctaa agcgacaact acttttcgtt tggccatttc
    27421 attcgtcctt tcttcagttc taccgaattt tctagataac aaaacgagcc agcgttttgt
    27481 gattttccct caatgctgac tcgttttttc gtgagatgaa tgtggttatg cttaaacgcg
    27541 agggataaac aagttaccta atgttgctgc catgatcgct ttgattgagt gcatacgatt
    27601 ttctgcttgg tcaaattgac gagcatattt gctgcggaag acttcatctg ttacttccat
    27661 ttcagtgatg ccaaagcgtt ctttcatttg ttcaccgtaa acagtgtttg tatcatggaa
    27721 agctggcaag cagtgcaaga agatcaaacg atctgtgttg tgtgtttttt ctaccatttc
    27781 catattgatt tggtaaggtt tcaacaattt gatacgttct tcgaatttat cttcttcacc
    27841 cattgatacc catacatcag aataaaggac gtctgctccg tctacacctt tatcaacatc
    27901 gtcggtaatc atcaattgtg caccggattt ttcagcaaag ccttctgcca ttttgacgat
    27961 ttcttcttca ggttgtaatt cttttggtgc aacgatacgc atattcgctc ctaaaattgc
    28021 acctgtgact aataaagagt tagccatatt gtttcgacca tctccgcagt aagcaacagt
    28081 gataccttct actgttccaa agttttcttg gatagttaaa aagtcagcga tcatttgtgt
    28141 tggatgccat tcatcagtca agccattcca aactggaaca ccagagaatt ctgctagttc
    28201 ctctaccatt ttttgactga atccacggaa ttcgattcca tcaaacatac gacctagtac
    28261 tttagctgta tcttctgtgg attctttttt acctaattgg atatcatttg cacctagata
    28321 ttcaggatgt gcacctagat cgatcgctgc agtagtaaat gcagaacgag tacgtgtaga
    28381 tgttttttca aataaaagcg caatattttt tccttctaga tagtgatgtg ggataccacg
    28441 ttttttcaag tctttcaagt gttctgaaaa atcgatcaaa tattgtaatt cttcttttgt
    28501 aaagtctttt tctgctaata agcttcttcc ttggaatact gattctttca tattaaacat
    28561 tctcctttag attgttttta tttaagatta aagaggaaat cccgacggca gctgacagta
    28621 agaccgccgt caggaaacaa attacttcaa gtcttcacgg acaagtggtt ggctcatgca
    28681 gcgtggacca ccacggcctc gtgacaattc acttgaattg atttctaaca ctttgatgcc
    28741 atagctacga agcaattcgt tcgatacata atttcggtta taagtgacta caacacctgg
    28801 agcgattgcc aatgtgtttg atccatcatt ccattgttct cgaggtgcaa cgatctcatc
    28861 tccattacca gttgggatca gtacaagatc atctaatcca agagcagctt tcatcgtttc
    28921 gtgtaagtta tctgaatgag taatcttgat atcatcacca tctggttcga ttgtaaagac
    28981 atccatctta ccgtctttac tttgaattgc tggatggata gtgaatttat cgtgatctac
    29041 cattgtaaat acggtatcca aatgcatcat tgcacggttg tttggaattt tgattgctaa
    29101 cactttttca aatcctgaat tttttgcgaa taggtggcgt gctaattttt ctaaagcttt
    29161 cgcattagtt cgttgagaaa tcccaacagc tactacttta tcgcttaaga tcaattcgtc
    29221 tccgccttcg atatgatctg gattttcacg atccaaccat acttcgattc ctttatttgc
    29281 aaatcttgga tgatgtttca aaatatattc tgtaaacatc gattcacgac gacgtgcttc
    29341 aaaagtcatc ttattgactg tcatcccatt tcccattgat gcggaagggt cgcgtgtaaa
    29401 gtacaagttt ggcattgggt ccatgtaaaa tggatagtca tcgtctgctg acagatcgta
    29461 tagactgcta gaacgtactt caatatcttt tgtacgaacc ccagccatga ttttatctac
    29521 catttcttgc gtttccattg atagaaggaa ctcatgaaga ccctctctta cagcattcga
    29581 tgcaatatga gattcatcca acattttatt caagaattgt tctttgacat tgcctgcgtc
    29641 aatcgcttct gccgctaatt tttccaagta aagagtctcg acgccttcat tttgcaatgt
    29701 ctttgcaaag ttgtcatgtt cttcttgagc aatcggaaga tatggaatat catcgaacaa
    29761 cagacgatcc ataatatctg gtgtcaaatt ttccacttct tgtccaggcc ttttcagtaa
    29821 aactgtcttt aatttcccta tttcagagaa aacgtgaata ggtttatcca tgttgtgttg
    29881 cctccttctt tttgattaca tgtataggat atcctccttt tgtaatcact ttcataattt
    29941 tgtctcattc aaaatgagac attcctcaca ttaatattcg ataattaaat aattaaacgt
    30001 ttttctattt ttaagcgtaa tttattcatt ttttattctg tatacacttt caaaaaaata
    30061 tttattcatt gaaaaaaatt ttttgaataa attaaaaaaa taaattatat tagcgttgtt
    30121 agcgtttact atatgtatta ttgttgtttt ttatacacaa atcattcgct tcaaaacaaa
    30181 ttattcaata ccattgtata ttttttacat aataacaaat tatatttgta aagtattaaa
    30241 acttgtttct aatgttggta tgttaaaact ttacaaattc tttaaaaaaa gtgacaataa
    30301 atatagtgaa caataaggag aggacttttt aatgcgtgtt aataaaatcg attttcactt
    30361 ttcaaaactc agatatcaac ctgattttga acatttctcg gatgaagagt tccaacagat
    30421 caaggaacat actgttcttc gttcttataa aaaaggacag atccttttcg acgatggtga
    30481 tcccagacaa cggttgtata tcttgaccaa aggactcgtt cgtttagaac gttatgatga
    30541 aagtgcaact tattactact atgactatgt gaatacaaat aacctttttc ctatgtcagg
    30601 aatgtttgga gaagagacct acacttatac agctcaagcg atgactgata ttgaaacatt
    30661 ctaccttcct gtttcctact atgaaaaatt agcacgaaaa aatcccgaac agttgatcta
    30721 tatgatacaa aaaatttcta aagtagttga aatacatgaa ttgcgtatcc aaatcggatt
    30781 gacctctagc gcctttgacc gggtaaaaca aaatttattc attttgaaag aagaattggg
    30841 cgtaccaaca aaagatggtc atatcaccat tccttatccg atcaccttaa aagaattagc
    30901 agtgaatagc ggcacgacac gtgaaactgc tggacaagta atcaaacaac tacgtgattc
    30961 cggactgtta gattatgaca aaaagcgttt tactttctgt aagacagcta ctactccagc
    31021 tatgagagaa taacgcgaac aaaaataagc agtgaccctg atatttatca gggtcactgc
    31081 ttattttcct ccctaaaact tctgaaagat ccggcagttt tagatcactg ggcaagactc
    31141 aaagattttc tatgtgtgtt tcagttatgt aatattcact gtttgcaaaa aatactgata
    31201 gattaactag aggaagcgtc ttgtcctcat ccgacctaga ttattcgata ttcctcgaca
    31261 ataaacgatt aatcagtgag ggcaatcaga ggaacggata atgatgaata agctgtaaaa
    31321 aatagggctt tgacaaaagc gtgtcacagc ccttatttcg attaaacggt gtgtacctgt
    31381 caactcttcg gtcacaagtc ataatgttca taaacatgag gagctgtttt ttgaaattgt
    31441 tccttgtgaa tcagagttaa acgacaggct tacgaactct tgattaaacg gcgttcaaaa
    31501 gcttgcatac gcggtaataa gaacagccag gtcaaaaaca tgagaagccg tttttcctgg
    31561 gctgttctta ttacttgatg cagggcagat ttttcacaac ctctttattc agataaaacc
    31621 aagcttggat cagcattcaa ctgatagcta gcaaaatttc ttttttgcat ttccacatgt
    31681 gctgctgctc caatcattgc agcattatct ccacaaagtc gaagaggggg aatcactagt
    31741 tctacctcag ggagtttagt tgccaaagca tcctgcaatc cttcacgcaa cccttgattg
    31801 gccgctacac ctccagctac aatcagttgc ttgactggat aattttgaca agctcgaagt
    31861 gttttagtaa tcaatacatc gatcacactt gcttgaaagc tagctgctaa atcatttttg
    31921 tctagatctt ctccacgctg ttgtgcatta tgcaccaaat tgataaatgc actttttaat
    31981 ccgctaaaac tgaaatcata attatcttca tggatcatcg ctcgtggaaa atggtaatta
    32041 tcttttccct gatgagctag ctgatcgatt tcttttccgc ttgggtaaga aagacctaat
    32101 actcttccaa ctttgtcata agcttctcct gctgcgtcat ctcttgtctc cccaatgatt
    32161 tcatatgatc catcttcttg catatagact aattctgtat gtcctccgct aacaagaagt
    32221 gccatcaatg gaaactggaa tggtttaacc agacgggctg catagatatg ccctgccata
    32281 tggtttacag gaataagcgg caattggtgt gcccaagcaa aagccttagc tgcagaaata
    32341 ccaatcagca acgagccgac aagtcctggt ccataagtga cagcgactgc cgataaatct
    32401 tctgccgaca caccagcttc taccagtgca tcttccaagc ataaggtgat ttgttctacg
    32461 tgatggcggc tagctacttc aggaactacg ccaccaaaac gtttatgact gtttatttga
    32521 gaagcaacga tgttagataa gatctctgtt ccatttctaa cgaccgctac actcgtttca
    32581 tcacaacttg attcaatcgc cagaatcaat tcttcattca tttcatcgtc tccgttttta
    32641 actttctgct cataatgatc gcatcttccg tcggattgcg ataatatgat ttccgtttac
    32701 ctaatatacg aaacttttct gattcataaa gttttcttgc tgcttcatta gatagacgta
    32761 cttctaaaaa aacatgcagc gaatctttta tttgttccgt aatcagtaat tgtaacaaat
    32821 gccgtgcatg cccttttcct tgttctgaaa ctgcaacagc aatatttgtg atctcgactt
    32881 catctattac tttcgagtat ccaataaagc cacagatctg gttatcttca actaaaagca
    32941 gataatcaga gtgaggctgt tggatgtctg ccaaaaactg cattttcgtc caaggtgaac
    33001 catgtggata agcattttcg ctaatcatcc atacgcattc tgccaagtac gcttcatcaa
    33061 aatctttttt tctgcaaatc aactaatctc actcattttc taaaagtttt atcatatcca
    33121 acgcatcttc ttttgtttca gtgtaatatc tttttttgat cgttgttgct tgaaaaccta
    33181 acttccgata aagtctttgt gcatcttgat tactcatacg cacttctaat gacatcgtct
    33241 cacagcgatt cattatagca aagttctcga tttcgtcaat aagcagcgaa ccgattcgtt
    33301 tacgctgata tgccggtcga acggcaatat tcgtgatatg gcaatctaaa ccgaacgctc
    33361 ttgaaccgat aaaaccaatc attcttccat tatcaaagat acctagatat agatgaggaa
    33421 gcggtgactt caattctgat ataaaggcac tttttgtcca tggcaattcg ccattataga
    33481 cttctcgttc gacatccagc agctctttga tatcttctgt agtcaattct cttagtacgt
    33541 aacgacgatc gatttgttcg attgtttttt ctgtataaat cattttatct tgaaaaaagc
    33601 ttctggcata cgctctaaat tttttcaaca taactttcgt ctccaggtgt gtgcgtctcc
    33661 aaccattttt cttctgcttc tacccgtttt aaatagcgag gaagaaaagc ttgtttctct
    33721 gcaactggtt cagctaaagc acctaattga gccacagtta caccacttgg aatatcccat
    33781 gctggaactg tattaatcat cgcactaggc aatatttcct ttatttcata gaagaatttg
    33841 tgacaatcac tcccgacgaa ataaatagct tcattcagct tttgtagttg tgtgaacaaa
    33901 tcagaagcag aaatatgtac atcttcaagt acaatttcta atctattttc tttccagcgg
    33961 tatgccccag cgtatacatt ttttcttcga gcatcaaaca tgggcacaat aattttatcc
    34021 acaccgatgc aattagccgc gatggttttc agactagata ctcctactag ctctttatct
    34081 aatgtataag caatcgtttt tgctgtcgtt acacctatac gaagccctgt ataagaaccg
    34141 ggaccatcag aaaccgcgat tcggtcaatg tcttttggac ttatttgaag atctgcaaac
    34201 aattggtcga ttgcaggcat cagtgttaca ctgtggttgc gtttgatatt tgtttgtatt
    34261 tgtccaagaa tttgttcgtc ttctaccaca ccgatcgcca aagtttggtt tgcagtatct
    34321 attcctaatg taatcatata tttgatcctt tctgctatga cattctcgcc ttccattgta
    34381 gcatactttt ttattctgag gatgaaaata ccaaaggcaa aactagtaca atgatacatg
    34441 attatctgct ggcgggcaaa ttttgcccct tcctgaaaca caaaaaagct gcggtatcac
    34501 ttcatttccc cacagctttt ccatctttta tttcgttgat tctcgaataa tcaactctgt
    34561 ttccacaata atctttcttg aaaccggtgc tttggaatta cttaattgaa gaatcgtctc
    34621 cactgctagc tctcccatcc attcggtata aacttttaca gtagaaagag agggcgttac
    34681 atatttcgct acactgacat cattgaaacc catcacagaa atatcttctg gtaccactaa
    34741 acctttttct tgaatcgctt tcagtgcgcc aatcgctaat gcatcattag ctgcaaaaag
    34801 cgcatcagga acatgcggat tcgtttttaa atactgcttc actgcttgat atcctgactc
    34861 gacagaaaaa tctgcttcga taattggacc ttcgtcgtag cctttttctg ccaaaacttg
    34921 ttgaaatgcc ataattctgg gatcttttag ccgctgatgg tttttcttcg tatattctgt
    34981 tccagcaagc atagcgatat gttgcgcttt atgggagaca aaatgttcaa tgactttttg
    35041 aacacttgac ttaaagtcga caactagaga gtcgattcct tgagaagtgc cgtcagaatc
    35101 taccaaaagc aaggcatttt gggatccttt catttctaat aactgagctt cgtcgaattt
    35161 tcctagtgcg atcgttccat ctgtcggaag atcactaatg gaatcccacg tttctttcaa
    35221 taaagtaacg tttgcttctt ctgccttttt ttcgattcct agacgaatag ataaataata
    35281 aagatcttca agctcttccg tatcgtcgta ccactggatc aggcgaagcg tttgcttagt
    35341 atttgctgca tttttacgat gtttcgtata atttaagcgt tctgctgctt caaaaatttt
    35401 ttgctttgtg gctaagccaa cggaaagatc aggatcatag ttgagaactc ttgaaacagt
    35461 agcaggagaa actcctgcca actgcgcaat gtctttaatt gttgccattt gtctctcctc
    35521 cttttttacg tttataaaat tgcagtaaat cgttcaaacg ctgcctgtcc tttttcatct
    35581 cgcttgaata ctccagcgtc ttccagtaca cgtgcaaaaa cctgacctac agatttttgt
    35641 acgacatcgg tgaccgtatc tttcgtcaaa tcaggatgtt ctttttttaa ttgttctgcc
    35701 cacggacgat gatattcagc catctggttt tcttctccta ataagaaatg ctctacttct
    35761 actagttctg gtttcaaacg aggtggtaaa acagcaagcc ccattacttc gatcaaccca
    35821 atgttctcct ttttgatatg ttggacatct ttatgtggat gaaaaatccc atcaggatgt
    35881 tcttctgaaa cattgttgtc tcgaaggaca aggtccaact caaagtaatt gtcccttctt
    35941 cgtgcaattg gcgtaatcgt atggtgtggt gtaccatctg ctgaaaaagc tctgatagat
    36001 actgtttcat ccgaatatgc tttccacttt tccaatactg agttagctgc ttcaatcaac
    36061 aattttttct ctgctgattg caaacggatc acagacatcg gccatttcac gactcctgcg
    36121 atgacttgcg gataatctgc tagtttgata agtttttcta tcggtgcttt tgccatagga
    36181 aattcatgac gtcctgcctg ataatgatca tgagaaagaa tcgatcctcc aacaatcggc
    36241 aagtcagcat tcgaaccaac aaagtaatga ggcaagactt cagtaatccg aagcagtcta
    36301 gcaaatgttt cctttgtgat tttcatcggg cggtgttgtt ctgataaaat gatcgaatgt
    36361 tcattgtaat aagcataagg agaatattgg aatccccagc tttcaccgtc tagattcatt
    36421 cgaataatcc ggtgattggt gcgggctgga tagttcaagc gacctctata tccttcgttt
    36481 tccatgcaaa gcatgcaggt aggatagtct acttttaccg cctcgcgttc tgctgcgatt
    36541 tgttttggat ctttttctgg cttagataaa ttgattgtga tttccagttc accatactcc
    36601 gactctgccg gaaatttgat gttttttgcg atggctcttg ttttgatgta gtcatttttc
    36661 ttacttaaat taaagaaata ctcagttgct tcctctgggc ttttcgaata gtgctgtgca
    36721 aagaatgcat tgacgactga aggtggcggt gtgagaaaat ccattaattg cgcttcaaaa
    36781 atctcttgtt ctgctggcaa ttctgaaaga acaccatttt ctcttgcctt agcgacaagc
    36841 tgatccaata agtctacaga ttcttcctta actggtctta cttcaatgct ttctagagca
    36901 tcttctccta ccatccctaa aagacgattc tgtaaatata agcggtccat ttccatccat
    36961 ccgccagctt cgatcgcaag tgtggcaaaa tcacaaatcg tttgactgat tgacatatct
    37021 cattccccta ttcttcataa ccatttggat ggctgacatg ccaatcccat gctgttttga
    37081 taattgcttt gatatctgtg tattcaggtt tccaacccag aacctctctc gctttttcac
    37141 ttgaagcgac taatcggcta ggatctccag ctcttcttgg tgctatttct gctggaattt
    37201 cttttcctgt cacttctcta gctgcttcta gcatttcctt gactgagtat cctttgctgc
    37261 tgcctaaatt gaagaagttg ctttcatttc cttctttcaa gtattccaaa gctaaaatat
    37321 gtgcagcaat caaatcttct acttgaacat aatctctgat acatgttcca tctggtgtat
    37381 cataatcgtc tccataaaca gccaatgctt ttctttgacc aagagctact tgtaaaatga
    37441 ttgggacaag atgcgtttct ggtgtatgat cttctccgat agatgcatct gcttttgctc
    37501 cggctacatt gaagtagcgc aaagcgacat agcgcatgcc atatgcttgg tcacaccact
    37561 tcatcatttt ttccatcatc aatttacttt caccatacgg atttttagga ttagctggtg
    37621 tatcttctgt gattggagac tcttttggtt ctccgtaagt tgctgcagta gaagagaaca
    37681 cgattttatt cacattgaac tcgtgcatga cttcaagtaa gatttgcata ccgtatacgt
    37741 tgttgttgaa atacatcaat ggtttttcga cagattctcc tactaaagag cttgcagcaa
    37801 aatggattac tccttcaatc ggttcctttt caaatacgga acgtagaaat tctttatccc
    37861 ggatgtctcc ttcataaaaa tgagcatctg gatgtactgc ttgtttgtga cctgtgagca
    37921 aattatctac cacagctact tgatacccct tttgaactag ctggtctaca gcgtgcgaac
    37981 cgatataacc ggctccgcct agtactaaaa ttgtcataaa aaacactcct ttgattagta
    38041 aaattgtgtt tgttgattat atataattta aaaaaacgaa gtttactttt atggtgaaaa
    38101 caaacaaagt aaaatttcgt aaattcatat ggtaaattta taataaaaca tttagtaaac
    38161 attttcaagg attttttgca aaggtttaca aacaaacgta aaactagcct ttttttctct
    38221 tttgttccat aatagatata acaaataata aatgaggtgg attcaatgaa aaaatttgta
    38281 tctggaatat tagtaggaag tctggcaaca gccgctgccg ttgctggttt ggtcgcttct
    38341 gtgaaaaaaa cagtgatcga tccaattgac gaaaaagaag caatgatcga agaaaaccgt
    38401 aaaaaagcaa tgcgcaaacg cgtttctcgt taataattat ttaaaaacac gcatgaagac
    38461 ttgtgaaaga acagataagt catcatgcgt atttttattt gtcagtcaat ataagttgtg
    38521 ctattttatc tgcctgtctc agattccatg gatctgtata aggtctagct actgctgcag
    38581 ttagccaatc cacaccttca acaggtattc catagcaata aaagtcagac tggatttccc
    38641 ctgaagcatc aatcacgcga ttcgtacctc gctcaacatc tatagcttct gaatgataac
    38701 ttcctgtatt atctgaaaat gaaaaagggc gaacaagttt gttttccttc aaatttttta
    38761 tgacaggatt acttgaacga gaaaagcttg tttgtggcaa tcgagcttca atcaaatagc
    38821 gactgctgat ttctttatct tgtagagaaa taacatagcg gttgtgcttt tgctgaatat
    38881 caaatggcgg ttcgaacaaa tgaaaaatac ccgcatctat cagtgctgct aattctttcg
    38941 tccgaatgac tggcggaccg atcgttaaaa agctatttag atgagtaaac catccccata
    39001 gtatttcttt gtattccttt gcagaaaaaa cgtgccattc aatagcctgc cggattggat
    39061 cacgccagtc ttttaatgca tcaaatgttg aagcaaatgc tcctgtgcaa ttgccttttt
    39121 ccgcttcttt tatctgccct tcaataaatg ctcggctagc ttctgcaaag gactcatcct
    39181 gataggtaag aggaatttct aaatacgacc aatcccatct ataagggatt agtgctggat
    39241 gctttccgag acactcctct gaagagaggg agagaaaatc atgctcaaaa tttttctttg
    39301 gaatcggcaa atgatattct tcgatgattt tcttgtaata aaacaactca acgtcttttt
    39361 tcagatagtc aaaaaatgtt tcgccagtca aaaatcccga ctgatgccat tgctccaggt
    39421 tttcttttgt tagtaaccgt ggccatgcca ttgatccgcc ttgcttttgg tttcttcctc
    39481 gagggtaata agggagcccc cttcttgatc cactgtatac aatcggttcc ttgcctgatg
    39541 gatgatagac aagttttcct ttttcgttct cgaagcgccc ttctcttgat actgtaaaca
    39601 atccgacata atcaaaaaaa cttaagccta gacctcttaa aaagacattt tctttaggcg
    39661 gtatcttcga aagatcgaca tctgcaggat tagaaggaag ctgatacagt aaatcatttt
    39721 tctttgcgta gtctacccac actctttctt cttctgtctc atcattttcc cagtgaccgc
    39781 ttgctaaaac aagctgatcg atagaatagc tttgctgatc tgtctgtaaa agataaccat
    39841 cttttctttt gctgactttt tttactaaag aataaacaaa ctgaatagaa gctggaaatt
    39901 cttcttgcaa ctttgagaaa aaccagcgtt gatagagtcc gtataaacat cgagtagatt
    39961 gctgatcttt ttccagacga ttgatttctt ctataattag ttgcttattt ttggttaccg
    40021 tctgttcgat ataatctgta gcaggtcctt tactccattg aaacaagttg ggtccctgtg
    40081 ttaccaatcc tccactggac aatgtttcat ctgtaaaaag cgtcacttgt tgagaaacag
    40141 aattcattaa taactccggt ggctgattca accgccaaac tcgacctcca ggaccattgg
    40201 gatcgaaaag aaaaagttca agagaatgtc tgtcctgatt attatggaga atcctttctg
    40261 ctatacttaa tcctctaggt ccggcaccaa tgatccctat tttcatttgc atgcctccat
    40321 ttcgataaat tttttcaata aaacagcatg gttctgatgt tcattttttg caccataaac
    40381 aaaagtaatg actggatgtt ctttcataag ttgactgagt ttaaaaatag cttgcttctt
    40441 ttcttcttcg aaaatcaatt cttgctggta tttctttgca aatgaagcaa atcgttctgg
    40501 tacatggtca aaagttttgc gtgcttcatt actaggtgca atttctttca accacagatc
    40561 taactgcgct ttttcttttg aaattcctcg tggccagaac ctatccacga gtattctata
    40621 gccatcctct ttttcagcat caaggtaaac acgttttaat ttgatcatag ttgtttcctt
    40681 ctttctgcct tttcgcttag cttatatatg tagataatag cacaaaataa aaaaaatgaa
    40741 cggcacaact atccattgcg ccgttcatgt gatcttggtc aaaatctaat gattgattcg
    40801 gtttttaaag ctgtcataca atcatctgtt ttatactttt ttacttttga tttttccaga
    40861 ccatccgtca tatccaccct taagtaaata aatctcttga taacctgctt tacgtaattt
    40921 atttgctgta cggatgctca agcttttctt ttgatcgtaa atatagacag gctggtcttt
    40981 tcgaatagat cctaatgaat ctttcaaaac agtgtaaggg atgtttcttg cacctaaaat
    41041 atgcccagca tcaaacacat ctttttcgcg aacatcgatt acttgtgctt ttctcattcc
    41101 ttctcgaaat tcttcttctg tcaaagtcgt tgctgaacgc ttggccatta ctcgtagata
    41161 gacttcccaa aagatgattg caagcacaat caatagcaaa atgatattaa ttacccataa
    41221 aaccatgtaa tgcctccgtt tttttaagca aatttcaagg ctaatgaggc agcaccaatg
    41281 acaccagctt cattaccaag ctctgctaat ttgatttttg ttgattctct tacttgcggg
    41341 aaagtaaatt ctttaaaata tttctctaca cggctacgta aaaattctcc tgctgccgat
    41401 actcctccac ctaacacaat acttgacgga ttcaatgtat tccccaagtt ggcgcaagct
    41461 aaacctaagt agaagcatac gcgatcaaca accatcaatg caaacggatc gtcttcttga
    41521 gccatttcaa agatatcttt acttgttact tcttcaccgt tgtctaacat tgctttcagt
    41581 tttgaatctc ctgcgtattc ttctgccaag taacgaccta gacgtaccac accagtagcg
    41641 ctagacacag tttctaaaca tccgcgttta ccgcaagtac attcgaaccc ttcaggatcc
    41701 acagtgatat ggccgatctc tccgcctgct ccgctcacgc cgtgaatcaa atttccgcca
    41761 gcaacgatac caccgccaac acctgttcct agagtaacga atacaacgtc tggatcgttt
    41821 tctccagcac ctttccatcg ttcacctaaa gcagcaacat tcgcatcatt atcgatagcg
    41881 aatttgattc ctgttcctgc ctcgatcagt tttttcacaa attgaacttc tgtccagttt
    41941 aagttatacg caccaataac cgttccagct tcgctgtcca cgcttcctgg ggtacccatg
    42001 ccgattccga taaagtcttc ggctttcata ttatataaat tcaaacgatg gttgattgat
    42061 tcaatgattt caggaacgat atgcttacca tcatccaaaa tattggtatc gatgctccat
    42121 ttttgttgaa tctctccttc tggtgttaaa attgcaaatt ttgctgttgt tccacctaaa
    42181 tcaatcccaa taatcttctt gtccattaca aatttccttt ctttcggctt tcttcaattc
    42241 ggtgctctct ttttaatatg cgccacgctg tcatgtatgt atcatgatca atcaaacggc
    42301 tatcatacag attacgcaat tcgatagtca ttaattcaat gtcatagatg cgtgcaccca
    42361 catagataaa gatgccaaat tttttgaaca gctgctgtac atcatataag ctctccatct
    42421 ttaagcactt ccttcatatt atacaagtaa accatatttt tttaaaccca gtaaaataca
    42481 tattacaaaa agaaatacaa aaactagtgt agaaagaatc ctttggtgta tcgaatagct
    42541 tgtctgttgt ttcggtagac ccaaaacatt ccctaacact aatccgccaa ttagcccacc
    42601 gacatgtccc caaacatcta cagaggtatc cagaagacca aaaacaaatg tcaacacaat
    42661 aaataaaaga aaatgtctga ctagctgctg gatcgctggg ttatgtttaa aatgaaaccc
    42721 taagataaac aacgcaccga acaaaccgaa tatcgaagta ctcgcaccac cagacagaac
    42781 attcgcttcg ttaaaagcaa agcttgctgt atttcccatt atcccgctga acatataaat
    42841 caagaaaaaa cgccaatggc catagattgc ctcgatttgc tgccccataa aatacagtat
    42901 cagtgagttc attacgaaat gcatcagtcc aaaatggatg aagattggtg tcactaaacg
    42961 ccaccattca ttgaagtgaa caagataagg accatacatt ccggcataat aagggatctc
    43021 aagtcgcgga aataattcca tcatgaggaa gaccgctgtc tgtatcccta aaaaagcata
    43081 ggtccataac ggtcgtctta accatgcacg caattttatt tgctgttgat aattcatgaa
    43141 aacctcccat ttcattttag tcaataaaca attgttggat cttctgatca aagctctccg
    43201 gttgccattg ttcattcaat tgttcacgaa aaacaaggct acatgttttt ttatgaaaat
    43261 tatttaaata ccggtcgtaa taaccaccgc caaaaccgat tcgataaccg gctctattgt
    43321 agataatacc tggtacaatg aggagatcga tcatctccgg caaatagagc ttctctgatt
    43381 gtggctcaag aacaccaaaa ctcgaacgta caagaacgga ctgttcatcc atttcataaa
    43441 acgccatctg acgtttcggc aaagttttag gtacaactat tttcttttgt tctttttctg
    43501 ctcgttggat aaccggctgt gtatccagtt caaattcatt cgataaagtc gtccctatca
    43561 cttttgctga cttccagtac tcgctggcga atagctgttt atagattcgc tgttcttttt
    43621 cctttttctt gccacttttg gccagatttt tcagcttttc gattcctttc cggcgtaatc
    43681 ttactttcaa ttggtccaaa aactcaccct tccttctctc ataaaatggt ataggaaaaa
    43741 aagaaaaata gcaatcgaac tttcaaataa atgcataaat agaataaaaa gaagacctag
    43801 aaatgattgg ccttcctttt ttaataaatt tcaactgttc agcgcgtgtt tttgtctgat
    43861 aaaaagtgca tacagaaaat atggcgcacc aaaaagggca atcaaaattc ctgtaggtac
    43921 ttccccactt ggtagaatca ctctagcaac catatctgca ctaagcagaa aaatggaacc
    43981 gaacaaaccg ctcagaacaa aggtccagtt attttcttta cgtacgacta gcttcgcagc
    44041 atgaggagct agtagtccta caaaagataa actacctgtc accgctacac taccgcttgc
    44101 caaagcaaca gctaacaaca aaaggatttt ttgactttta gccacgttaa ggcctaatcc
    44161 ttgcgcgcgt tcttgaccaa atgatagcaa tccaatcctc tgtgcataaa gtcctcctag
    44221 cggaattaag ataaccgccc atggaagcaa tgcccaaaca taaggccagc tcgcacccca
    44281 gattgatccc gctaaccatg cattcacaaa tccataattt tccttagata attggatcgt
    44341 gcatagcaat gttaatgcag aaaggccggc attaacggca ataccggaca ataagattcg
    44401 attcataccc aaaaagccat ttcgatcata ggccgcaaga tagacacagc aagcagctaa
    44461 aacaccacct agaaaggcta caactagcaa tagaaacggc agcgaatagt gcgaaaagaa
    44521 acctaaataa agcatcacta aaaatcctgc tccggcatta atgcccaata tactagaatc
    44581 tgccaattca tttcttgtta ctccttgcaa gatataacca gaaacgccaa gacaagctcc
    44641 tgctaataaa ctgatcagta atcgaggaac tcgaaattct ctaacaatca gcgccaaaga
    44701 agatgattct ttccctatga acgtggcaaa aagctgatcc aggtaaataa aaggcgtacc
    44761 aatcattaaa ctacctatag acaggatgac aagtacaaaa agcaagaaat agaacgtcca
    44821 atatattttt ttcaccgttg ttccctcctt acttgtatca gtaaaaacgg aacgccaatc
    44881 aatgcaatga ctaatccaaa aggtgtttca aaagggggat tgatcatcct cgctgtaaaa
    44941 tccgccaaca taaccaatcc accgccaact aaaaaagaga caggtagaac ataacgatag
    45001 tccgttccaa ccattccgcg aacaactggc ggaaccaaca gcccaataaa tgaaacaggt
    45061 ccgactaacg aaacggcaat ggctgctaac actgcaacta gacagaaaac aatcaaccgc
    45121 gttcgtttag gatgacttcc aagagctaat gcatgtgttt cactcaaatg aatcaaagat
    45181 attgcttttc ctaatgaaaa agaaaccaaa acagcaagta tatataaagg aaacaatact
    45241 gctaattgtt tccatgtgat attggcagct ccgcctacaa accaaaaagc aagatcctgc
    45301 tgcagattaa agaattgggt aagtgcttgg ctgatagcag taaaaaaaga actaatagct
    45361 acgccagcta aaatcagctg taaaggattc atgcccattt tcgaaaactg caaaaaacca
    45421 aatacgagca aagttacagc aaaagaacct gccaatgaca ttagaaacac agaaaaatca
    45481 gaagctttag gccaaaaagc aaaactaagg gccattgcca acgaagcacc cgcgttgatt
    45541 cctagtaagc ctgaatctgc taaaggattt cttgtcactc cttgcatcaa tgcaccgctc
    45601 aatgcaaaac aactccctac aagaaatgct cccgccacac gaggcaaacg aatatttcgt
    45661 atgatttggt gactttgttt tgatctatca aaatcaaaca acgcctgcca aaaatctgct
    45721 tttcccacag tcgctgcgcc atttgaaaga gcaacaaaaa aaataatcaa aagaacaaaa
    45781 cagaccaaaa gcaggagtct atttttcttc atagtcctca taattgatcc tcctgctctt
    45841 ttggcaacaa atcataggtt agaaaaactg gtttatttgt tcttggaagc gtgacaatcg
    45901 ttgcatcaat ctcaaatatt tttttcatac actcttttgt gatcacttct tcaggtgtac
    45961 cttctgtgat caacttaccg tttttcattg ctaataaata atctgaaaaa cgtgaagcat
    46021 gattaatgtc atgaatcgac atcaagatcg ttgtttgttt catttgattg atttcagtca
    46081 ataactgtag gatctctaat tggtgtgccg gatctaaaaa tgttgtcggt tcatccaaga
    46141 tcaagatatc tgtttcctga gcaagcgcca tagcgatcca gacacgctgg gtttgtccac
    46201 cagacagcgt tgcgatatcc cgcatacgaa atccagctag acctgtagca tccaacgccc
    46261 actcgattgc ttcatgatct tgcgtgtcca tgccactgaa cagtttttga taagggtatc
    46321 gtccgtaaga tactacttct tctactgtca tacctgtagg gtgttcacta gtttgtgcta
    46381 ataatgtaat tttttttgca agttcttttg aactgtatgt agagatatca gagttattga
    46441 caatgatctt tcctgatttc acaggtagta tacgggtaaa acttttcaat aaagtagatt
    46501 ttccacttcc atttggccca atcaaactag tgattttccc ttcaggaatc gtaacagaca
    46561 tgttttcaat gatttttttg ttttcgtagc cggctgcaat gtcagctgct cttaatctcg
    46621 tcatttcacc catcctttcg ctgaaaatca ttctcaatta tgacgctgtt tcaacatttc
    46681 gtcaagcgct actttcatat ctatagccaa atgaagcggt tgacagcgtt cgaaatatca
    46741 ggaataataa ccaatgagaa agattctcaa ttatgttagg aggaaagaaa tgaaattaaa
    46801 aacaaaagta ttcacattat ctagcatatt gctgctggct ggagtactga gcgcttgctc
    46861 cccctcttca gataaagaaa cagctacaac tgccaattcg acgacttcat ccaatagtac
    46921 tcatacagtc acagatacac ttggacataa agtagagatt ccaaacgcgc ccaaacggat
    46981 catcggcagt tacttagaag actatctgat tgcactaggg gaaaaaccta tcgcccagtg
    47041 gactgttggc agtggttcca ttcaagatta tctgcaagat gatttaaagg atgtcccaac
    47101 gatttcttat gaccttcctt atgagaaagt gttaagcttt gagcctgatt tgctgttgat
    47161 ttcttcttcc gctactgtcg aaggcgggaa atacgaacaa tatagcaaaa tcgcgccaac
    47221 ttatgttgta aaaaacggaa cagatgtcac atgggaagaa caactaaaag atgtcggcaa
    47281 agctttggca aaagaaaaag aggcagaaaa aatcatttcc gattatcaaa aatccatcaa
    47341 gaaaactcga gaagaactag cagataaaat cgagaacaag acagctgcag tgttgtgggt
    47401 gaccaacaac tcagccttta tggtcagcaa aaatcggtca agtggaagaa tcgtatacga
    47461 cgatctggaa tttggtgttc ctgatctagt ggaagaggtc tccaaaaaag ccacttctga
    47521 ctggtctgct gtttcctctg aaaagctagc tgaattagat gctgactaca tcatccttgt
    47581 gaacagtgac aaagatgctg ccatgttcaa tgaaccaagc tggaagaatc ttaaagcagt
    47641 gacagacaat catgtactgc aattcggacc tgaatctagt tggctatata acggacctat
    47701 tgccagtcag gaaatggtca atgatatcaa agaaaaacta aattgatttt aactaaaaaa
    47761 agcatcttca cgattagtcg tgagatgctt tttttcttat taacaaacta gacgcataga
    47821 ttttattctt cttttgaagc aaccctattt tttactcttt cccatttttg aaaacgatgg
    47881 gcatatagat tttcttgatc cgttatcccc tcatactcct ctataagggc gaagtctgaa
    47941 aaatcaatat tcccaatata cgtatcgcct tcaaacgtgc tatcgatcaa tgttcgccag
    48001 atccgaccag tgtaaggaag aagttcttga aaaatccgac taccacccga aacatagata
    48061 tcttctgaga tcgtttgact atacgacaaa agttcatcga tcgaatgcat tacttccgca
    48121 ttttctttcg tgcgaaaatt tggttgcgtt gtcaacacga tgatatggcg ataaggaagt
    48181 gaaagatccc ccattccttc ataggtcttt cttcccatca ctaaaattcg atccattgta
    48241 tgttcgcgaa agaaacgcat atcatttggc aatcgccatg gtaacaaacc atttttgccg
    48301 atcagaccat ttttatcttg tgcccacatg gaaataaaca tattatccgc tccttatgat
    48361 tttagatgtt ttgagataaa aaaagtctca attctttgac cagcaaggaa ttgagaactt
    48421 taaaaacatt attttgtttc acggtgcaaa gtaactttgc gttcgcgtgg gcaatatttt
    48481 tgtttttcca aacgatcagg attgttacgt ttgtttttgc ttgttagata gttacgttct
    48541 ttacaagaag tacactctaa agtgatgttt acgcgcatgt ttttccctcc catttttaca
    48601 agaatcctct aagatgactc tcagacttga ttatcttacc atgatttttt ctagattgct
    48661 agtgtttttc acgattttgt taagtaaaac tacttgacga taaatacaac ggttttactt
    48721 ctcaaacaaa atctttttct ttttgtataa atacccttac acttgtttat atagattatg
    48781 ttttttaata aagggggata ctaatatgcc atggaacatg aaggactttc ctgcatcaat
    48841 gaaaaactta gataaattga caagaaaaaa agcaatcgac atcgcaaatg cattattaga
    48901 tgaagggtac cctgataacc gtgcgatccc aattgccatt gatcaagcaa aaaaatggta
    48961 tgaagatgct agtgaatcag aaaaacgaac tttcgaaaaa gaaaaaaatc caagcaagac
    49021 ggatgaacac gatacgaatc ctcgtgctgg aaaactgctt gattcagatg tgatcgtaga
    49081 atatgaggaa gaacaatgga tcgtgaaatc taaaggggca aaaaaggcaa gcaaccattt
    49141 tgatacaaaa aaagaagcaa tcgaaaaagg aaagcaagta gcacaaaaca aagaatcaac
    49201 tttgttcatt tataaaaaag atgggacaaa agaaaaagaa atcgattatt gaacatatgt
    49261 aaaggggttg tgacgaaaat cgtgtcacaa cccccttatg ttcgaaacaa tggtgttcct
    49321 ctgccaactc cgaaccataa gtcataatat ctataaaacg ggaagagctg ttttttgaaa
    49381 ttgtttctta tcactcagtg ttaaacggta ggagaaaacc tcttttttat tgatatttga
    49441 ttttcatcaa acagtcacat agtcgattgc ttctgcttgc ggaatcgttt catctacaaa
    49501 gtagacttta taccatgtca agaaactgaa gattgtccag atttttcttt gctcttcttt
    49561 acgtccttcg tgatggtcat ctagcaactt catgattttt tcttgatcaa aaaattcttt
    49621 tgcaaaatct gcttcgaata atgctttgac ttgttcgtag ccgtgttctt ctttcaacca
    49681 agctttgatt ggcacaggga atcctaattt cacacgattc gaccattctt ccggaagatg
    49741 tttgttcgca gcttgtctga aaatatcttt tgtgttgttt tgattcaata aaaacttact
    49801 tggtatttgt tgagccaatt tcatgacttc gatatccaat aaaggtactc ggacttccaa
    49861 agaacttgcc atagaaagtt tatctgcctt taacaagata tcttttggca tccattgatg
    49921 aagatcgaca tattgcatct tattgacttc atctttgatt ccttctgttt tctcgtaatg
    49981 aacagtcatg atttcatcca cagatggtgc tgtttgatat tttggtgtta acacttctga
    50041 tgcttctgat tcttcgaaca ctcgagcatg accgataaaa tattcttttg caggagcaag
    50101 tgattcatat aaatggatcc gtccatggaa atttttcatt tttccgattt tacgtcctaa
    50161 attatagcgt gttccttttg gtaatttttt caatccttga gcaatcacac ggatgaattt
    50221 tgaattcgta tggaatccat acgtttggta tcccgcaaac agttcatccg ccccttctcc
    50281 agattggact acccgcacac tttgtgaagc aagatttgct aaaaagtaca aaggtacgca
    50341 agaaggattt gaatcaggtt catctaagtg atactggatc aaagggaatg ctttgaacga
    50401 catgtctccg tcgatcactg ctgctgtatt atctaagtcc aatagttcgg ttagttttct
    50461 ggcttcaatc gcttcattat aggttttatc atcaaacccg attgagaaag aatgatctgg
    50521 tttcaataca gaggttacat aactggaatc aaccccgctg gataagaaag aaccaacttc
    50581 tacatcactg accgtatgtg cttcaataga agcttgaacg gtttcgtcga ttttttcgat
    50641 ccattcttgt cgggaatgcg tttcttttgt ttcaaaatct gcatcccaat attgctgaat
    50701 gtctagtttt ccatctttat acgtataata atggccttca ggcaaacgat agacatcttt
    50761 gaagaatgtt tcgccgttta atggagaata ttggaaagtc atataaggtt tcaacgcttc
    50821 tttgttcaat tctttgttaa aatcaggatg aggcagaaaa cttttgattt ctgaaccaaa
    50881 cataaatgtt ccgttcattt ctgcataata atatggtttg atcccaaagt ggtctcttgc
    50941 accgaataac tcattctttt cattatccca aatagcaaaa gcaaacattc cgcggatctt
    51001 ttgcaataat tctgttcccc attcttcgta accatgcaaa aggacttctg tatctgcatg
    51061 tgtttgaaaa acgtggccag ctgcaatcaa ttcttctctc aaaggctggt aattatagat
    51121 ttcgccatta aaaataatga tctttgtccg atcttcattg taaataggct gagtaccgcc
    51181 ctctaagtca ataatactta atcttctgaa tcctaaagca acatgtttat cgatatattc
    51241 tcctgaacta ttaggtccac ggtgaacgat tcgatccatc attgtattaa taattgtttt
    51301 tttgttgtcc ttgtcgttaa caaaacctac aataccgcac atttaacttt cacatcctaa
    51361 tataaaatta ctgtttattt cattcatatg catcttatca tagaataaat agcggacgaa
    51421 tattttctct cttacaattt cgtcacgtga aaacaaaaga tgaaagtttc tgtttttaca
    51481 gaaaataaag tcccaatatc taatttacca tgttttcttt tttgaggcta ccttattctc
    51541 ttcgtgttaa aaaaatatta gtggatgcta tttccaaaaa aaacagcaaa aaaagacacg
    51601 acctaaagat cgtgtctaat tatgactgta tcagaaaata tgataccaaa cggatctatt
    51661 cattaattaa ttgacatagt ttatctgttg ctcttttatg actggataac tgaccaattc
    51721 atgacgatcc aagtcttctt tatttatatt tacagcagta atttgactgt cttcatacgt
    51781 acgataataa taaatccctt tatcaacgtt acagcaagaa gaataaatcg tatattcgta
    51841 ttttccttct ccagtatcgc atactccttt ttgttgctcg actgagccta gtatatgaaa
    51901 aaattgactg atactttcag attctgaatc acctgatgca gcattcattt tagtaaatgt
    51961 ggcttttaca aatcgagaaa cagaagagag atctccaggt aagcccaatc ctcccatccc
    52021 acgactataa acattcaagc tgatctggtt tgaaaaatga ttttctggtg ttccatttga
    52081 tagcgagcga taattgttca gattaaataa ttgataatca aatggcggat tatttgtcaa
    52141 cacaccgaca ggattatcat ataaatgaag tccatctttc atactttcaa ttactatcga
    52201 tttttcttta tcagctaata accagtgtaa aggtgacaag ggtagttttt cactaaaatc
    52261 gatattgact agattgatag tagccaataa ttctttagct tcgtctatgg ttgagcattg
    52321 ccctagtatc catggaataa actcaaatgg tgcaacgtta tcttttcctt cttgtaattc
    52381 tttataatca gcattgccag gaaaattcag tcctgccata ctcaaccctt tttcatttgt
    52441 agcctcataa tagagtggat agttggatac cccagctgct attcctatca ttgcataatg
    52501 tttatctaaa ttttttacct ttctaaaatc gaaacgataa tttcttggag taatagtgac
    52561 tacttcatta taagacatct cataatcaaa attccttcca aaataatggt ctttcgttgc
    52621 ataagtgatt gcggtacaca tcgttttccc tcctaaaaca aatcgttttt acacttttat
    52681 cttacatcta gtattttttt ttatcaaaaa aaaggccaaa gaagattgat ttactagcat
    52741 ttataaaaaa tagtactcag ggggaatcaa aaaatattgt aggttaaaag tacaacaata
    52801 aggggctgtg acaaaagtct tgtcacagcc ccttattccg aacaaacggt gttcaaaagc
    52861 ttgcatctgc ggtaataagc ccaaccaaac gaaaaaatag gaaaagctat ttttgtttgg
    52921 ccgttcttat tacttgatgc aggacagctt cttcacaacc tctaatcgtt gatataagga
    52981 aggtacagga tttatatatg actggtaata gaagaaaatt actagaatat tttagcgatt
    53041 taccctaatt tttgcttcta gttataaaat attagtacta actaaatttc aaaacgtagt
    53101 caaaaacgta tttaaaattg taatcgggta agtgttcgac aactataatt aaactagatt
    53161 tatctatgta cttccccctc aaaattgagg ggatattttt taccatttag gaatcgtcaa
    53221 tacgtattca ggaaaatcta ttttaaggtt
//
LOCUS       DAXQKX010000016        49819 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.016, whole genome shotgun sequence.
ACCESSION   DAXQKX010000016 DAXQKX010000000
VERSION     DAXQKX010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 49819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49819
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.016"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(89..1240)
                     /locus_tag="ACF3MF_000992"
     CDS             complement(89..1240)
                     /locus_tag="ACF3MF_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFE3927008.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(1394..1924)
                     /locus_tag="ACF3MF_000993"
     CDS             complement(1394..1924)
                     /locus_tag="ACF3MF_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HFE3927009.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(2023..2373)
                     /locus_tag="ACF3MF_000994"
     CDS             complement(2023..2373)
                     /locus_tag="ACF3MF_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HFE3927010.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(2530..4059)
                     /gene="ahpF"
                     /locus_tag="ACF3MF_000995"
     CDS             complement(2530..4059)
                     /gene="ahpF"
                     /locus_tag="ACF3MF_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008785 - alkyl hydroperoxide reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000302 - response to reactive oxygen
                     species [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HFE3927011.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(4069..4632)
                     /gene="ahpC"
                     /locus_tag="ACF3MF_000996"
     CDS             complement(4069..4632)
                     /gene="ahpC"
                     /locus_tag="ACF3MF_000996"
                     /EC_number="1.11.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0102039 - NADH-dependent peroxiredoxin
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="HFE3927012.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(4776..5438)
                     /locus_tag="ACF3MF_000997"
     CDS             complement(4776..5438)
                     /locus_tag="ACF3MF_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFE3927013.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            5622..7268
                     /locus_tag="ACF3MF_000998"
     CDS             5622..7268
                     /locus_tag="ACF3MF_000998"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HFE3927014.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAALLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPDMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDFQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            7259..8341
                     /gene="uxuA"
                     /locus_tag="ACF3MF_000999"
     CDS             7259..8341
                     /gene="uxuA"
                     /locus_tag="ACF3MF_000999"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFE3927015.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFELPGWEP
                     ERLAHIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLP
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNEYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(8449..10002)
                     /locus_tag="ACF3MF_001000"
     CDS             complement(8449..10002)
                     /locus_tag="ACF3MF_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3927016.1"
                     /translation="MQTQEAIKTFLLKKKSNTKLDIFLFLSEHRFFITTQYLADHFHM
                     SESNFLLYIKELEQDFERLNLTELHIDKQKPFLKLNFEGIDPAYCYYRLFGRYCNESV
                     SYQILTSLFSCQTNSIISLSQQTNYSASYLYTKMKKINAFLALYGLSISFSNNGRKSF
                     SGKEVQIQYAALDIYWNIFSSTATEFYDEDPQVVAFMMNTFFKKEVLDRLNSGMIDKL
                     YFLLKICKENFPATSVKDVQKEFTEYEYIDFFIDPSVDILRPNLPICREQRILVNILA
                     RLSITKIESEETSLEQYKLLKKANVPHVLYSREMVESFCTVFDLFIPEKEKILYSLAF
                     ARNKLYNGFLNFNQPNTPLPTFMLYQEHSVLKEVQTAIEQFYMDFREQNQHLLPVILE
                     KENVQWMVEDLVHLYDRYKKQPRIVIGVNYTRDFYISKDLIVKIEQIFSNESIKIQND
                     FMENCNIVISDCPLKQLPSHIKKIYILKGIITPEDWKKVIMRISEYIFELKEEALMDQ
                     SKKENQVTS"
     gene            10150..11439
                     /locus_tag="ACF3MF_001001"
     CDS             10150..11439
                     /locus_tag="ACF3MF_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFE3927017.1"
                     /translation="MRYSTILISTFAALSLSLTINQTVHTEEIETAKWTETKWANVNR
                     ITFQDEFSSFNSGVAKLRKGQTATIKAKIDYSGDLAPILQSAVTFENVDPALSIGYDE
                     NTLTIQHKQAIFTFTVTLNQDLLKPALFTVKVSDGLPNDHHHLTPYSQRQTIEQDSAI
                     DSGGDLVEEPTDKPENENKPEVPPTENPDGEQKPEIEPGEEPDTETQPEPDNESKPEI
                     TPGEKPDVNPEEKPDVTPEPDTDSGNQTVPETNPDTDNETENPEKPEVAPEEKPDVTP
                     EPDTDSGNQTVPETNPDTDNETENPEKPEVDPEEKPDVTPEPDTDARDQGIPEKINKK
                     TIQEDGKKESKKSNLAILKINEEQLNKKSRIFDSAQSAETLKSSKDTTFASPETKNKQ
                     LPKSGESQNKVILWSGIILLSIATMLSAKRFKQNRSL"
     gene            complement(11565..12644)
                     /locus_tag="ACF3MF_001002"
     CDS             complement(11565..12644)
                     /locus_tag="ACF3MF_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFE3927018.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVIDFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVIALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(12753..13193)
                     /locus_tag="ACF3MF_001003"
     CDS             complement(12753..13193)
                     /locus_tag="ACF3MF_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFE3927019.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTSLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTPQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(13250..13660)
                     /locus_tag="ACF3MF_001004"
     CDS             complement(13250..13660)
                     /locus_tag="ACF3MF_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HFE3927020.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(13841..14275)
                     /locus_tag="ACF3MF_001005"
     CDS             complement(13841..14275)
                     /locus_tag="ACF3MF_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFE3927021.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVSFEERKQLFEKYM"
     gene            complement(14376..15224)
                     /locus_tag="ACF3MF_001006"
     CDS             complement(14376..15224)
                     /locus_tag="ACF3MF_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFE3927022.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFVFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            15613..17379
                     /locus_tag="ACF3MF_001007"
     CDS             15613..17379
                     /locus_tag="ACF3MF_001007"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HFE3927023.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYMLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETRRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVRDHLDYLTDLGVNGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVYDREDKLYFTRELEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            17481..18740
                     /locus_tag="ACF3MF_001008"
     CDS             17481..18740
                     /locus_tag="ACF3MF_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFE3927024.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            18887..20188
                     /locus_tag="ACF3MF_001009"
     CDS             18887..20188
                     /locus_tag="ACF3MF_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFE3927025.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            20191..21042
                     /locus_tag="ACF3MF_001010"
     CDS             20191..21042
                     /locus_tag="ACF3MF_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HFE3927026.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            21055..21870
                     /locus_tag="ACF3MF_001011"
     CDS             21055..21870
                     /locus_tag="ACF3MF_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HFE3927027.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            22021..23187
                     /locus_tag="ACF3MF_001012"
     CDS             22021..23187
                     /locus_tag="ACF3MF_001012"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFE3927028.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            23417..24064
                     /locus_tag="ACF3MF_001013"
     CDS             23417..24064
                     /locus_tag="ACF3MF_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFE3927029.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            24148..25092
                     /locus_tag="ACF3MF_001014"
     CDS             24148..25092
                     /locus_tag="ACF3MF_001014"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HFE3927030.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            25227..26678
                     /locus_tag="ACF3MF_001015"
     CDS             25227..26678
                     /locus_tag="ACF3MF_001015"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HFE3927031.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDIFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            26725..27534
                     /locus_tag="ACF3MF_001016"
     CDS             26725..27534
                     /locus_tag="ACF3MF_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFE3927032.1"
                     /translation="MTSAFFILSACGTAAANQEDNSWSNVEKKKELVVATSGTLFPAS
                     YYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFAANDFGITKE
                     REKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMRLAEKHGAKL
                     VTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVYFNENESGFL
                     LKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESVSE"
     gene            27534..28193
                     /locus_tag="ACF3MF_001017"
     CDS             27534..28193
                     /locus_tag="ACF3MF_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFE3927033.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            28319..29008
                     /locus_tag="ACF3MF_001018"
     CDS             28319..29008
                     /locus_tag="ACF3MF_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927034.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            29014..29970
                     /locus_tag="ACF3MF_001019"
     CDS             29014..29970
                     /locus_tag="ACF3MF_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HFE3927035.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            30014..30526
                     /locus_tag="ACF3MF_001020"
     CDS             30014..30526
                     /locus_tag="ACF3MF_001020"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFE3927036.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(30782..31330)
                     /locus_tag="ACF3MF_001021"
     CDS             complement(30782..31330)
                     /locus_tag="ACF3MF_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFE3927037.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(31419..32600)
                     /locus_tag="ACF3MF_001022"
     CDS             complement(31419..32600)
                     /locus_tag="ACF3MF_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside transporter C-terminal
                     domain-containing protein"
                     /protein_id="HFE3927038.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(32836..34344)
                     /locus_tag="ACF3MF_001023"
     CDS             complement(32836..34344)
                     /locus_tag="ACF3MF_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HFE3927039.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            34503..34694
                     /locus_tag="ACF3MF_001024"
     CDS             34503..34694
                     /locus_tag="ACF3MF_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927040.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            34897..35814
                     /locus_tag="ACF3MF_001025"
     CDS             34897..35814
                     /locus_tag="ACF3MF_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coiled-coil domain-containing protein"
                     /protein_id="HFE3927041.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            35807..36880
                     /locus_tag="ACF3MF_001026"
     CDS             35807..36880
                     /locus_tag="ACF3MF_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927042.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            37028..37546
                     /locus_tag="ACF3MF_001027"
     CDS             37028..37546
                     /locus_tag="ACF3MF_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927043.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            37527..37919
                     /locus_tag="ACF3MF_001028"
     CDS             37527..37919
                     /locus_tag="ACF3MF_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HFE3927044.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            37995..38930
                     /locus_tag="ACF3MF_001029"
     CDS             37995..38930
                     /locus_tag="ACF3MF_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFE3927045.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            39063..39842
                     /locus_tag="ACF3MF_001030"
     CDS             39063..39842
                     /locus_tag="ACF3MF_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HFE3927046.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            39835..40152
                     /locus_tag="ACF3MF_001031"
     CDS             39835..40152
                     /locus_tag="ACF3MF_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HFE3927047.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            40396..42006
                     /locus_tag="ACF3MF_001032"
     CDS             40396..42006
                     /locus_tag="ACF3MF_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFE3927048.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            42163..43011
                     /locus_tag="ACF3MF_001033"
     CDS             42163..43011
                     /locus_tag="ACF3MF_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFE3927049.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            43242..43721
                     /locus_tag="ACF3MF_001034"
     CDS             43242..43721
                     /locus_tag="ACF3MF_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6530 family protein"
                     /protein_id="HFE3927050.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            43754..45982
                     /locus_tag="ACF3MF_001035"
     CDS             43754..45982
                     /locus_tag="ACF3MF_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFE3927051.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            46111..47754
                     /locus_tag="ACF3MF_001036"
     CDS             46111..47754
                     /locus_tag="ACF3MF_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFE3927052.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQESGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(47827..48372)
                     /locus_tag="ACF3MF_001037"
     CDS             complement(47827..48372)
                     /locus_tag="ACF3MF_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HFE3927053.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(48395..48880)
                     /locus_tag="ACF3MF_001038"
     CDS             complement(48395..48880)
                     /locus_tag="ACF3MF_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFE3927054.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(48870..49682)
                     /locus_tag="ACF3MF_001039"
     CDS             complement(48870..49682)
                     /locus_tag="ACF3MF_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HFE3927055.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
BASE COUNT        16557 a         9057 c         9563 g        14642 t
ORIGIN      
        1 gtaaaaggac tgtggcgtta tcgtcacagt ccttttttca aataaacggt tttcacgatg
       61 tctctttcac aacttctttt tgatttactc acacttcata aacttttttt gtaaaatatt
      121 tgagaacaag tggagaaata agtgtactta ataaaatcac gataactaaa ggtgaatagt
      181 actgtggttc gatcaattga ctttgctgtc caatttgtaa aatgatcaaa gccatttctc
      241 cacgcgaaat cataccagca ccgaccatca atgaactatg ttgagaaaaa ccggcaatct
      301 gagcaccaaa ataacctcca agcaatttgg tcaaaatcgc tacaagcgtc aatatagaaa
      361 taaagagtag ttgttcacta aagtcagaaa aatcaacttc taatcctaca ctgacaaaaa
      421 atactggtat aaatactgca tatcctaaag cctctacatt gtggtatact tcttctttaa
      481 cctttgtctg actgacagct atcccagcaa aaaaagcacc aatgacagag ctaagcccaa
      541 caagatccgc tacgtaagac attcctaaac aaataactag cgatacgatg ataatagaag
      601 aatttgcgta cactttttct gcaaatgaaa gtaggaaagg cgcaatccat ttgactaata
      661 agaaaataaa aacaaaataa attagctgtt caatcaaaac aagcggtaaa gaagcattgc
      721 tagaagcttc ccccgttaga aaagataggc tgaaacttag aactaaaacg actaaaatgt
      781 catctaccac agaagcaccc aaaattgttg atccttcttt tgtattcact acgtttagtt
      841 cttttaatac ttctactgaa atactgacag aagttgccgc aagaataatc ccaaagaaaa
      901 tcgcttcatt tcccgaaact tggaatgctt tgcctgtcaa ccagccaaaa acaaccggga
      961 agatgatccc aagcaaagca acgaacatac caggtcggaa atattttttc aaaagagata
     1021 aatcactttc cagaccagct aaaaacatta ataagatcac accaatctcc gaaaagtcat
     1081 ggactagaat atcaggtttg acccaattca atccagcttg gcctagcaaa acaccaacaa
     1141 gtaattgtcc aatcactgct gggataccta atctccgcga gatatgtgag ccaatcgttg
     1201 ttgaaatcaa tatcaggcat aaaataccaa taaattccat tctcatcatt cctttgtata
     1261 aaatatagcc cgaacttagc ataacataca ttattgaaaa aataggaaaa tatactcaca
     1321 aaaaaaccaa caatccaaaa gatttttttg gattgttggt ttttatacgg tctattttaa
     1381 taactaaaaa tgattaacgt atagtcattt ttcttattct gatgaaattg ataatctcct
     1441 ggatgcccat gaaaatcaaa ataaagccga atatttggaa tagaagcatc aaacttttga
     1501 atggattgaa caataagacg aatccgccaa tcaacaacag aatactacta taaacactcc
     1561 aacttttagc ttttgtattc atgctgaaga acaactggaa caagctgttg atgataacag
     1621 ctaatccaag aagaatcggc aggatagaaa cgattgcagg tgcaaaagca tagacgatca
     1681 gagctaagat caggaaaaaa agaccactga acagaccgat actccaagaa cctgttttcc
     1741 ttttaaaacg gtaagcctca aaaagattca acaacccaag caaaacaaga taggcggtga
     1801 tcagataacc gataaaatga aaaacagcag aagggtttag cacaatcgca atcccagaaa
     1861 taatataaac agcagctctt aataaggcgt atttttgaat attttgttta atcgtctcaa
     1921 acatataaga aaacctcctt tgacttattt taacgtgaac tagtcatttt accaaattaa
     1981 atgttacaaa atgagcgaag gagaagaata tctctggaaa aatcaacttc tgaggatctt
     2041 ttccattttt ttgccttttg ctagctcatc gatcatttta tctaaataac gaatttcttt
     2101 catcaagtta tcctcgatgt cttctactcg tacaccacaa acaacacctg taatcaagga
     2161 acgtgaagga ttggggacag gggcttccgc aaaaaattgt tcgaaagtca cttgtttttg
     2221 tagttgatat tctagttctg tttgggaata acccgtcagc caacaaatga tttcatctac
     2281 ttcctctttt atacgatctt ttctctccgc ttttgctaca tacataggat aaacgcttgc
     2341 aaaacttgtc gtaaaaatac gattttgcgc cataatcagt cacctttctt tttttcaaat
     2401 tatttactac ttatagtata taagaaaaag agaagaaaaa gcgattattc aaaaaaacaa
     2461 aaaggattgt gacaaaattc ttgtcaccat ccttttttcc gctctctgac tttttacaat
     2521 cttcatagct caagtgcgca tcagataatc gaatgctcct aaagctgcag tagctcctga
     2581 acccattgaa acaatgattt gtttgtatgg actatctgta caatcaccag ctgcgaaaac
     2641 gccggggata ttcgttgcgc catttttctc ggtcactatt tcatttcttg gattcatttc
     2701 gatcgttcca tctagccaat ccgtattagg gagtaagccg actagaatga atactcctga
     2761 aacagctagt gtatgcatct ccatcgtacg gcgatcgata taggagagag attctacctg
     2821 attcgtaccg ctgatttctt tcgtcgctgc atgtttgata acagtgacat tcgcaagaga
     2881 gactagttta tcctgtaaga tttgatctgc ttttaattct ggtaagaatt ctagaacata
     2941 tacatgtttt gctaacccag ccaaatcgat tgctgcttca acaccagaat taccaccacc
     3001 gataacagca atctcttttc ctttaaataa agggccgtca cagtgtgggc aataagcaat
     3061 tcctttattt ttaaactctt tttcgcctgg tacattgata gaacgccagt gcgcacctgt
     3121 cgcgatgatg gcggtttttg ctttaagtga tataccgtta gctaagccaa tattaataaa
     3181 atgttgctct ttatttaagg aaacggcctg ttgattcatc ataatgtcga tagggtaact
     3241 acgcacatga ctttctactt gctgcatcaa ttttggacct tctgtgtaag aggtaccaat
     3301 catattttca atccctagtg tttcaacgac ttgtccgccg aaagaatcag cgacaagtcc
     3361 tgtacggatt cctttacgtg ctgcatagat agctgcacta ctagctgctg gtccaccgcc
     3421 aatcactaat acatcataag gttctttttc aaacaactct tcttcaatca aagggccagt
     3481 gattttttca acaatttgtt cgatcgtcat gcgtccgcta ctaaattctt ctccatttaa
     3541 aaacacagtt ggcactgcca tgattttttt atcatcgatt tctttttgga acatcccacc
     3601 ttcaatcatc gtatgagtaa tatttggatt taatacagct aatatattca atgcctgtac
     3661 aacgtcgggg caattatgac aagtcaagct aacataactg tcaaaatgca atgtttgtgt
     3721 tatttttttg attttaagac tcaaagattc actgattttc ggtgcccgtc cactaatttg
     3781 taacatagcc agtaaaaaag aggaaaattc atgaccgagg gggataccag caaaaacgat
     3841 tccactttct ttgccaactg gattgataga aaaactaggt gtgcgcatcg aatctctttt
     3901 ttcccaagag attttaggag acatttctgc tatttccttc gtaaattcag ctagtttttg
     3961 actattttca ctattatcca aactaacaga aaaaacaata ggagattcaa tcagtgctaa
     4021 atattgttcg agattttgtt tagtttcttt gtctaacata tccaccacct aaatctttcc
     4081 aacaagatca aaacttggtt tcaatgtttc gccactttct ttccattttg ccggacaaac
     4141 ttcacctggg tgggtacgta catattgagc agcgcgaatc ttatcaatca gtgcactagc
     4201 gtcacgaccg attccatctg cattgatttc catagcttga acgattccgt ctggatcaat
     4261 aataaatgtt cctcgctgag ctaatccttg ctcttcatcc aaaacatcaa aaatacgaga
     4321 aatctgatga gacggatcac cgatcatcac gtattcgatt ttaccgatag catctgatgt
     4381 atcatgccat gctttgtgag taaagtgggt atcggtagag caagaaaaga cttcaacacc
     4441 taaagatttc aatgtactgt attgttcttg taagtcttct aattcagtag gacaaacaaa
     4501 agtaaaatca gctggataga agcaaagaat actccagttc cccataagat ctttttcact
     4561 gacttctaaa aattctcctt gatgataagc atgtgcatta aattcttcga tttttttccc
     4621 aatcaatgac atagtaaaac ctccaataat aattatttat ttataattat tgtaatttag
     4681 ttggagttgc aaagtcaatg gatattttgt tatttaataa agattactca aaaacgaagg
     4741 ttaattataa aaatagaaga ggtcgcaaga aaatgctact gctggaaata ctcgggataa
     4801 cgttgagtaa cagtttcctg ttctttcagc atcatgtgta agtgcaatcc cgtttgaaat
     4861 cgagcttctt ctggtttttt atcaactaaa gccttgagta aatcataatg ttgttccatg
     4921 atcgtttccc atggaagccc ctgaatggtc actcgtaacc agcggaaacg ttctaaatgg
     4981 gtattatggt catctaacca gttccaaact tcttttcttc ctgcaatttc gaaacaagct
     5041 tcatgaaata aattatctgc acggaaaaaa gcgcgttcgt catttatttt gactgctttt
     5101 tcttgttctt ctaaaatcgt ttctagcact attcgtgttt gtgtgtccaa tttggaacaa
     5161 cattcaatca tgatttgctc ttccaactgt tctcggacaa agcgagcatt ttctgcagaa
     5221 acaagattaa ttttggaaac atacgtacca ctttgaggta tcgtatacac gagttcttgc
     5281 tgacgtagtt gaatcaatgc ttcgcgaatg ggagtccggc cgatagcaag atgttcctcc
     5341 agtgcctttt cagatatttt ccttccaggt tctaagtcag catagataat ttgtttacga
     5401 atcgcttgat aagcttgtga ttgcaagctg cttttcatct ttattcctcc aaaatcattt
     5461 ctatgaacgt agtataacag aagaggtctg aaaaacaatc tggtatgtca cattaactag
     5521 taaatttgta taaatagtaa aattttggtt gacatagcga tttttattgc ataaaattca
     5581 cttgaataca aaaactaata tgttagttta ggaggggaaa aatgattgat ttaaacaact
     5641 ggaggaactt tatccctgaa ttatctcaaa aagaagtaga aatacctcat tttgaccgtg
     5701 catcattaag agaaaatgga caaaaaaatc ctgtctggat ccatttcggt ggcggaaatc
     5761 tttatcgagg atttcatgca gaaatcgctc aacgtttagc ggatctaggc gaattgtcca
     5821 ctggtgtcat tgtttgtgaa acattcgatg aagaaataat tgaaagggct taccaagatt
     5881 ttgatgattt gattcttgaa gtggtcatgc caagcagtgg agagttcgtc aaacgtatat
     5941 tagctgcgac agctgacagt ctgtattgtc atccagattg ttctgaacac tttgataaga
     6001 tgattcgaca ctttgaaaat cctagtttac aattagttac ttttgctatt actgaaaaag
     6061 gttatcgatt gaaagataca aataataaat atataggacc gattgcagtc gatataaaaa
     6121 atggtccaaa gaagccatca catacaatga gtattcttgc tgcgctactt tataaacgtt
     6181 ttttatctgg agcttggccg attgcacttg tctctacaga taatttttca caaaacggta
     6241 gtcaattacg tacttctttg ctaacgatcg caaaagaatg gcaaaaggaa ggttatgtac
     6301 aaaatacatt tatccaatac ttatcgaatg aagaaattgt tgcgtttcca tggacgatga
     6361 ttgatcgtat caccccgaat ccttccttgt cagttagcaa aatgttggca aaagagggct
     6421 tttcaaatat gtcgattttc caaaccgcaa aaggaaataa tattgctcca tttgtcaata
     6481 cagaggacat ccattattta atcatggaag atcattttcc caatggacgt ccgaaattcg
     6541 aaaaagctgg ggtattcttg actgatcgtg caacggtaga taaagcagat acgatgaagg
     6601 tgacgacttg ccttaatcct ttgcatacgt ctttagctat tatgggttgt ttactggggt
     6661 ataggagcat agctgaggag atgaaagatc cagatttatc gctgctagtt tctgaaatcg
     6721 ggtacaatga aggcctccca gttgtggagt ctccaggtat cattgatcca aagatctttc
     6781 tggaagaagt aattactgtg cgcttttcta atccaaatat tcctgatatg cctcagcgaa
     6841 tcgccacgga tacctctcaa aaggtggcga ttcgttatgg tgagacgatt aaaaaatata
     6901 tggaaataga agttaaagac ccgcagacac ttgtattcat accattgact ctcgctgctt
     6961 ggcttcgata ccttattggc attgatgatc aaggaaaacc attcatcccg agtccagacc
     7021 cactattgac agactttcag cataagcttt ccgatattca actgggtacg caagatacat
     7081 cacatattca tgagaaaatg gctcctattt tgtcaaataa agaaattttt ggtgtagatc
     7141 tttaccaagc agagcttggc agaaaaatag aagaaatgtt catcaagatg gtagcaggac
     7201 cgaatgccgt acgaaaaaca ttacaggatt acttacaaga acatggagga aatttatcat
     7261 ggaaatgact tttagatggt acggatcaca ggaagaaaag attaccttag atgaaatcag
     7321 acagattcct gcggtcaaag ggattgtagg cacattgatg gatataccag taggagaggt
     7381 atggcccagg gagaggatca aagaactaaa agaagaaatt gagtctcgtg ggttaacact
     7441 aaaagtaatt gaaagcgtca atgtgcatga tgccattaaa attggattac cttcccgtga
     7501 gcagtatatc gaaaactata agcagacaat ccgaaacttg gcagaatatg gaatagaagt
     7561 catctgctat aattttatgc ctgtatttga ctgggtgaaa tctgaccttg actaccgctt
     7621 agaagacggc tcatccacgt tagcttttat atctgatgat attccagatg atccaagaga
     7681 aatcgtcgcg cgcatcgaac attccagcaa tgaatttgaa ttgccgggat gggaacctga
     7741 gcgcttagct catatcaaat ccttgcttga agcctatgca tcagtagacg aagaaaaact
     7801 tcgagaaaat tttgcctatt ttctccaatc aatcatccca acatgtgaag aggtaggggt
     7861 caaaatggct gtacatccag atgatccgcc atactcgatt tttggattac ctcgaatcgt
     7921 aaagaatcga gaagatttag attggttgtg ccgcatagta gacagccctt ataacggaat
     7981 cactctttgt acagggagta ttgcagaaga tccagaaaat gatgtatatg ggattttagc
     8041 agaattttgt caaagagatc gaatcccatt tgcacatgtt cgaaatatta aatttttagc
     8101 taatcgagat ttctatgagg caccgcataa atccgaatac ggttcattag acatgtaccg
     8161 catactaaaa acaatgtatg acaacggatt taacgaatac atccgtcctg atcatggaag
     8221 aatgatctgg aatgagacag gaagaccagg atacggctta tatgatcgag cattaggtgc
     8281 tgtttatcta aatggattat gggaagcaat cgaaaaagga aacaaaagta aagataatta
     8341 gtgaaaaaaa ctgtaatttt attatgtaaa taagaaggat gttcaaattc ttgatacata
     8401 aatccggagg ttgttaataa gcattcggat ttatgtatct tatttggtct aggaagtaac
     8461 ttgattttct tttttcgatt gatccatgag tgcttcttct tttaattcaa agatatattc
     8521 tgagatcctc ataatcactt ttttccagtc ttctggtgtg atgattcctt ttaaaatata
     8581 gatttttttg atatgagaag gcaattgttt caaagggcag tcgctgataa cgatgttgca
     8641 gttctccata aaatcatttt gtattttgat cgattcattt gaaaaaattt gttctatctt
     8701 aacgatcaga tctttactga tataaaaatc acgcgtatag ttcacaccaa tcacaattcg
     8761 cggctgtttt ttgtagcgat catacaaatg tactaggtct tcaaccatcc attgcacatt
     8821 ttccttttct aaaataactg gtaacaagtg ttgattttgt tctctgaaat ccatataaaa
     8881 ttgttcaatg gcggtttgga cttctttcaa cacgctatgt tcttgataaa gcatgaaagt
     8941 aggaaggggc gtatttggtt gattgaagtt aagaaatcca ttataaagtt tatttcgtgc
     9001 gaatgccaat gagtaaagaa tcttttcttt ttcaggtata aacaaatcaa atacagtaca
     9061 aaaggactcc accatttctc ttgaataaag aacatgagga acgtttgctt tttttaaaag
     9121 tttgtattgc tccaagcttg tttcttccga ttcgattttc gtgatagaaa gtcgagctaa
     9181 aatattcact aagatgcgtt gttcgcgaca aattggcaga ttaggtcgca aaatatctac
     9241 agagggatca ataaaaaagt caatatattc atactctgtg aattcttttt gtacgtcttt
     9301 cacagaagtt gcaggaaaat tctctttaca tatttttaat agaaaatata atttatctat
     9361 cataccgcta tttagtcggt caagtacttc ttttttaaaa aaagtattca tcataaaagc
     9421 cactacttgc ggatcttcat cataaaattc tgtagcagta cttgaaaaga tgttccaata
     9481 aatatctaat gctgcatatt gaatttgtac ctcttttcca gaaaaagact ttctgccatt
     9541 attagaaaag gagatagaca aaccgtacaa tgctaaaaat gcattaatct ttttcatttt
     9601 cgtatacaaa taagaggcac tatagtttgt ttgctgactt aaactgataa tcgaatttgt
     9661 ctgacagctg aacaaagaag tcaagatctg ataactgact gattcgttgc agtatcttcc
     9721 aaatagacga taatagcagt aagccggatc aattccttca aaattcaact ttaaaaaagg
     9781 tttttgctta tcaatatgca gttctgttag attgagacgc tcaaagtctt gttctaattc
     9841 tttgatgtat agtaaaaaat ttgattcaga catatggaaa tgatctgcta aatattgtgt
     9901 agtaataaag aaacgatgtt cagataggaa aagaaaaata tctaattttg tattgctttt
     9961 tttcttcaag agaaacgttt taatcgcttc ttgagtttgc atgaaagagg ctccttttta
    10021 cttaaattgt taaaacttga aaatattact gtttttttca taaatttaga caaaaaaaca
    10081 gtaaacatat aggtagaatc tctactatct tatttcttgc atacaaaaaa atcaaggagt
    10141 gagagagtta tgagatattc aaccatctta atatcaacat ttgcagcctt aagcttatcg
    10201 cttactataa atcagacagt ccacacagag gagatagaaa cagccaaatg gacagaaacc
    10261 aagtgggcca acgtcaatcg aattaccttt caggatgaat tttcatcctt caattcagga
    10321 gtcgcaaaat taagaaaagg acaaacagcg accatcaaag caaaaattga ctattcagga
    10381 gacttagcac ctatactaca atcagctgtt acatttgaga atgttgatcc cgctttgtcg
    10441 attggctatg acgagaacac tttgactatc caacacaagc aagcgatatt taccttcacc
    10501 gttacattaa atcaggactt gttaaaacca gcgcttttta ctgtcaaggt atcagatgga
    10561 ctaccgaacg atcatcatca tttaacgccg tatagtcagc ggcagacaat tgagcaagat
    10621 tcagctatcg actcaggagg agatcttgtt gaagaaccaa cagataaacc agaaaatgaa
    10681 aataagccag aagtaccgcc tacagaaaat ccagacggag aacagaaacc ggaaatagaa
    10741 cctggagaag aacccgatac agaaactcaa ccagagccag acaatgaatc aaaacctgaa
    10801 ataacccctg gagaaaaacc agatgtaaac ccagaagaaa aaccagatgt gactccagaa
    10861 ccagatacgg attctggaaa ccaaacagta ccggaaacaa atccagacac agataatgaa
    10921 actgaaaatc cagaaaaacc agaggtagcc ccagaagaaa aaccagatgt aactccagaa
    10981 ccagatacgg attctggaaa ccaaacagta ccggaaacaa atccagacac agataatgaa
    11041 actgaaaatc cagaaaaacc agaggtagat ccagaagaaa aaccagatgt gactccagaa
    11101 ccagatacgg acgcaagaga ccaaggaata ccagaaaaaa taaacaaaaa aacaattcaa
    11161 gaggatggaa aaaaagagag taaaaaatca aatctagcaa ttctaaaaat aaatgaagag
    11221 cagctgaata aaaaatcacg aatatttgat agcgcccaat cagctgaaac cttaaaaagt
    11281 agcaaggata caacctttgc tagtcctgaa acgaaaaata aacagctacc aaaatccgga
    11341 gagtcacaaa acaaagttat actgtggagc ggaatcattc tattaagtat agcaacaatg
    11401 ctttctgcaa aaagatttaa acaaaacaga tctctctaac atttgaataa tgtctgtgaa
    11461 cgcatttttc aaataaaaag aaatatccag aaaacgaccc caaaatacca gattgaaatc
    11521 tgatatttgg ggtcgttcat actttatctt tcttcatatt tattttaagg gatatctgtt
    11581 tcttttggaa gatggttcgg gatctttttc actttcaata catctaaaaa gaaggtaaag
    11641 atcggaatgc cgacaatcaa gccccaaacg ccaaagaacc gttcgctaac aagtaagacc
    11701 acaaatgtat aaaaaatcgg cagttctgtt ttgctggaca tcaacttcgg attcagcaca
    11761 taagactcaa ttagatggac aatcaaaatc gtaatcagga tataaacaac atctcggatg
    11821 cctccttggg aataagctat gaaagataga ggaatacaag aaatgataac acctgctact
    11881 gggatcagac ttaaaatgaa aatcatgatc gctaaactca gcagctgatg aaagccaaat
    11941 acagccaagg cgattgtagt gagcaacgtg tttaaaagag cgataacaaa ttgagcttct
    12001 aataccaaac caaatgtatt gacaaactta tcggcaaaat agtaaatatc ttgaaagaac
    12061 caagaaaatt cactttttaa aaacaatctt gagaatacaa ttgttttttt cttttcaatc
    12121 ataaaaaaga aacttaagat gaatgacata gcaaacgcca ctgccatttt tcctatatcc
    12181 tgtaaatagc caagcgcaat cgaagcgcca ttttgaagct gttcaaaaaa atcgtttcgc
    12241 tcaatataag tatggatata ttgtaaaaca ggatctgcat cttttggctg atgctcgtaa
    12301 aaatcaataa cggactggat catatcaaat gtttgatgaa taagcatcgg gatatacttt
    12361 gtgaatgcca gatagataag gtaaacgatc agtgtataaa tcatgatagc taaaacacct
    12421 gtagggattc ggacaaatcg ctgaatgatt tgaacaagat gaatcatcaa ataagtaaag
    12481 ataaatgtga gcaaaatggt tgtaatcata cttctaacta agaaaagaac aaaaacgaca
    12541 aataataaaa cagtgagacg gcgtattttt tcattcgcca aaaaacgctg ataaacggtc
    12601 aaatcgacaa cctccaaata acaaaaaata aacacgttat tcattatatg atggaatatg
    12661 aaaataagaa agagaaagag caaaaagaaa aaccgctaaa tgacgttatc ttatgagttg
    12721 gttttcctca taaaatcgtt catctagcag tttcagccct ttttctggtc ttgatgaaaa
    12781 ttatctagca tttttcgggt cagatgttgc agtgtatcca attcttcctg ttcaagtgga
    12841 agataagact tgatcttttg tggaatacct tctgcttgtt tttgcaacgc agcaccttga
    12901 ggagtcagcg taacatttac gattctttca tcacccgttt cacgctgacg attaatataa
    12961 tttttttctg ctaacttttt tagtaaggga gtcagcgtac cagaatccag acacaaatca
    13021 tttcctagct ctttcactga agtctttttc ttttcccata aaactaacat cacaagatac
    13081 tgggtatagg taagattcag cggcttgagg agggaagtgt agtgtctaat gatttcctta
    13141 gaggcggcat ataaaggaaa acatacttga ttaactaaat atagatcttc catttttcca
    13201 cctccgctgt tttactatag tgtatcatag cggatttaca caaaaaagtc tattcactaa
    13261 ctgctttcag agtaacttct atatttccag ctgtagcttt tgaatacgga cacactttat
    13321 gcgctgcctc taataattct tgcgtttctt ccagagaaag accttcgata gatccttcaa
    13381 tctctacacc taagacaaag ctcgtttcac tttctgaata aagggaaact tgtgcactga
    13441 cagtagaagc cccagagata tttttttgct gtttgatcaa ttctaatgca ctgttaaaac
    13501 atgcactgaa accagctgca aacaattgtt cagggttggt tgcattttcg acgcgtttac
    13561 caggagctgc aatattcaat tcgaatgtac gatcgggatt atgaacttct ccagagcgtc
    13621 cgcctgtgtt gatcattttc gtagaataca tttttttcat aaaattacca cctttaatta
    13681 tattttatac aattgaattt tacacaatat aattgtggaa agcaaagaaa tggattggca
    13741 taagataaat aagagaaagc acatgaaaca gacgcgcttt ctcgaatagc aaacatatac
    13801 aaaaaaatat cagagacaaa aactaatctc atcataaaca ttacatatat ttctcaaaaa
    13861 gttgttttct ttcttcaaaa cttacttcac gatggacctg atgaagcatc cataaataac
    13921 caaaaggatc tctgaacatt gagttagtca caccaaagtc catcatttct gtcatttctt
    13981 gaatctctac acagccattt cgtaatgctt tattatgtgt gtcctcgata tcagagacga
    14041 tgatattgaa ccagatcgta tttggatgtt cagcagtagg agcagtcaaa ccaagagacg
    14101 tgttttcatc cagcatatgg aatctcgtgc catacaaggt aaaaatgact tcattattgc
    14161 ctctagggta atctgttgcc tcaatcagtt gtatttcatc aaagattgtt tgatacagtt
    14221 ctagtgcttt caaactatca tttaatacaa aatctatttc cgttccttta tgcataaaga
    14281 tctcctctcc ttttcagtcg aacagttact agattctttt attataccag ttaaagaaaa
    14341 cgcattcaaa aaaaatagcg gatttactta ccaactcatt cgattggatg ataagtaaat
    14401 ccgcgtccca ttacttctgc tacgctgctg acaatgacaa aggcacttgg atcgatttct
    14461 tctatcaatg gtttcattcg ggaaaattca tgatcagtca caacgatcaa taaaacctct
    14521 tttgactttc gattataccc gccttttgcc tctagcaggg taaggccacg tccaatctca
    14581 gcacttaagc gaaggcggat gtcttccaaa taatgttcac tcatgaccat aacagatttc
    14641 tttcgattga tacctgtttc gatataagtc atgacaattg aagtgattgc aatagataaa
    14701 atagcataaa gaaactcttc tattccaaaa acaaacagat taagagaaac aacgaatgcg
    14761 tctgtaaaaa ataagccaat cgaagtattc aagtggaaat attttttaaa aatgagggga
    14821 gggatcgtcg taccgccgct agaagagttg tttttatata aaatcgcaac tcctaaagca
    14881 aaaatcgcac ttccaaaaat gacagacaac aaccgatctg aagtaatcat tgtttctgga
    14941 actattgcaa tgattaaagg aaaaaccaag cttccgaaaa gtactttaaa aaagggtttt
    15001 ttacctaaaa atagaagagc tagtaccaac ataacgatat tcaacactaa aataactata
    15061 gctcggtcaa atcctaaagc agcttccagt aatattccta gaccgctgac acctccagca
    15121 gcaatatgat gaggccctaa aaacatattg atagcgactc ctaatatgaa gagggcaaaa
    15181 ataatcttaa tgtatgtcca tataaattgt ctcgtttctt tcatttatcc acttccttaa
    15241 ttcattaata atactcttat cttattataa cttacttttc accttaagtt aactttaatt
    15301 aataaaaaaa ttaggctagt ctaaattatt atgtttcatt cttctagaat atacttctac
    15361 gttaaaaact gttaaaaaac ttttacttta gaaaattgga gaaattgatc gcttaagata
    15421 aattcaggac actaaatagt acaggaagta gattaaaact tttaaaagtt ttaagtctat
    15481 ctatttggca agtttaaaaa ataaaaattc ggtatcaaaa aactgttacc gataacattt
    15541 ttgaaagcgt tgtcttttgt ttctctatca cttatagtga tgacgtcata ttaaaacaca
    15601 aggaggaaat caatggatac agctgcaatt tatcatcgac cggaaagtga atatgcattt
    15661 ctatatacga atacaagatt tcgtattcgg cttcgtacta ggaaaaatga tatcaaaaaa
    15721 gtatatatgc tttgtggaga tccatatacc ataacaactg aaaaatggta tcaaaaacaa
    15781 cgaccaatga aaaaatgtct aagtaccaat gttcatgatt attgggaaat tgaagtgacg
    15841 agcgaaacaa ggcgcttaca gtatgcgttc catgttgttg gggaagataa cacggactgt
    15901 ttttacggtg atcaaggaat ttttccttat cgagaaaatg tgattactga accaaatttt
    15961 tattttcgaa taccttattt tcatcaaatc gatcgattca ctattccaga atgggtaaaa
    16021 gaaacagtat ggtatcaaat ttttcccgaa agatttgcaa acggggacaa agcaaatgac
    16081 cccgaacaca ctttaccttg gggaagtaaa gatccagacc gagaagactt cttcggggga
    16141 gatttgcaag gtgtgaggga tcatttggat tacttgacgg accttggcgt caatggcatc
    16201 tatttttgtc ccatatttaa agccacatcc aatcataaat acgatacgat tgattattat
    16261 gaggtggatc ccgcttttgg cgataaaaaa cttttaaaaa acttgattga tgaagcacat
    16321 aaaagaggga tacgtatcat gttcgatgct gtattcaatc atatgggtgt ccattcacca
    16381 cagtggcaag acgttctcaa aaacggagaa aaatcgatct ataaagactg gttccacatc
    16441 cgttttttcc cagtagattc ttatcagatg actgacttac cagaaactgc tgaaaatatc
    16501 ccatatgata cttttgcttt tactccattc atgccgaaac taaatacagc aaatccagaa
    16561 gtgcaaaaat atttgctgga tatcgcaact tattggataa aagaattcga tattgatgga
    16621 tggcgtcttg atgttgctaa tgaagtcgat catcattttt ggaaaaaatt cagagaagca
    16681 gttacagaaa tcaaaccaga catctatatc cttggagaga tttggcattc ctctcaagct
    16741 tggctgcaag gggatgaatt ccatgcagtg atgaattatg cattcacaga ttcgattaaa
    16801 gattattttg caaaaaagaa aatcacagct tcacaaatgg tcagtggaat gaatcatcag
    16861 caaatgcttt acagagatca ggtgaacgaa ggaacattca acttattaga ttctcatgat
    16921 actgccagga tcttgaccct ttgccaaggt aacaaagaat tgatgaagtc tgtgatggcc
    16981 tttatgtttc ttcaaaaagg gtctccttgt atctattacg ggacagaaat agggatgact
    17041 ggtgaagatg acccggattg ccgcaaatgt atgatatggg agaaggagga acaagatcta
    17101 gagctattcg gttttataaa agaacttgtt tctctaagga aacagttgtc taagattatt
    17161 tctgaaggtt ctactcagtg gctaatagta tatgatcgtg aagataagct ctatttcaca
    17221 cgggaactag agggacagat catctatgtt tactttaatc agtcaaaaga accttgggta
    17281 gtagaacagg aaaatgaggt gattcttagt caaaattgtc agttgttaga agacgggaaa
    17341 gcagagatac gacaatacgg atttttgatc atgtgttgaa aactgttacc ggtaacaaca
    17401 agaaagcgtt tgcaaatgaa gatttgtgcc cattataata agggtgtaac agcacgttga
    17461 atacacagga ggaaatgaag atgaaaaaaa gaagtgtgaa acagttgggt ttagggttaa
    17521 tctctttagg aatcttaggc ggattagcgg cttgtggcaa tggtaactct tcagcagaag
    17581 gggaagccga tgaaggaaaa acgttaacag tttccgttga ttctggatat aaagattata
    17641 taaacgaaat aaaaaacact ttcgaaaaag aaaacgatgt gaaaatcaag ctagtagaaa
    17701 aggacatgtt cgatcagttg gaatcattag cgttagatgg gcctgctgga aagggacctg
    17761 acgttatgat ggcagcatat gaccggatcg gtgcgttagg acagcaagga catctggcgg
    17821 aagtaaaact gggaaatgaa gcagcttacg atgaaacaga caaagcccaa gtgacttatg
    17881 atggaaaaat ctacggagaa cctgcagtaa tcgagaccct tgttttgtac tataacaaag
    17941 atttagtcga tacagcacca tcaacgttta aagatttgga gaatctatcc aaagacagtc
    18001 gttttgcttt tgagtcagaa gcaggaaaaa atacaggatt tttagctaaa tggactgact
    18061 tttattattc ctatggttta attgcaggtt acggtggcta tgtatttggt gatgatggca
    18121 caaatccttc agatatcggt ttgaataatg caggtgctgt agaaggaatc tcttatgcaa
    18181 cagattggtt caaaaatgtt tggccaaagg gaatgcaaga cataaaaagt gcaggagact
    18241 tcgccagcca gcaattcatg tccaataaaa ctgcagcaat cattgacggt ccatggcaag
    18301 cgcaaacata caaagaaaac aatatcaatt atggtgtagc caaaattcct actctaaata
    18361 atggacagcc ttatcaaccg tttggcggag gaaaaggatg ggtagtcagc aattatgcta
    18421 aaaacaaaga cctctctcaa aaatggcttg attatgtaac gaatcaggaa aatcaagaaa
    18481 aattctttga aatggtaaat gaaatccctg caaaccaaca agctagggaa acagcaaagg
    18541 ctaaaaacga tgaattaaca acagctgtga ttgaacaata tgaaacagct caagcgatgc
    18601 caaacatccc agaaatgggc gaagtttgga caggtgcaga aaacttgatg ttcgatgcag
    18661 catcaggttc aaaaacacca aaagaatccg cagatgaagc agtaaaaaca atcagtgaag
    18721 ccatagaaca aaaatactga ttaaaatgat aaccgtccat ttttataaaa aatggaacag
    18781 gtgcttcaga taaaagtggc aagagcgaga tggaaaatta tcttgctctt gttgccatta
    18841 tcttaaaagc agtttgcggt ttagcaagtt tagagggggc attcagatgc agcaagataa
    18901 aacaagcaat atcaacgaaa aaaaaatcac gctttgttca cttattccag ggatggggca
    18961 gtttgtaaat ggccaagctt ttaaaggtat cgtttttttc gccatattcg tcctattcat
    19021 tggtcagatg cttctgggcg gatttcatgc attggtagga ttggttactt tgggaagtat
    19081 accaatggaa gatcattcat tatttatttt gattgaaggc actttgcaat tcatcattac
    19141 aatcattttc ttgatttttt acggtttgaa tcttttagac gcttatcgag tagcgaagat
    19201 gcgtcaagag ggcaaaaaaa tcaatcggac gatgaaggaa gtcatacata atataggtga
    19261 tgaaggtttt ccttatctat tgacacttcc cgcttatctt ctcatgattt ttacgatcat
    19321 tttcccagtc ctagttacat tgttcactgc atttactaat tatgacttca atcatattcc
    19381 accagccagt ttaattgatt gggtaggggc taaaaacttt tttagtatct tctttttaag
    19441 ctcatatcgt aatacttttt ttgcagtctt ttcgtggacc gtgatttgga ctttatgtgc
    19501 aacaactttg caaatcaccc ttggtattct cacagcggtt gttgctcacc agaaatttat
    19561 taaattcaaa cgtattttcg gtatcatttt cttattacca tgggcggtcc cagcttttat
    19621 tactatcatg agtttttcga atatattcaa cgatagcgta ggtgccatca atactcaagt
    19681 gattcctttc ataaaccagc ttccttttgt agatatcagt gcaatctctt ggaaaacgga
    19741 cccgaactgg acgaaagtag caattatctt agtgcagggc tggttaggat ttccctatat
    19801 ctatgtgatg gttacaggaa tcttacaatc gatttcagaa gacttatatg aagcagcaaa
    19861 aatcgacgga gcaaatgcat ggcagcgctt ttcaaacatc acgcttcctg ctgtcttcct
    19921 agtggcagcg ccaacattta ttacacagta tacggggaat ttcaataatt tctccatgat
    19981 ctatctgttt aacaatggcg gtcccggaag cgtaggcgga ggagctggtt ctactgatat
    20041 tcttatttcc tggatctata aacttacgac tggaacttct ccgcagtatt ctatggcttc
    20101 agcaatcacg ttgattatct ccgtcatcgt tatctgtgtg tcattgctgg tatttaaaaa
    20161 gacaaatgcg ttcaatatgg gggattaaca atgaaaaaat ttcattcgag tgctcgattc
    20221 caaaaacgac tttctcactt ttttacttac ttttttcttt taatactgtc agtcattatc
    20281 atctatccgc ttttgatcac agcaagtact gccttcaagt caggaaatat tgcagctttt
    20341 agtttagatc tttcaagtga ctggacttta ggaaacttta ctcggctatt cagtgaaaca
    20401 ctttacggga cttggtataa aaatacattg atcatttctg tcctaacaat gatcgtacaa
    20461 gtgactgtag taactttggc gggctatact tatagtcgct atcgttttat cggccgcaaa
    20521 tcaagtttga tgttcttttt agtgattcag atggtaccga ctatggcagc attgactgcc
    20581 ttttatgtca tggctttctt attagaagcg ctcgataagt actggttctt gacaatgatc
    20641 tatataggcg gtggaattcc aatgaatact tggctgatga aaggatactt tgacactgta
    20701 ccaatagatt tagatgaatc tgctaaactt gatggggcag ggcatttcag gatttttttc
    20761 cagattgtat taccgcttgt caaaccgatg ctcgccgttc aagcattatg ggcttttatg
    20821 ggaccttttg gggatttcat gttagctaag ttcctgcttc gaacacctga aaatcagact
    20881 gttgctgtcg gcttacaaac atttatttct gatgtgacaa accaaagagt ctctcttttt
    20941 gctgctgggg caattttgat tgcactaccg atttgtctat tattcttctt tttacaaaag
    21001 aactttgtta ccggcctgac atctggcgga acaaaaggat aggagcagag tatcatgcaa
    21061 acatttccgt taaactattt ttccgcatta cgtacgccaa ctcaagtgtt tgcgggacgc
    21121 aaactattat catggcctaa atttttcttg atatttgtat ttttagtttc cttgatggtc
    21181 atgcctgtga ctctttttta tgccaatcag atccaagcga ttccattaga acaatttcta
    21241 tccgttcatt cgctgatcga tgaacaagga acccaaaaat tttctgaact tgaattatct
    21301 gaaactgggt tacaagcatc gcaacaaacg atagctgtga cccctgaaat tttggtaggt
    21361 gtgtctttat ctgagaaaca acaatccgat catggaactt ttattgattt tgagaaggaa
    21421 caatgggtga tccaacaaaa ggataaatct ggtatacgcc gctatacgat gaattatagc
    21481 ccatctttcc aaccagattc tgtacgtacg cccgaagatt tccaacgatt tttagaaaga
    21541 gaattttatg ccagtaatcg tccaacaatc attttatctt atagtttaag tcttggtctt
    21601 gtcctatttg tcatgacgag tctcatttta ttcggggctt cctttttctt gtggatgaca
    21661 agaaaaagcc aactttcatc cattcataca ttcaaagaga gtgcaaattt gatgctgaat
    21721 gttatgggaa taggttccat ggcagcagca gttgtagggt ttatccactt tgactttatc
    21781 ttgatgctaa gtgtccaaac aacgataact gtcttgctgc ttttatgggt ttttgtcaaa
    21841 acaagattca aagataagcg tgtcgaatga caagtttaag cgatttatgc gacaatgaat
    21901 gtgaaaaaaa tgaaaaataa agtagttttt gaaaaatttc tgaaaaaatt aaacttctta
    21961 gttgattctt ttctttttta gtattaacgt aatagggtag tttttttaag gaggaaaatc
    22021 atgttagaga aaactttata caatcaatta ttttcacgtt ctttctcgct ccctgtcgaa
    22081 gtaaattatt gggacggtac aacgaaacaa tacggagata cggacactcc tccccaaatc
    22141 aaaatcaata tccatgaaga aatcccaatg aaagagatta caagtaacgc ttctttggca
    22201 ctaggagaag cctatatgga tcatcgaatc gagatcgagg gaagtatcca agcattgatc
    22261 aacgatgctt atcagcaagc aaacagcttt ttacgaggaa aagattatct aaaatggctg
    22321 ccaaagaaag aaaaacatac gaaacaaaaa aacaaagaag atatccatgc gcattatgac
    22381 ttaggtaacg acttttataa actttggcta gatccaactt tgacttattc ttgtgcttat
    22441 ttcaatacac ctgaagatac gttggaacaa gcacaaatca ataaagtcca tcatatctta
    22501 gacaaactct ttatcaaaga aggcgaaacg ttgcttgata tcggttgtgg ctggggaaca
    22561 ttgatgttca ctgctaccaa agagtataat gtcaaggcaa ctgggatcac actaagtgaa
    22621 gaacaatacg atttgattac caaaagaata aaagaagaac atttagaaga taaatgccgt
    22681 gtattattaa tggattaccg cgaactaaaa ggcgaaacgt ttgatcatat cacaagtgta
    22741 ggtatgttcg aacatgtagg ttctgaaaat cttgaaggtt atttcaaagt ggtaaaagat
    22801 ttattgaaac caaaaggaac agctttgatc catggaatca gccgacaaca aggcggtgcg
    22861 acaaatgctt ggatcaataa atatattttc cctggcggtt atgtccctgg tgttactgaa
    22921 ttagttgata atattacaaa aaacgatttg caactgattg atttggaaag cttacgtcgt
    22981 gactaccaat tgacattaga acattggaca aagaattttc atcaagtcca agatcaagtc
    23041 acgaaagaaa tgggtgattc cttctatcga atgtgggatc tatatttaca agcttgtgca
    23101 gcttcatttg aatcaagtaa tatcgatgtg attcaatatt tgcttgttca acctggaaac
    23161 aatgacatcc caatgcatcg tgcataattg aggcaaaagt actgtttaaa gactatttaa
    23221 aaagaagcta agttttatga tgctccagaa gtgaactttt ttgtctaact tctaggattg
    23281 tctctaaagc ttagtttctt tttctttata ttttcataat aaaagtttgg ttctttaatt
    23341 tttaaacatg acagaaaatt ttttcttcgt tatacttgta atagaatact attttataac
    23401 aaaggggatc gaatcaatga aaaaaactgt tatttatact agtttatttg cagctttgtt
    23461 tttagctgct tgtcaatcaa ataccaatca aggcacatct gggaatacgt cttccagtag
    23521 cgaacagcgc tcttcacagg tatcggactc ctcaacaaaa gcaagcacat cttcgtctag
    23581 ccagacaaaa agttctagtg aagcaagtac tcagtcagat atcaaagtgt ctgcagctcg
    23641 tgcgatcgaa ttgttccaag ataaataccc agatactgca attactagtt tggaattaga
    23701 tagtgattgg ggatcttact tctacaagat agaaggtgtc gatgatcaaa aagaatacga
    23761 agcaagaatt gatgctcaaa atgaaaaaat ggagacagag aatccagaaa ctctagatcg
    23821 agatgaacaa aatggtcaaa agaaaaaaga agatggtctg gatgttgata aattgatcac
    23881 gattgaggaa gcagcaaaaa tcgccgtcga caaagtagga agcggtacgg caacagattg
    23941 ggatttggat aaagatttag gtactactta ttgggaagtc aaagtaaaag acggcaatca
    24001 aagtacatca gtcaagatca atagccaaac aggcgaagta ctgtcaactg aacaagatga
    24061 ttaagaattt cttcggaaaa caagagttga tttttctttt agtcatgata cactagacaa
    24121 aataacttgt ttgaaggagc gatttacttg agtttagaaa cgacctttgc caatcatatc
    24181 tttgccaatc ctttgatgaa tgcatctggt gtccactgca tgactaccca ggaattagat
    24241 gaactggctc attcagaagc aggagcattt atcactaaga gctgtacgat caatgaacga
    24301 aaaggaaatc ccgaaccacg ctattttgat gttcctttag ggagtatcaa ttctatggga
    24361 cttccaaact taggtttttc ttattatcta gagtatgctc ttgcgtatga aaaagtgcag
    24421 gaaaaccaaa atcaaccgtt atttttttcc attgccggga tgagtgtcca ggaaaacttg
    24481 gaaatgcttg agaaaataga aaaaagtggg tttaatggga tcactgaatt aaatttatct
    24541 tgtcccaatg tgcctggaaa accacaacta gcttacgatt ttgaggccac ttatgaaaca
    24601 ctgaaagaag tattcagcat cttttctaag ccgctaggaa tcaaattgcc tccttatttt
    24661 gattttgctc attttgatca gatggctgat atcttgaatc agtttccatt gacctatgtc
    24721 aatgctatca acagtgtggg caatggtttg tatatcgata cagaacaaga agcagtagtc
    24781 atcaaaccaa aagaagggtt cggcggcatt ggcggagagt atatcaagcc gactgctttg
    24841 gcgaatgttc gcgcttttta tacacgtttg aaaccagaaa tccaaatcat tggtacaggt
    24901 gggattcgga caggacaaga tgcatttgaa catctgctat gtggcgcaag catgttacag
    24961 attggtaccg agcttcataa agaagggccg gaaatttttt ctagaatcat aaaagaatta
    25021 acgcagatta tgtcagaaaa aggatatacg tcaattgacg aatttaaagg caaattacgc
    25081 accatttcat agcaaagaga cgaaggtcat gattgatctt cgtctttttt tataaaaaac
    25141 actcgtctgt tcattcctgt gcaagcgtac tcattgtatg ttagacgaac ttgtgggaaa
    25201 ataacagagg caaaaaggag gataatatga atgatgcaac agaattagca aaagagctta
    25261 aagaaaaaga atttagtttt caagaactag ttacggatat acagaaaaaa ataaagaagc
    25321 aaaatcatga attgaatgcg tttgtcgcgc ttgaaccatt cgagagtaat tcccacgagc
    25381 tattgattcc ccagtcagaa aaagggccat tggctggtat cccatttcct ttaaaaatgc
    25441 tcggtcaaga aaaaaaggga tggctagcta cttcaggatc tcgtttattt gaaacacacc
    25501 gagcttctca tacatctaat tatgtgcggc aagcagaagc gataggtcta gttccttttg
    25561 gacaaaccaa tgcgccagag tttggtttca aaaatattac agacccagtc atctatggcc
    25621 cagcaagaaa cccttggaac cttgaatgta caccgggcgg atcaagtgga ggagctgctg
    25681 ctgcagtttc atcaggaatc gttcctttag ctggtgctag tgatggcggt ggttctatta
    25741 gaatacccgc ttcgttttgc ggattgattg ggctgaaacc ttcgcgaggg acgatgccag
    25801 ttggtccata tgcttggaga ggatggcaag gagctgctat tgatttcggc ttgacagttt
    25861 ctatgagaga cacggaggct ttattttatg ggatgagaag tatccattcc ggtgcgccat
    25921 atcaagtatc gccagttgag tggcaaacac atccaagaaa aaaacggttg aagatagctt
    25981 tttgtgttga ttcaccgatc cactcacaga ttagtgaaga ggcagtactt gctgtaaaaa
    26041 aagctgtaga tttccttgga aaagaagggc atgatttgac agagattcct tacccactag
    26101 atggtcgtaa actgatcacg tcttattatc agatgaatgg cgcagaaaca gcagcaatga
    26161 tccgctcgat tgaaacaggc atccagcgag ctgtcagaaa agaagaactt gaacccattt
    26221 cttggacttt gttccaatat ggtcagaagc tctctgccgc tacttacatc gattctctgc
    26281 atgtatggga tgaagcagca attgtcatgg aaaacctaca tcaagaatac gatatattcc
    26341 tttcaccaac gactgcattt accgccccta aaatcagcga agatttgcaa agtgatgcga
    26401 taagagcaca gatggaacac atcagtgatt gttctgaagt agaaggttta gacgttgttt
    26461 cttccatgtt tgaggagagc ttgaagatca caccttatac acagttggct aatctgactg
    26521 gacaaccagc aatcagcttg cctactcatt tgacaaaaga aaacatgcct ctaggaatcc
    26581 aatttatggc tgccagagga agagaagatt tgctatttca aatcggctat ctatttgaag
    26641 caaatcatca gttccattta ccaaatccat ggaaatagca gaaacaagga gaagaagaat
    26701 gaagaaaaaa gattgtttgc tctaataact agtgcctttt ttattttaag cgcttgcggt
    26761 acagctgccg ctaatcagga agataacagc tggagtaatg tagaaaaaaa gaaagaatta
    26821 gtagtagcga cttctggcac actgtttccc gcatcttatt ataatgatca aaatgaatta
    26881 gttggttatg atgtagattt ggcaaaagag gtggctaaac ggttaaatgt caaaatctcc
    26941 tttaaagaat acaacgtgga tggacaaatc acttctgttt caaaaagaga atcagatttt
    27001 gctgcgaacg attttggtat cacaaaagaa agagaaaaaa aattctccct ttcagagact
    27061 ttcaaatatt catttgacag tatgatcgta cgaaaaaaag atgattcagg aatccactca
    27121 cttgaagatc ttaaagggaa aaaagcagct ggcgaaccca atactagcta tatgcgttta
    27181 gcggaaaaac acggagctaa attagtcaca tatgacaatg ccacgaatga tcagtattta
    27241 agcgatgtag caaatggtcg aacagatgtt attctaaatg attattatct gcagaaaatg
    27301 gccgtatctg ctttaccaga tatccctgta aaaatactgg agaacgttta tttcaatgaa
    27361 aacgaaagtg gttttttatt gaaagaagga aatgatgctc tgaaaaagaa aatcgatggc
    27421 gtattaaaag agatgaaaga agatgggacg acaaagaaaa tatctgaaaa atattttcaa
    27481 actgatgttt cagtcaaacc gaaagaaacg atggctgagt cggtgagtga gtgatgtact
    27541 ttcctctaat tgatttttcc ctcatgtgga cttcacttcc tttcgtactg caaggcttgg
    27601 tatacacatt agggattggc ttcgtgtcgt ttcttttagg aaatctggta gggttgcttt
    27661 tgacagtttt aggtcttttg gattggctgc ctctgaatgt atttattcgt ttttatttat
    27721 cgttctttag aggcattccc gcactagtcc tgctgtttct gttatatttt gggttacctt
    27781 atcaattaag tgccttaacg gcttcagtca tctgctttac gattaccagc agtgcattta
    27841 ttggtgaaat ctatcgagga tcactagcag gcgtttcttc aggtcagtgg gacgctggtt
    27901 tagcttctgg tttttctttc tttggggtat tgaaatatat cgttttgccg caagcttttc
    27961 gaatctcagt accggcactc agtaacgtag ctatggatct agtgaaaggt acttcgttag
    28021 cagcaacaat cacagtgcca gaaatatttc aaaaagcaaa gatcataggc ggtcggacat
    28081 tcgattattt ttctctctat attttagttg cactgattta ttgggtcatt tgtatcggga
    28141 tcgaaaaagt gcaacagtat ttagaaaaac gttctatgca tcagtcaatc tgaaaaatag
    28201 aaatggtgct agcgtggctg gcaccatttc tattttttgt ttcttgtata ttctgcctag
    28261 tattttaaaa ccatttcatg taaaatgtaa atcgaaaata tgttcggagg tagaaaacat
    28321 gaagaccccg ctaaccatcg aaatagaatc ctcgttatac caatattgca tcgagcaagg
    28381 cggcttggtt gtagaagaag tcacgatgcc tgatgaccaa ggaattgtag atacgcttag
    28441 ctgcttgaca aaatttgatg gaagccgaga atggcgatgc tatgagctga aagtgacaaa
    28501 agcagatttt cgctctacag ccaaactgtc atttgttgga cattataatt attttgtttt
    28561 accaagtaaa ctatatgaag aagtaaaaac tgaaatccct acaggaatag gtgttttagt
    28621 gtatcgtccg tacacggttg aagaggagat gcctgcctct ggtacatttc tgattgcgaa
    28681 aaaagcagca aagaaagagc ttgctgtacc ggaagaagct ttgacaaacc gcttcatggc
    28741 ttctttattc agggaagtaa gaaaagcaaa gcaaatggag cgaggcgtaa aatattttcc
    28801 aacagatcaa ttgtacaaag aattgaaaag acgttcagaa aatcaagatc cattttctaa
    28861 cgaacgatat tatgaacggt ttttagagga aatagctagt caggcaatca atgagttgca
    28921 agaagaagtt atcgcgcttc agcatgatta tgaatatttg aggcaacaac agcagatccg
    28981 tcggttgcct acagagccat tggagtgaaa aatatgtact atccttattt aagaggaaaa
    29041 caatttgacc tattagcatt aaaagaagca ctgtcgcgag gattgctctc caataaaatc
    29101 caaccagtga tcgaaccagt acgtgattcc gctacgctta aaaatgtgat cgaattattt
    29161 caaaaaaagc accatccaat cgctgtgatc caaaatcccc aagtaggaca attcaaatta
    29221 ttcgatcagc atgtgcacag ttggacagtc aaagaaaata gctctgtcgt ccctgcacag
    29281 atcttaacgc cagaaaatct cagtgaagta ctggattcac ctccagcgtt tcttgttttc
    29341 gatggacagc actacccaaa agatacagag gtgtggaaac agttggcagg agttgattcg
    29401 aaatttttga taccagatac tagtcgcttt cgcatctggc tgcccgaaaa caaaattgtg
    29461 atccgtgact cttttcaaac gagaaagcat gttgaaagtt atgcagataa aacagatgac
    29521 ttttttagtg atgactatct ttttttccac gcagacggat atattggatt ttctgatttc
    29581 acgatcgaag gtagccgtta tttcgataaa gggttcccta gccgagcgct tgctatccat
    29641 ctaacgtata ttgatgctta cggcaatata cgcgtgaaac attttgtctc tgacagtaac
    29701 gactctgcta aagaccaagc attgaagttt cttgaagcag gagataaaat gaaaaaatgg
    29761 atcatgcgtc accatcatca actcttgatt acttcaggaa tgattgaatt attggctctt
    29821 taccagcaac aaaaattccc tggactggga gtgttgaaaa agtggtcact tatgcatcat
    29881 ttggaactta ttagtcacct gctagatcat ccaaaagatt ggcttaaata ttattcaaaa
    29941 gttcaggaac tatatgaagt gatccaatga ttagataatg taaatgaaaa aggaatagaa
    30001 aagaggaaac tggatgtata ttcggcaaac aaggaaagaa gaagtagaag aagtggtaga
    30061 aatcattaat gccgcagcgg atttcattgc ttcgcaaggc tctcctcaat ggcaaaacgg
    30121 gcagaaacca acaaaagaaa cgattttgaa cgatattgaa agaaaagaaa gctatgtatt
    30181 aatagtggaa gatcaaattg ctggaacagc tgcattagtc tcaagcgtgg atcccgttta
    30241 cacaaaaata gatggtagtt ggaaagaatc aactggtcct tatttatcga ttcatcgtgt
    30301 cgctttagca gaaagtactc gaggaaaaaa actagcaaaa ccgttcttag aacatttgtt
    30361 gacgattgca gccagcaaaa atatccaaga tatccgtatc gatacttatc cagctaatga
    30421 accgatggaa aagaccatct attctgctgg attcacttat caagggatga ttgaatttcc
    30481 ttttgaacac ggcgaaagaa aagcatatca aataatcatc aattgactat aaaatcatct
    30541 gagcaaagat aaagacatta acactactga aaaaaacaat catatgatag ccaagaggtt
    30601 gtaacagaag tggccagctt caaaaaacaa gaaagaattt ccgaaaatgc ttctcaaatt
    30661 tttgtggaat tttagcgtat tttacgaaat agctgctttc tgaaactccc ttcatcgaga
    30721 ggtcgtgaca tagcttttgt cacgacctct cggcttatcc tacgagtatt attcgataca
    30781 tttatatcaa taatcctttt tttattttat ctgcagcttc ttggaacgct ccatcgtttg
    30841 acacgactaa aagtgagggg atagctttca aacgtttcaa ctgtgctaaa tcttctacat
    30901 aaaccgccag tctggctgaa atctgttcag atgaatctcc acgttttttc aggcgcgatt
    30961 gcaatgtttc tttagagatc gtaataaaga taggacggac taccgtcccg aaatactcat
    31021 ataaatgcca aaaaccattt gctgtcaaaa cggcgtaaca atttcctact gtcagtttct
    31081 ttttaatttc tgctttactg gaaccatatt tatgttgagc atattggtcc cactctgcaa
    31141 actcatttcc cttgatcatc tgattgaatg tattgtcaga aacaaaataa taatcctctt
    31201 gatctttttc cccaggtctt ggtgatcgat tcgtgtaagt aatgatcttt tgttccggct
    31261 gaaaaatagc ttctgcgagt gaagtttttc cagaaccaga aggaccgata aatacatagc
    31321 aataattcat tgtcatttct cctttgatga ttgaacaagt gaaaaagctt tggaaaatat
    31381 ttccaaagct tttaaaagta actttgcttt tttgtatatt ataccagcaa gccagtcaca
    31441 atagcactta aaaagctgac taaagtcgct gttagcaaaa ttttcaatcc gtgttttgcg
    31501 acaagatttc ctttttcttc atttaatccc ttcatcgcac cagaaatgat cccgatagaa
    31561 gagaagttgg caaatgaaac gaggaagaca gatataattg ctgttgtacg ctcagtaaaa
    31621 tggaaattac catttgctaa ttctgtcata gcaacaaatt catttgtaac cagtttagtc
    31681 gccatgatac taccggcatc cactgcttct ttccatggga ttccgctgat gaaggcaaga
    31741 ggggcaaaga tgtaacctag gatctcttgg aaagtgatgc cgaatatccc gtggaagata
    31801 gcattgatca tggcaatcaa agcaacaaaa ccgataagca tagcagcaac cgtgatcgcc
    31861 acatggaaac catcaagaat gtattctccc aacatttgga aaaatgtctg ttctttgttt
    31921 tcttcaatga tcagctcatc ttctttttct tctaatacat agggatttac aattgaagcc
    31981 agaatataac cgccaaataa gttcaaaaca agggcagtga tcacatattt agaatcgatc
    32041 agtgccatat aagatccgac gatcgacata gaaactgtag acatagccga tacactcatg
    32101 gtgaacaaac gtttctcaga taggaagggt aattcctttt ttatggaaat aaaaacttcc
    32161 gattgtccta aaatagcaga agctactcca ttataagatt ccaatttgcc catcccgttg
    32221 attttactta atcctagacc aacagctttc ataaataatg gaagaatctt gatatagcgt
    32281 agaataccga taatagcaga aataaataca attggcatca atacggaaag aaagaaaggt
    32341 gcacttcctt tatttgctac accggcaaaa acaaagtcaa caccttgccc agcaaaagca
    32401 agaagatgat caaacatttt tgccaataca gaaacaaccg ctgtaccaaa agttgtacgt
    32461 aataatacga aaccaagaac aagctgtaaa acgaacatca caattagtgg tttcaatttg
    32521 attgcttttt tgttactgct gatcaaaaaa gcaagcccta atgtgacaaa taaaccaata
    32581 atacctaata aataactcaa ataatcactc ctattccaaa ttccgtttta ttttacctgt
    32641 tttgcaaata aaatactaat ctttagtgaa attttcatta cttttttaga gtgaaacgca
    32701 ttcattttcc attagaaaat aaagcgaaca aaataaaagg tttaaaaagt gtaacgtctt
    32761 agtaaagtct ataaaaaaac gaaactatcg attaagctaa tagtttcgtt ttcaacattt
    32821 ataagtaaac tttttctatt ggtaatatag attttcggaa gggtagacag gtgcgcaggt
    32881 aatatcgatt cctagttttt tcaatgtttg ttcatcattt ttattgacca tcacagtaga
    32941 gtgggcttgt gctccctcaa gttcagctag tttatcataa gcaacttgag cgattggatt
    33001 cgttactgca ctgattgata aagcgatcaa gacttcattg atgcttagtg catccaaaga
    33061 ggaatgaagt gtctttgatt tcaatccttg tattgtttca agaactaatg gtgacaataa
    33121 aggaatgtca tctgcgatat gggctaaatg ttttactgca tttaagataa ctgccgctga
    33181 cgcatccatc aatgaacttg tacgcccggt aatgatgact tcatctggta attcgattgc
    33241 aatcacagca gaaggatctt ttgtaggact ttgcgcttga atcttatctg catagtcatg
    33301 ggcagggact accacgtttc ggtcttcagg acgtaaaccg acttcttcca taatcagttt
    33361 gattcgatta actgcttctt cgtcgatcaa tccttttttg aagtcgcatt ctgtttggaa
    33421 ataacgacgg atgatttctt gtttagaggc ttcttggaca acggtatcat ccacgatccc
    33481 aaatcctaca cgattcacac ccatgtcagt aggagattga taaacagatt ctttaccagt
    33541 aattttttca ataatacgtt tgattacagg aaatgtctca acatcccgat tatagttcac
    33601 agctacttta ttgtaggcat caaagtggaa ggaatcgatc atattgacat cttttagatc
    33661 gactgtggct gcttcataag caatgttcag cggatgtttc aacggaacat tccatactgg
    33721 gaaagtttcg aacttggagt aaccagctgc atgtcctttt tggctttcat gatacagttg
    33781 gttcaaggaa gtagcgagct ttccacttcc tgggccagga gctgtcacta caacgattgg
    33841 tttagttgtt tcaatatact cattttttcc aaaaccatct tctgagacga ttttttctac
    33901 gttgactgga tagtcttcga tttctgagtg tttatagacc ttgatgtttc gtctttctag
    33961 tttattgata aagactttcg tggcaggctg tccactatag cgagtgataa cgacactgtt
    34021 gattaataag ccataaccac gtaattcatc gattaaccgc aagatatcca tatcataagt
    34081 aatcccataa tcaccacgga tcttattacg ttcaatatct ccagcataga cgcaaatcag
    34141 tatttcagct tgatctttca atttttgcag caatttgatt ttcgcatctt cttcaaatcc
    34201 tggaagtaca cgtttcgcat gcttgtcgtc aactagcttc ccaccaaatt ctaaatataa
    34261 tttgtcatag tggttcactc gttccaaaat atacgctgac tgctcttcaa tatatttttc
    34321 tgaatcaaaa ccaatttttt tcactaggtt ccctccttaa gtactaaagc attttttcat
    34381 ttttttgagg attcgtcaac tggaagagcg aaattcctca aaaaaacaaa gaaaatggtt
    34441 taaaccaact tgtctagata gttattcatt ggtatgatag tttttgataa ggaaggtgct
    34501 acatgaaaaa aagacagaaa aagaaaaacg catataaaca ctatatccgt tcgattttta
    34561 ccggttatga aagaatgctt gaagatcccg aattggaaca attgacgttt acttatctaa
    34621 acgaagaaac gcagctaact cgtgatgagc atcagcgcat tcatttcaca acaagagatc
    34681 tgcctagtaa ataaaaaata agataaaggt catcggattc gattctgtcc tatcagatgg
    34741 aaagactagt tgatcgaaaa aaaggctgta ccaaattttg gtgcagcctg ttttatggag
    34801 cattgcccgc tcttttttat aacaattttt tacagaaaat ggtactattg aagtattaat
    34861 aagtgaaaaa cagatgagta agaggaggca agtagtatga aagagccaga tacaaatgca
    34921 aattatgagc cagacgaact agaggagacg aatgcggatc aggatacagg acaagaatcg
    34981 tcttcttttt acgatatcaa agaaaaagca agcatgaatc tttcccaatt attagaagac
    35041 ttacaggctt ttgaaaaagc tgtccgcgaa gaagatatcc ctgagatcta ccgtttatac
    35101 aatggccgat tgaatgaaga attaaaaaga agctcaaatg aaaatcacga gatcgatcaa
    35161 ttgctgatgc gtaagatcca tgatcgtttt ttacaggaat ttccttttat ggaacaagta
    35221 gaaaacatct cgccaacgat gagctattac aaaatcggca cttattacca tgatcggccc
    35281 acggtcggta ttgatgcaag tctgccagaa atttttgttt tgcctaagat cgatgaagag
    35341 tgggagaaat attcccaacc ggagtcaacg gactatgaca aaaaaatcaa tgagctagac
    35401 gcaaaggtga tcactgctca gacagaaatt gaacgtttag atgaacaaat aaaagaaatc
    35461 aatcgacaaa tgactgattt gaacgacaat aaaggattct tgaatcgtaa aaaaatcgag
    35521 gaagaaattc aagaattaga gaagaagaag caagtactat ctaatgaaaa attaggctgg
    35581 cttccttata ttgagacgcc tgaaacaatc cagcagcaaa aagaagcatt gaagcaagaa
    35641 gcaagagcag accagcttcg tgcagccatc gtagaaaaag aacaaaggca aatcagacgc
    35701 tatttcggta gcaaagaggg attcggtcaa gcaatccatg aattcttgat gaattatctt
    35761 ggcaatgaga atcctaataa tcaatctaat gaaggaggtt ccgagtatga atgaacacga
    35821 tgaagcagaa tggacaaaaa atgaagaaca aacagaagat catgaagaaa cgaacacttc
    35881 attggaagaa caaacaagta atcctctgga tgacacagaa gaaatcccta tgctagagga
    35941 aacaaaaata cacgaaaaag aaaaagtaac tccgacgaat acgaatactg cagaaaacac
    36001 ccatgcttac gaaataactg aaaatcccgg gtatttagaa ggaaaagagc aagatcatca
    36061 agatatcgtc agtttgattg aaacagcgga agcagaatta gcggatttac gtatgagaaa
    36121 agatttgatc gaatcagatt ttccacaatt attagaatca tatgatcgtt ttatattgaa
    36181 tgaagaacca atctccacga tcggaaagac aagcctgatc gaatacttca cgtatgaatt
    36241 actgaaaccg ttgaatgata ttggtctgga acggtcaaat tcagcttatg acacatggaa
    36301 aacaagacat ttttcgatca attatacgtt gaatggacaa aacgaattag tcttttcctt
    36361 tgtattaccg accatcgatc aacgatacca agtggaatcg atgagtctcc taaacgtatc
    36421 accagagaca atggaaatca atgtccaaga tgaccgggtg ctttctttga tccgacactg
    36481 gtcagtggat cgagtattct ctgcagggca gatcacgata ttcaatcaca aattgaatca
    36541 attattagcc catgcaagaa cacttggttt taccgttaat cagacattac tagacaatac
    36601 gaagccactt cgtttgaatc ttcagagcga atttgaattg acgaatgaag tattggatga
    36661 tatttttatc gtggcaatga aaaatccatc ctacgatatg gaaaagatca acgaaactac
    36721 ttatcaagta cgattagata aaggacagtc tttaacgata acaacaaacg aaaaagatca
    36781 aacagtcttg tcgatctcat ctggagacta cccacgatct gtcattgatt tctttatcaa
    36841 ttacgaattc ttggtcccat taatggtgag aaagtcctga ttggataagt tggattacca
    36901 gatgtcattc agataattct gttccaaagg acttgcggca gttatccaga ataattgtca
    36961 caagtctttt ctgtatgtac taaatggacg tgaataactt gctgatgaag gagggatttc
    37021 attaggaatg tccacaaata aaatagcaca gcttagctta ttgtctgctg cttgtgtagc
    37081 aggtaggatc gcttttcaat ttattccgaa tttccagcca atgactgcta tttttttatt
    37141 tatagtactt tacttaagct taaaagatgc gttaattgtc atgagtcttt ctattgcgat
    37201 cagcagtttt tattttggtg ttggaccatg ggtcatcggc caatggatca gctatactgt
    37261 tgttctgagt ttgttttcaa tcgtctgctt gagaaaaaca gtgcaaagga atctatggtt
    37321 aaagggagtc tgtttttttc tggcgggcat ggtttacgga ataggtatga ccgtttttga
    37381 tacgctgtta tatcgtttgc ctcaaccttg gatctattac cttcaagggg tgtcgtttga
    37441 tttgatgcac agtataggca atgttgtgtt ctttcttgtt tttctgccag tcgtcaaacg
    37501 tttttacaat cattcaggag gaaaaaatga aaaaaataat ttatagtttg cttgcaatga
    37561 gtgtcagtat actcattttg acaagttgca gtacaaccta tacacaatcg gcttccaacc
    37621 aaaaggagga agtaaaaaca tcgcaaaaag caacaatcac gttacaagaa aatggtcaaa
    37681 acttttcgga aaaagaagtg ttcttcaaaa aaggcgatga tttactgagt attttgaaac
    37741 gaaattttga agtcaaagaa gataacggct tcatcacttc gcttgaaggg cactcacagg
    37801 atgagaaaaa tcaactctat tggatgttta ctgtggacgg gaaaagtgct actactggtg
    37861 ccaaagagat caaattgaat gatggacaat cggtcatttt caatttgtct aaactataag
    37921 tttcataaaa aactgttaaa gggcgaatat tgccataatt cagtgagttc agttgatgaa
    37981 agaaggaaaa taacatggaa aattttaaaa aaagcggaat gttttccgta attgctgctc
    38041 taggggctaa tattctagtt gctatcagca aatttgtcgg ctatgcaatc agtggcagtg
    38101 ccgccatgct aaacgaaagc atccacagta tcgttgattg cagcaatcag attttgctgt
    38161 tattcggtga taaacaagcc aataaaggac agagcgagtt gcatcaattt ggtgaaggac
    38221 gagcaaaata ctttttcagt acaatcgtcg caatgatgct tttcttcggc ggtggggcac
    38281 ttggggtgat ggaagctttt gaaaagttga cgcatccatc ccatgaagtg ggtaatccga
    38341 tcattgttat agcaatactg ttatttggtt tggtaatcga aggaagttcg ttacgcgtgg
    38401 caatgaaaga aatcaaagaa ttgaatactg aaaaactttc cacgatgcgc tttttgcgcg
    38461 aaagtcgaca cagtgaaata ctgattattt ttacggaaga cttgtgtgct gtaatcggtt
    38521 tggtcttggc tttagcagga acaatattga cttatgcaac cgggattgct gcatttgatg
    38581 cgatcagcgg attgctgatc ggtttcttgc tgatgggagc cgccattttc ctagcaaaag
    38641 aattttatag tctgatcatc ggtgaaagcg tgacagcaag cgatttatca aaaatcaagt
    38701 tagcttttga acgtcctgag atcagtcggc tgatcgatat aaaaacagtt catttaagtc
    38761 caacggagat tttagttgca gcaaaagcag atatcgttgg taacaaagag aatgaagctt
    38821 actcggtcat caatgatatt gaaaaaaata tgcgtcagtc tcttcctgac aagaagatgt
    38881 atatatacat tgaaacagat aaatatgacc caaattattc tcgtaaataa aacgtttatt
    38941 catgaattga agcaaaaatg agaaaaatat aatcttgttt ttaaataaaa cggctacaat
    39001 ttagcgaatt tatgttacaa tgagtccgct gtttatttgt tgtaattaaa ggagatattt
    39061 taatgaacaa aaagaaaagt gcgccatggc ttcaagcttt gcatgcagtg atgccacttt
    39121 gtataagcta tataccagta ggattagctt gcggagtatt gttgcaaaaa gttggatttg
    39181 atcctctctt atcaggactg ttatcgattc tggtcttttc cggtggcgcg cagtttttag
    39241 ttgcatctat gcttacgacg caagcatcat ttgcaacgac attattgatg gttttctttt
    39301 tagaattacg ctatacatta ttaggagcaa gtcttgccgg ttttatgaaa aaagaaaagc
    39361 ggacgttttt ggctgtcttt tctcaatcac tgaatgatga aaactatgcg gtgaactact
    39421 taaagttttc aactgaccct tcctggaata aaagaaaggc tttatatgtc aattggttct
    39481 caatgactgc atgggccggt agcaatatga tcggtaattt tttcggctcg gtgattcgag
    39541 tagatgctga ccttgtccat tttgctttga cggccatgtt cattttcatg tttatcatgc
    39601 agatgaaaag cgcactactg atctttacag gtttattctc aggcgtatta ggggtcgtat
    39661 tcatggtatt attccaaaat actttcggat tgattgcagc aacagtcatt gcttcatttg
    39721 ccggatttat gctggagaag gcattcaaaa aagaaaaagc taagaaacta agagaccgcg
    39781 gtaaagatgt caatgagccg ctcttcaact tcccggaaca ggaggccaat caccatgact
    39841 aaactatatt tgctactttt agttgcttgt ctgttcatcg tggcatatat cccgcgcttg
    39901 ttcccgatgc tttattttac tcatcgaaaa gtgccatcct ggttcagtga ctggatgaaa
    39961 tatgtaccgg tggcattatt tgcggcgtta gcttttaaag atgttttcat tactcatgaa
    40021 catctggata ttgcttggaa tatcaaaata gctgcaatga ttctagtagc aggcgtggct
    40081 tacaaaacac gttcgatggc gttgtcagtt ttgacaggac ttgcgtctgt ctttttgctg
    40141 tctatgcttt aaactgtttt attttattaa aaacagagat tgcgacataa gttgttcaaa
    40201 ctgatctatc cgaactgcat ttgcaacagt caattctgga tgcaagttta ttcgtaggga
    40261 taaaaaagat tagtgttggc ttatgatgca agctcttttt tattttagga attagagagg
    40321 gatttgtcct tctatgattt tttgctataa tagggaagat gtttatttta tgaaagaata
    40381 gttgagggaa tttaaatgaa taaaaaattg atgcaaggaa cattttggct aacctttgct
    40441 aatcttctat gtaaagtttt aggggtagtc tatttgattc cctggctaag tatgatgggg
    40501 aacaatcaag atggtatgct tgctacgaca ttgtataatg ttggctatct tccttatgga
    40561 ttgttcctga tgcttggtac agtcggattt ccaaatgcga ttgcaaaaaa agtagctgta
    40621 gccacaaaag aaggagataa cgctgcttgt cggctgattt ttagaagtac gatcaatatc
    40681 atgtttgtca tcggtatcgc ctctgctgca ctgatgtatt tatttgctcc tttactagcc
    40741 ggaatcagtc cgattgctaa cgttaataat gggatactag ctatcagaag tttatgccca
    40801 tctttgattg ctatcccaat tcttagtgca atgagaggat atttccaagg aaaaaatgat
    40861 ctgcggcctt atggaacttc tttgattatc gaacaggctg tgcgagtgat cgttatcttg
    40921 gctggtactt attacttgcg cgtattgact gacggaacca tattagaagc tgtattgatc
    40981 agtacagtcg cttctttctt cggtgggtta gctgcgatta tccatatgta tatcgtcgga
    41041 cgcagaaaag acttcttcga acttaaagat tttttgattt ccagccgtta tttcgaaaga
    41101 gaaaaccgat ctgcctctgt ctctatcatt cgggaaacac taccgtttat ttttgtcggc
    41161 tcagtcatta ctatcgttca aatgatcgac caagtaacga tgaaaccact gcttcacttt
    41221 ttccgtccag agatcgcaga tcagcaactg gaattcttat tcagccgtgc ttctgtcaat
    41281 ccaaataaat tgacattgat cctgatctcc atggtaggaa cagtagctat aagcagcttg
    41341 ccaatattaa gcacgatgaa gaaaaaagat cggatacaaa tcgaaaaaac agtaggagat
    41401 agtttttcga ttgcgttatt gattcttctt ccttcattga ctggaatgtc tttattagct
    41461 ggaccactat acacattgtt ttttggctat gatcctgaaa gtgtcggata tttccaaatg
    41521 gctttgctag cttctttgtt tttctcttta ttcacgatcc tatctacgat gcttcaatct
    41581 ttgaatcacc atcgttttgc gatccgatta actgtagaag caattatcct gaaagtcatc
    41641 ttccaagtaa tcggattagg attagttggc ggatacggga tgagcttatc aaatggctta
    41701 gcattcggta ttgtctttgt tcgcggctat cactttatgt gcaaagaata ccgaatagca
    41761 cctttagcaa agatcagcaa ttttttctta aaaactttcc gctccaccct gattatgctt
    41821 gcagtatgtt ttgccgtttt ctttttgctg aatcagcgat tgtcaatgga atcaaaaagc
    41881 tatgcaatga tttattgtgt ggctgtagga agtattggcg gcttagtatt tttattttct
    41941 caattcggaa aaaatgggtt tcgaatgttg aaaaatgtta aacatcatag cagaagcaaa
    42001 gaataggtta actaatcgtt ttttgctgtc acttgaaaaa cggcaactcg tatgattacg
    42061 cttgtcgttt ttctattttc caattttagt ttcatatcta atcttactta tgatatagtt
    42121 ataaggtctg gaaaaattct ttgaaacgag gaaattaaac acatgaaact tgcagtagtt
    42181 acagatagtt cggcatatct gccggaacgt atcaagaacc atcccgactt attcgttatt
    42241 ccaatccctt tgattatgga tgggaaaatt tataacgaag gaatcgatat cgaagcggat
    42301 gaatattatg gacttttaaa aaacagtaaa gattttccta ctacttcaca acctgtcgta
    42361 ggggaagttt tgggtttata tgaggaattg aaagagaaag ggtatgacac gattttaagt
    42421 atccatcttt cttcagggat ttctggcttt gtcaacacat tatttgcgat gaaagatgac
    42481 atcagcggag taacggtcat tccttatgac tctaagatca ctagtatgcc gatgggacac
    42541 atggtagaag ctgccttaga cttaaatgat gaaggtcagt cccttgatga aatacttgca
    42601 catatcgatc gaatccgaga taatacctac gcttatctga ttgtagatga tttgaacaat
    42661 ttagtacgag gaggacgttt gacaaatggt gcagcgctga ttggcagctt attaaaaatc
    42721 aaaccgatcc tgacattttc tgaagggaaa attgttttat tcgaaaaaat ccgttcaagt
    42781 aaaaaagcat ttgctcgagc tgaagaaatt attggtagaa gaaataacga aatacaaccg
    42841 ccagtcaaac tttacgtgat acatgcaaat aatttagaag tagcgattgc ggagaaagag
    42901 aaattgcaga aaaaatatcc aaatgcagaa atcgaaattg gtcatttcgg accagtcatt
    42961 ggtacacatt taggtgaaaa agccatcggc attgccattt cagcgcaata attcctttta
    43021 ttcaaaaaac ataccaaaaa tattccaaca tcatcttgga ctttctacat gttactaatg
    43081 agcgtgtaaa agaacgagat ggtgttttta tttctatcaa tgaagctctt tttctttgca
    43141 atcctcactt caatcctcta taatgtcgca tatagtttag taaatgagta aactactaat
    43201 ttacttattt actaaaaata aaaggatgag gagttaaaat aatggaaata ccaacaaatt
    43261 taaaacataa accagtaatc gttgtagaag actatgataa agttgatgga agaaatgcat
    43321 taaatacgga tgcaaaaggg ctttcactgg gccttgctca gtggaatgat cgtggaaaag
    43381 tcgatatctc aggcaaggta tggcgacata ctggagaaaa atggtcacga cagtcggaag
    43441 aattaccaat cacacgtatt ttagatttag cgatcttagc tgcacaagga agtttatact
    43501 tccaagatgc ttatcgttat gaaaaatttt atgatccaga aaatccagtc gtagacatca
    43561 ttggattaca agggaaccga atgacggtag aagtagatac caaaaatcca aagatcgatg
    43621 aagacatcat tttgtattac gatacactac aaaaagacgg agaactgatt ggggaacgat
    43681 tccgtatttt aaaacgtctt ttagatgagc taggatatta atagacagag atgatcaaaa
    43741 ggggaagaga agcatggaga atttctcact aacagaaaac cgaacctttt cacggctaga
    43801 aaagcaaatg atctggaaga aaccgaaaag ccatcggaca agtgcagaag aatggcggat
    43861 cgcctccgaa atcaaaggga attggcaaga tcctgaaatg aaaatcagta acgtactttt
    43921 ggaaggagat gccgggtcgg ggaagacaca attagccaaa gcactatctg ctgatctgca
    43981 acttccctat acaaaagtga cctgttttgc agatatggac aaatcagatg ttttcggagc
    44041 cttattacct gtagtagatt ctaataagga acaagaccaa gaattactag aagctattta
    44101 ccaaacagat acacttgaag ctgtactgac actgatccag aaccattacg gcattgatcc
    44161 tttttctgct aaagaaaaat tagcagagct agttcaaagg atcgaagctg attatccaga
    44221 tgcaatccat tacagctatt acccttctga aatcgttcga gcgattgaaa aaggatattt
    44281 attagagatt caagagccga ctgtcatccg agatgcctct gttcttgtgg cacttaactc
    44341 agcgctcgaa ccaaatggga tgttgaattt accgacagga atcattcgtc gccatccaga
    44401 ttgcgtcatt gtgatcacta caaatcgaaa ttaccaagga aatcgcccat taaatgaatc
    44461 tttaagagat cggatgcaac atgcggaaaa aatggatctt cctgccttag aagtcatggc
    44521 agaacgtgcg atggcgaaaa ctatgatcca aaaacaagaa cttctcttaa agatggcaga
    44581 gattatccgt ttgttggatg aaactgcaaa agctaacgcc atcaaaggtg tagcaggaat
    44641 gcgttcttat ttttattggg caaataccta taagcaagga caagatttac tccagtcgat
    44701 ttatccaaaa gttttgtata aattatccac tgattcagat gaattggcaa ttcttgaaca
    44761 agctttgtct gacagtggat tgctactgga acttcaggac atattgagaa aagaaaaatg
    44821 gggtcatcct caatctgagc atacaaaagg aagaaccatt agcgccgaag aagcaaatga
    44881 acgaaacatc actgaaaatg ctgaagaaat tctgcgctta gatgaaaaga aatcgttgtc
    44941 tgctgaagaa ccaaatgagg gagaagagaa acaagaagaa acaatagaaa aaaacgagat
    45001 tcctcctcaa atgcaaaaag aacgcagtag cgatatcgaa ggaaaaaatc aaaaagaaca
    45061 acaaacagga gatgattctc aagaaatgtc tgcttctgac atggaagcac atgataagga
    45121 aatcaagaag caactgaata aagaagcgcg acaaatcatg aaggaaacga ttcatgaaaa
    45181 agaaggtctc atcgttcacc gaccagcttt ccaaggaaaa acgccggaag cacgtgagct
    45241 acacatgcaa gtaatgccaa tagtagaatc acttagccgg caaattttag agttactgga
    45301 taatgaacaa acagagacgt accaaaaagg aaaatacgaa ggtcagcggt tcaatgcaag
    45361 caaagtagca tatggtgatt tgagaaattt tgacaaaaag aacccgccac atgagcaacc
    45421 ttctttagcg gtagctgtac ggatcgatga atctgggtca atgatacggg atgatcggat
    45481 cgaagcggca aaaaaagcag cgattgccat tgccgaattt tctaagaaag tcgatatccc
    45541 attgttgatt tacggagata cagcagaccg ttcgtcaaga gaaaagactt ctttgttttc
    45601 ttataaagaa tttgaagacg gatttcaatg gttaaatgaa aaattagtca ctatgaaacc
    45661 aaggcaaaac aatcgtgatg gtgctgcact tcgtttagca gcagaaaaat taaacagaca
    45721 atccgcaaca accaaactgt tgcttaatat tagtgacggt cagccaaaag cgttgccgga
    45781 ttatacaggc aaaaaagcaa aagaagatat ccagtctgtt ttgaaagaat atgaacgtca
    45841 aggaatccta tttgtctccg cagctattgg ccaagacaaa gaagaaatca agtcgatcta
    45901 cggtgaaagt cgttttgtag atattactga cttgaatgaa tttcccaagc aaatgattca
    45961 actgattgcc cgctatctat gataaaataa agctcaacga acgcacttag cagattcgtt
    46021 gagcttttcg tttctagtta ccggtaacaa ggatacttct aaaatagaat cggttataat
    46081 caagagggac cgttaaagga gtgaaacgat atgatacaag aacaaaaatg gtggaaagaa
    46141 gcagtaggct atcaaatcta tcctgctagt ttcaaagata gcaatggcga tggtcaagga
    46201 gacatcaatg ggatccgtga aaaacttaat tatttgaaag atcttggtat cggctttatc
    46261 tggatcaatc cgatctatca atctccattt gtcgataatg gttatgacgt aagtgactat
    46321 caagatatag aagagagatt cggaacgatg gaagattttg atttattgct aaaagaagca
    46381 catgaattag ggatcaaagt gattatggat cttgtcatca accatagttc ggatcagcat
    46441 caatggtttg aagaatcgaa aaaatctaaa gaaagcccgt atcgcgatta ttacatttgg
    46501 gtcgacgggg tagatggcaa agaaccgaat aattggacat cgattttcgg cggttctgct
    46561 tgggagtatt ctcatgaaac tggacagtat tatctgcatg tttttgcaaa agaacaacca
    46621 gacttaaatt gggaaagcga gaaattgaaa gaagaactat tcaatatgat ccgatggtgg
    46681 ttggataaag ggatagatgg atttcgttta gatgcgattt ctcatgtaaa aaaagatgaa
    46741 tattcagtaa aagccacaga gaaccctttc tcaccctttc aaaatgtctc aggaatcgaa
    46801 gaacatttga ccgatttgaa acatgttttt gaagagtacg atatcatgac tgtcggagaa
    46861 gcaagtggtg tcactgcaga agaaggacca caatgggtag ggaaagacgg ttatttcgat
    46921 atgatattcg aatttgatca tatccatatc tggcagcaag aaaaagaagg gcaattagat
    46981 gtccttaaat tgaaacttgc attaagcgct tggcaaactt cattggatgg tatcggatgg
    47041 aacgctttat atatggaaaa ccatgatgtt cctcgtgccg tttcagtgtt tggagatact
    47101 cgtcccgatt tttgggctat gtctgcaaaa gcaatcgcta tgatgtattt ctttttgcaa
    47161 ggtacgccat ttatttatca aggacaggaa agcggaatga cgaatatgcc ctttgaatcg
    47221 atcgatcaag ttgatgcagt agattcgaaa agactttata aaaggctgct tgcggaaggt
    47281 aagacaagag aagaagcatt ggatatcatt cgtgaaacaa cgagagacaa cagcaggaca
    47341 cccatgcaat ggacttcgga acaatatgct ggtttttcta cacatgaacc ttggctgatc
    47401 actaatccaa ataccaaaac gatcaatgta gaacaacaag aatatgaacc agagtcggtc
    47461 ctgcaattct ataagaacat gatccgcatt agacaaacca ataaaggtct gatatacggt
    47521 tcttataaag aatatcttca tgaacatcca caactttatg tctatgaaag atatttagaa
    47581 gatgaacaat atcttattat ggtaaactta acagaatcac ttgctgacta tgaacttcca
    47641 aaagaagcag atcagtcctg gacattactc ttgtcaaatt cctctagcgg agaatttgaa
    47701 gctaaaggca tactagcacc ttatgaagct cggttatata aaacaaacaa gtaaaacttc
    47761 ctcgttaaag ttcattagtt ggactttgcg aggaagtttt tcagattgct ctgtcaatta
    47821 ctcatttcaa taattcgctc taggaccacc gatatattta ggacgagagc gaagggctgt
    47881 cacgtgagct tgtccaaggg ttttcaaacg aggtctgaca ggtacttgga catgtttgat
    47941 atgcataccg attgatgtgt caccgatatc gataccggct tgtccaacta cgtgttccac
    48001 ttcgacagga tcattgaact ggtcaaaagc agcaacagaa caagcacctc cagcatgtag
    48061 tgcaggaaca acagagacaa tttcgaaatt ttttgcttct gccactgttc gttctactac
    48121 taatgctcgg ttcaaatgtt cacaaccttg gacagctagc gcaatttctt taggatccaa
    48181 caactctttt aacgtacgga tgatccattg accaacttcc gcactggaat tttttccaat
    48241 atgtcctcca acgacttcgc ttgtgctgca tcctaaaaca aaaagatcac cttttttcaa
    48301 gtgtgcctca gccaatatgt cattaactat ttcagtcaat tggtctttta attctttttc
    48361 tgacaacttc attttctaaa accttctttt tcaattaata ttgcttccgt gcttgaatac
    48421 gttgaagact tgcagttata ggaaaggcaa gtcccattcc aatcagattt tggaagatgt
    48481 ttcctggtat agaagccact ccagccggcc aatcatataa aatccaaccg gcgataccat
    48541 agccgatgat cataactaag cttcctaata aaagccctaa tccccacata cgagtagaag
    48601 atttgctgaa agaaccagca acatatcctt gtaacccgtg gatcactaat gaaaaaactg
    48661 cccactgcgg atatcctgaa atcaaatcga tcaatagacc actggaagca ccaacaacta
    48721 atccacccgt tggaccataa agaaaagcag cggtatagat cccggcctcg cataatgtca
    48781 caaatccatt cgtagccggt acagggatca aaattgttaa tgaaagggca actgtcaacg
    48841 caatcagcat agcatagatc gttaattgct tagttttcat ttctcattcc tcctttttga
    48901 ataccgccag accagacact tccggtatga tcgttcatca gcacgccatt agaaatacaa
    48961 tgggcaacaa attttttact ttctgctact gctttggtaa aatctgcccc taacacaaga
    49021 ttcgctgtta ttgcagaaga aaaggcacaa ccggccccgt ttactgttgt agtgtcgatt
    49081 tttttatgag aaaatacctc ataatgatca attgaataga gaagatccac agcttcatct
    49141 ccagccatcc ttgtgccgcc tttgatcaca atgttttttg ttcctgaagc agtgagttct
    49201 ttagcgagat ggatcatttc tgttaacgaa gagggaagag cttgaccaga aagtaaagca
    49261 gcttctgcca aattaggcgt aatcatcgta acaagtggaa aaagttcttc gatgagctgc
    49321 gaaatataca attgattgat cacagcttca gtttctttga atgccaaaac agggtctaaa
    49381 atgattggga tattttgttt tgtttttatg aagtctcgaa caaccatgat tgcttcactt
    49441 gaattcaata acccaatttt gataccatct aatgaagtca ttttatcaat cgaaactaac
    49501 tgtcgtttaa gcaattccaa agatatagat tccagcataa atcgctcatt aatatctagt
    49561 gcccctatag aagtcaaggc gcttagtccg aatagaccaa aattctcaaa agtttttaaa
    49621 tctgtttgga ttcctccacc agcaaatgga tcagaaccgc caattgtcaa gattcttttc
    49681 ataacatttt cctccatgaa taagagtata acgaaatttt caaaaaagaa aaacagccaa
    49741 ttggcatatt tttatctcat ccaatttaaa aaaacaaaaa gaaaagaaag accaaaatgg
    49801 atctttcttt ccttaaata
//
LOCUS       DAXQKX010000017        48168 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.017, whole genome shotgun sequence.
ACCESSION   DAXQKX010000017 DAXQKX010000000
VERSION     DAXQKX010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 48168)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48168)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48168
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.017"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(53..388)
                     /locus_tag="ACF3MF_001040"
                     /pseudo
     CDS             complement(53..388)
                     /locus_tag="ACF3MF_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(563..2698)
                     /locus_tag="ACF3MF_001041"
     CDS             complement(563..2698)
                     /locus_tag="ACF3MF_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HFE3927056.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(2781..4436)
                     /locus_tag="ACF3MF_001042"
     CDS             complement(2781..4436)
                     /locus_tag="ACF3MF_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFE3927057.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(4438..4752)
                     /locus_tag="ACF3MF_001043"
     CDS             complement(4438..4752)
                     /locus_tag="ACF3MF_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFE3927058.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            4922..5182
                     /locus_tag="ACF3MF_001044"
     CDS             4922..5182
                     /locus_tag="ACF3MF_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HFE3927059.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            5196..5510
                     /locus_tag="ACF3MF_001045"
     CDS             5196..5510
                     /locus_tag="ACF3MF_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HFE3927060.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(5995..6549)
                     /locus_tag="ACF3MF_001046"
     CDS             complement(5995..6549)
                     /locus_tag="ACF3MF_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HFE3927061.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(6675..8603)
                     /locus_tag="ACF3MF_001047"
     CDS             complement(6675..8603)
                     /locus_tag="ACF3MF_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HFE3927062.1"
                     /translation="MDNEMISQLQFDRIKKEIQARAIGNYSKKRISDMTVSTNLQTVL
                     DRQEETREARLILESSQHVPFMGLPRIDALTEQVKKGLILQPTDLIEYADFLRSSRMI
                     TKFFDKNQYQTPLLFAYSKHLPDLINVEELIDQKIKNNKVSDDASRNLRKVRKQLQLI
                     EKEIQSKLLKFLRHPKNKEMIQEAMIVQKGEYYTIPIKASYKNKIDGTIIDESNKRTT
                     VFIEPTVISKLNEHYQLLKAEEISEEYQVLAALTGAIAENEEVIDLLIETITVLDIIF
                     ARAKFSREINGSTPRINKSEHIIIKQGRHPFLPEHAVPLDVEIGKDYRGLIITGANAG
                     GKTVVLKTVGLLTLMAMFGMQVPAKEGTELAVFDEIFVDVGDHQNLENALSTFSGHMQ
                     NIAAILKKIKRNTLVLLDEIGSGTEPNEGAALAIAIMESMYEQGALIIATTHYGEIKK
                     FAGDHEDFVPAAMAFDREALRPKYQLRVGETGESQALWIAHKMDMSMKLIHQAERYLA
                     EKAYRTQKKEFLPKTAVTNRKENKKERQLFAKGDRIFVNEYQKEALVYEDIGEDTIDV
                     YLDKKIIHVPRQRVRLVRSAEDLYPTGYDLDSLFIDYKTRKRQRDLERGSKKAHKVLV
                     KEMRKRQEERRVNDENSK"
     gene            complement(8909..9625)
                     /locus_tag="ACF3MF_001048"
     CDS             complement(8909..9625)
                     /locus_tag="ACF3MF_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HFE3927063.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(9626..11449)
                     /gene="glpO"
                     /locus_tag="ACF3MF_001049"
     CDS             complement(9626..11449)
                     /gene="glpO"
                     /locus_tag="ACF3MF_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HFE3927064.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(11463..12959)
                     /gene="glpK"
                     /locus_tag="ACF3MF_001050"
     CDS             complement(11463..12959)
                     /gene="glpK"
                     /locus_tag="ACF3MF_001050"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HFE3927065.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(13095..14555)
                     /locus_tag="ACF3MF_001051"
     CDS             complement(13095..14555)
                     /locus_tag="ACF3MF_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3927066.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(14545..15840)
                     /locus_tag="ACF3MF_001052"
     CDS             complement(14545..15840)
                     /locus_tag="ACF3MF_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFE3927067.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVKEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(16172..16849)
                     /locus_tag="ACF3MF_001053"
     CDS             complement(16172..16849)
                     /locus_tag="ACF3MF_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HFE3927068.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(16879..17970)
                     /locus_tag="ACF3MF_001054"
     CDS             complement(16879..17970)
                     /locus_tag="ACF3MF_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HFE3927069.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(18071..18505)
                     /locus_tag="ACF3MF_001055"
     CDS             complement(18071..18505)
                     /locus_tag="ACF3MF_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFE3927070.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(19089..20546)
                     /locus_tag="ACF3MF_001056"
     CDS             complement(19089..20546)
                     /locus_tag="ACF3MF_001056"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFE3927071.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENL
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIEDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(20543..22438)
                     /locus_tag="ACF3MF_001057"
     CDS             complement(20543..22438)
                     /locus_tag="ACF3MF_001057"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFE3927072.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPITLLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSPVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(22496..24271)
                     /locus_tag="ACF3MF_001058"
     CDS             complement(22496..24271)
                     /locus_tag="ACF3MF_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFE3927073.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARLPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYLVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESSEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(24321..25817)
                     /locus_tag="ACF3MF_001059"
     CDS             complement(24321..25817)
                     /locus_tag="ACF3MF_001059"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFE3927074.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     EIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRIWKEEDCAPVMLDGDEQYLQANTVDYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(26011..27633)
                     /locus_tag="ACF3MF_001060"
     CDS             complement(26011..27633)
                     /locus_tag="ACF3MF_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFE3927075.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESINAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTVPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(28083..29396)
                     /locus_tag="ACF3MF_001061"
     CDS             complement(28083..29396)
                     /locus_tag="ACF3MF_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFE3927076.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCILMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLLGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFMGFMWILNVK"
     gene            complement(29641..29865)
                     /locus_tag="ACF3MF_001062"
     CDS             complement(29641..29865)
                     /locus_tag="ACF3MF_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927077.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(29885..30307)
                     /locus_tag="ACF3MF_001063"
     CDS             complement(29885..30307)
                     /locus_tag="ACF3MF_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFE3927078.1"
                     /translation="MESVYRQERKSNRKKGQTMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGVLTFNFSDPEGNYFVIGKAESSD"
     gene            complement(30449..31159)
                     /locus_tag="ACF3MF_001064"
     CDS             complement(30449..31159)
                     /locus_tag="ACF3MF_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase beta subunit-related
                     protein"
                     /protein_id="HFE3927079.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGDESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(31177..31673)
                     /locus_tag="ACF3MF_001065"
                     /pseudo
     CDS             complement(31177..31673)
                     /locus_tag="ACF3MF_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(31710..32162)
                     /locus_tag="ACF3MF_001066"
     CDS             complement(31710..32162)
                     /locus_tag="ACF3MF_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFE3927080.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(32297..32902)
                     /locus_tag="ACF3MF_001067"
     CDS             complement(32297..32902)
                     /locus_tag="ACF3MF_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFE3927081.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(33352..33972)
                     /locus_tag="ACF3MF_001068"
     CDS             complement(33352..33972)
                     /locus_tag="ACF3MF_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFE3927082.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(33974..34843)
                     /locus_tag="ACF3MF_001069"
     CDS             complement(33974..34843)
                     /locus_tag="ACF3MF_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HFE3927083.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANKAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(34866..35273)
                     /locus_tag="ACF3MF_001070"
     CDS             complement(34866..35273)
                     /locus_tag="ACF3MF_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFE3927084.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDRHKLAELYEQVGLKFSELHENDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(35292..36581)
                     /locus_tag="ACF3MF_001071"
     CDS             complement(35292..36581)
                     /locus_tag="ACF3MF_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFE3927085.1"
                     /translation="MSVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINDQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     ILLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFINATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(36608..36910)
                     /locus_tag="ACF3MF_001072"
     CDS             complement(36608..36910)
                     /locus_tag="ACF3MF_001072"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFE3927086.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(36935..39028)
                     /locus_tag="ACF3MF_001073"
     CDS             complement(36935..39028)
                     /locus_tag="ACF3MF_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFE3927087.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLEEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(39517..40245)
                     /locus_tag="ACF3MF_001074"
     CDS             complement(39517..40245)
                     /locus_tag="ACF3MF_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HFE3927088.1"
                     /translation="MGLCLFALPTQGFAVAGGHGGGTSSGRSSGRGSFGGRSYGGSYF
                     GSRSYGRDSYGYYGPSTGPSSYEQTGFLALAVLSVGGVSAFSIVKNKRQKKRLKSEIL
                     SRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFAEHQKVLQKNKAD
                     GVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLISGSKTQRQYFSQ
                     IWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(40391..41104)
                     /locus_tag="ACF3MF_001075"
                     /pseudo
     CDS             complement(40391..41104)
                     /locus_tag="ACF3MF_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
     gene            complement(41105..43012)
                     /locus_tag="ACF3MF_001076"
                     /pseudo
     CDS             complement(41105..43012)
                     /locus_tag="ACF3MF_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
     gene            complement(43126..44457)
                     /locus_tag="ACF3MF_001077"
     CDS             complement(43126..44457)
                     /locus_tag="ACF3MF_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFE3927089.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRVMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKANFGQLNELVPFGFAGMIASFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKNAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQSGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFVGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(44423..45901)
                     /locus_tag="ACF3MF_001078"
     CDS             complement(44423..45901)
                     /locus_tag="ACF3MF_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFE3927090.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLKNPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(46206..48041)
                     /gene="tdc"
                     /locus_tag="ACF3MF_001079"
     CDS             complement(46206..48041)
                     /gene="tdc"
                     /locus_tag="ACF3MF_001079"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HFE3927091.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEQVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     EQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKEIAKAMEKKLNEIIQ"
BASE COUNT        13760 a        10358 c         8044 g        16006 t
ORIGIN      
        1 gagtgtaaca taaatggctt ttttatttgt ctcgcttaat tatacaaacg gcgtattcaa
       61 aagatttatt tacttttttg tatagatttc gattgttcca cctagtcaat acaaatgagg
      121 taatcaggaa actgaaaaaa atcaatacaa aaaagccgat taagaaatac agcattttct
      181 tttctgataa aaaagcgtac aaggaaaaat ccttggctct ttctggtctc gttaatggga
      241 aaaagaccca tataaaagga agaacaacga tcatccatcc taaaagagcc actaacgttt
      301 gccaaatctt taaccagtaa ttaccttttg aaaaatactt atctttcacc aaaattgatg
      361 caacttcttc tcttgttact tttttcatat cctcacctca cgtttttttg ttacgacgta
      421 ggagtttacc atacatttca tttcttttca cataaagtgt tcctaaattt ttcctaagaa
      481 aaagaacaaa acatttctca tcagcaaatg aaaaatattt tgttcttttt atcagttgtt
      541 ctttttattt tttatctctt aattatgttg ctctttccaa tacgacaatg cttttcattc
      601 ctctagatat cgccgtgtac atttgtctgc gtcttctttg ctcatctcca tcgttttcaa
      661 atggatataa gattacatga tcaaattcca gtccttttgc tagactcaaa ggaatgattt
      721 ggcagttttc taatccatat gaattttttt taatcgattc ttgtagcgtt tgggtttcct
      781 cttctgtttg ggtgataact gccgcttttt ctccttttag agaaaccaaa atctcagcta
      841 gtattttcaa caattcttca gaggatcgaa aagagcggta ttcgggttct tttccttgcg
      901 gtcggatcga tacgatgtcg atcttctctt gatccacagc ataggttttg aaaagctctg
      961 tgattgctcc gctagaacgg taactatttc taagatcata ccgatggatc ggcagatggt
     1021 agtcatcgaa acaacgcata atatcagcaa aagtagtgga agaattaaag attgcctgat
     1081 tctcgtcacc tactaaagta aagtgagttt ttggaaataa ttcgatcaat agacctaatt
     1141 gtgccagggt ataatcttgt acttcatcaa tcaatagata gcgaaatgct ggtacattta
     1201 ccttttcaac aagtaaatga cgaatagcta atataatgac tgcttcatca acagtacgtg
     1261 tgggttgcca agcataagct gagccatatc gtttttcata aattctttca aacaactgat
     1321 gctcatccac ccatgccatt tcttcgattt gtctggttat ttttcgatat tttttttgta
     1381 aaagtttcct tgcataagct acaatacttt gttccgaatc atcagaaatc aatttaccga
     1441 ataattccaa ctgcctatct tctgtcaacg agagtacctg attctgcaca gcaggacttt
     1501 ttgcttgttt caaaagatga ttcttccatt cgctcatcag tgcctttttc gttgcttgaa
     1561 gcctatcgat caatttagga tgagcaggaa ctttctcata tattttttcg atcgtttttt
     1621 tagaaaggac tgtttttcca tttttagtaa gtccacggat aaaattcgga tgatctaaaa
     1681 acaaaggatc tgattgtttt agattatcga taaacttttt gctacgcaaa cgttctgtct
     1741 gctccgatac attttctccc gtgatacgtt tgaaataagc ctcttcacct tctatttcct
     1801 ctgctgaaag ctgtgaaacc agctgtatga tggttagatt cagtggattt ctttcaccta
     1861 atgatggtag gacattcgaa atatagtcga taaaccgatg attaggtgat agaatcagca
     1921 agtcatcgga tgtcatcgta tctcgatata aatagagcag atacgcaata cgctgcatga
     1981 tagcagaggt tttaccactt cctgctacgc catttaccaa gatattttga cttttcacat
     2041 cccgaatgat tgtgttttgt tccgattgga tcgtagcagt gatagccttc atttcattgg
     2101 tctcatcttg gcctaagact tctaataata cgtcatcttg aatagctaca gacgtatcaa
     2161 aaaacttgac caaacgatct ctttccaaaa gaaattgtcg tctttcttta ataaccgtat
     2221 cgattttatt ttgacgaacc gtataagaag atggaccaat catgttattg taaaaaagtt
     2281 cggcaattgg tgaacgccaa tcataaacaa gattttcatc tgcatcatct gtgaaatttg
     2341 ctgtaccgat ataaaaggat tcttttggct cattatccag aaagtctaca acgacttttc
     2401 caaagtaggg acttttcaat aaacgttcga tctttgctag ctgattttct gcgtttttct
     2461 gtttgatatt catctgatcg atttctctat ttttcatttc aatcatcgaa aaagtatcca
     2521 ggttatctaa gtaactgtca aaattcaatc gaagctcgcc agccatttct ttcaacgact
     2581 ggtttccttc tatttttgcc gtatccatcg attcccgcag ttcgtttttt ttatcaatta
     2641 gcttttgata cacgttcttc agatatgctt cttctaactg tttttgtgtg ttgaccatac
     2701 acattctcct ctttttttaa agtggtggaa ccgattagtt tacctctttt aagagtcgaa
     2761 tgcaagcttt ttaacgagta tcatttgtta ggatatatca gttcttcagg tcggacagtt
     2821 tgatataaag aaaatgcacc atcaaggttt tttacgtggt agccagactg cttcaagatt
     2881 ctttccgcta gatagctacg taatccgcta tgacagctga cgatatattc ttgttggctg
     2941 tctaattcat ttaatcggtc ccgaagttca ttcaaaggga tatgtttggc ttccttgaat
     3001 ttgccctttt ccaattcttc tgctgttcgc acatctaata aaatttttcc ttttgctagt
     3061 tctgtcggca attcatgcca ttgtacggtt tcactaagcc cttctgcaat gttcattgct
     3121 gcatatccta gcatgtttac tggatctttg gctgagccaa atggcggtgc atacgtcaat
     3181 tctaattccg gtaaatcgaa gatcgtcaaa tgccctttga ttgctgttgc taaaatatcg
     3241 atccgtttat ccacaccttt tgccccaaca ccttgtgcac cataaatctc gccagtctct
     3301 ggatggaaga tcaacttcag taaaatatct gttgcttctg gataatagct tgcatgatct
     3361 tttcctgata catgaatgac ttcaaaagac agttcgtttt ctttggctgt tctttcactt
     3421 aaaccggtgg atgcggcagt cattccaaac gttcgtataa ttgctgttcc aataccgcct
     3481 tgatttcttc gagaaattcc ggaaatcgtg tccgcaactt gtctaccttg acgattggct
     3541 ggtgaagcaa gagaaataag tgcatctttt ccagtgattt gctgttttac aacgatagca
     3601 tcccccaccg cataaatatc aggaatattc gtttgataac gttcgtctac taggataccc
     3661 ccgcgtatgc ctaattcgat tccagcggtc actgctagct ggttatcagg acgaacacca
     3721 atggataaaa taactaaatc agcagggatg gtacgcccat catccagtcg caatcgtttc
     3781 ccgtggtctt caaatccagc gacagcatga gaagtaatca cttctactcc ttgatgagac
     3841 aattcttttt ctataaaagc tgccatttct tcatccagtg ttggaagaat atgtggtgct
     3901 tgttcgatca ccatgacttc taaacctctt ctttttaggt tttctgccat ttccaatccg
     3961 atgaatcctg caccaacgat cacggcacgc tttggctgtt tttctaatgc atgcatcact
     4021 ttatcgatat ctggtacatt tctaatagaa aaaacattgt cggcttctgt tatccctgga
     4081 atcgatggaa caactggttt tgcaccagga gataaaacca atgcatcgta ctgttcaatg
     4141 tgtttttgac cctcatgtac gacttctacc gttttgtttt cgggaaagat ggctgtcact
     4201 tcatgatttg gacgcacatc taaacaaaaa cgagcggata atgattctgg cgtttggaca
     4261 agaagatttt cccgttcact gatttctccc gaaagataat aaggcaagcc gcaatttgca
     4321 aaagaaacat acggtccttt ttcaaaaaca acgatttctg catcttccat taatcggcga
     4381 agccgtgtag cagcagacat tccacctgct acacctccga caataacgat tttcatctta
     4441 tttccctcct actgttcgat caaaccattg attcatgcca ccacgtacat tcactacatc
     4501 ataaccagat ttctttaatt ctttagctgc ttgtttactc ctcatccctg attgacaaat
     4561 cacatagacg gtcttttctt tgtctccatc atatctgttt atactttgta atggaacatt
     4621 tttagctcct tttatatgcc cgccccggta ttctgcaggt gttctaacat caagtaacgc
     4681 tggattttcc aaaagctttt cctttaattc tgggactgtt atcgatttta ttgattgaaa
     4741 tagcaaattc attttctgca cctcatttac atttttataa atacctcatg gggtatatta
     4801 aacaggagct ttattaatat gtcaaccaga atgactcttc atttttttca ctacttttta
     4861 tatttgcata aaataccgat aaggggtatt atctaattat aaaaatagag gagaatgtgt
     4921 tatggagatt gataataaaa atatcctgaa ccgtttgaaa cgtacagagg gacaaattcg
     4981 tggtatccaa aaaatgatcg aagacgaaaa agaatgtatg gatgtcatca ctcaattaag
     5041 cgctgttcgt tctagtattg atcgcgtaat gggcatgatc gttgcagata atctgaaaaa
     5101 ttgctttgag aaacctgata gtaatccaga agaacaagcg gctaaactag aacaagcgat
     5161 caagatgatt attaaaaagt aaaggaatga tttcaatgaa agtcgttttc catattgatg
     5221 aattagaaaa atggtcagaa acagggaaaa acgtaaaaaa cctgataaaa gcttctccag
     5281 aaacgacgat tgtcgtatct gtaaatggca tcgcgattac cggttatcta gactctgcca
     5341 atgcagaatt cttagatttg caaggagtcg tttttcacgc ttgcgccaat gctatgcgtg
     5401 ctaatcatat ttcagaaagt tctttacctg aacaagtaat cgttgtacca gcaggtgtcc
     5461 ttgatttagt tgaactgcaa tcccaaggtt atgcttatat caagccttag tcagtagagg
     5521 ttgcgacaga agtgatcagc ttcaagaaat ttcggcttat ttttcgaaga agctacttct
     5581 ggaaaaccgt gaatcaaagg ttgtgaaaac gctgtcctgc atcaagtaat aagaacagcc
     5641 aaacaaaaat agcttctcat atttttcgtt tggttgggct tattaccgca gatgcaagct
     5701 tttgaacacc gtttaaggaa gaggttgtga aatcagcggt ttgacctaag tattagagaa
     5761 aaaaacggga aaatagctcc tcatattttg ccgttttttg agctaatacc gaaggtcagc
     5821 tgattgaaca ccgtttacca agaggttgtg agcctaccat ttaactccga atcacaagaa
     5881 ataatttcaa aaacaacttc tcctgttttt ggtttggttg gcttattatc gagaagtagc
     5941 tactgggagt ctatttatca aaaaaaggaa tgcgacatag gtcacacccc ttttttattt
     6001 tctttgaaac atctttcggt actcgacagc atacaagaca aaagattgta aaagaccgta
     6061 agtgatgacg gcaaaaatga ctctcaccca cagcgttggt aattctggga aaagcagcaa
     6121 aaggatcatg ccaacataga tgacagcagt cgctactttg ccataccact tcgctccact
     6181 taatttgata tttttagata gcccgattaa tccagctaca aacataaagc cttcttttat
     6241 caagaataga ccaaacaaca gccaaagcca cggtcgatac catgccatag acaaaatcag
     6301 aaaaagttgt gtcaatttat ctgcaaacgg atcaagcacc ttccctaagt ctgttacctg
     6361 attatatctc cgagcaatga ccccgtctag ataatcagac aaacctgaga caacaatgac
     6421 cgctcctgct atataaaatg actgtctcag cacaaaataa agataaatcg gcagcaaaaa
     6481 aatacggaat atcgataaaa gattcggaat cgtttgtatt tctttacgcc agtctgtgct
     6541 taatttcatt ttatcgccct acctcctcag cactcttttc tttttatttt agcttacacg
     6601 gggaataaaa ccaatgattt cactgttttt atttttcttt acagccactg atattatgag
     6661 ctaatttgag ataatcactt gctgttttca tcgtttactc ttctttcttc ctgtcgtttg
     6721 cgcatttctt ttactagtac tttatgagct ttttttgatc ctcgctctag gtcacgctgc
     6781 cgtttacgtg ttttataatc gataaacaga ctgtctaaat cgtaacctgt cgggtacaga
     6841 tcttctgctg aacgcaccag acgaacacgc tgacgaggca cgtggattat ttttttgtct
     6901 aaatatacat caatcgtatc ttcacctata tcttcataaa ctaacgcttc tttttggtat
     6961 tcattgacaa atatccgatc accttttgca aagagctggc gttctttttt attctccttc
     7021 ctatttgtaa ctgctgtctt aggaagaaat tcttttttct gtgtccgata ggctttttcc
     7081 gccaagtaac gctctgcttg atggatcaat ttcatcgaca tatccatttt atgagcaatc
     7141 cacaaagctt ggctttctcc tgtttctcca acccgcaact gatatttagg acgaagtgct
     7201 tcccgatcga aagccatagc agccggcaca aaatcttcat gatctccggc gaatttcttg
     7261 atttctccat aatgggtcgt ggcaatgatc aatgcccctt gctcatacat agattccatg
     7321 attgcgatcg ctagtgcagc cccttcattt ggctctgttc cactgccaat ctcatctaaa
     7381 agtaccaacg tattcctttt tatctttttc aaaatagcag cgatgttttg catatgacca
     7441 gaaaatgtac tcaacgcatt ttctaaattt tggtggtcac cgacatcgac gaaaatctca
     7501 tcaaagacag caagctctgt cccttctttt gccggaactt gcataccgaa catcgccatc
     7561 aaagtcaata aaccgactgt cttcaacacg actgttttgc ctccggcatt tgctccggtg
     7621 ataatcaagc ctcgatagtc tttaccgatt tcaacatcca atggtaccgc atgctcaggt
     7681 aaaaatggat gtctgccttg cttgataatg atatgttccg atttattgat tctaggtgtg
     7741 cttccattga tttctcggct aaattttgcc cgagcaaaga tgatatctaa caccgtgatc
     7801 gtttcgatca ataaatcgat cacttcttcg ttttctgcga tagcaccagt caatgccgcc
     7861 aggacttgat attcttcact gatttcttca gcttttaaca actgatagtg ttcattcaat
     7921 ttagaaatca cagttggttc aataaaaacc gtcgttcttt tatttgattc atcgataatc
     7981 gttccatcta ttttattttt atagctggct ttgataggaa tcgtatagta ttcgcctttt
     8041 tgaacaatca ttgcttcttg gatcatttct ttgtttttcg gatgacgcaa gaatttcagt
     8101 aattttgact ggatttcttt ttcgattagt tgtaattgtt tgcgtacttt acgcaaatta
     8161 cgtgacgcgt cgtcactgac tttattattt tttattttct ggtcaatcaa ctcttctaca
     8221 tttatcaaat caggaagatg tttgctataa gcaaacaaca agggtgtctg gtattgattc
     8281 ttatcaaaaa actttgtgat catccgactg cttctaagaa aatccgcata ttcgatcaaa
     8341 tcggttggct gcagaatcaa cccttttttg acttgttctg tcagtgcatc gatcctcggc
     8401 aaccccataa atggaacatg ctgactgctt tctaagatca agcgtgcttc tcttgtttct
     8461 tcttgacgat ccaagacagt ttgtaggttt gtcgagaccg tcatatcgct gattcgtttt
     8521 ttgctatagt ttccaattgc tcttgcttgg atttcctttt tgatccgatc aaattgtaat
     8581 tgactaatca tttcgttgtc catattctct ccttttcttg aagagatacc tgtcccaaaa
     8641 taaataaggg cctagagata aataaaagga tagaacacag cttaaaaaag tcatgtccta
     8701 tccttattag aatacaaaga tattgttttc ctgacaggta ccgtttcata agcacaccaa
     8761 ataaactttg tttattggct attcgactta ctgattagat accagctaca ctcacaaaac
     8821 ataccccatt cttctaggtc ttatttattt tccacttaac tatagcaaga cacattttgg
     8881 ttgtcaaact ttagtatgtt ttatagattt acaccattaa tgaatagaca cctaccgcga
     8941 taattgctcc gatcattgga cctgcgattg gtacccatga atatgcccaa tctgaagttc
     9001 ctttattagc tattggcaat accgcatgtg ctaatcgagg accaaagtcc cgagcagggt
     9061 tgattgcata tcctgttggc cctcctaatg aaagaccgat ggctaagatc aatccaccta
     9121 cagcgaatac gttcgttcca ggtgcaaatt cgttttgtcc aaaagctagc aacccaagaa
     9181 ctaatacaaa tgtaccaatt aattctgtga tcacatttgc tggataattc cgtatagcag
     9241 gacctgttgc aaacgttcct aaaatcgcgc tttcatcttt cgttgcattc caatgtggca
     9301 aataagaaag ccaaacaaga atggcccctg caaaagctcc taaaacttgc gcaatgatga
     9361 aaggaacgac aagattccaa ctaattgccc ctgtcatcgc catagctaga gagactgcag
     9421 gattcaaatg agctgggccc atgaatccag aaatatagac agccattgtt acagcgagtc
     9481 cccaaccaaa tgcgatgaca atccagccag aagcctgtgc tttacttttg tttaaattca
     9541 cagccgcaca cacaccatct ccaagcaaaa ctaggatcag tgtcccaata aactccccca
     9601 tgatttgagt catatcactg ttcatttatt tctccccctt tagttcccgc agatctgatt
     9661 ctgcaatcaa tgcttctaaa cgtttagtct gttgcgcctt ctcctcttct gtccattcaa
     9721 aatatccagc aattgcatcg atcacaggtt gcttgatctc atcaagctga tctcgttcaa
     9781 acaacagatg atttgtacga cgaatgagat aatcgcctgg ggccaaaacc atttcttctt
     9841 ctaaaccata acgtaaccga gctgactcag cgagactcaa accaggataa ggtgccattt
     9901 cttttgctaa ttcaaagata cgtcgggcat tagtcccgta aaaatcagcg atataagtag
     9961 catcttcttc ctctaaaccg gctgctactc cttcttttgc taattctgtc actgtttctt
    10021 ctaatttagt tggatcgaag tttccacctg aaatctgata ttttttagag tcgatttctt
    10081 tcgtctctat tccgtattct tcttttaata attggcgtat caatcgcaaa gctccttctg
    10141 ccatcttacg gtaatcggtg attttcccac cagataaagt cagcaaacca tctggttctc
    10201 tttctaaaga actacctctg gaaatcgtag aaggtgcttt ttcatcacgg ctgttttcca
    10261 aatggttcaa cacgtcttct acttcagcac gagaaacttt gttttcctta tattcactta
    10321 ctgtatcgac aactttattg aagctcttgt ctgaaatcga tccattatct ccaccattgt
    10381 aatcagaacc agaattacca atcaacagtg gacgaagtcc tgcccagctt gcttcgatat
    10441 cattcaatgt gatatttgct tctggatagc gatgattgat cacatccaat agataatcta
    10501 catcttcttg tgtgactttc ggatccgtaa aatctccttg gtaatccgta tctgtcgtac
    10561 caaagtaagt cttgttttct cttggaatag caaaaaccat ccgcccatct tgctttcctg
    10621 tatcgaagta tgtgggttgc ggtacaggca gttttttcgc atctacaact aaatggatcc
    10681 ctttagttgg acgcatttta ggagagactg gacgcgtaaa attcaagttt cgtactttat
    10741 ctacccaagg accactcgta ttgatcacta attttgcttt gatttcgatc acttcatctg
    10801 tcagcaggtc acgagctttg acgccaacga tttgatcgcc atcatataaa aagccaaccg
    10861 ctttcatttt acttactaga taagccccat cttcggcagc ctttttgata ttatcaatca
    10921 ctaaacgggc atcattgttg cggaaatcta gatagacacc cgcgcctttt agcccttctt
    10981 ttttcaaaaa cggttctctt tccaatactt cttctggtgt cagcgtataa ttctcatatt
    11041 tggttcctgt cacatttgcc agtttgtcat aaaggtccat tgctactttg accgagaaca
    11101 tattgaaggt tgttgctcct tcgccctcat agattggcaa aagcattgga tctggttttg
    11161 ggatgtgtgg ggcaatactt tgtacgactg cacgttcacc aactgtgtca gctactactt
    11221 ccacatcaaa tgtcttcaga taacgaatac cgccatgaac aagtttggtc gagcgagagg
    11281 aagtcccttc tgcaaaatcc tgcatttcga tcaatcctgt tttgattcct gatgctgctg
    11341 actggactgc cacaccggca ccagtgattc cgccaccgat gatcaacaga tccaattctt
    11401 cttgctgcat tttttgaatg ctatcttgtc ttgtcttgtt tgaaaacata tggatttcct
    11461 ccttattcaa atgcttgggt agcttttact gcttttttcc aaccgttgta aagtttttct
    11521 cggcgctctt cctccatttg aacttcaaat agcttgccag cttcataaaa ttcgcggatc
    11581 tcgtctgtat ctttccaata accgacagct aatcctgcta aaaatgctgc ccctagcgcc
    11641 gttgtttcca agttttctgc tcgttggatc ggtacattca agatatctgt ttggaattgc
    11701 atcagatatt cattgtttgc tgcaccgcca tctactttca atacaggaat cttgattcca
    11761 gtgtcatctt gcatcgtatc gatgatatct ctcacttgat aagcaatcga ctgtaaagta
    11821 gctttaatga tatcttcttt tgtcgtacca cgtgtcaagc caaacatagc ccctcgtgct
    11881 gcctgatccc aataaggagc acctagccca acgaatgcag gaacaacata aacctcatct
    11941 tcgcttgtag agcgtttcgc tgcgtcttct gaatcgctag ctttttgcaa catttgaagt
    12001 ccatctctca gccattgaat cgaagaacca gccacaaaaa tacttccttc taaagcatag
    12061 taaacctttc catttatgcc gtaaccaatt gtcgtcaata aattattttt ggataattgc
    12121 ggtttttcac cggtattcat gacaataaat gaacctgtac cataagtatt cttgaccatg
    12181 cctggttcga atgccatttg tccgaataat gcggcttgct ggtctcctgc catccctgaa
    12241 attggtgctt cgcttccata aaaatgataa ccttgcgtat aaccataaac ttctgagtta
    12301 gaagtgactt ttggtaacat cactcgagga atatttagta aatctaaaat ctcctgatcc
    12361 caatctagct gatggatatt gaacaacatc gtccgactgg cattcgagta atcagtaaca
    12421 tgtgcttgtc catcggtcag tttccatact aaccaagaat cgatcgttcc aaacatcaat
    12481 tcgccttttt cagctcgttc ttgcgcgcct tctacatgat caagaatcca gcgtatcttc
    12541 gttgctgaga aataggcatc gatcactaac cctgtttttt cgtggaaaaa ttcttgatag
    12601 ccttcatttt ttaagttatc tgcaattcca gctgactgtc tggattgcca aacaactgca
    12661 tgatagattg gacgtcctgt atctttttcc catattactg ttgtttcacg ctggttcgtt
    12721 atgccaatcc cagcaatctg atttggtttg atccctgatt cgatgaacgc tccggcaata
    12781 actgactgta cagaattcca gatttcattt gcatcatgtt ccacccaact ttcttgcggg
    12841 aaatattgcg tgaactcttt ttgagaactg ccgatgtgtc ttcctttctt gtcaaagata
    12901 attgctcgtg agctagttgt accttggtca atcgccatga tatacgttga ttctgtcatt
    12961 gtgattccct ccattatatg caaacgcttt ctttaactac tcttatcata ctactgtttt
    13021 aaaaaaagaa actgtcaaaa ttttattctt tttttctttt tttgacagtt ttttattatg
    13081 aagctatttt ttaatcaatt cttttctttt ttcagcgtct ctattcttct tttcaatcga
    13141 ataatgtcgt aaggtgacgc aaattctgac agataatatt cacactgttt tttgtttctc
    13201 tggcaaaatg tgatcaccaa atcatattct ttaccttctt cataacttcc aatctcaata
    13261 ccgccgattc ccctcagttc tctgatcaga tattgttgaa aagcaatacg ataaatcggc
    13321 agactttcta aatcgattcc aatcactact ggttttgcaa tataaaaatc gatcatcaaa
    13381 agaacattgg catactggat catcaggtaa ctaagctcac tatcttcagc tcttttcctc
    13441 ggcaattgct gcaccgctgt ttcctgtaat ttcgccagta actgtgttaa ggaatgcccg
    13501 agcattttct gctgctgttc caaaagccga tcacgctcat agacttcgat ctttccaaca
    13561 aagaaaaacc attcattgtt gatctgggaa atttggtagc ctactgcctt ttcttctttg
    13621 attttcaaac gacgaggacg ataatgccat aacatcgttt cccgaatgta agtatctaaa
    13681 acagcggttg gtaacttttt gctccgtgtc aaatcatact gataaaatat ttcttcgtct
    13741 actatcgaaa aagaaacaaa aaagctgtaa aacatcattg tttcgtatac attcagttct
    13801 gctgctgttc gactaagatg catcacgatg attggatcga ttgcttgata aagccggtcc
    13861 gactgataga gtaatttctt ttctttcaaa gttgcgtacg tacttttttc attcaatagt
    13921 ctttttttcg taatcccgag ccagcaagca atctgtgctt ctgctgatgc cgtaaacgtt
    13981 gtttctaata cacggtccaa tcctagaatg aacggtcttt tttctggtgt attttgcaaa
    14041 aaaagcggtc gctgatcttc cgggatatat tggaatagtt cataataaaa atatcgtatc
    14101 tgtagctctt ctccgtataa ttgaccgttt ttgatttgta atccaaattc ctctaagagc
    14161 tggttcaatt ctttgatctt tcgaaaaaca gaagactcac tgatattaaa cgctgtcgct
    14221 aatcgaacga tggatacttg ctgatgttct aataaataga cgagcatctt aaacttcaag
    14281 ctttcctgca ataaaaacaa tagaattttt tccaaactta catcttcgtc caacacaagc
    14341 agcgcctgat actcatttcg ctgtacttct actttttttt ccatcattcg gccaatcaat
    14401 tcaatatctt ccaaatattg atcaaacgag gcttttgaca gttggacatg ctctctcaaa
    14461 ccattgatag aggctgttcc cccttgcaga acaaggtttc gcaaaatcag gatctgtaac
    14521 tgctcttttc tttctaataa tgcttcaatc ttcataggca gtattcgcca cctttgacca
    14581 caccatatct ggcacacggt attctggctg gaaaaatagc tcatgttctt ctaactgttc
    14641 aaacgtccat ccttctttta ctgcaattgt cagttggtca agaaggtgga acatctcttt
    14701 tttgctttgg agctgtgctc caagaatctt tttttcagaa tcaaatagaa atttgagttt
    14761 aactttgctt tgatttattg ctgtaagctt gtagtctacg tatcctgttt caattttttg
    14821 gggataaaaa atgctctctt cttctgtcaa acctacgctt cctaagaaat agccaaacca
    14881 ctgattgccg actggacgat aggttccctg atcctttgtc tgtgagccac taattgtctt
    14941 gctgacattt cgtgctgtac ggacagcgtt atttactaga gaaacataca ttttttcatt
    15001 tgttggacga aaagttactt ggatcgcatc gccaatcgca taaacgtctt tttgagacgt
    15061 ttgcaagtag tcatctaccc agatcgttcc atcatcattc aatgttaatt gttcttccca
    15121 catctgattg tcggggcgag aatgattagc cagcaaaaca agatcatagt tctcctttct
    15181 tttttccgtc tctacaatag cggtttcatt ttcggtcaaa gacacaactt gttcttctaa
    15241 aaaaagtgaa agcccttgat ttttcatttc ctttactaac ggttctgtca tttcaggatc
    15301 tagataacga aaaagaattg actttcggct ttcgtaaaga tggatttgtt tttttcttga
    15361 tgccaaccct tcagctattt cgattcctgc ttgtcctgca ccaataattg caattttctt
    15421 tgcattcatg atcttttgct gaagagccgt tacgttttgt atctttttaa ctgggtgaat
    15481 aagcgttgat tctgcagaaa tatttcgaaa cttttgattt gaaccagtcg ctagaatcaa
    15541 acgatcaaaa tccaattttt ttcctcctgc taaaacgact tttttttctt tcaatcctat
    15601 tactgtcttt tctgtgtaaa catggattcg atagcggtca gtcagttctt ctttcgtgat
    15661 ccaagaaagt tgtttttcac tggtaacctt tccttttaat atcaaattga acccgctggg
    15721 aatccatcct aacttcgatt gcttttcaat caaatatatt tcacttgttg gcatcaattg
    15781 gcgaagataa atagccgcat gaatccctgc aaacgacccg ccgacaatta caatgttcat
    15841 ctgcattcct ctttcttata aggtgttcta ctgctaactt ctcaatcaga aaacacagta
    15901 ttcataactc gctttcaacc ttatgataca tagcgatgca gcagaatcaa ccctctccat
    15961 cataccgtgt tctaggtctg cttctcaata atgtactagt ggacctaatt gaagagtatc
    16021 atttctgaag agatgtttca aaaaatgtac tcttataaaa gaaaaaaact cgccttttac
    16081 gtacctctgt ccaaatagga aacagaaaag aacgaaaaga cgagttttag cgtgtgtaat
    16141 gtaatagtta gaatagacac atcatttatt tttaattctt taatgcttca acaactgctt
    16201 cgcctaattg atgagcagat tgaggatttt gccctgtaag aagccgccca tcaatttgaa
    16261 ccacttctga aaaagctgct ccagactgat agtttgctcc tttttctttc aaagcatctt
    16321 ctgctaagaa tggtacttca ttcgttgtac catttgcttc ctcttcttca ttactgaacc
    16381 cagtcactgt acgtccagct aaaatagatt ttccagactc atctgtaact ggcaacaatc
    16441 ctacaacacc gtgacaaaca gctgagacca gcccttcatt tcgatagatt tgtgaagcga
    16501 ctttcccaag atctattgct tctggaaaat cccacattgt tccgtggcca ccagcataat
    16561 aaaccgctgc ataatcattt gcatccacat catcaggacg taaggtattt cccaaggccc
    16621 gatttctgaa atcttcatct tcataatagg cccaatcgat ttcatccata ttcaaaacac
    16681 tttgcggttc taaaggtaca tatccgcctt taggactgac aaaatctgca tcgatcccat
    16741 tttttactaa tacatcataa aaatgagtca gttcacttaa ccacaaacct gtaggacgct
    16801 cgatcttttc gtacttttct acatttgtta atacgatcaa tactttcatt ttcccatcct
    16861 ctttctataa aaattgcgtt attgataacg tgctttcaag aaattatata atgggcttgg
    16921 caaataaagc tctttatatg cttcttcaaa aggtttcgtt acaaattcat cctcacggtt
    16981 ttccaataat ttctctgccc agtcaggatc gacgatcatt tgctgtccaa ttgctgcaag
    17041 ttctgcatat ttcaatacct gctctacatc ttcgcgattg cggatcccac cgacaccaac
    17101 taaagggatc tttccttgaa tcgtgttatg gaccacttca agaatcgatt tatcgttgta
    17161 tttatcagaa cgagctattc gatcatacat atttaatgaa acatgcagat aatctagttt
    17221 tgactcacgt aatcgttcaa gaagccagat cgtgtcttca aaacggatac ctggtgtttc
    17281 atattcttct ggtgagaaac gataccctac gatgaatggt tttttagcat attgttcaac
    17341 cgctgagaaa accgttgtta ataattcttc aataaaacga taacgatttt ccaagctacc
    17401 gccccattga tcctctcgtc tattcgaatg cggagagaaa aattgttgga tcaaatacgt
    17461 atttgctcca tgcaactcga ttccatcaaa tcctgattca atcgctctac gtgtggcttt
    17521 gccaaatgct tggattgttt caacgatttc ttcttcactc attgctcgtg gtgtttccgc
    17581 atcaggacgt tttgctgcaa ctgcacttgc agatacaggc tgttctccag ataaagttgc
    17641 tcgacttgtc attcgtccac cgtggaaaat ctgaataatc gcttttgcgc cttctccttg
    17701 gattgctttc gctagctcac ttaatcgagg aatcatttca tcatgagcga tgctgagttc
    17761 acctggccag ccttttccga tatcttggac atttgcagca ccagtaataa cagcaccaag
    17821 acctttagaa cgttgtttat aataagtgat ctcatcttcg gtgatcactc cattgaaaaa
    17881 gctgagttgt gtcgtcatag gcgacagcat caatcggttc ttcaattgaa ctcctgaagg
    17941 taaagtaatt gattgatcaa attgtgacat tgtcattcct cccataattc gctctgatta
    18001 acctatcgag aatcatctat cattaaacca ctcgattagt tgtacatgca actaatttgc
    18061 ttaaaaaatt ttattttttt tgtaacttat ctgttgcatc attcattgtc tgggctaatt
    18121 ctttacttgc ttcatttccc aaaactgctt tgtatgactg atgaagttct tcccagctac
    18181 catcgacttc cttagcaaat tggcgtcctt gttctgtaag ataaactaat gacaagcgac
    18241 cttcgctaac tgttttgacg tatcctttat attctaattt ttcaacaaaa cgagcaatcg
    18301 ttgatggggc ggaatagagc atttgtgcaa tatctttttg tggtattcca tctttttctt
    18361 ttaatatcaa taaaataaaa ccataagttg gtgccagacc tgtccttcta aacgcttcat
    18421 cagctaattt attcaacatg cgatctagct ttttcacgct aaagaaaaga cattcatcta
    18481 acgctttttc aattggcttt tccatttcat cccctccatt ggcgtacata tcatagtatg
    18541 atttttattt tttgtcaaaa aacacggaat aatgtccgcc tcctctgtct agatttgaaa
    18601 aaaagaagta gccatcttca aagaatttcg gcttgttttc gacaaaactc cttctggaac
    18661 accgtgaatc agaggttgtg aaaaagtcgt ttagttttga gtatgaagaa aaattttgtg
    18721 aaaatggctt tccacatttt tgcataaatt tggcttaata ccgaaaaact ggcttttgaa
    18781 caccgtttat atcagaggtt gtgaaaaagc cgtcctgcat caagtaataa gaacagccaa
    18841 acaaaaatag ttcctcatat tttgtcgttt tttgagctaa tgccgatggt cagctgattg
    18901 tacaccgttt attgagaggt cgtgagcctg ccgttgaact ccgagtcaca aggagcaatt
    18961 tcaaaaaaca gcttctcatg ttttatgact atggtgactt gtgatcgagg agttggcagg
    19021 agaatactgt ttattcgtaa agaaggggct gtgacaagac ttttgtcaca gtcccttatt
    19081 tccttttatt ataggatttc gccatttgat tggatgactt gtctgtacca atcaaatgat
    19141 tttttcttta accgtttctt tgtgccattc ccttcgtcat cttgatcaac atagatatat
    19201 ccataacgtt ttgacatttg tgaagtagaa gcgctgacga tatcaatgca gccccacgac
    19261 gtataaccaa ataaatctac tccatcttcg atagcttcct tcatctgctc aatatgctgc
    19321 ttcaaatagt caatgcggta atcgtcttga acggttccat cttcttctac tttgtctata
    19381 gctccgagtc cgttttcagc tatgaacagt ggtttttgat acctatcata taattgattc
    19441 aaagcaattc tcaaaccctt aggatcaatc tgccagcccc attcacttga tggaagatac
    19501 ggatttttaa ttcctccagt tattaagttt ccttggaccc cttccaaatt ttctggatga
    19561 gcactgactg cactagacat gtagtagcta aaagaaacaa aatcaacagg gtaggctgct
    19621 aagatttctt catcacctac ttctattttt aagttgacac ctttttcttc aaacattcgt
    19681 tgcgtatacg ctggataata tcctcttgct tgaacatcac taaagaacaa agaagttctt
    19741 tgctgctcaa ttgttttttg aatatcatcc ggatcacaag aatacggaac aagaagctga
    19801 tagctgatca tacaaccgac ttgtgaacct ttgataattt catgacaagc ttttgtagct
    19861 aaagcacttg ctataaactg atggtgtgca ccttggtatt tcgcttgttc caaatgggga
    19921 tggttttctt caattactcc tacgctaaca aaagggtgat gttttacaca gttgatctca
    19981 ttgaaagtca tccaatattt tactttattt ttatagcgtt tgaatactgt ttcagcgaaa
    20041 cgaacgtaaa actgaataag ctttcgatta ggccatccac catattctgt aaccaaatat
    20101 aacggcattt cataatggga aagagaaacg actggctcaa tcccatattt tagacattcg
    20161 tcaaacactt gatcataaaa aaataatccc gcttcattgg gtgtttcttc atcaccatga
    20221 ggaaaaattc ttgtccatgc gatagacatc cgatagcatt taaaacccat ttcagcaaat
    20281 aaacggatgt cttctttaaa gtgatgatag aaatcatttc cgtgtctttt aggataataa
    20341 tacttgctgt tgggatcctg cgccgctttt acttgctgat gcgtcatcat atgccattga
    20401 tctgtccatt tttctttagg taaatcgctg tcgaatgtat acacatcaga cacagataat
    20461 cctttttcat ctacatccca tgcaccttca cattgattgg ccgctgtcgc tccgccccat
    20521 aaaaatcctt ctggaaattt tttcatatcg atccccctaa acttgctagt tttcttgttt
    20581 gattattttt cttatgacta gtaatgatat ttttgaatct actactattt gtaacaataa
    20641 ccattgtggt cggatcatat ccctctttga ttaattcttg caaatctact tccatcaata
    20701 aatcgccttt acgtactttt tttccatcag atactgcact ttgaaagtat ttgccattta
    20761 aattcactgt atcaataccg atatggatca gtatctctgc tccttcttca ctgactaccc
    20821 caattgcatg tttcgttgga aaaactgttg aaacttcccc gtttacagga ctgtagattt
    20881 ttccgtccgt tggaatgatc gcaaaccctt ctcctaaaga tccactagca aatgttggat
    20941 cgtttacttc agataaatca attatttcac ctgctgcagg agtacttaac actatatcct
    21001 ttgaggattc ttcttcgatt tcatccttgt agccgaaaag aaaagttagc atacaggaac
    21061 tgatcatcgc taagaaataa ctagcaacta gccaaacaaa tccttcacca atataaatcg
    21121 ggaaagacaa aatacttctt gtagcaactg ccaaagcacc ggctcctgcg gcaccagcta
    21181 ctccaccaaa tatagctcca catatacaag caatgtaaaa tggtcgttta tatttaagag
    21241 tcacaccata aacagcaggt tcagtgattc caaataatgc tgtgataaat gcagataaag
    21301 ataaactttt tactttctta tttttcgttt tcaaaaatac cccaagtact gctcctgctt
    21361 gcgcagctac ggcagtcata catgctggac ctagcgtatc acgaccgtag aaagaaagat
    21421 tgttggtcat tactggtaca agtccccaat gtaacccaaa aatcactaac acttgccaaa
    21481 atccgccgat aacagcacca gataaaacag ggctaaagtt ataaacagct aaatatccag
    21541 ctgcaatcag ctgacttgca taatctgcaa ttggacctac aactaataaa gtaattggga
    21601 ccatcacgat gatacaaatg aatggtgtca ataaatttcg aatactttcg tgcaagcttt
    21661 tgcgaatctt aggctcaata taagaaagaa cccatacagc taaaattgct ggaataaccg
    21721 tacttgtata tcttgctaga atcacgggca tccctagaaa tcgcaaggtt atgctatcac
    21781 tatatgcact gacaatcgta ggataaacga gagctgctgc aataaccata gcgatgaaac
    21841 gatctgtatt gaactttttt gcagcagtat atgccaaaaa tataggcaag aaatagaaaa
    21901 atgcatcagc tgctgcattc aaaatgatat aagttcctga ttcagtagtt aataaattca
    21961 aactcgtaca taaggcgagt actcctttga tcaaaccact tcctgccaag acgcctaaag
    22021 tcggggcaaa aacagcggcg atcatgtcta taaaagagtt taaaatgcct tttttctcag
    22081 ttcctctctt tccactagat gcatcatctt ctagtttcat ttgtttggat aatacgtcat
    22141 acacttcatt tactgcattt cctactacga cttgaaacat tcctccagct tcgactacag
    22201 tgatcacacc ttctagttgc tctaccttct ccttatctgc cttcttatta tcttttaggg
    22261 taaagcgtaa ccttgttgca caatggtaaa cattgctgac attttcttcg cctccgacaa
    22321 atcggacaat atctttcgct aattgtgaat agtccatttt tacttccccc ttgttaatta
    22381 atgccgtagc aatccttctt acaagataag tatagttctt agaaaacggt ttctccattc
    22441 aattagtacc ccttctaata gcgaacgaaa ctgtacaata gtgtgtatgg tttacttagc
    22501 cgagcaaatc actcactgct tgaaagaaaa caagtatatc gtttctctta tagtcaaagg
    22561 agacaaaaaa aacacgcttg atcttccttt gctgatgtat aagtggtatc tcaagctgat
    22621 actctgtgat ttttgtttct acttggcttt tgataagaca gcacaacaaa gtctcggcat
    22681 ttaacggaag cataactagg tcagaactag gagagattag ttgctgaatg gaatctatct
    22741 ttttatggat ttttatttga ttttcttctt tgtagtaatg atcaagcagt tttgttttct
    22801 ttttttcttc aactatggtc agcttttcac gcaaaatctg ataaatctcc gaagattcaa
    22861 actcatctag aacactaggt agataaatca aatcatccca ctcaaaaata agctcttgct
    22921 cagtagtcaa aattgcatca tattccgtta ttttgtttga ttgatttttg aaaagataca
    22981 ctggttctat ccggcattct ttgatccaca tgttcatact ttgttgaatc tgttttttta
    23041 gtgtattcaa aatactaatt ggctggttac taacaatcag tatctcccct tgttttcgaa
    23101 aaggattcaa cgcttcggca agatacaaaa ccaaataagc gctttcagct aaattgggac
    23161 gtaattgaaa atgtattggg aagaaacgcc gaattaaata aatttctaaa ggataacggg
    23221 agatgatctt ttgtacaaaa tgattcatgg tattatgtcc ggcatccatc ctcgttttca
    23281 tttgtttgat atgggttagc aaaaattctg tttcatggaa caataacgaa acaggaagat
    23341 ctaaaaaacg aataatcgtt tgctcaaatg ctcttagatt cttctctatt tctttgtttt
    23401 tttcatcatt aatcatcaaa taatttaact ctaatagtcg attttcaatt gcttgttttt
    23461 cttgattgga aaaagaatag ggtagttctg atgataactt ttttgtgagg gtctctacca
    23521 tcggaataaa taatgtatac ctgtttgttt tttctaaaag ttcttctctt cgaagaatgg
    23581 tcaaaacgag ataccgagaa aatcgtatga agtcctctcc tgaaacaata taattatatg
    23641 atataagaac ctcttttaat gtcttttgga cagtcggcat gatattggaa aaaattgtac
    23701 tgatttgttg aggcaacctt gcgtgttgga tcaccgtttc tgttccaaca agagataaga
    23761 aaattctttt tgaattttct tcagcaatga tttttagtcc ttttgtcgac gaaacttcca
    23821 gttctaattt aggattgcgc tcgatccaac gcaaaatcgt ttttatttgt aatgatacgg
    23881 ctgtttttga aagaaagaaa atgtctgcta tcttttgcat actgacatac cctttttgaa
    23941 acaataagta cgtcacaata gttgaagctc ggaaatccat gctggaatag attttatgtt
    24001 tcgtcacctc ttgtatgatt tgctgtttag tttcagattc aattgattct aaaaaataac
    24061 ctgaacgttt atttgactgg ataatgattt tcttctcgta gatagcaagc atatttttga
    24121 tttcagtttg gatcgttttc ttgttggtac ctaaagcttc agctaattct tcgcttgtta
    24181 tccaatgatt cttatttctt aatactacaa gaatttggag ttgtcgttta tttaagtcca
    24241 tttgcttaca cctcctcttt gttataaaca tacaggaaaa acctctcaaa tgacaatagt
    24301 cacttgcaga ggtttaaaaa tcatttgaag aaagatctat attcaaggtt tttaccatta
    24361 gactggataa tttgtttata atattcaaaa ctatcttttt tcaatctcct aaagcttccg
    24421 ctcccatcat tttgtctatc cacataaata aagccatatc gcttcctcat ttcccctgtt
    24481 cctgccgata cgatatcgat tggtccccac cataagtaac caatgatttg gcaaccatct
    24541 tttattgcct cagcaatttc ctgaagatgt atttttagat actcacaacg ttttggatcg
    24601 tggattcgat tcaattcatc tggtgcttca tctagtccaa tgccattttc aactatgaat
    24661 aatggtaatt cataacggtc tgtcaattca ttcatgacat aacgaaaccc tagaggatca
    24721 attggccaac tccaaggttc gggagatttt tccttcaaaa agggattatc gaaaccattt
    24781 gctccgccag tatctacgcg catttctgct tcttttttat agacagcgct acgataataa
    24841 ctaaatgcaa tataatctac cgtgttagct tgcaagtact gttcgtctcc atctaacatt
    24901 actggtgcac agtcttcttc cttccatatc ctgtaaatat aagctggata atgccctcgg
    24961 cacatgacat cggagaaaaa ccatgaattg cgtttaaatt gcagtgaacc aaatacattc
    25021 tctggatcac agtcatatgc ataagtcgct aatgcagaaa agctacacat aatacccatc
    25081 ttagcatttg gatcgatttt ctttaataat tgagtagcac gggcgttcgc tagaaacata
    25141 tgatgacagg cttgataaat ctcttttttt gttagtgtag caatgggttc aagtttatct
    25201 ctagcaggga atgtaaccaa tccagcagct gcataaggca tacgaaaagc attattgatc
    25261 tcattaaagg tcatccaata tttcactttc ccttggtagc gttcaaagac ggtctgcgca
    25321 taaaattcaa aaaagtcgat taattttcga ttttgccacc ccccatactc tcctaccaat
    25381 gctaaggggg tttcataatg actaagagta attactggct cgatatcata tcgatttaat
    25441 gtattgatta gtctgtcata aaatacgaga ccagcctcat ttggcttctg ttcgtctcct
    25501 cttggaaata ttcgtgccca tgagatgctt gttcgaaaag cttttaaacc taactccttc
    25561 agtaaacgaa tatcctcttc aaatcgatga taaaaatcaa tcgcttcatg agaaagataa
    25621 tggagtgatt cgtctaaagc aatctcccaa atcttttttt cttcattcca ctgaatacta
    25681 ggatgctggt tcatgatccc gataagcgta tctgtcacat taggtaattt gccgtcttcc
    25741 aaccatgcac cttcacattg attagcagct actgctccgc cccataaaaa attttctgga
    25801 aatatttcct gatccataac tatctctcct cgctatcaac aatttcttac ttgaagtata
    25861 gctcgattca tcaaaacaag atattctaac tatttcggca gaagagaaga aaaaaattga
    25921 atgctactct tcatttttaa tatttatata taacaaatac ataagacgat ccccgaaaga
    25981 aaacactcgt taaccatcta agcaaacgat ttattttact tccaacacaa atgcttcata
    26041 aggtcgtaaa tcaactttgc cgtctggtaa ctgtttcaga ggataatttg acacaataac
    26101 ccttaaagct tcacgtggaa cagtgaacgt ctgcttttca ctggacatat tacaaataac
    26161 gagccattgc tggtcttcat atatgcgaga ataggcaaag acatgctcag gcgtcttttc
    26221 cactaattca tagtctcccc agacgatgat gtcatgtttt ctacgcaaat cgatcaattt
    26281 cttgtacata taaaaaacag aatcttgatc tgctaacgct tcttctgcat tgatttcttt
    26341 ataatttgga ttgactcgaa gccatggaat tccagtagta aacccagcat gttcacgggc
    26401 gttccattgc ataggcgtcc tagcattgtc tcttcctttc gcattgattg attccaagat
    26461 ttcctctttt gtaaatccag aagaaatcct ttcgttatac atattgattg tctcaatatc
    26521 ttttgcttcc gcgatatcat cgattgggca attcgtcatg cctaactctt ctccttgata
    26581 gatataaggg gtgcctttca tcatatggag caagatagca aacatcttgg cactttcttt
    26641 tcgatacaca tcgtcatttc cccaacgaga aacaattcgc ggaagatcgt gattattcca
    26701 aaataaacta ttccatcctt catcacctaa agatgtttgc catttggata atactttttt
    26761 cagttcagag atactcaagg gtttcaaatc ccatttgtct ttgccttctt gctgatctaa
    26821 tcctatgtgt tcgaattgga agaccatgga taattcattt cttttaggat tggaataaag
    26881 tttagcgatt tcggtagttg ctccccatgt ttcgccaaca gtcatcagat ttttgtcacc
    26941 aaaagttgct tgattcattt cctgaagata ctcatgcagt ttaggtccat tacttgtgat
    27001 ttctttatcc ggttctttgc caatcatatc gatcacgtcc atacgaaagc caccaatacc
    27061 tttatcgatc cagaaattca tcatttgata aatctcttgg cgaacctgtt tatttttcca
    27121 attcaaatca ggttgacgct tgctatacaa gtgcagaaaa tattgccccg ttttttcatc
    27181 caactgccaa gcagaaccac tgaatattga gcgcaatcta ttaggctctt ttccattgac
    27241 cggatcacgc caaatataat agtcccgata aggattttct ttatttttac gggcctcaat
    27301 gaaccacgga tgttcatcag aagtatgatt caccaccaga tccatgatga tacggatatt
    27361 tcttttcttt gcttcttcaa tcagttcttc catttcttcc atcgtaccga attctgccat
    27421 gattgcttga taattactga tatcataccc attgtcatca ttcggagact cgtatactgg
    27481 agaaagccaa attgcatcaa tacctaaata cgccagataa tccaacctgg aaataatccc
    27541 ccgcaaatct ccaataccat cttgatttga atcttgaaaa cttcttggat agatttgata
    27601 aacaactgaa tggtgccacc atttttgttc catgattttc ctcctataaa tggatgtttc
    27661 tattttttgc ttaatcattt attttagtct ctctcactaa aaattgtaac gctttcaaat
    27721 agctattgca ccttgttatc ggtaacagaa taaaacaaaa aaacagctga ggaaattccc
    27781 tcaactgttt tttgaaagga ttgatttatt cagggaagaa tgctgatttc acaacttctt
    27841 tataaacggt gttcactcag ctgtccctcg gtattagctc aaaaaacggc aaaatataag
    27901 aaactatttt tttcgttttt ttctctaata ctcaggccag aacactgatt tcacaacctc
    27961 tttataaacg gtgttcactc agctgtccct tggtattagc tcaaaaaaag gcaaaatatg
    28021 aggaactatt ttttcgtttt tttctctaat actcaggcca gaacactgat ttcacaacct
    28081 ctttatttca cattcaatat ccacatgaat cccatgaata caaagaacag accatacatg
    28141 atgggagata cttcttttcc tcttttagct gctaacatgg taattggata gaagataaaa
    28201 cctaatgcaa tcccatctga aatactataa gtcaaaggca tgccgatcaa gatcaagaat
    28261 gaagggatcg caatctctaa gtttccccat tcgatttgtc gcaaagattg tgccatcaat
    28321 actcctacca taatcaatgc tggtgcagtt acttgtgaag taacaactga tagtaatgga
    28381 gaaaagaaca agcctaacaa gaagaaaatc cctgtagtaa tagctgtgat acctgaacgt
    28441 cctccaacgg cgataccagc tgatgattct acaaatgcac caacaggaga agtacctaat
    28501 aaggaacccg caagcatagc tgttgaatca gaagctaaag ctttccctac acgaggcatc
    28561 ttgttgtctt tcatgaaacc tgcttggttt gctaatccaa ctaaagttcc tgctgtatca
    28621 aagaaagtca caagcaagaa tgtcagcact acgacccaca tttgaagaga attgatgtcc
    28681 cctacatgtt ttaatgcaac taaaaatgtt ggtttcaaac ttggtgctgc ggcaacaatt
    28741 tcagaaggca ttggaatcaa acctgtgacc agacctaaaa tcgttgtagc tgccatcccg
    28801 atgaagatgc cacctggtac acgccgaaca agcaagatag cagttacgac taatccaaaa
    28861 atcgtcaacc aagtagaacc aacgttgagt gatcctaatc ctactaatgt agattcattc
    28921 gaaacgatga tcccaccttc gctcagacca aggaaagcaa taaatagacc gataccgcca
    28981 gaaatcgcat atttcaaatc tgctgggatc gcatcaatga tcatttcccg cagcttgaag
    29041 attgtgatca aaataaaaat caaagaagca acgaatacgc cggctaatgc tgtttcccat
    29101 ggaatcccca ttcctaaaca aacagaataa gcaaaaaaag cattgatccc aagagcaggt
    29161 gccgttccaa ttggataacg ggctaatacc cccattaaaa tacagccgat cgcactggct
    29221 aatgcagtcg cagtaaacac tgctccttca tccattccag aagcacctaa tacagttgga
    29281 tttacaaata agatataagc cattgagata aatgttgtaa atcctgccag tacctcacgt
    29341 tttaccgtgg tgttcaattt ttctatttcg aagtaggaaa gtattttttc cttcatcttc
    29401 catcccccta aatccgaaca ttataaataa agtccgttaa aatttcgatt tattaataaa
    29461 acaacgtgtt ttatcatata ctaaaacaaa acataagtaa acaaaaaatt cggattttaa
    29521 gcaaaatccg aacgttccat ctgattaaat ccctttatct caaagttcat gaacattcac
    29581 tttggattac aagaatttct ttattgtgtt aataaagttt cttcattcta gtctcaaaaa
    29641 tcaatagtgt gatttgattt taccatttcg tttctgttct tctttgatga attcttttgt
    29701 atcgacagga ttcagattat ttagtccgcc aaaacctgta tcgaccattt ttccccagcc
    29761 ttttgtcttc ttttttcctg atttgagatt ctttgctcga agcttctcac tatgttttgc
    29821 tcgccgatac ttcaaataac cttctaatct tcccattaga tccactgttt ctcctccttt
    29881 ttattcaatc agacgactca gcttttccta taacaaaata attgccttca gggtccgaaa
    29941 aattgaaagt caagacgcca ttgttgtctg tgatttctcc tggttcttcc atgttctcgt
    30001 agatagtttc aaattcatcc gtaaaaaata ctaaagaagg cggtggtcct aatacctctg
    30061 gtgaaaactt ctgcacaaat acttttggga atacgcctaa ttctaattct tttgagatgc
    30121 tgagtacaat actcttaaat tcttctggca attcgattgt ttcagaaatt tctgcaccaa
    30181 ttttttctac aaagaatcgg caaatcatct ctacgtcatt gacataaagc atcacacgtg
    30241 ttttttgtat catcgtttga cccttctttc tatttgattt tctttcctgt ctataaactg
    30301 attccattat atcacgaaag cgcaaacacc ttgtgtttga tactattcaa gaaaaataaa
    30361 gcaatagttt ctaggattgc tttcctccac aaactttttt tacaaaaaaa aaacggcaat
    30421 gaatgccgct cttcttattt cgattctttt ataattctgc ttctgattca tctttggtta
    30481 gtgtgtgtct aacactagtt acgccaaatg tttgatcgat tttttccttc aacgcttcga
    30541 ttgcctgtgc gccacgtgcc gcttgttcag cattgatgga ttcaatgacc agcaccgctg
    30601 cttgtgtttc ttccgtcagc atcgttcttt gggcttcacg ccagttgaga cagcgacaga
    30661 tcgctccttg ttcatcatag tagatgattt cttccggaag tgccggagca tcggaatctg
    30721 cacctaaagg caggaatgat tcgtcacctt gggcttttcc taaatgcaga tttcctgcga
    30781 tcttttcgat atcttctccg ccgcaaggta cgccaaaaga caaggaaata ctattataga
    30841 tatctacaag cggattgatt gggaaaaatt cccgttcttg atttgcacgt ttcagtaaag
    30901 cttcaataga agaacgtgca ccttttttag tcttgaatgt ggtaaatgcc tgacgccact
    30961 gagcaatgac ttcgttttgg ctgaatgttt cttctgtaag gtaatttctt gcttcttttg
    31021 ctgcctcatt caataattga tgatacgttt cttcactttc ttttgttacg tggttatcga
    31081 taccatttac ggataagatt tcgatggttg cttcaggaaa tacttcccag aaattggtat
    31141 ccactattac ttttttcatc tgttcacacc tcttgattag aataattgct tgatgaatag
    31201 atagtctgtt tggggatcat ctcccatata aaaaacatgt tcgctgtatt tgataaatcc
    31261 ttttttacga taaaaagcga gcgcaacatc gttgtgttcc caaacaccga gccaaatggc
    31321 tgttttttgc ttttcttttg ctttttcaat agctgtatct agtaaaaatg taccgatacc
    31381 ttgatgttta aatttttttc gtacatagat tcgctcgatt tctaaaaaat gatcagccat
    31441 ttcctcagat tgactcgttc ctgtatttag tttcaggtaa cccgcaggct cttgatcgat
    31501 actcactagg aaaaaatctg tttctttatc ttttagctct tctgtaagtt tttctagtgc
    31561 ataagcttgt gtcaagtaat cagctaaatg ctccggtaat tatcttttcc aaatgtatct
    31621 gtaaatgttt cgatactaat ttgttgtagt aagtctacat ctgaaggcgt catttttcga
    31681 atttcgtatt tattcacggc ttcttccttt caatagatcc ttttattgcc ttttttgaca
    31741 aaattccaat cttcgctaac attcttgcat actttattta aaagatattc caattgtttt
    31801 gcttcttcgt cagaaagacc atttaatgcg actgcattgg agtagttgtt ttctcgaatg
    31861 atgaaaggat agatttctgc tcctttttta gtcggataga gtttcttgat ttttttattt
    31921 tctttatctt ccaaacgttc gatcatccca ttggattcta atttcttgat tgctcgggca
    31981 gtcgttgtac gatctacttt gatcatttct gctagttttt cttggatgat tccaggattt
    32041 tcgcaaatac gtactaaata aagatactgt cctcttgtta aatcgacttc tttgaattcg
    32101 atattgctaa tagagtctag cgctcgggca atcattccga tgtctcgaag gatttcagcc
    32161 atttcatccc acctttattt tgtttgtaag actagtttac ctctttttgt tgcaaatgca
    32221 actattttta ataaaaaaat caagttcttt tttaataact agtaaagtat attcttttct
    32281 tcttttacga aaaagctcaa tcacaataga tctggttttt gttttctaaa ataagtaact
    32341 gtttcttcgt tgttcgcttt tctgatagct ttggcaactc ttctatacta aaaaatccca
    32401 tgttggaagt ttcattattc tcaataaact tggcctcttc accgtggatc gcacaagcaa
    32461 aaacaagttt ataatactga aaaagctgtg gaatatcttt ttgtttattc gtatcaaaaa
    32521 ctgctcgcaa ctgagtagtt tctactgtta atcctgtttc ttcatagact tctttacgca
    32581 cattttcttc aggagacaat cctatttcag caaatccacc aggaagtgac cattctttcg
    32641 tccgtttatc ttcgattagt aggaccttgc catctttttt gatataggca cgaacatcta
    32701 cttttggtgt tggatgtcct tctccaatcg ttgtgagcgc ttttatttct tcgaaagttt
    32761 cttttcctat ttcactgatc agttccaatg aaatcgtccg gatctcctca aaacgctctt
    32821 tatcaaatac atcttttcca taatatagac cagcttgaga aagtgcgagt agtcttttgt
    32881 attgagccaa cttcttgttc attctcttcc cttctttttt agcaaatgta tgactatgta
    32941 atcaagtata gaagactggt ttaattacgg caaataaata taatgaaatc tgcaataaat
    33001 aaaagaatgt taaaaaactc gagaacaaaa gacattcgac ttctctgggg ctgtgaataa
    33061 atggcgttca aaagcttgca tctgcggtaa taagccccat caaacgaaaa atatgacgag
    33121 ctattcttgt ctggctgttc ttattaattg aggcaggaca gctttttcac aacctcccca
    33181 ctaaacggtg ttctcctacc aactcctcgg tcacaagtca caatattcat caaacatgag
    33241 aagctgtttc tttgaaattg ctccttgtga ctcggagctg aacgacaggc tcacgacctc
    33301 tcggtaaacg gtgttcaaaa gccaattttt cgatattaag ccatttcttt gttacttatt
    33361 gtcattgatt tctttttcta atttatccaa tagtggagtg taatccactt gagtatagtc
    33421 tgttacatca aattcatata gtgttcctaa ctggaatttg tcatattttc ggtcggcgat
    33481 gatctttttg aatgcttctt tcgtaatatg attggtccct ttcgttcgat cttccaatac
    33541 gtcaccatag tgataatgat ccatgatata gctcaaatga cgatctgatt cacgatcacg
    33601 tttgtaccga cgttgccata acacttcaaa gtctgctgtt aggcgaatcg tgatcacctg
    33661 atatccgtat ctatctgcta attcttggag tcgtgctttt tgcttatcac taaaaggata
    33721 ctcggacaca atcactttct ttcctgcttc catatacaaa tcaagtgctt tgtaatagaa
    33781 aggataaact ttcgtccttt cttgttccgc ccgttcttcc aaattgttaa acccgatgga
    33841 ttctgcatag tattccttga tttcatcgag cgtgatggca tacatatctg gaaatcgttc
    33901 ccgtagttta ttcataagat atgtttttcc tgtaccagga ctaccagcca gaagaatgaa
    33961 atactttttc atctcattta tttcctaagt taattggact ttccaagttc ataaacagtc
    34021 caatcttatg cttgacaatt tcttttactg ctttatttgc tggaatcaca ttatggcgaa
    34081 gagacttgtt gatttctgtt tcactaaagg tttctttagc tactttcgtc cagttgacta
    34141 aaagctccgt tccaacattg aatttgcgga tcccgttatt gatcaattca ggataatctt
    34201 cttctttcac acctgttcct ccatggataa ctagggggac atcaactact gcatcgattt
    34261 ctttcagcaa gggaatgttt acttctgttt ttgatttgaa ttgtccatga ttcgtaccga
    34321 tagcaatagc taatgcatcc acgcctgtag cttctacaaa tttcactgcg tcttccggtc
    34381 ttgtatatac cttgtcattt tcagcgacat ggattccttc ttctgtaccg ccgattgttc
    34441 caagttctcc ttctacggaa acaccgtgcg catgggcata ttctactact gcttttgtct
    34501 tcaagatatt ttctttgaaa ggtagatggg acccgtcata catgacagaa gtatatccgc
    34561 tatcgattgc ttctttgata tcatcaaagt ctcgggcgtg gtctaagtgt aagactgcat
    34621 caaccatttc ttcttctgca atagctgtca ttacattgac taacacatgc atgccgatat
    34681 atttagcggt atcgacactt gtttgaataa tgattggcga acccatttct tttgctgcgc
    34741 ctagcatggc aggaagcatt tctaggttat gcgtattaaa agctccaact gtaaaattca
    34801 actcttctgc tgtttttgtt acttctttca atgttgtata catcttttat tgccacctta
    34861 tctttttatt tgtttccttt gatcgttact tgttttgcaa tttgtcgcat ctcatccatt
    34921 ttgcccatgt agtaatcgat cccttgatca tcaccagcac gagcagcatc tgcacgcttc
    34981 tggttataga ggctcatcag ttttttatac ccatctccga tcgtctgttt attttccaag
    35041 ctcttttcta aatattggat ggcttgatcg ttctcatgca attcagaaaa tttaagtcca
    35101 acttgttcat aaagttccgc taatttatgc ctatcttggg tagtggaaat ctcttgtttc
    35161 aattgtgtaa tctctgattg aatcttttcg gtcgcttctg gcgatagggc tttttcttct
    35221 tttgccagaa cttttttcgg ttctttttct tttttcttaa aaaatccaaa catcattttc
    35281 cctactttca attaaaacgc tttcaaaact gggcttaaga tccaggcata taagagtgct
    35341 gcggctactg tatctacatc ggttgctgta gcattgatga atcccatcga attaaagatc
    35401 gttactagca aagcgggcaa taatgtaata aagaaaccat gagcaatacc gccaatgatc
    35461 gctcctcggc gtccgccaac tgcgttgcca aatatccctg ctgtccctcc ggcaaagaaa
    35521 ttggttagca taccaggtaa aatcatcgct aagccgaaca tgggcaaagt aaacatggca
    35581 ataatcgtac caatcgttgt cgtaatgaaa cctaaaatga cggcatttgg gctataagga
    35641 aagaaaactg gacaatctaa ggcagggatc gcatcaggaa ctaatttcat agctatccct
    35701 cgaaatgccg gcacgatttc acctaacagt agacgtacac cagctagcaa tatatacaca
    35761 cccactacga attggatggc ttgtaaaaag gcaaacatga tatagttttg atctcctgat
    35821 aattcagaag cgaatggttc gcctgcaaat aaaacagtga tgatatatag cgggaccatc
    35881 acgaccatga cagacaaata agtatcttgc agaaattcga aatgtgtcgg caacttgata
    35941 tcttcgatcg actttttatt ttcgcctttc tcaccaaaaa gcttagcaac accggcttca
    36001 aataagtacc cgatcgtaca aaaatgacct aaagcaatat catttgatcc agtgatttta
    36061 cgaatgatcg gttgcgctac tgccggcata gcaatggcga aacaagctcc gataaaacca
    36121 ccgaccaaga tcaatacgat ccctcgcaga ccggcaaaat agccaaagac tgtcgtcatc
    36181 gttgccatcc ataaaattgc ttgaccagtt aaaaaaatgt acttccattt tgtgaaacga
    36241 gccaaaataa tattgaatac aaaaatggct aagaacgtca gtgcaatatc tctacctaaa
    36301 cccaaatcat tcattgcttg atcattgata gattcaatag aagggatgat cccttgcata
    36361 tgaaatcctt cagtaaagat tttcccgaaa taagttaaac ttccaacgat gatgctcgaa
    36421 ccggcactca atacttgaaa tcctaggagt gtttttaacg tgccagagat gacttgtcct
    36481 gctgatttct tctgcagtag tagacccaac atagcaatca atgcaatggt gatcgatgcc
    36541 tgagtcaaaa tattttcgat gataaaattg ataacgctca tgtttttacc ctcttttctt
    36601 tttgtattta gataactccc ttatcttgca gaactggggt gattttttct tcaatttcat
    36661 tttttgaaac aatatttttc aaatagatca tcgccgtttt aggatcaact gcgaactttt
    36721 cgaactgcga acgaaaattt tctgctgtga tgatcacatc tggtttcatg gaaactgcgg
    36781 aagaaatatc acaatggtcc agtttggctt ctactcctaa tttgttcaaa acatcctcag
    36841 cagacatctg tgctgcaaaa ctacttccta aacctgcgcc gcatacgaat aaaatgttca
    36901 atttgttcat ctttgttctc ccccgtatca tttattattt ctcaactact gaaaaaagca
    36961 gttgtttgaa atcttcgata tttgtgcatt caatcaatcg atccaacttc tcttcgttgt
    37021 tgatcaattc aattagttct ttcatgatgt tcagatggga gtaggagtct actgctgcca
    37081 aacaaaaaat aatctttact ggatccattt caggattacc gaaatcgatt ggttgctcaa
    37141 tcgtagctac gctgactcct aatttattga ccccatcttc tggtcgggca tgggctagtg
    37201 ccatgtgttt gccaatcacg atatacggtc cgtaatcatt cactgcacga atcatcgctt
    37261 cgacatagcg ctcttcgaca atgttttctt taaccaatgg tctagcagct agttcaatcg
    37321 attcctccca agtagtggct ttttctttga tcatgatatt gctgtccgtc aaaatatctt
    37381 ttaacatagg ctggatctcc cttttgttga tttctaaatt gtttgtttcg aataattttt
    37441 ctaacttgcc atagatgatt cgatctactc ggccaccact ttctttcatg acatctatta
    37501 tttgagtgaa taactccgtc gattcatgac tgttaggctc taaccgctgt agttcttcat
    37561 ttcttttcaa aaagtcttct ataaccaaga tattcgtctc agttaaaatc ggatcgacaa
    37621 ctaaaagcgg cttatttcga taattcaatt gaaaggtgct gaaaaccaga ttgacatcca
    37681 atttatctac taattcgatt tcttttgaac ttaaaactgc agtaatctcg atctgaggaa
    37741 acttttcttt cagattctct gctaacagat ttccagtagc catcccatgg ttacagacaa
    37801 cgactgattt ataaacataa ttcaagtctc gcttgattac actggcgatc gtcgaaaagt
    37861 ggatgacaag aaaagctatc tcgtcctcca gtatcttgcc accaattact tcttcgatcg
    37921 taggaacaaa atgagtgact gcgcggtaga ttgggaaata atttgttcgg atgttttctt
    37981 tcaatggatt catgacttgg atatgattct tgattcttac aatcagtgca gccatgtgct
    38041 tatagagatt ttcgaataag gcttcttcct ttagatggaa aggtacgtgt gtctcgttct
    38101 ctacaaattg gatcaattgg atcgttagta attgagcttg tacccactcg attgaattgg
    38161 agatatctct agcattgaac gtctcaatag tgaaacgaag ataatttctt tctacttgcg
    38221 ggacattgtc caattgaaat tcctcgatca tgtggtcaat aaatgcagaa aagctactgt
    38281 cttttatttc tgtatttttc caattaatgg cagagataaa ttcatgtttc ctgattcgct
    38341 ggatccagat caatgtaaaa agcaggattt gttttttata aatatcatct tcttgtttca
    38401 acaacttatt ggaatagatc tcctgtattt ttttgatttc ctccaaagga aaataatgga
    38461 gaaagatttt ttgagccggt gttaattgtg catcttgatt cataaagaag tcggtcattc
    38521 ccagattctg attgataaaa tcatagatca tcgtacggat agatcgttct gaacctttat
    38581 aaaccagtcc ttgctttcca taactgacga tctctatccc ataactgacc agtgttgctc
    38641 gtaaccgtct catatcttca tctaatgtac ttttagagat ttgaaattct tcttcttttt
    38701 tgtttagatg gatcgggatt cggctgtaag caacggctaa aactagatca aaaatacgtt
    38761 cgcgccgatt caaaaagccg tctttcacat cttttatttc agtttctaat cgagcttgct
    38821 tttccttttc cagcttcaac aaaaaacctt tgttgcgaat tgtacggatc tccggaagct
    38881 ttttactgct caaccagata ttcgcttcaa gaacttcctg acgaatcgtc cgctgactga
    38941 cattgaactc acttgctaga tgttttgctt ttactggata ttgggctgtc atgattctgt
    39001 gaagtatttc aattgttctt gttttcatag aaatgatctc cttctgattt caagtatatg
    39061 gttccgctta cataataaaa agtagatatt tctgccactt gaagtggaaa gaaagtaagc
    39121 aaagcaaaca aaaaataagc catatgcttt ttcatctcct caacgaaaaa gacatacgcc
    39181 tattattaca aaaattttgc ccatctatac aaaaaagagg ttgtgaaaaa gctgtcctgc
    39241 atcaagtaat aagaacaact aaactaaaat agtgcttcct attttttgtt tggttgttct
    39301 tattatcgca gatgcaagct tttaaacacc atttagtgga gaagctgtga cagagatgtt
    39361 cagccttgag cgataagaag cgattttgaa aaatcgcttc ccatatttta caaaatcgtg
    39421 ccttattgcc gataggctat ctctggaaca ccgtttattc agaaaaagga gctgcgacaa
    39481 ggcttttgtc acaactccgt tcataaatat ttcctgtcaa tccagcataa tcggttgaat
    39541 aaaatcggct tgccatcttt tttctttctc agaaaaatca aaataccata tctgagaaaa
    39601 atactgtcgt tgtgtcttac ttcctgagat caatcgccca tcttttcgat cgactgaata
    39661 atcacagcat ctgaaatcaa ttcggatggc aaaactattt tcgtggatct gtcgataatt
    39721 tcctacttcc tgaatagtta tttttttagt atgatttctt acaccgtctg ctttgttttt
    39781 ttgcagaact ttctgatgtt cggcaaacag cttgtctgta taacagcttc tggctttttc
    39841 aggagtttct tcttcccaag cggattggat cttcatgaat atcttttgga tttccaaaaa
    39901 ctgtgctttc ttttctttag ccgttcctga catgcgggac aatatctccg atttcagcct
    39961 tttcttttgt cttttattct tgacgataga aaaagcagaa acccctccta ctgacaaaac
    40021 agctaatgca agaaaccccg tttgctcata actagaagga cctgtacttg gaccataata
    40081 cccataagaa tctctgccgt aagaacgact gccaaaataa ctgcccccat atgaacgacc
    40141 gccaaatgaa cctctgcccg aacttcgacc gctagatgta cctccaccat gaccacccgc
    40201 gacagcgaat ccttgggtcg gcagagcaaa caaacatagg cccactaaca aaatgattgc
    40261 taaataattg attttttcat tgtcttcctc gttatctttt attacaaaaa actattttta
    40321 tcatagcctt gctaaaagga agagtcaata accagatgca taaactgttt ttttagcaat
    40381 tttgtcttat ttagtcattg agtaacatcg gacagatgta tgtgtcggca gtccataatt
    40441 cctctatctt cagcatgaac aagcttgcag acaagagatc tgcgcttcct ccaggagaga
    40501 tttggttttc ctgacaaaag tgcaacagtg ctgtaaatgg acgatttggt aaagcacttt
    40561 gactagcagc atgagcaagt ttttgcattt ccactaacgt tttctgatca ctgcgatgca
    40621 atacgcatgt gtcatctagc gaactcatca aaactaacaa catatgcatt tgtttctgta
    40681 catatgaatc attatctagc tccttagctg cttggattgc aagcctgata tgcggatacc
    40741 ctaatatcgc ttcttcatat gcaccattta cgccatattt ttgcttcacc ctatgaccat
    40801 gagtggtttt tttatgacga tattttgtat caggaaaagc agcaagcttg ctgacatcat
    40861 caagtatttt cgataaagaa aaaggctgtt ccatactgat tttttgtgca atgacactga
    40921 tcaatagccc cattgcccaa atcgctcctt tatgggtatt gatgccattt gtagcaatca
    40981 gcattgcctt ttccgctttt cgcccaatct cagcaattct ttctcttaac tcctgatcaa
    41041 tagcataatg ccatgctatt tgagccattt cttcaaaaaa aggagttagc gtcttagcag
    41101 acttatccaa aatgcgccga ccttctttta cggcttttgc gatcgtatgg aaattatcat
    41161 ctcctaaaac catatcagct gcctgtttgc ttacttcact acctttgatt cccatagcga
    41221 ttcctatatc ggctcttttc aaagcaggtg catcatttac gccgtctccg gtcattccga
    41281 cgatttctcc atttttctgc aaagctttca cgattcgcag tttgtgttct ggtgtcgttc
    41341 gagcaaagac gtcgactttt ggtacttgtc gaatcaactc ttcttcagac ataagatcca
    41401 aatcgatccc ttctaaaact ttagcagtat gttttaagcc aatttgttcc gcgatcgctt
    41461 ttgctgtatc tttgtgatcc cccgtaatca ttttcactga gattcctgct tgttggcatt
    41521 cctttacagc tttgactgca ctttcttttg gcggatcaat caacccagca atccctgcaa
    41581 aagttaattg ggttaaagac tcatgcgtga gttcctgttt cgaatctact tttttgtaag
    41641 caaatcctaa aacacgctga ccttttttcg caaacgctgt ggctgtttga ccccatgctt
    41701 cttattctga agaagaaaga gttgatttag ccaataatac ttctggcgca cctttgacgt
    41761 aaatcacccc tcctttttcc tccgcatgca tcgttgccat atatttgtat tcagagctga
    41821 acggaatttt tgcttctatt tttttcaaag gcagatcggc tgtttcggtg tggcgaatca
    41881 gtgcaagttc tgtcggattg ccacttaaat tttctgtttt ctgttcttct ttcgtcttta
    41941 attcctgaca atttttcata ataaacagta cgcgagtttc ttcctttgct gctacatcca
    42001 caactgtcat ttcatttttt gtcaatgtcc ctgtcttatc tgaacagatc actgtcatag
    42061 aacctaatgt ttctacagaa ggcagtcctt tgatgatcgc cttttctttt gccatttcat
    42121 gtactccgac agataggatc atggtcaaca cagctggcaa tccttcgggt accattgaca
    42181 ccaccaaagc gatcatagct gaaagaagga tatgccaatc catgccatag cggaatgttg
    42241 taaaaacaac taagaacaag atcaaacaaa gaatgccttg aaaaatttgt ttgttcaatc
    42301 ggttgatctt cttgatcaga ggcgtcgttt gttgttcgac cgattgcagt gcttgattga
    42361 ttttaccgat ttctgtcgtg tttcctgttt ctacaacgac accgactgca gaaccagatt
    42421 gtacaagcgt tcctgaaaaa gccatatttt tttggtcacc gattgattct tctgctgcca
    42481 aaacggaatg atttttttca gatgcttctg attctcccgt caaaatcgat tcttctacta
    42541 gtagatcatg tacttcgatc aaccgaacat ctgctggaac gacgtctccg gcacgtaaga
    42601 caatgacatc tccttttact agttctttcg cagggatttt ttcttgcatc ccgttcgata
    42661 gtactatcgc ttcttgtccc atcagctgct tcaaaccatt caacgattct tctgcttttc
    42721 tttcttgcca ataactaacg agtccgttga cgatcactac gaataaaata atacttcctt
    42781 cgatgtattc gctcgaagca aatttcaaaa aagaggcaat gatcaacacg atcatcagca
    42841 gatcagtaaa gtgttttgct atttttttcc atcgttttgt ctgctgtctt gcttctatct
    42901 cattatatcc ttgatcagtc aggcgtttct gccgttcttc ttgcgacaag ccttctgttg
    42961 atgtttgata gtttttcaat acatcttcta ccgtcaatct gtaccagttc atcctatccc
    43021 ctcctgttta attgatactg ttattatacg cagggaagtt ttttcaggcg tatcgattat
    43081 ttcagggggg tctgaaataa ttcgttttgc agaatgtatc tgggcctaac tgatatttct
    43141 attgcttatt cttttatata caaaatttaa gaatacaaac cagataacca ataaaaaagg
    43201 aataaagcgt gtcgtgcttt cgaataacaa gctgaaagca attgaagtaa aaaacaccaa
    43261 caaagcaaga tctttatatc tttgtgtagt gttccgtttc ttttctttaa taaattgaac
    43321 atgtgcacac aagatcgaag accacacaaa tagaaaacaa ctcgttgtca tgcctgccaa
    43381 aagctgaaaa aacaatcgac tatcagctac aaaaaaatgt agacaaagac cgacaaaaaa
    43441 taacatccct gtaattaaaa taccgtgtaa aggtacgcct ttcttagaaa gcgcacaaaa
    43501 ccaatggggc aaacttttct cttttgctgt ttgatataaa atcctgctag tactgtagac
    43561 tgcactattt gctgaggaca aagaagcaac caaaatcatt agattgacaa ttgctgctcc
    43621 gctttggcaa tggatcactt gcagcatagt cactaaagga ctttctttta aatctaaaca
    43681 atgccatgga acaacaaata aaatcgacaa aatcgttcct atatagaaaa agaggatacg
    43741 ccaaggcaga cagttgattg catttttcaa attcttttgt gggtcactcg tctcaccaac
    43801 tgttaatccg atcatttcaa ttccagcaaa actgaataaa accataggaa atgaagcaat
    43861 cattccagca aagccaaacg ggactaattc attgagctgt ccaaaatttg ctttgattcc
    43921 aatagactgg gtatgaaaat ctgagacact caatcctata cccaataaga taaaaaggaa
    43981 aatccccaag atcttgatga ttgagaaaaa agattccaat tcaccaaacc acttgactgc
    44041 aacaaggttg actgccatta agatcattag tgcgctacct ccgcttatca aagctggtac
    44101 atgtacaaac cagaaatgga tatacaatcc tattgctgtt aattccgcaa gtccagctcc
    44161 aagccagcaa agccaataag tccaattgac aaaaaatgcc cactttttgc ctaaataata
    44221 gtcaacgaaa tcactgatag agttaaatgt actatttgct aaaaataaat cacccatgac
    44281 ccgcatcaaa ccataaatag ccaaaccgca tatcaaataa acgagaataa cagctggccc
    44341 tgctgatgca attgcctttg ctgaacctaa aaataatcct gttccaattg cgccacctaa
    44401 tgcgattaac tggatatttc gattagttag agtccgtttc attgccggtt tttccatcaa
    44461 gttcaccttt ttctttttca agcagcatgg cgacttcctg ttcccaagaa ggtttcttta
    44521 ttttttcaat acagagtggt actacaaaca aaatgacact gatggctgtg actgcaatta
    44581 gattgatcca tgtcccagct ttcatcgtca gtccgacaga aaatccgatt gccgcaaata
    44641 aaacaataac gacagtccaa actccaagat tgctcttttt ctcttttttt ccaattctaa
    44701 atggtcgatt caactttgca tgtgtataac gcaatctcaa aactgcgatc cccatgatga
    44761 catagacgat acagtagata acagtagttg aatttacgag catcaaaaat gcttgattga
    44821 cgccaggaat cagcaaataa aaaagtgcaa agattgagat aatgacagac tgagtcaaaa
    44881 taacggattt ggatacgtca aattgattcg tcttccaaaa attgaatttt ggtggatacg
    44941 caccttttct agcactttct gtcactgtct ttgctggtcc tgaggcccaa gcagataatt
    45001 ggactgctac accaatgaag acaagtaaac taaacagatt cacaataaga tgtggcaaac
    45061 caagaatttg gcaataaatc gaaatagatt gcgcgatatt attcaattcc atttgtcctt
    45121 ttggtacgac atttgctaca actaaagcat tcaaaatatt gacgaaaaat ataaaaatta
    45181 acgcggcaaa tactccgcga atatacgttt taactggatt tttcaaccga gtgatataca
    45241 cagaggacat ttcgatacca gtaaaaataa acatgatcgg cgcaaaataa acaaatgagg
    45301 atgcagtcgt agtatctggt attaatttgt cccatgaaaa actgcctaat gttccggttg
    45361 gtacgatccc aactttgatc cacgcagcaa accctaataa gagcatcatc gtcaaaggca
    45421 cgtacaatcc taaccaaaca ccgacttttc cgccgatttt tgccatatca aatttcaaat
    45481 tcaaaaaagt gatgatccaa taaacgacta aaatgacaac taatgtaaat ttgctgttca
    45541 aaccaagcgg cacattatcg ataatattac caaacaacgg agcaagtgct gaagcgacca
    45601 tcaccatccc aggaaacatt tggacccata acagccatga gacaacgaac ccccattttt
    45661 ttcctagagc attcgatacc caaagttctg gaccaccttt ttggggaaac attccggcaa
    45721 attcaccaga gatcaatgag attggaaaag cgtacaataa tactgcaacc agcatgtaaa
    45781 aaatcatcgt ccagctcgtt gctgctacat ctggaatatt tcgtacactt gctacaaggg
    45841 cgcaggtcat tccgataaag gtcatggtcg tgatttgctt tgatgaacca gtatctttca
    45901 tctttattcc ttctttcaat agcgacatat gtttttgttt tcttttattt ttgttcaaga
    45961 acagaaatga caaggtttca tcgattcagt acaaaaccca gtatcaccga aacatccatt
    46021 gaacgatctt agtgaactgg gtttgataca tgaaacgaac gatccaactt atagaacgtt
    46081 ttataaaaaa gaatatcttg gcgaggaata tatgaaaaac agggggaaat acaattgttt
    46141 tgatgaagca aataattgtc tgttctccat atgtctcttg ttattctttc acacaaaaat
    46201 cagttctatt ggatgatttc gtttagtttc ttttccattg ctttggcgat ttcttttgta
    46261 taaaaattga aaattcgatc atcattcaaa taaggagtca tgatagccgc acgtagcaga
    46321 gtgattttct gttctttttt ccattcttct ttcgttagac ccattctttc aacaaaacga
    46381 atcggagaat caccgtaatc ttcttgtgta aatgtagtat gagaagtaat aaaccgttca
    46441 ccataaacat cgccatccat ataagaagac cgatcgaaca ttttttcatt taattcattg
    46501 atagcgttca aatctgtaca gccttgttct ttgaataccc aattgaccat attaaaatca
    46561 ggatgattca atggatagac ttcgattgtt tttcctttaa cagtaaaagt cagatgatcg
    46621 agaaattctc tgaatctttg agctgcctcg attgaagccc caatcaattg accatatccg
    46681 gtcacattca atggcaatac acgatgtgct gtccagactg cggcggcggt tgctccagct
    46741 tttgatcctt ccaaaatata agctcctaac atatctggag cctttactga tttttcaaac
    46801 acatatggcg cgaaataaga aatgatattt ctcatatttt tatgtttgat tacgattcct
    46861 ccagcagcat aagggacata gcccatctta tgaggatcta tcgtgacaga atccgcttct
    46921 gaaatagctc tgaacccttc atatacctct ttgtcaatcg ttacgcagtg gtggaaaaca
    46981 tgatgttctt caaagaattc agctaaggaa gcatacggca caaattctcc tgcttcgttt
    47041 agaaacagtg aacgcgcata gccgccatat gcggcatcaa catgtaaata gaaatagatc
    47101 ccttcatctt ttaacctttc tcttaattgg acgattttat ctacactgtc tacttgacct
    47161 tcttctgtcg ttcctacgac agcaaccaca cctagaattg ggattttttg ttcagctaat
    47221 tcacgaattg ttttttccaa agcattaata tccattcgat aatcctcttg aactgggata
    47281 gcaaccatct gatctaagcc tactccgcaa atatctaacg ccttcatcca agaatagtgt
    47341 tttgtttgag gcaccagcca tttccctaat ctttggatat tttttccgct acgggaagaa
    47401 gctgctttga cctcatccat ttcttcgtcc gtaaagcttt cggtcatttc caaaatttct
    47461 tcaacagata aattcaaaag ttcccactca gacatttttt tcacttgttc aggcagcact
    47521 tccttgacag ctaaaggaat cgatttgatg cagcgggcgt accataatcc ttcaagatta
    47581 gcaatagaac catctgctgc aatgtgtccc catccgtctg tcatattgaa taatgaagca
    47641 aaatcctgtc ctacttctgc ttccatttgc gaagttgcca tagaagattc caatgcaaca
    47701 ttatttgggt tccacagcat cgcatagttg taagctaata aagcaggcat caatgtttca
    47761 gcattcattt gtccccagta acggcctgct gaatgccatg ggatcgatcc tgcgcgtaat
    47821 cgctgactga cttcatccaa gacctctatc atatggtcgc gggtggctag ataatctgga
    47881 gtgagcttat ctccttcgct aattgcaggc atatctgaag gaatataatt ttctctccat
    47941 ccaagatgtt catctaccat cttgttcaac aacattttat aaactggtcc attttcagct
    48001 ttgtcgccta taaagacggc cttgatatcc atatctttca tttttcttcc ctccatattt
    48061 tgttggtcaa tgtctcgcag atacatgtgt ttatctgtaa cacctcttca ctatagcgcc
    48121 aaaaatgaga aatttttttt tataacatca aatccacgta gattttta
//
LOCUS       DAXQKX010000018        45781 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.018, whole genome shotgun sequence.
ACCESSION   DAXQKX010000018 DAXQKX010000000
VERSION     DAXQKX010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 45781)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45781)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45781
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.018"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            102..545
                     /locus_tag="ACF3MF_001080"
     CDS             102..545
                     /locus_tag="ACF3MF_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFE3927092.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(551..1735)
                     /locus_tag="ACF3MF_001081"
     CDS             complement(551..1735)
                     /locus_tag="ACF3MF_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HFE3927093.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            2003..2701
                     /locus_tag="ACF3MF_001082"
     CDS             2003..2701
                     /locus_tag="ACF3MF_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFE3927094.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2708..3385
                     /gene="nth"
                     /locus_tag="ACF3MF_001083"
     CDS             2708..3385
                     /gene="nth"
                     /locus_tag="ACF3MF_001083"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HFE3927095.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(3511..4044)
                     /locus_tag="ACF3MF_001084"
     CDS             complement(3511..4044)
                     /locus_tag="ACF3MF_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927096.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(4341..6722)
                     /locus_tag="ACF3MF_001085"
     CDS             complement(4341..6722)
                     /locus_tag="ACF3MF_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HFE3927097.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(6712..7359)
                     /gene="recU"
                     /locus_tag="ACF3MF_001086"
     CDS             complement(6712..7359)
                     /gene="recU"
                     /locus_tag="ACF3MF_001086"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HFE3927098.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            7423..7962
                     /locus_tag="ACF3MF_001087"
     CDS             7423..7962
                     /locus_tag="ACF3MF_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HFE3927099.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            8052..8471
                     /gene="gpsB"
                     /locus_tag="ACF3MF_001088"
     CDS             8052..8471
                     /gene="gpsB"
                     /locus_tag="ACF3MF_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HFE3927100.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            8493..8860
                     /gene="rnpB"
                     /locus_tag="ACF3MF_001089"
     ncRNA           8493..8860
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACF3MF_001089"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9069..10235
                     /locus_tag="ACF3MF_001090"
     CDS             9069..10235
                     /locus_tag="ACF3MF_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HFE3927101.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            10281..11777
                     /locus_tag="ACF3MF_001091"
     CDS             10281..11777
                     /locus_tag="ACF3MF_001091"
                     /EC_number="3.4.17.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HFE3927102.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            11858..12541
                     /locus_tag="ACF3MF_001092"
     CDS             11858..12541
                     /locus_tag="ACF3MF_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFE3927103.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            13186..14376
                     /locus_tag="ACF3MF_001093"
     CDS             13186..14376
                     /locus_tag="ACF3MF_001093"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008890 - glycine C-acetyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HFE3927104.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            14478..15431
                     /locus_tag="ACF3MF_001094"
     CDS             14478..15431
                     /locus_tag="ACF3MF_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HFE3927105.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            15500..16849
                     /locus_tag="ACF3MF_001095"
     CDS             15500..16849
                     /locus_tag="ACF3MF_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFE3927106.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVIAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(17032..17355)
                     /locus_tag="ACF3MF_001096"
     CDS             complement(17032..17355)
                     /locus_tag="ACF3MF_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927107.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            17484..18647
                     /locus_tag="ACF3MF_001097"
     CDS             17484..18647
                     /locus_tag="ACF3MF_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFE3927108.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            18717..20066
                     /locus_tag="ACF3MF_001098"
     CDS             18717..20066
                     /locus_tag="ACF3MF_001098"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFE3927109.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(20111..20542)
                     /locus_tag="ACF3MF_001099"
     CDS             complement(20111..20542)
                     /locus_tag="ACF3MF_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFE3927110.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            20930..23572
                     /gene="alaS"
                     /locus_tag="ACF3MF_001100"
     CDS             20930..23572
                     /gene="alaS"
                     /locus_tag="ACF3MF_001100"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HFE3927111.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            23772..24368
                     /locus_tag="ACF3MF_001101"
     CDS             23772..24368
                     /locus_tag="ACF3MF_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFE3927112.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            24490..25638
                     /locus_tag="ACF3MF_001102"
     CDS             24490..25638
                     /locus_tag="ACF3MF_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFE3927113.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(25676..26089)
                     /locus_tag="ACF3MF_001103"
     CDS             complement(25676..26089)
                     /locus_tag="ACF3MF_001103"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HFE3927114.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            26168..26599
                     /locus_tag="ACF3MF_001104"
     CDS             26168..26599
                     /locus_tag="ACF3MF_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HFE3927115.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(26698..26931)
                     /locus_tag="ACF3MF_001105"
     CDS             complement(26698..26931)
                     /locus_tag="ACF3MF_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFE3927116.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            27114..28784
                     /locus_tag="ACF3MF_001106"
     CDS             27114..28784
                     /locus_tag="ACF3MF_001106"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HFE3927117.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            28931..29317
                     /locus_tag="ACF3MF_001107"
     CDS             28931..29317
                     /locus_tag="ACF3MF_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927118.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            29304..30002
                     /locus_tag="ACF3MF_001108"
     CDS             29304..30002
                     /locus_tag="ACF3MF_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HFE3927119.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            30007..30471
                     /gene="lspA"
                     /locus_tag="ACF3MF_001109"
     CDS             30007..30471
                     /gene="lspA"
                     /locus_tag="ACF3MF_001109"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HFE3927120.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            30468..31379
                     /locus_tag="ACF3MF_001110"
     CDS             30468..31379
                     /locus_tag="ACF3MF_001110"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFE3927121.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            31614..32153
                     /gene="pyrR"
                     /locus_tag="ACF3MF_001111"
     CDS             31614..32153
                     /gene="pyrR"
                     /locus_tag="ACF3MF_001111"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HFE3927122.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            32167..33450
                     /locus_tag="ACF3MF_001112"
     CDS             32167..33450
                     /locus_tag="ACF3MF_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HFE3927123.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            33463..34389
                     /locus_tag="ACF3MF_001113"
     CDS             33463..34389
                     /locus_tag="ACF3MF_001113"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HFE3927124.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            34408..35688
                     /locus_tag="ACF3MF_001114"
     CDS             34408..35688
                     /locus_tag="ACF3MF_001114"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HFE3927125.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            35693..36769
                     /locus_tag="ACF3MF_001115"
     CDS             35693..36769
                     /locus_tag="ACF3MF_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HFE3927126.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            36774..39959
                     /gene="carB"
                     /locus_tag="ACF3MF_001116"
     CDS             36774..39959
                     /gene="carB"
                     /locus_tag="ACF3MF_001116"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HFE3927127.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            40013..40789
                     /locus_tag="ACF3MF_001117"
     CDS             40013..40789
                     /locus_tag="ACF3MF_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HFE3927128.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            40786..41718
                     /locus_tag="ACF3MF_001118"
     CDS             40786..41718
                     /locus_tag="ACF3MF_001118"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HFE3927129.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            41715..42431
                     /gene="pyrF"
                     /locus_tag="ACF3MF_001119"
     CDS             41715..42431
                     /gene="pyrF"
                     /locus_tag="ACF3MF_001119"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HFE3927130.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            42438..43067
                     /gene="pyrE"
                     /locus_tag="ACF3MF_001120"
     CDS             42438..43067
                     /gene="pyrE"
                     /locus_tag="ACF3MF_001120"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HFE3927131.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            43055..43369
                     /locus_tag="ACF3MF_001121"
     CDS             43055..43369
                     /locus_tag="ACF3MF_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927132.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            43407..44048
                     /locus_tag="ACF3MF_001122"
     CDS             43407..44048
                     /locus_tag="ACF3MF_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbR-like 5'-deoxynucleotidase"
                     /protein_id="HFE3927133.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            44091..44783
                     /locus_tag="ACF3MF_001123"
     CDS             44091..44783
                     /locus_tag="ACF3MF_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HFE3927134.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            44780..45682
                     /locus_tag="ACF3MF_001124"
     CDS             44780..45682
                     /locus_tag="ACF3MF_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFE3927135.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
BASE COUNT        15014 a         8004 c         9886 g        12877 t
ORIGIN      
        1 ttttttcttg gtttcagatt gggttttcct acaaaatatt tttatctttg ttgaatagga
       61 aacaaaaaaa caatataatg aaagaaaaag aaggtgtaga aatggataaa agacaactgc
      121 taatagaaga atatctggat ttagctaatg agattattca tcgtaataaa ccagaaatgg
      181 aaaaagaatt tgcaggattt actctaaatg aactagaagt gattgaacat atcgggaaaa
      241 tccctgatcc taacgtgaca aaattagcga atgctagtta catgactaga ggagccatca
      301 gtaagctaac aaaaaaactg atagctagag ggatcataaa cacttatcaa agcgaagaga
      361 ataaaaaaga aatctatttt caattgacgc caatcggaca aaaaataagg aatagacacg
      421 agcaactcca tcaaaaatgg gtacagcgag atgctactgt atttgaaaat atgtcaaaag
      481 aagaatttga cacagtattt cgttttatcg gtcgatacag agaatttata cgaagtagca
      541 aatgaagcta ctatttttta ttgtagtgat aataggcaaa aatcataagc aaaaatccga
      601 ataccgtcgg aagaaatggt gctgcagcat aaagctgtcc tgcgattagc gggccgatga
      661 cgcgcgatag agattgtata ctttgggtac cgcccattac aagaccttgc tggttatctg
      721 agacagaatt ggatagttgg ccattgaata caggagtaaa aatagaatca ccgaaaccat
      781 aacagataat cccaaataaa aacaaaatcg gcagtagaag aattccagat aatgtgatga
      841 atagataggc gaggatttca ctgaacatcc ctattcttgt gatctgctgt tctgaaaatt
      901 ttttgagcaa tcgaggcata atgaacaatt gcgagacagt atccaagatt ccaatcaaag
      961 agaagcttaa accaaccaac ccagccttcc actgaaaggc gtcaatcgaa aattgagaaa
     1021 agatagattg aagagagcca gctgccaacc aaacagcaaa acctgctgtc aataaaggaa
     1081 taacggatga aatcttgaat aattgttgta attggtgaaa aggtcttaca tgggagaaac
     1141 ttaaatctac tgaacgtttt tttattggaa ggctttctag cataaatgtg tagccataaa
     1201 cggcatttaa gaaagtaaag agtgctccaa taaatatagg aacagaattc cccaactcag
     1261 ctaatagacc ccctataata ggacccagcg ttgttcctat accgactaaa gcacccatcc
     1321 atccaaaaac tttggttctt tcattaggtt ccgtgatgtc ggcaaagtaa gcatataagg
     1381 tggagatttc tcctgccgtc aatccttcaa tgatacgacc aaggaacaac atccatatcg
     1441 aatttcctaa accaaaaagc aaatatccga tacttgatcc taataaactg ataataagga
     1501 tcggatgacg cccaaaatga tcacttaagc taccgagaat gggggcagat aagaaggcag
     1561 ctagagcata aacagacatg agcaaagtga tatagaaagc ttgctgatgt atggagtgag
     1621 aataaggcag cgttaaaaac ggaagtacag gactgacgat agtaaatcct aatccagtga
     1681 ataagacaga gacgtatcca aaaactttag aatgtttatt tgtgaaactg tacatgtaaa
     1741 aactccttta tgcaataatg ttaacttgga aacaaaaata gtgtatagta attttgtttc
     1801 cttgtcaaca ttctaaggaa cagcgaaatc tacttaattt atttattccg aaaagtgaag
     1861 atacgcatca aaaacatgaa caaacaaaaa tcaagtagac gacattgtaa atctgaccga
     1921 tcagtgaagt aaatagaaaa gaaacctgtt cttgcttctc atgttttttt tacgtatact
     1981 gtgattgagc ggaggagaaa tcatgttgaa tttagaaaat tacttaagcg ctggacaaac
     2041 agtcatatct aatcttttac ttaaaaatta tcataggatc ggtctacaat ctgaagaatt
     2101 tttatttgtt ctacagttgc atatggcaca gcttgaagga gatactttcc ctgatttgca
     2161 gatgattgct atggatatgg gaatcaaaca agatcagatt tttcaaatac tggatcgtct
     2221 cgtaacaaat ggatttatca agatagaaac gacgattgtc aacggtaaaa aagcagatcg
     2281 atataatctt taccccatct atgatctatt aggtgagtat ttaaaaacac aagaaaaaaa
     2341 atacgaagaa aaaacacaag aaaaagaaat ccagtcagtg tatcaattat ttgaacaaga
     2401 atttggacgc ccgctttctt cgatcgagtt ccagcggatc ggacaatggc tagaagaaga
     2461 ccattatcag ccggaaattt tgaagctagc actgcgggaa gccgtattaa atcaggctta
     2521 tagttttaat tacgttgacc gcattttgct atcgtgggaa agaaaaaatc tacgtacaaa
     2581 acaacaagtg gaagaagacc aaaaacgaag aaaacagcag cttcttcaaa gagaagtaga
     2641 acagtcagct caacaagaag aattgccgaa agtctcactg aaaaattggt tggaggagta
     2701 gcggaatatg ttaagcaaac aaaaaacaat ggaagctcta gaaacgatgt atggaatgtt
     2761 tcccgaagca catggagaac tcaagcacaa taatccattt gagttattga ttgcagtgat
     2821 cttaagtgcc caggcgacag atgtatcagt gaataaagca acgccagatt tgtttgcctc
     2881 ttttccgaca cccgatgcgt tagcagaagc ttcaatcgat gaaatcattc ttaaaataaa
     2941 aacgattggt ttgtatcgaa ataaagcaaa aaacatcaaa gcgtgtgcac agcagctgat
     3001 tgaacgtttc gatgggcaag tgccaacgtc aagagaagaa ttgatgtctc ttcctggtgt
     3061 aggcagaaag acagcaaatg tcgtattggg ggatgcattc gggataccag caatcgcagt
     3121 agatacccac gtggaacgtg tctcaaaacg cctgaggatc tgcaaactag atgctacggt
     3181 catggaagta gaagaaacac tgatgcggaa agtaccacaa gaattatggg taaagacaca
     3241 tcatacactg attttttttg gtagatatca ttgcacggca agaaatccca agtgcgaggt
     3301 atgtcctttg ctatcaatat gtcaagatgg gaaaaatcgg atgcgtctaa aagaaaaggc
     3361 gctaaaaaag aaaccacgcc tgtagacgtg gtttctttaa ttgcaaataa atgtatgaat
     3421 tatcttgtta ttatggagaa aagctgtttc gtttatcttt tttgcatgaa aaagtaaatg
     3481 tacatactca gtagctagga tggtaactta ttacaattta ttgcgataaa aataaaagtt
     3541 gttattttta ttgggaaaat acccgatgta gaaaataatg ccttccaata tacctataaa
     3601 ataagtccag tattccaaag gattatataa ataagtgacg tatctatcta aaggtgtaat
     3661 aaaaatgata agtgataata aaaaaatacc atttataact aaacataaac taatggattt
     3721 gggcggtttc aggctcatca gaaaaatata gattctggtg aacaacaacc ataaaaaagt
     3781 gagaatcatt gcatgagagc ttctttccat aaattttcct ttaagagtag tgcttaaaag
     3841 tacagaaaaa ataataaatg caaggatagg agcaattaaa gtaaatttat ttaataataa
     3901 acaaaatttt tcagcttttt tattcttgga ataacgaggt attgttttcg ataaaaaaag
     3961 atggtgcaga caaattatga taattaagca tactatcaga taactcaaaa tgaagccttc
     4021 tttcaaaaaa ttattcaaaa ccatatattg tattttttat ttgataataa caatgggatt
     4081 attaagaagt ggcactaaat aaaagactag tgtgtattta gccgatttaa ttataaacaa
     4141 gtaaatggat aaagtatatg taatgataaa agaaaaatgg attttctaat ttttaagcta
     4201 aatgttagat cacacatgta tatgctggat agtcttataa aaaatcatgt aatacagctt
     4261 ggtacatgat ttttatttgt agctgttttt tacatagaca caaaaaagaa accacgcttg
     4321 tagacgtggt ttctttttta ctatctgttt ccagaagctg aggtgctgct ggatggtgta
     4381 tggtcatttg cagcatccgc tccgctagtt gctggctcac tggaagaagc aggaggagca
     4441 gatgaagacg gtgtcgagct ttcttcggat gaagaagaag gaaccgttgt tgaagacgct
     4501 ggctcgcttg tttctgctgt cgtgctttct tttgaggact cagcagttga ttcgctttga
     4561 ctagtagagc tagagctttg agtcgttgtc tctgttgttg agcttccagg agtctggaca
     4621 tagctggaag atggaatagt tgttgatggt gtaattgcat tcgatctagc tgtatattga
     4681 tctttgtagt acagttcacc gcccacacga attaatccgc ttggcatctc ccagtctgta
     4741 tttgtcacgt tagctgaaac atactgcata agctcgcgat aaacatcaga ggctacgtgt
     4801 gacgattctg aagtgacagg tgtcattttt ttattgtaac ctgtccacac ggaaatcgaa
     4861 taatttggcg tatagcccgc aaataggata tctggataca ccccagaaga aataccaagt
     4921 tttgcatact cgtcatctgt gtaattggat gttccggtct taccggcttg atataaccca
     4981 gcgatttgcg cattcgtacc agttccttca gtgatcgtat cttttaaaat gtctgtgatc
     5041 atataagctg tttctggaga catggctgtt tttccatctg gctcataagt ttcttctgtt
     5101 ccgtcttgga agacgatttt attaacatat tgaggtttgt aataagtccc tccattggcg
     5161 aaagccgcat aggctgctgc catttttaag gaagaagctc cgtattttgt cccatcttgt
     5221 tcttccgtat tactagagat cgcattcgat tgatggatcg tactgtattc gatcccaaga
     5281 ttttttaaga aagaagccac tttatctgaa ccgacttcat tgaataattt gactgctgga
     5341 acattacggg ataagtaaag tgcttggcgt aaagtaatgg tgcccatata ttgattatcc
     5401 cagtttccta caggagtcga agtcccttca tagttatacg gtgcgtcagt aatagttttt
     5461 ccagtagaat atttcaaata ttcaaaagct ggtccgtaat ctgtgacagg tttcatcgta
     5521 gaaccaaaat cacgggaagt attcactgct aagttgttgc ctaaagttac gtcttctgcg
     5581 atgtgacgtc cgccaatctg ggcttttact ttcccggtat tggtgtcgat aagggtggag
     5641 gcaacttgca tctcgtcgtc tgggtaagag acatactgat ccgtgttgac gatatcatat
     5701 agtttctttt gggcgtccag atccaaattc gtataaatct ctaaaccgtc tgtgtagaca
     5761 ttcttatctg ttttttcttg tacttcattg atgacttctt tgacataatt atcgacgatc
     5821 ttagtattgt catcggattg agttagttct tgcagaccat ccgttaccgg tacattaaca
     5881 gcttgatcat attctgtttg agagattttt tcgttttgaa gcatcgtata caaaacagta
     5941 tctcgtcttt tcttcgcctg atctggataa acataaggat cataggcgga aggggcttga
     6001 ggcatcccag caagcaatgc tgtttgcggt aaagaaagtt ctgataattt cttaccaaag
     6061 tacatctcag aagctgtctc catcccgtac aagccgtttg acatatacac tttatttacg
     6121 tagtaggtca agatctcttg tttcgatttt ttttgttcca atcttacagc catccacgct
     6181 tcttgggcct tgcgtttcag agtctgatcc tcggcactgg tggagaagaa ggaaagtttg
     6241 atcaattgct gtgtcaaagt acttccgcct tgcagtccgc cagaggtaaa gttagagagg
     6301 gcagaaccga tgatccgaat agggtcaacc ccgatgtgtt tataaaaacg gcgatcttct
     6361 accgacacga tcgcatcttc taatgttttc ggtaattcat tcgcagaaat tttttcacgc
     6421 ttttctgcgc ctaaatcttc gaatagttcg ccatcttgtg tatatagttt ggaagatacg
     6481 gtagcgtcta attttttatc cgtcaattcg ggcgcatctt ttgcgtaata ccagaaaagt
     6541 cctacacctg ctaaaaagag gatacagaaa aatgagagta ttcctaaaag gatcttgata
     6601 aataatcctt ttttatgtgt tccagaggac tttccagaac ctttgccaga attcttcttc
     6661 acactctttt taggagtagg ctgtttctgt cgtctagagc ttctagtttg ttcatttgcc
     6721 attcttgctt tctccttcaa tagataatgt tgataaatag aagtcaaccg cgtccaaata
     6781 aggaatccgc ggagaaatac cagttttgat ctctattcct agttcttcga tcaaagataa
     6841 aggtagtgat ttgcgtcctt tttccttttg ggcgtcccag taagcaatca aatgaacact
     6901 attcaaataa aaacagcgct tcaaagacga aaaccataac aagacaaagc agaccccatt
     6961 ttgttcgagg catgctttca tatgttcgat ttgatgggca tggaagtttt taaagggaaa
     7021 agatgttttg ttcttggttt cttttgcttc aaagtccaag taaaagcctc gatagacgcc
     7081 attatagtct gtagttgagg cttgggtaaa gtaggcttcc ttgatcacag cagcacttct
     7141 cttaggatag tctactttca cgatttggat aggggtaggc tttttatgga taaccgccaa
     7201 cccgcgggaa agataatatt tattactttc attgattgct tcttcaaagc gcatcccccg
     7261 attgccgaat tcagtgatct gatttctttt ttcttgaatt ttttcgacgg gagaggcatt
     7321 cttataataa ggttggccat ttggatagcg caataccatc tttaatcaca ctcctaggcc
     7381 acattatagc aaaaaagcgg atagaaagaa aaggaatctg agatggataa gtcaaaagta
     7441 atctatgtgt ctgggtatcg aagtttcgaa ctcggtgttt ttaaagaaaa tgatcctaaa
     7501 atccaagttg ttaaaaatgt tttaaaaaaa gaactccatc agttagcaga agaagggctg
     7561 gaatgggtac ttgtcagtgg gaatttgggc gtcgaactat gggctgtgca aatagtagcg
     7621 gaattgaaag aagaatatcc ggaactatct cttggtattt tgtatccttt ttctgatttt
     7681 ggtaataact ggaatgaagg gaaccaagaa aaaaaacaat tagcagaaca attagcagat
     7741 tatgtcgaag ctgttagcca tcaaccctac caatcaccta gtcagctaaa gaatcacact
     7801 cgttttatac ttgagcatac agtgggctgt ctgctgatct atgatgaaga attccctgga
     7861 aaaacgaagt atttttttga agatgcacag aattaccaag cagatcatcc ctacgaaatt
     7921 cggctgatca gtatggacga tcttcaaaat tttagtgaat aatcgatatt gtgtttgatt
     7981 tatcaacttt tttcctatac aatgaaaaag gtagaaatgt tattacgtaa atgaaaacta
     8041 gaggtgtaaa tatggcgaat ttggtttata gtcctaaaga cattttacaa caagaattca
     8101 aaacaaaaat gcgcggctat gatcccgttg aagttgatga attcttagac aatatcatca
     8161 aagattatga aacttacagc aaagaactcc ttgctttaca agaagaaaac gatcgattga
     8221 gtgcaaaagt agctcaatta tctaaaactc aaggagcagc tcaaacacgc gtgcaacaaa
     8281 cagaggcacc aaagagcgca gcagtgacca attttgatat cttaaaacgc ttgtcaaatc
     8341 ttgaacgtga agtatttggt aaaaagcttg atcaacaagc aagtgcagtc aaaccagcac
     8401 aacctaatcc aaataactac acaaatgcag acacaagctt agatgataat gaaaaaacac
     8461 gtcaatttta atttttgatt aatgaatttg cggttttcgg gtaatcgcgg tctgacttga
     8521 tcaggctgag gaaagtccat gctcgcacag gctgtgatgc ctgtagtgtt cgtgcttagc
     8581 gaaaccataa gctaaggtac tctttggagt aacggcagga aaacaagcta aggcttcggc
     8641 tatgcttaag tatccttgaa agtgccacag tgacgaagcg gctggggaaa cccatccggt
     8701 ggaacgcggt aaacccctcg agcgagcaac ccaaacaatg gtaggggcgc tttttgtctg
     8761 gaagaagaac aggacaaaaa ggcagtataa ctgcagatag atggttaccg ctttgttttt
     8821 tctccctgga aaagcaaagt acagaacatg gcttatagaa aaccgcaaac atcagggaat
     8881 taggtcgtga caaaagtaat gcgttataag aaacaagaaa aacatttgaa agctattttt
     8941 caatacttca gatgaatcgt tcttattaca aaacaaactt ttgtatcacc ggttattcgg
     9001 aatttgagta aaagtgtggg gtaggactga tgtcccacct ccttttttta taaataagga
     9061 gattgtgtat ggaaaaaaac aggaagttca acctcgtcgc aactgcggca agcgggctag
     9121 aagcactggt tggtaaagaa ttaagagatc ttggaatcga atgccaagtt gagaacggac
     9181 gtgcacgttt tgaaggaaca atggaaacga tcgctacagc taatttatgg ttacgtacag
     9241 cagatcgagt aaaaatcgtg gttggggaat tcgatgcgta tacgtttgat gaattgtttg
     9301 aaaacgtaaa agcattgcct tgggaagatt ttcttccact agatgcagct tttcctgtag
     9361 ctggaaaatc gatcaagtcg aaactatata gcacacctga ttgccaagcg atcacaaaaa
     9421 aagcaatcgt tgaacgtctc cgtacctatt atcaccgtcc agcttctgta ccactgacgg
     9481 aaactggcgc acattttcag ttggaagtag ctttgctgaa agaccatgtg atggtaactc
     9541 tggatacgac aggaccaagt ttattcaaac gtggttatcg cttagaaaaa ggtggagcac
     9601 cattgaaaga aaacatggca gcagcactta ttatgttgac aaattggcga aaagaccgtc
     9661 cattttatga tcctgtatgt ggttcaggta cgctttgtat tgaagcagcc ttaataggcc
     9721 ataatatcgc accaggattc aatcgtgagt ttgcttgcga atcttgggat tggttcagtc
     9781 aagaaatcat ggaaaatgtt cgatcagcag ccgaagaaaa agcagattat gatattgaat
     9841 tagatattac tggttcagat atcaatggac ggatgattga aattgccaaa gccaatgcag
     9901 aagaaatcgg attaggctct tcgattacct ttaagcaaca agcagtcaaa gacttcaaaa
     9961 cggataaaga atacggggtc atcgtggcta atccgcctta cggagaacgt ctaggagaag
    10021 aagaaactgt tcggaaatta tataaagaaa tgggcgatgt attccgtcca ttaaaaacat
    10081 ggagtaaata tatcttgact agcgacttag cgtttgagga attttacgga caaaaagcaa
    10141 ccaaaaaaag aaaattgtac aatggtgcat tgcgtacgga tctattccag tattggggaa
    10201 ctcgtccgcc tagaaaaaaa gagaaagacg aataatctta ctaattgatt cattcaattg
    10261 gatgtttgga ggaataggga atgaaagaaa aagagttttt acaagaagta aaagaaatca
    10321 atcttctaca acaagcttta ggaatcctcg attgggatac acaaacaggt atgcctgaaa
    10381 aagctagtgc ataccgaagt gaagtagaca gctatcttta cagcatttat ttttcaaaaa
    10441 aaatcggtcc aaaaatcaaa gaagccattc gctatttttc tgaacatccg gaagaattgt
    10501 cggaagttgg aactgccgtt tttgccaaag taaaagaaga gtatgatttg gaacatcgcg
    10561 taccggaaga tcttatgaga aaatatacag ctgccgtttc ttcagcacac ggacaatggc
    10621 aaaaagctag agaaacacaa caattttctg attttcaaca cgcattgaat caaaatattg
    10681 aattaacaaa acagttgata ccttactgga gaaaagatga aaagacgaat tatgatgttt
    10741 tgctgaatca atacgaaccc gggatgactg tcgaaatcct tgataaggta tttgatcagc
    10801 ttaaagaagg aattctttcg atccgccgta cgctccaaga aaaagggact gaacctgaaa
    10861 cagacttttt aaatcggaga atgacgaaaa aacaacagaa gagatttgta gtgaaagtaa
    10921 tcgaacaact tggttatgat tttagtcgtg gtcgtttaga tgacactgtc cacccattta
    10981 tgactggaat taatccgaat gatgcacgaa tcacgacacg atggaacgaa acagatttca
    11041 aaatggctgt ttttggagtg atccacgagg ctggtcatgg tatgtatgaa caagacatcg
    11101 atgataaata tgcgtataca ccggtttatg aaggtacatc aatgggtatc catgaatcac
    11161 aatcgttgtt taacgagatc attattggaa gtagtcgcag cttctggaaa aagcaatatc
    11221 ctttctttca agaatgtgca gaaggaacat tcgatgatat tccttttgac aaattttatc
    11281 gttcattgaa ccatacaaaa tcaagtttgg ttcgtatcga ggcagacagt ttgacttacc
    11341 ctctccatat catcattcgt tatgaaatcg aaaaaatgat tttcaatgaa ggggtagatg
    11401 ttgctgaact acctgaaata tggaatcaaa aatatgaaga gtatctggga atacgaccaa
    11461 caaatgatgt ggaaggcatc ctacaagacg ttcattggtc aggtgcaagc tttggttatt
    11521 ttccctctta tgcattaggg tacatgtatg cggcacaatt acttcattct ttgcagcaag
    11581 aaatagatgt ggaaaatgtt ctagcgtcag acgattattc tccaatcaaa aactggatgt
    11641 cagagcatat ccatcaatat ggtgcatcta gaaaaccaaa tcaattaatc atggatgcaa
    11701 cacatgaacc gcttaatccg caatacctga tcgactatat gaaagacctg tattttaatg
    11761 tatatcaggt aaaataaaat acaatttaca aagatagctg aaattcatct aatctataga
    11821 tgttttcagc tatttactta agaaagaagt ggaacgaatg gataaattac aagtgatcgc
    11881 tgattatagt atggaccaat tagcgcatga tcaaacagga catgggagcg atcataccaa
    11941 aagagttgtc aagttagctg aaaaaatttt ggagacggaa ccgcaggcag accgctttgt
    12001 gacgcttgca gcagcttacc tacatgatac gattgatgat aaagtcgtta aaaatgagaa
    12061 cgaggcaaag caacagcttc gtgtattcct tcgctctttg ccaatagtag aggaacagat
    12121 ctcgatgatt ttttccatta tcgaaaatat gtccttttct aaaaatctct ctgaagcggc
    12181 cgaactatct ctggaaggta agatcgttca agacgctgat cgtatcgaag cattaggagc
    12241 aatcggcatt ttgcgtactg cttatttcgg cggtggacat gggcacccga tttttgatcc
    12301 tgaactgtat ccgcaaacat tcaaggacaa agaaaattac cgaaaaggca cgacagtgat
    12361 caatcatttt tatgaaaaac tgttcttgct gtctgataaa atgaatactg attacggata
    12421 tgaagaagcc aaacgaagag aaaccttcat gcgtgaattc ttagaagaat tttttctgga
    12481 atggtctatt gacgatgaaa attttactcc agacaattgg atcaaaaata acaaaaaatg
    12541 atggaggttg tgacagaagt ggtcagctcc aagatatttc ggatcatttt ccgtaaaagt
    12601 tacttctgga acactgttta ccaagaggtc gtgagcctgc cgttcagctc cgagtcacaa
    12661 ggaacaattt caaaaaatag cttctcgtgt ttgatgaata ttgtaacttg tgattcggaa
    12721 ttggcaggag aacaccgttt attcggaaga ataggactgt gacaagactt ttgtcacagt
    12781 ccttttttcg aattcaacaa gtaaaacttt taagaaatat tcagagagta aaattaaaaa
    12841 ttgctgataa acgaagatgg aaattttatg tatttttatt ggtctatgca ataaataaat
    12901 taaatattca gaatacaatt gattttaacg aaagggcttc tatcaatggt tgtgttgtat
    12961 ttatctgccc aggtagagta aaatagatca ttatctaaaa ggtaattgtt catactatat
    13021 aagtcatttg aaagtaaaaa gatactgtaa ataaaaaatg tggttaaata attctcataa
    13081 tcagtgtaag cgttatcaaa aatatagcat acttgctttg tagatgaatg acacgatata
    13141 tgtttggtat gttctgcaag acagatgaat atggaggtgg agacaatgtc ttccaaagaa
    13201 ctaacaatgt atttagagaa agaattggat caactgaaag aaaaggggtt atacaatacg
    13261 atcgacatac tagaaagtga aaatggtgct tgtatcatcg tagacggaaa aaagatgatc
    13321 aatctagcat ccaacaatta tcttggattt gccaatcgcg aagaattgaa aaaagcatgt
    13381 attgaagcaa ccgaaactta tggtgtagga gcaggagcag tccgaacgat caatggttcg
    13441 ctgaaaatcc atcagcaatt agaagaaaaa atcgcagaat tcaaagggac agaagcagca
    13501 atcgcctttc aatctggatt caactgcaat atgggcgcta tctctgcagt aatgacaaaa
    13561 gaagatgcta tcttatcgga tgaattaaac catgcatcta ttattgacgg ttgccgctta
    13621 tccggagcaa aaatcatccg aattaaacat caagatatga aagaccttga gaaaaaagca
    13681 aaggaagcga tagaaagtaa gaaatataaa aaaatcatgt atatcacaga tggtgttttc
    13741 tccatggatg gagacattgc acgattgccg gaaattattc cgattgttga aaaatatgga
    13801 ctgatcacct acgtcgatga tgcgcacggc tcaggcgtaa ctggaaaagg tgcaggaacc
    13861 gtcaagcatt ttggattaag cgacaaaatc gatatgcaaa tgggcacgtt atcgaaagct
    13921 ataggtgttg ttgggggtta tgtagctgga tcgaaaacac taatcgactg gttgaaagct
    13981 agaagtcggc cattcctatt ttctacttcg ctaactccag gtgcagctgc agctgcattg
    14041 gcttcgatta ctttgatgca agaacatccg gaacttgtcg aaaaagtttg ggaaaatgct
    14101 aattatttta aagaagaatt gaaaaaagta ggctataaca tcggtatgtc tgaaacacct
    14161 attactccag tcattttggg agacgaaaaa gtgactcaga ctttctctaa gaagctgatc
    14221 gaacatggga tttatgctaa accaatcgtt tatccaactg tgcctcttgg gacaggcagg
    14281 atcagaaata tgccgactgc ggaacatacg agggaaatgc ttgatgaagc agtagcagtt
    14341 tatcaaaaaa taggaaaaga aatggaaatt atttaactaa atttagtttt ttcgtctatt
    14401 taaaattaga gaacatgttc acgcatatat tgttaatcat ctgaagatag tagtaaaaaa
    14461 gatcagggag gatcatcatg aaaaaagtat tggtgacagg atgtttagga caaattggtt
    14521 cagagttgat cacacggcta cgtcaagaac taggcagtga aaatgtcatt gcgacagata
    14581 tacgcatgcc tgaagtcatt gagaaaaacg atatctttga gatcctagat gtaatggatt
    14641 acgaaaaaat gcgcagcata gcagaacaat atcaagtgga cacattgatt catttggctg
    14701 ctcttttgtc agctgttgca gaagcaaaac cacaattagc ctggaatttg aacgtgactg
    14761 ggctggtcaa tgcattggaa gtcgctagag aattccagct gaaatttttt acgccaagtt
    14821 caatcggcgc gtttggtcca aatactccaa aagatcatac cccacaagat actcttcagc
    14881 gtcctacaac catgtatggg gtaacgaagg tagctggaga actactatgt gattattatt
    14941 atgtgaaata tggcgtagat actcgtggtg tccgtttccc tggattgatt tcttatgcaa
    15001 ccttgccagg aggcggtacg acagactacg cagtcgatat ttattattca gcaatcaaag
    15061 aaggaaagta cactagtttc attgatcaag gtacatcaat ggatatgatg tatatgccag
    15121 atgcgatcga tgccattata aaactcatga atgcagatcc tgatcgattg gttcatcgaa
    15181 atgccttcaa tatatcggcg atgtcttttg acccggaaga gatcaaagca tctattcaaa
    15241 aaatcatacc agattttgaa atggattatg atgtggatcc tgtacgtcag tcaatagcag
    15301 aatcttggcc aaattcacta gatgtttctt gtgcgcaaga ggaatggggc ttttcgccga
    15361 aatacgactt agatgtgatg acaaaggata tgttggaaaa actgaaagaa aaattggtag
    15421 agacggtata aaacaagaac cacatccaaa aagtttttta tacttttggg attggctatg
    15481 gtatgaaagg ggacaaggga tggaagaata tcaagccacg ccagtaaaag aagtaaaaat
    15541 agaaaatgaa ttaaaacgta cgatgggatt ttttactgct ttatcgactg ttatgggcac
    15601 agtgatcggt gcaggggtat tttttaaagc cgcaagcgta gcagaagtta caggatccgc
    15661 cagtttgcat atgttttctt ggtttctcgg tggtatgatt tctgtctgtg caggactaac
    15721 aggagctgaa ctggcagctg ctattccaga aacaggaggg atgattaaat atatcgaacg
    15781 gatttacgga aatacagcag cttttttatt gggctgggcg caagtcgtga tttattttcc
    15841 agcaaatgta gcagccttgt cgatcatttt cggtacacag ttcgtcaatc tatttggtct
    15901 ttcccagtca atgattgttc ccgtagctgt tacagctgct gtatcgatcc tgttgatcaa
    15961 ttttttaggt tctaaagctg gaggggcttt tcagtcgatt acgcttgtct gcaagcttat
    16021 tcctttgttt gtgatcgtca ttttcggttt gttccgacaa gaaggagtag acttccaact
    16081 gtttccgatc caagcaggag aaaatctttc atttttctca gccttgggag cgggcttgct
    16141 agcaacgatg ttcgcatacg acggttggat acacgtagga aatatttcgg gagaattgaa
    16201 aaagccggcg aaagatttgc caaaagcaat ttctttagga atcatcggaa tcatgatcgt
    16261 ttatttatta gtaaatgcgg tgttcttaag aaccgcatct atcgacggag tcgcaggaaa
    16321 cagcaatgcg gcaagtgacg ttgcaaaaat gatttttggc ggcttcggtg gaagactggt
    16381 cacagttggt atcttgattt ctgtttatgg aaccatcaat ggctataccc ttactggaat
    16441 gcgtctccct tatgttattg caaaagaaaa caacctgcct tttagcaagc tctttgctaa
    16501 acttcatgat aaaactaaag ttcctgtagc cgcaggtatc ttagagctag tcatcgctat
    16561 tggcatgatg atgatcggtg gttttgatac actaacggat atgctgatct ttgtcatttg
    16621 gattttttat acgatggtct ttgttggtgt cattcttctt cgtaaaaaag aacctgattt
    16681 gtttcgacca tacaaagttc caatgtatcc gtttattcca ctagtagcaa tcattggagg
    16741 gacttttatc gtatcaagca cgcttatcac tcagaccttt ttagcttcga tggggatagt
    16801 attgacactt gctggtatcc cgatttatct ctatttaaaa cgtagatagc taaaacattc
    16861 gaattttatt agaactgcac ttctctgcca aacaaaatat tttatttaaa tgaggagtac
    16921 gtggaagaaa tgtcaaaagt actcgttaat tttgatcacg taaatgtcgt tttgtctacg
    16981 atgaaatagc aaagtaaaag acagaaatcg ggctcaaccg atttctgtct tttactttga
    17041 tttgcgtaac tgaactattc ggcgtacgcc gcgataaata tttaataaaa ccaagcaacc
    17101 agaaatgaaa atgggaagcc aaatcagata gacagggtag ccaagcactt tagacaaagc
    17161 atgtggagtc attttatcca tttcaagaag tgcttgctgc caagtctgaa gattgaagac
    17221 tagcatgaaa cccgaaataa tcaggagaat aaatcctaaa taatgaattg tagttctttt
    17281 tcttacataa gcgatcgtag cataaaggaa cagtaaaaaa ataggtacgc caaaaacaaa
    17341 gtacatattc agcatctcga cacccccttt gtgtttatct tactttactt tgaaagaaat
    17401 gagaaataat agcctcgtta cttgcttgaa acagcaaagg actgctaaga taagagagat
    17461 acaaagaatc aaggaggagt catatggcaa gttatatcga accgattcgt tttgcgctga
    17521 ttgtttttcc atttttagcc ttagcgatct catctgtttt ttttatttat gaatatcgaa
    17581 agtatggaac atttctagta acaagggcag ttattttgta ttctttcgtt ttttatttat
    17641 tgtgtgcgta ttttttggtg atcttaccac ttccggcaaa ggagacggtt gcccaaatga
    17701 cagggccaaa gatggagctg catttatttg cttcatggca acatttcaga gacaacacgg
    17761 tattggtctt gtctgaacct agtacctacc tgccggcaat gaagcagagt gtatttttgg
    17821 aaccagcttt taatgtttta ttactcatac catttggcat ttatttaaga tattatttcc
    17881 ggctttcttt tatgaaaacg atgattgcta gtttctgcct ttctctattt tttgaattga
    17941 cgcagctaag tggactttat tttatctacc caagaccata ccgcttattt gatgtgaatg
    18001 atttagtgac aaatacattg ggtggaatca ttggttttgt cgttacgccg ttatttacat
    18061 ttatgcttcc tacaagaaga cgaatggatg aactttctta tgaaaaagga aagactgtct
    18121 cattgactcg acgcttggtc gcttatttga tcgactggac atttttatct cttattaatt
    18181 tggtagcggc gattttcttt aaaattgcgt tcgattcagg ggcagttact tctcatatct
    18241 ggtggctttt attagaagta ggggtatact ttatgattgt accgtttata accaatggat
    18301 ggacacttgg caaaaaaatt gtgcgtatcc gtttggtgga agaagaccgc gaacgaattt
    18361 ctttaaaagc attgatgatc cgctacgggt atctgtactt tcttttttat ggtttaagct
    18421 ggttggggca gttgcttcag caaatcatga attcgacaac gaatacggtg ttgcagatga
    18481 gtgcagtatt catttctctc ggtgtcttgt tactacaagg tatttttatt ttaaatatct
    18541 tgctatcatt tttgagaaaa aaacggattc tgttttatga aaaagctagt cacacatata
    18601 ctgttagcac gattggccaa acaaaggatg atgattctcg aaattagctg agcaaaaacg
    18661 ctttgtctgt gttataatgc caaagtcgtg ataatttaaa gagaagaggt gcacgaatga
    18721 ataattttga tatattccgc ttcaaaccgt ttatcaatga agcgttaacc gcaaagggct
    18781 tcaaacagcc cacagaggtc caggaacgtt tgattccttt aattgcaaaa ggaaaaaata
    18841 tcattgggca atctcaaact ggtacaggaa aaacacatac gtttttgttg cctttgtttg
    18901 aaaaaatcaa tgcagaaaaa gaggaagtac aagttgttat tacagctcca agtagggaac
    18961 tagctgcaca gatctatgaa gcagctacac aaatcgctaa attttctaca ccggagatcc
    19021 gtgtctcgaa ttttgtcggc ggtacagaca aacagcgtca attaaatcgt ctgcatcacc
    19081 aacagccaca ggttgtagta ggcacgcctg gtagaatatt agacatgatg aatgaacaag
    19141 cgctgaagat tcacaccgca tttgcatttg ttgtcgatga agcggatatg acattggata
    19201 tgggtttttt aaatgaagta gaccaaattg caagtcgatt accagaaaag ctgcagtttt
    19261 tagttttttc tgccactatt ccagaaaaac ttcgtccatt cttacgaaaa tacatggaaa
    19321 atccaatcat tgaagaaatc aaaccaaaag cagttatttc tgaagacatt gaaaattggc
    19381 tgatttcaac aaaaggtaaa gatgagaatc aaatgattta tcaactgctg acaattggtc
    19441 atccttattt agcaatcgta tttgccaata caaaacagca tgtggatgaa attgccgatt
    19501 acttgaaaaa ccaaggcttg aaagtagcaa agattcatgg agacatcacc ccaagagaga
    19561 gaaaacgagt gatgcgacaa gtacagaatc tggagtatca atatgttgta gcgactgatt
    19621 tagctgctag agggatcgat atcgaaggtg tctctcatgt tattaatgca gaaattccag
    19681 aagatctaga cttctttatc catcgtgtcg gacgtactgg acgtaatggc ttaaaaggaa
    19741 cggccattac gttatattcg ccaaatgatg agcaagccat tgatgcgata gaaaaattgg
    19801 gcgtctcatt tgaaccaaaa gaaatcaaaa acggggaaat cgtcaaaaca tacgatcgta
    19861 atagacgtgc caaacgagaa aaatcaaaag atgtattaga tcccacgctg attggtcttg
    19921 tgaagaagaa aaagaaaaag atcaagcctg gttataagaa aaaaatcgat tgggcaattg
    19981 cagaaaaaaa taaaaaagaa cgcaaaatcg aacgcagaca gcaaagccgt actgctcgta
    20041 aaaataagaa aaattcacat aaataaaaaa caagaggttg tgacaaaagg cgtgtcacaa
    20101 tctcttgttt ttaagctaga ctttttttca ttccgataca aagtacttca tcttcaataa
    20161 aaggttctgt gcaagtatga tacccttgtt tttcataaaa atctacagcc gtcatttcag
    20221 ctactacata actagtctga caaccttctg aaaccgcccg tttttcagca gcttcaagca
    20281 actgaccgcc taaccctttt cctcggtatt cttttgctac gcaaaatcgt tccggcttga
    20341 agcaagtagg tgttttcttt tcataacgca aagtagctac tggtcttttt tgatcaagaa
    20401 atagataata ggtttgttgc gggatatctt ttccgtcgaa ttctagttct gcaggaatcc
    20461 cttgttctaa tacaaaaact tgatatctca aaaagcagct agctgcgcgt atccattcat
    20521 ccgctccaac tatttttttc atcatattcc tccttgtcat gaatagcaga gatgtattga
    20581 ttcctttatt cttatcgtac caaaaatcgt ggagtatgac caaaaggaaa tgaaaataaa
    20641 aattgagata ttgacagtga tcaatagaat gcgtatacta attaagtacg aaaaggatat
    20701 gatttgtttt ttaagactca cagaaaattc tttcttggct gaaaaaagaa tagtcactaa
    20761 tcaaattgct ccctttttct attttggtag aaataccgac gcagctcagc gttatcgagt
    20821 ttaagaggta atgattacac atcattgcaa tcaaggtggt accgcgagtt ttcgtccttg
    20881 gctgtgatgg tgtttttttg tatttaattt atagaaagca ggtaatgaca tgaaacaatt
    20941 aagtagtgca caagttcgac aaatgtttct tgatttcttc caatctaaag gacatacgat
    21001 tgaacctagt gcgtctttga tccccgtgaa cgatccaacc ttattgtgga tcaactctgg
    21061 tgttgcaaca ttgaaaaaat attttgatgg ttcagttgtg ccagaaaatc caagaatcac
    21121 aaatgcccaa aaatctattc gaacaaatga tatcgaaaat gtcggtaaaa cagcacggca
    21181 ccatacgatg tttgagatgc tgggtaattt ttcgattggt gactatttca aaaatgaagc
    21241 catccactgg gcatgggaat ttttgactga tccaaaatgg atggcattcg atccagaaaa
    21301 actttatgta acagtttatc caaaagatac agaagcaaaa cgcatctggc atgaagaagt
    21361 tggcctgcca ctagatcaca ttattgatgt agaagacaac ttctgggata tcggtgcagg
    21421 cccatgtggt ccggatacgg aaattttcta tgaccgtgga gaagcttata acgatttagc
    21481 agaagacgat cctgaaaact atccaggagg agaaaatgaa cgttatttag aaatctggaa
    21541 cttagtattt tcagaattca accataagcc tgataacaca tttgaaccac ttcctcataa
    21601 aaacattgat acggggatgg gattggaacg catggtctca atcgttcaag atgcgtcaac
    21661 gaactttgag acagacttgt ttatgcctat tatccacgcc gtagaaaagc taagcaaaca
    21721 agtaaaatat ggtgaaaacc cagtaacaga tatttcttac aaagtaatcg cagatcatat
    21781 tcgcgccctt tcatttgcta ttggcgacgg tgcattgcca tcgaatgaag ggagagggta
    21841 tgtcttacgc cgtttgcttc gtcgtgctgt catgcatggg aaaaaattag gtattgaaca
    21901 agcattctta tatcgtttag tccctgttgt tggggaaatc atggtaagtt attatcctga
    21961 agtacttcaa caaaaagaat ttattgaaaa agttatccgt acagaagaag aacgtttcaa
    22021 tgaaacaatc aatgaaggtt tggaaatctt aaatcaagtg atccaagaag taaaaaacga
    22081 aaacgggacg actctagcag gaaaagacat cttcaaacta tacgacacat atggcttccc
    22141 ggtagaatta acggaagagg tggcagaaga tgaaggactg aaagttgatc atgctggttt
    22201 tgaaaaagaa atggatgcac aacgcgaacg tgctcgctct gcccgcagta ctgaaaaatc
    22261 aatgggggta caatctgctt tattgacaga tatcaaagta gaaagtaaat tcattggata
    22321 cacagaacaa gaatcagata gtcaattatt ggtcatcgtt aaaggtgagt ctcttttgaa
    22381 tgaagtcgca gaaggtgaag ctcaaatgat ctttgatcaa acacctttct atgcagaaat
    22441 gggtgggcaa gtagcggatc aaggatggat catgaatgaa gtaggcgaaa tcgtagcagt
    22501 tgttacagat gttcaaaaag cgcctaatgg tcaatttatg cacaccgtag aagtaaaagc
    22561 accaatgagt gaaggacaaa cctatcatct attgatcgat caatcgatgc gcaatcggat
    22621 catcaaaaac catacagcaa cccatctact gcacaaggca ttgaaagaag tacttggcga
    22681 gcatgcaaat caagctggtt ctttagtcgc tcctggacat ttacgattcg actttaccca
    22741 ctttggtcaa atcacttcag atgaattagc tgaaatggaa agaatcgtca acgaaaaaat
    22801 ctgggaagct atcccagttg aaacaattga aacagatatc gatacagcca aaaacatggg
    22861 tgcaatggct ttgtttggtg aaaaatacgg acatgacgtt cgagtagtaa atattggcgg
    22921 ctggtcaatc gaactgtgcg gaggcacaca tgtagcaaat acagaaaaca tcggaatctt
    22981 caaaatcgtt tctgaatcag gaattggtgc aggcgtgcga cgaatcgagg ctgtaacaag
    23041 taaagaagcg tacgaactac ttgaagaaga agaaaaacaa ctaaaacaag tagcaacaat
    23101 tgttaaatca cctcaattga aagaagttgt ttcaaaagcg gaacaattgc aacagcaagt
    23161 aagagagcta caaaaggaaa atgaacaatt agctagcaag ttagcgaatc aacaagctgg
    23221 tgatgtattc aaagatccag aaacgatcaa tggaaaaaca atcattgcag cacaagtaaa
    23281 agtgaaagat atgaatcagc tgcgtcaatt agctgaccaa tggaaacaaa aaaatatttc
    23341 agatattctt gttttagcaa acgaacaaga aggaaaagtc agtctgctag cggcaatgac
    23401 gaaagaatca aatgaagctg gactaaaagc tggcgacttg attaaagcaa tcgcaccgaa
    23461 agtaggcggt ggcggtggtg gacgtccaga catggcacaa gctggcggga aaaatcctgc
    23521 tggtattcca gatgcactta aagctgcgaa agaatgggtt gcgcaacaat agggcgttta
    23581 cgtttgacag aaaaacaaaa gttcaaacat tgaacgaaac atgattatgg gggcgaagac
    23641 aaacaagtct tgccctcata cttttttcaa ttggatggcg catctaatca aatggtcgga
    23701 ttcggatggt ctttagttga cgaaagtgac agaaattttt acgattagta taaataaaaa
    23761 ggggtgaaaa aatgaatagt agaaataaga cctttcgact agtcttacgt gcgatcttgt
    23821 tagcaatcat catcgtacaa gcgatggttc cttggctggg gtttattcca ttaggattca
    23881 ttagtttaac aattatccat atcacagtaa ttattgctgc agtagtatta ggcccaaaag
    23941 atggcatggt gattggcttg ttttggggaa tcgctacaat tgttcgtgcc tatgccatgc
    24001 caacaacgcc atttgataca ttagtgttca cgaatccgat tatctcggta gttcccagag
    24061 tacttgttgg cttagtagca ggcttggttt tccactggat ttatcaaaaa aataaatcaa
    24121 taacgatcag ctcagccttt gcaggggtac tgggttcatt ggtcaataca gtcttagtgt
    24181 taggattcat gggattattt tatacaggtg caacggcaga tgcctatggt gtagactctg
    24241 ctcttttatt taaaacctta gcaggggttg cagcaatcaa tgggatacca gaagcaatag
    24301 gtgcgggaat cataacacca ttactagcaa aagcgttatt tgcagcaaca ccgttgaaac
    24361 cagaataatg accatctttt aatagtaata ggacgcacga tagatagaaa aaggaagaga
    24421 ggagaggaaa acaatcgtcc tctccatctt tttacctgag caacaagcaa actagaaggg
    24481 gtaaaaaact tggctaagaa acaagaagaa aaaaagaaac aaataccgca acagcggaca
    24541 aaaaaaggag tactagcggg tatcttagga ttggttacga atctgatctt gtttgtctct
    24601 aagctaatga tcgggctttt ttcaggaagt gtctccatta tggctgatgc agtgaacagt
    24661 ctatcagata ctgcttcatc catattgact ttgatcggat ttaaaattgc tgcaaagcca
    24721 gcagatcagg aacatcctta tggacacgaa cgcttcgaat atatcagtgg gttatttgtt
    24781 tcgatcatca ttacttatgt aggatttcaa tttttagagt cttctgctga aaaaatcatc
    24841 catccagaaa atgtctcttt aacacccatc gtcttttttg tcctaatcat ttccatcttt
    24901 ttgaaatttg cacaaggcaa aatgtatcag gttattgcgc aatccattga ttctgaaaca
    24961 ttgagagcta cagcaacaga tagttataat gatgtcttta ctacactggc tgtattgctt
    25021 tcagcagcaa tcgaatgggt aactggatgg cgtattgatg gatatatagg ttttgcttta
    25081 gcattatata tcctttatag tggattgacg atgcttcgaa attttgtata cgaactatta
    25141 ggaagtcgcc caacgccagc agagattgaa gaaatggaag agcatttaaa tgcttgcgat
    25201 gatatacttg gctatcatga tttattggtg cataactatg gacccaataa acgctttgca
    25261 tcagtccaca tcgaagtaga tgaatcaatg aatttgaatg tggctcataa gattattgat
    25321 ctgatagaaa aagactttaa aaagtctttg gatgtggaac ttgtctgtca cttggatcca
    25381 atgcctgttg ataacgaaaa atactataat atcttgcggc agttaaagca aattcttctt
    25441 gaaacaggta cagggcttaa tattcatgat tttagagtaa ttcatcaagg aaaaacgctg
    25501 caatttgatg tagtggtccc tgagaaattc cagtttgttg atacagaact agaaagaatc
    25561 ttacgtagtc aaatagaaga aaaaatcgga gattaccaat tggaaattac gtttgatcac
    25621 aattatcttt tatattaaat gagaaactat aaaaagactc cttaaagttt ttaatttaaa
    25681 gagtcttttt ttcttttaat tgtttatgga gagcctgacg tgcaagatta tctgctcctt
    25741 tatttttgtt ttcgggcaac cattgcagga tcaataaaga aaattcggat agaagttctt
    25801 ggattctttg aaggtaggga aggaagagct cgttcttcgt tgcgtttttg tcgaccgtag
    25861 aaactagtgt tttgctgtct gaaaaacaga aaatcgtttc attctgtaag tcgtttttct
    25921 ttagaaattc taaagttttt aaaaagactt cgaactctgc ttgatggttt gtccctatag
    25981 aaagcgggat agatagctgt tcttgtttac cttgatagac aatcaagatt ccacctccac
    26041 taggaccagg gttgcctttt gtagaggcat caatgtatac ttttaacata aaaagagatt
    26101 ctcctttttg ttcaaactaa tgttatggta agattatatc attactgaat cggtgagagg
    26161 ttagagaatg aaaaaaaata ttcgatggca gcctgaactg gcacatacga tcatctattg
    26221 gtcattgacc ttgatcattc tgttttttag tctgattctt tctttagaaa acacaggtcc
    26281 ttattggaaa agcaattttg ttttaggtat ttttcttgtt tttctatttc taggtttgcg
    26341 gcgttctttt attttaaaat caaactctgt gattatacgt tatgctgctt tttggaaaga
    26401 ccgagaaata tctgtcggac agattcgatc tttgacgcca actaatactg gggtgcaaat
    26461 gatgttgcaa gatgagaaag ccccatctgt tttcatgatg cgaaaaaaag atcaagtagt
    26521 cctttttgat cattttgaaa aaaacggacc caaatcagaa tcaattcctt atccttatac
    26581 gaaaaaaaga aaaagctaat tttaaaaatc agaacctaaa aaaacgaatt tttacaggaa
    26641 aagaaaagag tgagacgtac ggttcatccc gtttagcgtc tcactctatt tgtttatcta
    26701 ttcatgcata ctagtatcgg tagtctgaac gttgcctttc ttgacatggg cagcttgtgt
    26761 tcctcgattc ccttcgatga tctcaaattc gaccacttga ttttcttcca aagttttgaa
    26821 tccctcttct tcaatcgcag taaaatgtac aaaaatttct tctgtgtcat cataactgat
    26881 aaagccgtat ccttttttgt tgtcaaacca ttttacaatt cctgtggtca aagcactcac
    26941 gacctttcta aagtctgatc atagccttca ttataaagag tatttataag tacgtcaaat
    27001 aaattaaaaa cctgtaattt tatgtttttt ttctgaataa aaaaaggtat aattggcata
    27061 tcttaacaaa gaagatattt tgttgaataa agttcgtgaa aaggggtaat caaatgaaga
    27121 atgatctgca aatttcacaa gaaacagagc tagaaccgat tgttgaagtg gctagtaaat
    27181 tagatcttaa ggaagacgat ttggaactgt atgggaaata taaggcgaaa atcaattttt
    27241 ctggaatcaa tcgatcaaag gataacgctg aggggcattt gatcttagtt acttccatca
    27301 atccaacacc agctggcgaa ggaaagtcaa cgatcactgt agggttagga gacgcgctca
    27361 ataaaatcaa taaaaaatct gttattgcat tgcgagaacc ctcacttggt cctgtgatgg
    27421 gaatcaaagg tggtgctgca ggcggaggat atgcacaggt attgcctatg gaagatatca
    27481 acttgcattt tactggtgac atgcatgcta tcacaacagc taataatgca ttatctgctc
    27541 ttttagataa tcatattcat caaggaaatg aattgaacat cgatgcccgc cgagtgattt
    27601 ggaaacgggt agtcgatctc aatgatcgtg aactgcgtaa agtaattgtt ggcttgggtg
    27661 ggccaatcca aggtgttcca agagaagatg ggtttgatat cacagttgcc agcgaaatca
    27721 tggctatctt gtgtcttgcg gcagaccttg aagatttaaa ggctcgtctt gcaaggatcg
    27781 ttgtcggcta tacatttgac cgtcagcctg tgactgctgg agacttgaaa gcagaaggcg
    27841 ctctggcatt actgctgaaa gatgcaatca agccgaatct tgtacaaaca atttacggaa
    27901 caccagcttt tgtccacggg ggaccgtttg ccaatatcgc tcatggctgc aatagtattt
    27961 tagctaccaa gacagcattg agattagcag attacgttgt cacagaggca ggatttggtg
    28021 cagatcttgg cggagagaaa tttttagata tcaaagtacc taacttgaaa aaagcgccgg
    28081 atgctgtggt gattgtcgcc actgtccgtg cattgaaaat gcatggcgga atgaaaaaag
    28141 atgaacttaa aaatgagaat cttgatgctt tgaaagtagg ttttgcaaat ttaaagcgcc
    28201 atatacgtaa tatggaacaa tatcagctac ctgtgatcgt cgcaatcaat gaattcgtaa
    28261 cagatacaga caatgaactc acactgttgg agcacttgtg tgaaaatcag gggattcttg
    28321 ccaagagagc gagtgtatgg gcagatggag cagaaggcgg cgttgattta gcaaaagctg
    28381 tagtacgatt gattgataga aaagaagcta attacaagcc attataccgc ctagaagaaa
    28441 cgatacaaga aaagacagaa acaatcgtca agaaaattta cggaggaaat ggtgttgttt
    28501 tcagcaaaaa agcgcaaaaa caaatagaag agtttacgaa gaatggatgg gacaaactgc
    28561 cgatttgtat ggcaaaaaca cagtattcat tttctgatga tccttcactg ctaggtgcac
    28621 cggaagattt caccatcacg atccgcgaaa tcatcccaaa attaggggca ggatttttag
    28681 tagccttgac tggagatgtt atgacgatgc ctggtttgcc taaaaaacct gctgcattga
    28741 atatggacgt gacaaatgac ggagaagtgt tgggattgtt ttaagcttga ttataatcta
    28801 ccatcgaagg agctgtattt tgactacagc ttcttttttt agacgatagg gaattaattt
    28861 tgtttacact aggatcattc tttttcttta ttgtattttg agctatacta aagcataata
    28921 ggagggtatg atgaaaacga catttataag aaaaaccggt ttttacggta tgggtagctc
    28981 gattcagcta agaatcaaca atgaaaaacg cagtgttctc agtcatgaac aaaagataac
    29041 gcttgatctg gaagtgccct ttacgatgca ggtcaccttt tattggctaa aaagccccgt
    29101 ttatacagtg aaagaagcaa agcctgctta tgtgatcaca atgaattact tgattcttca
    29161 aatctatccg tttttatttc tagcaactgg gttgggggcc gttttcctac aaaatttatt
    29221 tttcagtttt tttgcagtta ttgtgttgat tgcgttcttt ttctatataa aaaaccgggc
    29281 atatttgatc aaggaggaaa attatggcaa actctgatct ttttttaatc agtttcaatc
    29341 gaatcgaaaa atggatgaga gacgagatgg gaaatgcacg aaatatggga tttaccgaac
    29401 ttgtcagacg cctagctcaa agaaaacaat taatgatcag aaaatacgaa gatgatcttt
    29461 tacagcttgc tcagttaagg aatgcgatcg tccatgatcg gatcgcagtc gattttgtca
    29521 ttgcagagcc aaatgattgg acagtcaagc gaatccagct gatcgaacaa gaactgattc
    29581 agcctgaaac cgtgctgcct cgatttgcaa aacgtgtaac aggttttgaa caagatcttc
    29641 cgttacttga actgttaaag atagtagcag aaaaaaggta ttcacaattt ccgttataca
    29701 ataaaggaaa atttgtagca ttgattactt tacgtaatat cgggttttgg ctagcaaaag
    29761 aaagccaaaa aggtccggtt gatttaacaa ataaacgagc gttggatttg atcatccaaa
    29821 acggaaagta cacaaattat cattttgttc cagctaaaac acatatttac gaggttgaag
    29881 cgatgtttcg tgagcaaggg actttggaag ccgtacttat cactaaagat gggaatcccg
    29941 atggtaatct gctcgggatc gtacgacctc gtgatattta taaacaaata gaaaaggatt
    30001 gattttttgt taattattta ttggatattc agcgctttgc tagtaggagt ggatcagttg
    30061 gtcaaatggt ggatcactga taatctagcg cttggagaga cgaaaaatct tataccaggt
    30121 attttgtcac tgaatcatat tcgaaacact ggagccgcat ggagtatgct agaagggaag
    30181 atgtggttct ttactatagt gacactcatt gcagtcgttg tgattctcac attgatgatt
    30241 aaaaatcgtg aaaaaggtaa tcgctggttc atgattggat tgagtttgat tctagctggt
    30301 gcgattggca attttatcga ccgtattcgt cttggctatg tagtagatat gttccagaca
    30361 gattttatga gctttccgat ttttaacgta gcagatgtga cacttgtatg tggagtgatt
    30421 tgtatgttaa tttatattat tttagatgaa aaggatcaaa gaaaaaaatg acagaactta
    30481 aaacgacgat tcaccatgaa tctggtagga tcgataaagt attgactaat ttattcaccg
    30541 attacagtcg ttcgcaaatt cagctgtggc tgaaaaatgg agcggtttct gtcaatggac
    30601 agccagtcaa agcaaattac aaagtaaaac aaggagacga gattactgtc ttgatccccg
    30661 aaccagaaac attagatgtg gtcccagaaa atatcccgtt gacgatcgtt tacgaagatg
    30721 aagatgtagc ggtgataaac aaacctcaag gaatggtcgt tcatccttca gcaggtcata
    30781 cgcatggcac aatggtcaat gcgctgatgt accatatcaa ggatctttct acgatcaacg
    30841 gcgttattcg tccaggtatt gttcaccgaa tcgacaaaga tacttccgga ctgctaatgg
    30901 ttgccaaaaa tgaccaggca cacgaatcat tagctcagca attaaaagat aagacctctt
    30961 tgcgcaaata tgttgcttta gtccatggag agattcctca cgaaaaagga accatcaatg
    31021 cgccaatcgg ccgttcgaag gaaaaccgga aaatgcaggc gataagagaa gatgggaagt
    31081 cggctgtcac acattttact gtattggaac gtttcgaagg atttactctg gttgaattaa
    31141 aactagaaac cggaagaaca caccagatcc gtgtgcatat gaagtatatc ggttatccgt
    31201 tagctggaga tccagtatac ggaccgaaga aaactttgaa aggcaatggt cagtttctcc
    31261 atgcgcaaat gttaggtttt acgcacccga ctacaaacga aaagatgatc tttgaagcac
    31321 ctcttccaga agtttttgaa aaaactttag aaaaattaag aaaaaacatt gcattttaat
    31381 ttagataacg gtatagtaat taacaacgaa agcataaaac ttaatagaat tcctttaagt
    31441 ttagtcccgt gaggctaaga agggtgggag caaggatacg tatggtgcgc cataagtaga
    31501 ttgctcattg acatagtata gctatcagtg tatcagtata cgctcagtct aaacattcct
    31561 cctgtcctct tagggcagga gtttttttat gcaaaaaagt agggggaatg aaaatgcaag
    31621 caaaagaagt agtagatcag gtaaccatga agcgagcatt gactcgaatt acttatgaga
    31681 ttatcgagag aaaccatagt atccaagata tcgtattggt aggtatcaaa acacgaggaa
    31741 tctacattgc atcaagaatt gccgaacgcc tgaagcagct agaagatatc gatattcctg
    31801 taggagaact ggatatcact ttataccgag atgacaaaaa agaaaatcca gaagaaccgg
    31861 aacttcattc ttctgacatc ccagtttcct tagaaggaaa agaagttatt ttgattgatg
    31921 atgttttgta tacaggacga acgattcgag cagcaatgga cgcagtaatg gattttggca
    31981 gaccaagaaa aatttcatta gcagtcctgg tcgatcgtgg gcatcgagaa ttgccaatcc
    32041 gtgcagatta tgttgggaag aacattccaa catctcgggc ggaagagatt ttagtagaga
    32101 tgcaagagct tgatggacaa gatcgcatca tgattttgaa agaggaagat tagaggagag
    32161 agaaacatgt cggagaaaaa aggatttcat aatgatgacg tggtgttaga tatccacgat
    32221 cgcccaaccc caggacattg ggtaggatta agtttacaac acttgttcac gatgttcgga
    32281 gcaaccgtgt tagtccccat cttagtaggt atcgatccag gtattgcgct agtcagttca
    32341 ggactaggta cattggtgta cttatttact actaaaggaa agatacctgc gtacttagga
    32401 agcagcttcg ctttcattgc agcgatgcag cttttgatga aaacagatgg ttatccagcg
    32461 attgcacaag gagcagtcac aactggatta gtctatttga ttgttgcgct gatcatcaaa
    32521 aagatcggtt cagcatggct ggataaaatc ttgcctccaa tcgtcgtcgg tccagtcatc
    32581 atggttatcg ggttgggact tgcggcaaat gcagcaacaa atgctatgta taatcagggc
    32641 acgtatgatt tcaagtatat tgctgtagcg ctgatcacat taggattaac aattttcttc
    32701 aacatgtggc taagaggttt tctcggattg attccgattt tactaggtat tattagcgga
    32761 tacatcgtag ccttgctgtt tggaatcgtg gatactaagc caatcgtaga cgctgcctgg
    32821 tttgctgttc ctaactttga gattcccttt gtacaatatg aaccaaagct atatcttgga
    32881 gcaatcacaa caatggcacc catcgctttt gtgacgatga cagagcatat cggccatctt
    32941 atggtattga ataaactaac taaacgtaat ttctttgaag aaccgggtct tcataagacg
    33001 ttgacaggtg atggattagc acaaatcgtg gcagcctttg tcggaggtcc tcctgtaaca
    33061 agttacggtg aaaacattgg tgttctggct atcacacgtg tccatagcgt gtttgtgatc
    33121 ggtggagctg cagtatttgc agtcatttta ggattcgtag gaaaattaag cgctttgatt
    33181 ttaagtatcc ctggaccagt catctcagga atcagtttta tcttatttgg agtaattgcc
    33241 gcaagtggaa tgaagatttt aatcgagaac aaaatcgatt ttgataaaaa gaaaaatctg
    33301 ttgattgctt cagttatctt agtagtagga attggcggac tcgtctttga agtaggcaca
    33361 tttacattgt cggcaatggc attagcaact gtacttggca tcattttaaa tcttatctta
    33421 ccagaaactt cacgaagcga agaaaactaa ggaggaaaca ttatgatcat caaatcagaa
    33481 cgtatcagct taaagcattt attgaccgtt gaggcactta ctgatcaaga agttatgggc
    33541 ttgatccgca gagggcagga attcaagcaa ggtgctaatt ggactccgca aaagcgccag
    33601 tactttgcta caaacctctt tttcgaaaat agtactcgca cacataaaag cttcgatgta
    33661 gcggagaaaa aactagggct agaagtgatt gaatttgaag caagcacaag ctctgtccaa
    33721 aaaggggaaa cactatacga tacagtactg acgatgtcag cattaggcgt agacgtagcg
    33781 gttatccgtc atggtgatga gaactattat gacgaactga tacaaagtaa aacaatccag
    33841 tgttcgatta tcaatggagg agacggaagc ggacagcatc caacccaatg cttgcttgat
    33901 ttgatgacca tttatgaaga atttggtcat tttgaaggtc tgaaagttgc catcgtaggt
    33961 gatatcactc actctcgcgt agctaaatcc aatatgcaga tgttaaaacg tctaggcgca
    34021 caagtattct tctcaggtcc tagagaatgg tacgacgatg aattcgaagt gtacggacat
    34081 tatatgccat tggatgaact actagatcaa gttgatgtca tgatgatgct tcgggtgcaa
    34141 cacgaacgcc atgatggaaa agaaagtttc tcaaaagaag gctaccatca ggaacatggg
    34201 ttaacagttg agcgtgcgaa gaagttgcaa aaacatgcaa tcattatgca cccagcacca
    34261 gttaaccgtg atgtagaatt agctgattca ttagtggaag gattacagtc gcggatcgtt
    34321 cagcaaatga gcaatggagt attcgtcaga atggcaatct tagaagcagt gctaaatgga
    34381 aaagcgtaat tataggagga tgaaaaaatg aaaacactca ttaaaaacgg tcagatcaat
    34441 acacgaaaaa atatgacgac accagcagaa atttggatag aagatgggcg aatcaaagca
    34501 atcggtacag gattctcaga agccgaattt gatgaagtgt ttgatgcaaa gggacaattg
    34561 atcacacctg gtttagtgga cgtccatgtt catttgagag agccaggatt tacatacaag
    34621 gagacgatcg aagctgggac tcgctcagct gctcgtggcg gtttcactac tgtatgcgcg
    34681 atgccgaatt taaatcctgt acctgatacg gcagaaaagc tgagacaagt atatgacatc
    34741 attagaaaag atgcagttgt gaaggtattg cagtatgcgc caatcacaga aaatctgcga
    34801 agtgagaaat tagttgatca agaagcactg attgaagaag gtgcttttgc tttcacaaat
    34861 gacggtgtag gtgtccaaac agctgggacg atgtatctgg ctatgaaaga agctgcaaaa
    34921 aacaataaag ccctagtagc ccatacagaa gatgaatctt tattatttgg cggcgttatg
    34981 cacgctggca agaaggcaga agaacttggt cttcccggga tcttaagcgt aaccgagtct
    35041 tctcaaattg ctagagatct gttgctagct gaagcaactg gtgttcatta ccatgtttgc
    35101 catgtttcta ctaaagaaag tgtccgtgta atcagagacg caaaaaaagc aggaatccac
    35161 gtaacagcag aagtttcacc ccatcatctt attttgatcg acgaagatat tcccgaagat
    35221 ttcggctttt ggaaaatgaa cccgccgcta agaggacggg aggacagaga agctttgatc
    35281 gaaggcttgc ttgacggtac gatcgattgc atcgctacag accatgcccc ccatggatta
    35341 gaagaaaaaa gccaaagttt catgaaatca ccatttggta tcgtaggaag cgaaacagcg
    35401 tttcaactga tctatactca ttttgtagaa actggtcgat tcacgttgga acaagtgatc
    35461 aattggttgg cagttaaacc ggctgagatt tttggtttga atgcaggaac gctaacggtt
    35521 ggtgcccccg ctgatgtagc agtttttgat attacacaaa cttgcacgat cgataaagaa
    35581 gactttttat caaaagggga gaatacacct tttatcggct ggaaagtaaa aggcgaaaca
    35641 caaatgactt ttgtcaacgg aaaacttgtg tggcagaagg gagaataaaa gtatggaacg
    35701 tttgcttata ttagaagatg gaacagtttt cgaaggaaag gcttttggtg cagatgctag
    35761 tgtcttcgga gaaatcgttt ttacaacaag tatgactggt tatcaagaaa ctatcactga
    35821 tcaaagtttt aacggtcaaa tcattacatt tacctatcct atggtgggta attatggggt
    35881 aaatagagat gattatgaat cgatttctcc aacatgcaaa ggagtagtag taaaagaaca
    35941 tgcacgtgta gcttcaaact ggcgaaacca aatgacgcta gattcatttt tgaaacaaaa
    36001 aggaattcct ggaatatcag gtatcgatac gcgcgccctt actcgcaaaa tccgtgaagt
    36061 cggaacgatg aaagctagta tcgttgatgc tggagattcc ttcgaacatg catttgatca
    36121 gctgaaagca accgttctag caaccaatca agtgcagcaa gtctcaacta acaaacctta
    36181 tccaagtcca ggaacaggtc ggaaagtcat tgtcattgac ttcggcttga aacatagtat
    36241 tttacgagaa ttgagtaaaa gaaactgtaa cctcacagta cttccctata acacagatgc
    36301 cgagacgatt ttagcgctat caccagacgg agtcatgctg acgaatggac ctggtgatcc
    36361 aaaagatgtg ccagaagcaa tcgaaatgat caaaaaaatc caaggaaaag taccgatttt
    36421 tggtatttgt ctcggtcacc agttatttgc tttagccaac ggtgcagata cctataaaat
    36481 gaaattcgga catcgaggat taaatcaccc ggtacgagaa gtagcgaccg gaagaattga
    36541 ttttacttct caaaatcatg gctatgcagt cgatgaagcc acgattgatc cagaaaaact
    36601 catcgtaact catgtagaag taaatgacgg aacagtagaa ggagtcaaac acagagatta
    36661 tcccgctttc agtgtgcagt ttcatccaga tgctgcccct ggtccgcatg atgcactaca
    36721 tttatttgat gaatttatgg aaatgatgga cgcaggaaag gagcagtaaa cagatgccga
    36781 aacgtacaga tatcaagaaa attatggtga ttggatctgg tccgatcatc attggtcaag
    36841 ccgcagaatt tgactacgca ggaacacaag cctgccttgc cttaaaagaa gaaggatatg
    36901 aagtggtttt agtaaattct aatcctgcga cgatcatgac ggataaagaa gtggcagatc
    36961 aagtatatat cgaaccgatc acacttgaat ttgtatcaag gattcttcga aaagagcgtc
    37021 cagatgctct ccttccaact ttaggcggac agacaggcct caatatggca atggagctgg
    37081 cagcatcagg tattttagaa gaattgaaca tagaacttct aggaacaaag ctttctgcga
    37141 tcgatcaagc agaagatcgt gatctattca aacagttgat gaaagaattg aatcagccaa
    37201 tccccgagtc tgaaatcgtc aatacagtag aagaagctgt agattttgca aataaaatcg
    37261 gctatcctgt catcgttcgt ccagccttta ctttaggcgg aactggtgga ggtatgtgtg
    37321 aaaatgaaga agaattacgt atcgtatcag aaaatggatt aagtctttcc cccgctaccc
    37381 aatgtttgat tgaacgaagt attgcaggtt ttaaagaaat tgaatatgaa gtgatgagag
    37441 attcggctga taatgcaatc gttgtctgca atatggaaaa ttttgacccg gtgggtatcc
    37501 atacaggtga ttctatcgta tttgccccta gtcaaacatt gtctgaccat gaatatcaaa
    37561 tgcttcgtga tgcttctctt tcgattattc gagcacttaa gatcgaggga ggctgtaatg
    37621 tccaactcgc tcttgatcca catagtttta attattatgt gattgaagtc aatccgcgtg
    37681 tttctcgttc atctgcgtta gcaagtaagg cgactggcta tccgatcgct aagctagctg
    37741 ctaaaatagc gcttggatta acattagacg aaatgaaaaa tcctgttaca ggaacgactt
    37801 ttgcagaatt tgaacctgca ttagattatg ttgtagctaa aattcctcgc tggccgtttg
    37861 ataagtttga aaacggagaa cggcttttag gcacgcagat gaaagcaact ggtgaagtga
    37921 tggctatcgg tcggaatatc gaagagtctt tattgaaagc tgtgcgttct ttagaaatcg
    37981 gtacacacca tatcgaactt cctgagttgg cagacatcac ggacgatgac ctaatccaaa
    38041 aagtggttcg agcacaagat gatcgcctgt tttatgtagc tgaagctatt agaagagggt
    38101 acaccataga agaattagcg gatttgacaa aaatcgattt attcttttta gataaactgt
    38161 tgcatatcgt agaaatcgaa cagcagttga aacagcagcc gttggatgac aagatattga
    38221 aaacagcgaa acaaaacggt tttacagaca aaaaagtggc ggagctgtgg gaaataaacg
    38281 aagaagccgt tcgccagatg agaaaagaaa atgatttgat tcctgtatat aagatggttg
    38341 acacttgtgc agcggaattc gaatcaaaaa caccttattt ttatagttcc tatgaatatg
    38401 aaaatgaaag ttcacgatca gaaaagccct caattctagt actgggatct ggtcctatcc
    38461 gtatcggaca aggggttgaa tttgactatg cgactgtgca ttctgtcaaa gcaatccagc
    38521 aggcaggata cgaagcaatc atcatgaaca gcaatcctga aacagtttcg actgactttt
    38581 ctatttcgga taaattatat tttgagccat tgaccttcga agatgtgatg aatgtgatcg
    38641 agctagaaca gccgatagga gtaatcgttc aatttggtgg tcagacagca atcaacttag
    38701 ccgaaccttt gactgctgct ggtgtaaaaa tcttagggac aacgatcgaa gacttggatc
    38761 gtgcggaaaa tcgtgattta ttcgagcaag cgctgaaaga gttggatatt cctcaacctt
    38821 taggggatac tgctacaagt aaagaagaag ccgtggttat cgcttcgaga attggttatc
    38881 cagttcttgt tcgtccaagc tatgtattag gcggacgtgc gatggaaatc gttgaaaacc
    38941 agcgagattt agaagattac atggaacatg ctgtgaaagc atctccagaa catccagtac
    39001 tagtggaccg ttacttgctt ggtggtgaat gcgaagtgga tgcgatttgt gacggtgaaa
    39061 cagtactcat cccagggatc atggagcata ttgagcgtgc tggtgtccat tcaggggatt
    39121 caatggctgt gtatccacct caaacattat ctgaatcgat caagaaaacg atcgaagatt
    39181 acacgatccg cttagcatta ggtttgaatt gtgtcgggat gatgaatatc cagtttgtca
    39241 tccatgaaaa tgaggtttat gtgatcgaag tcaatcctcg agcaagtcgg actgttccat
    39301 tcttaagtaa ggtgacagga attccaatgg cacaaattgc gacgaaagct attttgggag
    39361 agaaactaaa gacacttggt tatgaaaacg gactttatcc agaaacaaaa gaagttcatg
    39421 ttaaagcacc tgtcttttct tttacgaaat tgcagaaagt tgatacttac ttagggcctg
    39481 aaatgaaatc gactggagaa gtaatgggat ctgacagaca attagacaaa gctttgtaca
    39541 aggcattcga agcttctgga ttacacttgc ctgaatatgg agccgtatta tttacgattg
    39601 cggacgaaac aaaagaagaa gcactagaat tagctaaacg ttttacagaa attggctata
    39661 gtctgatagg aacgaaacat acagctgctt atttcgaaaa aaatggtctg gtcgttgaaa
    39721 cagtagcgaa aatttctgag gaagcagcag aaaaaaatgt agtcgactta ataagagatg
    39781 gtaaaacaca agtggttgtc aatacgattg ataaagatcg gggaaatgct tctaaagacg
    39841 gtttcatcat ccgaagagaa gcagttgaac atggtattcc attgtttact tctttagaca
    39901 cagcagatgc gatcgttcga gtgatggaat cccgtgcttt ttcaactaac cctatttaac
    39961 ggcgagcaca tgttaagaca aaaagacgaa aaaccgttgc aggaggggac agatgaaaca
    40021 agaaatgatg gaaatcgttc agcaaaaaca gctggcacca aagatttttg aaatgacatt
    40081 gaaaggtgat ctagtaaaag aaatgcagca accaggacag ttcttgcata ttctcgtgcc
    40141 gcgtgcagac ttgctattac gccgaccgat tagcttgaat catatcgacc acgaaacaaa
    40201 tacttgccgt atcatttatc gggtggaagg tgaggggact agagtcttct ctactctttc
    40261 tgccggagac catttagatg tcatgggtcc tttaggcaat ggttttgatt tgtccaatct
    40321 tcatacagga gacgaagtat ttataatcgg tggaggaatc ggtgtccctc ctctatatga
    40381 gttatcaaaa cagttagtcg aaaaaggaat taagccaacg cattttttag gttttgccac
    40441 acatgaagtc gtttattatg aaaaagaatt taatcgtcta ggagaaacaa gaatcgctac
    40501 tgacgatgga acatacggta tgcacggaaa tgtcggtaat ttattgttag gaacgaagac
    40561 ggaacctaca gctgtttttg catgtggttc aaacgggtta ttgaagacag tggaacagct
    40621 gttttcttcg catcaaaatg tccagttatc attagaatcc cgcatggcat gtgggatagg
    40681 ggcttgctat gcttgcgttt gtcatacgcc ggaagatgaa acaggaacaa aaagtgtgaa
    40741 agtttgtgac gaaggaccga tttttaaaat aggagaggta attatatgaa tgagaatcct
    40801 ttagcggtca aacttcctgg cctagaatta aaaaatccta tcatgccggc aagcggctgt
    40861 ttcggttttg gcaaagaata cggaaaatac tatgatttga atcagcttgg atcgatcatg
    40921 gtcaaggcaa cgactccaaa tgcccgcttt ggcaatccca cgccaagagt ggcggaaaca
    40981 ccatctggca tgttgaatgc aattggtttg caaaatcctg gtctagacgt tgttatgcat
    41041 aaacttcttc cagaattaga ggagtacaat gagttaccca tcatcgcaaa tgttgctggt
    41101 gcttgtgaag aagactatgt agaagtttgt agcaaaattg gcgaagcacc aaatgtgaaa
    41161 gcaatcgagc tgaacatttc ttgcccaaat gtcaaacatg gcggaattgc ttttggaaca
    41221 gattctgatg ttgcttttca attaacacaa gcagtaaaga aagtttcttc tgttcctgtc
    41281 tatgtcaaat tgtccccaaa tgtaacagac atcgttccaa tcgctcaggc aatcgaagct
    41341 ggaggggcag atgggtttac gatgatcaat actcttcttg gtatgcggat tgaccttaag
    41401 acaagaaaac cgattttagc caatcaaaca ggtggactct ccggaccagc aatcaagcct
    41461 gtcgctattc gtttgattca ccaagtagca agtatatcca gccttccaat cattgggatg
    41521 ggcggcgtgc agacagtgga tgatgttctt gagatgttta tggctggagc aagtgctgta
    41581 gctataggga ccgcgaattt caccgatccg tatatctgtc ctaaactaat taaagagctc
    41641 cctgtgcgaa tgagcgaact aggcatcgaa tcgctggaaa gattaatcaa agaagtgaga
    41701 gaggaacgtg aacgatgaat caactagacc aacgaccaat tattgcatta gatttttcaa
    41761 ctaggcaaga ggtagaagac tttcttcgat ttttcccgaa agaagaaaaa ttgtttgtga
    41821 aaatcggaat ggaattgttc taccaagaag gacctgaaat cgtacgttat ctaaaagagg
    41881 ctggtcataa tgtattttta gatctgaaac ttcacgatat tccgaatacg gtcgaaaaag
    41941 caatgcgggg attggcaaag cttggtgttg atctcacctg tgttcatgcc gctggcggta
    42001 ttcgtatgat ggaggcggca atgcgaggat tagaagaggg gactccagaa ggtggaaaac
    42061 gtccgctact tctagctatc actcagctta cttctacaag tgaagaagaa atgcatgccg
    42121 atcaactaat cgaagtttct ttagaaaaaa gtgtgatcca ttatgctagc tgtgccaaaa
    42181 aagcaggatt agatggtgtg gtttcttctg cttgggaagt agaagcgatc aaagaaatgg
    42241 caggagacga atttgtttgc ttaactccgg gtataagacc agaaggaaca gtcgcaggag
    42301 atcagacaag agtagtcaca ccttctcagg caaaaaagat cggctcaact tttatcgtta
    42361 taggtcgacc aatcactcag tcaactaatc cttataaagc atatcaaacg attcaaacag
    42421 aatggagcta acctaaaatg aatgttgaac aaagtatcgc aaaagactta ttagaaattg
    42481 aagcagtatt tttaaatcca agtaatcctt ttacatgggc aagtggaatc aaaagcccaa
    42541 tttactgtga taaccgaatc acgatgagct atccaaaagt ccgaaaagag atcgcaaaag
    42601 gattagcaag caaaatcaaa gaagcttacc ctgaagtaca agtgattgct ggaactgcaa
    42661 cagcaggaat ccctcatgcc gcatgggtag cggaaatact ggatttgcca atggtctata
    42721 ttcgaagtaa ggcgaaagat catgggaaag gtaaccaaat cgaaggacgt atatttgaag
    42781 gtcagaagat ggttgtgatc gaggatttga tttctacagg cggaagtgtc ttggaagcag
    42841 ctgaagcagc aaaaagagaa ggtgcggata tccttggtgt tgcggctatc tttacgtatg
    42901 agttgccaaa aggaaaagca aatttcgaaa aagccgaaat ccctcttatg acgttgacca
    42961 attattctgt attgattgaa gcagctttag aagatcgtta tatcgatgag caagaattaa
    43021 ctctgctaaa agaatggaaa aaagatcctg aaaattggca gatttaagcg cgcttgatga
    43081 agatagagaa atccgatttg tgtctccaga atcatcaatt ggaatagcaa aaatccaaaa
    43141 actgattgcg agaagcatct tttcatcagg tatgaaaaga aacttctatc gtgatcagtt
    43201 tttgattttt ttaaaattca tttttctaag actggttagc agaaagaaga gaataatctc
    43261 ttctcttttt tctattatat atagattttc tctatttttt ggtaagggag ctgtttcaaa
    43321 aatggtaaag agcggaaatg ttgcgaatat cagttattta atgatatgat attcggaaaa
    43381 agaaatctca aagggaggta acttttatgg ggttgaatga atttatttta ggattgaaca
    43441 atttagagac gatcacaagg gcacctggat tttttaaata tacagagcat acagttgcag
    43501 cacattcgta tcgtgtagca tctattgcgc aagttctagg agacattgaa gaagcgaatg
    43561 gacaaccgat cgattggaaa ctgctctatg aaaaatcatt gaatcatgac tacacagagc
    43621 gttttattgg tgatatcaaa acgccggtga aatacgcaag caaagagtta agagggatgc
    43681 tgcaaacagt tgaagaaaag atgacggacg aattcatcaa ccaagagatt ccagctgagt
    43741 tccaagaagt ttatcgccgt cggttgttcg aaggaaaaga tgaaaccgta gaaggagaac
    43801 tattagccat ttcagataag gttgaccttc tttatgaatc ttttgatgaa atcatcaaaa
    43861 ataacccgga aaaagtttat aaggagatgt tcattgaggc agtgactacg attaaaagct
    43921 ttgaacatcg gccttctgtt cagtatttct ttaaagagat atttccggaa ctattgaacc
    43981 aggaatttta tggaaaagag gcgtttttag aaaccgtctc aacgattgta aagaaagaag
    44041 aaaaataaaa atgatatgag atgcaggggg aagtatagtt gaaaaagaat atggatgtcg
    44101 aatggggcta ttctggagac aaaggtccgg aaaattgggc gagtttatgt gattggtttg
    44161 cgagaggtgc ggaatttcca ttgcagtcgc ctattcattt gaccaagggg gaagaaacca
    44221 aaatagaagg agacacgctt tcctttcatt atcaaaagca acggtttact gacaaggaat
    44281 tcaaaaacac gattcattta gtaccttttg accaactcag ttatgtagag ttcaagaaag
    44341 aacgctatta tttgacagat attcatttcc acttgccttc tgaacatatc atcaacggaa
    44401 aacaggaaga tattgaattt cattttgttc atatgaacag caaaaaagag aatctagttg
    44461 tgggtgtcat gtaccagcta atggtacagg aaggttggct gtataatcaa gaaaatgggg
    44521 aaagttggaa cttagaaaaa catgagcatt gggtaaatcc ggatgtgttc tttccggagc
    44581 aaaaaagcca tttccattat attggctcat tgacaactcc gcctaccagc gggccaatcc
    44641 aatggtttgt aatggatcat gtaggaaaac tgaaccaaga gtttcttctc cccttcgatg
    44701 gtcagtatgc tcgaccgaac aaccgaccaa tccagccctt gaatggaaga gaaatttatt
    44761 atttcgagga gtttgagcaa tgaatattca gcagatgaaa tacgtggtcg ctgtagcaaa
    44821 caatggtagt ttcagagaag cggcaaagaa aatgtttgtc tcccagccaa gtctttcagc
    44881 tggtatcaaa gaattagaaa ccgagttagg gatcacgctg tttactcgaa cgaatcgagg
    44941 ggcatattta acagaagaag ggcaagactt cttaaatcgt gccgagaaaa tattggtcca
    45001 gcttgataca ttagaaactc actatctaac gagtgaaaag agagacaatt tttcgatcgc
    45061 tgcccagcat tatgatttct taggtccttt gaccgcacag ctactcgagg aattcaaaga
    45121 cgagatcaaa caatttcgga tcatggagac gacaacagcg agagtgatcg aagaagtcaa
    45181 agagcagcac agtgagatcg gcattattta tatgaatgag cataatcaag ctggtatcag
    45241 aagatattta caacaaggag agctaagtgg ccgcagcatt ggaaaattca aaacgcatat
    45301 ttttttaagg caaggacatc cattagctga acacgcagag atcaccaaag aagaattgtt
    45361 atcttatcct caagttcgtt ttacacagga tggaaataat ttcccgtatt tttatgaaga
    45421 ccttatcgag atccctgatc aagaaacagt gatttatacg agtgatcgag gtactttgat
    45481 gaatatcgtt cttgaaactg atgcttacgc ttcaggatct ggtattgtga ttggagggat
    45541 tcgcgagcac ttgcggttaa tccctttggc agaaggcgaa ctaaatgaat tttatatcat
    45601 ttattcggcg aaacgtccgc tcagtgaaat cgctcaaaga tttatcaaag agcttactcg
    45661 gttactggac cagcagagct aagaaaagca gatgagaacg ctgtttattg aacaccgttg
    45721 atcaaaaaag aggggttgtg acagaatttt gtcacaactc ctctttttgt agcaaacaat
    45781 t
//
LOCUS       DAXQKX010000019        41373 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.019, whole genome shotgun sequence.
ACCESSION   DAXQKX010000019 DAXQKX010000000
VERSION     DAXQKX010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 41373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41373
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.019"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..411
                     /locus_tag="ACF3MF_001125"
     CDS             <1..411
                     /locus_tag="ACF3MF_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HFE3927136.1"
                     /translation="GLYYSPVSTPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAP
                     QEYLSRAYNDAPKYCANIVNTQLKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLA
                     ELKGYQVTTGEPVCQTRRLNSRIDKVRYMFNKIT"
     gene            509..697
                     /locus_tag="ACF3MF_001126"
     CDS             509..697
                     /locus_tag="ACF3MF_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HFE3927137.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(755..1108)
                     /locus_tag="ACF3MF_001127"
     CDS             complement(755..1108)
                     /locus_tag="ACF3MF_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3927138.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            1639..2061
                     /locus_tag="ACF3MF_001128"
     CDS             1639..2061
                     /locus_tag="ACF3MF_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFE3927139.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            2058..2288
                     /locus_tag="ACF3MF_001129"
     CDS             2058..2288
                     /locus_tag="ACF3MF_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3927140.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            2786..2986
                     /locus_tag="ACF3MF_001130"
     CDS             2786..2986
                     /locus_tag="ACF3MF_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000633907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HFE3927141.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            3013..4206
                     /locus_tag="ACF3MF_001131"
     CDS             3013..4206
                     /locus_tag="ACF3MF_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFE3927142.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(4274..5839)
                     /gene="guaA"
                     /locus_tag="ACF3MF_001132"
     CDS             complement(4274..5839)
                     /gene="guaA"
                     /locus_tag="ACF3MF_001132"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HFE3927143.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(5898..6821)
                     /gene="coaA"
                     /locus_tag="ACF3MF_001133"
     CDS             complement(5898..6821)
                     /gene="coaA"
                     /locus_tag="ACF3MF_001133"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HFE3927144.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            7017..7622
                     /locus_tag="ACF3MF_001134"
     CDS             7017..7622
                     /locus_tag="ACF3MF_001134"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFE3927145.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            7930..8946
                     /locus_tag="ACF3MF_001135"
     CDS             7930..8946
                     /locus_tag="ACF3MF_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFE3927146.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            9087..10388
                     /locus_tag="ACF3MF_001136"
     CDS             9087..10388
                     /locus_tag="ACF3MF_001136"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HFE3927147.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            10434..11096
                     /gene="deoC"
                     /locus_tag="ACF3MF_001137"
     CDS             10434..11096
                     /gene="deoC"
                     /locus_tag="ACF3MF_001137"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HFE3927148.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            11117..11515
                     /locus_tag="ACF3MF_001138"
     CDS             11117..11515
                     /locus_tag="ACF3MF_001138"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HFE3927149.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            11581..12663
                     /locus_tag="ACF3MF_001139"
     CDS             11581..12663
                     /locus_tag="ACF3MF_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HFE3927150.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            12875..14437
                     /locus_tag="ACF3MF_001140"
     CDS             12875..14437
                     /locus_tag="ACF3MF_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3927151.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            14430..15563
                     /locus_tag="ACF3MF_001141"
     CDS             14430..15563
                     /locus_tag="ACF3MF_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFE3927152.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            15563..16519
                     /locus_tag="ACF3MF_001142"
     CDS             15563..16519
                     /locus_tag="ACF3MF_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFE3927153.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            16618..17784
                     /gene="deoB"
                     /locus_tag="ACF3MF_001143"
     CDS             16618..17784
                     /gene="deoB"
                     /locus_tag="ACF3MF_001143"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HFE3927154.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            17808..18626
                     /locus_tag="ACF3MF_001144"
     CDS             17808..18626
                     /locus_tag="ACF3MF_001144"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFE3927155.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            18643..19350
                     /gene="deoD"
                     /locus_tag="ACF3MF_001145"
     CDS             18643..19350
                     /gene="deoD"
                     /locus_tag="ACF3MF_001145"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFE3927156.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(19648..20334)
                     /gene="gpmA"
                     /locus_tag="ACF3MF_001146"
     CDS             complement(19648..20334)
                     /gene="gpmA"
                     /locus_tag="ACF3MF_001146"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HFE3927157.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(20506..21087)
                     /locus_tag="ACF3MF_001147"
     CDS             complement(20506..21087)
                     /locus_tag="ACF3MF_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFE3927158.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(21220..21903)
                     /gene="rpiA"
                     /locus_tag="ACF3MF_001148"
     CDS             complement(21220..21903)
                     /gene="rpiA"
                     /locus_tag="ACF3MF_001148"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HFE3927159.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            22222..22635
                     /gene="rpsL"
                     /locus_tag="ACF3MF_001149"
     CDS             22222..22635
                     /gene="rpsL"
                     /locus_tag="ACF3MF_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HFE3927160.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            22719..23189
                     /gene="rpsG"
                     /locus_tag="ACF3MF_001150"
     CDS             22719..23189
                     /gene="rpsG"
                     /locus_tag="ACF3MF_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HFE3927161.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            23283..25370
                     /gene="fusA"
                     /locus_tag="ACF3MF_001151"
     CDS             23283..25370
                     /gene="fusA"
                     /locus_tag="ACF3MF_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HFE3927162.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            25542..26729
                     /gene="tuf"
                     /locus_tag="ACF3MF_001152"
     CDS             25542..26729
                     /gene="tuf"
                     /locus_tag="ACF3MF_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HFE3927163.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            27136..27444
                     /gene="rpsJ"
                     /locus_tag="ACF3MF_001153"
     CDS             27136..27444
                     /gene="rpsJ"
                     /locus_tag="ACF3MF_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HFE3927164.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            27475..28104
                     /gene="rplC"
                     /locus_tag="ACF3MF_001154"
     CDS             27475..28104
                     /gene="rplC"
                     /locus_tag="ACF3MF_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HFE3927165.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            28132..28755
                     /gene="rplD"
                     /locus_tag="ACF3MF_001155"
     CDS             28132..28755
                     /gene="rplD"
                     /locus_tag="ACF3MF_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HFE3927166.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            28755..29045
                     /gene="rplW"
                     /locus_tag="ACF3MF_001156"
     CDS             28755..29045
                     /gene="rplW"
                     /locus_tag="ACF3MF_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HFE3927167.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            29084..29917
                     /gene="rplB"
                     /locus_tag="ACF3MF_001157"
     CDS             29084..29917
                     /gene="rplB"
                     /locus_tag="ACF3MF_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HFE3927168.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            29960..30238
                     /gene="rpsS"
                     /locus_tag="ACF3MF_001158"
     CDS             29960..30238
                     /gene="rpsS"
                     /locus_tag="ACF3MF_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HFE3927169.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            30261..30608
                     /gene="rplV"
                     /locus_tag="ACF3MF_001159"
     CDS             30261..30608
                     /gene="rplV"
                     /locus_tag="ACF3MF_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HFE3927170.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            30622..31278
                     /gene="rpsC"
                     /locus_tag="ACF3MF_001160"
     CDS             30622..31278
                     /gene="rpsC"
                     /locus_tag="ACF3MF_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HFE3927171.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            31281..31715
                     /gene="rplP"
                     /locus_tag="ACF3MF_001161"
     CDS             31281..31715
                     /gene="rplP"
                     /locus_tag="ACF3MF_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011375443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HFE3927172.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            31705..31893
                     /gene="rpmC"
                     /locus_tag="ACF3MF_001162"
     CDS             31705..31893
                     /gene="rpmC"
                     /locus_tag="ACF3MF_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HFE3927173.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            31918..32184
                     /gene="rpsQ"
                     /locus_tag="ACF3MF_001163"
     CDS             31918..32184
                     /gene="rpsQ"
                     /locus_tag="ACF3MF_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HFE3927174.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            32242..32610
                     /gene="rplN"
                     /locus_tag="ACF3MF_001164"
     CDS             32242..32610
                     /gene="rplN"
                     /locus_tag="ACF3MF_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HFE3927175.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            32647..32955
                     /gene="rplX"
                     /locus_tag="ACF3MF_001165"
     CDS             32647..32955
                     /gene="rplX"
                     /locus_tag="ACF3MF_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HFE3927176.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            32983..33522
                     /gene="rplE"
                     /locus_tag="ACF3MF_001166"
     CDS             32983..33522
                     /gene="rplE"
                     /locus_tag="ACF3MF_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HFE3927177.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            33541..33726
                     /locus_tag="ACF3MF_001167"
     CDS             33541..33726
                     /locus_tag="ACF3MF_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HFE3927178.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            33762..34160
                     /gene="rpsH"
                     /locus_tag="ACF3MF_001168"
     CDS             33762..34160
                     /gene="rpsH"
                     /locus_tag="ACF3MF_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HFE3927179.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            34192..34728
                     /gene="rplF"
                     /locus_tag="ACF3MF_001169"
     CDS             34192..34728
                     /gene="rplF"
                     /locus_tag="ACF3MF_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HFE3927180.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            34889..35245
                     /gene="rplR"
                     /locus_tag="ACF3MF_001170"
     CDS             34889..35245
                     /gene="rplR"
                     /locus_tag="ACF3MF_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HFE3927181.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            35266..35766
                     /gene="rpsE"
                     /locus_tag="ACF3MF_001171"
     CDS             35266..35766
                     /gene="rpsE"
                     /locus_tag="ACF3MF_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HFE3927182.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            35781..35960
                     /gene="rpmD"
                     /locus_tag="ACF3MF_001172"
     CDS             35781..35960
                     /gene="rpmD"
                     /locus_tag="ACF3MF_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HFE3927183.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            36004..36444
                     /gene="rplO"
                     /locus_tag="ACF3MF_001173"
     CDS             36004..36444
                     /gene="rplO"
                     /locus_tag="ACF3MF_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HFE3927184.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            36444..37739
                     /gene="secY"
                     /locus_tag="ACF3MF_001174"
     CDS             36444..37739
                     /gene="secY"
                     /locus_tag="ACF3MF_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HFE3927185.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            37801..38448
                     /locus_tag="ACF3MF_001175"
     CDS             37801..38448
                     /locus_tag="ACF3MF_001175"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_function: GO:0019205 - nucleobase-containing compound
                     kinase activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HFE3927186.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            38639..38857
                     /gene="infA"
                     /locus_tag="ACF3MF_001176"
     CDS             38639..38857
                     /gene="infA"
                     /locus_tag="ACF3MF_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HFE3927187.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            38890..39006
                     /gene="rpmJ"
                     /locus_tag="ACF3MF_001177"
     CDS             38890..39006
                     /gene="rpmJ"
                     /locus_tag="ACF3MF_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HFE3927188.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            39024..39389
                     /gene="rpsM"
                     /locus_tag="ACF3MF_001178"
     CDS             39024..39389
                     /gene="rpsM"
                     /locus_tag="ACF3MF_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HFE3927189.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            39417..39806
                     /gene="rpsK"
                     /locus_tag="ACF3MF_001179"
     CDS             39417..39806
                     /gene="rpsK"
                     /locus_tag="ACF3MF_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HFE3927190.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            39886..40824
                     /locus_tag="ACF3MF_001180"
     CDS             39886..40824
                     /locus_tag="ACF3MF_001180"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HFE3927191.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            40852..41232
                     /gene="rplQ"
                     /locus_tag="ACF3MF_001181"
     CDS             40852..41232
                     /gene="rplQ"
                     /locus_tag="ACF3MF_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HFE3927192.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
BASE COUNT        13372 a         7595 c         8848 g        11558 t
ORIGIN      
        1 ggtttatact atagccctgt tagtactcca gcagattttc ggatgcttac tcctattgta
       61 ctggagcaag cctttagaaa agctggaaca gaattgttag agccatatct tagttttaaa
      121 gtttatgcac cacaggaata tctttcacgg gcatataacg atgctcccaa atattgtgca
      181 aatatcgtaa atactcaact gaaaaataat gaggtcatta ttattggaga aattcctgct
      241 cgatgtattc aagattatcg caatgattta acttttttta caaatgggct tagtgtttgt
      301 ttagcagagc taaaaggata tcaggttacc actggcgaac ctgtttgcca gacccgtcgt
      361 ctaaatagtc ggatagataa agtaagatat atgttcaata aaataactta gtgcgtttta
      421 tgttgttata taaatatggt ttcttattaa ataagatgaa atattcttta atatagattt
      481 gaattaaagt ggaaaggagg agattgttat tataaactac aagtggatat tgtgtcctat
      541 ttgtggaaat aaaacaagac tacgaatacg agtggatact atacttaaaa atttcccttt
      601 atactgcccc aaatgtaaga acgaaacttt aattaatgtt caaaaaatga atataataac
      661 aatcaaagag ccagacgcca agacgcagag ccgataattt gagaaatgaa actctcatct
      721 tatcggctct ttttgtttat ctgaatttta ctgactagcc ttcaatattt cttgcttcat
      781 tgataccttt tgctagtgct tccattaagg atagttcttt gtctgtaaag ctatccatgt
      841 atttttctac ctgtaacctt cgagtgcttt taatcaaatt atctgtaggt aagaaaaatt
      901 catcaataga tacatggagt aatgatacaa gatcatacag cacttgtgta cttgggtgtt
      961 gtcctttgtt ttctatattt gttaaataac gtgggtcaat ttcaatcatt gttcccactt
     1021 gttcacgagt gagaccccgt ttcattcgag cctctttaat cgctaaacca acggctctaa
     1081 aatcgtattt atcttctttt ttacgcatac taaatcacct ctatacattt tactgttcct
     1141 atataaccat aaacaggtat agaaaaacat gttatatagt ttatgagttc ctatagaaca
     1201 ctgtggaatt tattaatgcg atgaatccaa tttcaaatag aaaggtcgct gattttattt
     1261 acctatacaa ctttataaaa tttagtcata ctcctagaaa gtagataaaa ttggcgactt
     1321 aatggaggga aaagtcgcca tgagaaagat aatctgtcat ctagttctct taattaagtt
     1381 cttatcaaaa aaacttatcc acctgtactg gatagatatg accatcaatg tggttttgca
     1441 gattacatag atagaaaaat caaagcatat gaacagagaa aacaatctgt ttatgtgctt
     1501 ttttggtcac ttaataaata tcttttagga tttctcttca tttatgcaac aaatcccccg
     1561 ttcgtgtcgg ggtttagtat gaagggagat aaagaagcac atgccactcc ctttcacgac
     1621 agaaaggggg tgaaaagcat gaaaccatct tcttttcaag aaaccataga aaatcagttt
     1681 gactatatct gcaaacaagt tattgaagat gaacgaaaag attacttcaa acatctagac
     1741 agactatcag caaaagaagt ctcgttttct gatatagata actaccttgt caactctttt
     1801 tctactgttg atacgtacgt cactgatttc caactattta aattatttgg attaagaatc
     1861 aatgttgaaa gtgatttatt aagtgaagcc ctgcgtcatc tttcagagaa aaaacggaac
     1921 attattttac ttcattactt tatggatatg agtgatgtgg agattgcgga gttactaaat
     1981 ttgaatcgtt cgactgttta tcgtcatcga ataagtggac tagccatgat taaagaattc
     2041 atgaaggagt gtaaagaatg aaaacagctt atccaagggt tcccttcccc ctcattgtaa
     2101 aggcgacaga tggcgacgtg gaagcaatta atcagattgt taaacattat cgagggtata
     2161 cctcaaaacg ttcattacgt cgcatgacag acgaatatgg aaattctcat atggttattg
     2221 atgaaaccct acgtggcaga atggaaacga aactcatctc taagatttta tcgttcgaaa
     2281 ttaaatagtc ccattttttc gtggaagcgt gtcgaatcgt atccacgctt cccgatttgg
     2341 gaggtttgtt attccatcaa agcatattgt gtgttcagta ggttttgata ggctaacaag
     2401 ccaaacgttc tttgacaacc aaataaaggc aatcgaatac gtttcggtaa gaaaagagct
     2461 gatgaactaa cacgccatga cctacaaaat tagtgagcga ttcatgttag taattcgaaa
     2521 gtaatcttta gcaggattgc tgccatgact ttcttatcgt gataatgata ctcccgtata
     2581 gccatagtcc gagcgttaga agcgtcacag gcaatgggta cggctacatg agaaccatgc
     2641 agaagtgaaa ttcctgtgag ctttgctaga gctgttcgat tgctaagata ttcttctctt
     2701 gtcagtgtat tattataaaa ctatttgata taattatagg tgaatattgg agttttccta
     2761 gcctataatt gggaaaggag taataatgat aacggtcaca aaaaaggatt tagttgagct
     2821 aggatatgga acttcttttt cagcagacat cataaaaaaa gcaaaagaat tgatgattac
     2881 aaaagggcat atctactatc aatctcgaaa gctagataga gtccctcgtg aagctgttga
     2941 agaaattcta ggaattcggt tttcaaatga aaacaggtct gagtagtttt tgcacagtaa
     3001 ggagtaaaaa ctatggttaa agacccaata aaaaaagcaa agaatggaac ctattatttt
     3061 cgtgcaaatc taggttatga ttctaaaggg aaaaaaattc aaaaatatcg tagtggattc
     3121 actactaaaa aagaagcaag agaagaatat tcgaaactgc tattgatgaa accagaagaa
     3181 ttaagtgaga ataaggataa aatgacgttt aaacattata tctttgaaat tttccttcca
     3241 tggtataaga cacaggtaaa gctcagaaca tatgaaaatc gcttaccaac tattaagaag
     3301 catttctctt attttgataa aatggctgtt tccgatattg agcctattga tgtgcaaaat
     3361 tggcaactaa aattatcaaa gaagtgtaag tcttcttatg taagagctgt tcaaggacta
     3421 ttttcagttg ctatggatcg agcaattgtc cttgggataa ccaccacaaa tccatctaag
     3481 attattggca atgtgaaaaa gcaaaagtct aaaattgaat tttggacaaa agaagaattt
     3541 gaaaaagtaa tctctctaat ttacaaagaa gattactatc aacacttttt atttatctct
     3601 ctgtggtttt tatttatgac tggaatgcga attggtgaag ctactgccat tcaatgggaa
     3661 gatattgatt ttgactcagg agtactaacc atcaacaaaa cactctatta caagaatcaa
     3721 tcgaattata gatttgttga accaaaaaca aaggcgagcg ttcgtcatat tgtattagat
     3781 aaatgcacat taacttattt atccgaatgg aaggaagtac aacaaaatct aattcagaca
     3841 gactttgtaa tgagctataa cggtattcct acccaaaaac atacactatc atatgctatt
     3901 gaacgctatg ctaagctggc tggtatccat cgaatcagaa tccatgggtt acggcattct
     3961 catgcttcct tgttaatcag tatgggagaa aatccactta tcattaaaga tcgtctagga
     4021 cacgaagata ttgagacgac tttaggaacg tatggacatc tttatcctaa cagtaatttc
     4081 gaggtagcta acaaattaaa tggagccatt tcctttaaag aagcaaaaca aaattatgat
     4141 acttcaccaa agaatcaatt tactgtagac tacttgcgaa acaaagaaat gaaaaaagtg
     4201 caataaaagt gcagtaaaaa gataagaaga gccagaaacc cttggtataa gaggatttct
     4261 agctctccta caactattcc cactccactg ttgctggtgg tttagaagtg atgtcataca
     4321 cgatacggtt gacgtgggct acttcgttta cgatacgtac agagattttt tgcaagactt
     4381 cccatgggat acgggcaaag tcagcggtca ttccgtcgat tgaagttaca gcacggatac
     4441 cgactgtgta gtcgtaagta cgtccgtcac ccataacacc gacagagcgg atccctggaa
     4501 gaacagtgaa atattgccag atatcacggt caagtccagc agctgcgatt tcttcacgca
     4561 agatagcatc agattcgcgt acgatttcta gcttgtcttc agtgatttcg ccaagaacac
     4621 gaataccaag accaggacca gggaatggct gacgccaaac gattgaatca ggcatgccta
     4681 actgagtccc taattcacgg acttcgtctt tgaataatgt gtttaatggt tcgatcaatt
     4741 caaattgcat atcttctggc agtccaccta cattatggtg agatttgatc gtctgtgctg
     4801 tttctgtacc agattcgata acgtcagtat acaacgttcc ttgtgctagg aaagagacgc
     4861 cttcttcacc agcaagtttt gttgcttcgt catcaaaaac atatacgaat tcattcccaa
     4921 tgattttacg tttttgttct gggtcagata cacctttcaa cttgtctaag aagcgatctc
     4981 ttgcatcgac tttgatgatg ttcaagccga attttccgcc tagactttcc attacttgtt
     5041 ccgcttcgcc tttgcgtagc agaccgtggt caacaaagat agatgtcaat tggtcaccga
     5101 tcgctttttg taaaagaacc ccaacgacac tagaatcaac gccacctgaa agaccaagca
     5161 agactttttt gtcaccaact tgttcacgga ttttttctac ttgcatatcg ataaagttat
     5221 ccattgtcca gttaccttca cagtgacaaa catcaaaggc aaagtggcgc agcaattcga
     5281 ttccgtattc ggaatgacgt acttctgcat ggaattggat accataaaaa ttacgtgttg
     5341 tgtcttggat agaagcaatc ggacaatctt tgcttgttcc gactgtttca aagccttcag
     5401 gaactttagt taccaagtca ccatggctca tccatactgt ttgttgtttt ggtgtttctt
     5461 taaacaagac agcttgatcg cttgttactt ctaacaaggc tttcccatat tcgcggtttt
     5521 tagcaggctc tacggaaccg ccaagtttgt acgtgatcaa ttgcatacca tagcaaatcc
     5581 ctaatacagg aatacctaaa ttgaagatct caggatcgat cccaaatgca ttctcatcat
     5641 atacactgtt tggtccgcca gaaagaatga ttccctttgg attcatcgct tttacttctt
     5701 ctgcagtaat gcggtggctc aataattcgg aaaagactcc aagatcacga atacgtcttg
     5761 tgatcaattg gttatactga ctaccgtagt ctaatacgat aatcttttca acgttcgtca
     5821 tatcggcaac gtttgtcaaa tttattaccc ctatcccttt aaattttatc tcaaaatagt
     5881 caaactattt taaaatgcta atattttcgc atgaaaatcg aatcgatgat atgattttca
     5941 gttttatgga gaattatatc ggctcttcct cgtgtaggca agatatattc ctgtaaattt
     6001 ttcaaattca catttttcca tacatctttt gccattttaa aggcttcttc acgatctccg
     6061 atagcaaaac gataataata attctctgga ttttggaaag ccgtatccag taacgcacca
     6121 aaacgatcca aataccattt ttcgatcagc acgggatcgg catcgacata gacagaaaaa
     6181 tcaaaaaagt cgctgacgta gatttgctga ttcgcaggta attgaagcgt attgatcccc
     6241 tcaacgatca agatatcagg ctgctggatc aattcgtact tgtctggaat gatatcatac
     6301 acatcatgtg agtaaacagg tacttttatc tcttcctgac cagattttac acggttcaag
     6361 aaatcgatca gcatctccat atcataactt tcaggaaatc ctttacggtc catgattcca
     6421 cgctctttta atatacgatt tggataaaga aatccgtcag tcgtgatcag ctgaacgttt
     6481 cttcgtttga aggtacgaga caaaatcgtc tgcagcagtc tggctgttgt actttttcca
     6541 acggctacac ttccggcgat cccgataata aaaggcggta cttctacgta tttatgaaga
     6601 aataaacctt tactcaagaa caaagattca aattctttca tataaagata aatcagatga
     6661 gcaagaggta catagatatc tcgaacatcc tgcatggaaa tgcggtcatt caaacttttg
     6721 atattatcta gttcatcttg tgtcaaaggt gcttgcccat tacgataaaa ttctcgccat
     6781 tcttctcttg ccacacggta gtagttcatt ggatcattca tattagcctc ctgcgttctc
     6841 ccatcaatgg aactatttta acacaaaata aacgcaaacc ccaccactta agagagattg
     6901 ccgatctttt tgtataatct ttataataga aagaaacgga gtcttattct tgacttgcgc
     6961 acggatacat aaaaggatag actgttgtca tgaaagaaat gagaaggatg gaagacatga
     7021 caaatcatta ctattctgaa cgcccagata cggcgcacga ttttgaacaa tgggcttttg
     7081 agttaaaagg cagaaccttt caatttgtaa cagattctgg tgtattttca cgtgaaacag
     7141 tggattatgg ttcacgtgtc ctgattgatg ctttcgattg ggaagagtta cctgatgaag
     7201 gaaagatctt agatgtggga tgcgggtatg gaccgattgg gttagctttg gcatttgcga
     7261 cacagcggtt tgttgaaatg gtcgacatta atgaacgagc ggtaagtcta gcgcaaggaa
     7321 acgcaaagcg taaccaaatc gaacatgttg atatccatca atcgaatatc tatgaagcag
     7381 ttcatgaaga aacctatgca gctatcgtaa gcaatccgcc gatccgtgct ggaaaaaaag
     7441 ttgtacatga aattttgaca ggcgcatatc ctcggttgaa gaagggcggt acactgacaa
     7501 ttgtgatcca gaagaaacaa ggagcgccga gtgcgcaaaa gaaaatggaa gaaacatttg
     7561 gtaatgcaga aatcgtcaca aaagataaag gatattatat catcaaaagt gtgaaagaat
     7621 aactagctga aaaatagtgg agcgacgaaa gagtggaact gggcgtgcat gtacgggtac
     7681 gtatcagttc tttttttgtt gagaagtttt taaaaacaaa gaactatttt ttcttcaaaa
     7741 agaaatagta ggaacagagt cgttgttttt tacgataaaa taaataagat acagaacttg
     7801 tatagaaggc tgccaagtcg gtagataaag gaggttttta tcaaaaaaca tactttcctt
     7861 ttttctctat tcttttcttg ggggttttgg tacactgata gggaatttag atagaaggga
     7921 gccaatagga tgaagctgac catcagagat atcgcagaaa tggcaggcgt atcagtaaca
     7981 actgtctcac agattttgaa taacaaagga agcagattta gtgataagac aagaaaaaaa
     8041 gtgttgtcga tcgtgaatga acatcattat aagcccgatt atttcgcttc aaatgtgatc
     8101 aatcgacatt caaagaccat cggaatgatc gtccctgatg tcactgattt cttcttctcc
     8161 aaactgatcg aaggtgtaga gagctatttg aatcctttgg gctatgtgat catgttatgc
     8221 aattctcgtc atagccaaga aaatgagatc aagtatttac aagagctttc ccaccgctca
     8281 gtggacggaa tcttgctggc cacaccaaat attttacctg agaaatatgc attagacagc
     8341 ggtttttatc aaaaaatgcc aatcatttta atcgatcgcg gattgaatcg tcgggataac
     8401 ggacggctta tcgtaaagga atatgagggc gcctatcaag ctgtttcgct gtttattgaa
     8461 aatggccata cgaagatcgg catgctgaag gaaaccactg gatactatca attagaagaa
     8521 cgtttcaacg gatatcgtca tgcgctgaaa gatcatggcc tgccttttaa tgggaaattt
     8581 gttgaacatg gagagttgac tgtccaaggt ggatatactg catcaaaaaa attactcaaa
     8641 cataaagata tcacggctat tttttgcggg aatgatgcca tggcgatcgg atgctatcag
     8701 gcgatcgatg aattgggcaa aaaaatccca gaagatatct cagtcatagg attcgatgga
     8761 ttaaagctgt cagaatacat gattccgcaa ttgacgacag tgcagcagcc aagttttgat
     8821 attggatttt atgctgcacg tttcctgatc gatacgatcg aatttcctca aagaaaagtt
     8881 ccgaacaaag tgttcgaaac aaaattaatt attcgtgaga gcgtaaaagt attgacaaag
     8941 ggctaactcg gcggtatatt gcttatgtaa gcatttacaa aggctagtta gtgctttttt
     9001 tatttttagt aaaccagttt actaaagtgg tttacctttc ctaaaaataa tgtataatac
     9061 cgaatgaaga caaggaggat caggcaatgc gaatggtgga tctgattgaa aaaaagaggg
     9121 atggaaacga gctgtcgaaa gaggaaatcg agtacatcgt cacgaactat acgaatggaa
     9181 agattccaga ttatcaagtc agtgcattat tgatggcaat tttttatcaa gacatgacaa
     9241 atgaagaaat cacgaactta acattggcga ttgctaattc tggtgatgtc atcgatttga
     9301 gttctcttga aggaataaag gtagataagc attcgacagg tggcgttggt gacacgacca
     9361 cattgatttt agccccccta gtagctagtg tcggagtgac agtggctaaa atgtctggac
     9421 gcggtctagg ttacacaggt ggtacactag acaagctaga agcaattccc ggatttcaga
     9481 tcgagctttc ggatgaagaa tttgtacgca ttgttaatga aagtaaagta gcggtaattg
     9541 gtcaatcagg aaacttggca ccggcggaca aaaaattgta tgccttgcgt gacgtcacag
     9601 cgaccgttga ttctcttccg ctgattgcca gttcgattat gagtaaaaaa atcgcggcag
     9661 gagcagatgc aatcgttttg gatgtgacca ctggagacgg tgctttcatg aagaacatcg
     9721 aagatgcaag acgtctggca aagaccatga cgagcattgg gaaactggct aaccgagaaa
     9781 cagtggcggt tatctcagat atgtcagaac ctcttggcga agctatcgga aatagtctag
     9841 aagttgtcga ggcaatcgaa acattacaag gaaatggtcc agaagatcta gtagaaatgt
     9901 gctacgcctt aggaagccaa atggttgttc ttgctggcaa agctaagaca accgatgaag
     9961 caagaacgtt gcttcaagaa gctctggaat caggtaaagc gttagcaaaa ttcaaagaaa
    10021 tgatccaaaa tcaaggggga gacccagcga tcgtggaaca tccagaacga attttgactg
    10081 cacgctacac aatggagctt cctgctaaac aaagcggagt tgtgtcaaaa atcgtggcaa
    10141 atgaattagg aattgctgca atgatgctag gtgctgggcg taaaaccaaa gaagaagata
    10201 ttgatcacgc tgttggattg aaactgcata aaaaaattgg tgacactgtg acaaaaggtg
    10261 agtcactatt gacgatctat agtaacgacg aagaaatcac ttctgtcatt gaattattat
    10321 ataaaaatat tgaaattggt gaatcggcaa tgaagccaac gttgattcat gacatcatca
    10381 cagaataaag gaaaaaagcg gactttaccg ttttaaagaa aaggggaaaa gaaatggaac
    10441 taaaccgaat gatcgaccat actattttga aagcagacgc atctaaagaa gctgtgatgc
    10501 aaattatcga agaagcaaaa aaataccatt tttattctgt ctgcatcaat ccagcatggg
    10561 ttgcgctagc gaaagaacaa ttacaaggtg agccagtagc cgtatgtaca gtaatcgggt
    10621 ttcctctagg agcaaacaca cccgagacaa aagcatttga aacaacagat gccatcaata
    10681 acggtgcaga tgaagtcgat atggtcatca atatcggtgc tttgaaatca aaggatgatc
    10741 aacaagtcca aaaagatatc gaagcagttg ttgaagcagc aaaagatcgt gcgcttgtca
    10801 aagttattat tgaaacatcg ttattagata gagaagaaat catccgagct tgcgaaatag
    10861 caaaagctgc aggcgctgat tttgtcaaaa catcaactgg tttctcaaca ggcggagcaa
    10921 aggtagagga tgtccgtttg atgcgtgaaa ctgtaggacc agaaatgggt gtcaaagctt
    10981 ccggcggtat ccataacgaa gaagaagcaa tggcaatgat cgaagctggt gctacaagaa
    11041 tcggaacaag cgcaggagta gcaatcgtat ctggttcaac tggtgaaggc tattaatttt
    11101 ttcaaaggag aagctcatgg cagaactcaa acaagaatgg atcaacacag ctattgaagc
    11161 gttagataaa gcctatgttc cttattccca ttttccggta ggcgcttgtc tcgtaacgga
    11221 atcaggcaag atttatcaag gcatcaacat tgagaatgca tcatttggat taacgaattg
    11281 tgccgagcgc acagcttttt tcaaagcagt atctgaagga gaaaaaacat ttacgcatct
    11341 agtcgtagcg gggcacaccc ccgatcctat ctctccttgt ggtgcatgtc gacaagtaat
    11401 ggcagaattc tgttcccctg atatgccggt tacgctagta ggagacaatg gtgtgacgaa
    11461 ggcaacgacc gttcgtgcac tgctgcctta tgcatttact gaaaaagatc tataactcat
    11521 gttcattcag tcagctgact gttgaaaaat aaaacaatta ttttaggagg ctttacagaa
    11581 atgaaaaaag caaaattatt tggtttaggt gctgtcgcac tagcagcagg gttattttta
    11641 ggtgcatgcg gcaacaacgg ctctactgat tcatccggtg gcaaaagctc atcagacaca
    11701 acaactgcag cattgatcac agacacaggt ggtgtagacg accgttcatt caaccagtca
    11761 gcttgggaag gactagaaaa atgggggaaa gatcaaggac tttcacgagg aaatgatggc
    11821 ttccaatatt tccaatcttc aaatgaatca gattacatcc caaatattga ccaagcattg
    11881 aatgctggat tcaaaacgat ttttggtatt ggttataaac taaaaccagc gatccaagaa
    11941 caagcaacaa acaatacagg tacgaacttt gttattatcg atgatgtcat cgatggatta
    12001 gataacgttg tatctgcaac tttcaaagac aacgaagctt cttatcttgc aggtgttgca
    12061 gcagcttata cgactgaaac aaacgtagtc ggctttatcg gcggtgtaaa aggtgaagta
    12121 atcgatcgtt ttgatgctgg attcaaagcc ggtgttgatg caggtgcgaa agaattagga
    12181 aaagaaatca aagtattgaa tcaatatgct ggtgacttct ctgctccaga taaaggacgt
    12241 tcaattgctc aaggtatgta tgcacaaaac gcagatatca tcttccatgc ttcaggcggt
    12301 acaggtaacg gtgtattcca agaagcaaaa tcattgaacg aatcaggcga caaaaaagtt
    12361 tgggttatcg gtgttgaccg cgaccaatca gacgaaggcg aatacacatt aaacggcgaa
    12421 aagaaaaact tcacattgac atctacactg aaagcagttg gaacagtagt agaagatttg
    12481 gcacaaaaat cagcggacgg taaattccct ggcggcgaac acactgttta tggattgaaa
    12541 gaagacggtg ttggtctaac agaaggacaa ctttctgacg aagcgaaaaa agcagttgat
    12601 gaagcaaaag aaaaaatcat ttcaggtgac gtaaaagttc cagaaactcc tgaagaaaac
    12661 taaaaccatt tctatagcct tgttagacac atgtttgaca aggctatggt ttgattagaa
    12721 caagaattgt tcatttatcc aagctgcctt gtgacagttt ggataaggga acaactccct
    12781 gaagtaatgt ttgtttcaaa agaagaacgc tcactaagcg tgaatcttag tcaatcgttg
    12841 ccctagatag aaatcgttag gatgtgaaaa aaaggtggtt caagaaaata ttgtcataga
    12901 aatgcagaat attaccaaag aatttggaac attcaaggca aatgacaaca tcaatttaca
    12961 agtaaaggca ggagaaattc atgcgttgct tggagaaaac ggtgctggca aatctacatt
    13021 gatgaacgtg ctttccggat tattagagcc gacatcaggg aaaattttga tgcgtgggaa
    13081 agaagtaaag atcacaagtc cgaccaaagc caaccaatta gggattggga tggtccatca
    13141 gcactttatg cttgttgatg cctttactgt aacagaaaac atcgtgttgg gaagcgagcc
    13201 tagtcgcgca gggatgcttg accataaaaa agcacgaaaa gagatccaaa aagtttctga
    13261 acagtatgga ttgtcagtca acccagatgc ttacgttcgt gatatttcag ttggaatgga
    13321 acaacgggta gaaattttaa aaacacttta ccgaggagca gatgtactga tttttgatga
    13381 gccgacagct gtattgaccc ctcaagaaat tgatgaatta atcgtgatca tgaaggaatt
    13441 agtcaaagaa ggcaagtcga tcattttgat tacgcataag ttagatgaaa tcaaagcagt
    13501 agctgaccgc tgtacagtta tccgccgtgg aaaaggaatc ggtacagtca acgttaaaga
    13561 cgtaacctca caacaattag ccgatatgat ggttggaaga acggtttcat tcaaaacgat
    13621 gaaaaaagaa gcgaagcctc aagaagtcgt tttgtctatt gaaaatctag tggtgaaaga
    13681 aaatcgtgga ttagaagccg tgaaaaactt gaacttagag gttcgtgctg gcgaagtact
    13741 tggtatcgct ggaatcgatg gaaacgggca gtcggagttg atccaagctt tgactggttt
    13801 gcgaaaggca gaaagcggac atatcaagct aaaaggggaa gacatcacta ataaaaaacc
    13861 ccgaaaaatc actgaacatg gtgtaggaca cgtgccagaa gaccgtcata aatacgggtt
    13921 agtcctagat atgacattat ctgaaaatat cgcactacaa acctatcatc aaaaacctta
    13981 cagtaaaaac ggcatgctga attattcagt aatgaatgaa catgccagag aattgatcga
    14041 agaatatgat gttcgaacaa cgaatgaact tgttcccgca aaagctttat caggcggaaa
    14101 tcagcaaaaa gcaattatcg ctcgtgaagt cgaccgagat cctgatctgt tgattgttgc
    14161 aaatccaact cgtggactgg atgtaggtgc gatcgaattt attcataaac gtctgatcga
    14221 acaaagggac aaatacaaag cagtgttact gatcagtttc gaattagaag aaattttaaa
    14281 tgtttcggat cgtattgctg ttatccatga aggagaaatt gtcggtatcg ttgatccgaa
    14341 agaaacatct gaaaatgaat taggtctatt gatggcgggc tataccttag aagaagcacg
    14401 aaaagagtta gaaaaggggg ctggcgcaca tgaatgatcg cagcgaaaaa ttccgtaatt
    14461 tattagtgcc tgtactttca gttgttttag gattgatctt aggcgcgata ttgatggctg
    14521 cttttggttt tcagcccatc caaggttatt cttctatgct agatgcagcc cttggttcgc
    14581 aaagagggat aggtgaaacg ttaaggcaag caacgccgtt gatttttaca gcattaggtt
    14641 tttctgtagc taactcagct gggtttttca atattgggct ttctggacaa gcactttgcg
    14701 ggtggatcgt cagtgtctgg gtggcacttg cgtttccaga tctgccaaaa gttgttttgc
    14761 ttccgttatg cgtgatctta ggtgccttag ctggtgcgat ggcagcggct gttccaggtt
    14821 tacttcgagc attttttgga acaagtgaag tgatcgtaac aatcatgatg aactatatct
    14881 tattatacgt aagcacattt gctttacatg aagtgatgcc tgaaagctat cgctcaagtt
    14941 tggactcttc caatatgatc agtcaaaatg cctcactgcg gttaccatgg ttaacacaag
    15001 cttttggcgg ctctcgcgta aactcaggat tatttttagc aatcatcgcg cttattttcg
    15061 tttggctgct gatgaagaaa acgactttag gatttgaaat ccgttctgtt ggattgaatc
    15121 cttttgcttc tgagtatgca ggaatgagta gtaaacgtac gatcgttttg tcgatggtca
    15181 tttctggcgc tttggcaggg cttggcggtg tggttgaagg attaggaacg tatcaaaact
    15241 tctttgttca aacgacttcg ctatctattg gatttgacgg aatggctgtt tccttgcttg
    15301 gttctggatc agcaatcggt attcttttat cagcgatctt gttcagtatt ttgaagatcg
    15361 gtggacttgg catgcagaca ggagcaggtg ttccgtttga gatcgtcaat gtatcgattg
    15421 ctttgattat cttctttgtc gggatcaact tcctgattcg tttcgtcatg gctaaagtct
    15481 tccaagggaa aaaacaagaa gagatcgttg cgacaataga atcgaaacca acgaatcaaa
    15541 accatgaagg gggcgaacta taatgtcgac tatcgaatta attgccttga tccttacttc
    15601 tacactggtt tattcaacac cgctaattct aacgtcacta ggcggaactt tttctgaacg
    15661 aagcgggatc gtaaacgtag ggctagaggg aatcatggtc atgggtgctt ttagttccat
    15721 cgttttcaac ttgacgatga gtccatcact tggttctatg acaccatgga tcgctatttt
    15781 agtgggtggc gtcgtaggta tcctattttc tctgattcac gcagtagcaa cagtcagttt
    15841 gcgtgctgac catattatca gcgggacagt aattaatctg atggcacctg ctttaggtgt
    15901 tttcttgatc aaagcatggt atggtaaagg tcaaactgat aacatcacgc agaatctggg
    15961 gtatttttct ttcccaggat tagcagatat tccggtcatt ggaccaattt tctttaaaaa
    16021 tacattctta cctgcttatt gtgctatttt gattgctgtc ctagcttggg tgatcatctt
    16081 caagacgaaa ttcggcttgc gcctccgttc agttggtgaa aatcctcaag ctgccgacac
    16141 attaggtatc aatgtatatg ctatgcgtta ttcaggcgta ctgatttctg gcttgttagg
    16201 cggtatgggc ggtgctgttt ttgctcagtc gatttccggt aacttttcag ctggtacgat
    16261 cgttggacaa gggttcatct ccatggctgc tatgatcttt ggtaagtgga atcctttagg
    16321 ggcaatgggt gcctcattgt tctttggttt tgctcaaagc ttgagtatca ttggcgcaca
    16381 attaccagtt atttcttcga ttccgccagt attgctgcaa attgctccat atttgctgac
    16441 aatcattgtg ctggttgttt tcttagggaa agcttctggt ccaaaagcaa acgggaagaa
    16501 ctatatcaaa tcaaaataat cttttagcga ataaaaaggg tgggttacgg gaagtgtttt
    16561 tcgtctcgcc ctttttgttt taaaggcaat aaaaataaaa agaaagaagg aataatcatg
    16621 tttaaacgcg tacatctgat cgtcatggat tcagtaggaa ttggagaagc accagatgcc
    16681 gataagttcg gtgatgttgg ttctgataca ttaggacaca ttgcgaaaga agcaggattg
    16741 aacgttccac atttagagca gcttggttta ggaacgatcc gtcctcttga aggtgtggaa
    16801 tcagtgaaag atcatcaagg ctatgcgacg aaattagaag aagtttctgt agggaaagat
    16861 acgatgacag gccactggga aatcatggga ttgaatatca aaactccatt tcgtgtgttt
    16921 cctaatggat tccctgatga tctgatcaaa caaatcgaag aattttctgg ccgtaaagtc
    16981 gtatgtaaca aaccttatag cggaacagct gttattgacg attacggtga acaccaaatg
    17041 aaaacaggcg atttaattgt atatacttct gccgatcctg tccttcagat cgcggcacat
    17101 gaagaaatca ttcctttaga agaattatat cggatttgcc aattcgttcg tgatataaca
    17161 aaagatgatc cgtatatgat tggccgaatc attgcacgtc cgtacgtggg tgaaccagga
    17221 gacttcacac gaacaagcaa tcgccatgat tatgcgttga atccattcgg acacacagtc
    17281 cttgattctt tgaaagaagc aggaaaggac gtgattgctg ttggaaagat caacgatatt
    17341 ttcaacggac aaggaatcac tgaatctgtc cgcacgaaaa gcaatatgga tggcgttgac
    17401 cagctgctga aagttatgaa aaacgatttt tcaggaatca gctttaccaa tttagtagat
    17461 tttgatgcat tatacggtca tcgtcgggat gtagtcggct atgcgcatgc gattgaagaa
    17521 tttgacttac gaattccaga attgcttgaa gcgatggaag aagacgactt gctaatgatt
    17581 acagccgatc acggaaacga tccgacgttt actggtaccg atcatacgcg agaatatgta
    17641 ccgttattgg tttacagtaa aaaaatgaaa gaacaagggg cattgcctca aggatattat
    17701 tcagatattt cagcaacgat tgctgagaac tttagtgttt cttcgactga aaatggcgaa
    17761 agcttcttga aattattaaa ataatctttt taaataggag aaagcaaatg accaagttaa
    17821 gcgagatgtt acaagaaacg acccagttta tccttgataa aggagtaaaa gaaattgatt
    17881 ttggtttgat tctaggttca ggattaggtg aattagcaga tgaaatcgaa gatgctgtaa
    17941 tgatttctta tgatgagatc ccgttctttc ctgtttcgac agtagttggg catgcaggaa
    18001 agctagttta tgggtctctg gcaggcaaga aagtgttagc catgcaaggg agattccact
    18061 actatgaagg tcattccatg caaacagtga cctatccagt acgtgtgatg gccggactag
    18121 gggcccattc agtcattgtg actaatgcat gtggtggtgt caacgaatca tttgtaccag
    18181 gagatttgat gctgattacc gatcatatca attttactgg tgaaaatcct ttgatcggtc
    18241 cgaatgaaga tgcaatgggc cctagatttc cagatatgag tcaagcttat acgcctgact
    18301 atcaagcaac agcaaaagca gcagcagaaa aactaggttt ggatcttaaa gaaggcgtat
    18361 atatgggcta ttctggacca acttatgaaa cgcctgcgga gatccgaatg tctcggacaa
    18421 taggagccga tgcagtaggg atgtcgactg ttccagaagt catcgtagca gctcacagcg
    18481 gattaaaagt gttaggaatc tcttgtatta ccaacttagc agcaggtatg caagcgaatc
    18541 tgagccatga agaagttgta gaaacaactc agagagtcaa acaatctttt aaagcattgg
    18601 ttaaagaaac attgacatta ttgtaatagg aggaacaata aaatgagtgt gcatattgaa
    18661 gcgaaagaag gcgagatcgc cgataagatt ttacttccgg gagatccttt gcgagctaaa
    18721 tatattgcgg agactttttt ggaagatcca gtttgttaca atcaggtacg cggtatgtta
    18781 ggctttaccg gcaaatataa aggagaacgt atttctgttc aaggaacagg aatgggaatg
    18841 ccatcagcca ccatctatgc ccatgaattg atccagtcgt atggtgtaaa gaaattgatt
    18901 cgagtaggta catgcggtgc attgtcaaaa gacgtccatg ttcgtgattt agtactagca
    18961 caaggtgcag cgaccagttc ttcgatgatc gaaaaaaatt tccaagcctt tcattttcct
    19021 ccaatcagtg atttcaatct attactgaaa gcatatgaga tagctaaaga aaagggctat
    19081 acggttcatg taggaaatgt tctttcggaa gattctttct acaaagatga tttgacagag
    19141 acgttccaat tagctgaact tggcgtttta ggagtggaaa tggaagcagc ggctctttat
    19201 tacttaggcg cgaaatacca tgtgcagaca ttaagtttga tgaccgttag cgaccatttg
    19261 atcaccggtg aagaaacaac agctgcagaa cgtcaatcta cgttcaatga aatgatcgaa
    19321 gtaggattgg aaacagcgat agcagaataa gaaggaaatg aaaaagctgc cctgcattaa
    19381 gtaataagaa catccaagca aaaatagctc ctcatgtttt tgacttggct ggacttatta
    19441 ttgcaaatgt aagcttttga acaccgttta ccaagaggtt gtgaatctgc cgtttaactc
    19501 tgagtcacaa ggaacaattt caaaaaacag cttttcatgt ttgatgaata ttgtgacttg
    19561 tgaccgagaa gttggcagga gaaaaccgtt tatacgaaaa aagggactgt gacaaatcgt
    19621 gtcacagtcc cttttttata gtgtttttta taggtagtat tttttagcaa ctgttaagtc
    19681 atcatttaat tcataaacaa gtggttgacc tgttggaatt tcaagatcca tgatgtcttc
    19741 gtcagagata ccttcgatat gtttagctag ggcgcgtaat gagttaccat gtgcagctac
    19801 taaaacagtt ttgttgtcta gtaatgctgg agcaatttca tcttgccaga atggcaaagc
    19861 gcgttctaat gtcactttca agttttctcc accaggaata tcgcgtttgt ctaacattgc
    19921 gtaacgacgg tcatttgctg cagaaccttc gtcagtttct tccattaatg gaggaagagt
    19981 atcgtaagaa cgacgccaga tgtgcacttg ttcgtcgccg tatttttcag ctgtttcttt
    20041 tttgttcaaa ccttgtaatt taccatagtg acgttcgttt aagcgccatg atttgatttg
    20101 tggtacccaa agttgatctg aatattctaa gatcaagtta catgttttga ttgcacgagt
    20161 taaaacagaa gtgtaagcaa catcaaattc gattccagct tctttgattt tgcgtccgcc
    20221 ttcttttgct tcttcgattc cttctggtgc tagatttaca tcagcccaac cagtaaattg
    20281 gttcaatgca ttccattcac taagaccgtg acgagaaaaa actaattttg gcatgtttag
    20341 ctctcctttt aagataggtt tatatttctg aaattttcag ttctgtttta ttgtacaatt
    20401 ttttggaaga gatttccatc gaaaaattag ataagattct atgagaaaac aagtagagaa
    20461 tataaaaaaa cgaacagtgc ccacgcaact gttcgttttt aggtattaga tgcataattg
    20521 ctcgatttct ttttcaggta aattgatata tttataacat gttccaactg aaacaccgca
    20581 ttttgaagaa ataaattgga tcgtttcttt tttttcataa tagagacgtc ggattttttt
    20641 gatcgttttt gcatcgattt ttggtcttcc gccgattttt ccttttttac gagcttcatc
    20701 taatccaact aatgtacgtt ctttgatcaa tgcgcactcc atgtttgcta ggttttccat
    20761 taattggaaa tagatttttc ccatttcgcg cgtatcgatt ccttcatcaa gactaatcaa
    20821 gtgcagcccg cgatctttga ataattgcgt gagttctgtt aattgccgcg tagatttgcc
    20881 taatcgatga agttggcaaa tgactagtgc atcgccttgt tgcatgtcag cgatcactga
    20941 ctccaaatga acagcagtag aatcattttg ttccacttca tatgtctcat ggaaaatttc
    21001 ttgacaacca aagtcagata attgatcaac ctgagttgtt aaatcaacgt catttatggt
    21061 tgtgcgtgca taaccaataa ttttcatggt gattcctttc tagcagtgat tttctaactg
    21121 gatataacag taaaaatgta gcataaagta cgtcaaaaag atagtttttt cgcaaatttt
    21181 ccgctgtctt tttttattgg atgatcaagc agtttttctt tatttacgac ggattgcgtc
    21241 aagaatctca acgccttttt ctgagccgac aactacttta gaaaccatgt ttaggaaaag
    21301 cccatgttct actaccccaa caagttcatc taaataggta gctaagcttt ctggctgttc
    21361 gatgacttct agatgcagat caatgatgta atgaccacca tctgtggtta agacttctcc
    21421 gttttcgtct gtacgcaaga cgggttggaa tcttttttct tcaaaaatat gaagtagctg
    21481 ttgggagcca taagggatca cttcaactgg gagtgggaac ttcccaagtt tatcgactaa
    21541 tttagaagaa tcaacgatcc aaatcgtttc ttttgagtac gtagcgacta ttttctcgaa
    21601 aagcaaagca gcgccgccgc ctttgatccc ttgaaaatca gcactgattt catcagcacc
    21661 gtctattgtc aaatcgacta cggggacttc atcaatactc tttaacggta ttcctaattt
    21721 ttccgcttgt tcttttgtcg catttgaagt agtaactcct gtgatacgta aaccttcttc
    21781 acgcatacgg cgaccaatct cttctaccat ataataggcg gttgaaccgg tcccgagacc
    21841 tacgatcatc ccgtccttta cgaatttcgc ggcttcaatg ccagctaatt gttttaaatt
    21901 catctttgcg tccacctttt tttagtttga gcatcgtgct ttcctcacta ttttagcgtg
    21961 atttacggta aaaagatacc attctttttt attccaataa agctttttca aaaaaaattg
    22021 catctcttgt tgacatgttt tttcattcgt gatattctaa caaaggtgct ttatctacag
    22081 gtttctgtga agaaacgtgc tgactgttta tcaaagcata tttgataagg atgcagacat
    22141 tgcatttatt ttttatcaca aaaaaagaac cacctggatg tgtggaacta gacgcaaatc
    22201 gtgggaagga ggaaacaagg aatgcctaca attaaccaat tagtacgtaa acctcgtaaa
    22261 tcaaaggtgg aaaaatctaa ttcacctgct ttgaacaaag gatataacag ctttaagaaa
    22321 actcaaacta acgtaaactc acctcaaaaa cgtggggtag caactcgtgt gggtacaatg
    22381 acacctaaaa aaccgaactc agctttacgt aaatatgcac gtgttcgttt gtcaaactta
    22441 attgaagtta ctgcttatat cccagggatt ggtcataact tacaagaaca cagtgttgta
    22501 ttattacgcg gtggtcgtgt aaaagactta ccaggggtac gttaccatat cgttcgcggt
    22561 gctttagata ctgctggtgt taacgaccgt aaacaaagcc gttctaaata cggaactaaa
    22621 aaacctaaag cttaatttta attattaaac aaatgaaact tgcttctact atatagaagt
    22681 aattactatg aacaatattt cggaaggagg agttacggat gccacgtaaa ggtcctgttg
    22741 caaaacgtga tgttttacca gatcctattt ataactcaaa attagtaact cgcttgatca
    22801 accgtgtaat ggttgacgga aaacgcggga ttgcagctaa cattatctat aatgcctttg
    22861 acttgatcaa agaatctaca ggtaacgatc cattagaagt gtttgaacaa gcaatgaaaa
    22921 acgttcaacc tgttcttgaa gttaaagcac gtcgtgttgg gggttcaaac taccaagtac
    22981 cagttgaagt tcgccctgaa cgccgcgtta ctctaggtct tcgttgggta gtaaactacg
    23041 ctcgcttgcg cggtgaacac acaatggaag aacgcttagc aaaagaaatc atggatgctg
    23101 caaacaacac aggtgcttct gttaaaaaac gtgaagacac tcataaaatg gctgatgcca
    23161 accgtgcgtt tgctcactat cgctggtaag attctctctg tttggtcggc ttttataagt
    23221 cgacctcaga tagtgtcctt atttttagca actagatagt aaagagagga gaaacaagga
    23281 gaatgaccag agaattttct ttacaaaaca ctcgtaatat cggtatcatg gcccacatcg
    23341 atgctggtaa aacgactgct actgaacgta tcttgtacta tactggtaaa atccataaaa
    23401 ttggtgaaac tcatgaagga gcttcacaaa tggactggat ggaacaagaa caagaacgtg
    23461 gtattacgat cacttctgct gctactacag cacaatggaa gggtcaccga atcaacatca
    23521 tcgacacacc aggacacgta gacttcacag ttgaagttga acgttcattg cgtgtacttg
    23581 atggtgctgt aactgttctt gatgcacaat caggtgttga acctcaaact gaaacagttt
    23641 ggcgtcaagc aacaacttat ggtgtacctc gtatcgtatt tgcaaacaaa atggacaaga
    23701 tcggtgctga cttcttatat tcagtatcaa ctttacatga ccgtttgcaa gcaaacgctc
    23761 acccaatcca attaccaatt ggtgcggaag acgacttcac aggaattatc gaccttgtaa
    23821 caatgaaggc tgaaatgtat acaaacgatc ttggaacaga gatcgaagaa acagaaattc
    23881 ctgaagaata ccgcgaatta gctgaagaat ggcgcgaaaa attggttgaa gctgtagctg
    23941 aaactgatga agaacttact ttgaaatact tagaaggtga agaaatcact gaagctgagt
    24001 taaaagaagg tatccgccgc gcaacagtta acgtagaatt ctacccagta ctatgtggtt
    24061 cagcatttaa gaacaaaggg gttcaattac tattggacgc tgttcttgat tacttgccat
    24121 caccgttaga tatcccagct atcaaaggga ttgaccctaa aactgatgaa gaagtagaac
    24181 gtcctgcaga cgacagcgct cctttctcag ctttagcatt taaagttatg actgacccat
    24241 tcgtaggtcg tttaactttc ttccgtgtgt actctggtgt tttacaatca ggttcatacg
    24301 tacaaaacgc aacaaaaggc aaacgtgaac gtgttggtcg tatcctacag atgcatgcca
    24361 actctcgttc agaaatctct gaagtttacg ctggagatat cgctgctgct gttggtttga
    24421 aagacacaac tactggggac acactatgtg atgaaaagag tctagttatt cttgaatcca
    24481 tggaattccc agaaccagtt atccaagtcg ctattgaacc taaatcaaaa gctgaccaag
    24541 ataaaatggg tgtggcttta caaaaactat ctgaagaaga tcctactttc cgtgctgaaa
    24601 caaacgtgga aacaggcgaa acaatcatcg ctggtatggg tgaacttcac ttagatatca
    24661 tcgttgaccg tatgcgtcgt gaattcaaag ttgaagctaa cgtaggtgcg cctcaagtat
    24721 cttaccgtga aactttccgt gctggcactc aagccgaagg taagtttgta cgtcagtctg
    24781 gtggtaaagg tcaatacggt cacgtatgga ttgaatttac accaaatgaa gaaggtgctg
    24841 gtttcgaatt tgaaaatgcg atcgtcggtg gggttgttcc tcgtgaatac attccagctg
    24901 ttgaaactgg tttgaaagat gctatggaaa atggtgtctt agctggctat ccattagtag
    24961 atatcaaagc taaactttac gatggttcat accatgatgt cgattcaaat gaaactgcct
    25021 tccgtgttgc tgcttctatg gcattacgtg cagcagctaa gaaagctaat ccagtaatcc
    25081 ttgaaccaat catggctgta gaagttgtta tccctgaaga ttatttaggt gatgttatgg
    25141 gtcacgtaac tgctcgtcgt ggacgtgttg aaggtatgga agctcgcgct ggcggccaac
    25201 aagttgttcg tgcgatggtt ccacttgctg aaatgtttgg ttatgctaca actcttcgtt
    25261 ctgctactca aggtcgtggt acatttacaa tgacatttga ccactacgaa gatgtaccaa
    25321 aatcagtaca agaagaaatc attaagaaaa acggcggaaa agctgaataa tttcttaaaa
    25381 ccggatagtc ctgcaaagag attatccaaa gagactatat ttttaatata gtttcgtgta
    25441 aaataattat cgatgatatg ggcatgtggt gtaccttgtg tacatcatat acctatcaga
    25501 caaataaaaa atatattgta tttttaggag gacattttaa aatggcaaaa gaaaaatttg
    25561 accgttctaa accacacgtt aacattggta ctatcggaca cgttgaccat ggtaaaacta
    25621 cattaacagc tgcaatcaca actgtactat ctaagaaaaa cggcggccaa gctatggctt
    25681 acgatcaaat cgatggtgct ccagaagaac gcgaacgcgg aatcacaatc tcaacagctc
    25741 acgttgagta tgaaacagat acacgccact acgctcacgt tgactgccca ggacacgcgg
    25801 attacgttaa aaacatgatc actggtgctg ctcaaatgga cggagctatc ttggtagttt
    25861 ctgctgctga cggcccaatg cctcaaactc gtgaacacat cctattgtct cgtcaagttg
    25921 gtgttcctta catcgttgta ttcttgaaca aagtagacat ggttgatgac gaagaattac
    25981 tagaattagt tgaaatggaa gttcgtgacc tattaacaga atacgaattc cctggtgacg
    26041 atgttcctgt agttgctgga tcagctttga aagctctaga aggcgacgct tcatacgaag
    26101 aaaaaattct tgaattaatg gctgcagttg acgaatacat cccaactcca gaacgtgaca
    26161 acgacaaacc attcatgatg ccagttgaag acgtgttctc aattactgga cgtggtactg
    26221 ttgctacagg tcgtgttgaa cgtggacaag ttcgcgttgg tgacgaagtt gaagttgttg
    26281 gtattgctga agaaacttca aaaacaacag ttactggtgt tgaaatgttc cgtaaattgt
    26341 tagactacgc tgaagctgga gacaacattg gtgctttact acgtggtgtt gcacgtgaag
    26401 acatccaacg tggacaagtt ttagctaaac caggtacaat cacacctcat acaaaattct
    26461 ctgcagaagt atacgtgttg acaaaagaag aaggtggacg tcatactcca ttcttcacta
    26521 actaccgtcc acaattctac ttccgtacaa ctgacgtaac aggtgttgtt gaattaccag
    26581 aaggaactga aatggttatg cctggcgaca acgtaacaat ggaagttgaa ttaatccacc
    26641 caatcgctat cgaaaacggt actaaattct caatccgtga aggcggacgt acagttggtg
    26701 ccggtgtcgt tacagaaatc aaagcttaat tcacttaagt tttaaagtaa agcaacattt
    26761 attcggacgt aatcgctcgg aacgaaggtc ttaggatctt tgttccgagc ttttttattt
    26821 attgcaggat caggaaaaaa gacaggagta ttataaatag aagaaacacg aaataaaaga
    26881 gtcagtattt tctaaatgaa actttatgaa aacaaaatgt tttttacaag aaaaagcctt
    26941 gctttgtgag tttatatata ttataatgac aaaggtgcgt ttactttagt gaattgcaca
    27001 gacgtaatca gaatgatttc gtcggctaag aaacgagagg ttgcgacacg cccggacgct
    27061 ttgccacgaa cgagcgtgac ggaaattttc gtggagctat gtctactttt caaaataggc
    27121 gaaggaggga acaagatggc aaaacaaaaa attcgtatcc gtttaaaagc gtatgaacac
    27181 cgtattttag atcaatcagc ggataaaatc gtggaaactg caaaaagaac tggagctagc
    27241 gtgtctggtc caattccatt accaactgaa cgcagtcttt acacaatcat ccgtgcgact
    27301 cataaataca aagattcacg cgaacaattc gaaatgcgta cacacaaacg tcttatcgac
    27361 attgtgaacc caacaccaaa aactgttgat gctttgatga agctagactt accatctggt
    27421 gtaaacatcg aaatcaaatt ataaaactaa aacaaaaata atggaggtgt actcatgacc
    27481 aaaggaatct tagggaaaaa agtgggaatg acacaaatct tcactgaatc tggtgaatta
    27541 attccagtaa ctgttgtaga agctactcca aacgtagtac tacaagtgaa aacaatggaa
    27601 acggatggct acgaagctat tcaagttggt taccaagata tgcgtgaagt tttatcaaac
    27661 aaacctgcga aaggtcatgt tgcaaaagca aacacggctc ctaagcgctt cattcgtgaa
    27721 ttcaaaaatg ttgagctagg agaatatgaa gtaggaaaag aaattacagt agatgttttc
    27781 caagcaggag acattattga tgtaacaggt actacgaaag gtaaaggatt ccaaggggtt
    27841 atcaaacgcc acggacaaag ccgcggacca atggctcacg gttctcgtta ccatcgtcgt
    27901 cctgggtcaa tgggtccagt tgcacctaac cgtgtattta aaaacaaacg tcttgctggc
    27961 cgtatgggtg gcaaccgcgt aactatccaa aacttggaag ttgtacgtgt cgatgcagaa
    28021 agaaatgtta tcttgatcaa aggtaatgtt cctggagcta aaaaatcttt aattactatc
    28081 aaatcagctg tgaaagctaa ataattgtag gaagaaagga ggaactaagg aatgccgaat
    28141 gtagcattat tcaaacaaga tggaagccaa aacggtgaaa tcacacttaa cgaagaaatc
    28201 ttcggaattg aacctaatga aagtgttgtt tacgatgcaa tcgtaatgca acgtgcgtca
    28261 ttaagacaag gaacacacgc ggttaaaaac cgtagcgctg ttcgcggcgg cggacgtaaa
    28321 ccatggcgtc aaaaaggaac aggtcgtgca cgtcaaggat ctatccgctc accacaatgg
    28381 cgtggaggtg gcgtagtctt tggaccaaca ccacgttctt acagctacaa acttcctaaa
    28441 aaagttcgtc gtttagcaat gaaatctgta ttgtcagaaa aagttgctga aaacaacttg
    28501 gtagcaatcg aaggcttgaa cttcgacgca ccaaaaacaa aagaattcaa acaagttctt
    28561 gctaacttat ctatcgactc taaagtattg gttgttctag aaaaaggtaa cgactttgct
    28621 gctttatcag cacgtaactt accaaacgtt tctgtagtaa cttctgataa tgtgagtgtg
    28681 ctagacgttg tatcaaatac aaaagtgtta gcaacacaaa ctgctcttac tcaaattgag
    28741 gaggtgcttg cataatgaac ttactagacg taatcaaacg cccagtgatc actgaaaaat
    28801 caatgcttgc catggatgac aagaaataca cttttgaagt ggacactcgc gcaaacaaaa
    28861 ctttagtaaa acaagcggta gaagctgctt ttgacgttaa agtcaaaaac gtgaacatcg
    28921 tgaacgtacg tgcgaaattc aaacgtatgg gcaaatatgc aggatataca aaaaaacgtc
    28981 gcaaagcgat cgttacattg actgaagatt caaaagaaat ccaattattc gaagctgctg
    29041 aataagcact aatagataac tcattaaatt aggagggaaa aacgtggcga ttaaaaagta
    29101 caaacctacc tcaaatggtc gtcgtaacat gacaggttct gattttgctg aaatcacaac
    29161 atcaacacct gaaaaatcat tgttacaacc attgaaaaac catgctggac gtaacaacaa
    29221 cggccgcatc actgtacgtc atcaaggtgg cggacacaaa cgccaatatc gcgtgatcga
    29281 cttcaaacgt aacaaagata acgttgttgc aactgttcaa acgatcgaat atgatccaaa
    29341 ccgttcagct aacatcgcgt tagtacacta tgaagatgga gtgaaagctt acatcttagc
    29401 acctaaagga ctagaagtgg gtatgaaact tgtttcaggt ccagaagcag atatcaaagt
    29461 cggaaatgct cttccattag aaaacattcc agttggtact gttatccaca acattgaaat
    29521 gaaacctggt aaaggtggac aattgatccg ttctgctggt acaagtgctc aagtacttgg
    29581 taaagaaggc aaatacgtat tgatccgctt gaactctggt gaagttcgta tgatcttagc
    29641 tgcatgccgt gctacaatcg gttctgtagg taacgaacaa cacgaattaa tcaacatcgg
    29701 taaagctgga cgctctcgtt ggatgcgtaa acgcccaact gtacgtggta gcgtaatgaa
    29761 ccctaatgat cacccacacg gtggtggtga aggtaaagct cctatcggac gtaaagcacc
    29821 agtttctcct tggggtcaac cagctcttgg ttacaaaact cgtaacaaaa aagctaaatc
    29881 agacaaactt attgttcgtc gtcgcaaaaa taaataatta ctttgaccat gtgtcgcaca
    29941 ttttgagagg aggttcacca tgggtcgtag tttaaagaaa ggaccttttg tcgatgagca
    30001 tttaatgaaa aaagttgaag ctcaagcagg ggttgaaaag aaaaaagtta tcaaaacttg
    30061 gtcacgccgt tcaacagttt tcccaagttt tgttggatat accatcgcag tttatgatgg
    30121 acgtaaacat gtaccagttt acatccaaga agacatggta ggacacaaat taggtgaatt
    30181 tgcacctaca agaacttatc gtggacatgc tgctgacgat aagaaaacga aacgctaatt
    30241 tgaggggagg ataaatccaa atggcagaac aaatcacatc agctaaagca actgcaaaaa
    30301 cagttcgcac ttcacctcga aaagcccgtt tagtaattga ccttatcaga ggtaaaagtg
    30361 tcgcagatgc aatttcaatc ttgaaattca caccaaacaa atctgctgga atcattgaaa
    30421 aagtattgat gtcagcagtt gcgaatgcag aaaataactt tgacttagat gttgaaaact
    30481 tggtagtaag cgaagctttt gttaacgaag gacctacaat gaaacgtttc cgtcctcgtg
    30541 caaaaggatc agcttctcca atcaacaaac gtacaagtca tatcacggta gtcgtatcag
    30601 aaaaataagg agggataatc agtgggtcaa aaagtacatc caattggaat gcgtgtaggc
    30661 atcatccgcg actgggatgc taaatggtat gctgaaaaag agtatgctga gttcttacac
    30721 gaagatttaa gaatccgtaa atttatttca actaaacttg ctgatgctgc tgtatcaaca
    30781 gttgaaatcg aacgcgcaac aggtcgcgta aacatttcaa ttcacacagc taaaccaggt
    30841 atggttattg gtaaaggcgg ttctgaagtc gaaagcctaa gaaaagaatt aaacaaatta
    30901 actggtaaaa gaatccatat caatatcgtg gaaatcaaaa aaccagatct agatgcaaaa
    30961 ttagtaggtg aaggaatcgc acgtcaatta gaaaaccgtg ttgctttccg tcgcgctcaa
    31021 aaacaagcca tccaacgctc aatgcgtgct ggcgctcaag ggatcaaaac tcaagtatct
    31081 ggtcgtctaa acggagcaga tatcgctcgt tcagaaggat actcagaagg aactgttcct
    31141 cttcatactt tacgtgcgga cattgattac gcatgggaag aagcagatac aacatacgga
    31201 aaactaggag ttaaagtgtg gatctatcgt ggagaaattc ttccaactaa aaaaaacact
    31261 gagaaaggag ggaaataatc atgttagtac ctaaacgtgt aaaacaccgt cgtgaattcc
    31321 gcggaaaaat gcgcggggaa gctaaaggcg gaaaagaagt agcattcggt gaatacggtt
    31381 tgcaagctgt tgattcacat tggatcacaa accgccaaat cgaagctgct cgtatcgcaa
    31441 tgactcgtta catgaaacgt ggtgggaaag tatggattaa aattttccct cacaaatctt
    31501 atactgccaa agcaattggg gtacgtatgg gttctggtaa aggggcacct gaaggatggg
    31561 ttgcaccagt aaaacgtggt aaaatcatgt ttgaaatcgc aggcgttcct gaagaagtag
    31621 ctcgtgaagc gttacgtcta gcttctcaca aattaccaat gaaaactaag atcgtaaaac
    31681 gtgaggaaat gggtggtgaa tcgaatgaag gttaaagaaa tcagagaatt aaccactgcc
    31741 gaaatgcttg atcaagaaaa acaattaaaa gaagaattgt ttaatcttag attccaatta
    31801 gcaacaggtc aattagaaaa cactgcacgt attaaagaag tacgtaaatc gattgcacgc
    31861 atcaaaactg tgttgcgtga acaagctaag taattatgga aggaggccat taagcgtatg
    31921 actgaaggaa gaaatcaacg caaagtttat caaggtcgcg tggtttcaga caaaatggat
    31981 aaaacaatta ccgttgctgt cgaaacaaag aaaaaccacc ctatctatgg caaacgcatg
    32041 aactattcta agaaatacaa agtgcatgat gaaaacaaca cagcaaaagt tggcgacatc
    32101 gtgagaatta tggaaactcg tccattatca gctacaaaac gtttccgttt gttggaagta
    32161 gtcgaagaag cagttattat ctaataacac gagattttcc tatatagatt gaatgcaaaa
    32221 tctgaaagga ggatacacaa cgtgatccaa gcagaaagtc gtttaaaagt cgctgataac
    32281 tcaggcgcac gtgaaatttt gacgatcaaa gtccttggtg gatctggtcg taaaactgct
    32341 aacatcggtg atgtgatcgt tgctacggtt aaacaagcaa cgccaggtgg ggttgtcaaa
    32401 aaaggtgacg tcgttaaagc cgttatcgtt cgaacaaaat caggagctcg tcgtacagac
    32461 ggttcatata ttaaatttga tgaaaatgct gcagtgatta ttcgtgatga taaaagccct
    32521 cgtggaacac gtatctttgg gccagttgca cgtgaactac gtgaaaacaa cttcatgaag
    32581 atcgtttcac tagcaccaga agttttataa tcttgagaca cttatcaaag gaggtgcgaa
    32641 acagttatgt ttgttaaaaa aggcgataaa gttaaagtta tcactggaaa agacaaaaac
    32701 aaagaaggcg ttgtactagc agcgttcccg aaaaaagata aagttattgt cgaaggtgta
    32761 aatgtcgtta aaaaacacca aaaaccttct caagctgctc ctcaaggtgg aattgttgag
    32821 atggaagcgc caattcatgt ttctaacgtg atggtggttg actctactgg tgtagctggc
    32881 cgagttggct acaaagaagt agacggcaaa aaagtccgtg tttctaaaaa aaccggtgaa
    32941 gttttagata aataaaagtt taaggaagga gggtcttact gaatgaaccg cctaaaagaa
    33001 aaatatctta aagaagtaac tccatcattg atggaaaaat ttaactatag ctctgttatg
    33061 caaacaccta aagttgaaaa aatcgtcatc aacatgggtg ttggtgatgc ggtatcaaac
    33121 gctaaaaact tagataaagc agttgaagaa ttaactttga tcactggtca aaaaccaatg
    33181 attacaaaag ctaaaaaatc aatcgctgga ttccgtttac gtgaaggaat gccaattggt
    33241 gcaaaagtta cattgcgcgg agaaagaatg tacgaattct tagacaaatt ggtttctgtt
    33301 tcactaccac gtgtacgtga cttccatggt gtaagtaaaa aagcctttga cggtcgtgga
    33361 aactatactt taggtattaa agaacaattg atcttcccag aagtagatta tgatttagta
    33421 gataaagtac gtggtatgga catcgttatt gtaacaacag caaactctga tgaagaatct
    33481 cgtgagttgt tgacacaatt aggcatgcca ttccaaaaat aattaaagga ggcgaactac
    33541 gtggctaaaa aatcaatgat tgctaaaaac aaacgtcctg caaaattttc aacacaagct
    33601 tatactcgtt gcgaacgttg cggacgtcca cattcagttt atcgtaagtt ccatctttgc
    33661 cgtatttgct tccgcgaact tgcctataaa ggtcaaattc ccggcgtgaa gaaagctagc
    33721 tggtaaaaag taaattcgca taagaaggag gtaaaagatc aatggtcatg acagatccaa
    33781 ttgcagattt tctaactcgt atccgtaacg caaacatggt taaacatgag tctttagaag
    33841 tacctgcatc aaaaattaaa cgtgacatcg ctgaaatctt gaaacgtgaa ggtttcgttc
    33901 gtgatgttga atacatcgaa gatgacaaac aaggcgtgat ccgtgttttc ctaaaatttg
    33961 gtaaaaacgg cgaacgtgtt atcacaaact taaaacgtat ctctaaacca ggtttgcgtg
    34021 cttatgtcaa agctgacgaa gtaccaaaag tattgaacgg tttaggtatc gcaatcattt
    34081 cgacttctga aggtgttgtc actgataaag aagctcgtga aaaaaatatc ggcggcgaag
    34141 ttatcgctta cgtatggtaa tcaagtagaa tctacaagga ggtgtcttta agtgagccgt
    34201 atcggaaata aagtcgttgt tatccctgaa ggagtaacag ttactcaaga cggaaacaac
    34261 gttacagtta aaggaccaaa aggtgaattg actcgtactt tttcagcaga tatcaaaatg
    34321 aatatcgaag gaaacgaagt aactttcact cgtccaaacg acagtaaaga aatgaaaaca
    34381 attcatggaa caactcgtgc gaacttcaac aacatggttg taggtgtcag cgaaggtttc
    34441 caaaaagcgt tagaactaat cggggttggg taccgtgcac aattacaagg atcaaaactt
    34501 gtattgaacg ttggttactc acatccagta gaaatcacac caccagctgg agtaactgtt
    34561 gaagtaccag ctaacacaca agtaattgtt aaaggtgcga acaaagaaga agttggcgaa
    34621 ttagctgcaa acattcgtgg aactcgtcct ccagaacctt ataaaggtaa aggtattcgt
    34681 tatgttggcg aatatgtacg ccgtaaagaa ggtaaaactg gtaaataatc gtttagaaaa
    34741 attgcataga agccagcagc aggaaaaagg catttggctg aagtttacct tcaaaaaaat
    34801 acatttttac ttgtgccgca gcttctattt ttcgaaacgt atttactgct tgaaatagta
    34861 gtacaataaa aataaagagg tgacaattgt gattacaaaa ccagataaga acaaaacacg
    34921 tcaaaagaga catcgtcgtg tacgtaacaa tatctctggt actgctgagc gcccacgctt
    34981 gaacgttttt cgttctaaca aaaacatcta cgctcaaatt attgatgacg tagcgggtgt
    35041 aacgctagca agtgcctcta ccttggataa agaaatttca ggtggaacaa aaacagaagc
    35101 agcacaagct gtcggtaaac tagttgctga acgtgcagct gaaaaaggca ttaaagtagt
    35161 agtctttgac cgtggtggat acctttacca tggccgtgtg caagctttag ctgaagctgc
    35221 tcgcgaaaat ggactagaat tttagaagaa ggaggaatac cattcatggt ttatatcgat
    35281 ccaaaacatt tggaattaga agaccgcgtt gttgcaatta accgtgtaac aaaagttgtt
    35341 aaaggtggac gtcgtctacg ttttgctgct ttagttgttg tcggtgacaa aaacggacac
    35401 gtagggtttg gtacaggtaa agctcaagaa gttcctgaag caatccgtaa agcaattgaa
    35461 gatgcgaaga aaaacttagt tgaagtacct atggttggtt caacaatccc acacgaagta
    35521 atcggtgctt ttagtggtgg tagaatccta atgaaacctg ctgtagaagg ttctggggtt
    35581 gctgctggtg gaccagttcg tgccgtatta gaattagctg gggtagcaga tatcacttct
    35641 aaatctttag gctcaaatac accaatcaac gttgttcgcg caacagttga aggtttgaaa
    35701 caattgaaac gtgcagaaga agttgcagaa cttcgcggca aatcagttga agaattaatc
    35761 ggataaggag gacaacaata atggctgaat taaaagttac tttaaaacgc agtattatcg
    35821 gacgtcctca aaaccaacgc gatacagtta aagcgttagg tcttacaaag attaacagtt
    35881 cagtggttaa gccttctaat gaagcaatta aaggcatgat caatactgtt tctcacctag
    35941 tggacgttga agaaatttaa tttagaaaaa tcataactag aacattaagg aggtgccaaa
    36001 cctatgaaac ttcatgaatt aaaacctgct gaaggttcac gccaagtacg taaccgtgtt
    36061 ggtcgtggta cttcatctgg taacggaaaa actgccggac gcggacaaaa aggacaaaaa
    36121 gctcgttcag gcggcggtgt gcgtttagga tttgaagggg gacaaacacc attgttccgt
    36181 cgtttaccaa aacgaggatt cacaaacgtg aaccgtaaag actatgcagt cattaatctt
    36241 gatgtattga accgctttga agacggagct gaagtaactc ctgttgcttt agttgaagct
    36301 ggaatcgtga aaaacgaaaa agctggaatc aaagtattag ctaatgggga actaaacaag
    36361 aaattaactg tgaaagcagc aaaattctct aaagcagctc aagaagcaat tgaagcggct
    36421 ggtggatcaa tcgaggtgat ctaatgttta gactattaaa agatgctttt aaagtaaaag
    36481 acattagatc gaaaatccta tttactgtat ttgtgttgtt tgtatttcgc ctaggtgcac
    36541 atattactgt accaggcgta aatgctgctt cattgcaaaa cctttcttct ttgccatttt
    36601 tcaacatgtt gaacttggta agtggtagtg cgatgcaaaa cttttccatt ttctcaatgg
    36661 gggtttcacc atacattact gcttctatcg tcattcagct tcttcaaatg gacatcgtgc
    36721 ctcgatttgt tgaatggtcg aaacaagggg aagttggtcg taaaaaactg aatcaagcga
    36781 ctcgatatct gacattagta ttggcattta tccaatctgt cggtatcact gctggattca
    36841 atcaatacgc tcaattaggt ttcgtgaata atcctaacgt agcaacttac gtaacgatcg
    36901 gtttgattct aacagccggt acgatgtttg ttacttggct aggagaacag atcacagaaa
    36961 aaggtatcgg aaatggcgta tcaatgatca tttttgcagg tatcatttct agattgcctg
    37021 aaagtatcag agaaatttat gaagattact ttataaatat tgatccttca gacatatgga
    37081 aatctgctat ttttgtggcc attttactag tagcggtctt gttgatcgtg acattcgtaa
    37141 catttttcca acaagctgaa cgcaagatcc cgatccaata tacgaaacgc gtagctggcg
    37201 cgcctacaag cagctatctg ccgttgaaag taaatgcagc tggagttatt ccagttatct
    37261 ttgctagttc gtttattgct acgccaaatg ctgttttaca agcattgagc ggtagattcg
    37321 gttctgaaaa ctggtacaaa gtgatgatgg agatctttaa ctataataca gcacctggtg
    37381 ctacgattta tacgattctg atcgttgcct tcactttctt ctacgccttt gttcaagtaa
    37441 accctgagaa attagcggaa aacttgcaaa agcaaggaag ttatatacca agcgtacgcc
    37501 ctggtaaggg gactgaagag tatgtctcaa gattactgat gcgtttaagt acagttggtg
    37561 cagtcttcct tggtttagtg gcattgcttc caatcattgc tcaaatggtt tgggatcttc
    37621 cacaatcaat cggattaggc ggtacaagct tactgatcgt tatcggtgta gctttagaaa
    37681 ctgcgaaaca gttagaaggc ttaatgctga aacgtaaata tgttggattc attgagtaag
    37741 aaagcgtgtt gaggtttccc ctcaacacac gttctcacac atttattagg agggaaaaca
    37801 atgaacctca ttttaatggg gctgccaggc gcaggtaaag gaacacaagc tgaaaaaatc
    37861 attgatgctt atggtattcc gcacatctca acaggagata tgttccgcgc agcgatgcaa
    37921 aacgaaacag ctcttggcct ggaagcaaag tcttatatgg ataaaggtgc attagttcct
    37981 gatgaagtaa caaatggaat cgtgaaagag cgactagctg aaccagatac agagaaaggc
    38041 ttcttattag atggctttcc acgtacgcta gatcaagcaa aagctctgga cgcaatgcta
    38101 aaagatttga ataaaaaaat tgatgctgtc atcgatatcc atgttggtga agaaatcttg
    38161 gtcgaacgtc tagccggccg atttatctgc agcaattgtg gagcaactta ccataaaatt
    38221 ttcaacccta caaaagttga agacacatgt gatcgttgcg gtgggcatga attctatcaa
    38281 agagaagatg ataaacctga gacggttaaa aatcgtctgg ctatcaacat caaaaatagt
    38341 gaaccaatct tggcttatta taaagaacaa ggtttgctaa acactattga tggtgctcgt
    38401 gaaatcgatg ctgtatttgc agatgtacaa aaaatcattg aaaaatagca cgattgcccg
    38461 tagccgactt gcattatgca gttactcttg tcaagttcaa taaattatga tagaatatgt
    38521 cagtccgact tctagagaat cctctagatg atccattttg agaattttga ggtgggaact
    38581 gcagtttccg ccattttatc gtgtgaaaat gcgaaacaag tacaaggagg tactgtgcgt
    38641 ggcaaaagaa gatatgattg aagtcgaagg tacagtcgtc gaaactttgc cgaatgcaat
    38701 gtttaaagtt gaactagaaa acggacacca agttcttgct actgtttcag gtaaaattcg
    38761 tatgcattac atccgtatct tacctggtga caaagtaacg gttgaattgt ctccatacga
    38821 tcttaaccgt ggccgtatta cttatcgctt taaataattg tactccgtaa aactacagga
    38881 ggtattatca tgaaagtaag accatcagta aaaccaatgt gcgaacattg taaagtaatt
    38941 cgtcgtaaag gacgcgttat ggtgatttgc ccagcaaatc caaaacataa acaacgtcaa
    39001 ggataattgg aggtgctata aatatggctc gtattgcagg agtagatatt cctcgtgata
    39061 aacgtgtagt agtttcactt acttatatct atggtattgg taacactact gctaaaaaga
    39121 tcttagctga tgctggtgta tctgaagatg ttcgcgttcg tgaattaacg aatgaacaaa
    39181 cagatgctat ccgtgcagaa gtagataaat taaaagttga aggggatctt cgtcgtgaag
    39241 tgaacttgaa catcaaacgt ttgatggaaa tcggttctta ccgtggaatc cgtcatcgcc
    39301 gtggattgcc tgttcgtgga caaaacacga aaaacaatgc acgtactcgt aaaggcccag
    39361 ctcgcgctat cgctggcaag aaaaaataat tcttaagtga aggaggttaa aacttcatgg
    39421 cagcaaaaaa agtgaatcgt aaacgccgtg tgaagaagaa tatagaagca ggtattgcac
    39481 atatccattc tacattcaat aacactatca tcatgatcac tgatactcac ggaaatgcat
    39541 tagcgtggtc atcagctggt tcattaggtt tcaaaggaag caaaaaatca actccttttg
    39601 ccgctcaaat ggcagcagaa actgctacaa aagcagcaat ggaacacgga ttaaagactg
    39661 ttgaagtaac agttaaagga cctggttctg gacgtgaagc agcaattcgt tcattacaag
    39721 ctacaggttt agaagtgact gcaattcgtg acgtgactcc agttcctcat aatggtgccc
    39781 gccctccaaa acgccgtcgt gtttaatgag tgccgctcat tttgagtttt atcagtaacg
    39841 tcattgaaca agacactttt cgttttgaaa ggggtaaaga taagaatgat tgagttcgaa
    39901 aaaccaagaa tcgcaaaaat tgatgaagaa aaagattatg gcaagttcat cgttgaacct
    39961 cttgaaagag ggtatgggac tactttaggg aattccctac gtcgtatttt attatcttct
    40021 ttgccaggtg ctgccatcac taatattcaa atcgatggtg tactgcatga attctctacc
    40081 atcaaaggtg ttagagaaga cgtcactcaa atcatcttga acattaaagg cttagcgctg
    40141 aaaatgtatg gccaagaaga aaaaaccctt gaaatcgata ttaccggacc tgctacagta
    40201 actgctggcg atattatcgt tgatagtgat gtagaaattc ttaacaaaga tatgtacatc
    40261 tgtagtgtct ctgaaggagc tacgttccat gctcgcttaa cagtgaaacc tggacgtggt
    40321 tatgttcaag cagatgaaaa taaaaaagaa gatatgccaa ttggcgttct tccagtcgat
    40381 tcaatctaca cacctgttcg tcgtgtgaac tatcaagttg agaacacacg tgttggacac
    40441 cgtgaagatt ttgataaatt gacgatggag atttggacag atggttcaat tgaaccgttg
    40501 gaagcaatga gtttgtctgc gaaaatcatg actgaacatt tggatatttt tgtgaactta
    40561 actgatgaag caaaaaatgc tgaaatcatg gtcgaaaaag aagaaacaca aaaagaaaaa
    40621 atgttggaaa tgacgatcga agagttagac ttgtctgttc gctcttacaa ttgtttgaaa
    40681 cgtgcaggaa tcaatactgt acaagaactt acaaataaat ctgagcctga aatgatcaaa
    40741 gtccgtaact taggacgtaa atcattagaa gaagttaaag caaaattgca cgacttaggt
    40801 ttaggtttac gtaaagaaga ttaaaacctt ttacgaagga gggaaaccaa cgtgagttat
    40861 cgtaaactag gacgcacatc tagccaacgt aaagcgatgt tgcgtgattt aacaactgat
    40921 ttattaatca acgaacgtat tgtgactact gaagctcgtg cgaaagaagt tcgctcaact
    40981 gcagaaaaaa tgatcacttt aggtaaacgc ggagatttgc atgcacgtcg tcaagctgcg
    41041 gctttcgtac gtaatgaagt tgccagcgtg cgtgaagaaa atgaggacat cgtcattgaa
    41101 tcagctttac aaaaactgtt caacgatatt gcacctcgtt acgcagaacg tcaaggcgga
    41161 tacacacgca ttttgaagac agaaccaaga cgcggtgatg gtgcaccaat ggttgtctta
    41221 gaacttgtct aaaatcacac taataacatc actttataga tgattctttt agagtgttat
    41281 gatgttggaa gatatttttc cgagtctagc tcagcgctgc tcctcaagcg aatatcgctt
    41341 ggggagtaag cactcatcat aaagtgtttt ttt
//
LOCUS       DAXQKX010000020        40286 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.020, whole genome shotgun sequence.
ACCESSION   DAXQKX010000020 DAXQKX010000000
VERSION     DAXQKX010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 40286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40286
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.020"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..556)
                     /locus_tag="ACF3MF_001182"
     CDS             complement(<1..556)
                     /locus_tag="ACF3MF_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HFE3927193.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGA"
     gene            complement(572..1051)
                     /locus_tag="ACF3MF_001183"
     CDS             complement(572..1051)
                     /locus_tag="ACF3MF_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HFE3927194.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKARLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(1057..2081)
                     /locus_tag="ACF3MF_001184"
                     /pseudo
     CDS             complement(1057..2081)
                     /locus_tag="ACF3MF_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
     gene            complement(2098..3204)
                     /locus_tag="ACF3MF_001185"
     CDS             complement(2098..3204)
                     /locus_tag="ACF3MF_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFE3927195.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(3433..6030)
                     /gene="adhE"
                     /locus_tag="ACF3MF_001186"
                     /gene_synonym="adhC"
     CDS             complement(3433..6030)
                     /gene="adhE"
                     /locus_tag="ACF3MF_001186"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HFE3927196.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(6335..6715)
                     /gene="yajC"
                     /locus_tag="ACF3MF_001187"
     CDS             complement(6335..6715)
                     /gene="yajC"
                     /locus_tag="ACF3MF_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HFE3927197.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(6812..7957)
                     /gene="tgt"
                     /locus_tag="ACF3MF_001188"
     CDS             complement(6812..7957)
                     /gene="tgt"
                     /locus_tag="ACF3MF_001188"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HFE3927198.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            8175..8873
                     /locus_tag="ACF3MF_001189"
     CDS             8175..8873
                     /locus_tag="ACF3MF_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HFE3927199.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(9041..11680)
                     /locus_tag="ACF3MF_001190"
     CDS             complement(9041..11680)
                     /locus_tag="ACF3MF_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFE3927200.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(12299..13330)
                     /gene="queA"
                     /locus_tag="ACF3MF_001191"
     CDS             complement(12299..13330)
                     /gene="queA"
                     /locus_tag="ACF3MF_001191"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HFE3927201.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            13523..14128
                     /locus_tag="ACF3MF_001192"
                     /pseudo
     CDS             13523..14128
                     /locus_tag="ACF3MF_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(14281..15429)
                     /gene="tnpB"
                     /locus_tag="ACF3MF_001193"
     CDS             complement(14281..15429)
                     /gene="tnpB"
                     /locus_tag="ACF3MF_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element RNA-guided
                     endonuclease TnpB"
                     /protein_id="HFE3927202.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSS
                     GKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQ
                     RKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDI
                     ICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICS
                     ECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
     gene            complement(15446..15850)
                     /gene="tnpA"
                     /locus_tag="ACF3MF_001194"
     CDS             complement(15446..15850)
                     /gene="tnpA"
                     /locus_tag="ACF3MF_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HFE3927203.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKE
                     MFWSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
     gene            16008..16589
                     /locus_tag="ACF3MF_001195"
                     /pseudo
     CDS             16008..16589
                     /locus_tag="ACF3MF_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
     gene            16593..17234
                     /locus_tag="ACF3MF_001196"
     CDS             16593..17234
                     /locus_tag="ACF3MF_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFE3927204.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            17231..18148
                     /locus_tag="ACF3MF_001197"
     CDS             17231..18148
                     /locus_tag="ACF3MF_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HFE3927205.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            18145..18816
                     /locus_tag="ACF3MF_001198"
     CDS             18145..18816
                     /locus_tag="ACF3MF_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFE3927206.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(19357..19845)
                     /locus_tag="ACF3MF_001199"
     CDS             complement(19357..19845)
                     /locus_tag="ACF3MF_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HFE3927207.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(20046..20312)
                     /locus_tag="ACF3MF_001200"
     CDS             complement(20046..20312)
                     /locus_tag="ACF3MF_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFE3927208.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(20312..20575)
                     /locus_tag="ACF3MF_001201"
     CDS             complement(20312..20575)
                     /locus_tag="ACF3MF_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFE3927209.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            21096..21236
                     /locus_tag="ACF3MF_001202"
                     /pseudo
     CDS             21096..21236
                     /locus_tag="ACF3MF_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            complement(21378..23201)
                     /locus_tag="ACF3MF_001203"
     CDS             complement(21378..23201)
                     /locus_tag="ACF3MF_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFE3927210.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(23799..26504)
                     /locus_tag="ACF3MF_001204"
     CDS             complement(23799..26504)
                     /locus_tag="ACF3MF_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HFE3927211.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(26810..27757)
                     /locus_tag="ACF3MF_001205"
     CDS             complement(26810..27757)
                     /locus_tag="ACF3MF_001205"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HFE3927212.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            27947..28216
                     /gene="rpsN"
                     /locus_tag="ACF3MF_001206"
     CDS             27947..28216
                     /gene="rpsN"
                     /locus_tag="ACF3MF_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFE3927213.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(28392..28754)
                     /locus_tag="ACF3MF_001207"
     CDS             complement(28392..28754)
                     /locus_tag="ACF3MF_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFE3927214.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(28765..29886)
                     /gene="alr"
                     /locus_tag="ACF3MF_001208"
     CDS             complement(28765..29886)
                     /gene="alr"
                     /locus_tag="ACF3MF_001208"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HFE3927215.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(29902..30252)
                     /gene="acpS"
                     /locus_tag="ACF3MF_001209"
     CDS             complement(29902..30252)
                     /gene="acpS"
                     /locus_tag="ACF3MF_001209"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HFE3927216.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(30382..31893)
                     /locus_tag="ACF3MF_001210"
     CDS             complement(30382..31893)
                     /locus_tag="ACF3MF_001210"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFE3927217.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(32215..33567)
                     /gene="murF"
                     /locus_tag="ACF3MF_001211"
     CDS             complement(32215..33567)
                     /gene="murF"
                     /locus_tag="ACF3MF_001211"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HFE3927218.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLAATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(33720..34796)
                     /locus_tag="ACF3MF_001212"
     CDS             complement(33720..34796)
                     /locus_tag="ACF3MF_001212"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HFE3927219.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            34992..36737
                     /locus_tag="ACF3MF_001213"
     CDS             34992..36737
                     /locus_tag="ACF3MF_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/UbiB family protein"
                     /protein_id="HFE3927220.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(37017..37454)
                     /locus_tag="ACF3MF_001214"
     CDS             complement(37017..37454)
                     /locus_tag="ACF3MF_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HFE3927221.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(37438..38811)
                     /locus_tag="ACF3MF_001215"
     CDS             complement(37438..38811)
                     /locus_tag="ACF3MF_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927222.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(39133..39621)
                     /locus_tag="ACF3MF_001216"
     CDS             complement(39133..39621)
                     /locus_tag="ACF3MF_001216"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFE3927223.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(39643..40245)
                     /locus_tag="ACF3MF_001217"
     CDS             complement(39643..40245)
                     /locus_tag="ACF3MF_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFE3927224.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT        11481 a         8600 c         7336 g        12869 t
ORIGIN      
        1 aagcgcctac gagataacct cccataaaca aagcagagat cgaagcacca ccagcaacaa
       61 gtgaatacat gataaaagca gtacttggag gaatgaccat acctgtcgga gctgacgcga
      121 tattgaccgc tgtcgcaaac ttccggtcat atccttcttc cacttgctga gggatcaaca
      181 ctccaccaat cgcggtagaa gcggcaatgg ccgagctaga gatggaacca aataaagcat
      241 tccctaacac attcgtatga gccaaagccc ccggcacgcg cccgacgaac aacatcgcaa
      301 aatccactag tttcttagct atccctccat tattcatgat aatgcccgag agaacgaaaa
      361 acggaatagc gatcagcgaa aaactattga tacttcccac cattttttga gctgaactaa
      421 aagcagaaac atcaaacggt ataactaaca ataaagtcat catcgatgag aatgcaatac
      481 ttatagcaat cggcatccct aatacaagca acacaacaaa tacaaaaaat aacactaatc
      541 cggcttctat tgccatttta ttcctccatt tttatatttt ttcttgaatt gctggcttgt
      601 tgcttaatgt atcgattaga ttgatcaggc tatagataat gatgagtacc cccgatacag
      661 gtactgacag ataaacatat cccataggaa tacttaaaga aggcgagatc tgccccattg
      721 tcaatgtgac agcattccat ccgccataca ccatgatcat cgcagcaaat accagaaata
      781 aactttgaac aacaacttct aaaattttac tttttttgcc agttaatttt tcacttaaaa
      841 ccgttacggc taaacgtgct ttttgtccca caacatacgc ggaagacaac atggcaaacc
      901 agacaagacc gaatcgaaca agctcttccg tgaccgtatt tggatttcct aaaaccgttc
      961 tggaaaatac ttgccataaa acaacagcga ccatcccaac aagcaaaaca gctcccagga
     1021 tctctaatac cttgtttaaa atcattttca ttacagctac gctccttgct cttggatctt
     1081 ttgataaagg tctttgtagg taggatcgtt tttgaatata tcatgaagtg gggcaactgc
     1141 ctctcgaaac ggtgtattat ctacatcatt gaattggact ccatgttctt cttgtgctaa
     1201 agctttttct tcttcaattg cttttgcaaa agcttcaatt tcaaaaaccg ttgattcttt
     1261 cgctgcttct tcaatggctt tttcctgttc atcagttagc tgttctttga tggcatcatt
     1321 catgatgatg atatctggca cacgtgtatg ctcatcatag gaatagtatt tagctacccc
     1381 gccatgtcca gctgtataca agacaaattc attgttttct gatccgttga tcaaattgga
     1441 ttgaagagac gtgtacactt catcacttcc cataggtacg ggcgaaccgc ctaaaagctc
     1501 taccattttg atagcggttt cgctttgcat cacacggatc ttctttccct tcaaatcttc
     1561 cggcgtatgg atcggaccgt ctaccatata aaagctgcgc tgaccagaat cataataggt
     1621 caatccggta aatcctaaat ttttggtcga ttggtagatt ggctccatta tttcttcatt
     1681 atccatcacc ttaaagaaat gttcttcatc attgaataga taaggaacgg aaaaaatcga
     1741 ataatcttta gagaaacttt ccaacgctga ggcacttact tttgtgaaat ctactgctcc
     1801 tgactgtgtc aattcgatca gttcacgttc tccacccagt tgtccatctg ggaaatactg
     1861 gatctgtacg gaaccatctg ttttttcttt tactaaacgc ccaaattcat tcattgcatc
     1921 aattactggc tgttgcttgc ataagcaaag cgcaaggtaa ctatctcatt tacgtctgca
     1981 tctgcgacag ttgccacact agaattattt ccgcagccgc ttagacctag cagacctagg
     2041 ctaagcgaac ttgctgcaaa cagcagtgat gtttttttca tatgggtttc ctttctttta
     2101 acaataagag acgagcaatt ctgtcaaaca aagcaccgtt aacgactgtc cataaggcat
     2161 tgctgtgatt ccgatattcc gataaaaatc taaactgtcc cccattcctg tcccgattga
     2221 aacgttttga acttctcctt tttcatcgat ttgttcaagc aatccttgga tagcacgata
     2281 agcgacttct ttatattctt gtggtaaata acgtttatgg accgctttca aaataccgta
     2341 agcaaatcct gcagttgcag aagattctac gtaagaagaa ggatcatcca acaacgtatg
     2401 ccataaaccg ctttcagact gataagtttt taatgcacgc acttgtgctt caagtgtttc
     2461 gatcaataat ttgcgcaatg catcttcttt cgataattct aagatttcaa tgatctctgg
     2521 aatagcaatc gtcaaccagc agtttccacg agcccaaaat gcttcggcat agttatgatt
     2581 tccttcaaac gtccagccgt gataccacaa tcctgttcgt ttatccatca agtatttgat
     2641 atggatcata aactggtaac gagcttcttc taaatattct gggcgattca acagtttccc
     2701 gatttttgcc aaaggaagca ctgtcatcat caatgtatcg tcccacaact gattcttatt
     2761 ttccggtcca tatgtggcat gctgtaaccc gtcttcattt gtccgaggca tgtcattcat
     2821 gacccattct gcccattgtt ctaaataagg caaatagcgt gaatctttcg tgtcttcata
     2881 caagtaagcc atagtcaata gcggtgccat tgtattgacg tttttgggcg gagcgccttc
     2941 ttccatacga tcctcaaacc attcattgac cacttgataa gcgcgaggat tttttgtcat
     3001 ctggtaattt ttataaatac catatagacc gacaccttgt ggccaattcc acactgtcca
     3061 gcttttgtca tctactttca gtccatcaaa gtccaacaaa aattcaccat tatcgtcttt
     3121 gatcgttgtc aggttttcaa cgagcaggtc aattttttct ttcactaatt ctttaggtac
     3181 aaaaatctct tctttaataa tcatctttac gccacctttt taaacgcttt cattttatat
     3241 ccttaatata gcagtaatac cgtccactat aaatatcgct ttttgaacaa aaactgtcta
     3301 aaattgacct aaatgttaaa taacaaaagt aactttcagt tacttggaaa ttaaaaaaag
     3361 aacttggaga aacaacgttt tccaagttct ttttcatcta ttttcttatc ttttttctac
     3421 gctttctttt gcttatccgt tgtaagcatc aatgatgatc tgtttcaatt cagagatcaa
     3481 tggttctttc ggattagctg tcgtacattg gtcttcgtaa gctaattcag ccatacggtc
     3541 tacggttgta tctagtgttt cttgtgtgac tccttgagct tttagactca tgttgatgcc
     3601 gacagatttt cctaattcat aaacagccgt tgctaaagct tcgactaatt cctctgttgt
     3661 ttcgcctttc agacctaaga attttgcgat atctgcgtaa tctgtatctg cacggaaata
     3721 gtcatattta gggaacatcg catgtttttg tggatctttt gcattatagc ggataatatg
     3781 cggtaaaaga atcgcatttg tccgtccatg agggatcccg tattccccgc cgattttatg
     3841 tgcgactgag tgacaaatac ctaggaatgc gttagcaaac gccataccag ccattgtaga
     3901 agcgttgtgc attttttcac gtgattccat atcaggtgtt tttactgatt tttctaaata
     3961 gtcaaagact aacttgattg cttgtaggct caatccacgt gtataatctg aagccatgac
     4021 tgaaacatag gattcgattg catgtgttaa cacatccatc ccggtatctg ctgtgacaga
     4081 tgctggaact gacatgacga attgaggatc gacgattgcg acatctggcg tcaatgcata
     4141 atctgctaac ggatatttca catgtgtttc actgtcagtg atgaccgcaa atggcgttac
     4201 ttcagaacca gtccctgatg ttgtcgggat acatacgaat tgtgtttttt ctggtttgtc
     4261 gatcttatat gtccgtttac ggatatccaa gaatttttgt tttgcaccaa agaaagatgt
     4321 gtctgggtgt tcatagaaca tccacattcc cttagctgcg tccattgcag aaccgcctcc
     4381 aagagcgatt actgtatctg gcttgaagtc tgccatcagt ttcgttcctg cgtatacggt
     4441 atttgtcgat gggttcggtt caacatctga gaagacttcg atcttcacat catttttacg
     4501 tcgtgccaat acttcacgaa ctgtatcgca gtaaccgaat tggaccatac cagggtcaca
     4561 aacgatcatg acacgttcaa cgttttccat tttctctaag tacaatagag agttcttttc
     4621 aaagaagatt tttggcggta atttgaacca ttgcatgtta tttctccgtt tcgctacagt
     4681 tttgacattg attaagttta cagcagagac gttacgagaa acagagttct taccataaga
     4741 accgcatccc aaagtcaatg acggaatcat ttcgttatag atatcaccga tgccgccttc
     4801 tgcagatggt gtattcacta aaatacgaca agctttcatt cgaagaccga atttgacatg
     4861 caactcttcg ttttctgaat ggataactgc tgtatgtcct aatcctccaa gattcaacat
     4921 accttcacac aaatcaaacg catggtccgt gttgttagct ttgatcatgg caagaactgg
     4981 agaaagtttt tctcttgata gcggataatc tgggcctacg ccttccaatt cagcaatcag
     5041 cattttcgtt ccttttggta cactgattcc tgccaatttt gcgatttcca tcgcagaatg
     5101 tccaacgatt gatggattga ccgcatattt tccttcgttc atcactgcat cttctaattt
     5161 ttgcaattca tctggtttta cgatataaac ttggtgtgct tggaattctg cttttactgc
     5221 tgcatagatt tctttatcca cgatcacagc ttgttcagaa gcacaaatca ttccattatc
     5281 aaatgttttc gaaacgatca aatcgttcac tgcacgttta atttttgctg ttttttcaat
     5341 ataagctggt acgttacctg gacctacacc taaagctggt tttcctgtag agtaagcaga
     5401 cttgaccatt ccagctccac ctgtcgctaa gacgatcgcg atacctggat ggttcattag
     5461 catagaagtc gcttcgatcg aaggatgttc gatccattgg atacaatttt caggagctcc
     5521 ggcagcgata gcagcatcac gtaccactcg tgctgcttct gcagaagatt tttgggcact
     5581 tggatggaaa gcaaaaacga ttggatttct tgttttcaac gcgatcattg atttgaaaat
     5641 cgttgtggaa gtcggattcg ttgttggagt tactccgcaa accacaccga ctggttcagc
     5701 aatttcaatc aacccttttt ggacatcttc attgatcaca ccaactgttt tatcatgttt
     5761 gatattatgc caaatatatt cggacgcata catatttttg attgctttat cttcgtaaac
     5821 accgcggcct gtttcctcta cagccatctt cgctaatggc atatgttgat ccaaagctgc
     5881 cattgccatt tcatgcacga tatggtctac tttttcttga tcaaagcttt ccatttcttt
     5941 caatgctgca tttgcttttt ctgccaaatc atcaatcatt gcttgtacgt caattgtctt
     6001 cgttttttct ttttctatta ctttagccat cattatcctc ctaatgggtc atggttattt
     6061 gttaaataat tcacatgtat atcatacaat atttattttt ctatgtaaac acttttttgt
     6121 gatttttttc acagttattt ttaaatataa aattgcttta tttacaggtg tttgtataga
     6181 aaaatatata aagttattta ttattattta tatgacacac ccgattattc aatattgagc
     6241 aatatatccc atgctcttat ctctttcttt tttgaataaa aaatgaggta ggacatcttt
     6301 ctgccctacc tcgtctttaa ataagctttg atacttattt ttcttccttc tcttctgtct
     6361 cttccagcgt ttctgttgtt tcagttttta cttcaactgt ctcagctggt tcttctgttg
     6421 tttcaacagt agtcgttgca tcatttgtta cgacagtccc tggtttgacc gttttgattg
     6481 ctgcacgatc gtactcaagg aagatccctt cgcagtctaa aacaactgtc cgtttgtcat
     6541 tgtcgatttc tgaaacaact ccatgtaatc cgccgatcgt tacgactgaa tcacctggtt
     6601 tcatgctatc taacaagttt tgacgttctt gctgttgttt cttttgcgaa cgtgacataa
     6661 aaaaccacat tgctaatagc gcgataaaca tcacaagcat tggtaatgtt cccatttttt
     6721 tcacctcact aattctgtat ctacaaaaaa cactttagca gaaaaatgct gataacacta
     6781 gttttttact taatttttaa aagattttcc tttagaagct ttttgcgttt tctttattga
     6841 acccgtattc ttcaaaaaag gcttctctaa attcaagcaa attatcatcc atgattgctt
     6901 gacgtacttg tttcattaga ttcaacaaga agtataaatt gtggtaagaa gtcaaacgaa
     6961 tcccaaatgt ttcatcacat ttgatcaaat ggcggatata ggcacgtgta tagtttttac
     7021 atgtataaca atcacatttc tcatcaattg gacggaaatc atgggcatat ttcgcatttt
     7081 tcactactag acggccttga gaagtcatac atgtgccatt tcgagcgatt cgagtaggca
     7141 agacacagtc aaacatgtct actccacgga taacaccatc gatcaatgaa tcagcagcac
     7201 cgacacccat caagtaacgt ggtttgtttt cggggatcaa cggtgtagtg aattctaata
     7261 cacgattcat ttctgattta ggttccccga cagataaccc gccgattgag taaccaggga
     7321 aatccatccc gactagatct ttcgcgcttt gacgacgaag atcttcaaac cctgctcctt
     7381 ggatgattcc aaataatcct tgacggtctg gattagcatg agctttcaat cctcgttctg
     7441 cccatcgaga cgtacgttct actgattttt tcacgtagtc gtaactttca tcgaatggtg
     7501 gacattcgtc aaaactcatc atgatatcag agcccaattt attttggatg ttgattgctt
     7561 tttctggtga taaaaacata cgcgaaccgt tcaagtgatt tttgaaatgc acgccttctt
     7621 cttcgatatt ccgcatatca cttaatgaaa aaacttgaaa gccgcctgaa tctgttaaaa
     7681 tcggttgatc ccagttcata aatttatgca gtccgccagc ttcttctact aagtcttcac
     7741 cagggcgtag ccataaatga tatgtattac ttaaaataac gccagcaccc atttctttca
     7801 actcttctgg ggacattgtt tttactgtag ctaatgttcc tactggcatg aacattggtg
     7861 tggggaaagt tccgtgtggc gtgatcaatt cccctaaacg cgcgccagta tgtttttctt
     7921 tcttgattaa acgatagcga atggcaggtt gcgtcattca tttccctact ttctatataa
     7981 aatatcttga caactcccac catcataatc gtttcaagtg ctttttgcaa gttccctcgg
     8041 cttccttcta ctttatttaa tattcttttt tttatccttt ttttatgaat aacaaaaaaa
     8101 agaaaaacat tatgacagaa atattttttg atacatggta tattggtgtt attaaagaaa
     8161 aggagggaaa aatcatgcaa tcttctgcag aattaaaacg ccaagcaaaa gagagtctaa
     8221 aaggacgttg gggacaagct gttttactaa atctaatccc tacattgatt ggtattgcta
     8281 ctattcttct tattatgatt cctattatct tgtttgccac caccatatat gatggatcag
     8341 cgagcgtctc agaagcgaca acttcaggag gcggtagttc aggaggcggt ggcggaatta
     8401 tttccagcat cattagcgct ttgttcatga gcggtatttc ttggacttat cttgatattt
     8461 tacgtggaca aaaagatcag atcgaaccat tcaaagatgc atttcgtgga ttcaaaggtt
     8521 tgtttatcgg cggagtgatc agcttagctg tgctgatctc gatctttaca acattatggg
     8581 gtttgctatt agttattcct ggaatcatta aaagctattc ttattctcaa agctatttta
     8641 tttactacga tatcgtccaa gaaacaggac aaacacctaa agtactggat acgatcactg
     8701 caagtcgaaa attgatggat ggttataaag gacaactttt ctggttagat ctttcattta
     8761 tcggctggca tatcttagca ttagcaactg ctggtattgg ttatctatgg ctcagcccat
     8821 acatttctgc aacaaaagca gcattttatg aacaattgcc aaaagatatt taaaagagag
     8881 tgtgacttgt gaccgagggg gtggcaggag aacaccgttt atcgagaggc agtaaaagaa
     8941 acattcagcc cattagcaaa aaggaggtgt gacaacattc atgtcacacc tcctttttgt
     9001 atagttccag taaaaagaaa atcaacttag aaacagttaa tcattcctct tcttctgctt
     9061 ccggtaatcg atggaacttg atcagttcat tcaccgcgat tggtacgata gataaaatcc
     9121 ctaccaagaa ccagtgattc aaactgatgt gtactaggcc gaatagttct tgcgtaaatg
     9181 gcagcaaagc aacagccgtt gtaatagcta atgccagtaa cgccatttct accaaagctt
     9241 tattggtcgc taaattgact ttgaagatcg attggctgct gcgtacattg aacacatgca
     9301 gaatcgatga ataagctaag atcaagaatg caacagtttg accgacatgc tgacttgcgt
     9361 ctacccatgg gctgatagta tcgacataac tacctaaata ataaccaaac aaggttacga
     9421 tggtgaagac ccctgcattt atggcaattt tttgcaataa acctcgagca aagatccctt
     9481 catttttcgg aatgggtggc tgatccatga tgccgtgttc cgctggctct cttcctaaag
     9541 caaatcctgg aagtccatca gcaactacat tgacaaacag tagttgcaca gctgtaaatg
     9601 gtgctcccca tcctaacagc atcgcaatca aaacaataaa gatctccgaa atattacagc
     9661 ttagcaaaaa gttgatagct ttacgaatat tctgataaac cgaacgtcct tgactgacag
     9721 cgtctacgat cgtcgcaaag ttgtcatccg tcaaaatcat atctgcggca ctttgcgcca
     9781 catctgttcc tgtgatcccc atggcacacc caacgttact tgctttcaac gctggtgcat
     9841 cattcacacc atccccagtc atcgctacga ctgcacccgt acgttgccaa gatttgacga
     9901 tccggatctt gtcttctggc gttacccgag catagacaga gagagctttg acacgcgcat
     9961 ctaattcttc gtctgataat tgatgcagtt ctgatcctga aagtgcttct gacggatcat
    10021 tcaagatacc taattctttc gctatggcac tggcagtcac cacatgatct ccagtgatca
    10081 tgactgtttt gatgccagcc tttttcgctc gcttgattgc tcctttactt tctggacgtg
    10141 gtggatcgat cattccgatc agaccaatca aacgtaagtc tttttccagt gcttcagaag
    10201 aaatatcttg cggttcttcg tcataagtag cataaccaac agcaatcact ctcagtgccc
    10261 gtttaccaaa gcgatcatta acgatcgccg cttgttctac atcgcctgaa ctaaagcgcg
    10321 gagcaagaac atcgaatgct cctttggtga ttgagatgta tttttcgccc atttggtgaa
    10381 ctgttgtcat catttttcgt tcagaatcaa aaggaagctc gtttactcgt ggatattttt
    10441 cttctaattc tgcctttgta tgataattct cttcaacagc ccttacgatg gctacttctg
    10501 ttggattacc tttgataaca aggtcgtcat cttcttgctc gaccgtcaca tctgtacata
    10561 gtgcagccat tttcaatatt tccatcgcgc tgttcgtcat tgaatcttcg atattcgtta
    10621 cttcatcttc tttgctccat acccggcgga cgcgcatttc attttgtgtc agcgttcctg
    10681 ttttgtctga gcagataaca ttagcggttc ctagcgtttc aactgctggc aactgtcgga
    10741 tgatcgcatg tttcctcgcc atcttctgca caccgtatgc aagtgtcaac gtaacaataa
    10801 cagtcaaggt ttccggtaca gctgcaacag ccaaggaaat cgaagtcatg aacatctcaa
    10861 ggagtggttc tccttgcagt tcaccaatca caaatactaa agccgcagcc gctaaagcga
    10921 tcatactgat tcgtttgcct agctgattca atcggacctg taaaggtgtt ttttgcatag
    10981 tattttcgtt caaaagatcc gcgatcttac ccatttctgt agccatgcca atggcagtga
    11041 cgatcgcttt cccacgacct gcagcaaccg tacatccttt aaataccata ttaagttggt
    11101 cacctaatga ctcatcttct tcagcaataa atgctgcatc tttttcaact gcttcacttt
    11161 ctccagtcaa cgccgattct tctacacgta attgtgatgc ttcgatcaaa cgggcatcgg
    11221 cagaaatagc atcaccggac tctaaaacaa gaatatcacc cactaccagt tgctctgact
    11281 caacagtggt cactttgccg tctcgtatga cagttgccgt ttgtttattc atatcttgca
    11341 aggattccag tgctttttct gcgtttcctt cttggacaat cgccaatacc gagttgatca
    11401 caacgatagc gatgatcagc agtccttcaa ataaatcccc atgttctgta gcaaatgcgg
    11461 tataaaagga aatcaccgct gctacaagaa ggatgatcgt tgtaaaatcg gacaagcttc
    11521 gaaagaattt tttgatcatc gattctttcg gcgcctcatc gaatttattc aatccctgct
    11581 tttttcgccg ttcatccact tcttgtgaag acaacccagt atctggatct gcttctgtta
    11641 ccttctttac ttcttctatt gtctgcttgt attcttccat cctattcctc ctttaaaatc
    11701 ttcgtacaaa aaaaggtact tattttacta taacatcctt tttttattta cttcaaataa
    11761 agggcttatc gattatttgt taagaaagcg taaaatttaa agtgcttata tttgcaaacg
    11821 ctaccaaagg atgctattat atagatgtaa ggaaggagga taccatcaaa tagacagaag
    11881 aatttctcga tagaacagtg taagcaaaca aagttgttag aagtacaggt ttcacccaga
    11941 catgcgtgta gagtacaaac ctataaatag tgaatgcgta tggatgtttg gatcacgaag
    12001 tatccgaaac aagaagtaat gcgatacgta acaattgaat aacgtaaacg tctgaaaatt
    12061 gaataggaac aagagatgtt tcaaatgttg aagatgtaac gaaaacaaaa tttttgttta
    12121 acatgaagaa attcaacacc gtgctttgca tgtatgatgg aaagttacaa tcatttctgt
    12181 ttatttgaat ccttccgagg tacaagaaag ccgagcttat cgagagctcg gctttttctt
    12241 tgtcataaaa tctttgtaaa gcttttttgt tattcaaaac tagcggcttt tcataacctt
    12301 atttcacgaa catcgcatct ccaaaactaa agaaacgata gcgctcttca atcgcatgct
    12361 ggtaagcaga taaagtcaat tctcttcctg caaaggcact aactaacatg actaaagtcg
    12421 attttggcaa atggaaatta gttgagaaag cttctaccac tttgaattca tagccaggcg
    12481 taatgaaaat atcagtccat ccgctgtctg ctttgatttc tccattaaat ttcgttccaa
    12541 tcgtttctaa tgttcgaatt gaagttgttc cgacagccac gattttcccg ccatttttac
    12601 gtacttggtt caatcgctca gccgcttctt ccgtcaaacg gtagaattca ctatgcatat
    12661 ggtgttcttc aattttatct acgctgacag gtcggaatgt acctaaccct acatgtagtg
    12721 tcagatagac taattcaaca ccctttgctt cgatctcatc aagtaattct ttcgtaaaat
    12781 gcaatccagc tgttggcgct gcagcagaac cattttcttt cgcatagaca gtttgatagc
    12841 gatctgggtc ttccagacgt tctttgatat atggaggcaa tggcatttct cccaatgatt
    12901 caagaatctc tagaaaaatt ccttcatact caaagtcaat gatccgtccg ccgtgttcca
    12961 attcttcttt cactactgct tgcaatctgc catcaccaaa agagattctt gtcccaactt
    13021 tggcacgttt cgcaggtttg atcaatgtct cccacgtatc tccttgtgta ttcgttagaa
    13081 gaaggacttc taaatgcgca ccagtatctg gtttttctcc atataaacga gcaggcagaa
    13141 ctcgtgtatt attcataact agcgcatcac caggctgtaa ctcttcaatg atttcatgga
    13201 aatgtttatc ttccatctct ccagttttcc gatccaaaac aagtaaacga gaatgatcgc
    13261 ggtcttttaa tggtgtttgt gcgattaatt cttccggcaa gtcaaaatca aaatcttctg
    13321 ttgttaacat atcgtcactc actttctatc atgtgcttca tcattctatc atgtttttcg
    13381 ttctgttggc aaaatcagca ctttttcact tctatttttt gttttcctaa ataaaaaaac
    13441 taccctattt gtattttttc attgttttag gcatactagt aatagatagt tcttcattga
    13501 aaatagaaaa agaggtggca ccatgattga atttcaaaat gtgtcaaaaa tttataaagg
    13561 tggaaaagtc gctgtagagg acgtcaatct ttcatttgaa aagggtgagt tcatttgttt
    13621 tatcggtacg agcggaagcg gaaaaacgac gacgatgcgg atgatcaacc gaatgactga
    13681 tccaacacaa gggaaaattt tgattgatgg aaaatccatc caagaaattg atccagtgga
    13741 attgcgacgt cagatcggct atgttatcca aagtattgga ttgatgcctc acatgacgat
    13801 ccgtgaaaat atcactcttg tccaaaaatt gttgaaagtc agtcaagaag aacggaataa
    13861 aacagctgaa aaaatgattg atcttgtgga attgccccgt gagatgttag atcgctaccc
    13921 acatgaatta tctggtggtc agcagcagcg tattggagtc gttcgtgccc ttgcagcgaa
    13981 tcaagatatc atcttgatgg acgagccatt cggtgcgctt gatccaatca ctcgtgattc
    14041 cttgcaagac cttgtcaaag atttacaaga gcgtttggga aaaacgatcg tatttgtaac
    14101 ccatgacatg gatgaagcga gtgaactact caccacttag ctaaacctga cggttcttaa
    14161 cgcttgaagt gggagcttct tgggaataga gcatacttga tagcgtattt ctttactaac
    14221 agcggtgtct cttatttacc aagctatccc cgtagttcct acggttcttg atgattggat
    14281 ctaagccaat cccatagaat gtagtcttag accttcggtc agaatattga tactagcatt
    14341 gatatcacga tcatgatgag tatgacaaac aggacaagtc cattctcgaa tttcaagaga
    14401 tttcttgcca tctttatgtc cgcactctga acaaatctga ctagacggaa accatttatc
    14461 tactttgatg atttttcgtc cataccagtc agccttgtat tgtaatttag tcacaaactt
    14521 tgaccaagaa acatcagaaa tacttttagc taatttatga tttcgcaaca taccttttgt
    14581 gtttaagtct tcaatacaga taatatcgtg atttttgatc atttctgtac tcaacttatt
    14641 cagaaaatca gtacgttgat tcattacttt ttcatgcaat ctagctactt tgcgtttttg
    14701 tttttgataa tttttagctt caaatagatt ggtaccttta tttttagcca ataaagcacg
    14761 cctagacaat ttgcgttgtt cacgctttag tttcttttcc attttggacg tgaatttatt
    14821 attatcaatt ttttgtccat cagaaagaat cgcaaagtcc ataataccta agtcaatacc
    14881 aattgtggaa ttagttttag gtaattcgat aatttcttct ttacacaaca aagaaatata
    14941 gtatttaccg ctagaatgac gtgatattgt agcagatttg ataatccctt ttggttgtct
    15001 atgaagctta attcttacta atgacttcaa tttaggaact ttgatgaatt tactatcaat
    15061 caaagcaact gtaccatttt gattattcgt tgtataactc tgaacaggat ttttcttact
    15121 tttgaaacgt ggaaatccaa cggatttatc ccgaaaaaaa ttcttgtatg ctttatctaa
    15181 attaagttgg gcattggcta aagcaaggct atcaatttct ttcaaaaacg gaaattcttt
    15241 cttgtattta gctggtgtcg gaaaagtcat ttttttagaa gaatcatttt taacttcttc
    15301 atacgccttt tttcggtcat caagcattag attgtagacc ttacggacac aaccaaaaga
    15361 tttggcaaag aagatttctt gttcctctgt tggatagatt ctgaatttgt atgcttttag
    15421 ttgttccata aagttcacct actttctatt tatgattgtt tccttgattt tggatatact
    15481 tcttaatcac atcaattggt gcgccaccag ttgtcagaag acaaaaactt ttagaccaga
    15541 acatttcttt ccaaagaaat tgtttgactc ttggaaagtc acgttttatc aatcttgagc
    15601 tggcactttt ataggcattg atgaattttg tcaattctgt tttaggttga gctttgaaca
    15661 taatatgaac gtggtcttta tcatgattcc actccactaa agtaatgtga tacgattctg
    15721 aaattctttc aaaagtagtt ttggcataat cagatatttc atcatcaatc acttgtctac
    15781 gatatttcgt tactaaaaca aggtggtaat aaagaagaaa tactgaatga ttatttgtat
    15841 ctaattccat gttatatcaa ctcatttctt gtatagactg attgtaacat ggaacaaaat
    15901 aaaaaggcaa tacgccttag ttgtcggtct tcgagttacc aacggtaacc ctcataccga
    15961 acggcattca tcacccacct atagaggatg ggcgacttct gcctaattct gttaaactag
    16021 caagccgtat cgccatcatg agtgaaggcc gtgtgatcca atttgataca ccagaaaata
    16081 ttttacgtca tcctgcaaac gatttcgtag aagagttgat tggagaagat cgcctactac
    16141 aagccaagcc aaatgcgaca agagtcggcg aagttatgct aaatacagca atcacgatta
    16201 caccggaaaa atcattacaa gaagcaatca aactgatgag ggaaaaacgt gtagatacgt
    16261 tgttagttac cgataattcg aatgtattaa aaggatttat cgatgtagaa acgttgaata
    16321 aaaaacgagg aaaagtatcc agtgtcggcg acattttgaa taaacatgtt ttttacgtaa
    16381 aagaatccgc ctatcttcgt gataccttgc aacgcatttt aaaacgcggg ctgaaatacg
    16441 tgccggtcgt tgatgaacag aacaaagtcg taggtatcct gactcgtgca tcattagtgg
    16501 atatcgtcta cgatgtgatt tggggagaag atcccgcaac tactgatgtt gcagagtcag
    16561 ctactcctga agaatctaag gaggtctgac ctatgcagca gttttttcat cagcacggtt
    16621 cagaaattct ctcaaaaggt tttgaacatc tttatatttc aggacttgct ttgatcattg
    16681 gtatcatcat tgctgtaccg cttggtgtct tactgacacg ttttccaaaa gctgccacga
    16741 ttgtgattgg cttaaccagt gccttgcaga caatcccttc tcttgcttta ttggcattga
    16801 tgatcccgct atttggcgta ggtaaattac ctgcgattat cgcactcttt atttattcat
    16861 tattgccgat tttacgtaat acgtacattg ggatgaaaaa tgtcgattgg aattatcggg
    16921 atgtggcaaa aggcatgggg atgactgagt tccaatccat tttttccgtt gaattgccca
    16981 ttgctatgcc aacgatcatg gctggtattc gtttagctgc cgtttacgtg attgcatggg
    17041 ctacacttgc ctcttatatc ggcgctggtg gtttaggcga tttgattttt agtggactga
    17101 ataattacca accagatctc attttggcag gtacgatccc tgtaacaatt ttagcactat
    17161 tggctgattg gcttctaggt ctcttggaac accggctgac accgatcgca cttagagagg
    17221 agaatgaaga atgaaacgta tactaaaaat gaccatggtt cttttctctc ttcttatact
    17281 tgcgagttgt tccttccctg gtcttgccag caatacagat gaagacacca tttcgatcac
    17341 aggtggaatc acttcagaag cacagatctt agcaagtcta gttgccggaa tggttgaaca
    17401 ttatacagat aaaaataccg caatcatcaa caatctggct actacaacta tcaaccatca
    17461 agcgatgatg aacggagatg cttcaatttc agcggctcgc tacacaggaa cagatttaac
    17521 gactacattg aaccttcctc ctgaaaaaga tccgaaaaaa gcgtttgcta ccgtgaaaga
    17581 tgaatttgag aaaagatacg gtcaaacgtg gttcccgtcc tatggttttg aaaatacgta
    17641 tgtctttctt gttcgaaaag acaccgcaca aaaataccat ctatctaaag tcagcgatct
    17701 gaaaaatgta gcggatgaat tagtagctgg tgtagatact tcttggatca atcgtaaagg
    17761 agacggttat gacggcttcc aagaaactta tggcttctcc ttcaattcga tattacctat
    17821 gcagattgga cttgtttatg acgcagtcga agcaggaaaa atggatattg ttcttggcta
    17881 ctctacggat ggacggatcg ccagttatga tctagtcatg ttggaagatg atcgtcaatt
    17941 cttcccacca tatgatgctg ctccagttgt agacaacaag atattagctg atacgcctca
    18001 tttaaaagaa gccttaaata agttaggtca taccatcagt acggaaaaaa tgcaggaatt
    18061 gaactacgaa gcagataata atctagtgga accatcagta gtagcacaac gtttcttaca
    18121 agaaaaccac tattttgaag ggaagtgaag caattggata aaatgaatgt ctttcaacaa
    18181 tttttctatt atttccagga aaatggctcc tatatctttg cacaatttat ccgtcacttc
    18241 ctgatttcta tctatggtgt cctctttgca gcagttgtcg ggattccggt tgggatcatg
    18301 atttctagga gacgtaaatt agcaaactgg gtgattcgtt tggcgaatat catccagacg
    18361 atcccttctc tagccatgat ctccatttta atcattggat taggcctggg agtcaatgtc
    18421 gtgattgtta ctgtattttt gtattccctc ttaccgatca tcaagaatac gtataccggg
    18481 atgatccaag tagacaaaaa catccttgat gtcggcaaag gcatggggat gactgctaga
    18541 caacgactat tcatggtaga gttaccactc tctgtttctg ttatcatggc aggcataaga
    18601 aacgcgttag ttgttgccat cgggataacc gcgatcggtg cattcgtcgg tgctggtggt
    18661 cttggagata tcattatccg aggaaccaat gcaacagagg gcacatcgat tattttagca
    18721 ggtgcattgc caactgcatt aatggcgatc atcacggact ggcttttagg tattttggaa
    18781 agacggctag atccagccag ccgtacatca cgctgatgtt attgtaaaaa acaaaagctt
    18841 ctgcgaccat ttgttggtcg caaaggcttt tttagttctg tcatttttaa ggcaataatc
    18901 cactctgatt cttccctcct tatgggcaaa gagttgcttt tcttagctat ttatccattc
    18961 cgtatactcc aacttcatac tgccaacggg ttcatatctg catccaccga ctaagttttt
    19021 ttcttatccg ctaaggcatt ttgccaatcc attttcccat cactcgtcat ggaattcata
    19081 ccacatgatc tctaaatact cgtctgcttg ttctttgaat tgggcatcaa ttcttacatc
    19141 ctttggcgtg gctttcattt aagccttttc catcagtcct cgattgttcg atgccttcag
    19201 ctgcatcatc aaaactggtg actgccgtat cggtaacttc gatcatcttt tatacaatcg
    19261 ggaacttgcc atcctcatcc ttggctaaaa acatatctag ccattccagc ttctcgccat
    19321 gggaggtttg cggttcctaa aaccggtaca cgattcttat ggactgcatc cgtcgcaact
    19381 agacttggcg atacgatgat ccttcaccag aagagcaccc ccgtaaacca attgatcgat
    19441 atattgccaa taagaaaaga cattggcgta aaagatatcg atccctcgtg atgcattgcc
    19501 gttgatactg ctattcatgg ccgaaagcgc cacgacttta acttcttccg tttgagtgac
    19561 attcatgttc ggcaatgtcg ctttggatac ccgctctgct aaaggaacga cactggtatt
    19621 gtatttcgta tctgtatctt ttccaaaaga ccatgccaac gaatcctctg ggaaccaata
    19681 agacgactcc ggttgattgt ccattgcttt tttcaacata cttttggctg tttctcgata
    19741 aacgacattt ccaattgtct tcgcctcact ttggcgataa tcgatggtcg ttgccactgc
    19801 caacactaac aacgatgctc caattttact gattttcctt gtcacacttc ttcctccttg
    19861 ttttacataa acccgtcaac attccattcc taaactcaaa caatgaccct tcaaaggtgg
    19921 agatatagga acaaattaaa gaaatcatgc aataaatcca agaaggttgg ttttagaaca
    19981 aaaaaagagt ctcctttttg gggagactct ttgttaacta tctaaaaagg ttggctcttc
    20041 tcacttcact cataatgtgt ccaggcagaa taaatttcta caactttatt ttcctcatca
    20101 actttgtaaa ccactcgatg ctgtctattc agcctgcgtg agtatctgcc ttcatgtgta
    20161 ggtctcagct tttcaaaaga ctgcgtgggc atatatggat cttccttcaa tgtctgaatc
    20221 acttcttcaa attgtttctt taaattcgtt tgcttgattt ttcttaaatc cactttcgca
    20281 gagtttttga ttgcgactgt atagttactc atcaaagagc ttcccaatca atatcatcga
    20341 tattcgtaaa gctactgtcg tctttttcgc ggtctcgtac tttatctaaa gtacctgttt
    20401 gctcaagaaa aagggtttct tgaatcgctc tccagtcttc cagcccaatc aatacagcat
    20461 tgtttccact acgatcacta ataatctcga tttcagtatg attttcattt acctctttca
    20521 ataactgata aaaattttta cgagcagtgc taggattcat cgttgtatta gccattgtct
    20581 ctcctccttt ttctgatata attatagcgt acttgattaa gtacgtcaaa aaaatacaat
    20641 aaagcactta aattcagcaa acttttcctc ttttttacat agagaaaaag accccttttt
    20701 agggaggatc tttgtccacg ctcacttctt actcctttac gactagcggt agccaaacgt
    20761 aaagtaattg gtaacaacgt atcatcttta gcaaaggtcg aatccaaagc ctgtgagtct
    20821 atgcaacaac accaatacac gaaggttcct cgttgcagtg tgacttgatt gatatcttga
    20881 ataacctgag gatacgcacg aaagatttgt aacggttatt caaaactgat tttggccgtc
    20941 aagtcttcta ctgcctcaaa aatgattgcc tctttcgtct cctgtcattc atgttcacta
    21001 tcgatttgat acttgcttag accgttgggt ttgtgaatca ccaattaaaa atggcactga
    21061 gttatggtaa caaaaaatgg tcacttgacg aggctgagat tcctacttat gaagacacat
    21121 ggcacttaag agtcgaggta aaggaagaag ctgaaaatat aggaggctgt acattatttg
    21181 gcaaaggatt cggaaattat gatcaagaca tcaaaatcaa aatgttttac agctaaatag
    21241 gaagaataat aacatttcat acgctgttcc catctttaat ggcttataga gggcaccttt
    21301 agctgagaat aagacaaaac agaccctcta gcttcaatta agagctagag ggtctgtttt
    21361 tgattttaaa acttggttta tttcttcaaa tggtagctat aggtgctgac aacgatattt
    21421 tcacgccaag acaatcgcaa tcttaaccgc aaacttgttt ggttatggag aatattctgc
    21481 cagcgtctgt ttggtacaaa ttgaggaatc aacacagtag ttgtatagtt ttgtttcgct
    21541 gcatttttac ttacgatatc tacataacgg ataattggat tttcaatcga gcgataagaa
    21601 gagtggacga ttgaaaaacg gacatctggg aaatgctttt taaattctgc ttcgatttct
    21661 ttttcttttt cgacatcttc gtctagcgaa acatgcatcg caacgacata atcaccgatc
    21721 gaacgtgcgt aattcaacgc accgatattt acccgtgtca cattcccgac taatacaaga
    21781 acggtattcc cgtcataatc atgtagtttt gcatcatttt ctaaacgaag ctgttctgct
    21841 acttttttat aatgatcatg gatcttataa aaaatgaaca taacgattgg cataatgatg
    21901 aagaaaggcc aaatgtcccc taaccgatag acaaacaaaa tcgcaatgat tgcatatgag
    21961 atgaacgcac ccgtaatatt ggcaatcgat ttgcttaacc atctttttcc ttcttttttc
    22021 catttgacga ccatccctgt ttgagataaa gcaaatggaa tgaacacgcc gatagagtat
    22081 aacggaatca agcgttctgt tgagccatgg aaaataaaca gcaatacgat cgaacctagc
    22141 gctagtgtga taatcccatt ggaatagcct agtcgatccc cacgatcttg atacatgtga
    22201 ggcatgaatt tatcttttgc cagattgtat gcaagaactg gaaaagcaga aaaaccggtg
    22261 ttagcagcaa ctgctaaaat cagcgctgta gcaaattgaa ggacgtaata caaaatacca
    22321 tgtccaaaga cagctttacc aatttgagac aaaacagtga cttctttttc aggaacgatc
    22381 ccataccaat agttgataaa tgtgatcccc acgaagaaga aacctaagat caatgccatc
    22441 atcgtcaatg tagcagcggc attttttgct cttggcttct taaagaatgg tacagcatta
    22501 ctaatcgcct ccaccccagt taaagaggaa gaaccagaag aaaatgctcg taaaatcaaa
    22561 gcgatagaaa cacccggcac agccgctcct ggaagtgcag tagcttgcaa tggcacagca
    22621 cctgtcacga tattatataa accaacaacg atcagtaacg agatcacaag gataaatgtg
    22681 tacaccggaa ataataggaa cgatgcagat tccctcagcc cacgaagatt cagcatcatc
    22741 agtagcaaaa cgattgtcac agaaatagcg acttgatgac cgtagagtgc tggcaccgct
    22801 gatgtgatcg cttcagcacc tgctgagaca gatactgcta ctgtcaacat gtagtcgatc
    22861 aataaagagc caccggaaat caagccagca ttctttccaa gattctcact gctgacgaca
    22921 tatgctcccc cgccatgagg ataagcatgg atgatttgac gatatgatag cgttaatgaa
    22981 atcaataaaa taataacaaa agcggcaatg ggtagcgaat accagatggc tgcagcagac
    23041 aaagcgacta aaacgacaac gatttgttcc gtaccatatg caatagatga taacgcatca
    23101 gacgacaata atgccaaagc agcaaatcgg gttaatttgt gctcatcatt ttcagcagat
    23161 tttaaaggct tacctactaa caaccttttt aagtaatcca atttctaaac tcctttacac
    23221 acaattttac ttcaagtttt atagtcgaaa atttatagta aacaagatgt tatagtacgc
    23281 tcactgacct taaaagtcaa taaactttaa gaaaataatt ggaaaaaaac agaaaaatat
    23341 caagcgcttt ttcaaacgct ttaatacagc aaaaatctaa cattttttta tgggcttttt
    23401 ctttgaattc tataataaaa ggatagaact tgacttagaa aatcaagttc tatccttttt
    23461 gatatcttaa cttttggaag agagatgtaa ggctgctttc tacccatcat tcttactact
    23521 cgaagcatag cgcagttgtc acaacctctt gataaacggt gtttaaaagc ttgcatctgc
    23581 ggtaataagc tcaaccaaat taaaaacata agaagctgtt tttatttggt cgttcttatt
    23641 acttgatgca gagcagcttt tttacaacct cttggtacac ggtgttcaat cagctgaccc
    23701 tcggtattag ctcaaaaaaa cggcaaaata tgaggaacta tttttccatt tttttctcta
    23761 atactcaggt caaaacactg atttcacaac ctcttttttt aatgaaaaat atggctctca
    23821 tgcgccgctt ctttgaattt cgtcattttt tcttcgatga acggatagat tgccgttcct
    23881 acgattccaa agacaacaaa caaaccgatc atgatccaga ttgctttcgt agcatttggc
    23941 caataaattc ctcctgcaga ttcccgtaac aagtttaccg catgagtaaa tggcaagaac
    24001 ggattgatca tttggaagaa tttccctgag acttggatcg gatagttccc gcctccgcca
    24061 gagatcgaca gtactaagat gataatagcg atccctttac cgacattatc gaataatgca
    24121 gccaagacat agacgatcat catgaacgct aaggcgatca agacagcaaa tgacacgctg
    24181 tagaccggat tttggacatc tactcctagt aagaaaatat tccctaatgt aacgatcaag
    24241 ctttgcgcaa tcgccattgt caaaaatgtc agcatacgag caacgaattg ttctcgtttc
    24301 gtaaaattgt ttcggtcttt ctttcctaaa tagtattctg tcgtagcaac acttgaaaga
    24361 agaacagcgc cgacccacag acatagtgca gtataaaacg gggtgctagc tgaaccgtta
    24421 tttgcgattg gataaagcgc attggtttgt agctcaacag gttgtgtaaa gaagtcactt
    24481 tcttttgttg cgtctagttt caataatttg atgacttcgc ctagatcgac ttcttgttcg
    24541 ccttttcgga tcgcgtctgc tgctttttgg ataccagctt tgatatttgg ccagtcattg
    24601 ttgatcaagt ccgcagcagc gttcacagct gtttcgactt ctggcatttt ttcatttact
    24661 gttgtcaatg taccggtgat ttcatttttt agtgctggcc aatcattttg gataaaatca
    24721 gcggccaatc ctaatttttg ctgaatgatc ggtaattcat tgttgtatag gtctgcccct
    24781 tcattgatgc cattgacgat ggtatccata tttccattca gcattgtatt ggcatcatgg
    24841 atttcttgtc caattgcagg catttctttt tgatattttt ctaaaattgc cactgcattc
    24901 gttacagttg ctttcgttga gctgagaagc gaatcaaagt cgatctggtc cgctttgctc
    24961 agtgcgcctt gtgcagtccc aatcgtatcg atgacttggt ctagtagaga agtgacagtg
    25021 gaactgattt gacctgtatt gataccagca atgatgccat tgatattatt aacaacggca
    25081 tcaatttgat ctagcaattc atcaatagcc ttcgtgtctt cattttgaac agctgtgttc
    25141 aaagcagata ggcggttttg cagattgctt agcaagggtt ttaattgatt tagctgatca
    25201 ataattggct gtaatttcgt atttccagca cttgtttgca atttagtcag gaactcgacc
    25261 agtttatcga ttgcattttg ttgttgagat attccgtcaa taaagccgtt caatacattg
    25321 ctgatgtttt tcttttcatc atcagtcagc ttaccatctt caatagctgt tcttacagta
    25381 tctattaacg aacctgtcgt tgttgccact tgtccaattg acttcaatgt aacatctaca
    25441 ctgtttgtga tgcttggtat cgcatctttc agctgagagg cacctgattt tgtttggttt
    25501 gctagatcac ttgcctgatt ttctaaattt ttcacatctg gcaagatatc ttgtacttgt
    25561 tggatgatcg tcaagccttg ttttgcttca tcgattcctt ggttcattgt ctcttggatc
    25621 gaagcaaaat cgccgtcgat ctctgctagt tgcttaccgg cattttggat ctctgggatt
    25681 ttttcttgca aatcaaggat gatttttgct tgatctttca actcaggcat tttgtcattc
    25741 aatgcaacga ctttttcacc catctcatct actttaggga tgtaatccac gaattcattt
    25801 gctttattca gtttttcctt gatttcaggt agttgacttt gtaattcgag gacttgtttt
    25861 gtgtagccgt cgatcgtgtc caaattttca tctgttgata aaatcatatc tttaacttta
    25921 ttgatactta ctaggttcgt atcgatgtcg taacctatct cattgaatac tttcaataaa
    25981 gtcgaactgg ctgttttgat aaattcattt gtgatttgcg attggatcga acttgctcct
    26041 ttatcggtga ttttcggtgc aatcgcattg attttttcat ttaccgtata ttcgattttt
    26101 ggtttcttga tatcaccact agtaaaactc agcagatctt ctgagaaatc ctttggcaag
    26161 taaatacctg cgtaatactt tccggaacgg actccgtctt ctaattgttc ttttgaatca
    26221 acgaattgcc atcctaattg tttattttta tgaagcgatt cgatgacttg ctccccaatg
    26281 gccacttctt taccttgaaa ctctgctggc ttgtctgcac tgtaaacagc aattggcagc
    26341 tctccagtat ttccatatgg atcccataat gctttgatgt taaaccacgc atatagcgaa
    26401 gggatgatca tgatcgcgat gatcagaagt gttgcaatcg ggtttttgaa aatccgtttc
    26461 cagtcaagca aatataatcg aagcgtattt ttgattgact gcatagttct cccccttctt
    26521 cttttttcag ctgaattact ttaccatgta tttcatactt ttttcaatcg gcttttttca
    26581 aaaaagtcga atttttggac atatcacggc aattgtctca ttgtaatctc ttacatattg
    26641 agaaataatt aaggattaca gcctttactt tatcatgaaa taaaagggaa agataatttt
    26701 atgccaaagt ttttatctat tatacgtata cgcaaaaaag ctaaaacatt ttttgtcttt
    26761 gcccctacaa aaatgtttca gcttttttcg ttttttattc ctgtatttct tatttttcga
    26821 atgacaggat gattttccca gcaggaggat gtccttcaac tagctgatgt gcttggatga
    26881 catgcttaag tgaagcagac agattcattg aaataaaaac atgaaaggct cctttttggt
    26941 aggctttgat tatgccagca aaggcttctg catctagata ttcctttctt ggaacaaacg
    27001 attcataaaa gccttccttt ttttgccgca aatctagatc tgggaggtca tttaatgcaa
    27061 catacctgcc gcctggtttc atgatctgga tgccggtttc tcctttgata cttcctttcg
    27121 tcgcatcgat tacaaggtct gcctgatcag caaattgcag acctggattt gttttatcat
    27181 aagcagcaaa tgctgaagct cctaattttt ttaccttttc ctcattttta ctggatgcac
    27241 tggttaagat tcggattccc ttttcatgga gaagctggat cagacttgac ccgaccgcac
    27301 ctgatgctcc tagtatcatt acagtatctg tcggctggat ttccgtcaaa tggttgatta
    27361 gattataagc cgtaattcct ggcgtgacca ttccggctgc ttcttcccaa ctcattttat
    27421 ctggaatttt tgctactttt gctgatggca acacgacttc ttctccgtaa gtcccgccga
    27481 ctgcatggac agctactcga tcacctacat gaacagttgt gacatctgaa ccaatctctg
    27541 tcacaatacc agcgccatca ttacctggta cataagggaa tttcaatgtt cgtatctctt
    27601 tcatttctcc taaacgcaag gcaacatcat aaggattcac actgaatgct tttatttcta
    27661 cacgaacatg tccagaaccg acttctctgg gatgagcatc gatttcttca aaaacatctt
    27721 gtgcttctcc gtaaccgtta attgcaaatc ttcgcatggt caccatctcc ctttttcttt
    27781 aagtttacgt ttatgtcttt attttgacaa aaaaaatgtc ttttcgtttt ggcgcatgat
    27841 tcaaaacaaa atagttgtct tttttcgcgt aacgtgttaa attatttatc taaaagcgta
    27901 aagattacga tttacgctaa taaaaaataa ttggaggaat ttgttgatgg ctaaaaaatc
    27961 aaagattgcc aaagcaaaaa aacagcaaga aacgattgaa cgctatgctg ctttacgcca
    28021 ggaattaaaa gcgcaaaaag attacgaagg cttgcgtaaa cttcctttag atgctcgtcc
    28081 agaacgattg aaaaatcgtg atttaatcga tggacgccct cgcggataca tgcgtaaatt
    28141 cgggatgtcc cgtataaaat tccgtgaatt agcacataaa ggtttgattc caggagtaaa
    28201 aaaagccagc tggtaatcca agtctggctg taatgtaaag gaggagggcg catggaccac
    28261 tccttggatc atcaaaaaag atacgttcgc ttcttctagc agaaatgctg gtactagaag
    28321 cagacgtatc tttttttacg cacagctggt ccttttttat atgtaaaggc tgcatggtta
    28381 cttcgctata tttatttagt aacaggagtc agtgcttcga tacccacact aattttcaat
    28441 gctcggtcaa cttctgccat aatgggtcga tccaaatggc agaccttttc tttcaatctt
    28501 gatttatcga tcgttctgat ctgctccaac aggataacgg agtctctttc tattcctgtt
    28561 ccagtagctt tgatcccaat gtgagtcgga agcttaggtt tagccatttt tgccgttatg
    28621 gccgcaacaa tgatcgtcgg gctaaaatgg ttacctagat tattttgaat aaccaaaact
    28681 gggcgtgttc cgccttgctc cgatcccacg actggagaaa gatcagcaaa ataaatatct
    28741 cctcttttta ccataggatc ctccttattc ttgatattct cttggtatcc gctgtcctaa
    28801 tccgcaagcc acttcatagt ggatcgtacc taattgatct gctatatcct gcatagtgat
    28861 ttctttgtct gcatttttgc cgataagcgt cacttttgtt ccgacaggaa attcttgagg
    28921 caatcggatc atcagttgat ccatacatac acgcccaatc gtttcacagt agttcccttc
    28981 taccaataga gaaaaaccct gcatctttcg tggccagcca tctgcataac cgatcggtat
    29041 cgttccgatc cactctgctt caggagtgat atatgtttct ccatagccga ttccttcacc
    29101 tgctgggagt tttttgactt gaatcaattc agaaaccagc tcaagtgctg gctgcaatgg
    29161 ataaacttcc ggtagtgcgt gcccagaggg attaagtccg tacattgcta ctccataacg
    29221 aatcatattg ccgattgttt catcatgcca taaagccgtt gcactattgc tgacatgtac
    29281 atatcgagga agttcgggaa gttttttcag cacttctata aagcgttctt tttgcagatt
    29341 ccaatatgta tcatctgcct gatctgctgt agaaaaatgg gtaaataaac cttcccattc
    29401 taatacacga ctttctttga tgaatgcagc tgcctctttt acttcttcag gtgtacaaaa
    29461 tccgatacga cccatcccag tgtctgcttt tagatgaatc gaaagaggcg tctctagctt
    29521 acttttctct aaaacagcag ctgctgcttg caaccattcc cgtgtacctg cagttactga
    29581 taaatcatga gcaacagcta cagtcagtgc gtcgtaagga accatattca agataaggat
    29641 gggctgagta aatccagctt ctctcaactc gactccttca tctaaatttg aaacacaaaa
    29701 gcccgaagct ccacctgcaa ctgctgcctc agctgtttca atagctccat gaccgtatcc
    29761 gttcgctttt actactgcaa acaattcttt tccttgcgga agtcttgcaa cttcatttgc
    29821 tacattttca gttatagctt ttttatgtat cactgctttc gttgggcggt gccaagcgac
    29881 aaccatcgtt tttccttctt tctagtcttc caaaataatt tgtgcaaaag ctgtttcatt
    29941 tgtatgagta atactgaccc atacattgcc ttcatgaggt gaacgcgtca caacaggctg
    30001 accattttca ttttttaaaa tctcgacatc ttgaaaggta acttttccga tcccagttcc
    30061 ccaagcttta gagaaagcct ctttgcaagc gtaacgcccg cctaaaaatt ctacttggcg
    30121 atgaaaaggc aaggactgga atagtttcat ttcatcagag gtcaagattc gtgcaatgaa
    30181 ttttggtttt tcttcgatca gccgagtgat cctaggaagt tcgactgcat cgatcccaat
    30241 tccttttatc atatgctttt ctcttttcaa taaatttaga acactctcat tctaccaaat
    30301 tataaccatt ttgccacaaa taagtccaca aataacaaaa atgaaagttt ctcttaaaaa
    30361 agagaaactt tcattttatg tttaatcgtt atttgaacgg attacaaatc cgcgtttttt
    30421 atcattgtga cgtttaccgc catctttttg gctgttatta tttttgctat aaccgccttt
    30481 tgatttgttt ccacgataat taccgccgtc acgacgatta cggttgtttc cgccaccacg
    30541 tttgccattt ttattgtatc cttttttctg cattggcaat gggcgttctg gtgtgatctt
    30601 cactggcact gcatcagctg gatcttttgc tgtcgttttt agcaaaagtg caactaaatc
    30661 ttgtgcagaa tattcttcta ataatttatc tgctgtttgc aggtatttat ctagaccatt
    30721 ttctgcaagt tttgtttcga tttgttcaac tgcagcacct aattgacctt tgaatgcttc
    30781 tttttcggtt ggtggacgta aagtcgtcat ccgttttttc gtcaagtttt caatcacatg
    30841 caagtagtcc atttcatttg gtgtaacgaa agtcacagac ataccgcctt ttccggcacg
    30901 gcctgtacgt ccgatacggt gaacgtagct ttctggatct tgagggatat catagttgta
    30961 cacatgagtg acacctgaaa tatctaatcc acgtgcagca acgtctgtcg ctacaaggat
    31021 atctaaatga ccgctcttaa atgaacgcaa tacgctcatt cgtttttgtt gagacaaatc
    31081 gccatggatt ccttctgcac ggtaaccgcg tgcttctaat ccgcgtgcca attcgtctac
    31141 acggcgtttt gtacgtccga agacgattgt taattcaggt gtttgaacat caaacaagcg
    31201 agtcatgata tcgaattttt cgtattcttt tgcgcggaca tagtattgat cgatcaagtc
    31261 agctgtcatt tctttcgctt tgatcttcac atgatgtgga tttttcatga atttaacgcc
    31321 aatattcttg atagctggcg gcatcgttgc tgagaaaagt aatgtttgtc tttgatcagg
    31381 aacttgtgaa atgatttttt cgatatcttc caagaagccc atattcaaca tttcatctgc
    31441 ttcatccaaa actaatgttt gaacggttcc aagtttcaat gtgtggcggt taatgtggtc
    31501 aagcatacgt cctggtgtac ccacaacgat atgtggacga tctttcaagc cacggatctg
    31561 acggccaata tctgctccgc cgtaaacggc ttgtacacgt acttttttgt cgcgccctaa
    31621 acgatataat tcttcttgtg tttggatagc taattcacgt gttggtgcga taactaaacc
    31681 ttgtaattcg tgacgatctg gatcgatttt ttctaacatt ggtaatccaa atgcagctgt
    31741 tttccctgta cctgtctgtg cttgtccaat aacgtctttt ccagctaatg ctagtggaat
    31801 cgtttctgct tggataggcg ttgcttcttc aaaaccagcg cgttcgactg atttcaacaa
    31861 ttctggtgat aattctagtt ctttaaattt caaatgaatc ctcctatatg gttgttaact
    31921 gaggatgtag cttttttgct accccgtcga tttgttcggt caaagtgtat tgtttctttt
    31981 tgacagtggc cacgcacgtt tttatccatt cttagcccct gtggcaccac cgaaaaatca
    32041 ctttgcgaag tttaggcatt agaaaagcca aacgggtcgc gttcagcttt atcattatta
    32101 tgacatctgg cttcaacaag ttgtttctat ggcaaaacca gtccaatttc tcttcatctt
    32161 tcggcaatag gttattctaa catagttttt cgttttctgc aagtttacag atttttattt
    32221 catttgctga agttgttcta ccacttcaaa taagcccatg ctgttgctgc cttttagcat
    32281 aatactatct gttgctgcaa gattttgttt gatagcatca atcaatttat tcttttcttt
    32341 ttcaaaatag aacacaggta gttgggggta tttttggttc aattcttctt ttagtgcatg
    32401 catttgttcc ccataaagga aaatcatggc gaatttctca ggatcgatat gttcactcat
    32461 ttgcgcatgc atatttaaag actctttccc taattccagc atatctgcta acacagcgat
    32521 tctgcgtcct tttgttggca gatttttaaa agtatctaat accagtccca tggctgttgg
    32581 atttgcattg tagacatcgc tcaaaatagc tgcaccattt cctgccgtta gccattcggt
    32641 tctgttttga gtgatagaaa catgggcgag cccttggcgt atctcaggta tggacagtcc
    32701 aaagaagcgc ccgatcgtat acgcaatcaa agcattcgtt acattataac ttccaggcag
    32761 cgggatcgta aatgtttctc cttctactac aaaatcggtt tgtgcttttc cttttgctgt
    32821 cacttccgca tgaacatcgc catttccaat accgaatgtt gtgactgttt gtactaatgt
    32881 tgccgttaaa ggtgtcagca acggttcatc tgcgggcaca acgagtaatc cgtctgatac
    32941 aagtccgtca gtgatttcca ttttggcttt agcgattcct tctcgcgacc caagattttc
    33001 tatgtgtgct tcaccgatca ttgtgattgc tgcagctttt ggttgagcca taagtgaaag
    33061 ttccgtgatt tcattggcgt gatccatgcc catttccaaa acgatctttt ctgtatcttg
    33121 gggcatgtgc aaaatcgtgt aaggaagacc aatattattg ttgtaatttc cttgcgtctt
    33181 atatgttttg tatttttcag acaagacaga cgcggttaga tctttcgtgg tggttttacc
    33241 attgcttcct gtaattgcaa cgacttctgc gcctactttt tccaagtaat aggttgccaa
    33301 ttgctgcatg gctttcaaag gatctgctac aggaataact ggaaaatttt ttggagcttg
    33361 ttcaacaggc aagctccaaa atgaagcaga tgctccgttt gtgatcgctt gctggataaa
    33421 ttcatgtcca tctcgcgtac cagcaagagg aacgaataaa cttccttcgg ttatcttccg
    33481 gctgtcaaat tcgacattgg taatctttgt cagtgcagag cattcgctgc ccacggcttg
    33541 tgcaatttct tgtattgtta gattcattga gatctctcct aaaaaaggtt gtgaaaaaag
    33601 cgtttggcct aaacggcggg ttcgcatgac tctcacttcc aagtaaattt ctctattcgt
    33661 atttagaagc tagaatgaac gcggttacgc aatcactcca gcctcttctt tatttctctt
    33721 tattcatttt tttcaaaaaa agattgacgc tgatggtatc gattcattcc taactggatc
    33781 agttcttcaa tcaaatcacc gtatttcaag cccatatttt cccataagag tgggtacata
    33841 ctgaactccg taaatcctgg catagagttt aattcattca ggaataattc atttttattt
    33901 gtcaaaaaga aatcgcaccg gctcaatccg cttccaccta acatcgtgta agctaacttc
    33961 gcgtactctt gcgctttttg ataaacttct tctggcactt cggctggaat ctgcatttcg
    34021 attttattat tgatatattt tgcttcataa tcatagaatg ctacgtcttt tacgacttca
    34081 ccaggcaaag tcgtccgaac gtcttcattt cctaatacag caacttcgat ttcgcgcgct
    34141 tcaattcctt gttcaacgat tgctcgagaa tcatactgat aggctgttgc taaagcattt
    34201 tgcagctctt ctcggttttc tgcttttgta atgccgacac tagaacccat attcgccggt
    34261 ttgacaaaca tcggataaag caaagaacct tcacattgat caaatacttt tttaggattt
    34321 tctttccatt gattcttaag tactggtaca taaggaactt gcggcacacc agcagcttgt
    34381 aaaatatact tggtcatgat tttatccatg gcacatgcac tggtcaatac gcctgcgccg
    34441 acataaggca tattcaatgt ctctaagaag ccttggatcg ttccatcttc cccgtttggc
    34501 ccatgtaaaa ctggaaaaac gatggctcct tcttctttga tttcgcccgg attgatcact
    34561 tttcctgtaa agccttcctc tgtctgtcca cttgggtccc atgaaagatg caagacatct
    34621 ttgctggcag gtttttctgt tagtaatgga cctttgaccc attgtccttc ttttgtaata
    34681 aatacgagtt gaacttggta ataattataa taaatggcat ttaaaactga aaatgcggaa
    34741 agaatggaca cttcatgctc tgcgctgcgt ccgccatata gtaaagtaat cttcaaaaga
    34801 ttgtcctcct gtattctaaa tcgttcagtg atttactctc atattttagc acaaaacaaa
    34861 aataaacgaa taacttattt ataaaaaaac gagccagctt ctaaaagaac gagcgtcatt
    34921 tattttttgt cagctagatt atttgtcccg ttttttataa aaagttatga taaagaaaag
    34981 gagggatgat gatggcgcaa acaaatccac gcagccgctt ggcagaaatc attcgagtgt
    35041 tcatcaatta caatgtagtg ccaaactttg tacagcaaaa aaatcccgaa caggtaaaaa
    35101 aagcctttga agaactaggc cccaccttca tcaagatagg acagatgctt tctgttcgag
    35161 aagatttgct ttcttctgcc ttcactcaaa cattcaaaac attacaagat agtgtaccta
    35221 gcgacacatt ttcaacggtc aaaaagacga tcgaaacaga actttctctt tcattatcag
    35281 atatattcga tgatttttca aaatcgcctt ttgcctctgc ttctatgggg caggctcatc
    35341 gtgccaagct gaagaacggt gacgcggtag tcgttaagat ccaacaccct aacatcgccg
    35401 aagagatccg acttgatctt caactatttg aacgagcgat ccctttgatc aaatacattc
    35461 ctgaaactag cgtagttgat ctaaaagggg tactccaaga agtaaaacgt tccttgatca
    35521 atgaaatgga cttcttaaaa gaaagtcaaa atggcgaaca attctatcaa aagaacaatg
    35581 gctggaaaga gatccgcagc cccaagattt atgacgcttt ttgttcgaaa aaagtgatcg
    35641 tgatggaaga aatgtctggt aaaaacttga atcatttaat gaacgccgaa aacaaaactg
    35701 aaacttttat cactggaatt caaaacaagc agctgaaaca agaagttgca aagcttttag
    35761 ttgagaactt tatgaaacag gtgtttgatg atggtttttt ccatgctgat cctcatccag
    35821 ggaatctgct attccatgta ctaacaaaag aagaacagac acaagctagc cgaaaaactg
    35881 aaacagtcca tgaaaaagag ttcggttcct ttgcttttcg agcctccact tctgcagaag
    35941 accctgttgc gccatatacc atcaactaca tcgattttgg tatgatgggg catctttctg
    36001 caggacttag gcaaaaactc acacaagccg ttttagcgct gtatacgaaa gatgcttatc
    36061 gaatcgaaaa agcggtcctt cgactttgtc agcaagaagg ctcgtttgat gaaagtcggt
    36121 tccaccaaga actgacaagt tttcttgaac agtattatga ttctcctatt gatgaaatca
    36181 acttgcaaga agtattcaca catgtcgtga cgatttgtca tcaaaataat ctgcagttcg
    36241 atcgtgatat cacgcttttg ctgaaagcat ttgggacatt agaaggggtg atccgcgtcc
    36301 tcgatcctga agtttccctc atggaagtcg cttcgccttt tgctcaacat tattttctca
    36361 ctcatctgga tgtagaagat acattgaaac aaagcggatt agacttattg gaagggatga
    36421 aggctgcgcc taagatccct caacagctcc accatctatt agaaatgtgg acttcgggac
    36481 aaggaaaagt caatttggaa ttgaaaaagc aagacaaatt attgagcagg atcgaaagta
    36541 tgatcaatcg gcttgttttc ggtatgattt tagctgcatt gatcgtaggg tcctccctgc
    36601 ttgtccaagc agcacctgta gaaaacgcag aggtcgtttc cttattaggg atatttacgt
    36661 atgctattgc cgcattcgtc attatttttt tggcaatcga tgcattgatc caaatgtata
    36721 agaagaggaa aaagtagaaa aaggttgtga cagaaagaat cagcttcaag aaataagaag
    36781 gggttttaca taaattgttt ctcaaatttt tgtgaaaatt cggcttattt ttcgaagagg
    36841 ctacttctga aacaccgaga ataaaaaatg tgaaaaagct gttctgcacc cagtaataag
    36901 aacaatcaaa aagggaacat ggaacacatt tatcctgttt ccctgttccc tttttgatgt
    36961 attcgagcat aaataaaata ccttcgttac ctactatctt ctgtacttgg taaaccttag
    37021 tcaattgcct tttttaacgc ttgacgaaaa gacatatgat ctttctccgt aaagggtttt
    37081 ggaccctttg tccttatgcc agcttttctt aactttccac tatgataacg ttgttctaga
    37141 agcgtgccga tattcgcttc gtcaaattct tttccagagt gatggaacac tcgcacaccc
    37201 ttcggcaata caagtgaagc taaaccataa tcttgcgtga tcaaaaagtc attcttctta
    37261 accataccga cgattttata atccgcacta tcagctccgc ggtctacgta gacgatttgg
    37321 acatgattag cgtattcttt ggtcgtataa tggtccacac tggtcacgat aaccacgtca
    37381 agaccatagg attctcctaa ttttatgaca tcttctttta ctggagaacc atctccatca
    37441 atgaatagcc tcattctttt tcgccttctt ccataaatga taaacagtta ctaatccgct
    37501 cagtaaaaga ccaacattga tccattttgc caagataagc agttgtacac tttctatcgg
    37561 cactgattca tggttcagcg tgatcaataa tagatggatt ggctctccca tttcttttgc
    37621 taaaacaaac aaaagcgtca tcaataaaaa ctggtggatc acactccctt tattttgagt
    37681 agtatacttg acaacgatcc ggcgatccat tggaatagct gtatcagttt gataatattc
    37741 cttatttagc cagctgcctg ttactacgtg ccagaaacta agcagaaaga cacctatcgc
    37801 aaaaccattt ggaatcaaga ggaccaataa agaagaactc agtccaagca attgcatagc
    37861 caatggagac catgttaaac gtttcaaaat ccatggtccg actatttttg ctgcaatcaa
    37921 gcctgctgca taaggcaaat acataaaaat cgaaagtttt tctaatccgt acagtatgcc
    37981 aacataaaaa ctgctaaata aaaaaaggaa attccctagc attccattta gaaaagtaaa
    38041 cagatttagc cagcttggca acttccattc cttcttctgg tgtcctaaaa caaacacgaa
    38101 caagatgaac agcagcaaga aaccataaat agcaagatca aaaagccttt catcgaataa
    38161 caatcgggca tttctcaaaa gaaacaataa gccaaagaat atcaaaaata aaacaagctc
    38221 tcgcgtagct accagatttc ttttgatgtc tttgaaatcc agttcgtaac gcggataatg
    38281 actaaccgta tggtaggcca tgacgtaaaa aagtgtataa atagtaaagc ttgctgcaat
    38341 ctgagtcggt gcaggcaact caatcgcttg atacaggaga aatagccaga tagctgcaaa
    38401 taagtacttt ttcccatcca tattgataaa accttgcgtc ttttcgtgaa aattgaccgt
    38461 ggtattagca ggtacaagcc atgctgcact cagccctagc aaaacacttg aaaaataaaa
    38521 taaaggaaaa taaaatacgc ctaatattcc aagcaatgaa ccagcaccac caatcagcag
    38581 agcgatcatc agcaacgtgt aactatctag accaaatcgt agactgttga ctaaaaatag
    38641 tccagtcatc cgaaaggcat aaaacagcgt aaatggcaaa atcgtcagcc aattatgcga
    38701 gtctgttagt cccaaaaata aaagataagg aataaaaata accgtgttac ttaagataaa
    38761 gggcgttgtt tgtgtaaaat tacgcccaaa tcgtttgagt ttttcgaaca tgacaatggc
    38821 tccttaaaca gtcttataac taatctgctc ttcgatttta gcattaaagg ggaaataaac
    38881 caattttaca gaatatattc ttgtaaaaaa aaatacagaa agaagcataa gcttctttct
    38941 gcatttttac ggtacttgat tactcaagca gacaagccct tctccacaaa agtcttgccc
    39001 gacacccctg catccggcag gtgataaaga tagaaatcaa ttatcctgtg cctccaaaat
    39061 caattaggag ctctgtaaac cagagtcctt ctcgacccgt cgcataaatt tactttaaca
    39121 cagttcctat gtttatgcga gagctttttt cattttataa tcgaccattt gaaatccttg
    39181 accgatatct gaaataagtt cttctgtaat ctcaaatcct tcatgcttat aaacctcgat
    39241 tgcttgatga ttcccctgat tcactcgcaa aaagatctct ctttcctttg tttgcgcagc
    39301 aagttcttca taccagcgaa aaactgaaga agtcaatcct tgaccacgta ctttatttag
    39361 caaatataat ttacttaaat aaatttttcc atttatctct tcataagcag tgtaaccgac
    39421 agtcttttct tcgcttttta ataaaaagta ggacacacct tctgtcagtt ctttttgaat
    39481 ctgttttttt gactgataag ttttcagcat gtaatccact tgtttttgac caatgatcgg
    39541 cacaaaagct tccggccata cttcttgtat gactgccatc agctcatcca gttcattttc
    39601 tgttactttt attttttcca tacacccacg tcctttttta cattataaat gaccttgcgc
    39661 ttgatggaat aaaaagagca tgatcatgct atacacaccc accgaccatg gtttcaagaa
    39721 aatcacaatc tgcataaatt ccctaaaaga taatttcgtc aaaccagcta ctagacagat
    39781 caagtcgtct ggcgcaaagg gaagcagcaa ggtaacaact agtacttttt taatatcttt
    39841 cgtttttctt gtcagcaatt catcaaattt ctgatacttt tttggcgata aaataagctg
    39901 gacaaaggct acgccatagt aacggacaag caaaaatccg attgcttccc caatcactag
    39961 gccaatacaa ctatataaaa gcccaaatcc attgccaaac atcagcatgc ccgctactga
    40021 ggagatccct cccggcaaaa taggaatgat cacttggatc acttgcaaca gaacaaatat
    40081 catcactgca tacttgccaa attgctggat aaacgcttgc aaagacgtgc tcgatcgaaa
    40141 aatcccatga tgataagcat aaagaatcaa cacaaagaaa aaaaacagac caataatggg
    40201 catgatctga agacattttt gtaaaactga tcctttttta gacatctata ttccccacat
    40261 cttttttcat ttattaaaac tgcctc
//
LOCUS       DAXQKX010000021        38062 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.021, whole genome shotgun sequence.
ACCESSION   DAXQKX010000021 DAXQKX010000000
VERSION     DAXQKX010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 38062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38062
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.021"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            131..463
                     /gene="traE"
                     /locus_tag="ACF3MF_001218"
     CDS             131..463
                     /gene="traE"
                     /locus_tag="ACF3MF_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraE"
                     /protein_id="HFE3927225.1"
                     /translation="MSYTGILSLEDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
     gene            1054..1383
                     /locus_tag="ACF3MF_001219"
     CDS             1054..1383
                     /locus_tag="ACF3MF_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927226.1"
                     /translation="MIQKFAKMSKTAWIEKLENDLSVMRLAPKKFKREIAEKEAILSV
                     LNAVDDKCPVKISFSDIATIIEGIYYGEVDEEISSTKDLLDFLDKNKDTFIVLTDYEE
                     VTTNEKL"
     gene            1370..1711
                     /locus_tag="ACF3MF_001220"
     CDS             1370..1711
                     /locus_tag="ACF3MF_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
                     /protein_id="HFE3927227.1"
                     /translation="MKNYDPNSRWGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQKLTDNPIGFGLLPEDDQGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSV
                     EIIEFVADKEE"
     gene            1825..2064
                     /locus_tag="ACF3MF_001221"
     CDS             1825..2064
                     /locus_tag="ACF3MF_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927228.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKEVFKSLSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            2131..2370
                     /locus_tag="ACF3MF_001222"
     CDS             2131..2370
                     /locus_tag="ACF3MF_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927229.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKTMKQKHLKRLSVMQYINDMQIT
                     GKEKACLLGSMKNFEQLRRTYVKKSSNCQLLLEVS"
     gene            2456..3127
                     /locus_tag="ACF3MF_001223"
     CDS             2456..3127
                     /locus_tag="ACF3MF_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HFE3927230.1"
                     /translation="MRKWLFGFLGVALIVFCSVFGYVSYQKHEGKVFKQNIEKKMPVD
                     QINEHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQAFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            3180..5156
                     /locus_tag="ACF3MF_001224"
     CDS             3180..5156
                     /locus_tag="ACF3MF_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFE3927231.1"
                     /translation="MAINRYVKKAGMLVGMLGIIASCFQGYQVHAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PREDSDLTNAKVDEIVQDVEDKGSNSEYVKNATNKITSAVDENGEITFTDQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDKTGSGFLKNIHLYPKNIVSKLSFELTK
                     FGDDGAAQSKQTLLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGTDGITVNGVKSETSPYSVFKWGDTA
                     GQGLSYVAAKANIKVTNKDGSVVLKENTDYKIQNSENGFVIDFIVNNGQVSDTVASLH
                     GQDLQMTYNMYVNDSAAVANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLVDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGEYSLEETKAPTGYQKLTEDIAFKVNKNSFKEENRITVKNNQKAAI
                     PLTGSNGFQTYVLISCLLLGAGALSAVVYFKKKA"
     gene            5169..5906
                     /locus_tag="ACF3MF_001225"
     CDS             5169..5906
                     /locus_tag="ACF3MF_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFE3927232.1"
                     /translation="MIIRKPPKRRVMHKLMIFFWLLSAVAVYLIPAVETNVAKFQQQQ
                     RILAIENLEKTDSSLDVAKIELGDPVGVLTIPSIPLKLPIYDGTSDKILENGVGITEG
                     TGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGQKFFIKVNEEQHAYQIYRIEEVK
                     AEELQKNYLDYLMPEKDQDRITLMTCTPKGVNSHRFLVYGERVSFSKEDLKLQKKAKN
                     RKSISLDWRLALLFAFFAFLLFLFIKK"
     gene            5920..6747
                     /locus_tag="ACF3MF_001226"
     CDS             5920..6747
                     /locus_tag="ACF3MF_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
                     /protein_id="HFE3927233.1"
                     /translation="MNKRKWLFVCVAALFATAAYSQISFADSSTTPTTSQTTDSSTTA
                     TSDTDSSKNTAEETADSSTSSTESAESTSESSSETSEKLQEVEDTQVIKQNIHIQKII
                     SSNRINNQGRQVTQQEGVNGAKFIVYDITNILEEMTQDDNEKNQSVEIIESKLKDRAK
                     KLSYDQLKKVTEGETQTIDDQEGVIDFSIEVPANKKQAYYIVNESSPENISNSEDIVL
                     LTPVSDEKGEFLTDVWLYPKSKKSEPKEEIKKVVSTGVKKNFFDNCWDFFTHLFFND"
     gene            6757..7005
                     /locus_tag="ACF3MF_001227"
     CDS             6757..7005
                     /locus_tag="ACF3MF_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927234.1"
                     /translation="MKIIKMLVFNLSFLAATILCCGLVFSQLSIYPRYQRLFVHFLNI
                     QHASMPLEVINKLLINPIFMASLFLLAGLVTWVLGKKE"
     gene            7048..9147
                     /locus_tag="ACF3MF_001228"
     CDS             7048..9147
                     /locus_tag="ACF3MF_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HFE3927235.1"
                     /translation="MENKIHCTTGRVFTLVLFLFLLLFARGTAVQALEKVDPSQIKEN
                     NNLVLYHDSDSLRNIEVTGINGFKILDEYSTKKQKVLAWPKVKDLKSTSKIVAHYQKV
                     GTYLGKEIDCDVTFSNFVAHAGVNQDGLAKTINGKKYYNYLLFDKNIYRGFFMQSINV
                     MNVKLDFKYAGSKTKVALSEPQPEINSKMRSMRAAGIELNDTFLSIYSLNGQYQQRVS
                     WYNDNNESVGERNIDMREFVGYEKMDRLPYFVTTDTACAEYKAPALSTNNLTSKVVGG
                     RAEKAYSSNDHFTDVVGADTYHRSGVTYTLQGASPTFMIGANTNSMMFSFDTALLWTP
                     QPSKPTKEVFNKANTEEAAHNIDKKVIPQGSDVYYHIHQKFDALTVNTMNKYKSFKIT
                     DTFDSKNFDMVSDGKNYDGALWYVEANGTWKKADTGGKLTVSGNTVTYTASDSFLANA
                     ANYGRDYILQLHMRAKNDAKGIAPNVATVTFNNDPNKGTQKTNKVENYFSLKPNKKVE
                     QDGKDVDGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDIALDHYKQFSIQDPVEA
                     RLTYKEGSARVIDMSTGKDITSEGILTYDSHSRTLKWEASADFLNNNLLDGREIQLIF
                     TAKTPLNEELDIDNQAKVSVESIEKATNVVTIGVKPNLPQVIVPKTGSNHLVLTVIGS
                     ILFLTLASLGYVVLKLK"
     gene            complement(9185..11242)
                     /locus_tag="ACF3MF_001229"
     CDS             complement(9185..11242)
                     /locus_tag="ACF3MF_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HFE3927236.1"
                     /translation="MKLFNPKTVLAIGTFAASLSLAGSVDAASTNVMYRLYNPNNNEH
                     FYTSSKKERDHLVKIKWGNYEGPAWEAPTSGGHLVYRLYNKGLRDHHYTASWDEVKWL
                     TKNYGWTYEGPAWRSAEKNNKPIYRLFLPGVKSGSHHYTASWKEVQWLTKDYGWKYEG
                     IGWYGADTSKPKVNKSALEALYTSVKGTKKGDYTDNTWNAFQTALNNAKKVLNDSKAT
                     QKQVDSAKNKLDSAYKGLKKKPVPTVNKAELQALYNRVKSTAKGDFTEESWNNFQTAL
                     SNAKKVLDDSKVSQTQVNNAKNSLDAAFKGLQHKPETPKEYMVTINHIDNQTGQVIAT
                     DQAKVTSGSTYTAKAKAFKYSEGAKDNFSYKVIGNDTQSKTITGNTTITFNYNQVHQI
                     NLLCNNNYKNEGRVDILKEQIINVTHGESVTLTAPSIQGYVLDDRVEPTNSVTLNNVT
                     ESQNYIFNYTRKFNVTVNHVNADTNAVLSSESKTVYEGDSFSTPWKNMTDQNYFLCRN
                     DDPTVTVDKNGQRSINNVDQNKTITFKYKKISLDELRNFMRQKELAWLNDYRQQNGVA
                     PMQFNDIVQQAADIRAKELQVSFSHYRPGGGTFQDLLESLGCYGAKGENISQTGLYID
                     DLLSDDGAIDAMVGWKNSPAHNANLLYNNQSILGLGHNFVVDSAGRIGVDNVFISANP
                     IFK"
     gene            complement(11356..11568)
                     /locus_tag="ACF3MF_001230"
     CDS             complement(11356..11568)
                     /locus_tag="ACF3MF_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927237.1"
                     /translation="MYADKKKIEWLLFDSGKSVRSISIESGVPLTTVSDLANKRSSID
                     NMRFINAMKLNKLAEEIVDINTSTNK"
     gene            11755..12222
                     /locus_tag="ACF3MF_001231"
     CDS             11755..12222
                     /locus_tag="ACF3MF_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927238.1"
                     /translation="MKKKQLWFVSMFAIFFIILSGCSSNKKSEAKEDNSLLQPGTVWK
                     EEVGGLIHNLKIIDDTTWEYSESVWHPDPVQITVKRQKDYEGLERYKIVDSAGIREFI
                     NKPDSLFIVVPYEKDGVKKIIFLGSSKDEKRTKEKLIHDGSQSNKYKLQKTSE"
     gene            12219..12461
                     /locus_tag="ACF3MF_001232"
     CDS             12219..12461
                     /locus_tag="ACF3MF_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HFE3927239.1"
                     /translation="MIASLFICPEGGITVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            12479..12781
                     /locus_tag="ACF3MF_001233"
     CDS             12479..12781
                     /locus_tag="ACF3MF_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927240.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAVAA
                     VASIALGGIFFFFGRRGAENGKTHVGYVLLGVGVILAAASIVVSMFSMFGQTPQGL"
     gene            12852..14906
                     /locus_tag="ACF3MF_001234"
     CDS             12852..14906
                     /locus_tag="ACF3MF_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927241.1"
                     /translation="MFFTISGNAKLDKELIRKATKKVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGQVLEQENQSSVKLTLTLHDKEGKIEKAGTEYVFGSLDYQISEGFYPTLIDLIR
                     LDIFKDTDETMSVEESYRNEKILQVLEEELESDQRKVNQVSEVEANEEVPWERPIFPK
                     DESKEKEKGIIDEQADILTHKSIFEEENEVMGQLEVDPFEETMEDEETAEVEVDPVEA
                     NEDPTWTEGDSQEYIEPLISEEVEKNETEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKAKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCVE
                     KINNFTQTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLRISKELNEQLNKLYQTT
                     TEVLMEKHEQIQQELQAQIPKWKKEYEIHQQELKEQEEKQRKKEKEREQLELKKREQD
                     LAEQKMAIEKQRLEQEKEKEAAARKERQEQMDTLRQAQLNYLTHPQPVAAVQTPVNNQ
                     ANLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTASIKEEAQE
                     QARKEYEQQLEELLNRTNQSTTESSMENSKESDSSKAKEGSSDSTVQSNTSESSESNE
                     VK"
     gene            14906..16738
                     /locus_tag="ACF3MF_001235"
     CDS             14906..16738
                     /locus_tag="ACF3MF_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HFE3927242.1"
                     /translation="MRVRETTKRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     KKIFYSGLVYLPLEYLVTRVPEVFNRLEIVKGSLQGINLFQLQEMPQVFHFDSAGFWN
                     PFTPTTSLGTRLAISTVCVVPAVLMGLKMDMWFRPLADGQKGDNRLMTLKEIQQIYPQ
                     IPETKTTFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     KQSSMVVNDPKTELYVGSKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPDNEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSVGFPKYLDLKLHESLLNQRVVVEFYHKGK
                     KFHEERVKVGYKGFSEINFDCHLVAGDQVCLKYDHQGKEYVAWYEFSQRVLKDEEGNI
                     VYRKKRGETHLPELEKEAVLTLDEEKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNSVTCLA"
     gene            17451..19349
                     /gene="ltrA"
                     /locus_tag="ACF3MF_001236"
     CDS             17451..19349
                     /gene="ltrA"
                     /locus_tag="ACF3MF_001236"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFE3927243.1"
                     /translation="MTNTKGISLKNKQLRHAEYYDMTETFDELHAMSVAKSNFKNLMK
                     FIIDDNNIFLAYRNIKKNKGSATAGYDGVTIKDIEKLACGDFLTIIKRRFKDYRPRKV
                     KRVEIPKPNGKLRPLGIPSIWDRIVQQCILQILEPICEAKFNKHSYGFRPNCSTENAI
                     ADCLARINQSKMNYVVDIDIKGFFDEVNHTKLMRQIWTMGIRDKQLLVIIRKMLKAPI
                     VMRNGNVVFPTKGTPQGGILSPLLANICLNEFDWWIANQWEERTVKELKHHYRKNGAW
                     DKGNIYSKLRSHTSLKEMYLVRYADDFKIFCRTGEEAQRAFYATQKWLRERLKLPISM
                     EKSKVTNLNKAESEFLGFSIRLHKKGKKKVAFTYVCRKAEENIKNKLKQQIKKIQYAG
                     AKKNRHRAIGDYNMMVIGIHNYYRIASHCSVNFTEIYRSVRTVIEARLKARGMTKNGI
                     YGQDHEGYRPYLKSKQMRYIEGFPILPIGYIKKRTPLNKRRNLNKYTKEGRKLIHQEQ
                     QAIESWKIKYLVKGFSNNKKYTVEFSDNKISKFISQKGKCAITGNELLMEEIECHHIN
                     PYHLSKDDSYKNLVIISREIHRLIHATSEETILKLLRLLKLNHYQIRKLNTYRKKAAN
                     FPISIKMN"
     gene            19466..20266
                     /locus_tag="ACF3MF_001237"
                     /pseudo
     CDS             19466..20266
                     /locus_tag="ACF3MF_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
     gene            20263..22794
                     /locus_tag="ACF3MF_001238"
     CDS             20263..22794
                     /locus_tag="ACF3MF_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
                     /protein_id="HFE3927244.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDANPKTVTKVLQDYGNYLQYQDV
                     FSWICNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNELFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKSFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PKQAKEMADKDKSGLSDLQKDRLRALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYR
                     RYISSPGIILAGESSLAVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSA
                     IEDISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQ
                     SVTKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGF
                     GHRKDVTPDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGT
                     AEDLTEKAKDTLEDKLDGTRAKELAEAVKNPSEALEKQKEKASEVKEGLKDAYGEGQV
                     NAAVKANTTTEKENQEGIVIPSVKDHQEALHSNENSIEEKNSIEERNSEEGKNGQLPK
                     TDPEQYRYKPNSDLENEKRISDLSKVNQEDKAENEGQLPKTDPEQYRYRSVNSENEKR
                     ISDLPKRNQEVQTDEDSIVLPNDNGIEVGTEKSTKIGLPKAQNLPMKDSRLNQFKDND
                     QSFVHQSPAGTVQMKPSRLPENGNLTTVSYNLSESGETGNASVQNVVTREAAPKPIQN
                     VHTGYKPANVAFTAPTKINVTRETKNRNNALKEQLLRDIKQDIKP"
     gene            22844..23176
                     /locus_tag="ACF3MF_001239"
     CDS             22844..23176
                     /locus_tag="ACF3MF_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927245.1"
                     /translation="MDKYINMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKMVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFADKNHYHALDPNRNY
                     HGTYKEDE"
     gene            23177..23770
                     /locus_tag="ACF3MF_001240"
     CDS             23177..23770
                     /locus_tag="ACF3MF_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927246.1"
                     /translation="MRVKGQNSVERKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLRKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            23933..25627
                     /locus_tag="ACF3MF_001241"
     CDS             23933..25627
                     /locus_tag="ACF3MF_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HFE3927247.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKCFLAMIDECHNGATCSAVKSCGLQVV"
     gene            26315..28192
                     /gene="ltrA"
                     /locus_tag="ACF3MF_001242"
     CDS             26315..28192
                     /gene="ltrA"
                     /locus_tag="ACF3MF_001242"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFE3927248.1"
                     /translation="MTKETSPKDRKLRHAEYYGMTEIFDKIYSKSLKGDNFKNLMQII
                     ISDNNIVLAYRNIKRNHGSVTRGEDGVTIKDIENLNRNEFVEIVRKRFAHYNPRKVRR
                     VEIPKYNGKLRPLGIPSIWDRIAQQCILQVLEPICEAKFNNHSYGFRPNRSAEHAIAD
                     CMARMNQSHMEYVVDVDIKGFFDEVNHTKLMRQIWSMGIRDKQLLLIIRKMLRAPVVL
                     PNGKLIYPTKGTPQGGILSPLLANINLNEFDWWIANQWEEKDAKELKHHFRKNGAWDK
                     GNIYHKLRKSTTLKEIYLVRYADDFKIFCRNYNEAKKVFYATKMWLQERLKLPISEEK
                     SKITNLSKEESEFLGFTMKLVTKGNKKVVNTHIGTKAQSMIKVKLKKQIKRIQKSPNS
                     KDTFIYIGVYNSMVIGIHNYFKIATHCSVAMRKIARELRPSFEIRLREQGISKEGQYG
                     KYEGYKPYLRSGQIRYIRGFPILPVGYIQHRHPMCKKRNINKYTEEGREAIHKKQQTV
                     EEWKISWLCSNPVLSKRATIEFADNRISKFIAQKGRCAVTGEELILSEMHCHHIIPYH
                     ESKSDSYENLVIVTEEVHRVIHATQSETIEELLKYLKLNPKQKEKLNELRLKVGNEEI
                     S"
     gene            28323..28700
                     /locus_tag="ACF3MF_001243"
                     /pseudo
     CDS             28323..28700
                     /locus_tag="ACF3MF_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
     gene            28700..29905
                     /locus_tag="ACF3MF_001244"
     CDS             28700..29905
                     /locus_tag="ACF3MF_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFE3927249.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWLFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYK
                     LLPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKF
                     PNSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMS
                     IITSNKLTEYDEFAIKHWGEGGNNNGTITGEWTNPFPGSSLDKSSFSGGQLFGTNPGG
                     EFRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVY
                     QEFANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFTDDGTWIDP
                     LPSLNSSKK"
     gene            29921..30565
                     /locus_tag="ACF3MF_001245"
     CDS             29921..30565
                     /locus_tag="ACF3MF_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927250.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQETNTFKIEEVAK
                     NASEKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPADDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVIDFSYFTR"
     gene            30576..31382
                     /locus_tag="ACF3MF_001246"
     CDS             30576..31382
                     /locus_tag="ACF3MF_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927251.1"
                     /translation="MSKKKGERQRFKKRKSYLQWLGIFMILGFLILASPIYTNQKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIRAKVIKVSDDYFAVKLTHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQLKDQEEIIQKLQEKIDRMTKEKI"
     gene            31404..31634
                     /locus_tag="ACF3MF_001247"
     CDS             31404..31634
                     /locus_tag="ACF3MF_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927252.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYVAAKKYFTADNK"
     gene            32180..32455
                     /locus_tag="ACF3MF_001248"
     CDS             32180..32455
                     /locus_tag="ACF3MF_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927253.1"
                     /translation="MDLLIRNIEEKYINKIDKRCEELTVKTGKKWSRNQYLKVLIEND
                     FDHALLNYKKDQFDRLLEKFVDIQTYNTKTLEEYIATNNQLIGLLIE"
     gene            32497..32919
                     /locus_tag="ACF3MF_001249"
     CDS             32497..32919
                     /locus_tag="ACF3MF_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927254.1"
                     /translation="MAKATRKHVYLYDMHIEVLDEIISTHEDISNYSEAVRHLCMMYD
                     PKIEEKINPIQIKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAEERVE
                     GKIKSNQTKKYSSKLKKPVNESVHTRVDPFDPTKILKR"
     gene            32938..34530
                     /gene="mobP2"
                     /locus_tag="ACF3MF_001250"
     CDS             32938..34530
                     /gene="mobP2"
                     /locus_tag="ACF3MF_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobP2 family relaxase"
                     /protein_id="HFE3927255.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEMERRTPEE
                     EQELQRIKNALEDFYIPEGETFSESKTDKEFSETSNEAQSLMEHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTQREQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVISHDNSYLEKMGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEIENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPEKRSEWNYGDENRTKLSPFTRGKLDELTKYVLTKEPGYQEYIQ
                     ISKALKEEAKSLYGESKRETKNAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVN
                     QMQSIYNERSFRTLKQLPTNEYKYSYQEFVKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            34542..34877
                     /locus_tag="ACF3MF_001251"
     CDS             34542..34877
                     /locus_tag="ACF3MF_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927256.1"
                     /translation="MKQYLDQWKVIEGSLKEERIEQLPDCLEKEHLFQISEMLRNEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEINEEGINNFPCESI
                     EESISLTEC"
     gene            35024..35218
                     /locus_tag="ACF3MF_001252"
     CDS             35024..35218
                     /locus_tag="ACF3MF_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927257.1"
                     /translation="MTQTTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQNGNI
                     LTLNLTTKMFVDAVENYPFV"
     gene            35250..37622
                     /locus_tag="ACF3MF_001253"
     CDS             35250..37622
                     /locus_tag="ACF3MF_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArdC-like ssDNA-binding domain-containing
                     protein"
                     /protein_id="HFE3927258.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNNQFQKLFDHQKLTNGQ
                     PMNDKRNGRSWFNQQEKIENKIQSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIENIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKEKSEKGKENLLPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     TPTDSVKEKETDHFYRVEFNENDPAKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNHPIYLELARLCEQSPEKEQEQTVKNEPISKV
                     QNEIKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DQTGQTELQVGIQAVAKNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     ATWTKNSQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTVETAEQKNIVPVGSLWIDKKDGKVLEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            37683..>38062
                     /locus_tag="ACF3MF_001254"
     CDS             37683..>38062
                     /locus_tag="ACF3MF_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927259.1"
                     /translation="MTEKKMSLIDRCKQMDIVDFARNNGLAVANKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRN"
BASE COUNT        14074 a         5925 c         7794 g        10269 t
ORIGIN      
        1 ttagagggaa cgcatgtttg gatgcgttcc ctcttttttg tttgtcatga acgaaaatca
       61 attctctatt tttgaaaaat aacaagaaaa acttgttaaa aatatttaaa gtaagtgggt
      121 ggattatttt atgtcatata caggaatttt gagtctcgaa gatatttgtc actacggtaa
      181 acggtgtacc gctacagaaa agatcacgaa gaaactatca actggtcaaa gtaaaaccgt
      241 tgtgcagtgt aagaaatata taatccagaa agacaaagtc tcagaagaaa tgatttatta
      301 cattgggaaa caaaaacaaa taattttaaa agatcctatc cctttaaaag agctatatcc
      361 aacaatcaaa catgtttatg accaaaacgg tgtactgatt ggtcgaagaa aaaatggagt
      421 cttgcgttgt accgcaaaag ggatggggcg tttaatcagc tgaattgatc attctcataa
      481 cttgtatttt atcgtttttc gcttgcttga aaatattgtc gagacttcta aaggaactta
      541 gaatcactag aaaaataagg agtagacttg atctatcaac aattcctttc ggggggtgac
      601 ggggtaggtt tttacgattg gtaacgtaaa aaattggtca atcgagtaaa tgcccttgtt
      661 tggatagtgg tgaaatgaat ttgtgtaaat aatatgcaca gagtaaacaa gagggaattt
      721 agaagttaga caagttagaa tagcgcctag attaatcatg agcagctact aagggatcta
      781 ggctttgacg caaactcatg gaataaggag taggtcttct cgtaatgggg aggacgcaca
      841 agaaattgtg tcgtgtgctg cagtacatgt agatacttgc gaagacgttg atctttggat
      901 caatcgagca tttaccgttt tctactaggg tttctcgttt cggacgccat aaacgagtcg
      961 atttatttta tatatttttg agtgaacgaa aaacgataaa aatattcgtt atgaagtaaa
     1021 actaatttag tagatagcaa aggtggtaga ggaatgattc aaaaatttgc gaaaatgagt
     1081 aaaactgcat ggattgaaaa gcttgaaaat gacttgagtg tcatgcgatt agctccaaag
     1141 aaattcaaac gagagattgc agaaaaagaa gcaattttgt cggtattgaa tgcggtagac
     1201 gataaatgtc cagtaaaaat tagtttttca gatatagcaa caattatcga aggtatttat
     1261 tatggtgaag ttgatgaaga gatatcttct acaaaagatt tattagattt tttggataaa
     1321 aacaaagata cctttatagt actaactgat tatgaggagg ttacaacaaa tgaaaaatta
     1381 tgatccgaat agccgatggg gaacacatac gattaaggtt tctttccaac gttgggatta
     1441 caaaggattt gtgacgttta gaagaggcgg aaattgtaaa ggattagatg ttttagcatt
     1501 agacgaggat gatttatacg atcaaaaatt gactgataat ccaattggat tcggcttgct
     1561 acctgaagat gatcaaggta atgaatggtt taaaatgacg cttatgaatg ataatggaga
     1621 cgaattatct gttgaagata cttggtcata tttgagtgat tatattgtca gcgttgaaat
     1681 cattgaattt gtagcggata aagaagaata aaaactggag gaataaattt tacagataaa
     1741 ggcttagaag gagtcacgac gattaataaa aaggtagtat taccttaggc attgagtaag
     1801 gaatttattt aggaggaaaa ttagatggcg cgaccagttt tagaggcgat ggatatggat
     1861 actttgacaa aaggaaggta tgtacagctg ttagctcgtg gttattcacc taaagaagta
     1921 ttcaaatccc tgtctaaagg aacagatatg gaaaaagaaa gattacgaaa agaattcgat
     1981 tattggagaa cccataatgg aatcaaggat ttgaaaccag cacggccagt aattaaacga
     2041 aagaaaaaga taacccaaga ctgaagtgta gagcgtatgt gatcataggc ttttttattt
     2101 ttgcaaaaaa caaggaaggt aggaaaactc atgaattatg aagaaatcga aaacagaaaa
     2161 aaagtgtcga aagaaatgga agaaaagttg ctaaaaacga tgaaacaaaa acaccttaaa
     2221 agattatctg tcatgcaata tatcaatgat atgcagataa caggaaaaga gaaagcttgt
     2281 ttgttaggtt caatgaaaaa ctttgaacag ttgagacgaa cttatgtgaa aaaaagttct
     2341 aattgtcaac tattgttaga agtctcatga cattcattaa tagaattcat ttttaaaact
     2401 ttttctatgg aaatgagaaa aagatttttt gttttgtctg aaagggggta gctggatgag
     2461 aaaatggtta tttggttttt taggagtcgc tttaatcgtc ttttgcagtg tgtttggcta
     2521 tgttagctac caaaaacatg aaggaaaggt gtttaagcaa aatatagaaa aaaagatgcc
     2581 cgtagatcaa atcaatgaac atgcaaagag ttataaggag gatgcaacga acgtcaataa
     2641 tgatatgtct ttggggcaaa tgttgtccat acaaaaagaa gcaatcgaaa tgggtgtcaa
     2701 taaacaagcc tttgcacaaa ttcagatacc tgcacttggt ttagcattgc caatttttaa
     2761 aggggcaaat caatacactt tgagtcttgg agcggctact tatttttatg aagatgccga
     2821 aatgggcaaa ggaaactatg tcctagcagg tcataacatg gaaatgccag gtgttttatt
     2881 ttctgatatt caaaagttgt cattagggga ggtgatggac ttagttagta acgatggcgt
     2941 ctatcgttac aaggtaacgc gtaaatttat cgtacctgag tactttaaat taatcgatgg
     3001 cgttcctgaa gagaactctt tcttgtcttt accaaagaaa ggagagaaac ccttattaac
     3061 gttgtttact tgtgtttata cgtcacaagg aaaagaaaga tacgtggtac agggagagct
     3121 acaataacaa ggttttaatc aacgcgagtc gttgaaatat gaaatgagga gagtaaaaaa
     3181 tggcaataaa tcggtatgta aaaaaagctg gaatgcttgt tggaatgtta ggaatcattg
     3241 caagctgctt tcaggggtat caagtacacg cagaagatgt cacgcaaaaa acaccaccag
     3301 agaaggtcaa tatcacggtt cataaattaa tgtacgatca aggaacgcaa ttgaatgttg
     3361 atattgacgg gatcaaaaac gatggttata cgcacgatca atatcctaca ggtgtaacga
     3421 aatacaacaa ggcagattat ggtgatgttg agtttacgtt aggaaatatt acggatcaag
     3481 tattaccgag agaagattct gatctaacca acgcgaaagt ggacgagatt gtacaagatg
     3541 tagaagacaa gggatctaac agtgagtacg tcaagaatgc aaccaacaaa attacttcag
     3601 ctgtagatga aaatggtgag atcactttta ctgatcaacc agcctatgtc aattccaaag
     3661 ggaatgtata tgtggtttat gaaagtaaat ccgctgctgg attagtcaca caaaaagcaa
     3721 aaccaatggt tgtgattgcg ccaatgacag ataaaacagg atcaggattt ttaaaaaata
     3781 ttcatttgta tcctaagaac attgtttcta agttgagttt tgaattaacg aaatttggtg
     3841 acgatggcgc agcccaaagc aaacaaaccc ttttaaaagg ggcaaaattt gagttataca
     3901 agggcgaacc tggaaaagga acaaaattgg gtgatcttgt atcggatgat caaggaaagc
     3961 tgactgcgac tgatttgact ttaggaaaat actattttgt ggaagttcct tcggaagttg
     4021 tagtgggatc agatcaagaa ccaacagcag atcaatattt attaggcgca gacgctcgca
     4081 acgatgcgca taataaatta acctttgaaa ttaccaatga cggcgtgaca agtgacttaa
     4141 aagcttccta cgtgaactat aaagcaccag tgatcgataa aacagtgaca aatggaacag
     4201 gacaagaaca ttctttccaa attggtgacg cagtgaatta tcaaggaacg attcatatcc
     4261 ctacagatat tgcaggtgga acagatggga ttacagtaaa tggtgtgaag agtgaaactt
     4321 ctccttacag cgtatttaag tggggagata cagcaggaca aggactttct tatgtcgctg
     4381 ctaaagcaaa tatcaaagta acaaataaag atggatctgt ggtattaaaa gaaaatacag
     4441 attataaaat ccaaaattca gaaaatggct ttgtgatcga ttttatcgtg aataatggcc
     4501 aagtaagtga tactgtagca agtttacacg gacaagatct tcaaatgact tataacatgt
     4561 atgtaaatga cagcgcagct gttgccaatc cattaacaaa tagcgtggat ttcgtttata
     4621 acaacaatcc atttaatcag gaagaacacc acgaaaaaac gaaagctgac gttgtgactt
     4681 atggtgcaaa attcttaaaa gtcgatagcg gactatttgg aacaggaatc aaagcaacac
     4741 cgcttgaagg cgcagaattt gctgctaaaa acgcagaagg aaaatattat ggtggattag
     4801 ttgatacgga taaagacggt gtcaaagaag cagtatgggt agacgatgta gcaaatgcag
     4861 cgatcctaaa atcagataaa gaaggtcact ttgaaatcac tggtttaact gaaggtgaat
     4921 attcactgga agaaacaaaa gcaccaactg gttaccaaaa attaacagaa gatattgcat
     4981 ttaaagtaaa caaaaactca tttaaagagg aaaatcgaat cactgttaaa aataatcaaa
     5041 aagcagctat tccattaaca ggtagtaatg gtttccaaac gtatgtattg atctcttgct
     5101 tgttgctagg agcaggggca ctttctgcag ttgtttactt taagaagaaa gcctagaagg
     5161 atcagctaat gattattcgt aagcccccaa aaagaagagt catgcacaaa ctgatgatat
     5221 ttttttggtt gctgtcggca gtagcagtct atttaattcc agctgtggaa acaaatgtag
     5281 cgaaatttca acaacagcaa agaattttag ccattgaaaa tcttgaaaaa acagattctt
     5341 ctttggatgt tgcgaaaata gagttaggcg atcctgttgg tgttcttaca attccaagta
     5401 ttcctttaaa actaccaatt tatgacggaa cttccgacaa aattttagag aatggtgtag
     5461 ggattacgga aggaactggc gatattacag gaggaaacgg taaaaatcct ttaatcgcgg
     5521 ggcacagtgg actttataaa gataatcttt tcgatgattt gccttcagta aaaaaagggc
     5581 aaaaattctt tattaaggta aatgaagaac aacatgccta tcaaatttat cgaattgaag
     5641 aagttaaagc agaagaatta caaaaaaatt atttagatta tctcatgcct gaaaaagacc
     5701 aagataggat cacgttaatg acatgcacgc caaaaggtgt taactcacac cgctttttag
     5761 tgtatggtga acgagtgtca ttcagtaaag aagatttaaa actacagaaa aaagcaaaaa
     5821 ataggaaatc aatttcattg gattggcgat tagcactgct attcgctttt tttgcgttcc
     5881 tattattttt atttataaaa aaataaggag gagatcggaa tgaataagag aaaatggctg
     5941 tttgtttgtg tagcagctct ctttgcaact gcagcttact cacagatatc ttttgctgat
     6001 agcagtacta ctccaactac cagtcagaca acagatagtt caacaactgc aacaagtgac
     6061 acggacagtt cgaagaacac tgcagaagaa acggcagatt caagtacgag ttctactgaa
     6121 tcagcggaat caacgtcaga aagttcttca gagacttcag aaaaactgca agaagtagaa
     6181 gatacgcaag taatcaagca aaacattcat attcaaaaaa ttatttcttc gaatcgaatc
     6241 aacaatcaag gaaggcaagt gactcagcaa gaaggtgtca atggtgcaaa gtttattgtc
     6301 tacgatatca cgaatatctt agaagaaatg acacaagatg ataatgagaa aaatcaatcg
     6361 gtagaaataa ttgagtcaaa attgaaagat cgagcaaaaa aactttcata cgatcagttg
     6421 aaaaaagtga ctgaaggaga aacccaaaca attgatgatc aggaaggcgt gattgatttt
     6481 tcaattgaag tacctgcaaa caaaaaacaa gcatactata tcgtcaatga atcaagccct
     6541 gaaaacattt caaatagcga agatattgtt ttattgacac ctgtttcaga tgaaaagggt
     6601 gaatttttga cggatgtttg gttatatcct aaatcaaaga aatcagagcc gaaagaagaa
     6661 attaaaaaag ttgtatcaac tggtgtaaag aaaaactttt ttgataattg ttgggatttt
     6721 ttcactcatt tattttttaa cgattaggat gaaatgatga aaataataaa aatgttagtt
     6781 tttaatctat cttttttagc cgcaacaata ttgtgttgcg gtttagtttt ttctcaatta
     6841 tcaatttacc caagatatca acgattgttc gttcattttc taaatatcca gcatgcttcc
     6901 atgccactag aagtgattaa caagctctta atcaatccaa tttttatggc tagtttgttt
     6961 cttcttgcag gattggtaac gtgggtatta ggaaaaaaag aatgagaagc ttacaatcgt
     7021 ttaacaaaat aatagatgga gggcattatg gaaaataaaa ttcattgcac tacgggaaga
     7081 gtatttactt tagtgttgtt tttgttcctt cttctttttg caaggggaac tgcagtccag
     7141 gccttagaaa aagttgatcc gagtcaaatc aaagaaaata ataatctggt actttatcat
     7201 gatagtgatt cattgagaaa tatcgaagta actgggatca atggatttaa gatactagat
     7261 gagtattcaa ctaaaaaaca aaaagtactt gcttggccaa aagtcaaaga tttgaaaagc
     7321 acgtcaaaaa ttgttgccca ttatcaaaag gtgggcactt atctaggaaa agaaattgat
     7381 tgcgacgtaa ctttttctaa ttttgtagcg cacgctgggg ttaaccaaga cggattagct
     7441 aaaacaatta atgggaaaaa gtattataat tatttgctct ttgataaaaa catttatcga
     7501 ggctttttca tgcagtcaat caacgttatg aatgttaaac tagattttaa gtatgcagga
     7561 tcaaaaacaa aagtagcttt gagtgaacca cagccagaaa ttaattcaaa aatgagatcg
     7621 atgagagcag ctggtattga gttgaatgat acatttctat ctatttacag tttaaatgga
     7681 cagtatcagc aacgtgtgtc ttggtataat gacaataatg aatctgtcgg tgaacgtaat
     7741 attgatatga gagaatttgt tgggtacgaa aaaatggatc gcttacctta ttttgtcaca
     7801 acagatacag catgtgcaga atacaaagct cctgcgttat caacaaacaa tttaacttca
     7861 aaagtagtgg gaggacgtgc agaaaaggct tatagctcga atgatcattt caccgatgtt
     7921 gtaggagctg atacttatca cagaagtggt gtaacgtata cgcttcaagg cgcttcccca
     7981 acattcatga ttggcgcaaa tacgaatagt atgatgttta gctttgatac tgcattgctt
     8041 tggacaccac aaccatcgaa gcctacaaaa gaagtgttta acaaagctaa tactgaagag
     8101 gcagcacaca atattgacaa aaaagtgatt ccacaaggat cagatgttta ctatcatatt
     8161 caccaaaagt ttgatgcatt aacagtcaac acaatgaaca aatacaaatc atttaaaatc
     8221 actgatacct ttgacagcaa aaattttgat atggtatcgg atgggaaaaa ctatgatggc
     8281 gcattgtggt atgttgaagc gaatgggact tggaaaaaag ctgatacagg aggaaaatta
     8341 actgtatcag gtaatacagt cacttatact gcttctgaca gctttttagc taatgctgca
     8401 aattacggta gggactacat tttgcagctc catatgagag caaaaaatga tgcaaaagga
     8461 attgcaccaa atgtggctac tgtaacgttt aacaatgatc cgaacaaagg aacacaaaaa
     8521 acaaataaag tagaaaacta tttctctctt aaaccaaata aaaaagtgga acaagatggg
     8581 aaagatgttg atggtcgaaa tgatggtaaa aaaggaacgc ctacagctcc tttaaatgca
     8641 ggatctgaag tacaatatct agtcacacaa aaatggcata caaaaggtgt agacattgcg
     8701 ctcgatcatt acaagcaatt tagtattcaa gatccagtgg aagctcgttt gacgtataaa
     8761 gaaggttctg cgcgagtgat agatatgagt acaggaaaag atattacttc agaaggtata
     8821 ctaacctatg atagccattc aagaacgctg aaatgggaag cttccgctga tttcttaaat
     8881 aacaatcttt tagatggacg agaaattcaa ctgatattta cagctaaaac tcctttgaat
     8941 gaagaattgg atatcgacaa ccaagcaaaa gtttcagtag aaagtattga gaaagcaact
     9001 aatgtagtaa cgattggggt aaaacctaac ttacctcagg tcattgtgcc aaaaactgga
     9061 tcgaatcatt tagtgctaac tgttattgga agtatattat ttcttacttt agcatcattg
     9121 ggctatgtag ttttaaaact caaataaata taaaaacaag gctgattttc agccttgttt
     9181 tcttttattt gaagattgga ttcgcactaa taaatacatt atctacgcca attctaccag
     9241 cagagtcaac tacaaaatta tgacctaatc cgagaatact ttggttatta taaagtaaat
     9301 ttgcattatg ggcagggcta tttttccatc ctaccatggc atcgatagca ccatcgtctg
     9361 ataaaaggtc atcaatatac agcccagttt gacttatgtt ttctccctta gcaccatagc
     9421 agcctaagct ttccaataaa tcttggaaag taccaccacc agggcgatag tgactgaagc
     9481 tgacttgtaa ttctttagct cgaatatctg cagcctgttg aacaatatca ttgaattgca
     9541 ttggggcaac accattttgt tggcgataat catttaacca agcaagttct ttttgacgca
     9601 taaagttacg taattcgtct aatgaaatct ttttatattt gaatgtgatt gttttatttt
     9661 gatcgacgtt attaatggat cgttggccgt ttttatccac ggtaacggta ggatcgtcat
     9721 ttctgcacaa gaaataattt tgatcagtca tatttttcca aggagtagag aagctatccc
     9781 cttcgtatac tgtttttgat tcactagaga gaacagcgtt ggtatcagca tttacatgat
     9841 taacagtcac attaaattta cgagtgtagt tgaaaatata attttgactt tcagtcacat
     9901 tgtttaaggt tactgaattt gttggttcta cccgatcgtc taaaacatat ccttgaatag
     9961 aaggagcagt taaagtgaca ctttcaccgt gagtgacgtt gattatctgt tctttcaaaa
    10021 tatcaactcg cccctcattt ttgtagttgt tattgcacaa caaattgatt tgatgcactt
    10081 gattataatt gaatgtgatt gttgtattac ctgtgattgt tttgctttga gtatcattac
    10141 caatcacttt gtagctaaaa ttatctttag caccttcgct atatttaaat gcttttgcct
    10201 tagcagtgta agtagaacca gaagtcactt ttgcttgatc tgtagcaatc acttgacctg
    10261 tttgattgtc aatatggtta atggtaacca tatattcttt tggcgtttca ggtttgtgtt
    10321 gcaacccttt aaatgcagca tcaagactat ttttagcatt gtttacttgt gtttgagaaa
    10381 ccttagaatc gtctagtact tttttagcat tggataaagc agtctgaaaa ttattccaag
    10441 attcttctgt aaaatctcct ttagcagttg attttactcg gttgtataaa gcttgtaatt
    10501 cagctttatt cacagtagga actggttttt tctttaatcc tttgtaagca gaatctaatt
    10561 tatttttggc actatccact tgcttttgag tcgcttttga gtcatttaac actttcttag
    10621 cattgtttaa agcggtttgg aatgcgttcc aggtattgtc ggtatagtca ccttttttcg
    10681 ttcccttaac gctcgtataa agagcttcta gagccgattt attcactttg ggtttagagg
    10741 tgtcagcgcc ataccaaccg ataccttcgt atttccagcc atagtctttg gttaaccatt
    10801 gtacttcttt ccaacttgca gtgtagtgat gtgagccaga ttttacacca ggaaggaaaa
    10861 ggcggtagat cggtttatta tttttttcgg cagaacgcca ggcaggccct tcataagtcc
    10921 agccgtaatt tttagtcaac catttcactt catcccaact agctgtgtaa tggtgatcac
    10981 gaagaccttt attgtacaaa cgatagacaa gatggccacc gctagtcggt gcttcccagg
    11041 cggggccttc ataatttccc cattttatct ttactagatg gtcacgttct tttttgctag
    11101 aggtgtaaaa atgttcatta ttatttggat tgtaaaggcg atacatgacg ttagttgaag
    11161 cagcgtcaac agatccagca agactaagtg aggcagcaaa tgttccaata gctaaaacag
    11221 tttttggatt aaataatttc attttttcaa ctcctaaatt taattaaaaa tgtttacatg
    11281 attattatat atcggttaac cgatatagtc aataaaaaat aagaaaagcc ttatataatt
    11341 ttggcttttc ttattttatt tgttagttga agtattaata tcaacgattt cttcagccaa
    11401 tttatttaat ttcatagcat ttatgaatct catgttgtct atactagagc gtttgttggc
    11461 aaggtcactt actgtagtta agggtacgcc agattctatg gatatagaac gaactgattt
    11521 accactatca aacagcaacc attcgatttt ctttttatca gcgtacattt caatgctcct
    11581 tcttgttttt tctttattat agctcttttt tgtaatgaat cacaatatca agagaaaaat
    11641 tttctataga aaggtggatt tttatgagta ttcgttctcc gtgtatccaa atgaggtttg
    11701 ttgctacttt cgttatttga tatactaaaa ataaacaacg aaagaaggaa taaaatgaag
    11761 aaaaagcaac tatggtttgt ctctatgttt gcaatatttt ttattatttt aagtggatgt
    11821 tcaagtaata agaaatcgga agctaaagaa gataatagtt tattgcaacc aggaactgtt
    11881 tggaaagaag aagtaggtgg tcttattcat aatttaaaaa ttatagatga tactacctgg
    11941 gaatattctg aaagtgtatg gcatccagat cctgtacaaa taacagttaa gaggcaaaaa
    12001 gactatgaag gtttagaaag atacaaaata gtagattctg caggcattag ggaatttata
    12061 aacaaacctg attcattatt tattgttgtt ccctatgaga aggatggcgt aaaaaaaata
    12121 atttttcttg gatctagcaa ggatgagaag cgaacgaaag agaaattaat tcatgatgga
    12181 tcacaatcaa ataaatacaa attacaaaag actagcgagt gattgctagt ctttttattt
    12241 gtcctgaagg aggaatcaca gtggcaaaag ctaaaacgcc atttgaaaaa gccgcgtcta
    12301 aaatcttaga acgccgcggt gtatctgaaa cacagtggaa acaagaagtc cttgaaaaag
    12361 cacaatttga cctattacgg ggaaaagaca aggacttaga aggatatatc tatcaacgtg
    12421 aacgtgaaaa gcttgttttc gatgaaatta ttaaacacta aaaggagcga acaattttat
    12481 gtttgaatca attacaatga attttttaac acaaccgaaa gtagtagctg cggttgatat
    12541 ttttagagca ttacaaactg ccgcaactag tttgaaaaat aatctgatga tttttgctgc
    12601 tgttgcggca gtggcttcca ttgctcttgg aggtattttc ttcttctttg ggcgaagagg
    12661 agctgaaaac gggaagacac acgtaggtta tgtattgttg ggggtaggag ttattttagc
    12721 tgccgcttct attgtagttt caatgttctc aatgtttgga caaaccccac aaggactata
    12781 aaaaaacaag tagaaggagt aaaaagtacg tggctacttt ttactccttt ttttatggaa
    12841 ggagaatatt catgtttttt acgatttcag gcaatgcaaa attggataaa gagttaataa
    12901 gaaaagcaac gaagaaagtg ggaaagcgta cttccttttt accgaaaaca attaaatatt
    12961 ctgtcattga aacggaagaa cagctacatg tgttaggaca agtgttagaa caagagaatc
    13021 aatcttctgt taaattgact ctcacgttac atgataaaga aggaaaaata gaaaaggctg
    13081 gcacagaata cgtttttggc tcactggatt atcaaatttc agaaggtttt tatcctacat
    13141 tgattgattt aatccgccta gatatattta aagatacgga tgaaaccatg agtgtggaag
    13201 agtcttatcg aaacgaaaaa attttacaag ttttagaaga agagttagaa agcgaccaaa
    13261 gaaaagtgaa tcaagtgagt gaagtcgaag caaacgaaga agtaccatgg gaacgcccaa
    13321 tctttccaaa ggatgaatca aaagaaaaag agaaaggaat tattgacgaa caagctgaca
    13381 ttttgactca taaatcaata tttgaggaag agaacgaggt aatgggtcaa ttggaggtag
    13441 atccctttga agaaacaatg gaggatgaag agacggccga agtagaagtt gatccagttg
    13501 aagctaatga agacccaaca tggactgaag gggattctca ggaatatatt gaaccactta
    13561 tcagtgaaga agtagagaaa aatgaaacag agatacaaaa ggcaacggta tttgattata
    13621 ttttggatca atatccgcca gagcatgaat ggatgaaaga aaaaaataaa ttatttttaa
    13681 atgaacttta ttcgaaatat caattacctc aaacctatca agcattttta gagagtaaag
    13741 aagaattaat ctcacagggt aaaggcacac ttttagaaca gttagagtct gtccaatcaa
    13801 caaattggca tgagcttgca caagaagatt tattagctac ttttgaagaa cgtcaacaag
    13861 aaacagatca agaaattaat gagtatgcga cggaacagtc gtcgaattgg gagaaagcaa
    13921 aagaggaact aaataaagaa gaacagcgag tgattgaaga agaagtacaa aaaattaaag
    13981 agcggtacga aaagaaacgt gacaatgcgt attccttgtg tgtagaaaag atcaacaatt
    14041 ttactcagac gaatcaagaa gcattatcga aagaaaaaga aaacttatta aaagaacgta
    14101 taaaagaacg aaaagaagaa ttttaccgag ggttgcgtac tgataagcta aggattagca
    14161 aagaattaaa tgaacaactg aataaactct atcaaactac gactgaagtt ctgatggaaa
    14221 aacacgagca gatccaacaa gaattacaag cacaaattcc aaaatggaaa aaagagtatg
    14281 aaattcacca acaagaattg aaagaacaag aagaaaaaca acggaaaaaa gaaaaagagc
    14341 gcgaacaatt agaactaaaa aaacgtgaac aggatcttgc ggaacaaaaa atggcgatag
    14401 aaaaacaacg gctagaacaa gaaaaggaaa aagaagcagc tgctcgtaag gaacgtcaag
    14461 aacaaatgga tacattgcga caagcacagt taaattatct gacacatcct caaccagtag
    14521 ctgctgttca aacgccagtg aacaaccaag caaatttaac tccttcaccc cagcgttcct
    14581 ttaacggatg gatggtggga tgtattgcaa gtttaagctt gcttctaggt ggaggaacag
    14641 tatttgcttt taatcatatc aatcaatctt cacaggctga ttctgtagcc acaacggcgt
    14701 caatcaagga agaagcccag gaacaagcaa gaaaagagta tgaacaacaa ttagaagaat
    14761 tattgaatcg taccaatcag tcaacaacag agtcaagcat ggaaaatagc aaagagagtg
    14821 attctagtaa ggctaaagaa ggatcaagcg attcaactgt acaatcaaac acttccgaaa
    14881 gttcagaatc aaatgaggtg aaataatgcg tgttagagaa acaacgaagc gaaaagacaa
    14941 acgattcaat ttagaaaaga ataggtatct ttctcatttc tatcgctata ctccctcagg
    15001 agaagagcta ccagaaaaac atgacaaacg catttcgaaa aagatttttt atagtggact
    15061 tgtatacctc cctttagagt atttagtaac aagagtacca gaagttttca accgattgga
    15121 aattgttaag ggaagcttac aaggaataaa tctgtttcaa ttacaggaaa tgccacaggt
    15181 ctttcatttt gattcagctg gtttttggaa tccatttact cctacaacta gtttgggtac
    15241 acgtttagca atttcgacag tttgtgtggt tccagctgta cttatgggat tgaaaatgga
    15301 catgtggttt cgtcctctag cagatggaca aaaaggggat aatcgattaa tgaccttaaa
    15361 agaaatccaa cagatttatc cgcaaatacc tgaaacaaaa actacttttc caggttatgg
    15421 aggtattcca atcacacatt acaaaaaata ttggtacatt caaacagata ctgttaatac
    15481 gtgtattgtt ggtacctctc gatcagggaa aggtcagatt gaagtgttag ccaccattga
    15541 caatttatct cgtgcagaaa aacaaagttc aatggtcgtt aatgatccaa aaacagaatt
    15601 atatgttggt agtaaagatg aactagaagc tagagggtat gatgtatatg cctttaatat
    15661 caccgatcca ctgcaatcaa tgagtgataa tccattggca ctcatcgtga aatactggaa
    15721 acgaggagac atagatactg caacacagtt aaccaatact ttcacaaata cgatttatta
    15781 tgatgccaac gcttcagata acaaatactt taacgaaaac gcgcagaaag ctgtcaatgc
    15841 gcttattttt gcgttgttag aacaagctga tcaaacagga gattactcca aattgacacc
    15901 gaataatctc gttgagcttc tttctgagat tggcggtttt aattattatc cagatccaga
    15961 caatgaattc aaacagttga atgccttaga tgaatttatg aatcagttgc cacctggaaa
    16021 cattgcaaaa aaacaatatg gggcaacgaa aattggatct gataaagcga agggaaatat
    16081 tttatcaacg gcaatcacgg gattgaatcc atttactcta acgaaaattg caaagatgac
    16141 ttctcaatca acgattgatt ataaatcggt tgggtttcca aaatacttag atttgaaatt
    16201 acatgaaagt cttttaaatc aacgagtcgt agtagaattt tatcataagg gaaagaaatt
    16261 tcatgaagaa cgtgtcaaag taggctataa aggatttagt gaaatcaatt ttgattgtca
    16321 tttagttgca ggtgatcaag tttgtttaaa atacgatcat caaggaaaag aatatgtggc
    16381 ttggtatgaa ttttctcaaa gagtattgaa agacgaagag ggtaatatcg tttatcggaa
    16441 aaaacgagga gaaacccatt tgccagaatt agaaaaagaa gccgttctaa cattagatga
    16501 ggaaaaaagt aacttattag tagagtctat tcggatgcac tataccgata aaccaatggc
    16561 tatttttatg cttacacctg attatgatcc atctaaccat atcattgtta gtatttttct
    16621 tagtcagtta tataaagaat tatctacgca atgtgttaag actaaaggag ataaatgtca
    16681 ccgcaggatt cattttattt tagatgaatt tgggaatagt gtgacctgtt tagcctaagg
    16741 ataaaagagg ctagttccaa cgaacattgg aataacttta ctatcgagaa atcaaatgac
    16801 ggggtaacgc cctgaagggt ttccactgat actgcgacat gcgttagtag gatgtgcatc
    16861 caaacgcgta tgaagctcgc tgaagtcggc agaagggtac cgtaaggaaa gacacgatac
    16921 gtatctacca cgcaagtgct ctagaggtag ggtatgtacc tgatatgtcg ggtgtcctaa
    16981 aaagttcaat aaggtgagaa tgatttgatt atctgacaaa cttgcgaatg gaatgtctga
    17041 aacgaataac tcatagaaat gtgaggggga agggggatac gtcctctttc cattgactcg
    17101 aggttgagta aaaatgtgtt tctatgaaaa accttgcatg gttaaaggct atggagtagt
    17161 caacaggcaa aagcaagcac ctaagttgaa atctatggat agatagtaag gaacagggga
    17221 agcatctagc acggagggag cataccgaag atgtgtttct aaggaaaaac cgaaatcggt
    17281 tataacttag gtgaatagat gtgaaagtag agccacgacc agtgaaaatt tcgtaatgaa
    17341 attggaggaa caggctcaag tcgttattta taatataaga aacctattta aaatcatgga
    17401 ttctcgtaag actaaaaagg tcacgaacca gaatggagcg tgataaaacc atgactaaca
    17461 caaaaggaat tagcttaaag aacaaacaac tcagacacgc cgaatactac gacatgactg
    17521 agactttcga tgaattgcac gcaatgagtg ttgcaaaatc aaattttaaa aatctcatga
    17581 aattcattat tgatgacaat aatatctttc tagcgtatag aaatatcaaa aagaataaag
    17641 gaagtgcaac ggccggatac gatggtgtca ctataaaaga cattgaaaaa ttggcatgtg
    17701 gtgacttttt aactattatt aaaaggcgat ttaaggatta cagaccaaga aaagttaaaa
    17761 gagtagagat cccgaaacca aacggaaaac ttcgaccttt aggaattcct tcaatatggg
    17821 acaggatagt ccagcaatgt attctacaaa ttttagaacc aatatgcgaa gcaaaattta
    17881 ataagcatag ctatggattc agaccaaatt gttctacaga aaacgccata gcagattgtc
    17941 ttgctagaat caatcaaagt aagatgaatt atgttgtaga tattgatata aaaggattct
    18001 ttgacgaagt aaaccatacc aaacttatgc gtcaaatatg gacaatgggg attcgagata
    18061 aacaactcct tgtaattatt cgtaagatgt taaaggctcc gattgttatg cgaaatggca
    18121 atgttgtttt tccaaccaag ggtactccac aaggagggat tttaagtcca ctgcttgcga
    18181 atatatgcct gaatgaattt gattggtgga tagctaatca atgggaggaa cgaactgtca
    18241 aagagctgaa acaccactat cgaaaaaacg gagcatggga taaaggaaat atctattcga
    18301 aattaagaag ccacacaagt ttaaaagaga tgtatctggt acgctatgca gatgatttta
    18361 aaattttctg ccgaacagga gaagaagccc aaagggcttt ttatgccaca caaaaatggc
    18421 tcagagaaag attaaagctc ccaatttcaa tggagaaatc taaagttacg aacctaaata
    18481 aagctgaaag tgaattcttg ggtttttcaa taagactcca caaaaaggga aaaaagaaag
    18541 tggctttcac gtacgtttgt cgcaaagcag aagaaaacat taaaaataaa ctaaaacaac
    18601 agattaaaaa aattcaatac gctggagcaa aaaaaaatag gcaccgagca ataggtgact
    18661 acaacatgat ggtcatcggt atccacaatt actatcggat agcttcacat tgtagtgtca
    18721 atttcactga gatttataga agtgttagga cagtaataga agcaagactg aaagctagag
    18781 gaatgacgaa aaatggaatc tatggacaag atcatgaagg ataccgtccg tatctaaagt
    18841 ctaagcaaat gagatatatt gaaggttttc cgatacttcc aattggctat attaaaaaaa
    18901 gaactccact caacaagcgg agaaatctaa ataaatatac caaggaaggg agaaagctca
    18961 ttcatcaaga gcaacaagct atagaaagct ggaaaatcaa gtatcttgta aaaggtttta
    19021 gtaacaataa gaaatacacg gtggaatttt ctgataacaa aatatctaag tttatttccc
    19081 aaaaagggaa atgcgctatc acaggaaacg aacttttgat ggaagaaatt gaatgccatc
    19141 acattaaccc atatcatttg tccaaagacg atagttacaa gaaccttgtc attatctcta
    19201 gagaaatcca tagattaatc catgcaacta gtgaagaaac tattctgaaa ctgcttcggt
    19261 tactgaaact aaatcactat caaattagaa aactaaacac gtatcgaaaa aaagcagcta
    19321 attttccaat atcaatcaaa atgaattaga taggaaacaa attatattgt aattaacgat
    19381 ggaacgccgt gtgcggtgaa agtcgcacgc acggtgtgga ccgggggaaa agacggagat
    19441 aatatcaaac tcttacctat cggaattgcc accaatggat aatatggaag gaatcatgac
    19501 ggtcacagct ggccgaaaca tgttgtggga tctgtttatt caatcttatc agcaacttta
    19561 tgcgaagtat ggagaacaaa acgcagcgat tatcaaagaa aattgtcaga cacatattta
    19621 tattatgtcg acagatgata ataccatcga agaattttct aaaaaagtgg ggaataagac
    19681 ggttgaacaa gagaacagta ccatcaattc attaggtatg aatactcata tcaatcgcaa
    19741 tgttgattca gatcgtatct taactcctga aagaatttct acttttttag aaggtgaaac
    19801 gattgtactc gctcctttaa aacgacaaga tttgaaaggt cataaaatac ggccgtatcc
    19861 tatttttaat catggggaaa cgaatcttcc ttatgcttat caatatattg aagatttcaa
    19921 tccatcgtgg gatatcaatg atatagacat acattgtaca catgcggact tggatcttaa
    19981 ggctttacaa attgattatg attatttcct accagatgaa tatgctagaa atctctatca
    20041 tggactgcat gatcaattag aagaaaaaaa cgaagaaaat atgttttata aaatcgttca
    20101 atctcttgag aatgagacgg ctaaaaaatt gttaattcaa ttttacgaag aacaagcagc
    20161 agatcgactt caagaatatg ttgaaaagtt gatcaaaaat gaagaaattt ctgaaatgat
    20221 tgggaaacgg ttgttattgg aatctgaaaa ggtggtgaaa gaatgatcat tggaggaatt
    20281 ttttctggca tagccgactg gtggtcaggc ttattcggag aaggggatgc aaaccccaaa
    20341 accgtaacga aagtcttaca agattatggt aattatctgc agtatcaaga tgtgttcagt
    20401 tggatttgta atactttttt atgggggttg atcaaagggt tatataatct caatacttta
    20461 ctagaaaaaa ccatttatca aagctttgat ttaaaagact tattgaacgc cgctggggta
    20521 aatgaactat ttcaaagttt gattagtaag gtattggctc ttttttgtgt cgtcacatta
    20581 atttatttag gcttgaaatt ttttatgagt aaacacccac caaaagtcaa aaatatcttg
    20641 gttaatttat ttatggccat gatcttgatt tttggtggta gttctttaat cgatgaaggg
    20701 ttaaatatca gtaaaagctt ttacggagac gtcactgcag caaataaagc agataaaacg
    20761 ggttcacctg cttttcaaat tattcaaaat aatgtgatcg atgtcagtac attactagca
    20821 actgacccga ataaagtaga atccctgcca acagacaaaa gaaatgcttt aacagcgaaa
    20881 aattttaaaa cagcgaatat caatgggatt attactccta aacaagctaa agaaatggcg
    20941 gataaagata agagtggttt atcagattta caaaaggatc ggttaagagc gttacaatac
    21001 cgactggaac tggatgataa tggaaaagaa attcctgtgc aaatcagtga tgaaggctta
    21061 gccaaatatg tttatacttc agggtatcgt cgatacatta gtagtccagg gattatttta
    21121 gctggtgaat cttctttggc ggtggcctat ttatttatcc tatttacgat cgttacttgc
    21181 attattgagc tggtatttaa aaaattctat ttagtgattg ccgcgtcaac ggactttgag
    21241 acaggacaac ggatgaaaag tgctatcgaa gatatttctc aatccttctt gttattggca
    21301 tttacaattt tagaattacg aatctatacc ttaatgcttt caggtattgg tgatttgcat
    21361 gcggcaggaa agatcaatgg attcttgtat gttgtcgctt tgattgtact aaccattgcg
    21421 ctattcaaag gctctcaatc agttacgaaa attttcggcg ttgatacgag tctgaaaaac
    21481 ggcagtaatt ctcttcttag catgtttgcc ttaggaaata ttgcgaaaaa tgtgggtagc
    21541 ggagctaaaa accttgcaag tgctggtaag agtggtttaa gccatttaaa tgatattcgt
    21601 aaaaatggat ttggccatcg aaaagatgtt acccctgata acggggaaga acaatcagac
    21661 gataaagcta caactgtacc taatagtaag aaaacagttt ccgaaatgtt cgggaaagcg
    21721 aaaaatggtg tttctaaagc cgcagaaggt cttggttacg tcaatgaacg tgggttaaaa
    21781 ggaacagctg aagatcttac agaaaaagcc aaagacacct tagaagataa attagacggc
    21841 acgagagcta aagaattggc tgaagctgtg aagaatccat ccgaagcact agaaaaacaa
    21901 aaagaaaaag cttcagaagt caaagaagga ctaaaagatg cgtatggtga aggacaagtc
    21961 aatgcagcag tgaaagctaa tacaacaacc gaaaaagaaa atcaagaagg tatagtgatt
    22021 ccttcagtca aagatcacca agaagcgttg cactctaatg aaaattcgat tgaagagaaa
    22081 aattccatag aagaaagaaa ttcagaagaa ggaaaaaatg gacagttacc aaaaactgat
    22141 ccagaacaat atcgctataa acctaacagt gaccttgaaa atgagaagcg aatttcagat
    22201 ttatcaaaag taaatcaaga agacaaagca gaaaatgagg gacagttacc aaaaactgat
    22261 ccagaacaat atcggtatag atctgttaac tccgaaaatg aaaaacgcat ttcagattta
    22321 ccaaaacgaa atcaagaagt acaaacggat gaggattcca tcgttctgcc aaatgataat
    22381 ggaatcgaag ttggaactga aaaatcaacg aaaattggtt tacctaaggc acaaaattta
    22441 ccaatgaaag atagtcgttt gaatcaattc aaggataatg atcaaagttt tgttcatcaa
    22501 tcacctgcag gtactgttca aatgaaacca agtcgtttgc ctgaaaatgg aaatctgaca
    22561 actgtttctt acaatttatc tgaaagtggt gagacaggga atgcgtccgt tcaaaatgtt
    22621 gtgacaagag aagctgcacc aaaacctatt caaaacgttc atacaggtta caagccagca
    22681 aatgtggcat ttactgcacc aacaaaaata aatgtgacaa gagaaactaa aaacaggaac
    22741 aatgcattga aagaacaact attgagggat atcaaacagg atatcaaacc ataaaaggcc
    22801 tacaagttag gccttttctt tatatgaaaa ggagaaatca attatggata aatatataaa
    22861 catgaaaaac cctccaagat ttagtggaga atggaagttt ttcgcttttt tctttttaga
    22921 tctattaacg cttggtggct gctttttttg ggcgaaaatg gtcaataatc ttgtccactt
    22981 accactcttt tttgcactct tgaattatgg cttatggatt gcgatagcgt tagtgattgt
    23041 ttggcgaccc tataataacc caggtcaacg acaaattttt gcgattatcg agtctatttt
    23101 ttttgcggac aagaaccatt atcatgcgtt agatcctaac cgaaattatc atggtacgta
    23161 taaggaggat gaataaatgc gagtcaaagg acaaaattca gttgaaagga aatccatttt
    23221 gcagtttgga aaaccagaag agcgctctat cttggactta tttccgtata aatcctgtac
    23281 agaagaggga gtcttaatta ctagagaaga tcattttcaa cgttattatc gtgtagtttc
    23341 tacagacgtg gaaggattaa atgaacaaga gaaactagaa cgaatgaatc agttgaccac
    23401 cgtcatgcgt acgtatgtgc caacaattaa gttagttagt ttgaccacag agacggatct
    23461 aacggaacaa atcgtgcaaa agcggcagtt attagataaa aatcgtatgg aacagtcctt
    23521 aggaagaaat ctacagcgat taagaaaata tgaaaagaaa ttagtagagg aaatccagga
    23581 attgaaacga gcagaacagg aacgccctga tttaagcttc tttttcgtca ttgaaggaaa
    23641 gacaatcaag gatttgcaaa ccagaaaccg tcagttaatg cgatctagtg gcattttagg
    23701 gttaaaacca ctctacaaaa aagaattgat caagattctt tatcgaatga ataatatgaa
    23761 tgatgagtag gaatggggaa gagagaatga aatatccgtt gatatggtta gaaaaagatg
    23821 ttccgaaaga agagaccact agaaaatttc ctcacacttt aagcctgggt aagttgggaa
    23881 aaggaaaatc ttttaaccaa gtaaagaatc aaacaagaag aggtgactgt acatgttaga
    23941 agcaattaaa acagcttttt caccacaaaa tgatcaaaag gtacttgatc cattaaagca
    24001 actaggaaat cgggaaatag aaattttaaa atccaaaggg tatgatttag actttttaaa
    24061 acaagtgatg ccacaaggtg gattaaattt cgatgaagag tatgtgacct atggaaatgg
    24121 ttattcacga tgtgtgacag tttatcacta cacaaaaaat cctacgcttt tttggttggc
    24181 caatctcatg aacaatcctc atacagtggc aacactagat gttagcacag atgaaaagca
    24241 aaaagtgatt gatcaaatca atcgtgcctt agatgaatta aatgatcggt cagataatga
    24301 acgaaaagcg actgaccgaa ataaaagcgc ggaagaatac ctagaactag cggaatatgc
    24361 ccgaaaattg acttctaatg gggaaatttc taaacaagtc aaagtgagag tacatgttta
    24421 cggaaacacg attcaagaag tagatgaacg agcacaggaa ctgatcgaaa atctcaaagg
    24481 gatggattat cgtgcagtga cctatctgca caaaacgaaa agagactggc aatcgatgtt
    24541 caccatgttc gatgaacaag ctgaatggtt tggaaatatc aaagggcaat cactaccatc
    24601 gctaaacatt ggcggaggtt tcccgttcca ccaccaaacg ctaaaagatc caggtggaac
    24661 acaatatggg gaaaccatga caggcggccc gtttgtttgg aatgccacgt ataaaaatag
    24721 tgtgcggttg tctaccaata ccttgcttct aggaatgatg ggagctggta aatcgaccgt
    24781 tcttaaaatg atcgcggaag cccatttagc tgcaggagac tttatttggg gctttgaaaa
    24841 gggaaaagac tttattccct ttttaaagga atataacggc attatggtgc gtttagacgg
    24901 atctgacggg atgatcaatc ctttagaaat atttgccaca cgtacgtatg atgaagcttc
    24961 cagtttatat gacgatggat cagtcaaaga tttgaagatc aatgaagcag cgtcctatca
    25021 aacgcactta gacaaagtgg tctatcaggt acagttagtg agtcctcagc taaaaggaac
    25081 gatgaaagca gaatttaaga cctatttaaa tcgtttttat gaagagtatg gaacagtacc
    25141 acgcggcttt acttcctcaa attcgcgttc aaatactgat acgcaagtca caggtaaaga
    25201 tccagaagct tatccgacgt tcaaagaatt tttagacttt ttaggacaac tggaattacc
    25261 aggtgcttcc caagagaaaa agaatcgaaa agaagaaatg gaatccatcg tagaatcctt
    25321 atgtgagacg tatggcatga tttttgatgg tcatagtacg attcgacacc ttgaccaaca
    25381 acagttggtc ttttttgaca ttgactctat tacaggctta gatcgagggg tacaacaatg
    25441 tcaaatgtac atggctatga cgttgatttg gaatcaggca ttgattcaag gaagaagaca
    25501 acgacgttta attaaagaaa aacaaatgga agaacaagac ttcaaatgct tcttggcgat
    25561 gattgatgag tgccataatg gtgcgacctg ttctgcagtg aaaagctgtg ggttgcaagt
    25621 agtctaaaaa ctattgtaat aactcttata acgagaagtc aaatgagtgg gtaacgccac
    25681 aaagggcttc cactgatact ccgacatgca acaagtagtt tatgcagacc aacgttgtgt
    25741 gaagctcggt gaagtcggct gaaggatacc gtaaggtaaa agaaatagtg aataccacga
    25801 aagttcttta gaggtaaagg gtgtatccga taagtcgggt gtccaaaaaa acttaatatg
    25861 gtgagtatgt acaaacgtac tgacgaacta gcgaatgtac tgtccgaaag gcatagctcc
    25921 tagaaatggg agagacagtg agcaaaaaat cactcattgt gctaacttgt ggttgagtaa
    25981 aagtcgttgt tatgaaagac catgctgcgt tacaggcgta ggagaagtta gggggcaaaa
    26041 gctagcatct aagttaaggc atgtggatag atataaggga acaggggaag ccatcaacat
    26101 ggagagtgca tactcgatga agtggtagta agaaatatgt gaatgacaaa taacttactt
    26161 tagtgatggt gaaagtagag tcacgactga tgaaggttct gtaatggaac tggaggaaca
    26221 ggctcgattc gtctgtaaaa gtcatgaaac ccgttcaacc atgggattct cgtatgacta
    26281 aaaaggtcac gagccaattg gagcgtgata aaccatgaca aaagaaacaa gtccaaaaga
    26341 taggaagttg cggcatgcag aatattatgg catgacggaa atcttcgata agatatactc
    26401 caaaagtttg aagggagata atttcaagaa tctaatgcag attatcattt ctgataacaa
    26461 cattgtccta gcatatcgta atatcaagag aaatcacggt agtgtgacaa gaggagaaga
    26521 tggagtaacg attaaagata ttgaaaatct caaccgtaat gaattcgtag aaattgttag
    26581 gaagcgattc gcacattata accctcggaa agtaaggcgt gtagaaattc ctaaatataa
    26641 tggtaaatta agaccgttgg gtattccatc aatatgggat agaatcgcgc agcaatgcat
    26701 cttacaagta ttagaaccaa tatgtgaagc aaaattcaat aatcacagct atggtttccg
    26761 cccaaataga tcagcagaac acgcaatagc agattgtatg gcccgaatga atcaaagtca
    26821 catggaatat gtggtagatg tagatatcaa aggtttcttc gacgaagtca atcatactaa
    26881 actcatgaga caaatctggt ctatgggtat acgagacaaa cagcttctct taatcattag
    26941 gaaaatgtta agagcacccg tagtacttcc aaatgggaag ttgatatacc caacaaaagg
    27001 aacaccacaa ggcggaatac ttagcccatt acttgcgaac atcaatctca acgaatttga
    27061 ctggtggata gcaaatcagt gggaggaaaa agatgccaaa gagctaaaac atcattttag
    27121 gaaaaatgga gcttgggata aaggtaatat ctatcacaag ctcagaaaga gtacaactct
    27181 aaaagaaata tacctagtga gatacgcaga tgattttaaa attttctgta gaaattataa
    27241 tgaagcgaaa aaagttttct atgcaactaa aatgtggtta caggagcgtc taaagttacc
    27301 aatatctgaa gaaaagtcaa aaatcacaaa tctttcaaaa gaagaaagtg aatttttagg
    27361 ctttacgatg aaattagtga ccaaaggtaa caaaaaggtt gttaatacgc atataggtac
    27421 aaaagcacaa agcatgatta aagtgaaact aaaaaaacaa atcaaacgaa ttcaaaaaag
    27481 tcctaatagc aaagatacct ttatctatat tggagtctat aacagtatgg ttattgggat
    27541 tcataattac ttcaaaattg cgactcattg tagtgtagca atgcgaaaaa ttgcaagaga
    27601 actcagacca agttttgaaa tacgactacg agaacaagga atctcaaaag aaggacaata
    27661 cggaaagtac gaaggataca agccttacct acggtcagga caaatacgat atataagagg
    27721 gtttccaata ttaccagtag ggtatattca acacagacat ccgatgtgta aaaaaagaaa
    27781 tattaataaa tacaccgaag aaggtaggga agccattcat aagaagcaac aaaccgtaga
    27841 agaatggaag atatcgtggt tgtgtagcaa tccagtgctt agtaagagag caacgattga
    27901 atttgcggac aatcgaattt caaaattcat cgctcaaaag ggaagatgtg cagtaacagg
    27961 tgaggagctt atcttatctg aaatgcattg tcatcatatt atcccttatc atgaaagcaa
    28021 aagtgatagc tatgaaaacc tagtgattgt tactgaggag gttcatcggg taatacacgc
    28081 tacacaaagt gaaacgattg aggaacttct aaaatatcta aaattaaatc caaaacaaaa
    28141 agaaaaactc aatgagttga gattaaaagt tggtaacgaa gaaatatctt aataaatatt
    28201 tgtaggacgg gaaaacagaa tgtcttttat agacgaggga acgccgtatg cggtgaaagt
    28261 cgcacgtacg gtgtggactg ggggaaaaga cggagataat atcaaactct tacctatcag
    28321 tatcgattaa tccagatttt attgaaacgg taaattatgt cacaaacttt caacgagaaa
    28381 tgcgtaaagt agaagcaatg actgttttag ctacacaatc cccacaagaa atggtgccag
    28441 aaaatatgtc ttctgataac ttctcgaaac tgaagaaagt ctttgaattt tcttctacga
    28501 agatctttat gcgtatggat gaatctattt tacgtcatat agaaggatta gttggtaaat
    28561 caatgacaaa ctcagaatta gaatccattc ctcaacaaaa tcaaggagac gctgtgatca
    28621 attttggctc aaaagaaacc attcgtgttc attttagtcc gaacaaacgt caattaaaat
    28681 tgtttgatgg aggaaaataa tggaaaacca aaatgaaagt ttaatcaagc agtatgttaa
    28741 gcgtcgtgca aagcgacgct tatttttgtg gttgtttggt acttctgcag gtttgattac
    28801 tattttgatt actgtgttcg tgaccctttt tctaatactt gcggcgggtt cgattgataa
    28861 ttctgattca gattcaagta gtggtggcga agcttttaca ggagaatatt cggaaggctt
    28921 accgatttat aaagaaatca aaggaagagg ccctttttct gatgagattg cgcaatatgc
    28981 tgtaggtgca gcagtgaaat ataaattatt accaagtgtg atcctttcgc aatacggtta
    29041 tgaatcagcg tttggtacgt cggcgtccgc aagaaatgat ctcaactatt ttgggattac
    29101 ttggtttgat ggttgtctgt ttcctaaagg aactgcgcga ggaatcggtg gtattgaagg
    29161 tggctggtac atgaagtttc ccaactcaaa agcagccttc tcctattacg gctttatggt
    29221 agccacacaa tccaatttta atgcatgtgt aggaaataaa agccctggcg caagcttatt
    29281 gatcttagga cgaggtggtt atgccgctgc aggaattact gaagatagtc cgtattatac
    29341 aggttgtatg tccattatca cttctaataa attaaccgaa tatgatgaat tcgccatcaa
    29401 acattggggt gaaggtggca ataacaacgg cacgatcact ggtgaatgga cgaatccatt
    29461 ccctggcagc agtttagata aaagttcctt cagtggtggt caattatttg gaacaaatcc
    29521 aggcggtgaa ttccgtccga atggcttcca tgatggatta gactttggtt cagtcgatca
    29581 tccaggaagt gaaattcacg cggtgcatgg aggaaaagtc gtgtacgttg gcaatcctgg
    29641 tatttcaggt ttaggtgcat gtgtgatcgt gattaattac gacggtttga atatggtata
    29701 tcaagaattt gcgaatagta caggaaattc tcgtgtgaag gttggcgatc aagtgaaagt
    29761 tggtcaagta atcgggatac gagatacagc acacttgcat ttaggtttca ctcgaatgga
    29821 ttggcgtcaa gcacaaggac acgcattcac agacgatggt acatggattg atccattacc
    29881 atctttgaat agcagcaaaa aatagatcag gagaaaaaat atggaaaata aaactttaaa
    29941 aatcgtctta acagctgcaa ttagcgttag tttaatcggc aatatcgcgt tgttttggca
    30001 gctgaaagaa gaacaagaga caaatacctt taaaattgaa gaagtggcta aaaacgcgtc
    30061 tgagaagctc aaaaaaaatt cctctgaggc acaggcgaag atcgacaagt taaatcaaac
    30121 catcaatgag aaaaaccaag aaatcgatca gctgaagcaa caagatggca caaaagcaaa
    30181 agaggaagta actgaagcac aaagaaagac ggcagaagag ttcggtcaat tggccattga
    30241 taaatcatta agtagaaatg aattaacgga aaaactaaaa gatgtcgcaa cccaagaagt
    30301 gatcgacaaa ttaagtcctg cagacgatga tcaccaacat gatgattacg gaagttactc
    30361 ctttacatta ggtgacgtgc aaacttatgc tcaaacaagc agtgtaaaag aggaacaaaa
    30421 ttttgtcgta tttgttgatt atacaatcgg caatccgcaa ttcaaagatg tcaaaccaca
    30481 aaaaataaaa ggtggattaa ctgtcactga aaaacaagta gatggtcaat ggaaagtcat
    30541 agactttagt tatttcactc gttaggagga agaaaatgag taagaaaaaa ggagaaagac
    30601 aacgtttcaa aaaacgaaaa agttatcttc aatggctggg aatctttatg attctcggct
    30661 ttttgattct tgctagtccg atttatacga atcagaaggt agatatacca gatgaggtaa
    30721 gcacgaacgc ctttttaaac acgaaagagc tgacaatggt ttcaaaagaa aaaggagcga
    30781 accagcaatt agtttttgaa tttgcgatcg atgatgaaga tcaaagcttg ttaaaagaac
    30841 tggctaatct taattatcgc gtagaagtaa agacagctaa aggggattat caagcaatac
    30901 gagccaaagt gatcaaggtg tctgatgatt attttgcagt gaagctaacg catgtaccag
    30961 aagaatatat cgccatgcgt ttaaccatta ttcctgaaaa aattgatcca aaagtggata
    31021 tgcaagaacc acaagatctg atttattacg tgcacgaaga taaggttaaa gatcaagtga
    31081 aagatgaaga ttatgaacaa cacgcgatca attacaaagt gaaaggatac aagaaagaac
    31141 aaaaagcagc tcaaaaacaa atggaatctt tccaagcaac cattgatttg aatgaagaat
    31201 tagtgaagaa gctaaaagat caattgcctt atcaagtcgc agatgatcag gaaaatactg
    31261 aaaacaagat taatagctac cagcaagaaa ttgaaacatc gaaaacgcaa ctgaaagatc
    31321 aagaagagat cattcaaaaa cttcaagaaa aaattgatcg tatgacaaaa gaaaagattt
    31381 agaaggacag gtggagtgaa aaaatgaagc gaacaaactt ggctgacaaa gatactttcg
    31441 ctgagcagaa agtattgatt aaagcctatc tcaaagttgt aaaagctaaa gaaatatgtc
    31501 gagaagtgaa tttatctaac acaacaatat ctgagttgaa gaatggtcga aagaatttag
    31561 atactttaaa attcagatca tttgaagctc tatatgtagc tgctaaaaaa tattttacag
    31621 ctgataacaa ataaaaaaca ggagtatttt atgtgaaaaa agtatataaa aaatgcttat
    31681 gaatcagcta tatcacctta accatttgtt aatgagatgg gagaaaacat taaccacgat
    31741 tctaacgcaa acatcaagca cataaaacat ttaacactcc tcctttctgg ctgaagattt
    31801 caaccaaaca ggaagacagc gtatcaatta tagcatacac tttttcttaa attcattttt
    31861 catatgacaa aatatttcct tctaatcgac aaagttagaa ggatttttta ttgtctaaat
    31921 acacaaataa ccttaatttt taaagagcat aaggaaacgt gatatcactt tctcacgaaa
    31981 ggtgttaggt aggctgtgcc taccacgttt ctaagaaaga taaatgatat caaaattttg
    32041 gatttgtgtg tagatttgtg ggtaggatga aagcgaatgt gggcagtaaa ataagcgttt
    32101 gtgtgtagca aaatcaaaaa atgtgtaggg atatgtgtag ctacacatat ccctacacat
    32161 aataaatttg gaggaaaata tggacttatt aattagaaat attgaagaaa agtatattaa
    32221 taaaattgac aaacgttgtg aagaacttac ggtcaagact ggcaaaaaat ggagtcgaaa
    32281 tcaataccta aaagttttga tcgaaaatga ttttgatcac gctcttctga attataaaaa
    32341 agaccaattt gatcggttgt tagaaaaatt tgtggatatt caaacttata atacgaaaac
    32401 tttagaagaa tatattgcaa caaataatca attaattggt ttgttaattg aataataaaa
    32461 atagtattgt gaatttataa aaggaggaaa tcaattttgg caaaagcaac aagaaaacat
    32521 gtatatcttt acgatatgca tatcgaagta cttgatgaaa taatttctac tcatgaagat
    32581 atatctaatt atagtgaagc agtcagacat ttgtgtatga tgtatgatcc aaaaatcgaa
    32641 gaaaaaataa atccaattca aattaaattg aatgcaatgg gaaaagaaat ttctatttta
    32701 accgaaatgg tttcagagtt tgcggatctt catttgaaag atacaggaat actaattggt
    32761 acaaattcaa ctgtttatca agaagcagaa gaacgtgtgg aaggaaaaat taaatccaat
    32821 caaaccaaaa aatattcttc taagttaaag aaaccagtga atgaatctgt tcataccaga
    32881 gtagatccat ttgatccaac gaagattcta aaaagataaa agtagaagga gaacgtgatg
    32941 aataaatcgc ctgcagttat tcttacttgt caatttacct tgcccaataa aaaatctttt
    33001 tcaacataca ttgattatat gacaagagaa aaagcactgg aagaaatgga acgacgtacg
    33061 cccgaagaag aacaggaact gcaacgaatc aagaatgctt tagaggattt ttatattcct
    33121 gaaggagaaa ctttttcgga aagtaagacg gataaagaat tcagtgaaac gtcgaatgaa
    33181 gctcaatcgt tgatggaaca tggaatcaat tttgacaagt tagaggaaca agattttacc
    33241 aaatatcttt cttatatgac ccgtcactat gcgttagaac aaaagaaaga actgacgcaa
    33301 agggaacaaa aagaatacca acggttgaac caagcaatga aaaaatatca aacagagcca
    33361 cataaaaaag cttcaggaaa tcttcctgga gttttttcta tggcttcaga cgaagtgaaa
    33421 ggaagtgatc tgaaggagat caaacaaatc ttccaaagag gacaacaaaa aggctcaatc
    33481 atttatcaag atgttatctc tcacgacaat tcgtatcttg aaaaaatggg cttgtacgat
    33541 cccaaaacag ataccttaga tgaagaaggt ttgaaagcag ctggaagaaa aatgatggag
    33601 acattattcg agaaagaaca attgaatgaa acaggttact ggatggcaac gattcaccgt
    33661 aacactaagc atatccatat tcattttgca gttgttgaaa aagaaaatac gcgtaaaccg
    33721 tatactgaga ttgaaaatgg tgtgagttat atcgtaccga aggggaagag aagacaagca
    33781 acattagacg caatgaaaac caattatgta catgagttag aacgtttctc ttatgaaaag
    33841 gatcgaatga tcggtatgga gaaacgaaat ttattgacac gaaaaagtga tttgcgtaac
    33901 accttaacaa aagtagtaaa agaaccagca cgttacgatc gacacgccat gaacttatta
    33961 aatgaagtat ataaaaccct acctgaaaaa cgttcggaat ggaattatgg agatgaaaat
    34021 cgaaccaagc tttcaccatt tacaagggga aaacttgatg agttaaccaa atatgtttta
    34081 acaaaagaac ctggatatca agaatatata cagatttcaa aagcattgaa agaagaagcc
    34141 aaaagccttt atggggaaag caaaagagaa acaaagaatg cagaaaaaaa cgccctcttt
    34201 gatttaaaaa agcgcacagg aaatgcgatt ttaacagaac tgaagagaca ggatagtcaa
    34261 ataaaaccat taatagaaag tgtcaatcag atgcaatcta tttacaatga acgatccttt
    34321 cgaacactca aacagttgcc aacaaatgaa tacaagtata gttatcaaga attcgtaaag
    34381 cgtaggaaac aattccaaca aagagttgtc acgcagcgaa gcttgcgtca attaaatcga
    34441 acaattaatg cacatgaaga aaaataccac gcaagtaaag catatgaaga gcaacagcga
    34501 agaatccaaa tggaacaaga aagacaatag gaggaagaga aatgaaacaa tatttagatc
    34561 aatggaaagt catagaagga tcactaaaag aagaacgaat cgaacaactt cctgattgtt
    34621 tagaaaaaga gcatttgttt cagataagcg aaatgttgag aaacgaacag tttgatccaa
    34681 atcaattttt agttgttgag tacccagcta ctggtgtgta ttgttgtaat catgtgaagg
    34741 gtgaaaaata ttttattatt caagaatacg aaggtaagtt agcgccttat tatactactt
    34801 gggaaataaa tgaagaggga atcaataatt tcccatgtga aagcattgaa gagtctattt
    34861 ctctcacgga atgttaaata aatagagacg taaaagagtc ctgaacgtga ttgtccagga
    34921 ctctttttca atgaattgtt ttccgccaat tcactgagtg gtgcgattca attttattat
    34981 atcaaaagaa agtgagattc caaagtgaag ggaggaagaa gaaatgactc agacaacgat
    35041 tggtgttgtg gttgaaaaaa gcagggataa tctcgttttt gtgacagaaa ttcaaacagg
    35101 tagagctttt gtagtcacag acaaagctgc aaaagcgtat caaaatggca atattttaac
    35161 gttaaatctg actacgaaga tgttcgttga tgcagtagaa aattatccat ttgtttagac
    35221 aaacgatatt ttacaaggag gaaacggaca tggcagaaga aaaagaacca ctagataata
    35281 gtcgtttggg aaagtccaaa agaaaattag tacggttgca aaacgaatta aataatcaat
    35341 ttcaaaagct atttgatcac caaaaattga caaatgggca accaatgaat gacaaacgaa
    35401 atggtcgttc atggtttaac cagcaagaaa aaatagaaaa taaaatacaa agtttgagag
    35461 aagagatcaa gcaacaagaa aaacaggtag aaaaacttga aagacaagaa gagctaaagg
    35521 aaatgggtta taacaagtac ggtggcctgg acatgacgat cgaaaatatt ccaagaatca
    35581 aagaagaaat cgaacgcttt gaaaaaggtg aatcgacttt ttcagctgcc acgatccgaa
    35641 aataccaacg aaaattggaa acattagaac agctgaaaga aaaatcagag aaaggaaaag
    35701 aaaatcttct tcctgaagta caagcgatca ttgacagcgg acgagtgacg caatggaaaa
    35761 agaatccaac tatctatttt ctgaaaggct atcgaaaagt cgctttagaa ctcaatgaaa
    35821 acgggggatt tgaggaatct aaaaaatacc aagccacgtc ggaagaagaa aaggcagctg
    35881 ttcgtgaatt acttgaagaa gctacaccta ctgattctgt gaaggagaaa gaaaccgatc
    35941 atttctatcg agtagaattc aacgaaaatg atccagcaaa agggttgaaa agttatggtg
    36001 gggagatcgt aacactagaa ttgatcgatc aactcaaaac actggataac caatacgccg
    36061 cagaagcagg ctattataaa ttctattttg aagaagtgaa gaatggagaa gtagtcgatc
    36121 agatacgaat ggatctaggg gatggcgtca atagtaatca ccccatctat ttagagttag
    36181 ctagattgtg cgaacaatca cctgaaaagg aacaagaaca aacagtcaaa aatgaaccta
    36241 tttcaaaagt acaaaacgag attaaagaga caaaaacaaa acaaaagggt tatcaaaaac
    36301 gaacggcaga agagattaag caagaagtca aatcactttc ccaacaggcg cttgatgcgg
    36361 tgaaaaagca tactcattca cctgaagacg tcaaagaact tttgaatttt atgtctcgtt
    36421 ttccagaacg atcctttaga aatcaattat tgatcgagga acaatttcca ggcgcaacgg
    36481 cttgtttagg tcgtgccgcg ttgaaaaaag aaggaatcta tatcaaaaaa ggagaacaag
    36541 ggaacaagat ctttgtcaga aaaacggtca aaggatttta tgagaaagga cgtggctttg
    36601 ttcgagaaac agaggctaca ccagaagata aaaaacgaat cgaaagtggt caaatcgaag
    36661 tgatcaaaaa accttactac acgattgaaa aagtgtttga tatcacacaa acacaattga
    36721 aacctgaaga ctatccgaaa atcttcccga accgcgtctt tgattttcaa ttggatcaaa
    36781 cagggcagac agaacttcaa gttgggattc aagcggtagc caaaaatatt ggaattcaaa
    36841 ttcgagatat gacagaaagt gaagtctatc aaagagaatt aggacaagca cgtggggcgt
    36901 acgttcgtaa cgaatttact ggcgaagaag aaatcgtcat gaatactcga aatactccta
    36961 cgcagcattt agccacaagt attcacgaat tagcccatgc tagaatgcac aaattttcag
    37021 aattagatac tgcaacaaaa gaactacagg cagaaatgac ctcctatatt gtgtgcaagc
    37081 attttgggat ggacacctcg gagaaagcta ttccttatat tgcgacatgg acgaagaata
    37141 gtcagacgtt ggatgataag gaagctgcgg aacgtgggaa aatcatgaat gatgtcagtc
    37201 gtgtcgcaaa tgaattcatt caaaccattt ctaatgaaat caatcaatac agagaaagag
    37261 aaccagagat ccagccagca gaagtgaagc aggagcataa aaatactgta gaaacggcag
    37321 aacaaaagaa tattgtgccc gttggctcac tttggatcga caagaaagac gggaaagtcc
    37381 tggaagaaga cacgggccga acgttacatt tgaaggatgc ggcgtttatt gaagatccgc
    37441 agcataatca agtgatttta aaaggaaaaa gttatggaaa agagatccaa acggcgttac
    37501 cttcagaaga atttgcgcta ggaaatccat tccgattttc acttgagaca gtgtcagaag
    37561 tggcaaaacg aaaaaatgaa atctattatg aacaacaatt gtcacaaaaa gaacgcgtat
    37621 aaaacaagca agaaagacta tctgaaaaat ggatagtctt ttttcttttg ggaggtttga
    37681 aaatgacaga gaaaaaaatg agtctcattg atcgatgcaa gcaaatggat attgtggatt
    37741 ttgcacgaaa caatggttta gcggtggcca ataaaggacg agactatcgc ttagaagacc
    37801 atgattcatt tgtttttgat cgaagaaaac aacgttttta ttggaacagt caaaatatta
    37861 gtggcgacat tattgaatta gctaaacttt ttttcataga caaagagatc caagacccta
    37921 agcaacaatt taaagcagcc actgatttta ttctaaagaa tgaagacaaa acagaacgag
    37981 tggaaaatct tcattttgag acagaaaagt acaaagatca ccccgttgat tatcaaccac
    38041 tcacagaaaa aggaaggaat ta
//
LOCUS       DAXQKX010000022        36567 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.022, whole genome shotgun sequence.
ACCESSION   DAXQKX010000022 DAXQKX010000000
VERSION     DAXQKX010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36567)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36567)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36567
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.022"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(25..1521)
                     /gene="lysS"
                     /locus_tag="ACF3MF_001255"
     CDS             complement(25..1521)
                     /gene="lysS"
                     /locus_tag="ACF3MF_001255"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HFE3927260.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1632..2636)
                     /gene="dusB"
                     /locus_tag="ACF3MF_001256"
     CDS             complement(1632..2636)
                     /gene="dusB"
                     /locus_tag="ACF3MF_001256"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HFE3927261.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2637..3524)
                     /gene="hslO"
                     /locus_tag="ACF3MF_001257"
     CDS             complement(2637..3524)
                     /gene="hslO"
                     /locus_tag="ACF3MF_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HFE3927262.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3741..5852)
                     /gene="ftsH"
                     /locus_tag="ACF3MF_001258"
     CDS             complement(3741..5852)
                     /gene="ftsH"
                     /locus_tag="ACF3MF_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HFE3927263.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5942..6487)
                     /gene="hpt"
                     /locus_tag="ACF3MF_001259"
     CDS             complement(5942..6487)
                     /gene="hpt"
                     /locus_tag="ACF3MF_001259"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HFE3927264.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6487..7932)
                     /gene="tilS"
                     /locus_tag="ACF3MF_001260"
     CDS             complement(6487..7932)
                     /gene="tilS"
                     /locus_tag="ACF3MF_001260"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HFE3927265.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8052..8522)
                     /locus_tag="ACF3MF_001261"
     CDS             complement(8052..8522)
                     /locus_tag="ACF3MF_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1 domain-containing RNA-binding protein"
                     /protein_id="HFE3927266.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8568..8993)
                     /locus_tag="ACF3MF_001262"
     CDS             complement(8568..8993)
                     /locus_tag="ACF3MF_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HFE3927267.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9060..9329)
                     /locus_tag="ACF3MF_001263"
     CDS             complement(9060..9329)
                     /locus_tag="ACF3MF_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HFE3927268.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9340..10935)
                     /locus_tag="ACF3MF_001264"
     CDS             complement(9340..10935)
                     /locus_tag="ACF3MF_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFE3927269.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10950..14471)
                     /gene="mfd"
                     /locus_tag="ACF3MF_001265"
     CDS             complement(10950..14471)
                     /gene="mfd"
                     /locus_tag="ACF3MF_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HFE3927270.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14488..15048)
                     /gene="pth"
                     /locus_tag="ACF3MF_001266"
     CDS             complement(14488..15048)
                     /gene="pth"
                     /locus_tag="ACF3MF_001266"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HFE3927271.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15401..16375
                     /locus_tag="ACF3MF_001267"
     CDS             15401..16375
                     /locus_tag="ACF3MF_001267"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFE3927272.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16545..17945
                     /locus_tag="ACF3MF_001268"
     CDS             16545..17945
                     /locus_tag="ACF3MF_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HFE3927273.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18023..18745)
                     /locus_tag="ACF3MF_001269"
     CDS             complement(18023..18745)
                     /locus_tag="ACF3MF_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFE3927274.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18824..19330)
                     /locus_tag="ACF3MF_001270"
     CDS             complement(18824..19330)
                     /locus_tag="ACF3MF_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFE3927275.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19453..21252
                     /locus_tag="ACF3MF_001271"
     CDS             19453..21252
                     /locus_tag="ACF3MF_001271"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HFE3927276.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21320..22894)
                     /locus_tag="ACF3MF_001272"
     CDS             complement(21320..22894)
                     /locus_tag="ACF3MF_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NlpC/P60 family protein"
                     /protein_id="HFE3927277.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23149..23658)
                     /gene="mreD"
                     /locus_tag="ACF3MF_001273"
     CDS             complement(23149..23658)
                     /gene="mreD"
                     /locus_tag="ACF3MF_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HFE3927278.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23662..24516)
                     /gene="mreC"
                     /locus_tag="ACF3MF_001274"
     CDS             complement(23662..24516)
                     /gene="mreC"
                     /locus_tag="ACF3MF_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HFE3927279.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24671..25309)
                     /locus_tag="ACF3MF_001275"
     CDS             complement(24671..25309)
                     /locus_tag="ACF3MF_001275"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HFE3927280.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25310..25960)
                     /gene="rpe"
                     /locus_tag="ACF3MF_001276"
     CDS             complement(25310..25960)
                     /gene="rpe"
                     /locus_tag="ACF3MF_001276"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFE3927281.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(25973..26872)
                     /gene="rsgA"
                     /locus_tag="ACF3MF_001277"
     CDS             complement(25973..26872)
                     /gene="rsgA"
                     /locus_tag="ACF3MF_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HFE3927282.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27037..29106)
                     /gene="pknB"
                     /locus_tag="ACF3MF_001278"
     CDS             complement(27037..29106)
                     /gene="pknB"
                     /locus_tag="ACF3MF_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HFE3927283.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29103..29843)
                     /locus_tag="ACF3MF_001279"
     CDS             complement(29103..29843)
                     /locus_tag="ACF3MF_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HFE3927284.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(29856..31214)
                     /gene="rsmB"
                     /locus_tag="ACF3MF_001280"
     CDS             complement(29856..31214)
                     /gene="rsmB"
                     /locus_tag="ACF3MF_001280"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HFE3927285.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31214..32152)
                     /gene="fmt"
                     /locus_tag="ACF3MF_001281"
     CDS             complement(31214..32152)
                     /gene="fmt"
                     /locus_tag="ACF3MF_001281"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HFE3927286.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32145..32636)
                     /gene="def"
                     /locus_tag="ACF3MF_001282"
     CDS             complement(32145..32636)
                     /gene="def"
                     /locus_tag="ACF3MF_001282"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFE3927287.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32651..35059)
                     /gene="priA"
                     /locus_tag="ACF3MF_001283"
     CDS             complement(32651..35059)
                     /gene="priA"
                     /locus_tag="ACF3MF_001283"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HFE3927288.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35312..35617)
                     /gene="rpoZ"
                     /locus_tag="ACF3MF_001284"
     CDS             complement(35312..35617)
                     /gene="rpoZ"
                     /locus_tag="ACF3MF_001284"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFE3927289.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35622..36236)
                     /gene="gmk"
                     /locus_tag="ACF3MF_001285"
     CDS             complement(35622..36236)
                     /gene="gmk"
                     /locus_tag="ACF3MF_001285"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFE3927290.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYINKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
BASE COUNT         9885 a         7988 c         6706 g        11988 t
ORIGIN      
        1 attccttaga cagcttttat tcgattatct cattgttggg aatagcaaaa catcccgaat
       61 tgattgtgca tcagttagca acattactaa tctgtcgatc ccgatgccta gaccaccagt
      121 tggcggcata ccgtattcta aggcttccaa gaagtcttcg tctacaccgt gagcttcgtc
      181 atttcctagt tcacgttctt tttcttgcgc ttcgaatctt tctctttgat caattggatc
      241 gttcagttct gtaaaggcat tagcaaattc gcgccccact atgaatagtt cgaatcgatc
      301 tgtgaatcga ggatcttctg gatttttctt cgctaaaggc gaaacttcga ctggatgtcc
      361 gtatacaaac gtcggttgtg tcaatgtttc ttcaacaaat gtttcaaaga attcattgat
      421 aacatgtccg acacccatag cttcggttac ttctacattg tgtttttcgg ctaaagctaa
      481 tgcttcttcc aatgtcattt cttgccagaa gtctacacca gtttgttctt tgattgcatc
      541 taccatatgg atgcgtttaa agtcactttc taagtcgaca gcttgtccat catatgtgat
      601 ttttgctgtt cctagtactt tttcagctgc gttacggata ataccttctg tcagattcat
      661 tacatcattg aaatcagtat atgctgtgta tgcttctaac atcgtaaatt ctggattatg
      721 tgtagtatca attccttcat tacggaaaac gcggccgatt tcataaactt tttccattcc
      781 gccaacaatt agtcgtttta aatgaagttc tagcgcaata cgcaaatata aatcaatgtc
      841 cagtgcatta tgatgcgtga taaatgggcg tgcggcagct ccacctgcct cattgtgcaa
      901 tactggtgtt tctacttcaa tatagccatt gccatctaaa tagcgacgga tttcgctgat
      961 aatttggctt cgtttcataa atcggtcaaa gctttcgcga ttactgatta aatccaagta
     1021 gcgttgtctg tagcgttgtt caatattcgt taagccatgg tatttatctg gcagtggacg
     1081 aagtgctttt gacaaaatcg tgatttctga agctttgata gaaacttcgc ctgtgtctgt
     1141 tttcatgatt tgtccagtta caccaaagaa atctccaagg tctgcatgtt tgaatacttc
     1201 ataggcctca tcacctactt ggtcttttct tacataaatt tgaatttggc cttcacgatc
     1261 ttgtagatgc gcaaatccag ttttcccttt tcctcggcga gtcatcatac gaccagctac
     1321 actagcggtc aatcccattt ctgctagttc ttcttttgtt cttggatcaa atagttcatg
     1381 caattcttct gagttgtgcg tgcgttcaaa tcgttttcca aatggatcga ttccatcttc
     1441 acgcaattgt tccatttttt gacgacgtac aagcatttga tcatttaaat cttctacttg
     1501 atgttgttgt tcctgtgtca caaaagttcc tccattctca tgttaatctc tttcctataa
     1561 tgccaatgaa acacaaaaaa agcaagccga acttggaatt tcggcttgaa aattcacgaa
     1621 aaacttagaa atcacaacgt ttgtttcaat agtacttttt ccgctttttc tacaaattga
     1681 tccagcaggt cattgatttc ttgctgtttt tctgtctgat tgattgctac tttcactttc
     1741 gctgctcgag gaatcccttt taaataataa gccgcatgtg ttctgaattc tctacaagct
     1801 actttttctc ctttgagatc tgctaagcgt tgtaaatgaa gtttagctgt agcaattttt
     1861 tcggctggtg ttggttcagg aatcagttct cctgtttcga gataatgctg tgtgcggtga
     1921 atcatccatg gattgcccag cgctgcacga ccaatcatca caccgtctgc accgacatag
     1981 tcaagcatcc attttgcatc ttctggcgtt ttgacatccc cgttccccat aaatgggatc
     2041 gtcaaatgtt ttttcacttc tttcaatact tcccagtccg cttttccttc atacatctga
     2101 acccgtgtac gtccatgcat agcgatggca cttgctccag ctgattgtgc tgctaatgca
     2161 ttttctacag caaagacgtg ctcttcatcc caaccaatac gcatcttgat tgttactggg
     2221 atatttactg ctgaagaaac agcttggacc atttcgtata ctttctcagg atctaaaagc
     2281 cattttgctc ctgcttctgc tttgattact ttatttactg gacagcccat attgatatct
     2341 attatatcgg cagctgtgtt ttcttcgaca aattgagcag cttcaactag actatcttta
     2401 tttccgccaa atatctgtaa acttaatgga tgttctgttt cttcaatgtg gagcatctct
     2461 aaagtttttt tgtttctgaa atgaatacct tggtcactga tcatttcaca tacgactaag
     2521 cccgcaccaa attctttgac agtgactcga aatgctgaat ttgttattcc agccatcggt
     2581 gcaacaacga cacgattagg gatttccaca ttgccaattt tccatgtgtg ttccacttaa
     2641 atccctccta aggcttcttt cttcaatcca tctaattctt cttcgctata cttgtatttg
     2701 ttattacaga aagaacaaac cgcttctgca ccgtgatctt cgtctatcat tgcttggatt
     2761 tcttctgcac ctaacgcgat aattgcttct gcaaattttt cttttgaaca gtcacatttg
     2821 aattgaacag gcattttttc caaaatgttc aattcttctg taccaagcaa tcctttcaat
     2881 atttcttctg gtgtctgtcc ttcatctaag agggtagaga ttcttggtgt cgtttttaat
     2941 tgttcttcga tcttgctgat tgtttcttca tcggcacctg gcatgatttg gatcatgaat
     3001 cctcccgccg tcttgatgct gtcgtcagta ttgaccaata cactcagtcc aacagctgaa
     3061 gggatttgtt ctgagatagc aagatagtaa gtaaaatctt cagcgatttc tccagaaaca
     3121 atcggcgttt gcccagaaaa aggttctttt aatcctaagt cttttgtgac agtaaacatt
     3181 ccttgtgttc caactgctcc ccgcacatcg attttacctt cactatttag aggaagactg
     3241 agatgcggat ttttgatgta acctttcaca tctccctttc catttgcatc tactacaatt
     3301 cctgttgctg gaccatcgcc ttggattcga acagttagtt tgtcttctcc tttgagcgtc
     3361 gcaccaagta gcagactacc gaccaatgtc cgtcccaaag cagctgagga ggtgtgccaa
     3421 gtatcatgac gtctttgtgc ctccgctacg gtatttgttg cttgaacggc gtatgctcgg
     3481 acgaatccgt cgtgagcaag tgccttaacc aaataatctt tcatttgtta tgtactcctt
     3541 tttccgtttt taaactcata gtgaatcata ctagcaacta ctgctttttt caactttgga
     3601 atgcttcttt taaaaataat tcagaatcat ctagaaaaca ggacatcacc ctatttacaa
     3661 cttaaataaa gaaatctccc gaaaaccggt ttttgttccg gttttcggga gtcatatcag
     3721 atcaattgac ctatattttt ttatttgtat tgatcgtctg aatgattatc ttctgattgt
     3781 tgagaatctg aatcatgttc tgctttattt tcctcattca gttcatgttt tgcttcttca
     3841 aaatcacgtt tttcttccgc ttgtttttca gcgtcttttt cttccaaagc acgttttgct
     3901 tcttcaaaag ttttcgcttc tttttcgctt ggataatcat ttgactcagt accttcaggc
     3961 atcacaccgt gttcaaacaa tgacttgatt gctttggcat ccaatgtttc gaattccaaa
     4021 agtttttcag caatcagttt atgctgtgca cgatgagctt cgatgatttc tcgagcttta
     4081 tcatgagctt ccatcaagat ttttcgtact tcttgatcaa tctcgaaagc gacttgttcc
     4141 gagtaagctt ttgtttgacc atagtcgcgg ccaacaaaca cttgatggtt tccttcatat
     4201 tgaacaggac ctaaacgatc actcattcca tattctgtta ccatgcttcg tgctagagct
     4261 gtcgcttgct caaagtcatt ggaagcacca gttgattgga cattgaagat gatttcttca
     4321 gctgtacgtc caccaagtaa gcctacgatt tgttcaaaca tatcttcttt cgtcatcaag
     4381 aactgatctt cttttggtaa agcgatcata tatccgccgg cgcgtccgcg agggatgatc
     4441 gttactttgt ggacgacccg agcgcgactc aatactaatc cgacaatcgt atgaccagct
     4501 tcgtgataag caaccatttc gcgttctttt ttgctgatta cgcgatcttt tttagctgga
     4561 cctgcaatca cgcgatcttc cgcttcatcg atatcagaag catcgatttt ctttttattt
     4621 cttctagcag ctactaacgc tgcttcattc aagacatttt ctaaatctgc tccggcaaaa
     4681 cctggtgtct gttgagccac aactttcaag tcaacgtcat ctgccatcgg tttattccgt
     4741 gcatggactc gcaagattgc ttcacgacct tttacatctg gacgtccaac taaaatctgg
     4801 cggtcaaaac ggcctggacg tagtaacgct gggtctagta catcagaacg gttggttgca
     4861 gcaatgacga ttactccttc atttccgtcg aagccatcca tttctacaag caattggttc
     4921 aatgtttgtt cgcgttcatc atgtccgccg cccataccgg caccacgttg acgacctacc
     4981 gcatcaattt catcaatgaa aatgatagct ggtgcgtttt tcttcgctgt ttcaaacaaa
     5041 tcacgaacac gacttgctcc aacaccgaca aacatttcta cgaaatcaga acccgagatc
     5101 gagtaaaacg gtactccagc ttctccggca acagcttttg ctaataaggt tttacctgtt
     5161 cctggaggtc cttctaaaag tacacctgcc gggatacggg cacctaattc aacaaatcgg
     5221 cgaggatctt tcagaaattc aacaacttca actagttctt gtttttcttc ttccgcaccc
     5281 gctacatcag aaaaacgtac gcgattagct tttttgtctg cttctttggc ttttgattta
     5341 ccaaagttca tgacacggcc gccaccgcca ccgccgccgc cttgttgtcc catcatcatg
     5401 taaaagaaaa agatgatgat tacgattggc aagaagctaa gcaataggga aacccatata
     5461 ccgctgcttg attcttcttt tactgttgta gcaactttgt tttcttttgc cagttctgtt
     5521 acttggctca atgttgtatc atttggcaaa atgattgttg tgaaatgggt agtagtcgta
     5581 tctgttgaac ctaagatagc taacccaccg ctgttagcga cggtctgctg ttctttgtat
     5641 tcaccagtga tcttatatac accatttgca ggctgcactt caaattcttt gatcttgcct
     5701 gcttgtagtt gttctgtgaa ttttgagtac tcgatatctg acgatcgctg gccgttatta
     5761 ccaaaaatga aataaacgac cattaccatc gctaagatta cgaggacata atacaaggca
     5821 tttttcatca tgccgttgtt ctttttgttc atagttgccc tccctaagcg tcaatttaat
     5881 ttaacagttt tttatcaatc ctgaccattc tattgtacca taatttaatt gagatacagc
     5941 attaatttga ttgataaaca ctaggtttca atacaccgat gtacggaagg ttacgatatg
     6001 cttctgcata atccaagcca taaccgacca caaattcatt tggtacgttg aagccaacat
     6061 aatctgcttc gatatttact actcttcctt caggtttgtc aagtagtgta acaattttga
     6121 ctgattttgc tttgcggtat ttgaaaagat ccactaaata agcaagtgtt cttccgctgt
     6181 caatgatatc ttcaacgatc aacagatcgc gaccttctac attcgtatct aagtctttga
     6241 cgatttttac ttcccctgac gagactgttg cattcccgta gcttgaaaca tccatgaaat
     6301 ccaattccaa atacgtatcg atagaacgaa cgatatctgc catgaatggt accgctcctt
     6361 ttaagacacc tactactagg ggattggtgt tttggtaaat ttctgttaac tctttgccta
     6421 gttctttgca acgaacttgt atctcttctt gtgagatcaa aattctctca atatcctttt
     6481 ccaacatcag gttctccttc caattgcttc tttttgatat ttgtaaagaa gtatgtagtg
     6541 tattttatca gtttcttcac gaatactcaa atatgaaaag gcaaaaggta tcaagctata
     6601 tatatttctt ttggcatctg taatgatcca agcatgctgc ctttgtgaat taggtacttt
     6661 ctgatcgata aaatatctag atactttttt tgtgagattc tctgttaatt taatgcggtc
     6721 tcctgctttt cttttttcga catacagttg cacatcagca ggaatccaaa tgtcatgaga
     6781 aaatagagac catgaatctg ttgctttgat gtcccctgca ttttcaggtt tgaccagacc
     6841 aatccattct gtttcattca aatatattcc ttgttctgga atcagcaaca agcgctggtc
     6901 ttctgtctgg ctagttgctt gtttttcttt tttagagagt acaacaaaat gatactctct
     6961 tttcagtatc caattattgc caatactgag ttgccattgg ctttttttct gttgccactg
     7021 gtctaaaatc gactccattt gttgttcttt caaaataatt cctgtttttg agaatgcttt
     7081 gtcgaaaaag gagtaaaaaa aatagtatcg ttcagcatct gtcatttctt caatcatttc
     7141 tgcagaaaat cgaaattgtt cctcccactg ttcgacttcc ttttcgatca actgtcccat
     7201 atatttttga atgacttggt ctgcccattg gatctgttgc gaaaattgct ggaaatgtct
     7261 caacgcctgt gtattttctt gtttcaattg aggaactacc aaatgacgaa gccgatttct
     7321 ctggatatct aacaattggt ttgtctgatc ctcaaagtaa acaagctgcg attccgctgc
     7381 ataagtatat aggtcttctt tgctaaaact cagcaacgga cgaatcagtc tgcccgtagc
     7441 aaatggttgt acttctttga ttccagaaaa agtatttaac tgtcccccac gaacgatttt
     7501 cattaacacc gtctcgattt gatcatctcc gtgatgagca gtcatcaacg tgtcatattg
     7561 tccttcttcc atcacgcgag tgaattcttg ataacgaaag ttacgagctt ctgtttctat
     7621 ggcggatttg gctggatctt cccaaatact tacatataaa gggagattct tctcttcaca
     7681 atatgagcga agataggcag cttcttctgc tgattcttct cttaattggt gattgatgtg
     7741 gacgatacct aaagaaaaac cgatttggcg ttgcacttgt aaaagtaaat ggagcaaaac
     7801 catcgaatca acaccacctg ataccgctgc taaaattctc gatccttgtt gccagaatcc
     7861 ttgttcattc ccgtgccgaa taaatgactg ctgtaatagc ggtgcttttt tcccgccttt
     7921 ttcaacgttc atcctttcca caccctttct tcctaaaaaa aagagagcgg gaaaacgtct
     7981 aaaacgacaa ttaacctgcc ctctgttgat actatgaccc aaatagtcgc actatcatta
     8041 tttgcggctt tttagctgcg acgtccgcca cggccaccgc gctttccttc tgtgtttcgc
     8101 ttcaatgaag ataagcggtc atcgctatct ttcaaaaatg aactcatcaa tgaatcgaag
     8161 tcttcttttt gagctgaagg ttgactgcga gaaaaagatt ttttctgtgc tggacgattt
     8221 cggttgtcac ggggatcttt ttgttgatat tttttaggac ggctttcttc tccagattca
     8281 gcaggttgtt cctgcgcttt ccggatagat agtccgattt ttccatcatc atttactgaa
     8341 ataactttaa ctgttacttc atctcctaca cttaaaacat catggatgtc ttttacatag
     8401 ccatttgaca cttcgctaat atgaactaga cccgtttttc cagcacctag atcaataaac
     8461 gcaccaaaat ttgtgattcc tgatactttt ccttgcagtt ttgctcctac ctcgattgac
     8521 ataaaaaaaa tgttcctcct aattatttcc cttttttata ttcctgctta ttttgcagtt
     8581 gtagaactag ttgattgatc tgtttcattt gtcgagctgt ctgtatttga ttctaatata
     8641 ggataaactt tttcaccgtc ttttgagtaa aagaatttgc ttctggcaag tttagctaca
     8701 tactcatcat ctttcagcaa tgaaacatct tggtgcagct gatcaacgtc tgcgttgact
     8761 tctttcattt cagtatttgc ttcgactctc aattcgttca attgatgcat cctttgcatg
     8821 tcatggaaaa tctgcacacc tattatcgcg aaaatgacca aagcaccaac aaaaattgca
     8881 gccagtctgc gtcttcgaaa aatcagttga cgttgttgtt gctgaaattc agcatacttt
     8941 ttctttgcat attccgtatc tagcgcagcg attttattgc tttttttcgt cacttggatt
     9001 cgctccaatc tttttgattg tctttttcat tataccaata tcgtgaaagc ttgtctaatc
     9061 tatttctcta gtgtttctgt gcgattttca gaaataattt cgtacatttt ttgtgcatct
     9121 tcttttttgg ttgattcatg taattccgta attttcactt ccaacgtttt gttgccaaac
     9181 tggactttca aaatatcgcc tactttgaca tcactggaag atttcgccaa tttaccgttg
     9241 atttgaattc ttcctttatc agctacttct tttgctactg atcgtctttt gatgattcgg
     9301 gaaattttta aaaatttatc taatcgcata tcttattcct cactttttaa tttttttatt
     9361 taatcgcagg attttcttac caaaaggcaa cattagccat tctcgtactg taaacagacg
     9421 aagacgaatc actgcataaa tgaacacaga agccccgatc ccaactccta tcacgctgac
     9481 aaaaaaagca gtggaacgat gagttacagg accaaatact atattcaata caccataata
     9541 cagcagcagt actactgtca tacaaagaag gctgaacatc aacttccgtc caaaatgccg
     9601 ttctttccaa aaagcattta gctcttttgt ttcaattcga acaaaatacc aaagcgtcac
     9661 acctaatcct aaaagggtag acaggcttgc acctgctgtt cctaataaac cggtcagaaa
     9721 agaagtagtc aatcctttta ccaatagtcc ccatcctgcg ccttttaaag aagggcgaaa
     9781 cgagttcttg ctttgagcaa tactttgata agcttggatg actgcagtga aagcaatgga
     9841 aaaaacaaat aatacaagcg ctgcatttcc cgcataatct ttaaacaacg cataattgat
     9901 ataagggagc agcaaggcta atcccaaaga cgcagctaat gctaaagcgg tcgtcaatct
     9961 aagatagatt ttggctgtct gtaaaaactg acgatagatc cggttggtca aatgacgagt
    10021 caacgcaggc aggaatgtcg cacttaatgc agtggcaatc actaaaccta attgtactaa
    10081 aggctgacct cgatcataga ccccttttgc tatcttcgca ccgtattctg acagtccgta
    10141 aacttccaaa gcatttttta caaagaaaga gtcgatcagc tggaaaaaga taagcaatcc
    10201 actataaatc gaaaccagtc cgccttctac cagaaaacgc cggatcaagg gctttgacgg
    10261 ctgtttgaac aatggaaacc gtcggaagct taacgctcct ccatgaatct tttgttcata
    10321 gtagtgaagg atcccatatg cgcataaacc gccaaaaaca gctccactca ttgctgccgt
    10381 ccctgtttgg tacaccgtcc atccaagctt tctaaaagca aacgcactac agacaatcac
    10441 aaaaacacga acgaactgct caactacttg agaaacagca gttggttcca tcaagaatct
    10501 tccttggaaa ttccctcgat aaaaagatag accaggcatc agcaaaaagg taaaggaaac
    10561 tacttggatc agcggtttca attgtatgtc tcccatcatc caagcaatcc agctgctaaa
    10621 tgcaaagaca aacaaccaca aaaagacacc tgtccaaaat actaagggat aaagattttg
    10681 caaagcttgc tttcgctcga aaggattctt tctttctgca acgtactttg atatgaactg
    10741 cggaagaccg gataaagcta aagtcattgc tatcccataa attggataaa cttgctgata
    10801 aacataaaaa ccttcgtcgc cgactaagtt ttggagggga attcggtaaa gggcacttaa
    10861 tacttttgct atgaaagaag caatcgtcaa tacaaatgct ccttgcatga cgcgccgcat
    10921 ttctttatga tccaaatcat tgctccttcc tacgctgaca gatatttttg ctcacgcaac
    10981 gctttgacaa acttttggat ttcctgaagc catactgctt cttccatttg gttggggatc
    11041 gtcaagcgta tcaccatctg ttctttttca acgcctagac tggcttttag ttttgtcgct
    11101 gtcagtgctt cgaataactg ttccacacta tagcgttttg ttccaacttt acttagagta
    11161 aagactatat gcgcctcctg tttccttatc gtttctagga gcgctcgatc gccatccatt
    11221 ttgatctgcc caattgtcaa gagatgtgct acttcttctg gatattctcc aaaacggtcg
    11281 agcagatcat cttctagttc atctagcatt tcttgcgaat caagttcacg aattcgttta
    11341 tagatctcga ttttctgccg ttgatctgcc acgtatgttt caggtagata cgcatcgaca
    11401 ccgaggtcga tctcaacagt ggtcttctcc acttgactat tctttccttg tttacgagaa
    11461 acagcttcgc ttagcatttg agaatacata tcgaaaccga ctgcatcaat aaatccatgc
    11521 tgctgagcac ctaagagatt acctgcaccg cgaatggaaa gatcccgcat cgcaatcttg
    11581 aatccagatc ccagttctgt aaaatctttg attgcctgaa gacgtttttc actgacttcg
    11641 ttaaggatct tctgctgctc atacataaag taagcatatg cgacacggct gcttcttcct
    11701 acccgccctc gcaattggta taacgtggat aatcccatat aatcagcgtt ctcaacgaac
    11761 aacgtatttg cgttcgggat atctactcct gtttcaatga tggttgtagt gacaagaaca
    11821 tcatattgac cttcaataaa ttcaaaaagc gtattttcta attgcgcctc tgtcatttgc
    11881 ccatgagcat aaccgatccg tgcttccgga acgagttctt ggatttcttc tactttttgt
    11941 tcgatcgttt ctacccgatt atataaatag aatacttgtc cacctcgtcc catttctcga
    12001 tggattgctt cgcgaatagc cccaggattt ttttccataa catacgtttg gatcggataa
    12061 cgattcgcag gcggtgtttc gattactgaa agatcccgca cgcctaacat cgacatatgc
    12121 aaagttctcg gaatcggtgt tgcagtcaga gtcaaaacat ccacttgtgc acgtaactgt
    12181 ttcaatcgtt ccttatgttt tacaccaaaa cgttgttctt cgtcaatgat cagtagaccc
    12241 aaatcgctaa attcaatatc ttttgacaaa attcggtggg ttcctacaac aatatcaact
    12301 tgacctgtac gcagttgttc gatggtttct ttttgttgct ttcttgttct gaaacgactt
    12361 aatagcccga tatttacggg gaaaccttca aatctttcca gcatcgtttc atagtgctgc
    12421 tgtgccaaga tcgttgttgg aactaaaaag gctacttgtt tgctttcctt tatcgcttta
    12481 aaggccgctc gaagcgctac ttctgttttc ccataaccaa catcacctac gagtagtcga
    12541 tccattggtt tttctttttc catatcccgt ttgatctccg ctgcacttct caactggtca
    12601 tcagtttcag agtaggggaa ggcattttcg aattcttttt ggtaggcgtc atcaggtcca
    12661 aaagcatatc ctttttctga ctctcttgcg gcatataatt tgattagatc gtcagcgata
    12721 tcctcgattt ttgaagagac ttttcgcttg gttttcgtcc attcacttcc gcctagctta
    12781 ttgatgcgag gcgctttggc ttcagaggcg acatattttt ggatcagatt cagttgagta
    12841 acaggaataa acagtttgtc gtcgttttga tacaaaatag tcatatagtc ttggtgaacg
    12901 ccatctactt ctagcgtttc catcccaatg tatttcccga taccatgatt ggcatggaca
    12961 acgtaatctc ctgcttttaa ctcattatag cttttcaatc gctctgcgtt tgttactgtt
    13021 tgacgtctcg tttgtttttt cgtcgttttt tggaaaattt ctttttctgt gatagctact
    13081 attttttctt gaggaagttc aaaaccagcc tgcaaagctc cttcaactaa ttgtacctgt
    13141 cctctgatca atgcattttt ttctgtttct actactaata tgtcttcatc tcgaagcatt
    13201 tgttctgctt tgcgtattct gtcctttgtc ggaataaaga tcacaacagt ctgtttttgc
    13261 ttgcgccaac ggtccatttc tgttttcagc aatggcattt gtccgaagaa ctgttgcatc
    13321 gtccgatatt gaaaattatg gattgcttgg aaacgaagat ttcccatccc tttttggaag
    13381 agtgagaaaa aggttgtggt gaacttttcc ttctgcacga ttttttgtat atctgctgaa
    13441 aatgtctgct cagaaaacac ccgcaattcg ctgatttttt gagtctgcca ttctgccgct
    13501 tccctttcga tttcccgatt tgtttccatg attcgctgat aatcatcaac gactagtaaa
    13561 ctatttgaag ggaaataatc caagatcgtc acagattctt ggtaaagaag atctgagtag
    13621 aattttgctt cttctgtcgg gacacctgct tgccagcttg aagtcagctg accgaagtaa
    13681 tcttgcaaaa actcgcggtc tgcttcttct gtggtcgcag caagccgttt ttctagcatt
    13741 ttttgcattt gctctattcc atgttctaga tcctctggtc cgtagacttg ttcactcgtt
    13801 ggggaaaccc agatttcttc cgttttttcg attgagcgtt gtgtttctgc ttcaaaatac
    13861 cgcatagaat ctatctctac atcaaatagt tctacacgaa caggataggt tgtcgttaac
    13921 gggtaaatat cgataatgct tcctcgaata ctgaattctc ccggttttgc gaccatctct
    13981 tctcgtacat agcccatcaa agtcaattgg cgaggaagat tttccacgtc tatctcatca
    14041 ccaatatgcc aattcaattg cgcctgtagc caagttttct tattcggcag tcgtttgtgc
    14101 aaagatgcga ctggcaacaa atagatacct gctttttttt cttgaagtgc gttaagcgtt
    14161 gcaactctct cgcctcgcgc ttctggagaa gaaaaggcca tttcagcaga aagcacttca
    14221 tccactggaa ataaatggat ctgatcttgc ggaatcacat gttgcagatc ttctgctaac
    14281 tgattcgcat aatacaaatt tggcatcaga ataatcatgt ttttatttgt tttcttaaac
    14341 gctcgagcaa atagaagtgt tttcgctgag cccgctaatc ctgtgattag ttgtctaggc
    14401 attttttctt ctaaattgct gacccattct tttacttgcg gatcttttcc gactaattga
    14461 ataatatcca ttccttttcc tccttcctca attgaatcga ttcatcgcat ccacgaacga
    14521 atgcccttct atgagatatt cgactgcttt aacagattga cacatgcttt cttctatcaa
    14581 aggctgattt tctttgctga aaggactaag cacatgctgg actactgttt ttttcccttc
    14641 tggcctgccg attcccacct tgattcgatc aaagacattc gtattcaaat gggaaataat
    14701 acttttgata ccgttatgcc cgccggcact tcccttttga cggagccgga tttttcccac
    14761 tgccagatcc aaatcatcgt agattacgac taattcctct ggataaatcc caaaataagt
    14821 cattagtggg ccgactgcac gaccagattc attcatgaat gtttgtggtt tgactaaaag
    14881 gatcttttct ccattatgaa aaaattcggc aacttctgct tcgaacggat tttttttgaa
    14941 agtagcttga tgctcgcgtg caattttatc cacgaccata aagccgatat tgtgttttgt
    15001 atattggtat ttggtacctg ggtttcctaa cccgacgatc attttcattt ttgttttcca
    15061 cctaattcta aaaagcagca caaaaggctg gactgctaat tagcggtcca gtccatcgag
    15121 cttttttctt ttttatactt gtcaatgcat agtataacac aaaacaaggc gtttcggcta
    15181 aaagagaatc gttaataaat gataaagaaa ttaaaaattt cttcaaagtt taatgaaata
    15241 attgatatat aaaaatagtg aaataacgca catgtaagct tttacatata atacaacctt
    15301 gttatctgtt atattttata gccaaatagc gtgacatggg gcttgagaaa tgttagcata
    15361 agcatgggaa aaaacaaatc aatggaagga ttgatactaa atgactgcag ctgcagaaaa
    15421 aaaagatcat caaaaagtta ttcttgttgg agacggcgcc gtaggttcta gctatgcctt
    15481 tgctctagtt actcaaaata tcgctcaaga agtaggtatt gtggatatca atactgctaa
    15541 aactgaagga gacgcaattg acttgtctca cgctttggca tttacttcac ctaaaaaaat
    15601 ctattctgct acttacgcag acgcacatga tgctgactta gttgttatta cagctggcgc
    15661 accacaaaaa ccaggtgaaa ctcgtttaga cttagtaaac aaaaacctaa aaatcaaccg
    15721 cgatgttgtc acacaaatcg ttgaatcagg atttaacggt atctttttag ttgccgctaa
    15781 cccagtagat attttgactt actcaacttg gaaattctca ggtttcccta aagaacgcgt
    15841 aatcggttca ggtacctctc ttgactcagc tcgtttccgt caagcacttg cggaattagt
    15901 tgacgttgat gcacgtaacg tccatgctta catcttaggt gaacacggag attcagaatt
    15961 cccagtttgg tcacatgcaa atgttgccgg cttgcaaatc tatgaatggg taaaaaacaa
    16021 cccagaaatc gatgaagaag ctatggttaa cctattcttt ggcgtacgtg acgctgctta
    16081 cacaattatc gagaaaaaag gcgctacttt ctatggtatc gcagtagcat tagcacgtat
    16141 cactcgtgcc atcttagatg atgaaaatgc tgttcttcct ttatcagtat tcatgaatgg
    16201 cgaatatgga ttgaacgaca tctacattgg tgcacctgct gttatcaacc gtcaaggtat
    16261 ccaaaaagta atcgaaattc ctttaagtga cagcgagcaa gaccgtatgg ctgcttctgc
    16321 taagcaatta aaagaaattc tagatgaagc ttttgctaaa ctagacgctg aataatcttt
    16381 gaacatgacg gaaaacatct attcggtgtt ttccgttttt ttattttatc acccttatgg
    16441 tttctaaatt ttttcataaa gtagagataa ccttcgtctt ttcctctaaa ttatgctatc
    16501 atgagaccgt tccaccctaa acttttactt aaggagttgt cgatatgaca agatcttcgc
    16561 atcgaaaaaa atcgaaacat gttgctttgc tttcagttct tggtgttctc ttagtgctga
    16621 tcagctttta tacctatcgc agtacatact acacaaagca ttttttgccg aatacagaaa
    16681 taaatggaat aaatgtcagc aatctaacag tcgaaaaagc aaatgaaaaa ttaaaagaag
    16741 cttattctga taaaaaactg gctattaaag aagatggaaa agtctggcag gaagtaccaa
    16801 aatccgagct cggctacaaa gatgatttca cttcggagct ttctccgatc ctaaatgaac
    16861 aaaacggatg gacttgggga atgacttatg tctcagcggc agaaaaacaa gaaatagatc
    16921 ctgtcagtca aaaccaccaa aaactagaca ctaccgttca gacattgaca actaagctga
    16981 ctgatttgaa caaagaccgg acacctacta ctgatgcaac gatcgaaaaa gcaggtgact
    17041 ctttcgttat caagcctgaa gtcaatggaa atacgatcga cgtcgatgct gcggtcaaac
    17101 aattaaaaag tgcggtaaac tctggtaaag atacaattga attgactgaa ttcaaagaaa
    17161 aaccaaaagt aacatctgaa gacagctcac tgaaagaaca actcgcatcc atgaatgcta
    17221 tcgcaaatgt aaaagctact tacagtataa acggtgagac tttccagatc ccatcaagtg
    17281 atattatgag ttggctgacc tacaatgatg gaaaagtcga tttagataca gaacaagtac
    17341 gtcaatatgt aacagattta ggcacaaagt ataacacaag tacgaatgac acaaaattta
    17401 aaagtacaaa aagaggagaa gttacggtcc cagttggcac ttacagttgg acgatccaaa
    17461 cagacagtga gacagaagca ttgaaaaaag cgattctggc aggccaagat tttactcgtt
    17521 cacccattgt gcaaggtggc acaaccgctg atcatccatt gatcgaagat acgtatatcg
    17581 aagttgatct ggagaaccag catatgtggt attacaaaga cggaaaagtg gcccttgaaa
    17641 cagatatcgt ttccggaaag ccaactacac ctacacctgc tggagtcttc tatgtttgga
    17701 ataaagaaga agatgcaact ttaaaaggaa caaatgacga tggaacacct tacgagagtc
    17761 cggtaaacta ctggatgccg attgactgga caggtgttgg tatccacgat tcagactggc
    17821 aacctgaata cggtggagac ttatggaaaa cccgcggttc acacggctgc atcaacaccc
    17881 caccaagtgt aatgaaggaa ttattcggga tggtcgaaaa aggaacgcct gtattggtct
    17941 tctaacaaaa ataatatata aaaagaaagc acccgtacga ttggtacagg tgctttcttt
    18001 ttattatcta acaatgtgct acttacattt cagcagcagt aaagacttct gaaacatcat
    18061 catcgtcttc tagcttatct actagacgtt ccaattgctc tttttgttcc tcatttaaat
    18121 caatcgtcgt ttgtggaatc atcgtcaatt ctgcttgcgc caaagtgaac tctttttcca
    18181 actcatctcg tacagcagca aaatcttctg gtgcagtata aatctcgaat acttcaggag
    18241 aagtttgcag atcttctgcc cccgcctcta atacatcctc aaacatcgtc tcttcatcaa
    18301 cagtcaaccc atcgcgttca atagcgatat atcctttgcg gtcaaacaag taactgactg
    18361 aacccgtttc tcccagtgat ccaccgtttc gagtaaaagc tactcggaca tttgtcgctg
    18421 tccgattacg gttatctgtc aatgcatgga ctaagattcc tactccaccc ggaccatatc
    18481 cttcatacgt gatttcatcg taattcgttt catctacggc actcgtagcc tttttaatcg
    18541 cccgttccac attgtcgtta ggcatatttg cagcttttgc tttgtccaca acaagccgca
    18601 aagctggatt catagatgga tcaggaccgc ctgctttagc tgccatataa atttcacgag
    18661 aaagtttctg aaagactttc cctcgttttg catcttgggc attttttctt ccttggatat
    18721 tatgccattt actatgtcct gacatgattt ttcctccctt gttcttttga gaatacactt
    18781 ctattctagt actatttcac aaaaaaacaa agccacagcc aatctataaa cgcttcttga
    18841 atgccgcaaa aagcacacat aatatcacag cagtcagagc accgatcgaa tccaacatga
    18901 catcttggaa cataggtgtt cgtccaccgg tcatcatctg atggaattcg tccaaacctg
    18961 cgtaccctgt tgctgaaagc caagcaagga tcgctgtcag ccaccaaatt tttagcttgg
    19021 ggaaaacacc taaaaacaag ctgcctccca aaataaaata ggtaccgaaa tgtgcgccct
    19081 tccttaaaaa gaactctaaa aatttggcgt agcccagatg gtcgatactc accatacttc
    19141 caccataatt aaaacgtata cccgctaatg tgtctttaaa tggctgatta ggcagccagc
    19201 tttctaatcg cgaaacttgt gattgctgtc cgtaagtttg agaagaactg taaaataaga
    19261 ttataacgac tatcagtgcg attactaaat aaatatttcc gtttttcatt tgtttttttg
    19321 aagaattcat aagtcacctc tgtattttat cttagacttt ttttgaagaa acaacaatca
    19381 ttttcataga gacttcttcc ataaaaaagt gctatactta attttgtatt acaatatgaa
    19441 gggagttttt tcatgagtta ttcattaaat tggaatctag attctatttt ttccggaggc
    19501 agtcattctg atgctttgaa ccaacggatg aagcaattgg aagaccaaat gaacgagtat
    19561 tatcaccgcg taacaaaatg gtcacctagt tctgacaatg cagagcagtt aaacgctatt
    19621 cttcaattgc aagaaacgat tacgaatggt tttacccaat gcagcagcta tattactgca
    19681 ttgctttctg ccaatgtcaa tgattcagat gcaaaggtct tatcaggcaa gctttacgca
    19741 atgctgcctc gtctgcaatc agccgaaact gtattgtcaa agaaatttgc agaaatatct
    19801 gacaatgatt ggaatcagat gctttctcaa tcttcgtttg aaacaattgc ttttcgttta
    19861 aacgagattc gtcgtgatgg ctcacaatta ttatcagaag ctgaagaaaa cattataaat
    19921 acgctttctt tagatggtct aaatgcttgg agcagtcatt atgatacgat tgtagccagc
    19981 atttcgattc ccttcgaaca agatggacaa gtagtcgaat tatctgctgg acaagccttc
    20041 aataagatga tgggcgatcc agatccaaaa gtcagagaaa cacttttcgc agcatgggaa
    20101 gaagcctgga aagaaaaggc acccctcttc acggatactt tgaatcattt agatggtttt
    20161 agactttctg actatgaact tcatggtgtc acagattttc tacaaaaacc attagagtac
    20221 aatcggttga agaaagaaac attgtctgtc atgtgggata caatccagaa aaacaaacaa
    20281 ccccttgtta attacttgac tagaaaagct aatcttttcg gtaaagaaaa aatggaatgg
    20341 caagatcaag atgcacctat tattttaggc gatttgaaag aaaaaacctt tagttttgac
    20401 gaagcagcag catttattat cgaaaacttt aacaaattca gtccaaaaat ggctaaattt
    20461 gcccaatctg cttttgaaaa gagctggatc gaagcagaag atcgtcctgg gaaacgtcct
    20521 ggtggttatt gtactgagtt accagaaaca aaagaatcaa ggatctttat gacctacagt
    20581 aattctgtta atgaggttgc gacacttgct catgaactag gacatgcttt ccatagcagc
    20641 acgatgtggg atttaccttc tttaaatcgc gaatatgcca tgaatgtcgc agaaacagca
    20701 agtacattcg cagaactgat cgtagccgat gctacattaa aagtcgcaaa aacaaaagaa
    20761 gaaaaaatca atttgctaga tacaaaactg caaaatgctt tagctatgtt catgaatatc
    20821 cattcccgat tcatttttga aaatcgattc tatgaagcac ggcaagaagg attagtctca
    20881 gaagataaga tcacagagat gatggttgag gcgcaaaaag aaggctatca aggagcttta
    20941 gctacttacc atccatattt ctgggctgca aaattgcatt tctttattga tgacgtaccg
    21001 ttttataact tcccatacac atttggctac ctctttagtt tgggcatcta tgcttacgcc
    21061 aaccaaaagg gagcaaattt tgaagaagaa tatatccatt tactacgcga tactgcctca
    21121 atgacgacgg aagatcttgc gaagaaacat ttgaatgtcg atcttaccca accagatttt
    21181 tggcaagcag gtatcgacat ggtgactgaa gatatccaaa cgttcatgga attgacagaa
    21241 gaatttatct gatttctatt ttatcacaat aaaaaaagag ttagtccaga atgggctaac
    21301 tctttttgat taatcattct tacatgctga cagcaaagtc aggggcaaac cattgaactg
    21361 aaccaacttt tacgctttcg cctggttgag gagcatggat atattgtcct ccgcctaaag
    21421 caatcgctac gtggtaagtt ccgccttgtg acccccagaa taacaagtct ccagcttttg
    21481 cttgagaaac tgaaattttt gttccagctg attcttgagg aactgtccaa ccaccgatgt
    21541 cacgaccagt tacttgcatg taaacatagc gtgtgaaccc tgagcagtca aagccacttg
    21601 gatctttacc gccccaaaca tatggagtac caatatattt gtaagcttct gctacgattg
    21661 ctgcaccatt cacacttcca gaaggagctg gagcaggtgt tacaggtttt ggttgttcag
    21721 gtgttggtgt tggcgttgga gccggagtac tacttcctgt gccgtttcct gtatcaacac
    21781 tttgatctgt tgatggtgtt gtaggcgcag gtgttgttga ttcttctgtt gttgaagatt
    21841 caggcactgt tgttgattct tctgttgctg aagattcagg cactgttgtt gattcttctg
    21901 ttgctgaaga ttcaggcgct gttgttgatt cttctgttgc tgaagattca ggcgctgttg
    21961 attcttctgt tgaagattca ggtgttgttg attcttctgt tgctgaagat tgtgtagctg
    22021 atgatgattc ttcagtcatt gaagattgtg tagctgatga ttcttctgtt gctgagcttt
    22081 gtgcagtaga tgaagcttga gtagcttgtg cttcagcctc tgcttgttcg cgtgcttctt
    22141 tttcagcttt ttcttgtgca gcttgttgac gagcttgttc tgctagacgt tgttgttcac
    22201 gaatacgagc ttgctctgct tcagcttctg ctttttgacg gttcaagtca gctttcttgt
    22261 cttcagcagt tgcttgttca gcagctaatg aagttttcag tacgttcaaa tcagcttgtt
    22321 tagataaaag atcgcctttt tgagattcca aagcagcttg gttttcagct aattctttta
    22381 gtttagcatc gttttcagct tttttgtctt ctacagcttt tttatcttgt ttttgttgtt
    22441 ccatcaagtc gttgtttgct tttaccatcg ttgtcattgc ttgaacgcgt ccaatagcat
    22501 ctgctaatga atcagcattc aatacagcat cgatgtagtt tgagcttgtg ttgcttactt
    22561 gtgcttcgcg tgcttgtttt tggattgtat cttcacgttt ttcaatacgt tcttgtaaat
    22621 ctgcaatgtc ttttactaat tgtgcagatt cttgacgcaa tgtatcttgt tttgctaata
    22681 ggtcttgtgc ttgtgtgttg atttcagaaa cttggctttc taaggcatcg atttgtgatt
    22741 gtgcatctgc ttgttgattt ttcaagtctg caatcttttg atcttgctgt tgtatctgag
    22801 aatcaaaatc gtccgccgcg gcagcgatcg gtgatgctac ggcagtcaag gtcattgaac
    22861 ataccattac tgctgatatt aaactctttt tcactcttca ttcctccgac tggcttaatt
    22921 taataaatat ctaaatatat ttaagtcttt cttaacgata taaaaattgt accatagcag
    22981 tgtgtcaacg atataatagt tatgttacaa aaatgtttca aaacaacttt taaaaatgac
    23041 aaaactgttc gtttcagaaa atgatcatga aaaagccgcg ttaagtctag catttcttaa
    23101 gataacaacg attctttttc gctttcgacc taaaaataaa aaaagaaatt attcatcact
    23161 gaataatttc ttaaagggaa aaatgaataa tacaaatata atcatgttca acagcagtgt
    23221 aggtcctaaa aaccttgtaa taaaatacgt gttatttact actgctaatt taaaaatcaa
    23281 ctggaccacc atcgtaaaca attcataacc cgtgacaaag atgatcatac tgaaaaattc
    23341 agtaaagatg ttgacatgga taacgtcttt cattacatac atcaaccata caattaaagg
    23401 gagagctact gcatagatac cgataacgcc aatatagtaa gcgtcataga tagccccgag
    23461 aacaatcgtg gtaatcagta aataacgttt ttcaaacgcc atactgcaac ataataatgc
    23521 caatatcaga aagtgggcat ttgacatata ggtgcctttc gaccactccc ctagcattct
    23581 tgttaaatga ccatctatca acatcaaaaa gaacaaaacg attggcagat agtacttcat
    23641 tgtttctttc ttcaacatgg actaatcctc cgctagccgt tggacaatcg tcacaactga
    23701 cacgtcatac atttctgcat aaggtttcac ataaacttcc cgatccagcc cataactatc
    23761 tggtttcgtt ttaataaccg taccgatcgg caagttagct ggagaattcc ctccaagacc
    23821 ggatgtctgg acaacatccc cttctttgat atccgtatca ccagttaatt gggtcaccac
    23881 taaggcatgg agcttttcat catagttttt aagcaaacca aacgcttcgc cattagccga
    23941 agatacccgt actggaaaat gattggagct ttcattagag gatgacagta attcgatttt
    24001 agacgaagcc gtattgacct cgatcactcg gccaatcaat cctttttgcg acatgactgc
    24061 catatttgct tcgataccgt ctttagaacc cttgtctacg atcagcatgt cctgccaact
    24121 gtcaggcgaa cgagtaatga catttgccgt tactttttcg taactagtca gcgtctgatt
    24181 caactcaagt tcttttttca acgcttcgat ttctctctcg taattcttgt tttgctgtga
    24241 aacgtcatca tagctatcga ttttttcttt tagccgctca ttttcggcat aagttgaaaa
    24301 aagattatgg acagaatcta ctccatttcg tacccaccgt actggggcag agattgtttt
    24361 atcaaccatt gcaacactgt cattaacgat ggattggaag aaattgggct ttccttcatt
    24421 cgctcgctgc gcagcggtca cacttagtat cgtcaccacg atgataacaa taaccaaggt
    24481 aataataata tttttattag gattgaactt cttcacaaag acacctcgaa ttaattagac
    24541 tcttgtgttc aattttatca ctaaatgccg tgaaacaaaa ggtaagttgc tcctcttaag
    24601 ctttttttta gcaaataata gattctgtca tttttagcct gaaagacaaa tttttttatt
    24661 tgtttatgga tcaatctttg ctttgaataa ctgcaatcat accatctgaa aaagaaaatt
    24721 ctgcggtatc tgaaagaaat tcgttacttg cataagatgt cggatattct acttctttat
    24781 tttccaatac atacttgctg ccttttaatg taagattcga gacgggagtc aagcagcaat
    24841 aagctaaata cttcatatct ggtatctgtc ttactatatg ctctccaggc aaataataag
    24901 acaaataatt ttgacaatct ctgataataa gctgatgggc aaagggtttg aagcgaggtt
    24961 ccatacctaa ccagagattg gctaaaagat gatccaatct tccgcccgta gctccaatca
    25021 aagtgacttc cgcttgcggg taacgttcaa atgtttttaa gatacctaac tgtgtatctg
    25081 tatcgtcttt ttctgcaggg gaacgggtat actctttggc ttttgcaaat acttccttct
    25141 gctcttcgtt cgacaatgaa tcaaaatcgc ccactgccag atctactggg tagcctgctt
    25201 gaagcaggta cagcgcacca cggtctatcc cgacataggc atcgtatttg gacagcagag
    25261 actgcggcca gttttgcgga ttacctccag cagctaataa aattttcatt tagtctaatg
    25321 cctcttttaa tcgttcgatt tgtccgactg gattttcggc tccatagata tatgatcctg
    25381 caacgaagac atccgcccct gcatctttac agatttttgc tgtttctgga acgattccgc
    25441 catctacttc gattgcataa gtccaattgt tctctctacg tagatcagcg agttccgtaa
    25501 ttttttctac tgtttcttca ataaagcttt gtccgccgaa cccaggattg acagtcatga
    25561 ctagtacttg atcagccaaa ggcaaaacat gtttgatcat ggagactggt gttcctggat
    25621 tgataactac tccagcttta actcctaagc tttttgtcat ttgaagtgcc cgatgaatat
    25681 gaggagttgc ttcgacgtgg acagtaatga tatctgctcc agcttttgca aatgctggaa
    25741 tgtagttttc tggatcaacg atcatcagat ggacgtctaa cggtaattta gtaacaggac
    25801 ggattgcctg aacaatattt ggccctaatg tgatatttgg gacaaattgg ccatccatta
    25861 catctacgtg gatgtaatct gcgcctcctt tttccactaa ctcaatgtct ctttgtaaat
    25921 tggcaaaatc tgcactcaaa atggatggtg ctatcttcat tcttgtttcc tcctattttc
    25981 gtttaccttc tttttttgca tacattggtt ttcttttttc gatttcttgt aagaattgca
    26041 aataattgtc gtaacgtgtc tgtgcgatac cacctgtttc tactctatgt tttacttcgc
    26101 agccaggttc tttagcatgc atgcactctc taaatttgca atggacagaa gcttctacaa
    26161 attcaggaaa ttgtctcggc agttctcctg cttcaattgt caaaaagtca atcgagctaa
    26221 atcctggtgt atctgctact aacccgccat agataggaat cagttccaca tgacgtgttg
    26281 tatgccgtcc tcttccaagt gcatcagaaa tctctcctgt tgctaaattc agttccggtg
    26341 atatttgatt cagtagcgtc gattttcctg ctccagactg acccataaag accgatagcc
    26401 gttctgggaa gtaacggatc agttctgtcg tatcacccgt atgattgggt acaatcaccg
    26461 gatagcctat tttagtatag gtttgcttga tctcttcgat tttttctggg tcgtctgaca
    26521 agtcggtctt tgtcaaaaaa ataatcggtt cgatcgactc gtattccaag gtaactagaa
    26581 agcggtcaag tagattataa gaaaatgcag gctctacgat acttgtgaca atgattccaa
    26641 gatcaacatt tgtgactggt gggcgaacta attgattttt tctcggcaag atttccagaa
    26701 gatagccgtc tgtttgattt tcactctcaa agatcacctg atctccgaca agcggcgtga
    26761 ttttccgatt ccggaaattt cctcttcctc ttgtttgata ggtctctccg tttgcgtata
    26821 catagtaaaa accgctgatt gcttttctga tttgtccttt gataagtgcc acctccgttt
    26881 ttgtttattt taccatacga agaggaaagt aggtgttatt ccatgcaaac ttctcaaagt
    26941 atatggcttg aaaattgatc aaaagagata gaaacacaaa aaagagaatg caacaaatca
    27001 atgtcgcatt cccttctgat atattttatt cagcacttat tttgaacttt ctgaggtgct
    27061 agctgatgaa cttgtggagc tggaagattc ttcttttgaa gagttgcttg tgctactgga
    27121 gctacttgag ctgctagaac tgtctgaaga gtctttttca gaactagaag acgctggatc
    27181 tggtccttta gagtaaatta cgttcacaac cattcctttg gtaattgtcg ttcctgcccc
    27241 tggtactgta cgaatcactt tatctttatc caccgtgttt gaatattcgg aagtctcatg
    27301 cccgatatat tctgcaccga cactagctaa ataactttgt gcttcgcttt ttgtatagcc
    27361 ggagatatca ttcaatttag gctctgttcc ttggcttacg acaaaattga tgtaagtttc
    27421 ttctgctaca acttcacccg aggctggatc ctgactgatg atcgaacctg atggtacagt
    27481 gtcgctatag tcataagtag cactaatatt attgatattg aatccttgtg taacaagcca
    27541 attacgaaca gtttcgtagt tttctcctac atgactactc aaagtcactg tttctggtcc
    27601 tttgctgact gtgaaagtaa tcgtgtctgt tttaggatcg acttctgtat cttctgatgg
    27661 agattgcgaa atgatcattc cgctttctac ctctgaactg aattcctctt ctttttgaat
    27721 caagtcagca gaaaacccta attctttcaa acttgcttcg gcatcttcat aacttttacc
    27781 actgtaatca tctaatttga tttttttcgt gccgctacta atatacagag tgacttcgcg
    27841 tttttgcttg actgtcgttc ccgctgccgg gtctgtcttc actacattac cttcttcgat
    27901 tttgtcatct gcaatttctt ctgtttttgt tgctacttct aatttcgctt ttgcgagtgt
    27961 ttctctagca gaagcttcag aaagatcaga aacatcagga acaacaactt ctcctcgccc
    28021 gccagaagca aagaatacag ctgttccgat tcctaaaaca gcaagaatag ctaataggat
    28081 cagccaccat tttttctgtc ctttcttttt aggatcaggc agaacttctt cctcctctgg
    28141 caaggtttcg ttttctggct tgtcttttgg cagaggcata gatttgaatg aatcaggcat
    28201 tggtgcatct tccgtaaggg gtgtgataac ttttgtttca ttatccatca catgaggctg
    28261 ccatttttct tcgtttgcac gagctggtga taatactgta gaaagatcat cagacatttc
    28321 ctcggctgac ttataacggt ctgcaggttc tttagccgtt gcccgtaaaa tcacgttttc
    28381 cagtgcttgt ggcacatttg gatcaagtgc ttttatagat ggaagatcat cttgaaaatg
    28441 ttttaaagca attgttacag cagattcacc atcaaacggt acgctacccg tcaacatctc
    28501 ataaaggatg atccctaaag cataaatatc tgactgcttc gttgccatac ttcctctggc
    28561 ctgctcaggg gacagataat gaacagatcc cagcatcgta ttcgtctgcg tgatcgatgt
    28621 ttcagataaa gcgatagcaa tcccgaaatc cgtgattttt acaacacctt cattatcgat
    28681 cagtacgttt tggggtttca aatctcggtg gatgatttga tggttatgag ctaaagaaat
    28741 agcagaaagg atctgctgca taatatttac tgctgtttca taaggaacag gataatgtgt
    28801 ttggatatat cgtttcaagt ccattccttt gacgtattcc atcaccagat actgcatgtt
    28861 gtcttcttca ccaacatcgt aaacactaac aatgtttgga tgaacgagtt ctgttgctgc
    28921 taaagcttct ctctgaaatc gtcgaatcgc agtctggtca ttttgaaagt caaatcgtaa
    28981 gactttaact gctacatcac gatccaagat taaatcgtgc gccaaaaata catttgccat
    29041 accaccgcta ccgatatttc cagtgatttg ataacggcca tttaattttt tgcccaactc
    29101 gatcatacac tgtcctcctt atattcgata agaagaacgg tgatattatc cgctccgcct
    29161 gcttcattgg cacgatcaat cagctcagtt actttatgag acaatgggcc ttcttgattg
    29221 atgatcgttc ctatttcttc ttcagacagc atgttcgtca agccatctga acataacagc
    29281 agtcgatctt ttagttgcca aagatgagta gaaacatcta cttcgactgt tccaggcatg
    29341 ccgacagaac gtgttaaaat atttttcctt ggatggttca ctgccatttc ttcgctgatt
    29401 tctcctgatt tgactagttc attgactaaa gaatgatcct ccgtcaattg catgatttta
    29461 tcttcacgaa tcaaataagc tctgctatcc ccaacattgg caatcgtgaa ccagtcatct
    29521 gacagagcgg ccgctacgat tgttgttccc ataccgttat attccggctg ttcttgtcca
    29581 cgctgataaa tcagcatatt ttcttcttga atcgattgaa tgaaccattg ggcgattttt
    29641 tcatcgtcaa cagcttcttg tttttcccaa gcttcgccta gattcgttac cgccatctga
    29701 ctggcaatgt ctccggcacg atgaccaccc atcccgtctg ctaatacagc aagcttgaga
    29761 cctgaacggc tggtaaatac actggcatag tcttgatttg tgttacgtcg tcttcctaca
    29821 tctgattgat attcaatctg cattttttca cctcattact ttttgcgcaa acaacaaatg
    29881 aaaaatccat ctgtgtaaaa ctgatgcgga tacaaagtca acattttctc ttcgattgat
    29941 gattgtagca taggattggt caaaacatca atcctctcaa aatcagggtg tctttccaag
    30001 aaagcagaaa caacgtcttg gttttcttct tttaagatcg tacaagtgct ataagtcaga
    30061 ataccggaag actttaaagt tggtgcgcag ctttctaaaa tttccaattg gatttttggt
    30121 aaattcgcta attcatccgg ctgtttttta taacgaatat ctggttttcg ccgaagcagc
    30181 ccaagacctg aacaaggcgc gtctactaaa atccgatcaa actgctctgc ttcgaactgt
    30241 ttactgactt ctctagcatc catcttttga gcgtagacag cagaagagac acctagacgt
    30301 gctgcattat cttcaatgag tttgactttg tgttcgtgta catctaaagc gaccacttct
    30361 ccaccgcatg acggatctaa aaaagaagca atatgcgtcg tcttacctcc gggtgctgca
    30421 caggcatcta agacatgatg ttcaggctcg atttgcatag acggcgctac aagcatcgaa
    30481 ctttcatctt ggatcgtcat gacgccatcg tggaacaatg agctagaagc taaatgccct
    30541 tttttcgcta ctataccgta tggactgact tggctttttt cagctgtgat ctcttcttct
    30601 tgcaaaacag tgatggcctg atctctggaa agtcggcgtg tatctactcg ggcactagca
    30661 tggctaggct gatatagcga taaaccgagc ttttcagttt cttcgtatcc gatttgatcc
    30721 accagtcgtt tcgtcatcca tagaggcagg ctgattttga cagaaagtct ttcgatagga
    30781 tcagcaatgc cttgcagatc tggtgctcct tgacgctgat aattcctcaa gacaccattt
    30841 acaaatttcc ctgtcccagg atttcctttt acttttgcga tttcgaccgc ctcgtttaaa
    30901 atagcatgtg cagggacttt atctaaaaat tctaattggt atacagaaag ataaagaagc
    30961 gtcttgaccc agtcatccac tttttttgct ttagcgatca atggtgcaac gtaaaattcc
    31021 aatagtcgct gatggctaat cgtaccatag atcaattctg taaataaacc cacatctttt
    31081 tgatttagct cgctttgttt gatcatctca ttcaacaaaa gattcgagta ggcgccaccc
    31141 ttgttcactc gctctaatgt cagtaatgcc atatatcgta ctgatttttt cattttttta
    31201 gggatttttt tcattatttc acctgctgac caatctgaac ttgctgaccg cttccgttaa
    31261 ggaaatcatg tacggcctgt tttcctttac cagctggctg taattcattg atggctaaga
    31321 cggtctgttt accgcaagca atccatagat tttttttgtc tttccggatg atcgtaccag
    31381 gtgctttgtc tgtagtttct gccaatactt caaccgataa taatttccag cgtatgccct
    31441 cataggtcgt gaatgcaatt ggccaaggac gcattccgcg tacttggttg tcaatttctt
    31501 ctgcagtttt atgccaatcg attgcttctt gttcccgtgt gatgtttggc gaaaaagttg
    31561 cttctgactc gtcttgaggt actggttttt gtccatccaa aatattgggc aatgtttcta
    31621 gcaatagctt tcttcctaaa aggctaagct tttcaaacat cgtccctaca tcatcttgtt
    31681 tagtgattgg tatgctttct tgcgcataga ttccgcctgc atccattttt ttgatcattt
    31741 ccatgatcgt tacaccagtt tctttctccc cattcatgat ggcataatga acaggcgcac
    31801 ctccccgata tttaggaagt aaagaagcat ggacattgat tgcccctaat tttggtactt
    31861 gcaataactt ttcaggcaag aattggccaa atgccgcagt gacgatcaca tcaggcacca
    31921 attcaatgat ttcttccatt tctggcgaac cggagatttt ctctggctgc agcacacgga
    31981 taccgtgctt cagagccgct tcttttaccg gtgtcggcgt aattactcgt ttccgcccaa
    32041 ctggacggtc gggctgtgtt accactgcct ggatctcgta acctgattct atcagccctt
    32101 caagaatcgg cacagaaaaa gcaggtgtgc ccataaatac tagcttagtc atcaagatgt
    32161 tcctccatat attcttcaag ttcttcttcc gggatctgct gtatcatttt ctcaatgaac
    32221 aagataccgt ctaagtgatc gatttcatgc tggaaggcac gggctaaata gccaaaagcc
    32281 gtcacttcta tctcttctcc gtctcgatca taataacgca cggtcacttc atctgctcgc
    32341 ttgaccgttc catagacatg cggaatactg agacaacctt ctacgtcaag gctttcacct
    32401 tttgcttcga tgatttctgg gttaatcagt tcaaatttct cgccttcatc tacttcgatc
    32461 acagcaattc tcttgttttg tcctacttga ggagcagcga tccctattcc gtcattcgca
    32521 atcattgtct catataaatt gtctaataaa gcgattgtct cgtccgtgat tacatcgatt
    32581 ggctgagcag ttctttttaa tttatcatta gggtggatca atataggata gcgcataatt
    32641 tggccctttc ttaaataaag tttaatggtt cgttgtcaat tgccacaaaa agaccttgtc
    32701 gctgttcttt ctggcttcca ttcaaaattt catccaaaac atgaggaaga ttcggttcat
    32761 gtttatattt gatgattagt tgataataat atcggttttt cactctcaaa atcatgctgg
    32821 gcgttggccc taatagcaag ctttgagggc ttaacacttc ttttagctga ttggcaatct
    32881 gaaagatttt ctttgccgct acttgttctt caggatggct ggcggttatt ttcacagtaa
    32941 agtaataagg aggatagcct ccacgatgcc gtacatgcat ttcctgctga taaaactgct
    33001 cataattttg ttttttagct aattctatgg cgtaatgttg aggattgaat gtttggatca
    33061 cgacttcgcc tgctttttcc gctcgccctg ctcgtcctga aacttgggta agcaattgga
    33121 atgtatgctc actagaacga aaatccggta aattcaggga ggtatcagca ttcaacaccc
    33181 caactaatgt cacttctgga aagtccaaac ctttagcaat catttgtgtc cctaataata
    33241 tatctgcttc ttttgcaccg aatttttgta aaatctgttc gtgtgcccct tttcttcgag
    33301 tggtatctac atccatacgc aaaatcctag cttgcggata aagttctcgg agttcctctt
    33361 ctactttttg agtacctgtt ccatagtagc ggattttatt gccgccacaa ttaggacagc
    33421 gattgggaat aggttcttca tgtccgcaat aatggcagcg cattgaacgt gtatccatat
    33481 gcagtgtaag agagatatcg caattaggac atggaagaac aaatccacag tccctacaca
    33541 tcacaaaaga cgaatatcct cgacgattga gcagtaggac agtttgttct tttttgtcta
    33601 atcgattttg tattttttcc tgcaaattag cagaaaaagt agaggtccga tgattctgaa
    33661 actcttcacg catatctacg atctcaatag ctggaagctg tgcagctgct ttggctcggt
    33721 ggtttaactg caataactga taaacgcctt tttgagctcg tgctcttgat tctaaagagg
    33781 gcgtcgcgct tcctagaact attgggcaat gatgatattt actgcgccaa attgctagat
    33841 ctctcgcatg ataacgcggt gtctcatctt gtttgtaact tgattcatgt tcttcatcga
    33901 taatgatcag cccgatattt ttcagcgggg caaaaatagc agatcgtgcg cctactacta
    33961 cttgcgcttc ttcccgctca atcttgcgcc attcatcata tttttcacct tgggaaagtc
    34021 cgctatgtaa gaccgcaact gattctccga agcgtccttt gaatcgctcg accatttgcg
    34081 gagtcaatgc gatttcaggc actaacataa tagccgtttt attttctgac aaaacatcag
    34141 cgattgcctg aagatatact tctgttttcc cgctgccagt gattccctcc agcaaaaaga
    34201 cctgatcttt ttgctgctga cctgctgtga tgatttgttc gacagcattt ttttgttctg
    34261 cattcagttc caatgccgtc gtttggtcaa atactcggtc tttataaggg tcgcgataac
    34321 gttctgattc tataaactcc agccagccct tttcttttcc ttgattcaag acagcagtac
    34381 tgattccttt atttttgaaa taagcaattg gttcttcttg gctcagttca gataaacaca
    34441 aaagaagttc tttttgtttc ttggcatttt gccgtaattt tgcccattct tcttcgattt
    34501 gcttttcagt taacaaagaa cggaccaaac gaatcgtttt tactttattt cgtgtatgga
    34561 cttcatattt gatatctact aattgctctt ggcgccagcg aatcaattga gaaaggctgc
    34621 cttcttcttc tgcttccttc caggaaatca cttctcgctg atcaaacaat acctgaactt
    34681 ctggtgtgtc tgccaaagga tagatcaatt tatcatattc tgctttcatc acactcggaa
    34741 gcatcgtttg tagacaagtg attttgaatg cgtaagtaat ttttttcata taatcagcta
    34801 atgaaagtaa ttcttcattg accaccggag caaggtctag caaacgaata actgccttca
    34861 aagatggatt agctgattct tctgattttt ggatagccat aacaaatcct tggacatgac
    34921 gattgccatt accaaaaggg acttctactc gcatcccgac ttgcaaagct gtttccattt
    34981 cagagggaac caaataagtg aatggctgat cggtctgcat agtaggtacg tccacaatga
    35041 cttcagctgt taatgtcatg gttcgtttcc tccttttttt gtcttttctt atcaagcgac
    35101 aaaaagttcc ttgcctattt tactagagat cgatggattt gtcttatctt ctgccaaatc
    35161 ctaacaaaaa attaacagca gataagaaaa aaaagaactg tgtcaaaaag ttcagacaca
    35221 gccttttcta ccagacaata agtggcgaat gtttgaaaag gaaacagctg ggtttgcttt
    35281 tctttttaga tgttcgctct atttttcttt attacatttt ttgctcttca cggatacgtg
    35341 attccaattc gtgttgttca cgctcttttt gtgcttgacg ttcctcttct tccatcttca
    35401 aacgttcacg ttttaattca ggatgtggat cattgactac atttcctgca tcgatttctt
    35461 ctaaagcttg accgacgctt tttactgaat caaaagaatc tagagtaggc tgtgcacttg
    35521 catccaattc atgcgcgcgt ttacttgcta aaatcactag agaatatttt gaatttacac
    35581 gatctaatag tgagtcaatt gaaggtttta acatcataag actacatctc ctttaacatt
    35641 ttaatatatt taccgattac gcgatctact cgaaaatgtt cactggcaat aatgtttttg
    35701 attcgttcaa ctgctagcgg cacttcatca tttacaacag catagtcgta aagagccatc
    35761 atttcgattt cttcttttgc aactttcatt cgttcttcga ttacttcatc tgcatctgtt
    35821 cctcggccta cgatccgtga ttttaattcc gctaaatctg gcggagtcaa aaagatgaat
    35881 acaccatcgg gcactttttc tttgacttgt tttgctcctt ggacttcaat ctccaagaaa
    35941 acatcttttc cttcatccaa tgtcttgttg atatatgaca aaggagttcc ataataattc
    36001 ccgacatatt ctgcgtattc cagcatctct ccagcttcga tcattgattc aaactcttct
    36061 ttgcttcgga agaaataatc aacgccttcg acctcccctt cacgcatttt acgggtagtc
    36121 attgagatcg aatactgaaa atcattatcc tcactctcaa aaattgcttt tcgtactgtg
    36181 ccttttccta caccggatgg accagacaac acgattaata atccacgctc tgacatgacg
    36241 acgtcctttc aactagtctt tttgtactta tcgtttattt tgcacttttt ttctgcaact
    36301 ttcaaggtta tctttaatta tagctagaaa ttggtaaaaa agctaccctg taccaagagg
    36361 tcgtaaaaaa gctgtcctgc atcaagtaat aagaacagcc aaacataaac agcttctcat
    36421 gtttttcgtt tggttggggt tattatcgca gatgcaagct tttgaacgcc gtgtataaga
    36481 ggtcgtgaag aagccgatta gtttcgagta tgaagaaaaa ttttgtgaaa atagtttctc
    36541 acatttttgc ataaatttgg cttaata
//
LOCUS       DAXQKX010000023        35381 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.023, whole genome shotgun sequence.
ACCESSION   DAXQKX010000023 DAXQKX010000000
VERSION     DAXQKX010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35381
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.023"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(91..1110)
                     /locus_tag="ACF3MF_001286"
     CDS             complement(91..1110)
                     /locus_tag="ACF3MF_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFE3927291.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(1132..2139)
                     /locus_tag="ACF3MF_001287"
     CDS             complement(1132..2139)
                     /locus_tag="ACF3MF_001287"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFE3927292.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            complement(2132..2797)
                     /gene="pgmB"
                     /locus_tag="ACF3MF_001288"
     CDS             complement(2132..2797)
                     /gene="pgmB"
                     /locus_tag="ACF3MF_001288"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFE3927293.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            complement(2790..5084)
                     /locus_tag="ACF3MF_001289"
     CDS             complement(2790..5084)
                     /locus_tag="ACF3MF_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HFE3927294.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            5344..7509
                     /locus_tag="ACF3MF_001290"
     CDS             5344..7509
                     /locus_tag="ACF3MF_001290"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HFE3927295.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            7813..8646
                     /locus_tag="ACF3MF_001291"
     CDS             7813..8646
                     /locus_tag="ACF3MF_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HFE3927296.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(8748..10448)
                     /locus_tag="ACF3MF_001292"
     CDS             complement(8748..10448)
                     /locus_tag="ACF3MF_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927297.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            10955..12115
                     /locus_tag="ACF3MF_001293"
     CDS             10955..12115
                     /locus_tag="ACF3MF_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFE3927298.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            12131..12574
                     /locus_tag="ACF3MF_001294"
     CDS             12131..12574
                     /locus_tag="ACF3MF_001294"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFE3927299.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(13057..13587)
                     /locus_tag="ACF3MF_001295"
     CDS             complement(13057..13587)
                     /locus_tag="ACF3MF_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HFE3927300.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            13692..14243
                     /locus_tag="ACF3MF_001296"
     CDS             13692..14243
                     /locus_tag="ACF3MF_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFE3927301.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(14396..14869)
                     /locus_tag="ACF3MF_001297"
     CDS             complement(14396..14869)
                     /locus_tag="ACF3MF_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFE3927302.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            15007..16479
                     /locus_tag="ACF3MF_001298"
     CDS             15007..16479
                     /locus_tag="ACF3MF_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HFE3927303.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            16476..17186
                     /locus_tag="ACF3MF_001299"
     CDS             16476..17186
                     /locus_tag="ACF3MF_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HFE3927304.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            17538..17822
                     /locus_tag="ACF3MF_001300"
     CDS             17538..17822
                     /locus_tag="ACF3MF_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HFE3927305.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(18103..18522)
                     /locus_tag="ACF3MF_001301"
     CDS             complement(18103..18522)
                     /locus_tag="ACF3MF_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HFE3927306.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(18524..19108)
                     /locus_tag="ACF3MF_001302"
     CDS             complement(18524..19108)
                     /locus_tag="ACF3MF_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HFE3927307.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(19155..20630)
                     /locus_tag="ACF3MF_001303"
     CDS             complement(19155..20630)
                     /locus_tag="ACF3MF_001303"
                     /EC_number="4.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HFE3927308.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            20811..21122
                     /locus_tag="ACF3MF_001304"
     CDS             20811..21122
                     /locus_tag="ACF3MF_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927309.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(21237..23573)
                     /locus_tag="ACF3MF_001305"
     CDS             complement(21237..23573)
                     /locus_tag="ACF3MF_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HFE3927310.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            23715..24383
                     /locus_tag="ACF3MF_001306"
     CDS             23715..24383
                     /locus_tag="ACF3MF_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFE3927311.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            24386..25429
                     /locus_tag="ACF3MF_001307"
     CDS             24386..25429
                     /locus_tag="ACF3MF_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFE3927312.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(25666..26547)
                     /locus_tag="ACF3MF_001308"
     CDS             complement(25666..26547)
                     /locus_tag="ACF3MF_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFE3927313.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTESDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            26706..27434
                     /locus_tag="ACF3MF_001309"
     CDS             26706..27434
                     /locus_tag="ACF3MF_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HFE3927314.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            27590..27907
                     /locus_tag="ACF3MF_001310"
     CDS             27590..27907
                     /locus_tag="ACF3MF_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFE3927315.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            27900..28508
                     /locus_tag="ACF3MF_001311"
     CDS             27900..28508
                     /locus_tag="ACF3MF_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HFE3927316.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            28563..29354
                     /locus_tag="ACF3MF_001312"
     CDS             28563..29354
                     /locus_tag="ACF3MF_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="HFE3927317.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            29492..30004
                     /locus_tag="ACF3MF_001313"
     CDS             29492..30004
                     /locus_tag="ACF3MF_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HFE3927318.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KIKKVTLDIY"
     gene            30030..30902
                     /locus_tag="ACF3MF_001314"
     CDS             30030..30902
                     /locus_tag="ACF3MF_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFE3927319.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            31078..31440
                     /locus_tag="ACF3MF_001315"
     CDS             31078..31440
                     /locus_tag="ACF3MF_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFE3927320.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            31449..32201
                     /locus_tag="ACF3MF_001316"
     CDS             31449..32201
                     /locus_tag="ACF3MF_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3927321.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVKPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            32215..34017
                     /locus_tag="ACF3MF_001317"
     CDS             32215..34017
                     /locus_tag="ACF3MF_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFE3927322.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAEKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            34294..35334
                     /locus_tag="ACF3MF_001318"
     CDS             34294..35334
                     /locus_tag="ACF3MF_001318"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFE3927323.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
BASE COUNT        11054 a         6255 c         7288 g        10784 t
ORIGIN      
        1 cagataaaca atgtgttaga agtagtatct tcttttacat aaaaagctga ccataggata
       61 aatggtcagc gtatttagtg agtcagctat ttagtatggg ttttctaaag gaacgactgt
      121 ctctcttttg atcaagcgat gagggatgac caaacgtacg ccactgctca attcttcatg
      181 gatcaattcg cgcagctttt gcatagcgac acgtcctaat tcggagatat cgatatcgat
      241 acttgtaagg taagggtgtg ttaatgttga gaagatcgag ttgttgaagc taatgacgga
      301 gagtgtctct ggaatgacat agccatacat ttgcgccaac tgcatcgtgc gaagggcgaa
      361 gatatcgtca atgaccacca atgctgtggc ttcgttttct ttcaacgttt tctcaaagga
      421 cagataatcc tccggatgct ctagtactac actggataac gcaggaagac cagccatcat
      481 cattgctttt tgataaccga aatatcgttc gaaatacaaa ctttcatgag tcgtgtttgt
      541 cacaaacagg atattcttat gtccattctg gatcaaaaat tctgttgctt gtttacctag
      601 aagctggtta tcattatcta cataaacgat ttcgttctca tgatgataag gctgtccgat
      661 caaagtgaaa gggatgtggt tttggtataa ataatcaatg acagtatctt gactatctga
      721 atacactaga ataaaaccat ctacttgttt ttgtaaatgc atacgctgga cgttctctaa
      781 cagcaattca aaatttttag cagtagcgat tgctgtagtc atatcataat tccgcgcttc
      841 ttcgttgatt gcttccatga tctcaagata aaatgggtta ccgatccgct cttttgaatc
      901 aagagggggt aagattacgc cgatggcact ggaaatgcgt tttcctagat tgcgggcagt
      961 catgttagga acataaccta gttcatccat aatttttcgg actttcttct ttgttgtctc
     1021 ggaaatacta ggatgatcgt tgatgacacg agagacggtc gaggtggcaa caccggcttt
     1081 tttcgccaca tcttttacgg taatagccat gataaaaaca cctttctctt gttattgtgc
     1141 agagaaccga taaatcgtct gactgatccg ttcttgacca ggatggaggt tgatcgatcc
     1201 aaatttgggg aaatgaacga tatcagggat ttcttgcggt tcgattgcta atccgtagtt
     1261 tgaatgcatc tgttttccat tgacagagaa atcagcttcg aatccagtcg tagaaaataa
     1321 taccatactt ttattagaag ttgctatagt catttggcga ccagaatgct tctcgaataa
     1381 ttgtaaggaa gttttggaaa gcctaggatg atgcaaaaga aatacatcat ctagtccatc
     1441 tggataacat gcaaggatct cttgcagtgt tggggatttt ctaaagtcga ttggcagttt
     1501 ttcttttttt gtccaatttc cagtaggcag tttttcttga tctaattcaa gcacaccatc
     1561 taaaaagacc gttaactgat gttcatagat gtctcttgtt ccatttcctg aaaggttgaa
     1621 gtaggcatgg ttggtcggat tgcagatggt ttcaacaagg ctactagcag aggttgtcat
     1681 ctctaattcg ttttttgtta aacggtaagt gatcgtagca gtgattggtc ctggataggt
     1741 agaaaattca tcttttaagt aaaagaccac acctattgat gatggagttt tgaaaacttc
     1801 tacttcccaa aattggaaag accagccttt cgtgccaccg tggatatggt gtgatccgca
     1861 gtttttctcc aatctatgct caccccaaga agcatcccgg atccttccgg ctacaggtcc
     1921 gacagttgct ccaaaaaagc ttttgtctgt tagaacatct tcgaaacgat cgtaagacaa
     1981 taaaacattt tctgattttc cttctttgtc tggtgcgaag atttggtgca ggcgggcacc
     2041 gtaattgaga agaacgactt ctaagtagtc gttcttcaat gtgattttct ttatttcagt
     2101 ctctggaact ggtacgacgg agatctctgg attatccatg gtcatgccac ttttctttca
     2161 agtaatcgat cgtaagaaaa gtcgtatcag ggacaagcgg gatctcctct ccaaggtctt
     2221 cagcacgtcc cacgccaatt ggttgagcgc cacttgagag gatggcttgg ataccggctt
     2281 gcgcgtcttc gatcccgata cattcttctg cttttagtcc gacagctttt gctgcaagga
     2341 ggaagatatc tggcgcaggt tttccgtttg ttgcttctgc cgggtcggca atagcatcaa
     2401 agtaaggtgt aagacccatt ttttcaagta ggaatggccc gtttttactt gcagaagcaa
     2461 gagcaatctt gattttttct tcttttaaag aatccagtaa aggcacgacc ccggggaaga
     2521 catcttttgg ttcgatcgtc tggatcatct ctaaataata atcgtttttt cttttcgcta
     2581 attctgcaaa ttcttccttt gaaaaagagt gttcttttcc gccataagct aaaagcaaag
     2641 agagtgagtc ttctcggctg acgcctttta gctgttcgtt gaatgtgtgg tcgatcgtaa
     2701 tgccgatttc ctgaccaagc tttcgccaag cacgataatg gaattcagca gtatcggtaa
     2761 tgacaccgtc taaatcaaac aatacccctt taaacatttg cttcctcctt tcttagcgtt
     2821 atttctagac gatccgctaa agaataagac tgttcataga cgtaaatttc tagaggagaa
     2881 ccttctaata actcgaaagt aacttgttca tctgtgactg agatgaacaa taaacgtccg
     2941 cgataattga tatggaaaga ataagctttc caagtttttg gcagaaatgg tgcgaatctc
     3001 aactgatcat gggcagtttt catttgagca aatccttgga caatcgacaa ccagctacca
     3061 gtcatggaag tgatgtgcaa gccgtcttct gtgtcgttat tgtaattatc caaatccaag
     3121 cgagctgttc gctggtacat ttctacagct ttgctttcca ttcctaattc tgctgctaaa
     3181 atcgaatgga tacttggcga aagggaagac tcatggacag tcattggttc atagaaatca
     3241 aagttttttt gcttttcttc ttttgtaaaa gtatcattga agaaataaat cccctgtagt
     3301 acatctgcct gcttgatgaa gcaagatcta aggattttgt cccaagacca atgctgattc
     3361 agaggaagat cgcttgtggg aatatcggat acaggcatga gatctttatc taagaatgtg
     3421 tcatgctgga caaagattcc taattcttcg tcaactggga agtacatgtt ctctgcgata
     3481 tctttccatt tggctagttc ttcttcgctg atagtgatag cagcttcttt ttgataagtt
     3541 aaataatttt ctcgcgtgta acgcaagacc caagctgcga tcgtatttgt ataccaattg
     3601 ttattgatat tgttctcata ttcgtttggg ccggtcacac cgtggatcat gtatttattt
     3661 gctcgttttg aaaaatggac acggtctgcc cagaagcgtg cgatttctgc taaaacttcc
     3721 agtccttcat ttttcaaata ttccgtatcg ccggtgtaat tcgtataatt gtagattgca
     3781 taggcaatcg cgccatttcg gtgaatctcc tcgaatgtga tttcccactc gttatggcat
     3841 tcgacaccag tgaaggtgac cataggataa agcgcgcctt ttaatccttg ttgctgagcg
     3901 ttgtggattg cttgcggcag ttgattatgc cgatatttca gcagattctt agttacttca
     3961 ggtttggcta aagcaagata aagagggaca gcatacgctt ctgtatccca gtaagtggct
     4021 ccgccgtatt tttctcctgt gaatcctttg gggccgatat tcaatcgttc atcttcgccg
     4081 tagtaagtag agaatagttg gaacaaattg aatcgaatac cttgttgtgc ttcttcgtct
     4141 ccttcgatga ccacatcggc aagcttccat cgttctgccc aagccgctgt ttgctcttct
     4201 tttgcttgga tataattgtt tgtctggttc gttaattctg agacagcttt ttctgcttgc
     4261 tgcgcttctg gaatatctct actagtaaga acgataattt ctttttccac tgaccatgtc
     4321 tcaccttgag ataattctgc agacaagcaa ccatgtaatg ctaaagtatc ttcgtgatag
     4381 tcagggatga ctgattttcc attaacgaaa tggcgcattg ctgcagtaac agtaaattgt
     4441 tcaatcccaa agttgtttgg aatagtttta gtcgtcaaat agccgatttc ttctatagtt
     4501 ccacgatcaa tctcattcca aaaatgttca tcatagttgc tgtcttcgtt ttgaacattt
     4561 ccatccaatt ttgatacgag tttgactgtt ccgctacctt caagcatttc tatagttaaa
     4621 tagatataag ctgattcttt tttgacaatg ctcagaaaac gttcgaagga aatgcgtact
     4681 ttattagtag aagtagtgat tgtgaatgta cgagataata caccattttt catatctaat
     4741 tcccagtaaa agtcttctgg ttccaaagaa gccaagtcga tcagctgatc gttgatcgaa
     4801 atatctatcg cgataaagtt caaggcgttg atcacttttc caaagtattc tggataacca
     4861 tttttccacc agccgacacg tgtcttatcg ggataccaga cacccgccaa ataagtacct
     4921 tgatggtggt cccctgagta agtttcttca aagttcccgc gcatccccat ataaccgttt
     4981 ccaatacttg ttaaagattc ttgcagtcga agattttttt tatctaattg tgtcgtgctg
     5041 attttccatg gatcaatagc aaatagtcgt ttgatctgtt tcatttttct cctcctaatg
     5101 agctgtttta tacgttcata ataaacgcaa ccgattgcac aagtcaatag acaaaagaaa
     5161 atatttcata gaaaaaagct taaaaaaata aatttttagg agaaaattat agaagggaac
     5221 acacgtatta taggttttat agaatggtat agacagaaaa ataaaaaata aagcatttac
     5281 aaaaaagaaa acgcacgcta taatacgttt aacgaaaccg attgcgtaaa ggagctaaac
     5341 ggaatgaaaa agatatttag ttttgaattt tggcaaaaat ttggaaaggc tttaatggtt
     5401 gtggtagcag ttatgccggc agctgggttg atgatcagta tagggaaatc aattcccttg
     5461 atcaatcctg attggacgcc gcttgtcaca acgggcggag taattgaaaa tattggttgg
     5521 gcaattattg gtaatcttca tattttattt gctttagcaa taggaggaag ttgggcaaaa
     5581 gaaagagcag gcggagcatt tgcagctggg atctcattta ttttaatcaa tcggatcact
     5641 ggggctatct ttggtgtcac aagtgacatg cttgcgaatg aagatgcatt tacccacact
     5701 ctgttcggta cgaagatcat ggttaaagga ttttttacaa gtgtattgga agcaccagct
     5761 ttgaatatgg gagtattcgt agggatcatc gctggatttg tcggggcaat ggcttataat
     5821 aaatactata attatagaaa attgccggat gctttgtcat ttttcaatgg aaagcgcttt
     5881 gttccgtttg ttgttatctt atggtcaaca atcgtggcat tgattcttgc tgtggtgtgg
     5941 ccaaacgtac aggctggaat caataatttt ggtttatgga ttgcagaatc acaagaaagc
     6001 gcaccgattc tagcaccgtt tttatttgga acattagaac gtttactatt gccatttgga
     6061 ttgcatcata tgctgacgat tcctatcaac tatacacagc ttggcggatc gtatgagatt
     6121 ttatcaggcg cacaggcggg gacacaagta tttgggcaag atccgttatg gttggcttgg
     6181 gccactgatt tagtgaatct taaaggtgca ggggatatgt cgcaatatga gtttgtgttg
     6241 cataactgga cgccggctcg tttcaaagta ggacaaatga ttggttcttc aggtatcttg
     6301 atgggaatgg cttttgcgat gtatcgtaat gtcgatcctg ataagaaagc aagatataaa
     6361 tcaatgtatt tttcagcagc gttggctgtc tttctaacag gtgtaacaga accattggag
     6421 ttcatgttta tgtttgctgc tgtgccatta tatgtcattt attcagtgat ccaaggggct
     6481 gcatttgcga tggcagatat cttgccattg cgggtccatt catttgggaa tatcgaattg
     6541 ctgactcgga caccgttagc tatcaaagcg ggtctaggtg gagatcttat caacttcgtg
     6601 ttgtgtgtga tcgcttttgg tgttgttacg tatttcttag caaatttctt gatcaaaaaa
     6661 ttcaactttg ctacaccggg acgtaacgga aattacgaca atgacagtga agaaaccgtt
     6721 gtatctaaca gcggaacagg aacagcagat cagcaagtgg tccagatcat tcatttgctg
     6781 ggaggaaaag aaaatatcaa agatgtcgat gcttgtatga ctcggttacg cgtaagtgta
     6841 aatgatcgag aaaaagtagg gactgaagaa gcctggaaac gagcaggggc gatgggattg
     6901 atcgtcaaag acaatggagt ccaagcagtt tatggaccaa aagcagatgt cttgaaatca
     6961 gatatcgaag atctgctgca atcaggagca gagattccag agccagaaat ggtttctaca
     7021 ggaaatggac aagcaggtag taagcaatac ttaggtatag aacaagaact agtttccgca
     7081 gcttctggag aagtgattcc tttatctgaa gtaaaagatc cggtattctc acaaaaaatg
     7141 atgggtgacg gctttgctgt tattccaaca tcaagagaag ttgttgcgcc gatcgctgga
     7201 aaagtgacaa gtattttccc tagcaaacat gcaattgggc tggaaacgaa agatggtatc
     7261 gaagttttga tccatatggg aatcgataca gtccaaatga atcagccagc ttttgagatt
     7321 gctgtcaaag aaggccaaga agtaggaaca ggaacgaaat tagctgagat ggatcttgat
     7381 gtgatccaaa acgaagaaaa agatccaacg atcatgatcg tatttacaaa cgataaagta
     7441 gaagaagtag tgatcaagca attaggtaca gtgacagctg gtaaagtgat cggctccatt
     7501 aaaatgtaag gagaggttgt gaaaaagctg tcctgcatca agtcataaga acagccaaac
     7561 aaaaatagct cctcctattt ttcgtttggt tgggcttatt accgagaagc agcagtttga
     7621 atactgttta gtggagaggt cgtgaaaaag ctgccctgca ccaagtgata aaaacagcca
     7681 aacaaaaaat agctcctggt ccattgagct tattactgag gagttagcag gagaacacta
     7741 tttgctggag aggttgtgac aaaaattttg tcacaaccct tttgtttcga aatgaagaca
     7801 aggagaaaac caatgaaatt catgacactc aacacgcata gctggcttga gccagaacca
     7861 gagaaaaaat tgcaagaatt agcagataag atcctgttag aagattatga agtgattgct
     7921 ttacaagaaa tcaaccaatt actggaatct gaagaagtag aacctgcgaa gctaatgaag
     7981 ttctgtccgg taaagaatca agtacctatc cgtaaagata attttgccta ccgtttagtt
     8041 cagcttttaa aggaacacgg aaaagagtat ttttggagtt gggaaatgag ccacatcggt
     8101 tatgataaat atgaagaagg aaatgcactg cttacgaaaa aaacattgga aagtcaggtc
     8161 cttaccgtct cccaatttca aaagaaagaa gattatcaga cacgcaagat cttgattggg
     8221 aaaacaaaga tagatgatca ggacattttt gtctcgagct gccacttttc ttggtggaca
     8281 gataaaaaaa gtggctttta ttttgagtgg aaaaacttgg aaaactactt tttggaaact
     8341 cgcgtaccac tttttttcct aggtgatttc aataatccag tagactctca aggttattat
     8401 actgtaagag aaagttgcct tcttcttcaa gattcgtatg ttgtcgcgaa tgaaaaagga
     8461 aaagcagcta ctgtggaaaa gaaaatagat ggttgggaac aaaatacaga aaaattgcgt
     8521 atagatttta ttttcgtccc tgaaggaatg caggttaaaa aatatcaacg gatttttgat
     8581 gggatcgata gtccaatcat cagtgatcac tacggggtgg aaatcgaatt agatgtgaac
     8641 gaataaaaaa tataacatat aacataaaaa aactgattaa aataaaactc tccaaacgat
     8701 tataccgttt ggagagtttt ttgatcggat gtatttatcc cttttgccta agcacgtaaa
     8761 agcttgtatc tatgataaat aaataaacat agcaaggtaa accagccaat caaagtaaga
     8821 gaaagaatga aatagaaata gattggcgtt tgataatgaa gcgtgagctc gttgattcct
     8881 ttttgctgct tcacgattgg ggtcccgata tctgttactt cataatcagt caatgttttt
     8941 ccattttgct gtagcacagt ccgatcgtag acgataacag ggatatgaac agttttgtcc
     9001 ccagtgtttt tccacttgat tgtcaaaaga ccgcctggat gtgtttttat aaaagttgtt
     9061 tcgttttcta gtatttcttc gttataccgg tcgtatttat tgtcttttgt ctccttatag
     9121 attggcagat agtcaggtgt ggttttttgg aaaacgaaca agctggtaga catatctttg
     9181 ctgaagaatg ttttccttgc ttcttccggc gtatcgaata gataagtatg tcgactgaca
     9241 aatgtttcat tttcccactt ttccagatgc tggtataagt tctggatcgt ctgtgctgaa
     9301 aaaataagaa tgccaaatat acttaaaaga cggaaccact tttgttcaga ccactggttc
     9361 agtgaaaggg caaggtaaag tagaagcaat agcgtaaatg gcacgaaaaa tcgaaatgga
     9421 aactggatca aactaataaa aggcacattt ttttcgatca atgtcgtcca tggaatcaag
     9481 ctagtagaaa gaaaaaagaa aacaagactt gtgtacaaca cgattttttg gaataaggtg
     9541 ttcttttgtt gaaagaaaat aaaaagcaaa aaacctgata atatcaatat aggaaaggcc
     9601 ttagggtaat ggagccaata actgccatcc agatctatcg ccttttgact catttctctg
     9661 ttaacaaagg gaggaagaat cttattccca ctgtaaacaa tagctaatcc tgcccaaata
     9721 tttgctgtca gaacaaaata aagcaagacc gacttaatca gttgaagcag tgcttttcct
     9781 ttttcagtct ggttaaaaaa gtaataaaga taaaaaggga tatacatcaa agctaacatg
     9841 atcgaagaca gtaaatggat ctgtgtcata agtcccactg agacagcgac tttgataaca
     9901 gggaactttt tatgaaggac gaaatcagca atagggatca tacataaagg ataaaaacaa
     9961 gtcccccagc tagtgaatcc ttggttgata gaccagtatt gaatagaata cgtactcatg
    10021 aataaaacgg ctactggtac acttacccaa tttcgaacat tgacatatct cagtaaaatc
    10081 agcatagaaa atcctgaaat aagataaaga atgaaatttg aaagaatctg ataatgaaac
    10141 cagctacctg caagcaacac gatcaatcct tgtaaataag cgaaaaatgg gccgtaaacg
    10201 gcattcacga tcctgccact ttgctggaat ccataaaggg aaggaaaata atggaaatcc
    10261 ccatatttaa tttgttgcgc ggcatcatag aaccgattgt aatggaatgg ggcatcagca
    10321 cccaaaatta gtttatgtgt gaataaatga ggcatgagaa atgccaaagc aatgaaaaaa
    10381 attgctaaaa atgggccata ttttttcaat tgtcgaactc ctttgcaaac tttagataaa
    10441 ttcatcatat atcctatgcg agaggtaggc aagaaattag aaaactcatg aaaatattta
    10501 tgaattttac aagaaaaaca taagtgaaag ttctaaggag agaggatgcg acataagttt
    10561 tgttgcatct ccttgttttg aaacagaatt tttcttaata ctcgaaacaa agtagctttt
    10621 tcatgacctc tcggtaaacg gtgttcaatc agctgcttct cggtaataag ctcactagcc
    10681 tagaaaatat gagaagctat tttctgacta gcgctcttat tactcaaagc ataacgcagt
    10741 tttcacaacc tcttccttaa acggtgttca aaagcttgca tctgcggtaa taagcccaac
    10801 ccaacaaaaa atatgagtag ctattttttt gggctgtact tattacttga tgcaggacag
    10861 ctttttcaca acctcatcgg ctttcatttt ctattttttt cctgaaccca tataataaaa
    10921 gaaagaacaa aaaaacttgc aagggaggac acatgtgaag cagagtaagc aaaaacagtc
    10981 tcgtcgactt ttgtttcgtt tgtttttatt aatatgtatc gtcgtagggt tactgatcgc
    11041 tttatatcca ttttatgtgg attctttaaa tagttttatt gatcaaaaac gtatcgaaca
    11101 agtacaaaaa cggaccgcag ctgaaattga agtgcagcga aagaaaatgg aggagaaaaa
    11161 ccaacgatta actgaccaag gattcaatcc tggtactgat cctttcaatg aaaagaacag
    11221 aaatgaaagt acaacatcca gtcaattaga ggaatggctg atcggaagta tcaatatacc
    11281 taagatccaa ttaaatattt cactttatga tcggctcaat ggtaggatcc ttgaaaatgg
    11341 agcaggcgtc ttgcaaggaa cctctttccc gcttggtgga aattcgacgc attcagtgat
    11401 ctctgctcac agcggtttac ctaatcgacg gttatttacc gaattagatc gtttagaaaa
    11461 cggagacacg tttattttga ctgttttggg ggagaaattg gcttatcaag ttaaaaatat
    11521 acaagtggta ctgccagatg acacgtctgt tctaacgatt tcagaaggag aagacttagt
    11581 taccttgctt acatgtacgc cgtatatgat caacacgcat cgtttgctag tgacaggaca
    11641 tcggattcct tataacgaat cggtaaaaaa agaagaagga aaaggaaatc aggaaagaac
    11701 catgcggcaa tggtttattc ttgcaggaac gataatagct gtagtcatac tgttagtgtt
    11761 tatcggacga ctaatctatc agtatagatt aagtaaaaaa gtgcttgatt tttcatttat
    11821 tattagtgat tcgtcaggga aaccggtaaa tggtagttca ttcattttga aacataagaa
    11881 aaaaacactt actagaaatg gtgtgccgtt ttcagtacaa agcgaccatc atgggaaagt
    11941 caagctggat caattgcctg gtggaactta tcgaatcgtt tcagctgatg atcctaaagt
    12001 tgctgtttct tttggtatta gaaaagtaaa acaagagaag atatactttt ttgaggggcg
    12061 aaaacttgta aaagagcttc aaaaaaatgg tttttatttt aaaatcaatg aataagtaag
    12121 gagagaaaaa atgatccgca caacaacaaa attgtctgcc aaagaactgg aatctgttct
    12181 atcgatttgg ctgcatgcta acttggattc tcatgaattc attccatcaa cttattggga
    12241 gaatcaagta gaatctgtta ggaaagcttt accagatgca gtgatttact tagcagaaat
    12301 agatcaagaa attattggtt ttgctggggt gattgatcag tttatcgcag gaatctttgt
    12361 gaaaagggaa taccggcaac aaagaatcgg tacgcaacta atgaaaaaaa taaaagaaac
    12421 caataaaaca ctgactttga cagtctatca aaaaaatcaa tcagctattc atttctatct
    12481 ttcacaaggt tttacaattc aaacacagca aaaagatgaa gcagtaaatg aggaggaact
    12541 tgtgatgaaa tggaatcaaa acgctgattt ttgatgaaca gaataacgaa ataatgctcc
    12601 cagcctaatt ttttgctggg agcattattt cattttgaag tcactaattt aactgtgtga
    12661 atatgcagtt gttacaatct ttgataaacg gtgttcaatc agctgaccct cggtattagc
    12721 tcaaaaaacg gcaaaatatg aggaactatt tttccatttg tttctctaat actcaggtca
    12781 aaacgctgat ttcacaacct cttgataaac ggtgttcaaa cggctgcttc tcggtaataa
    12841 gcccactagc ctagaaaata tgaaaagcta ttttctaact agcgttctta ttactcaaag
    12901 cataacgctg atttcacaac ctcttgataa acggtgttca atcagctgac cctcggtatt
    12961 agctcaaaaa acggcaaaac atgaggaact atttttccgt ttctttctct aatactcagg
    13021 tcagaacgct gatttcacaa cctctctttc acaaccttat tttactcgtt tataattttc
    13081 atcgaagtat tttccgctac ggatatcatc tggcattcca tcgtatggtt cttcgctaat
    13141 aacatcttca ttgtctatac ctgcatcacc catataagtg atcgtagcaa attcaggaac
    13201 aagtaatttt ggataagttt catatttttc acgagctgct tccatttctg cgatatgttc
    13261 gttttggaaa gtaacagtga tttctggatg ttcttcaacc catttaggga aaaagatcat
    13321 tccgtgaagt ttcttttcat ttggcataaa gtccaatgcc acgtctgtcc ctgttggctc
    13381 tgtccaagtg attttgaata cgccgtccgt caatttaacg atatcagctt cttggtcttt
    13441 tacccaacgg cctttgacca ttccgccatg gatacggtaa tcaacagtat ggtcattttt
    13501 ggcataccat tcatattccc aaccattgtc atacgtatag ataaagtgag ttccaataaa
    13561 atcttccaat tctttaaatt ctttcatgtt taagcatctc cttataaatt aaaacatgta
    13621 ataaactaca tgttttcgat tactcattta tgatagaatg gatttaaaga tttgtcaagg
    13681 agggaaaact gatggcaaga aaaaatacac ttcgatatat tttgttaggg ttattaagta
    13741 agaagaagat gacaggatat gaattgaatc aatcgttcaa aaatgaaata ggagaatttt
    13801 ggcaagcaaa acatagtcag atttatcctg aacttgcaaa aatggaagag caaggaatca
    13861 ttcagcatca agtagagatc acaggtgaaa aattggaaaa gaaagtttat gaattaacag
    13921 aagaagggaa ggaacaattg gcagagtgga ttcatacacc caccaatgaa ctaccggtta
    13981 atcgagacga atttgttctg aaattgtatt tcgtcaaaga cgtgaatgat ccggcattag
    14041 tagaaattat tcagcagcag cgtgaccttc atgaagaaaa acgacttcat ctattagagc
    14101 gaaaaaaaac gatctttcct actgaaaaag aaaaacatga aaattacgga cactacctga
    14161 ttttagcgca tgcgatcaat cgggaaacag aatatgcaaa ttggctaaca gatgtattag
    14221 aagaaagtaa ccgaaaaaaa taaaaaaata tccgaacagt gatggagaat tcctttctat
    14281 atgaaagaaa cgcagatcac cgttcggata ttcttatgtt caaacaggcc ttttttcaag
    14341 tatttatgta gcatctactt attaaaaagc ttggtactta ggagattagt ggcgtttaga
    14401 gttcttttaa caactgttcg tagtcagctt tttcatcgac aggaaggagc ttgtaagtta
    14461 attcgtctgt ctcgttgtca tgaatgatgt acatcttagc attctcttct ttgaagttac
    14521 cgatttgtaa aatcgtatag cgttcgtcga tcaattcgat atctttgatt gcttttgaaa
    14581 aaactttacg gacatggtgc attttctttt ggcggatttc tgccttttct gcagcttttg
    14641 acaaagtaaa tccgtcatct aaatattttt tgatcagttc tacttttatg actgtaggta
    14701 aacgatattt tctaggacaa ttcgcatcag cttcgatcga acgaatgaat cccttttgtt
    14761 cccaatacct taattgacgt ggagacacac ctacgatatc acttaattca ctgatgccaa
    14821 caaccaattg atcattttcc aacaaacgtt taagggaagc cccaaccatt tttgtcactc
    14881 cttttgtcct cttgcttccc ttaattatat ccgtattaac ttatgtgtca agtaggttga
    14941 caaatagcga atttaggact aaagtattct agtagtttca gaaaaaattc agaaagaagg
    15001 agaaatatga gtaacaacca acccgtagat atttacggaa aaccatataa tcggacactt
    15061 ttagttgttg tcttattaat tggtacattt tgtaccgttt tgaatcagac cttattgacg
    15121 acagcttttc ctacattgat gaaagctttc gatatttcag cgtctgatgt gcaatggtta
    15181 acgactggtt tcttgctagt caacgggatc atgatcccaa taacagcatg gctgatcaat
    15241 aaattcagtt caagaaattt atatctttct gccatgacga tctttttgat cggaacgatt
    15301 acttgcttta cagcacctaa ttttagtaca ttactaatcg gtcgtttgat ccaagcttgc
    15361 ggtgtgggag tatcgatgcc attattgcaa aatatcatgc tatctatttt cccgccagaa
    15421 aaaagaggat cagcaatggg gatgtcaggg atcgttattg gacttgctcc tgctttaggc
    15481 cctacattat ctggttatat cattgataac taccattggc gtgacttgtt tggtatggta
    15541 ctgccaatcg ttgttcttgt cttggtttta gcattcttcc taatgaaaag tgttattcca
    15601 ttgtcaaatc ctagcattga tattttatcc gctattttat caacgattgg attcggtagt
    15661 ttactttacg gattttctag tgtaggagat gacggctggg gaagcttgaa agtaattggt
    15721 ttcttagttg ttggtgtgat tttcatcgcc ttgttctcat ggcgtcaatt acatttggaa
    15781 catccattct tggaacttcg tgtattcaaa tcatctacat tcacgattgc agctgtttta
    15841 gctggtgtaa caaatatggc gatggtaggg gcagaaatgg tcgtaccatt gtatattcaa
    15901 aatattcgtg gagaatcagc attccattct ggcttgatgt tgttgccggg tgcattgatc
    15961 atgggggcta tgatgcctgt gacgggtgcg attttcgata aatacggcgc gaaacgttta
    16021 gccatcacag ggatgttcat tttgacagcg gcaactgcac catttgcttt cttgacaaaa
    16081 acgactccag ttttatatat cgtgatcctt tatgcgatcc gtatgtttgg gatctccatg
    16141 gtcatgatgc cggtaacgac ttctggtatg aatgcattgc caaataactt gatcagtcat
    16201 gggacagcgg taaataatac attccgtcaa atcgcaagct cgattggtac agctattttg
    16261 atcagtgtgt tgacgaatgt gacaaaagca aatatcccaa gcaaatctgt attggataat
    16321 acgccattag cttataaaga tcaggcaatc aatgccacac tgtcaggtta ccatgccgcg
    16381 tttatcgtag cgatcatctt tgggattctt ggctttatta ttgccttttt attgaagaaa
    16441 aaagaacctg ttctaatgaa agcgggggat aatgcatgat tattggagtt ttgattgtca
    16501 gcttgcttgc ttttgcttta acgaacgtgt tcgctaaaaa aacatggcaa acctttttat
    16561 ctttgatttt cggactaatc ttcgtcgctt cactaagttt gatcgtcgct aatttgtcca
    16621 atcactttgg aatggaaaaa gtaacggaaa caaaaacaga aaaaattgtt tccagtgctg
    16681 attcccaagg agcagatatg cttttgtata aagctttagg gaatggaaaa gaaaaagtgt
    16741 atctttaccg aacaaatgaa aaacaagaaa aaccaaaagc aactggtacg gataacgaaa
    16801 caaataaagt agaaaagaca gacggcgatg ctgaaaaagt gacgaaaact acttattggg
    16861 aatacaaaaa cgacatgtat aaattctggt tcaatattgc tgataacaat cacgaatatg
    16921 acagccgagt gaatacattc aaaatcccag agacatgggt agaattaagt acggaccaag
    16981 cagccaagtt agctgaatta gtgaagaaac agcaaagtac gatggaaagt gaagcaaaag
    17041 cttatgttca agacggtatg gtaaaagcaa tgactgaaaa tccaaaaatg agcaaagcag
    17101 agcaagaaca acgtacgaaa gccttagctg ctgaattcca acaacaagca ttcgcaaaat
    17161 tagtgaaaga agcaaaaggc gaataatatt ttgaacacca tgtaggaggt tgtgaaaaag
    17221 ctgctctgca tcaagcagta agaacaatca gataaaaata gcactccata tttttcatct
    17281 gattgggctt agtgccgtag atgcaagctt ttgaacaccg tttaaggaag aggttgtgag
    17341 cctgccgttt aactctgagt cacaaggagc aatttcaaaa aacagcttct catgtttgtt
    17401 gactattgtg acttgtgacc gaggagttgg caggagaaca ccgtttattc gaaaaaagga
    17461 actgcgacaa gacttttgtc acagttcctt cttttttttg ctatgctata ctagatgtaa
    17521 aaaataggag aaataaaatg agggaaattt attcttttga atcaaaaatc tatgcttccg
    17581 aagtcggcaa gggcggggca tatattattt ttccgtatga tataagaaaa gaattcggtg
    17641 ctggaagagt taaagtccaa gcaacttttg acaatgtgcc gtatgaaggc agtatcgtga
    17701 atatgggcgt gaaaaatcca gatggttcag tctgctacat ccttggacta cgaaaagata
    17761 ttcgtaaaaa catcggaaaa gaaatcggtg atattgtagc agttacagtg aagcaaaaat
    17821 aaaagaggtt gtgacaaaag acgtgtcaca acctcttgat aaacggtgtt caaaagccag
    17881 tttctcggta gtaagtcaaa tttatgcaaa aatgtggaaa cccatgttta caaaattttt
    17941 cttactactc gaaacgaagc ggctttatca caacctcttg ataaacggcg ttcaatcagc
    18001 tgtccctcgg tattagctca aaaacggcaa aatatgagaa gctatttttc catttttttc
    18061 tctcatactc aggtcataac gctgatttca caacctcttc tttcataatg gtttttcacc
    18121 atctttataa taaactggtt ctttgatatg gaaatctatt ttttccaacc aatctaaaat
    18181 cttgtaacct aactcttctg acatcggaaa agaggcgttg atttgtgcat tggagatatg
    18241 gtcaacatgg ataccggaag tgatcgtaca acttcccgga acggcagttt tgatgatcac
    18301 agctattttt tcggctaaga catcgtcttt atggaaccga ccatcgtggc tagggaaacg
    18361 tacagtttgc atctctgtat cacgagaaaa tgtagtgact gttccgatat gtggtgtatc
    18421 tccgcctgtt aaagtgatca ataagtcttt accgattact ttaacagcag cttggatcgt
    18481 gaaacctagt ttggttactt caactatcgt ttctttttcc atattaatca ccctgccaac
    18541 gttttgaatg ctcatttaca atttcaaatt gatccaaaag tttcattgta tggtgattaa
    18601 caagatcttg gatcgtttga ggctgattat aaaaagcagg aattggtggt atgatttgca
    18661 cacctagtcg tgctaattta gtcaagtttt ccaagtgaat ggcatttaat ggcgtttcac
    18721 gaggaacaat gactaacttt cgttgctcct tcattgttac atcagcagca cgtgcaatca
    18781 ggttgtcgcc taaaccaaca gagatacctg cgactgtttt catacttgcc ggtacgatga
    18841 tcattccatc ggtcaaaaat gatccgctgg cgacagcagc acctaaatct ttgtttgaat
    18901 aatggtaatc aaacaggctt tcgaattcag ttagtgataa gtcggattcc agctttaagt
    18961 tctgttttgc ccatggactg atgattccgt gtgtttctat catcggatat tcttttagtt
    19021 tcttcactag gttgatggca taaatggtgc ctgaagcgcc acttacacca atcacgattt
    19081 ttttcttccg ttgtgccaat tgttccattt tccgcactcc tttttatgat gtcaaaacag
    19141 ttgcagatca ttcattattt caaatatttt tcccaatctt ctacttcttg gaattttgca
    19201 cgtacaaaat gttctttcat atcgaaagga actgtaccgt caaagatagt ttttgcactt
    19261 atcccacgga aacgaataga gccaggatta tattctggta attctgatgg gtccaatgga
    19321 tggttcctca ttcctgggat cacgatgata tctttatctc cttggaaacg agtgttgaaa
    19381 gtccaaacta catcgttcat gtcgaaaata tcaacatctt catcgactaa aatgactgtc
    19441 ttcaattctt tgaaggctga taaagcaaga atagctgctt gacgctgaat accttcatcc
    19501 gcttcgtttt ctttacggat ttgcatgatg gtcatcaatt taccaccacc tgcaggagga
    19561 ttgtagacat ttactacttt tcctggaata gctttatcga ccaaggcaag aatacttgct
    19621 tctgtaggaa taccggccat agatacgtgt tcttcactgg gaccaatcgt tgtttgcatg
    19681 attggattgt cttttcggtg agtaactgct ttgactttca ctacttgtac agctggatta
    19741 gcatccccag tatagccagg aaattctggc attgcttttc ctgagttcgt gttgatatct
    19801 tcttgcattg tttcatttgg catgatttct gcttcaatga tgaattcagc acgagcaata
    19861 cccacttcat cgactgctat accatcaacg atttgaatag gttcgttacg caaagctcct
    19921 gcacaccata gttcattgta gccaagtgga gtggtaggtg gttcgaaagt cgtgccaatg
    19981 gcaattgctg gatctaaacc aatattgata gtgataggca ttggtttatt caaggcttcg
    20041 aattgttttt ggaagtgacc aatgtggcgt ccgccaggca tgatgtacat accgatcgta
    20101 tctttatctt ctagaaccat acgatggatc gttacatcgc tcattgtttt ttctggatct
    20161 gatcctaaga ctacacccat tgtgatgtat ggaccagcat cttcaggagt atttgtaggt
    20221 gcaggcaaaa tgttgcgaat atcgaagtct gcatcggtag ctagatgaac gacttcttgt
    20281 gctggagcgt ctgctttgtc tactttcaca ggtttgattg gattttctac agcgtctttc
    20341 aagaaacgac caagtgttcg ataatcatgg tgcaaaattt cacctacacg tttacgacta
    20401 gccattgttc cgatgttcac acgtgtgccg gggaaacctt tgatattgtt gaaagtcata
    20461 gctggtcctt cttgagtcgg acgttttact gtaccgccag caccgatata acggtaaaca
    20521 ccagataatt ctgcttcagg atcgatttca atatctgttt cgtgatattg acctggaagt
    20581 gtttttagtt cttcgatgac ttttcttaaa tcatacggtt gatctgtcat gagagattcc
    20641 tccttagttg tctttaccta tctatagtaa aaggtgaaaa agaggaaaac aattcaactt
    20701 gttcggtaaa gtattctaca atggaatgga tgcgtttttt tgataataga ataaactatg
    20761 atatacttat cactaaaaga aagcgcatac ttagtgttgg aggaaggaaa gtgaaaaaaa
    20821 tggaggagtc atttcctaaa gcagtaaaag tggaaaatat agcgaatatt ttgaaagtta
    20881 catttgaaaa cggagaagta aaatacgtga aatctcattg gacagaagag ataaccgatg
    20941 ccttgcaatt tggaaaaaaa ggaagaggaa aaagaaaaaa tcttctcgca ctttctcgta
    21001 atatgtggat tgggactgaa gtaacgattg aagcagatgg aacagtattc ataaatggaa
    21061 aagacaggta tacgccagaa gagttgtggt acaaaggaaa gaaaagtata ccagaattat
    21121 aaaaaataat taaaaaaaac agcgcgaaac aaggaacata ttacttcctc gtttcttgct
    21181 gttttctact atttcagcgc tcttatgact caaatctaaa tgtggttgtc acaaccttat
    21241 tctgcacgca aagcgatagc ggcgtctttt ttcgctgcca ttcgtgcagg aagatgaccg
    21301 ccaagcatcg tcaatatagt agagacgatc actagaataa tcgcatggac aggatttagt
    21361 tgagcaacat tttttagatc cgtcatgttg tataagatgc tattgatagg gaacgtagct
    21421 agccatgcaa taaacacacc taatatccca gaagaaatac ctaaaataca cgtttctgcg
    21481 tcaaatacgc gagtgatgtc ttttttacgt gcacctaaag cttttagtac accgatttct
    21541 tttgtccgtt caatcacaga tgtataagta atgatactga tcatgatcat acttgttact
    21601 aaagagatcc ctgcaaaagc aataaggaca taagtgatag catccatcaa tccgccagtc
    21661 agttcagtca tcgttccagc taaatcagta taaatgattt tatcttcatc tgatttgcct
    21721 ttattgtaat catctagata atccaagatc ttttctttgt cttcaaaatt gttcggataa
    21781 atcatgatac ttgaaggcaa gctgtctcca cctaaataac taagcaatgt ttgtttggca
    21841 ttttcgtcaa ctttttcagt agttaagaca tttacaccac tgtctctttg agctttgacg
    21901 atttctgatt ctttgttttc gttgacgatt tgagtcgtta attgatcgct ataagcgatt
    21961 cctggagata agagattcat tgtagaagaa gatttcacgc gtaggatccc cgagatcttc
    22021 aattcatcag aagcattctg atacatcgca tcataatctg tattagggat aaaattccca
    22081 gttggaagtt ttgtatagta agtattgttg tttactaatt tgaatgttgt accaacgata
    22141 tcatcaaaat caagtttttc gtcttctttc acatcaaatc caagattctt caatgcgttg
    22201 atattagtat tattattgcc gtctacgatc agcacgacat ctgttgctga ggctggataa
    22261 cttccggcaa gtaaagaata attgtctttt aaaaagtttt ctttgctagt gtcaagctgt
    22321 gtagggaaac ttgacactcc cacacctgtc atcgctgaca tcgtactaga taaagaaaga
    22381 gattccgtat caggattttg attcgagaag ctgacaggct gtactttgcc atttacatca
    22441 cgtaaaagat tgattcctgt agtacgggta aatccgatat tattacttaa gttaggatcg
    22501 atgtctgtta cgtaatcgac gtatgtttga tcaatcttat tcgtgtgctg tgctttatct
    22561 tcttcgctga cttttgcagt aatcgttttg ctgtctggat aatccgcttt gcttgcaccc
    22621 aatccggcat cgtcacgagt ctggttagtc gttaccttag aaatagtaat cggaaatttc
    22681 gccatcgttt cagcttgcgt gttatcgatt tgtttttgga atccagaaga aagggacaga
    22741 acgatcgcga ttccgatgat cccaatactg gaagcaaagg aggtcaagaa agtacgtcct
    22801 ttttttgttc ggatattgtt gaaggaaagc tttaacgctg tccaaaaact catctttgtt
    22861 ctgcgtaagt taaattgatc atcttttggt cgttcgatgt gaggatggga atctgttaag
    22921 atcttaccat cagaaaattc aatgattcga tctgcgtatt gatgggccag ttcaggatta
    22981 tgtgtgacca tgatcactaa tttttctttc gataactctt ggatcaattc catgatctgg
    23041 atacttgttt ctgtatctaa cgctccggtt ggttcatcgc acaaaaggat atctgggtca
    23101 ttggctagtg ctcgagcgat ggccactcgc tgcatttgtc caccagataa ctgatttggc
    23161 tttttatgca tatgatttgt caagccgact cggtgcaatg catcttctgc ccgttttcgt
    23221 ttttcgtctt tagaaacacc acttaatgtc atcccaagtt caacgttttc aataatgcct
    23281 agatgaccaa tcaagttgta actttgaaaa atgaaaccga tagagttgtt tcggtaggca
    23341 tcccagtcac tgtccttaaa gtctttagta gactttccgt tgattaccat atcaccggaa
    23401 tcataattat ctagtccacc aatcacattc agcatagtcg ttttaccaga accactagga
    23461 cctaaaatcg ctacgaattc tttttgtctg aaagcgacag acacaccatc caatgctttg
    23521 gtggtggttt cgccgacttt ataatatttt tttatatctt ttaattgaag cataatcacc
    23581 cttctcccgt attgaaatat tcggtatact aataagtata tcagaacaat gatcgtagta
    23641 tacgaaataa atgttaactg aagatgaact acaagaaaaa atctagaaat ttttcaaaaa
    23701 acagagggag atcaatgaat cgtattttag tagtagaaga tgatccgcaa ttacagttgc
    23761 tttaccgttc tgtgttggaa cgagcgggct tttcagtcat caccgcattg aatggagagg
    23821 atgcgctgaa aaaactagaa gcgacacgta tagaattaat cattacagat atcatgatgc
    23881 cgaaaatgga tggctatgac ttgctagact cattacgtag caccagattt gacacacctg
    23941 ttctaatgat tacggcaaag gccgattttg aggataagaa acgcgggttc aaattaggag
    24001 cagatgatta tatgacaaaa cccatcgatg tcaatgagat gatcctacgt gtggaagcat
    24061 tgcttcgacg ttcaaagatc aattacagca gtagcttgat aatcggacaa acaaaattag
    24121 agctagatgc ttatacagtg ttacaagatc agcattcgtt gattctgcct caaaaagaat
    24181 ttctgcttct gtataaatta ctgtcttatc ccaacaagat cttcactcgc caacagttga
    24241 tggatgatat ttggggatta gatacgaata cagaagaacg aacgatcgat gtacatatca
    24301 aacgtttaag gacccgtttt gaaaagacgg aagattttca aatcatcaca gtacggggac
    24361 taggctataa ggcggttatt taaagatgaa aaaaaagcta ttttcacaat tatggatcta
    24421 ttttgctagt attgtcttca tttcgatctt agtgacactg ctgtgttttc tcggttttat
    24481 tttcttattg tctcgacatt ctatctcgcc tgctgaatcg gctggaaaac caacgttata
    24541 cccgttattc gtctttgcgg ggttcagtat ggtcgtgggt acaggaatat cgatttttgt
    24601 tgggcggcgt atcctgcatc caatcagtgc gctagggaca aatatgagtc tggtagcaac
    24661 gggagatttt tcgattcgaa tggatgaaca gcagaaagta gcagaagtac agcaactgta
    24721 taaagatttc aacgttatgg tccaagaact caatagtatc gagacactga ggaatgactt
    24781 tgtgtccagt gtatcccatg aattcaaaac accactagca acaatccaag gatatgttca
    24841 attgttacaa gccccaaatc tctctgacga agaacgccaa atatttttat atcggattat
    24901 cgaaagtatc acgcagcttt cacaattaac agagaacatc ttaaaattga acaaactgga
    24961 aaaccagcgt atccaactgg aaaagaaaga gtatcgatta gatgaacaaa tcagagaagt
    25021 aatcgttttt tttcagccta aatgggagaa agaacagcta gaattggata tcgaacttgc
    25081 tgcagtaaat tacacaggca atgaagagtt tttgtaccaa gtgtggctga atatcatgga
    25141 taacgccata aagtacaatc aaatcaatgg acagattcat atcaaactat ttgagacagc
    25201 cacagagatt gtactggaag tgaccgattc aggtgtagga atgaatgaag agaccagaga
    25261 tcgaatgttt gaaaaatttt atcaaggaga tacaagtcgt caaatttctg ggaatgggct
    25321 aggactttca ctggttaaaa aaattctaga actgcatgat ggacgtattg attatagcag
    25381 tatcgaagga gtaggaacga cagcaatgat acggttaagt aaacaatagg aaaaagaata
    25441 aaacccctaa aaattctatt gaaggttttt aggggttttt agtcgttttt ttgtgattag
    25501 ggaaatgttc ttacggttct tttggcataa aaatcgctgc tttcttattg aactacgaga
    25561 aatgttagag gtgtcattga aacaaggaca tgatgcaaga aagagagcga aagtcatgcg
    25621 tcgctctctt tttttgggtg gatagatgga cagaaaatgt agggcttagt tttcttcttg
    25681 atttaaatac tcccaaaatg tatctgaagc caaagaatgc tcaccgactt tacgagtaaa
    25741 tgcaagataa ctctctgttg ttggagaaat agggagaatc acagtatttt cttttaatag
    25801 attcttgact gttttttcca taacaatagc aatccccatg tcatttgcaa tcatattgat
    25861 gatcaagtcg attcttgctc ctttataaga gatttttggt tcaaatccag cttcgcgaca
    25921 cagatctagt acaggttgat acaagttcgt agtggggcca aggagcaaaa agttctcctt
    25981 tttcagttcg cttagatcca atttcttttt actagctaaa ggatgatttt taggtagaac
    26041 tgctacaaaa tcgtctgatt cagtaggcaa ccactcaatc gaacttggtg gggcctggaa
    26101 acttctagca aagtggatcg tgtcactatg ttcattggcg tcattgtaag ttaattcgac
    26161 actttccact tctttcaact ggactgtaaa ttcaggatgg cgtttcaaaa actcggtgat
    26221 tttggaaaaa cctttataat tgatcattgt cggtatcgtt aagatattta atgaaagatt
    26281 gttgtctttc gtataggttt caagcacttc ttgcatagca tggtattgtt ctacgacatt
    26341 ttttacatat gggagcaata agcttccagc ttcggtcaat tcgatttttc tatgggcgcg
    26401 ttcgaataat ttgacgtcta attctgtttc taacgaaaga atctgtttag aaatatttcc
    26461 ttgggtggtg aattgtcgat cagcagtttt ggtgaaattc attgtttcgg ctaaatcaag
    26521 aaaaacttcg aatttatgga tatccatcat attcctccta cttattccaa taaagaatac
    26581 tttaacacaa aaaatgaatt ggtgtaatct tctctgtctg ttacaatctt tcttgcagcg
    26641 aaagcaataa ttacagaaat ttttctgatt tttttcgctt cgtagaaaaa gagaggagtt
    26701 ttttgatgcc aactggagtt ttgatcaatg taggttccgt tttgtttggc ggactaattg
    26761 gcggattagt aggaaataaa ttaagtgaac attttaaagc acagctgacg atggtttttg
    26821 gtgtgtgttc gatggggatg ggaatctatt ccattgcgcc gatgaaaaat atgccggctg
    26881 ttatttttgc tttagtgata ggaacagcga ttggtttgat tgttcattta ggtaatggga
    26941 taaataaggg ggctgcgctg atgcaagtac ctatttctaa aatcttccct agtgaaaagc
    27001 ttggtatgac ccacgatgaa tttatcagca cattagtgac ggtcattgtt ctattttgtg
    27061 caagtggtac ggggatctat ggaagtttag attctgggat gacaggagac agtacgattt
    27121 tgatttctaa atctgtcctt gattttttca cagcagctat ttttgcgtgt aatttagggt
    27181 atgtcgtttc tgtgatagca attccccaat tcattatttt ttatattttg ttcttattgg
    27241 caaaatttat ttatccattg actacaccag acatgatctt agattttaaa gcttgcggcg
    27301 gattcttgat ggtcgctacc ggttttagaa tgatcaacgt gaaaatgttc ccagtagctg
    27361 acatgatacc tgcaatgatc gttatcatgc cactgagctg gatgtggaca aattggatta
    27421 tgccactgtt ataataaaaa tcaaagagaa gccatttttt gctgactaaa aaggatcaaa
    27481 tcttttagtc agtttttttg tatttgacaa actgattttg aaactatatt atatgttgta
    27541 taatatagat tgaaataaaa tattacactt gagaatagaa ggtgacgtaa tgcacatcca
    27601 gattccaact gttcttcttg atggtactgt gttagcagca ttaagcaagg aagatatgta
    27661 tgggtatgcc ttaacaaaaa tcgtacaaga aagtctctct gtcagtgaat ctacactata
    27721 tccggttttg agaaggttga aaaaagaagg atatcttgag acctatgatg aaccttttga
    27781 aggcagaaac cgtcgatatt actcgttgac accaatggga agtcgtcatt tagaagaaat
    27841 tattgatgaa tggattgttt ttcgagattc tttagaccgg ttattggagg agagcacaaa
    27901 tgaatgaata tttgaatgaa gttgtggatc atcttcaaga aattcctgaa gacgatcgtt
    27961 ttgatttgat ccagtattat gaggaatatt ttttagattc tggaaaaaca ttagatcaga
    28021 tcattgatga atatggtaca ccaaagcagt ttgccttaaa attaaaaatc agttactttt
    28081 cagaagaaga acaagcagaa aacgagttag tgaaaaatcc aaaaagacaa attcgcctga
    28141 tttggttaat cattatcggt ttatttgctt ctcctgtcct cattccacta gcactggggt
    28201 ttatattggt tattggggga ctattggttg ctttactagc gctcattttt agtatctatg
    28261 ttttatgtat cagtatctta ggtgttggcc tattcatgat catctcagga atcagtgtgt
    28321 ttggacaatc gattctgagt ggattattct ttatcggtgt cggtctgttc gccacaggaa
    28381 gcgcagtatt tatttcgcca ctgttgctga aaggaacaaa agggcttttt tatgtcatga
    28441 tgaactttgt taaatggatg ggacgacgtt ttattacaaa aagagatctg cattcagcgg
    28501 gcgtttgaag gaggacacat aaattgagat tgaaacattt tttgattacc ggtattggtc
    28561 tgatgcttac tggtggcctc ctagcaggtg caacttatac attaggcgct caaaagagtc
    28621 tgacttggga taatggtcct cggttgatcg atatggttac tgagacaaaa aaaatcaagg
    28681 atgcaaacaa aatcgtcatc catgcagaaa atcaaacagt ttcggtcata cgcggattgg
    28741 attttgagat aaaaacgact tatgataaga cagaaaagcc agaaataaag gagaaaaatg
    28801 gcgtgttgac tgtgaatgca gtcaaaaaat caacaggtgc aatcattagt ttagaagaca
    28861 caagtgcaca aatcactatt gttgtccctg cagatcatga attatctgaa ttgacaatcg
    28921 aagggaataa tagtgcaatt gatatcaacg aagtatcaat caaaaaagtg aatactaaga
    28981 cacatgatgg ctgggtatcg ttcaatgaat ttacaggagg aacaataact gcgaaagatg
    29041 aattaggctc acttcgacta gatgaggcca atgtggataa cttgatcgtc acaggtgaaa
    29101 acagcaactt ccatctagaa gacagtttga tcagcaaaga aggaaaagtc atcctaaacg
    29161 gtggtaattt atctttgcat gagatggaaa acagtggcta tactatccaa acgtctggtg
    29221 aatcttatat tgaaaaagac taccagccaa taacaaatac tttgttagaa caaggacaga
    29281 aaaagctaaa gatcactgct aaagacacat cgatcaatat tacgacggat caagaggaca
    29341 atgaaacaga ttgatcctgt actcaactgg atattttaag aaaaaacagc aaagatcctt
    29401 ccaatctttg ctgtttttca tcgcttaacg cacataacta tagtaaaata agaaagaaaa
    29461 tatctaaaaa gaaaacaggg tgaaagagta tatgaaggta gaagaaggtc aaagagaaaa
    29521 gttaaagaca gaaatggaaa gattacatac ttatatcact caactaagcc aaaccttcta
    29581 tgatccagac aaagaaaaag tgatggttaa ttacccgaac aattcagaag gtcgccaatt
    29641 agagcaagtg taccatgaag ttttcaaaca tttattgacg gtgaagaaag agctggatta
    29701 ttattcttta ccgattatcg atacaggaat attgaagtat gatgggaaga aggaacgatt
    29761 tatctttaaa tctgttcggg aagatttgcc tctttcagca gggatggatc tagaggtctt
    29821 ggtagaagac tattttacag aagaaaagca ctgggttcga acaaaattgg attatttacc
    29881 gcaggcagcc ggagggacac aggcaagcgg ttggtacatc actgaagaca aagagttaga
    29941 actagaaggt gtaatggcgc gcattcgaaa aaaaattaaa aaagtaacat tagatattta
    30001 ttgaaggata aaggagcgca ggaagtagca tgagagaaaa aagagcattt tatatcaatg
    30061 gttatgcagg gattgtcgga ttggtcgtat tagctttagt tggattgttt ttcttctatt
    30121 taggcatgtg gcaagcgaaa gtttgggcac tttttttaag tatttttctt tggttgatca
    30181 cgttattgtt gttaagttcg gcaactgtag tcagtcctaa tcaagcaaaa gtaattttgt
    30241 tttttggaca atatttaggt acgattcgag aaaatggctt tttccttacg atacctttgg
    30301 cacaaaaaat gactgtttcg ttgaaagttc ggaatttcaa tagttctgtt ttaaaagtca
    30361 atgatttgga tggaaacccc atcgaaatct cagcagtagt agtctttaaa gtcgttgata
    30421 cagcaaaggc attattcgat gtagcgtatt atcaagattt tgtagaaatc caaagtgaga
    30481 cagccattcg gcatatcgct agccaatacc cgtatgatac attcaatgag aatgatttga
    30541 cgcttcgagg aaacacgacg gcagtgtctg acgagttgca aaaagagctg caagagcgtt
    30601 tagcagtagc aggtgtcgaa gtaatcgaaa cacgcttgaa ccatttagcc tatgcaacag
    30661 aaatcgctag tgccatgctc caacgtcaac aagcaaaagc cattttgtct gctcgacaaa
    30721 ccattgttga aggagctgtc acaatcactc aaatggcctt agagcaaatc gaagatggac
    30781 aagaaatcaa tttcaccgat gatcggaaag tccaattgat caataattta cttgtctcaa
    30841 tcattacaga caaaggaacg caacctgtta tcaatacagg cgacatgaaa gaccgtaagt
    30901 gacatacttt ttgtaagata ggaagaagga gtttaggacg gattattgtc ttgaactctt
    30961 tttttagttg ttttaaagaa aatgacaaaa ttgaaagaag aatgatagtt gattcgaagg
    31021 cagaattgtt cgcttttttc tataatcagt atataaagta agagagaagg ggaaaaagtg
    31081 aaaaaacttc tgatcggtct acttgttttc atcgttgtgg tacttgcagg ggtgaaaatc
    31141 gcagattacg tagttatggg tggagaagaa tactatgtac aaattacgac agatggtaca
    31201 aaaacagttt caaaatcaga ctctggacaa gaaacagtca actatagata tatcctgcct
    31261 ggctatacga aagagggtaa ggaaaaagaa ctggacttca agggacaatt gactcgaccg
    31321 cttcgtaaag gagcatattt aaaaatcacc tggaacaaaa ataaaggtgt cacttcgtat
    31381 gaagaagtcg aaaaaaaaga cgttccgaaa acagcactgg aaaaactaat taaagggtag
    31441 ggaaagaaat gaacaaaata gtcgaagtac agaatgtaac aaaagtatac ggaaaaaaca
    31501 atgagaaaaa gacgcaagca ttaagcggca tcagcttcga tgtagaaaaa ggcgaattta
    31561 ttgggatcat gggcgcttct ggttctggta aatcgacact tttgaatatt ttatccacat
    31621 tagataaacc aacagatggg catatccgaa tcaatcaaaa agatgtgacc acattaaaag
    31681 gaaatcaact agcagatttt cgtgcgaatg agattggctt tattttccaa gacttcaatt
    31741 tattagaaag cttgacagca caagaaaata tcgctgttcc tctttcttta caaggcgtca
    31801 aaccaaaaga aatcaagcaa cgtgtccaaa aaattgcaga acgtttatcc atctctcata
    31861 ttttggaaag ctatccttct gagatttctg gtggacaaaa acaacgggtc gccgccgcac
    31921 gtgcattgat cacacaacca acgattctat taggggatga gcctacaggt gcgctggatt
    31981 ccaaaagtgc ccgggatctt ttagatacga tggacgaatt gaatacaaaa gatcatgtat
    32041 cgattcttct tgtgacgcat gatccgtttt ctgcaagtta ttgccaacgt attttattca
    32101 tcaaggatgg cggtatccat caagaagtga aacgtggaga tcaaagccgt gattccttct
    32161 atcgagaaat actatctatt cttggaaact tggaacagta gggggagatt gactatgctt
    32221 tggaaattat cacttactgg gatcaagagc cgtttaagag actacctggt gttattctca
    32281 ggattagtta tggcatctgc tattttttac atgtttgaat caatggcaag caacgaagct
    32341 tttttgaaaa gtaatacgat cgttgcggct acagttatca ttttccgatt cggttctgtt
    32401 ttactaggga tcatcacatt cgtttatatt ttatatgcaa attccttttt gatgacgatg
    32461 cggcaaaaag actatgcaat gtttatgatg ctaggagcaa aaggcagaaa aatcgcacag
    32521 atgatttttt ctgaaacatt cttagtaggg atcgcagcta ctttagtggg ttcagctgtc
    32581 ggtgtaggat tgacaagtat cgtccaccga ttattagtgg atcagttaga tctcaatatt
    32641 tcgcatttta caccttttag tattcacggg ttgttgatca ctgttttgtt ttttgctgtt
    32701 ttgtttttat tagctgctgt tgtcaatgct ttttcgattg tcaaaaaacc gatattagca
    32761 ttgattcgtg cggatcagac accaacaaga atcaagcagc ataaattctt gtttttcctt
    32821 gaagtagtac tgggaattgc ttttctaggc tgcggttact atatgatgaa acacgtgggg
    32881 acctatcaag tctttggtat aggagtagcc ttagttacga tcgtattagg aacttatttc
    32941 attttccatt ctgtgatcat tttcttttta tcattactaa agaaatcaga acagatttca
    33001 ttgaaaaaat tgaacaattt cacattgtca cagttaaact ttcgtattcg tgaatataca
    33061 caaatgctct caatggtcgc tatgctgttt gccttggcac tgggcgcttt gacggtagga
    33121 ttaggtttta aaaatgaaat tgcagacttg acagaaaaca attctggata tgatctagtg
    33181 atgaataatc ctcgggcaga agatcagcaa aaaatcaaag aactttcacc aacactttct
    33241 gcttcttata ctcaaaaaga agatgcggga acgatttact ataatgcaag tgaatttgcg
    33301 gctcaaccat tgatcatgat aaaacatgaa gatggaacac cgccgaagat cacgaaagaa
    33361 aaagttcctg ctgaaaaaat gaatgaactg actgtacaag aggaacttcg aagctatgaa
    33421 ttgccggaac agcaagaaaa agaaatcaag gtagtcagtc aatcagaatt tgatcaactg
    33481 aacttgccac aatccacttt acagctagtt caggtaaaag acttccaagc aaacctgaaa
    33541 ccaatcgaaa cacttgttgc tcaaaataaa atgaacaatc catctttgca aaaagtagag
    33601 tacagcaacc agaaatatga aatgtatgaa gtgtataatg gtctattctc tggttttgaa
    33661 tttatgggat tcttcctagg tttagctttc ttgaccatgc ttgctagctg tttgatgttc
    33721 aagatcttgt caggaagcaa gagtgacatt gctcgttatg aaatgcttga aaagatagga
    33781 acacgacgcg ggttgcttaa acaatcgatc cgtagagaag taggcgtgtt attcttagca
    33841 ccaggaatct taggtgtagt ccatgtctta ttcggattac aaatgtttgg tctattcatg
    33901 caaaatccat acaaagatat ttgggttccg tttacgatct tcttcgtatt gtatttcatc
    33961 tactatgtac tgacgacatg gttatatact ggaatcgtat tgaaaaagag attgtgaaaa
    34021 agctgtcctg catcaagtaa taagaacagc caagcaaaaa tagctcctcc tatttttcgt
    34081 ttggttgggc ttattaccgc agatgcaagc ttttgaacac cgtttgttcg gaaaaagagg
    34141 ttgtgacaat atttttgtca caaccttttt ttcacggtct tttattagaa tatagtaaat
    34201 tttttctcgt tactcacgga ataagctgtt aagaaaacgg tttccatgta tactggaatc
    34261 agtgcaaatg aaagaaaaga gggtgcaagg aacatggaaa tcaatgaaca aaattttggc
    34321 gaaaactatc acttgattac gatcacgaat caaaatggga catctttgtc tgtcagtgat
    34381 cttggggcac gggttgttca ttttcaaaca ataatcgata atgaaaaacg agagttgatc
    34441 ttaggttttg atgaagcaaa agaatatcta gaaaaagacc cttatatcgg tgcttcaatc
    34501 ggacgtatgg ctggacggat tacgaatggc acattcaaat tagatgatga aacgttcgaa
    34561 gtaaaaacag acccggacac tggtcattgt ttacatggtg gtgcacctag ctttgaagcc
    34621 aagcagtggc attatacagt catcaatggt gaaaacgaag catcggtcat tttctatcag
    34681 actagcccag acatggaaaa cggatttcct ggaactttag atgtagaagt acggtatacg
    34741 ctgacgaacg atgatacatg gcgagtgacg gtccaaggga tcagtgaccg caaaacagta
    34801 ttcaatccta caaatcatgt ctatttcaat ttaaccggtg atccagcaca gtcaatcgac
    34861 gaacatatac tttggttgaa tagccgatta tttgctacgc tcaataaaga tacaacgcct
    34921 acaggagaag tagtttcagt aagtggcaca gcatttgact tccaacgtcc taaaaaatta
    34981 ggtgaggtct ttgccagtga ttttcgccaa tcaatgatag tgggcggtat cgatcatcca
    35041 tttttgttga aaaaacaatc tggtttacta aatgctgcgg aattgacaag cccagatgaa
    35101 aaagtatcga tccaagtaaa aacagatgct tcaggaatcg tgatttttac agcaaatttt
    35161 ggagaagatg gaccggaaat gcgcgggaat aaattagtaa atcatggcgg tatcacattt
    35221 gagactcaag aactgccagg agcggagcga cttgaaagtt ttggagatgt cactctggaa
    35281 cctaaccaag tacgcgagtt tgtaacggaa tacaaaataa atataaagaa atagaataaa
    35341 ttaaaaaggg agtgtgacag tgtcacatcc cctttttaat t
//
LOCUS       DAXQKX010000024        34590 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.024, whole genome shotgun sequence.
ACCESSION   DAXQKX010000024 DAXQKX010000000
VERSION     DAXQKX010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34590
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.024"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            212..604
                     /locus_tag="ACF3MF_001319"
     CDS             212..604
                     /locus_tag="ACF3MF_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFE3927324.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="ACF3MF_001320"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="ACF3MF_001320"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HFE3927325.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            2698..2943
                     /locus_tag="ACF3MF_001321"
     CDS             2698..2943
                     /locus_tag="ACF3MF_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927326.1"
                     /translation="MKEKDCFYDKLYKLLLQVGKSSSLLGGILSIIMFVLFFYLLFHL
                     KFFSNDFLICLGLTLAMFISSLLCGLNFFCTHKGLKK"
     gene            3165..4775
                     /locus_tag="ACF3MF_001322"
     CDS             3165..4775
                     /locus_tag="ACF3MF_001322"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HFE3927327.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            complement(4752..4964)
                     /locus_tag="ACF3MF_001323"
     CDS             complement(4752..4964)
                     /locus_tag="ACF3MF_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927328.1"
                     /translation="MKMKIFKKFFAKNKISNSALIEKSLLLSIFFPTNNNKSEKEKSD
                     KKIAYPLLLLLFSFYQVQKLFCFVIC"
     gene            5067..5936
                     /locus_tag="ACF3MF_001324"
     CDS             5067..5936
                     /locus_tag="ACF3MF_001324"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HFE3927329.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="ACF3MF_001325"
     CDS             6101..7372
                     /locus_tag="ACF3MF_001325"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFE3927330.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /gene="rho"
                     /locus_tag="ACF3MF_001326"
     CDS             7369..8664
                     /gene="rho"
                     /locus_tag="ACF3MF_001326"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008186 - ATP-dependent activity, acting
                     on RNA [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HFE3927331.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="ACF3MF_001327"
     CDS             8763..9026
                     /locus_tag="ACF3MF_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HFE3927332.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="ACF3MF_001328"
     CDS             9471..9920
                     /locus_tag="ACF3MF_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFE3927333.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="ACF3MF_001329"
     CDS             9977..11395
                     /locus_tag="ACF3MF_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFE3927334.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVLALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSISTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="ACF3MF_001330"
     CDS             11395..12255
                     /locus_tag="ACF3MF_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HFE3927335.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="ACF3MF_001331"
     CDS             12429..13202
                     /locus_tag="ACF3MF_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFE3927336.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="ACF3MF_001332"
     CDS             13349..13714
                     /locus_tag="ACF3MF_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HFE3927337.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="ACF3MF_001333"
     CDS             complement(13862..15070)
                     /locus_tag="ACF3MF_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFE3927338.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="ACF3MF_001334"
     CDS             complement(15089..15367)
                     /locus_tag="ACF3MF_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927339.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15560..16216
                     /locus_tag="ACF3MF_001335"
     CDS             15560..16216
                     /locus_tag="ACF3MF_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFE3927340.1"
                     /translation="MDSRVLKEYLDKNDFPIIRKGYHKYLTFEGMEDSHTYILKEGTV
                     KASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESEYAEFYRINRVRFW
                     QNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLYELYDLFGVRTEEG
                     MLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIVILNMDLLEDNIIF
                     "
     gene            complement(16658..17455)
                     /locus_tag="ACF3MF_001336"
     CDS             complement(16658..17455)
                     /locus_tag="ACF3MF_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HFE3927341.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="ACF3MF_001337"
     CDS             complement(17452..18636)
                     /locus_tag="ACF3MF_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HFE3927342.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="ACF3MF_001338"
     CDS             complement(18661..19908)
                     /locus_tag="ACF3MF_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFE3927343.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="ACF3MF_001339"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="ACF3MF_001339"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HFE3927344.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="ACF3MF_001340"
     CDS             21888..22202
                     /locus_tag="ACF3MF_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HFE3927345.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="ACF3MF_001341"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="ACF3MF_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HFE3927346.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /gene="tmk"
                     /locus_tag="ACF3MF_001342"
     CDS             22887..23531
                     /gene="tmk"
                     /locus_tag="ACF3MF_001342"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HFE3927347.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="ACF3MF_001343"
     CDS             23546..23875
                     /locus_tag="ACF3MF_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HFE3927348.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="ACF3MF_001344"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="ACF3MF_001344"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HFE3927349.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="ACF3MF_001345"
     CDS             24863..25687
                     /locus_tag="ACF3MF_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HFE3927350.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="ACF3MF_001346"
     CDS             25680..26027
                     /locus_tag="ACF3MF_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HFE3927351.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="ACF3MF_001347"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="ACF3MF_001347"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HFE3927352.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="ACF3MF_001348"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="ACF3MF_001348"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HFE3927353.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="ACF3MF_001349"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="ACF3MF_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HFE3927354.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="ACF3MF_001350"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="ACF3MF_001350"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HFE3927355.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31684..32451
                     /locus_tag="ACF3MF_001351"
     CDS             31684..32451
                     /locus_tag="ACF3MF_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3927356.1"
                     /translation="MEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGEFVGIMGPSG
                     AGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQEFNLIDTLN
                     AKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQRIAAARALV
                     VQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTASYCDRILFIK
                     DGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="ACF3MF_001352"
     CDS             32441..34483
                     /locus_tag="ACF3MF_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFE3927357.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
BASE COUNT        11120 a         6128 c         7258 g        10084 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcttgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgattt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt agtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtat ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcggaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga
    34561 tttttgtcac aacctcttta ttttttatat
//
LOCUS       DAXQKX010000025        34537 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.025, whole genome shotgun sequence.
ACCESSION   DAXQKX010000025 DAXQKX010000000
VERSION     DAXQKX010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34537
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.025"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..932)
                     /locus_tag="ACF3MF_001353"
     CDS             complement(<1..932)
                     /locus_tag="ACF3MF_001353"
                     /inference="COORDINATES: protein motif:HMM:NF039657.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbL family protein"
                     /protein_id="HFE3927358.1"
                     /translation="MDVIDQIKETGSDILSSAGDAISGIFEGVKESVDSVLHPIDSLL
                     GSWGSDLLEASMKIANKTTFDIPNIKLISTITNVFVFATTTFAICIVLYKVIEAQIQA
                     SNGSGDALTANIVQKLFYSSIALATLPWAMNFFIKKIVAPIGEYVIQQVANDLNVETI
                     GERLRNFLVSNFFNGGVSAVVLFVFVIFFAFSIAKYFVAICVFYADFLVLTMLTPLVA
                     LSLLTDEQNYFQIWIKELLSEALTMLIKLILYLLMITLMIAEKYTLPNFMLMVGCGLL
                     IIKTPSALQNMWYSTKVSKGGGLGNLAMMAMFRK"
     gene            complement(934..1857)
                     /locus_tag="ACF3MF_001354"
     CDS             complement(934..1857)
                     /locus_tag="ACF3MF_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927359.1"
                     /translation="MNGLKEFFGNIPMFQKQVEREIEEKGIKPSEGIKKMEFSRQVLR
                     NIVIGVLFIGILAFVGISYFNNKNQPPVAPTATTTSKESNQSEASGEATENSSQAVQG
                     SSDHLLKLSAKERADEATEAFESWYKSFSKGDVILEINKELLKEGSGGTSPIELQTKL
                     IDNLKAKFGDKVSDDFYSGLQASFNFNPVIVDGTKGLTISKQNDDQSQWLRTWFLDTE
                     KTAQNTKIILRNDFSYEWADWRNKGQHDEKVGSMFTQIDWANDLRYEVIGIVTSKQEK
                     NIENIGGVFVVMQYNEKIGKWQVSGTIGGVM"
     gene            complement(1875..3530)
                     /locus_tag="ACF3MF_001355"
     CDS             complement(1875..3530)
                     /locus_tag="ACF3MF_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
                     /protein_id="HFE3927360.1"
                     /translation="MSSLLAESDGLILGKFQSGNVVIQPEDSKISNRNIFVVGGPGSF
                     KTQSYVLPNVVNNRSTSIVVTDPKGEIYELTNEIKKAQGFKTVVINFKDFLLSSRYNP
                     LLYIRKSNDTNKIANVIVSAKNDPKRKDFWFNAQLNLLNTLIKYVYFEYEPSARTIEG
                     ILDFLEEFDPRYNEEGVSELDEQFERLPDGHEAKRSYYLGFRQAQSEARPNIVISLLT
                     TLQDFVDKEVAEFTSTNDFFFEELGTSKICLYVLISPLDRTWDGLVNLFFQQMFTELY
                     FLGDKHNAKLPVPLVMLLDEFVNLGYFPTYENFLATCRGYRISVSTILQSLPQGFELY
                     GDKKFKAIIGNHAIKICLGGVEETTAEYFSRQVNDTTIKVYTGGTSESKTSAKTTNRS
                     GSKSESYGYQKRRLITEGEVINLQQEENGRKSIVLIDGKPYMLRKTPQFELFGNLLKK
                     HEISQQDYISSQTEFAKEYIEELEVQHKQRKVQLASAPVFHEKKQENDLNKKEIKLPE
                     QPIESEVTEEVEEKEQLMSDILSSFDEGIEENTTNNDNSELPF"
     gene            complement(3523..3954)
                     /locus_tag="ACF3MF_001356"
     CDS             complement(3523..3954)
                     /locus_tag="ACF3MF_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927361.1"
                     /translation="MAKKKQEQVKLIILVILYLLLLPVTLIVFKLLPFIIANDTNIEL
                     STFVTTILKHPINTFLEIIQSNYMIPFFIVQIIVLIILFVFLHPTKRQPFEVVGKTNP
                     VHGSAYWGEESEINAPKNVHLIPEKSMKKILEKSMRRGKNE"
     gene            complement(3959..4510)
                     /locus_tag="ACF3MF_001357"
     CDS             complement(3959..4510)
                     /locus_tag="ACF3MF_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927362.1"
                     /translation="MEFDKIKVSLFISTLALLVVTIGMIVFGIKQGEQIRHLKSDLKS
                     VQTELADKQAEQNTNQSESEKIIKEFYKTVYNYEKSQKEISMTTVKELATDNVYQELQ
                     NEINVNNSYSPQQNTIQKSSVNENEIKILAYASKDNSQQYLVTAPIHQVFNGTKNDFE
                     INQIIQIKNQQITQRTTIQLGEE"
     gene            complement(4523..5632)
                     /locus_tag="ACF3MF_001358"
     CDS             complement(4523..5632)
                     /locus_tag="ACF3MF_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HFE3927363.1"
                     /translation="MGATAAKLLIRYRKPIAKAILGFFVFIIVIFLLIFNNDQTAPSG
                     GLATENKNLSESVLRYKSTVEKYARQYDGMEYVPYILALMQIESGGNGGDPMQSSESL
                     GLPPNTIQDPERSIQRGVEFFVENMKSAINRGSDIKTALQAYNYGGGFVDFVVKNGGT
                     YSFELAKQFSINMSGGEKVPYVNALSTSMGYNYRYNYGNMFYVPKLLEYVNESQASAE
                     GVQNNSNNTGAVQVDVPSEYKNKLRYPRYDGHNYNTSGSYPFGQCTWYAFNRMAQIGK
                     PVDDFMGNGGEWGYKGKALGYKVTNKPKVGTAISFPPGSFGSDPVYGHVAFVEVVNAD
                     GTLLVSECNVVNPGSGTISYRVVPASIANIASYVE"
     gene            complement(5654..7006)
                     /locus_tag="ACF3MF_001359"
     CDS             complement(5654..7006)
                     /locus_tag="ACF3MF_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000875579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraF"
                     /protein_id="HFE3927364.1"
                     /translation="MKYKILKNLQFYYQENVIVVQINEKYLTNREHIFDVEESEQYFV
                     DVEEILTKDGKLEIVYHRPNGYTPLLDLKEYADFYKLDIVNRLLEMNVLEKTNTYLAM
                     QNILLKDTRDLLFIYKADHFGNLPYSTKEELEQWKNFICSFFGKFSLEKYEKNRIEIL
                     TKEKNSFLNDVEAVESLESLRDLIKNRLTEEQKNFFSAELQDKKANVRKIRRNKSLKI
                     ALVVGVIALYGGTVFLMKVNEKKQVTATQQSAETEITILNKIIDNDSENIEEDMQKLN
                     YPKKKQVDIYVKLGDYTKAYELDKKSDKKIIQSLYKQGETEKIENLDLPGSDYLADFK
                     KILAYDNSTDIEYLVQTSTDTTIVEALIDQAVKKKDIPTVKNIRQVSITQKKLAIDPK
                     RQISMIDLLIENNSEELENIYKDNSLNDDLKKKQTNDLLEENNTLLSEKIELTNAEKD
                     "
     gene            complement(7020..8981)
                     /locus_tag="ACF3MF_001360"
     CDS             complement(7020..8981)
                     /locus_tag="ACF3MF_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002425003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4 family type IV secretion system protein"
                     /protein_id="HFE3927365.1"
                     /translation="MEKIPKEKIIVIPEVDTDVVSDLAPFNFTVERDKLLIDDSYAVP
                     YVITKYNNKPRGNWFNRIRKMSGDITISHYYTKANGNSLNDYYNRTIKNKQAEIDRSH
                     DPLTIIRLEREMKIAQTQLEQAVDENTSYLYLYTYVLIKSKSEDKLKKLCEDFETRCI
                     ASGVKALIPYTMIDKAYWSALPLQSNEVPEYTYTIANSISASSIFPFDDNELSVFTKN
                     MIIEGINKDTENIVSIDYTNRKLVVNRNKFVFGLSGGGKTTYLTSDYLKKYAFADNST
                     ELKHRIVLFDPEDEQTERVRSLGGEIINLSSMSDVRINPFQIYSRNTPDVDLKESLSD
                     FEEDELVENLEIKHKDFEMTENDIDKEISKRMNILTPYFLMVDHSLTDSQLSIIKLEA
                     KKCYTTLYEKKNLSKMENTDFPTFSDLESRLKALEETDPKRYKRIEDFIYSLEDFTIG
                     SRTIFNGHTNIDLSNPLICFSLRDLQTEEGIRDLAYLNSFSYLFEEITNNPQIVTSVY
                     ADEFHFLLKNKISADFFFQAYKRFRKYNADCTVSTQQIDDVLKAPDNIGKAIIGNSFT
                     KVFFGLDETEAQGISNELKLKLTKKELSFITSKRQGEALLFHGTKRAKIKVDLTQEEM
                     RLLNPGGYEDIYGVSPKKEINWLLRSKIQ"
     gene            complement(8992..9621)
                     /locus_tag="ACF3MF_001361"
     CDS             complement(8992..9621)
                     /locus_tag="ACF3MF_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927366.1"
                     /translation="MFDFLKKSSKSNDNKKSDTIKEMIYWEDSSRFQGVFKDFFVVYQ
                     PEKKQFSLVSMLKVDGLNVDTLPVSEQEGLNEDFGVFLSQNVLYEPQITSKNVPVEID
                     DFVEAWGNTVENYRKMPGHNEALLQLKASYYYHYRNLASNMETSKKQHFVINSEPISK
                     ETYDSLELSYQVLRDKTRTIRTALIAFLSKYDCQVEICTIGEMKKVLNS"
     gene            complement(9638..10021)
                     /locus_tag="ACF3MF_001362"
     CDS             complement(9638..10021)
                     /locus_tag="ACF3MF_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFE3927367.1"
                     /translation="MNSDQVKQALLDLLNADTEKGRTWFFPSNVSDRYTVILGLDLKQ
                     SAKAIGTALISVLLAILIFRSTAVFPLIIYVIVGLVSFGGVWAFYTIKPITDRPNISI
                     SDFMKQRKDFSKRPKVYYKKPKERV"
     gene            complement(10040..10372)
                     /locus_tag="ACF3MF_001363"
     CDS             complement(10040..10372)
                     /locus_tag="ACF3MF_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CagC family type IV secretion system protein"
                     /protein_id="HFE3927368.1"
                     /translation="MKKFIKDTKFKLGSAVVALGTLFITDPVFAATDPQAKLVQAGNT
                     IKGVLTALIVVVGGIACAKIVIKYLPSIDDPQEKNTMYKALGTALLVTALGGALVWLV
                     PWAYGLLA"
     gene            complement(10396..12381)
                     /gene="mobQ"
                     /locus_tag="ACF3MF_001364"
     CDS             complement(10396..12381)
                     /gene="mobQ"
                     /locus_tag="ACF3MF_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobQ family relaxase"
                     /protein_id="HFE3927369.1"
                     /translation="MAIFHLSMTIAKREGGKRSLIAMASYRSGEKLYSELYEKTNLYN
                     HRTVKPEAFILKPDYVPNEFLDRQTLWNKMELAEKQVNSQLCREVNVALPIELNNTDQ
                     RSLIEEFVKDNFVSEGMIADVAIHRDDENNPHAHIMLTMREVDSEGNILNKRKKIPKL
                     DENGNPILLENGKIKMVSIKTNDWDRKSLVSEIRKDWADKVNQYLKDRNIDQQITEKS
                     HAELGKKELPTIHEGFYSKKLEEKGVISELKRKNLEIQSYNDILAELDKLESQEKVLK
                     QDQNFTLKFEKTFSPLEKGELKNLSKEFKLFINDENIDKRLGELKRWENSLIFNNKME
                     IQKQRLMLSKISSERDMLTKANEILDKQAERFFKKSYPSLNIDKFSNHEVRAMVNETI
                     FRKQLLNKDQLAEVIYNERVVEKEESKKIFKEKPFQTSRYLDSKIKQVEDSITKENNP
                     ERKEILSIKKEKLIGIKQGLIEYVQSEVERKFDKNVSIDSVIEGEMLLAKADYYKTTD
                     FSKVEGVARFSSEEINSMLEQSKGFLTNIQTVKIPNDCQGVFFVQDSMKHIDELSPLA
                     KQNLKKVVNRNAYLPDSDKIELSKEIENTNKDQSQELDKDVPEKNEVTVKMFQFAKSI
                     NRLLSGNQLQKKRNLDKLIKQTKAKENQSLQRNIPLR"
     gene            12673..12972
                     /locus_tag="ACF3MF_001365"
     CDS             12673..12972
                     /locus_tag="ACF3MF_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927370.1"
                     /translation="MENQDQNINAINGNFNSKTKPKKRKKKTVSDIELQIKELQKKKE
                     ELILKSKADIGDFVLSTLSKLDISIESIEENKELFYDELETLLNANSQNFSELLK"
     gene            12975..13232
                     /locus_tag="ACF3MF_001366"
     CDS             12975..13232
                     /locus_tag="ACF3MF_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927371.1"
                     /translation="MANNDLNDINKRIEKLKIQKNILRANSEQNINRKRRTKRLIEKG
                     ALLEKYFEIDYLTVEETEEFLKIFSEYIKANKPKKYQKKEK"
     gene            complement(13255..13488)
                     /locus_tag="ACF3MF_001367"
     CDS             complement(13255..13488)
                     /locus_tag="ACF3MF_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927372.1"
                     /translation="MRGINNHQKYDFDLYQIEARSPMSTREITLTVDFIEKKVSGDII
                     AFGDWYDLDIESVNEILKQLKKEGQTLRTINFI"
     gene            13758..14150
                     /gene="merR"
                     /locus_tag="ACF3MF_001368"
     CDS             13758..14150
                     /gene="merR"
                     /locus_tag="ACF3MF_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0045340 - mercury ion binding [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0046689 - response to mercury ion [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hg(II)-responsive transcriptional regulator"
                     /protein_id="HFE3927373.1"
                     /translation="MIYRISEFADKCGVNKETIRYYERKNLLQEPHRTEAGYRIYSYD
                     DVKRVGFIKRIQELSFSLSEIYKLLGVVDKDEVRCQDMFEFVSKKQKEVQKQIEDLKR
                     IETMLDDLKQRCPDEKQLHSCPIIETLT"
     gene            14175..15815
                     /gene="merA"
                     /locus_tag="ACF3MF_001369"
     CDS             14175..15815
                     /gene="merA"
                     /locus_tag="ACF3MF_001369"
                     /EC_number="1.16.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016152 - mercury (II) reductase (NADP+)
                     activity [Evidence IEA];
                     GO_function: GO:0045340 - mercury ion binding [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0046689 - response to mercury ion [Evidence
                     IEA];
                     GO_process: GO:0050787 - detoxification of mercury ion
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mercury(II) reductase"
                     /protein_id="HFE3927374.1"
                     /translation="MNKFKVNIQGMTCTGCEKHVESALEKIGAKNIESNFRRGEAVFE
                     LPDDIEVESAIKAIDEANYQAGEIEEVSSLENVALINEDDYDLLIIGSGAAAFSSAIK
                     AIEYGAKVGMIERGTVGGTCVNIGCVPSKTLLRAGEINHLSKDNPFKGLQTSAGEVDL
                     ASLITQKDKLVSELRNQKYMDLIDEYNFDLIKGEAKFVDASTVEVNGAKLSAKRFLIA
                     TGASPSLPQISGLEKMDYLTSTTLLELKKIPKRLTVIGSGYIGMELGQLFHHLGSEIT
                     LMQRSERLLKEYDPEISESVEKALIEQGINLVKGATFERVEQSGEIKKVYITVNGSKE
                     VIESDQLLVATGRKPNTDSLNLSAAGVETGKNNEILINDFGQTSNEKIYAAGDVTLGP
                     QFVYVAAYEGGIITDNAIGGLNKKIDLSVVPAVTFTNPTVATVGLTEEQAKEKGYDVK
                     TSVLPLDAVPRAIVNRETTGVFKLVADAETLKVLGVHIVSENAGDVIYAASLAVKFGL
                     TIEDLTETLAPYLTMAEGLKLAALTFDKDVSKLSCCAG"
     gene            16057..17379
                     /locus_tag="ACF3MF_001370"
     CDS             16057..17379
                     /locus_tag="ACF3MF_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001281642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFE3927375.1"
                     /translation="MSDLLSLPDIKTIEPPQENETDMMFKVEAVGPPERCPECGFDKL
                     YKHSSRNQLIMDLPIRLKRVGLQLNRRRYKCRECGSTFWERLISVDEKRSMTKRLLKS
                     IQEQSMSKTFVEVAESVGVDEKTIRNVFKDYVALKEREYQFETPKWLGIDEIHIIRRP
                     RLVLTNIERRTIYDIKPNRNKETVIQRLSEISDRTYIEYVTMDMWKPYKDAVNTILPH
                     AKVVVDKFHVVRMANQALDNVRKSLKAHMSQKERRTLMRERFILLKRKHDLNERESFL
                     LDTWLGNLPALKEAYELKEEFYWIWDTPDPDEGRLCYSQWRHRCMSSNSKDAYKDLVR
                     AVDNWHVEIFNYFDKRLTNAYTESINSIIRQVERMGRGYSFDALRAKILFNEKLHKKR
                     KPRFNSSAFNKAMLYDTFNWYEVNDHDITDNFGVDFSTLIKNLEKGDL"
     gene            17404..17667
                     /locus_tag="ACF3MF_001371"
                     /pseudo
     CDS             17404..17667
                     /locus_tag="ACF3MF_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003043131.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(17714..17944)
                     /locus_tag="ACF3MF_001372"
     CDS             complement(17714..17944)
                     /locus_tag="ACF3MF_001372"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927376.1"
                     /translation="MNKVHVYNHNKFVKEINSDTNSIAKEIASQSPFAELKMTDEYDN
                     LILTTKGFFLDDVPNQIWLKNELMPALTNLQI"
     gene            complement(18214..18699)
                     /gene="vanZ-A"
                     /locus_tag="ACF3MF_001373"
     CDS             complement(18214..18699)
                     /gene="vanZ-A"
                     /locus_tag="ACF3MF_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HFE3927377.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(18852..19742)
                     /locus_tag="ACF3MF_001374"
     CDS             complement(18852..19742)
                     /locus_tag="ACF3MF_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HFE3927378.1"
                     /translation="MLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHLENSGTSE
                     NTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLLDSNIYMS
                     KEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGYSEHNSGL
                     SLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIRYVGLPHS
                     AIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNLRYEISGN
                     NIDGVIVTVFPGSTHTNSRR"
     gene            complement(20192..20800)
                     /locus_tag="ACF3MF_001375"
     CDS             complement(20192..20800)
                     /locus_tag="ACF3MF_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HFE3927379.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            complement(20806..21837)
                     /gene="vanA"
                     /locus_tag="ACF3MF_001376"
     CDS             complement(20806..21837)
                     /gene="vanA"
                     /locus_tag="ACF3MF_001376"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HFE3927380.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            complement(21830..22798)
                     /locus_tag="ACF3MF_001377"
     CDS             complement(21830..22798)
                     /locus_tag="ACF3MF_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HFE3927381.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            complement(23013..24167)
                     /locus_tag="ACF3MF_001378"
     CDS             complement(23013..24167)
                     /locus_tag="ACF3MF_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-A"
                     /protein_id="HFE3927382.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            complement(24145..24840)
                     /gene="vanR-A"
                     /locus_tag="ACF3MF_001379"
     CDS             complement(24145..24840)
                     /gene="vanR-A"
                     /locus_tag="ACF3MF_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /protein_id="HFE3927383.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            complement(25112..26425)
                     /locus_tag="ACF3MF_001380"
     CDS             complement(25112..26425)
                     /locus_tag="ACF3MF_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003141076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380 family transposase"
                     /protein_id="HFE3927384.1"
                     /translation="MATLHENRLLFNSNVTVSHSGGNLSSDSGLILAKEFMNKFEFSQ
                     ILCKNIQIQDDRLYHVHENESILEQIILQLIAGYPTDSSANILATDPIFQAVLSKKRL
                     ASQSSISRFWDRISTENIVQLQKVNQILIDKARTIRNTNEMIFDLDSTHSDTFGNQEM
                     TDYNAHYQTTGYHPLVAFDGLTGDFLKAELRSGNVYTSKGVAAFTRPLFEHYHSVTPV
                     STIMVRADSGFAMPDLYELCEEYDSLYTIRLKSNRNLYRIADQFITIKDHHDWSKKEV
                     HYYNATYQAKSWGKSRRICIKSTREASELLFRHEFIITNFSKDVSPEMVFQTYSKRGT
                     MENYIKEAKNGFYLDKTDSPRFIENHARMIVSLLAYNIVNFMRTLCFTNETKGYQVST
                     IRLFLFKIAGKIVHSGRRQYLKLSSYHVYQKLFYRILQNIQVLQC"
     gene            complement(26734..27309)
                     /locus_tag="ACF3MF_001381"
     CDS             complement(26734..27309)
                     /locus_tag="ACF3MF_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFE3927385.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            27455..30421
                     /locus_tag="ACF3MF_001382"
     CDS             27455..30421
                     /locus_tag="ACF3MF_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HFE3927386.1"
                     /translation="MKIARGRELLTPEQRQAFMQIPEDEWILGTYFTFSKRDLEIVNK
                     RRREENRLGFAVQLAVLRYPGWPYTHIKSIPDSVIQYISKQIGVSPSSLDHYPQRENT
                     LWDHLKEIRSEYDFVTFTLSEYRMTFKYLHQLALENGDAIHLLHECIDFLRKNKIILP
                     AITTLERMVWEARAMAEKKLFNTVSKSLTNEQKEKLEGIITSQHPSESNKTILGWLKE
                     PPGHPSPETFLKIIERLEYIRGMDLETVQISHLHRNRLLQLSRLGSRYEPYAFRDFQE
                     NKRYSILTIYLLQLTQELTDKAFEIHDRQILSLLSKGRKAQEEIQKQNGKKLNEKVIH
                     FTNIGQALIKAREEKLDVFKVLESVIEWNTFVSSVEEAQELARPADYDYLDLLQKRFY
                     SLRKYTPTLLRVLEFHSTKANEPLLQAVEIIRGMNESGKRKVPDDSPVDFISKRWKRH
                     LYEDDGTTINRHYYEMAVLTELREHVRAGDVSIVGSRQYRDFEEYLFSEDTWNQSKGN
                     TRLSVSLSFEDYITERTSSFNERLKWLAANSNKLDGVSLEKGKLSLARLEKDVPEEAK
                     KFSASLYQMLPRIKLTDLLMDVAHITGFHEQFTHASNNRKPDKEETIIIMAALLGMGM
                     NIGLSKMAEATPGLTYKQLANVSQWRMYEDAMNKAQAILVNFHHKLQLPFYWGDGTTS
                     SSDGMRMQLGVSSLHADANPHYGTGKGATIYRFTSDQFSSYYTKIIHTNSRDAIHVLD
                     GLLHHETDLNIEEHYTDTAGYTDQIFGLTHLLGFKFAPRIRDLSDSKLFTIDKASEYP
                     KLEAILRGQINTKVIKENYEDVLRLAHSIREGTVSASLIMGKLGSYSRQNSLATALRE
                     MGRIEKTIFILNYISDESLRRKIQRGLNKGEAMNGLARAIFFGKQGELRERTIQHQLQ
                     RASALNIIINAISIWNTLHLTTAVEYKKRTGSFNEDLLHHMSPLGWEHINLLGEYHFN
                     SEKVVSLNSLRPLKLS"
     gene            complement(30505..30690)
                     /locus_tag="ACF3MF_001383"
     CDS             complement(30505..30690)
                     /locus_tag="ACF3MF_001383"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927387.1"
                     /translation="MSTLQEKQLQFNPHLLRNEEIFRGASIYKIITIDMMKQIKARDK
                     QIELAENIVDYLLHTNF"
     gene            complement(30843..31286)
                     /locus_tag="ACF3MF_001384"
     CDS             complement(30843..31286)
                     /locus_tag="ACF3MF_001384"
                     /inference="COORDINATES: protein motif:HMM:NF018410.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small multi-drug export protein"
                     /protein_id="HFE3927388.1"
                     /translation="MEIIKYIGAAFSTWFIGFFPYFEIYIAIPAGFAAGLNWFDAFLW
                     ASLGNWMVIPFVDICYEWLMKFNFMKKIMEKSLNGKWENRIEKHGAWVILLLTPLAGV
                     WTIGVIAKALKFNRAKLWIYSATSVGITGLIITILIINGITLNNS"
     gene            complement(31318..31896)
                     /locus_tag="ACF3MF_001385"
     CDS             complement(31318..31896)
                     /locus_tag="ACF3MF_001385"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFE3927389.1"
                     /translation="MKTKDLIIEEFIKSFGENGFEGTSVDYLAKQVGIKKGSIYTHYS
                     GKNEIFTIACEKILDKCIVAIKQLLEVERDKPLDEQLFILLKTVCLESDFLTADEIAF
                     SKRVAILSSSELLSLVDKLLAKYDNFIDDTVSRIFIDCAKQKMLAEEEITSAISVYRM
                     LLENLYIDSLANQNCNEKLNHLWRYFWKGVCS"
     gene            complement(32067..32339)
                     /locus_tag="ACF3MF_001386"
     CDS             complement(32067..32339)
                     /locus_tag="ACF3MF_001386"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927390.1"
                     /translation="MLNALELNRGFLFLWSFSLKIILARKNGTLLEALRAELPAFEQT
                     IVPEFKGAVRAVLKKIHRPSIGVKMGEIANYSSTSSPMGQLKKMFG"
     gene            32263..32454
                     /locus_tag="ACF3MF_001387"
                     /pseudo
     CDS             32263..32454
                     /locus_tag="ACF3MF_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001281642.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(32544..33041)
                     /locus_tag="ACF3MF_001388"
     CDS             complement(32544..33041)
                     /locus_tag="ACF3MF_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaJ domain-containing protein"
                     /protein_id="HFE3927391.1"
                     /translation="MKYIKNVETLEELKKAYKKLALKLHPDCGGSNEEMAQLNNEYDE
                     LFVKLKNTHKNKDGETYTKETTETPEQFKDIINQLFNLKMDGVSIEIVGTFIWLTGNT
                     KPYKDDIKALEFRYSPKKYAWYKAPSDYKKRSRKNYDMDTIRGMYGSQKVKEDKEEKK
                     YLQAN"
     gene            complement(33080..33397)
                     /locus_tag="ACF3MF_001389"
     CDS             complement(33080..33397)
                     /locus_tag="ACF3MF_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927392.1"
                     /translation="MEKTKKLQLEDFTENEFFGTQEQQYLKAQVREELKEQGFIIDSS
                     FEGDFKTWIGVYARPKDKPTYLDPQNDKEAEEQEQYSINGFKQDFSEWFEWEIKNLKI
                     KEM"
     gene            complement(33834..>34537)
                     /locus_tag="ACF3MF_001390"
     CDS             complement(33834..>34537)
                     /locus_tag="ACF3MF_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HFE3927393.1"
                     /translation="EETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRM
                     TEAIISRLSDQGYNLVIEGTGRTTDVPIQTATMLQAKGYETKMYVMAVPKINSYLGTI
                     ERYETMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSS
                     LETPSISAKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKLESLQ
                     PPIPPIPKTPKLPGL"
BASE COUNT        10423 a         6390 c         5778 g        11946 t
ORIGIN      
        1 tattttctaa acatagccat cattgctaag tttccaagtc cgccaccttt tgacactttg
       61 gttgaatacc acatattttg tagggctgac ggtgttttga taatcaacaa gccacaacca
      121 accattaaca taaagtttgg taacgtgtat ttttcagcaa tcatgagtgt aatcatgagt
      181 aagtacaaaa taagcttaat aagcattgtg agtgcttcgg ataacagttc tttgatccat
      241 atttgaaagt aattttgttc gtctgttaaa agcgataagg caactaatgg tgttaacata
      301 gtcagtacca agaaatcggc ataaaagaca cagatcgcta caaaatactt ggcaatggaa
      361 aaggcaaaga atatcacgaa aacaaagaga acaacggcgc taacgccacc attaaagaaa
      421 tttgatacta agaaattacg caatcgttcg ccgatcgttt ccacattcaa atcattagcg
      481 acttgttgaa tcacatattc cccgattggt gcaacaatct ttttgataaa aaagttcatt
      541 gcccagggca acgttgctaa ggcaatagac gagtaaaaca gcttttgaac aatattagcg
      601 gtcaatgcgt caccactccc attagaagct tgtatttgcg cttcaatgac cttatacaac
      661 acaatacaaa ttgcaaaggt cgtagtggca aagacaaaca cgttggtaat ggtgctaatt
      721 aattttatat ttggaatatc aaaagttgtc ttattcgcaa ttttcatgct tgcttctaaa
      781 aggtcgcttc cccaactgcc taataaacta tcgatcgggt gcaaaacact atctacactc
      841 tcttttacgc cttcaaatat tcctgatatg gcatcaccgg cagaacttaa aatgtctgat
      901 ccggtttctt ttatttggtc aattacgtcc atattacatt acaccaccaa tcgttccgct
      961 aacttgccac tttccaattt tttcgttgta ttgcataact acaaatactc caccaatatt
     1021 ttctatattt ttttcttgtt tgctggttac tatccctata acttcatatc ttaaatcatt
     1081 agcccaatca atttgtgtaa acattgatcc tactttctca tcatgttgtc ctttgtttct
     1141 ccaatctgcc cactcataag aaaaatcatt gcgtaggata attttggtat tttgcgctgt
     1201 tttttcagtg tctaagaacc aagtccgtaa ccattggctt tgatcgtcat tttgcttgga
     1261 aatcgttagc ccttttgtac cgtcaacgat tactggattg aaattaaagc ttgcttgtaa
     1321 acctgaatag aaatcatctg aaactttatc gccaaacttg gcttttaagt tatcaatgag
     1381 ttttgtttgt aactcaatcg ggcttgttcc gcctgatcct tctttcaata actctttgtt
     1441 gatctctaaa atcacgtcac cttttgaaaa tgacttgtac caactctcaa aagcttctgt
     1501 cgcttcgtct gctcgttctt tggcacttaa tttgagtaaa tggtcgcttg acccttgaac
     1561 ggcttgtgag ctgttttctg tagcttctcc gcttgcttcc gattggttac tttctttgct
     1621 tgtggtggtg gcggttggtg ctactggtgg ttgattctta ttgttaaaat aagaaatacc
     1681 aacaaaggca agaatgccaa taaacaagac accaatcact atgtttctaa gcacttgacg
     1741 gctaaattcc atttttttaa taccctcgct aggtttaatc cctttttctt cgatttctcg
     1801 ctcaacttgt ttttgaaaca ttgggatatt cccaaaaaat tctttcaatc cattcatttg
     1861 atttcctccg atctttaaaa tggtaattcg ctgttgtcat tgttggttgt gttttcctct
     1921 ataccttcat caaaactact tagaatatca ctcattaatt gttctttttc ttctacttct
     1981 tctgttactt ctgattcgat cggttgttca ggtaatttga tttctttttt atttaagtca
     2041 ttttcttgtt tcttctcatg aaaaactggg gcgcttgcga gttgtacttt tctttgcttg
     2101 tgctgtactt ccaattcttc aatgtattct ttggcaaatt ctgtttgact gcttatataa
     2161 tcttgttgtg aaatttcatg ctttttaaga agatttccga acaattcaaa ttgtggcgtt
     2221 tttcttaaca tgtaaggttt accgtcaatt aacacaatac tttttcttcc attttcttct
     2281 tgttgtaaat tgataacttc cccttcggta attaatcgcc ttttttggta accgtagctt
     2341 tctgacttac ttccgcttcg gttagttgtt tttgcggacg ttttactttc acttgttccg
     2401 cctgtatata ccttgattgt tgtatcattt acttgtcttg aaaagtattc agcggttgtt
     2461 tcctctacac cacctagaca aattttaatg gcatgattcc caatgatcgc tttaaatttc
     2521 ttatctccgt atagttcaaa gccttggggc aatgactgta aaatggtact aactgaaata
     2581 cgataccctc gacatgttgc aagaaaattc tcgtatgttg gaaagtagcc caaattgaca
     2641 aattcatcta gtaacataac taaaggtact ggcaattttg cgttgtgctt atcccctaaa
     2701 aaatataact ctgtaaacat ttgttggaaa aagagattca ctaagccgtc ccaagttcga
     2761 tctaatgggg aaattagcac gtataaacaa atttttgacg ttcctaattc ctcaaagaaa
     2821 aaatcgtttg tactggtaaa ttctgctact tctttatcaa caaaatcttg taaagtcgtc
     2881 aatagactaa taacaatgtt tggtcttgct tcactttgtg cttgtcggaa gcctaaatag
     2941 taactgcgtt ttgcttcgtg tccgtctggc aaacgctcaa attgttcatc aagttctgat
     3001 acaccttctt cgttatagcg tggatcaaat tcttctaaaa agtctaaaat accctcaatt
     3061 gttcttgcgc ttggttcata ttcaaaataa acatatttaa tcagtgtatt taataagttt
     3121 aattgtgcat tgaaccaaaa atctttccgt ttgggatcat tctttgctga tactatgacg
     3181 ttcgcaatct tgtttgtatc atttgatttg cgaatgtaaa gtaatggatt gtacctagaa
     3241 cttagtagaa aatctttaaa atttatgaca accgttttga agccctgggc tttttttatt
     3301 tcattggtta actcgtaaat ttcccctttt ggatcggtta caacaattga cgtactgcga
     3361 ttatttacaa cattaggcaa aacataactt tgtgttttaa atgatcctgg accacctact
     3421 acaaaaatat ttcgattgct tattttgcta tcttcgggtt ggatcacaac atttccgctt
     3481 tgaaatttcc ctaagattaa accgtctgat tctgctaaca aactactcat ttttccccct
     3541 cctcattgac ttttctaata tctttttcat tgacttttca gggatcaaat gaacattttt
     3601 tggtgcgttt atttctgatt cttcccccca ataagccgat ccatgaacag ggtttgtttt
     3661 cccgacaacc tcaaacggtt ggcgtttggt agggtgaaga aagacaaata aaataattaa
     3721 aacaatgatt tgtacaatga agaacggaat catgtaatta gattgaatga tctctaaaaa
     3781 agtattgatc gggtgcttta aaatagttgt aacaaaggta ctcaattcaa tatttgtatc
     3841 attcgcaatg ataaaaggta ataatttaaa cacaatcaat gttactggta ataatagtag
     3901 atagagtata actaggataa tcagttttac ttgctcttgc tttttcttcg ccatgcttct
     3961 actcctctcc taattgaatg gtcgttcttt gagtaatttg ttggttttta atttggataa
     4021 tttggtttat ttcaaaatca ttttttgtac cgttaaaaac ctggtgaatc ggtgctgtta
     4081 ctagatattg ctgtgaatta tccttacttg cataagcaag aatttttatt tcattttcgt
     4141 ttactgaaga cttttgaatc gtgttttgtt gtgggctata tgaattgttt acgttgatct
     4201 cgttttgtaa ttcttgataa acgttgtctg tcgctaattc tttaaccgtt gtcatagata
     4261 tttctttttg gcttttttcg tagttataaa cggtcttgta aaattctttg ataatttttt
     4321 ccgattcgct ttggttagtg ttttgttccg cttgtttgtc tgctagttcc gtctgtacgc
     4381 tttttaaatc actttttaag tgacggatct gttcgccttg ctttattcca aaaacaatca
     4441 tgcctatggt aaccacaagt aaagcaagcg ttgagataaa caaactaact tttattttgt
     4501 caaactccat ttttttctct ccttattcaa cataacttgc aatgtttgca atagaagctg
     4561 gcactactcg ataactgatt gttccacttc ctgggtttac tacattacac tctgatacaa
     4621 gaagcgtacc gtctgcattt acgacttcta caaaggcaac gtgtccgtaa actggatcag
     4681 aaccgaaaga acctggaggg aaagaaattg ccgtacctac tttgggctta tttgttactt
     4741 tatagcctaa agctttccct ttatagcccc attcgccacc attgcccata aaatcatcaa
     4801 ctggttttcc tatttgagcc atacgattaa aagcgtacca agtacattgc ccaaatggat
     4861 aactaccgct tgtgttatag ttgtgtccgt catatcttgg ataacgtaat ttatttttgt
     4921 actcactagg tacatcaact tgaacagcgc cagtattatt agaattgttt tgaacgccct
     4981 ctgcgcttgc ctggctttcg ttaacgtatt caagtaattt tggcacatag aacatatttc
     5041 cgtagttata gcggtaattg tagcccattg aagtagataa agcatttaca taaggtacct
     5101 tttcgccacc tgacatatta atagaaaatt gtttagccaa ctcaaaagaa tacgttccgc
     5161 cattcttcac tacaaaatca acaaaaccac cgccataatt gtacgcttga agagctgttt
     5221 ttatatctga tcctcggttt atagcgcttt tcatattttc tacaaaaaac tctactcctc
     5281 gttgtatgct tcgttcgggg tcttgaatgg tgttaggggg caatcctaaa ctttcgcttg
     5341 attgcatagg atcgccacca ttcccgcccg attcaatttg catgagtgct aagatataag
     5401 gtacatattc cataccgtca tattgtctag cgtacttttc aacggtactt ttgtacctca
     5461 aaacagattc acttaaattt ttgttttctg ttgctagtcc gccactaggg gcggtttgat
     5521 cgttattaaa aataagaagg aagattacaa tgataaagac gaaaaagcct aaaattgctt
     5581 tcgctatcgg ttttcgataa cgaataagca gtttagcagc tgttgctccc atgatatgaa
     5641 atcaccaacc ttcctaatct ttttcagcgt ttgttaattc aatcttttca ctaagcaatg
     5701 tgttgttttc ttctaacaag tcattggttt gttttttctt caagtcgtca tttaaagaat
     5761 tatccttata tatattttct agttcttcac tgttattttc aatcaataag tcaatcatgc
     5821 tgatttgacg tttaggatcg attgctaatt tcttttgtgt aattgatact tgacgaatat
     5881 tttttactgt tggaatatcc tttttcttta ccgcttgatc gattaaagct tcaacaattg
     5941 ttgtatcggt acttgtctga accaggtact caatatctgt tgaattgtca tacgctaaaa
     6001 tctttttgaa gtctgctaaa tagtcgcttc ctggcaaatc aagattttct attttttcgg
     6061 tttccccttg tttgtacaga ctttgaataa tttttttatc tgacttttta tcaagttcat
     6121 aagccttagt gtagtcacca agtttcacgt aaatatcaac ttgttttttc ttaggatagt
     6181 tgagtttttg catatcttct tcgatattct cactatcatt atcaataatc ttatttaaaa
     6241 tagtgatctc tgtttctgcg ctttgctgtg tagccgtaac ttgttttttc tcatttactt
     6301 tcataagaaa aaccgtaccg ccatataacg caataacacc tacaactaac gcaattttta
     6361 agcttttatt tctgcgaatt tttcggacgt ttgctttctt atcctgtaat tcagcagaaa
     6421 agaaattctt ttgttcttcg gttagtcgat tttttattaa atctcttaat gattccaaac
     6481 tttcaactgc ttctacatca tttaaaaatg aatttttttc ttttgttaga atctcaatac
     6541 gattcttctc atacttttca agcgaaaatt taccaaaaaa actacaaata aaatttttcc
     6601 actgctctaa ttcttcttta gttgagtaag gcaaattacc aaaatgatct gctttataaa
     6661 taaaaagcaa gtcacgtgta tctttgagta ggatattttg cattgctaga taggtgtttg
     6721 ttttttctag tacattcatt tcaagtaatc gattcactat atccaattta taaaaatcag
     6781 catattcttt taaatcaagt agtggtgtat agccattagg acggtgataa acaatttcta
     6841 gttttccgtc tttggttaaa atttcctcga catcaacaaa atattgttca ctttcttcta
     6901 catcaaaaat atgttctcga ttcgtcaaat atttttcgtt tatttggacg acaatgacat
     6961 tctcttgata gtagaattgt aaatttttca agattttgta tttcattttt ttctcccttc
     7021 tattgaattt tcgatcttaa caaccaattg atctctttct tcggactaac gccgtaaata
     7081 tcttcatatc cgcctgggtt aagcaaacgc atttcttcct gggtcaaatc gactttaatt
     7141 ttagccctct ttgttccatg aaagagtaaa gcttcccctt gacgttttga ggtaatgaaa
     7201 gataattctt tttttgtaag tttaagtttc aactcgtttg agataccttg cgcttccgtt
     7261 tcatcaagtc caaagaacac ttttgtaaag ctattcccaa taattgcttt accgatatta
     7321 tcaggtgctt ttaatacatc atcaatctgt tgggttgata cggtacaatc ggcgttatat
     7381 tttctaaagc gtttgtaagc ctggaagaaa aaatctgcac taattttatt tttcagtaaa
     7441 aagtgaaatt catctgcata aacagacgtt acaatttgcg gattgttggt tatttcttca
     7501 aatagataac taaagctgtt gaggtatgct aaatctctga ttccttcttc ggtctgtaaa
     7561 tctcgcaaag agaagcaaat taacggattg cttaagtcaa tatttgtatg accgttaaat
     7621 atggtacggc ttccgattgt aaaatcttct aatgaataaa taaaatcttc aattcgcttg
     7681 tatcgtttgg gatcagtttc ttctaatgct ttcaatcgac tttctaagtc tgaaaatgtt
     7741 ggaaaatcgg tgttttccat ttttgacaag tttttctttt cgtataaagt ggtatagcat
     7801 tttttcgctt ctaacttaat aatagataat tgactgtcag tcaaagagtg atccaccatt
     7861 aggaaatatg gcgttaaaat attcattcgt ttactgattt ctttatcaat atcattttca
     7921 gtcatttcaa aatctttgtg ctttatttca agattttcta caagttcgtc ctcttcaaaa
     7981 tcggataacg attcttttaa atccacatct ggtgtattgc gtgagtagat ttgaaacgga
     8041 ttgatacgaa catctgacat agacgaaaga ttgattattt cgccccctag agaacgtaca
     8101 cgttctgttt gttcatcttc gggatcaaat aaaacaattc tgtgttttag ttctgttgag
     8161 ttatcagcaa aagcatattt tttcaaatag tctgacgtta ggtaagtggt ttttccccca
     8221 ccagataaac caaaaacgaa tttattacga ttgactacta attttctgtt ggtgtaatca
     8281 atactaacga tattttcagt atctttatta attccctcaa taatcatatt tttagtaaat
     8341 acacttaatt cattatcatc aaaaggaaaa atactgcttg cactgattga attagcgatt
     8401 gtgtacgtgt attcaggcac ttcattagat tgtaaaggta aggcactcca atacgcttta
     8461 tcaatcatag tatatggaat caaggctttt actccacttg cgatacaacg tgtttcaaaa
     8521 tcttcacaca attttttcag tttatcttcg gacttacttt tgatcaaaac ataggtatat
     8581 aaataaagat aagaagtgtt ttcgtcaacg gcttgttcta actgcgtttg tgcaattttc
     8641 atttcacgtt ctaaacggat aatcgtcaac ggatcatgcg aacgatcgat ctctgcttgc
     8701 ttgttcttaa tggttctgtt gtaataatca ttcaatgagt taccgtttgc tttagtgtaa
     8761 taatgagata tggttatatc tccactcatt ttacgaatac gattaaacca atttcctctt
     8821 ggtttattat tgtattttgt aatgacatag ggaactgcgt atgaatcatc aatcaataat
     8881 ttgtcacgtt ctactgtaaa gttaaatggt gctaaatcag atacaacgtc cgtatcaact
     8941 tcgggtatta caataatttt ctcttttggt atcttctcca ttttaacgct cctaactatt
     9001 caaaaccttt ttcatctcgc caatcgtaca aatttcaacc tgacaatcat atttacttaa
     9061 aaatgcaatt aaagctgttc tgattgttct tgtcttatca cgtaacactt gataagacaa
     9121 ttccaaactg tcgtatgttt cctttgaaat tggttcagaa ttaattacaa aatgttgttt
     9181 ctttgaagtt tccatgttac ttgctaaatt tctgtaatgg taataatagc tagcttttag
     9241 ttgtaataaa gcttcgttat gccctggcat tttgcgataa ttttctactg tattccccca
     9301 ggcttctaca aaatcgtcaa tttctactgg tacattctta gaagtgatct gcggttcata
     9361 tagaacgttt tgagatagaa agacaccaaa atcttcgttt aacccttctt gctctgatac
     9421 tggcaatgta tcaacgttta agccgtcaac ttttagcata ctcacaaggc taaattgctt
     9481 tttttctggc tgataaacga caaaaaagtc tttaaaaacg ccttgaaatc gggaactatc
     9541 ttcccaataa atcatttctt ttatcgtatc gcttttttta ttatcgttac ttttggaact
     9601 tttttttaga aaatcaaaca atgaaatcac ctctctttta cactcgttct tttggctttt
     9661 tgtaatagac ttttggtctt ttagaaaagt cttttctttg cttcataaaa tcagatatag
     9721 aaatgttagg tcggtctgta attggtttaa tcgtataaaa cgcccataca ccaccaaatg
     9781 acaccaaacc aacaatgaca tagataatta aaggaaaaac ggctgtgcta cggaaaataa
     9841 gaattgccaa tagcacgctt attaatgccg taccgatcgc ttttgctgat tgttttaaat
     9901 ctagccctaa aatgactgtg taccgatcag atacattgga cggaaaaaac caagtccgcc
     9961 ctttttcagt gtctgcattt aacaaatcta atagggcttg tttcacttga tcgctattca
    10021 taactaactc ccttctctat taagcaagta agccatacgc ccaaggtact aaccaaacca
    10081 acgccccacc taatgccgta acaagcaagg ctgttcccaa ggctttatac atggtatttt
    10141 tttcttgtgg gtcatcaata gacggcaagt atttaataac aatcttcgca caagcaatcc
    10201 caccaactac aacaattaag gctgttaaaa caccttttat agtgttaccc gcttgaacta
    10261 atttcgcttg tggatcagtg gctgcaaaca ctggatcagt aataaacaat gtacccaacg
    10321 caacaaccgc acttccaagc ttaaactttg tatctttgat aaattttttc attttataca
    10381 cctcttgttt ttattttatc gcaaaggaat attcctttgt aatgattgat tttcttttgc
    10441 ttttgtttgc ttaatcaatt tgtctaggtt tcgttttttc tgtagttggt taccactcaa
    10501 caaacgatta attgacttcg caaattggaa catttttaca gtcacttcat ttttttctgg
    10561 tacgtcttta tccaattctt gggattgatc tttattggta ttttcaattt ctttacttaa
    10621 ttctatctta tcagaatcag gtaaataagc attgcgatta acaacctttt tcagattttg
    10681 ttttgctaat gggcttagtt catcaatatg tttcatgcta tcttgaacaa aaaatacacc
    10741 ttgacaatca ttaggaattt tcaccgtctg aatattagtt aagaagcctt ttgattgttc
    10801 caacatggaa ttaatttcct cactgctgaa tctagcaact ccttcgactt tagaaaaatc
    10861 agttgttttg taatagtcag cttttgcaag taacatttcg ccttctatga ctgaatctat
    10921 tgaaacattt ttatcaaatt ttctttcaac ttctgattga acatattcta tcaatccttg
    10981 ttttattcct attagttttt ctttcttaat tgataaaatt tcttttcttt cagggttatt
    11041 ttcttttgtt atactatctt caacttgttt aatttttgaa tcaagataac ggctagtttg
    11101 aaatggtttt tctttaaaaa tctttttact ttcttctttt tctactactc tttcattgta
    11161 aatgacctct gctaactgat ctttattcaa taactgtttt ctaaatatgg tttcattaac
    11221 cattgctcta acttcgtgat ttgaaaattt gtcaatattc aaacttggat aagatttttt
    11281 gaagaatctt tctgcttgtt tgtctaaaat ttcatttgcc tttgtaagca tatctcgttc
    11341 actactaatt ttacttaaca tcaaacgttg tttttgaatt tccattttat tattaaagat
    11401 aagtgaattt tcccatcgtt ttaattcacc taatcgttta tcaatgtttt catcattaat
    11461 aaataattta aattcttttg aaagattttt cagttctcct ttttccaaag gtgagaaagt
    11521 tttttcaaat tttaaagtga agttttggtc ttgttttaac actttctctt gactttcaag
    11581 tttatcaagt tcggctagaa tatcattgta actttgaatt tctaaatttt ttctttttaa
    11641 ctcacttata actccttttt cttctaattt ttttgagtaa aaaccttcat gaattgttgg
    11701 tagttctttt tttccaagtt ccgcatgcga tttttctgta atttgttgat cgatatttct
    11761 atcttttaaa tattggttga ctttatcagc ccaatcttta cgaatttcag aaacaagaga
    11821 ttttctatcc caatcatttg ttttaataga aaccatttta attttaccat tttctaataa
    11881 aatcgggttt ccattttcat ctagtttagg tatctttttt cgcttgttaa gaatatttcc
    11941 ttcactatct acttctctca ttgttagcat aatgtgagca tggggattgt tttcatcatc
    12001 tctatggata gctacatctg caatcattcc ttcgctgaca aaattatctt taacaaattc
    12061 ttctatcagt gatcgttgat ctgtattatt taattcaatt ggcaatgcta catttacttc
    12121 tcggcaaagt tgagaattca cctgtttttc tgctaattcc attttgttcc ataaagtctg
    12181 tctatctaaa aattcattag gtacataatc aggctttaaa ataaaagctt ctggtttaac
    12241 agttctatgg ttgtatagat tagttttttc atatagttca ctatacaatt tttcaccgct
    12301 tcgataagaa gccattgcaa ttaaacttct ttttccgcct tctctttttg ctattgtcat
    12361 agataaatgg aagattgcca attgtatcac ctctctttct tttcaaacat gagcgtagcg
    12421 aattttaaca aacacgcttg acgataaaac gaaatgtaaa ttaagtttta tagcacaatt
    12481 accactaaat gaaatttagg ggtataagtg cgcccttagt aaatcatcta agggaatcct
    12541 tgataaatta attttaccac ttatcattat aaaagtaaat atgtttaatc tgacattttc
    12601 atttatattt attgatttta gaaaaataat ataatatgat agagttacat aatatattag
    12661 gaggcgtatt tcatggaaaa tcaagatcaa aatattaatg caattaatgg taattttaat
    12721 tctaaaacta agcccaaaaa aagaaagaag aaaactgttt ctgatattga acttcaaatt
    12781 aaagaattac aaaagaaaaa agaagaatta attctaaaat caaaagcaga tattggtgat
    12841 tttgtccttt ctactctttc aaaacttgat atttctattg aatcgattga agaaaacaaa
    12901 gaattattct atgacgaatt agaaacttta ttaaatgcga atagtcaaaa tttttctgaa
    12961 ttacttaaat agttatggca aataatgatt taaatgacat caacaaaaga atagaaaaac
    13021 taaaaattca aaaaaatatt ttgcgagcga atagcgagca aaatattaac agaaaaagaa
    13081 gaacaaaacg tctaattgaa aaaggtgctt tgttagaaaa gtattttgaa attgactatt
    13141 taactgtaga agaaacggaa gaatttttaa aaattttttc tgaatatatt aaagcgaata
    13201 aacctaaaaa gtatcaaaaa aaggaaaaat aattttcctt tttttgatac ttttttaaat
    13261 aaaattgatt gttcttaatg tttgtccttc cttttttaat tgctttaata tttcatttac
    13321 tgattctata tccaaatcgt accaatcacc aaaagcgata atatcacctg atactttttt
    13381 ttctataaaa tcaactgtta aagttatttc tcttgttgac attggcgaac gtgcttctat
    13441 ttgatataaa tcaaaatcgt atttttgatg attatttatt cctctcattt ctgttactgt
    13501 cgcttttata acttttaaaa tattaccttc aaaatttatt ttgggtcttc ggaatatata
    13561 gtggaattac tttcttaata gtttaaaaac aactggtgtt taaatcggat tttctggtgg
    13621 gatgttagga caatcaatag tattatataa aagtatcaat cacatacgag tgatacgttg
    13681 gggaaaaata aaatagtcca atttacttga ccgcgtacta tggtacacgg tttataatat
    13741 tcatggggtg aaataagatg atttatcgca ttagtgagtt tgcagataaa tgtggagtta
    13801 ataaagaaac gattagatat tacgagagaa aaaatttatt acaagaacct caccgaacgg
    13861 aagctggtta tcggatatat tcatatgatg acgttaagcg tgttgggttt attaaacgaa
    13921 tacaggaact tagtttttct ttaagcgaga tttataaatt acttggtgtt gtagataaag
    13981 atgaagttcg ttgtcaagac atgttcgaat ttgtttctaa aaaacaaaag gaagtgcaaa
    14041 aacaaataga ggatttaaaa cgaattgaaa ctatgttaga cgacttaaaa caacgatgtc
    14101 cagatgaaaa gcaattacat tcgtgtccaa taatagaaac attaacatga gacattaacg
    14161 aaaggggctt ttttatgaat aaatttaagg taaacattca aggaatgact tgtacgggtt
    14221 gtgaaaaaca cgtagaatca gcacttgaaa agataggtgc taaaaatatt gagtctaatt
    14281 ttcgtcgtgg tgaagcagta tttgaactgc ccgatgatat tgaggttgaa agtgcaataa
    14341 aggcgattga tgaagcaaat taccaagccg gagaaattga agaagtatca tcactagaaa
    14401 acgtggcgtt aattaatgaa gatgattatg accttcttat tattggttct ggtgctgctg
    14461 ccttttcttc ggcaattaaa gctatagaat acggtgcaaa agttggaatg attgagcgtg
    14521 gaacggttgg gggaacctgt gtgaatattg gctgtgttcc gtcaaaaact cttcttaggg
    14581 caggggaaat caatcattta tcaaaagaca atccgtttaa aggtttacaa acatccgctg
    14641 gagaagtgga tttagctagt ttaatcacgc aaaaggataa attggtgagc gaacttcgga
    14701 atcaaaaata tatggattta attgatgaat ataattttga tttaattaaa ggtgaagcaa
    14761 aattcgttga tgctagtacg gttgaggtca atggggcaaa gttatctgca aaacgctttt
    14821 taattgcaac aggtgcatcg ccttcgttgc cccaaatttc aggacttgaa aaaatggact
    14881 atttaactag tacaacactt cttgagttaa agaaaatacc aaaacgatta actgtaattg
    14941 gctcaggata cattggaatg gagcttggac aactatttca tcatttaggt tcagaaataa
    15001 cgcttatgca aagaagtgag cgacttttaa aggagtatga tcctgagatt tcagagtcag
    15061 ttgaaaaagc gttaattgaa cagggtataa accttgtcaa aggggcaact tttgagcgtg
    15121 ttgaacaaag tggagagata aaaaaggttt acataacagt aaatggcagt aaagaagtca
    15181 ttgaatcaga tcagttactt gttgccactg gaagaaaacc aaatacggat tctttaaatt
    15241 taagtgcagc aggtgttgaa actggaaaaa ataatgaaat cctgatcaat gattttggtc
    15301 aaacaagtaa tgaaaagatt tatgcagcag gagatgtgac gttaggaccg caatttgtat
    15361 atgtagcagc ctatgaaggt ggaattatta ctgataatgc tatcggtgga ttaaacaaaa
    15421 aaatagattt atcggtagtt cctgctgtta cgtttacgaa tccgacggtt gcaacggttg
    15481 gtttaacaga agaacaagca aaagagaaag ggtatgatgt gaagacatct gtattacctt
    15541 tagatgctgt tccaagagca attgtaaacc gtgaaacaac cggtgtattt aaactagtag
    15601 cagatgcaga aacactaaaa gtattagggg ttcatattgt atctgagaat gcaggagatg
    15661 tcatctatgc agcatcatta gctgttaaat ttggcttaac gatagaagat ttaacagaaa
    15721 ccctagcacc atatttaaca atggctgaag ggctaaaatt agctgcactt acgttcgata
    15781 aagatgtttc gaaattatct tgttgtgcag gctaagggaa ctttttttac aactccctat
    15841 tcaagtgaac cagctaatac tgtactaaag gtgtgcagta gtttagcaaa gtctacaaaa
    15901 gatttcatac actattttgc gatcacccat tatataaatg ctttaaggga ttttctaagt
    15961 gcatttgtgg tcacaaaaat aatttaacaa tgatgatttc gacatcaaat ctataattga
    16021 taccttaaca ccgcagagta ataaaggatg aacaatatgt cagacttatt atccctacca
    16081 gacattaaaa caatagaacc accacaagaa aatgaaaccg atatgatgtt taaagttgaa
    16141 gcagtcggac cacctgaacg ttgtcctgaa tgtggttttg acaagttgta caaacacagt
    16201 tcaagaaatc aactaattat ggatttgccc attcgtttaa agcgagtggg cttacaattg
    16261 aaccgtagac gatacaagtg tcgtgaatgc ggatctacct tctgggaacg cctaatatct
    16321 gtagatgaaa agcgtagtat gaccaaaagg cttttaaagt ccattcaaga gcaatccatg
    16381 tctaagacct ttgtagaagt cgcagaaagc gttggtgttg acgagaaaac tattaggaac
    16441 gtttttaagg actatgtggc actcaaagaa cgtgaatacc agtttgaaac tcctaagtgg
    16501 cttgggatag acgagataca tattatccgt agacctcggc ttgtattgac taatattgaa
    16561 cgcaggacta tttatgacat caagccaaac cgtaacaagg aaacagtcat ccaacgtctt
    16621 tcagaaatca gtgacaggac ttatattgag tacgtcacaa tggatatgtg gaagccttac
    16681 aaagacgcag tgaacactat ccttccacac gctaaagttg tcgtagataa gtttcatgta
    16741 gttagaatgg ctaatcaagc cttagataac gtcagaaagt ctttgaaagc ccatatgagc
    16801 caaaaagaaa gacgtaccct tatgcgtgaa aggtttatcc ttctaaagcg taaacacgat
    16861 ctaaatgaac gtgaatcatt cctcttagat acttggttag gtaatcttcc tgctttaaaa
    16921 gaagcctatg aactcaaaga agagttttac tggatatggg atactcctga tccagatgaa
    16981 ggtcgtcttt gttatagtca atggagacac cgttgtatgt ccagtaactc taaagacgca
    17041 tataaagacc tcgtgagagc cgtagacaac tggcatgtcg aaatattcaa ctactttgat
    17101 aaaaggctca ctaacgctta tacggagtca attaacagta ttattaggca ggtagagcga
    17161 atgggtagag gttactcgtt tgatgcctta cgagccaaaa tccttttcaa tgagaagctc
    17221 cataaaaagc gtaagccacg atttaattca agtgctttca ataaagctat gttatacgat
    17281 actttcaatt ggtatgaagt gaatgatcac gacattacag acaactttgg tgtcgatttt
    17341 tccacactta ttaagaattt ggagaagggt gatttataag cccttttcca ccatgaaatc
    17401 cgaatacccg aaatatataa atatcaagca gaatctgaac gaaagaatat aaaagaaaga
    17461 caagcccagg gaataaagat tgctaaagac ggtaaaaaat atagaggtag aaaaccttta
    17521 tttacaaagg atagccctag attacagcat gcttttgaat tatataagaa tggatattca
    17581 gacaaagagg ttcaaaattt aactggtatt aatcatgaaa catttagaag atataggatt
    17641 aaacataata ttcaacgcaa tatataaaat aacctcacct aattatacta atgtgatcag
    17701 gtgaggttat tttttaaatc tgtaaatttg taagagctgg cattaactca ttttttagcc
    17761 atatctgatt aggtacatca tctaggaaaa agccttttgt tgttaaaatt aagttatcgt
    17821 attcatctgt catttttaat tcagcaaatg gggattgact agcaatttct ttagcaatgc
    17881 tattcgtgtc gctattaatt tcttttacaa atttattatg attatataca tgtaccttat
    17941 tcattttatt tattctcctt tatggggtac cgtcaggaaa atgcggattt acaacgttaa
    18001 ggaaatttat taaagagacc aattcctcag cactaaaatt gataattggg ctttctttgt
    18061 tactatagtg ttaggtaagc tttttacttt atcaccggtt ttcccctcac ttcacaccta
    18121 cgggcgagtt tccccacatc ccgttttcca tctaatccaa ttcattcaat atctttatgt
    18181 gtatgaaaga tcagattgct tgatttagac atcttacacg taatttattc ttaaatgggt
    18241 acggtaaacg agcaataata cgagcaaaag tatacctaca aaaataataa ctctgtctaa
    18301 ttttttttga ttcatatgct tattgcttaa accatataat ttcagtccaa gaaagcctcc
    18361 aacagtattt gtaattacat ctgttatgtc tgtcgctcca atagcgaaga taaattgaat
    18421 tatttcaaaa gtaagactta aaaccagtac aaaagcaaac ttaggtaaaa atccgatttc
    18481 tttaaaattg acattcaaaa gcaagccaaa tggaataaag attataacat tatctatcat
    18541 ctctctgaaa ttcccagtag cagtaaatgg agtcaagtta agacttcttt gatgataatt
    18601 aaatactgat aaaatattgt attgtaattt gaataacact aaccagatta gtgtcactaa
    18661 atataaagct agcaatcctc tagataatat ttttcccaat ataatttcct ctaattcttt
    18721 tgtttaagtt gtatcattag tatagcaatg tcctagttaa cgtgggtttt aaattaaaaa
    18781 gctaacgtta ccccaaaagt gctagtacaa taatgctgtt cattaatttc gttggtttca
    18841 ttccgccatc cttacctcct tgaattagta tgtgttgatc cgggaaacac tgtcacaatt
    18901 acaccgtcta tattgtttcc tgatatctca taacgaagat tagtcggcac atgaatggtg
    18961 gtatttttag taacaggata ataaaagatc tcatattttt ccccatttac actaacagaa
    19021 atggtttttt cttcttttag gtaatccata tattcctcga gaacgaaatt cttttctttc
    19081 ataatcgcac tatgtggtaa accaacatag cgaatatgcc atggttcata ttgaattcct
    19141 gttaactctg ttttgtcctc tggataacgt aaaatgaacc cgtatttcca agcattttct
    19201 tctatccact ttccttcagg ggctcgttcc attttcgtca agcttgatcc tacatctagt
    19261 gataaacctg aattatgctc actataacct gctggtaagg catactcagc ccccatttct
    19321 tggtaaagca cactttgctc atcaaagtct cgatagccac tattaataat aaaatgacta
    19381 acgccaccct ttacagcatc attgaccatc tctgaaaatt tttgtgctat ttcttttgac
    19441 atataaatat tactatcaag caacccgtat ccatttatta attcgtcatg tttagataaa
    19501 ttcacgatat ctgacttcac actttcttgg cgaacaggat atttactatt gattaatagc
    19561 agatttcctt gataaacctg ttcttctgta attgttttct cttgggtatt ttcagaagtc
    19621 ccactatttt ctaaatgttc tttgggattt tgatcataat tttgaaattc gactttttcc
    19681 tgagaaaaca gtgcttcatt aacgtagtca taacctaagt atattaagaa taacaataac
    19741 aataaaaaaa aacaacttct tcattttcag tctcctcctt aactatatag ttggaagtat
    19801 gaaatatttc tagaatcttc cccttaaacg gcacaatctc gtttgagatt gtgccgtttt
    19861 gccccgtaaa ttacagtcaa ttatttcgcc ctactggatt tactattatc accaatgtag
    19921 atgaattttc ataagtgata cccatgctga atttaacgag gctgaactgc ctgttgacaa
    19981 tgggcggtgt gaaataccac ccctctatgc gatcagtctt attatcaggc tatcttgccg
    20041 cagcgcacgc agataatgac cgcaatatcg ctctgcctta catcttcaat actatctact
    20101 atatataaat tccctaagaa ccagttacat acgtcgggtt tcctgccgaa agagttagct
    20161 tatatagttt gtccgtgcaa cggttaaaag tttatttaac ggggaaatca aaatagctat
    20221 tggggtatgg ttcgtctctt aatacatagt gccaccattc gaggctatat gcttcaaacc
    20281 cactgttttc catgatggag cgcaaacgtc tgcgattttg cgcttcattg catgatattc
    20341 catttgccgc atgatgagag cgttcatcca taaaatcaaa tcggctcccc attggtacaa
    20401 gctcacccgt gtctaatcga taaagcgtaa gatcaatggc actgccgcgg ctatggcttg
    20461 attttgaagc cacgtatcct tttgaaatca tctcagttcg gtcaatattg ggataataac
    20521 tttcctttgt caggttattt tccggctgtg cagcccattg cataaaacag tttacagcac
    20581 gcttaggacg gtaaccgtcc catagaagca atccgtaccc ttgggtagca gccagttctt
    20641 ttgccttcaa aagcgattca gccaactcgt atgtccctac aatgcgattt acttcataac
    20701 cgtcaaccgg ttttccggtg aaattatccc aagtggcata tttagcgtcc caacgaacac
    20761 cgtgtactat ttcatctaaa aaagtaaatc ctatttccat gcttatcacc cctttaacgc
    20821 taatacgatc aagcggtcaa tcagttcggg aagtgcaata cctgcagcgg ccatcatacg
    20881 gggataacga ctgtatgacg tgaaaccggg cagagtattg acttcgttca gtacaatgcg
    20941 gccgttatct tgtaaaaaca tatccacacg ggctagacct ctacagccga gcgctttata
    21001 tatttttttt gccgtttcct gtatccgtcc tcgctcctct gctgaaaggt ctgcgggaac
    21061 ggttataact gcgttttcag agcctttttc cggctcgact tcctgatgaa tacgaaagat
    21121 tccgtactgc agcctgattt ggtccacctc gccaacaact aacgcggcac tgtttcccaa
    21181 taccgcacaa ccgacctcac agcccgaaac agcctgctca attaagattt tgctgtcata
    21241 ttgtcttgcc gattcaattg cgtagtccaa ttcgtccgcg ctattgactt ttttcacacc
    21301 gaaggatgag cctgaacgcg ccggcttaac aaaaacagga taggtaaacg tagctgccac
    21361 cggcctatca tctttattaa taacccaaaa ggcgggagta gctatcccag catttttcgc
    21421 aacgatgtat gtcaacgatt tgtccataca aattgctgag ctttgaatat cgcagcctac
    21481 aaaagggata ccggacaatt caaacagacc ttgtatggat ccatcttcac ctgacttgcc
    21541 atgcaaagct gaaaatgcta catcaacatg gttgatttca tattcatggt tctttttaac
    21601 aagtaatccg tgcatttttt tatccggcga gagtacagct gaatagcaat tgtcgttttc
    21661 ccattccgcg caaggttttt cgcacatttt ccatacacca gatttcgtaa ttccaatgta
    21721 taacggctcg tatttttctt tattaatgtt agcggctatc tctattgcag attttaccga
    21781 tacgtcatgc tcctctgagc aacccccaaa cagtattgca acttttattc tattcatgct
    21841 cctgtctcct ttcaaaatcc aaacagtttt taatggtttt ttcaacggta tcacgcaacg
    21901 cttgctcggt ataataggcc gtatgcggtg tgattatcac gttaggcatt ctttgaagtt
    21961 taagtaaaaa ttgattatca attggttttt gggtgcaatc agagtagaaa aactcttcct
    22021 ctccttccaa tacatccaat gcggcaccgc ccagtttccc gttttctaat gctttaacca
    22081 actcataggt atctacaagt ggaccgcgcc cagtattgat aagaaatgct ccttgcttca
    22141 ttctctgtat ttgttcgtgg ctgataatat agtgcgtatc cgtattgagc ggcacatgaa
    22201 gcgtaacgat atcgctattt tgcagcaact catcaaacgg tacatagttt acctctatac
    22261 ttcggctgcg actataagcc aacactttac atccaaatcc tcgcagccgc tcaataaccg
    22321 ctttgcctat ctggcccgtt cccaccacac caactgtcat gtcgctgagt accttgccac
    22381 ggtcgctgtc caacctgaaa tcatgttttt ccacagagcg cacaatcgat tttacgttgc
    22441 gtactgccat aagaattagc atcatagtat aatcggcaac gctatccggc gagtacgcca
    22501 cattgtcgac agtgatgccc attctcttag cagcagttgt atctatatga ttgcagccga
    22561 tgcttcgggt agaaatatat ttcacaccgg ctctcttcag cgcaagaaga atagaggcgg
    22621 aaatctctga tttatgtccc acactgatac attgattgaa aggcgcggat ttggcgttgg
    22681 attccgacac gttggcgtta attatcgttg ccataacgcc aaagcgaggc gaaagagcat
    22741 ggaatgcatc tgcctcatcc tgctcacatc cataaacagt aatgccgatg ttattcataa
    22801 ttaagaccaa ccctttctgt gaaaggcacc aaataaaacg gggatgccaa tggtaatctt
    22861 gtcaaatctt tctctgaaga acgaaaacgg ctcgttctta cggtattaag tctaccgtgt
    22921 aagaacgagc cgtttcttaa tattaaattg ttaatttcct aagaaaaagt aaagataacc
    22981 ttgagatttt cctaaaaaat tatatacatc tcttaggacc tccttttatc aaccaagtct
    23041 ggcatcgctg gaagctctac cctaaacgtc gtatagttat cattgctttc cgcgtaaatc
    23101 tgccctccat gctgaacaat aatttctttt gcaatcgcca atccaagtcc cgcgccaccc
    23161 gtatcggaag aacgagcatt gtccagccta tagaactttt caaatatggc agctagctta
    23221 tcttttggga tgcttccagt gttcttgaat tcgattgaca ccacatcccc ggagaggccc
    23281 gcggtaatgt caatgatgct gttatcctca ctgtatgcag cggcgttttt caaaatgttg
    23341 ttaaagactc tcgcgagttt atcagggtcg ccggacacgg tcagatcctc gggggcgtga
    23401 ataaccgcct gttttccatg tgcggaaagc tgaggataaa attcatcggt catctgcacc
    23461 agcatatagt ataggtctat gtgcgttttt gttagcgtta tcgtttgtag gttataccgt
    23521 gtaatctcaa aaaactcgtc gattagctgt tcgagtcgat acgctttgtc caacgtgata
    23581 tgcacatact ttgccttttg atctaccggc atgtctggag cctcgtcaag caggctcaaa
    23641 taaccgataa tggatgtaag gggcgtttta atatcgtgcg ccaagtacat aacaacgtca
    23701 ttttttcttt gttcggccag ctttgcatcc tgctctcgct tttccagagt ccgttttaat
    23761 gtgttgagct tttgttccat aacatccatt tccgcagaaa gctcaatttg tttatcttcg
    23821 ttctgaataa gtacatcaat gccggtattt atctcgtcaa agtattttgc gaattttgaa
    23881 agcatgacgc gacatagaat aagaatacta atgacaatcg ccacataaat aaagatatct
    23941 atattgttcc gtatggaata ttgatataat ttcatcgcgt ccaggtgatt taagtcatat
    24001 ttgttttcca aaatacttaa gatccaatcc ccaagtttcc ctcggatcat tgaacgaata
    24061 tacaacacga atacaattgc taccacaaca attgcaacga tatacatgta aagttttcgt
    24121 tctagtttgg aatagtcgtt ttttttattt ttcaatttta taaccaaccc cccataccgt
    24181 ttttatatat ttcggattat caatggtgtc gttcattttt tcgcgcaaat gccggatatg
    24241 cacggtgatg gtgttgttgc tcttgctgaa atattcgtcg ccccatatct catgaaatag
    24301 cagctcggag ctaaccacat tccccttgtt ttcacagagg attcgcagta ttgaaaactc
    24361 ggtgggagta agggataact gcttctcgtt cagataacac tcatgggtgt taacattaat
    24421 gacaaggccg gagtggacga taacattttc gttctgctcc tttactccac tgaatttttt
    24481 gtatcggcgc aactgggcct ttacccgagc aattaactcc agtgggcgaa agggcttcgt
    24541 tatataatca tccgcgccga ttgttaaccc tgtaatttta tctacctctg tatctttccc
    24601 ggtcagcatg ataatcggat aggtgtgctt gtcccttatt ttttgacaga tagtaaggcc
    24661 gcttgtgccg ggaagcatga tgtccaatat ggcaaggtca atctcagact tgtctataca
    24721 ttccaatgct tctttggcgg tatagtattt gaaaaccgta taattctcgt tttttaagta
    24781 taattcaacc aaatcggcaa tttcatgttc atcatccaca ataagtattt tatcgctcat
    24841 agttatcacc ctttcacata agtttgccct taataattta tcagattata gggccgaatt
    24901 tatacctgaa taattcatac tttttataaa ctaccaaatt ttataattat ctgtttagtt
    24961 ttatgctcaa tggttctttt tctcaaaaat atttttctaa agggtttaat ttatttttgc
    25021 taactgatta agttcaagaa agacctcatt ttgggcgcac tcatcctatc ggatggttaa
    25081 cgaatttttt tgaatggcgc aataaacgca attaacactg cagtacctga atgttttgta
    25141 gaatccgata aaatagcttc tggtaaacat ggtaactact taatttcaag tattgtcttc
    25201 ttccggaatg aactatcttt ccagcaattt taaagagaaa taagcgaata gtagaaacct
    25261 gatacccttt cgtttcattg gtaaaacaca gtgtccgcat gaagttcacg atattgtaag
    25321 ccaataggct tacgatcata cgagcatgat tttctataaa acgtgggcta tctgttttat
    25381 ccaagtaaaa gccgtttttt gcttccttaa tgtaattttc catcgttcct ctttttgaat
    25441 acgtttggaa aaccatttct ggagagacgt cttttgaaaa attagtaatg atgaattcat
    25501 gtctaaaaag caattcacta gcttctctgg ttgattttat gcagatcctt ctggattttc
    25561 cccatgactt tgcttgataa gtggcgttat agtaatgaac ttctttctta ctccaatcgt
    25621 gatgatcctt aatggtaatg aattgatcag cgattctgta cagattacga ttggatttca
    25681 aacggatagt atacaaacta tcgtactctt cacaaagctc atacaaatca ggcattgcga
    25741 atccactatc tgcacgtacc ataatagtgc ttactggtgt cacagagtga taatgctcaa
    25801 ataatggacg agtaaatgct gcgacgcctt ttgaggtgta gacatttcca gaacgaagtt
    25861 ctgctttaag aaagtctccg gtaagaccat caaaggcaac gagtggatga taaccggttg
    25921 tctggtaatg cgcattataa tcggtcattt cttggtttcc aaaggtatca ctgtgagtag
    25981 aatctaaatc gaaaatcatt tcgttcgtat ttcgaatcgt ccgtgcttta tcaatcaaaa
    26041 tctggttaac cttttgtagc tggacgatat tttctgttga tatccgatcc caaaagcgag
    26101 aaatggatga ctgtgaagcc aaccgctttt tgcttaaaac agcttgaaag ataggatccg
    26161 ttgctaatat attggctgaa gaatctgtag gatagcctgc aatcaactgc aagatgattt
    26221 gttccagaat agattcattt tcatgaacat gatacagtcg gtcatcttga atctggatgt
    26281 ttttacataa gatttggcta aactcaaatt tgttcatgaa ttcttttgct aatattaagc
    26341 cggaatctga ggacaaattt ccaccagagt gagatactgt aacatttgaa ttgaaaagta
    26401 gacgattttc gtgtaaagtt gccattgaga gaaccccttt ctttggttag gtttagtcac
    26461 tttaaccata gcagattggg gttctttttg tacacccaaa gggtgcgaat aaacgaaaca
    26521 aaatagactg ttataacaag gtttttgaaa cgtttttgaa aaactatgaa ttattcaggt
    26581 tataagcatt tacataataa atgactaaga atttcttaag atgatgattc tttttttatc
    26641 aaagggcttt tcggcatcgc taggaggctg ttaatatttt atagtttcct tttcttcttt
    26701 aaaaatattg cccattagcg gaatacagaa tggctaatta ttcacttctg ataatttcct
    26761 gtataatgaa gccctagata cattagtaat ttcacaaatt tgatttacag tcatatttcc
    26821 ttctttatat agctttaccg cataattcat tcctgcgtga tttttatgat acttctttaa
    26881 tcgaccttta aactttcctt ctttcttagc caattcaatc ccttcacgtt gtctcatccg
    26941 aataagatct cgctctaatt ggttaacacc agccattaca gtaattaaga attggctgta
    27001 tggattatct tctgataaat caagccatgt atcttttagt gattttaaac ttgccttttt
    27061 atctcgtatg ttatcgatta attcaaatag atcttgtgta ctacgagtga ttcgagttaa
    27121 gtctgtaaca taaatgatgt catcttcctg taaatcgtct aacacttttt gaagttgctc
    27181 gcgatccttt gttgctcctg aaactttctc ttcatatata atatccattc cgatctcgtt
    27241 caactgctga aattgtcttg aaggattctg gttagtcgaa ctgacacgaa tataaccgat
    27301 tttccgcaaa atatcacctc atttttgaga caagtcttat gagacgctct taactatgat
    27361 tttatcagtc tactacattt gtatcaatag agtacactct attgatatat aattgaacta
    27421 ataaattgaa aatacagaaa tggaatgata ctgaatgaaa attgcgagag gtagagaatt
    27481 gcttacaccg gaacagagac aggcttttat gcaaatccct gaagatgaat ggatactggg
    27541 gacctacttc actttttcca aacgggattt agaaatagtt aataagcgaa ggagggaaga
    27601 aaaccgttta ggatttgctg ttcaattagc tgttcttcgg tatcccggtt ggccatacac
    27661 tcatatcaaa agcatcccag attcggtcat acaatatata tcgaaacaga ttggtgttag
    27721 tccatcctcg cttgatcatt atcctcaaag ggaaaataca ctttgggatc atttgaaaga
    27781 aattcgaagt gaatacgact ttgtaacttt taccctgagt gaatatcgaa tgacatttaa
    27841 gtaccttcat caattagctt tggaaaatgg tgatgccatt catctactgc atgaatgcat
    27901 agattttcta agaaaaaaca aaattatact gcctgctatc actacacttg aaagaatggt
    27961 gtgggaagca agggcaatgg ctgaaaagaa gctatttaat acggttagta aatctctaac
    28021 aaatgagcaa aaagaaaagc ttgaagggat tattacctcg cagcatccat ccgaatccaa
    28081 taaaacgata ttgggttggt taaaagagcc accgggtcat ccttcacccg aaacttttct
    28141 aaaaataata gaacgactcg aatacatacg aggaatggat ttagaaacag tgcaaattag
    28201 tcatttgcac cgtaaccgcc tgttgcagct gtctcgctta ggctcaagat acgagccgta
    28261 tgcattccgt gactttcaag aaaataaacg ttattcgata ttaaccatct atttattaca
    28321 acttactcag gagctaacgg ataaagcgtt tgaaattcat gataggcaaa tacttagttt
    28381 gttatcaaaa ggtcgtaagg ctcaagagga aatccagaaa caaaacggta aaaagctaaa
    28441 tgagaaagtt atacacttta cgaacatcgg acaagcatta attaaagcaa gagaggaaaa
    28501 attagacgtt tttaaggttt tagaatcggt tattgaatgg aatacctttg tctcttcagt
    28561 agaagaggct caggaacttg cacgtcctgc cgactatgat tatttagact tactgcaaaa
    28621 acggttttat tcactaagaa aatatacgcc aacgctatta agagtattgg aatttcattc
    28681 tacaaaggca aatgagccac ttttacaagc tgttgagatt atccgaggaa tgaacgaatc
    28741 tggaaagcga aaagtgcctg atgactcacc tgtggatttt atttcaaaac gatggaaaag
    28801 acatttatac gaggatgatg gtacaacaat taatcgtcat tactatgaaa tggctgtttt
    28861 aacagaactt cgggagcatg ttcgggcagg agatgtttcc attgttggca gcagacaata
    28921 tagggatttt gaggaatatt tgttttcgga agatacatgg aatcaatcga aggggaatac
    28981 gagattatca gttagtttat cattcgaaga ttatataacg gagagaacca gcagctttaa
    29041 tgaaaggtta aagtggttag ctgccaattc caataagtta gatggggttt ctcttgaaaa
    29101 aggaaagcta tcacttgcac gcttagaaaa agatgttcca gaagaagcaa aaaaatttag
    29161 tgcaagcctt tatcagatgc taccaagaat aaaattaact gatttactca tggatgtggc
    29221 ccatataaca ggatttcatg agcaattcac tcatgcttcc aataatcgaa aaccagataa
    29281 ggaagaaaca atcattatca tggctgccct tttaggaatg ggaatgaata ttggcttgag
    29341 caagatggcc gaagccacac ccggacttac atataagcaa ctagccaatg tatctcaatg
    29401 gcgcatgtat gaagatgcca tgaataaagc ccaagccata ttagtaaact ttcatcataa
    29461 attacaattg cctttctatt ggggcgacgg tacaacatct tcgtcagatg gtatgagaat
    29521 gcagctaggt gtttcatcac tacatgcaga tgcaaatcca cattatggaa ctggaaaagg
    29581 agccaccatc taccgattta caagtgatca attctcttct tactacacaa agattattca
    29641 tactaattca agagatgcga ttcatgtttt ggatggtttg ttacatcatg agacggatct
    29701 aaacatagag gaacattata cagacactgc cggttacact gaccaaatat tcggactgac
    29761 tcatttatta ggatttaaat ttgccccaag aataagggat ttatcggact caaaattatt
    29821 tacgatagat aaagcaagtg agtatccaaa actagaagcc attttacgtg gacaaataaa
    29881 tacaaaggtc attaaagaaa attatgagga tgttttgcga ttagctcatt ctataaggga
    29941 gggaacagtt tcagcatccc ttattatggg gaagctaggt tcctattcaa gacaaaacag
    30001 cttagctaca gccttacgtg agatgggccg aatagaaaaa acgatcttta ttttgaatta
    30061 tatatcggat gaatcattaa gaagaaaaat acaaagagga ttgaataaag gagaagccat
    30121 gaatggattg gcaagagcta ttttcttcgg aaaacaaggt gagcttagag aacgcaccat
    30181 acagcatcaa ttgcaaagag ccagtgcttt aaacataatt atcaatgcta taagtatttg
    30241 gaatactctc cacctaacaa cagcagttga atataaaaaa cggacaggta gctttaatga
    30301 agatttgtta caccatatgt cgcccttagg ttgggaacat attaatttac taggagaata
    30361 ccattttaac tcagagaaag tagtctcatt aaattcttta agaccactaa aactttctta
    30421 acgttgttaa aaacgaggga ttcgtcagga aaataggctt agcgttgtaa atccgcattt
    30481 tcctgacgct acccctttat attcttagaa attagtatgt aataagtagt caacaatgtt
    30541 ttctgctaat tcaatttgct tgtctctagc ttttatttgt ttcatcatat caatcgtaat
    30601 gattttatag atacttgctc cacgaaatat ttcttcattt ctcaacaaat ggggattgaa
    30661 ttgtagttgc ttttcttgta aagttgacat tgagcacacc tcttgttttt gttgttttga
    30721 tcgactttac aataacatag agtgtgctct ttttgtatat ttttttcttc acccaacggg
    30781 tgaagaagga atagagtgat aaaccttatc aaagcgggat aaatgcctgt tctgacaagg
    30841 tactatgaat tattcagggt aattccattt ataattaata tcgtaataat taatccagta
    30901 atcccaacac tagttgcact atatatccaa agttttgctc gattaaactt tagtgcttta
    30961 gcaataacac ctattgtcca aacacctgct aaaggagtta acaaaagtat aacccatgca
    31021 ccatgctttt ctatgcgatt ctcccatttt ccatttagac ttttttccat gatttttttc
    31081 atgaaattaa atttcattaa ccattcatag catatatcca caaacggaat aaccatccaa
    31141 tttcctagtg aagcccataa aaaagcgtca aaccaattta gcccggctgc aaaacctgca
    31201 ggtattgcaa tataaatttc aaaataagga aaaaaaccta tgaaccaagt tgaaaatgct
    31261 gctccaatat acttaataat ttccaaaatt aaacctccaa tcaagtttat ttaattttta
    31321 actgcaaaca cctttccaaa aatatctcca taaatgattc aatttttcat tacaattttg
    31381 atttgctaat gaatcaatat ataagttttc caacaacata cgatatacac ttatggcaga
    31441 cgttatctct tcttctgcca acattttttg tttagcacaa tcaataaaaa ttcgtgatac
    31501 tgtgtcgtca ataaaattat catattttgc taataattta tctacaagcg acaacaattc
    31561 actgctagat aaaattgcaa cgcgcttgct gaaagctatc tcatcagcgg ttaaaaaatc
    31621 actttctaga cagacagttt taagcaaaat aaaaagttgt tcatctaatg gtttatccct
    31681 ctctacttca agcaattgtt ttatagcaac gatacattta tctagtattt tttcacaggc
    31741 aatagtaaat atttcatttt ttccactata gtgggtataa atagaacctt tctttatgcc
    31801 aacttgcttt gctagatagt caacagaagt tccttcaaat ccattttcac caaaggattt
    31861 tataaattct tcaataatta aatcttttgt tttcataatt caccatcctt aatactaact
    31921 accggtagtt agtattttat actaggtgat tccatttgtc aagtaatagt ggtgatttgt
    31981 atgtgtcaat actttggcgg aaacttttct ctagagatgg taactcttca attttaatat
    32041 taaaattgct cattctgtgt gtttcgttac ccaaacattt tcttcagttg tcccattgga
    32101 cttgatgtgg aactataatt agctatttca cccattttaa cccctataga aggacgatga
    32161 atctttttca aaacagctct aacagcccct ttaaattcag ggacaatggt ttgttcaaat
    32221 gcaggtagtt ccgctctcaa agcttctaaa agagttccgt ttttacgagc taaaataatt
    32281 tttaatgaaa agctccataa aaagaggaag ccacgattta attcaagtgc attcagcaaa
    32341 gctatgttat acgatagttt caattcgtat caaataacag accgagacaa aacaggcaac
    32401 tatggtgtag atttttccac acttattaag aaattggaaa agagtaactt ataggccctt
    32461 ttccaccata aaatccgaat accctttatt ttttttattt taatatccac tttaaaactt
    32521 cctttctgac aaacttacaa gccttaattg gcttgtaagt attttttttc ttctttatct
    32581 tccttcacct tttgacttcc atacattccc cttattgtgt ccatatcata attttttcga
    32641 ctacgttttt tataatcgct tggtgcttta taccatgcgt atttttttgg tgaataacga
    32701 aattctaggg cttttatgtc gtccttataa ggttttgtgt tgcctgttaa ccatataaaa
    32761 gttcccacga tttcaattga tacaccgtcc attttcagat tgaaaagttg atttataatg
    32821 tccttaaatt gttcgggcgt ttcagtcgtt tcttttgtat aggtttcgcc gtctttgttc
    32881 ttatgagtgt tttttagctt gacaaacaat tcatcatatt cattgtttag ttgcgccatt
    32941 tcttcattgc taccaccaca atcggggtgc aatttcaaag ctaacttttt gtaggctttt
    33001 ttcaattctt ctaatgtttc aacgttttta atgtatttca ttttcatcat tccttttctt
    33061 tttgattttt ggcttttttt tacatttctt taattttcaa attttttatt tcccactcaa
    33121 accattcgct aaaatcttgt ttaaagccgt taatagaata ttgctcttgt tcttctgctt
    33181 ctttatcgtt ttgagggtct aagtaggtcg gtttatcttt tggtcttgcg tatacaccta
    33241 tccatgtttt aaaatcgccc tcaaaactgc tatctatgat aaagccttgc tcttttagct
    33301 cttctcttac ttgagctttt agatattgct gttcttgtgt tccaaaaaac tcattttctg
    33361 taaaatcttc taattgtaat ttttttgttt tttccatttt cttttcctct tttctttttt
    33421 ttgattttta gttttttgac aaccattttt gttaggcgtt tgaggaagtg aagctgtttt
    33481 cctcatgttt taaaagctag aaataaatta cagtgtatgc tcctttcttt tttcagttgg
    33541 ttcattttcg ccagtgtgtt cgtgtcgttt gctgtgacga gaacgcaaca tagacacaaa
    33601 gaaaacacaa gggcgagctt gctcgtttat atacccttgt gttttcgact ggatatgtta
    33661 aggtaacaaa cagtaaatga cacgttacag actgcaaaat gtaccaactg aaaaaagaaa
    33721 gaataccgtt gtgtgcttta tttctcgatc agcttttcaa acatgaggaa aggtttttat
    33781 aaaaaaagag tagttaccgt tttttggtaa ctactctttt ccttttttaa ggtttaaagt
    33841 cctggaagtt taggtgtttt gggtattggt ggtataggtg gctgcaagct ttccaatttt
    33901 tgttgaattg ctttaaattc aggggtttct tggtgttgat tttgaaccat tttttgctct
    33961 attctctcca aagtcggttg aatttctttc cctgatactt tacgatttaa ttctctttct
    34021 aaggtctctt tcgcactaat ggaaggcgtt tctaagcttg aatagagttt cactccttct
    34081 ctattgtaaa gccttatatc gctaaataag cccgttttat gaagggtttc taaattggtc
    34141 ggtaagtttt tgacaacaat atcatgcgct tgttttggtg ttgccctagc tgtcattgga
    34201 tcatctgcat acatggtttc atatcgttca attgttccta aatatgagtt gattttaggt
    34261 actgccatga catacatttt tgtttcataa cctttggctt gaagcattgt tgcggtttga
    34321 ataggaacgt ctgttgttcg tcctgtacct tcgatcacca aattataccc ttgatcgctc
    34381 aaacggctta tgatcgcttc tgtcatgcga ttagaatagg gggtaacgtg ttttactacg
    34441 tctttttcat aaagtttcac tagttcatca aaattagggt gctgttgttt aaaggtatca
    34501 ttatcaatga caataacatt cccttgtgtt tcttcaa
//
LOCUS       DAXQKX010000026        34210 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.026, whole genome shotgun sequence.
ACCESSION   DAXQKX010000026 DAXQKX010000000
VERSION     DAXQKX010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34210
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.026"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     misc_binding    complement(38..276)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(319..552)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(629..1300)
                     /locus_tag="ACF3MF_001391"
     CDS             complement(629..1300)
                     /locus_tag="ACF3MF_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFE3927394.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(1387..4035)
                     /gene="mgtA"
                     /locus_tag="ACF3MF_001392"
     CDS             complement(1387..4035)
                     /gene="mgtA"
                     /locus_tag="ACF3MF_001392"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015444 - P-type magnesium transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HFE3927395.1"
                     /translation="MEKKKDTQKIYAAFAGKTKQELFELFHASANGLTEEQIERSREN
                     YGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPGDKDLFGVAII
                     FTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEEIVCGDLVRLS
                     AGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSYENLVFMGSNV
                     ISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKFMSLMAPAVIV
                     INGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGTVIKNLNAIQN
                     FGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQTGLKNLLDVAI
                     IDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGAIEEMLNISKF
                     IDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFSVKDESDMVLI
                     GYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLEINELVTGEKI
                     SEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGINDAPAMKVADI
                     GISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKATASSNFGNMFS
                     VLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKWNASSIGEFMV
                     YFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAGWFVESLWTQT
                     LVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLMPLPGNYWLWL
                     FATVIAYLALVTAVKKIYIRRFQELL"
     regulatory      complement(4377..4551)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            4724..5161
                     /gene="ndk"
                     /locus_tag="ACF3MF_001393"
     CDS             4724..5161
                     /gene="ndk"
                     /locus_tag="ACF3MF_001393"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HFE3927396.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(5183..6049)
                     /locus_tag="ACF3MF_001394"
     CDS             complement(5183..6049)
                     /locus_tag="ACF3MF_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFE3927397.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(6209..8302)
                     /locus_tag="ACF3MF_001395"
     CDS             complement(6209..8302)
                     /locus_tag="ACF3MF_001395"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFE3927398.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(9052..9675)
                     /locus_tag="ACF3MF_001396"
     CDS             complement(9052..9675)
                     /locus_tag="ACF3MF_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927399.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(9834..11231)
                     /locus_tag="ACF3MF_001397"
     CDS             complement(9834..11231)
                     /locus_tag="ACF3MF_001397"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFE3927400.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(11263..12234)
                     /locus_tag="ACF3MF_001398"
     CDS             complement(11263..12234)
                     /locus_tag="ACF3MF_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFE3927401.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            12608..13033
                     /locus_tag="ACF3MF_001399"
     CDS             12608..13033
                     /locus_tag="ACF3MF_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927402.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            complement(13521..14222)
                     /locus_tag="ACF3MF_001400"
     CDS             complement(13521..14222)
                     /locus_tag="ACF3MF_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFE3927403.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(14238..14678)
                     /locus_tag="ACF3MF_001401"
     CDS             complement(14238..14678)
                     /locus_tag="ACF3MF_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HFE3927404.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(14678..15253)
                     /locus_tag="ACF3MF_001402"
     CDS             complement(14678..15253)
                     /locus_tag="ACF3MF_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0009691 - cytokinin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HFE3927405.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            15494..15703
                     /locus_tag="ACF3MF_001403"
     CDS             15494..15703
                     /locus_tag="ACF3MF_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit beta"
                     /protein_id="HFE3927406.1"
                     /translation="MYYFKQQILVSFINEKIILFSCYVSLINDVSLNKKADELNDQNL
                     IIFVHQLLLKIFLLTINSWICKNIT"
     gene            complement(16101..16613)
                     /locus_tag="ACF3MF_001404"
                     /pseudo
     CDS             complement(16101..16613)
                     /locus_tag="ACF3MF_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014566402.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(16739..17440)
                     /locus_tag="ACF3MF_001405"
     CDS             complement(16739..17440)
                     /locus_tag="ACF3MF_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFE3927407.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(17548..18991)
                     /locus_tag="ACF3MF_001406"
                     /pseudo
     CDS             complement(17548..18991)
                     /locus_tag="ACF3MF_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738852.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
     gene            complement(19005..20870)
                     /locus_tag="ACF3MF_001407"
     CDS             complement(19005..20870)
                     /locus_tag="ACF3MF_001407"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFE3927408.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            complement(20991..21842)
                     /gene="licT"
                     /locus_tag="ACF3MF_001408"
     CDS             complement(20991..21842)
                     /gene="licT"
                     /locus_tag="ACF3MF_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HFE3927409.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
     gene            complement(22152..22865)
                     /locus_tag="ACF3MF_001409"
     CDS             complement(22152..22865)
                     /locus_tag="ACF3MF_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HFE3927410.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            complement(22933..23259)
                     /locus_tag="ACF3MF_001410"
     CDS             complement(22933..23259)
                     /locus_tag="ACF3MF_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HFE3927411.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            complement(23382..23609)
                     /locus_tag="ACF3MF_001411"
     CDS             complement(23382..23609)
                     /locus_tag="ACF3MF_001411"
                     /inference="COORDINATES: protein motif:HMM:NF013777.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFE3927412.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            complement(23931..25184)
                     /locus_tag="ACF3MF_001412"
     CDS             complement(23931..25184)
                     /locus_tag="ACF3MF_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFE3927413.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYGNAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            25245..25985
                     /locus_tag="ACF3MF_001413"
     CDS             25245..25985
                     /locus_tag="ACF3MF_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFE3927414.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            complement(26071..26829)
                     /locus_tag="ACF3MF_001414"
     CDS             complement(26071..26829)
                     /locus_tag="ACF3MF_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFE3927415.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(26826..27290)
                     /locus_tag="ACF3MF_001415"
                     /pseudo
     CDS             complement(26826..27290)
                     /locus_tag="ACF3MF_001415"
                     /inference="COORDINATES: protein motif:HMM:NF023225.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
     gene            complement(27309..27806)
                     /locus_tag="ACF3MF_001416"
     CDS             complement(27309..27806)
                     /locus_tag="ACF3MF_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HFE3927416.1"
                     /translation="MILLLGFILWQTPVHASEFNFAVDFELPANQIDKNKTYINVRME
                     PGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESKSKFDETLSYDMKNLAK
                     TVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKENVSNKSTVGVVNQFSQV
                     KAILI"
     gene            complement(27874..31041)
                     /locus_tag="ACF3MF_001417"
     CDS             complement(27874..31041)
                     /locus_tag="ACF3MF_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HFE3927417.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVDVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            complement(31265..32149)
                     /locus_tag="ACF3MF_001418"
     CDS             complement(31265..32149)
                     /locus_tag="ACF3MF_001418"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFE3927418.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(32244..32681)
                     /locus_tag="ACF3MF_001419"
     CDS             complement(32244..32681)
                     /locus_tag="ACF3MF_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927419.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            complement(32898..33809)
                     /locus_tag="ACF3MF_001420"
     CDS             complement(32898..33809)
                     /locus_tag="ACF3MF_001420"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFE3927420.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
BASE COUNT         9766 a         7230 c         5673 g        11541 t
ORIGIN      
        1 aaaaaaagcg tcctcaagaa aatgaaaatg tcattttctt gaggacgctt ttttgcgtgt
       61 taccacctca tgttcaagct gtgttcacac acaactcctc ttcaagtacg atcatactct
      121 agcaagatat cggtcgcagc cgtcatcgcc ttacatctat gctcgggatg aattgctcga
      181 tggccatttt ccaatagtcg ttccttgctt cttctcagct accgaagctc tctgtcaaag
      241 gttcttctat cgtacttacc atttcaatgc aaataatatt caaaaaaaaa gtccttttac
      301 taacataaac tatgtcagta aaaggacgac gtatcgcggt accacctttt ttcggaagtt
      361 tccttccctc aagcccaaca tctcaaaaag agagattggc gttcgtttta acggtcgaac
      421 agttccgaat ttgcctactt atcgacaaat tattctccaa ggccattttc agcttttctt
      481 acttgactct tctcaccagc cagagcctct ctgcaaagtt tccaaactta ctttcctttt
      541 caacgaaatc gatattttgt tgttgggatt aatctacatg aggaaaactg aaaagtcaag
      601 tacgaaattc aaattatttt ttctatattt atttttctgt ttttttattt aacatttcaa
      661 taacagttcg aagatctttt ccttccgcaa gaagtttcaa tttttccttt tcttcgacgg
      721 tataatttcg gacaaaactg gaatcaggta tcaaaacaac gcctaatcct gctcgtgaag
      781 cagctgttgc tcctactaaa gaatcttcca ctgcaaaggc tgaactagct tctaatcctg
      841 ttcgttccaa agctgtcaga taaggaatcg gtgaaggctt gttctccgac acttcgtctc
      901 cgaatgtaaa cgtgtccaag taatcagcta atttaaagtg atccaagata tctgttgctc
      961 ttttcgtaac agtggtcgta gcaatgccta gtttcatatg acgttctttt aagtctgcca
     1021 atatttcttt tgcatatggt tttaagtgga tggctccgct tgtcagctgt tgataaaaat
     1081 attcttcacg cttcgctcgg acttcctgta ctttttcagg gctacctgct gctttcacta
     1141 aaatatcaaa actttgtttc cagttttttc cgccccaagc gtcaacgatt tcttttggga
     1201 tatggatatc aaattgctga aatccccaaa gccagccatc acgatacgtt ttttctgtgt
     1261 caactaacaa accatctaaa tcaaatattg cacctttcat ctatacatta atcctttcca
     1321 aaacaataca catagtttag cacgactggt ccaaaaagaa cagaagcaaa gaaccagcct
     1381 tctcgtttat aagagttctt ggaatcgacg gatatagatt ttcttcacag ctgtcacaag
     1441 cgccagataa gcgatgactg tagcaaataa ccataaccag taattgccag gaagtggcat
     1501 caagcctaat tcagcaccaa aacttgtaaa aggaaggaca gaaccgacaa taattcctaa
     1561 tgtagtgata acaaacatgg caaatgttgc gttgctttgg ataaatggta ctttcggtgt
     1621 acgcagtgca tggagcacta aggtttgtgt ccatagtgat tcgacaaacc atcctgcatg
     1681 gaataatgcg atgaaaatca ctcgctgtga actatccaat gtatggaaac ttccgcccac
     1741 tacagcagga caaataacaa aatacatcaa caagtaagta gtaatatcaa atatcgaact
     1801 tgttggacca aagtaaacca tgaattcccc aatactagat gcattccatt tttttggctc
     1861 gtccaaatat tctttatcca tccgatccca tggcaaggaa atgcaggaaa catcatagat
     1921 cagattcaaa aacaaaagtt gtaaaggcag cattggtaaa aatggcagga acgtacttgc
     1981 aatcagcacg gaaaacatat tgccaaaatt agaacttgct gtagccttga tatatttcat
     2041 gatattccca aaagtttctc gtccagaaag aaggcctctt tccaaaatcg tcaaatcttt
     2101 ttctaaaagg atcacgtctg cagattcttt cgcaatatcc acagctgtat ctacagaaat
     2161 accgatatca gccactttca ttgcaggagc gtcattgata ccatctccta aaaatccgac
     2221 agtatgacca tttttacgta aagctgtcgt caaacgtgct ttttgctgag gattcaattt
     2281 tacgaatact tcatggtctt cagctacttg tgctaattca tgatcactca tttccgagat
     2341 tttctcaccg gtaaccaatt cattgatctc tagacctact tgacggcaca ctgaacgtgt
     2401 aactaattcg ttgtccccag tcagaacttt tacagctaca ccatgttctt tcagagcttt
     2461 caacgcttgt ttcgttgttt cttttggtgg atcaaggaaa gcaagataac caatcaaaac
     2521 catgtctgac tcatctttga ctgaaaattc tccaacgacg cttggattgg tcttttgtgc
     2581 gacaccaatc actcgtaagc catcttcatt aagtgactgt acttttgcaa gtacggcttc
     2641 ttttcgttct tttgttaatg gtgtaacagt accgccaaga tcaataaatt tagaaatgtt
     2701 cagcatttct tcaatcgcgc cttttgtgat catttgtgtt ttaccagctg gatcagcaac
     2761 cacaacactc atacgacgac gttcaaaatc aaaaggaatt tcatccactt tttgataatt
     2821 gatcttatct gtatctaaag tttctgttgc ttcatcaatg atagccacat ctaacaaatt
     2881 tttcagccct gtttgatagt agctatttag atacgcatgg cgcaaaacac gatcatcttc
     2941 atttccttca caatccatat gatattcaag aatgatttta tcttgtgtca atgtccccgt
     3001 tttatccgta cataacacat cgattgcacc aaagttctgg atggcattca aatttttgat
     3061 cactgttcct tttttggcca tcacacttgc tcctttgacc aaattcgtcg taacgatcat
     3121 tggaagcatt tcaggtgtta gaccaactgc tacagatagt ccaaaaagaa aagcttctag
     3181 ccaatcccct tttgtaagcc cattgatgac gataactgct ggagccatca atgacataaa
     3241 tttgatcagt agcatggatg ttttatggat gcctaattca aagcttgatt gaattggttt
     3301 ttcagatagc gtttctgcta catgaccaaa tagtgtttca tttccaacag aaacaatgat
     3361 tccttccgca cttccactga tgacattact tcccataaag acaagatttt cgtaacttgt
     3421 ttcgctttgc tgatcgtctt cacatacttt cgcatgcttt tctactggat agctttcccc
     3481 tgtcaatgct gcttgggaaa tgaataaatc ctttgcggac aataaacgca tatccgctgg
     3541 tatcatatcc cctgctgaaa gccgaacaag atctccacag acgatttctt ccataggaat
     3601 ctctgtgtac tttccattac gttttacagc tgccgttact ttcacaagtg atttcagttt
     3661 ttcagccgct tgattggaac gtacggactg aatcaacgtc attgtcccgc tgacgataac
     3721 catagtgaag ataatggcta caccgaaaag atctttatct ccaggagctg ctaatacata
     3781 ttccgtgatg aatgaaataa ttcctaatgc gatcaacact aatgtaaatg gcgtgatgta
     3841 tgctttcaat atttctacaa tgaatggtgt ttttttgcca tatgaaatcg cattttcacc
     3901 gtaattttct cttgaacgtt cgatttgttc ttctgtcaat ccatttgctg atgcatggaa
     3961 tagttcaaat aattcttgtt tcgtttttcc agcaaaagct gcatagattt tttgtgtatc
     4021 tttctttttt tccatctcaa tctctccttt gtgtccaaaa gacagctgtt ctcgctgctt
     4081 ttggtcttta gctattcatc ggatcgatag agaaaaaact gaaaggggct gagaacagat
     4141 agataatagc cctggccttt cctctagatc cttgtttttc gaatgactgt catccatttg
     4201 ttctcatctc ctttactaag taattttaat tcatgacttc caatcatttt tcgaatagtt
     4261 atttttccaa ttagaccacc tcctttttat ttttcaccga tggggatttg cggcaacaaa
     4321 aaaacctctc gccaaatact cagcgaaagg tttgaaaaag catattaaaa aaagcttctc
     4381 agatctcatc gttgagtttt gacactgtac aacgtaaaaa gcagatacct gcttttagct
     4441 accttatgaa aagccttatc tcgacaattc ctgttctacc cattggcgtc tctcgacgtt
     4501 tttgggcagt agcctatgtt tgtataggag cctcacctaa caaatcttat tcggttttcc
     4561 ttcgttaata taacaactaa aaaagaggat gtcaaatcaa ttttccatgt ttttcatact
     4621 ttttttaaaa tacacacgtt atattcctgt ctcacgcggt tttatttgtc tcattttcca
     4681 cctcccgcta taatagaaat atagtaggaa acgaggtgct gttatggaaa gaacacttgt
     4741 tattatcaag ccagacggcg tgagacgcca tttagtcgga agcatcatcc aacgttttga
     4801 agcaaaggga ctggccattg ctgaaatgaa gtttgaaact atgactcctg aattagcaaa
     4861 agaacattat cagcacttga ctgagcgcag tttttttgat gaactgatcg attacatgac
     4921 ttccggtcct gtcgtttatc ttgtgctggt cggcgaggaa gtgatcgata tcgtccgtaa
     4981 gatggttgga gcaacaaaag ctgccgatgc tgttccaggt acgatccgag gagactacgc
     5041 gctgccgggg actgaaaaca tcattcacgc ttctgattcc cgtgatgctg cggtaaaaga
     5101 gatcgcccgc tttttcccgc cattcgatat aaacaaaccg tctgaaaaag cggcgaagtg
     5161 atacaaattc taaactgctg gtctagttgc tgggttcagc aatggccagc agttttttct
     5221 ctaaggacct ccgttgattc tttcctaaca tatattcgag cactgtgaag aattcttggt
     5281 agtctttcgt cttttcttcc cctaaagcag cagaaatcaa tctttgataa taatctgcca
     5341 tcaatgtttc atagatcact gtacttcttt ctttatgtgc taagctccgt ttcatatctt
     5401 cattcacact acgtgccttt ttcaaccgac cattttctat ataaaacgaa gtcaggttca
     5461 ttaaaaaagt aaagagatac tgctcatgat tgttcaactg tgctaatcgt cgcattcttt
     5521 ttttgatttt caaataattg ttctcaatga accgatcact gaatatccaa ggaaaatcag
     5581 ctagaataga tagttcaaat tgaccatagt ctggtatctg catcaagtat tcttcaatga
     5641 ttcggcattc ataacgtaaa aattcaaatt ctgtctcaga tacttctgtt ttttcgacca
     5701 tgtgaagatt caaaaccaaa taatacagat cttctgtttt cttaaaatgc ctacggttat
     5761 tgctgatctc tttataagga tcaaagctgt cttcttgtac ccgatctagc attcgtcttt
     5821 ttttctttaa ctttattggt tcatccagct ggtttcgcat ccattcatat tctgcaagtg
     5881 tcatgttcat tcgctctaaa aatgatctca atgttacaaa tgacattttt ttcactgaat
     5941 ttgtctcaat cccgactaga gaagtcttaa aacagattcc ttccgctaat tgggactgtg
     6001 tcaacttctt gttgactcga agtttcttga tcaattcacc atcatacata atagttctcc
     6061 tttttaattt aaatttttcc acattcaata aatagatacg ttaaaaagga aaaatacacg
     6121 aaaaaaataa aaaaatgttt ttttcataaa aaataccaac cttcaagcat tagaatgttg
     6181 tctaactact gaaggttggt ttgattgttt attgattatt tttttgctgt tcaacgtctg
     6241 ttcttgttac tggatataag ttggttgttg ttttattacc attttttgaa aagacacttg
     6301 tcgaatgttc gcctttttgc ttttcgattg cttcattacg ttccgcttca tttttatagt
     6361 catatttttt cggatcaatc gtctcaaatc cgtttggcac ataaaaccgc aagagatttt
     6421 cctgattcag cttatctgaa agacttaacg cagtcttgac tttttcctga tctttggaga
     6481 tttcctcatc gattcctgct gctttcgtat cgatgatttc tcctgtctga ttattgtaag
     6541 cttttcctcc taggacggtg tatttgggtg tcacaaagtt cccatttcga aaagcaacta
     6601 cttgatcatg ctgagaagat aataagtctg taccaaaatg aagataatct ttatcatcga
     6661 ttcccaatag atgtagtaat gtcggcaaaa catcgatttc tccaccgtat tcatgattga
     6721 ctgtcccttt agtataacca ggcatatgga tcatcaatgg cactcgttgc atctgtgcgt
     6781 tgtcaaattc atcccatgta tctggatctt taccaagagc gcttgctaaa tctttattat
     6841 ctgtattcga gatcccaaaa tgatccccgt aaatcacaaa gattgaattt tggtaaatac
     6901 cagatttttt caaatacgta aaaaattgtt ccaatgattg atccagataa tgtgccgttc
     6961 gaacataatt atctactgtg ctattgccag tattcaaaga tggaaagtcg aaattcttgt
     7021 catccgtata ataaggcgtg tggttggtta cggaaagaaa tttcgtgtaa aacggctgtt
     7081 gtagatgctc aagatattgg gcagattctc tgaataaatc tttatctaat atcccataac
     7141 ctaacgtttc gtcggattca tcaaaataag atcgatcaaa gaaattgtca taacctaagt
     7201 ttttatatac atgatctcta ttccaaaaac tagctacatt cccatggaaa acagcgcttg
     7261 tatagccttg cttttgtcca aggatcgctg gtgcggcttg aaagacattg tctgacccaa
     7321 gttctgtgaa taatgagcct tgaggtaaac caaatgtgcc agtttccaac atattttcag
     7381 catcacttgt ctttccctgt cctacttcat gaaagaaatt gtcaaagctg atcgttgctt
     7441 gattctggaa aatactattt aaaaacggtg tgacttcttg tccgtctacc ttcatattaa
     7501 tcaaaaactg ctggaaactt tctaaatgga gaacgatcac atttttccct ttagcgatcc
     7561 caaatgtttc gggatttggc tctgcataat gtttctttgt ataatctaaa acttcatcaa
     7621 tcccattact gcttgcatgc gcgcgaacac tgctagtcat tcctgttttg attccgtcat
     7681 aaatagtata cgcatcgatt cctagatatt tgacaatata tgaacggtca aatgttcgct
     7741 gcagcaattg tggacggttg gcttcgctca gcgctagatt tcctgaaaaa ataagccctg
     7801 aaagacaggt aacagcgata gccatcggtt tgccgacagg gttgcttttg ataggtattt
     7861 tcttgacctt caaccaaacc agtagcccaa tgaacacagc gatatccagc cagtagatga
     7921 catcatgggg cttcatcaaa gaaaaggagc ttcctgacaa tccttgcgac actttcgaaa
     7981 agcctaatac agatttgact gtaatgaaat ctgtgaattc ccgataaaaa ataatattca
     8041 agtacaacaa aagcgtattt aaaatatcaa tgatcaaaag aatagctaac gctggctttg
     8101 gctttttaat atacaaagaa aggccaaaaa acaataaggt agtcgcaatt gggttgatcc
     8161 acaagataaa gtactggatc gtaccttcca cacctaatga aaaatctgca tagtaggcaa
     8221 tgatcgtctt cagccagaaa aagaaaacag ctgtcaaaac gattgctaaa cgattttggc
     8281 acaatttttt aagttgtgtc acgtatatca cttctctcta ttcacatttt ttcttatttt
     8341 gctcctgaaa aatgaaaatt tcctaaaaaa gttgttatct taagattttt ttattctttc
     8401 taaagattat tccgtccact tttcacagca taaaaccgct gcgatgtaag cgattaaact
     8461 aatgaagaga taaaagtctt gtggtgaccg cttcactcca cggtattcaa aagccagttt
     8521 ctcggtattc gtacaaaaaa agaggctgtg acaaaattct tgtcgcagct ccttatttct
     8581 tgatgcagga cagctttttc acaacttctt ccttaaacgg tgttctcctg ccaactcctc
     8641 ggccacaagt cacaatattt ataaaacatg agaagctgtt tttttgaaat tgttccttgt
     8701 ggctcagagt taaacggcag gctcaagacc tcttgataca cggtgttcaa tcagctgacc
     8761 ctcggtatta gattatgtca ggacgctaat tttacaacct cttggtaaac ggtgttcaaa
     8821 agcttgcatc tgcggtaata agcccaacca aacgaaaaat ataaggagct attttttgaa
     8881 attgctcctt gtggctcaga gttaaacggc aggctcaaga cctcttgata cacggtgttc
     8941 aatcagctga ccttcggtat tagctcaaaa aacggcaaaa tatgaggaac tattttgccg
     9001 tttgtttctc taatactcag gtcaaaacgc tgatttcaca acctctgttt ttcattgtcc
     9061 ataggattga tattgtcctt gtgatgactc attcgtaata attgaggctt gattttcttc
     9121 acttcccgtt atcgtttgtc cactgccaga atctgaagga cttgttcctg tcgactcgtt
     9181 tttttgagaa gagacagttg ttttcttgac ttgttcattt gtctttttcc attccgctaa
     9241 acgatcggcg accacttttt tgtctacttt ttcagaataa gcggtgatca cttttccatt
     9301 tttcaaacgg gctactttgt cgccatcatg agtcaaaagc aaaacggtca aatgcttgtc
     9361 tttaaattga tattgtctga gagaaatcgc actaagtacg tcatcgatat taataaattg
     9421 attttcttct tttccttttg gcaaataaat gtccaattcg cctttttcgt aattggcagt
     9481 tattttatac tccgcccacc aataagttga gaattctttt ttgaaattat ctactgattc
     9541 tttgcttgct acgatttttt ctgtttcttt ctgagcaaga tctgctgtca tttttcctga
     9601 aaatgctgcg gataaaataa gcagtaagaa aaaaccgaat aaccaaaaga gaagaaacgg
     9661 tctttttttc ctcatgcttt cctccactcc tatttaattt tgactattct attatataca
     9721 aaaaatgaaa tagaaagaca aaaaagttga aaaagatcgt aaataattga acttcttttt
     9781 cacaaaatgg taagaatgga gaatttcacg catttgctct caactattct ttcttaagcc
     9841 tcaaatccgt ttttatctga tacgtctttg aaccaatgac ccgatttttt gattgttctt
     9901 tttccatctt gtgctaagtc tactgaaata aagccatatc gattcttata tgcattggtc
     9961 cacgaccagt tatccataca tgtccacata tgatagccta aacaattggc accttcttga
    10021 atggcttgat ggacatattt cagatgagat tggacaaatt cgatccgata atcatcgtgg
    10081 atcatgccat cttctttgat aaatcgtgct tcgttttcta cacccatacc gttttcagaa
    10141 ataaagcagt cgatatttcc ataatgatct cgtacattga tcaaaatatc atagattcct
    10201 tgttcataga tctcccatcc gcgataagga ttcattttac gaccaggcat ttcataattg
    10261 tcgaaataat cctcaggcat tggaccgttt ttagtatcga ttggtgtttc ttttgctttt
    10321 acccggcgtg gctggtaata attgatacct aaaagatcta ctgtattttc tttgataacc
    10381 gtcaaatcct ctgcatggat cacaggcatg agatcaagtt cttttactat ctcaatcaat
    10441 tcacttggaa actcgccttt tacagctgga tcaaggaatg aacgattgaa gaacgcatct
    10501 gctatttgcg ctgctttaac atcttcaggg tttgattcgt ctcttggata gcttggtgtc
    10561 agattcaaga tgataccaat aacaccacct tgctccattt catggtaaga tttgatggct
    10621 aacgctgaag ccaacgcttc atgatagcca acttggatcg cttttttcat atctgactct
    10681 tctggataat gccatcgata taaataacct gcttcgactg gaacgattgg ttcattatga
    10741 gtaaaccatt tttttacttt cgaaccaaac aattcaaaac aacttttggc atatttttca
    10801 taggcttcaa ccgtttctcg gttcaaccat ccgccttttt cttgcagata catcggcata
    10861 tcgaaatgat acagattcac aaagggttcg ataccgtttt caatcaactc atcaaaataa
    10921 cgatgataga aacgaacggc ttcttcgttg attgttccag attcatcagg tatcaaacgg
    10981 ctccattgga tagatgttcg aaatgaatta tgcccagtct gtttcatcaa ctgtacatcc
    11041 tcttgatact tcgtataaac ttgcgaggtt ttttcaggtc ctacttgatc aaagaacttt
    11101 tgcggttctt ttttgtacca ataatcaaaa atgttctctc cttttccatc gcctgaaatc
    11161 cttccttctg tttgtgggcc acttgctgca gaaccccacc aaaaatttgc tggaaattga
    11221 tattttttca tcaaagcacc tctttttctt ttttagttcg ttttagttga ttccatgtat
    11281 gatattttcc atcacaatca ctttttcatt ttcttcctct tcttttttga ttcgttttaa
    11341 cagctgttct gctgctcgtt ccccgatttt atctgttggt ggcgtgatcg tgattttcgg
    11401 aaggatactc agatcgtttt tatctaaata atcatagtga ctgaacgcaa tatccttccc
    11461 gattctgaca ccttcttgat tgaaacattc gatggcacca atcgacatat tgtaattgct
    11521 gacaaaaata gcagttgccc ctttttctaa taatgctttt gccccgtaat agccgctttt
    11581 tctagaatag tctcctgtaa agacctctaa ttggatcgat ggatcatttt ggaccgcttc
    11641 tttggctcct gctaaacgtt ctcttgctac gtagtctgtt tgagtggcag caataaatcc
    11701 gattttttta tgtccttgtt caccatgatg agcgatcact tttgctacac tttctcgatc
    11761 attcactaat attgtatcaa tacctgctgg tccttctgga caattcaatg cgataactgg
    11821 aatactcatt tttgtgagca tttcaaatcc agaccactct tcttcggata agaagacaat
    11881 cagcccatcg atcacatgct tcatcaggta ttcaattttt tgttcaattt tttctggctg
    11941 atcggcaaac ccgcttaata ataagctata cccattttct tcagctactc tttcgatccc
    12001 tgagacaact tccgacccaa aacggctgga aatcccgttt atcaaaagtc caatagagaa
    12061 gcttcgatta ttcttcaacc ctttagcaat gatgttttct ttatagtcca acgctgaaat
    12121 cgcttctgct atttttttca tgttcttttc cttcagttgc tgaccattca agtaacggga
    12181 aactgttccc actgaaacac cagccatctt agccacatca cggatcgatg ccatacattc
    12241 tcactcctgc cagttacatt tgatttctct ttcttgttgt tcgattatga tgaccgcatt
    12301 ctttgcatag tgttgcttgt catcaatatc catataacta aagtcttcag tagagcaact
    12361 tcctctcact attaattata cttaaacaag tatttgaacc ggttcatttt taatatagca
    12421 tttttttaaa agattgcaac acttttttaa aacgctttct gaaagtggcg gattttttgc
    12481 ctttttaaaa ttttattcta aaatttactc tatttgtggg tgttttgtgc gtttttctct
    12541 tccatccgtt tgaagtttta cattccaatg gtataatttc tttatcctat caaatggggg
    12601 aagtattttg aagaaattaa tcgtactatt tattttgtct gcgggacttt tgacattgac
    12661 tggctgtgat ttgtttggcg gctctgacca atcctcggac gaaacaaccg attcttctgt
    12721 cttaaaagcg gaaaaagcag ataccaccaa cagtgtatat acgctaaaag tacgtaaaga
    12781 tatggattta tccgcgggac agttgacatt tacagataaa aaaatggaat ggacacgcac
    12841 gtatcagaca caaggaactg attcttctga atcatctgaa gaaaaaacag tgctgacaga
    12901 tatcaagatc actaccaaag atgacgaata tattatttca ggaaaagaaa ataaaaaaga
    12961 aacaacagtc atatttacaa aaatcggtaa ttaccgtttg aaggatgagg atggcaacat
    13021 ctacagtcta tagtgccgtc tgttggatct tcttttgttt ctccccttct tttctgctat
    13081 agtaaagaag caagatgatt gtaaaggaga cgaaatggat gatcgatagt cctgattatt
    13141 gtacatgtaa taacaacaaa aatatccata cagaatttaa tgaccaagga agcttgagca
    13201 tatgcgacaa ctgtcacaaa ctagtcaaag attcatttaa aacatttgaa tcttatcctg
    13261 ttcaaaatta tgtaaaaagt agaagaagat aaacaaatcc aagcaaaact cactatggct
    13321 gatttttatg aacttcaaac tcagcttctt cctttgatca agcttcatca gtaaaacaaa
    13381 cagtggatca tttcagttta caaatcaaag agtaaagatt tatttatttc aaatatttga
    13441 atataaaata accaaacgat agaaaggctt attctacatc acgtagtaat ttttctttcc
    13501 cgtcgtttgg ttttttattt ttagcctaat tcttgacctt ttgcatgctg gttatccgta
    13561 aaatattttc cagcaggctt tccttccaat tcagctaatt tttcttggat ctgacggatc
    13621 accttttttg catcttctgg attttctaca aaatcgaatt tatccccatc cacttgtatt
    13681 ttaggacata catcaaaatc ttcataccat tgattatagc gggtgttcaa cgtttcataa
    13741 taggtatata acgtctcatc gctttctagc tgttcatagt cacgcccacg ttttttgata
    13801 cgttctagca tcgtgtccaa agaaactttg atatggacca tcaaatcagg ccgttttttt
    13861 ggagcaacat catctaactc gtttagcatc gtatctaata agctatcgta ctgctgtact
    13921 tcgatatccg ttacccgacc taaatcagcg tttagatgga acaacaggct atcttcatag
    13981 atggatcggt ctagcacatt gtcatcgttc actaaagcat ttttcattgc taaaaatcgc
    14041 ttgttcaaaa agaagatttg caataaaaaa gcgtactgct caggatttga ataaaagagc
    14101 ggcaatactt cgttatcttc gacattttca taaaatggtt tagaatcaat ctcttttgca
    14161 agcatatccg tcaaactgct cttacctgca ccaatcgttc ctgaaatcaa aatcactgac
    14221 atacaaccct tcctcttcta taagtactcg cctacgtaag tttcaacagg caatgtttca
    14281 aaatcatatt cacgtacagc ttggtctgat tttaaatacg tatggagact ttgtgtaatc
    14341 atcaagttcg taggtaccgt ctcttcttgt acaatgatca tcggtttttt caacatagtt
    14401 gccacaccta attcgtaagc cgttcctgga tcgattgttt gatgctcaaa gtcaaggata
    14461 gcaacaacaa attctgcatt tgtcagttct tccatatctt tttcgtatac ttcctgcgcc
    14521 catccagcgc tgaatagttc ataattgctt tcttggtgat gacgtggaga gtagaaactt
    14581 gtgactgttt tgttttcctc caacgctttt tcgatacgac ttactcgatc gatttgctcc
    14641 tctgaaaaaa atggtcctgc taaatatatt tgactcatta ttttgcctcc ttcaataata
    14701 actgattttt aatagatact gctcgtaatt cattgaccag ttccaatgga ttgttggaaa
    14761 agattacttg atccaaccat tttttatcca taaaatcctc ttttgcaaaa gtttctaata
    14821 attgttgcaa gccgctgtaa taaccgccaa tattcaatat tccgattggc ttgtcgggcg
    14881 tcagaccgat tgctatccaa gaaagaagtt gtgagaattc ctccaatgta cctagacctc
    14941 cagggaaaac gaggacagca tctccctttt caaataataa tacctttctt tcatcgatcg
    15001 tttctgtagg aataaatgta gtaacatctt ttccaggcaa ttcagtttca aaaagcccat
    15061 tcggatagat acctgtgact tttccgttat tttccagtac tgttttacta atcactccca
    15121 taatcccgga gtatgaacca ccgtaaacca gttcgatttc ttcttgtgcc atgtattttc
    15181 ctaacgtttg cgcaataaat ttgtaacttt ctttattacc aaaacgggaa ccgcaaaaaa
    15241 cagtaagttt cataaaaaaa cactccctaa ctcaaaagtc tatcttcatt ctacacgtgt
    15301 ttttttaaaa taaaagacta gattttgtag ttttttagtg gtatatagga tagacgccac
    15361 tatatatagt atttagaaaa aaatcatttt tcagccattt tatagataaa acaaaaataa
    15421 ataacgtgtt ttcatcgata tgaaatgact tacttataga agatactggg atttcgtcct
    15481 atatgccaat aacgtgtatt attttaaaca acaaatactt gtttctttta ttaacgaaaa
    15541 aatcattttg ttctcgtgtt atgtttcact gataaatgat gtttctctaa ataaaaaagc
    15601 cgacgaacta aacgatcaaa atttgatcat ttttgttcat cagcttctcc taaaaatctt
    15661 tttgttaacg ataaatagct ggatttgtaa aaatatcact tgaatcgtca ctgctggaag
    15721 aaaattcagt gataaccgca cctgttgcgc ctgcctggaa ctagtgtttg atattgggct
    15781 cgaacgtgta ctgatctcta gcatgaagaa taatttcttt ttttactgta taataacttt
    15841 ctttcctttt tggaatagta caggaaagtt tttttgtttc ctttccttcg acataaggta
    15901 taccagaccc tttcgacaac gaaaggttct catttttcct tcatcgtcat ttcaaggagg
    15961 gtgccgatgc tctggacagt ttcgatcgct cctaaaccaa aatctgtata ttcgattctt
    16021 tctaactctg attctttcat accattcctg cctcaaggta catctattgt acttttttct
    16081 tgtaatccat tctgcctctc ctaactaatt gtcaaatcat cccaagatat gtcttcttcc
    16141 tctttttctt cttggatgat ttctgcattc ggatctactg gttttttcaa taataaaatg
    16201 gttattcctg tgacaaaaga accagctaac aatgcaccaa tgaatgccca tggtctggtc
    16261 atcgtagcga ctgcaaacat tcccgatgcc ggaatacggc tatctgcgcc ccaaaacatg
    16321 cttaatccgc cacctactgt cccaccgact cccgttgcta tgacattgcg tgccaagtcg
    16381 ttcaatacga tagggaaaca tccctctgtg atctgacaga tccccatagg aaaagcggtc
    16441 ttcaatgtat cgatttcttg acgattgagt atatttttac gaatgatttt ccctaagaaa
    16501 taagcgatcg tcaagccgaa tggggttacc atcgaagcta aaatcaatac agtgattggt
    16561 tcatagattc cttctgaaaa tcgtgccaca cccccttatc cagaataaat ggtaatccag
    16621 aaacagccgt gtatctgcgg taataagcct aaccaaacga aaaatatgag aagctatttt
    16681 tgtttggctg ttcttattac ttgatgcagg gcagcttttt cacaacctct ttttttattt
    16741 atgtttcata atcaatatgg taaggatgca gctccgtatg gtagaccgcc tccgaatatt
    16801 caatcatttc cccaatttgc gtagacgatt tccgtatccg tttgatgccg atctgtgcgt
    16861 ctgttttcag aattccttgt tcttcttctg ttaaaaatac tgccgagaaa tcatcagaaa
    16921 atgagtcaat agtatatcct tttttcgtca gcaaacgata caaagattct ttgccaaatt
    16981 cttctctgct gaattgcatc atttcttgtg gaagataatg aacaaaataa atataaggct
    17041 gattgttcaa ataatataag cgcttaaaac aaacagcttg ctcaccgaaa aaggaaaaca
    17101 aaggatcttc cttctttata tggaccaatt gcaaatccag cgtttctttc cggacttcat
    17161 atcgggagtt ctccaagatt tgcgtaaagc ttgccgcttt ggataatcga ttgtaaggac
    17221 gattgcttag aaccgtcgtc ccacgaccac ttttctttgc gacatattca tctgatgcca
    17281 gcagttcgat tgcctttcgg acagtgattt tgctgacttg aaacagttct tctaattcac
    17341 tttctgtcgg caacatcgaa ccgactggat attttcctga gaaaatatct tctttaattt
    17401 tatctgcgac ttccaagtat agtacacgtg tccttttcat aacgtcaccc tttgctttac
    17461 tattactaaa agaatagcac ataaaaaata aaaaaagaac acaaatcaca tgtgagaagt
    17521 gtgttctttt tcattcagct gctttaatta caagtttacg ccatttgagg caattacttc
    17581 tttataccaa tcaaaagatt ttttctttga tcgattcagt gtcccatttc cttcatcgtc
    17641 tagatccaca tagataaagc cgtaacgttt actcatttct cctgttgatg cactgacaag
    17701 atcgatacat ccccaaggcg tatagcccat caaatctaca ccgtctgcta ctgcattagc
    17761 catcgcttcg atatgacgac gtaaataatc gatccgataa tcatcaataa tcgtgccatc
    17821 ctcttccata tgatcaatgg ctccaagacc gttttcaaca atgaataatg gtttctggta
    17881 acgattgtat aattcattca atgcgattct cagcccttct ggatcgatct gccagcccca
    17941 ttcacttgcc tcaagaaacg gattttttac tcctcccagc aagttccctt ctgaagttgc
    18001 tgcttgtgga tcagtctcat tgattgccgt agacatataa taactaaatc cgatgtagtc
    18061 cactggatat tcttttagca actggaagtc tttttccgtt tgctctaatt tttccggatc
    18121 gactccatat tttttatggg tacgcgctgt gtatgcaggg tattctccac gtacttggac
    18181 atccgtgcag aaaaaattga attcttggtt ttggatcatt gttgctgcct gattgactgg
    18241 attggcatcg atgctgtaag ttgttgcata gataatcatg cagccgattt ggatatccga
    18301 acgcaattcg tggccgattt ttacggcttt gctacttgca acgaattgat tatgccatgc
    18361 ttggaaaata ttttggtact ctcctgctcc attgcttttt actaatcctt gacttaaagc
    18421 tggaaagtga aaggccgaat tgatttcatt gaaagtcatc caatatttga ctttactgct
    18481 gtatctctct aatactgtct gagcaaatcg ttcatagaag tcgatcagtt ttcgattttt
    18541 ccagccaccg tattcttttg ccaaatgaag aggcatttcg taatgagaaa tcgtgatcac
    18601 aggttcaata tcatatttta agcactcatc aatcagctga tcataaaatt ctaatcccgc
    18661 ttcgttagga gtaccttcgt ctccatttgg aaaaattcgt gtccaggcaa tcgaaaaacg
    18721 ataacatttg aatcccattt ccgcaaacaa ggcaagatct tctttgaaac gatcgtaatg
    18781 atcgattcct cgatgattcg ggtaaatata tttttcttga tcaatcgtcc agtcaaattc
    18841 ttcactgccg ataatcgcaa agcgctgctt acctccaggc atagcatctg caacggatag
    18901 tccttttccg tctcgatcat aagccccttc taattgattt ggcagcagtt gctccacccc
    18961 ataaaaattt ttctgaaaaa cgtgattgca tcctgatttc ctccttattt tacaattgcc
    19021 agaacatctt cgtttgcaat aatctctttt tggtctaatt caagtatatc ggcaaatgca
    19081 tcagtattcg taatgacaac tggagtgatt acgctatagc cagctgctct aattgcttcg
    19141 atgtcaaaac gaatcaataa atctcctgct ttgacgagat ccccttgttt gactaagatc
    19201 tcaaagccat tcccatttaa ttctactgta tccatcccga tatgaatcaa aatctccgct
    19261 ccgtcagtcg ttgtgatccc tacagcatgt ccagttggaa aaatagtcgt gatctctccg
    19321 tctgcaggtg caactagttc tcctacttct ggatcaatag cgataccttt tcccatcacg
    19381 ccagaagaaa aaacttggtc tggtacttca ctcaatggca gtactttacc cgttaaagga
    19441 ctttttaagg tatgccgtgc tgaagtaatc ggttctcctg cattcgcatg tttgttttct
    19501 aattgattgt cttgtgtttg ttcgtcaaat cctaaaatca atgtacctac gaatgcaaga
    19561 acaaaagcaa ttcctgtagc tattactgct actgtcacat ttgactctac accatccacc
    19621 gtattaatga aagtcggaat cgtcaataag ctgaccaaac tgctggagaa agcttttact
    19681 ccggaaaatc cgataatagc tccaccaata cctccagaaa tacaagcggc aatgaatggt
    19741 ttcttcaaag gtaatgtcac accatacaca gttggttcag tgattccaaa taacgaagtc
    19801 actgtagaag aaatccctaa tgctcgaagt ttcgtatctt ttgttcgcaa tgctacagct
    19861 aaagcagccc caccttgtgc caagatggct ggaagaagca ttggcatcaa tacatcaaac
    19921 ccatattgtt cgatattcaa aaacatgatc ggtacgaatc cccaatgcat gccgaacatc
    19981 acgaatactt gccataaact tcccatgatt agacctgcta cgattggact aaatccataa
    20041 atcgagttga agagaccgcc taaagcatta ccggcaaccg tcccgattgg tcctaaagca
    20101 agaaatgtta atggaaccat cactactaaa acgacaagcg gaactaaaat catttgcaga
    20161 aattgcggaa tcactttttt tacgaatggc tctaatttac tttgaaccca tacggctaga
    20221 atgattggta tgacagaaga agtataacca gatggtgaaa gaatcactgg gatcccaaag
    20281 aaactgatag cttctcccgc accagcaact gctgtgatag ctggatacac aagtgccata
    20341 gcaattgcta ctgctaaaaa ctggttggct ttgaactttt tagctgctgt aaaagcaagc
    20401 atgacaggta agaaggtaaa gacaccatct gctgcagcaa acaatatttg ataagtaccg
    20461 ctatcagctg tcagccagcc catcaccgtt gccaatgata agaatccttt caataccccg
    20521 gcggctgcca tcgcccctag aaaaggtgta aatatactag agataatatc gatcagacga
    20581 ttcaaaatat ttttggactc ttcttttcca tcctccgaaa ctgcaagacc ttcctcatcc
    20641 acgatcgatt gataaacatc tgctacatta ctgccaatca ctacttgata ctgaccgcca
    20701 ctttgtacga cttggatcac gtccgggtct tcttttaact tttgcgtatc tgctaaagat
    20761 tcatctttta atctgaatcg caaccgcgta gcacaatgta ctaaactttt gacattcttt
    20821 tgtcctccta ccgcttccca tacacgacga ccaactgctt gattatccat tgttttttcc
    20881 ttctttcttt tttatttaaa aaataaaaac ccagattgaa aaaaacagtc acaaacattc
    20941 gtgaacctat tttttcaatc caggttttgc ctgccataca gtaacaatcc ttatgattgg
    21001 atgctttttt tctcacttac tactctttga atatgaatcg ttaaataaat ctgctctgcg
    21061 atccccattt cctgtttttg cgtttgtcga agatactcat tgatccgttc gacacaatga
    21121 aacgcttttg gatactttcc ttgaactaat gcgtagagaa attcatcttg ctcgtcagat
    21181 ccttcccctt tgagataacg ctgggcaaaa aactgcagat gagtaatgat acgctgataa
    21241 ttcaaagatt cttcatcgaa cacgatgccg aagaatttac tgatgatact cagtatatct
    21301 cttaccattg tggtagcggt catcgtcact tgcatgtctt cgtttccttg ttggctattc
    21361 acaaaatgaa aggcaataaa accggcttca tcctcagaaa gttccacacc cgtcttttgt
    21421 ttcacgaaca aaagagcctc tttcgctgct tgatattctt tcggataaaa tttttttgtt
    21481 tcaaataata atggattagg cagttggata ttttcttttg ctcgtgtgat cgcataatga
    21541 agatgatcgg tcaatgtcag ataaatatta ggcgaaaatt caacttttag tttatcttca
    21601 gccagttcga ctacttgttt gacccattcg atctcctctg ccggaatatc agccatcagc
    21661 tgctggaatt ggtttttagc aaaagaatct cttaaaacaa attctttttg gaccgcttct
    21721 ggcgaaatct cgtccccaat ctttttttga aaagctagtc cttttcccat acaaacgact
    21781 tcttccccga atccattttt cgaaatgacg acattgttat tcaaaatttt atcaattttc
    21841 attttgcttc gccctctcaa gaaaaataaa aaaacctaga attcgcctac tgtttcttag
    21901 ctgaattctg gttttgcctg ccgtacagta acaatccatt tcttattcaa aatcatcata
    21961 ccatcgaatt tttatttatg caagcctttt catataaaaa ataaaaaaac tggaacacaa
    22021 gtctatctag aaaacaacca aatcagagat gcacctcttt gcgtttctct ttttttcagc
    22081 aaattggttt ttccttatcg attcatatcc tttggctgtt tttaatctgt aacgacttat
    22141 gtcccagtat cctaaaatgt ttttgtctct agattgaaag cagatctcat atcatctgtc
    22201 gcatctttta tcgatgtaac actttccagt tctccttgta caactagtcg cgtgacggcg
    22261 tccatgtcgc cacaagtaat tagtgtgaca atttcttttc cctcgacttc attcagtaat
    22321 tgggtatctg taggagcaac tttttcttta aaaaatgttt tgtatgtata cacattttct
    22381 aaatctgtca aatagatctt ggcacccatc tctaaatttt ctagcggtgt aaacagcaat
    22441 tcagggttcg ttgcacgatg gcttgctaag gcataatttc cttttcccat ttcttgatct
    22501 ggagataatg ttcctgctcc gtaaagtagt gacgtattat ccaagccttt gaaaaccggt
    22561 aaattgattg aaactgaagg gactgcgata ctagcaatca ctggtagatc tgttcctctc
    22621 atttgcgacc tcatgacccc ttctgtcgtc attggttcta ccgcatcaaa gtcaaaactg
    22681 acatctttat cgttattctt tttcagatct tcttttgtta cattcgctat agcatattta
    22741 tctcctgtct ctctgacaaa ataatccttg atctgttcat tgaaaatcaa agctagtcct
    22801 actaataaca agaggaacaa gaggatattg actagccatc tttttgcttt tccttttttt
    22861 ttcattttct ctccctccag actcatttta ctgtttttct tttgctcttt ccaacagccg
    22921 aatgacacat ttctacaact ctgtgtattt ttttcgtaca cctgcgcttt tttctacagg
    22981 atatttcaaa ttatttttga tcaatttttc ttcaatgatc tcatctagat ccaggtgaag
    23041 gttgtctgcc atcatgtatg aatagatcaa tacatctgcc agttcttctt tgattcgttc
    23101 taattgtgtt tcttttactt cttccggcgt tttccattga aaaagttcta acaattcaga
    23161 tgcttccaaa gaaatagaga tagccaaatc tttttcgtta tgaaattgtc gccaattacg
    23221 ttcatctcta aactggttga ctttttccat actattcatt tgcttgcctt cttccaatca
    23281 cttcttactt gattaatcat accatttttt tacataaaaa atagatgatg cttttaaaaa
    23341 aactcctgtt ttcttttatt taaaataaat gtcatagaaa atcaataatt taggtagcca
    23401 ccatgtgtat gcagtagcgt gtcttcttcc cttgaggctt tttgtttttc gatacgttct
    23461 tcttcccaaa cagacaacgc tactagaatc tctcttaatg attttccttc ttcggtgagc
    23521 gagtactcta ctttaggcgg gacttggtta taggcttttc gatggatact ttcatcttgt
    23581 tctaactctc ttaactgctg ggtcagcatt ttttttgtga tcgtagggat ttgcttgctt
    23641 ctccacgcct aaaataagcg atattgctct tccctttatc tggtgtaagc aaagcagtta
    23701 gcattttgac gatcgtgggt tccgcttttc acttcttatc tacttagtat catgaagtat
    23761 actttcgtac taatactaag tagcggaagt gtcaactact ttgtttaact acatagcaaa
    23821 agaaacagaa gggtgacaac ggtcatcacg cttctgtttc ttttgaatat gctgtgttgt
    23881 tgtctctatc tccgtgtaga ctttcctcaa acttatcctt tgacagtaag tcagtaggct
    23941 gatttgctct ttctagatgc cagatacatt tctacaaaaa aatagtgatt ctgttttgaa
    24001 aattcgattt ttagttctgc atttccgtaa acatccaaca tttttttcgc actgtataga
    24061 cctaacccgc catttttttt agaggttttt cctcttttga ccatctccga tagcgtcaaa
    24121 ttcgttggat ttgccttgtt cgctatacta aaacgtgatc cctctttttc ttccagtaga
    24181 ttgatcgtaa tcggactctg atcggctaca cgatgatcga atgcgttaga aataaaaata
    24241 gataaacagc gaataaaaac aaccagatca atcgggattg ttttcacttc gacaggaata
    24301 actacttgga tcgggatttt ctccgattct gctttttcta gaaattttaa aaagacaccc
    24361 ctgacagctg gggatacaat atttgttagc tgttgtattt gcggtttttc aaaaatagct
    24421 gcagaatgat cttctaatat ttctaaaaat tccaacgttt cttttttatt ttcctgaaga
    24481 gtaattttta atgaaaacag tagactttta taatcatgtt tgaattcctc tagatgatgg
    24541 taatattctt catttatttg atacagttga agcgattcct gatgttgtct ttcttttact
    24601 tggaaactga tcaacataat ggaaaaaaac aaagaaaaaa aactgatgac tatcgacaaa
    24661 agagatagaa gcagataatt agatgagcgg aagtgaacac ttcccaatac caagtaaatc
    24721 acgccccagc ttaataaaat acaaatacct ccaaaatagt gttcagttgg ataagtaaaa
    24781 agcaagttga gaaatctcgt ctgtttgtct atacttttta ctaatagata gaaaataaat
    24841 gcgataagta gtgcaaaaaa acttgctgtt ccaagatgtc tctttcctaa ataatccatc
    24901 agatcaaaaa ccagaaaaaa gctgagtcca gtgatagcaa aaaaaagatt actgatcaaa
    24961 cagctgataa acaggttttt cgtagtaaaa taaaaaagaa acatcaataa taagccaact
    25021 aggtaaggaa agctcacttt agggatagga agtaaaagtg tcaccaccat caaagctata
    25081 caaccaaagc tgttttttac tagcagttgt ttcgaaaaga ataaatagat acctaaatct
    25141 aaaatcaaag taaaggtcaa ataaagtgtc actgttgcga ccatcttatt cctccattgt
    25201 tttgtttcaa aatgtacaca tattttttta ataggagcct gcatatgaaa aagtatttta
    25261 tcatagaaga taaccagttt cacagcgaat ggatcatcag agaattggtc aatcatcata
    25321 tcgagaatat cgtgcagctc acttctatct ctcaaatcaa tcagttgatc cagttgggca
    25381 ctattgataa tcacgatgtt ttctttatcg atatcgactt gaagcaatca ctcacaggta
    25441 ttgatgtcgc cgaacaaata cgtaaaaaaa atgcacatag taatattgtt tttttcaccg
    25501 cttatacgaa ttttgcagta gagatcatca atcggaaaat ccttccgatt ggatatatca
    25561 gaaaagacag gaatttatct gaacaaattc gtcaagtgct agaacagatc aattggaaag
    25621 aacagcagat cgtaaatgtc gataaaatct ttattgatca aaaaggtgga agtctcgtcc
    25681 tgtatcctcg ggaaatttta tatattgaaa gtatcaaagg tttgaaaaac caagttatgg
    25741 tcaaaacaac tacagaagat aaattagtga atacttcttt aaaacaattg aagacagagt
    25801 tagaaaagta tgcttacttt ttacttttaa aatcttactg tatcaactta tcgcaattgc
    25861 agaaaattga ttctgctcat tatgtgttag aatttttcaa cggtgactcc ttactcgttg
    25921 gtcgaaagat ctttgaaaag acaaaggaac gtttccatga cttccaaaaa actgcttcga
    25981 gttgatgaat aagagctgag acgtaagcat agcagatttc agggagtggg ccttgaatcg
    26041 gctccactcc ctgaaatcgt tgatatgatt ttacgcttcc tcttctgtag gagcatctgt
    26101 taacgaccat gtgaatgttg aaacgtagtt gtctacagca taattggata caggaacaaa
    26161 taattccact gattgtctcc cttgttccac attctctcct aatgaataaa tccatgtgcc
    26221 aatcccttca tttgctcctg cagttactag atctactgcc tgatctgctg ggatttcgat
    26281 tccttcagcg ccagttccag aaacggtaga tggcattcca ctgctattag ttgcgctatt
    26341 tcgaatcacg gcgtttttga atttcacctt tgaaccagtt agtttattcg tatcagatgt
    26401 tgtaccaata aattctgttc gtttgactga taatttccaa ccggcataat ttccgctttt
    26461 atccgttact tgtacgaaat tctgtacttg tgtttgtgct ccagtactgt ccgttccgct
    26521 ttgtaatgca gcatatactg tttttgctgt acctaacttg attgttccaa aatcaagatc
    26581 tggagcttgg tcaatcgtca gtaatccgga tgttccctga tttggttcgt caggtgtaaa
    26641 aggagtatca ggatcatttg gatcaacagg aggaactgga acaacgtctt caggatttgc
    26701 agcatctggt ttggtcacag aaatcgttcc ttctgtagtg gctgagctct tattctcagc
    26761 aaaaacactt tgtgtacata ataatagact tccagctaga acggtactta atgcaattgt
    26821 ttttttcatt tctttttcct tctttctttt aaaataaata atccagcaaa taagccaata
    26881 agaatgactc caacaagtat cagccatcgc cagtcaaatg tttctggctg attttttaaa
    26941 tcaatatcct tttcattcaa ttggtccgct gcatcatcag ttatttcaaa atcggtatgg
    27001 agattccagc gtttttcttt ccaagcaccc ttcacaaccg cttgataatg tcccggagct
    27061 aatttttttc cttctaatgg gacaagtaaa tcaaaatttg tattgggtgc tacatctatt
    27121 ttttcttttt ttattgaaag gtaaggctct tttgtttctt ttttgtagat ttcaaccgat
    27181 gtagtcaagc cgaacatata agaagcattt ggattttgaa gattcgcctt aatcacattt
    27241 cttccatcgc tttgatccgc ataagctttt tttaatttca aatctgggga agactctttt
    27301 tcgctatttc aaatcaagat tgctttcact tgagaaaact gattgacgac accaactgta
    27361 cttttgttag aaacgttctc ttttttttct tgaaacgtga tccctcctgc gaccacacca
    27421 gccagctctt tttctggcgc tttcagtgaa agtgtctcag tgaccgcact ttgaggagga
    27481 acagttattt ctcccactgt ttttgctaag tttttcatat cataacttaa tgtttcatca
    27541 aatttacttt ttgattctcc atattcgatc acaccgtttg aattcgtcgt agcggagtgg
    27601 atcaatgtct caactgttac tgatttatct gttcggttaa agaccgtgta ggggatttcc
    27661 tgtgttttcc caggctccat ccttacattt atatatgttt tgttcttatc aatctgatta
    27721 gccggtaatt caaaatctac cgcaaaattg aattcggagg catggacagg tgtctgccaa
    27781 aggatgaatc caaggagaag gatcataagt aaagagcagt tgtttcgatg acttttattc
    27841 catattcgat tcatcaatca tcctccttga tctttattct gtcggcgcat ctgctaatgt
    27901 ccatgttatc tctgctgagt aattaccagc tatctgattt tctttggtta agacaagttt
    27961 aaacgcccga ccgttattta aatattctga ataatctgct tgcacattcg ttgaattttg
    28021 tcctctgaca atttccagtt cttcttcatt cactaattga tactcctctc ctttcttgaa
    28081 atataggaca tcctgcatag aaaatcctgc atcatttgtg aaaggctgag ataattttat
    28141 cgttaagatc cacggatttt tcgtttctcg ctgatcataa atccataatt tttcctgtat
    28201 atccatttgg ccaaatgctt cttgtgtcaa accagttgct ttgatctgac caaaatcgag
    28261 tttggaaggg gcaagaaatg agagaccacc ttctactacg atcttcgtag caggtgcaaa
    28321 aggcggggca tcatgataaa caactggcgt atcacttgga ttgtgattcc caatttcatc
    28381 gttggtactt ggcttgttct gcacaccctt agcagtagct tctcctgctt ggtcgtttaa
    28441 tacaatttct aatacatctc ctgcaaaaag ttgattttct gggatagaaa gaacaaattc
    28501 ccctgtatca tcaatagttg tttctgacaa aacagcttga ttttttttca atgaaaccaa
    28561 ggctcctgct tcacctgtac ctgtgatcgt gcgagaagct gcattgatca atgtggtact
    28621 taaattagca ggttcaggag gaatcacatc gactgtcgtt ttggcagagt ccagttctgt
    28681 cacttcttgg ccacctctta cttttttagc agcaacaact tgcacttgat cctccgtttt
    28741 taatctctca tcattgggta cttgaacttc gaacaagccg ccttgttcgc cttctcccca
    28801 tgggttatat cctgcccctt cattttcatc tgtttgtcct tgcgtgagag cagtaatttc
    28861 tacagatgat ttcgtcgtat ctgcgtaagt aatacgtaaa gtcacttcta cttcgcctgt
    28921 ccaagcatct cttggctttg cctcgacacc ttcgggaaca tcgacatgcc catagatttt
    28981 tttatctgca ttcgttggca ctcttaagga ttcaatcatc gggagctgat tattggcact
    29041 gattcgatta taatttttca ttccggcacc tgtctgagca aattcatttg ttaaacctgc
    29101 actagggctt gatacgaaat tgcctaagtc ggtcccattg atcgataagt ctgtcatatc
    29161 agaaaaataa tccgggtctt tttcaaagtt atcgaatgtt gcgcctgttt ttcgccataa
    29221 agcgatttct gaatgggcga tctttaaaga agaatctcca tttccttgga atacccagcc
    29281 gcctatgcca ttggtctcgc ttccaatccg tttgttttgg aaatcaaaat aggtaggaga
    29341 ttctaagtcc acattcaaca catccccact gatgatgccg gtcttatctt cccctgtttt
    29401 cccgaccatg actaaataag ttttttcacc tgccgtaaaa tttaaatcaa tatctccagt
    29461 tgtatctaca gttgctccgg aatctgcgcg tatatcgata tttgattttt ctccagtgac
    29521 tgtaaaatca gctgaacctg gactttctag aaaaccagaa gcgtcataaa attggatcgc
    29581 ttgatttcct tgattgagtc tgttcacgta agatttgcca tcacctgtat ttcttaccct
    29641 caatgagcct ccattggtta ctgtcagctt ttgcgtacca ttctcaaaac gaactgcgct
    29701 ggaacgccca ctctgcttat cgatgtcgat aactgatccg gctccttcta cgatcaaaga
    29761 aaggcctttt cctacaaaac gcatcccatt gttcccgggt tgatcgtcat ctccagccat
    29821 tttgaccgag atttgtccac cacttgatac atggatttga ctagaatctc cttgcaagcg
    29881 aaatccgccc gtagttgctg tattgatggt gattttccca ccattcgata cagtgacttt
    29941 cgatcctgaa cctctcattt ggatgattcc gcgattgttg tcattggtaa tattgatctt
    30001 tgtatttacc gaaaattcgc ttcccgaacc actgacttca aacatgacat taccaggtag
    30061 cgtatcgact gcctctcctt catcgctaac gccatctgcc cgatcataat caagagagac
    30121 ctttgaaccg cttaagatat ggattcctgg cgctgttttt ccactaccag tctcatctcc
    30181 tgaatctaga aaaccgtaga atttccctag atacggtcca taaagttgac taccattgat
    30241 cacattcaat tgatagcttc tacaaaaata ggctttaccc ggagcggcat tcagtccttc
    30301 cttcactggt tggacatcca acacaccgga aacaccatct aatgtgacag ttgcacgagg
    30361 agcgtaaatc agtcctaatt tggacccatc atacaaatca agtgtcccgg taaattttat
    30421 ttctcccgta aaatgatatc tgcttcccca aaaatcggtc atataagcaa tgataatggc
    30481 atttccatcg atatttggtg tcaatccacc tggatgtgca gctgttcctt taaaattctg
    30541 gaactcgatc gactgaggta tctcattgat ataaatatgg tgtgtgccga aattgtgagc
    30601 gaatccacca aaatcaataa cgatatctcg tttgatctct aattccctgt ctaaagtcaa
    30661 aggctgaatc agtcggatct tagttactga ttcgtctgcg agaagctgcg ccagttcttc
    30721 tgttgtggca gcttcgctgt acccatccgc tgaaacagct cttgccagtg ccgcttcact
    30781 gctatcagac gtttgttcag ctacttctga ggtctcactt gtcttatttt cttcttgcct
    30841 tttattagta gaagcctcac tttgagattc tgtagtttca gaagtaatcg attcttctga
    30901 aaaagtagtc ttgtcaaaac tttgattctc tgattgcgtt gattcgtttg ttttctctac
    30961 atcggcaaaa acggatgtca ccatcaagag agggaagaca aacaaaatcg acgcaatcag
    31021 cttttttaca cattgattca ttctccacca tcctctctga cgttttgaca attttatttt
    31081 atcgttttaa tctatttcca attgtacttt catatttaaa atatgtattt ttatggaaaa
    31141 atttttctat taggtgtaaa tttctttttt gtacaaaaaa aaggctgtga caaaagtctt
    31201 gtcacagtcc cttatcccga acaagcggtg ttctcccgcc aactcctcgg tcacaacctc
    31261 cattttaaca ataaacctgt aaatgtgagg gcaatacttt gattgtcaca ggtaatttat
    31321 ccccttcatc tccatcaaca ttcgtcgtca attcttcctc atcagctaat gacacaacta
    31381 attgctcaca agtaaggtag gctagatttt tcgtagattc atctactcct tttaataggt
    31441 ctggcaatgt tttaagcgta tcgatcaaag aagaatcttt taaataaacc aaatggagct
    31501 taccatcatc cacttttgca tttggaagta atgtttcaaa accgccgact gagttagtta
    31561 gtcctatcag caaggtactg ctctcaattt cttccttctt tccatcaact tctacgtgaa
    31621 acgagtagga ttgtgtggaa gctaactgtt tgattcctga catgaaataa gctagttttc
    31681 caaatttcgt cttcttctcc gcatctacat cattgattga ttcagggata gagccaattg
    31741 cgacgacatt cataaaatag tcgtcattta tttttccaat atccaatggc ttgactgatt
    31801 caatcgaaaa atgattgatc gcttcctcag gttctagcgg tatccctaat gctcgagcca
    31861 agtcattcac cgtacccaat gggaaaaatc cgaaatttgg ccgatgttct tgttcagcga
    31921 ttccactgat tccttcgttg actgttccat ctccgcccat gacaaacaca ctatgatacc
    31981 cttccgtagc cgcttcgcga gtaaagtttt ttgcatcccc tgcttttttt gtatgcaaga
    32041 cgaccacttc atcaaacacc gattccaatt ttgctatcgc taattgctca aattcctttg
    32101 cttgttcacc gcctgaactg gggtttacca ctaataaaac ttttttcatc actttctttc
    32161 ccttctgatt gatttcttta atataacgat agcataaaga aaaaaattag gctgtgatga
    32221 agtactgttc atgaaacatt catttatttt ttgacaagat aaaacatcca tactatgaaa
    32281 ctgaggaaaa ttaaaacaat gatataggaa ataaaagaaa atgataggca ttgtatacct
    32341 aataaagtaa aaatcttagg tggcagataa aaacacaaaa atagcaagag aatgtaatag
    32401 cgtttcttcc actttttgtt atcagacctt atagcgatca gaggaatacc aaatgcataa
    32461 ctgaaaaact cttgatgtac tgttaatatg tcacggcctt gaataataaa tgcgacaatc
    32521 cccgctataa ttagtgtgcc taacaccaaa acggaaaatt gatgaatata ttttatatac
    32581 aaatgatcca ttgtacttcc tgccttttta tttgtgagaa aaacaaatcc gtatacgtga
    32641 ataacttcta gaaataaaag aaatttgcaa aaccactcca tttatctact tctacgtgca
    32701 ttttttgata ttgttttctt tatttaagat tatacagaaa aatatctagg gtcgctggat
    32761 tctaagtaaa aaaaattttt aaaataaaaa gaactaaatc aagtagtaat taaactactg
    32821 ttgatttagt tctaataaaa agatttagat gaacagtttt attgatttaa atagttcata
    32881 ttttttattt ataccgctta tttactactt gctgtactag aatctgaagt gaatgtactc
    32941 aaaacatttt caaagtcttt gtctttgatt tttacattag cgtctttcaa tacttcgcca
    33001 attactttat tctggaaggt actgtcactt aattttgtgt ctgttgcaat ttctttcaat
    33061 tcttttttgt atttatccat gtcgttgcct ttgttttggt ttttcaccat tttaaccaca
    33121 taatattccg tagtataagt tgaagcattg gtagaagtga tcacatcaga aacttgacca
    33181 tctttcaact taaaggctgc ttctttgact tctgccggaa ccgttgtagt agtggaatca
    33241 aatttcactt ttccgccatc ttcttttgtc gtagtatcag ttgacttgtc tttggctaat
    33301 ttagagaaat cgtctccctt atcagcagct ttcttcacat cttttgcatc atcttcactt
    33361 gctacttgga taatttgagc ttccacttct ggatggaaag attcccaagc cgtttttaaa
    33421 tcttcatcgg tcaatttgat atgtttcttt agaccttctt gaaaggctag actttgtttg
    33481 atactgtctt tgaatgtttg ttctgtgtaa cctgcagatt tcaattgtga atcaaatgaa
    33541 tcacccaatt gtttctttgt ttgatcatat tgagaatcga tttctttggt tgatacgtca
    33601 tctccatatt tatcttcaaa tacttgataa acgatcaact gttgcacagc ggaatctgct
    33661 ccttgcattt ttttcaagct atccattact tcttgttcgc tgattgtacc gcctttataa
    33721 ctaacggctg ttttttcacc ggcattcgta cagcctgaca ataagccagt gcctagtacg
    33781 atggcaagtg ctaaaaatct ttttttcatt tatcaattct cctacttttc gttttttgcg
    33841 aattgctaaa aacaaaggtg ttcaagatga aaatcatcaa gaacaccttt actaatctgc
    33901 tcgatacgtc ctgaatagat ataaggctac acaatccaga aagttcgctc agcagaataa
    33961 atgtcaagta gcacatcaca ccttaatata ctacttcttt tgttaccgtt tttcaagtct
    34021 atcttgcgtt ccgtatttaa cgtaactaat tcttagaaca aatgttatcg attttgtttt
    34081 tcttcttccg ctgctgggat attcaaatca gacactttta tgttcgattt tccagacatt
    34141 tttttgttgt ttttattatg atatattttt atacaactaa aaatgaatat attaaaacta
    34201 ccaaaaataa
//
LOCUS       DAXQKX010000027        32533 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.027, whole genome shotgun sequence.
ACCESSION   DAXQKX010000027 DAXQKX010000000
VERSION     DAXQKX010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32533
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.027"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            131..505
                     /locus_tag="ACF3MF_001421"
     CDS             131..505
                     /locus_tag="ACF3MF_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFE3927421.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="ACF3MF_001422"
     CDS             complement(619..1248)
                     /locus_tag="ACF3MF_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFE3927422.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="ACF3MF_001423"
     tRNA            complement(1382..1454)
                     /locus_tag="ACF3MF_001423"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
     gene            1668..1741
                     /locus_tag="ACF3MF_001424"
     tRNA            1668..1741
                     /locus_tag="ACF3MF_001424"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1702..1704,aa:Asn,seq:gtt)
     gene            complement(1879..2043)
                     /locus_tag="ACF3MF_001425"
     CDS             complement(1879..2043)
                     /locus_tag="ACF3MF_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927423.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2338..3666
                     /locus_tag="ACF3MF_001426"
     CDS             2338..3666
                     /locus_tag="ACF3MF_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HFE3927424.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3868..4701
                     /locus_tag="ACF3MF_001427"
     CDS             3868..4701
                     /locus_tag="ACF3MF_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HFE3927425.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4717..5454
                     /locus_tag="ACF3MF_001428"
     CDS             4717..5454
                     /locus_tag="ACF3MF_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HFE3927426.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5609..6577)
                     /locus_tag="ACF3MF_001429"
     CDS             complement(5609..6577)
                     /locus_tag="ACF3MF_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HFE3927427.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6809..7642
                     /locus_tag="ACF3MF_001430"
     CDS             6809..7642
                     /locus_tag="ACF3MF_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HFE3927428.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7676..8515
                     /locus_tag="ACF3MF_001431"
     CDS             7676..8515
                     /locus_tag="ACF3MF_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFE3927429.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8541..9101
                     /locus_tag="ACF3MF_001432"
     CDS             8541..9101
                     /locus_tag="ACF3MF_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFE3927430.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9300..11021
                     /locus_tag="ACF3MF_001433"
     CDS             9300..11021
                     /locus_tag="ACF3MF_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HFE3927431.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11186..12328
                     /locus_tag="ACF3MF_001434"
     CDS             11186..12328
                     /locus_tag="ACF3MF_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFE3927432.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12344..13555
                     /gene="thiI"
                     /locus_tag="ACF3MF_001435"
     CDS             12344..13555
                     /gene="thiI"
                     /locus_tag="ACF3MF_001435"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HFE3927433.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14128..14775
                     /locus_tag="ACF3MF_001436"
     CDS             14128..14775
                     /locus_tag="ACF3MF_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HFE3927434.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    14904..15120
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15168..17813
                     /locus_tag="ACF3MF_001437"
     CDS             15168..17813
                     /locus_tag="ACF3MF_001437"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HFE3927435.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18123..19436
                     /locus_tag="ACF3MF_001438"
     CDS             18123..19436
                     /locus_tag="ACF3MF_001438"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HFE3927436.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19426..20079
                     /locus_tag="ACF3MF_001439"
     CDS             19426..20079
                     /locus_tag="ACF3MF_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFE3927437.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20134..20826
                     /gene="radC"
                     /locus_tag="ACF3MF_001440"
     CDS             20134..20826
                     /gene="radC"
                     /locus_tag="ACF3MF_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HFE3927438.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            20976..21176
                     /locus_tag="ACF3MF_001441"
     CDS             20976..21176
                     /locus_tag="ACF3MF_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFE3927439.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(21430..23109)
                     /locus_tag="ACF3MF_001442"
     CDS             complement(21430..23109)
                     /locus_tag="ACF3MF_001442"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HFE3927440.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(23111..23323)
                     /locus_tag="ACF3MF_001443"
     CDS             complement(23111..23323)
                     /locus_tag="ACF3MF_001443"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit epsilon"
                     /protein_id="HFE3927441.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            23716..25446
                     /gene="efrA"
                     /locus_tag="ACF3MF_001444"
     CDS             23716..25446
                     /gene="efrA"
                     /locus_tag="ACF3MF_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HFE3927442.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            25443..27203
                     /gene="efrB"
                     /locus_tag="ACF3MF_001445"
     CDS             25443..27203
                     /gene="efrB"
                     /locus_tag="ACF3MF_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HFE3927443.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            27298..27495
                     /locus_tag="ACF3MF_001446"
     CDS             27298..27495
                     /locus_tag="ACF3MF_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927444.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            27648..28133
                     /locus_tag="ACF3MF_001447"
     CDS             27648..28133
                     /locus_tag="ACF3MF_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HFE3927445.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(28237..28830)
                     /gene="clpP"
                     /locus_tag="ACF3MF_001448"
     CDS             complement(28237..28830)
                     /gene="clpP"
                     /locus_tag="ACF3MF_001448"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HFE3927446.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            29010..29537
                     /locus_tag="ACF3MF_001449"
     CDS             29010..29537
                     /locus_tag="ACF3MF_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927447.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            29628..30365
                     /locus_tag="ACF3MF_001450"
     CDS             29628..30365
                     /locus_tag="ACF3MF_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HFE3927448.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            30369..31286
                     /gene="miaA"
                     /locus_tag="ACF3MF_001451"
     CDS             30369..31286
                     /gene="miaA"
                     /locus_tag="ACF3MF_001451"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HFE3927449.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            31288..32517
                     /gene="hflX"
                     /locus_tag="ACF3MF_001452"
     CDS             31288..32517
                     /gene="hflX"
                     /locus_tag="ACF3MF_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HFE3927450.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTREGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT        10771 a         5522 c         6875 g         9365 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt acttgattcc ggcatagctc
     1681 agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc tactgccgga
     1741 gtaaataaag cttatgcaaa gaaaaagaaa tccaatcact tgggtttctt tttcttttat
     1801 tattatgatg aatcaagctt tctgtttttg tcacgtatgt tgtaatcttt acgaaagagt
     1861 agagttggct actcataatc aaccatactt cccatcatcg ctaaatacga aataaatcag
     1921 cattcctaca ccaatcaaag cacaagctgc accaagaaaa gggatgacat tcccaaagtt
     1981 atctgtattc ataagtatgc caccacccac aaacaaaaag ccgccagcaa tcaggttttt
     2041 cattttattc atctcctttc ttacgttata gtatttcctt ctttcaatga gtattttgaa
     2101 agctatctta ttgtatgatg ttcttctagg cctcttcttt attatacagg ccattttcgt
     2161 tatctcatag aaatattcct ttttatctga aaactattgt ataccgtatg acatttttct
     2221 tcatgaagtt gtaagtatat tctcattcaa atgaaaattt catcatagaa gagattgtat
     2281 ttctaaattc ttaagagtaa aatacgaagt ataacttgga tttggaagga tgattggatg
     2341 aaagctatta cgcctgatat gacaacaaaa tttaacaaac agtttcaagc aaatatcaaa
     2401 cagcaggcat tgcagcgggc agttgtgaag aacggaatta ctgcttctgc tgaaaatgtt
     2461 tcagcacatg tggagaatac accggtattt tctatagatt tggctacggg gaaagtggct
     2521 aatcaaatgc aatcggggcg ttgctggatg tttgctgcac tgaacacatt ccgtcataag
     2581 atgctgaatc aattccattt aaaagagttt gaattatcac aaaattacac ttttttctgg
     2641 gataaatatg aaaaggcaaa ttatttctat gaaaacatca ttgcaacagg aaaagaggca
     2701 atcgatagcc ggaaagtagc tttcttactc gctactcctc aacaagatgg cggccaatgg
     2761 gatatgatcg tttcattatt ccaaaaatat ggcgttgtgc ctaaatcggt gatgccggaa
     2821 agtgcgaata gttcaaattc tcgagatttg aataactact tgaacaaatt actgcgtaaa
     2881 gatgcagtag tgttacggaa aatggttgct caaggagaaa cattagacgc tattgaagaa
     2941 aagaaagaag aaatgctaga aagcatttat aacttcttag ctatctcatt aggaacacct
     3001 ccaaaagaat tcgattttga gtaccgcgat gaagaaaaga actatcatct tgaccgagga
     3061 ctgacaccac aaatttttta tgataaatac atcggtgtaa aattagatga ttatgttagc
     3121 gtgatcaatg caccaacaaa agacaaacca ttcaatcgtt cttatacagt agagatgcta
     3181 ggaaatgtcg ttggcgggaa agaagtcaaa tatctgaatg ttgatatgga aactttcaaa
     3241 aaattagcga ttgctcagct tgaagaagga gaatctgttt ggtttggttg tgatgtaggt
     3301 caatcttcta ctagaactag tggcatcatg gccttagatg cttattcaat ggatgatcta
     3361 tttgatacgg attttacaat gactaaagct gaacgtttag attttggaga aagtctgatg
     3421 acccatgcga tggtattgac cggtgttgac ttagtagacg ggcaatcaac aaaatggaaa
     3481 gtcgaaaata gctggggcga aaaagttgga aagaatggct tctttgttat gagtgatgcc
     3541 tggatggacg aatatacgta ccaaatcgtt gtaagaaaag atttattgac gaaagagcaa
     3601 ttaaatgcgt tcaatgaaga accaattgtt ctatctccgt gggatccaat gggtgcttta
     3661 gcatagacga gtatttcaat gaagagtatg tagtaaagat aaaaagagct ggcttaagcc
     3721 agctcttttt atctttaaag tccattccct gttttttatg gtccctgtgc tataattcta
     3781 aataaaggat aaggattgga aataatcctt ttatcattaa aaatatgatg acgaagtaga
     3841 ataaaattgg gagtaggggg gaaagtcatg gatatccaaa ctgttttatc tgatctgaaa
     3901 ttaaatggta aagtgattcc agttgttggt ggcgatgtta atcagaccta tcgtataaaa
     3961 accgaacatc gtgcttattt tttaaaaatc catccgaatg taaaaaaagg attttttgaa
     4021 gcagaagtag acggattaaa agaactgtca gcattcgtac gtgtaccgga tacgtatatg
     4081 ctaggtgaaa caagtgaagg cgcttatttg ttaatggaat ggatcgagcc gggaaaaggg
     4141 gatcaacgag atcttgctgc agctttagct aatctccatc agcaaacagc gccacaattt
     4201 ggttttcgta aagataacta tttgggtaca cttgttcaga aaaattcttt tgaagaagat
     4261 tggtggactt ttttctttaa agatcggctt gaatcccaga tttctttggc agaagaaacg
     4321 aatcgatgga atgtacagcg tcaagaaaag tatctgcgat ttaaagaacg tgtattgaaa
     4381 tcggttgaac caaaaaagat cactccacgc ctcttgcacg gagacctgtg gagtggtaat
     4441 gtgttctttg accagcaagg gcatccagtt tttgtcgacc cagctgtttc ttatgggaat
     4501 cgggaacaag atattgcaat gagccagtta ttcggtggtt tccgaccgga atttttagat
     4561 gcttatcaaa ctatatttcc attagaaaag ggatggaaag accgactgcc gatttaccag
     4621 ttatattatc ttttggcaca tttgaatatg tttggagaaa gttacggttc ccaagtagat
     4681 caattactag aaaattttta agaggagggc gtgtttttgg caaaaaaata taccaaaaag
     4741 catgaagttt catattatga gtgtgacatc aaccaaacga tgacatttcc ttcgatgtta
     4801 ggagtagtta tcaaaacgtc tgaagatcaa agcgaccagt tgggaagagg cagtgaattc
     4861 gtcaatagct ttggacttac ttgggtcatc acgaattatt ccatggagat taatcgtctc
     4921 cctagagtcg gtgaagtaat ctcagtaacg actcaagcca tggagtacaa taagtttttc
     4981 tgttatcgga acttctggat ccatgatgaa gatgggaaag aattagtcaa aatagaatct
     5041 gttttcgtat tgatggattt tgtgaatcga aaaatgagca gtgttaatga agagatcatt
     5101 gctccttttg agagtgagaa gatcaagaaa atcaagcgtc aggaaaaaat tgaaaagatt
     5161 gattcgggct tcatgttgcc atatcgtgtt cgtttttatg atatcgatag taatcagcat
     5221 gttaataatg cgatgtattt taattggatc attgacgtat taggatatga ctttttgact
     5281 acgcatgttc cagaaaaagt aattattcga tttgataaag aagtagagta cgggaatgag
     5341 atcgaaagcc attttgaaca aatccctatc gaaaatggtg tcaaaacaaa acatgaaatc
     5401 cgaatgcaag aacagctgta ttgtgaagca aatattatat ggaaaaataa ataaaaaaga
     5461 ggttgtgaca gaagggggca acttcaagaa ataagaagaa atttacgaaa attgtttctc
     5521 aaatttttgt aaattttcga cttagttttc gaagaagcta tttttgtcac agcctctctt
     5581 tttaagttta gctattagat aatgatgttt agttttggat aaacgaaatc aattcttcac
     5641 ccgacaaacc atagtttaca gcaatcaata gttttaaacg tgctttttga ctattaatac
     5701 tgttacagaa aataatcccc attttttcta gttcttttcc cccgccttca taatcataaa
     5761 caggctctgc gattccattg aaacaacgag aaacaagtac tacagggatt ttttggacaa
     5821 gaagcttttc caaagcagct aaggcttgtg gagggagatt ccccgcacct aaagcttcga
     5881 ttaccaaacc gtctactttc gtatgggcga tggcttccaa taagtcccct tgcatcccag
     5941 catatgcttt aacgatcggg atagtcccat ctacagcgga aatgtccagt cgctttgttt
     6001 ctaaaagttc ctgcaagaat aaaattcgat tcttagttac taagccgatg ggacccaatg
     6061 taggtgttcg gaaagtagca acatttgtgg tatgggtctt tgtcacgtag cgtgcagaat
     6121 ggatctcatc gttcatgacc accaaaaccc ccttatctag cgcttcttca caacttgcga
     6181 cacgaatcgc actttcaaaa ttataaaggc cgtcacttcc aagttcatta cttgaacgca
     6241 ttgccccagt caaaacaatt ggtaatttgt tgccaatcgt tgtatcaaga aaaaaagcag
     6301 tttcttctaa tgtatctgta ccgtgtgtga tcaccactcc ggatatacct gatgcataag
     6361 cggacaagat acgttctttt aataccaaca tgtgagaagg catgatgtgt ggtgagggaa
     6421 gattgaagat atcttcaact aataattcta catgcttggg gattgtgatt tctgcatcta
     6481 ataatgggtt tgccacatca ggactaacac cgcccgtgag catgttttct ttcatggcga
     6541 tcgttccgcc ggtgtgtagt acaagtattt ttttcatttt acagacttcc ttacgaataa
     6601 ttttgcatag ccgttaaatc ttattgtata ctatataaaa gagttttgct atcagtgaag
     6661 aataacgaat agcctaactt atcataaaaa agctgacctt attaaaatgg aaaagactca
     6721 accttgacct cctaatacaa tggagtatct ggttgagttt cttttacaag aaagcagcca
     6781 aggaaatcaa tcacgaaggt ggccggaaat gatcagaatc ggattaacat cgtttaaaga
     6841 acatgacaaa ttaactggta aaaagaataa cactctttat gaatatgcag ggtttctacc
     6901 cttagtggaa ttagatactg cctattatgg aattccccga aagtcctcag ttgagaattg
     6961 gataagtgaa gtacctgaat catttcgctt tgtagtcaaa gtctatcaag gaatcagcgg
     7021 tcaaggagac tggaagcctt attatcagac cgaagaagag atgattgcgc attttttaga
     7081 tgttatgtcg ccaatggtag atgctggaaa gatgttttgc tttttagtcc aattcccctc
     7141 atcattcaaa tgtacgaaag aaaatgtcca gtacttgcgc aaacttagaa agtggtttga
     7201 gggttatcct gtttctatag aattgcggga ttattcttgg tacagcgatg aatttcttga
     7261 acgtacaaga aactttatgt ctagagccgc tttttcttta gccatcatcg atgagccaca
     7321 gttgctgaat acaacgattc cttttgatcc atttgtcacc aatccgaact ttgctctttt
     7381 tcgattccat ggtaggaatg cgcaaggatg gcaagcaaat gataaagagt ggcgtaaaaa
     7441 aagaacgtta tatcgttatt cagaaaaaga actgcaagaa ctagcacatg aagtcaaagt
     7501 agttgattct aagacaaaag aggtaggtgt gatttttaat aataattctg gtggtgatgc
     7561 ggctgaaaat gcattagcac tgcaaaaaat attaaatatc aagccagatg gactcaatcc
     7621 aacccaaatg gatctgtttt aagggcttat tttattcaag aaaggggcga agtctatgat
     7681 caaagctatt ttttttgata ttgacggaac attggtcacc aatcgttcaa aagcgttgga
     7741 atcaacaaaa caagcaattg aatatgctcg gaaaaacggc attttatgcg gtgtagcaac
     7801 ggggcgcagc ccagtaaaga tcaaagaaat cattgatgaa ttggaattag atatgtatgt
     7861 cgtgtataat ggtcaactgg tttttactgc agatcgcacg attatcgacc acccttttga
     7921 acaaaaagta ttggaacata ttgttgaatt tgcagatgag aaccatcgac aaatcgtttt
     7981 tggtgcgaga aatcggttag atggatcaac gacgatgcta ttaggacaat cgatttttat
     8041 caagcgacta gtcagctttt taccgcgtaa attcccggta cgtctgatga aaaaaatcct
     8101 ccaggttttt agccctcacc gacaaaagga tcgttatgaa acgttagaga tattaaaaga
     8161 accaatttat caatgtatat tgctcagtcc ggagtcagaa cagaaaaagt tagaacatcg
     8221 ctttcccgag tgtacgtttc agcgttcaaa tacgtatact gtagatatca tcccaaaagg
     8281 tggttcaaaa ttactaggca tccaagcttt cgcaaatgct gtcgaaattg aaatggaaga
     8341 aattatggca ttcggcgatc attacaatga tatcgagatg ctgaaaggtg taggaattgg
     8401 agtggccatg gggaatgctc agatcgaagt aaaacatgct gcagactttg tgactcaatc
     8461 aaatgaagaa gatgggatat acgaaggact gaaacacttc ggtctgattt attagtcaat
     8521 gaaagaagga aaaaatcagt atggaagcag agacaccttt tcaaaaagta gaaacattcc
     8581 acaaaacttt tgatccaaga agaccagaga tacccacggc ttttacagaa aatgaagctc
     8641 atacacgtgc tgcgttcaaa atagaagaac ttgttgaatt tgttgcagct acttcaccta
     8701 ataaagaaca actgcatgaa gctgttatgc tgctgcacga agcattagat aaagcagaag
     8761 aaaaaatact tggtaaaaca cagtggggaa gtgatccgct ggttgaacaa gtagatgcac
     8821 tgacagatat cctttacttt acttatggtt ctttttcatt actaggaata gtgcctgatc
     8881 gaatattcga aatcgtccat caggcaaata tggggaaatt atttccagat ggaaaacctc
     8941 attatgaccc tgtaacaaat aaagtgttga aacctgaaaa ctggcagatg gaatatgctc
     9001 cagaacctaa aatcgcggca gaaatccaac gtcagattca agaagcgatt gctaagaaga
     9061 aatccgctga tataggcatg tgcacaaatg aaaaagagtg atcagagttt cactattttt
     9121 gttatcttta tacgatggaa aaacaaaaga ttttcgttta agttagtgaa tgcatgaaaa
     9181 tagtatgcta taatctagaa tagatgtctt ttgcacgaga gacgtattat ttggatttat
     9241 gccaagcaga acgccatctg ttgcataaaa gatgcatact gaaaacggag gaaccataaa
     9301 tgggaaataa tgttatcatc ggaatcgtca ttgcaatcat tatagtcgcc attgtcgtct
     9361 ttttggttag ttacttgatg aagaaaaaaa accaagatcg attggatgcc ttagaaaaac
     9421 gcaaggaaga attatttgac ttgccagtga ttgaagaagt cgatgatgtt aaaaaaatgc
     9481 atctggttgg gcaaagccaa aatacctttc gtgaatggag tcaaaaatgg aatgacatat
     9541 ctacttcctc gttcgctgaa ctagaaagtc aaattttcga agtggaaaac ctcaatgaaa
     9601 gttttcggtt cttaaaagga aaaaaagcag ttgttgaagc agaagctaca atggaccaaa
     9661 tggagaaaca agtgacggaa atccgtgaag gtctaaagga attgcgggaa acggaagaac
     9721 gcaactcact agctgttcag caggcacttg acgtctatga agaactgaaa gaaaaagtca
     9781 gagaagacga gcatgaatac ggaccagctc tttttgaatt gcaaaaacag atcaaagtga
     9841 tcgaaaaaga atttacgcag tttgtgactt taaacacttc tggagaccct gttgaagccc
     9901 gcgaggtttt ggataaagca gaaaaacata cgtatgaagt ggaagctctg atgaaaaaaa
     9961 ttccaccgct gtatgaggag ctccatacca ctttccctga acaacttgaa gaaatcagtg
    10021 atacttacga gaaattgatg gaagaacaat atgtattccc agaagaagat cttgctgaag
    10081 atatcgcaaa agtaagtcga agaattgaaa attcattagc caatcttgaa aaaacagaag
    10141 ttgaaacggt cgaatttgaa aaccgtgaaa cagctgattt gattgattcg ttatatgata
    10201 tcttagaacg ggaaatggaa gctcagagat atgtaaaaac taaccaatca acgattgcag
    10261 agtatatcaa acatacaaca aagaataacc gtcaattatt gattgagctg gatcacacat
    10321 ctcaaagcta tacattgaac cacaatgaaa ttggccgtgt acgaggtttc caaaccgaag
    10381 tggaagaaat ggaacgtcaa aatgaacaga tgattccaca gatccgtcaa cacgaaattc
    10441 cttattcaga agtgcgcacg ttctataaaa cagtcttcaa agtcttagaa gatatcgaaa
    10501 agcaacaagt agagatcgac gactcattac atgaattgag aaaaggcgaa aaagaagcgc
    10561 aagaaaagat cgatacattc gaattcaaat tgcgcagttt gaaacgtttt gtagaaaaac
    10621 aacgtttgcc tggcttgccg aatgattacc tagaattctt ttttgttgct actgaccgta
    10681 ttgaagaact aagtgttgtc ttgaataaaa ttcgagtaaa catggaagag gtcaatcgtt
    10741 tagttgctct atgtgaagaa gatctagaat tattagataa gaagacacat gatttagtag
    10801 atgcagcagc attaacggag caaatgctcc aatatgcaaa tcgttatcgt catacacacg
    10861 aagaagtgag agaagcaatt gataaaagct actatttatt caataaagaa tatcactatc
    10921 aagaagcatt agacgaaatc ggtacagcat tagagcgagt agaacctggt gctttcaaac
    10981 gcatcgaaga tttttatttt aatcatccag acttagtata aagcaaaaaa gttagtaaac
    11041 cagcaagagc aagacggatt attgtcttgt tcttgtcttt ttttgtatat ttgaaaattg
    11101 aaacaagtga aaatttcacc tgctcttgaa agcaccttgg acaaccgtta taatagaaaa
    11161 gaatttcaaa aaagaggggt ttcttatgat atattttgat aacagtgcaa caaccccaat
    11221 ctttccgcaa agcttagatg catatgtaaa aaccagtcag cggattattg ggaatccatc
    11281 aagcttgcat gatttaggca atcaagctaa ccggttgttg cagcaagcaa gaaagcagat
    11341 cgctgatttg atccatgtag aaccagaaga aatctatttt acttcaggcg gaacagaagg
    11401 agataactgg gtattaaaag gaacgatgat cgaaaaaaga gaatatggga atcatatgat
    11461 catttcagga gtcgaacatc cggccgtcag cgagacagca gaacaattaa aagaattagg
    11521 aatcgaagta agtatcgccc cagtggataa acgcggattt gtacgtgtcg acgaattgaa
    11581 agaattaata agaaaagaga cagtattagt ctctgttatg gctgtgaata atgaagtagg
    11641 atcgattcag cccatccagg aaatcagtga tcttttggat gattttccta aaattcattt
    11701 ccatgtagat gctgttcagg cgattggaaa agtaccattc tcgcaatggt tgacagaaag
    11761 agttgatttt gcaacatttt cagctcataa attccatggc ccacggggaa ctggtttcat
    11821 ttattggaaa aagggtcgtc gtttagcacc attactgaca ggtggagggc aagaaagaaa
    11881 tcagcgaagt gggacagaaa atgttccagg tattgtggct atggttaaag ctttacgttt
    11941 atcattagag ataaaggaac aaaaacctga gcagacacaa cgcttaaaag tagctctaat
    12001 caatgcgttg aagacgtatg agaaagtgac gattttttca gaaggaactg actatgcacc
    12061 gcatatttta tgttttgctc taaaaggaat tcgcggcgaa gttctcgtcc atgccttaga
    12121 agaaaaacaa atatttgttt ctactactag tgcctgctcc tcacgtaaac atatggcaag
    12181 cagtacattg cacgcaatgc atgtaccaaa tgatctggct acatctgctg ttcgaatcag
    12241 cttagatgaa aacaattcgc ttgcagaagt cgagcaattt atgattattt tcaagcagct
    12301 ttataagaaa ttttctgcaa tcaattaaaa gaggagtgtt cttgtgaaat acagtgaaat
    12361 tatggtccgt tatggggaac tttcgacaaa aggaaagaat cgaaaaagct ttatcatgca
    12421 actagcacaa aatgtcagac aagctttgaa agactttcca gaaatcaaaa tccatgctga
    12481 tcgggaccgg atgcatcttt tattgaatgg cgcagacggg cagctagtta ttccaaaact
    12541 agcaaaaata tttgggatcc aaaatttctc tccaagtatt cgtgtagaaa aagatgtcga
    12601 agttttgaaa caagctgttc aagacatcat gaaagaaatt tatactggga aagaaacatt
    12661 taaaattatc gctaaaagaa gcgatcacca atttgaattg acaagtaatg aattgaatca
    12721 aacattaggt aatgctgttt ttgatatttt cccgcatatc caagttcaaa tgcgtcaacc
    12781 agatattcca ttacgtgtag agattcggcg tgatggcgct tatctatcgt atgaaacgat
    12841 caagggagct ggaggattgc ccgtaggaac aagcggaaaa ggaatgctta tgctttctgg
    12901 ggggattgat tctcctgtag cagggtactt tgccatgaag cggggagtgg aaattgaagc
    12961 tgttcatttt gctagtccgc cgtatacaag tgaacaagca ctgcaaaaag caaaagatct
    13021 aacagccaaa ctagcacctt atgtgggaac gatccatttt atcgaagtgc catttaccga
    13081 gattcaagaa gaaatcaaaa agtcagtgcc acaaggatat tggatgacaa ttactcgtcg
    13141 aatgatgttg cgtttgaccg atgaaattcg ccgtattcgt catggtttag tcattttgaa
    13201 tggtgaatca ttaggtcaag tggcttcaca aactttgcaa agtatggtgg ctatcaatga
    13261 agtaacgaat acgccaatca ttcggcctgt agcgacaatg gataaacttg aaatcattga
    13321 agtagcagaa cagatcgata catttaatct ttctatccag ccttttgaag attgctgtac
    13381 gatttttgct cctccacagc caaaaacacg ccctcaactg gaaaaggtcc atcaatatga
    13441 agagcgttta gcaatagatg aaatgatcca acgagcacta gctggcttga agatggaaga
    13501 gatacaagca gaatcgtcta atgaaaaaac tgaagaattt tcagaattgc tataagaggt
    13561 tatgaaaata gtgttttgac cagagtatta gagaaacaaa acgaaaaaat agctccatgt
    13621 attttaccgt ttttgaacta atgtcgaaga ttagctgatt gaataccatt tatcaagaag
    13681 ttatggaaaa gccggttctt ttttactaac tgaaaaataa aattttattt agagatcaag
    13741 ctacagttga taaatgatat aaaaaagaga atttcccatg aaatagcgag gttgtgacag
    13801 aagtgggcag cttcaagaaa taagaaggaa tttacgaaaa ttgcttttca aatttttgtg
    13861 aaatttcggc ttatttttcg aagaagttac ttctggaaca ccgtgtatca gaggttgcga
    13921 aaaagctgcc ctgcatcaag taataagaac agccaaacaa aaatagttcc tcatatttta
    13981 cgtttggttg agcttattac cgcagatgca agcttttgaa caccgtttta tttgtctcac
    14041 acccttttcc ttcctacttg taaccttgct cccgtgttag aaacatgtta cactaaatat
    14101 gtgaaattat taacaaggag cgtcgttatg cgagaaaaaa cagatacact gccaaaagca
    14161 actgcgaaaa gattaccttt atatttacgc tacttgaaga tgctggatga ctcaggtata
    14221 agtagaatca aatcaaatga gttcagcgaa atcacccaaa ttccttctgc aacgatccgc
    14281 agagacttct cgcaattagg cgagctaggc agaagcggat atggctatga tgtccctttt
    14341 cttatcgatg tattcaataa tatccttaat actaaagaag aaaaacgaat cgcattagta
    14401 ggatatggaa atcttggcaa agcattgaaa cacaacaatt ttagaagaaa tgaaaatcta
    14461 aatatcgtgt gcgtctttga taatgatcca gcactgatca atcgagtaat tgatggagaa
    14521 atgatctatc cgattgatcg tttcgcggag atagccaaag caaaaaatgt gacagtagca
    14581 atctctacgg taccaagtaa atattcacaa tctgctattg atgaaattgt caaaggaaat
    14641 gtaaccgcta tacttaattt tgcgcctgac agagtaactg tcccagctta tgtcaatgtt
    14701 caatacattg atttgacaac cgagttgcag acgcttattt actttgatga gaattactca
    14761 gaagtttttt cttaggaaaa tttgagtagg cttattgatc ttgcgagaac tcgtcgtaat
    14821 tctttcaaaa attttttagt actaaatgaa gtggtttttt cacgaccact tgttgactaa
    14881 aaaaaaaaac cattgtagaa tgaagcataa cgctgaacaa gaggagtaac tggcacattc
    14941 attcttagag agagaactat ctgctgaaag gttctcaatg acaaccagtg aaggtagctt
    15001 gggagtttct gtcttgaatg gagtagagat agacgagtcg tgatcgttaa ctcacttgag
    15061 aggcaataat gattgattat tgcaatttag gtggtaccgc gtaaatcata cgtcctagaa
    15121 tacgaaagta ttttaggacg ttttttagtt taaaggagga aaacagcatg acggaagaaa
    15181 ataacctatc aacaaaatat aatccgcaag aagttgaagc tggacgttat cagcattggt
    15241 tagaacaaga tttgtttaaa ccgagcggag ataaaaaagc aaaaccttat tcaatcgtaa
    15301 tcccgccccc aaatgttact ggaaaacttc atttagggca tgcttgggat acgaccttgc
    15361 aagatatgct gattcgtcaa aagagaatgc aaggatatga tactttatgg ctgcctggta
    15421 tggaccatgc aggaatcgcg acacaagcaa aagtagaagc gaagcttaga gagcaaggga
    15481 tttctcgtta tgatctaggt cgtgaaaagt tcatcgatca agtgtgggaa tggaaagaag
    15541 agtatgcgag ccacatccgc gaacagtggg ctaaaatggg cttatcttta gattacagta
    15601 gggaacgttt tacattagat gatggattat ctgaagcagt acgtaaagtt tttgttacct
    15661 tatacgaaaa aggtttgatt tatcgtggtg aatatatcat caactgggat cctcaagcac
    15721 gaacagctct atctgatatc gaagttattc ataaagatat cgaaggcgcc ttttatcata
    15781 tgagctatga actagcagat ggatcaggcg tagtagaaat tgcgacaacc cgtccagaaa
    15841 cgatgttggg agatacggcg attgctgttc atccagaaga cgagcgttat caagcgctca
    15901 tcggcaaaaa agtgattcta cctttagtca ataaacaaat cccaatcatt gcagatgaat
    15961 atgtagatat ggaattcggg acaggtgtag taaaaatcac tccagcacat gatccaaacg
    16021 actttgaggt aggtaatcgt catgatcttc cacgcgtaaa tgttatggat gatgatggta
    16081 cgatgaatga actagcagga aaatatgctg gaatggaacg ttttgctgct cgtaaagcaa
    16141 tcgtgcaaga tctgaaagaa atcggtcgat tgattaaaat cgatacgatg atccacagtg
    16201 tgggtcattc cgagcggaca ggtgtcgttg ttgaacctcg gctgtctact caatggtttg
    16261 taaaaatggc gccgttagcg aaaaaagcca ttgataacca agaaacagat caagcagtgg
    16321 aattcttccc tccaagattc aatcaaacgt ttttacgttg gatggaaaat gtccatgatt
    16381 gggtaatctc acgacaatta tggtggggac atcaaattcc tgcatggtat cacaaagaaa
    16441 caggtgaaat gtatgtaggg atggaagcac cagcggatag tgaaaactgg gtacaagatc
    16501 ctgatgtttt agacacttgg tttagttcag ctttgtggcc tttctcaaca atgggctggc
    16561 cagatacgga aagcgaagat tataagcgat acttccctac tagcacttta gtaaccggtt
    16621 atgacatcat tttcttctgg gtaagcagaa tgattttcca aagcttggaa tttactggcg
    16681 aacgtccatt tgagaatgtc ttgattcatg gattgattcg tgacgaacaa gggcggaaga
    16741 tgagtaaatc attaggtaat ggaatcgatc cgatggaagt aatcgaaaag tatggagcag
    16801 atgctctccg ctggttctta tcgaatggtt ctgcaccagg acaagatgtc cgcttcagct
    16861 atgaaaaaat ggatgcttct tggaacttta tcaacaaaat ctggaatgct tcacgtttcg
    16921 ttatcatgaa tatcgaagga atgaccgtag aagagatcga tttatctgga gaaaaatcag
    16981 tggctgaccg gtggatcctt actcgtttga atgaaacgat cgaacgagta actgagctat
    17041 ttgatcgttt tgaatttggt gaagcaggtc gacaactgta taactttatc tgggatgatt
    17101 tttgtgactg gtacatcgaa atgagtaaag aagtacttta tggagatgat gctgtttcaa
    17161 aacaaaccac ccgtagcatc ttagtccata cacttgatca gatcctacgt ttattgcatc
    17221 caatcatgcc attcgttaca gaagaaatat gggaacatat tcctcatcag ggaaattctc
    17281 tagtagtggc agaatatcct gttgtacgtc cagagtttga tgatgaaaca gcttctaaag
    17341 ggatggaagt attgaaagaa ttgattcgag ccgttcgaaa tattcgttca gaagtgaata
    17401 caccattgtc taaaccaatt acgttgctaa ttaaaacaaa cgatgctaaa atcgatcaat
    17461 ttttagttga aaatacaagc tatatcgaac gcttctgtaa tcccgaagag ttgacgatat
    17521 caagtgagat cactgcgcca gatctagcga tgtcagctgt tctgacaggt gcagaaatct
    17581 tcttgccgtt agcaggattg atcaatattg aagaagaaat caaacgatta gaaaaagaac
    17641 tggaaaagtg gacaagcgaa gtaaaacgtg tccaaggaaa actttctaat gaacgttttg
    17701 tttctaacgc gccggaagaa gtagtagagg cagagcgtgc aaaagaaaaa gattatttag
    17761 agaagcaaac ggctgtcaaa gaacgaatcg aaagtttgcg tactattcaa taagaataga
    17821 aaaagagagt gtgaaatcag ctagctatta ctaaaagcta gctgattgaa catcgttaca
    17881 ggaaagagtt tgagcctcac tcttagcttc gattcataag gagatgtgac ataaattttg
    17941 tcgcatctct tttttagtct actcttatta tgtaggagaa ggagggaggt ggatcatgta
    18001 tcaagagtca ataaagtagt tgataaaatc gttcctctct ctgtttcttt tctctttgtc
    18061 atacttttat ttttcttatg tgttctattt gttataataa aagagaaatg ggggaattgt
    18121 tgatgacgat tgaagaagca atagaatgga tccatagtcg attaccattt ggttcacgtc
    18181 ctggccttga ccgagtcgaa gctttattag aagtggtagg gcatccagag agaaaagtaa
    18241 aaacgatcca tatcgctgga acaaacggaa aaggttctac tgtagcttat ttgagaagcc
    18301 tattagaaga ggctgggctg acagtaggta catttacttc accttatatc gaaacgttca
    18361 atgaacggat cgcaatcaat ggcaaaagca ttccagacaa tgatttgatc cagcttgtaa
    18421 aaaaatatca gccactgatc aaacaacttg atcaatttga agcagtagct ggtattactg
    18481 aattcgagac attaacagca atggcatttg attatttttt gatgaagaaa gtggacgtag
    18541 cgattatcga agttggctta ggcggcttat tggattctac caatgtagct gtaccaatgc
    18601 tgacgggaat aacaacgatt ggacttgatc ataccgaaat acttggagat acaattgaag
    18661 aaatcgctgc acaaaaagct ggaatcatca aacaaggcgt tccagtagta acaggaaata
    18721 ttgccccaga agcttttact gtcatccaac aaacagctaa agcaaaaaat gcaccgcttt
    18781 atgtatacgg ggaaaattat aaaataaact atctgcatcc tgatgagatg tggggagaag
    18841 tatttgaatt ttttaatgaa ataggaaaga tccctcaatt aaccactccg cttttagggc
    18901 aacatcaagc tgaaaatgca ggagtagcca tcgaattgta ttttgtttac tgtcaattgg
    18961 aaaagctgcc tttccgagaa aaagatgttt tgaagggatt gaagaaatct cgatggccag
    19021 gaagaatgga gcgtttgagt aacgagccat tagttgtttt agatggtgcc cataatacgc
    19081 atgcaatgaa ccggcttgtt gagaatttga aaaaagaatt caaaggatat caaatcaaca
    19141 ttttgttttc cgccttacga actaaaaatg ttagagaaat gctagaacga ttgcagcaag
    19201 taccaaatgt ccatatttat ttgacgacct ttgaacatcc aaaagccatc gaattaagtg
    19261 aagtatcaga tttagcaagt gagagagtat caatcgtttc attgtggcaa ttcggattag
    19321 cagatatatt ggaaaagatg acaaatgaag acgtattagt tgtgaccggt tcactttatt
    19381 tcatttcaga agttcgccat ttattaatac aattaggagg agatcatgaa gtataatgca
    19441 gtgatttttg acatggatgg tttgctgttc gacacagagt tagtgtatta cgaagccaca
    19501 caagtagtag cagacaagat gggttttcct tatgataaag acctgtattt aaaattctta
    19561 ggtgtttcag atgaagaagt atgggcgaat tatcatatga ttttctcgga atttggcaaa
    19621 acaagtgtac aaagattcat agatgattca taccaggaaa cgcttgaacg tttttcgcaa
    19681 ggagcggtac aaatgaagcc cggtgtgttg gaactcctct cttttttaga agaacatcag
    19741 attcccaaag ttgtcgcttc cagtaaccaa cgagcagtca ttgaactttt attgaagaag
    19801 aacaatctgt ttgaacgatt tgagacgatt gtttctgcag aaaatgttca acgagcaaaa
    19861 ccagacccag aaattttctt gttagctaat cagaagctag gtacagcgaa gaaagaaaca
    19921 ttgattttag aagattcaca aaatggtatt ttagcagctt ctgcggctga gatcccggta
    19981 gtcatggtac cagatctgct tccaccatcc caagaattga tcaaaaaaac agctggggtt
    20041 gtttcttctt tacatgaaat ccctgcattg ttaaaataaa aatccatctc ttttcgtatc
    20101 ttattttaga taagatagaa aggagatgtt tttttgggaa aacgattgat caaagaagta
    20161 cctactagct ctttaccaag ggaacgtatg gaaatttatg gcgcggaagc tttatcggat
    20221 caggagcttt tggcaatctt actgcgtacc ggtcaacacc cttatagtgt gatgtcgatt
    20281 gctggaaatc tgttaaaaac gtttggagga ctggcctctt tacgacaggc tactttgcat
    20341 gagttagaag agattcgagg gataggacgc gtgaaagcaa tcgaaatcaa agccttgatc
    20401 gaattaggtc gacgaattca gacggatcat gaaagagcgg ctccaccggt tcgtaccagc
    20461 tacgaattgg cccagcaatt gattctggaa atgaaagatc acaaacaaga acatttggtt
    20521 tgtatttatt tggacacgaa gaatcaagtg atcttaaaaa aaacagtgtt catcggttcg
    20581 ctgaatcagt cagtcgctca tcctagagaa attttccatt atgctgtacg ttattgtgca
    20641 gcaaggatcg ttttagcgca taatcatcct tctggtaatg ttattccatc gcagcaggat
    20701 atgaatttta ccaaaaggat acaaaagtgt ggagaaatga tggggatcac tgtactggac
    20761 cacttgatca tcggacgcaa acgatatttt agtttgagag aagaaggaat gatggaagag
    20821 aagtaagttg ctttcttgca aaaaaaatga agcaagtgta caattatatt gtaattttgt
    20881 ttgggaatag aagttgaaac atctgttgca cctctatcgt acacgagcaa tgttacaatt
    20941 taaattagtg cttttggcac gaggaggata ttattatgga aaacggaaca gtaaaatggt
    21001 tcaacgctga aaaaggattt ggatttatct cacgtgaaga tggaagcgac gtattcgttc
    21061 acttctcagc tatccaaggt gacggattca aaacattaga agaaggtcaa gcagtgactt
    21121 tcgacgttga agaatcagac cgcggcccac aagctgcaaa cgttgtaaaa gcttaatttt
    21181 atctgtaaat caaattgatg gtagacatca atttttacga gagaacaaag cgagtaacaa
    21241 aaatacctgc cacaagagac aatttctctt gtggcaggta tttttttgta tgaaaaagta
    21301 aataaattta agaggctatg aaagagccac cttgtatcaa ggaataagaa caaacaaaaa
    21361 tggcttctca tgtttttcat ttgttttctc ttatattcag gacaaggtgc tgatttcata
    21421 acctcttatt tattcttcat ctggtgtcat taccattggc aaaatcattg gatgtctttc
    21481 tgtacgttcg aataagaaag gctgaagcgc gccagtcatc gcttctttca atttatattc
    21541 tgaacagtca ggtccattca aacattctct taaagcgtgg aataagattc gctgagcttc
    21601 attgatcatt tctcctgatt ctcgcatgta gacaaatcca cgagagagaa tatctggacc
    21661 agccaagatt tcttttttct tgatatccac tgtcgcgaca gctaatacaa gaccttcttc
    21721 tgaaagcagg tgacggtcac gtaaaacgac attaccaata tcaccgatcc cgctaccatc
    21781 gatatacaca tctccagcca caaaatgccc agcaggacgc gcagaatcgc tagttaacgc
    21841 taaaacatcg ccattttcca tgatgaagca gttttctgca ggaacaccta catcttgtgc
    21901 tagagaagca tgtactttca acatgcggaa ttctccgtgg acaggaataa aatattttgg
    21961 cttcatcaaa cgaagcatta atttttgttc ttcttgtcca ccgtgaccgg aagtatggat
    22021 gttattgatt tttccgtgaa tcacttctgc accagcttca gacagcaaat tgatcaaatg
    22081 attgacactt gttgtattac caggaatagg tgaacttgaa aagatcactg tatcgtctgg
    22141 ctggatttgg atttgacggt gagtaccatt cgcgatgcgg ctcaacgcgg ccatcgcttc
    22201 tccttgagaa cctgtacata ggatcatcgt ttcattggca ggcaagcgat tgatttcgtg
    22261 tgcatctaca aatgtgccgt ctggaacttt gatatatcct aaacgttgac cgttgacgat
    22321 ggcattttcc atgcttcgtc cgaaaacagc gattttacga ccagttgcca cagcggcatc
    22381 tgctgcttgc tgcaaacgga agatgttaga agcaaagctg gcaaaaatga tacgtccttc
    22441 gatttttgaa aagatcttca aaatagaatg cccaatcgtt ttttctgatt tagtaaatgt
    22501 tggaatctca gcatttgtac tatcagataa aaggcacaag actccttctt ccccgatacg
    22561 agccatttta tgcaagtttg ctggttcgcc aacaggagtg aaatcgaatt tgaagtctcc
    22621 agtcgctacg atatttccag aaggtgtttt caccacgatc cctaatgcat ctgggatact
    22681 atgggtcgtt ctgaaaaagc tgacagaagt ctttctaaaa cggatgatcg tatcttcatt
    22741 gatctcatgg agctctgcat ctcgaagcaa gccatgctca tctaatttgt ttgtgatcaa
    22801 cgctaatgcg agaggaccag catagatagg aatatttgct tgtttcagca agtagggtat
    22861 tccgccgatg tggtcttcgt gcccgtgagt aatcaccaag gcttttactt tgtgtaagtt
    22921 ttgtatgatg tagctgtagt cgggaatgac atagtcaatt ccaagtaaat cgtcttccgg
    22981 gaatttgatc ccggcatcaa tcaaaatgat ttcatcttgg aattgtaccc catacgtatt
    23041 tttcccgatt tcacctaatc caccaatagc aaagacgcct gtctcgttat ttttgatgga
    23101 aagtttcata ttaaaactcc actaatgaga aatcagcatt ttctttttcg tactctagat
    23161 gacttccttc tagaagttga acgaattcaa tattgtatgg ggtattttct tccacacgtt
    23221 ggcgagcgtc tacatcgctt tttgcctcaa tgtaaagaga ttttgtttct tcccgtttag
    23281 ggttgcgtac ttttgtttct tgataataaa ctttatagat cattgttttg tctcctttat
    23341 ctgcgtaaag cagtgattta gctagttgat ttttttagac aacacaaaac gaggggacaa
    23401 gccacctggt ttttcatatg ctttgactag aatactggat tcgagtcaaa gagacaagcc
    23461 tcgtttttgc ttatctgttc ggatattttt tcaaccgtac cttctgtata aaaaatatac
    23521 aacaattaat tgttattcta gcataaaaca gcaaataagt atagaaatca actagattga
    23581 aagaaaaaat caatgtttat catcccgcta taatcataat gactttttta tgagagaagt
    23641 gttctattaa taggctcgtt gtgctatcat ttttagtaat gaaaatgtaa caaaagatta
    23701 aaaggagatg agaaagtgaa actaatgtgg cattatacca tgcgttataa gaaattcttg
    23761 tttttcaatt tcatatgcgt atttggtttt attttgattg aattaggact tcctacgatt
    23821 ttagcacgta tgatcgatgt aggaatccgc aatgatgatt ttgattatgt gaagcaacaa
    23881 gggatattta tgatcgttat tactgtaatc ggtattattt tgaatatctt gttaggttat
    23941 tttggttcga ggattacgac taatatcgta gcagatattc gagatgattt gttcgaaaag
    24001 atccaaagtt attcgcatca ggaatacgaa aatctaggcg tatcttcatt gatcactcgt
    24061 acaacaaacg atgcttatca gatcatgttg ttcctgcaaa atattttacg tatcggtttt
    24121 atggcaccaa tgatgttcat tgtcagtttg tacatggtca tgcgtacaag tgtgacactc
    24181 agtttgtatg tagtaggtgc attaccttta ctattattgg cagtcgtagc gattgctaag
    24241 gtgtctgaac cgttatctaa aaagcaacaa aaaaacttag ataaaatcaa cagtatcttg
    24301 cgggaaaatc tttcaggatt gcgtgtgatt cgtgcattcg tcaatgaaaa gtttgaagaa
    24361 aaacgttttg ctgtagtcaa tgagaattat gcttctagtt caaaaagctt attccgtttg
    24421 atggctgttg cacaaccggg tttttatttc ttatttaata tcgtaatggt attgatcatc
    24481 tggagcgggg cagtgcaaat cgatgcaggc gagcttcgtg taggagattt gattgcgttt
    24541 atcgagtata tattccatgc cttgttctca ttcatgttat ttgctagtgt gttcatgatg
    24601 tatccaagag cagctgtttc agctggacgt atccaagaag ccctagatgc caaaccttcg
    24661 attgtagaag atccaaatgg tatatctgat acaaaaacta aagggtatat cgaatttcaa
    24721 aatgtaacat ttgcttatcc aggccattcg caagagccag tgatacgaaa tgtcagtttt
    24781 acagcctctc caggagagac cgttgctttt attggaagta ccggtagcgg aaaatctacg
    24841 ttgatccaat tgatccctcg cttttatgat gtgagtgaag gaaagatctt gatcgatgga
    24901 gtagacgtga gagattatcg gctaagcaag ttgcgagata agattgggtt tattccgcaa
    24961 aaagcgctgc tatttactgg aacgattgca gataatttgc gatacgggaa agaagatgct
    25021 acgcaagaag aaatggaacg tgcagctgag attgctcaag cttcagaatt catttctcga
    25081 aaaccagatg gatttaatga acatttatca gaaggtggtt ccaatttttc aggtggacaa
    25141 aaacaacgat tggcaatagc cagagccatc atacgccgtc cggaaatcta tatttttgat
    25201 gacagctttt ctgcattaga ttatcaaacg gatgcgaagt tacgtgctcg tctgaaaaaa
    25261 gaaacgacag aatctactgt attgatcgta gcacaacgtg tgggaacgat catgcatgca
    25321 gataagatca tcgtattaaa tgaaggagaa gtcgtcggta tggggacgca tcgggagttg
    25381 ttggaaaaat gcccgattta ttatgatatt gccgcttctc aattatcaaa ggaggaatta
    25441 gcatgaaaaa aaccttttct tccttaaaac gtttagctcg atatatcaga ccgtatcgtg
    25501 agacttttct tttagtgatc ctatttacag ttctgacagt ggctttcaac gtggctttgc
    25561 catatgttac aggacttcct actacagaaa tcagccgtaa tattgccaat ggcgaatcaa
    25621 tcaatttttc ttatatattc aaatgtctca tttggatcac agttgttgga atagggtatt
    25681 gtatttcgca attactttct ggtgttttga tgacaaatgt cgttcaaagt gccatgcatg
    25741 atttgagaag agacatagaa gaaaaaatca atcgtcttcc ggtttcatat ttcgataaaa
    25801 accagcaagg aaatattttg tctcgtgtga cgaatgatgt agatgcagtc agcggtgctt
    25861 tacaacaagc ttttattggt atcgtaaatg cgatattggg aattacgttg gctgcagcaa
    25921 tgatgtttta tatccagccg atgatggcgc tgatctctat gatcatgatt ccaacatcga
    25981 tctggatctc aaaacgagtg atcaatgctt cgcagaaata ttttcaaagc atgcagaatt
    26041 ctcttggtga gctaaacggc tacgtccaag aaaatatgac aggttttagt gtattgaaag
    26101 tatatggacg cgaaaaagaa acattggaag gattcaaaaa agttaatcac agcttgaaat
    26161 actttgggtt tcgtgcagca ttcatttctg gcttgatgat gcctctagtt caattaactg
    26221 cctatgctac ttatattggt atggctgttc taggaagctt ttatgttatt actggggcga
    26281 tcgttgtcgg tcaactacaa gcattcatcc aatatatttg gcaaatcagt cagccaatgg
    26341 ggaacgtgac acaattgtct tcagttttgc aaagtgcatc agcggcaacg aaacgtgtat
    26401 tcgagatttt agatgagcca gaagaaaaag aaaacaaagt agatgcttca ctgccagaaa
    26461 cgattttagg agatgtgaca ttcgatcatg tcgattttgc atatgatccg aagaaaccat
    26521 taatccaaga tttgaatttt gaagtgaaag ctggtcaaac cgtagctgtg gtcggtccga
    26581 ccggtgccgg caagacgaca ttgatcaatc tattgatgcg tttttatgac gtagacaaag
    26641 gagcaataag gattgatgga atcgacacca aatcaatgag tcgcagtgat gtgcgttcgc
    26701 tatttggtat ggtcttgcaa gatgcatggc tttatcaagg aacgattgca gataatatcc
    26761 gcttcggaaa gcttgatgcg acagattatg aagtagttga tgctgcgaaa acagcaaacg
    26821 tagatcattt tatccgaacg atgccagatg gatatgatat ggccatcaat tctgagggag
    26881 acaatgtgtc tttaggacaa aaacagttgc tgacgattgc ccgagcagtg gtctccgatc
    26941 ctaaaatctt gattttagat gaagcaacaa gttcagtaga cacccgttta gaagcgttga
    27001 ttcaaaaagc aatggatcgc gtgatggagg gacggacaag tttcgtcatc gctcaccgtt
    27061 tatcgacaat ccgtgatgca gatctgattc tagtgatgga tcaaggtcag atcattgaaa
    27121 aaggaacgca tgagagttta ttggcacaag gtggatttta tgaaaaactg tataacagcc
    27181 aatttgctga ggaagcagaa taagtcatat aagaataaaa cagtttaaaa cttatttttt
    27241 gttctctatt cttgataatg gtaaagtaaa gttatcaaga aaagtgagga cacggagatg
    27301 gaacagtttt taaatgaaaa aattactgaa gccaaaagag aagttgatcg tttaacgcac
    27361 gtctgtcaga cgaagccttt tgattcagct gatttttttg aaaatgagtt tcaaatcgaa
    27421 cgcttggcag cacaaataga agtgtacgaa ttaattttaa aaaaagtaat agaagaaaat
    27481 atagatgtac aataaaaaca ggtaaaacgt cagttaccag atactgtaaa tagacatctg
    27541 gcctgagcag gttttacctg ttttttttct tatgaaataa atatatgcta tgataccttt
    27601 attcaatagg attagtttct acaaaaaatg aaaggagaaa aataaatatg gaacggttta
    27661 tagcatcaaa tgccacagtg attggtgatg tgacattgtc agaagatgtg acgatctggt
    27721 atcaagctgt tttacgcggg gacagtaatt ggataaaaat aggacaaaga acgaatatcc
    27781 aagatggtac aatcatccat gtcgatcatg atgcacctgt agatattgcg gagaatgtga
    27841 cggtaggaca tcagtgcatg ctacatggct gtacaatcga aaaaggggcg ctgatcggga
    27901 tggggaccac gatattgaat catgcggtta ttggtgagaa tagtttgatt ggtgctggat
    27961 cattagtaac agaaggaaaa gttattcctc ctaatgtctt ggcttttggt cgcccagcta
    28021 aagtgatccg tcctttgaca aaagaagaaa tacaaaaaaa caaagaaaac atccagcatt
    28081 atgtcgagat aggtcggatg catgcgcaag gaaaattcaa ggagcaaaga taggcagtag
    28141 catccataaa ataaaaaagg atggtcagtt tgagttgacc atcctttttt atttggttta
    28201 gataagagag cttaaaaaag cttcctttga aacagattaa tttaatgaag aactgttttc
    28261 catgacttca tcgatcaatc catatgcttt tgcttgttca gctgtcatat agttgtcacg
    28321 atctgtatct ttttcaatca cttcaagcgg ttgtccagtg cgttcagcta aaattttgtt
    28381 taagcgttcg cgtgtttgca aaatatggcg tgccgcaatt tcgatttcag ttgcttgccc
    28441 ttgagcgccg ccaagaggtt gatggatcat gatctcagca tttggtaaag caaatcgttt
    28501 accttttgta ccagctgtca gcaagaagct tcccattgaa gcagccatac ccataacaat
    28561 tgtttggaca tctgctttga caaagttcat tgtgtcgtaa atagccatac ctgctgtaac
    28621 tgaaccacca ggagaattga tataaagata gatatctttt tcagaatctt gagcgtctaa
    28681 gaaaagcaat tgggcgatga tcgaattagc aagatcatct gttacttggc cgcttaacat
    28741 gatgatacgg tctttcaata aacgtgagta gatatcgtaa gctctttcac ctcgtgaaga
    28801 ttgttcaatg actgtaggaa ttaaattcat aatagagttc ctccttgatt tcgtttagaa
    28861 atagtgtacc ataatttagt ttctaatacc taaaatgtag tatacatttt tggtcaaaaa
    28921 aggtcaaata aaaaacttag gcaaattagt cgcataaacc cgctttatgg tatgataagc
    28981 agagaaacaa aacaaggagg aacaacagat tgatagttgg tattactggc cttatcggag
    29041 tgctgacagg tgctgtagtt gtctatatcg gcatgatact gcaaatgcgt cacttggaaa
    29101 ataaagaaca gcgtagacgt gaattggaat tgaaagtcaa agaaatcgag acgctgaatc
    29161 aattaaataa aaagatcaac gagatcttgc aaaaacggac aacgctgatg gaagaatatg
    29221 tcagctttga tgcatttgat gattgttata tcacgattga cgattttgcg tatctccaat
    29281 cattttcagc gcaaaatagt ttttatctgc caaattatat tttagacgag ctatttaaga
    29341 atatctccca tcgaaaagtg attttatctc cagatgaaac aatgaagatt ggtggatatg
    29401 cttataaagg cggacgcgtg attttagaga attttacgga tagtctgact gaaatgatca
    29461 atgaaaaaaa agctcagttg aagactatga cgcgccagcc gattggtttc ttctcgaaag
    29521 atgatgtttg gagctgatat tttgaagcat tgccgttgca catgagagcg tggtaatgct
    29581 ttcttttttt cttaatgata caatagaact gaacggagtg aagaaagatg ttacaaatct
    29641 atgcccatcg cggaagcagc ggcacccacc cagaaaatac gcttcctgca tttgcagaag
    29701 ctgtacgagt aggtgcagat ggtatcgaac tagatgtcca tctaagcaaa gatggttatt
    29761 tgatcgttat gcacgacgaa gaagtggacc ggacgactaa cggtaaaggg ctgattcgag
    29821 aaaaaacatt ggaagaactc aaaaaattga atgcaggggg caaattcagc aaagaatttc
    29881 cagcagctaa agttcctgaa ttgagagaag tgttaggact gctcctccaa aaaaattacc
    29941 gagggatgct aatgattgaa attaaaactg atcagtatga atatcccggt atcgaagaaa
    30001 aattagccga aacattaaaa agtagagatt ggccttttca acatgcatat tgcagctttc
    30061 atttggattc tttggaaaaa atcgcattac tggaaccgga gatacagctg gacttattga
    30121 tgagtacttc tgataaaaag atccaactag cagcagaaac cccttatata gaaggagtac
    30181 atccaaaaaa tacttggttg ttcgaacatc cagtccaggc agctgatttt ccaaaagcaa
    30241 ttcgtgcatg gacgattaac gatgaagaag aaatggccaa atgtcaagaa ctcaaaatag
    30301 atggaataat aactgatttt ccggagaaag ctcttcggtg gaaacaatca acgaaaagta
    30361 ggtaaaatat ggaaaaagta ttagtgatcg tcggtccgac agcagtcggt aaaacagcgc
    30421 taagtgtgga actcgcacaa ctatttggag gagagatcat cagtggtgat tcattgcaaa
    30481 tctataaaaa tctggatatc ggtacagcaa aaatcaaaga agaagagatg aataatgttc
    30541 cgcatcattt gattgatgtg atcgaaccta ctcaacgtta ctcagccgct gattttcagc
    30601 attcaggtcg acaattgatt accgagattg cgaaccgagg gcacctacct atcatagctg
    30661 gtggtacggg tctctatatc caatcccttc tatatgatta tcagttagga gcgacagaag
    30721 aagcgaatcc tgagattaga aaaaagtatg aaacgttagc tgaaacaatt ggttcccaag
    30781 cattatggaa tcagttgaaa gaaaaagacc cggcagctgc tgagaaaatc cactggaaca
    30841 atcaacgcaa agtgataaga gctctggaag ttttagagac gacaggacat agtatcacgg
    30901 cacctaaaga agagccaaag caattgtatg attacctcat gattggatta gatacgaagc
    30961 gtagtattct ttatgaacga atcaatcaaa gagtcgattt gatgctagca gaaggtttag
    31021 tagcagaagc gcgtaaggtg tatgagcttg gagaagtcca ggccagtcaa ggtattggat
    31081 ataaagaatt tttcccttat tttgaaggga aagaaacatt ggaagaagca acagaacaag
    31141 tcaaactaca ttcgagaaga tacgcgaaac gtcagttgac gtggtttcgt aaccgtttgg
    31201 atgcacagtg gtttgatctt ataagtgagc caaatcaaaa aagtcagatt gagcaaacaa
    31261 tcaaaaaatg gctggaggcg gaataaaatg gaagaaaaag tgatcatcgt aggggtagaa
    31321 accgaagcaa accagcgtta cttttcagag tcaatggaag agctagttca gctgacgaat
    31381 accgcatcag gagaagtcgt attcacaatt acacaaaaga gaccacaagt ggatcggcaa
    31441 acgattatcg gtaaagggaa attacaagaa ttagttcaac aagcggatgc gcatgaagcg
    31501 gatttgatca tctttaatca tgagctaact ccgagacaga gccaactgat taccgatgct
    31561 gttggtcttc cggtaattga tcgcgtgcag cttatcttag atatttttgc gatgcgtgct
    31621 cgttcgaaag aagggaagct gcaggttgaa cttgctcagt tagaatacct gctgcctcgt
    31681 ttagtagggc aagggaaaac attatctcgt cttggcggtg ggatcggaac aagagggcca
    31741 ggtgaaacaa agttagaaac agaccgccga catatacgga ataaaatttt tgctgttaag
    31801 aaagaattga aagaagtaga agctcatcga gagcgcaatc gccaaaaaag aaaaaatagc
    31861 gagatttttc agattggact tattggctac acgaatgccg ggaagtcaac tatcttgaat
    31921 ctattgacac aagcggatac ttattcgaaa gatcaattgt ttgcaacgtt agatccattg
    31981 actaagagat ggcgttttgc tgaaggattt gagattactg taacggatac cgtcgggttc
    32041 atccaagacc tgcctacgca actgatcgat gctttccatt ctacattaga agaaagtcaa
    32101 aatatggatc ttttgctaca tgtagtcgat gctagttctc cagatcgtat tttacaggag
    32161 cagactgtct taaaattgat ggatgaactg aatatgaaag aaatgccgat actgactgtt
    32221 tacaataagg cagaccagat cgacccagcg atgttcacgc ctacgctatt cccaaatgta
    32281 ttgatttcta ctcagacgag agaaggtaag atggcgttga tcgaagcaat caaacgtcag
    32341 ctgatggaac taatgacccc ttatacactt tctgtgccaa gcaacgaagg acagaaatta
    32401 agcgagttga gaagacaaac aatggttttg gacgaagcgt acatggaaga aacaaacgaa
    32461 tatgaagtta aagggtttgc aaaaaccaat tcaaaatggt taagaaaaaa ccaataaaat
    32521 tttatttttt taa
//
LOCUS       DAXQKX010000028        30951 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.028, whole genome shotgun sequence.
ACCESSION   DAXQKX010000028 DAXQKX010000000
VERSION     DAXQKX010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30951
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.028"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            123..2564
                     /locus_tag="ACF3MF_001453"
     CDS             123..2564
                     /locus_tag="ACF3MF_001453"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HFE3927451.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(2894..3598)
                     /locus_tag="ACF3MF_001454"
     CDS             complement(2894..3598)
                     /locus_tag="ACF3MF_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927452.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(3785..4030)
                     /locus_tag="ACF3MF_001455"
     CDS             complement(3785..4030)
                     /locus_tag="ACF3MF_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927453.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(4047..4898)
                     /locus_tag="ACF3MF_001456"
     CDS             complement(4047..4898)
                     /locus_tag="ACF3MF_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFE3927454.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            5064..6068
                     /locus_tag="ACF3MF_001457"
     CDS             5064..6068
                     /locus_tag="ACF3MF_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HFE3927455.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            complement(6309..6665)
                     /locus_tag="ACF3MF_001458"
     CDS             complement(6309..6665)
                     /locus_tag="ACF3MF_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFE3927456.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            7033..8220
                     /gene="tuf"
                     /locus_tag="ACF3MF_001459"
     CDS             7033..8220
                     /gene="tuf"
                     /locus_tag="ACF3MF_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HFE3927457.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            complement(8408..10999)
                     /gene="mprF"
                     /locus_tag="ACF3MF_001460"
     CDS             complement(8408..10999)
                     /gene="mprF"
                     /locus_tag="ACF3MF_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HFE3927458.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(11025..11786)
                     /locus_tag="ACF3MF_001461"
     CDS             complement(11025..11786)
                     /locus_tag="ACF3MF_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFE3927459.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            11953..12585
                     /locus_tag="ACF3MF_001462"
     CDS             11953..12585
                     /locus_tag="ACF3MF_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HFE3927460.1"
                     /translation="MKRKRLSIIRILFYMIILTVIGAVLFLGGRTYRSVKRVESYQIE
                     ITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSESLHGEAEIIDNPADSIDQGVK
                     YLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHGGENTVELAEAYSKDVLSPLLG
                     NEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKMNEKIIETYEKVFK"
     gene            12644..13504
                     /locus_tag="ACF3MF_001463"
     CDS             12644..13504
                     /locus_tag="ACF3MF_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HFE3927461.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            13689..16004
                     /locus_tag="ACF3MF_001464"
     CDS             13689..16004
                     /locus_tag="ACF3MF_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFE3927462.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            16186..18027
                     /gene="dnaG"
                     /locus_tag="ACF3MF_001465"
     CDS             16186..18027
                     /gene="dnaG"
                     /locus_tag="ACF3MF_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HFE3927463.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            18051..19160
                     /gene="rpoD"
                     /locus_tag="ACF3MF_001466"
     CDS             18051..19160
                     /gene="rpoD"
                     /locus_tag="ACF3MF_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HFE3927464.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            19380..21479
                     /locus_tag="ACF3MF_001467"
     CDS             19380..21479
                     /locus_tag="ACF3MF_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division site-positioning protein MapZ
                     family protein"
                     /protein_id="HFE3927465.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            21675..22538
                     /locus_tag="ACF3MF_001468"
     CDS             21675..22538
                     /locus_tag="ACF3MF_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor B family protein"
                     /protein_id="HFE3927466.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYGFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            22643..23116
                     /locus_tag="ACF3MF_001469"
     CDS             22643..23116
                     /locus_tag="ACF3MF_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFE3927467.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            23212..24099
                     /gene="xerD"
                     /locus_tag="ACF3MF_001470"
     CDS             23212..24099
                     /gene="xerD"
                     /locus_tag="ACF3MF_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HFE3927468.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            24118..24489
                     /locus_tag="ACF3MF_001471"
     CDS             24118..24489
                     /locus_tag="ACF3MF_001471"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFE3927469.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            24486..25256
                     /locus_tag="ACF3MF_001472"
     CDS             24486..25256
                     /locus_tag="ACF3MF_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HFE3927470.1"
                     /translation="MNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDIPIATITEQY
                     MNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEEDPREELVTQ
                     LLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKKIDLIRAMQK
                     ILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESPSKSEVVTTF
                     MALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            25240..25809
                     /gene="scpB"
                     /locus_tag="ACF3MF_001473"
     CDS             25240..25809
                     /gene="scpB"
                     /locus_tag="ACF3MF_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HFE3927471.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            25815..26531
                     /locus_tag="ACF3MF_001474"
     CDS             25815..26531
                     /locus_tag="ACF3MF_001474"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFE3927472.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     regulatory      26613..26738
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            26861..27472
                     /locus_tag="ACF3MF_001475"
     CDS             26861..27472
                     /locus_tag="ACF3MF_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFE3927473.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     gene            27850..29373
                     /locus_tag="ACF3MF_001476"
     CDS             27850..29373
                     /locus_tag="ACF3MF_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HFE3927474.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            29610..30950
                     /locus_tag="ACF3MF_001477"
     CDS             29610..30950
                     /locus_tag="ACF3MF_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFE3927475.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
BASE COUNT        10358 a         5365 c         6526 g         8702 t
ORIGIN      
        1 agaaatataa aaaagagaat atttaaggat tgttaaaatt taatcttaga aaaaaataac
       61 tggaacaaga gctatttgtt tttacagcaa agaatggtat atttttgtag gaggtggctt
      121 acttgaaaga agtcgttatg atagatgctg caagaacgcc gataggaaag tatcgcggaa
      181 gtttaagtcc atttactgca gttgaattag gcacacttgt gactaaagga ttattagata
      241 aaacaaaact gaaaaaagat aaaatcgatc aagtaatatt tggaaatgtc ctgcaagctg
      301 gtaatggtca aaatgttgcc agacagattg ctttgaacag cggtctccct gtagatgtcc
      361 cagcaatgac gatcaatgaa gtttgcggat ctggtatgaa agcagtgatc ttagcacgcc
      421 agctgatcca attaggtgaa gcagaacttg tgatagccgg cggaacagag agtatgtctc
      481 aagcacctat gctgaaacag tatcagtcag aaacaaatga atatggtgaa ccaatttcca
      541 gtatggtcaa cgacggattg actgacgcat tttcaaatgc acatatggga ttaaccgcag
      601 agaatgttgc aacacaattt tctgtgagca gagaagagca ggatcgctat gccttgtcgt
      661 cccagttgaa agcagcacat gctgtcgaag ccggtgtatt ttctgaggag atcatcccag
      721 tcaagatttc tgatgaagac gtgttatctg aggatgaagc agttcgtgga aatagtacat
      781 tggaaaaact gggcacgtta cgtacagtat tctcagaaga aggaactgta acagcaggaa
      841 atgcttcccc gttgaatgac ggtgcctctg tggtgatcct tgcatccaaa gaatacgcag
      901 aaaataataa tctgccttat ttagcaacca tcaaagaagt agcggaggtc ggtattgacc
      961 caagtatcat gggaatcgct ccaatcaaag ccattcaaaa attgacagat agatcaggaa
     1021 tgaatttatc aacaatcgat ctttttgaga tcaatgaagc atttgcagct tcttctatcg
     1081 tagttagcca agaactgcag ttagatgaag aaaaggtcaa tatatatgga ggagcaatcg
     1141 cattaggcca tccaattggt gcaagcggtg cacgtatctt gactacatta gcttacggat
     1201 tgcttcgtga acagaagaga tacggtattg cttcattatg tattggtgga ggtttaggct
     1261 tggcagtctt gttagaagcg aatatggagc aaacacataa ggatgtgcaa aaaaaaaagt
     1321 tttatcagct tacgccatct gaacggcgca gtcaattaat agaaaaaaat gtattgacac
     1381 aagaaactgc gttgattttt caggaacaaa cactttctga agagctctcc gatcacatga
     1441 tcgaaaacca agtgagtgaa gtggaaatcc caatggggat cgcgcagaat tttcaaatca
     1501 atggcaagaa aaaatggatt ccgatggcaa cagaggaacc atctgtcatt gcagctgcaa
     1561 gtaatggtgc aaaaatctgt ggaaatatct gcgcagaaac acctcagcgg ctgatgcgag
     1621 ggcaaatcgt tctatcagga aaatcggagt atcaagcagt gatcaatgca gttaatcatc
     1681 gaaaagaaga gctgattctt tgtgcaaatg aaagttatcc ttcaatcgtg aaacgcgggg
     1741 gcggtgttca agatatctct actcgggaat tcatggggag tttccatgca tacttatcta
     1801 ttgatttttt agtggatgta aaagatgcaa tgggcgctaa catgatcaac tcgattcttg
     1861 agagtgtggc aaacaagtta cgggagtggt tccctgaaga agagattcta ttcagtattt
     1921 taagtaattt tgctacagaa tcattggctt ctgcctgttg tgaaatccca ttcgaacgct
     1981 tagggagaaa caaagaaatc ggtgaacaaa ttgccaaaaa aatccaacag gcaggggaat
     2041 atgcgaagct tgacccttac cgtgcagcaa cgcacaacaa agggatcatg aatggtatag
     2101 aagctgtagt ggcagctaca ggaaatgata cacgtgcggt tagcgcttcg atccacgcct
     2161 acgcggcaag aaatggatta taccaaggat taacagactg gcagatcaaa ggggataaac
     2221 tagttggaaa actaacggtg cctttggctg ttgccacagt aggcggagct tccaatatcc
     2281 tgccaaaagc aaaagcatct ttagctatgt tagatattga ttcagccaag gaactagcac
     2341 aagtaattgc tgcagtaggg ttagctcaaa acctggctgc tttgcgtgca ttagttacag
     2401 aaggaatcca aaaaggccac atgggacttc aagctcgttc attagcgatc tcaattgggg
     2461 ctattggtga ggaaatcgag caagttgcga aaaaattacg tgaagcagaa aagatgaacc
     2521 agcagacagc tatacaaata ttggaaaaaa tccgggaaaa ataaaaaagc aatatcttta
     2581 gaagaataaa gcaagattta cagttatttt atttactgca gatcttgctt ttttctctat
     2641 cagaaaatat gtttattatt agaatttttt atagttaagg ttaggcatct taagaaatca
     2701 ggcaactcca agatatcttc aggtagaaga gaagtcgcct aacattgtag gatcataggt
     2761 gatttgttgg acaggtcaag ctgatatttg agcctgatgt tagaaggaat ttctttttac
     2821 ttgctgtaga aattattata tgactaaaaa ggctgggatt ttaaatccca gccttttatg
     2881 acaaatagaa tttttatcga tcagtaatcg ctgtcgctgc aaattgttcg atcaaaggaa
     2941 tcaaagtcaa tttgactttg tatttccgtt cgagtgcttt ttcgataacg aactcatttt
     3001 cagtagtcat agaaatagtt gctaatttac gaggttcatc agcatttttt tcattaataa
     3061 ctacttcatg ttcattttgt tctgtgtaaa atttaggata ctcagcaacg gcttttgaaa
     3121 aatcagcaaa acttaaagcg gcattcgtat cagttgagcg tgtattttca gttgtgtccg
     3181 cttttggttt ttccgttttt tcttctggca cactgactgt ttcttctgta actggtgtcg
     3241 caacagcttg cgcagttggt tcatcgtttt tcaatcgttg atcattccag taagacacga
     3301 tttcaataag aagattgtca cggaatcgtt cgaaaatccc gttttctcct gaacgaattc
     3361 tctttaatac agtattgaag ttgtcatcga ttggcacgtt gatccgtgta tcttcatttg
     3421 ttttcccagc taatccgatc gttaagattt gacggttttt gggatcaagc atgacttgta
     3481 acggcaaacc ataacgtcgc aagctctctt cttctagaga acggaataat tgtcctctta
     3541 caccatccaa tgaaggacgg aattgattta ataatttttg tttctgtttt ttcttcatat
     3601 gttctctcct tcgctcatac cctttcgatt ataagaaaaa aacagccaaa tgaaaaggag
     3661 taatgcaaaa aaacttgcgt atacgcaaat tacaacagaa aaatttgcgt attttcccgt
     3721 tttttgaaag aaaaataaaa aatggaacgg attatgtata tatacataat ccgttccatt
     3781 ctttctattt tttcggtatc aaggcaaaaa caggtagttc aggtgaataa atgacttcat
     3841 gttcgtgcca gggtttgacc attagcgaat gatcgaaccg ttttttcagt tcttcgatga
     3901 tttgatcatg tgtccagttt cttgcaggaa aatgttggat tttctctgca tcgatcaaaa
     3961 agacaaaatc ggaatgaaaa gtctgggtaa cttcttccga gagagaattc aagcgttcga
     4021 ttggatccat aaaatcacct ttcgacttaa aattgggtag tatctgggtc ttttgctttg
     4081 ccgactacac catctaactg atcgatttgt ttcatttctt cttctgttaa ttcaaaatca
     4141 aataattcag tattttcttt gattctgctt ggtgtcactg acttaggaag aggaaggaat
     4201 tcgtgttgca gcgaccaacg caaagcaact tgtgcaatcg tcttgtcatg tgcttcagcg
     4261 atttgtttca tttcaggcac atcgaagatt ttaccagtgc ctaatggact atatgcttcg
     4321 aggatcatat catgtttttt tgcatactca actacagttg tctgtaattc gcctggtgca
     4381 aggaaaactt gattgaccat cggcataatt tttgctgttt ttgctagtgt atctagatgg
     4441 tggggtaaga aattgctcac accgattgct ttgattttac ctgcttcata cagttcttca
     4501 aatgctcgcc atgtatctgc atttgcttgt tcccaattat cacgaaaagc aacagggttt
     4561 ggccagtgga tcaaaaacag atctaaataa tctgtttgga gcttcttcaa tgattcttca
     4621 aaagaagaca tcacaagttc atagctgtgg tttgcattcc ataattttgt tgtcaagaat
     4681 atctcttctc taggaattcc actttcctta atcgcttggc cgacgctttc ttcattcttg
     4741 tatccttggg cagtatcgat atggcgataa cctgcagcca gcgcttcttt aacagaggaa
     4801 acagcgacat ccccatcagg tgtttgccat gtgccgaatc ctactaccgg gatttcgtaa
     4861 ccatttgata gacgataagt gcttgttaat gaattcatac tttcagctcc ttttttattc
     4921 gttcaactat aagtgtagcg catttttcga aaaaaagaat ccattttgtt tctactcttg
     4981 aaatttttgt ttaaaagaaa atgattttga ttctggtatt tttgattttt tttccgtaaa
     5041 ctaagacaga agggaatgag aaaatggata tctatttaaa aaaagcaatt ctgcatatta
     5101 ttgacagaga aactggttct ccagtctttt cacaaaaaga gctggatctg acaaaagaat
     5161 atattcgtga ttttcttcaa aagaagatcc aaaaaatctc ttctgctcaa acaaaaactg
     5221 gacaactagc agaagaaagc atgatcgttg aatcacttaa aatcgctcaa gaaaattttg
     5281 tggaagcaag tgaagcaatc gttcagcggt ggttcgatat ctaccaagaa agtgaagaag
     5341 cacctagtgc agatgtattt gttgtcttgt atgaattaga tacagtgatg tacttatctt
     5401 tattgaaagt caattatcgt gaggcttaca ctcactttgt tgaagcagac gaagcaggga
     5461 tcgacaaccg cttgattttg aatcgagcaa ttctaggggc gaaaacacaa aaagcagatg
     5521 aagcattcgc tgtgaatttg actgattgga cctacgaatt aattgaaaaa aaatatgagt
     5581 tttctggcaa aaaagagctt tatttttctg gaagagtgat cgaaagtgtt cctgcacctt
     5641 ctttagaaga aaatgtaaaa gtgatccaaa aagtagccaa gcatcttgga aaaaaatttg
     5701 agacagaaga atttgatatc atggctgatt tgaaagaagc tgtctatgat acgatagaag
     5761 aaaaaggtcg gttggatcat gagatgattg cggaaaaagt cttcaaggaa aacatcacgg
     5821 caaaaatggc ttttaaagaa gaagtacaag agcaaggatt tgtcccagaa gcacctcctg
     5881 taaaagaagt acaagaaatt tctgagaaaa aatttggaaa acaaaaattc aagctatcaa
     5941 acgggatcga actgatcgta ccagtagatg tatatcgcaa cccagatttg attgaatttg
     6001 tgaataatcc ggatggtacg atatccgtga tgatcaaaaa tgtggatgaa gtattgaatc
     6061 gtttataaaa atgactagaa tattaggtgt tcaagtacca gtgatcagtt aaatgaattg
     6121 tgtcaagaga aggatcggaa aagacgaata taacaaaaaa agagcgtgag acaaaagtaa
     6181 agaacacttt tgtctcacgc tctaaacacg tataaacggc ggaagcagaa gcaactcctt
     6241 cttatttctt ggagttaaac gcttctgtcc cagcctcttt ttatctaata aaattttaag
     6301 accatttact aattatcgat tttttctgcc gcatttttag gcacttcaga agcctttatt
     6361 tcttcccagc ttaatacacc tttacgagga ttgactttga gtttaagata cgcattcatc
     6421 tttaatggat gttctctttc ttcgcgaagc gtcacctgtt ttttttcacc atctttatta
     6481 taagccgctt gcttgtaggt ataagtcgtg aatttctctc cgttatctgc ttgggtagct
     6541 gacatttcgc cattcgtcgt gatttttgta taataagctt cgccgccgta aaaataatga
     6601 taagctgcaa aacttccgcc gagaaatatg cctaaaacga caagtacgcc aattaatttt
     6661 ttcatgtact tcacctcttt ccttattatt aacgaaatag aagatttcgt ctattgaaag
     6721 ttgttggcaa cagctgaatt ttaaactttt cctcattttg ttcttattgc ttcaaaagaa
     6781 agttaaggac tatcttgaag tttttctcaa aaaacacatt tttttattta taaaaggtac
     6841 ttttttcgcg tataagacag acgagtgctc ttagttgact ttgaccaata ttgacgtata
     6901 ataagcttag ttcgaatctt acaaaaagta agtcggacgt attctttttg atttagtcaa
     6961 aaaaagacta taataaaaag gtgagagctg aaatttttca gtgatctata ttatttagga
     7021 ggtttgtaaa ttatggcaaa agaacattat gacagaagta aaccacacgt taacattggt
     7081 acgattggac acgttgacca tgggaaaact actttaactg ctgcgatcac tacagtatta
     7141 ggcaaaaaag gcctagcaaa tcctcaagac tatgctagta ttgatgcagc tccagaagaa
     7201 cgtgaacgtg ggattacgat caataccgca cacgtagaat atgaaacaga aaaacgccac
     7261 tacgcgcata ttgatgcacc aggacacgcg gactatgtga aaaacatgat tacaggggca
     7321 gcacaaatgg atggtgcaat cttagttgtt tctgcaactg acggtccgat gcctcaaaca
     7381 cgtgaacaca ttttattgtc acgccaagtt ggtgtaaaat acctgattgt tttcttgaac
     7441 aaagttgatt tagtcgatga tgaagaattg atcgatttgg tagaaatgga agttcgcgag
     7501 ttattgagcg aatatggttt cccaggcgat gacactcctg tgatcaaagg ttccgcatta
     7561 aaagcattgc aaggcgatcc agatgctgaa gctgctatta tggaattgat ggatacagta
     7621 gatgaatata tcccaacacc agaacgtgat acagataaac cattactatt gccagtggaa
     7681 gacgtcttct caattacagg tcgaggaact gttgcctcag gtcgtattga tcgtggtgct
     7741 gttcgtgtcg gtgatgaggt agagatcgta gggatcaaac ctgaaacaca aaaagcagtt
     7801 gtaacaggtg tagaaatgtt ccgtaaaacg ttagattacg gggaagctgg ggataacgta
     7861 ggcgtgttgt tacgggggat ccaacgtgac gatatcgaac gtggacaagt acttgctaaa
     7921 ccaggttcca ttactccaca tacaaaattc aaagcagaag tgtacgtgtt gacaaaagaa
     7981 gaaggtggac gtcatactcc attcttcaac aactatcgtc cacagttcta cttccgcaca
     8041 actgatgtta caggaacaat cacattgcca gaagatacag aaatggtcat gcctggtgac
     8101 aacgtgacga ttgatgttga cttgatccat ccaatcgctg ttgaaaacgg aacgacattc
     8161 tcaattcgtg aaggcggacg gacagtaggt tcaggtatcg ttacagagat cgaagcataa
     8221 gaaacgcgac tcgaatattt tggtaatgaa aaatgtttaa aataaaagag cggtccaaac
     8281 aggatttctg tttggaccgc tctttgttct tcaattgtat aagaagagat tgtagaagca
     8341 tgaactttcg ttttacttca gtctctttta ttcatcatga gagtgttcat ctatcggtat
     8401 gcagttttta atactttctt cgtatccatt ttttcaaacc acttattcta ccttgtgtct
     8461 gctcaactgg cgcattatca ataatcagca aagcaatcat aacatatgca atccaactat
     8521 ctctagaata tagagtataa cgtgagaccc agtttgtagc gtacttgctt ttatattctc
     8581 ttaatccatg gaaagaataa aaatgagaac caaactcgta aaccaagtat gcaatccttt
     8641 cctgtaaaaa actctttctg gaagttccga catttgaaag aggggccatc cctaaattga
     8701 accattggat atgttcttct ttcatatagg caaacaaatg caagaacaag aaatccatac
     8761 tgccagaagg tgctttttta gaatcatatc gcatcagatc aatcgttcct actttattgt
     8821 tcgtgtaagt aggcatgatc gttgcaaaag cgacaatttc ttcttgggta tttttgacaa
     8881 ctgcaatagg cgctctttgt agataatctt cagagaaaaa gcctaaagaa aacccttttt
     8941 cctttcgtga acccaaccaa ttatcagaga tatttttgaa agtactcatt tgctcagtag
     9001 aaaatggtgg ttgtaagaca tcaaatgtaa atccttctcg ttcgatccga ttcaagacag
     9061 cacgagtgcc cttcattttt ttccctgaag ttgtaaaact attcaggtct acataagctt
     9121 cttcccccat cttaatgaaa tcgtagccga attcatgcaa aatcataaca atctcttcgc
     9181 ttgtttcgta gaaaactggt aaatagcata gtcgatctgt ttcttcgata aaagcttcga
     9241 ttgcttctgg aaaatcttct ttcttaccag aaggatcacc cattacaata catttattat
     9301 tgaagcaagc gaattggaga agaacagttg gttcaccgtc tttttcatag gcaaacatcc
     9361 gcttatcttt taagaagatc aattgactat cggagtttcc tccataagtt gtaaggatct
     9421 tcagggcctt ttcttcatta aaggcttcgc caatctgttt cttttctcct tgaaggaaat
     9481 gaacaaatag aacgatcatg aaactaacag cgatgatggc caacaatccc gaaaaccaaa
     9541 tcttttcaga aggaaataag aaaaaggaaa taaaatggtg acgccgatga gggaaatctg
     9601 gcagattgta taccccaata acgatgtaaa gcaaggacag tgcaccaata atgattccat
     9661 cgatcgtacg ccactcccat gaatagatca attgttcccg aaataattcg tttttagaag
     9721 caagaatgat cagaagcaga atagacaaga aaaccaccgg tgtgaaacta aaatcactta
     9781 ataaaacata aagtaaagct agaacaatca agaagattgt aggcaaatat gctcgtttca
     9841 cacgtgctgc gatccctctg cccataatga ttaaaagaaa tcccaatagt atactaggaa
     9901 attggataat aaaatgaaat ttcaatgggt tcaaactatg aagccagcga aactctgtaa
     9961 aagcttgcgg gatagtggca gaaagtacta gcatgattcc agaaaagtat aataagacaa
    10021 ccacgatttt atgcgcaatt tctgttgcta attgtttagg gataccagaa taacgctgat
    10081 caaaagtgga accgatattt ttgaagaaaa agacgattcc aatcaaaaac ggaatgatgt
    10141 agtagaacag gcgatagagc aagatccaca caacgactat ttctcttggc acaccaatag
    10201 cggacaaccc gataatcatc attacatcga aactcccaat ttctcctgga atcatagaca
    10261 cgattcctat cactgaagca gcaatgaata atggaattgt ttgccacaga tcaatccgga
    10321 tttccattaa ataaccaaca gaaaggaaac taaacaggac accggtccat tccaacaatg
    10381 aaactagcaa tagctgtcct tgagttttaa gtgaggtacc accaaggaat cctttctttt
    10441 tgaaagtagt aaataaaaag acgacaggaa aatatagacc gccgccgatc aaccatatcc
    10501 aatattgctt caaaaaagga gcaactggcg tgaagactac aagtaaaaaa gaaagcagac
    10561 tgtaaataga aagtccagcc atcaaaaaca agaaaacttt cgataatgct tggatcacgt
    10621 ttctgctctc tttcttttgt ccatatagtt cagagcgaag ccccacacta acaaacccgc
    10681 cgaaaccggc aatattgttg atcgtattga tcagccagct tgtctcaaac aggtaacgag
    10741 gattctgctt ttgttcaagc atccgattca aaataatatc ataaccaacc ataggtaaca
    10801 cagagataag accaatcaat agcattagtc cgcttttcca tacaggtata gtggcaaacg
    10861 tttctcctaa ttgctggata gatagagttt taccgatgga catcaattca ccgacaataa
    10921 tgacaatgac agaaatcaaa aagattgttt tgaacagtcc taggtggttt ttcagccatt
    10981 gtatggtatt ttttaacaaa taaatcacct tctattccta atagttatgt ttcagaaaga
    11041 aattgaagaa cttctcgatt gaagcgttca ggatcttttc tagctaattc atgtccttgt
    11101 tctttcacaa gcacaaagga agcttttggt atagttttag ctatatacaa agaatgtttt
    11161 agcttgatta catctttttt tcccacgatg atcaaagtgg gggagttgat tttttttaaa
    11221 tcattttctg taagcccgat gtcatgcagc aaaagtttga taactaaaag atttttgcga
    11281 agacttgggc gaaataaaga gagtaaccat acccatgcat aatgaatatt actgatgact
    11341 ctggcagaaa aacgaacgcc tttaacaagc gtgtttccag aatttaaaat caatcgatga
    11401 acttttttag ggaagctgct ggcaaatacc agtgctagat ttgctccatc actaaatcca
    11461 agaaaatctg cctgatcgat tttttccagc aacatgatcg tattcagatc ctcggccatt
    11521 aactgaaaat tcaacataga tgcttcgttt gtcgaacgac catgtcctcg gctatctact
    11581 agatacacgg tatagtagcg ttcgagtaca gggacctgtt ctgaaaaaaa gcggccgctg
    11641 ccgtcattgc catgcagtaa aaagagaggg aagccttgac cgctcttttc atagtaaatt
    11701 tcgctcccat ctggcatttt tgcatatttc ttttcttttt tcacataatc acctactgtg
    11761 taaagtataa cgattatatc agtcattggg caattgtttt tactgaaaaa caacgatcat
    11821 tttcgtaaga tgtcaaaaaa tacaggaaaa ttcatttttt cttaaggcgt acacagaaat
    11881 caaggaagaa atagccaaga agataaagaa atagtaagat aaaaaaagat gtcaaaataa
    11941 ctaggtgatg aaatgaagcg aaaacgatta tctattatcc gtattctttt ttacatgatc
    12001 attctgacgg ttattggtgc ggtgttgttt ttaggaggaa gaacttatcg ttcggtaaaa
    12061 cgagtggaaa gctatcaaat agaaataaca acagctgcaa aaaattatca tatggaaaac
    12121 tacgagaatt tgatcaaggc gataatattg accgaatcaa aaggaaaagg gacagatctc
    12181 atgcagagct cggaaagtct gcatggagaa gctgagatca ttgataatcc agctgacagt
    12241 attgatcaag gtgtcaaata tttggcggaa atgatagtag aagcaaagaa acaaggatgc
    12301 gatttatgga cagctgtcca agcatataat tttgggaaag attatattgc ctatgtaaaa
    12361 aatcatggcg gagaaaacac agtagaatta gcagaagcgt attctaaaga tgtgctgagc
    12421 ccacttttag gaaatgagga agggaaacaa taccgatatt ggcggatcca gtccttgctt
    12481 tacaatggcg gctatctcta tcataatgga ggtaacatgt tttatcctga tattgtcaaa
    12541 atgaatgaaa aaataataga gacctatgaa aaagtcttta agtaaaatag caggaaatgt
    12601 tcaatcatga ataaaattaa atgaaagaag gagtgcgcaa atagtggaaa aaaggcaaaa
    12661 aatggaaaat caagaagtgg ggtacacaac caaagactgg atgttacggt ttgtgaaggg
    12721 aatgtttatc ggttcaggat ttatcttgcc aggagtcagc ggtggtgcat tagcagctgt
    12781 ctttggcatg tatgagcggc tgatttcttt tttagcccac cttacaaaaa atttcaaaga
    12841 aaatgttttg ttttttctgc ctgttggtct aggcggagtg acaggcatct ttctactttc
    12901 ttttttagtc agttttttat taggtgcgta tgaaacaacg atattatggt tttttgtcgg
    12961 atgtatcgct ggaactgttc ctgcgttatg gaaagaagca gggaaaaaag gaagagatac
    13021 ttctgatgtg atcatcatgg ttgttacttt tgttctggct tatttgtttt tattatacgg
    13081 cgctcaatta tttgacgggc aagtcgatca gaattttgga acatggctga ttgccggcgg
    13141 attgattggt ttgggtatga tcgtcccagg attgagccct tctaattttt tggtgtatat
    13201 gggattgtat aaagcgatgg ctgacggatt taaagaagta cgacttgaag tgattgtgcc
    13261 gatcggaatt ggtgggattc tttgtgttct tggattgtca aaaatcatgg attacatttt
    13321 ctcaaaggca tatagcaagc tattccattt cattttaggt gtagtttttg cttcaacgat
    13381 tatgatcatt cctaccgatt acgcgggatt gggagttgct ggggtactag cttgtcctgt
    13441 tctttttata gccggtacag cactaggttg gtggatgagc cgtttggagg aacaatataa
    13501 gtaaagatag attgataata aaaacagcac acgggtgatt caaacaaaaa ggttggcatc
    13561 ttttttgtaa aatcattcgt gtgtttttct ataaatttta taaaaacaag ttgtttttaa
    13621 tcttggaaca cgctagactt aaacacgtga ttatttttga aagttggcgg aaaatggaga
    13681 aaaagaaaat gaatggactt acacagcaag aggtagttca gaaaatggct tctggccagc
    13741 aaaatgacta ccaggaagat gcatcaaaaa gtacaaaaca aatattcagc gataatatat
    13801 tgacgttatt caattttctg aactttggta ttgggatttg tctgttattt gtaggtgcgt
    13861 attccaacat ggcgtattta gcaattattg tcgtcaatat cgttattgga atttatcaag
    13921 aaatacatgc aagaaatctt gtacggaaat tatcgattgt ttcccaatca gaagtactag
    13981 tgatccggga cggtaaagaa caatcgattt ctactaaaga gctggtatta ggagatttgg
    14041 taaaaatcgg agcaggagaa cagataccag ccgatttaca ggttatatct ggacgggcag
    14101 aagcaaatga agctcttttg acaggcgaat ctgatttgat tgtcaaagaa actggagctg
    14161 aattgctttc tggaagcttt ttgacaagcg gttctgtcat ggctgaagtt atccgagtag
    14221 gtgcagataa ttatgctgtc cgcttgacta gcgaggcaaa gactcacaaa gctattcgtt
    14281 ctgaacttgt agattcgatt cgcaaagtat ccaaattcac tagtttcgtg attattcctt
    14341 tggggatcat actatttttg gaagcactgt tcatccgcga tgcttctatc aaaatttctg
    14401 ttattgcatc tgcagcagct ttgttaggca tgcttccaaa gggtttggta ttgctaataa
    14461 gtattgcatt aacgacaggg gtaaccaaac tggcaaaaaa acgaatcctt gttcaagaca
    14521 tgtattcaat tgaaacgctg gcccatgtcg atacattatg cttggataaa acagggacca
    14581 ttactgaagg gaaaatgagt atccagcggg tagaagcact acatccgctg tacgagaaag
    14641 ccatcccaga aattatgggg acgtatctgg cagaaagcag tgataacaac atcactatgc
    14701 gggctatgag agattatttt gagctttcta atcggtatga tgtgacaaac aaagtcgcat
    14761 tttcttctga tcgcaaatgg ggcgcgatgg aatttccaga actgggagtc gtgtacgtag
    14821 gagcgcctga acgtttggtg gaagaagatc ggcttccgga cagtctaaaa acagcccaag
    14881 cgaatggcta tcgcgtactt atgttgggga tcgctccaaa tcagcaattg aacgaagaaa
    14941 aaccagcatt tgttgagccg gttgctctgt ttgaaatcga tgatccaatc cgaaaaaacg
    15001 ctcaagaaac actagcttat cttcatgagg aaggtgtgga tctgaaagtg atttctggag
    15061 acaatccttt tactgtctcc aatatcgcta gacgtgcagg attaccgaat tatgatgcgt
    15121 atgtcgatct ttctcaaatt actgaagaaa tggaagtgcg agaagctgct catcgctata
    15181 cggtttttgg acgagtgagt ccgcagcaaa agaaattgct ggtaaatgaa ttgaaagaaa
    15241 gcggcagaac ggttgcaatg acaggcgacg gtgtgaatga tgttttggcg ttaagagaag
    15301 cagattgcag cattgctatg gcagaaggtg atggagcaac acgtcagatt gcgaatctgg
    15361 tattgttgga ctctgatttt actacattgc cagaagtcct gtttgaagga cgccgagtgg
    15421 tcaacaatgt gacgaaagtc tcaggcatct tttttatcaa aacgatttat tcatttattt
    15481 tatcgattat atgtgccgtt acagcaattg gatttccgtt tatccctatc caaatcacgc
    15541 tgattgattt agcgattgaa gggtatcctt ccttcttttt atcttttgaa caagataaaa
    15601 gaaaaatcac ttaccgttat ttgcctacag cacttattaa tgctttacca aatgccttgc
    15661 ttgtagtagt gaatatcatt gcggtgtatc tacttggaaa aacattcgca tggggaaatg
    15721 ctgaaactac tactttgatg tattacttgc tgattgggat cagttgcatg gcagttgtaa
    15781 aagcttgtta tcccttcaac ccattgcgca tcttcctagc agtaacgacg atcgtaggga
    15841 tatatgtagc tgcaatgctg ttccatggaa ttttggaagt aaacttaggg ttgggagaga
    15901 gcgtaggata cttctttgta ttcatgctcg taaatattgt tcttcgagta ttgtactgga
    15961 aggctgatat tcaaaatcag ttactgaaaa gagtagcaaa ttgatgctta atgagataga
    16021 aatgtgttat acttgaaaaa gcaatgaaat atgatacaat caaacatgta taattgtgtc
    16081 ctttaaaatc gcactgattt cagttagtgc gattttttac cggttattct cctgaaatat
    16141 cttctgttaa acccaaaaga tatcaataga gcagggggtg aaaaaatggc tcaacggatt
    16201 cctcaagagg ttatcgaaac agtacgcagt caaacgaata tcgttgaggt gattggacaa
    16261 tatgtccagt tgaaaaagtc tggtaaaaat tacttggggc tgtgtccttt tcatgaagaa
    16321 cgtacaccgt ctttttctgt tgcagaagac aagcagattt ttcattgctt tggttgtggt
    16381 aaaggcggaa acgtgtttac ttttcttcaa gaactagaag gtctaagttt tccagaagca
    16441 gtggtaaaag tggcagactt cgaacagata ccgttagaag atcaatggcg tcagcgtact
    16501 atagctgtcc aaaatcctga atctgctacg gggaaactga ttgctgctca tgaaaaagca
    16561 gcggaaatct atcatcacat gctattgcat acaaaagctg gacagccagc tttagaatat
    16621 ttgcaaagtc gtgggttgtc tttagaatta attgaagaat tcaacatagg ttttgcacct
    16681 aatgagcgtt cttttcttca gcaagtattc aagaatgaat caatttcaaa tgaattgtta
    16741 gaacgctctg gattgtttgt cacgcatgat gatggccgta tgtctgatcg tttttatcaa
    16801 agagtgatgt ttccacttcg taattctcaa ggccagacga tcggtttttc aggacgctgg
    16861 cttgcacctg aaaaagggca ggaaaaagat cagcccaaat acttgaatag tccagaaaca
    16921 gaactgttca ataaaagaca agttttattt aatcttgata aagcaagaag cgatatccgg
    16981 aaaaacggag aaattttgtt gttcgaaggg tttatggatg tgattgctgc atggcaggct
    17041 ggtatcaaaa ctggattagc ttctatgggg acaagtctaa cagctcaaca gatccaacaa
    17101 atggaaaagc tgacgaaaga attggtcttt tgctatgacg gagacaacgc aggttttgaa
    17161 gcaaccaatc gagggattga attgcttcgg caaaacagtc gattagcact ttctgtcgta
    17221 gtcgttccag aaaagcttga tcctgatgaa tatctccgta agtatggaga agcatctttc
    17281 caagaattag tggctcatgg gcgcgaaaca gtctttactt ttaaatcacg ttatttaaaa
    17341 caagggaaaa atttagataa tgaaaaagac aagatcgaat acctcgaaga attactagtt
    17401 gaacttagcc gagttgtttc accaatcgaa caagatatgt atctatctca actgtcaaca
    17461 gagtttcaga tcggcagaga gacgatacaa aaacaactgc gcgatcttcg aaggacaaat
    17521 cagcaaaatc gtcaagaacc tcaggaaagt caacacactc aggttacgag acaagaaact
    17581 gcacggaaaa agagaccttt gacgcaagta gaaaaggcag agcagattct attatatcgt
    17641 gcatttaaag aagtttctgt ccgtaatatt ttaaaagaac gagaatttca gtttattcat
    17701 gatgcatatg cagaagttta ttttttattc gatgcatatg tctcacaaca ttatgaattc
    17761 aaccttgcag agtttttaga ctttttgcaa gatgaaaatt taaggcggtt ggtggtggaa
    17821 atcgaatatt taccggtggc agaagaaagt tcgccacgag aaatccaaga cttgctagat
    17881 gtgatcagca aatctggctt agctgatgaa ataacattaa aaaaacaaat gcagcaagaa
    17941 gccagacgaa ctggaaacaa acagcttgag cttgaattga cgattgaaat catcaattta
    18001 acgaaacagt taaaacaagc caaatagcta ctcaaggggg gccttctttt atggcaaatg
    18061 gaacagataa aaaaacgtat gaagcagcag tagcagcttt catcaaagaa aacaaaccca
    18121 aacgacaagt tgtatatgat gatttatcca atcagcttgc tacaccattc actttgaatg
    18181 cagatgaaat ggacaaattg atccaaaaga ttgaagacgc aggtatcagt gtggtggatg
    18241 aaaatggtga tccatcaatt cacagcttga agagtgctga gaaaaaagct gaacaagcaa
    18301 aaacagaaga tctttctgcg ccaaccggtg taaaaatcaa tgacccggtt cgtatgtatc
    18361 tgaaagaaat tggccgtgtc tcccttttaa ctgcggaaga agaagtagcg ttagcattga
    18421 aaatcgaaga aggcgaccaa gaagcgaaac agcgtctggc agaagcaaac cttcgtttag
    18481 tagtaagtat cgctaaacgt tatgtaggac gaggcatgca gttccttgac ttgatccaag
    18541 aaggaaacat gggactgatg aaggcagttg aaaaatttga ctaccgcaaa ggatttaagt
    18601 tttcaaccta tgctacatgg tggattcgtc aagccatcac tcgagcaatc gctgaccaag
    18661 cacgtacgat ccgtattcca gttcatatgg ttgaaacaat taataaattg atacgtatcc
    18721 aacgtcaatt gctgcaagac cttggaagag aacctacgcc agaagaaatc ggtgcggaaa
    18781 tggatcttcc aacagaaaaa gtccgagaaa tcttgaaaat cgcgcaagaa cctgtttccc
    18841 ttgaaacgcc aatcggtgaa gaagatgact ctcacttagg tgatttcata gaagaccagg
    18901 aagcaacaag tccagcagaa cacgcagctt atgagttact aaaagaacaa ttggaagatg
    18961 tactagatac attgactgat cgggaagaga atgtccttcg cttacgtttt ggtttagatg
    19021 atggccggac gagaacattg gaagaagtag ggaaagtgtt tggtgttact cgggaacgta
    19081 ttcgtcagat cgaggctaaa gcattaagaa aattgcgcca tccttctcgt tcaaaacaat
    19141 taaaagattt cttagaataa gcgtggacta ttgaccagaa gagaaatcag taaaactgtt
    19201 tggtttattt taaaagaaaa aaagcttgag actacgcagt ctcaagcttt tttttctata
    19261 ggaaggaaat tcattcatta tttttaagta aatcctaaaa ataagctatt ggcgtgacgt
    19321 atagaatatg atagattaaa tggtagcgta aacctagtaa aggagccgat cgctaagtga
    19381 tgaaaaaatg tccaaattgc ggatcgaaaa aaatggagca gaatactatc tgtccagact
    19441 gcggtcatca aataactgca gaagatcagc aaataaaaga atcaattgaa gaaacaaata
    19501 cagatgcagc tatgcaggat aaatcaactg aagatgcagt ctttcctgat acagaattaa
    19561 acgatccaat cgaatggtcg gaattgaaag atttacctct agaatctgta atggaattat
    19621 tcgaaaaagc agaaccagaa gacgaagaac cacctgctca cgatcaagta actaatatag
    19681 agaaaaatga acagaagaaa gcaactgttc atgagacttc ggaagaatca ggaaagaatc
    19741 aagaagaaac gcttgaatca aaacaaaaaa gaagagtagc tgaactgaaa gaaatcgtcg
    19801 ataatgagga agaaaattcg atactatccg cttatatcaa agcacatcgt gaagatacaa
    19861 aagaagagca cgcgaaagag ctgctcaaaa tgatcagtga aaaaattgca caggaaaaca
    19921 aagtagagcc agaaaaggaa caagaaactg aaaaagactc tgatagagaa aacgccacag
    19981 gtaaagaaac agtaaaaata aaagacgtaa aaacggatat cacagaaaaa actgaagtat
    20041 ttactgaaaa acaattagaa aaggaaaaaa cgaataaact gccggaagca gagaaaaaag
    20101 aaatactcga aaacacagac aaaaagtcaa cagagcccga tgaaataaat agtgaatccg
    20161 atgctgaaaa tcaatctgta agcaaagagg gtactgatct tgaagcaaaa atagaaaaag
    20221 aagagaacca gcctaagctg tttgaagcag aagcgaaatc aataacaatc gtgccagata
    20281 ctgaaaaaac acatcaagaa tcaaacttag aaaaaacaga tccagataaa gcgcaaaaga
    20341 aaaaatcaaa aaaagtacct tatctcgttt tagcagcagt acttctactc ggtggaggaa
    20401 gctgggctta ttatgaccat catcaaaaag tagaagccga agtagcagca gaagcaaaaa
    20461 gacagcaaca aatggaagaa cttcatgaga aacttgctgc cttttataca gatgatcacc
    20521 atcaatttat tcgtgcagat atgattcatc aagatttatc aaaactaaaa aatgatttat
    20581 ccagtcttaa gaatgaaaaa ggatattcag agttagaaac aacttaccaa gatatccaat
    20641 ctaagatccg agatatccaa aaagtgaatg agtggttcat agcacctgcc atcgtcgatg
    20701 atcatctagc agatgacatc aagttgaaag cagataaaga gatccaagca atcgaaacgg
    20761 ataacacaga ttttggaaaa ttgattcaac aagcacaaac agaagctaaa aatcaatatg
    20821 ctgaattgca aacagctaaa gaaaaaacag ctatagtctt taaagacgga aaagtagtgg
    20881 attcagcaac acgcgaccaa tacaagacgg caaaagaagc agtagaaaaa gtgaaaaata
    20941 cagatctatc tgctcagttg aatgaacaat tgaaacaagt agataagatg ctcactgata
    21001 aagagaaaaa agaagaagag gaaaagaaaa aagcagaaga agcgaaaaaa gcagctgaag
    21061 aacaagcaaa acaagccgct caagcagcag ctgcagctca agccgctcaa caagctgcgg
    21121 tcgcacaagc agcacagcaa gaagcggcat cctcgacccc ttcctcttca aactcagcga
    21181 atcagccaat caaatctgcc agagcaagtg atattgccga tgcatctaat ccagcatgga
    21241 cgtgggcacc aggtgtccaa agcaaagtga ttgctacatg tatccaacgt ggatatatcg
    21301 ttgaaggagg ttacagatta gaaaaagcca gaatcgaaaa tggggaaggc tattataatc
    21361 tatatgccac ttcaacaaaa tctgcattga tgaaaggcat tggagaaagt gctttgccat
    21421 tttacatcgt aaccatcaac tgtaaaactg gatggttcgg aggaaatggg agcaattaat
    21481 tttaggcaaa tgaaagaggc tgtgagcctg ccgtttaaca ccgtttattc gaaaaagggg
    21541 agtatgacac aactgttgtc atactccttt tttcaccttt ccaaaccaag gctcagctat
    21601 tcaagtagat aacattatgt tatgatagca aagaaatgta ttaagaaaac ctttcactat
    21661 agagggagaa aaaaatgaac gatttattag caactatatt tacaggtatt attattgatg
    21721 aaaatgaaaa aaactacttt gtccaaaaaa acggacaaac ctttggctta agcaaatcag
    21781 aaggtgaaca caaaatcggt gaagcagttg aaggattcgg ttaccaaaat caaaaacatg
    21841 aaaatcggat cactacacaa attcctaaaa gccgtatcgg tcattacggt tttggaatcg
    21901 ttactgctac acgaaaagat ttaggtgcgt ttgtcgatat cggtcttcca gataaagact
    21961 ttgtcgtatc tcttgatgaa ttgccgacaa tgacagagct atggcctaaa aaaggggatc
    22021 gcttgatgat ttcccttaga gttgatgcaa aagaccgtat ttggggcagt ttagcagatg
    22081 aaaaaatatt caaatcttta agcaaatatg gaacagaaga aatgaaaaac aaagatgtga
    22141 taggaacagc ataccgcttg aaattaacag gtacgtacgt tttaacggaa gatttctatc
    22201 ttgggtttat ccatccttct gaacgatata atgaacctcg tctaggcgag cagataaaag
    22261 gtcgagtgat tggtgtccga ccagacggtg tactgaatct ttcattgaag ccaagagcat
    22321 atgaagctat atcagatgat gcacaaatga ttttaaccat tttagaacgt tctgcagatc
    22381 agcaaatcaa ctttacagat aaatcggatc cagaagaaat catgaaagct tttggtatca
    22441 gcaaaggagc atttaagcgc gcattaggta atcttttgaa acaaggattg attacacaag
    22501 aaaacggtgt gacaaaacta gtcaaaaaat ctaattgaga atcccttgca tgtttttctt
    22561 aactagctta taataatttt aattaacata gtgttatatc tttttttatt tgtaattatt
    22621 ataaattgtt ggggttgagt aaatggtcat gaatgctatt tcggcgatga aaaaaacaaa
    22681 acagcagcta catgaagcgg ggtttaagct gacaccgcaa agagaagcta ctctgcttgt
    22741 gcttttggaa aatgagaaag agcatttatc tgcagaagaa atcttctttt tagtgaaaaa
    22801 aaagagtccg gaaattggac ttgctactgt ttatcgaacc cttgaaatct tgacagaatt
    22861 gaaaattgtc gataaagtaa gttttaatga tggattagcc cgttatgatt tgagaaaaga
    22921 aggcgccaaa catttccatc atcatttact atgcttgaac tgcggcacga tcgaggaagt
    22981 agaagaggat cttttacttg aagtggagca agtagtagaa gaacgttatc attttttagt
    23041 aaaagatcat cggctaacgt tccatggaat ctgtcaggaa tgctatgaaa aagaaaaaag
    23101 aaaccagtcc gtctgagtgt ctagacggct ttttctttgc tcagattatg gaaaaagact
    23161 atcagaatga agcggtatct gatatgatag agaggcatga gggggattat tatgaaagag
    23221 caaatcaacg attatctcca ctacttgaat attgaacggg gattgtccgc caatacacga
    23281 caaagctatg aacgtgattt ggaacagtac ttgcattttc tacaggagca gaaaattgct
    23341 tcatggcagg atgtcgatcg ctttttagtc atccgttttc tggagaagtt gcatgaagaa
    23401 aaaaaagcga cagcaactgt tactcggatg atctcaagtc tcagaagatt ccatcagttt
    23461 ttacggcaag agcgtatcac tgatcatgat ccgatgcaac atatcgatac gccgaagaaa
    23521 gcacagaaat taccaagtac attgactctg acagaagtag aaaagctgat tgaagcacct
    23581 gatacgacaa aaacgttagg gataagagat cgtgcaatct tggaagtcat gtatgctact
    23641 gggatgcgcg tcagtgaatt gattggattg aaattgggag atcttcatct ttctcttgga
    23701 ctggtacaga cagttggaaa aggagataaa gagcggatca ttcctttagg tgattatgcg
    23761 atccaatggc tggaacgcta cttagacgaa gcacgtccat tacttgtaaa ggacgcatct
    23821 gaaatgcatg tatttgtcaa taatcatggg aaaggtcttt ctcggcaagg aatctggaaa
    23881 aatctgaagc agttagtacg agaggctggg atttacaaag aagtaacacc acatacgctg
    23941 cggcatagct ttgccacaca tctgctagaa aatggagctg atttgcggac agtacaggaa
    24001 ttgttaggtc acgcggatat ctctacgact cagatttata cacatatcac gaagaaaaga
    24061 atgacggatg tttataagca gcattttcca agggcttagt cataggaagg tgagaagatg
    24121 ttaacacatt accggaaaga aaaccgtaaa attgctatgg gactattgag tttccataag
    24181 aaactgacag gtaaaacttc tttgttgaag gagattgata cgtacgaatc tgaagacgat
    24241 tatgaacttt ttttctttac gccagaaggt tcaaccaaca ttcaagggat tattggtatt
    24301 tactgggcaa cgaacgatca gctgatcatc catgacattt ctttgaatcc gtcttatcgc
    24361 ggtgagaata tgggctttca aatgttagat gaattacagg aaaagtaccc ggatgtctcc
    24421 atccgtgcaa ctgaaatcac agagccttac attggaaaat ggctagcaaa gaaaaagaag
    24481 aaagagtgaa tgagttgacg gagatcaata ttaaattaga tgtattcgag ggtcctctcg
    24541 atctgctgct tcatctgatt cagcaaatgg aaatcgatat atatgatata ccgatcgcta
    24601 cgatcacgga gcaatatatg aattatatcc atacaatgaa aacactcgag ctagctgttg
    24661 caggagaata cttagtgatg gctgctacat tgatggcaat caaaagcaag acattgcttc
    24721 ctgtccaaga attcgtcaca gacgatgaag aattatggga agaagatcct cgagaagaat
    24781 tggtcactca gcttttagaa taccgtaaat ataaatatgc agctgaaaga ctgacagaaa
    24841 aagcagagga acgaagtctt tattacacaa aagaacctat gaacatcgat gggttagcgg
    24901 atgctgaaaa gccgttgaag cgaggacaag tcaaaaaaat cgatttgatc cgtgccatgc
    24961 agaaaatctt agaacgtaag aaattttctc aaaaagtgga aaaaacgatc acgcccgatg
    25021 acacaacgat cgaagaacga atggtattta tcgaagagcg tataaaaaga aatgcgcatg
    25081 gctgtacttt cgattctttt tttgagtcac cttctaaaag tgaagttgtc actactttta
    25141 tggctttgct agaattgatg aaaaaagggc agatcattgc gcaacaaaaa gaaaactatg
    25201 aatcaattat gctttatcca gcagtaggag ataccgaaca tgacgaaatt aagtgaactt
    25261 gaagcccttc tttttattgt tggcgaggaa gggatcagta atgaagaatt aagcggactg
    25321 ttaaatctca gcgaagcaga agtcacaagt ttagtgaaag aattaaaaga atcttacact
    25381 caaaactcgc actcagcttt gcatattttt gaaacggaaa gccattatgt attaacgact
    25441 aaaaaagagc tggctccctt acttaagcga tatgcgcaag ggacatcaaa cacattatct
    25501 caagccgccg tcgaaacctt agcaatcatc gcttataaac agccaatcac aagagctgaa
    25561 atcgagcaga ttcgaggagt tcaggtttca ggagcggtac agcgtctagc tgcccataaa
    25621 ctgattgaag aaaaaggtag agtagaagga ccaggtcggc cgatattata tggaacaact
    25681 ggctacttct tagattattt tggtttgaaa tcattagaag aactgcctga tacacaagaa
    25741 atggaaattt cacttgaaga agacgtgtca ccagatctat tctttgatgg aatgaataaa
    25801 ggagaataat tgtaatggag agattgcaga aagtaattgc ccacgctggc atcacttctc
    25861 gtcgaaaagc agaagaattc atccttgcag gacgtgtaaa agtaaacgga caagttgtaa
    25921 gggaattagg gataaaagtt gggaaacatg acactgtgga agtggatgaa gtcccaattt
    25981 atcaagaaga atacggttac tatttattgt acaaacctaa aggagttatt tctgctgttg
    26041 cagatgacaa aggaagaaaa gttgttacgg atcttttgcc gatggtaaaa gaacgtatct
    26101 atcctgtagg tcgactggat tacgatactt cggggatctt gctactgaca aatgatggag
    26161 attttgctca gcgcctgaca catccaaaac atgaagtgga taaagtttac gttgcaaagg
    26221 taaaagggat cgctacaaaa tcgatgcttg cacctttgac aaaaggaata aagatcgaag
    26281 gacgaaaaac atctccagct aaattccaaa ttttatcagt ggatcctaag acaaaccaca
    26341 gtatcgtgga attgacgatc cacgaaggac gtaatcatca agtgaaaaat atgcttcaag
    26401 cagttggtct tcctgtgcaa aaactaaaac gtgaaaaata cggagatctg actttacaag
    26461 gcctacgtcc tggggattac cgtgaactga acaaaaaaga agtcagcagt ttgctgaacc
    26521 actcaaaatg aacacttact ttttataagt gttagatgtt gcgttttttg aatagatatg
    26581 tataatgaat atgtaaacaa aaattatata aggttcgtct tcaggggcag ggtgaaattc
    26641 ccgaccggtg gttatagtcc acgacctatt ttgcaaaaaa atagctgaat cggtgaaatt
    26701 ccgataccga cagtatagtc tggataaaga agatagagct tatttgacga cgcttgatca
    26761 aataactcta actctatttt ccctggaaaa tagagttttt tcatttggag agaaacgtca
    26821 aaaagttcgc tgaagaggag tcctaacagg aggatttcaa atgaagaaca cccgtgtaca
    26881 gaaaatggtt gcagtagcga tgtttgctgc gatcgcatta gttttacagt attttgcttt
    26941 tccgatcatg ccggctttta gttttttgaa gatcgatttt agtgatatct cggtattgat
    27001 cagcatgttc ttattcggtc cagcggccgg agttgcaaca gcgttcttgc gttcagtatt
    27061 acatctgctg actacaggtt tttctccgga taatttggta ggagacactg ctagtttctt
    27121 atcaacaacg atctttacat tcccgattta ttatttcttt agtgtaaaga aacagcataa
    27181 aggaagaaac aaatttttag gtgtcattac aggaaccatc gctctaacta tttttatgag
    27241 tatcgcaaat tatttcgtta ttacgcctct ttacttaatg tttttagggc tgaacgcaac
    27301 acagatgctg ggcatgtctt tagcaaacta tgtactgatt gggatcgttc ctttcaactt
    27361 gatcaaagga ttcatcgtga gtgctgtctt tttagtgctg catgcgcaac ttcttccatg
    27421 gttaagtcga aaacaacatc agttcgaaca acgtcataca gcagtcaaat aaatatcaaa
    27481 aagatcaaga aatttcttgg tctttttttt tggaaaaaaa tacaagacat gcaataatgt
    27541 aaacgtttta tttgtttgtt ttgagtattt ttttgattta tgcataaaaa tcaatcaatt
    27601 ctttgcaaat gtgaaattct tctcctttta aaagacgaaa atgtttgttt ataaaaaaaa
    27661 ggaaacgcta caatgaaaaa gaagaaagct ttaaaaacct gaaaaaagag gagggaatag
    27721 ggaaaaacga actttttgaa caaaagtttt acaaaatgcg tgttattatt tttgttctga
    27781 tactcttttt gataaaataa cattagagcc aaaattgttg tctctaacgg aaaagaaagg
    27841 aagaagaaga tggaacaaac aaaaaagaaa aaatttcaaa tgccttcagc gtatacggtc
    27901 ttatttatta ttattgcagt aatcgctgta cttacttggt ttataccagc tgggcactat
    27961 agtgtagacg atgcaggcaa catcgtcgct ggatcatatg aacgagtaca acaaaatcct
    28021 caagggctgt gggatatttt catggcgcca atcaatggga tgctaggtgt accagcgggg
    28081 gagctaacta aagaaacacc tgctgcaatc ccaatctctt tcttcatttt ggttgttggt
    28141 ggatttttag gtattatcaa caaaacaggg gcactagatg ccgggattgc ttcagttgtg
    28201 aagaaattca aaggaaaaga aaaaatgctt attccagtat tgatgctgtt atttgcatta
    28261 ggcggctcta cttacggaat ggcagaagaa acgattccat tctatgcttt actgatccca
    28321 gtcatgatgg ctgtaggctt tgatacagta gtagctgtag caatcgtatt agtagggtct
    28381 caagtaggct gtctagcttc aacggtaaat ccttttgcaa caggcgtagc ttcacaagct
    28441 gttgggattt cgatgggtga aggtattggt cttcgattct tgatgttcgt tattttgtta
    28501 gctatttcta ttgtatatgt gtatcgttat gcatcaaaga tcgaaaaaga tccaacaaaa
    28561 tcattagtat acaaccaacg taaagaagat atgaagcatt tcgatattga agcaatcggt
    28621 cgtcaagaag taatcacgaa aaaacaaaaa catgttaatg tattgttctt tattactttt
    28681 ggtatcatga tcatcagttt gattccttgg acaaccttga atgcgaattt cacgattttt
    28741 gaatcattga caaactggtt aacaaacctt ccggtactag gtacggttct aggtaaaagc
    28801 atgcttccat taggtgactg gtacttccca gaaattacta tgttattctt agtaatgtcc
    28861 atcgtagtag caatcactta tggcatgaaa gagtctgaat ttgtctctga atttttagct
    28921 ggtgcttctg atttgatcgg tgtagcaatc gtagtagctg ttgctcgtgg tatccaagtg
    28981 gttatgaaca atggattaat cacagacacc atcttacatt ggggcgaaca aggattaagt
    29041 tcattatctt caagtgtatt catcattatt acatttattt tctatatccc tatgtcattc
    29101 ttgattcctt caacttccgg cttagctgct gcaacaatgg gaatcatggg acctatgggt
    29161 gaatttgccg gcgtcggtaa ggatttagta atcactgctt atcaatctgc atctggttta
    29221 gtaaacttaa ttacaccaac atctgctatc gtaatgggtg ctgtagcaat tgctcgtttc
    29281 gatgtttcag tgtggtggaa atttaccggt aaattaattg cgatattatt tgtagccatc
    29341 tgtgtgatcc taggtgtagc agcaatgttc taaacctaga caaatacagg tacaaggtct
    29401 atcataagaa tgaagaaacc gataaacggc tatcgataag cacgtggata agtcaatagc
    29461 tccattcagt gagtgttttt tctttcatca tttgttaaga acattctgct tgctgatgga
    29521 gcaggcttaa aacgtcatta tttgagaaga agaggttgtg tcggaggaat ttgacatgac
    29581 cctttttaac atattaggag gataatatca tgaaaaaatt tgtgacagaa caacatcatg
    29641 aacaagcatt agaatcattg agcgaattga tccgaattcc ttccgtacta gatgaagcag
    29701 attcaggaca aggacatccc ttcggtaaaa aagtgattga agctttggat aaagtattgg
    29761 aaatcagtga aaagctagga tttagaacat ttaaagatcc agaaggctat tacggttatt
    29821 cagagattgg ctctggagat gaattattcg gtatcttgtg tcatatggac gttgttccag
    29881 caggggacga aaataattgg gaaacaaaac cattcgatcc aactataaaa gacggctggt
    29941 tagttggtcg cggatcccaa gatgacaaag gtccttctat tgcggcaatg tatgccgtca
    30001 aagctttgat tgatgctggc gtggaattca agacacgtat tcgttttatc tttggtacag
    30061 atgaagaaaa tttatggcgt tgtttagaaa aatataacga aaaagaagaa ggaattacgc
    30121 aaggatttgc gccagatgct gaatttcctt taatttatgc agaaaaaggc ttattgcaag
    30181 cttacttgac aggaccagga acgaacgagt tttctgtaaa agctggagga gcgttgaatg
    30241 ttgttcctga tgcagctcct tactctggag aaaagctttc tgaagtaaaa gaagcattga
    30301 aaaaacacga attcgatttc gaagaacaag gtgaaggcat cgtcgttctt ggtaaaagta
    30361 tccacgcgaa agatgcagca caaggagtga atgctatttc tcgtctggca attgctcttt
    30421 cagaagtatt tgattttggc ccaatcaatt tcttaggaaa attagttcaa gaaaatgcaa
    30481 ctggtgaagc tgtcgtgggc aaaacagaag atgaacaatc cggcgagcta acgatgaact
    30541 ttgcaagttt ggaaatcaca ccagaacaaa caaaaatcgg tgtagatatg agaatccctg
    30601 ttacattcaa gaaagatgat ttagtagcta aattaactaa aacagcagaa aaatatgggt
    30661 tgacttatga agaatttgac ttccttgatt cattatacgt gccactagac agtgagttag
    30721 tgaaaaatct attggggaca tatcgcgata ttactggaga catgactgaa ccgtttgtat
    30781 caggcggcgc tacttttgct cgtacgatga accagtgtgt ggcattcggt gcgatgttcc
    30841 ctgatactcc tgactttatg caccaggcga atgaacgatg ggaattaagt agtatgtata
    30901 aagcaatgga aatttatgca gaagctgtgt atcgtttatg tgctaaataa a
//
LOCUS       DAXQKX010000029        29571 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.029, whole genome shotgun sequence.
ACCESSION   DAXQKX010000029 DAXQKX010000000
VERSION     DAXQKX010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29571
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.029"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(47..1342)
                     /gene="purB"
                     /locus_tag="ACF3MF_001478"
     CDS             complement(47..1342)
                     /gene="purB"
                     /locus_tag="ACF3MF_001478"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HFE3927476.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(1355..2479)
                     /gene="purK"
                     /locus_tag="ACF3MF_001479"
     CDS             complement(1355..2479)
                     /gene="purK"
                     /locus_tag="ACF3MF_001479"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HFE3927477.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            complement(2472..2960)
                     /gene="purE"
                     /locus_tag="ACF3MF_001480"
     CDS             complement(2472..2960)
                     /gene="purE"
                     /locus_tag="ACF3MF_001480"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HFE3927478.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            complement(3376..4683)
                     /locus_tag="ACF3MF_001481"
     CDS             complement(3376..4683)
                     /locus_tag="ACF3MF_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HFE3927479.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            complement(4686..5267)
                     /locus_tag="ACF3MF_001482"
     CDS             complement(4686..5267)
                     /locus_tag="ACF3MF_001482"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HFE3927480.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     regulatory      complement(5383..5480)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(5839..7131)
                     /locus_tag="ACF3MF_001483"
     CDS             complement(5839..7131)
                     /locus_tag="ACF3MF_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFE3927481.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     gene            complement(7128..7751)
                     /locus_tag="ACF3MF_001484"
     CDS             complement(7128..7751)
                     /locus_tag="ACF3MF_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927482.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            complement(7754..8590)
                     /locus_tag="ACF3MF_001485"
     CDS             complement(7754..8590)
                     /locus_tag="ACF3MF_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFE3927483.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            complement(8607..9494)
                     /locus_tag="ACF3MF_001486"
     CDS             complement(8607..9494)
                     /locus_tag="ACF3MF_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFE3927484.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            complement(9510..10793)
                     /locus_tag="ACF3MF_001487"
     CDS             complement(9510..10793)
                     /locus_tag="ACF3MF_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFE3927485.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            complement(11476..12159)
                     /locus_tag="ACF3MF_001488"
     CDS             complement(11476..12159)
                     /locus_tag="ACF3MF_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HFE3927486.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            complement(12177..12794)
                     /locus_tag="ACF3MF_001489"
     CDS             complement(12177..12794)
                     /locus_tag="ACF3MF_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFE3927487.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            complement(12804..13628)
                     /locus_tag="ACF3MF_001490"
     CDS             complement(12804..13628)
                     /locus_tag="ACF3MF_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HFE3927488.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            complement(13621..14181)
                     /locus_tag="ACF3MF_001491"
     CDS             complement(13621..14181)
                     /locus_tag="ACF3MF_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927489.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            14354..15310
                     /locus_tag="ACF3MF_001492"
     CDS             14354..15310
                     /locus_tag="ACF3MF_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFE3927490.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            complement(15615..16571)
                     /locus_tag="ACF3MF_001493"
     CDS             complement(15615..16571)
                     /locus_tag="ACF3MF_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HFE3927491.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            16675..17277
                     /locus_tag="ACF3MF_001494"
     CDS             16675..17277
                     /locus_tag="ACF3MF_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFE3927492.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            complement(17365..18864)
                     /locus_tag="ACF3MF_001495"
     CDS             complement(17365..18864)
                     /locus_tag="ACF3MF_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HFE3927493.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(18880..19404)
                     /locus_tag="ACF3MF_001496"
     CDS             complement(18880..19404)
                     /locus_tag="ACF3MF_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HFE3927494.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            19702..20451
                     /locus_tag="ACF3MF_001497"
     CDS             19702..20451
                     /locus_tag="ACF3MF_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFE3927495.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            20442..21227
                     /locus_tag="ACF3MF_001498"
     CDS             20442..21227
                     /locus_tag="ACF3MF_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFE3927496.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            21196..21912
                     /locus_tag="ACF3MF_001499"
     CDS             21196..21912
                     /locus_tag="ACF3MF_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFE3927497.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(22014..23033)
                     /locus_tag="ACF3MF_001500"
     CDS             complement(22014..23033)
                     /locus_tag="ACF3MF_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacid dehydrogenase"
                     /protein_id="HFE3927498.1"
                     /translation="MRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIVSAKDH
                     DAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVPSYSPN
                     AIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRIGLTEA
                     VLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQMINEG
                     FLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSFKPWET
                     IPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPK
                     ARQLR"
     gene            complement(23052..24053)
                     /locus_tag="ACF3MF_001501"
     CDS             complement(23052..24053)
                     /locus_tag="ACF3MF_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HFE3927499.1"
                     /translation="MTSTVFIILLGFVCRKKGIFSESVGKILSKVVLTVALPALAFRA
                     FMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYKGDKQTTLRVLTIFGSTTFF
                     GTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGLKMEAKNIKAMFVNPIIIAT
                     FAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPWLFQPMDYLAGLSSPLAWLA
                     IGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILAVLTATNILPVNFEALATIV
                     IMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVLTPVWIVVLQMIHGIGLFS"
     gene            complement(24331..25479)
                     /gene="nagA"
                     /locus_tag="ACF3MF_001502"
     CDS             complement(24331..25479)
                     /gene="nagA"
                     /locus_tag="ACF3MF_001502"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HFE3927500.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(25555..26391)
                     /locus_tag="ACF3MF_001503"
     CDS             complement(25555..26391)
                     /locus_tag="ACF3MF_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3927501.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(26575..27792)
                     /locus_tag="ACF3MF_001504"
     CDS             complement(26575..27792)
                     /locus_tag="ACF3MF_001504"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFE3927502.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(27941..28102)
                     /locus_tag="ACF3MF_001505"
     CDS             complement(27941..28102)
                     /locus_tag="ACF3MF_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927503.1"
                     /translation="MEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGIAMDWAA
                     NLWNDYHDN"
     gene            28175..28258
                     /locus_tag="ACF3MF_001506"
     tRNA            28175..28258
                     /locus_tag="ACF3MF_001506"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:28209..28211,aa:Leu,seq:gag)
     gene            complement(28498..>29571)
                     /locus_tag="ACF3MF_001507"
     CDS             complement(28498..>29571)
                     /locus_tag="ACF3MF_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927504.1"
                     /translation="YVFEKINVKNLLLVCSIYCLIPLTVMGETGWRATTLNYQWPVAF
                     SLLTFYPFFQLLRGEEINRKIYWVSIPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGR
                     YNYKLSVFSIISLAELIFSLTTPGNALRAAHEINKWFPEYKNFNFLNKLDLGISSFGK
                     PFFLDMNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNTMGQSFTYVN
                     GNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGIYLSFDNKKT
                     SIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKELMKSMSVQK
                     NEFMQFGLTVLGICTFIITVINR"
BASE COUNT         8843 a         6304 c         5064 g         9360 t
ORIGIN      
        1 tatttttgct attctatttt aattgaattt tgcaactcac tcttctttat tccaaaccta
       61 ctcgtttgaa tatcacgtca acgtttttca aatgatgatg ataatcaaag gcatcgtcta
      121 tttcttcttt agataatacc gatgtgatgg ttggatcttc ttctaacagc gggcggaact
      181 gcacttggtt gtcccaagcg tacgcagttt ttggctgaac aagatcataa gcttcttctc
      241 ttgtcattcc cttatcgatc aatttcagca taacgcgctg gctataaatc aaaccaaatg
      301 ttgcagacat attccgcttc atgttttcag gaaagaccgt tagattttta acgatattgc
      361 caaaacgatt taacatgtaa ttcaataaaa tcgtggtatc aggcaagatg attcgttctg
      421 ctgaagaatg agaaatatct ctttcatgcc ataatgtgac attttcatag gcagtgacca
      481 tgtgtccgcg caccactctg gctagaccag ccatattttc tgaaccgatc ggattccttt
      541 tgtgcggcat agcagaagaa cctttttgac ctttcgcaaa aaattcttct acttcacgtg
      601 tttcggattt ttgcaatccg cgtatctctg ttgcaaaacg ttcaatactt gtagcaataa
      661 gcgccatcgc tgagaaatat tcagcatgta gatcccgagg gagaacttga gtagagattt
      721 cttgtggacg gatccccaat tgtttacata catactcttc aataaatggc gggatatttg
      781 cgaacgttcc cactgctcct gagatttttc ctgcttctac tccttttgcc gcatgttcaa
      841 atcgttcgat gttccgtttc atttctgaat accatgtggc aagtttcaat ccaaaagtag
      901 ttggttcagc atggacaccg tgtgtccgac ccatcatcac tgtatatttg tgttcttttg
      961 ctttttcgcc aatgatttcc gtaaaacgtt tcaagtcttc ccgtaaaata tcatttgctt
     1021 gcttgatgag atagccataa gcagtatcta cgacatccgt acttgttaga ccataatgga
     1081 cccattttct ttcttctccc aatgtttcag aaaccgctcg tgtaaacgca acgacatcat
     1141 ggcgtgttaa tttttcgatt tccaagatcc gatcgatatc aaatgatgca tgctcacgaa
     1201 tttttttcac atcttcttgc gggatttcac caagttctgc ccaagcttca tctgctaaaa
     1261 tctcgacttc gagccacgca cggtatttgt tctcttccgt ccagatattc cccatttcag
     1321 ggcgtgtata acgttctaac atgttttttc tcctctaatc ccaaatattc gtttgtttga
     1381 tttcttccag cgtttgctgg atgtcttctg tcaagatagt gatatgtccc atcttgcgac
     1441 ctttttttgc ttgttttttt ccatagaaat ggaattgcca gtctggctta ttctcaatca
     1501 agcgatagct ttccagcagt tgttctccca aaacattgac cattactgca ttgcttatca
     1561 aacgtacttt ttctcctaat ggccaaccac aaatacctcg aatatgggca tcgaactgac
     1621 tcatagaaca agcttcaata gaataatgtc cagaattgtg aggacgagga gctaattcat
     1681 tcacatatag cccgcctgtt tttgttaaaa acatttctac ccctaaaaca cctgaaaggc
     1741 tcactgcttc tgcaatcaca cgggcaatac gctcagcctc ctcgatcaca tcctgatcaa
     1801 tcgcggctgg agcaatcgtt tcatgaagaa tattgttgtg gtggatgttt tccacgaccg
     1861 gaaaagtcgt gaaatctcct tgaccatttc ctgccaccat gatcgaaatc tctttttcaa
     1921 acgggatcca tgcttctaaa acacaggttc cttctcttaa aaggtccatg gcaggagcta
     1981 gatccgcccg acttttcaaa acatactgcc ccttgccatc atagccgcct cgagtggttt
     2041 tcaaaacaca aggatagccg atcccgtcaa tcgcatcttg gatatccgtc ggactgacga
     2101 tcgttgcata aggagcaatc acgatgttat tcgtttccaa aaaagatttt tctaacaggc
     2161 ggtcttgcgt aatcgcaagc aagtctgtcc cttgaggaat aaatgacatg ggtaaaatcg
     2221 catttaacgc ctctacactg acgttttcga attcataggt aatgacatct gttcttctgg
     2281 caagctcttt cagcgcaaag gtgtcatcat agacactttc aatgtgccaa tctgcaactt
     2341 gtgcggctgg acaatcgctc acaggatcca gcacacctac tttaaagccc atttcttttg
     2401 cactaatcgc catcatacga cctaattgac cgccaccgac gatcccgatc gttgaaccag
     2461 gcaacaaagg tttaaccaag ttgatcacta ctttctataa cagttttagc caacattgaa
     2521 cgtctttcag ccaatttagc ctccaattct aaatcataca tggaaagcat ctgtatcgca
     2581 agtagtccag cattaattgc tcccgctttt ccgattgctg tagtagctac aggtactcct
     2641 ccaggcattt ggacaatcga aagaagcgaa tccaaaccat ttaatgttcg tgattggacc
     2701 ggtacaccga taaccggcaa agttgttttt gatgcgacca tacccggcag atgcgcggct
     2761 ccccctgctc ctgcaataat gattttgatt cctttttttc gagcgttttg tgcatattca
     2821 aacatcaaat ctggggttcg atgagcagaa acgacctttt tttcataaga cacaccgaat
     2881 tcatccaata tttgacatgc ttctttcatt gtttcccaat ctgaagtact ccccataatc
     2941 acagagattt ttgctgtcat tgtttttcct cccagttttt ctacattcat attttaacaa
     3001 tcactttttt tgatgtcaaa gaaatttcga atgttaacaa agaaaaacat tttattgttc
     3061 gtgtttatta aagataaaaa aaaggaatgt gacaaaagtt aggtcacatt cctttttatg
     3121 gataaacggt gttctcctgc caactcctcg gtcacaagga acaatattca acaaacatga
     3181 gaagcttttt tttgaaattg ttccttgtga ctcggagatg aacggcaggc tcacgacctc
     3241 ttccttcaac ggtgttcaat cagctgaccc tcggtattag ctcaaacaaa cggcaaaata
     3301 cgaggaacta tttttccgtt tgtttctcta acaatcaggt caaaacgctg atttcacaac
     3361 ctttcttttg ctctattact tcttgaaggc ttcttccaat atttcttcat cttttttcaa
     3421 tccattaaag atcaaattca atatgatagc cgtaatgcta ctcattacga tgccatttcc
     3481 agtgaacatt tgcaatgttt gcggcatttg actgaataat gtcggcgtaa cattgaaacc
     3541 cagcccaaat ccaacagaaa cagcaacaat caatagattt ttatcattgc tgaaatcaac
     3601 ttccaacagc atacggattc cttggactgc caccatcccg aacatgacta acattcctcc
     3661 accaagtacc ggctcaggga tgatttgtgc taacgcaccg attttaggga ataatcctaa
     3721 aacaatcaag aagaatgcag agaaatagat gggttttctt gttttgattc ccgaaagttg
     3781 aaccaatccg acattttgag aaaagccagt ataagggaat gtattgaaaa taccgcctaa
     3841 gataacggca agtccttctg cacgatatcc ctttttcaat tcttcttctc caacattttt
     3901 cccagtaatg tcaccaagtg caaaatatac acctgttgat tctaccatgc tgaccatgga
     3961 aatgatgatc attagtaaaa tcgaccatac gtcgaaagtt ggtttaccaa aataaaaggg
     4021 ttgtggaaca tggaacaacg gcgcatctcc aatcgcgctc agatcaatca ttcccatgaa
     4081 agcagctaag atgcttcctc cgactaaacc aatcaatacc gcgattgaac gaatgaaccc
     4141 ttttgccagc atttgcacgc ctacaattag gagaatcgtc acaaatgcaa gtagcagatt
     4201 tgttttgtca ccaaaatcag ctgctgttgc attacctcca cccattttct cgattgctac
     4261 aggaatcaaa gtcaaaccaa taacggtgat aaccgttcct gttactatag gagggaatag
     4321 ttttttaatt ttagaaaaga caccagaaac taacacaaca aagatcccag aagcgataat
     4381 agatccgtag atagctccta ctccttcatt ggttccgatc aagatcagtg gagctactgc
     4441 ttggatcgca catcctaaaa cgacaggcaa gccaattccg aaaaatcggt taactgtcaa
     4501 ttgcaataat gtcgctaatc cacacataaa gatatcaatt gaaatcaaat aagtcatctg
     4561 ttcttgatta aagcctagtc ctgtaccgat caaaagaggc accgctactg ctcctgcata
     4621 catcgctagc agatgctgca gccctaaaac cgcagctttt ccattttgtg tttctttttc
     4681 cacgattatg cgtcctcctc aagaaactca acttgtccat tcgtcaagga agcaatacgc
     4741 gcaagagaaa cgactctcaa tcccatttct tcaagtaact gacgtccatc ttggaaagac
     4801 ttttcgatga cgatcccgat tccttctact tgcgctccag cttgctggca taattcgatc
     4861 aatccttttg ccgcttgtcc gtttgccaag aaatcgtcga taatcaatac tttgtcttct
     4921 gaagataaaa atttacgaga aatagaaatc gtacttgtca cttgtttcgt aaaagaataa
     4981 acagaagctg tcaataattc ttcatccatc gtcaaacttt ttgcttttct agcgaagatc
     5041 attggaacat ctaattctct tgcagcaaat aaagctggtg cgatcccaga agcttcaatg
     5101 gtcacaactt tcgtgattcc ttgttcttta aatacttctg caaaccgttt tcccatttgt
     5161 tccatcaata cagggtctac ttggtgagtg acgaagctgt cgacttttaa tacgccctcg
     5221 cctaatatac gtccgtcttt ttgaatacgt tcaactaatt ctttcacttt atttgctcct
     5281 ttatcattta ttaataccga aataaccgct tttgtgcaaa aacctactat gtttctgtta
     5341 aagaaaaaca ccctccactt tatcataaga aaagaagggt gaaatagcca atcttttact
     5401 tatagtccag catttacggt actggctaga aactgtcatc catattatga cgatatataa
     5461 gtaggtatgt aaaactaata atagtgtaaa ttcattttct tgcaactgtt ttgcacgtga
     5521 aggcagtttg ccatatttga ataaaaaatg ttgtttcaaa tattgaaaac agtctaacac
     5581 tactttctga aactgacaac gtggtttact tatttttttg taaaatctaa tgatttttaa
     5641 tgcattattc ctttttgttc gggtttaaat agttattttt attttctcct atctaaaaaa
     5701 gcagcccaca taaaaagaag gcatgacaaa aagcatgtca tagccccttt ttccgaataa
     5761 atagtgttca aaagacagcc tatcggcaat aaggcaagat tttataaact acgggaagta
     5821 atttccgtaa atctattctt attcttttaa gctgacaagc tcgtcaatca ctactgcttt
     5881 tcctgaagca atagaatgat ttgctgcgat tcctgtcaaa atcgacaaaa taccatctac
     5941 gtgagttgct gcccgattcc acggatcttc ttctttttct tcaccaaata gatcatctaa
     6001 taaacgcgga tctcctccgc catgtccgcc cgcttcttgt tcgacgatta cctcatatgg
     6061 ctcaccgaac atcggataga catggatgga ctgaagaacg gctgctcctt catccttttt
     6121 atctccacct gcattgatgt aagacttttc gatcactttc atttcgatcc gtcctttgct
     6181 gccattgaaa gaaacattga atccttccca cggcatatac gcgtttagcg aatacgtcaa
     6241 aatcgcacca gtttcatatt tgaccgttac gcctagtgta tcttcaatag agatatcatc
     6301 ggaaaataca ctgcggtcac gaatatatcc actgtctttt tctgcttcta aatacatttc
     6361 tcgcaattcc tcattggctg acaggtctat agcaaatgga tcagctttag ctagttcgct
     6421 tccatagcat cgactgtaaa atatttctac tccgcgtttc tccgcattat gcatcccata
     6481 aaagtttaat ccaccgaatg caaatacctt ttggggacgg ctgttcaacc aaaaattcac
     6541 tagatcaaaa tgatgggtag atttatgaac aagaagcccg ccgctattgt gcttatttcg
     6601 atgccatctt ctgaaataat ctgccccgtg ttgcgtattt aacagccatt cgaagtggat
     6661 agaaaacaca tcaccaatca catcactttc tatcagttcc tttatcttcg tgtgatacgg
     6721 tgcataacga taattaaaag tgactcgcag gcttcttccc gtctgttttt ggaccgttat
     6781 tatttcttga gctttttcct catcgatagt cagaggtttt tcgcaaataa catcatatcc
     6841 ttttttcatt gcacgaatga tataatcatg atgcgttcga tctactgacg taataatgac
     6901 ttcagccggc cgtacgtcat ccagtagttg ctcaaattgt gatggcatac atgtctttac
     6961 ttttttctgt ccatacttgt tcacaagtat ccgatttgca taatccatcc ttgtttgaga
     7021 tacatcacaa aaaccgacta gttcacaagt ttgatgatac gtagaggcaa ttgcctcata
     7081 aaaaaaacgc gctctcccac caagtccgac ttgtacatat tttttcttca tttaaagtca
     7141 ttctcctttt cttttaagca aaatactgtg acaaatggca gccctggata cagtaatgca
     7201 gtgagtaaaa aatcatgctg tatacaccag aacagtccat acaaaaggca taaataccac
     7261 agaaacccct tgacgttttt tgacaacagc cagatattcc ttttgatcaa ataaacaaga
     7321 ctatctgctt tatcttcttt gcagatatca attagcgtac taaaaaaact atgggataca
     7381 aaaagcaaca gacacaatag aaaaggaatc agataccaag ctccaatctt tcccactaat
     7441 aaataccaat caactgcaaa aataatgaca aacagctgaa acaacgtaat gatgaaacac
     7501 atccgtttga tttttccttt cctccaacat accttttttt ctgccaagta atggacagat
     7561 agataataag aaggatacat catcaaaaaa taaatcagat agacaacacg agcagacagc
     7621 actaatccta aagtgaacaa acatcctaga actaaagcga aaagagcatt actgataaga
     7681 ctggttaaaa aaatccgaca gacatagtag ttgagcttgt aaagaaacat ctcttctatt
     7741 ggctttttca tattcagccc ttcagaccgc ttgtactgat cccctggaca agatatttat
     7801 tgaagaataa gaaaatcaga aaaaccggta gcagcgacaa cgtagacatc gcaaacatac
     7861 tcgcgtaagt cgtactagat ccagcgtctg caaataattt gatggcaatc gataccgtgt
     7921 aagatctcgg cttgtttaaa taaatcaatg gtcccatgaa gtcgtcccat ttccaataaa
     7981 actggatgat gatcgtcgtg atgatcgaag gtttcagcaa aggaaaaata attttggtaa
     8041 agacactata cttgctgcat ccgtcaataa tcgctgattc atctaactct ttggggatgc
     8101 tgaccatgaa ttgcatgatc tggtaaatga aaaatgcttg tccaaaaaaa tgtggtaaaa
     8161 tcagcggcac atacgtccca accaaattca gccgattgta aataataaac tgcggaatca
     8221 aaatcacttg tgcaggaatc atcatcgtta ctaacatgac gacgaaccag aatctttttc
     8281 ctttgaaatc gattctcgat aatgcgtaag caatacaagt cgagctcaga actgtcccta
     8341 tcgtcgaaac tgcagagatg acaaacgaat tcctaaagaa agtaaaaaat gaaattccag
     8401 caaaccccgc ccatcctttt gcgtaatttt cccattgaaa agtctctgga atcaaattca
     8461 gcgaaccact cataatctct tgatccgttt taaaagaacc tgcgatcatc cataagaccg
     8521 gataaatcat gactagacct aatagcaaaa taaaaccgta ttgaaaccat ttcgttactg
     8581 tattattcat ttcttcctcc tctcattcac acaacgaccc atttttttga tgatttgaaa
     8641 atcagaaagg tgacagctcc cataatcaac agcatgatcc acgaaatagc actagcatac
     8701 cccatagaat taaaagaaaa agcttggtta tacacataaa gagcataaaa gttcgtggca
     8761 tcattcggac caccttgggt aatgataaat gcctgcgtaa aagtcataaa cgccgcgatt
     8821 gtctgcataa ccaagttata caaaatgatc ggcgaaagaa gaggtaacgt gatcttgtaa
     8881 aacgtctgcc atttgttcgc tccatcgatc tctgccgctt cataatacga gcctgggatc
     8941 tctttgatac ctgcagcaaa gatgatcatt gccgaaccga attgccaagc agacatcaaa
     9001 acaagaggga tcatgaccag tttttgatcg ctaaaccagg aaagcgcagg tgcgcctaat
     9061 cgttccagga aaatattcac taacccgttt ttagaaaaca actcccgcca aactagagcg
     9121 atagaaatac tgccaccgat caaactaggc acataataca aagaacgaaa gaaagtcgtt
     9181 cctttgatat tcctcgttaa aagataagca atcaatagac caaagatcag tttcacaggt
     9241 acagatgcaa atacatagag aaaagtgact cggatggagt tcaaaaaacg ggcatcactc
     9301 agcatcttta tataattatc caagccgatc catgagactg gatttcccaa acgataatcg
     9361 gtgaacgaat aataaagtga caagatcatc ggtatcactg ttatcaatag aaatcctagg
     9421 atgaatggag aagcaaatac gtaaccgacc acattgtctt gatccaagaa ccgttttagt
     9481 ttttcttttt tcatgccttc ctcctgctgc tatcctagaa tgtttgacgc aaactcataa
     9541 agactctctg ctgcttcttc tgctgttact tcttcataaa tgactttttc aactaaaaga
     9601 ttgtattggt cttgaatttc cggattcaaa gcactatcaa agacattcac ttcgccgttg
     9661 tccatatcgg aaatcatttc taaataatca aatgtcgctt gcaaagttgc atcatctgca
     9721 cgagcgagct gttctcgaat attcgacatg attggtacac cacgttctcc ttttaaaatt
     9781 tcattggctt cttcactgtt ttgaaagaaa tcaataaact tagcagcttc ttctttatgg
     9841 gctgagcttt ttgccatact cagcatttgc gaagaacgta aagggatacc agattctcca
     9901 tctgcttttc tgcgaggtgg attaatcaac tgaatctcca tatcttcagg agcccctgac
     9961 aatatttctg tcaactggtt acttgataga aacaccattg ccgcttctct atccctaacc
    10021 gcctgaaaag acagatccgt cgtacttgca gctccaccac ctggttctgg atgggcccct
    10081 ttgtctacca gatttttacg cagctggaaa aaatctgtta gatagtctgg attttcaaat
    10141 cccaagctgt tagatagatc ttcccgatta taaaaattca atcctttctc aacttgtggt
    10201 atttgaataa tacagccagc tataaaatct tcgaatcttg aaatagcata gattcctaat
    10261 tcttcagtga tttgatagct gatttgttca aattcatccc atgtccaatt tgaagctggt
    10321 tcagggatat ttaattgttc aaatatattt ttattgtaag caatcgcaaa cgaattcacc
    10381 ccgttagaca gtccaactaa ttgcccgtcg taagtcgtcg ttgctaaata ggattcatct
    10441 gcattagaaa tatcaattat cccttgctcc acatattcat ctaatggttc aatctgattg
    10501 atgtattgag gaaattgatt gttcagttgg aaaatgtccc agatatcatc tgatgctgct
    10561 agtgtaccta attttgtgta atatccttca taatcataaa attcataatc gatcgtcaca
    10621 tggggatttt tttcttcata aagctcgatt acttttactg ttgcatcgtg tcggacttgc
    10681 gaaccccacc aagccatgtt cagcgtgatt tttttgtcat cttcttgccc acaagccgtc
    10741 aagaagaata acataacact taaagctaag atgattctca ttcttttctt cattctctgc
    10801 acctctactt ccattgttat ttttcaatat actgtatttt tatacagaac atatttatta
    10861 aacgatcttt ttcaagggga ataaaaacca agacttgcct tatcgttctg cctaggatga
    10921 acaactcaat actttcaaga aaaattagat agtgctgatt cttctttcat cgctaaaaac
    10981 acttcttgct tcaatgatgg gaggataatt acgcaaagaa aaaaggatat cagacaactg
    11041 cccaatatcc ttgacatagc taaataagca tgcttcttcg tgtgcgctct tccctaaaaa
    11101 acagaaaaat aactagtaat tctgtatgaa attaggtaca atatacacgt cgatgcacaa
    11161 gcattgacta tggcaacttg attggtcagt tcccgctgac ttttcaagcc ccgacaattt
    11221 agctgctact aaattgtcgg gtgccttttt tagtttttat tcgtttttca ttctatagaa
    11281 agcgcttcaa taaatcaaga catttttttg ttagaatgct aataataaca aaaggtttta
    11341 actcttctta tgtacattac aggtaaaaaa acaaaaaaat ttctcttttt tttgaattct
    11401 gaacaaatag tactggagta caaaagacga ggaagagcca ctatctgctc ttcctcgtct
    11461 tttgattctc acctgttatt catgattctt tttctcagtt tcccgatatt tttccatttt
    11521 acgactaaaa agctctccgc tacttggtgg cgtatatgtg atggcatttg ctcctgcttg
    11581 aatggtctca gcaatacttt cttccgttgg accacctgtc gcaatgatag gaagttcagg
    11641 atatttttta cgaaaatggc gtactgcttc tgcagtttct ttacctgcac tgatattgat
    11701 aatcgaaata ccagctgcta acttttcatc tatttctgta tatttcgacg ttaccgtact
    11761 gataactgga atatcaacta ctcgacaaac ttcttttact gtctctaaag gcgtaggacc
    11821 gttcaaaacg acccctaacg aaccttgcgc ttctgcgaac atgctcatgt aggaagaacg
    11881 agcaccttgt gtcaaaccac cacctacacc ggagaaaact ggaatgtcag ctgcctcaat
    11941 aatgctttta gtaatcgctg gatgaggtgt aaaaggatac acagcaatta ctgcattcgc
    12001 atttgtatta cgtatgatcg caatatccgt agtaaagatg atcgaacgga tcaattttcc
    12061 aaatatcttg atcccgcttg cttctaaaat gatttccggt actcttacga tatcttttct
    12121 caattccgtc atgatttctg gcgtaaattg ttctgccatc agccacttct cctttgctat
    12181 ctccggtcat actgattcaa ttgatacgtc tcgatgacct ggatgatttt ttgcgcataa
    12241 ccggggtctg tcgcataacc tgcatcttgc aatgcttgtg cggcttcctg atagttggtg
    12301 gccgtaatca ctttttcata cagcgcagga ttccaatcta ctccttggac gaacagttgt
    12361 gtatggtcat ccatggactg ttcccatgaa tcatacactt tgaagtctcc ttggatagtt
    12421 atccattctt cgttaacaaa ttcctttgtt tccaggctta ctttcttctg atccccataa
    12481 gccttgatcc cgaaaagatt attgtatttg ctagccaagg tactttttcc ccaatttgat
    12541 tctaatatag cttgtcctaa aatgatacta ggaagcactc cataaccatc ttgtagttct
    12601 tgggcatgcg gaacaagccg ttcaataaat tgctgatggg attgcgcttc attttcttgc
    12661 tgattatcag taaaaggaga agacagattc ttcaaggaaa aaacaaaggc taagagtatc
    12721 actgctacac cggcaaccac tgctggccaa cggatattct tgcgcttttg ctttttccac
    12781 ttttttttcg ccatgatcaa ttcctacttt tcatttaatt cattcagata ttcttctagc
    12841 gtcaattggt gtttggtgat atactcagcg ttttctttac cgacataacg taagtgccaa
    12901 ggttcatatg tgatcttagt tatatcttcg tgtccttttg gataacgaac gataaatcca
    12961 tactgcgcag cattatctgc gatccattta gctccaggct gatctccgta acttgcatcc
    13021 aatacagtag aaggataact gttgtaccag ttttgatcga cgacatcgac tgccagacct
    13081 gtgtggtgtt cgctgtatcc tggctccgta atcgtttctt tagtaatctt tgtcgcctcc
    13141 tcttctgata caccttgacg actcatcaca tcttggacat tttgttcgaa aacttgttgt
    13201 tgggatgata cagaccggta agctgagacc atcactaatg gaaatccagc tgcttcagca
    13261 gccttggcaa atgcttcata ttctggagca atgcgtttgt cgatcaagta tccgttactt
    13321 aatgatgcca attgagtaga ctcatcaatt tctttttcta atttgtgatc tggaccaacc
    13381 aaaactagct tccaatcgtc tgttttaaca tctggcaatt gtttggacgt acgatctttt
    13441 gtttctttgt cctttacctt gctgctggtt gtttgactgt tcttttcttt actagcagtt
    13501 gttttggtgc ttgttcgttc gactgcttga ttgccggctt gaacatgcga atcatcatcg
    13561 ctaaaaataa catagcccat tgctgcgatc ataatcacaa ctgctccaaa tcctaaaaat
    13621 ttattcactt gaaaaatcct ttcgttgttc ttcacgttcc ccattcgcct catgaacgta
    13681 agtttcttcc agattttcat tcacccaatc gagaagttcg attttttctc cttcgatctg
    13741 tttttgaaca tctgctggca gacgaaaatt caaaatatca tcatagcccc attcatcata
    13801 ttgaatactt actttcaagt caaggtatct accagcctgc tgattatttt tcaaagggat
    13861 cagctcgact tttgctgctt tgctgctaag ccatttttgc gcgatgcgtg ttttgatttg
    13921 cttgtactct gcaacggcaa cgtttcgttt ttcgggaaaa ataatcgttt gacgcaaaat
    13981 cttttgcgtt agcatccatt cataatcagt gaaaagattt tttactttct gcatcgcttc
    14041 agatggcaga tttttctcgc catctttcca tttttgccat tgttctggac tgatcagcaa
    14101 gtattcatct aaaaaatttt tttcagtttc aaactgttct aataatacac tcataataag
    14161 atcaatatat acttgatgca cgtttatccc ctccttttaa ctattctact taagttttga
    14221 tcaaaaagca cctcttaaat cgctgctttc atttttttaa tgtttcaagt cctctcctct
    14281 ttattcttcg tgatttttgt tataataata gacagacaag aaactcaatc caactatgaa
    14341 ggagcgtttt cagatgaaaa aatatcaatg gggaatcgtt ggtcttggta ccatcgcaca
    14401 tgagtttgcc gaaagcttca atcaagagac gagcgaacta acagcagttg cttccagaac
    14461 ttcagaaaaa gcggaaaact tcgctcaccg ttacaatatt ccaaaagctt acggaagcta
    14521 tcaagaaatg ttagacgatg ctgaaatcga catcgtgtac attgctgtac caaatagaca
    14581 gcatatcgac catatcttgg cagcattgga agcaggcaaa cacgttctat gtgaaaaagc
    14641 catcacgatg aataaaaaag aactggctga cgctatgcgc ttagcagaag aaaagaattt
    14701 gatcttagca gaagcgatga caatcttcaa catgccactt tatcagcagt tacgctcaat
    14761 aatggataca ggaaaactgg gggctttaaa aatgatccaa gcacctttcg gcagttacaa
    14821 agaaccagac cctaaaaacc ggttcttcaa tccagaatta gctggaggag ctctgttgga
    14881 tatcggtacg tatgctgtat ctttcgctcg tttctttttg agctctcaac ctgaagtagt
    14941 tgcctctaca atggttcctt ttgaaacagg cgtggacgaa caatccgtca ctatcttgcg
    15001 taacaaagaa aatgaacttg ctgctgtcag cttgactttt caggcaaaaa tgccaaaagt
    15061 cggtatcgtt gcctttgaga acggttatgt gacgattgct gattacccgc gtgctgatcg
    15121 tgcggagatc ttatttacag atggtacaaa ggaattcatc gaaagcggga atacatctga
    15181 agcaatgaat tacgaaataa agaatatggt acacatgatt gaaggtgact tgcccaatcg
    15241 ctctctcttc ttgacaaaag atgtcatcga aatcttggat caaatgcaag ttctatggaa
    15301 aaatatgtaa ttttaaaagg ttgtgaaaaa gctgttctgc atcaagtaat aagaacagcc
    15361 aaacaaaaat agctcctcct atttttcgtt tggctggact tattaccgca gaggaaagct
    15421 tttgaacacc gtttaagaaa gaggttgtga gcctaccgtt cagctccgag tcacaaggag
    15481 caatttcaaa aaacagcttc tcatgtttgt tgaatattgt gacttgtgac cgaggagttg
    15541 acaggagaac accgtttaaa gaagaggttg tgaaatcagc tttttgacct gaatattagc
    15601 tgaattcaca acctctattt ttggattttt tgttgggaga attctgcctt gatttcaata
    15661 aaacttttaa aagactgcaa aaactggaac aattctgctc gatcctcgaa ttcagggcga
    15721 ctagtcggca gaggcatttg ccgatacaat acataaactt cttcaatacg tgttaaaatt
    15781 tgtctgccat catttgactc tgaaaatgtt tctgcagtat aaatcaataa accatagata
    15841 tgttttccat aataagctgg ttgctggatt ctctctagat tttccagcat gtctttaatc
    15901 acattggcct gtgctcttct catagagaag taagtttcgt agtatagcgg ctgtctgagc
    15961 cagtagtttt cttgatgttc tctggcatct tcttggcttt cgcgaatgaa tgtcagtaaa
    16021 tgttcgcatt tgatctgcac atcttcttta ttttctgata aaagaaattc tgccatttgt
    16081 ctcaaaatat ttcgaaattc tttttcgatc tgtatttggt tttccttcag ctgcttcgta
    16141 cgatctggca tgtaaacatt tgcaagcaaa gcaaatacta atccaatcgc cattaatccc
    16201 gcttcattgc cgatcagctg ccaagacatg ttttcctcca ctaaataatg agtgaccaaa
    16261 accgaattta ctactatccc ttcggttaat ttgaagcgag aggcaagcgg gatgaacagg
    16321 aataaaaaaa gactgaagcc aaaaatagta tacccaacag caaaaaaact gaacagtgct
    16381 gttgccgtag ctaatataaa ggctgcgatt cgattcatgc ccgtacgcaa tgtagagcgc
    16441 ttggtatttc ctacacttaa taatgcaatg atccctgcag ctggccaata caacagcgat
    16501 aagctacccg ctgtgaccat cgaaaagaag acactgatca ctgttttgac tgttcgcatt
    16561 cctatacgca tttacttccc ccttttttat tttaattata cttgaataat gaaaaactag
    16621 ctatcagaca aaagtttagg tatgatagta aaaagaccaa aaaggagaat ctctatgcaa
    16681 tttggccgtt ttcgactagg tatgcgtacg atcaaaagtg ccttagctgt ttttttatgt
    16741 atcttgtttt ttcatttgac tcaacgagga atcccgatga ttgctgcatt atctgctgtt
    16801 ttttctttgc gtcaggactt gactacaacc gtttcttttg gaaagtctag gatcatcggc
    16861 aatacattag gtggtacatt agctatcatt tatttttttg tcaaaagcta ttttcacaat
    16921 gattttttgg tagaattgat cttgcttcct attctagtta ttattgtgat cgtcgtgtca
    16981 gatggtatta acaataattc cggtatcatt tccgcaatag ctacgttgtt gctgattgcg
    17041 ttgagcatcc ctcaaggcga atccgctttg tatgctatcc aacgtgtact agatactttt
    17101 atagggacat tcattgcaat cggtatcaat ttctttcttc gtcctcctga aacagaaaag
    17161 aaggaagaac tatcagaaga tttggtcgaa ctccaaaaga aagaacgatt gctaagaaca
    17221 aatttacaag agatagaagc taagatccaa aaacaaaaga aaaatagcga ggactaattt
    17281 tcttttgcaa taaaataaaa aaatggagag aagaacttta aaaagtcttc ctccattttt
    17341 gattgaacgg tgaagtgtac tactttattc ttccttcatc gagttttgtt ctgcctcttt
    17401 tggcgcttca tacatattta cttggctagt agtcccacgt gtcgacaaat tctctacgat
    17461 ttccttcaag tcaagtcctg ttgtcgcttt tagtgtttct tgagtagaag aaagcaaatt
    17521 tgtggcataa tttgtcactc ggttcgctcc actggtttct cctgaactgc ttcctgtatc
    17581 gacaacagag attttttcga tatttcctag cggctgtgct gcttcgcgca tcaattgcgg
    17641 tagcatatcg ataaccatac tcaagacagc tgcttcgcca tattccttga aggcattggc
    17701 gatcttttgt tttgcttcgg cttctgcttt tccttttgct agtgctgctt cggcttctgc
    17761 ttgtccagct aaacgtgtct tattggcttc cgcttctgcc agtgcttcca cacggaatcg
    17821 ttctgcttcg gcttcagtca cttctttgac tttttgagct tgtgcttctt gttctttagc
    17881 gtaccgatcg gcatctgctt ttttcttcac ttccgaatca tattgctttt cacgacgtgt
    17941 gatttctttt tcttccagtt cgatttgttt ttggcgttct acgattttaa tctgcatttc
    18001 ctgttcgatt acttgttgtt gtgctcgggc actttctaaa ttgtaggctt ggtctgcttt
    18061 tgctttagca acatcttgtt cttgtttgta ggttgctaat ttcagttctt tttcttttaa
    18121 tgattctgcg atctctgttt gtcgctgtaa ttcagctgct tgtgattctt tttctgcttg
    18181 agcttttttg atacgcgttt cttttagagc ttccgcttct gctatatctg catctctttt
    18241 gacttgggcg attcttggtt tccctaaaga gtcaagataa ccgtttttgt ctctgacctc
    18301 tttgatagtg aaagaaacga tgatcaaccc catttttgca aggtctacag aagcgacttc
    18361 ttgtacgctt tgactgaact tatcgcgatt ttgatagatt tcttctacag tcatagaacc
    18421 aagaatcgag cgcaagtgtc cttctaatac ttctcttgct tcattttcca gttcttctct
    18481 tgtcttgcct aaaaactgtt ctgctgctgt agcaatctct tctacagatg aaccgatttt
    18541 gatgatcgaa gtaccatcac acatcaccgg tacgccttgt tccgtataca cttcaggggt
    18601 ggagacgtcc aatttactcg ataatagact gatccgattc gaacgttgaa aaactggcaa
    18661 gacgaatgcg ccacctccac gcacaatttt gattttgtta ttgctttcat caatgtgcac
    18721 atttttgctt cctaaataac ttccactgat gatcaacgct tcatccggtt ttgctgtctg
    18781 gtacttcgct acaaagacga tcagcaacat cagtaaaatc aaagctgcga ttgcgatcgc
    18841 gataaaaaca actggtattt ccatttaaca cacgctcctt taagctttta tcatgctttc
    18901 ataaggcatg acataacaga ttctttcctt gatctcaatg atcaatactt tcgttccccg
    18961 ctcagctgtc tgttcttggg ggctgtaaaa acaagctgga cgactaatgg aaccggtaac
    19021 acttttcaac tgaatttctc ccatacctcg tacagggatc ggtgtgatca caacagctac
    19081 ttgtccttcc agagtttttt cagaagacga catcgttgat tcggcatgtt tcatcggcat
    19141 caatatatag aaattaagca aaaataccaa cactatcgat atgcctccac tagcaataaa
    19201 taaaaataaa gatgattgat ctgttaaacg ctcacctaga aaaccaaata agcttgtgaa
    19261 agttaaccaa gggataataa gcatcggatc aagcgggcca tcaaaatcga atacatctcc
    19321 aaaaataatc aataggactg ccaatcctgc acaaatcagc aatgtatacc aataaatcgt
    19381 ctcaagtgcg attcccccta tcatatacac gcctccttcc atttctacgt ctatcatacc
    19441 aatgtttgaa aattctgtat agcttctttt accgactcag tggtgttttt tataggaagg
    19501 ttgtgtttat cgttgacaat ttgttaaatt tttgttttca tgttaaaatt ttcacaataa
    19561 attctttcga ggtagcctat gtttcctttt tttaagaaaa aaccattaaa gctccagaac
    19621 acgatcatcc ttgtcgtttg tttctccaca ttcgtttctt tgattgtttc tgccatattg
    19681 atcaggaatt ttattctttc gatgaaccga tctagtgtgt cagataaaat ctctagcatt
    19741 gctaaaatcg ttgccaatga taaactcatc caaaaaaagc tgcagactgg tgacccgaca
    19801 catgcgattc aaggaataac aaatgaaatc atgattgcat cgaatttaga ttttatcgtt
    19861 gtcatggacc ctgaaggcat tcgatattct cacgcagacc caagttacat cggtcttcct
    19921 ttctcaagtc atgaagatgt gaaaaaagtg attggaggac aagaattttt ctctgaaaaa
    19981 gaaggaatgt tagggttcgg cttccgctat ttcgtcccta tttattatga tcaagagatt
    20041 attggtgcag tttgtgttgg cttaacaaac aacacgattg acaatcaagt caaagatgga
    20101 caaaaaatga ttgttttttc attgattatt ggacttagcg taggcatcat aggcgccgtt
    20161 tttcttgccc aaaaaatgaa aaaagtactg cttggacttg aaccacaaga aatagcagaa
    20221 cagttaagtg aaaaaacgat tatcgaaaat gaagtagatg aaggaatctt agccatctct
    20281 tctgataaaa ctatcctctt gatcaataca cctgcaaaaa acattttcta ccaaacagag
    20341 cagctattgg atttcgaagt aggaaaaaaa tcagtgataa tctatatgac gttttgttta
    20401 aagagacgat tgagcatcaa acgaccgttc ggactcaatc catgtattta aatgggatag
    20461 aaactatttc tagcgttaca cctcttttta gcaatgaccg ttttttagga gcagtcgcaa
    20521 ctttacgaaa tcgatcagaa gtaatgaaat taatggagga gcttgggggg acgaaacaat
    20581 atataaactc catgagagct caaacccatg aattcatgaa taaacttcat gtcatttctg
    20641 gtttgattga tttgaagaag tatgaagaag tcacccattt tatccagcag ctaaatcaaa
    20701 attataaaaa agagattggc caagtctcaa gtctgatcaa agtacctgca attgccggtt
    20761 ttttattagg caaaataaac gaagccaaag aacaatctgt tgaaatgctg ttagaaagcg
    20821 attcttttat ccctaaaatg gagatggatg actccatcca ttcacttttg caagtgttag
    20881 ggaacttact tgataatgca aaagaagccg tgctacaaaa acatgaaaga aacggacagg
    20941 tccggattca tttaaactat gacacagaag ctgaagtatt catcgtgacc gtctgcgatg
    21001 acggtgtcgg gatatcagaa gaaatctcag aaaaaatatt tacgctaggt ttttcgacga
    21061 agggaatcaa tcgtgggttt ggattgaatc tcatccattc aatcgtcaaa cgccacggtg
    21121 gatttttaga attttccaaa caaacaaatg gcggtacaat cgtctatcta gaattaccaa
    21181 aaaaggaaga tcaaaatgat gacaaatgtc ctgataatcg aagatgatcc aatggttgca
    21241 gaattgaatc gtacttttgt ggaaagcatc cctaatatga acgtaatcga aagtttcaga
    21301 aatgtagaag aaggaaaaaa atatttcaga caaaaaaacg cagatctgct gctgcttgat
    21361 gtatacatgc ctggcgaaag tggtatccat tttttatctt ggcttagaca gcaaggaaat
    21421 gatatcccag tgattttgat cactgctgca gatgatatcg aaaccataaa gaatgtgatc
    21481 cgctacggtg ccttagatta tttgatcaaa ccgttcactt tgcaacgttt tcagctggcg
    21541 atcgaaaagt atcttgcttt ctctcagaca atccaaacga ctgaaaaagc cgatcagaaa
    21601 ttgatcgatc aagtattcaa ccacaccact cccattcacg aaataccatc attcatcgat
    21661 ttgcctaaag gtctgtcaaa actgacttta aaaaaaataa gtgcatttat tctaaaagaa
    21721 gatactattt tttcaacaaa agaactggct caaaaaagct cactgtcacg tatatccgtc
    21781 aagaaatatt tgaatttttt agtagaacaa gatatattga acgaaagaat caaatatttg
    21841 gaaatcggcc ggccgctaac ctgttatgaa ttgacaaaga atgggcggaa aaagctcaca
    21901 gattactgtt gagtcatcga attatcccat acaaaatagt ccaagtatac agaagtaaca
    21961 actgtttact tggactattt ttaaacattt tattgacgaa tatccatgtt ttcttatctt
    22021 aattgacggg ctttaggaag agatacctca tttttcgttt ttccagtttc tattatttca
    22081 cgaaagttct cgaaacttgt cgaaatcata tttgataatg cctcatctgt atttgaacct
    22141 acatgcgggg ttacaagaac tctagggtac atttctacta attgctggat agcagggtct
    22201 ggaatcgtct cccatggctt gaaggatcgg aaaaaaacct ctgtttcatt tgcaaaaaca
    22261 tcggttgcaa aaccagctaa atgattgctt ttcaaagctc ttaaaatagc ttcattatct
    22321 tgaagctctc cacgggctgt attaatcaag atgctacctt ttttcatttg agctaaaaat
    22381 ccttcattga tcatttgatc gttttcacct gggatatgag gtacatgaat actgacaata
    22441 tcgcttttgg ctaataactc ttcaagcgag tggaacgtca atactttttt agcagcttct
    22501 gtctgatgaa tatcgtagcc gatcactttg gctcctagtc ccttaaacaa aacagcttcc
    22561 gtcaacccta tcctgcctgt tcctatgatc cctactgtgc aatttctgat ttcacgacta
    22621 aacatttgct catccactcg aaaatctttg aaagatgttc ggatcgtcgt atacgcagta
    22681 tttctcaaaa gcatcatggc aaaagtcaaa gataactctg ctatcgcatt tggcgaatac
    22741 gatggtacac gggctactgt cataccaaaa tcagctgccg cttgtagatc gatatgattg
    22801 actcccacag tccgtgtaaa aacataacga atcccatatt cctgcatttt tgcaagattg
    22861 gtctcatctg ctatacaatt tcccctcaac aatacagcat catggtcctt tgctgacacg
    22921 atattgtcat gtgtcaacag ttcttcataa agactgagat cataatggta aatattcaat
    22981 ttttcaaaaa aatctatctc gttcggacga acaccgtaac atgcgattct catactttct
    23041 tcctccattt cttatgaaaa taaacctatg ccatgaatca tttgtaatac aacgatccat
    23101 acaggtgtca gtaccacagc aaaaatagtt gacagtaagg atgcattgga ggctaaaagt
    23161 gcctccctat caaaactgat agcataggct gctgccactg ttgcagctgg tgtagccatc
    23221 atgataacga ttgttgccag tgcttcaaaa ttgactggta gaatattcgt tgccgtcaaa
    23281 actgctagaa tcacgatatt caatgcaggt acaaatacca ctttgactag actgtaatac
    23341 catgaagttt tttcagatgc agcttttttg aagcttactt cacctaatgt tgcgccgatt
    23401 gctagccacg ccaatggtga acttaaacca gctaaataat ccatcggctg aaatagccac
    23461 ggtgcagtct ggtcaattcg caaaaacgct acttggctta tctctccttc tgcacctgta
    23521 actgacactt gtggcagata cccttggaac agccaaatga aaaggccggc aaaagtagcg
    23581 ataatgattg gattgacgaa catcgctttg atatttttag cttccatctt caagccactc
    23641 atttttatgt atccataaga atacaaaaag attcggtagc caatattgaa aattgaggaa
    23701 tacatcacgc cgacaggacc ataaatcgca ctgacgatag gcgttccgaa aaaggtcgta
    23761 gaaccaaaga tcgtcaggac acgcaacgtt gtttgcttat cccctttata gcttaagaaa
    23821 aaaggttttg aaactagaat aagaataata taaataacta atccccaaat caagacattg
    23881 attccttgca tcagtaattc tgtattgata tcttgcatga aagctcgaaa tgccagtgct
    23941 ggcaaagcca ctgttaagac gactttcgat agaatttttc caacagattc agaaaaaatc
    24001 cccttttttc tacaaacaaa ccctaataat ataataaaaa ctgttgaagt gattgcactg
    24061 acaatcgaca tatctgtcaa agtcgatcga aaaatgtcaa ataagttcat ctttctcctc
    24121 ctaattatgt tcatttattc acaataaaaa aagcttttat tttgctaata cgtattaaca
    24181 tttttaattt tatctttaca ttgttactta ttgaacaata ggaaattaaa gaaacttttg
    24241 aaacttatgt aaagtgattt ttactagaac acaaaaaaaa ccttaaaacc aaacttaaga
    24301 agtttagttt taaggttaac ttaaattata ttatgcgtgg aaacgttcca cgccatctag
    24361 ataagttgct tccaatgtca tatcagggtt caatacgata aagtctgcat cgcgtccttg
    24421 agcgattttt ccacatgtat catcgatttt acagctgatt gctggaatca gactagccat
    24481 catgactgct tgttctggtg ttgctaatcc ccagtctaca acatttttaa ttgcttcttt
    24541 caatttcaat atacttccag ctaagttgcc agattctaga cgtgctgttc cttcttttac
    24601 tactactgga aattcgccta aattgtaatt tccatcaggc atcccaccgg ccatcataca
    24661 gtctgtaatt aatgcgacat gatcatgtcc tgctttttcc attaggattc ccgcagcatt
    24721 tggatgtaca tgatggccat cacaaatcaa ttcagaaaag acatgttcta aagataataa
    24781 cgcacccacc atacctggtt cgcgatgatt caatccacgc ataccattga aagcatggac
    24841 aaatacactt gcgcctgctt caacagcttt ttgcgcttct tctagtgtag cattactgtg
    24901 tcctagagaa acaactactc cttcttcagt cacttgtttg acaaactctt ctacaccttg
    24961 acgttccggt gctaaagcaa tttttttgat taaaccacct gaagcttctt gccattcatg
    25021 gaaagtatcc aaatcaggat ccccgaaata acttgggttt tgtgcccctt tgtgttcttc
    25081 tgtgaagaaa ggaccttcaa aatagattcc tttgatttta gctcctggtg cttcctgata
    25141 cattttgccg attgtctcag ctacatcttt taaacgttct ttgcttgacg tcaatgttgt
    25201 tggtaaaaat gaagtcactc cacaagataa cagaccttca gacatcactt tgatgccttc
    25261 tgcatcatta tccattacat catgattcat atagccgtga atatgtgtat ctaccaaacc
    25321 aggagcaatc catttgccgc tttggtcaat gatgttgact tctccctcag gtagttcttt
    25381 ggtgtattca ccaaaaagtc catcggtaat ttcaagatag cctgcatgtt tgacacctga
    25441 cgctaaaaag aatttgtcag catagataaa agttctcatt ctattctctc cctttgtttt
    25501 tctacctcta aagtactctt atttagagaa gaagtcaaga atggtctaca ccatttacaa
    25561 attttttgaa atttgtttca cagcttgtgc taagccttca tagaatgctg ctctttctgg
    25621 ttcttcttta cgcttgtata ttaagctttt aagcacaaat aaatcattga ggtaatagta
    25681 gctattcttc tcttgagccc aatagattcc ttgattcacc tgttctaacg cttcgtcgat
    25741 ttcattttga tggaataaga aatttccata attataaaaa atttgcgaaa attcactttt
    25801 tgatcgttca tcagctgatt gatgcagcag ttggatgctt cgactcaaat agtagcgtgc
    25861 ttcagccgtt tttcctgcca caccatatat ttttccgata caactaatca gttgtatttc
    25921 tgtgtcagaa acatggattc tttctttttg gctagagtag cttaatgctt ctttcaaata
    25981 ataaagggac tgagagatat tttgacgcaa cgtgaattcg caaacaccga gataataata
    26041 atagcgttga aagtcagttg cttgatacag attttcagaa atatcagaag attttagtac
    26101 ttgttctaac ttccgataat cacgtttttg gaaacaacta tccaacagtt caaataattt
    26161 atcgtttgtc cgagtagttt ttcgagagag attcatcaca tgatcaatcg ttacccctag
    26221 ccgttgacaa atctgcatca tcaccaatac attcggcagt tcctcattat tttcgatccg
    26281 acttaataca ctttgtgaac aaatatcatg cgaaagcatt ttttgcgtca ttttttgttc
    26341 ttttcgaatc tctttaatga tcgttccaaa ggactcgatt aacgtttcca taagtatcct
    26401 ccccaaaata tgcgtattcg cattctattc gtattttact ttaggaagtc gcaaacttca
    26461 agaaaagact tgcaactaaa taatatactt tagttattta agaaaactcc actagaaaga
    26521 gagcctcagt gtgtttgtct gtggccctcc tactgaaaaa tttggttttt aaaatcattt
    26581 ttggcgatag gttgctagga attctctcat tttcttagct gtttgtttca aatcatccat
    26641 tttaggaaga taaacgattc gaaaatgatc tggctggttc caattaaatc caccaccatg
    26701 tacaagtaga atatgatgtt catgtaaaaa gtccaaaacg aatttttcat catccaaaat
    26761 attgaatcgc tttgtatcaa tttttgggaa tatataaaaa gcagcttttg gttttacggc
    26821 tgaaagacca ggaatatcat tgattgcatt atagatatat tctctttgtt catagatcct
    26881 tccgcctggc aggagcagct catcgacact ttgataaccg cctagcgcgg tttggataat
    26941 ttgctgagac aatacattgg aacacaaacg catggaggac aacatattca gcccttctat
    27001 atagcctttg acgtgtgact tatctccact taggaccatc cagcctactc gaaatcctgc
    27061 tacacgatga gatttggata gaccgttcag cgtaacaacg aacaaatcag gcgctaatgt
    27121 agcaatcgga atatgttcta gaccatccat cactaagcga tcatagattt cgtcggaata
    27181 aataatcagg ttattttgtc gagctacttc aacgatttct tctaataatt cttttggata
    27241 aagtgcccca gtaggattat taggattaat gataacaata gcttttgtcc gactcgttat
    27301 ttttgatttg atatcatcaa tatcaggata ccattctgcc tcttcatcgc aaatataatg
    27361 aacaggtgtg cctccagcta atgcaataga agccgtccac aacggatagt ccggcattgg
    27421 aaccagtact tcatctccat tgtccagcaa cccctgcata cacatcgtga tcaattcgct
    27481 cactccgttg ccggtgtaga tatcattgat cgtcacattc ggaaaatgtt tcagttggca
    27541 atattgctca attgcttttc tagcagaaaa gatccccttg gaatctgagt agccttctga
    27601 gtcacgggca ttcatgatca aatcacgaat gacttcgttt ggtgcttcaa atccaaaagg
    27661 tgcgggattt cccgtgttca attttaaaat actaatgccc tcttcttgca tccgctccgc
    27721 ttcttctaga acgggaccgc gaacatcgta actgacacct tctaatttgt tggatttttc
    27781 aaattctctc atcacttagc caatccctca tttcaaaaag ttagaacttt ccaaattttt
    27841 tgttatttac tatttcaata tcatactcca tcctagaaaa ttttgccact tatttaggaa
    27901 aaacgtaagt attaaaaaaa cacaaacaag cgttgagaac ttaattgtca tgatagtcat
    27961 tccatagatt cgctgcccaa tccattgcaa ttccacaaat gattcctagc ataaaaccaa
    28021 gcaaaaaacg tccgaatgca agtccaatca atacacctaa gatcattccc agtcctgaaa
    28081 attctccgtc atatttctcc atcttaataa gtcctcccat ttttgagctt gacaactatg
    28141 taaaacctcg ctatcattag tgtgttatta ttacgcagat gtgttggaat tggcagacaa
    28201 gcatgattga gggtcatgtg agcgttagct cgtgtgggtt cgagtcccat catctgcact
    28261 acaactcgtg aagttaattt tgcttcacga gtttttttgt ttgaacgttt ctttatgcca
    28321 ttatatacat atcactgtat cctttacaaa aagaacgtac aatcatgtaa acagcctgag
    28381 gtgagtatat gaaggtcgga aacaagctac tcgtagaaac ttgcaagtgt taaaacaatt
    28441 aatcgaaaaa cgagtaaaat ccctcaccta atactaaagc gagggatttt ttgtatatta
    28501 tctgtttatc accgttatta taaaggtaca aataccaagc acggttaatc caaattgcat
    28561 aaattcattt ttttgtacac tcatgctttt cattagctct ttaactgcca ttagtactaa
    28621 gatggcgata acaacataaa gtatatagta cgtccgcatt ccggaagccc atactgtggg
    28681 agaaaatccc ataattaacc ttgaacaaaa tcccattatc atcaaaataa ctaaaaaaat
    28741 agaagttttc ttattgtcaa aacttaaata aattccaaca attaaacata gtaataatgc
    28801 caagactact aaagtagcta tccaagtacc tggataaaaa agtgacagtt tcgttcctaa
    28861 ctctgtaaag agattattca ggttactact actccaaatc attgcccttt tatttccatt
    28921 gacgtaagta aagctttgac ccattgtatt accaaaataa ataatcaggt ttaagaaaaa
    28981 cggtaatgca gtcaatatac gcacataata gttttgacat ttcctatatg ttagaaggaa
    29041 aattaagaaa aatagcaata aaaataagat attcatgtct aaaaaaaacg gctttccaaa
    29101 tgatgaaata cctaaatcta acttattaag aaagttgaaa tttttatatt caggaaacca
    29161 tttattaatt tcatgtgcag cacgtaatgc attccctgga gttgtcaaag agaaaattaa
    29221 ttctgctaag cttattattg aaaatactga taacttataa ttatatcgtc cattgacaat
    29281 caaatataaa ctaactatac ttgttagaac aaaaaaacag gcgttgactt gttcttgatt
    29341 agttaaaaat atcaataaag gaatacttac ccaatatatt tttctattta tttcttctcc
    29401 tcttaagagt tgaaaaaacg gataaaaagt tagtaaacta aatgctactg gccactgata
    29461 gttcaaggtg gttgctctcc aaccggtttc ccccattact gtcaatggta ttaaacagta
    29521 tatagagcaa accaataata aatttttaac atttattttc tcaaaaacat a
//
LOCUS       DAXQKX010000030        29105 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.030, whole genome shotgun sequence.
ACCESSION   DAXQKX010000030 DAXQKX010000000
VERSION     DAXQKX010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29105
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.030"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..1030)
                     /locus_tag="ACF3MF_001508"
     CDS             complement(<1..1030)
                     /locus_tag="ACF3MF_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFE3927505.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1112..1801)
                     /locus_tag="ACF3MF_001509"
     CDS             complement(1112..1801)
                     /locus_tag="ACF3MF_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFE3927506.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="ACF3MF_001510"
     CDS             complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="ACF3MF_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HFE3927507.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2328..2831)
                     /gene="rplJ"
                     /locus_tag="ACF3MF_001511"
     CDS             complement(2328..2831)
                     /gene="rplJ"
                     /locus_tag="ACF3MF_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HFE3927508.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3035..3162)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="ACF3MF_001512"
     CDS             complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="ACF3MF_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HFE3927509.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="ACF3MF_001513"
     CDS             complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="ACF3MF_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HFE3927510.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4799..5467
                     /gene="sdaAB"
                     /locus_tag="ACF3MF_001514"
     CDS             4799..5467
                     /gene="sdaAB"
                     /locus_tag="ACF3MF_001514"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HFE3927511.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5480..6352
                     /gene="sdaAA"
                     /locus_tag="ACF3MF_001515"
     CDS             5480..6352
                     /gene="sdaAA"
                     /locus_tag="ACF3MF_001515"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HFE3927512.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6443..7543)
                     /locus_tag="ACF3MF_001516"
                     /pseudo
     CDS             complement(6443..7543)
                     /locus_tag="ACF3MF_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324221.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            complement(7635..8522)
                     /locus_tag="ACF3MF_001517"
     CDS             complement(7635..8522)
                     /locus_tag="ACF3MF_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFE3927513.1"
                     /translation="MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKT
                     AESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATG
                     DLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSAL
                     RYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMI
                     GNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHS
                     MLHENQEVDQLVSRFIWKE"
     gene            complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="ACF3MF_001518"
     CDS             complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="ACF3MF_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HFE3927514.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9245..9415)
                     /gene="secE"
                     /locus_tag="ACF3MF_001519"
     CDS             complement(9245..9415)
                     /gene="secE"
                     /locus_tag="ACF3MF_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HFE3927515.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="ACF3MF_001520"
     CDS             complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="ACF3MF_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFE3927516.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9753..10397
                     /gene="cbpA"
                     /locus_tag="ACF3MF_001521"
     CDS             9753..10397
                     /gene="cbpA"
                     /locus_tag="ACF3MF_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-AMP binding protein CbpA"
                     /protein_id="HFE3927517.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10453..10956)
                     /locus_tag="ACF3MF_001522"
     CDS             complement(10453..10956)
                     /locus_tag="ACF3MF_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HFE3927518.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10969..11015)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11553..12518
                     /locus_tag="ACF3MF_001523"
     CDS             11553..12518
                     /locus_tag="ACF3MF_001523"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFE3927519.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12617..13789)
                     /locus_tag="ACF3MF_001524"
     CDS             complement(12617..13789)
                     /locus_tag="ACF3MF_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFE3927520.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13776..14921)
                     /locus_tag="ACF3MF_001525"
     CDS             complement(13776..14921)
                     /locus_tag="ACF3MF_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFE3927521.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14935..15867)
                     /locus_tag="ACF3MF_001526"
     CDS             complement(14935..15867)
                     /locus_tag="ACF3MF_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3927522.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15984..17063
                     /locus_tag="ACF3MF_001527"
     CDS             15984..17063
                     /locus_tag="ACF3MF_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFE3927523.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17060..17689
                     /locus_tag="ACF3MF_001528"
     CDS             17060..17689
                     /locus_tag="ACF3MF_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFE3927524.1"
                     /translation="MITVVIIDDDPFVTKSLQTILESTKEIRVLGIGHCAKDALVLYE
                     THRPDVLLTDIRMPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYL
                     IKQNLQAIIPSVKSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKE
                     VAAGKNNKEIADALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(17799..18026)
                     /locus_tag="ACF3MF_001529"
     CDS             complement(17799..18026)
                     /locus_tag="ACF3MF_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFE3927525.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18129..20717)
                     /locus_tag="ACF3MF_001530"
     CDS             complement(18129..20717)
                     /locus_tag="ACF3MF_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HFE3927526.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20737..21396)
                     /locus_tag="ACF3MF_001531"
     CDS             complement(20737..21396)
                     /locus_tag="ACF3MF_001531"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFE3927527.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21445..21948)
                     /gene="trmL"
                     /locus_tag="ACF3MF_001532"
     CDS             complement(21445..21948)
                     /gene="trmL"
                     /locus_tag="ACF3MF_001532"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008175 - tRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HFE3927528.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22169..23035)
                     /locus_tag="ACF3MF_001533"
     CDS             complement(22169..23035)
                     /locus_tag="ACF3MF_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HFE3927529.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23144..23785
                     /locus_tag="ACF3MF_001534"
     CDS             23144..23785
                     /locus_tag="ACF3MF_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HFE3927530.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23847..25208)
                     /gene="mgtE"
                     /locus_tag="ACF3MF_001535"
     CDS             complement(23847..25208)
                     /gene="mgtE"
                     /locus_tag="ACF3MF_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HFE3927531.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25226..26125)
                     /locus_tag="ACF3MF_001536"
     CDS             complement(25226..26125)
                     /locus_tag="ACF3MF_001536"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFE3927532.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26127..26924)
                     /locus_tag="ACF3MF_001537"
     CDS             complement(26127..26924)
                     /locus_tag="ACF3MF_001537"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HFE3927533.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISIGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26902..27606)
                     /locus_tag="ACF3MF_001538"
     CDS             complement(26902..27606)
                     /locus_tag="ACF3MF_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HFE3927534.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27737..28312
                     /locus_tag="ACF3MF_001539"
     CDS             27737..28312
                     /locus_tag="ACF3MF_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HFE3927535.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28430..>29105
                     /locus_tag="ACF3MF_001540"
     CDS             28430..>29105
                     /locus_tag="ACF3MF_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClpXP adapter SpxH family protein"
                     /protein_id="HFE3927536.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8561 a         6168 c         5232 g         9144 t
ORIGIN      
        1 atacagtatt atttcggttg cttgctgctt cacctagccc ttgtactcgt gtttgattgg
       61 cgacttgacc aaattgattc ccgacgtcta ataaaataat agctaaaagc aaaatggcca
      121 aatggcttcc gccaaccaat aaagcaataa agcttattgt ttgcataaca agtcccatat
      181 acacgatttt tctttcagaa taagaatctg ccagtcgtcc cacgataggt gcagcaactg
      241 ctccagacaa accaaaaatc gctaatatcc ctgcttcgaa tgttccccaa ttgtaggcgg
      301 gactgctgat ataaaaaatc aacgtagacc aaaagatcga aaatgttcca aacatgaaaa
      361 atccactgac tgccgcttct cttaatagac gttgagaagc aactaaatgc ggcaaacttt
      421 taagtgaatc aaggtatgaa acagctgtac tactttgctg gacagaacgc ggcattttcc
      481 agtaaagcag aagtgtaaga attccgactg cacataaagc aaataaatag atcatccgcc
      541 aagaaaaaag actggcaaca ataccagata ccgtccgaga aagcaaaatc cccacgagta
      601 aaccgctaag caatgtaccc atgaccttcc ctcttgcttt tggtcccgct agtaccgcac
      661 cgtaaggaat gatgatttgc ggcacgatcg aaagtaatcc tattaaaaaa gaagcgcatg
      721 caaataacgt aaacgaaggc gcaaaaaaag cggccaacag agagacggca gataacgcta
      781 ccattcgaat gatcaatttt ggacgatcca ccacgtcccc taaaggaact aaaaacagta
      841 accctaacgc atagcctaat tgggtcaaca tcgtcaatat cccgactgca cttgtgctaa
      901 cagataaact agctgctact tttgttccaa tcggctggat gtaatacata ttggcaacaa
      961 caacgccaca agtgattgat aatagtaaaa taagcgaagt tgttaaaggt gttttttcat
     1021 tactcttcat tgatttcccc catttcctat cttagtttac aacttatgga aaagattgga
     1081 aatagaaaaa tacaactatt cgccacactt attatttgtg cttttgtttt ccttgttttt
     1141 tcttgcgatc tttataaatg aagacaacta accctactag cacagtaaca cttgcaacca
     1201 acgtgactgc agttttgtta tatccgtgaa acagagcttc tccaccacac gcatacaaca
     1261 cagacgaagg gatgactcca atcacgatcg acaatatgat ttgctgtaga ggcaatttca
     1321 tcgcatctgc agcaaaattg accatagaag atggaataac cggtatcata tagcctaaca
     1381 ttacacctat ttttggatgt ttcatttgtc ggattgcttg cacccaatga ttcgtttcgg
     1441 ttttcttatc taaaaatttt aagcgatgca taaggaaaat tgcagtgatg ttaccaagag
     1501 cattacccaa aatgttgatg atcgcacctg tcagtggtcc aaagctcaaa ccagcaatga
     1561 ctccaactac tgaagtagga atacctggaa cagcacacat caccgctgtc aatacgatca
     1621 agagtatcga tgcaaaagtc ccatgcgaac gaatatgtgc gagtagctct gccttactcg
     1681 ctctcggatt taaaaataat tggatgtctg tctgatattc taaatacaac cgatagccca
     1741 ctaccagtat cagaatgatt cccaacgaga tcaacatcaa tcggattatt ttctttttca
     1801 tatttcctcc tgaaaaaaat ctatattcat taaataatag tttaacataa aaacaaaaaa
     1861 gcaccgaaat ccaacatagg atctcagtgc ttttaaatag taaaaattat ttaacagtta
     1921 cagatgcgcc aacttcttca agtttagctt tcaattcttc agcttcttct ttagatacgc
     1981 cttctttaac tggtgcagga gcgccatcaa ctacagcttt agcttctttc aagcctaaac
     2041 cagttgcttc acgaactgct ttgataactt taactttttg gtctccagct gcagttaatt
     2101 ctacagtgaa ttctgtttgt tcttcagcag cagcagcgcc accagcagca gctacagcta
     2161 caggagcagc agcagatacg ccaaattctt cttcaatagc tttaactagg tcgttaagtt
     2221 ctaggatagt tgcttctttt aactcagcaa cgatgttttc aatgttcaat gccattataa
     2281 tttcctccgt ttaattgttc ttttttattt aatgctttat gcggcaatta agctgcatct
     2341 ccatcttctt tgtctgccac tgctttgaca gcgtaagcca cgttgcggac tggcgcttgt
     2401 agtacagata gcaacataga tagaagtcct tcgcgatttg gcaattttgc caatgctgtg
     2461 atttcttcca atgaagagac tttaccttcg atgataccgc ctttgatttc taatgctttt
     2521 gcttctttag caaattcgtc catgattttc gctggtgcga ctacatcttc gttactgaat
     2581 gcaacagctg taggtccagt gaatacttcg tccatgcctt caaggccagc ttttttagct
     2641 gcacgtgaaa gaatagaatt tttgataact ttcatttcta cgttagcatc acgaagttgt
     2701 ttacgtaaac gtgttacttc atcaactgtt aatccgcggt agtcaacgac tactactgat
     2761 gcagctgctg taaatttttc gcttacttca tcaacgattg ctgctttttt tgcgataatt
     2821 gcttcactca tttttgagtt tcacctcctg aattttgatg gaagagtttt ttgcactgaa
     2881 aaggcaagtc acttttatag ttactttgct caaccagtat tattcatcac ctattcactt
     2941 cgttcatagt gattctactc gctttgctcg aaaggaaact cctttcgctt tgctcaacca
     3001 gtattgttca tcatctcttc acttcgttca tagtgattca caataaaaaa ctctatgcca
     3061 ccgcagacat agagggacta ttgaatatat tcaataaacg tcctcggtag gaaattaagg
     3121 cttgatgcca cctactgtct tcggtacaag ttaattatta acctcaacta gcttagcatg
     3181 ctaaactagt tgagtcaaga attatttttc agttggatca atcaacattc taatatttaa
     3241 ttagaaagaa gcttggtcaa catggatacc aggtccaaat gttgttgtga tcgttacatt
     3301 tttcatgtat tgacctttag ctgctgatgg tttagctttt agcaatacat catggattgc
     3361 tgcaaagttt tcaactaatt tttcatcgtc aaatgaaact tttccgattg gtacatggat
     3421 atttccagct ttgtccacac ggtaagttac tttaccagct ttcacttcgt ttactgcttt
     3481 tgttacgtcc attgtaactg taccagtttt agggtttggc attaagcctt ttggtcctaa
     3541 tactcgtcct agacgaccta cagtagccat catatcaggt gttgcaacaa ctacatcaaa
     3601 gtcaaaccat ccgttttgga ttttttgaac catgtcgtcg tcacctacga aatctgcacc
     3661 agctgcttca gcttcttttg ctttgtctcc tttagcaaaa actaaaacag tttgtgtttt
     3721 accagttccg tttggtaata caacagcacc acggatttgt tggtctgctt ttttagggtc
     3781 tacgttcaaa cggtatgcaa cttcaactgt tgcatcaaat tttgcaatgt ttgtttcttt
     3841 tgctaaagct actgcttcgg caacaggata aactttactt gaatcaactt tttttaatgc
     3901 atcttgcatt tttttgctct ttttagccat tttggttcct ccttgattgt ggttataacg
     3961 gttgtacctc ccacgtgttc tatatctttc aatatagagc caactgagaa gctgctgtct
     4021 tagggtgtat agattattct acagtgatcc ccatgcttcg tgcagttcct tcaaccatgc
     4081 gcattgctgc ttcaacgtta gctgcgttta ggtcttccat ttttaattca gcgatttctc
     4141 ttacttgatc gctagaaact ttcgcaactt tatttttgtt tggttcgcct gaaccttttt
     4201 cgattttagc tgcttttttc aatagaacag cagctggcgg tgtttttgta acgaatgtga
     4261 atgaacggtc ttcgtataca gaaataacaa ccggaatgat caaacctgct tgatcagctg
     4321 tacgagcgtt gaattctttt gtgaatccca tgatattgat acccgcttga cctagtgcag
     4381 gacctactgg tggagctgga gttgctttac ctgcaggaat ttgcaattta acgatttttt
     4441 ctactttctt tgccacgaga catacctcct taagtccgtg atgtggttaa ttggagatgc
     4501 atatttctcc tcccacgttt tatctgatct gaaaaaatcc agacaaataa tgtgcaaaac
     4561 aatgcacact ggtacagtat agcaaattta tttgtttttt caagattttt ttctgctatt
     4621 tttacatttt gcttgaataa acgctaaatt tattctaaaa aaacaacaat ttttcgttct
     4681 catttcttct tttatgttac acttgcgcta gcatggttca acagatgaaa gcaaacaata
     4741 acacggtttt ttagaccctt gtacaaagat tcctacataa caaaatgagg tggagaaaat
     4801 gaaagattta aggtatagaa gtgtctttga tattattgga cctgtgatga ttggtccaag
     4861 tagctctcac actgccggag ctgctagaat cgggaaaatc atacgtagta tatttggcga
     4921 acagcctgat tctgtagata tttatctata tgaatcattt gcaaaaacct atcgggggca
     4981 cggaacagat attgcattag ttggcggcct gttagggatg gaacccgatg atgaacgttt
     5041 agctgattct ttgaaattgg catatgaagc cggtatggaa gtcttgtttg ttcctaagag
     5101 tgaaaaagcc gaacatccaa actctgtaaa gatgcttcta aaaaaaggaa cacgaaagct
     5161 ttcagtcact ggcatttcga tcggcggtgg caatatccag atttctgaat tgaatggatt
     5221 caaaatttct ttaagcatgg gtactcctac cttgatcgtt gtccaccaag atgttccagg
     5281 tatgattgct aaagtgacta gtatactttc tgagaccaat acgaatatcg gcactatgac
     5341 agtgacacgg gaatcaaaag gtgaaaatgc cattatgata attgaagtag atgatcctca
     5401 agtagaagaa acggtaaaaa gactcaaaca gctgccaaat atcgacagcg taaattattt
     5461 cgattaagga gctaaaaaaa tgtttttatc gattgaagaa ttagtagatc aagcaaaagc
     5521 ttatccaagt gtagcagaat tgatgattgc agttgaaatg gaaatgagtg gccgttcccg
     5581 tagtcacatc atcgagatca tggaaaaaaa cctctcagta atggaacaat caatcaacga
     5641 gggaaaagaa ggtgttacct ccgtcacagg aattaccggt ggtgatgcaa aaaaattaga
     5701 tgattattta aatgaggcag actttttaag tggagaaaca atcttaaaag ctgtacgcaa
     5761 tgctgtagct gttaatgaag tcaatgcaaa aatggggttg atttgtgcta caccgactgc
     5821 cggaagcgcg ggtgttgttc ctggtgtgct gatggctgtc cgagatcggc ttgatttgac
     5881 acatgaacag caattggaat tcttatttac cgctggcgct ttcgggttag tcatcgcaaa
     5941 caacgcttct atcagtggtg cagaaggggg atgtcaagca gaagttggtt ctgcaagtgc
     6001 aatggcagca gcagctttgg tttgtgcaaa aaatgggact cctcatcaag cagcacaagc
     6061 agtagccatt acattgaaaa atatgatggg actgatttgc gatcccgttg caggcttagt
     6121 tgaagtcccg tgtgtcaaac gtaatgcttt aggctcttct caagctttta tctctgctga
     6181 tatggcatta gcgggtatcg aaagtgtcat tccgccggat gaagtcgttg ctgcaatgta
     6241 ccaagtcgga cgtcaaatgc cgtcgatttt caaagaaaca gcagaaggtg gcttagctgt
     6301 tacgccaact gctaaacgac ttgcggaaga gattttaaat aagagggcgt gataaagctc
     6361 cttaatttcg agtattaaga gattagttat cttcataaca aaaaacgaag agaggactaa
     6421 ttgcccttct cttcgttttt tattaatcca tcaatttcgt attttttact tcatcgatcg
     6481 tttttgttcc tgcaagttgc atcgtgatcg acaattcttt gttcaggtgt tcaaaaacag
     6541 atgttactcc ttctgcccca cctagattca acccataaat cactggtcgg ccaatcgcaa
     6601 ctaagtcagc accacttgcc agagctttga agacatgctc tcctcgacgg acaccagagt
     6661 cgaaaatcac tggtacacgt ttgttgacta cttcggcaat ttttggcaat acttcaaagg
     6721 acgcaggacc tccatctaat tgacgtccac catgattgga tacccagata ccatctgccc
     6781 ctgcagagat agcgattact gcatcttctg gcgattgtat tccttttacg ataactggaa
     6841 gatgggtgat ttctttgatt gttttgatgt catctggtgt caagccttgt tttgcagctg
     6901 cataaatttc tgcgattcct tttccttcgc cattaccact tgcactttgt tcgctatacg
     6961 cagctaagtt aggcattggt aatggaaatt ggaattgatt gatgacgtct tcttcacggt
     7021 aaccaccgag cgttgaatct gccgttaaaa tgatagcttt agcccctgct tctactgctt
     7081 tgttcaaaat gaactcattg aatctgtcgt ctttactcat atataattgg aaaaactgcg
     7141 gtgcgcctgg cgctgcatcg gctgcgtctt tgattgtcgt atttgcataa gtgctgatgg
     7201 aaaagattga tccagcagca gctactcctt tagctgtatc agcttcccct ttttcatgtg
     7261 ccaatccttg ggccgctgat ggcgcttgga taatcggtgt atctaattca attccgaaaa
     7321 cagatgtatg caaatcggct gagtcgattc cgcgtaatat ccgtggcatg attttctttg
     7381 tattaaaaga agtcgtattt tctttcatcg tccactcatc ttcagaacca ccgcgaatat
     7441 agccaaaagc tcctgcttcc atgcgctctt ttacacgacc ttctagttag gcaatgttta
     7501 caatatcgat tggatgttct tcattacttg tatgataagt catagtagat ccttctttca
     7561 tcttcttgat tacatataaa tcatactaaa cttacaaaaa gtaagcaaac atttactctc
     7621 agatactttt atcgctattc tttccaaata aatcgactta caagctgatc tacttcttgg
     7681 ttttcatgaa gcatactatg agaggcattt tcacctgtca ctactttttc ctctatttca
     7741 tttccgcgtt gcttcaacaa cgcatagacc gctaatgcac tgtttaacgg tactgttcca
     7801 tcactcaagt ctgtttcatc tagttgacca gcaatcaaga aaaatcgagt ggttatagga
     7861 atattaccga tcatttgctg gtaatcttga tagcggttag aaacgacagc aggccccttt
     7921 gctaactcat ctgtcagaga ctgcgcacta tcatcgacaa aatcattaaa aggcgcgcca
     7981 attgctgtta atgtctgaac ttgtggcaat gacgtatcct gtccatacgt tcctaaatag
     8041 cgtagtgcac taactcctcc catggaatgc cccactatgt tgactttatc tatgccgtag
     8101 ttttctttca gatacaaaag acaagttttg atccattctg cttgattcca ctcgttattt
     8161 ttattatctt caaacaatac ttggaccatc ggattgtctg cttttccaga caaatctcct
     8221 gttgcttgta tttgtccatc tgttcctact gttaaaacca attcttttac tgcttgctga
     8281 tttttttcca aacgccgcaa catcccttta aaggaatttt ctgtcccgct gtagccgtgg
     8341 aaaaaaagtg ttggaatagt ggttttttct atcactttac tggattctgc cgttttttct
     8401 ttatcagaaa cttcagtagt atttatcttc gtcgtctggc aaccacttaa cgcaaacaaa
     8461 ctgataagga ctaaagctgc tgcagttgca cgtttgcata aatttttgat tggttctgtc
     8521 atacacctct tcctttccat atagaaaaaa gaaagacttg aaaggccaat catatgatcg
     8581 acatttcaag tctctttatt aatcgatttt atctacttga tcgaaatcaa gttctgtact
     8641 ggtttcacgt ccaaacatat cgatgttgac tttcaatttt tctttttctc cgtcaacttc
     8701 tgttacttgt ccttctaatc cagcaaatgc gccttcgatg attttcacga cttcgccaac
     8761 ttctacttct agatcatttt gtcgcaggct cataccgata gaacgcaaga tatgattgac
     8821 ttcttctgga agtaatggtg ctggtttgct tccggctccg tgtgaaccaa cgaatcctgt
     8881 cacaccaggt gtgttgcgga caacatacca tgaagcgtct gtcatgatca tttcaacaag
     8941 tacgtatcct gggaatgttt tatgaacgat ttctttttct ttcccatttt tgacttcagt
     9001 ttctttttct tcaggaacaa cgacacggaa aataaagtcg gccattttca tactttgcgc
     9061 acgagattcg atatttgctt ttactttgtt ttcatatcct gaatatgtat gcaagacata
     9121 ccagtttttt tcaaaagatt ccattgaagg ctcctcattt cattgtaaaa taaaaaaacc
     9181 tcagtacacc cgaagttttt ctttcgcttc attatagcac taaaagtacg ttgtggctag
     9241 cgagttattt taaaatccag ccaaataagc tttggatggc tgtatccatt acgtaaaaca
     9301 tcaatccgaa aataatagaa gtttcgatga ctactaacgt atctttacgg agttgttttc
     9361 tgcttggcca agttacttgt ttgatttcat cttttacgct ttttagaaat ttcatgagac
     9421 aacctccctt gctactgttt atttcgtttc tttatgtaat gtatattgat tacaatattt
     9481 acaaaactta ttgatttcca aacgttcgcc gctttttcct tcactgactg attttgtgta
     9541 gttgcgagac ccacaaacgg aacaagcgag tgctgctttt ttctttgcca tttacttctg
     9601 cccccttgct gagaatcaga cttatacttc ataacagtat cacgtaactt tttacttgtc
     9661 aatttgtgaa ataaactatc tattgttttg gataaaatta tgatatgatt aatttgaaat
     9721 taagctaaaa tgagacaatt ggaggtatag cgatgctatt aaaaacactt gtatataaga
     9781 aaaaagatct gacaaccgtt acagagacta gtacattaga agaagcatta aaaattttag
     9841 aaacttccgg ataccgttgt gtgccgatct tagattcttc aggtaatatt ttccgtggaa
     9901 acatttacaa aatgcatatc tatcgtcata aagcaaatgg cggtgatatg acgcttcctg
     9961 tcactcatct tttgaaaaac gctacaaagt tcatttacct ggatacttct ttcttcaaag
    10021 tattctttac gatcaaagag cttccttata ttgctgtcct tgacagtgaa aatcattttt
    10081 atggtatttt gacacatagt acgttgctta atatgctctc tcaatcttgg agcgtagaac
    10141 aaggaagcta tgtactgaca attgcttcca caggaaagca aggagatttg gctgctattg
    10201 caaaaatcat ttcaaaacac agcagcattg ccagctgtat tactcttgat atcgaaaaag
    10261 acgaatacat tcgacgtaca ttgatcacgc taccggctaa cactgaagcg aaagtatgtg
    10321 aaacgatcgt caaccactta gagaaaaaga attataaagt ggtagaaatt gaaaatttgc
    10381 aaaaccaaga agcataatca aaaagcgaaa aaagaaaaca gctaatctgc tttctttttt
    10441 cgctttttat aattagacac gcttttcaaa atcaagcgcg cgatctaaat aatacatcaa
    10501 tggtgctgaa acagccatga cgataaactc acttaatgca agcgtgccat aggttgtcca
    10561 aaatgcttgg ccacctgttg gaactaacat ataagcaatc agtcccatgc tgatggtaaa
    10621 gaagatcgtg ttcaatacta aacgcatctt tacatttttc actttgtttt gcaataaagc
    10681 tgtcaggcct aaagaaagca atgtttggcc gccaccaaaa accacatcca tgataccaaa
    10741 accaaagaag gcattataga cgatgacccc gcctaaaact ccccaaagca atttacggtt
    10801 aaagacaact aaatgattca aactttctga aatacgaaac tggatcggcc ctgaggatac
    10861 aggcgcaact aaaatagtta acgctagata aagagccatg atgatgccat ttacaacgat
    10921 tacggataac cgttgtctgc ttttcgtttt ttgcattttc tctcctcttt tctcctagtt
    10981 tttttaacgc gggatggttg atgaaccgcg gttatgtgaa acaaacaata attataacag
    11041 acttttcatt tatttcaatc cgtcttatct gcttttaaaa aagcaaaagc ttaaacaatg
    11101 taaacgtttg ctaaaaatcg tgggatatgg tataaagtaa gtgtaagggg tcataagaat
    11161 tcccagtaaa gcagacgaag taggatctgc aagaacagaa ttgttgtgaa acttaaataa
    11221 ataaaaaagg atgtgggaat ttgagcaacc tcttactaga gaacggtcta gcaagcagct
    11281 gaagatctaa gtggacatgc cgaaccttgg aacttctcct tacgtaagta atggatcatg
    11341 cgcttgctag gcttttttgt gtttttcggt cttcggacct ttttcatttt cctagacttc
    11401 tgctataata accaagaatt aattttgtaa cagatttttt tgaaaaaaca agtttctttc
    11461 attcaaaaaa tagaaaaagc ttgctaatta ttggttaacc agcaaacagg agtattaaaa
    11521 tatcttgttt tattgaatag caggaggaaa tcatgaaatt ccattatcat atattgatca
    11581 atccatcggc aggcagcgga aatggctata aagtagcaga aagaatttta ccggtattaa
    11641 aaaataagca tattgactat acacttcatt atagtgaata caaaggacac gatgctgaga
    11701 ttgctgaaac tttggcaaaa gaaacattga ttccttggat agaagaagaa cagaaaacaa
    11761 tcgatacttt cccccttttg atcatcgtag gaggtgacgg caccttacat caggtacttg
    11821 atactttcta tcagatggaa gtagaattcc cagttgctta tattccagca ggttctggaa
    11881 atgattttgc tcgaggggca ggccttccaa aaaatcccaa aaaaggactt cagctgattt
    11941 tagcagctca atcaccagaa aaagtccaca taatggctta tgaagaaaaa ataagtgaaa
    12001 aaaaaggaat agctgttaat aatttcggta taggattaga tgcagctatc gtccatgcga
    12061 caaatcattc ttccacaaaa aagcgattga acaaatacaa cttaggatca ttttcgtatt
    12121 tattctctat tctccgtgct ttattcactc aaaaaggatt tccaattctg gtagatgcag
    12181 gaggaaaaca attaagtttt tcaaacgcat ttttatgtac agcaacgaag catccttttt
    12241 ttggcggagg aatcgcgatt gttccaactg ctgatgcgtc taaaccagtc attgattttg
    12301 tcgtggtcga acgaatcaat ttctttaaaa tcttgtggct cattctttta cttatacaga
    12361 aaaaacaatt gaaatcgaaa tatttccatc actacacaac aaacagatta cgtatcgttt
    12421 caacaacacc gcaacatggt caagaagatg gagaagaaat ggaaaaacga ccttttgata
    12481 tcacaataac cacaactaaa cagttgtttt ggtgttaata aaagaggttt tgtcagaagc
    12541 tacatctgga acaccgttta ttcggaaaaa aggactgtga cacgactttt gtcacagtcc
    12601 tttttttact atgcagttaa ttctttgccc aattgggttg ccatcgatag tttctttctt
    12661 tacccaaaat aaattggatc attgaaaaca ccgcagcaaa agcaactaag acacaaccat
    12721 tgaaccaaaa agattctgca aatgtttgat tgtaactgag tgtttcactg atcaagttat
    12781 tattttgaac aaaccaatat gttggtgtga atgccgctat tttgctaacc atttctggca
    12841 agtattctgc tggtacaaac accccaccga taaagcaact gcctgtgata aaaatatctt
    12901 tgatcccacc gctggtttct gagtttttta ccaatgaagt gatacaagcc gaaaagctaa
    12961 tgatcggcaa taaaaacaag aaagtattta aaatatgata ccataccgtt atatcccacg
    13021 aggtgtggat cactaacaga accattagaa gtaagaagcc actgaacaac agcagcgagt
    13081 aactaatcaa actaaaggtt actttgcgat tcaagtttcg tttggtaatg ggcgcactct
    13141 ggtttcgttt actgatctct ttgcgattaa acgctagatt gatgacgctg aaaccgctaa
    13201 aaatggatag aaacaaccca taagacaaga aattaaaggt tgtgcccgtc aacagctttt
    13261 tcatccgctg actatatccc gcacttagct caacttctcc agtaaccgag agtgccattt
    13321 gtgtctgttc catagctgca tcgattgttt tatcttcttc ttgaaacaga atcagtgttt
    13381 gcaaaaaggt gttcacttgc tgtgtaacaa ctgttttaga aaaggcatct gggcgactct
    13441 gtatcttgat cgtcgccatc tttcctactt cgacttgttc ggtaaagtct gcaggcagat
    13501 gtaagataat gtttacacga ttaaaataaa gagcatcatc gatttctttt tgtgaggttc
    13561 catccaatgt aacgactgtt tccttgtcat tcaaatattt acgaaggcca tcgactacag
    13621 gcgactcttc ttcactaatc aaggcgattt tcgcatcttg cagagaggta ttttcaacat
    13681 caatattttg cgcaaaaaag aatgtggcaa caacagtgat aattacacct atcagtaaat
    13741 tcgatttatt tgctttaagc aatgtccaaa tcgttttata aagcgtcata acgcacccct
    13801 ctttccatcc aagcatttcc taacgcaaaa aggaaaataa atccgatcaa ccatagaaga
    13861 ttggtataaa aactagccaa atcagtgtag aaataaagtt tatacaaact ttcgctgatc
    13921 aagttgacga gatttaattg accaacaatc ggaatatgaa gatcaatcca atacttcact
    13981 tgttccgacc ccatcatacc agcaaaaaag ctcatcgcaa tcgtcactga aatcaagatg
    14041 ctatcctttt gcaccagatt catttttggt atcaaattac caaccaatgt acctaacaaa
    14101 atcgcacaca acgaccccag agcggtaaca atcatcaacc attgccaacg ttcaccaaag
    14161 tctacttgat agataaaacg aaagacagct aacataatat aaatctctgt caaaacaatc
    14221 gtaaagcttg ctgccaaatt agcgattgaa actaacgatt gctttctagg aatcaaggac
    14281 aagcgaatac catttgacga ttgatttgct tgctgatcct gtacattgcg gaccccccac
    14341 atcgtcccgt agagaatcgc cattccaatc agagtgaaga aataaaaact tttgaaactc
    14401 atattacgac ctgcatgaac ttcttgaaaa gatacttctt gttcaaaaac agtcatgatg
    14461 ggcgcgagat caacgttctc cacttctgcc actttactcg aaattatacc aatacgctgt
    14521 aaaaattgat ccatgacgtt tttcatcaac gtctgactca ttcctgcttg acccacatgg
    14581 agcgaaacag atgaaccatc aatgagataa aaaccagcca aatcatctgc atttagcttt
    14641 tcattcgctt ctacttccga tagttcctgt acttcaaata atggtttatc attgacttcg
    14701 acttgttcta agactgtggt aaaattttcc gaaagcgctg tttgatccgc tttgattaca
    14761 attccagtat taatcgtttc aagattgcca ccttgatcaa tctcgccaaa ggccgccata
    14821 aacatcaatc ctaaaagaat tggaaaggcc aatgtccaaa acaacatgga tttatttcgc
    14881 agcagtattt ttgtgcgata tttataaaaa tgccaaaaca ttatttcccc tcctctagtc
    14941 tctcaaatcc ttgccagtaa tctctaaaaa gacatcattc aaggacgctt ctttggttgc
    15001 tatttttccg taactgatct tttcttcttg taagattgta agaatcggca acaatactgt
    15061 atttagttca gtagttgtta cttggagctg acctttttta taagcgattc catcagaagc
    15121 tattgttcgc tgaatcgctg acaacacatt ttctgggagt aatgggatgt cgatcgtcaa
    15181 acgatccgcc gtccgtacca tatcttttag agattctttg gttcctttag caatcacctg
    15241 tccttgatcc atgatcacga tctggtcgca aagaatttct acttcttcca tgtaatgtgt
    15301 tgtatagaca atggttgctc cttgtcgatt cagctccttg atactttcta aaattttatt
    15361 ccgactttgg gggtctacag ctactgtcgg ctcatctaaa aaaattaacc gcggcttgtg
    15421 ggcaatccca catgcgatgt tcaaccgacg tttcaagcca ccactaagtt ctcctggacg
    15481 aaacgaaaca tatttttcta atcccactaa ttgaatcacc tcttcaatca aggctttcct
    15541 tttctctttt tcggaaacat ataaaccgca aaaataatcg atattttctt gcacacttag
    15601 ttcgtcaaag accgcaacgt cttgaggaac gaccccaatc attgccttga cagcataatt
    15661 ttcaggagtc attgttgtcc cgaacaattt aatggttcct ttgtcataat ttaacaaaga
    15721 aagcatacag ttgatggcag tcgatttccc actgccgttt ggacctaaca gacctaagac
    15781 ttctccttct tgtacttgca gatcaaaatg attcaatgct acaaaatctc catagcgttt
    15841 gactaattta tcaatttcga taatcatcat gaaaaactcc ttccaaattt cttgttgatc
    15901 tgactataat aaagtgcaag aaaagaaact agtgacgatt ggctaaacca cacatgacat
    15961 ttgtcacaat gaaggagtct gctatgcata aatctcggct actcaacgaa actagctttc
    16021 tactggttat ctcattgctt ttgctggtaa gtcaaggatt cgttgctatg caagttatct
    16081 atttattgat cgccgtttta ttcactggtg tcagttattt actgcctaca aagccaaatt
    16141 ggattttcca agttattcta tttcttttat gtgccttttt acctgatctt gtcctgtttc
    16201 tgccagcgac gatgcgagtg atcgcccctg aagaaagcca ccttgattac ttgtttttgt
    16261 taggtttttt gttgatttcg acggttggta atcatccccc catcaaggtc gcctttgtcg
    16321 taattttgct gtttttttcc ttttacttac gaaaaaaaga tcaacgaacg accgatcttg
    16381 agaaaaagta cattgtctcc aaagatactc attgggaaaa acaacaagag ttatcggaac
    16441 aaaataaagc attggccctg tcacaagaaa cacaattagc cttgcaaatt gtggaagaac
    16501 ggaaccgaat tgcccgagac atccatgaca atgtcggtca tctgctgtca agtgcgattt
    16561 tacaaattgg tgcgcttgaa atgatcaatc aagaaccaaa actaaaagaa ccattagaaa
    16621 atttaagtgc caccgttcac actgggatgg atcggattcg tcaaagtgtc catgacctcc
    16681 atgagacatc gatctctttt caacactcct tagagtttct gatcgctgat tttccttctt
    16741 ctgttacgat tgaaggaaac ttgtttgaag gattgaatga aacgcagcaa aactgcttct
    16801 taatggtcat caaagaagcc ttaaccaaca gtatcaaaca tagtcatgcc aaaaccgttg
    16861 ttttacattt tcgaacgttg ccggcctttt atcgcttgca aatcacgaat gatggcacca
    16921 gcccacaaaa aaattctgct cccggtattg gtttgaaaac gatgcgtcaa cgtgttcaag
    16981 aacaaaaggg acaagtccat attttccaag aaaaccagca atttcagtta acgatcattt
    17041 taccaaggga gggacaccaa tgataacagt agtcattatt gatgatgatc catttgtgac
    17101 gaaatcgtta caaaccattt tagaaagcac gaaagagatc cgtgtgttag gcattggtca
    17161 ttgtgccaag gatgcgctag tcttatacga aacccatcgt cccgatgttt tgctgacgga
    17221 catccgcatg cctaaacaaa cgggcatcga tgctgccaaa gaaattttgg ctaaatttcc
    17281 caaagccatc cttttgcttt tgacgacatt caaagatgaa gaatacatcc gcgaagcatt
    17341 ttccatcggt gtcaaagggt atttaatcaa acagaacttg caagcgatta ttccttctgt
    17401 caaatccgct tataatggac aggccgtatt tggtaatgaa atcatcgaga ctttcactca
    17461 aatgatgaag aataaaccga cgattgatag tcatgcttat gcttctttta gtgaacgtga
    17521 gcttgcaatc atcaaagaag tagctgccgg gaaaaacaat aaagaaattg cagatgcctt
    17581 gtacttgagt gacggcactg ttcgcaatta catcagccaa ttactagaaa agctagattt
    17641 acgggatcgc acgcaattgg ctatctattt ttatcagcat ttgcaataag tcttatctaa
    17701 cacaaaaaaa cctgaatgat gctccttcgc atcattcagg tttttttcac atcttctatt
    17761 caattgtccc gcaaaccatt tcctcacgat tgaaagaatc aaggattcgc agggctgcca
    17821 ggattcgttg gattgttcgg cgtgttaggc ggaaaaatag gcgccttgtc taacgttttt
    17881 tctagttttg attcttcacg atcgtctcgt tctacatcag gactttcatt caatttgaat
    17941 tctttttcca tctcatctaa ctttttaaag tcattgccag attcttttgc taatttcgct
    18001 aatttatctt cggtttcttt agccataaag taacgccccc cttttgattt cagcttagca
    18061 tatcacactg aaaaaacaaa agaaaacgct aaccaacgat catttttagc tatttctcat
    18121 ctttaaaatc aagcattttt tgccggtata aaatcgtagg gagaactgtt ttccatacca
    18181 atcatcggat ctactaactg gttatcgatc acttctgctg taagaacgaa atctttagaa
    18241 acagcaggtt ctacctcttc tttcttttct tctccaacaa atgaagaaaa cagatctggt
    18301 tccactgttt ccattacttg gtttttcgtt tcattcgtcc cactgtcatc ttctacaggt
    18361 agcttttctt ttacaacccg tggctctttt gtatagttcc catcttcaaa tggatcattt
    18421 ccgaccaaag aatcttcata agctgctagt ttggtccgga gagtgatatt cattttatca
    18481 ttatccatga tccttgattt caacgtagtc atccggcttg ctgattcatt cgctacacaa
    18541 gtgacatagg cttgctcttc ccctaacaaa atcaacagtt ccttactgcg agtcactgcc
    18601 gtgtagagca aattacgctg aagcatccgc tgatattgat ggaccatggg caaaataacc
    18661 atcttgaatt cactgccttg tgatttatgg attgagcaac aataagaaag agtgatttta
    18721 ttccattcgt ttcttttata agtgacctca tttgcatcaa actggataac taattcatcc
    18781 actttatctt cagaatcttt tgccaagatg atacccgtga tttctcccat atctccattg
    18841 aatacattca attcgggagt attgactaat tggaggactt tgtctcctat ccgataaacg
    18901 gtgtcgttcc aatgtacttc cttttttcca ggtttccctg gattgaatat ctcctgcatc
    18961 attttattta acgcatcgat ccctgcaggt ccccgataca ttggtgctaa tacttggata
    19021 tcttgtgcac ggaatccctt atttttcgct ttttccacaa ttttagagat caagggttca
    19081 atttgataag catcacttcg gaaataggaa cgatcttttt gattctttgt gaaatctttt
    19141 ggcagacgtc cttctttgat ctcatgggca agaggaataa tactagaacc atcaccttgc
    19201 cgataaatct gattgagttc cattttggga atttgttcga tttccaaaag atcatggagt
    19261 acttgaccag gaccgacaga gggaagctga tctttgtctc ctactaagat aacttgcata
    19321 ttcgtcggaa tcgctttgaa taatgtgtta gccagccatg tatcgaccat agacatctca
    19381 tcaacaatca aaagtccgcc ttctaattct ttcgtactga ctgaaggtgt tttttcccgt
    19441 ccattcagcc ccagaagacg atggatcgta ctggcaggca gacctgtcgt ttcgttcatt
    19501 cgtttagctg ctcggccagt tggtgctgca agtagaatag gaaaaatttc ttgggtatat
    19561 tttgaaggat ccaattccag tccgttcaac tctgcaaaaa gattgacgat tccgttgatc
    19621 acagtagttt tccccgtacc tggtcctcct gttaaaataa atagagggga acggattgct
    19681 tcagcgatag cttgttcttg cgaaggtcca tactgtatgc cgaatatttt ttcgatacgc
    19741 cgaatattct tctgcacttc tttttcagga taatggattt cttttttacg actgagaagg
    19801 cgctggatcg aattaccgat cccccattca gaaaagtaca aactgttttc gtaaagatta
    19861 gtctcttctt gttgtatctt tccttcttca acaagttgga taattacagt agcaacctga
    19921 tcaggctgga tttcaattgg gcgacttgtt tctaaaatac ggatcgtttg ctgaagcaat
    19981 gtctccgccg gtacgtatgt atctcctgtt tgaactgcat gctgaaaaat ctgatgcaag
    20041 atagctgctc gaattcttct cggtgaatct gctgcaatac cgatttgttc ggctagatta
    20101 tctgcacgtt tgaacccgat tccttctatg tcttcgacta gctggtacgg attttcttcg
    20161 atgatatcca aagactcgtt cttataggcc tggtagatac tgaaagctaa ctgactaccg
    20221 aacccgtaac gattcagtcc catgatcact tgatccatcc cgtggtttag ccgaatcgtc
    20281 tcagcaagca tttctctttt tggcttcgtc aaaccggaga tttgttttaa taccgaagga
    20341 tcagcaatga ttttttcgat agcatcttct cccagcaatt ctacaatttt ttctgctgtt
    20401 ttcttcccga ttcctgggaa tttttcgctg gaaagatacg ctacgatccc atttgcagtt
    20461 gttggctttt cttgctcata tctttcgagt ttaagctgcc ttccgtattt aggatgatcc
    20521 actaattctc cataaaaacg ataagtctca ttttcttgaa tatcgccgaa acttccggtg
    20581 actacaatct ctttttcacg gtaatcagct gtggtttcac tgatgtgtac caaaagcact
    20641 ttgtaaaaat tactaggatt ttgaaaaaaa atcgcggcaa ctgtaccaac gaaataaggc
    20701 atttcttctg gctgcatcgg aagccgcctc cttcttctat agtaaaggtt ctggtgctgt
    20761 ttcagttcct aaaaaatctg tttggttcca tactttcagt tcatatggca ataatctgca
    20821 aggctcttca gtctctaaaa tcgtcaaact actattgaac aatccaccca tttcacgcaa
    20881 ctcacttagc tcttttcctg tcatccattg aatggctgca gttaaagaag ctccatgtcc
    20941 tacgaataaa agtgggccat ctttatgtcg ggcaaccgca tctgctacaa cagtttcgat
    21001 acgtgtgatt gccgattcaa tcgtttctcc gtgaaaagga gaaggatcat acagatctaa
    21061 atgattacgc aaattcggca gattatccgg atatttctgg tacatttcat cgatcgactg
    21121 accttctaaa gtacccagcc ctagttctct tagcttatct gtataaaaaa tctctaccgg
    21181 acgagcaagc tctttgttga taccttctgc tgtatcacgt gctcgctttg ctgtactgga
    21241 ataaattgct ttaaaaggaa catattttac ctttttccca aatgctttga tttcttcgta
    21301 actttgtggc aaaagcggag aatcgccatt gctcccttga aaacgtcttt cctgattcca
    21361 ttgtgtcttc ccatgtcggg taaaatatag ttccatacgc agcaaactcc tgtctttctt
    21421 ttattttact ctataataaa ctgtctaatc cagcttgtca ttttcatagt gatgcgtcaa
    21481 ttctaaatta gggaatcctt gctggcgaag tgcttcatac actatcattg cagctgtatt
    21541 cgataaattc aatgagcgga catgctcatc attcataggg atgcgtaaac acttttcttc
    21601 gttttcacgc ataaatgttt ctggcaaacc ggttgtttct tttccaaata aaaagaagtg
    21661 ctcttctcca tcagcaaaat tttcgtcact atatacttta tgggcaaatt ttgagatcaa
    21721 atgtagttta cgattaccta aaaatgttaa aaaagcttct aaattactgt ggtaagtaat
    21781 atttacatca ttccaataat ccaaccctgc ccgttttaga tgtttgtcat cagttgaaaa
    21841 acctagtggc tcgattaaat gaagcggagt attcgtggct gcacacgtac gggcaatatt
    21901 tccagtgttt gcagggatta atggttcaaa taaaacgata tgattcatca ggatcattcc
    21961 tctcatattt atgttcgttt ctattttctg acaatttgat ttttgcataa aaaaaaacgt
    22021 atcaactcgg tgtcagtcac tgcgagtcgt tacgttagtg aagctcttct cactaacttt
    22081 tatcagaaca ggaacctgat aaaaaccaat gaaaaaacaa cttgttgcta atataacacc
    22141 ctcaactttt ttttgcaacc tctactcatt aaaaactgct agaaaaacgt tttctcttag
    22201 ttccttttaa taattctatg tcaattgtaa tcttcttcaa aggattctta tataagtctg
    22261 ctttgattcg ctcttctacc tgccattcta aaggtgacat ggccaaaaga tctttttgat
    22321 tttcctctgg tatctcaaat tcataggtta cacgctgacg ttcagttaat ttcattgctt
    22381 cagcaaactt ggctactaca cgttcattgg aataactctg tttttcaggt tgattcggat
    22441 aaaaagcctg acgtagttcc tttaaataat tttcttgtgg caccaccttc aacacttctc
    22501 catcttctga gagtacacgt tggaattctt ggtaatgaga aggcgaaaag atatttaaaa
    22561 ccgcgttgaa tgtttgatca gcaaacggca aattggtcaa atcagctaca caccaaaatg
    22621 cttcggcaga ttgttctgta gctgcgtaga ctccttcttt tgaaatatca aatccaacag
    22681 cattttgaat ctttttcaat tttgaaagtt cattcaagaa gctaccttct ccgcagccaa
    22741 catctaatag cgagacttct tcaggtaaat gctgcgcaat agtctcaata acgggctgat
    22801 acatgccaga ttggatcatt ctacgccttg gaacgaacat tccttgatcg tattctgttt
    22861 taaccgcatg ggataaaaaa taaagtgttc cttttttgga aaggtcaaaa cggtgattat
    22921 ttttgcatat caagccatta tcagactttt ttacttcttc ttggcaaacc ggacagcgga
    22981 acagctgatg attttctgcc aaaaactggc gtcctcggtc aatttttttt aacatagttc
    23041 cccctcattt ctgttttatc ttaccgttag atgctcactt tggcaactgc taaaaatatg
    23101 atacaatgcc tagaagaaag tgaaagataa aggagaagat tagatgatca aagaattttg
    23161 cgctgaaaac tacacatcta ttcctctagc aattgctaga ggagccgatc ggatcgaatt
    23221 gtgtgacaac ttagcggtcg gtggcacaac cccgagtact ggtgtgatcg aagaaacgtt
    23281 aagttatgct ggggaaaaag atatccccgt aatgacgatt attcgtccta gagggggcga
    23341 cttcgtctat aacgatatcg aattgaaaat catgcatact gatttgattg aagcaaagaa
    23401 attagggacg gatggcgtag tatttggttg tcttactcct tcaggctggc tagacgaaga
    23461 ggccttagaa ctattgatcg aaacagcaga agggttgcag atcaccttcc atatggcttt
    23521 tgacagtatt cctgaagatc ggcaattcga agcaatcgat tggctggtag aacatggtgt
    23581 tgaccgtatc ttgactcatg gcggtcctgc tgacaaaact attgtagaaa atttcccacg
    23641 gcttaaagaa ttgattgcct atacagatgg ccgcttaatc attttgcctg gtggtggtgt
    23701 cactgcagag aatgcagcac atgtagctaa agaattgaac gtaagcgaag tacacggaac
    23761 caaaatcgtg gatcttcagt tataatctta taaacaaaaa aacatttgca acaggcataa
    23821 tgcttattgc aaatgttttt gtttttttac ataaaatagc ccataaataa agaagcaata
    23881 ttgaaataaa tcagtacact cgtcaaatcg ctcaaagtcg tgataaaggg accgcttgct
    23941 actgctggat caaatcctag acgatccatt agcatcggga ttaaactacc tgcaagattc
    24001 gccactgtga ttgcaaatag catagccatc cctatgacaa accccaagat aaaattatgt
    24061 ttccaaaaac ctacgattag aaaaatcgtg atccccgtaa cagctcctgt gacaacgccg
    24121 gtcaagactt cagccaaaac aagtcgaaca aatccatgat ctttctcatc agaaatcgca
    24181 agtcgacgaa cagccacagc tagcgactgg gttccagcat taccggcagt tcctgtaatc
    24241 agcgaaatga agactgctaa aatactcgct tcacttacca agtcttcata gtgactgatt
    24301 aaagaagcgg tcgacatacc taaaaacaac agagtgatca gccaaggcaa acgtcgagac
    24361 gctgccttta ctggattttc attaatttct tccacattga ccccggcaag tcctgaataa
    24421 tcgctagcag cttcatcatc aataacgtcg atgatatcat cgactgtgac gattcctaac
    24481 aaatgatcat cataatcggt aacaggaaga gctaagaagt cataatctct aaatgtttgt
    24541 gccacatctt cttggtcgtc gcctacatga actgaaagca ctcgttcgct catcagatca
    24601 gaaatcattg cgtcgtcatc attcacgatt aggtcgcgca gagaaataac ccctactagc
    24661 tgaccttctt gattaacgac atagatgtaa tagattgttt cagctacatc tgcttcgttc
    24721 ttcagcacgt acatcgcaga gcgaacagtt tgattggcta cgatcgaaac aaattcagtt
    24781 gtcatgatcg cgccagccgt ttcatcctcg taatggagaa gttccttgat ttcactggca
    24841 tcgtctgccg acatcaaact taaatattta gcaatttgct ttttatccag cgtattaagc
    24901 aagtcaacag cattatctgt atacatctca gaaagcatat cagctgcata gctaggacgc
    24961 atttcatcta ggtattcttt catatgttcg ttgtcttctt caatcacatc gaacatatcc
    25021 gctaattctt taggcgacag ataggaatag atcagctgcc tgttctcttc tgtaagagat
    25081 tggtagaatt gcccctgctc atagatatgc atctctaaaa aactgtttct gaatgcctga
    25141 atattatttt cccttaaatc ttgagtcaac tgggcaaatc tttcctctaa ttcttgattt
    25201 tcatccaaac caatctcacc tcgccttatt cttcaaaccg tctcacaact gcctccatgt
    25261 ctgcggctaa aggctgcttg aactccagca actcttctgt aaatggatgg taaaaacgca
    25321 gatcataaca atgaagggct tgtcttttta ttcccagatc cattcgcccg ccatacatat
    25381 catcaccgag cagggcacag ccaattgcgg aaaaatgaac tcttatttga tgtgtccttc
    25441 ctgtatgcag ctggatatca actaacgcga tttctgttag tcgcttctct atccagtact
    25501 cagtctgtgc cgaacgtcct tcatcagaga ccattcgctt caatagcgaa gaataatctc
    25561 gggcgatcgg caaatcgata tgtccatgtg ccgataaatc tgaaagcctt ccactgacta
    25621 aggcctgata ttttttcaca aacttctttt cacgaagttg catatctaat tttgcgtgcg
    25681 caaatccatg ctttgcaaaa agcatcaagc cagatgtatc ccgatctagt cgcgtcacca
    25741 catggattac ttggttttcg taaccttgtt ttttataata agcctttaca cgattagcca
    25801 ttgtcccatt tggatggtat tgggcaggaa tagacgaaac gcctgctggt ttatttacta
    25861 ccagaacgtg ttcatcttca tacacgatat cgatcggtgt ttcatccaaa agtacggttt
    25921 catgttctcc ttcagcagga atcacaatgg ttaccttatc atccttagct agagaaaaca
    25981 agacattttc tacttgatca ttaactttga tttgaccgcc ttgaaatttt attttcgcta
    26041 acagaccctt tgagatccct ttttctttta aaaaatattt tacttgctga gaatgatctt
    26101 tctcataatc ccatgtaaac tgcatatcaa tcctcactaa taaaggcatc tttcacacga
    26161 tgccaaaaat gcatatgtcg ataagaagca aaatggatcc gttcttctgc tattcgataa
    26221 taaattgagc ggatatttgc ttttgcgaca ttcaattgat caaccgttac aagataatct
    26281 tctgtatttt ccaattttat ttctagccat tcatcatggg caatcacgat cggagaaccc
    26341 aaagtacgaa acactcgatt attcagtgaa gcaatctctg ccaactgaaa ggcattgata
    26401 ctaggatgga tcacagcacc gccgacactt ttattatatg ctgtcgaacc agtaggcgta
    26461 gaaatcgtca atccatctcc tctaaaactt tcaaacagct cgtttttgat gtatacatcg
    26521 gctaccatcg tacgattggc ccgtttaatc gttgattcat tcagtgctaa aaaatgctgg
    26581 tccggtgttt catccaaata actgatccga acatccagca agggataact aacactttgt
    26641 tcccggttcg ttcgtaagct gtctactagt tcttccagct cgtaatcccg ccaatccgtg
    26701 taaaacccta aatgacctgt atgcacgccc aagaaacgca catcattcag acaatgactg
    26761 tagtgatgga acgccgacaa taatgtgccg tctccgccga ttgagatgac caattctggc
    26821 tcatgatcat ctcgttgaat ccctgcttgt tctaaaagtg cgttcaaacg ttctgtcact
    26881 tctatagtct ttgcttcttt attatgaacg atcgctactt tcatcccctg cctcctctct
    26941 ttcgctttct ttcttcaaaa gcgttcgata gtagacatca tctgattttc ctcttccatg
    27001 ggagaataac cgctgtgctt cttggatttc ttcacggata ctggacatct cttcatccaa
    27061 ctgataggca gcttctgccg cacgctgaag tcgttcactc atttcttctg gaaaaacgcc
    27121 ttgatattta taattcagcg aatgctcaat cgttgcccag aaattcatcg caagagtccg
    27181 aatctggatt tccgccaaaa ttttcttctc accgctgatc agctgtacag gatactcgat
    27241 caccagatga taagaacggt agccacttgc ttttttattt gtgatgtaat ctcgttcttg
    27301 gagaactttc atgtcttttc ttttacggat gatctcaaca acttgatgga tatcttctac
    27361 aaactgacac atgatcctta acccggcaat atcagacatt tcttcttcta aacgtcccat
    27421 tggaatatgc cgtaattgtg attttgttac aatactatcg actggcttga ctctcccagt
    27481 gacaaattca atcgggacat gtcgattttg ttcacggaac tgtttgcgga tcccccgcag
    27541 tttcactttc aattctgata cagtttgttc atatggtgct aaaaatgctt cccaatctcg
    27601 ttccatagct gatacctcta cttcattaac attcattgtt tattctacca tatatgcaaa
    27661 gttttttcgt actcttgatt tatgcattga ccaaaaaaag aaaattaggc aaaatagaca
    27721 aaaaggagtc gatcaaatga cacaaatgct tgaaatcgaa tataaatcta tgctgacaaa
    27781 gcaagagtac gagatattca tcgctcacta tcaattaaca gataaagatt tccgtgtaca
    27841 gactaatatt tatttcgata ccgttgatga acagctgaag aaacaaaatt gtggcctacg
    27901 gatccgtttc gttggtcatc aagctgaata tacattaaaa acacctgctg aaaaagggcg
    27961 tctcgaaaca acggatacct ttataacaga agaagcagaa gcatttatct tcgaaaaacg
    28021 tctgcctcgt tcaggcgcag tttttcaaaa actttctgat ttgaatatcg atcctgcttc
    28081 attaatccaa accggaaagc ttacaacaaa acgagctgaa ttccctattg aagaaggact
    28141 tttagctatt gatgaaagct ggggagacaa tctacacgat tttgaactgg aactagaggt
    28201 aggggatgca tctgtgggaa aaattgcttt tataaatttt ttaaaacgtt tttctttacc
    28261 ttatcgtcct gctaagaaca agatccaacg tatgcttgaa gctaaaaatt agaaaccttt
    28321 cattttcaca aggcacttga gttcattttt ttactttttt ctgttaagtt ataggatgtg
    28381 aaagaatcta gtcactagtt gtatagaatc tattttgggg gagattcata tgatcgaaat
    28441 ctatttattt gttaatcctt taggggaata ctgtttcgaa atggaacaac agttattaca
    28501 atttatcgaa gaagagtacg ggacaccatc aaaagaaaag atgcaatttc gctttcttcc
    28561 tttggtcaat ttgcagacaa ttggggatgt catgcaacaa aaaggaattt ctcagaacaa
    28621 tcttgaggaa cgtaatcact tattctcaat gacttattct gcagcattgg actgcaaagc
    28681 ggcgcagttt caaggaaaga aaaaaggccg ccgttttttg atcaaattgc aagaagcagt
    28741 cggctgtaat gacataccat attctcaaga acttgctgaa tccatatttg aagaaatcgg
    28801 cggcgatttg aatatgttta aagaagatcg tcagtctgac ttcgttaaag aagtattctt
    28861 ttctgatcaa aaaattgctc gggaaatggg catcacaaaa cacccttctg cagtcgttta
    28921 caattatgcc tgcgaccgtg attttggtgt tttagtagaa gtaaaaggta caagtagcct
    28981 ttggagaatc acagagctgt gtaaaacaac agataactca tatcaagttt ttaatggtga
    29041 acatttacat acaaatgatt ctcagttcca ttcaagaact agccatttac acttgctttc
    29101 taatt
//
LOCUS       DAXQKX010000031        28591 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.031, whole genome shotgun sequence.
ACCESSION   DAXQKX010000031 DAXQKX010000000
VERSION     DAXQKX010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28591
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.031"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..385
                     /locus_tag="ACF3MF_001541"
     CDS             <1..385
                     /locus_tag="ACF3MF_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFE3927537.1"
                     /translation="LKPEGRKAVDIENSINEWLQSVLKNLFKSITFDCGKEFSNWKSI
                     SNTNDIDIYFADPGTPSQRGLNEHSNGLLRKDGLPKEMDFHQVNQGFISSVASKRNHI
                     PRKSLNYQTPLEVFLSYVNGKFCLA"
     gene            complement(690..1056)
                     /gene="ssrA"
                     /locus_tag="ACF3MF_001542"
     tmRNA           complement(690..1056)
                     /gene="ssrA"
                     /locus_tag="ACF3MF_001542"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1227..2000)
                     /locus_tag="ACF3MF_001543"
     CDS             complement(1227..2000)
                     /locus_tag="ACF3MF_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFE3927538.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMDNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            2144..2494
                     /locus_tag="ACF3MF_001544"
     CDS             2144..2494
                     /locus_tag="ACF3MF_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HFE3927539.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2475..3191
                     /locus_tag="ACF3MF_001545"
     CDS             2475..3191
                     /locus_tag="ACF3MF_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HFE3927540.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAAVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            3191..4639
                     /locus_tag="ACF3MF_001546"
     CDS             3191..4639
                     /locus_tag="ACF3MF_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFE3927541.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4709..5218)
                     /locus_tag="ACF3MF_001547"
     CDS             complement(4709..5218)
                     /locus_tag="ACF3MF_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927542.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(5208..5933)
                     /locus_tag="ACF3MF_001548"
     CDS             complement(5208..5933)
                     /locus_tag="ACF3MF_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927543.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHSQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWRLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            complement(6156..8276)
                     /locus_tag="ACF3MF_001549"
     CDS             complement(6156..8276)
                     /locus_tag="ACF3MF_001549"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFE3927544.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLAKGKNVIYIHLESFQQFLIDYKLTDENG
                     LQLEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHKG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            8506..9684
                     /locus_tag="ACF3MF_001550"
     CDS             8506..9684
                     /locus_tag="ACF3MF_001550"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HFE3927545.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIVGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            9700..10458
                     /gene="aroD"
                     /locus_tag="ACF3MF_001551"
     CDS             9700..10458
                     /gene="aroD"
                     /locus_tag="ACF3MF_001551"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HFE3927546.1"
                     /translation="MVWVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLAGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            10481..10966
                     /gene="ybaK"
                     /locus_tag="ACF3MF_001552"
     CDS             10481..10966
                     /gene="ybaK"
                     /locus_tag="ACF3MF_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_process: GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HFE3927547.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSHIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(11037..12290)
                     /locus_tag="ACF3MF_001553"
     CDS             complement(11037..12290)
                     /locus_tag="ACF3MF_001553"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFE3927548.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            12407..13756
                     /gene="gdhA"
                     /locus_tag="ACF3MF_001554"
     CDS             12407..13756
                     /gene="gdhA"
                     /locus_tag="ACF3MF_001554"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HFE3927549.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNAQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            13868..15214
                     /locus_tag="ACF3MF_001555"
     CDS             13868..15214
                     /locus_tag="ACF3MF_001555"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HFE3927550.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(15522..15908)
                     /locus_tag="ACF3MF_001556"
     CDS             complement(15522..15908)
                     /locus_tag="ACF3MF_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFE3927551.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYTEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
     gene            complement(16176..16325)
                     /locus_tag="ACF3MF_001557"
     CDS             complement(16176..16325)
                     /locus_tag="ACF3MF_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927552.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            16787..16999
                     /locus_tag="ACF3MF_001558"
     CDS             16787..16999
                     /locus_tag="ACF3MF_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927553.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPTELVS"
     gene            complement(17277..19076)
                     /locus_tag="ACF3MF_001559"
     CDS             complement(17277..19076)
                     /locus_tag="ACF3MF_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HFE3927554.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRSFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(19200..19796)
                     /locus_tag="ACF3MF_001560"
     CDS             complement(19200..19796)
                     /locus_tag="ACF3MF_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFE3927555.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
     gene            20146..20490
                     /locus_tag="ACF3MF_001561"
     CDS             20146..20490
                     /locus_tag="ACF3MF_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HFE3927556.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVEWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            20491..20910
                     /locus_tag="ACF3MF_001562"
     CDS             20491..20910
                     /locus_tag="ACF3MF_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HFE3927557.1"
                     /translation="MMTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVTFEPGCRNHWHVHTDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(21002..21352)
                     /locus_tag="ACF3MF_001563"
     CDS             complement(21002..21352)
                     /locus_tag="ACF3MF_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927558.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(21318..22649)
                     /locus_tag="ACF3MF_001564"
     CDS             complement(21318..22649)
                     /locus_tag="ACF3MF_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HFE3927559.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGVFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSVLSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGILLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLSGIREIFDSSGKLTT
                     DFIANSGIGATLINMGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            22904..23470
                     /locus_tag="ACF3MF_001565"
     CDS             22904..23470
                     /locus_tag="ACF3MF_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFE3927560.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            23615..23702
                     /locus_tag="ACF3MF_001566"
     tRNA            23615..23702
                     /locus_tag="ACF3MF_001566"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:23647..23649,aa:Ser,seq:cga)
     gene            complement(23809..24957)
                     /locus_tag="ACF3MF_001567"
     CDS             complement(23809..24957)
                     /locus_tag="ACF3MF_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFE3927561.1"
                     /translation="MATFEQYKKKNGEKLWKFQTYLGVDPLTGKQVRTTRRGFKTKKE
                     AQLALTKLQLEYESNGLNKSKELTFQEVYDLWIVNYEQTVKESSFVKTKEQFANHILP
                     AFGALKINKISIDIAQKFANEKVKRFVLYREFINNASRICDYAIKLGYLQDNPFKKIT
                     VPKRKVSVHEENTLNFFNKEELEIFLKSVEKKKDIRMYSFFRTLAFTGMRVGELLALT
                     WKDIDFNDNYIKINKTLARGKNRRLYVEQPKTKNSKRDIPVDDETMNILKKWRLEQRK
                     WLLTLGINTLSKNQLVFSNQKNEYLQLSKPRKWLEVIIKQNNLKRITIHGLRHTHASL
                     LLEAGANIKDVQERLGHSSIQITMDLYIHITDKRKEKTAAQFAKYIGI"
     gene            complement(25065..25700)
                     /locus_tag="ACF3MF_001568"
     CDS             complement(25065..25700)
                     /locus_tag="ACF3MF_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HFE3927562.1"
                     /translation="MAKKVMGQDGKMYKVKKPFYKRVWFWVLIVLLFFGIGGALSGGE
                     NKDSATATSTSTNKETTKETTTKEEKTYKIGDDVAVGKMEYKVNSVEVVKQVGPSVLP
                     TNAKDTFLVVDLSVKNAGDKAVTVDSSFFKLKADGKTFEADSAASMSANQDENGNITN
                     SFFMESLNPDMQQTGKIVFDISEAQANAQNNVLQAQTGYFGTETVSIALHN"
     gene            complement(25782..26204)
                     /locus_tag="ACF3MF_001569"
     CDS             complement(25782..26204)
                     /locus_tag="ACF3MF_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HFE3927563.1"
                     /translation="MYLKLKEMLSEYNLKLIYMEMEEPGFYYPKPRIVFLNEKLHEDS
                     SEAFHLAHELGHFIASHFEYSALYDNSTTFHSKFETEADRIAIMILLNIFIENELTDE
                     SQFKLENFMEFYSINNKLRTECFNVCQSYFKKKYSYAQ"
     gene            complement(26222..26545)
                     /locus_tag="ACF3MF_001570"
     CDS             complement(26222..26545)
                     /locus_tag="ACF3MF_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFE3927564.1"
                     /translation="MTVFERIKFLAKKHSKTMKQVTIDLGYSENYFYSLKSGKQPSAE
                     KLTEIANYFNVSVDYLLGREKKETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKA
                     LEENE"
     gene            26837..27028
                     /locus_tag="ACF3MF_001571"
     CDS             26837..27028
                     /locus_tag="ACF3MF_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927565.1"
                     /translation="MSNIDNGREAIKEFMKANNISEYDLATAYGRSRTWIQRVLSGKD
                     KGPAVNAFILEVIRDHKIR"
     gene            27042..27302
                     /locus_tag="ACF3MF_001572"
     CDS             27042..27302
                     /locus_tag="ACF3MF_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFE3927566.1"
                     /translation="MEVILTPENEAALRSYIHEIITDEIAKARRDASVDKRVLKQIEI
                     AKYFGVSTATIRKWEDKGLPFGRIGDQKFYDKEKCRAWVLAQ"
     gene            27351..27533
                     /locus_tag="ACF3MF_001573"
     CDS             27351..27533
                     /locus_tag="ACF3MF_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927567.1"
                     /translation="MDKLNTTIVFSAPIIIYLLSVWGNIPALIGTIVYMVWIFIGLDE
                     AEYRAKKASREGLTKI"
     gene            complement(27539..28015)
                     /locus_tag="ACF3MF_001574"
     CDS             complement(27539..28015)
                     /locus_tag="ACF3MF_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927568.1"
                     /translation="MRKKLNYILTATLTIYIILFITLSFLSSIKKIPFITLNKNSILK
                     EFNNIDYIAFLKLFSVCVLISCVIIFIVAKTCWTMLNKNQRDVENIAIFLIKITSSIS
                     IIIPMTVTFSKEQFNVAATYLSFIALFSFVLPKRNKSNFDNKELDEVRNSSPKEQK"
     gene            28068..>28591
                     /locus_tag="ACF3MF_001575"
     CDS             28068..>28591
                     /locus_tag="ACF3MF_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HFE3927569.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFKKKHKHVLEAIESIKRSVENS
                     ANVEDGSNFGQMFVEGNEPDSYGRSRRVYFMNRDGFSLLAMGFTGSKAINFKLKFIEA
                     FNEMEDVIRKNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNM
                     KVMEVLGGKESRAY"
BASE COUNT         9625 a         4981 c         5441 g         8544 t
ORIGIN      
        1 cttgaaacca gaaggccgta aggcagttga tattgaaaat tcgattaatg aatggcttca
       61 atccgtactc aaaaatcttt tcaaatcaat tacctttgat tgtggaaaag aattctctaa
      121 ttggaaaagt attagtaata cgaatgatat tgatatttat ttcgcagacc caggaacgcc
      181 ttcccaacgg ggattaaatg aacattcaaa cggactcctc cgaaaagatg gactaccaaa
      241 agaaatggac ttccaccaag tcaatcaagg attcatctca tccgttgcgt ccaaaagaaa
      301 ccatatccct agaaaatcac taaattacca aacaccatta gaagtttttt tgagttacgt
      361 aaatggaaag ttttgtctcg cttaatttga caaataataa ttaaaaaaac ttatttgaag
      421 gaacatgctt aaaccataat tgtgtttttc cttccatcag cataaaagtt cacctcaaaa
      481 agagtgtacg aacaaaagtt ctttttgtaa accttaaaat agattttcct gaatacgtat
      541 tggggatttc taaatgtttg aatgtttttt tgaatgcaaa atcaatgcaa aaaattttgt
      601 atttctctac ttttctctcc ttgaccaaaa taaaaaaacg ttgatttaac aacgtttttc
      661 atacatgttt atctgtctca accatacata tatggagacg gcgggagtcg aacccgcgtc
      721 caaacacatc gccacttaaa aatctacgtt catagtcaac tcatttaagg attcacttta
      781 cagcttgccg agtgacaggc attctgtatc gctagtctga tgttctcttt ttcaacttac
      841 agacggaaag ttgaaacgta tcccactaaa gttaggaccc ttactcgagc acatgggcga
      901 tgccgagagg atctacgcta actgttttta ggcagctaaa gcgtaagagt tgttttcgtt
      961 tttagcagtt atatttaact gtaacgtttt tacgtagacg taacctacga aacgcaattc
     1021 aagctcgact gtgcctgtcg aatccgtaac gtccccgtta gctaacaagg gttacgtgta
     1081 tttttcatac aaaattagta tagcatatat tgggataaat tcaataaaaa agcgaatcat
     1141 atcccattat ttatataata actgcccctt tcttaagaaa aaataagcga ttttcttaag
     1201 aaaagaggta gcttcaaaaa aagatcttaa atcagatcaa aatacttcaa tgcgtggaca
     1261 attccgcctt ctgtattttt ctttgtgata aaggtagaaa gttcttttaa tccgtcatag
     1321 gcgttgtcca tagcgatttt gttgtcgcaa gcttccaaca aggcaaaatc attcggacca
     1381 tcgccaaatc caaaagtagg aactttttcc agctgaagtt ctttttgcag acgtttgaca
     1441 cctgcccctt ttgagattcc tttcttcact gtatcgatcg agtaaggacc attccgataa
     1501 aaagttagct caggaaaatg ttcgtgatag tattcgtcac ctgattgaga taagatcagc
     1561 aacatattta ctgtgttttc tttaaagcct aaaggatcaa tttccggaac atctgaatga
     1621 atgaagtcgt aagcattgat cattgtttgg ctatgaccgg tacaccagat tttctgatcg
     1681 ttatagtaag aaagttcatg accgttcaac tgtacatgat catacatttt ttgacattct
     1741 tctgaagaaa atgtttgaga atagatttct tcgccgtcta ctcgaatgaa agaaccattc
     1801 atggtgaccg cagaagtaat gcccgcatct tccatgatag agtggatttc tgcttctgta
     1861 cgtcctgtag cgatgacggg gagaacattg ttttctttta atgcgttcat agcttttgcc
     1921 acttcgggtg tgatttttga tttcgcatct agtaatgttc catcaagatc aaagaaagtg
     1981 attgcacgat aatttgacac aaataaaact ccttttttat tggaataagt ttatcttaac
     2041 aaagaatgaa caaaagacaa acctttcgtg aagaattcct gaacatattg gttcagtcaa
     2101 caatttagag tatactataa gaagagaatt taggagggaa agaatgattt ttttcagtat
     2161 tggtatctta ttcttaataa ttggcagtct ttttcggatt ctgccctcaa aaggaaatct
     2221 gcctttttat gggtatcatt cgcctcttgc cgcaaaaaca gacgctcatt ggcggctggc
     2281 tcaaaagaca agcggaaact ggttttttct tatgggctta ctgatggcat tgatcggcta
     2341 ttatttaaag acatctgggc atacgaatta ttttctgatt gaaatgcttc tgctagtatt
     2401 tccaattatg cctattttta ttatgacaga aaagaaatta cagaaatatg acctggaaac
     2461 tggagggaac gataatgaat attttaatga ttgaagataa tcaatctgtt tctgaaatga
     2521 tgcagatgtt tttcttaaat gaaggttggg aagcaacttt caagtatgat ggaaaagaag
     2581 ggctcgatgc ctttttagaa aacccacaac attgggatat gattacacta gacctgaatt
     2641 tgcccacact ggacggtatg ctagtaggaa gagagatccg caaagtttca agtactgtgc
     2701 cgattatcat gctgacagct agagattctg aaagcgatca ggtgatcggc ttagagatgg
     2761 gggcagatga ttatgtcaca aaacctttca gtcctctgac gcttattgct cgaatgaaag
     2821 ctttgcatcg ccgtagtgag ttggcagaag caagagaaga agcagcagtt tcagatgatc
     2881 attttgatat cgagactagt catttcaaga tgaatacgaa aacacgagaa gcgtatctgg
     2941 acaaccggcc aattgaagga ctgacgccta aagagttcga tctattgttt actttagcaa
     3001 aaaaaccacg tcaagtattc tctcgggagc agttgcttga attagtctgg gattatcagt
     3061 actttggtga tgaacggaca gtggacgccc atatcaagaa attacgacaa aaaatcgaaa
     3121 aggtcggacc acaagtcatc caaactgttt ggggagtcgg ctacaaattc gatgattctg
     3181 gtgttgccta atgcgttatt tgtatcagca actcttagct ttttgcggaa tggtcgcgtt
     3241 gatcttattg atcgttggag tttcttttac acaactgaca aaacaaacga ttgaagaaaa
     3301 caattaccag caactgtttg gatatgctga atcagttgaa aagacaacgc aaacctatgc
     3361 cgatacgctc ccgcagttta gtcaagatca ggcgtttcaa aatgcattgc tgctgacaga
     3421 gcaagtactg acagaacaaa atgtgaactt tatatttatc gataaaaacg aacgtgtcat
     3481 ttatccgact aatacagctt tactgaattt taccttaaca gctgatcaat ggaaaaatct
     3541 gaggaatgga cgtcaagaaa aattcacatc gaataaaaat attttaggac aagcacaggc
     3601 gacctcttac gcacttgtgc catttaattt gaatcatgaa ttctatggag cacttgtagt
     3661 tagtcaacct gcgcgaaata tcgataacag cgttcgtcca attacactga acctgttcaa
     3721 aggatttatt ttttccagta tcgttgcagt tattgccagc tatgcttttg cagcattcca
     3781 agttaagcgt atcaatcggt taaggaatgc gacgaaagaa gtgacgaatg gtaattttga
     3841 tgtacagctc cccgtacatg acaaagatga atttgatgag ttagcagatg atttcaataa
     3901 aatgacgaat tcattgaaag aatctcaagc agaaattgaa gaacaagaaa atcgtcgaag
     3961 acaatttatg gcagatgctt ctcacgagat gagaacacct cttacgacaa tcaacggact
     4021 tctggaaggg ttagaataca atgcaatccc tgaaaatcag cgagaaaacg cgattaaatt
     4081 gatgaaaaat gaaacagagc gtctgatccg tttggtgaat gaaaacttgg attatgaaaa
     4141 aatccgtacg aatcaaatca gtatggtcat taaaaaattc aatggaacag aaacattgaa
     4201 aaatattgtt gcacagttag aagctaaagc agaagcagca ggagatacat tgacattgaa
     4261 agccgttgat gatattgatg tttacgctga ttatgaccga tttgtccaaa tcatggtcaa
     4321 tattattcaa aacgcgatac agtttactga aaacggccaa atcacgatta ctttagaaaa
     4381 aggctatctt gaaacgatca tcacgattga agatacggga attggaatgt ctgaacaaca
     4441 aatgaaaagt atctgggatc gttattataa agtagatcct tcaagaaaaa atacaaaata
     4501 tggtgaatca ggattaggtt taccaatcgt gcagcaactt gtacgcttgc ataaaggaaa
     4561 attagaagta gaaagcgaac taggaaaagg aacaaaattc gctgttcgtt tgcctgacgt
     4621 agaaatcaaa aaagagtaaa aaacaagcgg tataaaagat catgaatcga tcttctatac
     4681 cgcttgtttt tactataaaa tgattgattt agcccgcggg ctctaaacga tcaatataag
     4741 gactttgagc aatagtagca tcatgagtaa agagtaagat accttgattt tcttcatgag
     4801 ctaaataaga aagcaagtgg agtagctctt ggatctccaa tacactaagt tcatcaaatg
     4861 tatcttcaat aacaatattg tttcgcttgg aaagcaaggc atgaagtaat tgcagcttta
     4921 ctttttcaaa agacgtcaac tcagctgccg cacaattaag caaggaagga gagatatcaa
     4981 gtttttcttg ataggccaaa cgatcttgtt tgatttcttt ttccggtaca tccaacagga
     5041 catggtcttt aagattcaga taaggaaaca tcggccaatt tttttggatg atcgcaaaat
     5101 tatccagttt tgcaacaaga acctcttttt tcaagtgctc caatatttta tgctgttttt
     5161 cgagaggaca caaaataacg gtcaagtgtt cagcatgaat caaatattca ggtttcatta
     5221 cgtccaggcc tcctactttg caaatgatgg ataaaaaaag tgaaagggaa tagactaaga
     5281 atgagacagc atccactgag cccaataaga gtttgggcaa atcccttaag tatatctgtg
     5341 aaaaaaagat cattttggaa atcgatggta aaaaaagtct gttgatccat cggaattgta
     5401 agtccgctta ccgaagtcaa gatatcacgg atatctggca gttcagtagt ctttaagaca
     5461 agaaaattga tcctttgaag aagcgcttca taaactgact ggaagctgac gatccacaat
     5521 aaaaccaaga tacaacaaag aaagagagga aagaacagct gccagaaaat aaaaaggaat
     5581 aatttggttt tagaaagacc agtcaggcgc caattgatca attcctgctt gttttgcctg
     5641 actgaatagt aaaagaaaaa gataaaaagg aaggcaaata gaaaaaataa actgaatatg
     5701 ccttttatat aaaatcggct agctaattct aaagccggaa gaagctctgt agatgcagaa
     5761 gcgccaataa atgaaagccg atcttggact tgattggcta aagccgattg cgaatggtaa
     5821 agagtcaggc atgctatcaa taaaaaagca gaaaagcttg aaaataaaca atagagtatt
     5881 gtctgctttt tgtaataaat taatcgagca gtagcatagc ggattatttt catacttttc
     5941 acctctataa aaagtataga aaatgaatat gaataaagta tgaaattcct ttagtgaaat
     6001 cacgaattaa aaccagaaaa tattttgtaa aaagcaagag gttgtgaaga agctgcccta
     6061 ttctattacc gtagatgcaa gcttttgaac actgtttatt cgaaaagagg agcagcgaca
     6121 ataattttgt cgctgctcct tttaaattta ttttatcatt cggaagaact tgtggtcgtt
     6181 ccgtgaagtt cttggtacgt ttgcgtttta taaagatcaa cagttgattg tcccttgtgt
     6241 tcactaaaga cactagttga cttgtcacca agagattttt cagcttcttt taatttctct
     6301 aagccattct tgtagtcata atcactggta tcaattgggt ctaatccact attcgtatag
     6361 aaccgaagaa gatcaccatt attgatttgg tcagaaacag ctaactgttt atcaactttt
     6421 tctttcagtg aatcaatttc attctgtact tcctcagtag gttcagtaat agcttcacca
     6481 gtttcgttac tatagatcgt accaccgtag taagtatatt ttggtgtaac aaaatcacca
     6541 tcacggaaag aaacaagctg ttcatgatct ttcgagaata gatcttgtcc taactgaata
     6601 taattttttg tatctacacc tagtaagtga agtaatgtag gcaaggcatc aacttgtccg
     6661 ccgtaagtgt gattgattcc gccctgtgtt tgtccaggga tatggatcat ataagggaca
     6721 cgctgcattt gtgcattgtc gtagtttgtc caagtagaac ttgtttttcc aactaattca
     6781 gctagatttt tatttcttga attcgagaca ccgtaatggt caccgtaaag gacgatgact
     6841 gaattatcat acaagccgct ttctttcaaa taattgaaga attcttgtac ggcggtatct
     6901 aaataattgg ctgtcgcaaa gtaaccgttg atcgtttcat catttgtatt ggctaacggg
     6961 aatcctgctt cgtcattggt gaattttgaa taaggataat ggttagatac agcaatgaat
     7021 tttgaataaa atggttgttg cagacgttcc aagtattgta cggattgttg gaaaaatggt
     7081 ttatcatgca acccgtattg gaacgaattg tcatcattaa catcataata agaagaatca
     7141 aagaaataat catatcctaa attcttgtat gtctcgtttc gattccagaa tgtaccagcg
     7201 ttcccatgga ataccgcact agtgtaacct tgtgtttgac ttaaaatatc aggtgcagct
     7261 tggaaagtat tttttccgcc taattgtgtg aacaaggagc cttgattcaa gccaaacaat
     7321 gaattttcca tcagcgtttc cgcatcgctt gtttttcctg cttttacttg atggaaaaag
     7381 ttgtcaaaac tgaacgtgct gttgctgtgg taaagactat tgatgaaagg tgtaacttca
     7441 agctggagac cattctcatc tgtcaattta taatcgatca ggaattgctg gaagctttct
     7501 aaatggatat aaatcacatt ttttccttta gcgagcccga acaaatcatc atttggtgct
     7561 gcataatgtt cttttacata attttctact tctttcatat cattgggact tgcttctgcc
     7621 cgcacttggt ttgtctggta agtttgaaca ccgtcataaa ccatgaaagc attcaagcca
     7681 agatatttga ccaaataatc acgagagaat gttcgagtca gcaattctgg acgatcagct
     7741 tccgccataa aaagatttcc tgagaaaatc ataactgcta atgtagagat cgcaaaagcc
     7801 attcttgctc ggatcgggcg agggtccaac ttgatttttt ttgcaatcag cagaacagtc
     7861 aagataataa aatcgatcca atagatcaca tcatatgggc gaaacagtcg aatggcactt
     7921 tctcccagac cactcgctac tttcccagca cctaaaatcg tgttgatcgt aatgaagtcc
     7981 gtgaattctc gataataagt gacattcgaa aaaacaagca atgtcaaaag aaaataaatg
     8041 accatcatcg tgatataagc aactctaggg cgtctgatat aaagagcaat tccaagtaat
     8101 aacaatgtag ttgcaatagg gttgataaac aagataaagt attgaatgcc actttcgatt
     8161 ccgagatgga aatcaactaa ataggcaaaa atcgttttca accaaagtaa aacaactagt
     8221 aaagaaaaaa atccgagcct cttattcaaa aaggcaggtg tttttataca tttcaagata
     8281 atcttccttt ctgcacttct taatcacaga agtgtcatga aaccatgtta cacagctcac
     8341 ttattctcat ttattttact agtatgacaa tatagtgtca attgaaacca gaagtttatg
     8401 ctgtttcatt aaggttttct ttaagcttca tgaaaaaatg agcagtaaga caagtcctat
     8461 gttttttgtt atacttggga agagaaagct aaagcaggtg aaggaatgaa agtaaaagta
     8521 aaaaaaagag caagcaatcg attgaaaaaa ggatatccac tgatccaaaa agaagacctt
     8581 gctcatcccc aaaaagaaac cacgcaatgg gtggaattag ttgattcgca aaaccaattt
     8641 atcgcaaaag gatatctagg aaagcagaat aagggaatcg gttgggtatt gagccagcag
     8701 aacatcccat ttgatcaatc tttttttgaa gaattttttg tgaagtcaaa agaaaaaaga
     8761 actttctttt tttcagatga ttctactacc gcttttcgta tattcaatgg agaaggagac
     8821 gggatcggcg gtctgattgt tgattattat gcaggttatg ctgttttttc ttggtataac
     8881 gaaacgttat atgcacatcg tgaattattg attcaagctt ttcgtgaaat ctacccggaa
     8941 atcgtaggag gctatgagaa aattcgattt gaatcagtaa atctgcctga gagccagttc
     9001 atttacggaa aagaggcacc ggaacccttg atcgtaaaag aaaacggagt aaaatttgcc
     9061 gtttatttaa atgaaggatt aatgactggg atctttttag accaaaaaga agtacgggga
     9121 tcattagcag aaggtttcgc ttctgggaaa acagttttga acatgtttag ttataccggc
     9181 gccttttctg ttgctgccgc aatgggaggg gcaatcgaaa caacaagtgt cgatctagca
     9241 aaacgcagtt taaaaaaaac acaggaacag tttgaagtga atggtttgga tgtcgatcag
     9301 caaaaaatca ttgttatgga cgtattcgag tatttcaaat acgccaaaag aaaacaattt
     9361 ttatatgaca tgattgtatt ggatccacca agttttgcca gaaataagaa aaaagtcttt
     9421 cgcgtagcaa aagattatgg ggaactggtc aaggatagtc tggatatttt agcagaagac
     9481 gggatactta ttgcgtctac aaatgctgcg aatgtctcga tagaacaatt ccaaacaatg
     9541 attgaagagg aattccatgc caaaaatgtt tcttttgaac aacttgcttt atatcgtctg
     9601 ccaaaagatt tccagacgac ggataccttt ttagaaggca attatctgaa agtgtttgtt
     9661 tatcaaatta aaaataacca ttagaaggag cgatgcagaa tggtttgggt aaagggattg
     9721 aatataggaa gcggtagacc aaagatttgt gcgcctctta tcggggccgt ccgagaggaa
     9781 gtattacgtg aagcagttct tgcacgtgaa gcaggggccg atttagtcga atggcgagtc
     9841 gatcattatc gtgaagtttt ttcttttgat gaagtagcag aaacattggt tcttatccat
     9901 gagatgcttg atggactgcc gttattattt acgtttcgta ccttagctga aggcggagaa
     9961 caagacatat cgatccgtca gtatcgcgac ctttatgaac atgtgataca cacaggatta
    10021 gtagatatgg tcgatatcga gttgttcaaa gtagaaagtc taggaaaaag actgatagag
    10081 gaaatcaagt ctttaaacat tcctttaatt atcagtagtc atgattttaa agaaacacca
    10141 gcagaccctg tcttgcttta ccgattgaat gttatggaac attttggagc cgatatcgga
    10201 aaactggcag taactcccaa taatgaacga gatgttttgc ggttgatgga gttgactaga
    10261 cgggcaaatg cttttgtctc catgcctatt attacgatgt ccatgggaaa tcttggtaaa
    10321 atttctcgtc tggctggcgg aacgacgggt tccgttatga catttggttc cttaagcagc
    10381 gattctactt ctgctccagg acaattaccg gtcaaagcat tgaagcaaat tattcaatta
    10441 ttaaatgaac cgttgtagaa caagtttgag gtgatatttt ttggcaaaga aaaaaatagt
    10501 aaaaacgaat gcaatccgta tggtcgaaca aaaaaagatt ccctatacag agcacgaata
    10561 tgagtgggac gaaagccacc taagtgcgtc atcggtcgct gaacagcttc cagaaagcca
    10621 atctcatata tttaaaacac tggttgctgt gggcaatgtg acggggcctc ttgttgctgt
    10681 gataccggga gaagccgaat tgaatctaaa aaaattagca aaagtttcag ggaataaaaa
    10741 agtagaaatg ctccatttaa aagatttgga agcaacgacc ggatacatac gtggtggctg
    10801 ctcgcctata ggtatgaaaa aactatttcc tacttattta gatcaaattg cagaaagcta
    10861 tgaacaaatc attgtctcgg ctggcagaag agggctacag atggagttag cacctcaaga
    10921 tatctgtgca ttaacgagcg gacaatttgc agatataaaa caataaatca tacgtataaa
    10981 agaaagaagg aggccgggat gttgtttgtc cagtctcctt ctttcttttt tatacattat
    11041 gctctttgcc cggcattcat tcctgctaca tgccctgtag cgaaagccgc tgtgatatta
    11101 aagccgccag tataaccatt gacatccagt aattctcccg caaaatacag accatcaatg
    11161 attttactct ccaatgtttt aggataaatt tcctttagag aaacccctcc gccagttaca
    11221 aatgatttct caataggaaa agttttgttg attgatagct taaactcttt gcatagttga
    11281 acaaaatctt gaatttgttt ttgagaggct tgttgtcctg tcagatgatc catttcaagc
    11341 cgctcaagaa agaaaactaa caatcgctca ggcaatatac catgccaagc attgaccaag
    11401 ttctttttgg ttgctttact tttttctgtc aatatatgaa taagctcttg tttggtttgt
    11461 gtagggaaac aatccagaga aagtgtcact ggttctcccg ttttctctaa ttctttattg
    11521 acaaaacttg aacaacgcag tgcagccgga ccagaaatac cgaaatgggt gaaaagtaaa
    11581 tccatcgtat gttcagtcaa tacacgacct tttttattta aaacgcgtaa agtgatgtct
    11641 tgtaaagaaa gcccttgaag tgttttctcc tgaatatacg gttcatccga tatcaagggg
    11701 gactctgtcg cataaagagg cgtcaccgtg tgacccactc gcttcacgat cttgtaccca
    11761 tctccagtag aaccagtaga tggataagtc cgtccaccag ttgttaagat aatggcagga
    11821 gcatggaact cttcgaattc cgtgcgtata ccgtaaattt tatgttcttt gtggatcaat
    11881 ttctctactc gagtagagaa tagaagcgtc acatctagtt ctttcagacg attgagcaat
    11941 gcttcgataa tcgtttttga tttatttgtt acaggaaaca tccgtccatg atcctcttct
    12001 tttaaatgta cgccttgtga ttcaaagaag ttcatgatat cgaaattatt ccattgcgca
    12061 aacgtactat ataaaaactt tccatttcca ggaatatgtg caatcaaatc atcaacagga
    12121 cgattgttcg taacattgca ccgaccacca cctgtcatca gtagtttttt tcctgctttt
    12181 ttgttttttt cgatcaagag tacgcgtgcg ccttgttcag ctgcactgat cgctgccatc
    12241 atcccgcttg ttccagcgcc gactacgatc acatcataca gtttttccat tccctcacct
    12301 caaggaaagt gtagcatatc tgaagaaaga aaacagaaaa aaatgttttg agccaaaaga
    12361 gaaaatgagc taaaatgagg gaagataagc aaaggagcgt ggaacgatga caaacgcaac
    12421 agaatatgtt caagcaattc aagaaaagct acatcaaaag gatcaagggc aagaagaatt
    12481 tttacaagca atcgatgaat tcatgcccac ggttatgtct tttttggaca ctcatcccga
    12541 atatatcgaa aagaatatct tagaactttt aacggaacca gaaagagtta ttcaatttcg
    12601 agtgccttgg caagatgatg aaggaaactg gcgagtaaat agagggtacc gtatccaata
    12661 caactcagct atcggccctt ataaaggtgg attgcgcttc catcctagtg tcaatctaag
    12721 tatcttgaaa tttttggctt ttgaacagat tttcaagaat agtttaaccg gtctgccaat
    12781 cggtggagga aaaggcggaa gtgacttcga tcctaaagga aaatctgata atgagatcat
    12841 gcgtttttgt caaagtttca tgctggaatt gtcaaaacat atcggcccat cgattgatgt
    12901 tcctgcggga gatatcggtg taggagctag agaaatcggc tatttgttcg gcgaatataa
    12961 acgattgaaa aaatatgata ctggtgtgtt gacaggtaaa cctttggatt tttggggaag
    13021 taagatacgt acggaagcta ctggttatgg attagtgtat tatgtcaaac atctattgaa
    13081 cgaagaaaaa gattcattta atcaaaaaac agtttttgtt tccggaagcg ggaatgtagc
    13141 catttatgca atcgaaaaag tgcaagagct aggcgggaaa gttgttacat gttcagattc
    13201 tagcgggtac atctatgatc cagaaggaat agatgtgaaa ctattgaaag aagtcaaaga
    13261 aatcaataga caacgtttga cggaatacgc aaaccaacgt ccttctgcta tttatcatgc
    13321 tggagaatct gtttggacat tgaaagaaaa agcggatatc gctttgccat gtgctactca
    13381 aaatgaaata gacgaaagct tggccgaaat cttagtagaa aatgggatca aaatcgtagc
    13441 agaaggcgct aatatgccat gtacagtaaa agctgtttct gttcttcatg aagcaggcgt
    13501 gtggtattgt ccaggaaaag ctgctaatgc tggaggagta gcagtatctg ctttagaaat
    13561 gagtcagaac gcccagcgat tgacttggga aagagagcaa gtggatgagc agctggatca
    13621 aatcatggaa acgatttacc atacgtgtcg ccaaacagca gccgagtacg gcgacgaaaa
    13681 aaatctgctt cttggagcaa atgttgctgg atttgaaaaa gttgccaaag caatggcagc
    13741 agaaggttta gtttgaaaaa tgaaactttc ttggaaatat tgtcagcatt ttgtttattt
    13801 gcttgaaaaa taataaaaaa aaacgtaaag tattacctgt agagtaaacc tataaggagg
    13861 agaacaaatg gcacacattc attttgacta ttcaaaagta gcaccgtttg tcaacgaaca
    13921 agagttaggg tacatgcaaa gccaagtaac agcagcccac aacgaattac gggaaggtac
    13981 tggcgcagga agcgacttcc gcggctggat cgatttacca acgaactatg acaaagaaga
    14041 atttgcacgt atcaaagaag cagctaaaaa aatccaatct gattctgaag tattagttgt
    14101 tatcggtatc ggtggttctt atttaggcgc tcgtgcagcg atcgacttct tgaatcacac
    14161 attcttcaat ttattagata gcaacacaag aaaagcacca caaatcttct ttgccggaaa
    14221 ttcaatcagc tcaacatata ttgctgactt gatcgaagta atcggtgatc gcgacttttc
    14281 agtaaacgtt atttcaaaat ctggaacaac tactgaacca gcgattgcgt tccgtgtatt
    14341 caaagagctt cttgttaaga aatatggaca agaagaagca aacaaacgta tctacgctac
    14401 aacagataaa gcaaaaggtg cagttaaagt agaagcagat gcagaaggtt gggaaacttt
    14461 cgtgattcct gatgacatcg gcggacgttt ctctgtatta actgctgttg gtttgttacc
    14521 aatcgctgtt agtggtgcag atatcgatgc attgatgcaa ggtgccgctg atgcaagcaa
    14581 agcatactca agcgacaaac tagaagaaaa cgaagcttac caatacgcag caatgcgcaa
    14641 cattctttac cgtaaaggca aagtaactga gttgttgatc aactatgaac caggaatgca
    14701 atacttctca gaatggtgga aacaattgta tggtgaatct gaaggaaaag accaaaaagg
    14761 catctatcct tcaagcgcaa acttctcaac tgatttgcac tctttaggac aattcatcca
    14821 agaaggacgt cgcaatattt ttgaaacagt tgtgaaggtt gaaaaacctc gtaaatcaat
    14881 cacaattcct gaacaagcag aagatttaga cggtctaggc tacttgcaag gaaaagaagt
    14941 ggacttcgta aatacaaaag catttgaagg aacattgctt gctcatacag acggtgacgt
    15001 gcctaacttg ctagtcaaaa ttccagaaat ggatgcttat acattgggtt atacaatgta
    15061 cttctttgaa attgctgtag gtatttcagg ttacttgaat ggaatcaacc cattcgacca
    15121 accaggtgta gaagcttaca agaaaaacat gttcgcactt ctaggcaaac cgggctttga
    15181 agatcttgct aaagaattga acgaacgcct gtaagataag ggtttttcgc tagatttaaa
    15241 taatcagtga tagaaacatg ttcgctttaa aatgaaaact ggtacccatt taggtactca
    15301 aacatactgc atcgtttatt cagaataagg ggctgtgaca agacgtttgt cacagtccct
    15361 tgtttgtata gaaatcgatt gattgccttg ctctttagtt tgttttagga ctttaagaac
    15421 agtgaggctg acttcgaagg ttaattctgt ttttttgttt tctagaatca gtaagcaaaa
    15481 aagcactcac ttcgagtgct tttttgcgat atattcttag cttaagatag gcctaatttt
    15541 tcttttacag atgagggtac cttatcgctg gtaattactt ttttctctat gatccgcttt
    15601 tcgcttgctt tcaactgcaa gatcgttcct tcggtgtaag cagaaccatt ggcagagtca
    15661 ccagaagtaa tgacatcgaa atctaactgt cttttttcac cgttttcagc ataagcatct
    15721 acgttgtatt taaaacctct tccaattact tccccattat ctgctttgat atcagtttct
    15781 gcaggcattg gagctttgac taccgcataa taatctttac ctacataagt agactgatag
    15841 tagtcccaac ctttccatcc tataaaagca atcaatatga taacgatcaa ccctaaaatt
    15901 tttttcatga aagatctcct tttttatttt tattatatta aatattatac agataataac
    15961 ggaatattat catcgaaaca gctaacaaaa ttgtcataaa aaacgagatg gttgatatta
    16021 gaacttgtgt ttttgtttag gtctagagat aaagagagac aatttccaaa tatatgtaat
    16081 gaatacaaaa agacgtttgt cgcggattac cgttacaaac gtcttttatt gattttccga
    16141 gatctcatca gtcgccattt ggaatggttc actccttatc tagattcgtt taatgctcgg
    16201 actgcttgtt cgattgtaat accaaacgca acgttatttt cgttttgtgc atcaatcgcc
    16261 ataaaacggt tagaagttgt atcaaaagct acgcggtatt gcatatttgt ttttgtaaac
    16321 gtcataaaat tcatctcctt tgtaatgtaa tttagttctt gaaagtttcc tttaaacttt
    16381 cgaacttata ccaagtttag catcgtacgt tttttgatgc aattaaaaag catttatcat
    16441 tttccttatt tattttttct taaatggttt agctattttc ttttaatccg ataagtagcc
    16501 caatcatcaa ggttacaaat actattgctt gaatataaat catatgctca cctctttata
    16561 aataacttag caatataaag aaaaaaacgc acgaacaaca taggaatata aacaaacgtt
    16621 tttgtcacaa cgtctaagat cgtgttaaaa aatagttatc taaaaagcag aaagatactc
    16681 aaaataaaaa ataaaaaaat gaataaaaac gttttcaaat acaaggtaat ttgttattat
    16741 aaaataaaga aaaaacaaaa taaaaataaa gaaaagaggg aatgaaatgg taaaagcaga
    16801 agtaggaaga tcttatatat gcaaaccgat cggagtatct catgaactaa tcggctgtat
    16861 tgaacgtaca tatatcaaca cggctgtcgt gtatgttgaa agttatgacc aacgagacta
    16921 tcaacttatc aatgaaagca agtatcgcat gctcgtaaaa ttctgtgata ttagcgcacc
    16981 tactgaattg gtttcttaaa cagtattttt gagaattcgc aagaactccc ttataatata
    17041 aataaagaca gaagggagcg agaagatatg ccaaaaagaa aaagttcagg gaaaatggga
    17101 attattcttg cagtgatctc tgcaattcct gctattttag ctattgttcg tgcgatgaag
    17161 gaatcaagag aaagttaagc acacattatg agcgtcaaac aaaaaacgca tatacctgcg
    17221 gtggcaggtt atgcgttttt tgttgtataa agactttttt cattaacgat ttttgattag
    17281 ccgactccca aaacaaaatt tagcagttta tctgaataag tgatttcttc atctgtttgt
    17341 ttcacacttt catttagtag tcccatctca tcggttatga taccatccac accataaaac
    17401 atcatgcgac tcatggcatc tgaatcgttg attgtccata catatacttc ttttccgtct
    17461 tggtgggcag aattaatgaa gttacggttg atcgtactat attccattgt cagaaaatca
    17521 gcaggcgtca cagggggccc aacaatattg aaaggtaaga tgtagcccac ataaaagttt
    17581 ggttctgctt cttttaaatc tgaaacggtt tggtacgtca aactttgcaa aatatgatgg
    17641 ttctctaaga taactttgcg gtatttatgg acaaatcgtt cgacaaggtc atccgaatct
    17701 tttttagagg tcttgatctc aataagtaat ttttggttta gcttatgtgc tttttccaaa
    17761 taagaatcaa aagaacaaac aggggcttgc actccgtttt cagtaactgt aagatttgtc
    17821 aattctttca atgtaagatc ctgtggtgtt ccatttaccc ctgttaagtg acgaagattt
    17881 gcatcatgca tcactacgaa atgaccatct tttgtttcct gaacatccat ctctacataa
    17941 tcaggatgat agtctctgct tgttttttca agtgcttcta aagtattttg cgccccattt
    18001 tgggtactca cacctctgtg agagacagtc actggttttg tctgaacagc tgaagtcaga
    18061 taatccatat tgtaaagaca gacgccaata ccgaaaaaaa ctgcaaaaag agtcaaacca
    18121 gtgtttttca gcgcagagaa acgcaagttg ggggcttgtg ggataaacca cttagggatc
    18181 tcaggcaaga agccttcgtc atccatgaaa tcaacaatga tataaaaaat ccctacggta
    18241 gacatcacga tattgaataa taaaatccct tgtaaaagcg tcatagcaaa cacagcgctg
    18301 atcaatgcat agtctgggaa aaattgttca accatacttt gtgccaaaat aacaacgata
    18361 tatcctaaag aagaaaggag taaaatcgta ccgccaatca caataaattg gcccgtgatg
    18421 gccaaaagac gcgatttggt caatgaccag ctttcccgaa tggctgctcg aaaagaacga
    18481 tctcgtagaa tcatttccgg taaagcaaaa atcagtcgaa tcccaatata gccaaggaaa
    18541 atataaacga gtaaaaagga actgacgatg atccaacgat tagcaaaaat aaaatccata
    18601 atgaaagcgg ggatttttat ttttgacagt agatcagaat taaaacttaa tccgctgatc
    18661 ggtagaatca ataaaaaata agcaaggaaa aacaaaaaag taatgggtct cactttcttc
    18721 agctgaagta tcgtcaagtg taagagttgc ttcaaagaga ttggttcttt ctttttaata
    18781 aaaaaaacac tcatcaaaag aaaagtaaat tcgaaataaa ctaacagtaa aatcgtcatc
    18841 aaaactacga ttaacgagag tagaacccca ggatgttgag aaaaaattga aggaatattg
    18901 tcataagaca aatagtcaat tgcccctcgg tgtaaaataa aacgggtcgt actgctcaat
    18961 aagggtaaac aaataaataa aataaagcca tgcatcagca agacatcacg gaaataagct
    19021 tgtgttcctt ttaaaaagtc ccaagcatta cctaagctac gtttcaaata attcatccta
    19081 tcacctgctc ttcacattgt agcgcaaatc taatgaaaaa ggaaagggtg cagtgtgttt
    19141 tgcagaccct ttcccagatt taacattgtc aatcaatgac taattttaca aaataaatat
    19201 tatccaagaa gaccacttag atattgacct ccataaatca aggccatact atataagaaa
    19261 atcgacagtg gtttagcaat caaaatgatt agtgtatatc gtttcactga catgtttgtc
    19321 aatccagcca tcaaacataa cgcatcgtca ggagcaactg gaagaaaaat agctagagca
    19381 aacagcttct caaaacggtt ttgattatcc agccagccaa tatatttgtt atatgtctta
    19441 tcgctaatca tggaaagtat gaatggcttt ccataacgac gccctagcag aaaaatgata
    19501 atcgaaccaa tgcagattcc aatatagtta tagataaatc cagcataagg gccaaatatc
    19561 aggacaccag ctgcagtact gatccctcca ggaatgattg gaataactac ttgcaggatt
    19621 tggatgaaga caaaaataat cggtcctaaa atgatggaat cacctactaa tcctcttaac
    19681 gcattcaaat ctttgaaaac acctaaatta ataaaataaa tcgtcagcgc gattgatagg
    19741 cctaatccga taatggatat gaaatttatc agttttcgag aggcagcaat attcattatt
    19801 catcaactcc ttagaggttc tttgttaact atactttact agaaaagcaa ctaactgcgc
    19861 cattttttga tatgacagaa aacaaacaat tttgtaagtt catcataagt ataaaagatt
    19921 gatctcaaaa aaacatccaa ctaaagactt atttaataac ttgttttttt taaaataaaa
    19981 aaagcgttag caactatgct taaaaagcat atcgactgaa taaactaagc attggacagg
    20041 ctgaaagact acatttaaaa tgaaatgcga agaaacaata gaaaataaag ttgccttaga
    20101 accatagttg aatcacctaa cagtcgtgaa gggagaataa gagaaatggc agaaaaacaa
    20161 accgcaggac gagatcaatt aggagatttt gcaccaaaat ttgcagaatt aaatgatgat
    20221 gttttatttg gacaagtatg gtccagagaa gaattatctg ctcatcagcg tagtatcatc
    20281 accatatctg cattaatttc aggaggaaat tttgaacaat tgccagctca tctgaagatt
    20341 ggcaagcaaa atggcattac tagtgaagaa atagcagaaa tcattaccca tttagctttt
    20401 tatgtagaat ggccaaaagc ttggtcagct tttagtttag caaaagaaat ctatttagaa
    20461 gaaaatagcg aagataagaa agaggcgtaa atgatgacaa aacacgaaga aatacacaat
    20521 ggcgtgattt ttccagcagg tgaaaaaaac gaagcttacg ctcaagtatt taccgggcaa
    20581 agctatctga atatgttagt gaatgatccc gaagtttctg ttggtgtagg taatgtaact
    20641 tttgaaccag gttgtcgcaa tcactggcat gtccatacag acggctatca aatcttactt
    20701 gtgaccggag gagaaggctg gtatcaggaa gaaggaaagc cagcaagacg attaatggct
    20761 ggagatgtcg tcgtaacgca caaagggatt aaacattggc atggtgcgac aaaagacagt
    20821 tggtttgaac atttggcgat cactgctggt aattcagagt ttttagaacc tgtaacagat
    20881 gaagtgtatg aaggattgga aaatcaataa tgtcaagctt gaacagctcc tgaaagtaga
    20941 ttttaatcga actttcagga gctgcttttt tgattcagtc ttttataaat agaaaatagg
    21001 gttaataata ggaatgagaa gcacgtcgaa agatcttaat attgataatc ggctgggcat
    21061 acatgatttc cacgtcatca atcaaactac ctaacagatg ataatcttcc cgatcatgtc
    21121 ggggattacc taatagttct tgatagtaga tttccatact agggtcccga ggattgttca
    21181 gcaaatcagc aagtacatct aaatcttctg gctgagtttc tgccgtaccc tgtatctcta
    21241 tgaaaagccc ttcctcagca aattctactc caatacgtat ttcagttatt tcatgggaat
    21301 ataaataagt aagaagctca tcgatgattc tttttgataa ttctttttcc aagtgtcttt
    21361 ttttcctttc tgacagcggt aaagttatct agtatcggta caaggatacc tgcaacgaaa
    21421 ccagttgaaa aaccactgtt atatagattt agtcctccgt gcaaagtgct gacgttatgg
    21481 acaagagcaa tatgtagcac accagctatt acaccgtaaa aactgccgta aaaaccgctt
    21541 atgggcgcaa gacctgtccc aaacacagct gcaacaagca tgccagtact ggtgatctca
    21601 tgaaaagttc caaacaaaga agcaataaat attccgacta gtatcggaaa actgtttttt
    21661 aaatgacaac caaaagcact gaaacccacc gcagataaaa tagcaccgat gacaggtcca
    21721 tttaactgac cgccaaccag caaaacataa gaagacagca tcagaccaac taagcccatg
    21781 ttgatcaaag tagcaccaat accagaatta gcaatgaaat cagttgtcaa ttttccagat
    21841 gaatcgaaaa tttctcgaat ccccgaaagc cgaaaggaat tataatagaa accaattccg
    21901 actgtcagcg aaaaaaagcc aaaaataatc caaatgagag gaaagtgata ttcattgaaa
    21961 accaatgtat tttcgacgat tgaatagctg aataacctca aaacagcagt aaaagtcatc
    22021 gcaatcaacc cagaggtgaa tccaatatta taaagtgtga atccacgatg gaaaactaaa
    22081 gtttgagcag ctaagggcgg aagaagtata ccaattgcta tgccagctaa attccccaat
    22141 aaaataccta tcagtaaagg aaaacgcata ccaaaagtga tataactaac gaccggtgat
    22201 aatacgctac caaacagtcc gatcatgatg tactgagaaa aaggtttatt gacaaataca
    22261 gcgtatagat acacacctaa aatgattgag atagaattat aaaggttttt gccaaaaaaa
    22321 gagaaaccgg taactgttag aatcgaagca aataagggac cgtttaaaat caccttgtgc
    22381 cgataagcta aaagcacaga aagtaaggtc aaaatcccta catttatgaa tgcgcttccg
    22441 aaaacaccta aagcaaaata atctgtcaaa agattgcttg gcgaggtaag aatagttagc
    22501 aatccactcc aattatcagt aggagtatta gaaagcaagc caataaaaag aaaaaaaaca
    22561 cctgtaaaac caagataaaa atactttctt ttctgtgaaa cgattcgttt ttgaggatga
    22621 atataaataa cgtcagtttc gttttccatt acacaccttc tttttcattt tctttaacta
    22681 taacttgaaa tgaaagattt ggacaactat catttaggtc aaaactaaaa atgtaaggga
    22741 acccattgaa tttaaccaaa tttttttaat tttgcaaaaa aaagttaaag aagactgaaa
    22801 aaaatttaaa atataacgtt ttgagtaaaa tgtttgcaaa aaatgctaaa aatagggtac
    22861 aataaaacaa catatactgc agtaaagaag tgggggagtt ttaatgagaa gaaaagtcta
    22921 taccaaggat caaattctaa aagctgctta tgatgttgtt gcaaaggaag ggtttaaagg
    22981 atttactgcg agaaatattg ctaaaaagat ggggatttcg acacagccga tttatctgga
    23041 attcaaaaac atggaagatt taaaaaatac gttgctggat tctatctttg aacaactaaa
    23101 agaagatgtt ttccctattg aacgtactgg tgataaaatc attgatctcg gtttgaacta
    23161 tatctacttt gcaaaaaagc atcatagtct ttacatggca ttgtacattg atgaacatgg
    23221 ggacggaaag aaaatgcatg atttttcata caattatttc cgtgaaatag ttaaagaaga
    23281 tgaaagatac aatcaattat cggatgaata tgtcgatgct ctgcatactg gtacatgggt
    23341 agcagtgact ggcttagcgt cattgatgtc atcaaacatc atgcatccaa cagaagaaca
    23401 aatcattgca ctgatcaaac ggacaattga ctcgatttta gcattagata atcctgaaat
    23461 aatcagatag tgttctatca gtatgaattt gatcggtaag tccgttggct gcaaactgtc
    23521 aatggacttt tttgctaaaa aaagcgattt ctgttattta tctattagaa ataggcttga
    23581 catttcgtga aaaaagttta aaaatagtac ttacggaagg ttggcagagt ggtaatgcac
    23641 cggactcgaa atccggcgaa ccggctaata ccggcgcgca ggttcaaatc ctgtaccttc
    23701 cttatataac attttataat agaggcgaaa acattgatat acaggcattt gcttgcaatg
    23761 ttttcgcctc tgtttttttg tttgaatacg tctttgaata cgttctgctt aaataccgat
    23821 atattttgcg aattgcgctg ctgttttttc ttttcgtttg tctgtaatgt ggatatataa
    23881 atccatagtg atttgaatag acgagtggcc taaacgttct tgtacgtcct taatatttgc
    23941 accagcttct aaaagtaaac tagcatgtgt atgtctaaga ccatgaatag taatacgttt
    24001 aagattattt tgtttgataa tcacttctaa ccatttacga ggcttagata attggagata
    24061 ttcgtttttc tggttagaaa ataccagttg atttttgctt aacgtattaa ttcccaatgt
    24121 taacaaccat tttctttgtt ctaatcgcca tttcttcaag atgttcatag tttcatcatc
    24181 gactggtata tctcgcttag aatttttggt tttaggttgc tctacataaa ggcgtctatt
    24241 ttttcctctg gcgagagttt tatttatctt gatataatta tcgttaaaat caatgtcttt
    24301 ccatgtgaga gctaagagct cgcctacgcg catccctgtg aaggctagtg tccgaaaaaa
    24361 agaatacata cgaatatctt ttttcttttc tactgatttc aaaaagattt ctagttcttc
    24421 tttattaaaa aagtttaaag tattttcttc atgaacagag acctttcttt ttggaactgt
    24481 gattttttta aaaggattat cttgtagata tcctaattta atagcataat cacatatacg
    24541 cgaagcatta ttgatgaatt ctctatacaa cacaaatctt tttacctttt cattagcgaa
    24601 cttttgagct atatcaatcg atattttgtt gattttaaga gcaccaaatg ctggtaatat
    24661 atgattcgca aactgttctt ttgttttaac gaaagaactt tcttttactg tctgctcata
    24721 atttacaatc catagatcgt atacttcttg aaaagttaac tctttagact tatttagacc
    24781 attactttcg tattccaatt gtaatttggt cagcgctaat tgagcttctt tttttgtttt
    24841 aaaacctctt cgtgtagttc tcacttgttt gccagtcaag ggatctactc ccaaataagt
    24901 ttgaaacttc cacaattttt caccgttttt ctttttgtat tgttcgaatg ttgccatttt
    24961 tttcgtcctt tcgctcgggt aagtgttcgg actaaaatag ctggcatcac ctccttagtt
    25021 atacgatctt actttggacg gtgggtgtgt tttttttata ctaattagtt atgaagagca
    25081 attgaaactg tctctgttcc aaagtaacct gtttgtgctt gcaatacatt attttgtgca
    25141 tttgcttggg cttcagagat atcaaaaact attttaccag tttgttgcat atcaggattt
    25201 aagctttcca taaagaaaga gttagtgata ttaccatttt catcttgatt tgccgacata
    25261 gatgcagccg aatcagcttc gaaagttttt ccatctgctt ttaatttgaa gaatgagcta
    25321 tcaacagtca cagccttatc acctgcattt tttacagata agtcaactac taagaaagtg
    25381 tcttttgcgt tagtaggaag tacagatggg ccaacttgtt ttactacttc aacggagttt
    25441 actttgtatt ccattttccc tacagcaacg tcatcaccga ttttataagt cttttcttct
    25501 tttgttgtag tttcttttgt agtttcttta ttagtacttg ttgatgttgc agtagctgaa
    25561 tctttgtttt caccgccact tagagcacca ccaataccaa aaaacaaaag tactattaat
    25621 acccaaaacc atacccgttt ataaaacggt tttttaacct tatacatttt cccatcttga
    25681 cccataactt tttttgccat ttaaatattc ctcatttctt gttataatat atttgtgatc
    25741 tcagaaatga ggtatgagtc cgtgttgcag cacgggcttt tttactgtgc ataagagtat
    25801 tttttcttga aataagactg gcaaacatta aaacattctg ttcttaactt attattgata
    25861 gaatagaact ccataaaatt ttccaatttg aactgagatt catctgttaa ttcattctca
    25921 ataaagatat taagtagaat cataatagcg attctatcag cttcagtttc gaattttgaa
    25981 tgaaaagttg tagagttatc gtacaatgct gaatattcaa aatgtgaagc aatgaaatga
    26041 ccgagctcgt gggctaaatg aaaagcttca gaactgtctt cgtgtagttt ttcattcaaa
    26101 aatactattc ttggttttgg ataataaaaa cctggttctt ccatttccat atagattaac
    26161 tttaaattat actcactcag catttctttc aactttaaat acatacaacc catcactcca
    26221 actattcatt ttcttctaaa gctttagcaa ttgcaatcgc tttacgcatt gtctccttag
    26281 agatttcttt tccgtcaaaa gagaatacag tatcgtcttc tgataaatcc acatgtttag
    26341 gggtctcttt tttctctctt cctagtagat agtctacaga gacattgaaa taattagcaa
    26401 tttcagtaag cttttcagcg gatggttgtt ttccactttt taaactatag aaatagtttt
    26461 cactgtatcc taaatcaatt gttacttgtt tcattgtttt tgaatgtttt tttgcaagaa
    26521 attttatccg ctcaaatact gtcataccag cattctcctt ttttctttac aaaaaaccaa
    26581 taaaaaagtg tagttttgtg ttgacctaaa caacactata gtgtatattg gttttgtaag
    26641 ttaattggat agaaaaaaag caaagtaaaa acacacctta tagcattaag tttggcgacc
    26701 gagtgcgata aaaaggcttg ttatatgctt atttaactat ggctatatac tacactatag
    26761 tatggtttgc agtcaactaa aaatatactt ttctatccaa ttttctttct aaataaaaag
    26821 aaaggaagtg tgtgaagtga gtaatatcga taatgggcgg gaagccatca aagagtttat
    26881 gaaagcaaat aatatttcag aatacgattt ggccactgca tatggtagat cgagaacttg
    26941 gattcagcgt gttttaagtg gaaaagataa aggtccagct gttaacgcct ttattctgga
    27001 agttattcgc gatcataaaa ttcgatagga ggttcaggat tatggaagta atcttaacgc
    27061 ctgaaaatga ggcagcactt cgtagctaca ttcatgaaat cataactgat gaaattgcaa
    27121 aagcaagaag agatgcctca gttgataaac gtgtattaaa gcaaatagag atagcgaaat
    27181 acttcggagt atcaactgca actattcgta agtgggaaga taaaggactt ccattcggac
    27241 gtataggcga tcaaaaattt tacgacaaag aaaaatgtag agcatgggtt ctagcacaat
    27301 aaaatatcgg gtaagtgttc ggaaataatg acagtaaaga agggggattt atggacaaac
    27361 taaatacaac aatcgtattc agtgcaccaa tcattattta tctgctgagt gtctggggaa
    27421 atatcccagc attaatcggc acgatcgttt acatggtttg gattttcatt gggcttgatg
    27481 aagctgagta cagagcgaaa aaagccagtc gggagggact gactaaaata tgattttttt
    27541 atttttgttc ctttgggctg ctattgcgta cttcatccag ctccttgttg tcaaagttgc
    27601 tcttatttct tttaggaaga acaaaagaaa atagcgctat aaatgaaaga taagtagccg
    27661 ctacattaaa ctgttctttt gaaaaagtta cagtcatcgg aatgataatt gatattgagg
    27721 aagtaatctt aattaaaaat atagcaatat tttcaacatc gcgttggttt ttatttaaca
    27781 ttgtccaaca tgttttagca acaataaaaa taattacaca tgatattagc acacagactg
    27841 aaaaaagttt tagaaatgcg atgtagtcaa tgttattgaa ctccttcaaa atactatttt
    27901 tattcaatgt aataaaagga atttttttaa ttgaagacag gaaagataag gtaataaaca
    27961 gaattatata tatggttaaa gtcgcagtaa gaatgtaatt gagctttttc ctcatagaat
    28021 cacctcactt tctaacgaaa attataccaa aaaggagaga agaaataatg caagaattag
    28081 taattttgaa aaataaagaa gctgtaacta cgagcttaca agtggcagaa agtttcaaaa
    28141 agaaacataa gcatgtacta gaagcaattg aatcaataaa aagatcggtc gaaaattcgg
    28201 ccaatgttga agatgggtcc aattttggac agatgtttgt ggaagggaac gagccagact
    28261 catacggaag aagtcggaga gtttatttca tgaatagaga cggattttcc ttgctagcta
    28321 tgggattcac tggaagtaaa gcaataaatt tcaaactaaa atttattgaa gctttcaacg
    28381 aaatggaaga tgttattcgg aagaatactg ttcctcaaac aattgaagac atgatgatct
    28441 atcaattaga agaaatgaaa gatgttaaaa aagatgtttc catgcttaaa gatactatgc
    28501 gaattagcgg acaacaagag tttgaaatta agcaaaaagg aaatatgaaa gttatggaag
    28561 ttctaggggg aaaagaaagc cgagcttatg a
//
LOCUS       DAXQKX010000032        28033 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.032, whole genome shotgun sequence.
ACCESSION   DAXQKX010000032 DAXQKX010000000
VERSION     DAXQKX010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28033
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.032"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            185..1183
                     /locus_tag="ACF3MF_001576"
     CDS             185..1183
                     /locus_tag="ACF3MF_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFE3927570.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            1295..1804
                     /locus_tag="ACF3MF_001577"
     CDS             1295..1804
                     /locus_tag="ACF3MF_001577"
                     /EC_number="3.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HFE3927571.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(1834..2493)
                     /locus_tag="ACF3MF_001578"
     CDS             complement(1834..2493)
                     /locus_tag="ACF3MF_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HFE3927572.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(2495..3259)
                     /locus_tag="ACF3MF_001579"
     CDS             complement(2495..3259)
                     /locus_tag="ACF3MF_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HFE3927573.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(3267..3944)
                     /locus_tag="ACF3MF_001580"
     CDS             complement(3267..3944)
                     /locus_tag="ACF3MF_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HFE3927574.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(3981..5366)
                     /locus_tag="ACF3MF_001581"
     CDS             complement(3981..5366)
                     /locus_tag="ACF3MF_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HFE3927575.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(5576..5660)
                     /gene="ffs"
                     /locus_tag="ACF3MF_001582"
     ncRNA           complement(5576..5660)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACF3MF_001582"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5683..6198)
                     /gene="tadA"
                     /locus_tag="ACF3MF_001583"
     CDS             complement(5683..6198)
                     /gene="tadA"
                     /locus_tag="ACF3MF_001583"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HFE3927576.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            6305..7162
                     /locus_tag="ACF3MF_001584"
     CDS             6305..7162
                     /locus_tag="ACF3MF_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3927577.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(7243..7578)
                     /locus_tag="ACF3MF_001585"
     CDS             complement(7243..7578)
                     /locus_tag="ACF3MF_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927578.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(7645..9015)
                     /locus_tag="ACF3MF_001586"
     CDS             complement(7645..9015)
                     /locus_tag="ACF3MF_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HFE3927579.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(9093..9629)
                     /locus_tag="ACF3MF_001587"
     CDS             complement(9093..9629)
                     /locus_tag="ACF3MF_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFE3927580.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            9938..11419
                     /locus_tag="ACF3MF_001588"
     CDS             9938..11419
                     /locus_tag="ACF3MF_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3927581.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            complement(11522..12229)
                     /locus_tag="ACF3MF_001589"
     CDS             complement(11522..12229)
                     /locus_tag="ACF3MF_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HFE3927582.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(12308..12646)
                     /locus_tag="ACF3MF_001590"
     CDS             complement(12308..12646)
                     /locus_tag="ACF3MF_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HFE3927583.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            complement(12757..13719)
                     /locus_tag="ACF3MF_001591"
     CDS             complement(12757..13719)
                     /locus_tag="ACF3MF_001591"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HFE3927584.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            complement(13734..15065)
                     /locus_tag="ACF3MF_001592"
     CDS             complement(13734..15065)
                     /locus_tag="ACF3MF_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DRTGG domain-containing protein"
                     /protein_id="HFE3927585.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            complement(15073..15753)
                     /locus_tag="ACF3MF_001593"
     CDS             complement(15073..15753)
                     /locus_tag="ACF3MF_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HFE3927586.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            complement(15972..16451)
                     /locus_tag="ACF3MF_001594"
     CDS             complement(15972..16451)
                     /locus_tag="ACF3MF_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HFE3927587.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            complement(16578..18257)
                     /locus_tag="ACF3MF_001595"
     CDS             complement(16578..18257)
                     /locus_tag="ACF3MF_001595"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HFE3927588.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            18805..20307
                     /locus_tag="ACF3MF_001596"
     CDS             18805..20307
                     /locus_tag="ACF3MF_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFE3927589.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            20320..20982
                     /locus_tag="ACF3MF_001597"
     CDS             20320..20982
                     /locus_tag="ACF3MF_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3927590.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(21083..21286)
                     /locus_tag="ACF3MF_001598"
     CDS             complement(21083..21286)
                     /locus_tag="ACF3MF_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFE3927591.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(21397..22581)
                     /gene="iadA"
                     /locus_tag="ACF3MF_001599"
     CDS             complement(21397..22581)
                     /gene="iadA"
                     /locus_tag="ACF3MF_001599"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008798 - beta-aspartyl-peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HFE3927592.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            complement(22738..24477)
                     /gene="yfcC"
                     /locus_tag="ACF3MF_001600"
     CDS             complement(22738..24477)
                     /gene="yfcC"
                     /locus_tag="ACF3MF_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HFE3927593.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            complement(25250..25864)
                     /locus_tag="ACF3MF_001601"
     CDS             complement(25250..25864)
                     /locus_tag="ACF3MF_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFE3927594.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(26470..26847)
                     /locus_tag="ACF3MF_001602"
     CDS             complement(26470..26847)
                     /locus_tag="ACF3MF_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927595.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(27147..28028)
                     /gene="galU"
                     /locus_tag="ACF3MF_001603"
     CDS             complement(27147..28028)
                     /gene="galU"
                     /locus_tag="ACF3MF_001603"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFE3927596.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
BASE COUNT         8325 a         5875 c         4686 g         9147 t
ORIGIN      
        1 atttgcatac ttcataataa taataacata atacctaacc tctcgtaaaa atactagatt
       61 tgttttcttt tatttttcat cactagatac attctataac ttaccgtttc gatttcgaat
      121 tcaaacattt ttgagaagca ttctcaatta aattctgcta tagtgtgaaa agggaggaat
      181 ttttatggaa atctatgaca ttacaatcat cggtgcaggt cctgtaggga tgtttgccgc
      241 tttttacgca ggaatgcgcc aagctaaaac aaaaatcatt gacagtctac ctcaacttgg
      301 tggtcaatta gcaactttgt atcccgaaaa atatatttac gatattcctg ggtatccagc
      361 aataaaagca agtgaattaa tcgatcaatt agaaaaacaa ttaactactt ttaaccatac
      421 attccattta aaagaagaag ttctctcgct tactcgtgaa gacgaagtta tcgagattac
      481 tacaaataaa ggcatccatt attccaaagc agtcatttta gctttaggaa atggttcatt
      541 ccagccaaga aaattgaatt tagataatgc tgaatcattt gaaaaccacg gattggatta
      601 tttcgtgaat gatttgatga agtatgctgg aaaaaaagtc gctattgctg gaggtggtga
      661 ttctgctatc gattggacgt tgatgttaga gcctattgca agcgaagttt acttgattca
      721 tcgtcgcccg gaatttcgtg cgcacgaaca tagtgtatca cgcttgaaat cttcatctgt
      781 caacttgctt actccctatc tcatcgatgg attatcaggc aataatgggg aactgacaga
      841 tatccggtta aaaaaagtga aaagtgacga gacgattgat ttgatgattg attctctgat
      901 cgtcaattat ggattctctt ctaatttaga acatctttct tcttggggac ttgatagtac
      961 cagaaatgcc attactgtaa aatcagatat gtctacttct attccaggcg tttatgcagc
     1021 tggtgacatc tgtacctatg aaggaaaagt gaaactgatt gctactgggc tcggtgaagc
     1081 acctactgca gtgaacaacg ctttacacta tattaatcca aaggaacgaa ctcagcctgg
     1141 tcacagcaca agcttatacg ataaaaatct tcgtcctagt tgatttttta tatctctttg
     1201 catttcaagt taaacccgaa agcagtttct tgcatttttt tcatgttccg ttaacatgaa
     1261 atagagaaag aaaaaataaa gggggagcaa taatatggtc gtcaaaactg agactttaga
     1321 agaaaaggca agagaactat tgaaggaacg tggcgtaact gtagaagata tcgcacaact
     1381 tgtcatgttt ttacaaaaag actatatttc tgatttgact ttggcggatt gtactgaaag
     1441 tgtcaacagc gtgctaacaa agcgtgaagt acataacgcc attatcactg gaatccaatt
     1501 agatatatta gcagaaaaga aaaaattgat gagtccgttg caacatatta tcgaagatga
     1561 cgaaggcctt tacggtatcg atgagatcct agccttgtca atcgtgaatg tttacggtac
     1621 gatcggcttt acgaattatg gttatatcga caaggtgaaa cctggtattt taaaagaact
     1681 aaacagccac gatggcgttc atgtccatac cttcttagat gatatcgtcg gagcgatcgc
     1741 cgctgctgct gccagtcgat tagcacacaa agaaccagaa aaaagaagtc gccttactca
     1801 ataattcaac aaaaaaagaa agaaaacgtc tatttagacg agttctttct tttttgtttg
     1861 tttcaagcta ttttttccta agaaaagaaa aacagcaaaa aataattcta ataatacaaa
     1921 aaataagata aagctatgca tgaaaaattc ttctggaagt acattgatga ttggatcagt
     1981 aacgggatcg aataaccagt catcgttgtt gaaaaacgtt tcatgaaaaa ggataaaaaa
     2041 gcgatcaaat cctatcatca tgaaaaaacc gaaaacaact ggcagtaaca tgccgatttg
     2101 aaacggacga atcaaccgcc aaagccgatc attcttttgc aaatatttga taaacaaaat
     2161 actcgggatc aaagtgatga aaaacacagc ataatccact aaaaacaaaa ttttcacttc
     2221 ataaaagtga tgggctccgc tagcagaaac tgggaaatct ggcaagctga ggatggtttt
     2281 gaagggatta ttgagataat tcattaggtg atcaaaattt ttcagtaacg tctcttgatc
     2341 taaagaagta taatccaaaa tttgcaaatg tccgatatca aatacgtata gtggtcgaaa
     2401 gttgatcgtc acaccaactg ccagactgat cagtgtcaga aataggctga acaatccagc
     2461 atattccatc cactgccatc tcgaattttt catattagaa gctccattca tccagtgatt
     2521 gtttcacata ggtagctggg ataggcaacc caggtacatc ttcttctttt gtaaaacctg
     2581 ataaaacgag caaagtatct atattattgc gtatcccagc ttggatatct gtttcatagt
     2641 tatctccaac catgattact tcttcttttt gcagccctaa tacttcaacg gctttatcca
     2701 taatgatggc ttctggtttt ccgatgtaga tcggcggcgt ttgggttgct gtctctacaa
     2761 aagagatgac tgaccctgct ccaggaagaa ggccgcgttc agtaggtata ttcttatctg
     2821 ggttcgttcc aatgaaagta gcaccttttt gaatagcaag tgttgcttta actacttttt
     2881 cataggtcag ataattatct aagcctacca ctacatagtc aggagcctct tcttcccatg
     2941 taaatccggc agctaaaatc aagtcaatca atcctgcttc tccgataaca tagacttttt
     3001 tcccttttcc atctgctttc ataaaatcga ttgttgccaa agtagctgtg tagactgtct
     3061 ctggagctac atgaatgtca aactcatctg ctagacgatt agctactgtt tctggtgact
     3121 tagtcgtgtt attggtaaca aacaagaaag gtaattttct tttttgcaat tcttccacaa
     3181 atcgtttacc ggccggtatg ggttgtgtcc cacgataaat cgttccgtct aaatcaatta
     3241 aatatccttt atagtccatt catccactac tcttcccttt ttctgatcgt aaatgctgtt
     3301 tttgtttttt ctacttgttt aggttgttct tgttttttta ctttttcaga ggtttttgct
     3361 gactctgttt ttcgattttt aataaccggt tttttgcgat tagatgcgac tggtcctttt
     3421 ttctcatcga tatacgcacg attatggttt tttttctttt ttcggcgctg agttgtcttt
     3481 tcttttttac cgccgattct ctcgatgaca aaatacgcac aaccaaaatt gcaatattcg
     3541 taaagatagt cttccaagga atcgattcgc tgatctggat gcgcccgtcg attatccgct
     3601 tggaaaaatc cttttaggcg tagttgttca taaccccaat ctcctacgat ataatcatat
     3661 cgggctagta catcactgta acgttctcca agcttttctg cattaaatcc ttcacgataa
     3721 tcggacacaa gccgataatg tctttcacct atcaaaaaat tactgtcatc taacagtgtc
     3781 actagctcgc ctttgacttt ttctgcttta ggctcctcaa cgatttcttc caaagcagct
     3841 gtcagttctt cggtgactgt tgtttcctgt tcagctgatg attttttctt agcaatttct
     3901 gttttatgct caacgttctg ctgttcattt tgttttgcag acatgcgttc accacctatc
     3961 ttttttatta taccttgttt ttatttgatt gggtagtgag ctttcaagta atctcctacc
     4021 acacttcgga taaattcagg gaacaaaaat tcattttttc cagcaatctc aatcgttgga
     4081 aaaaatggaa caaacatcaa atgatctacg gtagtaaaag tataattttt attcagatcg
     4141 attggcttgt tcttccaaaa gacttgatgg ttaatagaat catatgtgat tccattatag
     4201 accatctgcc caaaaatctt accgcgaaat cccattccct tcataggata gttacgtaaa
     4261 aagttacgat ttttttctat ttctaaaact aagcggatca gatcatttcc acccaatgtg
     4321 acatttaaca agtgcatcgg atgcggcaac gcagtgtgaa gctgatcctg attgacccgc
     4381 ccttttggaa tttcagttaa aaacagacca ctgtttaata ttgctgcttc cgtctttcct
     4441 cgttctttca ccgcctcaaa ggctacttgg ataaacgaat gctcattgaa gatatctaga
     4501 ctcagagaaa atggcaaatc tgctacttct ttttctttta ataattcatg cccacgttct
     4561 agataactat ttatttcttg ttcatcttct gtaaaagctg tcattgtttc ggtagggatg
     4621 gctttggctg aatgcttaag gatttttttc tcttcatcga tggttaaatg gacttcaccg
     4681 acatactgcc cgtactttcc agcggctgct atttggacat cattgattac gtgaccttct
     4741 ctgaataaat gatgggtgtg cgatcctaaa ataacatcaa ttgctggtat ttcttttgca
     4801 atttggaaat catcctgaat cccgagatga ctcatcaaaa ctaaaacatc cacttgtgaa
     4861 cgtaaatctt cgactaattc tggcaaaata tcataaggat tccgtatgtc ccagccattc
     4921 ggattataag taagcggaaa tggagcagta aatgcaatta gtccgatttt cgtctggtgt
     4981 ttcgttgtaa tgattttata tggtttcgtc catgccggtg gctggagcgt atttttatcg
     5041 aataagttat ccaggatgat atcaaactca gcatgatcgt ataaatgatt caactcttct
     5101 ttggaatttc ctacgccttc attgtttcct atcgtcgctg catcataacc aacttcattc
     5161 atcagcaaga tattttcctg tccattcgtt gcttctgaca atggatgcca acgatccaca
     5221 aaatcaccta gatctactgc aatcgttgtc gttttttctt tcttttcgtt ttctcgttta
     5281 cgttgatcca aaaaccttct gatccttggc caattttcta aatgagaatg cagatcattc
     5341 gtatgtaaaa tcactatttt ttccatgtac cctctcgcct ctctttatct ttatcatacc
     5401 ataggcagct ttttcttcca ttgaaacaag ctctatttca gagtttttcc tgccttgaag
     5461 caaattgtat aagtacaata ttcgataaat cagtctggct aaaaaatcag gaacattcat
     5521 ttttacagta ctataaaaat aaaaaaaaca gacccgaaag tctgttgtcg tttcattata
     5581 atcagacaca tggcggaacc tgcttagtgc tgcttccttc cagacctgac acgcttcaca
     5641 agcccaccat tgtcctagcc tttcggcaaa gaatagtata ccttattttt cattcgttga
     5701 ccagtctttt tttaatttct tttttcgctg gcggagcttt cggaaaaagt cagtcaaaat
     5761 catcccacat tcgtcttcta aaatgccacc ttctacatat gcttggtggt taaaccgctc
     5821 gtcctccaaa agattcatca aggtaccggc tgttccgcct tttggatcat acgcgccgaa
     5881 ataaacttct gctacacgag acaaaatcat cgcgccgctg cacataggac aaggctctaa
     5941 ggtaacaaaa agtgcagcat cttccaagcg ccagcttccc actttttcac aggcttcctt
     6001 gattgcaagc atttctgcat gtgtagtagc atcttgcgtg gtttctctaa ggttatatcc
     6061 tcttccaatc acttttccat ccaatacaac cactgctcca atcggaactt catgaagcat
     6121 ttctgctttc tttgcttctg ccaatgcaag gcgcatccat ttttcttttt ctactgcatc
     6181 aagatttgta tttaccaatt acccttccct gcctttgttt tttcttgttt tactttagca
     6241 tatgataaaa aggctgtaac taactttttt ttctatggta aaataaatac aagaggtgaa
     6301 caagatgaaa atggataaat tacttgctct ttacccacaa gcacagaaaa aaaactctcc
     6361 agcatcagaa gcggatatcc tttcttttgc aattgatgat gcttttatct ggatcaaaca
     6421 agattcatta tctcaacaag aaaccagcct tttgaaagcg ttattccctg taatcaacga
     6481 tcaaaaaaaa cacccatggt atcactatct ttttaaagat gcttcttgtg ttcaagaaaa
     6541 aagctttcgt ttgatccagc ttcacgtcga atcaaaagga gaattcttaa aaaaagaatg
     6601 gcaagatact attttggaat tatttcgcta ttctgctgat ttcttttttt atacagacac
     6661 agatgcgctc ttagtcgaac aaataaaccg tgattatctt gatgctactg aaatcaacgg
     6721 tatttttcta tctttagatg ctgattttga tacgacaacg tctgtattcg ttggttcttt
     6781 ccattcacct ggcaccgacc tcgtcccttt gtttgctgaa gaaagaaaaa tttttttaac
     6841 agagcaaaac aatctttata ctcacagccg tactttttct atgcaagatg tggctttaca
     6901 ttactataca aaagatactg taaaagatag taagttgatc aaaagttaca tagaactgat
     6961 caaacaaaat gaaatggaag tgatcattca agaattatgg aatgaattag gcaatgtcag
     7021 ctctgctgca aaaacactgt ttcttcatcg taatactcta aaatatcgaa tcgaaaaatt
     7081 tcaagaacag tctggtttca atctaaaaaa agccaacgat ttactgtttt gctatctttt
     7141 attgcttcat gaacataatt aaagatagat taaaggggtt gtgacaataa ttttgtcaca
     7201 accccttatt tcgaatgaat agtgttcaaa agctagtttc tcttacatca ttttttcaac
     7261 aaaatgcatt agccggtctt ttacatcttc ggttgaatct ttgattgaat caccataaac
     7321 agagattttc ttttttcctg atttgatttt tgctaacatt cccatcaaag aatccaagtc
     7381 actatctgaa agaccatcta cgatttctag taatttttca tttccatcaa atttgtcata
     7441 gacgaatttt tttactttcg tccgagtagt catatgatgg atcttttcca ttacttttcc
     7501 cgatacaacg actgctgtcg ctacactggc agcggctgct acgcttaatc cgattgttac
     7561 ttttgttgat gttttcataa gtatcagctc ctttttatct atctccatca tagcatagac
     7621 aaaaaaataa acgaactaat ccactcagtg aaatctcaat cctttaggga aaaagttctt
     7681 tactgttcct tttacttgtt tcccaaatcc gacaggtatc ttatctaata ctagcaaaac
     7741 ccatccttga ttcccatcac gttgaaatgt ttctcctgct gtgtaagatt gccattcctt
     7801 ttgagtgatc ggcaagcaag gtatattctc tatctttttt gtagcaagcg ctaatgcata
     7861 gctaggttca aatcgattct ttttgaaatc tcctaaatgc aaacctgtac gtacgacttt
     7921 taaaccatcg agagaagggg ctaactcagg aacttcccaa agatggtcgt tgaacactaa
     7981 aagtcttcca gtagcttcat aatgaaaatc atttgaaaac tccgtccaga gtttttcctg
     8041 ctcttttgtc atttgcactt tacttttttt tcgtgtcttc ttttctttat gcatctgatt
     8101 ttgtccatga aaagtcagct ttgcaacaaa atgtccttca ccctgatctt tatgaggcca
     8161 tatacgtatt gttttttcca aaccagctac gcttccccat tcagaacgtc ctgaactaac
     8221 ggattgagtc aaaggaatct cctcaatcgt tactggataa ttttctacaa gccagctaat
     8281 gatctcttca ttttcttctg gtgcaaacgt acaagtcgaa taaatcagtt gtcctttatt
     8341 ttttagcatt tttattgctg aagacaaaat ctcttgctga cgtttttgac agtatagcgg
     8401 agattcttct gtccactctt ttattgcatt tggatctttt cggaacattc cttctcctga
     8461 acaaggagca tcaaccacga tccgatcaaa aaagcccgaa aaatgaggga caagttctgc
     8521 gggtgcatga tttgtcacta ttgcgttcga aactccccat cgttctatat tttctgataa
     8581 aatcttcgca cgtttcggaa agatctcatt cgtcactaat aaccctttcc ccttcatttg
     8641 agcagctaat tgggttgatt taccaccggg agccgcacac aaatccaaaa ctttttcacc
     8701 gggttttgct gcagcagctg ttccaacgat cattgcactt ggttcttggc tatattcata
     8761 cccagcttga tggaggaaag actttccatt gacagtgcca agaaatccct cattgctgta
     8821 gggagcgggt tgtaattctt cgctatggta agtttggacc atgtccaatc ctgccggttt
     8881 tagtggattc caccgaaatc cttttttcac gcttccttgt tcaagcgcag aaaaaaaatc
     8941 ggatgcttct tcgcctaaaa gaagacgata ttttttgata aattgctgtg gtaacgttgt
     9001 cgcttcctcc ttcattccaa tgtttcgtta gacattttac aatctttttt acgaaaaata
     9061 aaggtggctg atctactttt tcatgttgct gcctaaggtg actgttcctt taagatattt
     9121 tccaagtatt catccgtcac ctcgttttta tcccaaacag cgttcatcat ttcaagaaaa
     9181 tcttgagaag aatcatctga gcgcaaactt cccaatgcat taagccatac caattcaagc
     9241 gacttttctt ctttgatctt cgtgtgacct ttgacatatg agaaaaatgg ccgcttaaat
     9301 agcgaatcca tgtctaaatc agattttgca atgatttcac gaatactttc atggatagaa
     9361 aaaaaatctt tcaataagta gacaatgctt aaaacatcat cggaactgca ttcagctaag
     9421 tagttttcaa aataaacagt gatttcttct aatatcttct cttttaaccc gctgattgat
     9481 ttgaaatgtg tataaatcgg gtatgtagaa caaccgcaga actctgctaa ctctcttgca
     9541 gtaattgact tcattccata ttcttccacg tataccatac ttttgaacag caaatattct
     9601 ttactataat ttgttactct ccccatcatt cttacctccg tctcttttca tctacccata
     9661 aataaataac ataaataatt ctaaaaatat tattgataat tatcaaaaca tatttagtta
     9721 tatccattaa aaatcaattt ttccgcctta aaaacaagaa tatcttgaca aaatacccta
     9781 ggaaataaac aatagaataa acaaggtaac aaaaaaatta aataacgtta tataaaaaag
     9841 aaggcgacac tctgtgagaa taacacagac tgaaatgact ttccactcac agtttttgtc
     9901 taactatata caaaaacaga ataaaaagga ggtatttatg ctaattgaag caagaaaaaa
     9961 agagttactt gttctacaaa tggtcattca aaaaaataat tgttctttac aagaattatc
    10021 caatgactta catattccaa aacggacaat caaagaactg atccgaaaaa taaatgtatc
    10081 actcaagcaa tttttattga ttgatgaatt tatttattct aatcataaag gagagatcca
    10141 aaccaaagaa accgatcaaa ctaaaaagtt agctgttttt tctaagttaa aattatgcta
    10201 cctaaaagaa tccaatcgtt ttaactattt gatgttacta atcaattatc cacaaactgc
    10261 tgtaccaaaa aaatatttac ttgaacaact ttatatatcg ccctcctatc tcgaaaaact
    10321 gacaaaacag ctcaatcatt ccttaaaaaa attccattta cggatcctat ctgtaaaaaa
    10381 ttgctgtact cttgaaggaa atgagttatc tatccgtctc tatctttact tttttctttc
    10441 agatacattt ggaggtaacg attggccatt ttcctcactt gaattaaatg cactaaaaat
    10501 gaacagtaca gatgagcaaa tagaaaaaat ttcaaaacaa gaaaaaaata tctacttgct
    10561 gttaacttta ttcatattac gaaacaaaca acaggcatat tttccaaaaa cttcttctga
    10621 aatcactgaa ttgatggact tattgcagca tacacatgat tattcagaat actttacttc
    10681 tttttcagtg agtcgccctt gtgaagagac agaaacagag agagcctact ttaattattt
    10741 tttctattgt ttttttccaa atcaaatctc ttttcgacaa aaacaggaga ttggtttttt
    10801 attttccaca agcaaaaacc ttatttgtcg acaagtcggt caattgatga cttacttaac
    10861 tcaacagttt cctctcaacc atttagaaaa taaaatacca atttattttt attttcttgt
    10921 gttggcagtt gtttttttcg aactgttggg tgaatccagc agtagttttt ctacactttg
    10981 ctttccagaa gccacgtcca atcattctag ttcttttata caggaaaaga aattaagaga
    11041 aaaaatcgat acaatttttt caaaaaatgg ggaaagaaac caaatcagtc aataccttag
    11101 tcaattgatc caacacttac tacaaacaga aacgaaagag cagttactca tccatttgca
    11161 gataaccaaa cagtttacag gaaattatca tcttcaaagc catttgcagc agttatttcg
    11221 caaagatgct gttaaaatta ccgcatattc agaacatgct gatttgatca ttacagatca
    11281 gcatgagaaa atttcagatg aaacggagac tttctatctg gatacaacgc acaatacagt
    11341 gttatttggc aagttaataa aagcggttca tgaactgtat atgaaaaaag gttatgagaa
    11401 caaaacaaag aggatgtgac aaaattcttg tcacatcctc ttattccaaa taaatggtat
    11461 tcaatcagct aactctcggt attagctcag atcaaagcgc tgatttcaca acttctttat
    11521 tttaatctct tcggttgccg ccgaacaata agatcaagcg caacagctgc aggaatgtcg
    11581 aaagcgctgc tgcaacataa gtcagtgctg ctgcaaataa tacgtgtctt gccatcggta
    11641 cttcttcttc cgtcagtagt ccgccttcac tcaaaatttg gattgctcgc cgagacgcgt
    11701 taaattcgac tggtaatgtc accaattgga aaagtaatgc taaagaaaaa gcgaaaatcc
    11761 cgatattgat taacgtagag ttccagctaa gcaatacacc taccataatc aaggggaacg
    11821 aaatcatcga accaaagtta gctgctggaa caagtgctgc acgaatcttc aatgggacat
    11881 aacccgaagc atcttgtacc gcatgtccgc attcatgagc tgctacacct atcgcagcaa
    11941 ctgaagtaga ctgtgcagtt gcttgagaca aactcaacat cttattacct gaattgtagt
    12001 tatctgtgag atctccggca atttgttgaa caccgacatt atttatctgt tgactttgta
    12061 atatatattg tgctgcttgt gtaccagtca cattgttttt gcttctcact tgatcgtatt
    12121 ttcggaaagt actattgacg tacgctgacg caattccgga aataactaat ccaagaatga
    12181 ccaaaagaaa tgtcggatct aaaaaaccat acattccata accatacatt ttcgtttcac
    12241 tccttttcgt ttactttatt ttatcattag tagtaggaaa agaatgtgaa aagaccttga
    12301 atattcttta attctttttc acaaattccg atttcagttt catcggtcca aatccttcta
    12361 ccttgcaatc gatattatga tcgccttcta ctaaacggat gttcttgact tttgttcctt
    12421 gtttaatggc acctgacgca ccttttactt tcaagtcttt aatcactgtc acgctatcgc
    12481 cctctaacag acggtttcca tttgcatcta ataccactaa tccgtcttct atgacagttt
    12541 cttgttcttc tttgttccat tcgttcccgc attctgggca aatcaacaag cctcgatctt
    12601 catatgtgta ctctgagcca cattctgggc aatttggtaa tgtcatcttc tttctccttt
    12661 aaaatcttta gtgagcacta ttgtaacgga aaaagaagat cttgaaaaga tacatttgtg
    12721 atttttacta caaaaggcac gttttcgaac gaagtatcat tctgtttttc tgctcttata
    12781 cgattggcat atatcttgga tctctttata gatttcctct acttctgcta aatcttttgc
    12841 attcgcacca cttgctaatg gatggcctcc tccatgatgg cgtttagcca attcattgat
    12901 gatcggcccc ttagaacgta aacgtacgcg gtaataccct gaaggctgct gaacaaaaat
    12961 cccccaagcc agcacttcgt caatcactcc aggaagtgaa acgatcgaag ctgtctctga
    13021 atcatcgatt ccatatttat caagaatttc ttgcggaagg attattcttc ctgcaccatt
    13081 ttcatccacc tggatatttt gataaagata accggaaagt ttagcgactt tcatcggcat
    13141 ttgttcaatc tctctgttca aagcacttgc atcaaatgga taatttctca atatcgaagc
    13201 aatctctaat gtacgggacg tcgtggaggg atacaaaaag cgccctgtat ctccgacgat
    13261 tcctgcataa agtaaccgtg cagccttaac gttcatcttt aaagattcag gaaacatcaa
    13321 agcaaattct gcaatcatct cactacagct acttgctttt gtatttaccc acacaagatc
    13381 tccataaggg tcatcattgg gatgatggtc gattttgatc agtttttctg ccaactgata
    13441 tctttgatca ctgattctgg gtgaattagc tgtatcagtc acgatgacta gcgctccttg
    13501 gtagaagaca tcttcaactt cttgcatttc tgctaaaaag cgaagccctt caatcgtttc
    13561 acctacttga cgtatttctt tttctgggaa actttcccgt aatagttcgg ctaatcctac
    13621 ttgtgatcct aatgcatcag gatcagggcg caaatgcctg tggataatga ttttatcgta
    13681 tttttttatt gtatctacta tttcttgctg tactgtcatt tcactcctgc tttctaagaa
    13741 cgttccatta cttgacaaac aacgattgct ttggaaacga tggtgttttc aataaacact
    13801 tcgatatcca gtttagcgga acgtctgccg atttccaata cacgtggacg aatgtctaat
    13861 tcgctttcca attggatcag ccgcaaataa tgtaggttca cttgttcaat caagatattt
    13921 cgtttttggt tcatcaccat tgttttttgt gcgacatcag aaatgatttc gctaagtacg
    13981 ccaaaagaaa tggttccaac gccattgacc atttgtggtg ctactacgaa tttgaactta
    14041 gggttttcca aacgatttcc ttcacggtca gtatcaatcg tatggatatt tccagatatc
    14101 tgatccgaaa tcgtatctgc aatctgcggt tgtcgctgga caagctgcat cgctttcatt
    14161 acatcttgcc gggtaatcaa gccttccaat gtcaagtcat cggaaacgac cggcatgact
    14221 tctagcccat cccagatcat ttgatggcta acagaggcaa tactcattgt tttctttaca
    14281 ctgattggtt ctttcgtcat cacccgatcg atgatctggt ttggcgattt ccctaaaaca
    14341 tcttttgccg taacaatccc catcaaacga tgatggcggt tgacgactgg aaaacgcgaa
    14401 tgctgcgttt cttctgacaa acgctgataa tcagaaatcg tatctgtctg ctgcaaataa
    14461 tgagtctttt cagctggcat atagatatca ctgacaagca tgatatcttt tttgatcaat
    14521 tggtcgctta acgctcggtt gatcatggtt gcgactgtaa atgtatcata agaggtgcgt
    14581 aagatcggca tttcaagatc atcagctagc tttgcaatct cagcagtcgt attgaatcct
    14641 cctgtgatca atactgcggc gccatcttcc aatgctaatt tttggacttc cgcccggttg
    14701 ccgacgatca ttagtgatcc tggcgtaata tagcgttcca tggcatgttt agtcatcgcg
    14761 ccgatgacga atttattcaa gaccttgtct aatcctgccg ccccgcctaa aacgtcccct
    14821 tcaatgatcc tgacgacctc gccaaatgtc aaacgttcaa tatgtttttt taatttgcgt
    14881 tcgatacgga tggtccctac tcgttgaatt gttgaaacta gtccgacatt ttctgcatct
    14941 ttgattgcac ggtacgctgt tccttcactg acattcaatt cttttgcgat gcttcttaca
    15001 gaaattcgat tgccaacagg taaactttca atatattcta aaatcaaatc atgttttgtc
    15061 gccattttct gcctacactt ccagcgtttc cgagacgctc attatttttc cttcactatc
    15121 ttccagtaac tctacaaaag attcgggatc ttgttcaatg acagggaaag tattgtaatg
    15181 gattggaact actttcttgg cacgaattgt ttgcgcagcc tttgctgcat cttctggccc
    15241 catcgtatag ttatcgccaa tcggcaagaa agcgacatca atatcgaatt cttctgcaag
    15301 caatcctaga tcactgaaat aagcagtatc ccctgcatga taaatcgttt ttccttctgc
    15361 ttgaataata attccgctag gctcgcccat atactgaacg ataccgtcta cttcatagct
    15421 tgaactatgc tgtgcatgta cgaattttac cacgccgaat ggaaacgcat gttttccacc
    15481 gatattcata ccgaatgaat ctactcctct gctgttcgca taatcagcaa tctcaacaat
    15541 actgataatt gtggcttgat tttcttttgc aataggaatc atatctccta tgtggtcact
    15601 atgaccatga gtaatcagca accaatctgt ctttacttct tctgcagtta agtctgtcaa
    15661 tggatttcct gtaataaacg ggtcaatcat cacgcgttgg ccattttcca tttcaattgt
    15721 taaacaggaa tgtccatgat acgtaatttt catattttac acctcgcgtt ttctctgtat
    15781 cttttttatt aaaaacgatt tcatcacttg cacatcaatg aaaaaatata gctgctaaat
    15841 atattttcat tggattgata gtacagtatg tacaaagcaa ttgtaacaga taatacagga
    15901 tgcaccaagt accaagcaga tataatctca agtttgaggt ctctgctctg cttagcttct
    15961 cttctcgtcc cttaactaat taaatcagcg taaataggat ggacgatctt ttctaaatcg
    16021 gctactttta tccgaaggct tctcccgatt tcaccgcttg acacaattac ttcttctttt
    16081 tcttttaaag aactgtctgc taaaaaacaa taatcaggat gtgcgagttt tattccaata
    16141 ggggtgtttg ctccgtgggg atatcctgta tgcattaata caaaatccat tccaggaaaa
    16201 ccaactttac gatctttcgt cacttgtctc gtttttttgt aatctaagtg atcgttcaaa
    16261 ggaatcaatg cgatgatcac cccagttttg tttcctttca ctacgagagt tttacatatc
    16321 aaagctggat caatccctct tttttgtagt tcttctgtga aagattcttc taccacatga
    16381 ctaaaatcaa gtggttgata gctgatcttt tgttcttcta aataacgttc gacttttgtt
    16441 tgactcatca ttgattcact ccctttattc tatcgtttat tataaagcga gggatgctgt
    16501 attcaaaaat tatttgtttt tcgcaaaaaa agagcaagac gagcactcta tagagaggtt
    16561 catcttactc tttttgttta ttttttattt cgacgttgag tagcttccat aatgactggc
    16621 aagatcactg ggcggcgttt tgtttgttca aataagtaac ggcctaattg atctcggatg
    16681 tcttgcttta atttgctcca ctcaaaatca ttgctttcta aatgtttctc aacgattgtt
    16741 tcaatcatat tgctgctttc tttcatcaga tcacggctag cttttacgta aacgaatccc
    16801 cgtgaagtaa tttgaggttt tgaaatgatt ttcttttctc gccgactgat agtgacaacc
    16861 gctacgaaaa tcccgtcttc tgacaagatt tttcgatcac gtaaaacaat gtttccgata
    16921 tcacctatgc ctaatccatc aatcattaca ttttctgcac ttgtagttcc tgcaacactc
    16981 atacgcttgt tcttatattc cagcacgtct ccgcgtccag taatatagat atttttgtat
    17041 ggcatcccta ctgcatgagc caaatctgca tgagcagcta attcacgata ctctccttga
    17101 actggcacaa aatatgttgg tttcatcaaa ttgatcatta attgcaagtc attaggattg
    17161 gcatggccag aaacgcgcat attctcagag atcaacttca ctgttccacc agctcgataa
    17221 atgatatctt ccgttttcgc cacgatggtt tccatcgcga tgcttggcgt agtagtgata
    17281 taaaccaaat ctccttcttc aatcttgaca ttacggtgtg taccgtttgc cattttttgc
    17341 agagacttga tgggttcacc cattcggcca gtttctaaaa tgatcagttc ttctggatca
    17401 tagtttttca tgtctttcaa cgtaacaagc agatcttcac ttggtaattg aagtttttct
    17461 aaacgcatcg ctgtgcgaat aattcgttcg aaatcttgac cagtcaagac aacttttcgt
    17521 tgtgcttttt ctgctgcatc caatacttgt tgcactcgtt gcaaattact tgctacacaa
    17581 gcgacgatga tacgcccttc ccaatatttg atcgtatcaa atacttcatc tgctatttgg
    17641 gcttcagaag ctacaggctg aggattttct gcatttgccg attcacttag taaggctaag
    17701 actccttctt tgccgatttc cgccaatcgt gcataatctg tttgatacat tgggatagcc
    17761 gtttggtcaa atttaaaatc tcccgtataa acgatactac cttcttttgt tttcagattg
    17821 atccccactg aatctggtat cgtatgagtg gtacggaaaa agctcactac tgtttcacca
    17881 aagtctattt ctgtatgctc atctaccaca tggaaatcct taaatccttt ggctgcttca
    17941 ttacgactga cattcaattt tgctaactcg atcgtcaact ctgtcccgaa tactggtaca
    18001 gaaatttttg acaacaagta aggaagtgcc ccgatcgcat ctgcatgtcc atgtgttaaa
    18061 aagacaccag ctacacgatc aatgttttct tctaaatacg taaaatcagg gattacgacg
    18121 tcgatcccca acaactcatt ttcaggatat tttagcccac aatctaaaat aaaaatatcc
    18181 tcgcccactt ctgcgacata catgtttttt ccattttcac gaacgccgcc taatgggata
    18241 attttaatgg tactcacaaa cttcacctct tcttatgaca tccaagttta aagatgtcga
    18301 ttttcttctt tatctaaata tatgagccat tccaatgaag catatgcaaa atcactattt
    18361 ctcaacttat ggagaatcag caggaaaatt accagcacat ccgcgttctg acagttggat
    18421 gggcatttta ttttggatat acttcattaa caaaatggat cttttgcgaa acgctatagc
    18481 cagaatactt atataagtat tcagctgttc cccattatta tacaacaaat aaactaaatc
    18541 gctagtatca gcaattgtta gaacaactat gcacgtaaaa atccctctgt agcatctagg
    18601 atttcttttg ctattcctct ttcatttctt cttcgtcggt ttgaaacata cttttttcat
    18661 tttaccacat tttttgcaat aactatagtg actttttata tatacagaac ctcatgttga
    18721 tggtgtgcaa acagcataag atttaagcta gctttaagat aggttgtcta ttatcaaatg
    18781 catctactag gagggatgca aaatatgaat tttatgaaac gtgcatggaa aagtacaaaa
    18841 gtaaaatggg gacgttcatt gttattgttt gccgtgttca cagccattct tatttttgtg
    18901 ctagctggcc tcacgattcg aagcgctgca gaagaagcag cgaatcaagc acaaaaagaa
    18961 gttggagcaa cagtgacttt aagtgccaat cgagaagctt catttaaaaa acaggaacaa
    19021 acttcttcaa gcggttctac cactgaagaa cgtccagatc caggcagttt ttctcttaca
    19081 ccagtttcct taacggacgc ggaaaaaata gctgaattag ataatgtaaa gagttattcc
    19141 tttgaaagtt ccgcctcagc tatggcaaaa gatggaataa ctgccatcac tagttctgat
    19201 tcaagtgaag acagttcaga aactactgat gcaggcggtg aacctgctgg aggaatgggc
    19261 gggaatccgc aaatgactca agcagacttt caaatcagtg gtgtgtcagc aactgcacaa
    19321 aatagtaatt tttctgatgg aacagcaaaa atcacggatg gtgaaggaat agatgacagc
    19381 gacaaaggca caaacaatgt agtcattgat tctactctag cagaaacaaa tgacctggca
    19441 gtcggagata ctttcacaat cacgagtact gaagatgaag ataccactta tgaaatgacg
    19501 atcaaaggaa tttatgaatc cagcgaaaca agcggcagta tgggtatgaa attcaacttc
    19561 atgaatccgt cgaatacact ttacacttct tacacttttg caaatgaact aaatgggaca
    19621 tctgacgata acacgataga ttctgctatt tacactctat ctgatccaga taaaatggat
    19681 gagtttctca aagaagctga gaagctgatc gacacagata catttagctt acaatcaaat
    19741 gattccatgt atcagtcaat gttggaacct ttaaacaacg tggcaagttt ttctaaaaat
    19801 gttgttttac tagtggctgt agccggtatt atcatactta ctctgatcat tatgattacc
    19861 attcgggagc gtcggcatga gttaggcgtc ttgctatctt taggagaatc cagaagtaaa
    19921 atcattctcc aattgtttac cgaagtggct atttgtatga ttcttgcatt aggagttgct
    19981 tcgcttagcg gaaacgtcgt cgcgaatgcc gtgggacagc agctacttga ccaacagaca
    20041 gaaaccacga cacaaaacca gcaagctcct ggcggtggac aaatgccagg taacagacaa
    20101 gaacaaggcg gtcaacgcga tggtcaacaa ggaaccacga ataatccatt tgctgtttct
    20161 gatcaagtca gcgaattgga aatcaatgtc aaacctgcac aattgggact attagccgga
    20221 gtagcatttg gaatcagtct gttttctgtc tttttagctt ctatagggat attaagatta
    20281 aacccaagaa aaatcctatt aaactaaagg aggaatttga tgttacggac agaacaattg
    20341 ggattttggt atcaagatcc gcaagatgcg ctttataaag atgtagaact gaatttcgaa
    20401 gctggaaaaa tgtacgctat tttaggagca agtggttctg gaaaaacgac ttttctttcg
    20461 cttatttctg gactagatgc accaaaagaa ggaaaggtat actatcaaga tcgttcactg
    20521 aacaaaatcg ggttaagaag ttatcgtaaa aatgatgtct cgattatttt ccaagcttac
    20581 aacttgcttc cttatttatc ggctctagac aacgtcatag cagcaatgga aatcactaag
    20641 accaagcaag agaattatcg acaagttgct ttagatcgac tggctcgtgt aggaattgat
    20701 gaaatattag caaaaaaaca ggtgaccaaa ctttcgggag gtcagcagca gcgagtcgct
    20761 atcgttcgtg ctatctgctg tgaacatcaa ctaatcgtag cggatgagcc tactggaaat
    20821 ctagatgaaa caacttcaca agatatcgtc aaacttttcc aagaaatcgc ccatgaacaa
    20881 aatcgctgta ttatcatcgt gactcatgag attgaagtag caaaaagctg tgatgaagtc
    20941 tttgaactaa aaaataaaaa atttcaaaaa atcgaagttt aaaaaacagg ataatgatca
    21001 aataaaaaat ccgaaccata tctgtctcgc agatatggtt cggatttttt atttgcttga
    21061 ttcaattagt aataagtggt ttttattttt tttcgtcttt tcgagaaaac ttgtctttga
    21121 cttcgtcgcc taaatttcga gctttttctt tgatgtcagc acctagtgat tgtgctttcc
    21181 cttctgtttc tttgctcttg tcgtctgttg ctttgccgta tgcttctttt ccttcaccga
    21241 ctactttatc tttcatatct ttagaacgtc cttttaaatc tgccattgtg cttcctcctc
    21301 ttagtttgtt tattgatcta ccttcagggt aacatcaaca acagatacag acaaacagaa
    21361 cgctcgtttt ctaaaaaaga tagttagagc tgttgattaa aaactttttt cgaaagtccc
    21421 ccatactttg acttcttttt cttggaccat tatttctcct ttagcgataa ctgtatcaat
    21481 atcaagcgtt tctttatcca agatacacag atctgcatca gcaccaattt cgatttttcc
    21541 ttttttatcc aatttcaata tacgtgctgg attactggtt atagctcgta aggcgatttc
    21601 caaagggata ctttcttttt gcacagcttc tttgatccct actagcaatg ccttggcact
    21661 tcctactcct aaccctagga aatgattgtt ttcatcaaaa taaggcaagc ttccttgtcc
    21721 atctgaggtc atcgtgaaat tatctaaaga aacatcttcc tcgatcaatc gtttcagtgc
    21781 tttgctgaag cgaacttcac catctgtctt ctcccaaaaa tcaggatctt cgctagcagt
    21841 gaagtcaatc gtgccaccac gtttggcaaa tgccacgcaa gcttcaaata attctggtgt
    21901 gcgatttgca tgagtaggca aaaattgtgt gatcggaatt tctgtttctt ctacgattcg
    21961 tgtcaatagc tctagctttc tttttcctcc gcctaagtgg acattgatga tcccagcttt
    22021 tccggataac atgcctccta cacgagcatc tgctactgca cgagcgaact cttcaaaact
    22081 tggctgagaa gaacggtgat cggatactgc gatttctccg attccgataa ttttatcaat
    22141 tgtcaaaaag tctttgatga tagaatctgt tactgttttt accggcaatc ggtacgaacc
    22201 ttcgtataca taagtggaga ttccttctgc ttccagacct ttcgctttgc tgatcaacgc
    22261 agtcatatct ctaccttctc cgtctgttcc caaacaaccg acaactgtcg ttacaccagc
    22321 tgtagtcaat tggctcaatg tgacttctgg cgttcgattt tgataaccgc cttctcctcc
    22381 tccacctaaa atatggaaat gacagtcaat gaaacccggg gttagtactt ttccctcacc
    22441 tgaaagttct tctacttcca ctccttcgta gccgccttct agctgttctt ctacagccaa
    22501 aatcttccca ccggcaatca gtacatccat ttttcctaag taatctggtg caaacacttc
    22561 aatttgtcga atgattttca tacatttttc ctctttcttt aagtataact gatgatagga
    22621 tcttaaaaaa taatccaaac gataggatct ttactccttt gattttaccg taaaatgacg
    22681 gttcttggag tccttatcta ctgtttggat tactttttta tttacaggtc tccagtacta
    22741 ctgcagacct attgcaatgg caatcatgat gaaaatagtt cctaaaacaa acaggaatcc
    22801 ttgcatcttg atttggaatc ttgcccattt tgcccattcg atccgtgcaa cacctagcac
    22861 accaatcaag ctggctgata cgggtgtaaa agcgtccata aaacctgaac caagctgata
    22921 agcaagaact gctacttgtc tggatacacc tactaaatct gccagtggag ccatgattgg
    22981 catagtcaaa gctgcttgtc ctgaatttga tgtaacaacc aagttgaaca aactttggaa
    23041 gatgtacatc gcccaagcac caatgacagc tggaacaccg gtcaacgccg tcccgatccc
    23101 atgcaaaatc gtattcaaag ctgaaggaac agatgcatca gatcctccca agacaagaag
    23161 aatccctttg gccataccta ctacgattgc tgtaccagct aaatcagctg caccagattg
    23221 gaaagaagaa gcgatgtcat tgactttcat tccatctaat ttgaaaagaa cagcaatgat
    23281 tccagcaact aatcccatca caaagaattg agaagcgatt tctggaatgt aatagccttt
    23341 ttgagtcacg ccccaaacga tccagacaag gacaactaac atctctaata agatcaattt
    23401 atgcccaagc atgaattttt tattttcatc agatgtcttt ttgatatgag aacggaaata
    23461 atcatctgat ttgtaagtca acgaactttc tggtttttta cggatttttt ctgcatatat
    23521 catcatataa ccagcggcta atgcagtaac aactacccac ataatcaatc ggaatgtcgc
    23581 accagacaac acggggattc cagcaatccc ttgagccacc gctacgctaa acgggctcat
    23641 ccaagaggtc gcatttccga cttgagatgc gacataagtc acggttactg ctacgatcga
    23701 gtcatatcct aacgcaatga caaatggaac catcaccatt gagaatggaa ttacctcttc
    23761 tgccatcccg aatgtagcgc caccgaatga aaaagcaaag aataatagcg gtaaagctaa
    23821 acgctccagt cccttagttt tactgataaa cgcatagata cctgcgtcga tcgctccggt
    23881 acgcataata ataccaaaag cacctccaac aacaaggatc aatgcagcga tccctacagc
    23941 agatccatac ttatctccag atactagtcc ttcaaaaaca aaatttaaga aaccaaagcc
    24001 gccaaaatca tctgttcccc atattttggc tgttttatgc aattttttag aagtatcata
    24061 gatattttcg ccgtactgat cgtaaagcac atcatctgtc aaggagattt catctagttt
    24121 ttcctgcgta agattttttt ctccgtcagc aatgactttt tccaatcctt tttccggaac
    24181 atccagtttt tcacgttctg ctggatgatc ttgcagttct tctaattgat caaacacata
    24241 cgacttatcc agctcgtaag cataacggaa ggaatcttga cgtaaaacag tacgagtact
    24301 tgtttcgcca tttgcatctt tgtattcaat atcttgcgtg ctgaactttc ctgctggaac
    24361 gacaaaagtc agtatccatg caaagatgac tacaccaaaa ataatgacat acgtatgggg
    24421 tgtcgataat ttagtgaagt cgcgtttcgg ttttcctgaa gaatttgttt tcttcaaatt
    24481 tatttcttcc tttctttttt cagtaatttt gatgaataaa aaatggataa tcaaatgaat
    24541 tatacagtaa aaatgacatt tccacatgaa taatttatta gaaaatcact tttttctatt
    24601 ttgttttttt tctcctatgt atgattattt ttttctcttt ccatttatat taagtatttt
    24661 atttctctgt ttttccttaa aattcttttt ttatttttag attagagaaa atctcgtcct
    24721 gtttttttca ttttacaatc attgaaaaat tgaatttcat tgcaaaaaaa ataataaaca
    24781 cttataaata tccattatct atccttcaat ttttgtgtat tttatttcta ttagaaaaag
    24841 gtatcctgtt ggacaatttt gttatatcag gtaaacttca ttgcaataat gataacaaat
    24901 gtactataat tactttgtaa agagttttgg ggaagactct ttcatcaacg tgtattaaga
    24961 gacaagaaag aatccatatg gattctttct tgtctctttt tccactactt tttatttttc
    25021 tgacactaca tattcttata actcatttct cataactgtg aaacaactta taaaaataac
    25081 aaactttaaa caaaacaagc ttaaaatcaa agatgatcca tcttaaaata actaaaacaa
    25141 aaaaagtagt cgttgttaat cctcattaat aatcgttttc tttttttcaa acgctccatt
    25201 tttatgtgga acattatttt tttaaggaac tttgtcaaca tgtggataac tattttccac
    25261 ttgtgtcctg gactagctgt tttgctgtaa aatacaaaac ttgctgcagc aaaaagatcg
    25321 ttgcaagaga ggctgttccg cagatcgctg gatctagatt tggcaaagtc aagactgcat
    25381 catgtaaatt ggcgtggttg tccaaaacca aatcagcaaa ttcaaataat cgcaaaccac
    25441 tgctatgttg cgatttgata cttcgtgaca aatcaaatcc agtaacaatg attaatggat
    25501 gaccattttc tttgatccac tgagctagtt cgatgattgc cgggtttctt ccttcattcg
    25561 aaagaagaag aaaaatgtct tctgatttga cagaaagctg atcaataatt gcctgtcctg
    25621 caccttctag cgtttcatag acacctccgg ctggattttc aatcaatata cttggtacaa
    25681 gatccggggt ttgatcccaa aattcaaatg ctacaccact tagtgtgcgg ctagcatata
    25741 tctgcaatct accaccttga ttaatttgtt tcgcgatcca agtgccagct tgaagcatca
    25801 gcggctcttc tatccttaat ttctcttcca attggtgata atagtcaaaa taacataaac
    25861 tcatttatct ctcccgccta gctatacttg acatgaatag aaacagctgc ctaatctaag
    25921 gaagtacata aaaaaacagt agttagacag taacacatgt ggtctttgct gtttcaaaca
    25981 caaaaaaggc attgaacgaa tacgcccaat accttgacat agcaaataaa acaacgtgca
    26041 gaccatggaa aatatctaca taggggtaga attttcaccc tagattaggt acaataaatt
    26101 aggtcgatgc actgcattga ctatggcaaa atgatcggtc agggtgtatg tgtgtgactg
    26161 gtcattccct gattcttagc gccaactaag ggtcagggag ccttttttta ttcagctgtt
    26221 tctatctgaa tttattgtaa gtaatctctt atccaagtgc aagcaagaaa atacaaaaaa
    26281 acattggtat gatttatata tatataaata acataaaaaa aggaatggct tatcccgata
    26341 caacaagcat tcctttaaaa aagattcttt tatataagtg aaaaaagctt ttttccacca
    26401 attaaataaa tctctcatct caatagttta tccattattt tatctttttt tgcgtatacc
    26461 tactaaatat taccgtcttc ttctcgttct tctactttgt tcgagagaat ctgtactaga
    26521 aaaagtagtt gtatgtctac cttttctgcc tatccgagac tttcttttca tatatgggat
    26581 ataaatgatt agatacagta cagcaaaaaa taaagcaaat acgcaagctt cccaactacc
    26641 taacgccaat tcaaccatca aggtagcaac cccaacggat gctgcatacc agataaaaat
    26701 cagaaacgtt tctttttttc tgaccatgcg aaacatgata aatagactaa taagcaatag
    26761 tggcaacaca aatatccaat tgcttccttc catcagccac ttgagtatat caagcagcga
    26821 ctgtgcaaca gcgactaatt ttcccatagt gaacacacac ctttttttat aattaaaaaa
    26881 ttcgcctttt tattctacta tgaatcttct ggcttggctt tcatttctct tatgtaatca
    26941 ttttctttta tacaacttaa aaaaaaatta aaccattagc ataatatttt ctgaatctat
    27001 tcacgaaagt ctttttctat ctttcgtttt ccacgactca actgatctag agtcaaaaaa
    27061 ctaaaacgac agttgcgcaa atgacgcaca agctgccgct ttaataacaa atagcctttc
    27121 attctcagca ggccacttat ttccagttaa ctttctgttc ttagcttttt actcaactgg
    27181 ataatatatg cacttaatga agtcccaatt tccgaatgtt gaagtccata ttcaatattt
    27241 gtcttcatat atcctaactt atcgcctacg tcgtatcttt ttcctttaaa ctctctcgca
    27301 tagaccgcct ctgtctggtt aagagtctga agtgcatccg ttagctgtat ctcgtttcct
    27361 gctcctggtt cttgagtttc taatatctca aatattttag gagtcagtag ataacgtccg
    27421 ataatggcta aattacttgg tgcttttccc atttcaggtt tttctacaaa cccttttact
    27481 ctgcaacgac ccttttcgct atctgtttta ggatcaataa ttccgtattt agatgtttca
    27541 ttttctggta cacgcatgac ggcaacagcg gaagcttgtg tttcttcata atccatcatc
    27601 aattgttgag tcaatgggat atcatctttc atcaaatcat cccccagcat gacgacaaac
    27661 ggttcatttc ctataaatgc ttttgcttga agcacggcat cccccagtcc tcttggatga
    27721 gattgacgga tgaagtgaag attgacttga gtcgtttctt caactaaagc gagtaattct
    27781 gttttttcct tttcccgcaa attgttttcc aattcgatat ttgcatcaaa gtgatcttca
    27841 atgggtcttt tttcttttcc cgttacgatc aagatgtctt cgattcccga atccaatgct
    27901 tcttccacaa taaactggat cgttggttta tccacgattg gaagcatttc ttttgccatg
    27961 gcttttgttg ccggcaaaaa acgtgttcct agcccagcgg caggaatgac tgcttttttg
    28021 accttcactt gct
//
LOCUS       DAXQKX010000033        26873 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.033, whole genome shotgun sequence.
ACCESSION   DAXQKX010000033 DAXQKX010000000
VERSION     DAXQKX010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26873
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.033"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            40..1044
                     /locus_tag="ACF3MF_001604"
     CDS             40..1044
                     /locus_tag="ACF3MF_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3927597.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            1045..1989
                     /locus_tag="ACF3MF_001605"
     CDS             1045..1989
                     /locus_tag="ACF3MF_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3927598.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            1989..2951
                     /gene="opp4B"
                     /locus_tag="ACF3MF_001606"
     CDS             1989..2951
                     /gene="opp4B"
                     /locus_tag="ACF3MF_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HFE3927599.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            2978..3892
                     /locus_tag="ACF3MF_001607"
     CDS             2978..3892
                     /locus_tag="ACF3MF_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFE3927600.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            3918..5699
                     /locus_tag="ACF3MF_001608"
     CDS             3918..5699
                     /locus_tag="ACF3MF_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFE3927601.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            6047..6733
                     /gene="rnc"
                     /locus_tag="ACF3MF_001609"
     CDS             6047..6733
                     /gene="rnc"
                     /locus_tag="ACF3MF_001609"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HFE3927602.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            6753..10334
                     /gene="smc"
                     /locus_tag="ACF3MF_001610"
     CDS             6753..10334
                     /gene="smc"
                     /locus_tag="ACF3MF_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HFE3927603.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIETALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            10343..11152
                     /locus_tag="ACF3MF_001611"
     CDS             10343..11152
                     /locus_tag="ACF3MF_001611"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFE3927604.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            11163..12161
                     /gene="ftsY"
                     /locus_tag="ACF3MF_001612"
     CDS             11163..12161
                     /gene="ftsY"
                     /locus_tag="ACF3MF_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HFE3927605.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            12348..14615
                     /gene="gshAB"
                     /locus_tag="ACF3MF_001613"
     CDS             12348..14615
                     /gene="gshAB"
                     /locus_tag="ACF3MF_001613"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HFE3927606.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(14704..15156)
                     /locus_tag="ACF3MF_001614"
     CDS             complement(14704..15156)
                     /locus_tag="ACF3MF_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HFE3927607.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            15306..16256
                     /locus_tag="ACF3MF_001615"
     CDS             15306..16256
                     /locus_tag="ACF3MF_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFE3927608.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            16249..17208
                     /locus_tag="ACF3MF_001616"
     CDS             16249..17208
                     /locus_tag="ACF3MF_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFE3927609.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            17205..17960
                     /locus_tag="ACF3MF_001617"
     CDS             17205..17960
                     /locus_tag="ACF3MF_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3927610.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            17983..18936
                     /locus_tag="ACF3MF_001618"
     CDS             17983..18936
                     /locus_tag="ACF3MF_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HFE3927611.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(19580..19876)
                     /locus_tag="ACF3MF_001619"
     CDS             complement(19580..19876)
                     /locus_tag="ACF3MF_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HFE3927612.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            20231..20587
                     /locus_tag="ACF3MF_001620"
     CDS             20231..20587
                     /locus_tag="ACF3MF_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFE3927613.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            20597..21496
                     /locus_tag="ACF3MF_001621"
     CDS             20597..21496
                     /locus_tag="ACF3MF_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFE3927614.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            22016..22744
                     /locus_tag="ACF3MF_001622"
     CDS             22016..22744
                     /locus_tag="ACF3MF_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFE3927615.1"
                     /translation="MKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEAG
                     DEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYAA
                     ADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAVS
                     LVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSVP
                     GKSVKLAQQYSTKLVWTLEDTPNN"
     gene            22889..24916
                     /locus_tag="ACF3MF_001623"
     CDS             22889..24916
                     /locus_tag="ACF3MF_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HFE3927616.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGHSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRIDIPVENQRIGTFEGKLSWILADVPGN"
     gene            25024..26121
                     /locus_tag="ACF3MF_001624"
     CDS             25024..26121
                     /locus_tag="ACF3MF_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HFE3927617.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            26428..>26873
                     /locus_tag="ACF3MF_001625"
     CDS             26428..>26873
                     /locus_tag="ACF3MF_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3927618.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRK"
BASE COUNT         9012 a         4655 c         5679 g         7527 t
ORIGIN      
        1 agaaaaactt ccatttagga agcagagagg ggtattcgat tgtccgataa ccaattatta
       61 gaagttcaga acctacatac aggattccga ctcaaagatg actattacga tgcagtagat
      121 gacgtttcat ttactttaga caaaaacgag attttagcaa tcgttgggga atctgggtgc
      181 gggaaaagta ccttggctac tacgattatg ggattacttg atcctaataa cacaaaaatt
      241 acaggtgaga ttttatataa cgatctgaat ttaatcgacc tgaacgaaac gctctataat
      301 aaaatccgcg gaaatgatat cggaatgatt ttccaagatc cgttgtctgc attaaatcct
      361 ctcatgagaa tcgaagacca gatcaaagaa ggactttcct atcacacaaa gatgaatgca
      421 gaacagcgtc aagctcgtgc actagaattg ctagaacaag tagggattcc taatcctgcg
      481 agagttggac gccaatatcc ccatgaacta tcaggcggta tgagacaacg tgtcatcatc
      541 gcaatcgcaa tcgcctgcaa acctccaatc gtcattgcag atgaaccgac gacagcccta
      601 gatgtaacca tccaagcaca gattcttgat ttactgaaag accttcagga agaaacaaaa
      661 acagggatca tcttgatcac tcatgactta ggagtcgtag cagaaatggc tgatcgagtg
      721 gcagtgatgt atggcggaca gttcgttgaa gtagcaggtg taaaagaact gtttgatcat
      781 cctaagcatc cttatacacg ctctttactg aactctatac cacaagaagg aaatcatgat
      841 gcagaactcc atgtgatcga aggtgtcgtt ccttctctga aaaacatgcc tcgtaaaggt
      901 tgtcggtttg caccacgtat tccatggata ccagcaagcg atcatgaaga agagcctatc
      961 cttcatgaag tcgcaccgaa ccacttggta cgttgctcct gctataagca tttccacttt
     1021 agagacgaaa aaggagaggt gtagatgaca gaattaatca caatcaaaga cctgaaagtt
     1081 cattacccta ttcgcagtgg attcttcaat cgagtaacgg atcatgtata tgctgtagat
     1141 ggtgtggatt ttattatcga aaaaggaaag acatatggtt tagtgggaga gtctggctct
     1201 ggaaaatcta ctacgggaaa agccgttgtg ggattagaaa aggtaacagc cggacaaatc
     1261 atgtatgaag gaaaagatgt aacgaagcga agcaaccgca aaaaaatggg ttataacaag
     1321 gatgtgcaga tgatcttcca agattcaatg tccagtttga atcctaaaaa gcgagtgttg
     1381 gatatcattg ctgaacccat ccgaaatttt gaacggttaa gcgatcaaga agaaaagaaa
     1441 aaggtaaaag gactgctaga tatcgttggg atgccggaag atgcgctata taaatatcct
     1501 catgaatttt caggcggaca acgtcaacgt ctaggagtag cccgtgctgt tgctaccaat
     1561 ccaaaactga tcgtagccga tgaacctgta tctgctctgg atctatctgt tcaagcgcaa
     1621 gtattgaatt tcatgaaacg aatccagcaa gaatacggcc tcagctattt attcatttca
     1681 catgatttag gtgtagtaaa acacatgtgc gacaatatcg caattatgta caaaggtcga
     1741 tttgtagaaa tcggtacaag agaagacatt tataatgacc cgcgacatat ctatacgaaa
     1801 cgtctgcttt cagctattcc gcaaatcgat gtagaaaata gggaaagcca caaagaaaat
     1861 cgacgaagag tagaacaaga gtatatccaa aaccaaaaag aatactatga tgcgactggt
     1921 cgagtctacg atttgcgtac gatcacaact acacacaaag tggcgttgaa agatggaggt
     1981 gcaagctaat gtggaaaacg attctgcgac gtgttttatt gatgatcccg caagttatta
     2041 ttttaagtgt tctgatcttc ttattagccc aagcgatgcc gggggatcca tttaccggtt
     2101 tgatcaatcc aaatcaggat ccggcagtga tcgaacagat gcgacaagca gctggcttga
     2161 atgacccatg gtatgtccag tacttccgtt ggatcggaaa tgctttgcaa ggcgattttg
     2221 gtcaaagttt cttatacaaa cgctctgttg ctgacttgat cggcgaacgg atcatcaaca
     2281 ctttatatct atcgatcttg acagttgtcc ttacttattt gattgctgtg cctctgggga
     2341 tgcttgctgg ccggtatcaa aattcaatct tggataagat tgtcgtaatc tacaacttct
     2401 ttagttttgc tgttccttta tttatcttcg gcttgatcat gctatttgtt tttggttatc
     2461 gtttaggctg gttcccaaca agtggatcac aaacactagg tttgcaaggt ggatttatca
     2521 ctcaatggat agaccgtttg aaatatattc tgttaccatc aattacccaa gcatttttgg
     2581 cgactgccgt cacaatccaa tatctgcgaa gtgaagtaat cgattcgaaa tcgctcgatt
     2641 ttgtcagaac agcccgttcc aaaggggtac cgacgaataa agtattcagt cgacatattt
     2701 tccgaaatgc agcgttgccg atggcttctc aaatggggta tgaaatcact tcgttgattg
     2761 ctggttctgt agttatcgaa aagatttttg gttatccggg agtcggaaaa ctatttattg
     2821 attccatcgg ccaacgggac tataccgtga tcacatcctt agtattgatt ttaggaatcg
     2881 cgacgctagt ggggacatta ctttcagata tcatcatgag tatcgttgac ccgcgtattc
     2941 ggattcaata aaaccaatca gaaaggagaa tggatcgatg agtgaaaaaa acaatacagc
     3001 agttcaagaa agtattcctc ctatggggat acgaatgatt gctcgagaat ttaaaaaaga
     3061 taaaattgct attttttcat taggtttgct agtggtttta ttattagtga tctttatcgg
     3121 tgcgatgctg accgatcaag acaaagtgat gtatgttagt atcttcgaca aatacgctgc
     3181 accaggaaca gtttcgacac aaggacaaaa gttcattctg ggagcagatg aaggcggacg
     3241 tgatgtatta ggacaattga tcataggtgc tagaaactct gttacgatcg gatttgcgat
     3301 cacgatcctt acttcgatca tcggggttgg attagggatc atctctggct actacggagg
     3361 gatcattgac aacatcttga tgcggatcgt tgattttatc atgattctac cgatcatgct
     3421 gatcattatc gtcttcgtat cgattatttc cagatacaat gtctggtcct ttatattcat
     3481 catgagtgca ttttattggg tagctaaagc ccgattattc cgaagcaaga cattatctga
     3541 agcaagaaga gattatgtca gtgcctcaaa aacaatggga accaatgatt ttaaaatcat
     3601 gttccgcgaa atcatgccga atctaagttc attaatcatt actaatttga cgatgaactt
     3661 tgcggcaaac atcggtatcg agacaacttt gactttctta ggtttcggct tgccggcaaa
     3721 tgtacctagt ttaggtacat tgatcggtta tgcaagtaac ggagaagtct tagtgaatcg
     3781 gcaatggatc tggttacccg catcaatcct tattttagtt ttgatgttga gtatcaatta
     3841 tgttggacaa gcattcaagc gttctgcaga tgcgcgccaa cggttaggct agtatagaag
     3901 cgaaggggga aataggaatg aagaaaacga tttttggatt tgcagcgctg atgtctgctg
     3961 tcgttcttgc agcatgcggg ggcggaggta cagatacctc tggaaacaac tctggaggca
     4021 acggcaataa caaagaggaa ttaacttttc caattgcaac aaaaaataat gatgatgcaa
     4081 tcgaagacgg cgaattagaa gctgcggtcg caacggacag tcagtttaaa ggattgttcc
     4141 agtgggagtt ttaccaagat tcatatgatg cagcttttat ggctccttct catgaaccgc
     4201 tatttgcaaa cgatgacgat ttcagaatca cagacgacgg agctgcaacg cttgatctag
     4261 atgaagatac gaaaaaagcg acaatcaaag taaaagacaa cgtcaaatgg tcagatggtg
     4321 aagatgtaac ggcggacgat gtgattttcc cttacgaaat cattgggaat aaagattaca
     4381 ctggtatccg ttatgacgac actttccgta acatcgtagg tatggaagaa tatcatgatg
     4441 gaagtgccga cacaatctcc ggaatcaaaa aaatagacga caaaacagtt gaaatcgaat
     4501 ataaagaagt aaacccaagc atgcttcaat cgggtggtgg tatctggtca tatgcagcac
     4561 caaaacatac gttagaaggt gtagcaatca aagatatgga atcaagcgat caagtacgta
     4621 aaaatccagt gacttttggc ccttattaca tgagtaatat cgttgcagga gaatcagtag
     4681 aatacttgcc aaacgagcac tactggaatg gtacgcctaa attgaaaaag atcacgatga
     4741 aatctgtacc gatggcaagt gcaactgaag cattgaactc taaattatat gatatgattt
     4801 tccaaatgcc aacagatact tacgatacct ataaagaaat tgctggctat acaaacttag
     4861 gccgtgaaca aacttcttat acttatctag gattcaagtt aggtaaatgg aatgcagata
     4921 caaagagtgt ggaatacaat ccagattcaa aaatggctga taaatcatta cgtcaagcaa
     4981 tgggctatgc attagataat aatgcagtag gtgaacgttt ctatgcaggt ttgagaagca
     5041 atgcgacttc attgattcct ccagtattcc agtcatacca tgatgatgag atgaaaggat
     5101 tcacacaaga tctagacaaa gcgaaaaaac tattagatga tgctggctac aaagatgtgg
     5161 atgacgatgg tttaagagaa gacaaagatg gaaataaact aacaatcaac tttgcttcga
     5221 tgtccggtgg ggaaacagcg caaccattgg cagattacta tatccaacaa tggaaagaaa
     5281 ttggtttgga tgtccaatac acaacaggtc gtctgatcga attcaattct ttctatgata
     5341 aattagaaaa cgatgatcct gaaattgatg tttaccaagc tgcttggaat acaggaactg
     5401 atccaaatcc aagtggacta tggggaccaa atgctgcgtt caactacact cgttatgaat
     5461 cagaagaaaa tacaaaattg atcaacgata tcagttcaag caaagcattt gatgaagagt
     5521 accaaaaaga agcatatcaa aaatggcaac aatatgcatt tgaagaagca tttgcgattc
     5581 caacgttgtt ccgtaatgaa gtattgccag tcaacgaccg tgtcaaagac tgggattggt
     5641 cttatgatgt accaaaccca tgggcaaatg tttctgttac agcagattca cgttcataat
     5701 cactaaaaat gaccgaaaaa gggcgatgtc ctttttcggt tttttgatat ttttctgttt
     5761 atttctctaa tattcaggtc aaggcgctga tttcatgact tctccaataa acggtgttca
     5821 aagtccagtt tctcggtatt aagtcaaatt tatgcaaaaa tatggaaagc cattttcaca
     5881 aaattttttc ttcatactcg aaactaaacg aatttttcac aacttctcgt caatcactag
     5941 gattattaaa gctttactta ccttttgacc gaaccatttc aaatttgaca aaaaaccagt
     6001 ataataagga agtatcgaaa aaatatccat aaaaggaatg tggaaaatgg acaaccagct
     6061 gacaaaagaa ctaaaagaaa actataacat cgtttttcac gatctaaatt tgcttgaaca
     6121 agcttttacc cattcatcct atgtgaatga gcatcgcaat ctgcaattat cggataatga
     6181 gcgacttgaa tttttaggag atgccgtttt agaactgatg gtttctcagt atttattccg
     6241 tttatatcct catttgccag aaggaaaatt gacaaaaaca cgagctgcga tcgttcgcga
     6301 agacagcttg tcgaaatttg ccaaagaatg tcactttgat caatatgttt tgttgggcaa
     6361 gggagaagag aattcaggag gacgtacgcg accagcattg ctttgcgacc tattcgaagc
     6421 ttttttaggc gcgttatatc ttgaccaggg attcgacacg acccatgcat tcatcgaaaa
     6481 agtgattttt cctaaagtca aagcaggtgc tttttcacat gagatggatc ataaaacaaa
     6541 actacaagaa gtcttgcaaa aatcaggtga tgtatcaatc gaataccgat tgatcaatga
     6601 agaaggtcca gctcatgaac gagtattttg gatcgaagtt tatgtagatg atcaattgat
     6661 tggcactgga caagggaaat cgaaaaaatt agcagaacaa gctgcggcgg aaaatgcatt
     6721 ggcagcactg taaaagtaag tgagggaaag ctttgtattt gaaacgaatt gaaatagccg
     6781 gttttaaatc atttgcagac aagacagtca ttgattttga aaatagcgtc acagcagtgg
     6841 ttggaccaaa tggcagcgga aaaagcaata ttacagaggc tatccgctgg gtattaggag
     6901 aacaatctgc taaaagtctg cgaggcggaa aaatgccgga tatcatcttt gccggttccg
     6961 atacccgtaa gcagctgaat attgcagaag tcacagtgat tttagacaat agtgatcatt
     7021 atctgccatt ggagtacaat gagatcagtg taacccgccg ttatcgacgg actggggaaa
     7081 gcgagttttt catcaataaa caaagctgca gattaaaaga tatccaagaa ttgttcttag
     7141 attctggatt aggaaaagaa tcgttctcaa tcatttctca aggaaaagta gaagcgattt
     7201 tcagtagtaa accggaagac cgtcgtggga tctttgaaga agcagctggt gtcttgaaat
     7261 acaagcagcg gaaaaagaaa gcagaacaga agctttttga aacagaagac aacctcagcc
     7321 gcgtccaaga catcatccac gaattggaag aacagttaac tcctttggcc gcccagagtg
     7381 aggcagcaaa ggagttttta cggctaaaag aaacactgac tcaaaccgat gtctctttga
     7441 tggttgctga aatcaagaca gcaaaaaaag attgggacaa caaacaagca cagcttgcga
     7501 aattcaatct agaattaggc aaactatctg agtcgatcca agaacaagaa tccattttgg
     7561 cgaagcagcg taaagaaaat gcgcaagccg atcgtctgat cgaaaaaaat cagcaagtat
     7621 tattagatct ttcggaaaaa ctgaagcaga cagaaggaca aaaagatgtt ttgcaggagc
     7681 ggacaaagca tacacaaaaa agctcgcaag aatatcaaac ttcattagca gaagcacaaa
     7741 aaaaggttaa acattttgaa aagcttcaag aaagcttgat gaaagcagca gcagaaaaag
     7801 aaacagagat ccaaaaagct gaagcaaatc tcataaaaac acagcaagaa ttagaaaaat
     7861 accaaaaatc aacgaaagaa ttattggcag aattaagaga tcaatatgtt gatttgatgc
     7921 aagaacaagc agctgtagga aacgaactga agtatctaga acgtcaatat atacaagaaa
     7981 cagcaaaaag caagcagacg ttagccaagc aatcggaagt agaagcatca gtagaccgat
     8041 tgatcttaca aaaagaagaa ttgacacaaa agcaggcgca gctaaaatca tctttaactg
     8101 aaacaaaaga gaagttagaa atgatccaac aaaacgggaa aaagttccaa gaagcattag
     8161 caaaagaaca gcctaaaatg tatcaattaa tgaatcaagt ccagcagcta cgtgctcgta
     8221 agaaaagcct tcaagaaatc caagaaaact attttggttt ttaccaaggg gttcgattgg
     8281 tcttgcagca taaacagcag ctttcgggta ttgtcggagc agtggctgaa ctgatcgatg
     8341 ttcctgcaga tttcacgtta gctatcgaaa cagctttagg tggggcagcc cagcatgtca
     8401 tcgttgaaaa tgaaaaagat gctcggcaag ccatcacgta tttgaaacag caaagaggag
     8461 gaagagcaac attccttcca ctgacgacaa tcaaaccaag acaattaccg gctcatatat
     8521 tgacacaagc agcagctgta gaagggttta tagggattgc cagtgaacaa gtcagttatc
     8581 ccgatcaaat ccaaactgtg gttcaaaacc tgctaggaac gatcctttta gccaaagact
     8641 taactagtgc caatgcaatc gcgcaaacga tccgctatca atatcgagtg gtttccttag
     8701 aaggtgatgt gatgaatgcc ggaggatcca tgacaggtgg agcgaataaa cgaggaaacc
     8761 aaggcagttt gtttgtacaa aatcaagaat tgaaacagtt gactagtgaa tttgaagaag
     8821 cagataaaca actccaagca caagaaaaaa aagttcagga gctgcaacaa gaaacagctc
     8881 gtttagccga agaacaagaa gttttgcgta cacgaggcga acaattacgt tttgaagaac
     8941 aagaagcgac aaatcagcta caaaacatca taaatgaact tgaacgtttt gaaaaagaaa
     9001 agcaaatctc aacttttgag acacgtgaac tgcagcagtt tatcgaagat tacgaaaagc
     9061 aaacgaacga attgaaagac aaacaaacag atcttgaatc gcaacgacaa aaaatcgacg
     9121 aagaaatcaa atcgttaagt caagaaagcg accagatgga agccagaaga gcacaagtac
     9181 aaagtcaaaa agcacaagaa caagcagatc ttgctgtctt gaaagagcag tttaatcatc
     9241 tgcagatcca gctccgcggt gcccgagtcc aaaaagcaga ggcaaccgaa cgtcaagaag
     9301 cgatagaaaa gcagttggcg acattgacag cagacttttc tgatcatgaa gtcacagaag
     9361 aaagtttgga aaaacaaatt aacgaattat ctgctcagcg agaaacatta aaagccgagt
     9421 tggcaaaagc caaagagcag cgagatagaa ggcaaaagga gatcgataag cttgaagcag
     9481 tcttggcaga gcgtaatcgt gagcaaaaag cacgactgtc ggaacaatcc aaattagaag
     9541 tccaaaaaga ccgagctgaa atgattttag ataatcattt gacctatctg cagtcagaat
     9601 atcagctgac atttgagaaa gcttcccaag actatcaaga aacaaccgat atcgaagaca
     9661 gtagaacaaa ggtttcatcc ttaaaagaac agattgaaaa actgggacca gtaaacttaa
     9721 attcaatcga acaatacgaa caagtcagtg aaagacatac attcttagca acacagcgag
     9781 atgatctgtt agcagcgaaa aaccaattgt ttgaaacgat ggatgagatg gatgatgaag
     9841 tgcggacaag attcaaagaa gtatttgaag ctatccgtca agaattcaaa attgtctttc
     9901 caaatatgtt tggcggcggt aaagctgaat tagtactgac ggaaccaact gatttgctga
     9961 aaacaggtat tgagattgaa gtacaacctc ctggcaaaaa actgcaaagt ctaagtttgc
    10021 tttctggagg agaacgagca cttacagcca tcgcgttgct cttttccatt atccgtgtct
    10081 gtcctgttcc gttttgtatc ttagatgagg tagaagcagc gttagatgaa gccaacgtga
    10141 aacgttttgg tcgttacttg agcgatttcc aagatgacac acaatttatc gtagtcacac
    10201 accgcaaagg aacgatggtc gcagcagatg tactgtacgg agtgacgatg caggaatccg
    10261 gtgtatcaaa aatcgtttct gtacggatgg aagatatcaa tgaagaggcg aaaatcaacg
    10321 aaacgaaagt gtaggaacga aaatgatcaa attagtagca atcgatttgg acggtacatt
    10381 attaaatgaa caaaagctga tttcagatga gaataaacaa gcattagcac aagcaaaaca
    10441 gcaaggggtc aagatcgttc tatgtacagg acgcccctta gctgcgatgg cgcattatct
    10501 gcaagaatta ggactggtag atgaaggtga ctacagcatc actttcaacg gcggtttggt
    10561 acaaaaaaat gatactggtg aaatcatgga aaagaaagtg atggaagtat cagatatcca
    10621 acgcttatac aaactggctc agcaattgga tctgccacta gatgttttgt ctgacaatgt
    10681 ggttttacag ctgcctagtg ccccaaggaa gcaatccttg tacaatgtgt tgaataagct
    10741 gctgcaattc caaccagcgg atataagcga tattacagat gaatttgtgc ttaataaggc
    10801 agtaatcgct tatgaccaag aagaattaga tcctaaaatc aaagaaatac cagcagaatt
    10861 ccatgaaatg tatgagatca tcaaaacaag aagtatgctt ttggaattta tgccaaaagg
    10921 tgttacaaaa gcttatggta tttctttatt ggcaaaagat cttggtttga aacaagaaga
    10981 aatcatggcg atcggtgatg aggaaaatga tttaccgatg atccaatatg ctggactagg
    11041 cgtagcgatg gagaatgctg tgcctttcgt caaagaagca gcagatttcg tgacagccag
    11101 caatgaagaa aatggcgtag ccaaagtgat ccaaaaattt gtattagagt agggggagtc
    11161 aaatgggatt ttttgataaa atcaagcgtg cttttactgg cgaagagaaa acagaagaag
    11221 ttgaagtaca ggagaagtac gacaagggtt tagaaaagac gcgtaaaaca tttggtgaac
    11281 ggatgaatga gttgtttgcc aattttcgaa cagtcgatga agactttttt gaagaattag
    11341 aagaaacact tatcggtgca gatgtaggtt ttgaaacagc gatacgaatt accgaagcat
    11401 tacgtcaaga agtgaaactc agaaatgcga aaaaatcggc agaagtccaa aatgcgatca
    11461 tcgagaaact tgtggatctc tatgaagcgg aaggaatcaa tgaagtaaat gaactaaata
    11521 tccaagaaga cggactaaca gttattttgt ttgtcggtgt taatggtgta gggaaaacaa
    11581 caagtattgg taaacttgcc catcagttca aaaacgaagg taaaaaagta ttgatggcag
    11641 cagcagatac cttccgcgct ggagcaatcg accagttagt tgtctggggc gaacgcgctg
    11701 gtgttgaagt tgttcgtggc aatgcaggag gcgatccagc agctgtcgta ttcgatgctt
    11761 tggaaagagc aaagacagag caggcagatg ttttactagt tgatactgca ggccgactgc
    11821 aaaataaagt gaacttgatg aacgaattag aaaaaataaa acgagtaatc cagcgggaat
    11881 taccagaagc accccaagaa acacttcttg tattagatgc aaccactggt caaaacgcga
    11941 tggttcaagc aaaacaattc aaagaaacaa cagatgtgac cggtcttgtt ttgacaaaat
    12001 tagatggtac agcaaagggc ggtatcgtac ttgctatccg taatgaattg catttaccag
    12061 tgaaattggt cggtcttggt gaaggaatcg atgacttgga gccgtttgat ccaaatgatt
    12121 ttgtcgttgg attgttcaaa ggattactaa aagaagaata acccatgtct aaaaagcagg
    12181 agctgtgaca aaagttgcag ctccttgttt gaatgattgt ttttaacata gctgtgtttt
    12241 tgatgccttc atttttatac ttatttgtaa gcggttctca aacaatttcg ttctttttct
    12301 tagacttttt gattataatt agattcatat gaattggagg tcacttaatg atgaatttta
    12361 agcaattatt attgcatgtc aatgcgcgcc cttttatcga ccaagctcga tttggtatag
    12421 aacgggaagg acagcgggtt gatcttgcag gaaatctagc aaaaaccgat catccagcaa
    12481 tctttggcga tcgatcctat cacccctata tccaaacaga ttttagcgaa acacaaacag
    12541 agatgatcac ccctgttacc gattctattc ccgaattatt tcagtatctc gctgctgttt
    12601 atgatgtgac tgctcgttct ataccgaaag aagagatgat ctggccatta agtatgccac
    12661 ctgccttacc ggaaaaagac gaagagatca ttattgcaaa attaaaaaat ttcgaagatg
    12721 tcttgtatcg acgttattta gcaaaagaat acgggaagcg aaaacagatg gtaagcggta
    12781 ttcatttcaa ttttgaattt ggcgatgagt tgctaagaac attgttcagc catcaggaag
    12841 aatttcaaga tttttccgaa ttcaaaacag aactttattt gaaaacagcg agaaacttta
    12901 tgcgctatcg ctggatgatc acttatttat tcggtgcttc accaatgagt gagaagaact
    12961 actttttaga tgaatcacat ccgcaagaac ctgttcgcag tattcgcaac agtgcgctgg
    13021 gctatacgaa tcatccaaat gtgaaagttt cctatgcttc tatgaaacag tatttagcag
    13081 atatcgagcg aatgatcgaa gaagggaaac tttcggagga gaaagaattt tatacaccgc
    13141 ttcgtttccg aggcggaaag aaagtcgcag atttagcaac aacaggtgtt cgttatattg
    13201 aattgcggaa tatcgatttg aatccttatg caagattggg tatcaatcca gagcaagttc
    13261 ggttcttaca attattcctg atgtacatgt tatggacaga agaaaaagaa gactgtgacc
    13321 aatgggtagc agaaggtacg actcgaaata acaaagtagc actagaacaa ccatcagatc
    13381 aaacagaatt tcatcaagaa ggtagagaaa ttcttgaagg aatgaagcaa atgctggttg
    13441 aattggattg gttggattct ctttatttag tagaggaagc attgactcaa atggatcatc
    13501 ctgaacaaac gttagcagcg aaactctatc aagaagcaca gctatcgagt cagcaagaag
    13561 ttgctgtggc attgggacat caatattata aagaaagcca tgaacgtccc tatcagttgg
    13621 ccggttttcg cgaaatggaa ctttctactc agatatttat gttcgatgcc atccaaaaag
    13681 gtgtccaagt caaagtatta gatgagtcgg atcaattttt gcgtctgcaa ttccaagacc
    13741 atgtagaata tgtgaaaaat gcaaacatga caagtaagga cagctatatc gtcccactta
    13801 tcatggaaaa caaaacagta acgaaaaaag tcttaaaaga agctgggttc cgggtaccag
    13861 gaggcgcaga attttcatcc atggaagaag cggtaaaagc ttatccgaga tttgccgagc
    13921 aggcatttgt gatcaaacct aaatcaacca attacgggtt aggtatcacg attttcaagg
    13981 aaggagctag tctggaagat tatcaagcag gtttagccat tgcttttcgt gaagacagtt
    14041 cggttttagt agaagaattt atgccgggaa cggaatatcg tttctttgtg atcgacggag
    14101 aagtccaagc catcatgttg cgagtccctg ctaatgttat tggtgacagt atccgaacag
    14161 tgaaagaact tgttgaagaa aaaaatagtg accctttgcg tggaacgaat catcgtgcac
    14221 ctttagaatt gatccaatta ggtgaattag aacaattgat gttgaaagaa caagggttga
    14281 cgatcgaatc agttccccaa gccaatcaaa ttgtttatct aagggagaac tcaaatatca
    14341 gtacaggtgg tgattcgatc gatatgactg atgaattttc tgaagcttac aaaaaaatcg
    14401 ccgtttctgc ggtagaagca ctaggagcta agattagtgg tatcgatttg attataccag
    14461 ataaagaaat cgatcctaca actgataaaa aagcatatgg gatcatcgaa gcaaatttca
    14521 atccagccat gcatatgcat gtttatcctt ttgcaggaaa aggcagaaga ttgacgatga
    14581 atgtattgaa attgttatat cctgaagtat tttaaaagaa aaagcttttg acagattgtc
    14641 ctatttgatg tcaatctgat caaaagcttt ttttgcatgt aaaaatttat gtgttttttc
    14701 gttttaaaat aaacgatccc agaagctttt tttctttttt ggtttttctt tttcagctgg
    14761 cgaagagttt tcttctgggt attttttttc gatatcaatc acaggttcat ttactgcttc
    14821 ttttgctgtt aagagcaatc cgaattcctc aggatttgca gtgacgtaat cgttgactac
    14881 agtgaaacgg ctattgtttt tcgttgctag ctggatatat tggttttgga cagaaagggg
    14941 tagagcccca ttcaagagta tggaagcatc tggatgtttt ttgagttctt ttaaaaagtt
    15001 ttctttgttt tttggttgga tcatttcagc aacagtcata ctaagatagc agcgttccct
    15061 gaatgtccct aaatatttat gctgttcttc agggttcact aaaggtgtac cataaagtcc
    15121 cttatccaaa tggcttttta catcatcttg tgccataaaa aataccctcc ttcttctctt
    15181 tgtctttctt acgattatag catattccca ataataccta aaacatatga aaaagcggtt
    15241 gcttttgttc aacgattcac ttaaaataag aatgaaaatc attctcaatt agaaaggtgg
    15301 attggatgcg ctacggacga ctagtagcat tattagttat tttaagtagt atttcattgt
    15361 tcatcggagt atcgaatgta caattgtcag aactgctcca gttagatggg caaagcttac
    15421 aaatcttgct agtgactcgt ttgccacgaa cgatttgttt gatccttgtg ggagcgacca
    15481 gtagtatttg tgggttgatc atgcaacatt tgacccaaaa taaatttgtt tcaccaacga
    15541 ctgcgggcac gatggatagt gcgcgtttag gtattttagt ggctatgatt ttcctacctg
    15601 gtgcatcctt gattgtccga tccttgacag cattttgctt tgcttttgca ggaacattgc
    15661 tttttttatc ccttacgcga ttgttcctcc agaaaaatca attgatgctt ccgttgattg
    15721 gagtcatgtt agggaatatc attggttcag ttgctacttt ttttgcttat caattccagt
    15781 tggtacaaaa tatgacttca tggcttcaag ggaattttgc gactgtgata cgaggaaatt
    15841 atgagttatt gtatgctgtt gttccattgt tgctcttggt ttggctattt gcttaccgat
    15901 ttacgatcat tggtctgggc gaatcgtttg cagtaaatct gggaatagat taccagaaga
    15961 tgcagttttt aggcattggc ttagtatcat tggctagtgc agtcatgttg atcatggtag
    16021 gaagcattcc ttttatcgga gtgatcattc cgaatcttgt ctctagaata tatggagatc
    16081 aagtgcacaa aacaattggc gtaactgctt tagcaggtag tttgttctta gtattttgcg
    16141 atcttgtcgc tcgcgtgttg atttttcctt atgaaatacc agtcagtgtg atcgttggaa
    16201 tcatcggtgg ggctatcttc ctttatcttc tgataagggg acgacgatat gcttaaaaaa
    16261 aagccatcta tttttattgg tatgcttgtt cttgttttat ttgttacagg aatgtacttg
    16321 acgatccata catatggaaa ctggcatttt gcatgtgcat tgaggagtaa gaaaattttt
    16381 gcatttatcc ttgtctcgct agctgtcagc agtgccacaa tcagctttca gacaattacg
    16441 cataaccagt ttttgactcc ttcagtattg ggacttgagt cgttatatgt ccttgtccaa
    16501 acggtccttt tcttctttat cggaggagtg acgatgcttc agcagacagg tacagttttt
    16561 ttcttattga acgttgggct gatggtcggg ctgagtctat tgttattttt ctttcttttg
    16621 aaaaaaatga gagcgaatct ttttttatta ctgatgtcag ggatgatttt aggtacgctt
    16681 tttggtagtg tcagtacctt tttacaagtc atcatggatc cgaatgaata tgatttgctt
    16741 caaggcagat tatttgcaag ctttggcaat atccagagtc agtatctttt gcctgcttct
    16801 ttgatcatta tcggctgctg gtacctgtta tttcgatatc gacatgtgct agacgttttc
    16861 catctcggaa atgaacaagc agtaaacctc gggatagaca cagatcgttt tgaatttttg
    16921 attttatgtt gtgtcagtct tttgacaggg acatcaacgg ctcttgtggg tccagttact
    16981 tttttagggt ttattgtcgc aaatatcagt tatcgtgtct tttctactta tcgtcatggt
    17041 cagctattta tcggaagctt tctggtagct atgctgtttc tgacaggagg acagctcgca
    17101 gtagagcaga ttttcggctg gaatacaaca gtgagtgtcg tcgttgaatt tgtcggagga
    17161 atttattttg tcacaaaatt gattcgcgaa aggaagagta tcctatgatt gatttacaaa
    17221 aggtcaataa actgtaccat ggaaaatcag tggttaaaga tgtacagtta acgattcctg
    17281 aaaagaaatt gactgctttt atcggtccaa atggtgctgg aaagtcaacg gtgttgtcga
    17341 tgatcagtcg tttgatacca aaagatacag gtgaaatcta tttagaccat aacgaagtaa
    17401 aggcttggaa atccaatgaa ttagccaaaa aattatcgat cctacgacaa tcgaatgaaa
    17461 taaatgtcca aatcaccgtg aaagaattag tagaatttgg acgatttcct tatacgaaag
    17521 gaaaattgac gacaaaagac gaggaaatcg ttcaggaatc actggaacac cttgggttag
    17581 aagaaatagc ggatcaatcg attgacactc tttcaggcgg tcaactccaa cgtgcgtata
    17641 ttgcaatggt gctagcgcaa gacacggatt atattttact ggatgaacct ttgaacaatc
    17701 tagatatgaa ttttgcggtt caaatcatgc agattttaaa aaatttagta caagaaatcg
    17761 ggaaaacaat tgttattgtt cttcatgata tcaactttgc tgcaagttat gcagacgaaa
    17821 ttgttgcaat gaaagatgga cagttattta cgcaaggaac gacccaagaa atgataaaaa
    17881 aagatgtatt ggatgaatta tacgaaatgg acatacggat ttgtgagatt gaaggccgca
    17941 gattctgtct ttatttctaa aactaacatt aggagagaag agatgaaaaa attagtagta
    18001 ggtatcttga ttctagcatc atttggttta gcagcatgtg gaaatagcaa caacaccagt
    18061 caggcagaca caaaaaaaag cagcacacaa actgaaacta cattgacgat aacagatagt
    18121 aatggagacc aaatcgaggt gccaaataat ccagaaaaag tcgtcgtatt cgacaatggt
    18181 tctttagata cgatggatgc tcttggtgtt ggagataagg tagttggagc agctacaagc
    18241 agccttcctg agtatctttc atcctataaa aaagtagaat cagcaggtgg aataaaagaa
    18301 ccagacttag aaaaaattaa tcagcttcag ccagatctaa tcatcatttc tggccgacaa
    18361 agagattttc aaaaagatct aagtcaaatt gctccgacca ttttcctttc tttagatgcg
    18421 aaaaatccat gggaatcttt ccagcaaaat gtcactgctt taggggagat ctttggtaag
    18481 caagaagaag ctaaaactca attagaggaa ttatctagtg caatcgatca gacgaaaaag
    18541 aaagcagaag ctactgacaa aaaagcacta gtcacacttg tgaatgaagg gcaattatca
    18601 gcctacggat ctggttctag attcggtttc atccatgatt tatttggctt tgaacaagca
    18661 gatgatcaaa tcgaagcatc cactcacggt caaagtgttt cttatgaata tgtgctggaa
    18721 aaaaatccgg atatcttatt tgtagtagac agaacaaaag ctattggtgg agacgacagc
    18781 aaagatgata tttctgccaa tgaactggta gcacaaacga atgctggtaa aaatcagcag
    18841 atcatctccc ttgaaccaga tgtctggtat ttaagcgggg gcggtttaga atcaatgaaa
    18901 ctgatgatcg aagatgtgaa tcaagcattt aaatagcata aataacagag gattaaactc
    18961 tcatactatg taacaataat gtttcttaca ttcttaaata gcaagagcct atcctcaaag
    19021 aagttatcaa aaaccatccg taaaatcgta ttgatgattt tacggatggt ttttatttat
    19081 ttgagaaatc ttttttcaac gtgaattcat tatctacatc atacgggttg attctagaat
    19141 ggggagtggc aaaaaatagt gtgatccatt ttttcagcat caagatcgcc tcctttgatt
    19201 tgaatcaaag gtacaaagcg aaacttagat aaaacttaaa tttagatatt tttattttgt
    19261 accgatctct tctttaaacg atgttccatc tgctgcttct cggcaataag tccactagac
    19321 tagaaaatat gagaagctat tttctgtcca gcgttcttat tactcaaagc aaatcgcagt
    19381 tgtcacaatc tcttctaaac gatgttccat ctgctgcttc tcggcaataa gcccactaga
    19441 ctagaaaata tgagaagcta ttttctgtcc agcgttctta ttactcaaag caaatcgcag
    19501 ttgtcacaat ctcttctaaa caatgttcaa tcagctgacc ttcggtatta gctcaaagca
    19561 ctgatttcac aacctctatt taggcatgtg tctcagcaag cggttgatag ttgatgatct
    19621 gcatttttcg ataaaaatcg gcgggaagct tactccaccg ttttaataat tgatagaaat
    19681 aactctcttc tgctttgatt ttatactcgc ttaatatcaa tccaaaacta ttcgtttttt
    19741 ttgaagctaa ttttttataa atatccaatg ctttggtttt atcttcattg acaaagagtg
    19801 tttttacttc aatataagaa ccctcgatat tttgtgtttc ttcgataaaa tagatgtttt
    19861 ttatatattc cttcatagtg attcctccaa agaagtcttt tatttgataa gtttactcta
    19921 ccgaagagtt gttaataatc cgtgaacaaa aagtaattct ttttccaata gttgttaaag
    19981 gttttttatt ttttatagta ttttttgtta tttaagaaag gaataaggtt aaacaaataa
    20041 caggttgctt tttgggtctt tttccgttca agaaactgaa cgaagaaaag ggaaagttgt
    20101 ctcttttgtg ataagagaaa tcataataaa cgaatgactt actttccaat aaattgagaa
    20161 cagtcagaac cagacaaatt agttgcatct gatgaataaa gtgattattc tatgacatga
    20221 ggtgatacag atgaaattag aagtgacaaa agaagcacaa gaagtattga agaataaatt
    20281 agaagcagac gatcaacttt tattagatat cgaaaacggt gacggtccat ttgcagaaag
    20341 ccaagtcagt tgccaattgg atacggcatt tcgattgatc attgtcaaaa aagatacaca
    20401 aacagatcta agtctttatt ctgtagtggc tgatacacca gttggaccaa tcaaaatcaa
    20461 agacagtgca atactttaca tggatgatcc atccacactt gctttagaac caacttataa
    20521 tagtttacaa ttaaaaggac caagcggctt gagaaaaggc aacttgcaag ttgttcgaaa
    20581 agactagagg gataaaatgg gaaaattggc gatcatcagc gacctacatg tggacatcaa
    20641 taaattcggc gaatcagagc tgatgcagct ttggcaagtt ttgcaaaagc acaagatcac
    20701 tcggcttcat ctagccggag atacggctaa taaagtagac cgttgcctag ctgttgtcga
    20761 atttttcgtc aataaaggat tatctacgac atttcatttc ggcaatcacg agttggcaga
    20821 tgtgcccaat gaacagatga tggaccattt tccagaccca cattttttaa atgaacggta
    20881 tattgcttta aatgagcaga ccgttctttt agggatgaat ggctggtacg actatcagtt
    20941 ttccgaattg aaagattacg aggcaatcgt acgaatgaag cgtttgtatt ggtatgatcg
    21001 gttcatccag cgtgggaaaa cagatctcga ggtcaatgca gaaatgcttg cagctgcaaa
    21061 aaatttgcta gaccagctgg aagcaaaaaa acttgaggtg attttatcca ctcatttcgt
    21121 tcctaaacgg gcatttatca tgtatcaatc tgctccttat gagcgttgga acaaattaaa
    21181 tgcattttta ggatcagaat cattcggaga attacttgac cgttattcaa atatcaaaca
    21241 agtagttttt ggccatacgc atcgtcgctt tgaagataaa tccatcggtc acacgattta
    21301 cagctgcaga ccttttggtt attattatga atggcagctg acccgagatt ttgtcttgaa
    21361 agaacagttg ctagacagct atgatcctat gaaattacgt gtcctcttgc gtgcccatca
    21421 cccagctttt caggcctatc aaacacaaca tttgcaagag gaatttgaac aagcgatgac
    21481 aatcgttccg tattgagaca gcattagtaa tgtgtaaaag aaaatacctt gtaaaacata
    21541 aggataagta agagcagtag atccatttat cgtggatatg ctgctttttt tgcggaaaat
    21601 aatcagcgaa tgtttatttg atcggatgat ttgtaactcg cagagtacta gatgcaagcg
    21661 tgtattcttt ttttgaacga taatcacaaa aaaaaatata atatacattt tttatttaat
    21721 tataattaat attgattgaa gtctaggcag tcaagtcaca ttttgataga taggaggggg
    21781 acttacgaat tattttaaag gctatgacag ctgtatttct agattgtgtt tgcatcaagt
    21841 tgcaataaaa actagaaatc aaatcgggct gataatcatt tataactaat cgatacatag
    21901 gaccaaatat aggtctatgt tcttttattt cataagtatc gtaaaacaga attttgctat
    21961 ggattaatcc aatcgactga tatgtttagt aaataaagaa agaggaatgt caatgatgaa
    22021 aaaagaaatc gtattaacag cagcaatgat gttattcagc atggtagcaa gtacgacttt
    22081 tgtttctgca actgaagtat acccaaagga atataacaca gaaggaacga ttacatttga
    22141 agcaggagat gagggtgtaa ctcctcctgt tgatccagag aatcctgatc ccaataaacc
    22201 tgtcgatcca tcagatcctc caagccctgg aacaggaggg gcattatcga ttgattatgg
    22261 atcaaaattc aaatttggga ctcaaaaaat ttctactgcg gataaaacgt attatgcagc
    22321 tgctgatgtg atgaacgatg ggtctagaaa accgacatat gtccaagtga cagataggag
    22381 aagtacctta tctgggtgga aattaagtgt ctctcaacca gaacagttta aaactgccag
    22441 tggggatgaa ctagttggag cacagctgaa atttacgaaa gggcaggctg tttctttggt
    22501 tgatccaaca tatacgccgc aaacggtgaa ttctgaatta acgttgacac cgggaggaaa
    22561 caatacgtta gcaattaatg ctaaatcagg aacaggtgtg gggacttggg tctatcgatt
    22621 tggtgcaaat gaaaatgaaa atcaagatgc ggtacagctt tcggtacccg gtaaatctgt
    22681 caagttagcg caacaatatt ccactaaatt agtttggaca ttagaagata cacctaacaa
    22741 ctagtttact gaaaagaact gttaaaaata aatacgtagt catattgtct tgcgaggtaa
    22801 tcgagcaaaa attgtcaaag gctaggctaa atttgtttgg atacgaatag ttcatctagg
    22861 aatttaacga tcaggaggaa aagatatatt gaaaaagagg aggatcgtgc tcattttaag
    22921 cagtctctta gtgactaata tctttccgat catagggtac tctttggaat tgaatcagtt
    22981 ggagcatgga aatagaagag acgaagaaag caaactcact tcgacattcg acagtttaat
    23041 agaatccaac cagacacaag aaagcagtga ggatttaagt atttcgagta gtggagagac
    23101 cactgacaac gtagaagctg agggttcgga caaacaagga ctagaagatg caccaatttc
    23161 tgcggttgag ctgcctgacg atcccaatat tatttctatc gataaaattt ttcaaacacc
    23221 tatcggtact agcacgtcca tattggaaaa tgggaagtta ctgcagttga acccagcaga
    23281 aaggtctcaa agaggagcta tttggtcaaa taagaagatt agtttactct cggattttac
    23341 atttaaatct tatttatact taggaaatca acgagataga gcgggagatg gcatgacctt
    23401 tacattgact ggcgatccta gaatggctag taatcccagt caagttattg gatcgccagg
    23461 tatgggaatt ggctcatatt ctactcgttc tggccaacct tacattgcga atgcgctctc
    23521 gattgagttt gatacgtata aaaatagtgg ttcttctgat cgaatggatc gagagataac
    23581 tgctgataat agagggcatg gacatgtcgc ttttgtcacg cctaaaccaa ataataataa
    23641 ttattctgga gagcatactg gcgtgacggt agctcctaca tttctttcta atggcacatg
    23701 gcgcttgtta ataattaaat gggacgcgga gcaaagaagt cttacttatg atttggaagg
    23761 tgtcggtcac tcttctcgga ttatacctga tctcattagg cagtttggtt ctacagaagt
    23821 aaattggggg tttacttctt caacaggtac tttttttcaa gaaaatgctg tcgctgtcac
    23881 gcgacttcca tcgaatgtca catcaacagc tgatgtaaaa gtcaacgata gtgattatgg
    23941 ggccatcgct gaagctggag gaaacgataa gataactatc agaaatacat tgaaggtcga
    24001 gggggatttt cttgaatata agaaaatgca gactagtatc gacctcccac aagaattaac
    24061 tattcccgag catatcttga tcaatggaaa tcaaattgat gccaaagata tcttgataac
    24121 cggaaatcga gtcacgctaa atctgacaga ttattttatt gctggagata cgttaataat
    24181 cgaattggag acaactttgc aggaagtaat tcctgaaaaa gtactcacta tgcattttga
    24241 ataccttgaa aacgggaatt tgattgagca atcgaatgaa ataaacctaa agatcgcaaa
    24301 gctgaaggag atagatatcc atgtttatta taaagataaa gacagtcaga ttgatattgc
    24361 tgaaatgaaa acaatcactg ggaaaatagg agagaagtat aaagaaactc ctattgatat
    24421 tgaagggtat gtttttgact cggattcagc gaatacagaa ggcatcttct ccgaaaatac
    24481 agaggatatc tatttttatt acagaaaagg caaactttat ctctcaactg ctcctcaata
    24541 tgtcaatttt ggaaaacata aaatatccag tagaccatta agtgaattcg gacagttttc
    24601 aggtgggttg aaaattatag atgaacgggc ttttggaagt tggaaattac aattgaaaca
    24661 agagaaagtt cttacaaatg gagattttga gcttccagaa gctctttcct ttgttacctc
    24721 tgaaaataca acggttatag ggacatccgc tgttacgatt ttcgaaagtg atcaaaaggg
    24781 tgaaagcgat ttgtcctctc ttttagattc tacagctcat cgtggaatca gaatagatat
    24841 tcctgtagaa aaccaaagaa tcggaacctt tgaggggaaa ctatcttgga tacttgcaga
    24901 tgtcccagga aattaacagg aagagaagaa tataacaaaa ttattgagtt tcaagaaggg
    24961 cacaggtacc ataggctctt gtgtcccaca gagacaagat tttgttatag tcttctctta
    25021 catatgatta aaggagcgat tttcttgaga ccaaaacaac aattatttat aacactccta
    25081 gttattttag gggcactttt taacaatata tcagtgtcag ctagtgcatt taatttttca
    25141 gtgacgccga taacttcaga gaatcaaatc gacaagagaa aaacttactt cgatcttcaa
    25201 cttgatccgg atcaggaagt agaagtaaaa gcggaattga gaaatgatac agaaaaagaa
    25261 gtgaaaatcg atatttctgt gaatagcgca accaccaatt caaatgtgat ggttgaatac
    25321 ggaaaaaacg agattgaaaa agacatgagc ctgatctttg atctggtaga ttatgtgagc
    25381 tatccacaga tagtgacgct aaaacctaaa agtgtccaaa ccgttgcttt tcatgtcagg
    25441 atgccgaatg agcgatttga tggtgtattg gctggtggga tcacattcca agaaatccag
    25501 acggaaaagg accaaacaga aactaaggat caaagcttat cgattgagaa tgaatacacc
    25561 tatattattg ctttgttgat gcaacagaca ctgaacgaag ttgctccgaa ccttactctt
    25621 catgaagtta aaccagatca aatcaatgca agaaatgtca tcttagcaaa cgttcaaaat
    25681 gatcaaaaaa cctatatcaa tcaagtagtt attgaaacaa aaattacaaa aaaaggacat
    25741 tctgaagttt tatatcaaga ggaaaaagaa ggattgcaga ttgcgccgaa tacaaatttt
    25801 tcttttccaa ctgctttaaa tggtcaaccg ctaaccccag gtgaatatca ccttacaatg
    25861 actgttttag gaaatgaaaa tgaaaatgga aaattttcga gaaaaaaagg aaatactacg
    25921 atcaactata ccaatcaatg ggtatttgaa aaagatttta caatagacgg aaaagtagcc
    25981 aaggaattga acacgacgga tgttacgatt aaaaaagaca ataattggat ttatatctta
    26041 gtagcttcac ttttcttatt gtttatttta ttatgcatac ttttgtttgt tttgagaaaa
    26101 aaagaagaga aagaaaagta aggttaagat aacaaatagt aaatttttat tattgtagga
    26161 tggttgggct ctttttataa caatataaaa tataccattt tattaataaa aatgcatact
    26221 agtaaatgat ataattctaa taacaggttt gatcgcgaga aaggccaaat aaaacgctct
    26281 ccaaaatgtt aaaaaaaaga caggacgatg tatattatac aaacaagaat cgctgacaac
    26341 agtgactcgg atccaggaaa tcagttttat ccccagctag ttggtgaatg catggaaagt
    26401 aatatacgta gaaagagctg atgactaatg aattatgagt tttttttaag caaagaagat
    26461 cacagaagtt attcattact taaatattta gaagcaagct caaatttatc agagtcaata
    26521 tcgaatgttc aagaagagtt gtcgctatcg acatttctct tgaaaaaaac gatcgataag
    26581 ctgaaacatg atttacaaaa gttcgatcta gagaaaaatt tgcgagtaac cgtcagtgaa
    26641 ttggatatat gtctggaaat taatggaaaa tgttctagca aagctctgtt atctcgttat
    26701 ataacggatt ctttatctat gaaaatggta ttggctttct ttcaggaaaa atatatctca
    26761 gtagaaaatt ttgctaaaca gcatcacgtg agttattctg tggcttataa agtattacaa
    26821 agactaaaaa gaaatctaaa aaaatatcaa attttttttg aaaagagaaa gtt
//
LOCUS       DAXQKX010000034        25582 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.034, whole genome shotgun sequence.
ACCESSION   DAXQKX010000034 DAXQKX010000000
VERSION     DAXQKX010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25582)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25582)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25582
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.034"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..190
                     /locus_tag="ACF3MF_001626"
     CDS             <1..190
                     /locus_tag="ACF3MF_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927619.1"
                     /translation="WVYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIA
                     AIITQLFLVFGEKKRSKK"
     gene            complement(281..646)
                     /locus_tag="ACF3MF_001627"
     CDS             complement(281..646)
                     /locus_tag="ACF3MF_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927620.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            854..1336
                     /locus_tag="ACF3MF_001628"
     CDS             854..1336
                     /locus_tag="ACF3MF_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927621.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     LVVSRNFPALTVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDSAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            1533..2423
                     /locus_tag="ACF3MF_001629"
     CDS             1533..2423
                     /locus_tag="ACF3MF_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042301 - phosphate ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HFE3927622.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            2749..5223
                     /locus_tag="ACF3MF_001630"
     CDS             2749..5223
                     /locus_tag="ACF3MF_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFE3927623.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGHQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKVIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLLKRRNNTVAMTGDGVNDI
                     LAMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLV
                     KNIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNV
                     MEKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKF
                     RSQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLF
                     ERKNEKEQKPFSRVVKKFLSIFKREN"
     gene            complement(5326..7062)
                     /locus_tag="ACF3MF_001631"
     CDS             complement(5326..7062)
                     /locus_tag="ACF3MF_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFE3927624.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNGDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRAYTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLHGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(7059..7763)
                     /locus_tag="ACF3MF_001632"
     CDS             complement(7059..7763)
                     /locus_tag="ACF3MF_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFE3927625.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            7894..8397
                     /locus_tag="ACF3MF_001633"
     CDS             7894..8397
                     /locus_tag="ACF3MF_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HFE3927626.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            8357..8695
                     /locus_tag="ACF3MF_001634"
     CDS             8357..8695
                     /locus_tag="ACF3MF_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HFE3927627.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            8716..10134
                     /gene="ffh"
                     /locus_tag="ACF3MF_001635"
     CDS             8716..10134
                     /gene="ffh"
                     /locus_tag="ACF3MF_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HFE3927628.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            10246..10824
                     /locus_tag="ACF3MF_001636"
     CDS             10246..10824
                     /locus_tag="ACF3MF_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HFE3927629.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            10828..11349
                     /locus_tag="ACF3MF_001637"
     CDS             10828..11349
                     /locus_tag="ACF3MF_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HFE3927630.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(11428..11982)
                     /locus_tag="ACF3MF_001638"
     CDS             complement(11428..11982)
                     /locus_tag="ACF3MF_001638"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HFE3927631.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            12235..12510
                     /gene="rpsP"
                     /locus_tag="ACF3MF_001639"
     CDS             12235..12510
                     /gene="rpsP"
                     /locus_tag="ACF3MF_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HFE3927632.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            12522..12773
                     /locus_tag="ACF3MF_001640"
     CDS             12522..12773
                     /locus_tag="ACF3MF_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HFE3927633.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            12897..13688
                     /locus_tag="ACF3MF_001641"
     CDS             12897..13688
                     /locus_tag="ACF3MF_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927634.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTATTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            13858..14379
                     /gene="rimM"
                     /locus_tag="ACF3MF_001642"
     CDS             13858..14379
                     /gene="rimM"
                     /locus_tag="ACF3MF_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HFE3927635.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            14369..15130
                     /gene="trmD"
                     /locus_tag="ACF3MF_001643"
     CDS             14369..15130
                     /gene="trmD"
                     /locus_tag="ACF3MF_001643"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HFE3927636.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            15266..15613
                     /gene="rplS"
                     /locus_tag="ACF3MF_001644"
     CDS             15266..15613
                     /gene="rplS"
                     /locus_tag="ACF3MF_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HFE3927637.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            15923..16165
                     /locus_tag="ACF3MF_001645"
     CDS             15923..16165
                     /locus_tag="ACF3MF_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HFE3927638.1"
                     /translation="MNDGKVKQVPSSTKKKNILLKEVLKRFDHGVTYTETEVNSILLN
                     VFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            complement(16253..16399)
                     /locus_tag="ACF3MF_001646"
                     /pseudo
     CDS             complement(16253..16399)
                     /locus_tag="ACF3MF_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332517.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamate
                     endopeptidase"
     gene            16456..16770
                     /locus_tag="ACF3MF_001647"
                     /pseudo
     CDS             16456..16770
                     /locus_tag="ACF3MF_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345994.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronyl hydrolase"
     gene            16799..18058
                     /locus_tag="ACF3MF_001648"
     CDS             16799..18058
                     /locus_tag="ACF3MF_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFE3927639.1"
                     /translation="MKRWKKMMIGSIVLGMSLVFGACGNQEDSSEESANEITVSTWNY
                     ETTPEFKALFEAFEKKTGIKVKAVDIASDDYDTKLTTMLSSGDTTDVLTMKNLLSYSN
                     YALRDQLVDQTERIRELDTDAAEETYEMYDIDGKTYALPYRTDFWVLYYNKKMFDDAG
                     IEYPKNLTWDEYEDLAKKLSKNDGQVYGAYQHIWRSTIQAIAAAQNEANLVEPDYQYM
                     TDYYDRALRMQKEGAQMDFGTAKSTKVTYQSQFEEQKAAMMYMGTWYMAGILANKEAS
                     KTEVEWGITAIPQKKKGESVTTFGSPTAFAVNKNSKKQKAAQEFIEFAASEEGAKVLA
                     GVGVVPSYRTDEIDQLYFNLAGMPTDEISKKAFSPDEIKLEFPIDTYGPAIDKILQEE
                     YDLVLVGDETPEKGTVNMEKRVAAEKE"
     gene            18111..19007
                     /locus_tag="ACF3MF_001649"
     CDS             18111..19007
                     /locus_tag="ACF3MF_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFE3927640.1"
                     /translation="MENSINKKATNHLRRKRTWIAYSFIAPNFIGFFVFTLIPILFSL
                     VLAFMKWDSFSTPEFAGLDNFRKMANDETFWISLKNTFLYTAAVVPGTLVCSLGLALL
                     LNQKIRGMKLFRTIFFFPYVTSLVAIAVVWNMLFHPTVGPINIFLRRFIEHPPGWTSS
                     SNWALWAIVIVSIWRGMGYYMILYLAGLQSIQKELYEASSLDGANRWKQFLNVTLPSL
                     RPTTFFVTIMLVINCFKVFDLVQVMTDGGPGRATNVLVYQIYNEAFKKFDFGYASAIS
                     LVLFVIVLGVTVVQFSWNKRRT"
     gene            19018..19887
                     /locus_tag="ACF3MF_001650"
     CDS             19018..19887
                     /locus_tag="ACF3MF_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFE3927641.1"
                     /translation="MEESVRNERKKAKIRSKNMPFIQWLGMILLIVLALLTIIPFLWM
                     VSASFKANNEVLTIPIQWIPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFT
                     SSFAVYGFSELNFKGRDILFLAYIGTIAVPWQSYMIPQFIMMRKVGLTDTLWSLVLLQ
                     AFNAFGVFLLKQYYSSIPDSLCESARIDGLSEWEIYRKIILPLTKPAIASLTIITFVN
                     TWNDYMGPFIYLSSTENKTIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQK
                     YFVEGIASSGMKE"
     gene            19897..20572
                     /locus_tag="ACF3MF_001651"
                     /pseudo
     CDS             19897..20572
                     /locus_tag="ACF3MF_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
     gene            20778..22442
                     /gene="alsS"
                     /locus_tag="ACF3MF_001652"
     CDS             20778..22442
                     /gene="alsS"
                     /locus_tag="ACF3MF_001652"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0034077 - butanediol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HFE3927642.1"
                     /translation="MAEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVEKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAKLTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            22455..23165
                     /gene="budA"
                     /locus_tag="ACF3MF_001653"
     CDS             22455..23165
                     /gene="budA"
                     /locus_tag="ACF3MF_001653"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HFE3927643.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            23295..23792
                     /locus_tag="ACF3MF_001654"
     CDS             23295..23792
                     /locus_tag="ACF3MF_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HFE3927644.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            23977..24237
                     /locus_tag="ACF3MF_001655"
     CDS             23977..24237
                     /locus_tag="ACF3MF_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927645.1"
                     /translation="MNNETIILGKKYICEPIGLKQKVIGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(24599..24838)
                     /locus_tag="ACF3MF_001656"
     CDS             complement(24599..24838)
                     /locus_tag="ACF3MF_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927646.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            25124..25438
                     /locus_tag="ACF3MF_001657"
     CDS             25124..25438
                     /locus_tag="ACF3MF_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927647.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT         8486 a         4323 c         5250 g         7523 t
ORIGIN      
        1 ttgggtatac tcacaaacta ttttttatgg aggaattgtt ttaattagtt tactttcttc
       61 aacactttat tctttgaata ttatagatgt ttccacctca aattcaatat ctattattgg
      121 aatcattatt gctgcaatta ttacacaact gtttttagtg tttggagaga agaaaagaag
      181 taaaaaatag aaaaactagt gatagttttg gtgatataag aaaaacatat atgtataaaa
      241 agaagaaagt agcttctctt tgtacatata tggtttgttt ttatggatgc cgagcttttt
      301 tataagataa ggctaccgcc cataacgacc caaggatttg tggaactaag taaatacctg
      361 caagaagcaa gatcagctgg gtcggtttta aaggatgata gaagtaacgc cattcagtaa
      421 aattggcgca aaataaatag gaagtgacag tagatataat attggcaatg aataaagata
      481 taatacgcct gttcctttga aaataatatc cagcaaaaag agataaaaat atcaatgtga
      541 tgaacccgct tacggaatga taacgaaaat caagcagtaa ggcgaaatgc acataaggaa
      601 caaaagataa aagcaacgga aggtttttcc agcaagtttt tatcatcttt catcaccacc
      661 taacaagtgt tattattttg ttagttttat tgtaaattga atcctgcaat aatcaattac
      721 tttttcatta tttctagatt aaatgaataa actctcatgc cattatctct aaaaaaaaag
      781 tttttccccc taattttttt agatagaaaa ttgtatagta tgatgagaga aaaagtagtt
      841 tgggggaacg ttaatgagaa gaaaagcagt aatcgatcgg ctttatttat ttttttggtt
      901 ttttcctatc gttttgctac cttttacatg ggtaaatgct gttgtacaag gtgcggagat
      961 attaggcctg atccaaggaa gcggattagt ggtttctagg aattttccag ctttgactgt
     1021 tttctattta gtgataagtg taggtctctt attaccaaaa tctctgatca atcactacaa
     1081 ttggcagctg ctttactttt cttgcttatt agtatttaca tctatgtttt ctttgctgcc
     1141 tcgcttgatt atcggcccta atggtttgag cgagagtgga ttgaaggatt cagcttattc
     1201 ctccatgtat ttcttgacga tcaaaccatg gttctattta gtaattgcct catttattct
     1261 tgcaacattt ttttacttct ggacagaaat caggataaaa agtgaacgat ctgtatctat
     1321 aaaaaataac tattgatggt ggatcatcag taaaaaagca tatgagctgc gtaaaatgca
     1381 tgtttctcat atgctttttt tattattatg taaagaatgc gaaaaacgtt tacatgattt
     1441 ttacataact taactatatt tttacagcaa ccatacgagg gatttacagt cgactgataa
     1501 actttagttg taaataagaa aggagcaata aaatgaaaaa agtattgttt actctaggta
     1561 tgatgggaat tcttttagcc ggatgcggct caggatcagg aaatacagat ggctctgcca
     1621 cacaaaataa ttcaagtgac tcaaatgaac aagtaaaaat cgttgcggta ggttcgacag
     1681 cattacagcc gttagtcgat gcagcacaag aaagctttgt acaagaaaat ccaaattatc
     1741 aaatctctgt acaaggagga ggaagcggaa ctggtttgag ccaagtcgaa gctggagcag
     1801 ttactatcgg aaactctgat gtatttgcag aagaaagaga cggagttgat gcttcaaaat
     1861 tagtggatca taaagtagca gtggtcggga tggcaccaat cgtcaataaa gatacagatg
     1921 tcaaagatat caccaaacag gaattgattg atatctttac aggaaaaatc actaactgga
     1981 aggaagttgg cgggaaagat caaaaaatca acgtcgtgaa ccgtgcaaac ggcagcggta
     2041 cccgcgcgac attcgaaaaa tggggactgg atggtgctac ccctgtgcag tcccaagaac
     2101 aagattcatc aggaacagtt cggcagctgg taagtcaaac accaggagca atcagctatt
     2161 tagctttctc atatctcgat gattccacac aagcactaag tatcgacggt gtagaaccaa
     2221 aagaagagaa tgtagcagat aacagctggg gaatctggtc atatgaacat atgtacacga
     2281 acggaaaacc ttcccctgaa gtccaaaaat tcttagacta catgatgaca gaagaaatcc
     2341 aagaaggacc tgtcaaagaa ttgggctatt taccaatcac aatgatggaa gtagaacgtg
     2401 atcacgaagg aaatatcaaa taactagcag ataaacatgc cacggtagtc gttactatta
     2461 aggaaaaatc aactatgttt ccccacatat acatttttcc tttaattgtg aaaaatagtt
     2521 cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa caccgtttat
     2581 tcgaaaaaaa gagctacgac atagaactgt cgtagctttt tttttgctat atgacaggaa
     2641 tgaaaggtgt ttgcaagctt aatgtgagga acactttcca tatctgttct atactggata
     2701 ggagaagttt ggaaatatcc agaaaacgaa atcaatcgag gtagccacat gaagaataaa
     2761 tggataaatc gaagtaaaaa aaagaaagta acacaaagat catcagataa agtcatccgt
     2821 ctttttccat cgtataaaga aggattaacg gcagatcaag tcaaggaacg aatagaaaaa
     2881 ggtgcagcaa ataattcagt cgatcccaca ttcaaaacaa atcagcaaat cgtattggaa
     2941 aacatattta cgtatttcaa tttgatcttt cttatcttag ccattttgct ttgtttagta
     3001 gaatcctata agaacttgac ttttttacca gttatcatag ccaatacagg aatcgccatt
     3061 tttcaggaaa ttcgatccaa aaagatcttg gacgaactaa atgttttaaa tacagcaaaa
     3121 gtcaatgtca tacgagacgg gatagaacaa acaatagata tagaagacct tgtaatagat
     3181 gacattgtta ttttagagac tggacatcaa attccagcag atgcagaggt cgtggaaggg
     3241 aaactgcaag ttaatgaggc tttattgaca ggcgaagcag atgaaataac caaagaaata
     3301 ggcgatccat taatgtccgg cagtttcatt gtttccggaa aagcttacgc ccgattagac
     3361 aaagttggag cagattcgta tatttcccag ctgacagtca aagccaagac aatgggagaa
     3421 ggagaacagt cggagatgat tgcttctctt aatcaattga tcaaatggat tgggatcatc
     3481 attattccta tcggtatcct gcttttttct caaagttact tttttaatgg aaacacgatc
     3541 aaagaaagtg tcgttgcaat ggaagcagca ttgatcggta tgatacctga aggactgtac
     3601 ttgctgacga cgattgcatt agcattaagt gcgactaaac tagcaaagca aagagttctt
     3661 ttacacaata tgaaaagcat tgagacattg gcaagggtaa atgtcctttg tgtagataaa
     3721 acaggaacga tcacagaaaa taaaatgtct gttcaaaaag tgatcgtctc taaaaaacaa
     3781 gaaataatca gtcagtcaga tcaattggaa gcatgcattg ctgactatgc aaaagcgatg
     3841 gcaggagaca atgcaacaat ggaagctgtt aaagcatatt ttacaaaaac cactgatcaa
     3901 tcctatcacc atgttattcc tttttcttct gtccaaaaat tcagcagtgt agcgttggca
     3961 gacaaggtgt atgttttagg agcgcccgaa atggttttgc gcgatcaatt gccggaatat
     4021 gcggaagagt ttgtttcttt cgctgaaaaa ggctatcgcg tgttggtctt tggtgtgtac
     4081 gatgggattc ttgaagaacc agtattgaca gaagcagtca caccattagg ctatattctg
     4141 attgctaatc ctatcagaaa agaagcaaga gccacatttg attacttcaa aaaacagcaa
     4201 gtagccatca aagtgatttc tggagataat ccgctcaccg tatccaatgt agctgtccaa
     4261 gcagggattt cacatgctga tcagtacgtt gatgcatcta aattatcaga agaagaatat
     4321 gaagcagctg tcgaaaaata tacagttttt ggacgcgtca agccagaaca aaagaaaatc
     4381 ttcgttcaat tgctaaagcg tcgtaacaat acagtagcta tgacaggtga tggcgtgaat
     4441 gatattctag ccatgaaaga agcagactgc agtatagcga tggcttccgg aaatgaagcc
     4501 gccatgcagg cctcacaagt ggtcttactt gattctgact tttcacgcat gccagaagtt
     4561 gttgcagaag gacggcgcgt tgtgaacaat attgagcgat cagccagctt gtttttagtg
     4621 aagaatattt tctccttttt gctctcactg ttttcagtga tctttgctct gacctatcct
     4681 ttagaaccat cacaaatcac attgattagt ttgtttacta tcggacttcc atctttcttg
     4741 cttgctctag aagaaaacaa aaagcgaatc agagggaaat tcatcatgaa tgtgatggaa
     4801 aaagctgtgc caggtggact aacagatatg atcgtagtcg gtgcgttggt gatctgcggg
     4861 gtgactttga atctaaataa aacagatgtt tctacagcat ctaccatgct tttgattgca
     4921 gtagggttcc tcgttctcta taaaatctgt tcaccgctga ataaattcag aagtcagatc
     4981 attcttttct gtgctagcgg taactttttt tcggtcatct ttttgcataa gctgttttca
     5041 atcaccggta tctcagctgt atcacttttg ctgttgagca ttctattttt ctcggcagat
     5101 tcgattttta ggcatttgac cacattggta gaatatttgt ttgaacgtaa aaatgaaaaa
     5161 gagcaaaagc cgtttagtcg cgtagttaaa aaatttctat cgatatttaa acgagaaaat
     5221 tgacgaaaag tatctcaaaa aagagtaaaa aagaacaacc actcgtgtat ctttcgaagc
     5281 aggatgagtc atccaacttt aaaacgcacg agcagttgct cttttttaca ttttcggaat
     5341 ggtaacggtg aaagtcgaac ctgttccaag atgactgtct acagtaatcg taccatgaag
     5401 gagttgcacg tagtctttta caatcgctaa ccctaatccg gtcccgcctg aatgccggct
     5461 tcgcgccttg tctacgcggt aaaaacgctc aaagatccgt tcctgatcct caatgtcgat
     5521 acctatacca aagtcttgga cagaaaacga tagatcatct gttgcctgat agcggataat
     5581 aatctcgctg tcgctttttg aatattggac agcattttca atcagatttt tgataattgg
     5641 ataaaggata tctgttttag tagtaaatgg ttcgttcttt ccaatcaatc gaatcgtcaa
     5701 ccgtttcttt tcgatgattg gctgataatt ttgaacgatt tgctggaaat aaggttctgt
     5761 ataaattgtc tggatctcgt aagaattctc gccatctttt gacagctgga tgatttcccg
     5821 aatcagttta tctaaccgga tcgcatcttt ttgcatgatc tcaagaaaag aagtcagagt
     5881 ttgcgggtca tcttttgcac catccagtaa agtctcggta aaaccaatca gtgaagtcac
     5941 aggagttttt aattcgtgag agacgttgcc aacgaaatcc ttttgtagct tttctaaacg
     6001 tcgcactttc gttaagtcat acgccacccc tagaatctgt ccggtacctt ctgaattagt
     6061 aaagtagcgc aaactcaagt ctaatgtctg ccgaccttct gtaagggtga tctcctgatg
     6121 gatcagcgga tgctcaggag tcacttgatg aatcagctga atgagttttg gctcttgaat
     6181 gacttctgtg taccgctgtt caggttgata gcttaccacg tttaaatgta gctgcatctt
     6241 tggattaagc agtagtaaac gagaatcagc atcatcaatc aggaatacgc caatcatcag
     6301 ttcgttcagt aacgtatata attgctcttc tgtggtagta tacgcccgat acatcttact
     6361 catttgttcg ctcaacgcat tgatcgtctg atacaattct tcccattgat cgggtgtttg
     6421 catgattact tccgcctgat taggattttg caccattttt tttagtacgg gcagcacggt
     6481 tttcaatggc tggttttttt gatagatcag ataatagatc attcctgcaa gaacaaggaa
     6541 gaaagacaga aagaagaaaa agacccaacg gcgaaaactc tcagttctcg gtaaaaaacc
     6601 gcttgtcggt tctgcgatac gtaaaatggc ttctaactgg ccactttttt tgactggtaa
     6661 tgcgacatat aaaagatccc cattcaaagt agtacttttg cgcaaagcgc tacctaggtt
     6721 cccaccattc aatacggctt tgatttcggg acgggagttt cgctgttcat tcaatgtttc
     6781 attgtttgtg tcaaataaga tctttccagt agcatccatt aaagtaatcc gttcgttcga
     6841 ctgatggacg aattcttcca aagcagtttt gttttgcgct gcttggaggt tttcgacatc
     6901 taattgccgg atcagcagtt gtgctttttt tgtcaggtag ctttcttgct gttccacgat
     6961 ctgctgttga aaataatggg aaatcaattg ccagccacca aaaaacaaac taactaaaag
     7021 aataagaaag aagagacgtt cataaatttt tttccatttc atcgtttggg ttcctgaaac
     7081 ttatagccaa atcctctaat agtcaccaag tactttgggt gttttggatc tcgctcgatt
     7141 ttttctcgca aatgactaac gtgtacatct acgattcggc tttgtcctgc gaagtcaaaa
     7201 ttccaaatgc ggtctagcaa tgtgtctcgg tcgatcacac ggtcttttcg tttcatgaaa
     7261 taaacaagta attcaaattc tttcggtgtt agttcaatca gatggtcgtc tacggtcact
     7321 tgataattgg tcaaatcagc agtgatttgt ccaatcgata gatattcagg ctcagcttca
     7381 tcttttgatt gcttacgagg ttcaattcgt ctgaatattg ctttcatacg ggctaatact
     7441 tcgcgaggac taaatggttt ggtcaaatag tcgtcagcac ctatttctag gccaatgatc
     7501 cgatccactt ggtcatcttt agccgtcagc atcaaaatcg gtgtttcatt tttttcttga
     7561 cgcagccgct gagtgatctc catgccatcc atcgttggaa gcatcacatc taaaatgatg
     7621 aaatcaaatg attgttctaa tgctaattct aatccttcgc ctccatctgt ggcactggtt
     7681 accttgtagc cttctttttc caaattgaac gtcaagagcg ttacaataga aggttcatca
     7741 tcaacaacta gtattttttt cattcaaatc tcctttaaat aggtttcatt ctgtttatat
     7801 tttagcatag aatcagtaca aagggctatt ttacaaaaga aataaatggt ataataggaa
     7861 ggcactttgc tgaatagaaa ggaagagcag tcaatgattg gaatcagtgc atgtttaggc
     7921 ggtctggcct gtcgctatga tggacagaaa aaagaagtac cagaattgat ggaactagtt
     7981 gaaactggag aagctgtcat ggtctgtcca gaagtgatcg gcggattacc aattcctaga
     8041 gatcccgctg aaatcattgg tggaaatgga ttcgatgtgt ggaaagatca agcaaaagta
     8101 tggacgacaa gcggcgaaga tgtaacggaa gcgtacaaaa atggcgcgat caaagcctat
     8161 caaaaattgc aggaaaaaca cattgatcta gtcatcatga aggaaaaaag cccttcatgc
     8221 ggaacccatt cgatttatga cgggagtttt tccggaataa aaaaaaatgg tgccggagtg
     8281 gctactgctt attttattca gcaaaaaatg actgtgctct ctgatgaaga atggctgaaa
     8341 actagaggtg agcagaatgg aaatcgaaaa gaccaatcga atgaacgcgc tctttgaatt
     8401 ttattcgacc ttattgacag aaaaacaaat gaactacatg gaattatatt atgcagatga
     8461 tttttcatta ggtgagatcg cggaagaata cgaagtaagc cgacaagcag tatatgacaa
     8521 tatcaagcgg acaagcaaga tcttggagga ttatgaaaaa aaacttcatc ttttttctaa
     8581 ttatattgtt cgagaacagg tattggaaaa tatgactgca tatattacag ataagtaccc
     8641 ggaagataaa aaactacttg aatatgtaca gcaaattcaa gcaatcgaag aataaataaa
     8701 aggaatgaag aaaatatggc atttgaaagc ttaactgaac gtctccagca ggcgatggga
     8761 aaaataagaa aaaaaggaaa agtatcagaa gctgacgtaa aagaaatgat gcgggaaatc
     8821 cgccttgcct tactagaagc cgatgttaac ttgcaagtag tcaaagattt tactaagcgc
     8881 gtacgcgaac gtgcggtagg ggcagaagtg ctggaaagtt tatcacctgc acaacaaatc
     8941 gtaaaaatcg ttgatgaaga attgacgatc acacttggtt ctgaaacagc agagttaaat
     9001 aaatcaccaa aaataccaac tgttatcatg atggctggtc ttcaaggggc aggtaaaacg
     9061 acctttactg gtaaattagc caattattta aagaaaaatg aaaatgctcg tccgctccta
     9121 atcgcagggg acgtatatcg accagctgcg atcgaccaat tgaaagtatt aggtcaacag
     9181 ctagacgttc ctgtatttga tatgggaact gaagtcagcc cggtagagat cgtccgtcaa
     9241 gggatggagt tagcaaaaga aaagaaaaac gactatgtat tgatcgatac ggcaggacgt
     9301 ctgcatatcg atgaaacatt gatggatgag ttgaaacaaa tcaaagaatt gacgcaacca
     9361 aatgagattt tgcttgttgt cgatgccatg actggtcaag atgccgtcaa cgtagctgat
     9421 agcttcaacc agcaattagg tattacaggg gtcgtcatca ctaaacttga tggggatact
     9481 cgaggcgggg cagcactatc gatccgctca gtgacaggcg caccaatcaa attcatcggt
     9541 tctggtgaaa aattgactga cttagaagta ttccacccag atcgtatggc tagccgtatc
     9601 cttggtatgg gggatatgct gacattgatt gaaaaagcgc agcaagacta tgacgagaaa
     9661 aaagcggaag aacttgcaca gaaaatgcgg gaaaattcat tcgatttcaa tgactttatt
     9721 gaacagcttg atcaagtgat gggtatgggc ccactggaag atctaatcaa aatgatccca
     9781 ggaatgaatc aagtccctgg aatcgaaaac gtcaaggtag atccaaaaga tgttgaacgc
     9841 aaaaaagcga tggtttattc tatgacgcca gcagaaagag caaatcctga tctgttgaac
     9901 ccaagccgtc gtcgccgaat tgctgccggt tctggaaaca gtgttgttga agtgaatcga
     9961 atgatcaaac aattcaagga atcaagaaaa atgatgcagc aaatgtccaa aggggatatg
    10021 aacatcccag gtatggacca aatgtttggt tcaggcgtca aaggaaaact aggcaaaatg
    10081 gcgatgaatc gaatgatcaa gaaaaataag aagaaaaaga aaaaacggaa ataagatgaa
    10141 aaaaacagct tcggtacaga ctgaaaatgt ctactgccgg agcttttcta tcagcaattt
    10201 ttattcttta ctaatacaat tactctaaac gaagaggtgg cacagatgag atgtccgtgg
    10261 agtgaacaaa cagaaagtat gcggcaatat catgatactg tctggggtgt tcctgaatat
    10321 gatgaccaaa agctgttccg aaaattgatg cttgatatta atcaagccgg attgagctgg
    10381 cagacgattt taaataaaag tgaagcattc gatgaagcat atgatcgatt cgatattaaa
    10441 aaagtcgcaa attatggaga aacaaaaatc agtgaactaa tggaaaacaa aggaattatt
    10501 cgtaaccgaa gaaaaatcga agcagccgtc caaaacgcca aagcagtctt gaaaattcaa
    10561 gaagaaatcg gcagtttttc agagtatctt tggtcgtttt ctaatggaaa aatcgttgat
    10621 tcttcttatc attcacaaga agaagtccca acaacaagtc ctctttcaga tgaattagca
    10681 aaagatctaa agaaaagagg atttaaattt atcggaagca caacaatcta tgctttttta
    10741 gaagctgtcg ggatcatcaa tgatcacctt gacagttgtt tccgcaaaga agaggtcgta
    10801 cgtatcggca gaaagggcga ataaagcatg cgaaaaatca tattttatgg tgctataagt
    10861 ttagatggct atttggcaac gaaaacggat gatcttcaat ggctttttga cactccaaca
    10921 ggtaagcaaa ccacttatga agctttttat gaaacaatcg atacgaccat catgggcaga
    10981 aaaacttatc aggaagcaaa aaaatatttg gagaccgaag caatttatcc agagaaaaag
    11041 aatttcgttt tttccaccca cgcacaatta caattgccag atgctgaggt cgtaaacgaa
    11101 gatcctgttg cttttctaaa aaatctacaa atgacagaag gaaaagatat ctgggttgtg
    11161 ggtggcggtc gattgatcaa accgctattg gaacatcaaa tgattgatga atggtatatc
    11221 cagattaccc ctgtattatt aggggacggg attcctttat tccaaaaagg aacatatgaa
    11281 gcgcgttttg aaatgctaga cacgacacga ttcggtgaat ttatcgaatt gcattatgta
    11341 cgaaagtaga agtaaataaa ataaaaaagg caactatatg cagaaatgtc ctgtacatag
    11401 ttgccttttt tattaccgtt atgcttttta ctctgttaat ttgttagaaa aatctagata
    11461 cgcatctaaa atcgtttgga agaaacttaa tgttccttca acgatattac cattttcatc
    11521 aattagattc gcaacgtttc cgatatatgc ttccggttgc tgcaaggttg gcacattcaa
    11581 aaagacaagt gattgtcgta gatggtggtt tgcgccaaag ccgccgatcc cacctggtga
    11641 tgcagtaacg actaaacctg gtttatgatc ccaaacactg tgtccataag gtcttgagcc
    11701 tacatctaaa gcatttttca atactgctgg cacagaacgg ttgtattcag gagtaacgaa
    11761 aacgacaccg tctagtcccc tcacttcctc acgaaaacga gtccattcag caggagcctg
    11821 ttctggagtt tcgagatcct cattgtaaaa tggcagatca tcgattttta caaatacact
    11881 ttcgtaccct tcaggaagca atttcgcaaa agcttctgct acttttttgt tgtaagaatc
    11941 ttttcttaaa ctaccaataa aaaatccaat tttttttgtc atacgatttt tcctccttca
    12001 aactatctat aacaatctta caaaaaataa gtaactggag caaataaaaa cacttactga
    12061 caaaagctac atagaagata gattacttat ttttaacaaa aaagaagtct aaaatcttct
    12121 atttcctaaa aaaaatcgaa tttaatcaag ctgtaaagaa aaaaagcttt acagggtaaa
    12181 aaaaaactgt tacactacat cttgtgaata aaacaatgga ggtggaaata aataatggca
    12241 gttaaaatcc gtttaaaacg tatgggttct aaaaagagtc cgttttaccg tatcgtcgta
    12301 gctgattcac gttctcctcg tgatggacgt ttcatcgaaa ctgtaggtac ttacaatcct
    12361 ttgaaagacc ctgcagaagt agttttaaaa gaagacttag ttcttgactg gttatcaaaa
    12421 ggtgcacaac cttctgacac tgtacgtaac atcctttcaa aagaaggcgt tatgcaaaaa
    12481 caccacgaag ctaaattctc aaagaaataa ggtgaccgga tatgaaagat ttaagcgact
    12541 tagtcttaac aatcgttcgt ccgctagtca cttatcctga tcaagtcaag ttagacgtcg
    12601 tagagtcgaa agacttttac gagtacaatc taacagtggc tcctgaagat attggccgta
    12661 tcattggaaa acaagggcgt gttgctaaag caatccgcac aatcgtttac ggtgttcgga
    12721 tcaatgcacc gaaaaaagtg cgtttgaata tcatcgatga taaggaaaag taaataaacg
    12781 tgctgtactc gaattttcga gtgcagcttt tttgtttttt tattaattga agaaatgatt
    12841 atttggcaaa acaagcaaga aagcgtatcc ttataggagg agggagtgaa cagccaatga
    12901 gaaagaaaat gttatttatt ccatttgctc tattgttaag cgcttgtagt tcggttactc
    12961 aagaatcaga caatacacat ctatcaagca gtatatctga aactgttacc agtccagaaa
    13021 aaagtagtac caaaacggct accaccactg aacaaacaat ggctacctca aataatgaga
    13081 aaaagactgc tttagaccag ttgaaagaac aacagccaaa tgttcccatg cctctagatg
    13141 taccagtctc ttcaggctat ctcaatatcg cagcgacaca tacaaagcaa ggttattcta
    13201 ttttatatta cagaacagat cgtcccctcg ggttgaatgc tgacgaattg aatcaagaaa
    13261 cgcctattgc aacctatcta tatcaatatg ggtttgcttc tagtcaagaa acaatccaag
    13321 ttttgcagcc ctttgagatc gacacaaatg gtcagcaagt ggacttaggt tctcgaatca
    13381 cagggtatca gcaaggtgca gcaggttcaa gttttcttga atggcaagaa ggaaactggc
    13441 gtattcgaat ccgtgggaat aatatagaag gccaagatcc cttactatta gctaaagaaa
    13501 tcgtagctta tttggaagaa aacagtctac cagcacctga acaatttggt aaaattactg
    13561 ttgatatggg tgatacgacg aatcgagccg tagaagtaag ctggcaagaa ccgaaaaatg
    13621 cctatacgat cactcatcaa gatcctatgt ctgcgttgaa gatggcagtt tctatgaaga
    13681 ggttgtgaaa tcagcgcgct gatctgagcc catcatttaa ctccaagtca caggaagtaa
    13741 tcaaaaatag cacgccgcat ttttgcataa ttttggctta ataccttaaa agaaaactag
    13801 aattgcctct tcacacatgc taaaataaaa cagacaaaaa agaaatgggg atataagttg
    13861 actgaatact tgaatgtagg aaaaatcgta aacacacaag gtatcaaagg cgaagtccgt
    13921 gttatctcaa caacggattt cccagaagaa cgttacaaaa aaggaacggt gttaacacta
    13981 ttccaagacg gaaaagcacc tgtggaatta acagtcaaaa gtcatcgcaa acataaaaat
    14041 tttgacttat tgagttttga aggacatcct tctatcaatg atgtggaaaa atatcgggat
    14101 ggcatattaa aagtgtcaaa agacaactct gtagatctag ctgaaaatga attctattac
    14161 catgagatca tcggtctgca tgtattagaa gatggaactg agttaggtaa agtaaaagaa
    14221 atcttgtcac caggtgccaa tgatgtttgg gtcgttcaac gtccgaaaaa agctgatata
    14281 ttgcttccat atatcgcttc tgtcgtcaaa gaagtcgatt tagaagctgg agtggtccgt
    14341 gtagaaattc cagaaggact gattgacgat gaagattgat gtattgactt tatttccaag
    14401 aatgtttgaa ggtcctatgg gggaatccat catcggtaag gctgtagata aaggattatt
    14461 agatatcaat atctctaact tccgcgatta ttcagataac aaacatcaga cagtagatga
    14521 ttatccatac ggcggtggag caggtatgct gctcaaagtc cagcccatct atgataacat
    14581 ccaagccatt gaaaaagctg caccggatgt caaaaaaaga gtaattcttc ttgacccagc
    14641 tggtaaacga ttcgatcaga aaatggcaga agaattttca caagaagaac acttagtatt
    14701 catttgtggt cattatgagg gatatgatga acgtatccgc acattagtga cagatgaagt
    14761 ttccttagga gattatgtcc ttactggggg agaattaggt gcgatggtca tgatcgatgc
    14821 aacagttcgg cttttgccag atgtgttagg gaatcagact tcagctcaaa cggattctta
    14881 ttcaaccggt ttattggaac atccccaata tactcgcccg gcagaatata aagggatgaa
    14941 agtaccagaa gtattgacaa atggaaatca taaattgatt gaagaatggc aattaaaaga
    15001 atcactaaga aggacctatc aacgtcggcc tgatcttttg gaaacacttg aatggacacc
    15061 tcaaatgacg aaatttttag aagaaatcaa gaaagaagaa caagaaaaaa cagcagatga
    15121 agccaagtga ctttttctaa aatattcttt acagtaggtt gataatatgt tagtatttta
    15181 tggtgagtgc aaaagcactt aactattacg atattccgct atgagaaaag ctcataagaa
    15241 tatttggaat aaggagaaga aaaccatgaa tccattaatc gaagaattaa caaaagaaca
    15301 attacgttct gacatcccag cgttccgccc tggtgacact gtgcgtgttc acgcaaaagt
    15361 tgttgaaggt actcgtgaac gtatccagtt atttgaaggt gttgttatca aacgccgcgg
    15421 tgctggaatc agcgaaactt atacagtacg taaagtttct aacggagtgg gcgttgaacg
    15481 tacattccca ttgcatacac cacgtgttgc aaaaatcgaa gtagttcgct acggtaaagt
    15541 acgtcgtgca aaattgtact acctacgtgc attacacgga aaagctgctc gtatcaaaga
    15601 aatccgtcgt taatcattgt tatcagactg agaaagaacc cttggtattc aagggttctt
    15661 ttttcttagc atgtaatttg aacaccctga tccagttttt ttctttaatt attggtaggg
    15721 gagaataatg gattagaata aatctaccta taagtagtag taaaaaaaag agcactatga
    15781 taatatcttt cttaagagta accgctttaa taaaaaatcc agaatattct aacataaatg
    15841 gagtattctt agaatcaaaa ggagaaagaa gatggtttat acttatacgg agcaagaaaa
    15901 aatgaaagtt tgagacacat tcatgaatga tggaaaagta aaacaagtac caagttcaac
    15961 aaaaaagaaa aacatcctat tgaaagaagt cttgaaacgc tttgaccatg gagtgactta
    16021 tacagaaaca gaggttaatt cgatactgct gaacgtattt tctagtggcg attatgtcga
    16081 acaaagacgt tatctaatca catttggctt tttcaaaaga agttcagacg gtcgggcata
    16141 tcagatgatg ggaattgaaa attagaagtt ttaatttata ctcattgaaa aaagttcaag
    16201 tatgcgatat tggttctaca ccgcatactt gaactttttt tgtcatctgt atctataata
    16261 caaagccaag aacgttattc aaaatatgga tagctatgat aaaagctaat gagcgattcg
    16321 cagttaaata agcaatcgtc agtaaaatcg ttccaggagc gtacatgaaa aaatcaattg
    16381 gatgcgttac atgaataaag ataattctct tttatttgta cgaataaata ccaaaacgta
    16441 cctcctaaaa ttagattcaa agaagatagc aaagaggaaa aagatagttc tgcagcagct
    16501 atagcggcat gtggattgct agaactttcc aaacaactgc ctgtttcaga tcctcgtcat
    16561 ttcgattacg aagagatagc aatcaaaatc ttggaagaat tacagaaaaa ctatacaacg
    16621 aaacgagtta acggatcaaa cggtctgctt ctccatgccg tttatgataa aaacagctta
    16681 aaaggtgtag atgaatgtgt gatctggggc gattactttt atgtagaagg aatcactcgt
    16741 ctagctaaaa catggtactg ttactggtga tgtataagag aagaggagga ttcatataat
    16801 gaagcgatgg aaaaaaatga tgattggatc aatagtttta ggaatgtcac tcgtatttgg
    16861 tgcttgtggt aatcaagaag acagtagtga agaatcagca aatgaaatta ccgtttcgac
    16921 atggaattat gaaacaacac ctgaattcaa agcgctcttt gaagcattcg aaaagaaaac
    16981 gggaatcaaa gtgaaagcag tagatattgc ttcagatgat tatgatacga aactcaccac
    17041 gatgctttct tctggagaca cgacagatgt attgacgatg aaaaatcttt tgtcgtattc
    17101 aaattatgct ttacgagatc agttagtcga tcaaacagaa cgaattagag aattagacac
    17161 tgatgctgct gaagaaacat atgaaatgta tgatatcgat ggaaaaacat atgcattgcc
    17221 atatcgaacg gacttttggg tactatatta caataagaaa atgtttgatg atgcaggaat
    17281 cgaatatcca aaaaatctaa cttgggacga atatgaagat ttagcaaaaa aacttagtaa
    17341 aaatgacgga caagtttacg gagcatatca acatatctgg cgttcgacaa tccaagctat
    17401 tgcagctgct caaaacgagg cgaatcttgt tgaaccagat tatcaatata tgactgatta
    17461 ttatgatcga gcattgagga tgcaaaaaga aggcgcgcag atggattttg gcacggctaa
    17521 atcaacgaaa gtaacctatc agtctcaatt tgaagaacaa aaagcagcaa tgatgtacat
    17581 gggaacttgg tatatggctg gcatactcgc aaacaaagaa gcaagtaaga cagaagtaga
    17641 atggggaatt acagctattc ctcagaagaa aaaaggagaa tcggtcacga cgtttggctc
    17701 accaacagca tttgctgtca ataaaaactc aaagaaacaa aaagcggcgc aagaatttat
    17761 tgaatttgca gccagtgaag aaggagcaaa agtattagca ggagtaggag tagttccttc
    17821 atatcgtacg gatgagattg atcagcttta ttttaatctc gctggaatgc caacggatga
    17881 aatttctaaa aaagcttttt ctcctgatga aatcaaactt gaatttccga ttgatacgta
    17941 tgggcctgca atcgataaga ttttacaaga agaatatgac ttagttttgg ttggagatga
    18001 aacgccggaa aaaggaacgg taaatatgga gaaacgtgta gctgcggaaa aagaataatc
    18061 atgaaaggag agaagccaag agataaaaca ctcttggttt cgtcatcgaa atggagaata
    18121 gtataaataa gaaagctaca aatcatttgc gtagaaaacg aacgtggatc gcttattcgt
    18181 ttatcgcccc gaatttcatt ggttttttcg tttttacatt aataccaatc ctgttttcgc
    18241 ttgtactagc atttatgaaa tgggattctt tttcaacgcc agaatttgct ggactagata
    18301 actttcgtaa aatggccaac gatgagacat tttggatttc tttgaaaaat acttttttat
    18361 ataccgctgc tgtagtgcct ggcacacttg tttgttcgtt agggctagct ttactactaa
    18421 atcagaaaat tagagggatg aagctttttc gtacgatatt tttctttccg tatgttactt
    18481 ccttagtagc aattgctgtt gtttggaata tgttgtttca tccaacagtg ggacctatta
    18541 atatcttttt aagacgattt attgaacatc ctccaggttg gacttcaagt tcaaattggg
    18601 cgctttgggc aattgtaatt gtcagtattt ggcgagggat gggttattac atgattctat
    18661 accttgcagg actacaaagt atccaaaaag aactatatga agcgtcttcg ctagatggag
    18721 caaaccgttg gaaacaattt ttgaatgtga cattaccttc gttgagacca acaaccttct
    18781 ttgtaacgat catgcttgtc atcaattgtt tcaaggtgtt tgaccttgtg caagtgatga
    18841 cggatggcgg ccctggtcga gcgacaaatg tgctggttta ccaaatctac aatgaagcat
    18901 tcaaaaaatt tgattttggt tatgcttcag ctatttcact tgttttgttc gtaattgttt
    18961 tgggcgttac ggttgttcaa ttttcttgga ataagcgtcg tacttaggag gtgtgatatg
    19021 gaagagagtg ttcgaaatga aagaaaaaaa gcaaaaattc gttcaaaaaa catgcccttt
    19081 attcaatggt tgggtatgat tctgctgatt gtattagctt tattgacgat cattcctttt
    19141 ttatggatgg tttctgcttc attcaaagca aataatgaag tgttaacgat tccgattcaa
    19201 tggatcccta aaacttggca tttagagaat tatctggtta tttggtctcg tattccttta
    19261 gtgacatttt ttaagaatac agctttttta agcgttgtga tcacgttgat tcagttgttt
    19321 acttctagtt ttgctgttta cgggttttct gaactaaatt ttaaagggcg cgatatttta
    19381 tttttagcat atatcggcac gattgctgtc ccttggcagt cttatatgat cccgcagttc
    19441 attatgatga gaaaagtggg tttaacagat acgttgtggt cgttggtgct attacaagcg
    19501 ttcaatgctt ttggtgtgtt cttgttgaag caatattaca gtagtatccc agattcttta
    19561 tgtgagagtg cgcggatcga tggcttatca gagtgggaaa tctatcgcaa gatcatttta
    19621 cctcttacaa aaccggcgat tgccagtttg acgatcatca cattcgttaa tacatggaac
    19681 gattatatgg ggccattcat ttatttgtct tctacggaaa ataaaacaat ccagttaggg
    19741 ttgaaaatgt ttattgggct atttgatgca gagtacgcat taatcatggc tgcctcagtt
    19801 gtttctgttc ttcctgttgc ttttatattt ttagcgatgc aaaaatattt tgtagaaggg
    19861 atcgcttcat caggaatgaa ggaataggag gtgattatga aagagcagcg ttttgacaaa
    19921 aatgtttata tggaattctt ttattggttg tatcaatcat tggcaagtag cctttgtttt
    19981 tggtgtgtca atatcttgta tatagcagct gcgttccttt tgtcgataga tggaaggaat
    20041 gtcttttcct ttattttttc tttacttttt attggtccag gttgcatcgt gatgataggt
    20101 atgacagaag aattagcaaa agaaaaaagt ttttcaccag tacgtttgtt cataaagacg
    20161 tttcgccaat tttggctaaa gggatttttt tattggctat ttgcttggat agttagtgtg
    20221 ataatgattt ttgattgttt cttttttata cgtttttctt atggaaaatg gttgattccg
    20281 ttgtttgttt tacttgcttg ttttacttgc ttgtttatca gtttccttta gcatcaactg
    20341 ctggtatttt caggtgagaa atccagcgtc gaaaccaaat caagttctac ggatagcgtt
    20401 ctactatacg ttgaaaaaat ggtatgtgag tttactagat tttttactat tgacaagttt
    20461 gtttctcttc tttttcgtaa agccccaatg gtgtattcta ctaggtcctt ctatcgtatt
    20521 tggtttgatt tacttcaaca atcgtaaatt gatgagaact atggatctgt agactttata
    20581 aattgaaact ttcaattaag aatgacagtt ttttatgtaa aaactgtcat tctttttcat
    20641 tttttgaaac atatggctaa acaaatgaaa taaaacatgc tatacttttg aatgaaacag
    20701 gtttagaaac tgtatcactt atttgtgatt atttctaact aataattaaa aataaagcat
    20761 aaaaaggacg atgttcaatg gctgaaaaaa tgaaacaagg ttcgaaatct gtagtagaaa
    20821 gtttgattaa tcatcatgtt gattatgtat tcggtatacc aggtgcaaaa atcgatggtg
    20881 tatttaatga attagaggat caaggtcctg aattaatcgt gactcgtcac gaacaaaatg
    20941 ctgcatttat ggcacaagca atcggacgta ttacaggaga gccaggagta gttatcgcaa
    21001 caagtggtcc tggtgctagt aacttagcta caggtttggt aacagcgaca gcagaaggtg
    21061 acccagtttt agcaattgcc ggacaagtaa aacgaagcga tctattgaag ttgacccatc
    21121 aaagcatgga taatgcagca ctgttccagc caatcacaaa atacagtgca gaaatccaag
    21181 atccagaaac aatttcagaa gtgattgcca atgcttatcg tatggctaag agttcaaaaa
    21241 aaggcgcgag ctttatcagt atcccgcaag atgtagtgga tgcacctgtc caaggtaatg
    21301 tcatcaagcc attgagcgat cctaaattag gttctgcttc tgcagatgat atccgttacc
    21361 tagctgaacg cattagagaa gcaaaactac cggtactatt agtaggtatg cgaggatcaa
    21421 gtgaaaaaga aacgttagcc atcaggcaat tagttgaaaa gacagcattg cctgttgtag
    21481 agacattcca agcagctgga gtgatctcac gtgaattaga agcgcatttc tttggtcgtg
    21541 tgggtttatt tagaaaccaa ccaggagata tgcttttgaa acgaagtgat ctagttattg
    21601 caattggcta tgatccaatc gaatatgaag caagaaactg gaatgcggaa aaagatgcgc
    21661 ggatcattgt gatcgatgaa gcgccagctg aaatcgatcc ttttatgcag cctgaaagag
    21721 aattgatcgg tgatatctca gccactcttg atttattgac aggttcatta gagcctcaac
    21781 aagtgtcaga agatgcaaaa gaatatttag catctcttca agcaaaatta acggagcggg
    21841 acattgttca atcaaaagga gaagcaggta tcttgcatcc tttagaagtt attaacacgc
    21901 ttcagtcaaa agtaacagat gatatgactg ttaccgtaga tgtaggtagt cattatattt
    21961 ggatggcacg ccactttaga agttatgaac ctcgtcattt gttattcagt aatggtatgc
    22021 aaacgcttgg tgttgcattg ccatgggcga tttctgctgc attggtgcgt ccaaatacac
    22081 agatcgtatc agtttccggc gatgggggat ttttattctc tgcccaggat ttagaaacgg
    22141 cggtacgtaa aaaattgaat atcgttcatt tgatttggaa tgatggacac tacaatatgg
    22201 tagagttcca agaaaaaatg aaatatcagc gggcgtcagg tgtagacttt ggtccagttg
    22261 attttgtgaa atatgcagaa gcttttggcg ctaaaggaat ccgagctaca agtgtagagg
    22321 aattagaaaa agctttagaa gaaggatttg cgacagaagg acccgtaatt attgatattc
    22381 cgattgatta ccgtgataat gagaaattgg gagaaacaat cttaccagat caattctatt
    22441 aaggaagtgt cgacatgact gaaaaaatct tataccagca cgggacatta ggagctttga
    22501 tggccggctt gatggatgga acagaaacga ttgctcatat attagaaaaa ggaactctgg
    22561 gattgggaac attgcatggg cttgatggtg aagtcatctt tttagatggc gtagcttatc
    22621 aaggaagatc agatggctca gttgcccaat tagatggaag tgaacttacc ccctatgcag
    22681 caattacaga ttttacgcca gatactagtt tttctgtctc aaaaactgca gatggagaac
    22741 aattgaaaaa agacatatta gtaagagaag ccggggaaaa cctatttttg gcagtgaaga
    22801 taactggatt attcaaaaat atgcacatcc gtatcatgcc gaagcaagaa aaaccttaca
    22861 gaagactagc aaaaatttca gagtctcaac cagaattcca acaaagcaat gtccaaggaa
    22921 cattagtcgg gttctttacg cctgaattat tccaaggagt tgctgcagcg ggatttcacc
    22981 tgcattttat cgatgataca catacatttg gcggacatgt aatggatttt gaagtggctg
    23041 aaggaaaagt tgagattagc cgcatctcgt cccttgtaca gcattttcca gttgatgatc
    23101 cgacttttgt tcacgaaacg attgattatg ctgatttagc agcagaaatc caacaagcag
    23161 aatagaaaaa gacagcgaga tgcgttcaag gtgattaacc tgacgtatct cgtttttttg
    23221 aggagaaaac ctagcgttta caaaaaaact gagctataat cttctccata gatcaaaaag
    23281 gagcggtttt tatcatgtgg acagaaaaac agaaaaaaga tgcatacgaa attttattat
    23341 tacagcaaca aggattatta gaagcagaag ataactggtt agcaaattta gcaaattcat
    23401 ctgcattgtt gaatgagact ttgcctgaga ctgtctttgc aggatattat ttattcgatg
    23461 gtaatgaatt gattttagga ccgttccaag ggcgagtttc ttgcacacgt atcaagatgg
    23521 gaaaaggagt ttgtggagaa tcagctgaaa aacaagaaac attgatcgtt gatgatgtca
    23581 aaacccatgc aaattacatt tcctgcgatt cagccgcaca atcagaaatc gtagtgccaa
    23641 tggtaaaaga aggtaattta atcggtgttt tagatatcga ttgcggagta acgaaagggt
    23701 atgatgaaat cgatcaagca tttctagaaa aatatgtaga tcttttatta gcaaatttta
    23761 atataaatgc tttttcattt attaataact aaaatcgtct attgaaacaa aaaagaagag
    23821 aaatcaagaa taaaaagagc cggaaagaca gtgggcattt ctgtttttcg gtttttttat
    23881 ttttttataa aatcacaagt gttattgatt ttcataatca tattttaatg ttattatcat
    23941 tttaaataat gaaaaaacat taaggatgga tgaaatatga ataacgaaac tatcatttta
    24001 ggaaaaaaat atatttgcga acctattggc ttgaaacaaa aagtgattgg agaagtaatc
    24061 agtaaattag aaaattgtgt tgtgatctgc gtagacgaat atcatgacgt cgatcgcaat
    24121 gaaatattag aaaaatgcgg aaaagtagtg gcaaaatata ctcacgttta tgagttggaa
    24181 acaacagaat atctatataa ctatagcaac aaatatgaac atactttagt ttcataaaga
    24241 tttaaataaa gtgccttcaa aagcgagaag accaagcttt tgaaggcact ttatttagtt
    24301 ggcagtgatt gttcatgatt tttgatttat tcaaaaggtt cgcctagaga atctgtctct
    24361 gtaacgaggc ctggtggaga aactcgataa aaacctatac tgccagaact gtcctatttt
    24421 cggatagaca aactagtagt tttaaaaaga tcatccgatc caatcatttc aaaaaatgca
    24481 aaactgatat caggatcatt tagctcaggc ttgttatcgt aaagcatttg taaaggttgc
    24541 atttagttag gagtaaacgc gaaactatca tcattatttg ctgaagaaga tgaagaagct
    24601 aattcagagt ttgtttgaaa taaaggagac gtgctgacag tttctttacc ctgttttttg
    24661 cagaggtaga aacttttata tcggaagttt ctaccggaga atttttctca tttgtagaaa
    24721 ttgttgaatc gatactattc gaaatttgcg tatctgaagg tatgttcttt gatgcagaag
    24781 tcccacaagc agtaagtaac aataaatttg ataaactgat aaacagaatt cttttcatta
    24841 tgtacacact ccttatagta tcgtttagca tacacctatg ctcagtatta ggcaaaatca
    24901 atgcaaaact atcaagtctt ttatagtatc tattagtctt agtaatacat atatggagag
    24961 ggtgatatcc cagttcaaac cagatacatt ggttaccatc tgtattaacg attatgcctc
    25021 taaacgcttt ttttatgaaa aaatttataa gtgaaaacgt aggtatgata ttatctagag
    25081 gtaatttttt tgggtattta aatagttgct aggaggatag cttttggatt tttacagtaa
    25141 ttttatctta ataatagcaa tattattact tctaaatatt tggttttttg ataagagtag
    25201 aaatgcaggg ataggtttta gaaccaaacg aagtacgtct tctgaaaaaa agtgggtata
    25261 ttcacagact attttttacg gaggggttat ttcaatcagt ttactttctt caacacttta
    25321 ttcttttaat gttatagacg tttccatgtc aaattttata tctattattg gaatccttat
    25381 ttctgcaatt attacacaac tacttcttgt gtttgaagag aagtcaaaaa ataattaaag
    25441 caattatgcc ttttagtaca ggaattatta cttcttacaa atgtatagcg aatgtgaagc
    25501 ctgctgtttt aattgttcta gaaaaacttt tgagtgaaca attattttat gttaggatga
    25561 attaatttct ctagagttta ta
//
LOCUS       DAXQKX010000035        25352 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.035, whole genome shotgun sequence.
ACCESSION   DAXQKX010000035 DAXQKX010000000
VERSION     DAXQKX010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25352
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.035"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..527)
                     /locus_tag="ACF3MF_001658"
     CDS             complement(<1..527)
                     /locus_tag="ACF3MF_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927648.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFYFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPA"
     gene            854..1729
                     /locus_tag="ACF3MF_001659"
     CDS             854..1729
                     /locus_tag="ACF3MF_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010758089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFE3927649.1"
                     /translation="MGKRSTIQLMIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGT
                     FSRVQCTPDLLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLE
                     AMAENHATIDNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDD
                     ELLLLLDKFEKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAI
                     QLGISPRGSLSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKK
                     QIIHTLVAQIPIPVR"
     gene            1743..2066
                     /locus_tag="ACF3MF_001660"
     CDS             1743..2066
                     /locus_tag="ACF3MF_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927650.1"
                     /translation="MEKIKDYFINFVLFLVYFIIVLFALVFNNSLGWFLLAFFTLYVS
                     WSLISLSSFLKKLSVTCTLQPLVYRKKSMQVIFSIAKKRTFSLPLPRLQIGFPAIFAE
                     KNKRF"
     gene            2063..2815
                     /locus_tag="ACF3MF_001661"
     CDS             2063..2815
                     /locus_tag="ACF3MF_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HFE3927651.1"
                     /translation="MILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFRKSAKR
                     EISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNRIDWKL
                     SAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPELLILG
                     NRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIETLSKD
                     RTAYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            2805..4976
                     /locus_tag="ACF3MF_001662"
                     /pseudo
     CDS             2805..4976
                     /locus_tag="ACF3MF_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(5088..7259)
                     /gene="copB"
                     /locus_tag="ACF3MF_001663"
     CDS             complement(5088..7259)
                     /gene="copB"
                     /locus_tag="ACF3MF_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HFE3927652.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
     gene            complement(7279..9465)
                     /locus_tag="ACF3MF_001664"
     CDS             complement(7279..9465)
                     /locus_tag="ACF3MF_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFE3927653.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            complement(9465..9674)
                     /gene="copZ"
                     /locus_tag="ACF3MF_001665"
     CDS             complement(9465..9674)
                     /gene="copZ"
                     /locus_tag="ACF3MF_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HFE3927654.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(9687..10127)
                     /locus_tag="ACF3MF_001666"
     CDS             complement(9687..10127)
                     /locus_tag="ACF3MF_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HFE3927655.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(10201..10740)
                     /locus_tag="ACF3MF_001667"
     CDS             complement(10201..10740)
                     /locus_tag="ACF3MF_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HFE3927656.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            complement(11355..12821)
                     /locus_tag="ACF3MF_001668"
     CDS             complement(11355..12821)
                     /locus_tag="ACF3MF_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFE3927657.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            complement(13132..15213)
                     /locus_tag="ACF3MF_001669"
     CDS             complement(13132..15213)
                     /locus_tag="ACF3MF_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFE3927658.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            complement(15355..15477)
                     /locus_tag="ACF3MF_001670"
     CDS             complement(15355..15477)
                     /locus_tag="ACF3MF_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927659.1"
                     /translation="MNLDKLPATGFKLSCYPVKIKKASAGWIRAVAMIEKKKKE"
     gene            complement(15737..16096)
                     /locus_tag="ACF3MF_001671"
     CDS             complement(15737..16096)
                     /locus_tag="ACF3MF_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HFE3927660.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(16126..16467)
                     /locus_tag="ACF3MF_001672"
     CDS             complement(16126..16467)
                     /locus_tag="ACF3MF_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927661.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLILEAK
                     KRRIKSFFAQF"
     gene            complement(16464..17138)
                     /locus_tag="ACF3MF_001673"
     CDS             complement(16464..17138)
                     /locus_tag="ACF3MF_001673"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFE3927662.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTVGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIVYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(18191..19489)
                     /gene="asnS"
                     /locus_tag="ACF3MF_001674"
     CDS             complement(18191..19489)
                     /gene="asnS"
                     /locus_tag="ACF3MF_001674"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HFE3927663.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(19529..20719)
                     /locus_tag="ACF3MF_001675"
     CDS             complement(19529..20719)
                     /locus_tag="ACF3MF_001675"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFE3927664.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYSLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(20740..21267)
                     /locus_tag="ACF3MF_001676"
     CDS             complement(20740..21267)
                     /locus_tag="ACF3MF_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HFE3927665.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(21314..24103)
                     /locus_tag="ACF3MF_001677"
     CDS             complement(21314..24103)
                     /locus_tag="ACF3MF_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase C-terminal domain-containing protein"
                     /protein_id="HFE3927666.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(24250..24450)
                     /locus_tag="ACF3MF_001678"
     CDS             complement(24250..24450)
                     /locus_tag="ACF3MF_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFE3927667.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(24902..25222)
                     /locus_tag="ACF3MF_001679"
     CDS             complement(24902..25222)
                     /locus_tag="ACF3MF_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927668.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
BASE COUNT         7161 a         5400 c         4450 g         8341 t
ORIGIN      
        1 gccggatcct ttctttgctt caataattgg atgaacatct cagaaaagga ctgctctcca
       61 tcatctgcaa aaaaatgcgg aaaatctttc aaaaagtaaa acagcagata tcttactttt
      121 ctttctgaac caaagatctg tgctttttta taagaaaaag aaaggtggta ctcgccaaac
      181 cactttctca atcgctcttg cgtagaacga tcgtacttct gctcgtaagg ttcatttaat
      241 agcagatttt tcagtaaaca aaacgggggt gattggatca gaaaaacaaa caagagataa
      301 ggttcgctat atccttgatc ataaactaac tgaacggttt tcttatgaag aatcagctga
      361 atgggacagt cgctttccgc caaacgtttc agatgccgat ccactgtttt aacatcgatt
      421 ttcagttctt cagctaaatc agcttttcgc cagatcaaat ctttcattag attgattagt
      481 gaaaataaat tctgtgcatt ttttgataat agtttttgcc atctcatcga tcatttctca
      541 cctgatttct aaacatattg tttgatcaaa atgagttcac tcctaaaaag ataaaaaact
      601 ccctttctat ttatttaaat acgcaaatct tcctcattat tttttatttt actcaattta
      661 atcgtattct catttcaaaa cgaatgtact ttaaaaaaac ataataagat cactttgctt
      721 gtaggatgta ttcccttcca ttacaatgaa ataaatagcg attttatgag aaggtgatgt
      781 gaaaatggaa gaaaaaatag aagaatccaa acaaaaaatc gatcagttga tataagaatt
      841 agaaaaagcg gtcatcggca aacgttcaac tatccaattg atgatcgtgg ccctattagc
      901 aggtggtcat gtcttattcg aagatattcc cggtgtaggt aaaacgttac tggtcaaagc
      961 actagcaaaa gctgtacagg gaaccttcag cagagtccaa tgtactcctg atctgctgcc
     1021 tagtgatatt cttggttttt ccgtatacaa ttcacaatca aaagagtttg aatttcgtcc
     1081 gggaccgatc tttaccacga tcttgttggc agatgagatc aatcgtacga ctcctcgtac
     1141 tcagtcagca cttttagaag caatggccga gaatcatgca acgatcgaca acaatacata
     1201 ccctctagac aatcattttt ttgtcttagc tacgcaaaat ccaatcgagt acgaaggaac
     1261 atatcctttg ccggaagcac agctcgatcg ttttttattc cgactacaaa tcggttatcc
     1321 ttcttttgat gacgaacttt tgctactttt ggataaattc gaaaaagtgt tggataactt
     1381 aaatgaagta ttgaacagtt atgaaataga agaaataaaa acaaatgtgg cgaatgtctt
     1441 tgtcagtccc gaagtggcat cttatgcctt gcagttagtg tcagcaacaa gaagtcatgc
     1501 tgccatccag cttggcatca gtccacgagg aagcctttcc tttattcagg cagcaaaagc
     1561 ttatgcttta atccatggga gaaattacgt cacgcccaaa gatttgcagg atttagttcc
     1621 ttacgtgttt tcccatcgcc tgatttttta cgatcgttca ttgaaggaag acgaaaagaa
     1681 acaaatcatt catactcttg ttgcacaaat tcctattcct gtgaggtaga ttgaggtaga
     1741 caatggaaaa aatcaaagat tatttcatta attttgtgtt atttctggta tatttcatca
     1801 ttgtgctttt tgctcttgta ttcaacaatt ctttaggctg gttcttgttg gcctttttta
     1861 ctctttatgt atcatggagc ttgatttcat taagcagctt tctaaagaaa ctttcggtta
     1921 cttgtacatt gcagccactc gtttatcgca aaaaaagtat gcaggttatt ttttccatag
     1981 caaaaaagag aactttttct ttacctctcc ctcgtttaca aatcggcttc ccagcaatct
     2041 ttgcagaaaa aaacaagaga ttttgattct tacaaataaa ccgcaagaag tccaattgct
     2101 ttggcagcca aaagaaagag gatgccatga aacattaact gtcattttta cagcctatga
     2161 tagtctagga cttttcagaa aaagtgcaaa aagagagatc tcttttcctg tgactgttct
     2221 gcctgctttt tgtaagattc aagcagaaaa attacagaga gttctggaaa aaaaacagca
     2281 gctgaacgcg taccaaagag gtcttgattt tcgggaacat cgcgcttatc gtccaggtga
     2341 ttctttcaac cgaatcgatt ggaaattgtc tgctcatact caagagtggt tataccgtga
     2401 atacgattat caagaagaag aatgttctcc tcttttttgc ttttggggtt cgcccagtcc
     2461 aaaatttgaa cctctgctag acttgtattt ttctttatgg catttgagaa aagaaaagca
     2521 gccggaactt ctgatattag gcaaccgcgc ctttcatggc aaagaccccg gtcataccta
     2581 ttttgcttct ttggaagctg gcgatgagaa agcttttttc gcacacttga aaaaatatgc
     2641 aaaaaaacaa atcgtcctct ttgttcctga gaattctcct gaagtctcag aagctattga
     2701 aacattgtca aaagatcgaa cggcttatct tgtttatttc gtagaaaaac aactcatggt
     2761 ccaagaaaaa gacaagatat gttcattgcc aggaggtgaa tggattgacg attaaacggg
     2821 aaaaatggct gcgtggcgtt tactcctttg tgatactaag tgtaggtgct ccgatatttg
     2881 tagtagctaa tcaattgcaa aacagctacc ttcttatcct aactattggt gtcctatgcc
     2941 ttattgtctg ctgtattcct aaaaaatggg tacgtttgct gctttctttg ccagtaatga
     3001 taggttgttt gtttttatat tttccttcga agacattttc catattatgg atcttacagt
     3061 ttttttcgtc agttacagag gaattcttcc atctatccca aggtaaactt tattatttgc
     3121 cagaaaagac agcttttttt ctcataatgt tgctgatcta tttatttatt acattgaccg
     3181 tggattacga ctattggtac gcaccctttc tttctttgat ggcttacttc atgatgctta
     3241 ccgtttttcg gaaaaaagat ttactgtacg aaatgattgc ggtagtaact gttttgttcg
     3301 tgtatctggc agcaaggcaa tttttctcca tccggttgtt gtcgggaaac actcgattcc
     3361 agtcattgac tacagttctg cttatttgtt tcttaacttt tagcgctatc ttgcctttat
     3421 atcttccgaa agtacaccaa tctctcgagg aaacgagtga accgatccga gaatatctta
     3481 atgatgaagg gctttatgac acactccatg agtatcaatt aaccggaagt gcaagaacag
     3541 gcttcagtga gaatgatgaa cagcttggtg gacctttata tgataatggc gaagttgttt
     3601 ttacagcgaa ccaaaaagga aatggctatt ggaagatcga aaataaaaat cattacaccg
     3661 gttctggatg gatagaagat caggacgcac ccatccaacc aatccaagaa ttccctgttg
     3721 acatcacgag ctaccaaacc gttatagaag acaaagaaaa cattacattg accctaaaaa
     3781 aacaagcttt cttaccttat ccttatggaa atactacctt gactgatttt tcattagcta
     3841 gtggacaaac gctttactat ttgcctgaaa gccagcgatt cattcctgtc ccgaatgaat
     3901 cgacacgttc tgcaacttta caaacagaaa ggttagtttt tacgagagaa gaattaaaaa
     3961 gcagtcagtt aaaagctgat gatttagaaa atcagcagac aaatcttcaa ttgccaaaaa
     4021 gtttgcctaa acgtattgag gacttggcgg tcgaattgac caaaaatgaa gcaactttaa
     4081 ttcgtaaagt cgaagctgtc taacagtatt taaaaacaag cggaaatttc cgctattcca
     4141 aaacggatac cgggcatact ccgaaagaac acgattatgt ggattatttc ctctttgatt
     4201 caaaagtcgg ctattgtgac aacttttcaa cttctatggt cgtccttctt cgaacacttg
     4261 gtatcccagc tcgctggaca aaaggtttta caaatgggct cagaacaggc acagataatc
     4321 aagggaatga ggaatacagc attctcaata gtcatgctca ttcttggcca gaggtatact
     4381 ttcctggatt tggctggctt ccatttgaac caaccccttc atttgccaat ccaatgggtt
     4441 cacaaccagt tgctgaaaca accgaaaccg tccagcctgc tatcgaacaa ccaaatgaaa
     4501 gcgaaaatat ggcagaaact atttccagtg agagatctga ggtcattcca tcagaagaaa
     4561 caacactcac accagcttat aaaatcgtct tattcagcct tggagtgtgt ttatccgtct
     4621 tgttgttctt tctattgtta ttcagaaaat ctctgcgctg gacaagttat cttatctatc
     4681 ttcatttttt tgcttctact aatacgattg catatcaaaa acttcttaac cctttggaaa
     4741 cattggtacc gcgcaaaccc gcagaatctt tgcaggaata tagcctgcga atagaacaag
     4801 aattcaagct agatctgcgt ttcattcgat taactactca atatgaagca gaaatatatg
     4861 gacgacaagc agatccggta aaattcgata aaaaaaccta tttagaaata acgcgtataa
     4921 taagaaaaac ggtatacaaa aaaattctga caaaagggag ccgcttcaaa aaataagata
     4981 aaatttctgg agaatctact tctggaatgc cgagaaccag ctgattgagt atcgattact
     5041 cgaaaaaaag gttgtgacac gttttttgtc acaacctttt ttcattatta tttgattttc
     5101 aatgtcaaag catttagagc tacaactacc gtacttaacg acatcaagac agcaccaact
     5161 gctggactta atatgatacc aattggcgca agaattccgg ctgctagcgg aattgcaaga
     5221 atattgtaac ctgcccccca ccagaggttc tggatcattt tctttcgcgt ttgcttggct
     5281 agatcaagaa aatgcaaaat atcttttgga tcgctgtttg tcaatacgac atccgcagaa
     5341 tcgattgcga tatctgtccc tgcaccgatt gccatcccga ttgaagcacg ggctaaactt
     5401 ggcgcatcat tgatcccatc acccaccatg attacttttt tcccttggtc aaggtatttc
     5461 tggacaacag cttctttatc atctggtaat aaaccgccat aatattcttc gatccctaaa
     5521 taatctgcta ctgcttgggc agcgttttta ttgtcaccag taagcatgac aggagtgatt
     5581 tttctttctt tcaatgttcg gataaattct tttgcttctg tttttactac gtcacctaaa
     5641 gcaacgattg cagctagatg attttctaaa atcaggaagc tgatggtatt tccttgttct
     5701 tggtaaggtt tcaataatgc ttgttctacg tttaatccga gacgctcaac ttctttttca
     5761 ttaactattt tcacttgttg ttttttgact gttgcctcta gcccgactcc tgaaagattt
     5821 tttagatttt cagcttgata aggcttgatt tcatgttctt tcaaataatt cataatgcca
     5881 acagccaatg gatgattggc attcgcttcc aaggctccta gatattgaag gatttcattt
     5941 ttattgaacg catcatcaag tacttcgaca cccgttacag taaattttcc ttctgttagt
     6001 gttcctgttt tgtccagcat gatcacatct agatcattgg cttgctccag tgcattgcgg
     6061 tttttcaaaa gtaatccgtt tttagctgct attgatgtgg agcgagcaac aactaatggg
     6121 atagctaaac ctagagcatg aggacaggcg atgataaaga ctgttaccat acgttctaat
     6181 gcattaggaa gatctgtcaa gaacaaccag gcgatgaatg ccaggatacc cacaattaat
     6241 gcgacataaa acagccattt tgccactttg tcagataatg actctagctt ggatttttct
     6301 ccttgtgctt ttcgcaccat ttccataacc ttcgctagat aaccattttc accagttcca
     6361 gttacttcga tttcgatcgt tccatcccca ttgatagaac cgccaatcac tttgtcattg
     6421 gcttgttttt tgattcctct tgattcgcca gtcacagctg attcgtcaac aattgtttca
     6481 cctttcaaga ttacaccatc tgttggcatt ttatcaccag accggacgat caaacgatca
     6541 ccttcgttta cttctttcaa tgaaactgtc tcttcttttc catctttcgt caagcgtttc
     6601 actgattctg gcagtaattc tgctagtttt tgtaaagcat tgctggcatt cgacacagca
     6661 ttcatttcaa tccagtgacc tagtagcata ataacgatca aagtagccaa ttcccagaag
     6721 aaatccatga cgtgtgtatg tggattgagc agatttgcga taaacgaata gacactataa
     6781 atatatgcaa ctgtaatccc catcgcgatc agtgtcatca tagcaggact tttttgtttc
     6841 aattccatct tagctccact taaaaatggc tgaccgccat agataaatag tatagttgct
     6901 aagatcaata cgagccaatc agaaccagga aacgttactt gaaatggaaa ttccattccc
     6961 atcattggtg aaaaaagaat gattgggata gctaggataa gcgatagcca aaatttttgt
     7021 ttgaaattcc ccatgtgcat ggaatgatcc atgccgccgt gttcgtgatc catgtgcatc
     7081 gaatggtcca tttgtttgct gtttgctata tctccatggt tatgtcccat gtgcatggaa
     7141 tgatccatct gactatggtc atgtttcatc tccatctgtt tttcatgaga ttctgtactt
     7201 tctttgttta ctacttcttt tttatgctca tgttttttct ccatatcgtt cccattcatt
     7261 tttactccat cccttctctt actttttcat gtgtcgattt aagctcaggg agttcaacaa
     7321 tacactgacg gaactaaacg ccatcgctcc tcctgcaatg attggattca aaaagcctag
     7381 tgcggcaaaa ggaataccaa tcgtattata gacaaaagcc cagaaaagat tttgtttgat
     7441 ttttctcaat gtcaacctag acaactcgat tgtttgtgca atggatgcca aactgctatt
     7501 catcagcgtc acatcggctg tttccatcgc aatgtccgtt ccacttccca ttgccatacc
     7561 gacatcagct aatgctaagg ccggtgcatc attgattcca tcgcctgcca taccgacttt
     7621 tttgccatct ttctgaagtt tttctacgta ggctgcttta tcctctggaa gtacttcagc
     7681 aaagatatgc tttggatcaa taccaacttg tttaccaatc gtttcggctg ccagtttgtt
     7741 gtctcctgtc agcataaaaa catctaatcc tttattctgg agctgcttga ttgcttgttt
     7801 ggcttctagt ttgatttgat cagccacggc aatccacccg atcacttgct tttcatcagc
     7861 taaaaacatg actgtttttc cctgctgttc taattctaac gcgtgttctt ggtattcatc
     7921 aaatgatagg ttcaattcaa ttaatcgttt acgtgtaccc gcaaaatagc gtactccatt
     7981 aatcgtaccg ctgatcccag cacctgggtg ggctgtaaaa tcaatcatat cgtatgttgc
     8041 tgcttcttgc agttttccgt attccacgat tgctttacct agtggatgtt cagaagcttg
     8101 ttctaaagta taaaaaatag ataggacttc ttttgaaccg actagatctg taactttggg
     8161 ctttccttct gtaatcgttc cagttttatc caaaacaatg ctgtctaagt gagcagctgc
     8221 ttctaatgct tctccgcctt taattaaaat tccatttcgt gcaccaacac ccgttcctac
     8281 cataatagct gttggggtcg ctaaacctaa tgcacatgga cacgcaatga ctaatacaga
     8341 gacactatgg atcaatgcga gttgccaatc accagtgatc aaacctgtag ctatgagcgt
     8401 gataaacgcg atgactaata cgatcggaac aaaaatccct gagatccgat ctgcgatttt
     8461 ttggattggg gctttgctcc cttgagcatc ttccaccatt tgaatgattt gcgctaatac
     8521 tgtctgcttg ccgacttgtg tgacttccat gtgtagcaga ccattcgtat tgattgtccc
     8581 gccaaaaagc gtgtcatccg gattcttttc tacaggaaga ttttcaccag taagcatact
     8641 ttcatctatc gcactgcttc ctgaaataat tcgaccatct gctggaatct gctcaccagg
     8701 acggatgact agttgatcac caacgactac ttcttcaatc gctaacgttt cttctttccc
     8761 gtttcttatc acttgggcgg tttttgtttg aagagacatc aattgtttga ttgcattacc
     8821 tgttttcgtt tttgctgtat gttccaaata tttgccgagc aaaatcagcg tgatgatcat
     8881 actgctgctt tcaaaataaa gatcttgggg gtgtccacgg aaaaatccgt tgtaaatgct
     8941 caatgcaaag gcagccgatg ttccaattgc taccaataca tccatatttg gtgctttcgt
     9001 cttgattgca tggtacgcac ctttataaaa acgagcaccg acataaaatt ggacaggagc
     9061 agacagcact aactggacga ttggaaaatg aaaaaagtga acaatcgccg catggcttcc
     9121 taacatcata gcaatcattg acaacatcaa cggcaaagtc aaaaccgtac tcaatataag
     9181 atcgaatagc atttttttca aatacgcttg cttttcttct gcaatttttt gtttgtgggc
     9241 ttcatcgtac aaaattgcac cataaccgat gttttctacg ctttggatta atttttcagt
     9301 ggtcgtccct tcatatttga cacttgcttt ttcagtggcc aagttgactg tggcattgac
     9361 cacaccaggt tgtccgttca gctctttttc gatcctagca gaacaatttg cacaagtcat
     9421 acctgtaatg acgaacgtat ccattttggt ttctgctgtt gccatcaaat cacctctgct
     9481 ttataaccca atccattgat tgcttgacaa atcttttcgg attgaacttt tgtttcatca
     9541 aacttgaccg taccgtttgc ttttttcaaa tttactttca ctttttgcac gccgtcaagt
     9601 gcgcttactg tttcttctac tcttgctgca caatgattgc agctcatacc ttcgattgaa
     9661 aattgttgtt tcattttttc ttcctcctat tgatgttgtt tacattcaca ttgacctggg
     9721 atacagttac attcgatcgt atctactggt tgcttttgtt ccagttgttt caaaatctca
     9781 ttgatatctt cttgagtcaa agtggcttct tctactagat ccgcaatcgt ctctccaatc
     9841 ctttttgcac agatatggga aaaaagattt tccgtcgcac tgcgaactgt ttccatctcc
     9901 gagacagctg gatgataaat gaattttttt ccttcttgtt ctgtccagat cacttctttt
     9961 tttaccaaac gtcccagcaa agttttgatc gttgctggtt tccaatccat cgaatcagct
    10021 aagatctgcg tgatttcttg ggctgtcgtc tgtccaagtg tccaaataac acgcatgatc
    10081 tcccactctg aatcactgat ctttactggc gttttgactt tttccattta tttcacacct
    10141 ttcgtttaca aatgtaatca ttagcttatg aatacagatt acgcttgtaa acaaaaactg
    10201 tcaattattt ttgctctcta ttttcaattt agttaaaaat tcttgtttct ctcgtcttgt
    10261 tttaaggatg atcagtttat ttcttgcatt agctacttgg atcagctgct gtattttcgg
    10321 ttcattgttt tcttcaaaat gccagataaa agataaaaat tctaagtatt ccctgtttag
    10381 tttctctgaa aatgattcag gcatatctgg ccgagatttt ttgtttatct ttctttttag
    10441 agaacgccaa actactcggt agatggcgag ataacgcggc actttaagcc aaatgatctt
    10501 atctgcttct ttaatccttt cctctaatgt agaagtataa tttccttcaa caatccatga
    10561 cggattagat accataaacg attgctgttc ttgcaaaaac cacttttttg cctgaatact
    10621 gtagtctgtt gtatgccata aaaggtctag cggcagtagc ggaaagtcgg tgatttcttt
    10681 gatcttcctt gcgagggtcg attttcccga cccactttgt ccaatcacga tgatcttcat
    10741 tcttctccct cacttctctt tggaatttgg ttcgatcata ccacttataa cgccgcaaaa
    10801 aaacaaggga ctgtgacaaa agtcgtgtca aagtcccttg tttcgaataa atggtgttca
    10861 atcagctgac cttcagcatt aactcaaaaa acggcaaaat atgaggagct attttttcgt
    10921 ttgttcctct aatactcagg tcaaatcgct gattttacaa cctcttcctt aaacggtgtt
    10981 ctcctgccaa cacctcggtc acaaggcaca atagtcaaca aacatgagaa gttgtttttt
    11041 gaaattgctc cttgtgactc ggagttaaac ggcaggctca ctacctcttt cttaaacggt
    11101 gttcaaaagc ttgcatctgc ggtaataagc ccagcaaaac gaaaaatatg aggggctatt
    11161 tttgtttggc tgttcttatt acttgatgca ggacagcttt ttcacaacct ctgattcacg
    11221 gtgttccaga agtagcttct gcgaaaaaca agccgaaact tcacaaaaat ttgagaagca
    11281 attttcgtaa attccttctt atttcttgaa gctgaccact tctgtcacaa cctcttgtaa
    11341 caagtatttc tattttaagg ctgaaccact gtttctggtt cagtgatttc tttgtttttg
    11401 tctcgacgag caattgctgg caagatcata cctaataaga tcaagacaat tggtgtgatg
    11461 atattcgtga ataattggaa ccaccatgct ttaggatcag cagtataatc tacttttggc
    11521 accattccta ggatacatgc aaacgcagtg aaggcaaagc accaagcacc aaagataaaa
    11581 ccgatttttg gatttttaac aaatttatat tcagaattga atttcttata agctttattc
    11641 aacatcatat atgccaagaa cacccatagg taacgcattg gcatgacaac tgagttcaag
    11701 ttcgtcaacc attttactaa ttcattcata tctttgatac caaagatcgg caacaaaata
    11761 atgattccta ctagtatacc tgtcagaaga taaccattca ccaatgtacc tttacgatta
    11821 cgtttacgta gccagtttgg tacaaattct ggatccgcat ctgctaacaa gatttttagt
    11881 ggtgcatcaa ttgaaaaggc taatgcggag atttgtccaa tcatgtttgt caatgcgtaa
    11941 atgatcatca atgagttacc gataccatag taattaccta aaatttgaaa agcactgtat
    12001 gccccatttg ccatcaagtc tttaggaata ttatcgctag caaacagcat acccattgcg
    12061 actgagccta atacagcaca aatccctacc attgctgcta agaagatcat ccctttagga
    12121 aattcctttg caggatttct tgtagagttg acataagggg atattttttc cgctcctcca
    12181 actgcaaata ctagcatcga aacggttgtg aaataactga aatcaaatgt tggaatatat
    12241 gttttcactt gattcatatg tggtgtggca aattccatcg ttggattgat gaacggtgcc
    12301 gttacagcta aaagaataaa taagatcgac atgacgaaca tcgctgttcc ggccagtccg
    12361 ccaatcactt tcaaagtaga aagtcctttt gttgataaat ataaaaaggc aagaaatata
    12421 ataagtgaaa taactgctac catttgtact gacatcgtat ttacgatatt tccatttcct
    12481 tggactgccc aaccgccagc aatcaggatt gcttgaggct tttgtgccaa ataaggaata
    12541 tggacgaccc agtaagtcca agcggcatag tatgccagtc gtttattaga tgtcgtattt
    12601 tcgacccatg aactgacgcc tcctttacta tccttgaagg ctgaccctaa ttgtccaacg
    12661 atcaatgcgt atggaataaa ataaatggcc aaaatcaata gccaagaggt gacaactgat
    12721 actccttgct gagcatagtt attaactaca ttccccatgc cccaaaccat gttaaatgca
    12781 attaacgcaa cagtaaacca gcgtaattgt ttgttgttca ttcgttctct cctttatgat
    12841 aaaaatttgt tatccagatg taatcatatt caatttttaa caaacttaca agacagtgtt
    12901 attttatgtg tgtattcttt tatttaatac acatcgtttt ttcatatttt ttccatcaaa
    12961 aaaataagtt attttctttt atttcattta ccttattgaa tttcaagcta ttttgaattt
    13021 tctgcaaaat taaaaacatt agttatttta taatcctatc tattttcttt acatttttca
    13081 ttaagaaaag gatataaaaa aaagaggacg ttcattcgtc ctcttcattg atcaacgttt
    13141 attttttaca tgcaagcttc gcatggcatt caaaacagct aatactgtca ccccaacatc
    13201 tgcaaatact gcatctccca ttgatgcaaa accaaaagca cctaaggcaa gtaccaaaat
    13261 ttttatccca atagcaaaga caatgttctg tttgacgatt ttcaatgttt tctttgctaa
    13321 atggattgct tctgcaatct tcgatggttg atcattcatg atgactacat ctgctgcttc
    13381 aattgcagca tcgcttccca atccacccat tgcgattcct acatctgctc ttgctagcac
    13441 cggtgcatcg ttgattccat ctccgacaaa tgcggtcttt ttattgtttc tttgtaagat
    13501 ttcctctaac cgctgcactt tatcttctgg aagcaattcg ctatatatct tgtccacgcc
    13561 tacttgcttc ccgatatgat cagcaatttt tttcgaatcg cccgtcaaca tgactgtgtt
    13621 cttcacacca gcctttttta attgaaccaa tgcgtctacg gcatcttctt tcaaggtatc
    13681 tgcaataaca agataaccac tgtaactttg atcgatcgct agataaagca atgtaccgat
    13741 ttcttgactt gaaggaaaag agatttcaaa tctttccatc aatttgtgat tacctgctaa
    13801 tacttgtttg ccatcaactt cagctaagat cccttcacct gcaaattctt ggatattagc
    13861 tgttggtaaa agcggacctg cgtagccttc taaaacagat tgagcaatcg gatgtgtaga
    13921 aaactgttct gcactcgcaa catattgcat gaatatcttt ggatcgattt ttgtatcgat
    13981 cgtctggatc gaaaagtcac ctttcgttaa tgtgccggtt ttatcgaata ccactgtctc
    14041 agtttgtgca agcaactcca agtaatttga accttttact aatacaccga ttttacttgc
    14101 tcctccgata ccgccaaaga aactaagggg tacggagatc actaatgcac atggacatga
    14161 gatcactaaa aatgtcaatg ctcgatagat ccattcagaa aacgccgctc cagaaacaac
    14221 aagtggaggt aaaacagcta ataaaacggc caatcctaca acgactggtg tgtaatagcg
    14281 cgcgaattta gtaatgaaat tttcagctgg tgctttttta ctgctggcat tttctactaa
    14341 ttctaataat ttgctgatag tagaattttc ataagatttt tctacttgaa ctaaaaatgg
    14401 tttattttta ttgataaatc cacttaatac tgtttcacca acatatacag atttagggac
    14461 tgattctcct gtaagtgctg acgtatcgac taatgattct ccttcgatga tcgttccatc
    14521 taacggtaca cgttcaccag gcttcacaag tacaaactga ccgatctgca cgtcttcagg
    14581 gttcacggtc atcaatcctt ccgtcgtctg cacgtgagct gtttctggac ggatcgccat
    14641 caattcgcga atcgattttc ttgaatgact gactgccaat ccttggaaat actcgccgat
    14701 ttgataaaat agcatcactg ctacggcttc tggatattca ccgatcaaca tagcgccaat
    14761 cgtagcaaca gacataagaa aattctcatc aaagattttt cctttgacga tattcatcac
    14821 tgccttcttc actacatcat atcctatcag cagataaatc aataaatacc ctatcaagcg
    14881 aattggttca ttaaaatcaa ataatagcaa taaagcgata cctgcaaggg aaaataaaat
    14941 ccggaacagc gtatttctct ctttttcatt tccatgttca gatacttttt ccttatctat
    15001 ttctgttact ttgacatctg gttctaattc cttcactact ttttttattt cttgttcaat
    15061 cgtagccaaa tgatcttcct ctgcgtcaat cgttagtttt ccagaagtga agtttaccgt
    15121 tgcttccttg actccattga tcttctgaac tcctttttcg attttcattg cacagttcgc
    15181 acaatctaaa ccttctaatc tgtaactttt cattttaatg acctcctcgc ctcaacatat
    15241 gaatatctct tcataactaa ttataaatga acggttattc atatgtcaag gtatccgaaa
    15301 gaaaaaatga aaaacatctg catcggaaaa tttcttccat acagatgttt tggcttattc
    15361 tttctttttc ttttcgatca ttgccactgc tcttatccaa cccgcacttg ccttcttgat
    15421 cttgacagga tagcaactaa gtttgaagcc tgttgctggc aatttgtcta aattcattaa
    15481 tttttcgata ggacaatatc ttttttcaat ccctgcaaaa tgtccttccc agatattcga
    15541 agctccacta cgctttcaaa aatatagaaa gagttcttta atgaaaatta tttcaacttt
    15601 ccataaacag taaccccata taaataaaag acgtaaaagt cacatggaag aacttataca
    15661 ggagaacgca tagagtcagg tgaaatacat gtatcccacc tgactctatg ctttatctaa
    15721 cctttattat tctcttttat acaatttctg caccgaatgg catcaacgcc aatcgagcaa
    15781 gtttgaaaga ttgcttggca aaaggtatcc ctatgatcgt gatacataga aggatgccgc
    15841 tgacgacatg tgcgagagca attggtaggc ctgaaacgat cagccagatg atattaacaa
    15901 tcaatgacat gccagactgg tgataaatta cttctttgcc aaaaggcgca aaagaaaggg
    15961 aggcgatctt aaaacattgc ataccgattg ggatacctat gatcgtgata caccaaagta
    16021 tccccgctgc taaccagcta agaccaccga ttagtccgcc gaatataaac cagatgacat
    16081 ttcctaaaca actcattgta tttctccttc tattactgtt tttgattaaa actgggcaaa
    16141 aaatgatttt attcttcttt ttttagcttc cagtatcaaa tattctgcaa attttttttg
    16201 gatttcttcc gtattttctt ttgttactaa tgtgtgttgg attagttttc ctgatggtcg
    16261 ctgatccaat cgttcttctg actgttgcac gtccgcttgc gcaaatccga taatccgttt
    16321 ttcttttgtt acagcaacga gcaatagttt attcttatca tttaggtcag ctgccgtttt
    16381 tgcttttacg aatgattctg gatgatcagt aatcagctga ttgatttgag gtagatcttc
    16441 ttttactgcc caccgtattt ccatcatttc tcacttttct ttcgctcatt tttatctcca
    16501 ctaaaaaaat cgactgcggc aattgcatct atccagcttt gtgcaatgat ctcatgtccg
    16561 ccaatcgttg ggtggacccc atcttctctt gtatatttcg aaaaaccata aacaatccct
    16621 aaagcattga atataccatc taaaggaacc agcaatgcgc catattcctt agcaagttta
    16681 cgaacaattt ggattttagg gtctaagtct ttacgccagc catgacggtc gtcggttata
    16741 ggaagtacaa acggctccat caagatgatg ttgcagattc ccactgtttg aagttcattt
    16801 agtaattttc gataaacgga ttcaaattgc tgagcagatt tctcagttcc gaatatagcc
    16861 tgatcgctag tattatgcca ggtatcattg attccgatca aaatcgatac atagtcaggt
    16921 tgtaaagcta aacaatcttc ttgccagcgt acttgcagat ctgcaatttt gtctcctcct
    16981 atcccacggt tcatgcattc aaattccatc gttggatatt gggagattag ttttccggca
    17041 atcaaaagtg gataaccttt acctagatca gttgcttctg ctcggtctct tcctgcgtct
    17101 gtaatgctat caccgataaa taatatacgt tttttcattt gtcaaaaact cctttttgaa
    17161 taaaacgatg attttcttcc ttatattatc ccataagccc tatcaagacg aaagagaaaa
    17221 tatatgtata aaaaatgaca ccagcctagt cccttcaaac aattgaatga acgctcatca
    17281 agtgtctagt tttttatgct atttttttct taacgtgccg gattcccctt gattccttcg
    17341 ttgtttggtc cagagagatc gatcacacct aagcttccgt caatcagacc actgatgacg
    17401 ccatcagaac atatatttat aggctcatct aagacttcta gtaaatgtcc ctttactaat
    17461 atctcttcta gattgcttgg gatagattgg tcataacttt atctggtccg atgatttcaa
    17521 gggtgaattg aacttacata tggattattg catgctgaaa atacggacct actccatctt
    17581 cgaatgttac tattagtttg ttttcaggtg ctagatgctg ctttatttca acagcagaag
    17641 catcatcaaa tcagatttcc atttgaatta ccttctttgt aaatgtttga ttgattgcga
    17701 tttcgttata gaaccttgtg aatcaaatag caatttcttt tgctttcttc tcttgtctgc
    17761 tggaaacttc ctttatcccg tattttaaaa aaagaactgc gagagttcgc agttcttttt
    17821 tagaataaac ggtgctctcc ggccaactcc tcggtcacaa gtcacaatag tcatcaaaca
    17881 tgaaaaactg ttttttgaaa ttactccttg tgactcggag ctgaacggca ggcgcacaac
    17941 ctcttcctta aacggtgttc aaaagccagt ttctcggtat taagccaaat ttatgcaaaa
    18001 atgtggaaag ccatttccac aaaatttttc ttaatactcg aaactaaaca gctttttcac
    18061 aacctctcca ctaaacggta ttcaaaagct tacatctgcg gtaataagtc ccgccaattc
    18121 aaaaacatga acagctgttt ttgcttggct gttctaatta cttgatgcag aacagctttt
    18181 tcatcacctc ttatggataa attcggttca acaaacgtgg gaatggaata gcttcacgta
    18241 catggtcgat accagcaatc caagtgactg ttcgttcaag acctagacca aaaccagagt
    18301 gcggaacaga accgtattta cgtagatcaa gataccatga atattctttt tcatccaaac
    18361 cgtgattacg gatttgttct agcaagaaat catagtctgt tgcccgttcg cttccgccaa
    18421 taatttcacc gtaaccttct ggtgcgatca tatctgcaca gatcaccacg tcttctcttg
    18481 ttggatgtgg tttcatgtag aatggcttga tggcttttgg atagtttagg ataaagacag
    18541 gctgttcgaa tgaattcgca atgaacgttt catgaggtga accaaagtct tcgccccatt
    18601 cgatgtcatc aaatccattt ttcttcagta attcgatcgc atcatcataa gtaatacgag
    18661 ggaatggcaa ttttgtataa gtttttaaga cttctttgtc tcgtcctagt acatctaatg
    18721 catattcgca atgatctaaa acattttgta ctaagaatgc tacatattgt tcctgtactt
    18781 ctaaactttc ttcttgatga gtgaaagcca tttctggttc gatcatccag aattcgatca
    18841 aatgacgtcg tgtttttgat ttttcagcac ggaaagtcgg accgaatgaa aagacttttc
    18901 cgaaagccat agcagcagct tccatgtata attggccact ttgagataaa taagcttttt
    18961 gatcaaagta atttgtttcg aatagatccg tagtgccttc tggtgcagaa ccagtcaaga
    19021 tcggcggatc aattttgaca aaatgatgtt gattaaagaa ttcatacgtt gcacgaatga
    19081 tttcatttct gatctgcata atcgcatgtt gtcttgaaga acgcagccat aaatgacgat
    19141 gatccatcaa gaagtctgtt ccgtgttctt ttggtgtgat cggataatcg tggctctcgc
    19201 ttaccacttc cacatttgta attccgattt cataaccaaa ttttgaacga ctgtcttcac
    19261 ggatttctcc agttactaac acggatgttt cttggtgtag atttttagct gtttggaaaa
    19321 cttcttccga cacttcgctt tttacaacta caccttggaa aaaggctgtt ccgtctctta
    19381 attgtaaaaa tgcgattttt ccgcttgatc gcttatttgc gacccaagcg ccgattgtta
    19441 ctgtttctcc cacatggttt ttcgaatcga tgatttgaat ttgttccacg tatgactctc
    19501 cttttatatt ccttgaattt ctttaggatt aattttgact tttactctca ataaattgct
    19561 tgattctgcg taccgcttct tctaacgtag cgcgatcagt agcataactc atgcggacat
    19621 tttctggtgc cccaaagcct tcgccagtca caagcgctac ccctgtttct tctaaaagat
    19681 cttctaccca ttgtgtgaca ttttcatatt tacacatgcg tagcgtttct tttacattag
    19741 gaaaaagata aaaagctcct tgtggctttt caagagaaac acccggcagt tctgccacaa
    19801 gcgaatataa cgtattcagg cgttcttcaa aggcgttccg catttcttcc actgtatctt
    19861 gctcgccttt caatgcttca acagctgcat attgactgac tgctgtcgga ttactggttg
    19921 actgggaagc aacagcgatc attccattga tgatcacagg atttcccacc gcataaccaa
    19981 tgcgccagcc tgtcatcgca tatgttttag acacgccgtt gatgatgata gtctgatttt
    20041 tgattgcttc tgaaatcgtt gcaattggag taaactcatt gccattataa actaaacgac
    20101 cataaatatc atcagcaact atcaaaatat cattttttac tgcccattca ccgattgcct
    20161 gcagttcatt cttgctataa atcattccag tcggattcga tggagaattg atgattacgg
    20221 cttttgtttt ttctgaacgt gcttgttcta gctgttcaac agtaactttc cagctattgg
    20281 attcttcccc tttcacaaag acaggaagtc cttctgccag ttttacttgc tcaccgtaac
    20341 tgacccagta aggcacagga atgatgactt catcttgcgg gtcaaggatc gtttggaaaa
    20401 gggtatacaa agcaaatttc gctccgtctg ttacgactgt ttgtgaaggt tcatagacaa
    20461 gtccatagtt tttcttcaga taatcaacga ttgcctgtcg aagctctggg attcctgctg
    20521 ttggtgtata atagctagct ttcccgttgc ggattgcttc gattgctgct tcttggatgt
    20581 tttctggtgt cgcaaaatcc ggttctccca cagtcaaact cagcacatct ctgccttttg
    20641 cttttaatgc cttggccttt gccgcagctg ccaaagtgac agacggttct aatcgttttg
    20701 ttctttttga taactccatc ccattcattc ctttaccttt taaattccct tgattgtctt
    20761 gacttcatct ccagattcaa agccaatcag gtaataattc agtttcccat ttgtttcttt
    20821 tcctactact tcccacacag gctgatcatc atacatccct aaagcagctt tttcgatttg
    20881 gatttcagga tgggccgcag caattgtctg ttttgcttcg ttttcagtca gtccctttgt
    20941 ttgatccaat acttttactt tttcaccaga tttaggaatg ataacggcga tttcttttcc
    21001 tttatcattt gtacctgtca gtgaaaagta tgtcttcttt cgagtaaacc aataaaaatg
    21061 atcggcttcc tcaagatttg catatttctt tgcgatttct actgcttctt tcttcgcctg
    21121 caccgccgga cgactggaac gcaagtaaaa aatcgagctg atcacgatga ccgctaataa
    21181 aaatacgatc aagccaagta acacgcgatt aatcgttttt tcctttgtct gttttttctt
    21241 caagggtcgt cgctccttta tcttcattcc ttttcattat agcagatttt aattatgaaa
    21301 aaagacagct cctctaactt ccttcttcat ttttctttaa gaattcatgg atgtcctgat
    21361 agatttcctc catagctagc tctttgatcg gtactttttt cggtaatgca tggatgatcc
    21421 gtgcaccata ttttgcagtg actagtcttc gatccaaaat aagcaatacg ccacgatctg
    21481 tctccgtcct tatcaagcga cctaatgctt ggcgtaactt caaagctgct ttaggtacgg
    21541 attcctggta aaaaggattg atcccctctg attctaaata agcgttccta gctttgacca
    21601 tcgggcgaag cggattatcg aagggtaaac gtgtgactac aacgatctgc aaagcatccc
    21661 caggcaaatc tacaccttcc caaaagctgt cagcgccaaa caatacgctt ttttctgaca
    21721 aaatgaagcg tttcaaaagc ttctcccggc ttccgccaaa cccttgagct agtatttctc
    21781 gtcctttttc tagcatagac agatgcattt tctgatagac cttctgcaaa acatcatgag
    21841 aagtgaataa cacaagtatt ggccgatctt cttgttcgat cagacctgta agtgctgtct
    21901 ctaaataatc gatatatgct tgattgctga cttgatggac ggcaggtgcc tcttttggca
    21961 catagatcct tgcctgtttc tcataatcat aaggagaggc aatcacttta agaggtgctg
    22021 cttcaatgcc aagccgctta gagagatagt gtcgattagg gccgatcttc agcgttcctc
    22081 caatataaag aatacgatca tatcgaggat accaaacagt cgacggcaac atagccgctt
    22141 gaaaatcatg gagatgaaaa atcatctgct gcgctgtgtt cccaggaacg aaccaatgga
    22201 tcaaatgatc tcgccagtct tccagccatt gatccatcag caagtactgc ttgtctaatt
    22261 gatcaaataa gctatataaa cttgctaaat cgatccgcat ctggtttgtc cagctttctt
    22321 ggataatctc aaaagtcaga cgcatttgtg actgtagctg ctggatctcc tgataaaaaa
    22381 gctgcaggtg atcaatggct gtcccagatt ccagtggcag ctgatccaac atctcttttg
    22441 tcatcatgac ttcttctgga tactgtccgt taggttgctt gccgctcact aaactcatta
    22501 atccttctgc catacaaatc tgtgcttcgc atagcgcaga aagttcttct cgataaatcg
    22561 ataaccagcg taaggcttca tgttctttcg gtaaatagct ttgtattcgg tcaaacagct
    22621 gatttggttc ttctaattgc tggatttgtt tatggaaata gttaatactt aatcgtttgt
    22681 catttacttt ttcagcgatt tccggcaaat gatgtacttc atcgatcaac aaaaatggac
    22741 tagctggaag caatggttct tttcgctgtg tttcttgtat taaaaacgca tgattgacaa
    22801 tcaaaaaatt actttgcctg attttctttt gcaagaaacg aacaaagtct tgttcgtaaa
    22861 atgactgatt tcttgctaaa aatccaatac ctctgtgcgc gatatctgca aagaatgaat
    22921 ggttcaaatt tgttaaatgt aattcatcca aatcaccggt cttcgtttgc gtcagccaaa
    22981 ctaagaccgc catttgatac aaagcatatt gtttttgttc tggcggttcc acaagtgtgc
    23041 ctttaaaacg ctgtaaatca atatagtggc gatagctttt gataattaca ggttgtatgg
    23101 gctgatctag caattgattc agcaatggaa tgtctttttc tatgatctgc tgctgcaaaa
    23161 ctagcgaaac ggtactgatg acagcgggtt tttcaggtgt agccaaataa ctcaatggca
    23221 gcagataacc gattgtttta cccattcctg tagctgcttc gatcatcaaa tcttttgatt
    23281 catcttttgt gaaatggtcg tagaccgcat tcatcagtct gttctgttct tttcgataca
    23341 tcagtgtttt accaaacatt ttttcttttg cttgtttttt tcttggatat gtccgctcgc
    23401 cataatggac ggatgtgaat agttccactt cttttttctg caaagctagc ccatcgacga
    23461 tttctaatga gggatcaagt ggctctggtt tttctttcat ttcttcaatc acatgataaa
    23521 tgaaacgact cgtatccata cctgtgtgtc tacttaatcg cgcaatctgc tctaacgtga
    23581 tgattggcaa ttttctcatc cgttcttcga tcagcaaaag aagttgaccc gtcacttcgg
    23641 catcactatc tgcctgatga ggattctcat gaataaatcc aaggctttct gacaaatcag
    23701 ctaagcgaaa gcttggttcc gtcggcaaga aaatttgtgc aagttctact gtatcgatgc
    23761 ctggtatctt caaactagga agtccgcatc gcatgagttc atggttcaaa aaattataat
    23821 caaaataaat attatgcgcg acaaatatgg tgtctgccaa aagattgtaa atcgtttggg
    23881 cgacatcttc gaaataaggc gctttttgga cgcgttgatt cgtgatccct gttaaatgct
    23941 ggatttgttt tgaaatcttc cgccctggat gaatatcgat cgaaaaacgt gaagtgatcc
    24001 gacctgattc aatcatgacg cagccaaatt ggatgatccg atcttctttt ggattcgtcc
    24061 cagtcgtttc gatatcaacg actgcataag ttcttggttt caaaatatct tcctcttctc
    24121 ctgcctctaa tgttcttttg aaattatact acaaagtgca gaaaaatact ctcatcgctt
    24181 tttaaagaaa atagacaaaa acgcccagac acgcaaatgt ctgggcgttt attttttagt
    24241 ataggttaat taagctttag taacgtttgt tgcttgaggt ccgcgttggc cttcttcaac
    24301 atcgaaagtt actgcttggc cttcttctaa agttttgaat ccgtcgcctt ggatagctga
    24361 gaaatgaacg aatacatcgt ttccgttttc tgcagtgatg aatccaaatc ctttttctga
    24421 gttaaaccat tttactgtac ctgtttccat aataaaaatc ctccttgtgt atcaacacat
    24481 attttgcaat tacttgaatg gtgtatatct ggaagatgtt tatttgaaac aagctaccac
    24541 agattaccga acaaaaacta ctcctatagt atatcatacc gtttacaaaa aagctagagt
    24601 ttttcgactt tttttattaa aaaaagtttt ctcagcgatt acataaagtg aaaaaccgaa
    24661 ctttttttaa aataaacgac atattgttca gttggtgttt ttttgctctg atgttcttct
    24721 ttaaactaaa aaaattattc tttctgacta cttatcggtt ctgtttcaac ggtcgaggct
    24781 ggggaagatt ctttagtagg tctgatgttc tcatggtatt tctgatagcc tatgacagtt
    24841 accagaagaa caaggcaaac caatacgatc aacgagatta gtttttcttt tttgctcata
    24901 tctatacctc ataaataaca ggatgatgtc catcatattt ctgagtatga gtaaaagcaa
    24961 aagctgcagc tgtagaatgt aagaaatgcc agcaactttc ataatcacag gtcggacagt
    25021 accaaaagta accaaatctt ggctgcaaag accgttcttc tgtttcagga atcgcagaat
    25081 caagatctgt tgtctgtaca taaacatttt tgtacagacg tgtgcctgta ataggagacc
    25141 gctgtgtttc ttcagcaaaa actggctgac ttgttaaact tagggataga aacagcaaac
    25201 accataacag tctttttttc ataaagacct ccttatcgat aagtttttcc caattaaaat
    25261 catatctcaa gaacgcccgt tattcacatt ttgttcataa atgatgtttt ttgtatcata
    25321 atcgtcaaaa agaggtcgtg accacgtcac aa
//
LOCUS       DAXQKX010000036        24502 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.036, whole genome shotgun sequence.
ACCESSION   DAXQKX010000036 DAXQKX010000000
VERSION     DAXQKX010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24502
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.036"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(115..1695)
                     /locus_tag="ACF3MF_001680"
     CDS             complement(115..1695)
                     /locus_tag="ACF3MF_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HFE3927669.1"
                     /translation="MNNPELKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(2096..3472)
                     /locus_tag="ACF3MF_001681"
     CDS             complement(2096..3472)
                     /locus_tag="ACF3MF_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HFE3927670.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(3600..4688)
                     /locus_tag="ACF3MF_001682"
     CDS             complement(3600..4688)
                     /locus_tag="ACF3MF_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFE3927671.1"
                     /translation="MFWSLELLIIAALIMISSEINFIFEPIGTFFSTLFAPVLIAGFL
                     YYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQISSLASNMPDF
                     IKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSLGSIVGTIASA
                     TVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTLANYISGQAIE
                     CLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLVTVFNDPVKAL
                     LCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLGIFLGVPFYAI
                     CKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            4860..5140
                     /locus_tag="ACF3MF_001683"
                     /pseudo
     CDS             4860..5140
                     /locus_tag="ACF3MF_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(5218..5751)
                     /locus_tag="ACF3MF_001684"
     CDS             complement(5218..5751)
                     /locus_tag="ACF3MF_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HFE3927672.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(5845..7023)
                     /gene="mutY"
                     /locus_tag="ACF3MF_001685"
     CDS             complement(5845..7023)
                     /gene="mutY"
                     /locus_tag="ACF3MF_001685"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HFE3927673.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(7016..7813)
                     /gene="recX"
                     /locus_tag="ACF3MF_001686"
     CDS             complement(7016..7813)
                     /gene="recX"
                     /locus_tag="ACF3MF_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HFE3927674.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNRGKSQKELLRKIQQTLMTKGFSQEVIQQAMADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            7920..9302
                     /gene="rlmD"
                     /locus_tag="ACF3MF_001687"
     CDS             7920..9302
                     /gene="rlmD"
                     /locus_tag="ACF3MF_001687"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFE3927675.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMICEINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(9476..10054)
                     /locus_tag="ACF3MF_001688"
     CDS             complement(9476..10054)
                     /locus_tag="ACF3MF_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HFE3927676.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            10376..10846
                     /locus_tag="ACF3MF_001689"
     CDS             10376..10846
                     /locus_tag="ACF3MF_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TspO/MBR family protein"
                     /protein_id="HFE3927677.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGEYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(10954..12180)
                     /locus_tag="ACF3MF_001690"
     CDS             complement(10954..12180)
                     /locus_tag="ACF3MF_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFE3927678.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(12934..13134)
                     /locus_tag="ACF3MF_001691"
     CDS             complement(12934..13134)
                     /locus_tag="ACF3MF_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFE3927679.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(13268..13876)
                     /locus_tag="ACF3MF_001692"
     CDS             complement(13268..13876)
                     /locus_tag="ACF3MF_001692"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HFE3927680.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNAAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(13961..14431)
                     /locus_tag="ACF3MF_001693"
     CDS             complement(13961..14431)
                     /locus_tag="ACF3MF_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HFE3927681.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(14479..15393)
                     /locus_tag="ACF3MF_001694"
     CDS             complement(14479..15393)
                     /locus_tag="ACF3MF_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFE3927682.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKNVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            15539..16342
                     /locus_tag="ACF3MF_001695"
     CDS             15539..16342
                     /locus_tag="ACF3MF_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HFE3927683.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            16520..17467
                     /locus_tag="ACF3MF_001696"
     CDS             16520..17467
                     /locus_tag="ACF3MF_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HFE3927684.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(17535..17828)
                     /locus_tag="ACF3MF_001697"
     CDS             complement(17535..17828)
                     /locus_tag="ACF3MF_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HesB/YadR/YfhF family protein"
                     /protein_id="HFE3927685.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEMDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(17856..18521)
                     /locus_tag="ACF3MF_001698"
     CDS             complement(17856..18521)
                     /locus_tag="ACF3MF_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HFE3927686.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(18661..19293)
                     /locus_tag="ACF3MF_001699"
     CDS             complement(18661..19293)
                     /locus_tag="ACF3MF_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFE3927687.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     ALRPDVILMDLVMEEMDGIESTKAILKDWPKAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNDPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(19300..20367)
                     /gene="liaS"
                     /locus_tag="ACF3MF_001700"
     CDS             complement(19300..20367)
                     /gene="liaS"
                     /locus_tag="ACF3MF_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     LiaS"
                     /protein_id="HFE3927688.1"
                     /translation="MMGRISKAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLMAISLGVGLIVFLLLSLIQKAKYGKIEEKLRALSSGNYESKLLHQP
                     IPSASDDLYIKDIDMEITKIKEKMIEVSSELQIMTSRPQYVDGQTKEEILKLERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWEVEDVKLTSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVETKVPLMKEA"
     gene            complement(20364..21095)
                     /gene="liaF"
                     /locus_tag="ACF3MF_001701"
     CDS             complement(20364..21095)
                     /gene="liaF"
                     /locus_tag="ACF3MF_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HFE3927689.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKYPRTKFQNFQLILGSLVIFFSLVNSPALWMMVVLAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMVQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAIISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKICSS
                     DYDENPRRLKIITNTLVGDVEVIRI"
     gene            complement(21263..21742)
                     /gene="greA"
                     /locus_tag="ACF3MF_001702"
     CDS             complement(21263..21742)
                     /gene="greA"
                     /locus_tag="ACF3MF_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HFE3927690.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGD
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(21878..23053)
                     /gene="mltG"
                     /locus_tag="ACF3MF_001703"
     CDS             complement(21878..23053)
                     /gene="mltG"
                     /locus_tag="ACF3MF_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HFE3927691.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELYQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVQKYVNNS"
     gene            23218..24378
                     /locus_tag="ACF3MF_001704"
     CDS             23218..24378
                     /locus_tag="ACF3MF_001704"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFE3927692.1"
                     /translation="MSKGKHRKKQKISISFLVILLLSVSFFSTGIIIGGQLTKIPHSQ
                     TYKAEPTQLTSNLTPDEQRLASKIDQLLQKSDYIGSIYVRKNNRVLLEKGYGYANLRV
                     KESNSPSIYYQIGSIQKAMTALLILKQIQAGKLTFDTKLAEFYPQIPGSQQITIKNML
                     YMRSGLHRTASPDKPMSDSEIIQFALHHLKLTDYDTYHYEPLNYTLLTGILIKLTNQP
                     YETLLKKEIIRPLHLEHTDFYDNVKNSPQHAVSYQMSATDDYSKALIEPETDIRNELG
                     TGNISMSVYDLNKFFTSVLSGGIIPKELLFSLWQNNGDKHPYSGGVYSGNDYILAQGN
                     INRFHAVVAMKKDTKDAIVMESNIQSDKNIKLPATDLRNQIYELMEGVHLSN"
BASE COUNT         7356 a         4987 c         3954 g         8205 t
ORIGIN      
        1 tagtaaaaag agccgtcacg gaaaatccgt cacggctcta aacaaaatat gagagactgt
       61 ttttgtttgg ctattcttat tacttgatgc agggcagctt gtgtcaagac ttctttacat
      121 caaacttttt aattttacat taggatattt atccgcaaac cagcgttctg caaattggtt
      181 ctcgaataag aacaatggtt ggtcgaaacg gtcacgagcc aagatattgc gacttgaact
      241 catcttctca tccaaatctt ctggatcgat ccagcgagcg attttgtgtc ccattggaga
      301 catgattact tcggcgttat actcatttaa catacgatat tggaatactt cgaattgtag
      361 ctgaccaaca gctccaatga tatattcttc cgttagatat gttttataaa gctgaatcgc
      421 tccttcttga actaattgat agattccttt gtggaaggat ttttgtttca tgacattttt
      481 tgcagtcact ttcataaaca gctctggagt aaatgaaggg agttcttcat aagcaacttt
      541 tagttttcct tcgaacaatg tatccccaat ctgataattg cctgtatcat atacaccgat
      601 gatatcgcct gctactgctt tttcgacgtt ttctctcgaa tctgccataa attgtgtgac
      661 attgcttaat ttcagttttt tatttgtacg ttccaaccag acatccattc ctcgttcgaa
      721 tgttccagaa cagattcgga caaaagcgat tcggtcacga tgggctggat tcatatttgc
      781 ttggatcttg aatacgaaac ctgaaaattc ttcctcataa ggacttacca tctgatcatc
      841 ttgtgttttg tgtccataag gagctggtgc caattcaacg aaagtctcta aaaaagtctg
      901 tacaccgaag ttagtcaatg cagaaccaaa aaatactggt gtctgatcgc cacgagcaat
      961 tttttcttga ttaaatgcat ctccagcctc tttgattagt tctacttctt ctaagacttg
     1021 ttcatataag gaattttcag ttagaggatg attttcggga agcagtccat cttcatccaa
     1081 ttctactaat cgttcatcct gataattttc cggacgataa aactctacac gattatggta
     1141 gatatcataa agaccttcta gccctttacc cataccgatt ggccaattca tcggataaga
     1201 ttcgatatct aatagctctt ctaattcttc taacaattcc aatggttcac gaccatcacg
     1261 atctagtttg ttgataaaag taaatatcgg gatgccacgt ttttttacaa cttggaataa
     1321 tttctttgtc tgtgcttcga tcccttttgc actatcgatt accatgaccg cactatccac
     1381 ggccatcaaa gtacgataag tatcttcaga aaaatcttca tgtcctggtg tatccaagat
     1441 atttactcgt ttcccttgat aatcaaactg cataacagaa ctagtaacag aaatcccacg
     1501 ttgtttctcg atttccatcc agtctgattt ggcaaaatta cctgtttttt tgccttttac
     1561 ggtcccggct tgacggatag ccccaccaaa caatagtaat tgttctgtaa tcgttgtttt
     1621 cccagcatcc ggatgggaaa tgatcgcaaa agttctgcga ttgtccactt gttgctttaa
     1681 ttctggatta ttcataacct aactccattt cttccattca attatttata ttttctctag
     1741 gcacagattg tccgatctct taaagaaaga caatttcata tagggctgtg acaaaagccg
     1801 tgtagcagtc tctttttccg agtaaacggc gttctagaga cagcctatca gcaataagcc
     1861 cacccaagcc aaaaatacga aaagctgttt ttgcttggct gctcttatta cttaatgcag
     1921 gatagctttt tcacaacctt tgtcaactac tacaactgaa tcagtatagc atggattcat
     1981 cgaatgaaaa agccaccaaa ccataagagt caaatatttt tttgtcagct gactaaaaga
     2041 aaagacgtgt tgcttgttta ttcaagcaac acgtctttca taaccaagtt tccaattatc
     2101 ttcttggctc gtcatcttcg aattcttttc tgaagtatct tcgttcttct tcaggttccg
     2161 cttctgtttc ttccggatca tgaaaaatga cacggatttt aaggattcga gaaccttcca
     2221 tttcttcaga aaccagcgta atattatcga catcaaacga taacttttcg ccttcatccg
     2281 gaatcatgcc taatgctgta atcaaataac cagccatcgt atctacatca ctcatatgca
     2341 gatcactgtc aaaagcttca ttgaactcat caatcagcat acgtccttgg atgatatatt
     2401 cgtgttcatc gattttttca taaagattct caacttcatc tgattcatca tcgatttctc
     2461 cgacgatttc ttctaaaagg tcttctagtg ttgctaaccc aacgacgccg ccatattcat
     2521 ctaataaaat agccatctga ttctgcgtct ttttcatttc atataacaga tcatcaataa
     2581 agaccgtttc aggaacgaat aaaggctcct gcatgatttt cttgatatct aaattatcaa
     2641 aaccgaattt atgggcagct tttagtaaat tctttgtatg aaggattccg actactttat
     2701 ctttgtcttc gttataaaca gggattcttg aatagttttc ggataaaact tcattcacat
     2761 tttcttccac agtgtcgttg atatcaatca taaatgcatc cgttcgtggg accatgactt
     2821 ctcgggcaac tttcgtatca agagaaaaaa ccccttggag catttctaat tcttcattat
     2881 tcaatacgcc ttcgttttca agcatataac gcatttcatc tctggtcatt tttgaatctt
     2941 catcatcaaa agtcatcggc gtgatacgcg ccaataaact tgtggaagca gaaagcagcc
     3001 agacgaaggg cttagctact acaccaatca agcgtatcag ccctgaagtg aactttgcga
     3061 cttcttctga tttatttaaa gcaatacgtt tagggtacaa ttctccaaaa acaatcgata
     3121 cataggtcaa aatagccagc acaatgatat ttgcaatatt ttttgccgct gtgccgccac
     3181 ctaataccgg agctaaccgt tccgataaag tattagctag tgaagcacca gacaaaatgt
     3241 tgaccaaagt gattcctact tggattgtcg ataggaaatt atttggattc tgcaatattt
     3301 ttaaaagctt ttgagatttc acatctcctt catcagcttt ttgctcgatt cgattcttat
     3361 tgatcgaaac aacagcaatt tcggaagctg ctaaaaaagc attgatcaat gtcaaaacga
     3421 tcaataataa aatctgcgct aacagcgact gactctcagg gtcagcattc ataatcgcat
     3481 tctctcctta taaaattaat ttttagttta cgatagaaaa aaacgtggca ctatagccac
     3541 gttaaaatgg tatcacaaag caattttctt tgcaataaaa acaagtgtac taaaactacc
     3601 tacgaggtcg tagcaatttt cttcttgttt tcattttgct tgtcttcttt gacgattttg
     3661 attatatagg aaatgatcgt cttgcagatt gcgtaaaaag gaacacctaa gaagatacca
     3721 agcaatccgg caatatttcc agctactaga agaacgataa tgatcgttaa tggatggatt
     3781 ttcagtgatt tcccaattac attaggataa atgatattcc catccaactg ttggacgatt
     3841 agcacaacca cacaacaaag taatgctttt accggatcat tgaagactgt tactagaaat
     3901 gcaggtgcta gtcctagata aggtcctaaa tatggaatta ggtttgtcaa tcccgcaatg
     3961 accccaaata agaaagcata atccacacca attaccatat atcctaaaaa tgtgaaggta
     4021 ccaacgaata aacattcgat tgcttgtccg ctaatgtaat tagccaatgt tttattcagt
     4081 tgccccaata actccacaat ttggtttctt cttttttctg ggaaaaactg ttggatgttt
     4141 ggcactagtt tttctccgtc tttcaacata tagaacaaga tgaatggtgc tgtaatgatt
     4201 actacggttg ccgaagcgat cgttccaacg atcgaaccta aactattgga tactccacta
     4261 aggaattgct gaatgattgt cccgtaagaa atgtctaatt gctcaaaata tttattgata
     4321 tctacttcct tgaacaaagg caattcggct acctctttta accagctttc tacctgtttg
     4381 atgaaatcag gcatattaga tgccaatgag gaaatttgct gtactagact tgggatgaca
     4441 ctaagtaaaa tccaaataat tgctgcaact aaaaggagca gcacaattgc gacagcccat
     4501 attcttttga tttttgcttt catcaacagc ttgacaatag gattcaataa atagtaaaga
     4561 aagcctgcaa tcagtacagg tgcaaataac gtggaaaaaa atgtcccgat cggttcgaaa
     4621 ataaagttta tttctgatga aatcatgatc aatgcagcta tgatcaataa ttcaagcgac
     4681 caaaacatta gtttagactg tctaagtttt tcaaacaata gatttcctcc tttctttctt
     4741 actagtatat attatattcg ttaaaaattc ttttattctt tttttatttt tgaaaacttg
     4801 ccatactttt tatttgtttt attttccagt atactatacg aaaggaaggt ggctagacca
     4861 tgaaagttgt acaaacaaaa gatacaatga gcaatattta cttagatgct gtacggatca
     4921 ggcatcaagt ttttgtagtc gaacagggta tgcctttgtc tcgagaaata gacaaagatg
     4981 aagcccattg tatccacttc gtcctgtact cagataaaaa agaaccgcaa ggaactgtac
     5041 gtcttttgcc tttagaaaac ggaaaaatga aattacagcg gatggcgatc cttttgaaga
     5101 tgctggcatg cctcatattt atatgaaaaa gactttataa aaatttattt cgaaaaaagc
     5161 aaaaaacagc aagcttttga gaaaaatctc tcactggctt actgttcttt tttgtgttta
     5221 cttacgcgac aattgcttgt aacggttata ccaaatatca atatagcctt ccgagaacgg
     5281 gccatctcca ttattgatcc agtcaaccag aatcttcaca ttttctttta ggatgaagtc
     5341 aatatcgttc ggataattca tcattttgct gtgcatctca tattcatcga catccaatag
     5401 tcgtttctcg ccgtcaggaa ataccttgat atccaagtca tagtcgatat atttcaaggc
     5461 ctcatcgtcc agcaaaaaag gtgaagctag attacaataa taggaaaccc ccttttctct
     5521 gatcattgct attacattga accagtattt tttatgaaaa taaacaatcg ctggttcgcg
     5581 cgttacccat cggcgtccat cagattcagt gactaatgtg tgatcattca cgccgatcat
     5641 agagtgttcg cttgttttta ataccatggt atctcgccac gttcgatgca atttgccgtc
     5701 gtgcttgtaa ctttggatcg tcacaaactc tccttctttt ggaactccca tagcaaccct
     5761 tccttaagca gcattttgtg ctttgtgttt gggtgttcat tacaccgaca tcataattat
     5821 tatatcaata aaaatgagct ttgcctagaa aggattccta ttgtttcgat ttttctctaa
     5881 ctgatctacc agtttcattt ggaccttagg aaaaacgacc gaatcaaatg catcaggctt
     5941 caaccacttc gaagttttgt tctcggtaaa ttcttgttct gctccctcgg ttgcccgtcc
     6001 gtaaaaaagg agaacatgcc atttcagatg actaaaaata tgagtaactt ctcctaaatg
     6061 tcgtgtctgc caaacaaaga gttcctgctt ttcaaatggg agattttgct cttcttctgc
     6121 tactaggtca tcaaacagat cgatttctgg ctttgtttcc cattcttttt tcaatcgctc
     6181 atactcctct tgtgtcactt ccatcattgg aaatgtccac atattcgcca gcaatttttg
     6241 gctatctctt tcttcaaaat aatacgctcc agaatgattt tgaagagccg cactgatata
     6301 ataaacgtct tttggctttg ctttttttgt ttttacagga aaactcgttt ggattcctcg
     6361 tttgttagct aaacaaaagg cttggatcgg acaagtctca cactttggag aagttggtgt
     6421 acagatagct gaacctagat ccatcattgc ttggttgaat tcacctggat gcttttcatc
     6481 aatgattttc cgcatcgctt catcaaagat tttcctgcta gaagcttttg cgatgtctgc
     6541 ttcaatgcaa aacaatctgc tgactactcg catcacgttg ccgtcaaccg cgggttctgg
     6601 aagtccaaat gcgatacttg caatcgcgcc tgtcgtatat ggtcctattc ccttcaatga
     6661 gctaatttct tcaggcgttt gcggcatttc cccatcaaat tctgacatga tctgtttagc
     6721 agcagcttgg atgttccggg ctcttgagta ataaccaagg ccctcccatg cttttaaaag
     6781 cttttcttct ggagcatttg ctagctcttc aattgtagga aaccattcca tgaaacgata
     6841 aaaataatcg atcactgtgt ctactctggt ttgctgaagc atgatctcag agatccagat
     6901 acgataagga tcacgattat agcgccaagg caggtttctt ttttcttgtt cataccattg
     6961 aatgaactga tcttgaaatt cttttgtttc tttatctgtc catttttccc attctttatt
     7021 cactttcctc ttccttttcc gtaatgaatc gctggatcat atccaaatca aatccttttt
     7081 gatataagct ttgctttact tttagatttc tttttttagg ttcaaacctt aaatttcttc
     7141 gccatagttt atctccttgt ttgactaaat aatcatattc tatttcttga tctgcttctt
     7201 gcggaagatc agccatcgct tgttggatca cttcttgaga aaaacctttc gtcatcaatg
     7261 tttgttggat ttttctcaat aattcttttt ggctttttcc gcgatttttt ccaaacgctt
     7321 tttcggctgt ctgatgtgca ttttgaactt ggtcttcaaa tgtatattgg ctgagcgctt
     7381 gttcaatgat ttcaggtttc aaaccttttt gctgcatctg ctgcgctaat ttctttggtc
     7441 ctttgtcact taagcgcata ttcgtgcgca cataactttc cccatagacc aaatcatcga
     7501 caaggtccaa ttcttttaag cgggctacga ttttatttcg atcttcttga aggatttcct
     7561 tttcttttaa gtatgttcgg atttcttttt ccgatcgcaa ctgataactt aagtaattca
     7621 ttgctaggtg aaaaccgaaa tcagctccgc tactcttctt gatctcttgg atagtttctt
     7681 cgtctaattc ccgtcctttt aataatcgat agcgtactaa tacatcttca gatacttgta
     7741 aagcttctcc ttcagataaa tctacgcgat agaaagggcc tttgccttta ctgattctcg
     7801 taacggttaa cataaacatc ctcctcgaac atatattctc tatcatacca cagaaaatcc
     7861 ccgtaatcag gtattatatg ttagaataaa ccacagaaaa aagaaaaagg gagatactta
     7921 tggcagaaac aattgtcaaa actggacaaa cggttccttt gaaaatcaag cgtttaggca
     7981 taaatggtga aggaatcggt tatttcaaac ggttgatcat atttgttcca tatgcactac
     8041 caaaagaaga agtactagtg aaaatcacga aagcaactcc tcgctatgca gaaggagaat
     8101 taataaaagt caaaaaaaca agcaaagatc gcgtagtggc accatgtcct gtttactatg
     8161 aatgcggtgg ctgtcaatta caacacttag cttatcaagc tcaattggat tttaaaaagg
     8221 atctgctttt gcaagcattg gaaaaattca aaccagcagg ctttcgatct tatcaacttt
     8281 tgccgacgat cgggatggat gagccttggc attatagaaa caaagcacaa tttcagttac
     8341 gaaaaaataa gcagactcaa aaaattgaag ctggtttata cgaagcaaac tctcatcagt
     8401 tagtccctat aacagactgc ttggttcaag aacctcgaac acaaaaagta atgaatactg
     8461 ttgttcaact attgaataaa tttgatgcac ccatctatga tgaacggaca aacagtggaa
     8521 tcttccgcac aatcatggtt agaatcggtg ttaaaactgg ggagttacaa gttgttttta
     8581 ttactcgcag taaaaaattc ccgcaaaaaa acgcaatgat ctgtgagatc aatgaacgac
     8641 tgcccgaagt tgtttcaatc atgcaaaatg tccaggcaca aaaaacgtct ctcgtgatgg
     8701 gggatgaaac gatccactta tggggaaaag aagccattga agaacaaatc aatgaagtga
     8761 ctttcgatct ttctcctcgt gccttctttc aactcaatcc tcagcagacc gaattgcttt
     8821 atggcgaagg aatcaaagca ttagatgtcc agcctaatga aacgatcgtg gatgcttatt
     8881 gcggagttgg gacgatcggc ttaagtgtag caaaacaagc caaagaagta cggggaatgg
     8941 ataccgttcc tcaagcaatc gctgatgcaa aaaaaaatgc ggaaagatta ggatatcaca
     9001 acactcgata tgaagtcggg acagcagagc aagttctgcc taaatggttg aatgaaggtt
     9061 ttcagcctga tggtatcatc gtagatccac cacgtacggg tttggataac gcattgatcc
     9121 aatcattatt gaaataccct ccaaaaaaac ttgtttatat ctcctgtaat gtttctacac
     9181 ttgccagaga tctggttaat ttaagtaaaa agttcaagat tgaatattta cagtctgtcg
     9241 acatgtttcc tcagactgca cgttgtgaag ttgtcgtgaa gatgacgaga ctcgctgact
     9301 aaatgaaaga ggttgtgaaa aagtctgccc tgtatcaagt aataagaaca gccaaacaaa
     9361 aatagctctt catgttttat gaataccgta cttgtgaccg aagagttaac aggaggacac
     9421 tatttattta aaaaaagggt tgtgacatag tttttgtcac agcccttttt gattattatt
     9481 ggatattcac gtctatcact tgataaaatg catttgtcgt atcgctgata ttccatactg
     9541 ctaaaatcac attatatcct tttcgatcct gcggaagtgt gatcgtttgg ttgactgttt
     9601 ttggtggaac agttgctttg tcgtctattt ttgtgatcaa ttcaaaatca ctaaatttca
     9661 aaggttgatt aggattccaa gttggtttgg taatgtagta atcccaagta cttgtccgat
     9721 gttgtgctgt taaattccaa gtaatattta atgttcctgg attaaccatg tttttatgcc
     9781 atctgttaga tgtctgttca tctaaaggct caaagccgct gactcctgca ctagcaattt
     9841 ttccatcaat gaatgtattt ttggtagctt cgatactttg cggttcccat tgtgctcttc
     9901 cgacattttg atttaagttt cctgctgctg atgttcctag gtatgcacgg cttcctggag
     9961 aagtaatata accatgcgca aaacctggaa tgctaaaacc gaacaaccct aaactaacta
    10021 acccaataaa caataacgta ctaatctttt tcatgtagaa acctccttca tttgataacc
    10081 acattgtaaa cgctttattg tattaacaca aacattatgc ttttataatt ttatgttgaa
    10141 gtaaaaaagg tgaaaaaagt aagatgcaga ttataacaga agtagacgag aaaagtacaa
    10201 atagaaaaca tgagaaccaa atcatatgat ctttttcaaa aacatcattc atataaacaa
    10261 atgttcaact ttttaataac aacaatcatc aatttttttc ttacttcaca aactaaatac
    10321 aggtcttgct gtgagccttc atggtaaact actattatag aaaggagtta gtaaaatgaa
    10381 gatgataaaa gatattcgtt tttgggtttg tgttatagga attgtcatat taggcttttt
    10441 atcagggttg cttagcggaa atcccggaga atattactat tctttgcaac ttccaccatt
    10501 tgcaccacct agctggatat ttgggccgat gtggacctta ctgtatatat tgatgggtat
    10561 ttctctttat ttgttactta atcacaacaa caaaaaacag cgaaacaatc ttgtcggtct
    10621 ttttgtgatt cagttcattt ttaattttat atggtctgct ctatttttta atttaagaaa
    10681 tattttcatt gcagcaatcg atattacact tttagttatt ttcttgtcag tgcttatgta
    10741 tcagttgtgg ctacatcatc gcctggcaat gtggctcatg attccttatt atttatgggt
    10801 actattcgca actctattga attattcaat ttatttttta aactaagcgc taaaaagaga
    10861 cgtcctgtaa tttaacacat agaaaaagtg ccacctaagt tagatttttt gtctaattta
    10921 ggtggcactc tttattaacc aaactatttt tttctagtac ccacttgttg ttccatactc
    10981 attattctgg tcataaccat aaccattttg ttcctgtcca gcgtaaggat cataactttg
    11041 agtatcttga cttggtgtat agtactgact tgtatcttct gtttgctgat aataggtatt
    11101 cggatcttgg tactgatcat atgtgttttc tgaataggaa gaataatcgg tgtacccttc
    11161 actattcgat ccatcaccgt ttgtcgaatc gccatcttcc gaatcatcaa agaacatcat
    11221 tgaagcattc tcatttttca aattaggtaa tgtatcgctt gtttttatat ttaattgttt
    11281 cttcagttca ttttggatcg aaagaagatc attttttcct aaaatttgat agtagatatc
    11341 attgatcatt tgtccttcgc cttgcaactg gtcttgtttg attgtttcaa acgcaggggt
    11401 gtagttcgtc gctacatcaa gcatgtcatc ccaatctaag tccgtcgtca cattgttctc
    11461 aactgctttt aaaatttttc tataattgct tacgccatct aaacttaaaa ctttattgac
    11521 gattttcgtc actacttccc gctgacgacg ttgtcgaccg atatcgcctt ctggatcttc
    11581 gtgtcgcatt cgagaatagg ctaaaccttt ttctccattc aatgtttgtt cacctactgg
    11641 tacatggaca ccatccaaag taaagtcaat tttattattc actttgatgc caccgaccgc
    11701 attgatcaaa tcttccatgc catccaaatt gatcgttaca taatgatcaa taggaatatc
    11761 gagcagttgc tcaattgaat ccatggccat ttcgacacca ccaaatgcat aggcatgatt
    11821 taatttatct accgttccat aacctacgat attcgtataa atatctcggt ccaaactgat
    11881 gatcgttgat tttttttgtt tcggattaac tgttactacc atcatcgtat cagaacgtcc
    11941 ttgttccgtt cttcctaatc caccggtatc taaacctaat agcaaaaccg aaaaaggttc
    12001 tttgtcatca atgcttactc tctcagaacg tttggaggat attcgattag agtttttaga
    12061 aattttgttt actgtttggc tcgcttctcc cataaatctg attccgtatg ctgataatcc
    12121 ggcaatcagc aaaacaaata cccctaacaa ggttaataga actttttgcc atcgcttcat
    12181 aatacacctc tgtttcacat tttctaaaat attgtctcat ataactgttc aatcagcaaa
    12241 ttcacttttt aatcataaga aaactttaaa aaacattttt gtgtaacgat tactattttt
    12301 taaaatttct caaaattctt aactatcata ccataccgtg aaaaagatcg aaagaccgaa
    12361 tacacgcagt tcgcaatcgt tttatctttt tttacgtatt ttttccagaa aaagcgaaca
    12421 acaaggtatt ttccaaataa tcgtgcagta aaatgatcgc acataccttt cccatctttt
    12481 taacagtctt tgcctaccgt tcagattatc attcgatttc acgaaaattt cttcctatga
    12541 ctggtccttt tgttaaaccc atcttctatt cgttttattt ccagctcact gcatggctct
    12601 taaaatgact cgaactagtg atttcattac catcatcttt taatggatag atatgctcct
    12661 cttcaaagta aaacgatttt cttttaaagt aatagaattg acatggtaat gagtatgtat
    12721 actagtggtt tcacaaatgg tcttttattc aacatccaaa aactgaaatt tctttaaaat
    12781 ccattactaa cgaagaaaat gttccttgct tgataattag ttaggacatg tcaagtgaac
    12841 aaatgcattt acttagccaa aaaatctaaa aacttcataa atagacaaaa agacacgact
    12901 ctctaagaag tcgtgtcttt attcaacaaa ttattataat ttagtcactt cagcagcttg
    12961 aggtccgcgt gcaccttcaa caatcgtgaa ttctacttct tgaccttctt ctaggctctt
    13021 gaagccgtct ccttgaattg ctgagaaatg aacaaatacg tcatctccgc cgtctactgt
    13081 aataaaccca aatccttttt cattgttgaa ccatttaacc gttccgtgtt ccataaatgt
    13141 atagcctcca aaaaagttct tgcaagtaac cttgcaagaa cattataccc aatttagaaa
    13201 acgctagcaa gctttcgctc ttttattttc caaattattt ttaagactga tatgacggag
    13261 gaaatggtta ttttgctgct tcgaaacgtt tgtttacttc atcccaatta ataacattcc
    13321 agaatgctgc aatataatct ggtcggacat ttttatattt caaataataa gcatgttccc
    13381 aaacgtccaa acctagaatt ggtgtctttc cttccatcaa tggagaatct tgatttgcag
    13441 tagaggtaat agctaatttt ccattttcca ttacaagcca agcccatcca gaaccaaatc
    13501 gtccagcggc tgcttttttg aattcttctt taaaagaaga aaaatcacca aaagcttcat
    13561 taatcgcttc ttttatttct cctgtaggtt cgccaccagc atttggtgcc atgatttccc
    13621 agaaaaatga atggttagca tgtccgccac cattgttacg tacagctgtc ttgatatctg
    13681 ttggaatagc gtccatatca gataataatt cttctattgt tttttcgcct aattctgggt
    13741 atttctcaat tgctgcattt aaattcgtca cataagtatt gtgatgctta tcatgatgca
    13801 gatgcatcgt ttcttcgtca atataaggtt ccaatgcgtc atatgcataa ggtagatctg
    13861 gtaatgtgta agtcataaaa aaattcctcc tcaatgtttt ctttataatg tctacattac
    13921 aaagagtaac aaagagaagg aaattcttca attgttatgc ctagtcgtct ttttcacttt
    13981 gacctacttc ttcttcaaaa acctcagttt ctttaaaaat aaacaacttg ctgaaaatat
    14041 agttcgctag gataacaata atttgagtga tgattttcgc cacatactca ttgctgttca
    14101 taacattgat caacaatacc attgccccca tgtccaatcc gtaagaaagg atacggtaga
    14161 agaagaactt accgcattca ataagtgcat gtgtaaaatt cggtgatttt gaatggaata
    14221 cccaaagttt gttcgttaca aaagcaaaca atacagaaca aaaccacgaa atagaattgg
    14281 ataaggccat acttaaatca aaatattggc gtgcgagagc aaaactaaca aaatttacaa
    14341 tcgtagccaa accaccaaaa aagagataga ctagtatctc ccaatatcct tttgcttcta
    14401 aatatccttt taactgtcga tactgcttca tgagccaacc taccttatta aaaattctta
    14461 tttatcatac tctatatttc aataactttc atctttattt aaaaaaatta attttttttg
    14521 atcctttgcc tttgtctctg cttggatcgt cacatgtgta ataccatatt ttaattttaa
    14581 taaagaaatt atacgaggat atatcttttc aatctcgctt agtagctgat cttcaaaatc
    14641 aatatgtccg tcgaaaataa ttatcttttc gctatactgc caaatatgga catgatgaac
    14701 attctttacc ccatcgattg cttcaatttc ttgttccatt ttttcatagt caatagcagg
    14761 tgcactttgt atcaaaatag cggcagcttt tttgatcacc attatcgctt ctatcaatat
    14821 atatatcgaa atgatcagtg taataactgg atcgatccag tagatatcga aaaaacggat
    14881 caaaattgct ccgataatca cacttaccga agacagtgta tcacttaaca aatgcaaata
    14941 actagatttt atattcaaac tttcatctgc ttcttgtcgt aataataata ctgagaacaa
    15001 attcgcgagc aatccaataa ctgctactgt tagcatcaaa tgactattta tcttttctgg
    15061 tgaagtgaac cgcttgaatg cttcaacggt taaaaacaag gataatatga tcaatatgaa
    15121 tgagttgatg aaagcactca atatttctaa acgctggtag ccatacgtac gttttttatt
    15181 tgcttctttt cgggccattt tttgtgcccc gtaagaaaaa ataattgcca atgtatcact
    15241 aaggttatgg aaagcatctg aaacaagaga caaactccct gacataatcc ctccaataaa
    15301 ttctgataaa gtgatcaccg cattcaaaac cactactcca aatagttttt ttgatgatct
    15361 ctgtggctgt gtaggcacta ttccttcctc cattttattt atattggata gtctttagac
    15421 aagaataaca tttttttgat atttcaccaa tcattcagat gtttccctaa agcacttgta
    15481 tttcacttga tacttcgcta gaattgcaag tgatgacact actagatgag gagtacttat
    15541 gacaacaaaa caattaatta tcagttcctt tatacgattc aaagacctaa aggaggcgag
    15601 aaatgtccca ttttggaaag ccattgtcta tcttttagtt ttgagtataa ttatggcttt
    15661 gccaatctct tttcaagttt ttcaagtctt aaataacatt caattggatg ggcaaaagat
    15721 tgctactcgc attcctgatt ttacaatcca aaacgggcag cttcaaaccg aagaaaaaga
    15781 aggattcatt taccaaacaa actccattat cttcacattt gatccagagg gaaaacgaac
    15841 agaacaggac atctctactg atttgatggg gaattttgtt agtgtcggga tgttaaaaaa
    15901 caaacttatc atagctcttc ctaatacagg cacgacttct gctttgttga acaataacca
    15961 attagaactt ccctacacca atgaatcttt aaaaaactta acaggtaagc agctccgttc
    16021 ttttttaagt gaagcatcta taccactttg gataaaagtc ctgacattta tattttctat
    16081 ttatcctagt tttctgaatc tgctgatcac tttgctattt accaacattg ctgcttttct
    16141 ctatgcacgc tttcgactaa caaaagctac ttttcttgat tgtttaaaaa cattgatcta
    16201 ttcaatttca ttgcctacta taattgcaac aatcttgatg gtctttcttc cttcttttga
    16261 cactagcgcc ttcattgctt ttgcaggaat ctttattttt gctcaagctg tcaaaggatg
    16321 ggcaaaaata tcgatcaatt aagaaataaa gacaactcgt tatttctact taaatagacc
    16381 cttttagagg ttgtgacatt tttttgtcac agcccctttt ttatttgaaa aatatttctt
    16441 tctcaaaaaa caagcaaggc gcttcaaagt tcttcttgta tgcgctacac ttagagtaaa
    16501 gaaaggcggg aaattaacta tgtcagaaag aatcatttat gcagatcgtc catttcgtga
    16561 tgaatttatc gaagaaatcc atactatagc gcctggttat atctttaaaa cagaattaca
    16621 accagaggat ctacaaaatg tagagatcag tttgggctgg aactcagact accaagaaaa
    16681 actattagcc tcttctacct tgaaatgggt ccaatctatc tcagctggtg ttgatcagct
    16741 accccttgag actttttcaa agaaacatat tttactttca aatggtagtg gcatccacag
    16801 tgaatcgatt acggagcatg tcttaggaat catccttggg tattctcgtg gtctttttca
    16861 agcacaaaag gcacagagtg acatgaaatg gttaggttca tcggtccatt accaatctat
    16921 ccaagggaaa aaaatactaa tcattggaac tggccatatt ggaaaaatga ttgcaaaaaa
    16981 atgcaaagca ttagacatga actgctatgg aatcaataca tccggtcatc cagcagaagg
    17041 aatggaaaag actttttctt taaatcaact aaaggaagtt cttcctgaag tagatttcgt
    17101 agtcaatatc ttacctctaa cggaggaaac aactgggctc tttgatcagc atatgtttga
    17161 acactttgat ccaaaatctg tattcatcaa tgttggccgt ggtgcttctg ttaagacaca
    17221 agatctggtg caggctttaa ataaccagca actttccttt gcagcattag acgtttttga
    17281 ggaagagcct cttccacaag atcatcctct ttggaaaatg gacaatgtac tgattacttc
    17341 ccacattgca ggtttgacac ctgattttca aaagaaatta atggctattt ttttaaccaa
    17401 tctgaaaagc tactttgcca cccatgagct tcaaaccaat caagtaaaat tgtctgcagg
    17461 atattaatag ctgaaaacaa tattttcaaa agaaaaaaga gaaggtgaca aaaattgtgt
    17521 caccctctct ttttttattg ttttttaaag tgataggttg gctcctccag gttgggatca
    17581 taatcaacaa gtaaatcata tcctttaaag aaccattcat ctgcttcctc gataaaaaaa
    17641 agtgtcccat ccatttccac tttctttaca ggatgttctg gctgttcaac tgacattcca
    17701 atcgaaaaac catcatgaac ctctgttttg ccgtagactt ttccaaaaaa acgtattccg
    17761 taagtttctg gcagatcaat ttctgagtca aaccattttt gtgcttttgg cgttaccgtt
    17821 aatttcatcc caacaaccta ctttctcttt tctttctatt gattcatctt atcgtctaga
    17881 atatccacat cgcctgtctc tccaataacc agtagattat cattttcacg aacatattca
    17941 tctgctgcag gagaagcgat aaccgtttga tctactcttc gtatggcgac tactgttaag
    18001 tcaaaacgtt gcctgaaatt taattcagct aatgttttgt tgaaaaattt aggattggag
    18061 actcggattt ctgctaaaga atatttatct gacagctcta agtagtctag aatattcttt
    18121 gatactaagt tatgtgcaat ccgtatcccc atgtctcgct cagggtgtac gacacgatct
    18181 gctccgatct tctctagtac acgggcatgg tactcatttt gggcttttgc taaaatattc
    18241 ggtacgccca tttcctttac catcagagta actaagatgc tggcttggat atcttctcca
    18301 atagcgacaa ttacatgatc gaaatttctt atacctaatg aacgaagtgt catctcatcc
    18361 tgtgcatttg ccacaacagc atgggtggct atattcatat attcattgac tcgatcttca
    18421 ttactgtcaa tagccagtac ttcttgtcca gcttcgatca gtgtacggca gatgcttccg
    18481 ccaaatcgtc caaggcctac aattgcaaaa ttttgtttca ccattttcct cctttagtat
    18541 cttcttttct cagtataaca aagcctttcc aaaaacaaaa gcaagcatca ttattgtaaa
    18601 aaagccaaga aaaataatag ttattttctc agcttttgat tatcctcttt atcatcgttt
    18661 ttatttcacc aaaccatgtt taaacgcata gatagctgct tgagttcggt cttctacctc
    18721 taacttagct aatatattcg acacatgcgt tttgactgtt ttcagtgtga taaacaattc
    18781 atccgcgatt tcctgattac ttttcccttc agaaatcagc atcaaaattt cattttctcg
    18841 attcgttaat tcttcatgca atactggatc atttcgccga ctcatttttt ccatcatttt
    18901 tgttgtcact tcaggttcta gtactcgctc gccgcgttgc gtagccctta tagcatcagc
    18961 tatttcatgt gctgtagacg tcttcaacaa atatcctgct gctcctgctt caattgcagg
    19021 ataaactttt tcatcatcaa taaaacttgt gacgataatg attttggctt ttggccaatc
    19081 ttttaagatt gcttttgttg attcgatgcc atccatttct tccatgacta gatccattaa
    19141 aatgacatcc ggtcgaagtg ccatcgcctt ttcatagcct tgacgtccat tttcagcttc
    19201 tccaatcact tcaatgtctt cttggataga taaataagaa gagacgccta agcgtaccat
    19261 ttcatggtca tctactaata aaacttttat catctttatc tatgcctcct tcatcaaagg
    19321 gaccttggtc tccacgctcg taccttgccc tttaaaacta atgattttta ctgttccacc
    19381 aataccagct actcgttctt tgatattgtt caatccataa cttcccgttt tggtttcatt
    19441 catattaaat cctgtcccgt cgtcaatgat acgtaataaa agattgttat ctattttatg
    19501 caaatagact tctaattcat tagccttagc atgtcttaat gtgtttgata acaattcttg
    19561 aacgattcgg aacaagtgat cctcaatgga actagttaat tttacatctt ctacctccca
    19621 ttttagcgaa atctggattt tattctgcaa ttccttcaat aactgctcaa tgccttgttt
    19681 taaacttttt tcttctaaat tgactggacg cagatgaaga agcagcgcac gcatctcaga
    19741 ctgggaagcg ttgatgatct ctgccaccat tttcaactgc ttacggaaca tttctggtgt
    19801 ctcacttttt tctgcttgct ccgtcaatgc cgacatcatc atcatcgctg caaataattg
    19861 ctgtgaaact gaatcatgaa gctcacgagc taatcgatgc ctttctaatt ttaaaatctc
    19921 ttctttggtt tgtccatcta catattgagg acggctagtc ataatctgta attcactgga
    19981 tacttcgatc attttttctt ttattttagt aatttccata tcaatatctt tgatgtacag
    20041 atcatccgac gcgcttggga tcggctgatg caaaagtttg gattcataat tgccagaaga
    20101 aagtgcacga agcttttctt cgattttccc gtattttgcc ttttgaataa gtgataacaa
    20161 tagaaatacg atcaatccta cacctaatga aattgccatc aaatggaaga taagcggaac
    20221 gtataataaa cgcgcacgca gcaattctcc ccaccaatga ctttggttac tggcataaaa
    20281 ataagtgaaa agtgaaaata gaataataag gaaagccgca atccccgaat aaacagctag
    20341 cattgctttg gatattcttc ccatcatatt cgtatcacct cgacatctcc aaccaaagta
    20401 ttggtaatga tcttcaatct gcgaggattt tcatcataat cactgctgca gattttgatc
    20461 tgttcgtttt ttaaggaaaa ctgctcttct tcaaacaaga catttcctac taatgtcgca
    20521 tgctctaaac gaatagccac tcccaggggt actaagatcc gtgttctgcc tatccctttt
    20581 cttacaatca caatattatc atcttttggc aaaagtgtat tgcccaaatc gatgatagta
    20641 tcaccagaaa tgatggcaat gttgatatca tcccattcat agacgtcgtt tccaatacgt
    20701 tggttaccaa ataattgctg tcttttacgc tcattattat gtgtttttaa ttgctctgtt
    20761 tggaccatca tgatctgttt ttttcgccaa aaagcatttt ttgtcaaatc tattcctgaa
    20821 atctctacac ctttcagccc gataaataaa acggccaata caaccatcat ccataaagca
    20881 ggactgttga ctaagctaaa aaaaatgacc aagctcccta agatcaattg aaaattttga
    20941 aatttagtac gaggatattt gcgcatagct agatatatat tgaaaatacc gaatattact
    21001 aaaagcaaaa gtccagtatt gtttacgatt tgccaaacag caaataacag cagcagtgct
    21061 tcgactacca caaaaaaacg ccaagaacta ttcatcgctt tttctccctc ctgacacatt
    21121 ctcatttcat catacctatt tttttgactg ttggctatag gactttagat gtaagatcgt
    21181 tcagtgaaac ctgcaatact caaagagaaa agatctagag tgcgtcatca gtaagatgaa
    21241 ctctctagat ctttcagtca gactacgctt gttctacttt gacgatttta actaacatat
    21301 cgccacctgg tgtagcaatg gttacttcat catttttacg tttgccaatc aatgcttgcg
    21361 cgataggaga atcattggaa atctttccag aaaacgggtc tgcttcagca cttccgacaa
    21421 tcgtgtactc ttcttcatct ccatcaggca actcgatgaa cgtaactgtt ttaccgatcg
    21481 atacctcatc tgcatctacg ccgtcattat cgatgatttg tgcaaaacgg atcatatttt
    21541 caattgttgt gattcttcct tcaacaaatg cttgttcatc tttagctgat tcgtattcgg
    21601 agttttcgga aagatctccg aaaccgcgag cgattttgat tcgttcaatg atttctccgc
    21661 gtttaactgt ttttagttct tctaattctt tttctaattt ttctttacct tctagagtca
    21721 ttggataaac tttctctacc atgtgtaacg tctccttttt tcgataaaat accgcaaaag
    21781 gtaatctttt gaggaatata gtccaaaaaa gattaccacg cttttcttaa aatgtaaatg
    21841 tttttctaaa aatgatcaat gactagcccc tgtttttcta agaattattt acatattttt
    21901 gcactagttc catatgttct tcatacgttt tagcgaaata aacatttcca gtgctcgtat
    21961 ctgctacgaa ataataatag tcattttctg ctggttctaa tactgccttg attgcctctt
    22021 cgcttggatt gtcaaaagga ccaggcccat agccggtatt ggtatacaaa ttgtatggtg
    22081 aatctacagc tgtatcttca tacgtcacca attctttatg ttctcctaat gcatataaaa
    22141 cagagatatc tgactgaagt ggcatatttg ccttgattcg gttaaagaag acttgtgcaa
    22201 tatttttacg atcattttct tttacgcctt ctttttcaac tagagaagcc aaagttaaaa
    22261 cttcttgtac agtcaaattt ttctgtttga tagctgaata atagttttgc atgaccgtat
    22321 ttgttttgtt caccatctca atcacaagat ccttaagcga agtactcgtg tagtaatcat
    22381 aagtagctgg gaataagtag ccttccaaac ggtattttgt gttctcagct ttagaggcac
    22441 tttccaacaa ttctgggaat ttttgataca actcgttaaa gaaagtctca tcatttacta
    22501 aatctaaaaa ttctttcttg tctttaccag ttaccttcgc tacccgctca gcaatctgat
    22561 cgatgtcgta gccttctgga atggcaattt tcccatctgc aacttttgtt ggctcagaag
    22621 tgccgccttc ttgcagctgt ttgccaatct cgtcaagagt catattaggc gctaactgat
    22681 aatagccagc ttgaaagcca gttaaatttt taaattttgt ataataattg aaaacaatcc
    22741 cgcttttaat aatattgtcc ttctccaaaa tctcaccaat ctgcttgtta gaagagccac
    22801 tcgggatctc cacttggact aattggtcat ctgatttatc taaaggcttc aacccgctat
    22861 ctacataacg atacacggta aatccaagaa atccgccaat aattaataat gtaagagcaa
    22921 tcactaaaat gatcttcctc acaatcttat cttctttttt acgcagattt ctccgcttgt
    22981 cgattatatc tgctgtagct gccttactgg cttctttttt atctttactt gggtgttgtt
    23041 tgtttcctga caaaacaact cctccttact atcatcttcg taactctgtt tattatacat
    23101 gaaatttcta ctgccgtgaa ttattttacc aaatattatg tcaaaattgt aagtggcaaa
    23161 tactcttttt gaggattaca atgaaaaata gttaaaaatg gatagaaagg aattaacatg
    23221 tcaaaaggaa aacatcgaaa aaaacaaaaa atttctattt cttttcttgt aattttatta
    23281 ttgtctgtca gcttcttttc aacaggcatc attataggag gtcaattaac aaaaatacct
    23341 cattcccaaa cttataaagc ggagccaaca caacttactt ccaatttaac gcccgatgag
    23401 cagaggcttg ctagcaaaat tgatcaatta ctacaaaaat cagattatat cggttcgatt
    23461 tatgttcgca aaaataatcg cgtactatta gaaaaaggat atggatatgc aaatctgcgc
    23521 gtaaaagaat cgaattcacc ttctatttac tatcaaatcg gttcgattca aaaagcaatg
    23581 actgctttac tgatactaaa acaaatccaa gctggtaagt taacttttga cacaaagtta
    23641 gcagaatttt atcctcagat tcctggaagt cagcaaatca caatcaaaaa tatgctttat
    23701 atgcgctctg gtcttcatcg aactgcttct cccgacaaac ctatgtcgga tagtgaaatc
    23761 attcagttcg cccttcatca tttgaaactt actgattatg atacgtatca ttatgaacca
    23821 ttgaattata cattgcttac agggatattg atcaaactaa cgaatcagcc ttatgaaact
    23881 cttctaaaaa aagaaatcat tcgtccactc catctagaac atacagattt ttatgacaat
    23941 gtaaaaaatt cgcctcaaca tgctgtatct taccagatgt ctgcaactga cgattattca
    24001 aaagcattga tcgagcctga aaccgacatc cgaaatgaat taggtacagg aaacataagt
    24061 atgtctgttt atgacttgaa caaattcttt accagtgttc tttctggcgg tatcatacca
    24121 aaagaactac ttttctcatt gtggcaaaat aatggtgata aacatcctta cagcggcggt
    24181 gtttacagtg gaaacgatta tatccttgct caggggaata tcaatcgatt ccatgcagta
    24241 gtggcgatga aaaaagacac taaagatgca atcgtcatgg aaagtaatat ccaatcggat
    24301 aagaacatca aattgccggc cactgattta agaaatcaga tttatgaact gatggaaggt
    24361 gttcacttat caaattaaat tttgacataa tattagttgt catctctgta tagtcaattt
    24421 agttagtact ctatctgaaa agtagaaata aattaacaaa tattatctgt ccttattatt
    24481 tgttaattta tttcttattt ta
//
LOCUS       DAXQKX010000037        24072 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.037, whole genome shotgun sequence.
ACCESSION   DAXQKX010000037 DAXQKX010000000
VERSION     DAXQKX010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24072)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24072)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24072
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.037"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..240
                     /locus_tag="ACF3MF_001705"
     CDS             <1..240
                     /locus_tag="ACF3MF_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFE3927693.1"
                     /translation="YNTGKELARVRADGIYRPDVNQAYNTLGNVGYHVSFNMRNFPNK
                     KVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
     gene            543..950
                     /locus_tag="ACF3MF_001706"
     CDS             543..950
                     /locus_tag="ACF3MF_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927694.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            964..1365
                     /locus_tag="ACF3MF_001707"
     CDS             964..1365
                     /locus_tag="ACF3MF_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927695.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1367..1738
                     /locus_tag="ACF3MF_001708"
     CDS             1367..1738
                     /locus_tag="ACF3MF_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927696.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(1774..2076)
                     /locus_tag="ACF3MF_001709"
     CDS             complement(1774..2076)
                     /locus_tag="ACF3MF_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFE3927697.1"
                     /translation="MLMEGKTQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINL
                     YYSNKNYFKIPAAKTRMKKGVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(2334..2447)
                     /locus_tag="ACF3MF_001710"
                     /pseudo
     CDS             complement(2334..2447)
                     /locus_tag="ACF3MF_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(2830..4062)
                     /locus_tag="ACF3MF_001711"
     CDS             complement(2830..4062)
                     /locus_tag="ACF3MF_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HFE3927698.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            4316..4885
                     /locus_tag="ACF3MF_001712"
     CDS             4316..4885
                     /locus_tag="ACF3MF_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFE3927699.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(5063..5503)
                     /locus_tag="ACF3MF_001713"
     CDS             complement(5063..5503)
                     /locus_tag="ACF3MF_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HFE3927700.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            5661..6425
                     /gene="map"
                     /locus_tag="ACF3MF_001714"
     CDS             5661..6425
                     /gene="map"
                     /locus_tag="ACF3MF_001714"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HFE3927701.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            6457..7380
                     /locus_tag="ACF3MF_001715"
     CDS             6457..7380
                     /locus_tag="ACF3MF_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HFE3927702.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            7456..8595
                     /locus_tag="ACF3MF_001716"
     CDS             7456..8595
                     /locus_tag="ACF3MF_001716"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MraY family glycosyltransferase"
                     /protein_id="HFE3927703.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            8588..9388
                     /locus_tag="ACF3MF_001717"
     CDS             8588..9388
                     /locus_tag="ACF3MF_001717"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFE3927704.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            9388..10215
                     /locus_tag="ACF3MF_001718"
     CDS             9388..10215
                     /locus_tag="ACF3MF_001718"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFE3927705.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            10220..10927
                     /locus_tag="ACF3MF_001719"
     CDS             10220..10927
                     /locus_tag="ACF3MF_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFE3927706.1"
                     /translation="MRSVCIATFNGGRYLREQLDSILSQLSAEDEVVISDDGSVDDTW
                     DILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWLETKVKKITD
                     YFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYIGAGMAFRSS
                     LKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIETHSKLRQKIS
                     WRVHLITALIKRKWFKR"
     gene            11027..11893
                     /gene="rfbA"
                     /locus_tag="ACF3MF_001720"
     CDS             11027..11893
                     /gene="rfbA"
                     /locus_tag="ACF3MF_001720"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HFE3927707.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            11907..12479
                     /gene="rfbC"
                     /locus_tag="ACF3MF_001721"
     CDS             11907..12479
                     /gene="rfbC"
                     /locus_tag="ACF3MF_001721"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HFE3927708.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            12501..13529
                     /gene="rfbB"
                     /locus_tag="ACF3MF_001722"
     CDS             12501..13529
                     /gene="rfbB"
                     /locus_tag="ACF3MF_001722"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HFE3927709.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTSILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWQPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            13627..14478
                     /gene="rfbD"
                     /locus_tag="ACF3MF_001723"
     CDS             13627..14478
                     /gene="rfbD"
                     /locus_tag="ACF3MF_001723"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HFE3927710.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLPYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEALGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            14513..16546
                     /locus_tag="ACF3MF_001724"
     CDS             14513..16546
                     /locus_tag="ACF3MF_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927711.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFSLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMIAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFVALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            16590..17870
                     /locus_tag="ACF3MF_001725"
     CDS             16590..17870
                     /locus_tag="ACF3MF_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HFE3927712.1"
                     /translation="MKIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGVGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFTVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNTIGSSLMTLALLISGFASSFERWYVRIIGGIAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQVLLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVTEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            18080..18886
                     /locus_tag="ACF3MF_001726"
     CDS             18080..18886
                     /locus_tag="ACF3MF_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFE3927713.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            18898..20118
                     /locus_tag="ACF3MF_001727"
     CDS             18898..20118
                     /locus_tag="ACF3MF_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3927714.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGKVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            20108..21694
                     /locus_tag="ACF3MF_001728"
     CDS             20108..21694
                     /locus_tag="ACF3MF_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFE3927715.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLYINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAQPQNSNYVKVLEVIQQTKQDEIIQQIPFNNFTGENETLSFHVSELA
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKDLPEFFLTDIAG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHYLIENNTRLD
                     QTLKTTINRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSLCIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVLREEVNQAKQLAEGAKAGFELRILCEK
                     ERSFLVEAVAQNGQSWIIEM"
     gene            21733..23871
                     /locus_tag="ACF3MF_001729"
     CDS             21733..23871
                     /locus_tag="ACF3MF_001729"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFE3927716.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEVQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRQENGHISLATNSALKMAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDLIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPAEHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVHPGRISGFYEITYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYPNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTAMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     ILEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPSYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(23939..>24072)
                     /locus_tag="ACF3MF_001730"
     CDS             complement(23939..>24072)
                     /locus_tag="ACF3MF_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFE3927717.1"
                     /translation="VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
BASE COUNT         7708 a         3999 c         4924 g         7441 t
ORIGIN      
        1 tacaatactg gaaaagaatt agctcgagta agagctgatg gaatttatag accagatgta
       61 aatcaagctt ataatacttt aggaaatgtt ggctatcatg tatctttcaa tatgcgtaat
      121 tttcctaata agaaagtcta tgtaatgatg cgggcaacga atgatccaga agggaacact
      181 aaaggcggag cacaagattt tcatgataaa cgctggtact tgaatattcc taaacgataa
      241 aaatagcccc tcatttttga ggggaagtac atatagttgt tgatatagtt gctaatattg
      301 ttagctaatt tgttagtaaa actgcatact atttagatag taaaaaaaca gtttgttcct
      361 tatatagagg cacttttact actgattaaa tgtcagatat gcttacaaat atacttataa
      421 atatgcttac aaaattagct aatatttccg ttgacaaagc tttgttacta ttgttaaact
      481 aaattgacta gcaaaagtga aacataaatt tattaaataa atgtaaaaat taggagaaat
      541 caatgtctta tagagtacaa ttaataattt cagaagatgt agaaagtcag caatttggca
      601 ctaatgttat taataaagta attaatccag ctctttctat taatgcgcct ttaattccta
      661 ctgctttatc attttctgta acagctgtgg tgtctgagat agaggataca gaaaagataa
      721 aaatagtaga aattgaagtt ttaaacaaga atgaaaaaca aattttttct acgggtgaag
      781 tatcggtaag cttgcctcct caagttaacg atataaactt taatataaac gccagaaatg
      841 tcttggttga agaagcagga gagcattatg ctgttgttaa atttaatgga actgagattg
      901 gaaggcaaat ctttgatatc aaggtcaaca aaccagtgga aaaaaattaa ggagacgata
      961 cggatgcttg atatagtacc atcaaataca catcggagtg gtagcttaat aaattttgct
     1021 gcgatttttg cttgcgcatc ggtaattcta gcatctccag ttgttgtgga tgcaagttct
     1081 actccgaaaa ctaaaaatga taatcaactt gtaattacta caaaaaatga gattaacaca
     1141 atttcaagta atgatggcaa aatttttgat gtgataaata cggttttaaa aagaaaagct
     1201 gaaatcaata taaaatatga tgaagattta aacttgtatt tctttgttat caaaacaaca
     1261 tctgaattgt tttcctcaga ttacgatgtt ttggatactc tcgataatgt attatctgac
     1321 tataaatata tggggaaatc tgtagtagca actttggggg aataaaatgt ttgactttaa
     1381 tgaatattta tctatttcca aacaaattga atcagatgat aaatataatt ctaaagaatc
     1441 ttatagaaga actgctgttt caagagcata ctacagtgct tttaaaaaat ctgatgagta
     1501 tttgaaagaa aattatgata ttatttataa tggaagtagc ggaaaaggaa gccaccaaac
     1561 cgtttggaat ttgttttcaa cagttaagga attgaatacc ttaggaatac ataatagtgg
     1621 gtatagaatg ttagagaaaa gaaaatgtgc tgactatatt cctaatgaaa ccattacgaa
     1681 aacagatatg gcgctgatga atcgagaagc agaaaaaata ataaacaaac tcacctaatg
     1741 aatttcaagc gagtttgttt gttatttttt tatttaatct ttgtatcttt ctggatcaac
     1801 gaaagtatac tttatatagt cataacgccg atgatcgcta cgtgcgtccg gcacgtcagt
     1861 cacgatatca aacaaaaagt atacaccctt cttcattcta gttttcgcag caggaatttt
     1921 gaaatagttc ttattagaat agtagagatt gattaataag ctatcttcga ttgctaaaaa
     1981 gaaaacttct gaattccata ctttataaaa atctttgata aatctattcg aagggtcaaa
     2041 tttaaaccat aattgtgttt ttccttccat cagcataaaa gttcacctca aaaagagtat
     2101 acgaacgaat gttctttttg tgaaggcgga atttaatata ctgaataata gaaaacaagt
     2161 acttgtgcca aattatgtgc caaaaaaatt cgaattcaac aaaatgtaaa caaatagaaa
     2221 accttctata ttaagatttc ctgcaataac aaacacaaca gaagacgtgt aatagttagt
     2281 caggaacgta caaataaccc ctgtatcctt tgcggtacag ggggttattt tgtataagta
     2341 gacattgtag tttctaaact gctatgtcct aaacgtttcg atacgctaag tatatttact
     2401 ccttgataaa gtaaaataga tgcatgcgta tgtcttagtc catcaataaa cagtcgaaga
     2461 gaaaataggg aaaaattgat tactaaagaa aaacttacta ggtcgacggt gtagttgatt
     2521 ttcatacttc aatagattcg aattaaacga tttcgattgg cttataccag tcctatccaa
     2581 cgaaagatat atcgttctta actctagcgg tataacttga agctttacgt aaagccaatg
     2641 ggaatgaact ggagatgact ttttattatt tttagtaata gctgatgggt taatacttac
     2701 aactttcctt ttcaaagtac catataaaaa aacggtgggg ttgtttagcg aaataaagga
     2761 tctaagccaa tagcttagat cctttattct atgctttata ttattttttg catgtgtgcg
     2821 aaagtatact caagcccaat cgccatttcg gaaaatcggt actgtagagc catcttcacg
     2881 gattccgtcg atatccatct tgtcagatcc taccatgaaa tctacgtggg tttgacttct
     2941 attcaatcca gcttctgcta attcttcatc ggacatttct gtaccgcctt tcacactgaa
     3001 ggcataagca gaacctagtg ctaagtgatt cgatgcgttt tcatcaaata atgtattgaa
     3061 aaagatgatg ccagattgag aaataggtga agggtcaggt acaagtgcga cttctcctaa
     3121 acgacgcgca ccttcatctg tatcaagcag ttttgctaag acatcttctc cttgttcggc
     3181 agaaaaatca acaacttttc catctttaaa agtaaatttc atacccgaga tgatggtgcc
     3241 agcataactc agtggctttg tacttgaaat gtaaccatct actcgatgac tgtcaggtgc
     3301 tgtgaacact tcttccgtcg gcatatttgc catgaatttt tctccacgag cattatagct
     3361 tccagcgcct tcccaaagat ggtttttagg caatccgata atgatatctg taccgggagc
     3421 agtatagtga agggcagaaa attgttctcg attcaattct tctgcttttt ttgctaattt
     3481 ttcatcatgc ttcttccatg ctaagacagg gtcttcttca tagacacgag tcgttttgaa
     3541 aatctgatcc cataatgcct caacttgttt ttcttctggc agttctggga agacttttgc
     3601 tgcccattgt ttaccagccg cagccacgac agtccaactg actttatttg cttgagttgc
     3661 cttgcgtaaa ttcattagtg ctttgccatt cgctgattga taagacgcta ctcgatggct
     3721 atctacacca gcaaatgcat cgggatcggc agaaacaacg ctgatcctgc ttgctccttt
     3781 ttcaagccat tcatccgctt gatcgatttt agattgtggt acattctcaa tacgatccgt
     3841 tgcagcatgt aaaagaaatt ctctttggat ctggtcgtca gtccattgaa cgataacctc
     3901 agcggctcct agtttataag cttcttgtgt gatcaatcga gcaaggggtg cctgttccac
     3961 gctgatctgt aaaacaactg tgtgtccttt ttctgtggct acgccagttt ctgcaattaa
     4021 gcgtgcatat ttttttagaa gttcattaaa atcagataac ataataaaaa ttcctcctca
     4081 ccattttttc tggtaactat tagcatgata ccatttaatt atgattcaaa caatgaggct
     4141 ttaaataaaa aaaggaggtt atttttttaa ggttaagttt catgatatat gttactactt
     4201 gctatttcag cttgtgaaga aaatcaaaaa ctaattttgc atatcaaaaa aacatgttac
     4261 aatgaaatta atcaatggtg gaagcgttat aaaaaaatta aggagattaa aaaatatggc
     4321 aagaaaaaag acgattacta gagaacagat tttggcagct gcttatgaag tagctgccac
     4381 cgatggattt acacgattta ctgcgagaaa catcgcgaac aaaatgaatt gttccacgca
     4441 accgatttat cttgagttta aaaatatgga tgacttgaga caagctcttt ttgagcagat
     4501 ctatgatcat ttacaatatg aagtgttcac tgttgagcat acagggaata cgattatcga
     4561 tcttgctttt aattatatcc attttgcaag aagagagaag aagttgtatc gttcactgta
     4621 cttagaagaa tatggtggag gaaaagagat gcagaatttc tcttatactt actttgtgaa
     4681 tacagtgaaa cgcgatccag cttatgtgaa tctttcagaa gagcagatcg aatctttgta
     4741 taatgggaca tggatcatag ctactgggat cgcagctttg atgtcttcaa gcatcatcca
     4801 tccaactgat gaacagattg aaaagatgat ccaagacagt atagatgcta tcttgaaatt
     4861 caaagaacca atcgaaatcg attgaatata ctcaaaagtt ccacaaatca gtaggtaaca
     4921 agagatgtgt caaaataagg aaaagttcgt ttttcttaca gcgtatgcat ttttaactcc
     4981 cgaagaactc ttccatgaat gcaatgaata aaagagccat acagattgaa taaatctgga
     5041 tggctctttt attgcaagta tattaaattt ttgcgactag ttctttagcg aaagcttcta
     5101 aattttcgat atcttcttct tcagcattca gatccacttt aacattttcg gctccttttg
     5161 atgcgcctgt ttttgcaaaa gcagcatcga aatcatccac cgatttgcag aattcatcgt
     5221 aaaaagtatc accagatccg cagacaccgt aaatttttcc caatagatcc aattcttgca
     5281 agtcttcata aaagtctacg atctcatcag gcagatcgcc atcatcgtat gtataagtag
     5341 ctactacgca aatatctgcc tcctcgaatt catctgcatc tacttgggta cattcgttga
     5401 tttcgacttc gatatccaga ttttcaaatg cttctgcaac aatatcggcg atttcttcag
     5461 tgtttcctgt catgctagca tatacgattt ttgctaaagc catgatgtgc ctcctcgttt
     5521 ataattattt aacaattatg aattatacca aaacatcatt gaaaagaaaa taaaacctaa
     5581 agacacctgg ggaatgtcat ttggctaaat gtatgccgct atgttaaaat gagagggatt
     5641 tgtaaaaagg agacgaaaat atgattactt taaaatcagc acgtgaaatt gaaatgatgg
     5701 cagaatctgg agctttatta gcagatgtac ataaaaatct gcgtgatttt ataaaaccag
     5761 gaatcacaag ttgggatatt gaggtatttg tcagaaacta tatcgagagt catggcggaa
     5821 ttgctgcgca aattggcttt gaagggtatg aatatgcgac ttgtatcagt ataaatgatg
     5881 aaatttgtca tggattccct cgtaaaaagc ctttgaaaaa cggtgatttg gtaaaagtcg
     5941 atatgtgtat cgatttgaaa ggcggcattt ctgattcttg ttgggcctat gtagttggag
     6001 aatctacacc tgagatcgac cgattgatgg aagtaacgaa gaaagctttg tacatcggta
     6061 ttgagcaagc acaagtaggg aatcggattg gtgacatcgg tcatgctatc caaacttatg
     6121 tagaaggcga aaatctagcg atcgttcgtg attttattgg tcatggcgtt ggtcctacga
     6181 ttcatgaaga accagcagtt cctcattacg gagaagctgg aaaagggttg cggttgaaag
     6241 aaggcatggt tatcacgatc gaacctatgg ttaataccgg aacttggaaa atgaaaatgg
     6301 atcctaacgg ctggactgcg tatacaagag acggcggact ttcttgccaa tatgaacata
     6361 cattggctat tactaaagat ggtccaagaa ttttgacatc acaaggagaa gaaggcactt
     6421 attgatctat ccagtcaata ggtacgggag aggtacatga aagtttggaa caaaataaaa
     6481 caaaatgaaa atctgatgcg ctttattgag acgactcaaa agcgcatcac tgattcagaa
     6541 atgagtacga cctctgtcgt cgttgcttat tatttactct tgtctttatt tccattgatt
     6601 attgcttttg gtaatatttt accgtttctc cacatcgatc aagagactgt actgacctat
     6661 ttacgagaag tgattcctga gaccgtttac cagtttatcg gtcctgcaat caaagacctt
     6721 ttgacacaaa gttcaggagg cttgttatcc gtttctgcat tagcggcttt atggtctgca
     6781 agtcaaagta tcaatgcttt gcaaattgcg atgaataaag cgtatggcgt agaaaataga
     6841 aaaaattttt tgatcgtccg tttcttctca ctaattgtca ttgtcttgtt catgattgct
     6901 attagtgggg taactatcgt tcttgggttg ggacagctga ttttggatgc tattcagcca
     6961 atcgtacaaa tacccgtgaa ctttatcgat cagttccaaa ctttgaagtg gccaatcaca
     7021 ttggtagctt tatttgtcat catgttcttg atttatttaa ttgtccctaa tgctcagttg
     7081 aagttgaaga cgatcattcc gggcacgatc ttcgctactg tcggctggat gctgttatca
     7141 caagtgttta gtatctatgc taggtatttt gcaacgagga tcagcggtta tcagatcata
     7201 ggaagtttta ttgtactcat gctttggctt aattttgctg ctacgatcat cattttgggc
     7261 ggaatcatca atgcagttgt tcaagaatac gtgacgggtc atcaaatcaa aaaacgtcga
     7321 gatccaagcc gaaaatggtt caataaattg aaaactaaat tttctcataa aaaaaagtag
     7381 aaacaagagt tcttattgta aatttatatc agtaatttat aataattatg actcttaatt
     7441 aaagtaggtg cccatatgct tgtttctttt agtatggtta taagattttt tctgacaatt
     7501 ttattatcac tgatattaac acctgtattc aaaatcattt cagtacaaac aggtatggtc
     7561 gacaaaccaa atgaaagaag aataaataaa gttccaatgc cttcagcggg cggactgcct
     7621 atctttattt catttgttat atcgacttta ttcttattcc gtaaaattat ccctcaatcg
     7681 tatattgtac cgatcttgat tgcttcttta gtaatcatag tcacaggagt gctcgatgat
     7741 aaatatgagc tgacacctaa acaaaaaagt atagggatct tgattgcttc tcttattatt
     7801 tattttgtag cagatatacg tattgattcc ttcacgcttc cttttattgg atatatccaa
     7861 ctaggctggc ttagttttcc cgtaacgatt ttttggatct tcggtatcac gaatgcggtc
     7921 aatctgattg acggtttgga tgggctggcg gcagggattt cattgatcgg tttaattacg
     7981 ataggaatca ttggatattt tttcctccat gcttctacag tgtatattcc agttgttatt
     8041 ttctgtcttg tagcaagtat tatcggtttt tttccttaca atttttatcc ggcaaagatt
     8101 tatttaggcg atacaggagc tctattccta gggtttatga tggccgtcct ttcactacaa
     8161 gggctgaaga acgtgacttt tgtttcatcg atttctttgc tgatcgtcat gggagtgccg
     8221 gtaacagaca cgttttttgc tatcattagg agaaaagcaa accgtgtttc tttttctaca
     8281 gcagataaaa aacatcttca tcaccgacta atcagtttag gctttactca taaaggtgct
     8341 gtcctgacga tttatgcgat ggctttgatg ttttctttca cagctatggt catgaattat
     8401 actggaagaa tcggaacgat catattgatt attgccatgt tgtttgctgc aattttatta
     8461 tttgaattga ttggtctgat caatgagaaa catcagttta ttttaaaaac attgcgattt
     8521 ttagggaata aagagtaccg tacgcaagta aaacagaaat atttgaagaa atggaaccgt
     8581 catatagatg aataacaaat taaaccagcc gatccttatt agtattgtga cggcaaacag
     8641 tgataaaatt tttcggacac tagataattt tatttcaact gtaaaagatg aaacagcagt
     8701 aaaaatccga atttttgaca acaattcact tcccgagtac aaaaaaagac taacagagta
     8761 taggaaatat ccctacatcg atatctattt tcatgatgaa aattccggat ttggttatgg
     8821 acataatcac aatctgatag ctagcgattc tcgctatggc attatttgta acccagatat
     8881 tttagtggat gaagagacag ttacagcatt ggtcttgtta ttgaaagaac atccggaatg
     8941 tgcgatgtta gcacctaaga ttcttaatga agatggaaca actcagcacc tcatccgtga
     9001 gcagctggct gtttttgatt acgttttgcg ctttgtgcct ttcaaatggg tcaaaaaaaa
     9061 gtttgacaaa cgactggctg tgtttgaatg ccgaggattg cctactgatg ctaatagtta
     9121 tgtacggatg atctcaggta gttttatggt agctgatatt gataaattta aagagataaa
     9181 ggggtttgat gagcgtttct tcatgtactt tgaagacaac gacttgtgtt tgagttttga
     9241 aaaagcaggt tacaagttat tgtacacacc cttttatgca gttatccatt tttacgggaa
     9301 gggtgcgcat cgaaatgcaa aactgtttcg cgtgtttttg acttctatga tgaaattttt
     9361 caataagtgg gggtggcgtt ttttctgatg aaaccagaaa tattagtagt cgttgtgctt
     9421 tatcagcaac tattcagtca atctccagct tatggaccat taagcaaagc acttagcgaa
     9481 aagcaaattc agcttattat ttacgataat agtcctcaaa ggcagcaaaa tgagctgttt
     9541 gaaaaagaaa atatcgttta tcatcatgat ccgcaaaatc ctggtttagc ggtggcttat
     9601 aattttgcgt tgtctcaagc agatgaagga acacgttgtc tcgtcactct ggatcaggat
     9661 acgaggctag tcgacgatta ttttgaacta ttgcgtaaag taacctttac agatgaatgt
     9721 gttgctgcag ttccgatgat tttttctggg agccgacaag tttctcccct atattcagat
     9781 cgttatatca atcgtacagc tcaagcagta gaagttgaag gcccaacagc tgaacgaatc
     9841 atggcaatca attcaggtgt tgcctggtct gtcaaatttc taaaaaagat tggcgggttt
     9901 aatcctgctt tttctttaga ttttttggat cattggctgt tttggaaagt ggatcagttg
     9961 gaaaaaactg tggagatcct tcctgtacga atggaacatg atctttcggt tttagactat
    10021 gaaaaagttt caagtaatcg ataccgttct attttacaag cagaaaatcg attttatcat
    10081 gaatatgatc aaaggcattt atccagtcac cgacgacaat tattgttaag aacagctaaa
    10141 cagttcttga ccgtcaaaaa ccggcatatc tggcggatga ctttgcgctc atatgttaag
    10201 aattggaagg tgtgaattcg tgcgttcggt ttgtatagct acctttaatg gaggcagata
    10261 tttaagagag cagttagata gtattttatc tcagctttca gcagaagatg aagtagtcat
    10321 ttctgatgat gggtcagtag atgatacatg ggatatatta actgaatacg cagaaaaaga
    10381 taagcgaatc cagctttttt cggggcctcg tcaaggattg atcgctaatt ttggttatgc
    10441 gatccagcag acgaaaggag atctaatctt tttggcagac caagatgatg tttggttgga
    10501 gacaaaagtg aaaaagatca ctgactattt tgagcagaat ccggatcagc tagtagtagt
    10561 ttctgattta atcattgtgg acagcgagct gcaagagatc catgattcgt atttttcgtt
    10621 tcgaaattcc aaagaaggat ggcttaataa tgtgataaga agtcactata ttggtgctgg
    10681 tatggctttc cggtcttctt taaaacccga tattttgccg atcccgtcag aagtgccgat
    10741 gcatgatatg tggattggtt tgctgggagg aaagaagact gggttcctaa gagaaccgtt
    10801 aactctgtac cgaagacatg atttaaacgc gagtgagatt gaaacacatt ctaaattacg
    10861 gcaaaaaatt tcttggcgtg ttcatctgat tacggcgttg atcaaacgaa aatggtttaa
    10921 acgttgataa aagatgttta aatccttaat atttccatga caaatataac aattgatgag
    10981 ataataacaa agtgaaattt gaaatcaaaa aggagagcag atatccatga agggaatcat
    11041 tcttgctggg ggcagcggaa cacgtctgta ccctttaaca aaggcaacat cgaaacaatt
    11101 gatgccgatt tatgacaaac caatgattta ttatccaatg tctactctga tgttggcggg
    11161 aatcaaagaa attctgatta tttcaacgcc acaagataca ccacgtttca aggaattatt
    11221 tggaaacgga aatgatttag gactgcagat cgaatatgca gtacaagaaa gtccagatgg
    11281 attggcacaa gcgtttatca ttggagaaga atttattgga gatgatagtg tctgcttggt
    11341 attaggggac aatatttact atggtggcgg tctgtctaaa atgttgcaac gagcagcttc
    11401 aaaagataca ggcgcgacag tatttggcta tcatgtcaat gatccagaac gctttggtgt
    11461 agtagaattt gatgagaata tgcaagcttt gtcgattgaa gaaaagcctg ctcagccaaa
    11521 atcaaattac gctgtaactg gcctttattt ttatgacaat gaggtaattt ctatcgctaa
    11581 aggtatcaaa ccttcagaac gtggagaact agagattacg gatgtcaata aagcatattt
    11641 ggataaagga aaactatccg tagaacttat gggacgcgga tttgcttggc ttgatacagg
    11701 aacacatgaa tcattgcttg aagcatctac ctttatcgaa acaattgaaa aacgtcagaa
    11761 cttaaaagtg gcttgtttgg aagaaattgc ttaccgtatg ggctacatcg ataaggaaca
    11821 attgctggcc cttgcacagc cattgaaaaa aaatcaatac ggtcaatatt tattgaattt
    11881 ggccgctgaa taaggagtcc ttacagatga aagtaacaga tacaaaatta acagatgtca
    11941 aaatcgtaga aatggacgtc tttggcgatc atcgcggttt cttcacagaa agttattcaa
    12001 aagcaaaatt tgcagaacat ggattgaaat atgactttgt tcaagacaac cattcactat
    12061 cagctgaagc tggtgtcctt cgggggcttc atttccaaaa aggagaagct gcacagacaa
    12121 aattgattcg ggtagtcact ggagcagttt tagatgtagt agtggatatc cgcaaaggta
    12181 gcccgactta tggtcaatgg gacggattta tcttatctga acataatcat cgacagttgc
    12241 ttgtacctaa aggatatgcc catggattcg ttactttgac accaaatgtg aacttccttt
    12301 ataagtgtga taattactat aatgcagaag cagatggggg catcgcattt gatgatccag
    12361 atttagcgat tgattggcca attgatccat caagagcgat tatgtcggaa aaagatcacc
    12421 gtcatccgac attaaaagaa tttgaagcag aaaatccatt tgtttacgga gaaatctaag
    12481 aattaaggag aaattttctt atgaaaaaca tcattgttac cggaggtgcc ggattcatcg
    12541 gctctaattt cgttcattac gtggtaaaca atcatccaga agtgcatgtc actgttttgg
    12601 ataaactgac ttatgcagga aacaaagaga acttggccgg acttcctagc gatcgcgtag
    12661 aattggtcgt aggagatgtt gcagatgcag aattagtgga ccgtctagta aaagaagcgg
    12721 acgcagttgt tcattacgcg gcagaatccc ataacgataa ttcattaaaa gatcctttcc
    12781 catttgtaca aacgaatatc attggtacgt atacactttt agaagcttgc cgcaagtatg
    12841 atgtacgcta tcatcacgta tctactgacg aggtttacgg cgatcttcca ttacgtgaag
    12901 acctgccagg acatggggaa ggcgaaggag aaaaattcac tgcggaaaca ccatataatc
    12961 cttcaagtcc atattcttct acaaaagctg gttcagatct gttagtaaaa gcatgggtgc
    13021 gttcttttgg cttacgtgca accatttcaa actgttcaaa caactatggt ccttatcagc
    13081 atattgaaaa atttattcct cgccaagtaa cgagtatctt aagcggtatt cgtccaaaat
    13141 tatatggcga aggaaagaat gttcgtgact ggatccatac gaatgatcat tcttcagcag
    13201 tgtggctgat tttgacgaaa ggcagaattg gcgaaaccta tctgatcggt gcagacggtg
    13261 aagaagataa taagaccgtg atggaattga tcttagaaat gatgggccaa ccaaaagacg
    13321 catacgacca tgtaaacgac cgcgcagggc acgatttgcg ttatgcaatc gattcgacaa
    13381 aattgcgaga agagctaggt tggcagcctg agtttacgaa cttccgtgat gggttggctg
    13441 acacgatcaa atggtacgaa gaacatgaag actggtggaa aaaagaaaaa gaggccgttg
    13501 aagcagcata tgccaaaaat ggacaataat acagaggaaa tttcactgta ttaatggaaa
    13561 aacacatgtg aggcaggcgc tcgcctgtct cttttttaaa ataaaaatca aggagcggat
    13621 aaccatatgt ttttattaac tggaggaaat ggacaattag gtacagaatt gcgccattta
    13681 ttagatgaaa aaaatctgcc atatgtttca acagatgcaa aagacttgga tatcacagat
    13741 gctgagaaaa caatggctta tattacagaa ttaaaacccg atgttatttt ccattgcgca
    13801 gcttacacag cagtagataa agcagaagaa gaagcaaaag aattagatga gaaaatcaat
    13861 gtcgatggca caagaaatgt agcacttgca gcaaaagctg tgaatgcaca attcgtctat
    13921 atcagtacag actatgtttt cgatggaaaa aacaaaaatg tagaatacga agtagacgac
    13981 caaacgaatc cactaaatga atatggtcgt acgaaattat taggcgaaaa agcagtagaa
    14041 gagattttag aagactatta tatcatacga acttcttggg ttttcgggat ctatggacac
    14101 aatttcgtct tcacgatgca acgcctagcg gaaacccgcg acaaactgac tgtagtaaat
    14161 gaccagtttg ggcgaccaac ttggacacgt actttggcag aatttatggt atatgtcatc
    14221 gaagaaaaag caccatttgg tatttatcat ttgtcgaacg aaaatagctg ttcttggtat
    14281 gagttcgcaa aagaaatatt gaaagataca gatgtagaag ttgcacctgt tacgtcagaa
    14341 gaatttccgc aaaaagcaac acgtccgcag tattcagtca tgagcctgaa aaagacagaa
    14401 gcgttaggtt ttgtcatacc aacttggcaa gaagcacttg cgcaaatgct ggaagctgcc
    14461 aaaaaaatga ataagtaatt tcctttttat caaatagaat ttggagcatg atatggaaaa
    14521 acaaacaaga agtgcacgac gaaaagaaaa gccaaaagcg aatcaggcag attcgaattt
    14581 ggtgcttgac ctgtttctaa aactccgcta tcttattggc gttttagtca tcgtggtcat
    14641 cgttactttt aatttaaacg gaagttcact tggtgtttgg gataaatatg tgtcgcaaag
    14701 agacgatggg aaaaaaactg atgtgatttt tggacagaat cgggaagtgc ggtcagacga
    14761 atggctggtg cagacacctt tttacctctc acaagctgaa gaggactttt cgttggtgaa
    14821 cgaggattat tcattaaacg gacaaaacat gatcattgcg tataattctc ctgtaaagga
    14881 tattacggtt atcggaaaac cattcaactg gggattcttt ttcctcggaa gagatcgagg
    14941 actttccttt tattgggcga tgaaattagt cgtcatggtc ttgcttggat tcgaagtact
    15001 gatgatatta acgaagagga aaaaagctct atcgctaatc ggtgcatttg cgctgacatt
    15061 ttctccagca gtccagtggt ggttcatgca acatgtgggc gatttgattt tctttacttt
    15121 gggactgatg attgcttttt atcattattt ctacaatcat gataaaaaat ggctacgaac
    15181 gttgatgatg cttttggtgg ttattttcgg tattgggttt attttagtga tttacccagc
    15241 ccatcaagtg atgctggcgt acttgctgat tttttatttt gttggcctgc ttatttacta
    15301 tagcaagaaa gtttcatggg atctgttgga tgtagtgttg attggagggg cagttttatt
    15361 tattggcgga gtcatggttc atttctggct aacgtcaaaa gacgcattgt tagcttcttt
    15421 gaatacctta tatccaggaa aacgggtaag tactggagga aagtggacga ttggcgaatt
    15481 tttttctttc cttacaaatt ggaaaattcc ttttgaagat atcaactatt cgaataactc
    15541 tgaagtggcc ctgttctatc acttttttcc aactgtattc ctagcaagtc catttgtgtt
    15601 atttggcaaa aaagatagcg aacaaaagtt actgggacgt attttgatga ttttttgtct
    15661 gttttctatc ttttggatta ccgttgggtt gccaaaatgg ctagcagaaa tcactctgct
    15721 gtcttatgtt cctccattaa gagccatcct tacttttagt tttgcggctt gtttattatc
    15781 gatctggttt atcgcttata tttggagaga agatgttatt cctatttggt ataaattcat
    15841 tttgttggca gtaaatgcat ggtcttattt ctatgcgatt acgcattcga aaatggataa
    15901 ttatttttcg gattttgaaa ccatcgcagt tgctgtgttg ggaacagtga ttttagcttt
    15961 tgcattattt ggctggagac gcttgtttta cctcgctttt gtcgccttag ttatcgtatc
    16021 tggctttttc gtcaatccag tcgtagaagg tacaggagcg atttttgaaa aaacactggc
    16081 aaaagaaatc caaaaaatcg atcaacaaga tcctggtaaa gtttggttgt ctgaagatga
    16141 attatataac ttcaccccaa cattgggagt gaaatccttc aatacagtac gcttttatcc
    16201 agatatagct gcatggaaga aaatcgatcc gaaagaagaa tacgagaagt attataatcg
    16261 gtatgctcat acaagagctt ttatcgctaa ggaagataca aagttcattt tagatcgtcc
    16321 agatatgttt tcggtcacgt tgaattttga agacgcagaa aaattaggga tcgactatgt
    16381 gatcagtaaa cgaccattaa ctgattacaa ccaattatat gaagcgcagt tcacgcagct
    16441 atatggaccg gataaagacg gttatatgat ttttaaagta gaatatccgg attatccaga
    16501 tgtaccacaa acacaaactc aggaaaatca gctagtcgta cagtaatagg ctagctgaga
    16561 ataatcctga aatattagta gaaaggagag tgaagataat tcaagcaatc gtacaaaaat
    16621 ttgtcaacaa aatgagtgtc ggtttcttgc ttttgttgct gacgctagtc ttttttgttt
    16681 ggacagcagg ggtaggtttt ccagcaactt tgtttatata taacaatagt tcattactta
    16741 tcgcttttag tgtggctatt ttgctcattt taaatgttta taaagcaaaa ggcgtcgatt
    16801 ttctttatct aggtgttgcg cttgcccttt tcattttctt ttcttacttt cgggaattaa
    16861 gaaatgagtc tttatttgga gacttactgt ttcctttgat tattttattt tgtttagtaa
    16921 ttaaatggat cgagtggaca aaatgggatc gcggtattta tctgattgtc tttacggtct
    16981 tcctcggaat cacgttatat cgtgtattta cagagatcca agtaccagaa ggacaaagca
    17041 tctgggctcc aggcaattcg ctttctgata tttggatcaa tacgaataca atcggaagtt
    17101 ctttgatgac tcttgcttta ttgatcagtg gatttgccag ttcttttgaa cgatggtatg
    17161 ttcgaatcat cggtgggata gcagtcgttg cagccttttt aggtatttgg gtctgccaat
    17221 ctagaggtgc attagtcgcg ttgattgttt ttgcgatatt ggatctttta cctaaatcgt
    17281 tgatgcgtgt cattcgtgcg ccatttattg cctacacggt tacgattctt ttagctttgc
    17341 cgatttctta tctggcggct gtctctgaaa aagtcaattt gtttaccggt cgagaagata
    17401 tttggcataa attctatcag acgctaggag aaaaatctga acaagtttta ctaggaatga
    17461 aaacatttat cttccagcga ggaaaccaat ttttaggaaa ccacaatagt tataattcta
    17521 ttttgaatat ctatggattg ataggatttg ggattgctgc tttgctgctt atccttttta
    17581 ttggtcgctt aacgttgaaa gcagatttat ccaacgggca gatgactttt atctgggcct
    17641 tttttgcggt gatgatgcag tcatttatgg aggatacatt gacttcatac ccatgggttc
    17701 cgattattta tatcctgttg gctatggccg ttcatcgata tgatgaacca gaagttacgg
    17761 aggaattcta tgttatggaa gaggcatatg acgatatgac ttatgatgat acatcttatg
    17821 aggaacaacc agatagcgct cattcttcca ggatccaacg ctatcattga taggcacaaa
    17881 atacgagaga ggctgtgaca accgtcgcag ccttttttgg tttattgcaa ttgtctagca
    17941 tcttctgtaa aatagaaacg ttagagaaaa tcttgtatca tagaaaatta agaaagaaat
    18001 aagaacgcag ctcggtacca aaaatatggt aaaatggcac ttgactgtaa ttcactgaaa
    18061 atcgcttgga ggaacacaaa tgtttaaaga tttgtattta tttatgaagg acatttatca
    18121 gaacagaaaa ttactgctac agttttcgat caatgacttc aaatcaagat atgcaggatc
    18181 gtttttagga atcttatggg cgtttatcaa tccgctattt actgtattga tttattggct
    18241 ggtatttggt gttggactga aagcacaaat gatcgatgca aaatacccat ttatcgtata
    18301 tttagttacc gggatgattc cctggttctt cttctcagat gcatttgcat caactacggt
    18361 tgtttttcgg gaatatactt atttagtaaa gaaagtcgta ttcaatattc gtatcttgcc
    18421 cacgacgaaa atcctatcca atctgtacac ccatttattc ttcattctga ttggcatagc
    18481 tgtcgcgctt ataaatggta tatatccttc agcaatgtct ttacagctga tttattattt
    18541 attttgcatg tgtgctttct tgacaggatt gacttggctg acggcatcga tccaaccatt
    18601 tttacctgat atcatgcaat taattacgat cgtgctgcag ttgatcatgt ggacattacc
    18661 gatattatgg agccctaatc agtttgattc aggtcttgta agcatattga aattaaatcc
    18721 gctgtactat gttgttcaag gttatcgtga gtcattttta agtgaagctt ggttctggga
    18781 gcatggaaca tatactttgt atttctgggt tttcacgtta gtaatgttcg taatcggctc
    18841 tgcagtgttc cgtagattga aaccacattt ttcagatgtg ctgtaaggag aatagctatg
    18901 acagaatatg caattagact aaaagatatc acaaaatctt ataatatgta cgcaaaacct
    18961 tcggatcgat ttcgtgaagc cctcaatcct tttaagaaat cctatcatga tgtattttat
    19021 gcgttgaaaa acgtgaatgt agaaataaaa aaaggtgaga tgatcggttt cgtgggagaa
    19081 aacggatcgg gaaaatctac aatgttgaaa atcattacgg gagtactgac accaacatcc
    19141 ggcacgatgg aaatcgaagg aaaaatctca gctttgctag aactaggatc aggattcaat
    19201 cctgagtatt ctggctatga aaatatctat ttaaatggaa tggttctagg attttcaaga
    19261 gaagaagtcg atgaaatggt cgatgatatc attgaatttg ctgacatcgg cgaccatatt
    19321 tatcaacctg taaaaaccta ttcaagtggg atgttcgttc gtctagcttt tgctgtagcg
    19381 atcaatgtga atcctgatat tttgattgtg gatgaagcat tggcagtagg agatcttgaa
    19441 tttcaactaa aatgtatgga aaaatttaca gaaatcaaga actcgggaaa gacgatttta
    19501 ttcgtttctc atgatattag ttcgattcgc cgtttttgtg atcgttccta ttggttgaaa
    19561 aatggaaaag ttgtcgaata tggtgatacg atggaagtaa cgacgaatta cgaaaacttt
    19621 ttgaagaaaa aatcagttaa aacagtagat cgaaataaaa accaagtaga acgcttcgca
    19681 gctccagata tcgtagacgt gacgaaagcc gaattgttgg ataaagataa aaatccagtg
    19741 gatatgctgg aacaaggaga aaaactatac gttaaagtaa cctatgaagt aaaagacgat
    19801 acaatcaaaa atccagtttt aggaattgct ctgcgtacag tcgacaattt ttatgtgtgc
    19861 ggactcaata ctctactaga tggtatcaag atcccttgga aaaaaggtga gaatatcttt
    19921 tatctggagt atgaaaagtt aggtttgtta gctggtgaat attattttga cgttgcggtc
    19981 tttgaagaaa atgcaacggt tcctttggta tacaagacaa aatacatgaa cttgtttgtc
    20041 agcggttctt atatcggaga aggcatcgtg gtcttagacc ataaatggga agaagggact
    20101 catagcaatg aaatatgatt ttgaaatgga cctagatgaa caaagcagtg tgggaaaaat
    20161 tgccgcacag atcaaaccag gaagtaaagt tttagagttt ggtcctggaa acggccgatt
    20221 aacgaaacat ttgatcggag caaaacaatg tgaagtgagc attgtcgagc tagataagga
    20281 attgttcgat tttgtcagcg agtttgccca agatggattt tatggagata tcgaaagttt
    20341 tgaatgggca aactattatg ctggacaaac atttgattac gttttgtttg ccgatgtttt
    20401 agaacatttg gtagatcctg gaaaaacgtt gaagaaagtt agagaatttt tgaatgaaga
    20461 aggagaaatt ctaattacat tccctaacct tgcgcataat tctgtcatga ttgatttgtt
    20521 caataatcaa ttgccatggg cttcttatgg tttgctagat gaaacccata attcttttta
    20581 tactcatgat ggcttccaaa aagtttttga aaaagcagga ttatacatca atattgaaga
    20641 ttatttgtac ttagctgtag gtgatacaga attaaaatca acttatgaag aattgccgga
    20701 agctgtacgt tatgatttca aaatgcgacc atttggcgaa gtctaccaat acttcttctc
    20761 attgatgaaa catccagtag cacaaagttc cattgcgcag ccgcaaaatt ctaattatgt
    20821 gaaagtatta gaagtaatcc agcaaacgaa acaagatgaa ataattcaac aaataccatt
    20881 caataatttc acaggggaaa atgagacact aagtttccat gtatcagaat tagcagaacg
    20941 aatggtgttt cgcttcgcgc agcaacctag ctttatcgaa ttcagcgcag aagctgctgg
    21001 agaaaaactc acatttatcg attcaaatgc tgtagtcaaa acagtaaatg attgttattt
    21061 gtttgatggt aaagatttac cagagttctt tttaacggat attgcaggga aagaagtgac
    21121 tatccattgt cactatcgtt ttatcggaga attgacacca acaatgaaag aattgctgga
    21181 aacaatccgt ccaatggctg aagttacaaa gcagctttct gagaaaaatg atgaattaga
    21241 aagagaaaat cattatctta ttgagaataa tacaagatta gatcagacgt tgaaaacaac
    21301 cataaatcgc tattgcacgt tgttggaaag tgatgaatgg acaatcaaac atagattagg
    21361 gcgacgtaag aaagaaacat cgaaaaaaat ccaagaaaaa gagctttctc tatgtattga
    21421 cgaaaaaatc tgggatgcag aaacaaagat attgaaaatc atcgggtggg gaatcgctaa
    21481 ttcggatcgc caaccattgt cctataagtt atcagccgac caatcaccat tttttgaagc
    21541 aattcctgtt ttacgagaag aagtcaatca agcaaaacag ctagctgaag gagcaaaagc
    21601 aggatttgaa ctgcggatcc tttgcgagaa ggaacgttca ttcttagttg aagcagtggc
    21661 tcaaaatggt caatcatgga tcattgaaat gtaaataatg attaacttat aaagataagg
    21721 agtaaacgaa tcgtgcaaaa aaaagaaatt gccgtattta tcgatcaaat cactcgtgaa
    21781 cgggccactg gcgatttgct tattgtgggc tgggcaattg atgaagtgac caaagaaatc
    21841 cctacgataa aggtagaaaa agaaaatgtg attgctgaag caacacatgt cgtaagattg
    21901 gatatcaatc atttatataa tcttgatgtt aagacccaaa gcggttttaa ggtacgttta
    21961 tcagggaaaa tgagaggaaa agcaatctta gacttccaaa cagcaagaca tcaaaatggc
    22021 atagctgtga aattaaacgg taaatatcct tatgatgacg gcattgaatc ttcatgggaa
    22081 agaaaaaaaa gattactgaa aaaagggata aattatgcaa ggactcatgg cgtaaaaaaa
    22141 gcaatccgcc gggtcaaact ggaattgaaa ccaggatcga tcgactatgc agagtggatc
    22201 agtcgtcatg agaaacctga tctgaaagag caaaggaaag aagtacaagg atttgcctac
    22261 cgcccattga tttccatact tatgcctgtc tataacgttg aaatcaaatg gctcgaaaaa
    22321 tgcattgatt cggtacttga tcaaacgtat gatcactggg aactatgtat cagtgatgat
    22381 gcttctactg atccagctat ccgaaagtgt ctagaatcct atcaagcaaa agatgataga
    22441 attaaagtcg ttttccgaca agaaaatgga cacatcagtc tggcaactaa ttctgcattg
    22501 aaaatggcag aaggagagtt tatagcgctc ttagataatg atgacgaatt acctccattt
    22561 gccttatatg aagtggcaaa agtgctaaac gtacatccag aactggattt gatctacagt
    22621 gacgaagata aaatcgatgc agatgggaat cgctttgacc cgcacttcaa agcagactgg
    22681 tctcccgata cattgatggg aaataattat atctctcact taggcgtata tcggacaagc
    22741 attgttaagg aacttggcgg tttccgtaaa ggatatgaag gctctcaaga ttatgatttg
    22801 gttcttcgtg tgacagaaca aattcctgca gaacacattt accacattga ccgtgtcttg
    22861 tatcattggc ggacgatccc gggatcaact gcaagcaatg gagaagctaa aagctacatc
    22921 tatgattctg gagtgaaagc attgacagat gctctatcta gaagaaatat caagggaagc
    22981 gtacatcctg gcagaatttc tggtttttat gaaatcactt atgatgtttt gcaagaagac
    23041 ttggtcagtg tgatcattcc aactaagaat ggctatgaag atctaaaaac ttgtgtggat
    23101 tcgatcatcg aaaaaacgtc ttatccaaat tatgaaatca ttattgcaga taatggaagt
    23161 acagatccta aaatgcaaga attatttgca gaatacaagc atcagctgaa agaccgattt
    23221 atcgtcgaat taattgacat tccattcaat tattcacgta tcaacaatct ggcagcagaa
    23281 aaagcaaacg gcaaatactt tttattcttg aataacgata cagaagtgat tgaacctgac
    23341 tggatgacag cgatggtttc ttatgcacag tttgatcgaa tcggctgtgt aggagcaaaa
    23401 ttattttatc cggatgatac aacgcagcat gcaggtgtat tattagggat cggtggcgtt
    23461 gcaggacatg cattgaataa ctatgatcga acacattgtg gttactttgg ccgattggtc
    23521 attgacgtca attacttagc agtcactgca gcttgtatga tggtcaaggc agctgacttc
    23581 aatgctgtca atggatttga tgaaatatta gaagtagcat tcaacgatgt tgacttgtgc
    23641 ttgaaagttt atgaactggg tcgttacaat gtctatgcac atcaagcaga attgtaccat
    23701 ttcgaatcta aatcaagagg ttatgaagat acaccagaaa aacaaagacg ttttgctggg
    23761 gaaatcaaaa aaatgcaaga taagtggcct tcttatattg ctcatgaccc attttataac
    23821 gataatctaa ctaaagaagg aatcggcgat ttttcgttga gacctgattg attaaaagaa
    23881 ctgtattttc atttttatta atgaaaatac agttctttta atttaattat atgatttgtc
    23941 aaattaagct agaataaaat gcttcttgta catagctcaa aaatatttcg attggtgttc
    24001 tgtaattcaa tgattttctt ggaatatgat tacgttgatt gctgacactg gaaataaatg
    24061 tctgattcac tt
//
LOCUS       DAXQKX010000038        23816 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.038, whole genome shotgun sequence.
ACCESSION   DAXQKX010000038 DAXQKX010000000
VERSION     DAXQKX010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23816
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.038"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(45..779)
                     /locus_tag="ACF3MF_001731"
     CDS             complement(45..779)
                     /locus_tag="ACF3MF_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HFE3927718.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1106..1516
                     /locus_tag="ACF3MF_001732"
     CDS             1106..1516
                     /locus_tag="ACF3MF_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HFE3927719.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1509..2210
                     /locus_tag="ACF3MF_001733"
     CDS             1509..2210
                     /locus_tag="ACF3MF_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HFE3927720.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2210..3796
                     /locus_tag="ACF3MF_001734"
     CDS             2210..3796
                     /locus_tag="ACF3MF_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3927721.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3815..4036
                     /locus_tag="ACF3MF_001735"
     CDS             3815..4036
                     /locus_tag="ACF3MF_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HFE3927722.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4033..4793
                     /locus_tag="ACF3MF_001736"
                     /pseudo
     CDS             4033..4793
                     /locus_tag="ACF3MF_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
     gene            5173..5682
                     /locus_tag="ACF3MF_001737"
     CDS             5173..5682
                     /locus_tag="ACF3MF_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HFE3927723.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5757..6296)
                     /locus_tag="ACF3MF_001738"
     CDS             complement(5757..6296)
                     /locus_tag="ACF3MF_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HFE3927724.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6436..7047)
                     /gene="rpsD"
                     /locus_tag="ACF3MF_001739"
     CDS             complement(6436..7047)
                     /gene="rpsD"
                     /locus_tag="ACF3MF_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HFE3927725.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7309..8160
                     /locus_tag="ACF3MF_001740"
     CDS             7309..8160
                     /locus_tag="ACF3MF_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HFE3927726.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8188..8823
                     /locus_tag="ACF3MF_001741"
     CDS             8188..8823
                     /locus_tag="ACF3MF_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HFE3927727.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8843..9616
                     /locus_tag="ACF3MF_001742"
     CDS             8843..9616
                     /locus_tag="ACF3MF_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFE3927728.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10024..10821
                     /locus_tag="ACF3MF_001743"
     CDS             10024..10821
                     /locus_tag="ACF3MF_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HFE3927729.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10799..11212
                     /locus_tag="ACF3MF_001744"
     CDS             10799..11212
                     /locus_tag="ACF3MF_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFE3927730.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11196..13841
                     /gene="mutS"
                     /locus_tag="ACF3MF_001745"
     CDS             11196..13841
                     /gene="mutS"
                     /locus_tag="ACF3MF_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFE3927731.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13859..15967
                     /gene="mutL"
                     /locus_tag="ACF3MF_001746"
     CDS             13859..15967
                     /gene="mutL"
                     /locus_tag="ACF3MF_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HFE3927732.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15989..16549
                     /locus_tag="ACF3MF_001747"
     CDS             15989..16549
                     /locus_tag="ACF3MF_001747"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphatase"
                     /protein_id="HFE3927733.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16634..18622)
                     /gene="treP"
                     /locus_tag="ACF3MF_001748"
     CDS             complement(16634..18622)
                     /gene="treP"
                     /locus_tag="ACF3MF_001748"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HFE3927734.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18845..19558
                     /gene="treR"
                     /locus_tag="ACF3MF_001749"
     CDS             18845..19558
                     /gene="treR"
                     /locus_tag="ACF3MF_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HFE3927735.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19635..20081
                     /gene="msrB"
                     /locus_tag="ACF3MF_001750"
     CDS             19635..20081
                     /gene="msrB"
                     /locus_tag="ACF3MF_001750"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HFE3927736.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20251..20853
                     /gene="ruvA"
                     /locus_tag="ACF3MF_001751"
     CDS             20251..20853
                     /gene="ruvA"
                     /locus_tag="ACF3MF_001751"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HFE3927737.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20866..21867
                     /gene="ruvB"
                     /locus_tag="ACF3MF_001752"
     CDS             20866..21867
                     /gene="ruvB"
                     /locus_tag="ACF3MF_001752"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HFE3927738.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21896..22474
                     /locus_tag="ACF3MF_001753"
     CDS             21896..22474
                     /locus_tag="ACF3MF_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFE3927739.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22526..23008
                     /locus_tag="ACF3MF_001754"
     CDS             22526..23008
                     /locus_tag="ACF3MF_001754"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HFE3927740.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23125..23499
                     /locus_tag="ACF3MF_001755"
     CDS             23125..23499
                     /locus_tag="ACF3MF_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927741.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7774 a         4284 c         5114 g         6644 t
ORIGIN      
        1 ttggtacgca atcgctgtac caagtttttt tatttagctt ttgattaagc cataaataat
       61 aatttatata agaatactgc tacgacacca gcacagatag gtgctacaac tggtacccat
      121 gcatatcccc attgagaaga acctttatgt ttcaatggaa gaagtgcgtg tacaagacgt
      181 ggagcaaagt cgcgggctgg gtttagtcca ggacctgtag gaccaccaag tgaagcaact
      241 aatgtccata caaggaaacc aagtgctaag tgagctgtac caagattatc ttggaagaat
      301 ggtgcttttg taatacctag ggcaccaaag aataaaacga atgaaccaaa gaattcattg
      361 acgaaaccat tgaatttaga accaacgctg ttgattgttg agaatgtacc taacacatgg
      421 tttacgtctt ctgtttggtc gtagtaaggt ttgtaacaag ctactacgat caattgtcca
      481 atcgctgcac caatcaattg tgcaatgata taaggaacaa cttcagccca agggaataga
      541 ccattagatg ctaaagcaat tgtaaatgct gggttgatgt ggttaccgct gattccacca
      601 aaaatcattg ctggcatcat aaccccgaat ccatacccga cagcaatcag catccagtca
      661 ctgccatatc cttttgtacc ttttaaatct acgtttgcta cagcaccgtt acctagaacg
      721 attagtaatg ctgtaccaat catttccgcc gcaagacggg tcattagtga gtaatccata
      781 aatacctcca aaagttataa aaatgcaaaa aaaaaagaaa catcaacacg aaaagcatcg
      841 gtgcagtgtt tcgtgtcgga aggatttctg cagtcttaac aaatgtgaat aaaaaaatga
      901 attccattac ttataagaaa ccagaccaac agtaaaactc caactctttt taaaagttct
      961 ccacaaatca ccaagcttaa ctataaatat accaaaaaaa aaacgttttt tttctcaaaa
     1021 attgtatctt agaaacagca tgttttgaaa ctttcagaaa aggtttgtta gtaaaatgaa
     1081 agctatacgt aaggagtgtt gtttgatgaa attttttcaa gagtttttca ttattatttt
     1141 cttttctgta ttaggagaag gcatacggat ttttgctcat ttacctattc ctggaagtat
     1201 cttaggtatt ctttttttat ttttagcatt tgaaatgcat cttgttgatc ctgaaaaaat
     1261 cggagcaact ggtgattttt tattgaataa tctagccatt ttatttgttc ctgctggtgt
     1321 aggtttattg gaatattttg atgatattgc ttcgatatgg cctgttttac tgggagcagt
     1381 cgtcgtgtgt tccatcgtca cgatggttgc agcgggaaaa acggcagaag gtgtagaagc
     1441 tttgctgggc tatgtccgta agaaaaaagc agaaagggta tctgtaaacg aaatggagga
     1501 gaatcaaatt gactgagttt tttgtgaatc cattatttgg cttaagtttg actttaggag
     1561 tgtacgtatt atctgacaaa tttttgcgga aatataaact gcctgttttg aatcctctcg
     1621 tattatcgat tgttgttatt atcttatttt tgcatttttc tgggatcagc tataaagact
     1681 ataatatcgg gggcaatttt ttgactatgc tgattactcc tgcgacagtg gcacttgcca
     1741 tccctcttta taaaaacttc cgtttactga aagagaattt ttatcctgta atggctgcga
     1801 ttttagcagg aatagtcgca aattgcttgg ttagtgtagg gttcggttac ttcttctctc
     1861 ttcataaaga gatggtgatc tcattactac ctaaatctgt aacgacggct atttctgtcg
     1921 atttatctca tacgatgggc ggggtgaatg ccgtgacact tgctattgtt gtctctacag
     1981 gtatttttgg ttcgctgatc gccactcata ttttccgcct attcaagatc gaaagtccag
     2041 ttgctcgcgg tgtggcgtta ggaagtactt ctcatgctat tggtacagca aaagcaatcg
     2101 agattggtga aatagaagga atcatttccg gacttgcgat atgcgtcaac ggaatattga
     2161 ccgttttatt gctaccgtta ttctttcagc cttttgctgg cttgttttga tgcgaaaacc
     2221 actattttat gctacaataa ccaaaacgtt cgagcataaa aaaggaggga aagacgtgta
     2281 tttgtcttcc gagtatctta aacaatttga taaagatcta tattataaga ttctcctcct
     2341 agaaagtttt gaggatcaag cttggcatac cgctgcacaa ttagcgcaag ttgttcagct
     2401 ggatgcccgc agcgtgtcga aatacctgaa cgagctgtct aaaaactatc agcagtttag
     2461 cggtaagaca caccctttgt ttacaaaaaa tcaccgttct ggttataact tttatgatac
     2521 gctcgattca attgaacatg agcgtttttt gatctatctc gtgcaaagta cgctgaaatt
     2581 ccagttgctg cacgacattt tttttgaaga attccataca atgtaccaat ttgcgcaaaa
     2641 gcattacatt agtgaatcta ctgctcatcg aaaaatcaat gaatggaaac agcaactgca
     2701 aacttacgga attcggctgc aacgaggtac atatatcgct caaggcgaag aagaaatcat
     2761 tcgactttac ttgcatatga cattctggca gttgtttcga gggaaaatct ggccatttga
     2821 aacgatttct caaatggacg taaagaatat ggcagaacat atcatggctt tttttaatgt
     2881 tcgtctgaac gagatcaaaa aaagacgatt ggaatatatg ctaggtgcct tttttttaag
     2941 aaaatcacag aagcattatg ttgtattgaa tgagaaaaaa agacggctga tttctgacaa
     3001 tctgttgttc cagcgatttt gccaggtcat ggagccggta tttcctaatt attttcaagt
     3061 agaagacgag ttaggcgcat tatttcttgt actgatgact cgtgaagaat attatagtga
     3121 tcctaagata cggaagaaaa tttttgattt tcatcaacaa gcaaaaacac cgccctttac
     3181 agccctttca gaagcaaaag ccgctctttc tctttatcag gaagagcagg ggctgccagc
     3241 agaaaatcta accttcgagg cagaaaacta tttattcagc agtcattttt tcgcctatct
     3301 ttttcctaat gcgaaagaaa cgattgatgg caatagtagt gattttatta atcatttagt
     3361 tattgaaaac aaggaattga aacaatggct cgtacatttt tttgaaagta gacacaaaca
     3421 tcccaatcat ctggcattta aaaatcatgc gtttttgatg gggcggtatc tgactgtgtt
     3481 taaaacatta ggagccttta ctccacagct tccaaagatc acgatccttt taatgacaga
     3541 tttcccatta tttgaagagc aactgttaga ggagggatta cggacatttt tccgtaatga
     3601 gtatcagctg atttttctgc caacagatta tcgggggaga gaagttgatc ttctgatttc
     3661 gacaagtaaa gtccaccgca aaccatgggc ggatcttgac tattttattg tgactgaaga
     3721 actaaaatta attgattaca tccaactatc tcaaaaattt gaaatgattc aaaaacaaaa
     3781 actattaaaa caataacaaa gaaggagaaa aaagatgaca tttgaagaaa ttttaccaga
     3841 attgaaaaaa ggtgcaaaga ttattcgtaa aggatggagt ggatttgaac tttatgttgt
     3901 tctcgtatcc gatgatgaat ttgatggctg tccggtgacg ccgtacttat tgatcaaaac
     3961 aagtgacgaa ggtttttcca gcttcgctcc tacagtttgt gatattttag cagatgattg
     4021 ggcgatcgta gaatgaaaaa ccagtatcca gatctagcta aacaggttgt atttatcaca
     4081 ggagctgctt ctggaattgg tgctgcgcaa gcccgagcgt ttcttgaaca agatgctttt
     4141 gtatttggat tagatcaaaa gttcggtaaa atggaagaaa tttctttgcg atttcctgaa
     4201 acttttgcct acgcactagg tgatgttcga caaatgaaag aactccaaca agcggtatcg
     4261 aaatgccaaa atcattttgg tgaagttacg attttactga atacagcggg gatattggat
     4321 gcctacaaac ccttgatgga aactgacgaa tcgctgtggg atctgattta tgagacgaat
     4381 gtgaaaagca tgtatcagct gacaaaaatc atccttcctg atatgatccg ccaaaaagcg
     4441 gaacgatcat caatatggct tcgattgctg gcttgattgc tggtggaggt gggatcgctt
     4501 atacaagcgc gaaacatgcg attgtcggat ttaccaaaca actcgctctg gattacgcag
     4561 gacagggtat ccgagtaaaa ggaattgctc caggagccat ccaaacacca atgaatgcgg
     4621 ctgattttga agggaaaggt gagatggcag agtgggtggc aaatgaaaca ccagtcaagc
     4681 gatgggcaca gccggaagaa gtagctgagc tgacgttatt tcttgcctct cctcaagcaa
     4741 gctacataca aggaacgatc atcccaatcg acggcggatg gttgttaaaa taaccttgtg
     4801 tttttttcaa gcttctgtat gataaaacta aagagagaaa caacggttga tgataaaaaa
     4861 agtcgatgac tgttcccgac attcgatgcc gaacagccag ttcaaaaaat tctttttaat
     4921 aatcgttaat attcgaaact aagcggcttt tcacgacctc ttgatataaa cgatattcaa
     4981 aagcttgcaa ctgcggtaac aagtccagcc aaatgaaaaa tataaggagc tatttttatt
     5041 tgaccattct tattacttgt tgcagggcag ctttttcact accttctgcg acacttcagt
     5101 tggaattttc ttcccatcct ttggtcgcgg tcattaccaa gataaaatta tcttgcaaag
     5161 gagaaataga acatggaaaa aaataatacc cgttcagcca aacgctggac aacgacagat
     5221 gtgactcgga tggcgctagt cactggttta tatgtggcag tgacgctggt tttgtctgtc
     5281 tttagctttg gagtgattca gattcgtctc tcggagatgt tcaactatct gtccttgtat
     5341 aacaaaagat acatcgtcgc ggtaacagcg ggagtagctt tggctaatat tgcttctcct
     5401 cttggactga tagatgttgc agtaggaagc gtcagcacgc tgcttgtatt gcttatcaac
     5461 tataaaatca ctagtcgcat caaaaacatg aaaatcaaaa tggccgtgac agcatgcgta
     5521 tttgcttttt ccatgtttac agtagctggt cagctaacga ttttatatca actacctttt
     5581 ttcttgaatt ggtgggtgat tgctttagga gaattggcat caatgattgt cggtgggata
     5641 attatttatt ggatcggtaa aaaagtggat ttgtcaaaat aaagatctgt ttaatttaaa
     5701 atagggcagc atggaagaga ctgaatgttg agtcttcttc catgctgctt ttttgattaa
     5761 tttgtatgaa gaaatcgatt tagccgtttt ttcatcaaga taccgatata agctgctcca
     5821 gttgccttga ttgcttccgg cagtaaaaac ggcagtagtc cactggcaaa tgcagttgta
     5881 aaagtaagat caccacttat tttcagccag atcgttccgc agatcaatgc agcaagagag
     5941 cccattagat tggcaaagat tgcatataag taatgagcat ccgttctttc gatcatccaa
     6001 ccagttatcc acgtttgtaa gagaaatcca atcaaatatc cgccagttgg cccaaataaa
     6061 acagctatac ctccagtcat ccctgaaaat acaggaagac caatcaagcc aagtaaaaga
     6121 taaactccaa cagatatcaa tcctagtttt cttccgagaa aagttgctgt taatccaata
     6181 gcaaatgttt gccctgtcaa aggaaccaaa ccaaaaggaa tggtcatctg agaaaggaca
     6241 gaaataatcg cggcaaattc cgcagcaagt atcaattctt tcaatgttcg gttcataacg
     6301 ccctcttttc gttaacttaa tatttttatt tggttaacga aattgtaaaa caaagtgatt
     6361 actttgtaaa tagaaaatat aaaaaaagac cagctatcca atagatagcg gtctttttca
     6421 agaaagcttt tgaaattata agctttggtt gtagtattca acgacaagag cttcgtcgat
     6481 ttctggatat agttcgtcac gttctggtaa acgagtcaat gaaccttcca atttttcagc
     6541 gtcaaagctt acgaatgctg ggcgtccaac agttgcttct acagcttctt ttactgttac
     6601 gatgttttgt gatttttcac gaactgagat cacttgaccc acttctacgt ggtatgaagg
     6661 gatatcaacg cgtttgccat caactaaaat gtgaccatgg ttaactaatt gacgtgcttg
     6721 acgacgagtc gttgcaagtc ctaaacggta aacaacattg tctaaacgtt gttctagtaa
     6781 gatcatgaag ttaacaccat gtttaccttc tttgattttg ctagctttta cgaacaagtt
     6841 acggaattga cgttcgttca ttccgtacat gtgacgaagt ttttgttttt cagttaattg
     6901 catgccgtat tctgattgtt tgccacggct attaggtcca tgttgacctg gtgcgtaagg
     6961 gcgacgtgct aattcttttc ctgtgcctga caatgagatg cctaagcgac gagaaatttt
     7021 ccatgatggt cctgtataac gagacattaa aatttcctcc aatgaatata agtttttgga
     7081 gtaaaataat ccgttgaaaa attcataatc atatagtttg ttcttcaatc ttcacctttg
     7141 cagccgcggt tacacaatcg aacccgagac ggggcaacaa actagggatg agttattatt
     7201 tttctgctgc attattttac acaaattaca gtatatgata gatcatccac gaatgtcaag
     7261 ataattagta cataaaaacg ctttacaaac ctaggctgtc tttataaaat gagagggtat
     7321 gtgcaaatgg aaaaaagcga aggaagttta aggagaaaat caatgaatcc ggtatcacca
     7381 ttatttgaga aaatcgatgc ttcaattgaa aagaaggcga atctttttga aaacagcttt
     7441 tcacgttacg ctgttcgagc ggttctcgcc tgtttgtttt tgactttagg aacggctgtg
     7501 gcatttgcga tcgcgatgaa gggggaagat atcgcgcatg gtctaggaaa gattttatac
     7561 gcatttatgt tcagctgggg tctggtcatg attctataca tgaacgccga attaggaaca
     7621 tcgaatatgc tttatatgac cgtgggtgtt tttcggcaga gacttgcttt aagtaaggca
     7681 gccaagattc tatttgcctg tatttttttc aatatgattg gcggtatatt atgtggattt
     7741 ctaatttcta tgactacgcc atttcaagat ttaacgttgg acaactttat gttagaatca
     7801 atagcagtaa aactagcaaa accttcagca acgattttgg tggaagggat gtttgcgaat
     7861 atcgttgtca ataccgctgt actgatcagc atgcggatga aagaggatgt cggaaaagtg
     7921 atcacagtcg tattcatcat tttcattttt gcttttttag gatatgaaca cgtgatagcg
     7981 aattttcctg cctttacgct tacttacttt gcttctcacg gacagatgga tggaatgaca
     8041 gtcagcaatg tgttacataa tttgtttttt gctttggcag gaaattatat tggtggcggt
     8101 ttagtaatgg gactgggata tgcttggctg aatcagtcaa aatcatccta tgtggactaa
     8161 aaagtcgttc attaaagggg aagtgccatg gaagttttag tttttccaaa aaatgaggaa
     8221 aaagcgttac aaatggaaaa gtacatgaaa aatctttttt cctttgctgg agtacctaag
     8281 ccggaacgcg ctcttttaca acaaccgtta ctggatgaga gcaaaaattt atctatttct
     8341 gaagttttag cttttgttca ttattattat gaacaaatcg aaagagagta tcagtatgta
     8401 gcgatcgatt tagtccagaa aaacatcaaa cggcttacat ttgaagactt agtcgtattg
     8461 ttgccactag ttcagaaaaa agaatggtgg gacagcatcg actcttggag aaaagtatac
     8521 agcacatggt gtaaagccta cccagagcag cgtgaagaag tctttcaatt gtttgaaaaa
     8581 aaggaagatt tttggctacg tcgaatagca atcacgttgc aattaggtta taaacagcaa
     8641 acagacacag gactattgat ccgagcaata gacgaagatc gtcaaacaaa ggaattcttt
     8701 atccaaaaag caattggttg ggcattacgc gattatagta agaccgatgc cgattgggta
     8761 aaaagacagc tgacaacaga tttgagtaag ttagctgttc gagaggcaag taagtattta
     8821 taagaaagcg agacgacaag agatgagacg caaattattt gcttttgata ttgatggaac
     8881 gttgttagat tcaaacaaac aagctttaga tagcacaaga gaagcattgg aaaaattacg
     8941 caaagccggt catctggtca cgattgctac agggcggagc cgatttcatg cgcaagagat
     9001 cattcgcgat cttgatttta cgaactacat tttatgtaat ggagcggccg gttttttaga
     9061 ccatgaacaa gtatataaga atttactaga tcgcgaccag ttggatgcgt tcgttcaaga
     9121 agcgcatcat gagcagatcg atacagcttt tgtcagctta gacaatatca agcgttcttc
     9181 ttccaatgat gtaacggtga tggaagaagc gatgcattct ttcggtgctg tcttgcctga
     9241 attagatcag ttttttgcag aggaacaaga aatataccaa gcgttagcat ttttcgatca
     9301 aacatatgat gggaagttct cttcatatga taaaattcga tttgtccgct ggcatgagaa
     9361 cagtgtagat gtcgtaccta aaaatggttc taaagcagcg acaattctgc acttagcaga
     9421 acaagtaggc atccctcatg aagacatcat cagctttggc gatggacaaa acgaccgtga
     9481 aatgttgcgc atgtcaggaa ttgggatagc tatggggaat gctgtgccag aagtacaagc
     9541 agaagctaag atggtcactg atacaaacga tcaggatgga atttggaagg cattgaaaga
     9601 gttaagcgtg atttaaaaga ggttgtgaaa aagctgttct gcatcaagta ataagcccag
     9661 ccaaacaaaa atagctcctc ctatttttcg tttttctggg cttattaccg cagatgcaag
     9721 ctttcgaaca ccgtttaagg aagaggtcgt gacagaagtg gtcagtttca agaaataaga
     9781 agggatttac gaaaattgct tctcaaattt ttgtaaaatt acggcttatt tctgaagaag
     9841 tagatgaaac aacgtttatt cgggaaatgg gactgtgaca agatgtttgt catagtccca
     9901 tttttttatt ttatttttca aaactaagaa ataccaggaa agagttcctt ttgtttgacc
     9961 ttttctttct tattgaaaac aactataata tagagtgatg ttaaaagaga agaggaattt
    10021 agtgtgcggg tattgtttat tggtgatgta gtaggttcaa tgggacgaga gatgattact
    10081 gaatatcttc ctagattgaa gaagaagtac cgtccgcaag taacgattgt aaatggtgag
    10141 aatgccgctt ctggacgtgg aatcacagaa aaaatctata aaaaattttt gcaagacggc
    10201 gtagatgtcg tgacgatggg gaatcatacg tgggacaacc gcggaatctt tgagtttgta
    10261 aatgaagcta aaaagatggt tcgtccggca aattttccgg aagggacgcc tggacaaggg
    10321 atggtctttg tcaaagtgaa ccaagtcgaa ctggcagtga tcaacatgca ggctcgttct
    10381 tttatggtgg acttggatga tccttttcgt aaaatgaatg agctggtaga agaagccaga
    10441 aaacgtacgc cgatcatttt tgtagatttt catggagaaa caacaagtga aaaacaagca
    10501 atgggctggt ttttagatgg gaaagtttca gcagtggtcg gtacacatac acacgttcag
    10561 acaaatgatg cgcgaatttt gccaagagga acagcgtatc tgacagacgt tgggatgaca
    10621 ggtccctatg atggtatttt gggtatgcgc agagaacctg taatcgaaaa gtttctgact
    10681 gcattaccaa aacgttttga agttgtggaa caaggccgat cgattttaag cggctgtatc
    10741 ttggaattgg atgatacgac aggtcatgca aaagaaatcc agctgattca gatcaacgat
    10801 gatcgaccgt tcatggagta gaaagagagg cagttttttg cagcaggagc cggaaattca
    10861 aaaagaagta aggaaactga caaaactttt aagagagaat gaaacgatca ttcgctacaa
    10921 agaacttgaa gaaaagatcc agcaaaacca gtatttagct gagttgagag aaaaaatcaa
    10981 acaagcgcaa aaagatgctg ttcattttgc ccactatgac aaaccagcag cagaaaaaga
    11041 agcaatcaaa caagcggatc aattcatgca agaatttgat cagcatccgc ttgttgtagc
    11101 ttatagaaaa cagctgttgg aagcagatga tctgcttcat catttaacaa ctatgataca
    11161 agaagaaatc aatggacaaa tagaggagga aaaacatgcc tcaaaaaact aaaaatactc
    11221 ctatgatgga acaatatcta agcatcaagg cccaatacca agatgctttt ttgttctatc
    11281 gtttaggaga cttttatgaa ctattttacg aagatgcgat caaagcgtca cagcttttgg
    11341 aattaacgtt gacgagcaga aatcgaaatg cagaagaacc tattcctatg tgcggtgtac
    11401 ctcaccatgc agcacaagga tatatcgatg ccttgattga aaaaggctat aaagtagcga
    11461 tttgcgagca ggtagaagat ccaaagacga ctaaagggat ggtcaagcgc gaagtgatcc
    11521 agctagtcac tcctggtaca gtcatggaca gcaaaggatt gtcggcaaaa gacaacaatt
    11581 ttttaacagc tgtagttagt caaggaaatg aatttggctt tgcttatgcc gatttaagta
    11641 cgggagaatt gaagacggct cggttgcatg atgaagaagc tgttttaaat gaagcctctg
    11701 cattgcagac aaaagaactc gtattaggca gtgagatcac tgataccctt cgtgaacagc
    11761 taagcgggcg tttagggcta gtcttttctc aacaaaatga gatggaagaa aacgcggaat
    11821 ttagcttttt gacaagcgaa ctagtcgatc cgctggaaaa agaagcaacc ggcaaactat
    11881 tgacttattt atcggtgaca caaaagcgga gtttagctca tatccaaaaa gcagtagaat
    11941 accaaccaga tcattttttg aaaatggatt attattcaaa attcaaccta gaattaagcc
    12001 aatctattcg gactgggaaa aagcacggca ctcttctatg gttgttagat gaaacaaaaa
    12061 cagcaatggg tggccgttta ctaaaacaat ggctagaccg tccgcttatc caggcaaaac
    12121 aaattaaagc aagacaagaa atggtcgctt ctttgctaga cagctatttt gaacgtatcg
    12181 atttgcagtc agcattaacg aaagtctatg atctggaacg cctagcaggt cgagtagctt
    12241 tcggtaatgt caatgggcga gacttgatcc agctgaaaac ttctttagaa caagtgccaa
    12301 tgatcagagg gttgattgaa ggaatcgatc aaggtcaatg gcaaagtctg ctttcagaaa
    12361 tgcagccgat ggaccatctc gtccaattga tcgaccaagc tatccaagat gatccgccgt
    12421 tacaaataac ggaaggaaac atcatcaaag atggattcaa tgagcagctc gatatgtacc
    12481 gttctgctat gagaaacgga aagaaatggt tggcagaact tgaagcaaaa gagcgtcaag
    12541 aaacaggaat caagaactta aaaatcggat ttaaccgcgt tttcggttat tatatagaaa
    12601 ttacaaaagc aaatcttgga aatgcagaac tggagaagta tgaacgaaaa caaactttag
    12661 caaatgcaga gcgtttcatc acaccagaac taaaagaatt ggagacacaa atcctcgaag
    12721 cagaagaaaa atctgttgat ttagaatatc agttgttttt agctgtgaga gaagaagtca
    12781 aaaaggctat ccagccgcta caagtacttg caaaagcaat cagtgcagta gatgtgctac
    12841 aaagttttgc aacgatcagc gaacgctatc agtatgttcg gccagaactt gtcagtgaca
    12901 agcatcagct tctgatcaaa gacggacgac atcctgtagt agaaaaagta ttaggacatc
    12961 aggaatatat ccctaacagc gtagaaatgg cagaagacga aatgatcttg ctgattacag
    13021 gaccgaatat gtctggtaaa agtacgtata tgcgacagtt ggcattaact gttctgatgg
    13081 cgcaaatggg ctgtttcgtt ccggcaaaac aagcagtttt acctattttt gatcggattt
    13141 ttacccgaat tggtgcaagt gacgacttaa ttgctggaca aagtactttt atggtagaga
    13201 tgatggaagc caatcaagcc ctgcgttatg ctacgccaaa cagtttgatt ttgtttgacg
    13261 aactagggcg aggaacagca acctatgacg gaatggcgtt ggcccaagca atcatcgaat
    13321 atatccatcg tcatgtacaa gcaaaaacac tcttttctac tcattatcat gaactgacgg
    13381 tacttgagaa agaacttccg cagcttaaaa atgtccatgt tggagccgtt gaaaaagacg
    13441 gagaagttgt cttcttgcat aaaatgatgg atggacctgc ggataaaagc tacggcatac
    13501 atgtggcaaa gatcgcagga ttgccttcca atctactaga acgagcagca gatatcctgc
    13561 atacgctaga aaatggcgat aacggacacc atactgttcc agctgaagta gaagagaaaa
    13621 ctaaaacagc caaacaggag caaataaaac cacctgcaga aaaagtaaat caagaccata
    13681 tacaagaccg tgtaaaagaa gaaaaccaac agctttcttt attcagtgaa ttatccgaaa
    13741 atgaaacaga agtcattgaa tcactgaagc aaataaattt actagaaatg acgccaatgg
    13801 atgcactaaa cacattatat gaattacaaa aacaactgta ggaagaaggc ggatatcgat
    13861 ggccaaaatc caagaattat ctgaacgttt agctaatcag atcgctgcgg gagaagtagt
    13921 ggagcgacca gcttccgttg tgaaagaatt agtggaaaat gcaattgacg ccggcagtac
    13981 tcagattgat atcttagttg aagaagcggg actgcggacg atccaagtga ttgataacgg
    14041 agaaggcatt ttggcagacg acgtagagaa tgccttcaag cggcatgcga caagtaagat
    14101 ccataatcgc gacgatcttt ttcgcatacg aacgctgggc tttcgagggg aagctttgcc
    14161 aagtattgcc tctgtttctg aaatgactct ggaaacggcg aatcaggaag aaaaacaagg
    14221 cacctatctg tcgctgaaag gcggagaagt tattgagcat cgaccagcac cactgcgtca
    14281 aggaacgaag attaccgtca gcaatctgtt tttcaatacg ccagcccgct tgaaatacgt
    14341 gaaaacactg cacacagaat tagcgaacat cggggacatc gtcaatcgac tggcattgag
    14401 tcatccatcg attgcttttc gtttagtaca tgatggaaac aaaatgctgg caactgctgg
    14461 aaatggcgat ctgaaacaaa caattgcggg aatctacgga ttatctaccg caaaaaaaat
    14521 gctgaaaatc gaaggaaaag atctagattt tgagttattt ggctatgttt cattgcctga
    14581 ggtgactcgt gccagtagga attacttatc gacgatcatc aatggacgtt ttatcaagaa
    14641 cttttccttg aataaagcaa tcgttgcagg ttatgggtca aaattaatgg tcggtcgttt
    14701 ccctattgct gtattggaaa tcaaaatgga cccgctttta gtagatgtaa atgttcatcc
    14761 gacgaagcag gaagtccggc tgtcgaagga aaaagaacta acagagctaa ttagtaacgc
    14821 cattcaaaaa gcattgtctc aagaaaatct gattccaagt gcagcggata atctacggtt
    14881 taagaaaaaa gtacctgatc agcctaaaac agaacaaatc gaaatcgatt tgtcctacgc
    14941 ttttgaagaa gaaaaaccta aaaagccaag tagtttgaat tttgatcgag agacaggtac
    15001 ctttttcgta gaagaactaa agaacacatt tgttgacaga attgttgata agtctgtgga
    15061 aaatgttgaa aactattctg gtttttctga agaaaacacc acttatccag aaaaaacagc
    15121 gaaaacggtg gataagtttg gtgaaaatgt tgataacttt gtagaaaaaa cagtggaaaa
    15181 atctgaaaag aaagaatttc ccattgtgga taacatggag aaaacaaatg aagaacaagc
    15241 agataaatcc gtagaagagg atgaaaagat ttacgaggaa gaattgacac tccatcctga
    15301 atttgatttc actcaaggaa acgacaaaac attagaacaa gccatcaaga aattagaaac
    15361 ggaaaaacca gtacaacgtt ttcctcagtt ggaatatttt ggacagatgc acggaacgta
    15421 tctttttgcc caaagtagcg atgggttgta catcattgat cagcatgctg cccaagagcg
    15481 cattaagtat gaatatttcc gggaaaaaat tggggaagta tctgatgatc tgcaagaatt
    15541 gcttgttcca tttgtgttag actatccaaa cagtgatgct ttgaaattaa aagagcaaaa
    15601 acacttgcta gaagatgcag ggatttattt agaagaattt ggtcaaaaca gctttattgt
    15661 acgggcccat cctacttggt atcccaatgg agaagaagaa tcgattattc gggagatgat
    15721 cgatatgctg ctgacaactg gaagtgtgag tgtaaaaaaa ttccgtgaag caacagcaat
    15781 catgatgagt tgcaaacgat cgattaaagc caaccattat ttgaatgaag cacaagcacg
    15841 tgtgctgctg aaggatctgg cacgatgcga aaatcctttc aattgtcccc atggccgtcc
    15901 agtattgatt cactttacca attcggatat ggaaaggatg ttcaaacgaa tccaagaccc
    15961 gcattaagtc aaagagaaga gggaaaacat gaagattgta ttagcatccc aatcaccaag
    16021 aagaaaagag ttattggctc atatcgtttc agaattcgag attgaacctg ctgatatcga
    16081 tgaaacgcca tttccagacg aacagcccgt cgattatgtt cgtagaatgg ctgaagaaaa
    16141 agcacgaact gtctgggaac aagatgaaaa agaagaccat ttagtgattg ccagtgacac
    16201 gactgttgtt ctcaatcaag agatcatggg taaaccagaa gatctggctg aggctgaatt
    16261 catgctgaaa aaactaagcg gggaaacaca tactgtatat acagctgttg ttttaaaaac
    16321 aaaggaacga gaagaacgga tactagcaga agcacatgtc actttttatc ctttgacaga
    16381 cgaagagatc aaacgctact tggagacggg ggattatgcg gataaggcag gggcatacgg
    16441 catccaaaat gctgcgagtg tattcgtcaa agaaatttct ggagattatt acagtatcgt
    16501 aggatttccg attggtgctg tcaatcaggc actgaaaaca ttcatttaaa caaaaaagcg
    16561 gactatctga ttttcgattg aaaatccatg atagcccgtt ttttttattg aaaagattac
    16621 ttatctactc tgactaagat tttacttcag ctttaccgac tgcttcgccc gggcgaacaa
    16681 gtcctgattg gtcaagagaa agtcctgcaa ctttttcatt attggtcaaa gcaacaataa
    16741 tgtcagtttt cttgccagct tgttctattt ctggcaaatc catttcagca atcagggtct
    16801 ctggtgtgac aaggtatcct tctttcacga atacattgaa aggaacaccc tttagttcaa
    16861 cagtatctaa tcccatgtga acaagtactt ccagcccctc attagaaaga ataccaatgg
    16921 catgttttgt ttcaaagaca ctcgtcactt taccgtttac tggtgcatag actttgccgt
    16981 ttgacggttc gacagcataa ccgtcaccca tcattttttg tgagaaaact gggtcattta
    17041 cttcagttat ttccttgatg gtccctgcag cgactgcgaa taatgtttct tttgttgcaa
    17101 ctgccgtacc agttgctgaa acaggttcga aagactgtgg cgttgctgtt gcgccatttg
    17161 ctgtttgaag ttgtacatca gcagcatttt caggaacagc aggatcaatc ttattcaaaa
    17221 ttccctgacg tctaaagatg atcgtcaagc caaatggaat gatgacagca atgatcattg
    17281 cgatgatgaa aggtacccat gtttctgctt ggatagctag tattcctggc aaaccgccta
    17341 ctccgatcgc gttagctcga acacccatca agttagcaaa catgccagct aatccagagc
    17401 cgaccattgc agcgacgaaa ggatagacgt atttcaaatt gattccgaac atagcaggtt
    17461 cagttacgcc taagtaacaa gaaatcattg ctggaatcga gatttgttct tcttttttat
    17521 tcccacgatg taagaagatg atggctaaga ctgcagagcc ttgggcgata tttgataaag
    17581 caatcatcgg ccataaattc gttgatccga aatctgcaat cagctgcata tcgatggcat
    17641 tggtcatatg gtggagacca gtaatcacta aaggagcata caggaatccg aatacggcac
    17701 taaacaacca gctgatagaa gacgtcaatc cagtatttac gatatttgag atccagcttc
    17761 cgactgtcca gccgatagga cctaaaataa cgtgtgcagc taaaacagtt ggtaacaatg
    17821 aaaacaatgg aacaaaaatc atcgagatcg actgagggat atatttgcgg aagaagattt
    17881 ctagatacgc taacataaac cctgccagca tggctggaat aacttgcgct tgataaccaa
    17941 tcatctggac ttgagcaaaa ccaaaatccc aaaatggaat atctgctgcg gctgtggaag
    18001 ctacactata agcatttaat aattgcggag aaactaacgt aattcctaaa acgattccta
    18061 atatttgtgt agtacccatc ttttttgcaa tactccaagt aatacctact ggaagaaaat
    18121 ggaaaattgc ttcacccggt aaccacaaaa aggcattgac accattccaa aacttcgagt
    18181 gttcaacgat tgttccacca agactttcaa actggatacc ttcaagtaca tttctgaatc
    18241 caaggatcaa tccaccgaca atgattgcag gaatcagtgg tgtaaagatt tctgctaaaa
    18301 cggcaatagc acgttgaacg ggatgaaggt tttgttttgc agctgctttt ccttgttctt
    18361 tggaaacccc ttcaactcca gatactgcaa cgaagtcgtt ataaaaagta gaaacatcgt
    18421 ttcctatgat gacttggaac tgtcctgcat tcgtgaacat cccttttacg ctaggtatat
    18481 cttcgatcgc tttttcgtcc gcttttcctg gatcattcag gacaaaacgc atacgagtcg
    18541 cacaatgact aactgcagca atattttctt ttccgccgat atcatgtaac agcttctcgg
    18601 catctgcttg atattttgcc atatcaataa acccctttct cttaacttgt ctatgcaagt
    18661 tgtttcttca tttactatac tttttttcgg agagaattgc aagcgtttta ttaaaaagta
    18721 cgagagaaaa tgatatcgtt ttaaaaagct taaaataagc ttttcttaaa aataggaaca
    18781 ttgaaataca aaaagagctg tagtatagtg aagaaatgat ggaagaacga gtgagggaaa
    18841 aaacatgaat aagttcaatg aaattttttt agatttggaa cagaaaattt tagcgaaaga
    18901 atatcctccg cattcgcttt tacccagtga gaaccaattg atcaaaattt atggtgtttc
    18961 acgagaaaca attagaaaag cgctgaatct tttgactacg gaaggttata ttcaaaaaaa
    19021 acaaggaaaa ggttcgatcg tactggatcg gaatcgcttc gactttccta tttctggatt
    19081 gactagctat aaagagctac aggagaccca acgtattcca agtgaaacga tcatccatac
    19141 gttagaagaa acagaagtga caaaagcatt gaacgagatc actggctggg agatcggtgc
    19201 gcctgtttgg catttgatac gcgaaagaaa aatcaatggc gaagtagtta tattagacac
    19261 cgattatcta ttaaaggaaa tcgttcctat tttaactcca gcacaagcac aaggatcgat
    19321 ctatgaatat tttgaaaatg agctttcttt gacgattgct tacgcgcaaa aggagatcac
    19381 agtagaagaa gtaacggaaa tcatgaaaac agcgatggat cttcacgatg acacttatgc
    19441 agtagtagtc agaagcctcg ttcatctgga agatacccgc tgtttcgagt attctgagtc
    19501 ggttcaccga ttagataaat tccgtttcgt tgagtttgcc cgacgccgaa aagtgtaaat
    19561 agttcaaaag aaagcaaatt gttggcatct gtccactttg gcgctatgat aggatcacaa
    19621 agggggcatt tttaatggat aaaccaataa gaccagaaaa agaagaactg aaagaaaagt
    19681 tatcacccat ggcttatgca gtcacacaag aaaatgcaac agaacgacca tttagcggga
    19741 aatatgatga tttttacgaa aaggggatct atgtagatat cgtcagcggt gaaccgttat
    19801 tcagctctgc agaaaaatat gatgcaggtt gtggctggcc atcattcagc aaaccaataa
    19861 cgaaaagaca agtgcgcgaa aaagccgatt tttctcatgg catgcatcga atagaagttc
    19921 gaagcaaaga agcagattct catctcggac atgtgtttac cgatggacca gtagatcaag
    19981 gtggtctacg ttactgcatc aattctgcct cactgaaatt cattccatat gaaaagatgg
    20041 atgaattagg ttatggggaa ttcaaatcac ttgtagaata atggaaatac acaaagagcg
    20101 gtacaatacg gggatttact cgatcgtccg ctcttttttt attcaagcga ttgctatttg
    20161 aaagaaacgc tccctagact ccttttttca caaggtgaaa tgtgctacaa taaagggaac
    20221 gtatgtgtgc aaaagaaaga ggactagaat atgtatgaat atctgacagg tgtggttacc
    20281 tttatcaacc cctattacat agtagtagaa accaatggta tcggctacca gatcgcacta
    20341 ggaaatcctt accgctacag tagcaaacta aatcaaaaaa taaaaattta tgtccatcag
    20401 gtaatacgtg aagatgcgca tcttctgtat ggatttgatt cgctagaaga aaagcaactg
    20461 tttttgcgat tagtaagtgt ttcaggaatc ggtccgaaaa gtgcccttgc aatcatggca
    20521 agcgaagacc actccggttt gattcaagca gtagaatcca gtgatgtcac ttatttgacg
    20581 aaatttccag gagtagggaa aaagacagca caacaaatga tcttggatct aaaaggaaaa
    20641 ttcggtgagc tgagtatcga tacacctttt agtctatttg atgaagcaaa cacaaaagac
    20701 gctacagctc tatctgaagc aatggaagct ctctcggctc ttggttacag tgatcgagaa
    20761 atcaaacgtg tagaaaaaca attaaaagaa gtagataatc agacaacgga tgagtatcta
    20821 cgccaagcac tcaagctaat gatgaaaaaa taaggaggag accaaatgac agatgaatac
    20881 ttgttatcac cagaatctgg cgaaaatgaa ctgagtttgg aaaaatctct tcgaccacag
    20941 ctgctttctc aatatatcgg acagagaaaa gtcaaacaag aacttcagat ttacatcgaa
    21001 gctgccagaa atcgggaaga acctttagat catgttctgt tgtacgggcc tcctggatta
    21061 ggaaaaacga cgatggccat ggtcattgct aatgagatga ccgtaaatat tcgtacgacg
    21121 agtggccctg ctatcgaacg tccgggtgac ttagtagcaa tcttgaatga actggaagca
    21181 ggggatgtcc tgtttatcga tgagatccat cgattaccta gagtggtaga agagatgctt
    21241 tattcagcta tggaagattt ctatgtagat atcatggtag gacaagggcc aaccgcacat
    21301 ccggttcatt tccctcttcc tccctttact ttgattggcg cgacgacacg ggcaggtatg
    21361 ctttctgcac ctttacgaga tcgatttggc atcatttctc atatggaata ttatgacgaa
    21421 caggatctgc aggagatcgt tttacgttct tcggatattt ttcaaacaga gatcattgaa
    21481 gaaggggcat tggaaattgc tcgccgatca cgaggaacgc ctagaatcgc taatcgcttg
    21541 ctcaaacggg ttcgtgattt tgcgcaagtc caaggagacg ggaaaatcga tcgtcctata
    21601 gcggatcagg cacttacttt gctacaggtc gatcaggctg gattggatta tgttgaccag
    21661 aaattgttgc gaacaatgat cgagttatat ggcggcggac cagtagggtt aagtacgctt
    21721 tcagtaaaca taggagaaga gcgtgagacg gtagaagata tgtatgaacc gtatctgatc
    21781 caaaaaggat ttttaaagcg tacacctaga gggcgaattg ctactgctta tgcctatgaa
    21841 cattttggtt acgactatca tatatgattt ttgcttttag attggaggaa aatgaatgag
    21901 tgatacaaca cgtacgaaac aattgatcaa aaacgtattg attgatttgt gccaaacgca
    21961 atcttttcga aaaatcagcg tccaaaaaat cgcaaacgaa gcaaaaatca atcgacaaac
    22021 attttattat cattttacag ataaatacga tttgcttcgt tgggtctatt gtgaggatgc
    22081 attgcattat ttagatccac aatgtctttc acttgataat tgggaagagc aagcattgaa
    22141 aatgctgaaa gcaattgctg agaagaaaga attttatgca aatactgtgc tttctgaccc
    22201 agaaatttta caaaaagagt tttctcaact gatccaaaaa tcatttatca agatttttga
    22261 acaaatggat gaagaaagac aactttctgc aagagacaaa ctattttatg ctcgtttttt
    22321 ttcttacggt tgcagtggtg tattagtcaa ttggatcacg aatgaatatg aagaaacacc
    22381 gatggaaatc gctatgcagc ttttccgttt agccaaggat acggaattat attcttatcg
    22441 tctttatgca aaagaagagt tggaagaaca gtaatagaaa aattttttgt tggaaaagca
    22501 ataatcgcta aaaggagatg gggaaatgac aaaaatttta tttgtttgtt tgggaaatat
    22561 ttgccgttca ccgatggcag aaggcttgct gagaaaacga atagcattag aaggaaggga
    22621 agcagaattt tttgtggatt ctgctgctac aagcacgtat gaagttggaa agacaccgca
    22681 ccctggaacg aaaaaaatat taaaccaaga aaaagtagat atgacgaata tggttgctcg
    22741 gcaaatcaca ccccacgatt ttgaaacttt tgattggatc attggcatgg atcaagaaaa
    22801 tgtagaagaa ctgaaacgaa gagcaccacg ctcagcgcag gggaaaatcc atttgttttt
    22861 aagtagcatt cctggaaaag aaaaagaaaa tgttcccgac ccatactata ccaataactt
    22921 tgatgagaca tatcacttga tcacagaagg cctgaatcat tggtggaata tttggattga
    22981 tgaaaataaa ataacaaata atttgtaaag ttaacgcttt ctttttaagg cgatgttaga
    23041 gcatttcctt gtttttttgt aaaatgttag gtaaaataaa attaattaag taacactttc
    23101 ttagctaaag gaggagtgca ttcgatgaac gaagagacag tatcgccaat gaagaagctt
    23161 acgaagttag ttactcatac ttcgtatcaa ctttttgatt cttttgtaaa tgacactgaa
    23221 gaacatgcta agaatgtacg attgcaagga aagtttattc ttgagctgca aaaagctgct
    23281 actgaacata gtctagttat cttacaagta agagcaaatc gtttgagtag caagtatgaa
    23341 acgatctcag gctgggtggc gacaaaaacg gtcgaaaaag accgagtgat gatccgccta
    23401 caaaacgaag agcagcagat ccggatggtt cctgtagaac aaattgaaaa aataacaatc
    23461 ctttcaccag caggggaaca ggaacggtta tcaaaataat ttataccaga tagaaaagca
    23521 cgtatgagct tgtaccatca atcattacta atcaaaaata accgaatgct ttaagctgat
    23581 atcagtaaaa cggaacgttt taggatgagt atcatagcat gacagcattc ggttgattag
    23641 ttgaatcgat tggatggtac aagttttttt gataaaaaaa ggtcctgcta gccggggagc
    23701 tagcaggata aggagttaaa aatgaaaaag tgttgttagg gttgtttgtt ggtatgctta
    23761 tataatagtc attagttgtg aatattttgt gacgaaagtt ttcgaaagtt gttaag
//
LOCUS       DAXQKX010000039        23795 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.039, whole genome shotgun sequence.
ACCESSION   DAXQKX010000039 DAXQKX010000000
VERSION     DAXQKX010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23795
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.039"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            23..646
                     /locus_tag="ACF3MF_001756"
     CDS             23..646
                     /locus_tag="ACF3MF_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927742.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1096..2145
                     /gene="trpX"
                     /locus_tag="ACF3MF_001757"
     CDS             1096..2145
                     /gene="trpX"
                     /locus_tag="ACF3MF_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HFE3927743.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2142..3023
                     /locus_tag="ACF3MF_001758"
     CDS             2142..3023
                     /locus_tag="ACF3MF_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFE3927744.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3026..3796
                     /locus_tag="ACF3MF_001759"
     CDS             3026..3796
                     /locus_tag="ACF3MF_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3927745.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4075..4929
                     /gene="aroE"
                     /locus_tag="ACF3MF_001760"
     CDS             4075..4929
                     /gene="aroE"
                     /locus_tag="ACF3MF_001760"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HFE3927746.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5107..6270
                     /locus_tag="ACF3MF_001761"
     CDS             5107..6270
                     /locus_tag="ACF3MF_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFE3927747.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6387..6797
                     /locus_tag="ACF3MF_001762"
     CDS             6387..6797
                     /locus_tag="ACF3MF_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFE3927748.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6971..9199
                     /gene="topB"
                     /locus_tag="ACF3MF_001763"
     CDS             6971..9199
                     /gene="topB"
                     /locus_tag="ACF3MF_001763"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFE3927749.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9370..9654
                     /locus_tag="ACF3MF_001764"
     CDS             9370..9654
                     /locus_tag="ACF3MF_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927750.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            9814..10050
                     /locus_tag="ACF3MF_001765"
     CDS             9814..10050
                     /locus_tag="ACF3MF_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFE3927751.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10047..10445
                     /locus_tag="ACF3MF_001766"
     CDS             10047..10445
                     /locus_tag="ACF3MF_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HFE3927752.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
     gene            complement(11112..12056)
                     /locus_tag="ACF3MF_001767"
     CDS             complement(11112..12056)
                     /locus_tag="ACF3MF_001767"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFE3927753.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(12352..13296)
                     /locus_tag="ACF3MF_001768"
     CDS             complement(12352..13296)
                     /locus_tag="ACF3MF_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFE3927754.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            13517..14731
                     /locus_tag="ACF3MF_001769"
     CDS             13517..14731
                     /locus_tag="ACF3MF_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFE3927755.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASIYGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            14753..16768
                     /locus_tag="ACF3MF_001770"
     CDS             14753..16768
                     /locus_tag="ACF3MF_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-rhamnosidase"
                     /protein_id="HFE3927756.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEETFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(16851..18224)
                     /locus_tag="ACF3MF_001771"
     CDS             complement(16851..18224)
                     /locus_tag="ACF3MF_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFE3927757.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIISFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(18250..18534)
                     /locus_tag="ACF3MF_001772"
     CDS             complement(18250..18534)
                     /locus_tag="ACF3MF_001772"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFE3927758.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(18536..20551)
                     /locus_tag="ACF3MF_001773"
     CDS             complement(18536..20551)
                     /locus_tag="ACF3MF_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFE3927759.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(20730..21035)
                     /locus_tag="ACF3MF_001774"
     CDS             complement(20730..21035)
                     /locus_tag="ACF3MF_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HFE3927760.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(21124..22155)
                     /locus_tag="ACF3MF_001775"
     CDS             complement(21124..22155)
                     /locus_tag="ACF3MF_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFE3927761.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            22362..23237
                     /locus_tag="ACF3MF_001776"
     CDS             22362..23237
                     /locus_tag="ACF3MF_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFE3927762.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(23389..>23795)
                     /locus_tag="ACF3MF_001777"
     CDS             complement(23389..>23795)
                     /locus_tag="ACF3MF_001777"
                     /EC_number="3.4.22.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004197 - cysteine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0016485 - protein processing [Evidence
                     IEA];
                     GO_process: GO:0045184 - establishment of protein
                     localization [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HFE3927763.1"
                     /translation="VISSHRGLPQAKLFTDLPKLTLGDSFYIEINGRTLAYQVDQIKT
                     VEPTDTKDLRIEKGQDFVTLLTCTPYMVNSHRLLVRGHRVPYHAKEVQKEVQKVSENK
                     RFFLYGLLAACILIFLLLIYLFRQSFKIRNRS"
BASE COUNT         7736 a         4237 c         4610 g         7212 t
ORIGIN      
        1 aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat cgagagtaca
       61 agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt attttcgacg
      121 tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt tattgccgga
      181 aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa ccagcaaatt
      241 gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg cgatatcggt
      301 gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt ttaatgatcc
      361 tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt atgatgtaca
      421 tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt tctttgatgg
      481 aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt ttgataagga
      541 gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag aagaagaatt
      601 ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca ttggcgcgat
      661 gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg tttgatcttc
      721 aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt cgattagact
      781 taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt atttcagcag
      841 aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg agactttccc
      901 atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga catgaacatt
      961 gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga ccgctttggc
     1021 cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa agattgactt
     1081 tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat tattttagtt
     1141 tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag tacttcgacg
     1201 aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca tccggcatta
     1261 gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa agaaggagaa
     1321 aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc cacaatgagt
     1381 caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc tgccgctcaa
     1441 tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac ggatcctgtg
     1501 ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg tgtttctgat
     1561 cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa tgcaaaaaaa
     1621 gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc acaagcagaa
     1681 gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc cactaatgag
     1741 attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt tccattagat
     1801 aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc aaatatcccc
     1861 gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat cgggatcaat
     1921 caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag tggaaaagaa
     1981 aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat caatcaatct
     2041 caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc caaaatcatt
     2101 acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta tcagctattt
     2161 cacaaggcat gctttgggca atattaggat tagggatttt catgacttat cggatcttag
     2221 actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc tgtgtgacag
     2281 ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt gctggcatga
     2341 tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt attttagcag
     2401 ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga acaccaaatc
     2461 tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg ttacctgatt
     2521 actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct gtactgctat
     2581 tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac gaaacgatgg
     2641 ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact ttgtcgaacg
     2701 gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca gatgtaaata
     2761 aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa gtgatcttcc
     2821 aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc atttatcagc
     2881 tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag ttgttctccg
     2941 ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg aacttaaaaa
     3001 cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa atggcagaaa
     3061 agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta accttacaat
     3121 cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa gcacactgtt
     3181 caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta aagatcagct
     3241 gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt tccaagaccc
     3301 caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg cacaaaaaag
     3361 aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag attttttcag
     3421 actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag cgggtgaatt
     3481 atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag ctcctgagtt
     3541 actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag cattaatgcg
     3601 attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca cgcatcgaat
     3661 ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga aaatcgttca
     3721 agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc agttctttga
     3781 agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact tgaaaactca
     3841 ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa catatttggg
     3901 tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt ctttgctctg
     3961 acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc gtactttttc
     4021 gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa taagatgatt
     4081 tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag tttatcccca
     4141 ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt agctttccaa
     4201 gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga tatgttaggt
     4261 gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga ggtaagccag
     4321 gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg tttgattggc
     4381 tataataccg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat ttcgatcaaa
     4441 aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac tgttcaagct
     4501 gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac attcgctcaa
     4561 gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa agttcgtgac
     4621 tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct agtcaatgca
     4681 acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat aagcatgatg
     4741 catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg tttattaaaa
     4801 gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat ctaccaagga
     4861 gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat tgaaaagctg
     4921 tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg gtctcaagaa
     4981 aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat tatcaaaaaa
     5041 tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa acgaggagga
     5101 accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa acctctgaag
     5161 cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat ggaaaatgag
     5221 gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt gaaccaatac
     5281 gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa taaaaaattt
     5341 ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc gtggaaaaaa
     5401 atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt ttttattggt
     5461 aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac ctttcatggg
     5521 caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac acgcggagaa
     5581 gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc ccataagccg
     5641 aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg acaaaataag
     5701 atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt agtagaaaat
     5761 tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga aaaagtgatc
     5821 gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa tctggatggt
     5881 gtagatatta aaaaaggggt ccagaagatg gatggacatg ttcttttgca gtacgcacgt
     5941 ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca agtaatgaac
     6001 gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta tgcagctggt
     6061 aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa aaacctcttt
     6121 tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga cggttcgtgg
     6181 aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca aatgaatcaa
     6241 tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag aagctgcgca
     6301 aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc ttatggtaga
     6361 tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa aatgagtcgc
     6421 gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt atcaccacat
     6481 acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa aatctaatca
     6541 cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg ccagaaggaa
     6601 ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca agaaatgaag
     6661 aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag atgccactgg
     6721 atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc atcaactggc
     6781 agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa gcagcaaacg
     6841 gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt atcttttttt
     6901 tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat taagtaacgg
     6961 aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa aagcctatgc
     7021 cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg atccattgtt
     7081 tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg ttgctccagg
     7141 agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt tcccagaaac
     7201 cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa aacgagaatt
     7261 gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg aagccatcgc
     7321 gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt tacgtttatg
     7381 gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc aacctggaaa
     7441 gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt ggctgattgg
     7501 aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg atggcagttt
     7561 ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc aagaagaaat
     7621 caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga caaacaaagg
     7681 gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag agttaacgaa
     7741 ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc ttgaagttac
     7801 gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt tgcagacaaa
     7861 gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc aaggattgta
     7921 cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag aaaatgagca
     7981 tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag aagaagtaca
     8041 gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc aagaacatca
     8101 tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc tttccaaatt
     8161 acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg ctgcagatta
     8221 tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa aaagcatcgg
     8281 aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa aaaagaaaga
     8341 agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac tgaaaagtat
     8401 ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca cagcaatgaa
     8461 aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag aagtagaagg
     8521 aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga agcattacat
     8581 cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt gtaaggcagt
     8641 agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag ggtacttgag
     8701 aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca aaaaattcat
     8761 cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt cagatgagat
     8821 tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag gaagatgtcc
     8881 aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct tgaatccgga
     8941 atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa cgaatctcag
     9001 agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg gtaaaaaagg
     9061 gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt cttttccatg
     9121 gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa gaaaaaataa
     9181 tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt ccgaaaagtg
     9241 agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa cgttggggta
     9301 ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca ttcattttta
     9361 aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct aaagtatcct
     9421 gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc accaacgttg
     9481 attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca taaaacgaca
     9541 agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc ggctatgatc
     9601 attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg ttaagaatac
     9661 gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt tcgtaagaaa
     9721 aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa tgtacttact
     9781 atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa gtataaaatt
     9841 agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga attcatgggt
     9901 gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt acgaatgatc
     9961 aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa tcaatatgaa
    10021 gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa attatcaaaa
    10081 tcaacgcgaa agttatttta cgtcactcgc caggcgaaat gatcggtgta aaagatgcaa
    10141 atgcattaga tatggccgtc aaacagcctt cacaagcagt attcaatcaa gaactctatc
    10201 ctgaaatcta tgaaaaagcg gcgattttag caattaattt agctaaaaaa catccttttc
    10261 ataatggcaa taaacgaact gctcttgttg ccatgttgtt gtttcttcaa ttgaataatt
    10321 gtccagttgc tttttctcgt caagaagctg ttgattttat cataatgatt accactagtt
    10381 cattggattt cgattcacta aagtccaaga taaccagtta tttacgacaa accgcaataa
    10441 aatgaacgaa ttaaaaactt tatttctcaa ttagatcagc atgtcattaa ggaatatgct
    10501 gattttttta tgtttaatca tacaaaatag ttttttcata aaaatatgga aaatatggat
    10561 taattttgaa ataattgatt taaaaggaat acaaaagagt gaatagtagg aaatagtggt
    10621 ttagaactag tgggctgatt ttttatatat tttagtttac ataatatata ttatacaaag
    10681 tagatttaaa aaatgataaa cctctctcga acggtttttt atcaaaaatc gtcatttttc
    10741 catcaaaatc tgcttatgca aaattataaa aaaattttgc agtttttctt actttttttg
    10801 tcgtttaatt gaatgataaa aaccagtttc tttattcagt taatcaaata tgaacgaatt
    10861 agatatgaat cattgtattt gccgttgcgg aaggattttt taattaacca cagataaaca
    10921 ttgataacga ttcgcttatt gtaatcaaca gattaaattt catatgttca tatgtacgga
    10981 tacattttcg gaccgattaa ttttaaccat tctgtttatt tgcttaccta ttagatatca
    11041 ataaaaaact gcttaacagc tatttcagct gttaagcagt tttaggattt ttagttcata
    11101 ttcattgttt cttataatac agtgttcaat acttctctta aagcacttgt tgatttgctg
    11161 aacattgctt tttcttcttc gttgattgat aattcaacaa cttcacgaac accattttcg
    11221 tcaacgattg atggcacacc tgtaaagata tctttttcgt cgtattcacc agttaaataa
    11281 gcagatacag gcaatacagc ttgttcgtta ttcaagatag cttttacgat acgtgcagta
    11341 ctcataccaa taccatagta agttgctttt ttacgatcaa tgatctcata agcagcatta
    11401 cggactttat cagcaatcac atctaattca tcttgggcaa tacgatggtc tttttctaca
    11461 atttcaaaca ctggtttacc accgacagtt gtatgtgacc atgcagcaac ttctgaatca
    11521 ccatgttcac ctaagatata gccgtggacg ctgcgtgggt caacttttaa tttcaatgcg
    11581 atttctttac ggaaacgagt tgtatccaat gttgttccag taccgataac acgtgatgtt
    11641 ggcagaccag attcgttcca agcgatatat gtcaaaatat ctactgggtt tgaagcaaca
    11701 acgataatac cgtcgaatcc tgatcccatg atttctttta cgatttggcg catgattgac
    11761 gcatttgttt taactaaatc taaacgagat tgaccaggtt tttggttgat accagctgtg
    11821 ataacaacga tatcagcatc tttacattct tcatagccac ctgaccatac agccacattt
    11881 tcatcgcccc aagccatacc atctaaaagg tccaatgctt ccccttctgc tttttcttga
    11941 ttcacatcga tcaatactaa ttcattagag attccttggt tgatcattgc ataagcgata
    12001 cttgttccaa caaaacctgt accgacgatt actactttac gacttgtttt tttcatgaat
    12061 aaacagctcc ttttcataac tatttgttac tttcatgaaa agtatagtct tgtttattca
    12121 ttttatcaac atgttaatta taatagttgt tattataatt tttgatggaa acgaattcct
    12181 gaatacgcat aacagataaa tgacaaatgt ttacacctat atcccctgat aatacaacca
    12241 aaagtttaga actgaaaata aatccaaaaa aattcgctgc aacgatataa taagacagca
    12301 atcgcaccta aaacaatttt ccttcatatg ctttagtgaa agattttctt cttaatgttt
    12361 atttctccat tcattgggag tacatgttga atacttcttg aataatttga ataaagaagt
    12421 cgtttgttta tatccgatac gattagcgat ttcttccaac gaaaaactcg tttcttgaat
    12481 cagttccaac gcaaagtcga attttttctt tagaaccagt tcttgaaagg aagcatcaaa
    12541 atacattttc aatttattac taagatagac cggattgtag ccaaaatgag ctgctgtttc
    12601 ttttaacgta caagaagtaa aatgcttatc gatataatct aatactctaa gcatctcatt
    12661 ttctgcgcat ccatctgctg atgaaaagct ttgttgttct aataaatgag tcaattcgat
    12721 cagtaatagt gatgtataga gatttaacga acggatctta tgactgtatg tatcaaaata
    12781 aatcaacagc atattttcaa tcaaatgcgt caaacgactt gtttttccgc cgcgaaaatg
    12841 aatgaattgt gtatgttccc ctttttcttt tgatgcattt atcaaaaaag aagaaagtag
    12901 attatttgtg cttgccaaat gattcaatat ctctgtagat aaggtttctt cttttaataa
    12961 gatgttgatt aaaatatcct cttgccctgt gtattcgatt ctttgagtag cttctttatc
    13021 aatgatcacc acgtcacttt cttccatctc tatcctttct ccattaataa tttgtaaaca
    13081 tgtaccgcta tacatataat tgatttcaac aaaatcatgt gtatgctcgg gaacttccgc
    13141 atatcgacgg tgtttactga tatgaatatt tccctgttga aatagatccc ctcggtggat
    13201 ttttggcggt gtctgaagat ggtaagctaa gtttaaatca ttgatattca ttccttgttc
    13261 acgctgcaga gtttcgattg attcttcgtt acgcaaaaaa aatgtctaat tcagctagtt
    13321 ccaattgact ccctcctttt tgtaagcggt ttctttcgct tattagttca cgctgtactg
    13381 ctattatatg caaagctatt tttggtttca taaagacttt ctatggttgg gacatgaact
    13441 tcctgtgatt ccgctattga gagaataacc acttcatact atatttttga taagcgctta
    13501 caaaaatgaa aggaacatgc ttatgaataa aaagatgatg aaattttctc tgctgtcagt
    13561 ctctcttatt ttgacttctg ctggtgcagt cacgtctgca attcccagta tgtcagctac
    13621 ttatgccacg cgttctttat ctgctgttga attattaacg actgctccct cttttatggt
    13681 cactattttt gttttgatta gtagttttat tgctaggaaa atcggacaaa aacaaactgt
    13741 gatcatcgga ttagtgattg catcgattta tggtatcctc cccctcttct cacaaagtta
    13801 cagtattgtc ttagcttcaa gagctggact aggtattggc tttggattga tcaattcttt
    13861 ggcagtcagc atgattgctg ccttttatca cggagatgaa cgagcctcta tgattggttt
    13921 tcaaagtgca tttcaaggat ttggtgcagc tttaatgaca tttgttgcag gacagctagt
    13981 acagttcggt tggcaatata cctttttagt ctacgccatc agcttaccta ttcttgtctt
    14041 gtttgttttg tttgttccta cacctgaaac aactgaactt caatcacatg gcacagcccc
    14101 aacaagacaa gtaatcaaaa cgaatcctaa aatgattagt tatggtattt ttctcttgct
    14161 ggtcatcgtg gtatataatg ctgtatcgat taaattagcc acagtcctga cgacttattc
    14221 tctaggaaac gaaactaatg cagcgaatat cttaacaatc atgcaattgg caagtatggc
    14281 tgccggagtt tgttttggct ggcttcagac aaaagcacat cgctatatgc ttacactttc
    14341 tttactactg atgggaatcg gctttgtatt gattgccact gtgataaacc tgtatgtgat
    14401 tgggtttggt gcgatcctaa caggaatttc tttttcgtta ttcattcctt acttattcaa
    14461 ccaagtaagt atccaagcgc ccaagtacgc ggagagtttc aatacttcaa tcttattggt
    14521 tggcgctaat ttaggtactt tcattgcacc atatggtttg ctctttctct cttttgcttc
    14581 tcttgggagt aaaacacttg ctgttttcgt caatggcagt atcttgctgt tgattagcgc
    14641 gcttattagc cttctagtag tacacaggac gaatagaaag acagtgataa gagtagatga
    14701 agaaataaaa gaacaattga caacaaaata aatttgatgg aggtcgtgta aaatgacaaa
    14761 tgaaaaacat aaagatagat ggctttggta tcctggagac tttgagatcc gccatggact
    14821 gctacaaaat ttccaacggg aagaacgagg ttttgactgg ccagcgtact ggtacatgga
    14881 tgattgccat cggaacgtca agtttaagag atattacttt cttgatcaac cttccatgtt
    14941 taaagtgacg atccaaggag ttgggtatgt agaaattaat ggacaaaaac atccatgtgg
    15001 aaaatggctg acttgtccag ctggtaaagc aaaaattcgt atctttgtag gacatacatc
    15061 agggctacca gcgatgttta tcgagggaga cgaagtaaaa tcagatattg gctggacagc
    15121 aagtaatttt attgaagaat atccagctgg ctggagtccg ctttatgtcg atatcgcaaa
    15181 agatccaaat caaatctatt atcaaaaaga atgcgtccat ccagtcactg aaacggagat
    15241 tggcggagga atcttattcg attttgggcg agcagtgaat ggctgtgtag aactaatatc
    15301 tctggatgac catatcgaat ctatcactct atgttatgga gagtccgatg tagaagctat
    15361 ggatatcgat tattgctact ataagcaaat aggaatgaca agaaaaatga aagctcgtaa
    15421 acgcgctttt cgctatttgt ttataccaga ggtttctact ggaatggttc aacttcaagt
    15481 ttttcatgaa tttttatctc tttcgaaaca agctgctttt tcaagcgatt cttctttact
    15541 gaatcagatc tggtcagtat cagaagaaac cttcaagtta tgtagtgatt tgttttttat
    15601 cgacggtatc aaacgagatc gctggatttg gtctggagat gcgtatcaat cattcatgat
    15661 caatcaatat cttttttttg acgaggaaat caataaacga acgatattag cattaagagg
    15721 acaaaatgaa atcaagcagc atatgaatac tatcgttgac tattcgatct tgtggttgat
    15781 tggtatcgaa aaccactata tgatgacgaa agactatgaa tttttacgca tcgtctaccc
    15841 taagatgcaa tcattaatga gatacttgat ggagcaaacg aatgaattag ggtttattta
    15901 tgggagagca aaagattgga tatttattga ttggtctgaa atggataaag aaggaactct
    15961 tgctgcagaa caagtcttat tactgaaagc ctatcattcc atgatcactt gcggagatat
    16021 cttagctgaa acatatggag agaacgaaaa ttatcatact catctctatc aagaaaaata
    16081 tcaactattg aaacaaaacc tatttgacta cttttgggat gaagaacttg gcgcttttat
    16141 cgattgctat gaatctggga gaagaaatgt gacgcgtcat gcgaatattt tcgctgtttt
    16201 attcgatttt gctaacaaag accaacagca atcgatctta aagaatgtct tattgaatga
    16261 cactatcaca cagattacta ctccatattt caaattctat gaacaagatg ctttatgcaa
    16321 actcggacag acgaatatcg tctaccaaac gattcttgat tattggggag ggatgttatc
    16381 tcatgatgcg gtaactttct gggaagaata cgaccctact caaacaggaa atgaaaagta
    16441 cagtatgtat ggagatcctt atggaaaaag cttatgccat gcatggggag caagcccaat
    16501 ctatctttta ggacgctatt ttatcggttt gtatccaaca aagccaggtt atgaagaatt
    16561 tatgatacaa cctaatctag attcatttga aacactgaat tgtacgctac ctatcaaaga
    16621 tggaaagatt tcgcttgaaa aaacaaaaga taagatcgtg attacttctg atagaacagg
    16681 cggaacagtg aaaatgaatg gtaaaagtta tcctcttcta gcaaaacagc cacttgtctt
    16741 aacaagctat tcaaaaataa atgcataaaa caaaaaactg cttgcgacat atcagaagac
    16801 tttaaatctt cttctgatat tgtccaagca atttttattt tgaagtttgc ttaattctgt
    16861 tctttagaaa caatgtttgt tctttttccg gcaaaaagaa agctagataa tacgacaagt
    16921 aaaaagaaag agatgattcc aactgtcaag gctatttgac cgtattctcc tagtttccca
    16981 agtacaagtc ctggtactag ataatcagta tcggcaaatg tagaagaagc gattttaaga
    17041 tctcctaata ctggaaggat aaataatggc agccaactaa tcaataagct attgaaagca
    17101 gaacctaata ccgcccctct tctaccgcca gtcgagttgc cgaagacacc agaagcagct
    17161 ccgcagaaga aatgtcctac taccccagga atgataactg tagtttgcaa gcctatcata
    17221 gcaaacatgg atagtgttcc tacaaagaag ctaacaaaaa agccaattaa tacagcatta
    17281 ggtgcatatg gaaaaacgat aggaacatct aatgctggtt tagaatcggg tacgagtttt
    17341 ttagcaatcc cttggaatgc tggaacgatt tctgccaaca ccattcgaac cccttgaagg
    17401 acgataacaa acccagctgt gaatgttcca gcttggatca gtgcaaagat tacagcgttg
    17461 tctccattgc ttagttctct ttcaacaaat ccaggaccag ctaacaaagc aagtgcgaca
    17521 tatacgatcg acatcaagag catgatcgat acagtagaat ctcgcaaaaa gctgaaactt
    17581 ttaggaatct ttatgtcctc tgtagaacgg tctttgtttc caaaaaactt tccgatccat
    17641 ccactagaag cataaccgat atttccggta tgccctaacg caacttgatt gtttccagtg
    17701 atgttcttca taaacggttg acaaagagca ggcgtaatag ttaatagtgt tccttcgaag
    17761 accccgccta ataagatcat ccacaaattt gcagtaaacc ccgcgcttac taaaatgact
    17821 gctgttagac aagaaacata aagcattgct tgacctgtaa gaaaaatgaa tttatatctt
    17881 gtgaatctag caagtaaaat attcacgatc atccctacta gcatgatcaa agcagtaggt
    17941 gtaccgtatt gttgcaaagc aatcgccact actgcttcat tgctaggaac tactccttga
    18001 gtatgcagag ctgtttggaa catcgaagca aaaggggtta gtgaattact gattaaacca
    18061 gcaccgccga tcagtactag gaatccgaca aatgttttga tagttccttg gatcacttct
    18121 gaaaatttct tcttctgaag aacgagacca agcagtgcaa tcaaagaaac gaggatggag
    18181 ggctgactga cgattgacac aaacaaattc aacaatttat ccattgatag ttcctccctt
    18241 gaatcatttt tattcttttg acaagatctt cgttactttt tcttttactt cttcgctgtc
    18301 aatgatcgat tgcaaaggta cgagcttttc atcaggtata gaagttagcg tatctttcaa
    18361 agaatgctca atgaagaaat aatcagccat atcgctagat acacttccaa catccgtatg
    18421 acttacttca aactcgtcca catctgctcc aagatctgca agtgcttgtt tgatgttcat
    18481 ctctaccata aaacttgttc ctaatccact ttgacatact gcaaaaattt tcatatcatt
    18541 cgtctccttt tcttatgatc gctaatattt cttcttttgt tgatgcgtgt aataaatctt
    18601 gaagattttg tttattagaa agtagctttg ttaaatttgc caaagcccga agatgtgcct
    18661 cattatcgat agcagctaaa cagatgaaca aactaatggg atgggctgga ttatcaagca
    18721 gatccacagg ttgttgaagt ttcagcaaag acatccctac ttcgtttacg ccatcttctg
    18781 gacgagcatg aggtaatgcg atgtgatcgc caatatggat aaacgcacca tactgctcca
    18841 cgcgctcgat catagctttg atataacttt cttctatttt attttctgat aatagcggct
    18901 gtgcggcaaa tgtgattgct tcttgccagt tttttggttg atccgataat tggatcattt
    18961 cttctgttaa taattcagat agcataggac gttgatcctc cttcttttct aaaagtttgt
    19021 tcattttacg atttaatact tgatagagct tttcttcgtc tacgccttct tttaattcga
    19081 tataaggcag tagcgccgac aacaattctt gggcagaagg cattgaaaat cctggtatca
    19141 gccaatctct ttgtacttga ttgatcagct gatttttttc caagtcagtc atgattggat
    19201 gcagaacata gagagacttt ttcttatcag taagtgtgag aggtacagta gaaaaaataa
    19261 tatcgtaaga agtttcgtca acctcgtgta agcggtcagc tgaattagtc tctgtaaaaa
    19321 agatcatcgg gaataattgc tgaagttcac tttttaagat caatgaagag ctaatgccac
    19381 ttggacagac gatcacggct cttatttttc tatttctttc ttctgcgtcc gcttttctga
    19441 tctctccgcc aaatagtata gtgaaaaaac caatctcttc ttcagggatg ctcttcccta
    19501 ttcgtctttc taacggaagt aatgcttttc ttgtcatttc gtagatggaa gcatattgat
    19561 gcttaatttg atcgatcatc acattaggta aataaaaaga ataggaaata cgaaaatagg
    19621 cagggaccaa gtgataaaag acattcatca ataattcacg aaacgaagca aattctacgg
    19681 ccatcaggaa ttccatgcga tggatgactt ctgaagaaca ttccagcaaa aaatcaagtg
    19741 caggctcctg gacatctcct tcaacgatcg atgctaagca aagagagaaa aatataatct
    19801 ccgaattttg atgttcggaa tagccaaggc cagtcaatac ttgtcgacta atgtcagtga
    19861 ctgcaagaga agccaacagt tcagcatctt ttaccagttc catggatgtt tttccaattc
    19921 gaatggttgt caaactcaaa taataagcta attcatccat tcgatttggt gcgaatcgaa
    19981 gatctgatag tgaaatcgtt ttatctagca aatctctaac tttggcgtaa taatcaatgg
    20041 aaagggttgc ggttaaatac gtgagcccaa atcttccagc aagtgactgc atcaaacgag
    20101 cagtgcgatt ttttgcttct cttcttaata ttgcttctga ccctagcagc ctaaaaccag
    20161 ttttcctagt atacgacagc tgacaatctt ccacttctaa ttcatttctt atctttttga
    20221 tatctgacag gactgtccct ttagaaacct gaagaaaatc ttgaaaatga aaaacagaaa
    20281 cagacgttgc agtcgaataa accatcaaat aaagaagatc tcttcgctct tgttcggtat
    20341 acacagcttc aaatcgagta atatccaaaa atttttctgc ccagtcgatt gctcggaatt
    20401 tctttatacg gatacgggta tcatccacat attcggcaaa aggagttaat tgtttgatcg
    20461 cctcgcttgt atttacttcg atgatctctg ctgctttttc tagactgatt tctcttggtg
    20521 ttttcaggag ataactaatt ttgtagttca cagcgctgtt cacctcctac ttatattcta
    20581 gtatggtagc gcttttaaat cgaggggtgt ttggtacaac ttacagttgg atttttttta
    20641 cgactgtacc gaacgatttc tatcgaatgg atacagaaaa aaagcaggtg accaaatgtc
    20701 tcctgctttt atgaattgat ttcgtccgat caatgatgat catgtttatt ttttgaggtc
    20761 agttcttcaa atttttcttt gacatcttca accgcttttt cgatatcttt ttcaaagtga
    20821 ttgggctcat taggctttgt ttcctcttct acagaatttg aaccagataa agctgtttct
    20881 ttattttctg tttcaccaga gtttgtgcca gctaatgatt cttctttgtc ttctgtttca
    20941 ccagaattag ttcctgctaa agccacttct tcttctgttt taggggccat tgaacctctt
    21001 aatcgtttgt gtttttcacc gtcataattt gtcatgttgg ttcctcctag tagttctata
    21061 ctttttcatc gtacaataag acagtttatg cgtcaaaaaa caaacccgat tcttacaaat
    21121 atgtcatatt tttccttctg attcttgaat gcttttgatt ccttcttcca aaattttcat
    21181 ttgtaagatt gtttcttcat ctttgatgac tttttctgcg ccattaacta atgtctcgta
    21241 aatcccttcg tagacacggc tgtaatcacc aacctcggaa attacttttt cttcatgata
    21301 actcccttgt tcatctatat aggtcaatac accataatgt tcgggcaaat cgataccaaa
    21361 gtcttcatga tcaggcatgt aaaacatttt cagatgttct tcttgtcgat cttttgtttg
    21421 tttcacgaac atcccttttt ttccgtaaac gacgaaactt ggacgttctt tgatgcggaa
    21481 ataactggat tttatcgaaa ttttcatatt tccatagaaa aaatccagat cgaagtaatc
    21541 attcattcgt cctttcccta aaagttgacg tacatcatag ctgatatcat ctggttcgcc
    21601 gaaataagaa agaacttgat ctactgtatg acaagcatgt ccatataaat agctgttcgc
    21661 agtagaaaat tcatgcgtat tttctggtac ttccggtctg aaataatcat aatgcatttc
    21721 tacttctaaa atatccccta attttccgct ttcgattact ttttggactg tcaagaagtc
    21781 agaatcgaac cgtctgtttt ggtaacattg gataaataga cctttttctt ttgctaatgc
    21841 aaataactct tctgcttcct ttgacgtttc tgcaaaaggt ttctctacta gtacattctt
    21901 accatgttcg agtgccattt ttccatattc ataatgaaat tgactaggtg tagtgatgac
    21961 aactaattgg atctcaggat catcccaaag atcagacagc tgatcagtat attcgatgtc
    22021 ttcgaatgtt ttccacactg gttcagatgg ggaaaaaatt tttttgatat tgattttgtt
    22081 cgtaagtttt cttgaaaaag gcaaatgata gcgatttgta ctctttccat tgccaagata
    22141 agcgattgta agcatgagtg gtgcctcctt ttattgatgt tttcagtata tcctagaaaa
    22201 gcgcagaaag tatttataat agctattctg gtaaaaaagt tcagaaaaac acttgttatc
    22261 attcggtttg gtgaaattaa tgttcaaagt aaggataaaa atcaaaaaga tagtagcgga
    22321 accaagtgtt tatcagtaag atagaatttg gaggtcagat catgcttatt gaagaaaaac
    22381 taacaaaaca agagttgttt accacgacag agaaacggat tgtcgattac atccgtagga
    22441 atatcgaagc tgcagtctac atgacgattg aagaattagc aaaagctacg tatacttccc
    22501 attcagctat cattcgttta tgcaaaaaaa tgggattcag cggatttaaa gaattccgtt
    22561 tcgagctggg gcgggaagtt catcaattga ttgctcagtt caatcaaacg attgatccta
    22621 attttccttt ttcaagtgaa gatagcactc agcaaattgc aaagaaaatg gcggatttat
    22681 cgatccagtc aataaaaaaa gcacaattgc agattgaaca tgaagattta gatcaaatcg
    22741 gtaaagtatt gaacaaggca cagcgaatct ttctttttgc aaaaggtgat tctcaaatca
    22801 cggcaaggaa attccagaat aaaatggtca agttgaataa gtttttgatc atggctgaag
    22861 aatacagtga ttcttcttgg aatgcagcca atttgactag cgaggattgc gccattttta
    22921 ttagctacag cggtcgcatc catcattatg aacgaataat gacctatttg aagcatgtag
    22981 aggcccctac cttgctgatt accggaaatc agcattcaga aatggccaaa caggctgata
    23041 tgtgtcttgt tatatcgcag gaggaatatg attttgctaa agtagcgact ttctcctctc
    23101 aaattgcctt cgattacgta ttaaatacgt tattctcagt gatatattct caaaattttg
    23161 aagagaatat ccgcaacttg aaaaacaaac aagaattgat gcaaaaaggc cttcttaaag
    23221 aatatcggaa aacttaagaa aagatcctca tttagtaata agaaagatag tgtttgatag
    23281 gctctctttg atatcatcat aaaaacaggc tgaagttttc tttttcaaac ctcagcctgt
    23341 ttgtttacgg aacgattcga atagatatat tatagaaatg aggaatagct aacttctgtt
    23401 tcttattttg aacgattgac gaaaaagata tataagaagg aggaaaatca gtatacatgc
    23461 agctaacaat ccatacagga aaaatcgttt gttctcggat actttctgta cttctttttg
    23521 aacttctttt gcatgataag gaacccggtg ccctctgaca agtaagcgat gactgttgac
    23581 catataaggt gtacaagtta ggagtgtcac gaaatcctgc cctttttcga ttctcagatc
    23641 ttttgtatca gtcggttcta ccgtcttgat ctgatcgact tgataagcga gtgtccgtcc
    23701 attgatttcg atatagaaag aatcacctaa agtcagtttc ggtaagtctg tgaacaactt
    23761 tgcttgaggc agtcctcgat ggctggaaat aacgg
//
LOCUS       DAXQKX010000040        23575 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.040, whole genome shotgun sequence.
ACCESSION   DAXQKX010000040 DAXQKX010000000
VERSION     DAXQKX010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23575
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.040"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(460..1089)
                     /gene="udk"
                     /locus_tag="ACF3MF_001778"
     CDS             complement(460..1089)
                     /gene="udk"
                     /locus_tag="ACF3MF_001778"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HFE3927764.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1173..1868)
                     /locus_tag="ACF3MF_001779"
     CDS             complement(1173..1868)
                     /locus_tag="ACF3MF_001779"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HFE3927765.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1881..2597)
                     /locus_tag="ACF3MF_001780"
     CDS             complement(1881..2597)
                     /locus_tag="ACF3MF_001780"
                     /EC_number="5.4.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0140098 - catalytic activity, acting on
                     RNA [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HFE3927766.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2927..3532
                     /locus_tag="ACF3MF_001781"
     CDS             2927..3532
                     /locus_tag="ACF3MF_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0008097 - 5S rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HFE3927767.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3857..4180
                     /locus_tag="ACF3MF_001782"
     CDS             3857..4180
                     /locus_tag="ACF3MF_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HFE3927768.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4362..5732
                     /locus_tag="ACF3MF_001783"
     CDS             4362..5732
                     /locus_tag="ACF3MF_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFE3927769.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5862..7163)
                     /locus_tag="ACF3MF_001784"
     CDS             complement(5862..7163)
                     /locus_tag="ACF3MF_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HFE3927770.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(7393..9384)
                     /locus_tag="ACF3MF_001785"
     CDS             complement(7393..9384)
                     /locus_tag="ACF3MF_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HFE3927771.1"
                     /translation="MATTHNTKKISMAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGL
                     SGINPDFVIGSVSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLII
                     PAMIGGAALLADGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFM
                     VQRFGTDIVGKAFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKL
                     GLFILGNIFLATTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQN
                     PEAQQIKNLNPFFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPR
                     LKIMYPGNSIGQMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALL
                     YFYLIQNGHSRWLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWE
                     QGNIIRESSTEDVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSI
                     LDKRPKRARVYWFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQ
                     VIHDLMKQGRLPKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAI
                     KKIATSPETWFGLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9528..9794)
                     /locus_tag="ACF3MF_001786"
     CDS             complement(9528..9794)
                     /locus_tag="ACF3MF_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFE3927772.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10304..12430)
                     /gene="pnp"
                     /locus_tag="ACF3MF_001787"
     CDS             complement(10304..12430)
                     /gene="pnp"
                     /locus_tag="ACF3MF_001787"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HFE3927773.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12618..12887)
                     /gene="rpsO"
                     /locus_tag="ACF3MF_001788"
     CDS             complement(12618..12887)
                     /gene="rpsO"
                     /locus_tag="ACF3MF_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HFE3927774.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13138..13701
                     /gene="def"
                     /locus_tag="ACF3MF_001789"
     CDS             13138..13701
                     /gene="def"
                     /locus_tag="ACF3MF_001789"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFE3927775.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(13954..14475)
                     /locus_tag="ACF3MF_001790"
     CDS             complement(13954..14475)
                     /locus_tag="ACF3MF_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HFE3927776.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14478..15320)
                     /locus_tag="ACF3MF_001791"
     CDS             complement(14478..15320)
                     /locus_tag="ACF3MF_001791"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HFE3927777.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15313..16038)
                     /locus_tag="ACF3MF_001792"
     CDS             complement(15313..16038)
                     /locus_tag="ACF3MF_001792"
                     /EC_number="2.3.1.286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0034979 - NAD-dependent protein lysine
                     deacetylase activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HFE3927778.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16214..16510
                     /locus_tag="ACF3MF_001793"
     CDS             16214..16510
                     /locus_tag="ACF3MF_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927779.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     regulatory      16766..16940
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            17078..18670
                     /locus_tag="ACF3MF_001794"
     CDS             17078..18670
                     /locus_tag="ACF3MF_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015837 - amine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFE3927780.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18683..19423
                     /locus_tag="ACF3MF_001795"
     CDS             18683..19423
                     /locus_tag="ACF3MF_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFE3927781.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            19591..20940
                     /locus_tag="ACF3MF_001796"
     CDS             19591..20940
                     /locus_tag="ACF3MF_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFE3927782.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(21068..21658)
                     /locus_tag="ACF3MF_001797"
     CDS             complement(21068..21658)
                     /locus_tag="ACF3MF_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HFE3927783.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVIVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            21805..23157
                     /gene="brnQ"
                     /locus_tag="ACF3MF_001798"
     CDS             21805..23157
                     /gene="brnQ"
                     /locus_tag="ACF3MF_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFE3927784.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         6754 a         4746 c         4489 g         7586 t
ORIGIN      
        1 agggggtgcg acaaaagagc ttcttcaaaa aaataagtcg aaatctcaca caaattcgag
       61 aaataatttt cgtaagtttc ttcttattta ttgcatctga ccacttctgt tacaacctct
      121 cgttaaacgg tgttcaaaag cttgcatcta cgataataag cccaacccaa cgaaaaacgt
      181 gaggagctgt tttatttgga tgctcttatc gcttgatgca aagacagctt ttttacaacc
      241 tctacttcac ggtgctcaat cagctgacct tcggtattag ctcaaaaaac ggtaaaatat
      301 aaacagctat tttccgtttc ttctttttaa tacttaggtc aagatgctgt tttcacaacc
      361 tcttgttata aataaaaaaa cagttggctg gtgactgttc aaaaagcaga atccttgctt
      421 ttcaaacggt cgcagtccgt tcaactgttt cgctgcgcac tatttatggt ttaagaaact
      481 agctactttt gttgtaatca aatcaatagc aacgtggttt tctccgcctt ctggaacaat
      541 gatatccgca tagcgcttcg ttggttcgat aaattgatga tacatcggtt taacaactgt
      601 caaatattgt tcgatcacgg agtccaatgt gcgtccccgt tcttccatat cccgtttgat
      661 acgacgaatg atacgaatgt catcatctgt atctacgtat actttgatat ccatcaagtc
      721 acgcagacgt tcgtcttcta aaatcaggat tccttctaga atgatcactt cttttggttc
      781 ctgaatgatc gttgcctgac ttcttgtatg cgctacatag tcatacacgg gtttttcaat
      841 ggctttatag ttcagtaagt cgcctacatg ctgaatcagc agatcattat caaaggcaaa
      901 tgggtgatcg taatttgtgt tcaatcgttc ttcaaaactc aaatggctct gatccttgta
      961 ataagaatct tgttcaagca tcatgatgga atggtccggg aagttgttga aaatcgcacg
     1021 gctgacactt gtctttccgc ttccggatcc acccgtcaca ccaatgataa ttggcttgct
     1081 ttttgtcatt gactaaaacc tctttcgtat ccgttttttc attctaatct attatagcga
     1141 aaaaacacga aaatgctata tttttctgaa aattaatcct tttcaatttc caataatgaa
     1201 taaagttcct ctaatgaatc gattcgataa gtaggctgga tttcttcgat ttctggtaat
     1261 ttatttctat tgaaccaaat cgtatcgatc cctgccatat ttcctccttt gatatcagaa
     1321 gtcaaagaat caccaatgat cacagtttgc tttttatcaa aattaggaat gtgggaaaag
     1381 acatgatcaa aaaattcttt catcggcttt tgcgctccga cagcttctga gacaaagata
     1441 tccttgaagt aatcaagcat tcctgcatct gttaatcgcc gatgttgcgt gtgcgacaca
     1501 ccgttcgtca caatataaag atcagcatgc ggatggacct ttttcaggat ttctagactt
     1561 cctggaacaa gatcatgacc ttggttcaag tagtggcggt agcgtttttc catttgatca
     1621 ctatctactg ttttcccaaa ttgctggaaa agtaacccaa aacgactgcc tattatttct
     1681 tctcgtgata gtctgccttt ttcaaactcc tgccataaat gatgattcaa agccttatag
     1741 ctggtttcga tttctggtgt caatgtgatt ccttgttctg caaacaaagc acttaaagca
     1801 ttggcttcag ttaattgaaa atctaacaat gtatcatcta catcgaacaa taaagtttta
     1861 tatttcatct ttttgacctc ctatttaaaa taaatactta actttttcat ctctgctaat
     1921 gtcaacgatc gatactcgcc tactcctagc tgttcatcta attccaatgg tcccatgctt
     1981 agccgtttca atgcggtcac tttctttcct tgggctaaga acatcttttt gacttgatgg
     2041 aattttcctt cttggatcgt caataaaacc gtactttggt gcttgtctgc tttgagtatt
     2101 tttaaatcag ccggcttaca ttgataccca tcagcgaata cgattccatt ttcaaatgct
     2161 gttacgtctg ccggtgtcac cctttcgttc acaactactt gataagtctt tgaaaccttt
     2221 ttttctggaa gtagcatttc atatcccaat tgtccattcg aagtgatcag caatagtcct
     2281 gttgtatctc tatctagtct tcccactgga tataatggtt ggaaacgatc ggcacttgca
     2341 atcagatcga ttactgtcgt cttttctgga tctgatacag ctgtaacagc tttttcaggt
     2401 ttattgagaa gataatagga ctcatttgtt tctaagtgtt cacctgctac ttcgatttga
     2461 tgcagtaaac tatctacatt tcgattttgt cgaaattcga ctgtgccatc tatcatcact
     2521 tgcttcaaag caaacagccg cttcatttcc ttgcgtgtcg tttctaattt ttcttctatt
     2581 aatttatcta aacgcatgct gtttcctttc ttattactac taattaatta taccttgaat
     2641 attcttgctt gcaaatacat catcatagtt attccttgac ttaattaaca gttcacgtta
     2701 cggttaaata ttaaagtgaa ttggatttct catacacagc gtaatgacct ggtggagaaa
     2761 agttgaatcc tgactttcta aggggagatg cgcgcatctc tccttttgcg cttttttaag
     2821 cgccctgcct tcgatgatgt gcacgagatt agcctttaga attcacttaa ataaaatctg
     2881 tccgttacca aagcagacag tcacatttta aggaggaatt ttggttatgt cagtatcatt
     2941 agaagtaagt aaaagagaag tacgtccccg ttcattaaga aacaaacttc gtcacgaagg
     3001 gaaagttcca gctgttgttt atgggtataa agtagaaagt acccctatct cattcgatgg
     3061 tttgacacta agcaaattgt tgcgtgaaca tggagcgaac acagtcatca cgatggacat
     3121 cgatggacaa aaagtcaata cattggttca caagatccaa acgaacactt ttaccaatca
     3181 tttcgaacat gcagaatttc tatctgtaaa catgtcggaa gaaacagaag tcgaaacaga
     3241 agtcgttctt gttggcgaat cagtgggtgc taaatctggt ggagtgttag ctcaaaactt
     3301 gtatacagta gtcgtatctg ctacaccaga caaattgcct gaacgaattg aagttgacgt
     3361 gacaaacttg gaattaggtg attctattac agtagccgat cttccaaaaa acgacgatta
     3421 caaattcgtg accgacagtg aagagcaaat cgctgctgta gtcgctcaaa gtgaagaaga
     3481 aagcacaggt gaaggtggcg aaccagaagt gatcggttca acagaagaat aatactgaaa
     3541 caatcaggtg gtgttagaag cggcgggtca gcagctttta acacgccttt tttatttcta
     3601 atcgtttatt ttcatatggg gcttccactt ttgtaaatgg ctttacaaac gaaaaatcct
     3661 aatttaccaa gcttttcctc gcatactttt atcgtacctt tataaaaatt tatactttga
     3721 aaaaaagtat tcaattattg ttgcattttt cctgattctt tattagaatg aaccctcgtt
     3781 gaagtaagta tttctagttt atcctaggat taattataaa aataaaacat tcgttgattc
     3841 gaaggaggtt aaacagatgt ttgaaagttt tgatagcagc cgcaaccgtt acgcttcagt
     3901 tggtgtcgta tcaagtttgc cagatgaatt gattgacagt atatggttta ttattgacct
     3961 agatcttaag ggagtcattc cattagaaaa tatattaacc tttgatttga tcgaaaatcg
     4021 tggaaaagtg acgatgcatt tttctcaagc aggaagcaat gtggaaatgg atattgattt
     4081 gccgtttgcc tattcgaacc aatttcctgc tcaagtatac gcctatgatg acggtacgag
     4141 agaaacgatc cttttaccaa gtgagattag acaatattaa ggtgatagat aaacgtggat
     4201 gtcccttatt ttacagacca ggccaagttg ttgattcttt gactcaattc ttggcttctt
     4261 tttatggagt ttcataaatt atcattgatt tctaattggt attctcagga taaacgctat
     4321 atactactaa ctaaatttta aagatataag gagtttaaaa gatgcgcgat ttaacaaaag
     4381 gaagccccgc taaactgatt ttgatgttca ctgttccttt actgatcgga aatgtttttc
     4441 agcagttcta caatatgatc gatatgatca tcgtgggtca gacgctaggt aaaaatgcgc
     4501 tggcagcggt tggtgcaact ggaagcctga catttttgat cattggcttt gcccaaggtt
     4561 taacagctgg tttagccatt attaccgcac aacgttacgg tgcaaaagat tatcggggtc
     4621 tgaagaaaag ttttgctgct agtgttgtca ttagtcttgt cgtcactgtg attttaactg
     4681 tcctaagtct cctgtttatt cgtccgatgc ttcaattgat gcaaactcct cctgaaatac
     4741 ttgatcaagc acaaacattt atttcaatta ttttattagg gatctttgca tcagtcagtt
     4801 tcaatttgct ttctaatgtc attcgcgcac ttggtgacag ccgcacacca ctattctttc
     4861 tgatcattgc ggtcatcatc aacgtcgtac ttgatttgat ctttattatc tattttggca
     4921 tgggtgtgga aggtgcagct attgctacag taatcgcaca agtttcttcc agcgtactgt
     4981 gtctagtgta tatcaagaaa aaaatgcctt tgttacagtt acgcaaaaaa gatttcaaat
     5041 ttgaaaaaga agagtttgct gtacacctaa atgctgcttt gccaatggcg tttcaatctt
     5101 cgatcatcgc tgttggtgct atcgtgttac aagcagcact aaatagtcta gggacagatg
     5161 tcgtagctgc tcaagccgct gctggtcgta tcgaccaatt tgcaaatcag ccgatgatgt
     5221 catttggtat tgcaatggca actttcactg cacaaaacta tggtgcgaaa gaatatggcc
     5281 gaatcttgca aggggtacgt caaactttac tgatgagtgt cggatttagt ctcttagcag
     5341 gtgctatcgt cattttcttc ggtcatttct ttgttcaatt gtttgttagc ccatcagaaa
     5401 cacgtgtatt tgaattagca caaacctact tcaatatcaa tgggtctctt tactggatct
     5461 tagcagtcct gttcatttta cgctacacac ttcaagggct tggacaaagc aagatcccta
     5521 cgatcgccgg tatgatggaa ttgcttatgc gttcttttgc agctatcgtt cttacaggaa
     5581 tgtggggata cccaggagca gcagcagctt ctcctttagc ttggatcggt tctgttgccg
     5641 tgttgcttta ctcttatatg cgttcgatga aacaattgaa acacatgggt gaagaggaac
     5701 atttcacatt agaacatgca gaagcaagat agccttgatt aaaagaaatc gttgcggcta
     5761 aaaatgaaaa cttttattga aaatatcttc ttcgtttacc gaaaacaggt tttttagata
     5821 acaaaaaggc tgtgacaaaa aatgtcacag ccttttttct tttattctat ttttctttcc
     5881 gtggactcta ctttgaaata atcgatatgt gcatgctggt attctaatac cgtgaaacgg
     5941 aatgatgcaa tctcaatgat tgttcctgct tttatttctt tatatcggct agaagcaaag
     6001 cccgcaagtg tagtaaaatt cgtttcttca aactctggaa tctctacatg aaaataacgc
     6061 tggaaatcat ctaatgttag tttgccggag atgatataag agccatctga ctgttccgct
     6121 atcaatgctt cgtccaaatc tgtctcatct cggatttccc cgacgatttc ttctaaaata
     6181 tcttcaatcg tcactaagcc gcttgtccct ccgtattcat cttttaagat agcaatatgc
     6241 tttccctttt ttcgcatgat cgtcaataat ttttttatag ggatcgtttc agttgttacg
     6301 atcggctctt caatcaactg ttctactgtc agctggtcat ctttataaga ttgcttgatc
     6361 aaatctggca aggtgacata acctaaaaca ttgtcttttg attctaagat aaccggatag
     6421 cgagtatgtc cttgttcaat cgaagctttt atcgcttctt tgacggtttc tgaagcttcg
     6481 aatacttgca tggacgtacg gtctacttgt atatcttttg ccaaggtatc atcaaattca
     6541 aacacgtttt ccaaataatg atattcttct ttggtcaact ctcctttttc ataagaattc
     6601 aatgcgacta atgtcagctc ttcttgagac aatgtctctt ctccttcaga tacgagacgc
     6661 acacctaata gcttccctag ccctgcagct gaatgattca atacccaaat aaaaggaaac
     6721 attactttat aaaaataatg aagtggttta actacgaaca agacgacctt ctccgtattg
     6781 acgatactat agctcttagg aagcagttcg ccaataacca catcgatata cgtaactaaa
     6841 ataaatccca gcgccacaga gattgtactg ctaatagccg aactaaaagg tagtttaccg
     6901 atcactggtt ctagtaaagc cgcgacagat ccttcaccga cccacccgat gatcaaaccg
     6961 gttagcgtaa ttcctaattg actagctgat aaatagttat ctaaatggtg tgtaacatga
     7021 agagctagct tggcgttctt tacattttcc ttttctagtt gttccaatct tgatcgtctg
     7081 attttcacta aagcaaattc acttgctaca aaaaatgaag taattgcaat catcaaaaat
     7141 aaaataatga aattgataac catattctcc cgcctttctc tttttctatt gtaccctttt
     7201 tctacaaaaa gattgaaaat aatgcgtatt catatttagg aataaaaaag gagatgcggc
     7261 atttttcagc cacatctcct tatcacttca aaatcattgc gttacttgtt gctaaacagc
     7321 tttttcatga cctctgataa acggtgttca agtagctgac attcgacatt agttcaggtc
     7381 aaagcgctac tttcacaacc gctctttcaa ccatgttttc cgagtatttc caatgataag
     7441 cggaacagtt tcatgtttta cttcgctgta ctctagccca aaccatgttt ctggcgaggt
     7501 agcgattttt ttgattgcca gttttgcctg catgatttga cgttgccatt ttcctagagt
     7561 tgtcacattg gaaactactt catcaatcag gacaaattgg aaatcgccaa cttctcgccc
     7621 tggtgtcaga gagtatcttt gtggctgttt tggcaaacgg ccttgtttca tcaaatcatg
     7681 gatgacttgg cgaacatata cgttgatttc ctgttggacc ctgaaaccta agaacagatt
     7741 cacttggaca ataaaatcag tgtccatcat atctacttga tattctttcg tatatggctc
     7801 atccgtcact tccacatgaa caaaccaata gactcgtgct cttttaggcc gtttatctaa
     7861 aatcgaatag atgaactgtc ggccaacttt atcttcagcc atatcaggaa ccaagaagac
     7921 cacatttgtc tgatagattg gtaaagaagt atcatcacgt aattctctaa gctgcgggat
     7981 ataatctctc aaagacacat cctcggttga cgattcgcga ataatgttcc cttgttccca
     8041 aataaacatc acgactaaga tgatcaaacc aatcagaacg gctacaaaac cgcctcggaa
     8101 gaatttgaca acacttgaga taaagaaaac gacttctatc gcaccgaaga aaaaggtaac
     8161 taaatatgca agccaacgag aatgcccatt ttggataaga taaaagtaaa gcagtgctgt
     8221 tgtcatcaac atcgtcacag tgatcgatag accgtaagca gcttccatat gatgagacgt
     8281 tcggaatgtg acaaccacta gagaacaggc gatccataaa atcagattga ctgctgggat
     8341 atacatttgc ccgatactgt tcccaggata catgatcttt aaccgaggca gcagtttcaa
     8401 cttgattgct tctgaaacta gcgtaaacga acctgtaatc aatgcttgcg aagcaatgac
     8461 tgcagcgact gttgcaaaag caacgccgat cacgatccaa ctttgaggca tcatttggaa
     8521 gaatggattc aggttcttga tttgctgtgc ttcagggttt tgataaacat tcaacaacca
     8581 cgcagcctgc ccaaaataat tgataaccaa acaaattttg acgtaaggcc agctcagacg
     8641 aatatttcgt ttgccgacat gtccaagatc ggaataaagc gcctctgcac ctgtcgtagc
     8701 caggaaaata tttccaagaa tgaacaagcc taatttgtta tctgcactaa aaagcagctg
     8761 gatagcataa taaggattca gtgcacggat aactgtccag tcttgactga agttcattaa
     8821 tcccattacg cctaaaaaag taaaccaagc gaacatgatt ggtccgaatg cttttccgac
     8881 aatatctgta ccaaagcgtt ggaccatgaa taaaacaaaa ataataacta aagtgataat
     8941 gacgatcacg ttctggttat taccgaaccg gtcaaaaaac tgcggaattc ctcgcaagcc
     9001 ttcaatcgca gtcgttaccg tcacagcagg ggtcaatacc ccatctgcta gtaaggcagc
     9061 tcctccgatc attgcaggaa tgatcaaata tttcccacct tttcggacaa gtgtgtagag
     9121 tgagaaaatt ccaccttcac catggttatc tgcattcaat gcaatcacga catatttgat
     9181 tgttgtcagt agagtcaatg tccaaaaaat caatgagact gatccgataa caaaatcagg
     9241 attgattcct gacaatccgc cattatcttc aacaatcgat ttcataacgt aaagcggact
     9301 tgtcccgatg tctccgtaga cgactcccat cgctacaagc aggccagcca ttgatatctt
     9361 tttggtattg tgcgttgttg ccacgttttt ccctcatttc ttgttatatg gatatccttt
     9421 aggtaagctt gaatgataga tgatattctt atccatgaca cccgctttcc taaattgctt
     9481 ctaattatcc aagtaacaca ctgaagtgtc aacttatttg aataaaatta ttctttcttt
     9541 ggacgttctc tgatacgtct tgccacaaat gaataaagag caaggcaaaa aattgcaccc
     9601 aataatgctg gtatcaaata aaaaccgccg agttccggtc ccagtggtcc tagtaaaaat
     9661 tcgccgagcc aactacctaa aaaaccgata atgatatttc cagatacgcc tcccgggact
     9721 tcctttccta aaattgcgcc agctatcaaa cctaatatac cgccgataaa taacgaccat
     9781 aaaaaattca gcatctcctt tccctccttt atccatattt ctcactttta ttttacgctt
     9841 tattcagaag gactccaaaa atatgcgcca agaaactcca gaaaaaaaga agttgtaaca
     9901 aaagtgttca gcttatttcc gtagaagctg cttctggaac accgtgaatc agaggttgtg
     9961 aaatcagcgg tttgacctga gtattagaga aacaaacgga aaaatagttc ctcatatttt
    10021 gccgtttttt gagctaatat cgagggacag ctgattgaac atcgtttatt ggagaggttg
    10081 taaaaaagct gttctgcatc aagtaataag aacagccaag taaaaacagc tcctaatgtt
    10141 tttaacttgg ctggacttat taccgcagat gcaagctttt gaacaccgtt tattcgaaaa
    10201 aaaaggactg tgacacggct tttgtcacag tccccttttt tcgaataatt attgtccccc
    10261 tgtcaccttc acgatcacaa gtacattatt cctatgaatt aaattatttt tcttcatttt
    10321 tcgttgaacc atcttcgttc aacattgctt ttcttgacag atttacgcgt ccttgtttat
    10381 cgatttcagt tactttcaca aggatctcat cacctagttt aacaacatct tcgactttat
    10441 tgacacgatc gtttgctaat tgggaaatat ggacaagtcc atcttttcct ttgatcaagt
    10501 tgacgaatgc accgaatttt tcgatacgga caactttccc tagataaact tcaccaactt
    10561 tgacttcttt ggtcaaatct tcgatgatct tgatagcttt tttgatcatt tctgcatcag
    10621 ctgaagcaat acttactttt ccatcttgat cgatatcgat tttcacacca gtttcatcga
    10681 tgattccgtt gatcgtatcg ccgcctttac cgataacatc tttgatttta gcaggttcga
    10741 tctggatcat ttcgattttt ggtgcatatt ggcttaattc ttcacgtgga gcagcaatcg
    10801 ttgaagtcaa ttcttctaag atttccatac gtgcttgttt tgcttgagtt aatgcttcag
    10861 ttaggatttg ttctgtgatt ccttgaatct tgatatccat ctgtaaagca gtgataccat
    10921 cttttgtacc ggcaacttta aagtccatat cgccaagatg atcttccagc ccttggatat
    10981 cagttaggat cgtatagttt tcaccatcag aaacaagtcc catcgcaata ccggcgactg
    11041 gcgctttgat tggtacacct gcatccatca atgctaatgt gccagcacag atacttgctt
    11101 gggaagaaga accatttgat tccaatactt ctgctactaa acggatcgta taaggaaatt
    11161 cttcttctga agggattact tgtgctaacg cacgttcacc taatgcgcca tgtccgattt
    11221 cccgacgccc tggagagcct gcacgtcctg tagaaccaac agaaaattga gggaaattgt
    11281 agtggtggat gaatcgtttg ctgacttcca cccctaaacc atcaatgatt tggtgctctc
    11341 ctagaggtgc gagtgtacaa gctgataaag cttgtgtttg tcctcgtgtg aacaaacctg
    11401 atccatgtac acgtggcaat aagctgacct ctgatgacaa tggacggatt tcatccaatt
    11461 tacgcccgtc aggacggatc ttatcgatgg tgatcaattc acgtacgaca tctttttcaa
    11521 gatcttctgt gatttgttta acttctttca acaagtgatc ttcatcttca tgacctgcaa
    11581 atttctcagc ataagcttcg cggatatcga tcttcacctg ctcgatatta tcttcgcgag
    11641 caagtttttc ttcagtcatt actgctgctt tcattgtagc gtaagaagca tcaaagattt
    11701 cttttttcaa tacttcatca acttgcagta aagtcacttc cattttttct ttccctactg
    11761 cttgaacgat ttcttcttgg aaagcaacta actctttgat agcgtcaaaa ccaaacagca
    11821 atgcaccaag catgtcttct tctgaaactt ctttcgcgcc gctttcaacc atattgatgg
    11881 cttgtttcgt tccggcaaca gtcaattcga tatctgtttg ttctgcttgt tctactgttg
    11941 gattcaagac gtactcgcca tttacacgac caacttctac gcctgcgatt gggccgtcaa
    12001 atgggatatc tgagattgat agtgctaaag aagaacctag cattgctgcc atagctggcg
    12061 agcagtctgt ttctacactc atcacgatgt tcgttacttg gacttcatta cggaagcctt
    12121 ctgcaaacat cgggcgaatt ggacggtcga tcaaacgggc agtcaatgtt gcttccgtac
    12181 ttggacggcc ttctcgtttg atgaaacctc cagggatttt ccctgctgca tacatttttt
    12241 cttcataatt gatcgttaat gggaaaaagt ctgtatcttt tgcttcttta gaggccacag
    12301 ctgcacttaa gactactgta tctccataac ggactaaaac ggctccgttt gcttgttttg
    12361 ctagctgacc gacttcgatt tgtaagggac ggccgcccca tgtcgttttg aatacttgtt
    12421 tttctgacat aacttctcct tttccttctc gtgaaagcaa gacgctacta aacaaatgaa
    12481 aactgccgaa agccgtcttt tgagcagctt tcatttggtt agtaggagtc catctagctt
    12541 gatcacggaa ttttacttaa ttgatatacg agtaaaaaaa gtgagattca tgtgaatccc
    12601 actctttttg actaaaatta acgacgcaag cctaaacgtt tgatcaattc gcggtaacgt
    12661 tgaacgtcag ttttacgtaa gtaagctaac aagttacggc ggtgaccaac ttttttcatt
    12721 aggccgcggt atgaatgatg gtcttttttg tgcacgcgtg catgttcatt caagtggttg
    12781 atttcttcag ttaatacagc gatttgtact tctggagaac cagtatcccc ttcatggcga
    12841 gcgtattcgt tgatgatttc attcttgcgt tcttttgaaa ttgccatttc tttcacctct
    12901 ttcgattatt cccctgcgac tgagtaaaac gttggtgatt cgcttaacca agtggcaggt
    12961 catgtgccta gagcacacag ctatacttta cctgaaaccg ggttgaaaat caagtagtta
    13021 atcattaaga aaaggtagtt ttcaaacaat cttactacta cttttccatt tttgtggtaa
    13081 actataatgc gaaaatagac ttgaaacaca gtcttttaag aaaggggtac atattccatg
    13141 attacaatgg atgatatcat tcgtgaagga aatccgacct tacgcgaagt tgcaaaagaa
    13201 gtttctcttc cattaagcga agaagatatc tctttaggaa aagagatgct tgagttctta
    13261 aaaaacagcc aagatccaat caaagctgaa gaactacact tacgaggcgg tgttggctta
    13321 gctgctcctc aattagatat ttctaaaaga atcattgctg ttcacgtacc aagtcctgac
    13381 ccagaggcag atggaccttc tctaagtact gttatgtata atcctaaaat tttgagccat
    13441 tctgttcaag atgcttgttt aggggaaggt gaaggctgtt tatctgttga tcgagaagta
    13501 ccaggatatg ttgttcgcca tgccaaaatc actgtgtctt attatgatat gaatggtgaa
    13561 aaacacaaga ttcgtttgaa gaattatgaa tcgatcgtcg ttcaacatga aatcgaccat
    13621 atcaacggtg tgatgttcta tgaccacatc aacgatcaaa atccatttgc actaaaagaa
    13681 ggcgtattgg tgatcgagta gagaattggc aggttccttc gatactatgc tacaagaaag
    13741 ctttataaaa aaggggagtg ctcaaaagct gcacttccct tttttatgtt tctccactaa
    13801 tcgaaattta gatagacatc tagaaatcgc aattccaaaa aattctgtgt attggatacg
    13861 catcttttct tattttttct tatttcttcc atatgggtgt ttatctcaga gatgatagaa
    13921 tagtttctag gataaaaagt agcagctacg atgttatcct tcgtagagga ttcctgcttc
    13981 agctagtttt tgtttgatgt ttttcagcat atgcttttct gggtagcgga tcgtatgcag
    14041 atggatgccg cctgttaatt cggataacaa agtagcatta cttttttgat aacgtctcat
    14101 aaaggaatcg atatcttgtg gcgttttgat gtgcaaagtt cctgctaact caccgtaaag
    14161 gggatgttcc acaattacat caatgatttc accaccattt tcaacgatta gtctcagttc
    14221 ttcttctgtt tgatcttttc catgctggac agcgatttta ctgatgtgcc cagtattggt
    14281 ttcttctgtt tcgaggatat aacctcttgc tgttgccacg atacttttac ctgcagctcg
    14341 tagtaaagca atatcgccta caatgatctg acggctgact ccaaaagttt tcgcaaactt
    14401 gctagcactc actggttttt ctgtatttgc caaggtttgc atgatttgtt ttcgccgtgt
    14461 ctctccttcg atcacactta ttcctccttc attttgtttt ggtattcgcg cgagtgtttc
    14521 atcaaatcaa catacgtgtc tgttattgtt tccttatatc ccttattttt cagcagacta
    14581 acaactttat ccaatacttg ctgctctctt tttgcatcat aaactgcttg gttttcttct
    14641 tttttcactt gtcctatttt agttaccgta tccattcttt tttctaataa agcaaccaac
    14701 tctcgatcga tcatatcgat cttatgacgt aatgtttcaa gagactcttc tgttagttct
    14761 tcctctactg tcttgatgat acgagcagga tttcctgcaa tcactacatt gtcgggaaaa
    14821 gatttggtca caaccgaacc tgcgccgact actacgttgt cccctagagt gacacccggc
    14881 gtgacgataa ctcctccgcc taaccaaaca ttattaccga ttttaatggg ttttgcgtac
    14941 tccagaccgc tgttacgttt cactggatgt agtggatgcg tcgccgtgta aagctggaca
    15001 ttcggagcga acatgcagtt atcaccgatt tcaatcgtgc tgacatctaa aaatgtacaa
    15061 ttgaaatttg cataaaaatt ctccccaaca aatatattat atccgtaatc aaaattgata
    15121 actggctcca tatagatttt tttccctgta cggccaaaag tctctttcaa caattgggat
    15181 cgcagttccg ctgattctgc ttggttgatg atttggcttt gacttcttgc aaacatacgg
    15241 tcggcaacca gctcaggatc attggcaaaa taaagctcgc ctgcaatcat tttttctttt
    15301 tcggttttga attcagtcat aatctgctcc taattcttgt atttttttga aaacaaccgc
    15361 tccgtcttct tgaataaacg tataaggctc cgctaaataa acaggcgttt gattgattac
    15421 taagattttg gctgacggct ggcgaaactg taccagatca caaaacggat gaacttgaaa
    15481 actcgttcca acaatgacga tcagctctgc ttggctgacg gcataagccg cctgctccat
    15541 gactccatct tgaaaccctt caccatataa cacgatgtct gggcgtattt gtcctccgca
    15601 tgcttgatgt ttgtcgctgt gaagatattc tttccagtct accgtttgtt gacattttcg
    15661 acaatgacat tgatacagac tcccatgaaa attgacgagt tgcgggcttt tagcctttgc
    15721 gtgcaaaccg tcgatgtttt gggaaacaac ccaaacattt ttttctttcg ctagatgtgc
    15781 tatttccaaa tgaatgatat tgggttttgc ttcaggatga taaatctttt tgacaaattg
    15841 atagaattta tccggttcat tcaccattgc ttgatgactc agcaagtatt ccggctgctc
    15901 catcccgtgg tagattcctg acaaagatcg atagtctggc actccagaag gtgtggatac
    15961 ccctgcaccg gtcaaaaatg taatttgctg ataagctaat atctcttttg ctgcttcgtc
    16021 tactgttaat tgtttcatgt tttgtcacct cactttccat tatagcccat actcgaacaa
    16081 atttattgtt gaaaagtcag aaaaatggga ataaaaaagt gttatgggca tttgagcaat
    16141 ttatcacaat gttcactgac aaaagaatga aaacgtgtta caatactgct gtataaaagt
    16201 gaggtgaatc gatatgttac cattctttat ttattggggc gttattctgg cttgtatcgc
    16261 ctggttagcg ttaagcgttt atttctctgt tttttatctt gtacgcaaag aaaatggaaa
    16321 tctttgggct tttgctttat tcaacgtgat tgccgcaatt gttttagcca ttacattagc
    16381 cgtatatcga acatggggct ggggaatcac ccaatactca agtttgattt atctaatatt
    16441 agccatttat ggcgtcgttg ttcttttgca agcgatccta ggacgtgagc caaagaaagc
    16501 ggcagcttaa atgatcgaga tggaactgga cacaggaaat tttctgttct agttcttttt
    16561 ttattgtatt acatacattt ttgtgtataa ttatactatc gtttgcaatg gatagatgat
    16621 tcacattttg attgtttttt cggtaaaagt aaagatttct atatttatca gtattttttc
    16681 aaaaaccagc agttatagat tgacaaagcc tctcgagtat cgtaaacttt ttttgtataa
    16741 ataactgaat acgagatgcc tcaatcaatg aggtagaggt cgcgagaatc attaaccctg
    16801 tggagtgaag caaacatgga gaagcaggaa tagggaggat cgccgaaatg tgcacttttt
    16861 tgcttggagt gtatgttggg acgcaagtta agagcttgcg gactgtctta gcagtgatgc
    16921 taagttgcgc tatgttttgt gagaggttta tcaccttatg gaattttagc ggccttttta
    16981 tatctataaa tcggtcgctt tttatttttt cagataaagc tttaccgcat ttcatctaga
    17041 ccgctcgtgt atcatataat cagaaaggga gaaaaaaatg aaaaaaaata tggtttcagt
    17101 tgccgtacta tttgcttttg tcttctcact attcagtgtg ggatctctgg caaatgcaga
    17161 tgaaaaaaca ccgagcgatg agtttcgcgt aggtatggag gctgggtatg cacccttcaa
    17221 ctggtctcaa caaacagatg agaataatgc cttgccaatt caaggccaaa atagttacgc
    17281 cggcggttat gatgttcaaa tcgctaaaaa agtagcagat ggtttaggga aaaaattagt
    17341 catcgtccaa acgaaatggg atggtctggc tcctgccctt caatcaggca agatcgacgc
    17401 gatcatcgcc ggaatgagcc ctactgctga acgacgaaaa gaaattgatt ttaccgatcc
    17461 ttattacgaa tcacaattag tagtagtagt tcaaaaagat agcaaatatg caaaagcaaa
    17521 aagtttagca gatctttctg gagcaaagat cactgctcag ttaaatacat tccactatac
    17581 tgtgatcgat cagataccag atgtgcagaa acaacaagca atggataatt tctcagcaat
    17641 gagaacagct ttagcttctg gaatgatcga tggttatgtc agcgaacgtc cggaaggtgt
    17701 aacggcaact agtgtgaaca aagacttgga aatgcttgaa ttcagcggtg cagatggctt
    17761 ccagacaaac ccggaagatg ttcagatttc tgttggtatg cgtaaaggcg acccggatat
    17821 ccaaaaagta aaccagattc tttctggcat ctctaacgat gaacgaacca aaattatgga
    17881 ccaagcagtc aaagatcagc ctgctgcaac tgatagtgaa gaaaaacctg gcatcatttc
    17941 tgatttcact acgatttgga aacaatacgg caatatgttc ttacgaggtg ctggacttac
    18001 cttgttcatc gcattgatcg ggacagttgt cggtactaca cttggattac tgattggtgt
    18061 cttccgttcg gtacctgaat caggaaatgc actgactcgc ttcttccaaa aaatcggaaa
    18121 tgcacttctt tctatctatg tcgaagtatt ccgcggaaca ccgatgatgg tacaagcaat
    18181 ggtcatcttc tacggtctgg cactcgcttt tggcatttca ttgaaccgaa cgattgccgc
    18241 tttgtttatt gtctctctca atactggagc ttacatgaca gagatcgttc gtggggggat
    18301 ttttgcagta gatgaagggc agttcgaagc tgcgcaagcc attggtatga cccatggcca
    18361 aacgatgaga aaagttgtta ttccacaagt tttacggaat atcttgccag caacaggaaa
    18421 tgagtttgtt atcaatatca aagatacagc agttttaagt gtaatcggcg tagctgattt
    18481 gttcttccaa ggaaactctg cttccggtgc gaatttccaa ttcttccaaa catttacgat
    18541 cgtcgggatc atctacttag tcatgacctt tacgatcacc agaatcctgc gggcggtaga
    18601 aaagaaaatc gatggtcctt cagcttatac caagcttgaa gaaatcgaca attcaaattt
    18661 gcaggaataa ggaggaagaa tcatgaatga aaaaattatt gaaatcaaac atctaagaaa
    18721 aagcttcggt gaaaatgaag tattgaaaga tatcagcgta acagtcaata aaggtgaagt
    18781 tgtgacgatc atcggttctt ccggttctgg taaatctact ttcttgcgct gtatcaattt
    18841 actggaaaaa ccaacaggcg gcgagatcat ttataatgga gaaaatgtat tagctcctaa
    18901 atataattta cctaaatatc gaacgaatct aggtatggtt ttccaatcct tcaacctgtt
    18961 caacaatatg aatgtcttgg aaaactgtat gtctggtcaa acaactgtcc tgaaacgaga
    19021 taaagaaact gccaaaaaag tagcaatcga aaatctggaa aaagttggta tggatcgtta
    19081 tatcgaagcc aaaccagcac aattatctgg tggacagaaa cagcgtgtcg caattgctcg
    19141 ggcattatca atgaatccag atgtattgct attcgacgaa cctacttcgg cgttagaccc
    19201 tgaaatggtt ggcgaagtgc ttaatacgat caaagactta gcacatactg gcttgacaat
    19261 gcttatcgtg acgcatgaga tggaatttgc aaaagatgta tctgaccgtg tcatttttat
    19321 ggataaaggt gtgattgcag aagaaggtac accagaagat atctttgtcc atccgaaaga
    19381 agaacgtaca aaagaattcc tttcacgtat tttaaatgct taggatcaat agctgattgg
    19441 gacaaagagc tgcggtgttt accgcagttc ttttttatga attactcata aaaggtaaat
    19501 ttctgaaaat tttggaatct tagttgtgtt tttcagaaaa ctctcttaat atggaagtaa
    19561 ttaaactttt ttagttagga tgatttaaaa atgaatgaag agcaagaact gcagcgtgga
    19621 ctgaaaaata gacatgtcca actgatttct attggcggag cgattggaac ggggttgttt
    19681 ttaggttccg gaaagtctat ccagctagct ggcccttcga tattgctcgc ctatcttatt
    19741 actggatgca tctgtttttt cattatgcgt gcgttaggcg aacttctgtt atcaaacacc
    19801 aataaccatt cttttctgga ttttgttgca gaatatcttg gcaaaaaagc ggctttcatc
    19861 actggctgga cgtattggtt ctgctgggta tcgattgcaa tggccgattt aacagccatc
    19921 ggaatgtatg tacgctactg ggcgcctggt gttcctcagt ggcttcctga actgattgca
    19981 ttaggtcttc ttctttgctt gaatatggtg gctgtctcat tgtttggtga gttagagttt
    20041 tggtttgcat tgatcaaagt tgtagcgatc attgccttta tcctcgtagg agcttatatg
    20101 atcctcaccc actatacgac agatattggc acagccagta tcacgaatct atggtctcat
    20161 ggcggattct ttccaactgg tgcaaaagga tttatcttag ctttccaaat ggtaaccttt
    20221 gcttttgctg ggatagaatt agttggatta gtcgctggag aaacagaaaa tcctgaaaaa
    20281 gtgttgccgg aagctatcaa taatattcct atcaggatca tcttatttta cttaggatct
    20341 ctttttgtca ttatggcaat ctatccatgg aacagcttga atccagataa cagtccattt
    20401 gtagaagtat tttcggaaat tgggatcacg attgctgctt ccttgatcaa tttagtcgta
    20461 ttaagtgcag cagcttctgc ctgcaacagt gcaatatata gtacaggacg tatgcttcgt
    20521 tctttagcgc aagaaggcag tgcccctaaa aaattcaaaa agttaacaac acatcatgtg
    20581 ccagggaatg ctttgacatt ttctactatc gtcattttca tttctgttat cttgaattac
    20641 gtgatgccta gtgaagtatt cacactagta agcagtattg ccactacttg tttcttgttt
    20701 atctggagta tgcttgtcta cacgcacatg aaatatcgta aaagtatcct cggcaaaaaa
    20761 gctcattcat ttaaaatgcc gttgtaccca tttagtaatt atctggtatt tctttacatg
    20821 gcctttgtgt gtgtcgtctt gttcctagga aaagatacga gaatcgcttt attactaaca
    20881 cctgtgtggt tcttgcttct attactaatc tatcatatga aatatgaacg taagaagtaa
    20941 gaaagtagtt gtgacagaag tggtcagctt cgagaaataa gaaggaattt acgaaaattg
    21001 cttcttaaat ttttgtgaaa tttcggctta tttcttggag ataaaagctt ctgtcccagc
    21061 ctcttttcta tttccccgga aacaaccgct gataataggc atctgctttt ttataggaaa
    21121 aaatccaaat accagataca aaaaaacgtc cgaataaccc gatcaacggt acaaaaaaga
    21181 caccggcaat caagcataag ttaatcatca tggagataag acttcgacgg tcctttgaca
    21241 aaactctcac gacatgggaa tctggtttat ttgctttcat gatttgcctc atcaagatac
    21301 caaaagaaaa actccacatc gtgtatacta agacataagc catctcaggc caaaaagctt
    21361 cagggttacg cccgacccaa ctagtaacag aaggacataa agtcagccaa aagagcaaaa
    21421 agatattcga ccagaccact cggtaattaa ttcgttctgc catctgaaat atacgatgat
    21481 ggttcaccca gatcaccgca acaaatataa agctgatggt ataagctaat aatgtatttc
    21541 ggatgaccca taaagaatga aagctagatg tattagggat cttgatctct aatacaataa
    21601 ctctcaaaac aatggctacc actccatcag taaatgcttc taatctcgac tttgtcacga
    21661 tgattcctcc tcagatgatt cagcgctttt attttatcac ttacgttatt aaataaccat
    21721 cgttttatat agggaatttt ctgaaaattg ttgcatattt ttcgaaattt tgttactttt
    21781 aaaaaaaccg taaaggagtt atgtatgaca aaaaaattat catttaaaga ctatcttttt
    21841 ataggctcca tgcttttcgg tctatttttt ggtgctggaa atcttatctt tcccgttcat
    21901 ttgggtcaag aagcaggcgc tgctaccttt tgggcgaatc taggtttctt ggttaccggt
    21961 atcggtcttc ccttcttagg ggtgattgcc attggtgtat cgaaaagctc aggtgtatat
    22021 gaattagcaa aacggataaa tcaaacatat gcgatggttt ttaccatctt gctttactta
    22081 gttatcggac cgttttttgc tttacctcgc cttgcaacca catctttcga gattggttta
    22141 gcaccattta tcgatcctag cagacagacg ctatatctag caattttcag tattgtattt
    22201 tttgtgctgg cttggtggtt ttcaagaaaa ccgacaaaga tattagatta tgttggaaag
    22261 ttcctgaatc ctgcattttt ggttttatta ggtgctttgc ttctccttgc ttttttgaat
    22321 ccactaggtt ctgtaaatca agcgcctatt cagccaaatt atcaagagca tgcttttttc
    22381 acagggttta ctcaaggata taacacatta gatgcgcttg ctgctttagc atttgggatc
    22441 atcattgtca caacaatcca aaacatgggt gtaacaaaac ctgctgaaat cgctaaagac
    22501 acgatcaaat ctggtgcgat cagcattata ttgatgggaa tcatttatac tttgctcgct
    22561 tatttaggtg ctatgagctt aggtagcttt gctctaagtg aaaatggcgg gatcacgctg
    22621 gctcagattg ctgatcatta tttaggtact tatggcagta tcttattagc atttatcgtt
    22681 atattagctt gcttgaagac cggtattggt ttgattacag cttttgcaga aacattcaca
    22741 gatttgtttc cgcaaagaaa ttacgcattc tttgttgcac ttgctagtat ccttccttgt
    22801 ttagcggcaa acgtaggctt gacgaatatc attcaatttt cgttgcctgt tttgatgttc
    22861 atctatccat tagcaatgac actgatttta ctagtgttag ttggtccttt gtttaagcag
    22921 cgtacggctg tttatcgaat gactacttat tttacattga ttgcttcgat ttttgatggg
    22981 ttgaacgctt gcccagaaac tatcaaacaa acacctattg ttcaaaatct tttatatgtt
    23041 gcggaaagct acttgccgtt tttcaaattg gggatggggt ggatcgtacc agcagttatc
    23101 ggttttgtta tcggactgat ttggagtttc gctaagaaag aagaagtagc agattgataa
    23161 aagaggttgt gaaagagacg ttcagccttg agcaataaaa agtaattttg aaaaatggct
    23221 tctcacattt ttgcataaat ttgacttaat accgagaaac tgacttttga acaccgttta
    23281 ttgagaggtc gtgaaaaagc cgcttagttt caagtattaa gaaatatttt gtgaaaatgg
    23341 cttctcacat ttttgcataa atttgactta ataccgagaa actggctttt gaacaccgtt
    23401 tattgagcgt ctataaactg acctgagtat tagagaaaca aaacggcaaa gtagctccat
    23461 atactttgcc gttttgtttt gaactaatac cgaagagaag ctgatcaaac aacatttctt
    23521 ttataatata gattttagac atatatatga tataaaaata gttttcgcaa aaaaa
//
LOCUS       DAXQKX010000041        23432 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.041, whole genome shotgun sequence.
ACCESSION   DAXQKX010000041 DAXQKX010000000
VERSION     DAXQKX010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23432
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.041"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(10..2154)
                     /locus_tag="ACF3MF_001799"
     CDS             complement(10..2154)
                     /locus_tag="ACF3MF_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFE3927785.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQTADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFEPVPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(2511..3884)
                     /locus_tag="ACF3MF_001800"
     CDS             complement(2511..3884)
                     /locus_tag="ACF3MF_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFE3927786.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPIMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(3884..4279)
                     /gene="rbsD"
                     /locus_tag="ACF3MF_001801"
     CDS             complement(3884..4279)
                     /gene="rbsD"
                     /locus_tag="ACF3MF_001801"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016872 - intramolecular lyase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HFE3927787.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGSEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(4307..5224)
                     /gene="rbsK"
                     /locus_tag="ACF3MF_001802"
     CDS             complement(4307..5224)
                     /gene="rbsK"
                     /locus_tag="ACF3MF_001802"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006014 - D-ribose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HFE3927788.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(5333..6346)
                     /locus_tag="ACF3MF_001803"
     CDS             complement(5333..6346)
                     /locus_tag="ACF3MF_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HFE3927789.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQISHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEESGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(6427..7029)
                     /locus_tag="ACF3MF_001804"
     CDS             complement(6427..7029)
                     /locus_tag="ACF3MF_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HFE3927790.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKGIVNNGTLSPHTAQSILTNN
                     DLLAKTLKRTAALKVLVNVDITTFSYLSHQTDAGGISALSAPAEFTDLLLKDSLKDTN
                     NMLTITKYNPSAFFGTSLDLQLRRRGIETIVLSGVATTNGVYATALDAFQHGYHVVLA
                     EDACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            7214..7915
                     /locus_tag="ACF3MF_001805"
     CDS             7214..7915
                     /locus_tag="ACF3MF_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3927791.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            7925..10636
                     /locus_tag="ACF3MF_001806"
     CDS             7925..10636
                     /locus_tag="ACF3MF_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFE3927792.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEHNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKITEGKAQIAQGRTQ
                     LEDAKKQLAQQSAAIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKAAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWSYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            11033..12661
                     /gene="treC"
                     /locus_tag="ACF3MF_001807"
     CDS             11033..12661
                     /gene="treC"
                     /locus_tag="ACF3MF_001807"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HFE3927793.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRITIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(12721..13902)
                     /locus_tag="ACF3MF_001808"
     CDS             complement(12721..13902)
                     /locus_tag="ACF3MF_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFE3927794.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSVW
                     LVPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            14154..15680
                     /locus_tag="ACF3MF_001809"
     CDS             14154..15680
                     /locus_tag="ACF3MF_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZinT/AdcA family metal-binding protein"
                     /protein_id="HFE3927795.1"
                     /translation="MKRLIGILAMLVLAGMLTACGGASGKAEDSKEKLSVMTTFYPMY
                     DFTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQK
                     TLQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVAN
                     IRDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLAL
                     EYGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGV
                     SLEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNG
                     YFEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGY
                     QTDIASIKISEKEMAFTFKDGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGA
                     FRYIQFRDHTIAPADSEHFHLYAGNESQEALLKEMENWPTFYPDTMDGREIAQEMLLH
                     "
     gene            complement(15749..16477)
                     /locus_tag="ACF3MF_001810"
     CDS             complement(15749..16477)
                     /locus_tag="ACF3MF_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFE3927796.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(16490..17770)
                     /locus_tag="ACF3MF_001811"
     CDS             complement(16490..17770)
                     /locus_tag="ACF3MF_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFE3927797.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIALSAFLSALLAFCFKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYAQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLVVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(17911..18513)
                     /locus_tag="ACF3MF_001812"
     CDS             complement(17911..18513)
                     /locus_tag="ACF3MF_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HFE3927798.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFALEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            18759..18965
                     /locus_tag="ACF3MF_001813"
     CDS             18759..18965
                     /locus_tag="ACF3MF_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927799.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            19278..19997
                     /locus_tag="ACF3MF_001814"
     CDS             19278..19997
                     /locus_tag="ACF3MF_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFE3927800.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(20078..20761)
                     /locus_tag="ACF3MF_001815"
     CDS             complement(20078..20761)
                     /locus_tag="ACF3MF_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HFE3927801.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            20993..23179
                     /locus_tag="ACF3MF_001816"
     CDS             20993..23179
                     /locus_tag="ACF3MF_001816"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HFE3927802.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
BASE COUNT         7812 a         4209 c         4584 g         6827 t
ORIGIN      
        1 taatttattc tatttcttta aaggcagatc aagccagaat gatttgtcta aacttaacaa
       61 ggttagtaca ggaacagttg cagctttaac tgtacgagta gttgtttctg gtatctgtct
      121 tgccgtaaaa ttgttccaca aatcccagat tgaagcgaca cggaagatgg aagaagcgtt
      181 gttgacgcgt tttatcgttg aaaattctaa tcctgtgatt ggcacgccat ctgttgtcca
      241 tttgattggc acatcgaatc gcttagacat attgaggatt tcagcgtttg cttcttcagt
      301 tgttgctgct tcttttttcg gttcatcata ttttgtcagg tcgtacgctt cgatgatcgc
      361 gttcaatttt tgtgaatatt ggcgatctgt agcataacgt ccttccaaat atttggttgc
      421 ttctttgtag tcttttgttt ccgacttcca agttggtttg tagaaatcag gattgccagt
      481 cagtccattt ttgatcaagt cggcatagtc ttccaaactt tccttgtaag aaggatattt
      541 acggaattgt gcgcggattt ggtagctttg tccggaacta tcttgttcaa gtgtattgaa
      601 ggtcacgctg cttcctttat atgatccttt gataccaaaa aggttatgat ttggttcgct
      661 tgataataag ctgtttccag atccactttc aaggatagct tgagccatca tgactgatgc
      721 gtagattcct tctttttgcc cgatttcctg tgcatcatct gcaatctttt tcaagaactg
      781 atcagttgtt tggttttgac tgaaatggaa cgagccatct aatccatcta aaatagatga
      841 gccgcctgtc agcgaacctg aagcagcagg taaacctgct aagtttactc ggacagcaaa
      901 atcaggcgtg aaatctgaaa tagaagttac tcgaacttta tctcctggtt gaggcgcatg
      961 gataaattgt ccgttcccaa tatagatacc tacgtggtgg gtaacaccag aagaaggtcc
     1021 ccagaagacg agatcaccag gttgggcctg acttactgga atctgtgtac ctgcatattg
     1081 ctgttcgcct gtccagccac cgatataatg accggttgct ttcatatata cgtaataagt
     1141 caaaccagaa cagtcaaaag tatttggacc ttttgctccc catacatatg gttttccaag
     1201 atgcttgaat gcttctcgaa cgattgcttg ttggacattc gttgtatttg taggcaatac
     1261 agcatcaatt ggtgatttta caacaaaatc agaagaagca gaagatggat tctctatacc
     1321 gctttgattt gctgtatttg gacgagatga agcattgttc gttccgccat ttgatgaacc
     1381 attgtttgga tggtttggtt ctctctgagt atttccattg ttattcgatc cagatgggtt
     1441 tgtttgattc gaagaattcc cgctgttcga attattgtta ttattgtttg aattatttga
     1501 accattatta ttgttgttat tacccacatc tggtttgttt ggcgtttccg gatctggtgt
     1561 actagggact tcttcactag gatcagttgg tttctctgtt gaagtatccg gtacaggttc
     1621 aaattctgca gtaatagata aattgttcgt acctactgta aaggtctttg catcataatt
     1681 tacttctttg gcaccattaa cagcgactga agcaatttgt tcaccttcag ctggcgtaat
     1741 agtgtaagtt accttcgttt ccgctaataa accttctacc gttccacttt ccgtaatatc
     1801 caaaggttgc tgttcagggg aatccgctgt cgaagcagtc agttggatct taccaatcaa
     1861 agaaggagca attgtaaggg aatatgtctc ggctggcttt tcattttctg atggatcagc
     1921 cggatcaatt tcagttggct cggtcgatcc tgttgttgag ttagttgttc cagttgggtc
     1981 ttctgtaaaa gaatccgttg tttcactagt agctgagctg gatgtagtcg tatctgttgt
     2041 gactgtttga tcagctgttt gattatctac ggcaaatacg gtattggtcg acaaaacaga
     2101 cggagcaatc agccaagtag cagctagcaa acgtatcgtt tttttatttt tcataataaa
     2161 ctagtccttt tcctttcatt gattttctgt cttattcagc attcattaga cattttttgg
     2221 aacagataat cgtgtcgaaa agctttttct tttcataaat ctgtctgtgt attctaaata
     2281 aaacaatttg taaataagca acgagcattc attcgttttt cattgacgtt cattttattg
     2341 catagaccac ctttgtttgg ggataaacaa gtggggataa aaatggttat gcatatgtaa
     2401 attataccaa agtttggaaa gtatcacaaa aatttataaa aataatgatc ctaaaaagaa
     2461 aaagactgaa atatgtgata aacatctcat acttcagtct ttttcattaa ctattcataa
     2521 gacattaggt cttcatcaaa cccgctaacg agagtagtaa tcattgctac gactagacta
     2581 acagccagtc ctgctaagta ccagaaaaaa gtaccggaaa tgaatgcagg caatgtggtc
     2641 agactaccaa atacaaaagc gatcgctttc acttgggcaa atcccattac agctccacca
     2701 gcagctgcac caatgcaagc agcaacaaat ggttttttca atgggatcgc aattccgtaa
     2761 acagttggtt cggtcactcc cgcaagtaaa atcgaagcaa aagcagaacc ggagatcgaa
     2821 cgagtttttg aacgtttact tcgtagaaat acacctaaag ctgcaccagc cattccaaaa
     2881 ttggctgctc ctgtcaacgg aacgattcgg tcgaacccat aagcagagat attactgatc
     2941 atgatagggt ttacagccca ttggatacca aatattacca aaatattcca accaccagcg
     3001 atgattgcgc cgctgatcgg tccgttaata tccatcatcc aagtaattgc ggcagctaaa
     3061 ccttcgccaa ggtaaacacc cgcaggcccg aataccatta acgtcaaagg aaccgtgata
     3121 actaatgaaa gtaaaggtac aaatactaat tgcatatttt cgcgaatata ttttttgagg
     3181 aatttttcaa caaaagaata aaagaaaata cctaaaatcg ccggcatgac agtagacgta
     3241 tactgcatca gtactacagg aatccccaga aaatcagtag ctgctttgcc actgtctgaa
     3301 agtaaagagg tcagattcgg ttcaatcagt gctgcagcaa tgacagccgc aatatatcca
     3361 ttcactttaa acgttttggc ggcagaaaaa gcaagaaaga ttggcagaaa ataaaagacg
     3421 gcattcgacg cagcagacaa aatatgataa gttccgcttg tttcactaag ccagccaatc
     3481 gtagtcgcta aaacaaccag accttttaat ataccagaac cggcaaacag cggaatgatc
     3541 ggcgtaaaga tttccgatat caaaccaaat agtttttcga tcggatttag cttttcttta
     3601 ggagctgaat gatcgatttg acgcgttaat tccttgtaag caggagccaa tccctgatcc
     3661 atgattattt ctgcatatct atcgagtaaa atgaaatact taatggaagg gatttgctgt
     3721 tttaattttt ctgcattggc tactggctgt tttttcaatt tgatacgaag ccgagtcgca
     3781 catggaagga cagaatcaat attgtctttt cctcccaact gttcaatcag catatgaatc
     3841 tgctcggaca gtaccatctg ttcaggattc attgtcgttt ccattagaag accactccac
     3901 tcactaatat aatattggcg taaggtgtca tttcgcctgt acgaataaat gcatgacagt
     3961 tattcaactc ttttttcatt tcttcatgtg ggataaagct aatcggtgta tctggtaaca
     4021 ataatttgat tttttccaat atttccgggt tcattgtctt tatttcttcc gccaattcaa
     4081 tcgattgtac ctcaagttct tctaaaacgt tttctaaaac agataaaaag cttggaagac
     4141 cgtttgagac agccaaatct attttttcac taccaaaggg gacaggcatg cctgcatccc
     4201 cgatacttaa tttatcaaag tgccccattt gtgcgattac tcgtgaaata tctgaattga
     4261 ttacttttcc ttttttcatg tttgtttctt cctctcattg ttaattttag actgctgatt
     4321 gttctaaagc ttcgcggtaa gggatagaag gttgcgcacc ataagactgc acagcaacag
     4381 aagaggctag atttccataa aggatcgctt ctttcaagtt actaaggtct ggctgaagtg
     4441 tgctgcttaa tgcgccaata aatgtatcac ctgcggctgt tgtgtcaacg gcatccactt
     4501 taaaagcagg gacgataccg tgttcttttt ctgtatgata gaaagcgccg gcactgccta
     4561 gtgtaatgat tactgttcca atacctaatt catggagttt ttcggctgct gcgaccaaac
     4621 tgttatgatc tgtcactctg attcctgtaa tgatttctgt ttctgtttca tttggtataa
     4681 tgatatctgt tttttcaagt agttcagtag ggatcgtttc acgagctggt gcaggattca
     4741 ggatcgttgt ttttcctgcg tcttttgcaa tagaaaaagc taggatcgtc gcatctaagc
     4801 tactttcaaa ctgagcaata ataaagtcac tgtttgtaat cagttgcttg ttttttagga
     4861 cttcttgttc atggaaagca ttatttgcac ctgcatggat caagatacta ttttctcctg
     4921 ctgcgtctac cataatcatt gcttgtccgg ttgtggcgcc ttggatttca gctatcccag
     4981 atgtatcgat gttttctttt gtcagtagat ctaataactg ttgtccttcg ctgtcagccc
     5041 caacgcctcc aataaaagat gtccgtgcgc ctgaacgttt ggctgccact gcttgattgg
     5101 cacctttacc tccgccagcg tgaaaaatct catgcgcatg cattgtttcg cctggcttgg
     5161 gcatgttggt taaacgaagg gtagtgtcca tattaatact tccaattact gtaaccgtgt
     5221 tcattttaca aacctccaac tatctcattt attttgatgg gaaaaattat tttttaaaac
     5281 gttttagtaa aacgttttaa tagttcgata aaaatatagc acaccttgaa agctatttca
     5341 agggtgcagt tgaaaatctt ttttctaatc gtacaggtaa tcttttttct tcccattctt
     5401 tttctgggaa ttggatccga tctaacaata atttggcaga tgtttgtccc aattcgaaga
     5461 tcggttgtgc gatcgttgtc agtttcggct tgatatactc gcacatatct atattatcat
     5521 agccaataat gctgtagtct tcaggaatgc tttttccaga ttcctctaat ccgcgatata
     5581 atccaaaagc taattcatca tttaaagcaa acacaccagt tgcagcagaa tcaagaagtt
     5641 ctgctgtgat ttggtagcca ccttgttttg agaactgtgt aggtaagagg atcagttggt
     5701 cgtgagagat ttggtaaaca tcaagagcag atttaaaccc ctcaatccga gcgtggacat
     5761 tttccggcgg attttcagga tagacaaggg cgatcgtttg atgacctaga ctaagcaagt
     5821 gcatgcccgc taggtaacca ccgcgaaaat cgtctgttcg tacggcatca ctaaatcctt
     5881 cagatttttt ctgatccaaa acaatgaagg gccggccttg ttttttcaaa ttttcgttga
     5941 ttgcatctgt agagacagca gaagtcgcga taatgaatcc atccacacct cgacgtgtga
     6001 gctcggctag atattcgatt tctttttgat gatcagaatc agcattacat aatatcgtga
     6061 cgaaattctg cttatacaag atatcctcaa ttcctcgcat cagtgtactg aagaatggat
     6121 tcgtgatatc aggaacgagt acaccaattg ttttcgtttc cttggtaatc atttgtctag
     6181 caaaatagtc aggctgatag cctaattctt ctttggcagc taaaactttc tgaacagttt
     6241 tcggactgaa tttctccgta tttccattta atatcaagga gacagttgtg attgaaacgc
     6301 cggaaagttt agcgacttct ttgattgtga tctttttttt caccatgttc atactcctat
     6361 ctaaatcctg tggttatttt cccatgaaat caaaaagaag taaatgaaaa tcacgtgtgc
     6421 cagtacttat ttgctttgtt ggatagcttc gattatttgt ttcgttgagc gtactcgtgc
     6481 agttttcgga aatatctttt ttatgaacaa ttgatgggat tctttgtcac gatcactgca
     6541 agcatcttca gcaagtacaa catgataccc atgttggaag gcatctaatg cagtagcata
     6601 tacaccgttt gttgtcgcta caccgcttaa aacgatagtt tcgattccac gccggcgaag
     6661 ttgaagatca agagaagtac caaaaaaggc acttggattg tattttgtga tagtcaacat
     6721 attgtttgta tctttcaagg aatccttcaa caacaagtca gtgaattctg ccggagcaga
     6781 caaagcagat attcctccag catctgtctg atgacttaga taagagaaag tagtgatgtc
     6841 tacattcact aaaactttca aggcagcggt acgtttcaat gtttttgcta acaaatcatt
     6901 gtttgtcaga atagattgtg cagtgtgtgg agagagtgta ccgttattta cgatcccttt
     6961 ttgcatgtcg atcgcgacaa aagcagtttt tgataaatca aaaatcatat tttcctttaa
     7021 atcattcatg atgttccttc tttcaaataa caatgttttt tatgtaagta aatcataaat
     7081 cgtttatttg tcaactaaat aaaggattcc tttctttagt ctagagaaat tcagtggtaa
     7141 aataaataag tatgagaaaa cgcattcgat gcatagatat agcgagaaat atcgtgaaaa
     7201 tggaggaatc agagtgaagt atgtcgaagt aaaaaatgaa tacaaacgat acaaaatggg
     7261 agaaacgacc attacagcaa atgacgatat ttctttttca attgaaaaag gcgaattagt
     7321 gattatactt ggtccaagtg gagcaggaaa gtcaacgatt cttaatattt taggtgggat
     7381 ggatacacct gatgaaggtc agatcattat tgatgacaca gatattgcgc aattttcaga
     7441 taaacagctt actgcttacc gacgaacaga tgtagggttc gttttccaat tctacaatct
     7501 cgttcctaat ctaacagcaa aagaaaatgt ggaattggca acggaagttt ctcctgatgc
     7561 gcttgatcct gtagaggtat tgaggcaagt gggcctagct catcgattga ataactttcc
     7621 gtcccaatta tcaggaggcg aacagcagag ggtttcaatt gctcgtgcac tagctaaaaa
     7681 tcccaaactt cttttatgtg atgaaccgac aggcgcgctg gattttgaaa cgggcaagca
     7741 agtattgaaa ttattgcaaa acgctagcag acaacacggc aataccgttt tgatcattac
     7801 acataattct gctttagcgc ccatcgctga tagagtcatt cacattaatg atgctaaagt
     7861 aaggtctgtt gaattaaatg atcatccttc atccattgat gagattgtat ggtaggggga
     7921 ttttatgaaa acaagaacat atcttaaagc aggttttcgc gaaattcggc aatctaaagg
     7981 acgattcatt gcaatcatcc ttattgtcat gctaggaaca cttttatttg taggtgtcaa
     8041 aactgctgga cctgtcatgc aaaaaacgat ggaccactat gttggtacag caggactttc
     8101 tgatttgcaa atcgtttcta ctggtggctt gacacaaaaa gatattgctc aagcagaaaa
     8161 gatcccagat gcaaaagtag aaacaggaaa acagatctat tattccaata ctggtaaaaa
     8221 cgaagtgatt caaatatttt cttataacaa aaataacaag cagaacaagc tacaattaac
     8281 tgatggaaaa ctcccggaaa aaccaaacca gcttgtattg gatgaaaaag cggaagatga
     8341 agggtataaa atcggtgata tttatcagat tgattcagat gaattgaaag aaaaagagta
     8401 taccatcacg ggctttgtcc gttctccatt gttcatcaac aatttggaga gaggatacgc
     8461 gaacgtcgga aatggtagcg tcgattattt tgtctattta cctgaatccg tttttaaaac
     8521 agatatttat tctgtcttat atcttgattt tacaaacgta aagaatttga atacgtacag
     8581 caaagcttac aaagataaaa tggaacacaa tcaagagaag gcagaaaagt atttacaaga
     8641 tcgccctgaa gaacgcttag aagagctgaa aaaatcggca aacgaagaat tagaaccagc
     8701 acagcaaaaa ataacagaag gcaaagcaca aatagcacag ggaagaacac agttagaaga
     8761 tgctaaaaaa caattagcgc aacagtcagc agctatccag cagcttcctg aagcgcaacg
     8821 aacaatcgct gttcaaacat tatctcaaca agaagctcaa cttgctgaac aagaaaggca
     8881 attagttgag aaagaacgtg aactggcctc tgcagaggaa gaattgaatc gaaatgcaga
     8941 aaaaattgaa aatttaacta aaccatcata cctatacaat gaacgttcag aaaatgtcgg
     9001 ttttcaagaa tttggtgatc tgtctgatcg tatcgctgcg attgccaatg tttttcctgt
     9061 tttctttttc tttattgccg cattgatcac ctttacgaca atgacacgta tggtagaaga
     9121 aaaccgcagg gaaatcggga cattaaaggc gttaggttat acgaaagttg aaatcgcaaa
     9181 aaaatatgca atctatgcaa gtctagcctc agggataggc attgttttag gaacgatatt
     9241 aggaacgaat cttttgccaa ggatcatttt tgagctgtct aacgagcggt atgatattgg
     9301 gagtgcgctt attttttatg actggccgcc gattttacaa gcagctgccg cattcttcat
     9361 tgccgcattt ggcgctgcaa tgatcgtttt attcaaagat ttaagagaac ggcctgctgc
     9421 attgcttcaa ccgaaagcac cgaagccagg gaaacgcatt tttcttgaat acatcactcc
     9481 gctgtggtca cgccttagct ttaatcaaaa aatcagttac cgaaatctct tccgatataa
     9541 gtcaagaatg cttatggcga ttatcggaat tgctggatgt gccgggctga tggttgcagg
     9601 cgtgggattg aaagattctc taagttctgt ctcagctaaa caatttggac cgatcattga
     9661 ctatcaagca atcgttacat tggattcatc cacggaagat agtcgtcaaa aagcagcgga
     9721 tatgctgcag aagcaagaaa aagtaaatga gatcctagct attcatactc aaaccgtaga
     9781 attgagaaaa aaaggacatg cttcgcaaag tctgacagtg atcgtaccaa gtaaaacagc
     9841 tgatttggat cgttttatcc atttaactga tcttgaagag aacccacgct ccttgcctaa
     9901 aacaggaatc gctattacgc aaaaagcagc agaactattt gacttatcta caggagatca
     9961 tatttcgctt tatgatgaag atcaaaaaga atggaaagtc gaagtaaaag aaatcgtgaa
    10021 aaactatcta ggtagcttta tttatatgtc ccctgaatat tatgcttcag ttactgatca
    10081 atcgatgatg gataatgcat ttttgctgcg tacagataag atgacaacaa aagaagaaga
    10141 aatgctttcc gagaaactgc ttgccacaga cgctgtgaca aatacgtctt tcatgtccaa
    10201 acaaatcgaa acgcaagaag aatcaatggc gaacttagac tcggttgtct taatctttgt
    10261 cgtattatca ggactgctgg cttttatcgt cttgtataat ctaactaata tcaatatttc
    10321 cgagcgtgta cgcgaattat ctacaataaa agtccttgga ttttttgata aagaagtcac
    10381 gatgtacatt gttcgagaaa atatcatctt tactctttta ggaatcatcg gaggatttgg
    10441 tgtaggatat atattgactg acttcatctt gcaacaagcg tctatggaga atgtcatctt
    10501 tccattagtg atcacatggt ggtcttatgt cttatcagca ggattaacta tcgtatttac
    10561 ggttattgtg atgattgtta cccatttcaa attaaagcat atcgatatga ttgatgcgtt
    10621 gaaatcgaat gaataaaaac agaggttgtg aaatcagcgt tttgagctaa taacgagggt
    10681 cagctgctaa ttgaacaccg tgaatcagag gttgtgaaaa agctgtcctg catcgagcaa
    10741 aaggaatact caaataaaat tagctcctca tgttttacat ttgagaagac tgattgccgt
    10801 agataaaagc ttttgagcac catttataga agaaacaaga atattttgct attttaaaca
    10861 agaggataga caaatacatg tctgatctct tgttttttat tgggcaacag acctcttaga
    10921 atgtataaag ataagtttta caaacgcttt ctgttcagtt ataataataa atgataactt
    10981 gtatatataa gttgcggtag gtaataaatc agttgaatgg aggtaaatat ccatgacatt
    11041 taaagacaaa gtcatttacc aaatctatcc caaatcttac aaagacagta atggtgatgg
    11101 aattggagat ttaaaaggaa tcaaagaaaa actcccgtat ctgaatgatc taggcatcga
    11161 catgatttgg ctaaacccta tttatccaag ccctcaaaaa gacaacggtt atgatatctc
    11221 tgattacaca gccatcgatc ctatctttgg tacgatggag gaattcgaac agctaatagc
    11281 cgaagcaaag aaataccgga tagaaatcat gctcgatatg gtgctgaatc acgtttcgac
    11341 agaacatgaa tggttcaaaa aagcactagc aggggaccag cattatcagg acttcttcat
    11401 tttaagagaa gagccaacgg attgggtatc aaaatttggt ggaagtgctt ggtcgccatt
    11461 tggagatacg gggaaatatt atttgcactt atatgatcgg acacaagctg acttgaactg
    11521 gcggaaccaa gcagtaagag aggaactatt caaagttgtt cgtttttgga tggaaaaagg
    11581 ggtaaaagga ttccgtttcg atgttatcaa tgttatcggt aaagacgaac aattgaaaaa
    11641 taacaaagaa aatgatggca aacctgaata tacggacaaa ccaatcaccc atacgtatct
    11701 aaaagaattg aaccaagcaa cgtttgggac ggattccact atcatcacag tcggtgaaat
    11761 gagctctacg acgatcgaaa attgtatctt gtatacagaa cctagtagag aagaattatc
    11821 aatggtcttt aatttccatc atttgaaagt cgattatgaa aatgggaata aatggtctac
    11881 tcctccattt gattttgcag aattaaagcg actatttcat acatggggag aaaagatgag
    11941 tgagggtaac ggctggaatg ctctattttt taataatcat gatcagccac gtgcgctcaa
    12001 tcgatttgta gctatcgatc agtatcgaaa acaaggagca gagatgctag caaccatgat
    12061 ccatttgaac cgtgggacgc cctatattta tatgggagaa gaaatcggca tgatcgaccc
    12121 agactattca tcgatttccg actatattga cgtagaaagt ttgaatgctt ataagttact
    12181 ccttgaacaa ggattcacag aaaaagaagc gtttcgtcgg atcaaagcaa aatctcgcga
    12241 taactctcga acacccatgc aatggtcaga cacagaacaa gcaggattta ctacagggaa
    12301 accttggtta aaagttggag gcaagctaga agagattaat gtagaaaaag aactatcttc
    12361 tgaagattct attttgtcct attacaagaa attgattcgg ctgagaaaaa catatccaat
    12421 cgttgcacaa ggagattatc atgcttatga agcaaatcat ccggaagttt atggctttct
    12481 tcgccaattt gaaggacagc agctgcttgt attaacaaat ttctatgata aagatacaag
    12541 gatcaccatc ccagaaggat tcacagaagc caatattctt atcgataatt attccgatac
    12601 tgttcttcat caaagtctgg agctaaaacc ataccaggca attgctttgc tgaaaaatta
    12661 aaacaaaaac acaaaacgtc gttcctacga gctattctcg taagatcgac gttttgtgtt
    12721 ttatttaaaa taatcttctt cagaaaatga agagttttca tactctcctt tatcgccata
    12781 aaatttattg tagcgttgtt tgaatttacg gaaaataaaa gtaacgagta atttgactaa
    12841 cgtatagata ggaataccaa aaataacgcc cacaattccc attagatcac ccatgacaag
    12901 taaaacgatt aagatcgtaa tcggatggat ctgtaaacga tcacccatta ctcgaggaat
    12961 caccaagtca ccgtggagaa gttgtacggc aaaccagaca atgacaaatt tgacagccat
    13021 aaaagtagag tcttggaatg caatgatcaa acctggaaag aaggcgataa acggcccaat
    13081 atatggaatg atacataaca acccagcaga aatagctaaa acactagcaa attctaatcc
    13141 gatcagtaag aaacaaaccc agtagactgc tccaaggata aatgaagcaa tgatttgccc
    13201 ctttagaaat gaacccaatt gttgattagc aatctttgtc aaatttttaa aatctgtacg
    13261 aaatgctggt gggacaatcg ctaaaactga ctgataaaat ttttgaggat ctctcaaaag
    13321 aaaaaaagcg acaattggac cagtaaataa agtaataaaa atagctgtaa cagttgaaaa
    13381 aatgttgctg atccgttgtg cgccactttc ccaataattt ccaataaatc cagctatatc
    13441 agacgtcacg tcgtcaatag aagcgaaaaa ttgattaaat gaatcggcaa aaggtgtttt
    13501 ctctaaaaat tgtcggagac tctcttgaaa atcttgaaac aaatctggca aactactgat
    13561 caatgtcttt gcctgttctt caagaaaagg aacaagccat acgcttccaa gccccaataa
    13621 aaataaaata atcacataaa cgataatgac tgacaagttc ctcgaaaggt gcttgctcaa
    13681 acgtttgatg actggttcca aaagataata caagatcagt gcaaacaata atgggggcaa
    13741 gatagtagcg ataatgattc cgacaggctt gaatataaac gagatctgat ggaaaaaata
    13801 aatgatcagc gcaagtaaga taactattcc taaaacatag taagaggttt ttcctcctaa
    13861 aaagcggatc aaacgattcg ttgtatctgt ttcttttttc actctttttc ctcctttatc
    13921 tataacttca ttatagacaa aagcgggtat aaaaggaaaa tgatagaggt tgattgcaaa
    13981 aatatcgtca atcattcata taaactttct catcaattaa aataagaaaa cgcttgacag
    14041 ttcttttaac catatgataa attaaatcct gttgctaaaa cgtaactatt acgttttgta
    14101 aaaggcgaat cggaacattc aaatgaaaga agatgagaag aggagtgtca taaatgaaac
    14161 gattgatagg tatattggcc atgctggttt tagcaggtat gttaactgct tgcggcgggg
    14221 caagtgggaa agccgaggac agtaaagaaa aattgagcgt gatgacgacc ttttatccta
    14281 tgtatgattt tacaaaagca atcgtcgggg atgaaggaga agtagagtta ttgattccag
    14341 cagggactga ttcccacgat tatgaacctt ctgctaaaga catggcaaag atccaagata
    14401 cagatatctt tgtttataat gatgaaaaca tggaaacatg ggtccccgca atccaaaaaa
    14461 cattacaaga aggcaatgtc catacgataa aagcgacaga aggtatgctt ttacttccgg
    14521 gaagtgaaga aggacatgat catgaccatg aacacgggga agaaggccat acacatgagc
    14581 tagacccaca tgtatggcta gctccaagtt tagcaatcaa gcaggtagca aacatacgtg
    14641 atcagctgat tgaagcttac ccagaaaaac aggaagtatg gacaaaaaat gcagcagcct
    14701 ataccgagaa acttcaagca ctccatcagc tttatcaaga aacctttaag caagcaaaac
    14761 aaagatcttt tgtcacgcaa catgctgcat tcaactatct ggcattagaa tatggattga
    14821 atcaagtatc gattgctggt ctttcttcta gtgaagaacc gtctgcggcg agaattgctg
    14881 aactgaaaca ctttgttaaa gaacatggaa tcaactatat ttattttgaa gaaaacgcca
    14941 aagatagtat tgccagaacg ttagcaaacg aagcaggtgt atctttagaa gtattgaatc
    15001 ctttggaagg attgacgaat gaacaaatag aaaatggaga aaactatctt tctatcatgg
    15061 aagcaaacct cgaagcgttg aaaaaaacga cagagacaga aaacccgcta gaagatactt
    15121 tgacccccaa aaaagaaaag agcgtctaca acggttattt tgaagacgag gatgtacaag
    15181 atcgctctct ttcagattgg gcaggaactt ggcaaacagt agatacgtat gtagaagatg
    15241 ggacttttga tcctgttttt gaatataaag aaaaattgaa tcaggataag acagcacaag
    15301 aatataaaga atattatacg aagggctatc aaacagatat tgcttcaatc aagatcagtg
    15361 agaaagagat ggcatttacg tttaaggatg gaacaacgaa acgttcaaat tatcgttatg
    15421 tagggaaaga aatcttgacc tacgaggcag gaaaccgtgg cgtaaggtat ctattcgaag
    15481 cagaagataa ggaaagtggc gcttttagat atattcaatt ccgtgatcac acgattgcac
    15541 cggctgactc cgaacatttt catttatatg caggaaatga aagtcaagaa gcattgctga
    15601 aagaaatgga gaattggcca acattttatc cagatacaat ggatggacgt gaaattgcac
    15661 aggaaatgct tttgcactga taggcaaaaa agaaccgaag ggtttggatc ggctagtcat
    15721 ttagtcggtc caaactattc ggttcttttt atgaaatcaa tttctttaat ccacggatag
    15781 aggctgggat ggtctcgccg tttgccaacg tgacttctct ggttttttta ttaatcgacc
    15841 gcacattttg tgtattgata acataggatt tatgacaacg gataaaattc cgatgcattt
    15901 tctcgatttc tttgatcttc tcatagaatt gtaattgggc atgagtcaaa tggacttcca
    15961 gtttatgtgg tgctcctagc gaagtagaaa aatattggat gtctttgatc ggtaaaaatt
    16021 tgatctcatc attaaactct attttgaaga tatctttttg gatctgggac atttgaaaat
    16081 cttcgaaaat tttgctcagg atatgctcga cattttcttt taaatcataa agatcttctt
    16141 tgacgatata atcagtcggt tcgatgttgc tttttaagat tttcatcgac atttccgtat
    16201 gggaagtcac atagattatt tttcctaagg gatctaattc acggatcaat ttaccgatcg
    16261 ctacaccatc catttcactg tcttctagtt cgatatctaa aaagtaaata ccaaaagaag
    16321 aagttctgat cttggctgca ttgagaagtt cttccggatc agaggtagaa atatggacat
    16381 aactgtctaa gttttcaatc atgattctat ttttgatcac cgttgataaa acttctaatt
    16441 gttttggatc gtcttcacaa atataaatgg gaatcatatc attactcctt tattttattt
    16501 gtatataaat cgtttgagaa aaacgctggt tttcaattga tgtttcaagg aaaagataag
    16561 gattggtctt tgtcaattca tccaagataa acaagccaag gccttcgttt tttggatttg
    16621 tttttgttga gaaccctttt tgtttcaact ggtttaacgg caatgtattt gttgttgtat
    16681 tgatcacacg aatcatcacg gaatgattct tcttgagtat ggtcaattcg atttttttct
    16741 tctttgcagc actagctcct tcaatcgcat tgtccaagat aataccaagc atacgtacaa
    16801 ggtttaccgt atgtttcgta tccagttcga ttggctcagg aaaatgaagc tggacgacca
    16861 accctttttc ctgtgccatc atgagtttta atgacagtaa actacggatc tcaggaactt
    16921 tcatattatc caacatactt agattggccg gaaaaaggtt catcatctgg cgtgtaggta
    16981 atatcgtttg agcataataa gaccgtaatc cttctaagtc gccttctgaa atatagctgt
    17041 gaagagaaaa aagcagattt tggtaatcat gtttgaattc tctcaagtct tgatagtttt
    17101 tttctagatc tttgatataa tcctgttgca tcctgacttg ttgctctaat aactgatcag
    17161 ctaatttctt attagagatt ttccaataat aaaccaagat gatcaggcca acacacagat
    17221 atagaatgaa aaaactcgta ttcaaagcta agacatcagg tgtttcacca gaaaaacggg
    17281 tataaaaaat aatgatatag tatgtaaata atatcaatgt cccgatcgta ccgatcatac
    17341 ggcggtccac agtgtgaaac caagtctcta acgatttttt aaaacaaaaa gctaataaag
    17401 cagataaaaa agcggataag gcaatgtgaa aatactgcaa tgaatctcct ggttcaataa
    17461 ccgaagattt caaaacaaaa aaatcgccga tgcttgttaa gtgatctcct aaaagcgacg
    17521 tcaataaccc aaaaggaagc gcgtaaacca attgttgacg cgaagtcgaa aagaagaaaa
    17581 aagtaagcat cagcattcct atagcaatta gagcagtaaa aatccctaaa atcgaataga
    17641 cccatccaat caaaatacaa gaaatcagaa tgactcccgc aaacagatat ttgtatcgga
    17701 tgtgatggtc aatcaataag atacaaattg tgtaaatcaa atattgcaac gctatggacc
    17761 ataaaaacat aaagtacagc tcccattgat ttttaccaaa ttatagcaca attagcgtat
    17821 tattttttta atttttcagg gattttgaat tcagaactca taccaaagca gcagccagat
    17881 acaaaaaagt cagataagtt agttaattgt ttaatgattg tttttttcat gaaagattcc
    17941 tccaaaattc atcaagtagt ttgtaatagg aagcaacgta gctatttcta aaacaatccc
    18001 aagtagcaaa taggtagaaa agtaagaagc tgagaaaaat aaagtaatga gagaaaaaat
    18061 tagaaacatg ctgatcgcct tctttaataa tgggggacgt ttctcgggtt caatgggatt
    18121 gattgctgta cctcttgatc catagcgaag cagtaacaaa aagcagctga ttaacaaaaa
    18181 gaccatcatt gggaaggaga tagtcaattg cagatgtttc atcaccaagg gaacgcccca
    18241 taaataaagt agtgtccaca gcagacaaac gaattcagag tcggaatgca atccataagc
    18301 atatctgcgg atgcatatat aagaaagaaa ggtgattcct gtttccgccc atgagcctgt
    18361 caccagagaa aagactagaa cgaccgctag ttttccaaga ttattcaata aaacttctaa
    18421 ggcaaatttt acttggacat acaccatatc ttcttccgat ttgtctccgc tgaataaggc
    18481 ttctaataat ttgttcacaa ctttatcttt catctcatac gtacctctac cacaaatttt
    18541 atgctaaaaa aaataaaaaa cgtcttttgt ttcataaaaa gtggttttga catcaaaacc
    18601 gtcatgattt cctaaaaaaa tcttcgtttt ccaagaacct taccaaaaaa agtgacagtt
    18661 ttgatacgaa aagtactttt tatgacaagt ttgtgctttt tcgagtgatt tatgttaaaa
    18721 aaattactga ccttataaaa ggtgatggag ggattcttat ggaaaatgaa caattgtttg
    18781 aagtcggcga aacatatgca tttaaatctg atttatttga atcaccaata aaaggaaaaa
    18841 tagaaaaaat ctatgaaaat agtgtgatga tacgtgtcat gaaatgcgca gtagaagaca
    18901 atgataccgc tcataatctg cactggcagt tagttgtacg caaatcaagt acaatagaag
    18961 aataaaaaca gataaaatgt tgagagcata aagaggttgt gagtctccgt ttagctctga
    19021 gttacaagga ataatgttaa aaaacagctt ttcatgtttt atgaatattg ccacttgtga
    19081 ccgaggtgtt ggcaggagaa tactgtttat ttgaaaaaag ggctgcgaca agacttttgt
    19141 cacagccttt attttcatga ataggagtta cttttggcta cttttagaga agtagctttt
    19201 aaggagcaga taaagtcaag gcttttattt ctataaatga agtagtaaaa tgaagaacag
    19261 attttattac aggaaggatg ccgataattg tgatcattgt tgcaggaacg atcggtgcag
    19321 ggaaaagcac actgactgaa atgcttgccc aagatttaga aacaaaacct ttttatgaga
    19381 acgtggaaga taatgaagta ttgccgctat tttattctaa tccagaaaag tatacttttt
    19441 tattacagat tttctttttg aacaaacgct ttttggcaat caaagatgct ttcagccatg
    19501 atgacaatgt actagaccgc tccatctacg aagatagtat gctgtttcat ttgaatgcag
    19561 atttagggcg tgtttctgaa gtagaagtaa agcagtatga aggtctttta gaaacgatgc
    19621 tgaaggagtt agaagaaatt tcgccacaaa agaaaccaga tctactggtt tatattcgtg
    19681 tatcttttga aactatgtta gcgagaatca aaaaaagagg ccgggaatat gaacagctag
    19741 aacaagatcc tgaactctat tcctactata aagaactcaa tcgacgatac gaagagtggt
    19801 atgaacagtt tgatatatgt cccaaaatag tgatcgatgg ggacaaatat gatttcgtag
    19861 ccgatccggc atgtggagaa caaatcgtac aagaaatcaa gatgcgggca aagaaaatga
    19921 cagaagaggc agatgcccag tcgatccgct acactacaaa taacccgaaa gcaaagggaa
    19981 tctttacaac taaataatat aaaaactaag caaattgctc actcgcagat atttctctgt
    20041 gagcagcatc ttgcttagtt tttttgattc attgagatca aatagtgaac cgattcgtat
    20101 gataaaattg ccataaatga aatgtctgag tgagggccat gatcaaaaat aaaatggaaa
    20161 cgatcaaaat cgaatgggcg ccaaacagat gatgacagaa aacaaggaca atagctcctg
    20221 cgataaaggc aagaacgaca cttagatagt ggaaaaatcg atcaaaatct gctttttctt
    20281 tagaaataca ataatcatat aagttcgttg ctaccccttt taaatttcca gttgtaaata
    20341 aattagtgta ggcacgcccg ttgattttat caaaagctac ccactggatc gatgcagtaa
    20401 aagcaatcaa aatcgttact aatgcgggat gctcatggac gggtgtcaaa ctaacaaaga
    20461 aaaaaatcac tgcttcataa tatagaacaa acaagcgcca gaaatgtttt tctttttttc
    20521 taaaataatc aattagatac tttgttagaa gaatccctaa gaaaaagaaa agggtagaca
    20581 atactttttt accaacactt agccattctc cgtcaaatgc ttggatgatc gatagaatga
    20641 tattgccagt ttgagcagag gcaaaagcac catattggat ataagtataa ctgtccatgg
    20701 ctcctccgat aaatgtcagc aaaagtccta ttgtacgccc ctcgtgaaag gaagtctgca
    20761 tttttttcat caccttttat gaatattttt gtcttcctta tcttagcata aacgattgaa
    20821 aaaaaggaaa aattttcaga aaactaaaat catatcgctt cccattttca tttttagaaa
    20881 ggtctgttag tataaagaaa aaatagacaa cgaaacttta aataaccaac ttgaaataac
    20941 caacttgaaa taaacaaatt caaagaagaa agatgggaag gaaatcaatc agttgaatga
    21001 aaaagaaatt ctccgattac aaaaagaatt gaaacgctgg gagaacaagt ataaaaagct
    21061 tcaacaagtc tttcggctac aagaagaaat cattgctacc tatgaagcgg cttatggcga
    21121 agcacccgga cttattgagg aagaagtaca agtaaaagaa agtgaaggaa acagctcttt
    21181 ctttaaaatg atggagaaac gttcctataa tcgcttcaat caagaacaaa aagcagctat
    21241 cacatatgat atgaagaaac atcttcgaat catagcagga gctgggagcg gcaaaacgca
    21301 aacaatctgt gcaaaagctg tttatctgat gacgcaaaaa caagtagacg aagaacgcat
    21361 actaatgatc acttttacaa ggaacgctgc aaatgaacta aaaaaacgag tagataattt
    21421 cagccagaga aaaaccgctg tccatatcgg aacattccat agtatctttt ttaggatata
    21481 caatgaaatt tgtcgaaaat ttcctgaagt agcaatgcaa ggaatacaag gagacttttc
    21541 aaaggatact gcacaaaaag tgaatgctgt tttgcaacag ctgatacgta aatataatct
    21601 ttatatattt gatcaatatg gagaaaaaac gattgcttct cggttagact attggcagaa
    21661 tatgaacctt tcagtagaag aaatggttca gttagttaaa gaaaaatatg attccattga
    21721 taagaatgca cgacagccga tatcagaacg actgtatgga ttgctcacgg aactccaaga
    21781 acaaaaaaga agccagcaat tgctagagtt caatgatgta ctccaaaatc tgaaaagcgc
    21841 tttggagaat gaggagatcc agcattatat cggccaaaaa tatgattatc tattcattga
    21901 tgaatttcaa gatactaatc cacttcaatg ggaaatcgtg aaacggatga caaaggaaaa
    21961 caggatcaag ttgattgttg ttggagatga tgatcagagt atctatggat tcagaggatc
    22021 agagccagca tacatcaaga actttgaaaa agaatatcct accaaaactc ttttcttatt
    22081 aactaattat cgttctcggg cagctattgt ccaaggagca aatagattga tcagctataa
    22141 taaaaatgat cggataccaa aggcgatgat tccagcacaa aaagaagcag gtgttatgga
    22201 agcctatttg ttttctgata ctaaagcaga aagtcagtgg ctaatcaaac aaattcagac
    22261 atttattcaa aaaaatggga aatataagga atcaatcata ttataccgat cagcttcaca
    22321 aacgcagcag cttgtccaat ctctgctgaa aacgaatatt ccttttgtac tggaagcaga
    22381 tagtccatat gaaggtatct ttggtatcaa gtctttccaa catttctatc aaaaaattgt
    22441 tcattggcaa acagcactga atctgcaaaa gaaaaatcag gcctaccagc aattgctccg
    22501 gcagctgatg gcagactgct acctgaaaaa aagtgaatgc gatcaatact tttctcctaa
    22561 atatcaaaat atagccgttg cagattatat tttgtcgata agccccaatt taaaatcaaa
    22621 atctgcagaa atccgagagt ttgaggaagc gttgcgtaaa acagaccagc atcaagaaat
    22681 ctattcgctt gttcaaagct atcttcatct gccacgtata gctaaggaaa tcgaccagag
    22741 tgatcaagaa tggatacgag aagaagtaaa gcagcatgct actttcagaa gactccaagc
    22801 cttatcgcaa gaaacccaag cgacagctaa agaattaaaa acccgcttga ttgcttacag
    22861 acaaggaaaa cttgatgcac tatgtatcca gagcattcac aaaagtaaag gtcttagtta
    22921 ccgaaatgtc tttttgattg gttgtaacga aggaagtttg ccttataacg gagcgacaga
    22981 aaagaaagta atcgacttta atgaaataaa agcagaacca gtgacgacga tagaagaaga
    23041 acgaagacta ttttatgttg cgatgactag agcaagaaat cgtctgtatc tatgtgtacc
    23101 tcaaatgaaa aattcaagaa aattgaaagt atcgagattt atcaaagaaa ccgggagtcg
    23161 tgtgaaaaaa ggaaagtgat agaagagagg gtgtgacaga agtggtcagt ttcaagaaag
    23221 aagaaggaat gtacgaaaat tgcttctcaa atttttgtga aatttcagct tattttcgaa
    23281 gaagctattt ctggaacacc gtttattcgg aaaaaggagg tgtgacaaga attttgtcac
    23341 acctccctta tttattttga aaatgagaat actattatca aaatagagaa tatatagaat
    23401 aattctcatt attcaaacgt aaataatcag tt
//
LOCUS       DAXQKX010000042        23330 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.042, whole genome shotgun sequence.
ACCESSION   DAXQKX010000042 DAXQKX010000000
VERSION     DAXQKX010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23330
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.042"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(242..727)
                     /locus_tag="ACF3MF_001817"
     CDS             complement(242..727)
                     /locus_tag="ACF3MF_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HFE3927803.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    817..1162
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1207..1848
                     /locus_tag="ACF3MF_001818"
     CDS             1207..1848
                     /locus_tag="ACF3MF_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFE3927804.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            1867..2502
                     /locus_tag="ACF3MF_001819"
     CDS             1867..2502
                     /locus_tag="ACF3MF_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFE3927805.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            2520..3335
                     /locus_tag="ACF3MF_001820"
     CDS             2520..3335
                     /locus_tag="ACF3MF_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HFE3927806.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            3654..5090
                     /locus_tag="ACF3MF_001821"
     CDS             3654..5090
                     /locus_tag="ACF3MF_001821"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFE3927807.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            5279..7726
                     /locus_tag="ACF3MF_001822"
     CDS             5279..7726
                     /locus_tag="ACF3MF_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HFE3927808.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            7956..9023
                     /gene="rlmN"
                     /locus_tag="ACF3MF_001823"
     CDS             7956..9023
                     /gene="rlmN"
                     /locus_tag="ACF3MF_001823"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HFE3927809.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            9013..9219
                     /locus_tag="ACF3MF_001824"
     CDS             9013..9219
                     /locus_tag="ACF3MF_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927810.1"
                     /translation="MPNNRILLVFSITIKGAVFLIKELFNLNKRKDSIAKAIKLFLTR
                     KTLIKQRNVLNLMTACLMGVLAII"
     gene            complement(9216..10319)
                     /locus_tag="ACF3MF_001825"
     CDS             complement(9216..10319)
                     /locus_tag="ACF3MF_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFE3927811.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            10872..11420
                     /gene="aac(6')"
                     /locus_tag="ACF3MF_001826"
     CDS             10872..11420
                     /gene="aac(6')"
                     /locus_tag="ACF3MF_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HFE3927812.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            complement(11668..11787)
                     /locus_tag="ACF3MF_001827"
     CDS             complement(11668..11787)
                     /locus_tag="ACF3MF_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HFE3927813.1"
                     /translation="MVFQKPLNNFRYIVYYCHTKIKKNKQKETVTKVLSQSLI"
     gene            11966..13627
                     /locus_tag="ACF3MF_001828"
     CDS             11966..13627
                     /locus_tag="ACF3MF_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFE3927814.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(13697..14044)
                     /locus_tag="ACF3MF_001829"
     CDS             complement(13697..14044)
                     /locus_tag="ACF3MF_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HFE3927815.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            14128..15069
                     /gene="opp3b"
                     /locus_tag="ACF3MF_001830"
     CDS             14128..15069
                     /gene="opp3b"
                     /locus_tag="ACF3MF_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HFE3927816.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            15070..16113
                     /locus_tag="ACF3MF_001831"
     CDS             15070..16113
                     /locus_tag="ACF3MF_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFE3927817.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            16119..17189
                     /locus_tag="ACF3MF_001832"
     CDS             16119..17189
                     /locus_tag="ACF3MF_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3927818.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            17179..18132
                     /locus_tag="ACF3MF_001833"
     CDS             17179..18132
                     /locus_tag="ACF3MF_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3927819.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            18144..19154
                     /locus_tag="ACF3MF_001834"
     CDS             18144..19154
                     /locus_tag="ACF3MF_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HFE3927820.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(19439..20260)
                     /locus_tag="ACF3MF_001835"
     CDS             complement(19439..20260)
                     /locus_tag="ACF3MF_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFE3927821.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(20357..20635)
                     /locus_tag="ACF3MF_001836"
     CDS             complement(20357..20635)
                     /locus_tag="ACF3MF_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927822.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            20903..22912
                     /gene="metG"
                     /locus_tag="ACF3MF_001837"
     CDS             20903..22912
                     /gene="metG"
                     /locus_tag="ACF3MF_001837"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HFE3927823.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
BASE COUNT         7760 a         4070 c         4864 g         6636 t
ORIGIN      
        1 ctgaaatcaa aagaataaaa ttccgattta taatcgaaaa aagaagcatt tttatatatg
       61 cttctttttt cgtagaatca ataaatatgg atttggctaa ctatggaaga atactcgtat
      121 tagttttcag cgttcatact agttgttaca ttgtttgatt ggccaaaaga atttctgata
      181 tattttgtgc taaataaaga aaaagacgct tgaattggga aataagaaaa ctactctatc
      241 attacaaatt ttcataaact ggcagatgtt ctaagtaaac aagtatcttt tcaaagtcgg
      301 aaaaatccat aatcaacgta gtggtattga tatttggatg aaagcctacg gtatcttgac
      361 gatcaatagc agcatcgatc acgacttgga tttttttctc tttgtcgtgc atcaatgcta
      421 atggagtcac tgtacctgct ggaacgccta ggaggtcagg aagctgttct tcagaaacaa
      481 aagataagcg cttttctttt aattgttcag ctagttgttt taaatcggcg tgcttttcat
      541 caggcaagat gacaagatag atttgttttc cttttcttga tttcaataat agatttttta
      601 cttgcggacc aggtagggaa aaagggacat ttttgactga cgtaatcgca ggatgatcga
      661 ctttttgaaa agagataccc agttttttta gtagttcata agcttcttgt tcggttgcac
      721 gactcatcgc gcatcaccct ccttttttta ttagtgtatc ataaaaaaga gttgacaaat
      781 gaaaaataat catgtaaatt acacgtaaag ttaaaacaaa tgacatcgaa aagaagagta
      841 gccgttaggt gtttttagag agtctctggt tggtggaaag aggcagcagt taaccgtgaa
      901 acacatcttg gagtcgattt tctgaagcgt atagtaggaa aatccgggga gcccgttaca
      961 gctgcggtcg ttgctagatg accagataag gctggctttt ccgtgaggag tcggtaaaaa
     1021 aaggtggaac cacgtgatta acgtcctttg atcttcggat caaaggactt tttgttttca
     1081 tctgaacggc aacgactgtg tgaggttttt tctgcaagga aaaaataaac agaggtggaa
     1141 ccacgtataa tacgtcctct tggcatttgc caagaggatt tttttatttt aaaggaggaa
     1201 aagaagatgg agtatttgat tgaagttatg ccgcaattat tagtaggagc actcacaaca
     1261 ttgaaattat ttttatttac cttgattggc tcattaccat tagggattgt tttagcatta
     1321 ggattgtctt tgcattttaa gccgctacgc tacttgcttc aaacatatgt atgggttatg
     1381 cggggaacac cgctgttgtt gcaactgatt tttatttttt atgggttgcc gacgattggg
     1441 atcgtttttg atcgtttcga agcagcactc attgccttta tcttaaacta tgcagcttat
     1501 tttgcagaga tctttcgtgg agggatacaa tcgattcctc aaggtcaata tgaagcagcg
     1561 caagttttgc aattaagtcc ctttcaaacg gtgacgaaaa tcgtcatccc acaagtgaca
     1621 aagattgttt taccttctgt agggaatgaa gttatcaact tggtcaaaga ttcttccttg
     1681 atctatatat taggtttagg tgacgtaatg cgtgctggga aaatcgcgat ggaacgcgac
     1741 gcgactttac tgcctttgct aggcgtggca atcatctatc ttacattgac tggtattcta
     1801 acaatcgtaa tgaaacaagt tgaaggaaaa ttaaattatt accgctaact gataggagga
     1861 agaaatatga ttgaattgaa gaaagtgaac aaagcatttg gtgaaaaaaa aataatcaaa
     1921 gatttgaatc taatcattcc agatgggaaa acattagcta tcgtaggtcc ttccggtggc
     1981 ggtaaaacca cgcttttacg tatcttggct ggcttagaaa gttctgacag cggagaattt
     2041 tatttagacg gtgtaccgtt caacccattc gagcttaaaa tgaaagaaca agttgtagga
     2101 gtcgtattcc aagacttcca gctatttcca catctgaata tttttgaaaa cattacctta
     2161 gcaccaaaaa tggtattgaa acagacaaaa gaagaataca ccaaaaaagc agaagaatta
     2221 gcggcttcat tagggattag tgatttattg aatatctatc cttatcagct ttctggcgga
     2281 caaaaacagc gggtagcgat tgccagagca ttggctatga atccacgggt attggcttat
     2341 gatgaaccaa caagtgcttt agatcctgaa ttacgccagc aagtcgagcg tttgatccta
     2401 tcattgaaag aagatggggt aacccaaatt attgtcaccc atgatttagt atttgcagaa
     2461 aatgtcggtg atcaattact aaaagtttcc ccaattcatt aagaaaggag aagatagaga
     2521 tgaaaaaaac cagttttcta ttcgctttga tcgcaggtct tcttcttttt gcaggctgtt
     2581 cgaacaaaaa aacttcagca gataattggg cgactatcaa cgaagagaaa aaaatcgtta
     2641 taggtttaga cgatacattt gttcctatgg gatttagaga taaagacggg aagctcacag
     2701 gatttgatat tgatttagcc aaagcagtct ttgaacaata tgggattacg gtagactttc
     2761 agcccattga ctggtcaatg aaggaatttg aactgaacaa tggaacgatc gatttgatat
     2821 ggaacggcta ttccaaaacg ccggcaagag aaaagaaagt gcaatttaca aaaccttata
     2881 tggaaaacga tcaagtgctg atcacaccta aagaatcagg aatcacaaac tttggacaaa
     2941 tgaataataa gagattaggt gcgcaaaatg ggtcatctgg ttatgatgta tttacgaaac
     3001 aaccagaagt attaaaagag atagtcaaaa accaagatgc tgttttgtat gatagtttta
     3061 atgaagcatt gatcgatctg aaaagcagac gggtcgatgg tctgctgatg gataaagtat
     3121 acgcagacta ttatttgaaa caaagaaacg aactagaaga cttcaacata acaaaaggtt
     3181 cttatgagag tgaggatttt gcagttggtg cacgcaagtc agatagtaca ttagtgaaaa
     3241 aaatcaatga agccctagat caactagaga aaacaggtga attccaaaaa atatccgata
     3301 aatggtttgg cgaagatgtt acgccgagaa attaacaaat aggggactgt gacaaaagac
     3361 gtgtcacagt ccctttttcc gaataaacag tgttctcctg ccaactcctt gtgactcgga
     3421 gctgaatggc aggctcacaa cctcttggta aacggtgttc aaaagccagt ttttcggtat
     3481 taagccaaat ttatgcaaaa atgtagaaag ccattttcac aaaatttttc ttactactcg
     3541 aaactaagcg actttttcac aacctccttt acatattttt attttgttgt ggaaggggtt
     3601 tcgtgttatt ctaaaagagg aacgattgaa ggttatagga aaggaagaga tgaatggaac
     3661 acaaagaact tacctcattt ccaaaagatt ttctgtgggg ctctgcttct gcagcgtatc
     3721 aagtagaagg agcttggcaa gaagatggga aaggagaatc agtctgggat cgatttgtac
     3781 ggatacctgg aaagacattt aaaggaacga acggtgattt ggcagtagac cactatcatc
     3841 gttataaaga agatattgct ttaatgaaag aacaaggtct gaaagcttac cgcttctctg
     3901 tagcttggac acggattttt cctaatggac gaggagaagt caatcaagct gggctcgctt
     3961 tttatgagag attgatcgac gaattgattg aaaacgatat tgaacctatg ttgactttat
     4021 atcattggga tcttccacaa gcattgcaag atgaatataa tggttgggaa tcacgtcaga
     4081 tcattgaaga tttcactcat tatgcagaaa cattatttga ggcattccgc gggaaagtcc
     4141 attactggat tagtttgaat gaacaaaata tcttcacttc attaggttat ttgttagcag
     4201 cacatccgcc aggtgtgaca gacccgaaac gaatgtatga agttaaccat attgctaatt
     4261 tagcaaatgc atctgtcatc aataaatttc acgagttaga aatgcctgga aaaatcggac
     4321 caagctttgc gtatacgcca aattatccaa ttgacagtaa tcctgaaaat gttctggctg
     4381 ctgaaaatgc agaagacctg atggccaatt attggatgga tgtctatatg tggggaaaat
     4441 atccgattgc tgccatgagg ttcttagaag aaaaaggatg ggcaccaacg attgaagctg
     4501 gcgatgcaga attgctagaa tctgctaaac cagattttct tgggatcaat tactatcaaa
     4561 cggcgacgaa tgcattcaat ccattaaacg gagttggtgc tggaaaaatg aatacgacag
     4621 gaaaaaaagg ttcatcagaa gaaactggag ttcctggaat gtataaaaaa gttgagaatc
     4681 catttgtcga acgaacaaat tgggactggg agattgaccc agaaggatta aggatcggac
     4741 tgcgtcgtat cacaagccgt taccgcatgc cggtactgat tacggaaaat ggcttaggag
     4801 agtatgacaa gttgacagaa gataaacaaa tccatgacga ctatcgaatc aattacttac
     4861 aaagccacgt caaagccatc aaagaagcaa tttcggatgg agcagaagtc ctaggctatt
     4921 gcacctggtc ttatacagat ttgcttagct ggctgaacgg ttatcaaaag cgatatggat
     4981 ttgtatatgt tgatcaagac gaaacacaag aaggatcttt ggaacgatat aagaaagaca
     5041 gttattactg gtaccaaaaa ctgattgaag aaaatggaga gaacctttag ttcacatact
     5101 taaaacaaga aggtacggct ggatatggcc gtgccttttc ttgataaaat catttagaaa
     5161 ttaagaaaaa ctgtaaaata agctgaaaaa tgaaagaaag cgtcagttct ttcaaacaaa
     5221 actttagttc ccttactttt ttttgtataa tgaaacttga tgaaatgagg gataataaat
     5281 ggcacaaaag aaacggccta ctaaaaaaag gaaaaagacg aaaaaaacga aaaagcaaaa
     5341 acagcagcag gaacaaatgc tgacgattgg tgttgggttt gccttgattt tatttgctgt
     5401 cttcggcttt ttaaaattag gttttttagg aatattgatt gcaaacggct ttcggatcat
     5461 tgcaggaaat acttaccaaa tcctctgtct tttattagcc gtattaggat tttggattgt
     5521 cattaagaat acagagtttt caattggtaa aaaccgacgc tggtttggcg gcatactctt
     5581 ttatttcggt atcttattat tgttacatgc ccatttattt ggcaaactcc atactgggga
     5641 accaaatatc atggggacga catgggattt gttagccagt gatataaaac aaagtcaagt
     5701 agacaataac gttggtggtg ggatgattgg agcaatcctt tatcatttta cttacttctt
     5761 gattgcacag cctggaagtt atttagcagc agtgctatta ctggcaggag gagcattcct
     5821 gttcagtaat ctggaaggct atcagctgtt aaatggtatc caatcaattg gagaacgagt
     5881 acaggaatta ttggaaggtg atcctgccaa gcaagctcga aagcaagcgg caaaggaaga
     5941 gagaatgaaa cagcgcgcag aagcgaaaga agcaaggcgc ttagctgcaa aagaagctgc
     6001 agaaaaagaa gctgcagaat atgagaagaa aaaagcggtg agccagcaaa gggaaaatac
     6061 tgctgatgaa tggcaggaac cagaaaatac agagccggag cagctaagtt ttgttccaat
     6121 cgacagtttt caagaaaata tccatcctgc gaatctagag aaaccagtac cagatacacc
     6181 aaaacagacc aatacagcag aaggtttttc agatgagttg ccagaggatg acggtacctc
     6241 attagaattt gagattgaag cagaacagga aaatcaagac tatgaattac cgacagttga
     6301 tttgcttgat tctataccaa ctgtggatca aagtgatgag tataaaaaaa ttgaaaaaaa
     6361 tatcggcgta ttagaacaaa ctttccaaag tttcggtgtc gatgccaagg tcgtcaaagc
     6421 cagcttagga ccatccgtca caaaattcga agtccagccg gctgtagggg taaaagtaag
     6481 taaaattgtg aacttaacag atgatatcgc gcttgcttta gcggcgaaag atgtccggat
     6541 ggaagcaccg attccaggta aatcactgat tggtattgaa gtaccaaatg gaaagatcag
     6601 tatggtttcc tttagagaaa tcatcgaagc acaaccaaac cacccagata aattactaga
     6661 agtaccttta ggacgtgatg tttctggacg ggtacaaacg gctgatcttt cgaagatgcc
     6721 tcacttactc gtggctggtt cgactggtag tgggaagtca gtagcaatta atgggattat
     6781 cacaagtata ttaatgcgtg ctaagcccca tgaagtaaaa ctgatgatga tcgatccgaa
     6841 aatggttgaa ttgaatatgt acaacggcat acctcatctg ttgacgccgg tcgtgacgaa
     6901 ccctagaaaa gcagcgcaag ccttacaaaa agtagtacaa gaaatggaag aacgatatga
     6961 aaaattcgcg gcaaccggag taagaaatat ttctggttac aatgaatttg ttcaacagaa
     7021 aaacttggaa aacggaacga aacatccaac cttaccattc atcgtagtga tcgtagatga
     7081 attagctgat ttgatgatgg tagccagcaa tgaagttgaa gatgcgatta ttcgtttagc
     7141 gcaaatggct cgggcagcgg ggattcatat gatcctagct actcaacgtc caagtgtgga
     7201 tgttatcaca ggaatcatca aagcaaatgt accttccaga atggcatttg cggtatcaag
     7261 cggtacagat tctcggacga tcattgattc taatggggca gaaaagctct tagggcgagg
     7321 agatatgcta ttcttgccaa tgggtgagaa taaaccgatc cgtgtgcaag gagcattcat
     7381 ttctgaccac gaagtagaac gggtcgttca atttgttaca gatcagcaag aagctcatta
     7441 tgaagagaaa atgatgccga cagatgaagt tgaaacgaca ggtgctccag aacagccaca
     7501 agatgagctg tttgaagaag caaaagcact tgtcgttgaa atgcaaacgg caagtatttc
     7561 ccttctccaa agaagatttc ggatcggtta caaccgagca gcacgtttag tagatgaact
     7621 ggaagctcat ggagttgttg gcccgtcaga aggaagcaag cctcggaaag tattcattga
     7681 gcaggaagaa acatcagaaa cgttgccgga cgataatgac atgtaaaact tgtgtgatga
     7741 agggttgaaa aacgaataac caataaaaag acaaggcatg atgataccaa aagaaaaaat
     7801 ggtttttttc catcttttct aatacggtat gatgtcttgt ctttttagtt tttgtgagat
     7861 taaagttcta ttcgatttat ttgtgaagta ttgcattaag gaaatgaatc atgtatagta
     7921 tgtagcgaaa ctttgagaaa aagagggaaa atactttgga aaaacagtcc atttatggct
     7981 tgacgaatga agaattaatc aattggttta tagaaaacgg cgagaaaaaa ttccgagctg
     8041 cccaagtttg ggaatggttg tatcaaaaac gtgtaagtaa tttcacagaa atgacgaatc
     8101 tatcgaaaca attgatcgaa aaattatcgg agcattttat catcaatcct ctaaaacaga
     8161 tggtcgtcca agaagcttcg gatggtacag taaaatattt gtttgaactc cctgataaaa
     8221 acatgattga gactgtactg atgagacaag aatatggctt gtcagtttgt gtgacgacac
     8281 aagtaggatg taatatcggc tgtacgtttt gtgcaagcgg gctgctcaaa aagaaccgtg
     8341 atctgactgc tggagaaatt gttgcacaga tcatgatggt ccaacattat tttgatgagc
     8401 gcaatcttgg cgaacgcgtt tcacatgtcg ttgtaatggg gatcggtgag ccatttgata
     8461 attacgacaa tgtaatggac tttttgcata tcatcaatga tgccaaagga ttggcaattg
     8521 gtgctcggca cattacagtt tccactagtg gattagcaca caaaatcaag gaattcgcta
     8581 ataacggctt gcaagtcaat ctggctattt ccttgcacgc gccgaataat gaggtgcgaa
     8641 catcgatcat gcggatcaac cgaagtttcc caattgagaa attgatggaa gctgtggatg
     8701 agtatttaga gaaaacaaac cgtcgaatca cgtttgaata tatcatgttg aatcaagtaa
     8761 atgatagacc agagcatgcg caacaattag cagatctatt aaaagataag aaaaaattag
     8821 catatgtcaa cttgattcca tataatccag tcagtgaaca tgatcaatat tctcgcagtc
     8881 caaaagctga tgtattgaga ttttatgatg tattgaagaa aaacggcgta aactgtgtga
     8941 tacgtaaaga acatggtaca gatattgatg cagcttgcgg acaattgcga agcaagcaaa
     9001 tgaaaaaaac agttgccaaa taatcgtatc ctactcgttt tttcaattac cataaaagga
     9061 gcagttttct taattaagga actgttcaac ttaaataaga gaaaagattc tatagcgaaa
     9121 gctataaagc tttttttgac aagaaaaacc ctcatcaagc aaagaaatgt cctcaatttg
     9181 atgacagcct gcttgatggg ggttttagca attatttaac tgattttctt atatccttgc
     9241 tggctttctt gtgtagcatg ataagtttct acgtcaagaa tggcctgttt aaatttttct
     9301 cgggtgattt cataaggcac atgtttaata tcatttgttg ccatggcttt atctaagatt
     9361 gcttctaaat cggtcgtgac attgagattc atgtcggtta acgatactgg aagttggttc
     9421 tttttcataa acacatagat tttatcaaac aaatcgaact gctgatccat catcaataag
     9481 gtcagtacac cataactgac agatgctccg tgaaggtatc cctccatttt ttctagaaca
     9541 gtcgtaccgt aatagaatga gtgtgccata gcagaattat agttattgtt aactaaaaca
     9601 gaaaccaatc cggtagtaac aatgatatcc gaaacgactt gttcaattgc atatgaggga
     9661 cgatcgtcgg cactatcttt caatgcttgc gtaccataag tcaagagacg atcaatgcac
     9721 atttttccga tttggattcc taatctatcc gtgtagccta gatcatcgcc acgagcagaa
     9781 aaagtagatt cgacttcttt ggataaagca tcgccaatac ctgcccataa gtatttatca
     9841 ggtgcttcgg caataattgc tgtatcaatg aaggtgtgta caggtggttt tgaaggaaag
     9901 aagagtccgt ccattacgcc ttcttcgtta tagatgacac ataccgcagt gacgggcgaa
     9961 cagttcgaac caatagtggg aaaggtgaag actggtttag ctagtttttc accaatgact
    10021 tttacagtat cgcaagcacg gccaccaccg actgcaaaca ggacgtctgc tttttggaca
    10081 ctttcatgct ggatcaactg ttcaatattt ccataagttg aattaccccc gtaccagaga
    10141 ctggcgacaa cctctatttc ctgtgtcaaa gctactttta ttttgttttc tgcctttgaa
    10201 agtgcagtct tccctccaat cagcactact tttgtcccat attctttgac gattccattt
    10261 gctttttcat acgcatctgt tccaatggta taatttggta agaaaacact ttgactcata
    10321 ttcatttcct tctttcttcg ttgaaacggg ttaaaatttt aaagagtgat cgatctgact
    10381 gcggctgtag atggagtaga ggtgaaccta agacaggata agtgatgaat aaggtggcat
    10441 gaacaccttg aaatcatcaa taagtatcct aaaaacgaac aagtacaaaa acattgaaaa
    10501 cgacaataat gaatttttgt tcctcttagt atttctaccg attccctttg cttttttgta
    10561 attatctaaa aattctaaaa attaagatta ttatatgaaa acaggtttta tttgtcaatt
    10621 cataattggt tttttttaaa gcaaaagata atctatatca tgatgaacaa acagagtttt
    10681 ttcctccaat tgatggcttt cctgatcttt cctattttga ataaagtgtt tctgtataat
    10741 ttttttattt tataagtaag ataaataatg aaagaataga gatactgatt ggtagctaaa
    10801 gatttttgag cgagaacatt tcgttttttc aaaaggactg ttagaataag caagaacaag
    10861 ggggaagacg tatgataatc agtgaatttg accgtaataa tccagtattg aaagatcagc
    10921 tttctgattt actgagactg acttggccgg aagaatatgg agacagctcg gcagaagaag
    10981 tagaagaaat gatgaatcca gaacgaatcg cggtagcagc ggtagaccaa gatgagttag
    11041 taggatttat tggtgcaatc cctcaatacg gtatcacagg ttgggaattg catccattag
    11101 ttgtagaaag ctcccgacga aagaaccaaa taggtactcg attagtcaat tacttagaaa
    11161 aagaagtagc ttccagagga ggaatcacga tttatttagg tacggatgat ttagaccatg
    11221 gaacaacgtt aagtcaaacg gacctgtatg agcatacatt tgataaagtg gcttccatcc
    11281 agaaccttcg tgaacatccg tatgaattct atgaaaaatt aggttataaa atcgtaggtg
    11341 tcttaccaaa tgcaaatggc tgggacaaac cggatatttg gatggcaaaa acgattattc
    11401 ctcgaccaaa ttctcaataa taaaaagagg ttgtgacaga agtaatcagc ttcaagaaat
    11461 aagaaggaat ttacgaaaat tacttcttga atttttgtga aattccaact tatttccgaa
    11521 gaagctactt ttggaacacc gtgtaccaga ggttgtgaaa aagtcgctta gtttcgagta
    11581 gtaagaaaaa ttttgtgaaa atggctttct acatttttgc ataaatttgg cttaataccg
    11641 agaaactggc ttttgaacac cgtttattca gataagggac tgtgacaaga cttttgtcac
    11701 agtttctttt tgtttattct tttttatctt tgtatggcaa taatagacaa tataacgaaa
    11761 attatttaat ggcttttgga agaccatgga aaaccttgta caaagctatt ttttctgaaa
    11821 aattccttga aacctcacga aaaaatcatt attttatgaa aaagacaaaa aaaagtgttg
    11881 attttttaat aattattcat taaactctta aacaacttca gaaaatatta attattctga
    11941 aaattccaat aaaggggtac gtaaaatgaa aaagaaattt acatttggtt tggttgcggt
    12001 atgcggcctt gtacttgctg gatgttatgg cggcagttca gccacaagca gtagttcagc
    12061 aaaaagcggt tcagcagatg gaggaggcgt atttaactta gtcgtgcctc aagaaatgcc
    12121 tacagctgac ttatcagttg caacagatac aatcagtttt acagcattga ataacgttta
    12181 tgaaggaatt taccgtcttg atgaagacag caaaccacag ccggcaggag ctagcgagtt
    12241 ggcagaagtc agtgaagacg gattaactta caaaatcaaa ttacgagaag acgcaaaatg
    12301 gtcaaatggt gatcctgtta cagcagcgga ttacgtttat ggctggcaac gaacagtaga
    12361 cccagctaca gcttctgaat atgcttacct gtatgcgcca gttgaaaatg cagaagacat
    12421 tacagctgga aagaaagata aatcagaact agggatcaaa gcagttggtg actatgaatt
    12481 agaaatcaaa ttgacgaaac aaacaccata tttccaatat ctgcttgctt tcccatcatt
    12541 tttcccacaa aaacaatccg tagtggaaga aaatggggat gcctatgcat ctgcaagtga
    12601 taaagctgtt tataatggac cattcacatt agaagatttt gatggaccag gaacagatac
    12661 agaatggact tataagaaaa atgatcatta ctgggacaaa gatacagtaa aactttctga
    12721 aatcaaagtc agtgtagtaa aagaatcttc tactgcattg aacttattca aagatggcca
    12781 agcagatgac gtgatcttgt ctggtgagtt agcacagcaa aacgcaaacg atccagctta
    12841 tacttctgtt aaagaagcgc ggacaagcta tatcgaattc aatcaacgtg aaaagaattc
    12901 accattcaac aatgtgaacc taagaaaagc tatttcttat tctatcgatc gtgaagcttt
    12961 agtaaaacaa gtactaggtg acggatcagt tgtctctaca ggattgatcc catcagatat
    13021 ggtaaaaagt ccaacaacga acgaagactt tgcaaaagaa gctggaaaat tagtttctta
    13081 tgacaaagat aaagcaaaag aatattggga aaaagcgaaa aaagaattgg gcgttgattc
    13141 tttagaattt gatttgatgg cttctgatga tgattcatcg aaaaaagtaa tcgaatatgt
    13201 tcaaaactca atccaagaaa acttggatgg cgtaacagtc aaaccaacac ctgttccatt
    13261 ctctgtacgt cttgaccgct caacttcggg tgattttgac gcagtactag gcggatgggc
    13321 tgctgactat gcagacccaa gcagctttac tgatttgttt gtcacaggta attcatacaa
    13381 ccgtggtcgc tggagcaatg cagaatatga cgaagcagtt aaagcagctt catcaacaga
    13441 cgctggcgat gaacaagccc gttgggatga tttccaaaaa gcaatcaaga tcatctctga
    13501 tgatatgggt gtcgttccgg tgtaccaaaa agcagaaggt cacctagtga atgaaaaaat
    13561 caaaggtatc gttcaccatg cggcaggcgc ttcatgggat tacaaatgga catacgttga
    13621 agaataatcg ttaataccgt gagcatgaga aaaaacgagg ctgcggcaaa tgtcgcaacc
    13681 tcgttctcat attcacttat cctaacaaag aaaaaagcat gaaaatagca gaaagagcaa
    13741 ttagtattcc ggcaatgatc agccaaaagc tgtacatacc gtagctggca gacgagagcg
    13801 aggaaaattc tggttttttc tttcggttcc ttgttcgtgc aagatggacc gatcgctgaa
    13861 aatgatcgaa gaaacccgaa gaaaagaccc ataaaaaacc gccgataatc agaaacggca
    13921 atgaccataa gaatagatca ttagataatt gaatgagtgt aaaggaatgg ttgatgagat
    13981 tttttattaa aataaccaga atcagtagaa aagctactgc gtaggggata gatttttttt
    14041 tcatttgatt gctcctttat ttttggttca ttatctaata atgtagcgaa acatctgtca
    14101 gaagtcaaaa gctaggggga aacattagtg aatagttata tcaaatatgt attaaaacgt
    14161 gtctttttca tgatcatcac gctttggtta attgcaacaa tcaccttttt cttgatgcaa
    14221 ttgctgccgg gcacgccata tacgaatcag gaacgtttga gtcctgaaac aatcgagatg
    14281 ctaaataaac aagtcggttt ggataaacca gttatcgtac aatatgggat ttatctttct
    14341 aatttgcttc aaggagattt tggaatttcc ttccaattta aaaaccagcc agtcgcacat
    14401 ttgttagctg gaagaatcgg accatccttg cagttagggt tacaggcaat tatctttgga
    14461 acagtcctag ggacgatttt aggaacgatc tctgccatga agcaaaatac atgggcagat
    14521 acatcttcta cactcgtagc gatattaggt cgttccattc caaactttgt atttgctgtt
    14581 ttattacaat atatctttgc aatcaaatta caagttttgc caatcgcaaa atgggatggc
    14641 tttgtgtaca caatcttacc aacaattgcg ttggccatgt cgccgcttgc tgactctgct
    14701 cggtttatcc gtacggaaat ggtggaagta ctgcatagtg attatgtgga attagcaaaa
    14761 gcaaaaggat tgagccgttg ggaaatcgcc tttaaacatg gtcttcgaaa tagtttgatt
    14821 ccattgatga ctttattagg accgttagct gtagcattga tgaccggatc actggtggta
    14881 gaaaatatct ttgctattcc tggtatcggg gaacaattcg ttaagtcaat cacaacaaat
    14941 gattatccta cgatcatggc tgtaacgatc ctttactcat ttatgctgat ttttgttatt
    15001 ttgatcgtgg atctattgta cggtctagtt gatccaagaa ttcgtgtttc agaagggagc
    15061 cgaggataaa tggaaatgat accaaagcgt tatgaaacag ttgcagatat ccctgcggat
    15121 gaatttcttc cattacaaaa aaataccgaa gaagaacgtg aacagattac tgcaccttct
    15181 ttgaatttta tccaagattc atggcgccgt ttaaagaaaa acaaagctgc cgttatttca
    15241 atggttttac tattggtcat cattttgatc tctgtgatca caatctttgt ttctcctcat
    15301 gatccaactg cccaaaacgt ggcttatatc aatttgcctc ctcgtattcc gggaatcaat
    15361 atcgatggat tgaatggaaa agcaatggtt ggtggtgaac ttgttgataa atatgctcaa
    15421 gcaaacgtcc cttcaaacgt aaatttcttt ttaggaacag acggtttggg acgtgatgta
    15481 ttaagccgct tatttatggg aatgagaatc tcgttgctga tcgcatttat tgctgcatta
    15541 ctagatgtaa cgattggtgt agcttacggg ttggtttctg gtttgttagg cggacgtgtc
    15601 gataacgtga tgcaacgttt tttggaaatc ttatcaggaa ttccaaacct cgttgtcatg
    15661 attttgatgt tggtcgtttt tgaaccagga attttttcaa tcgtggctgc tatggccatc
    15721 acaaactgga taccaatggc acgtatcgtt cgtgcacaaa caatgaaatt aaaagatcaa
    15781 gaatatgttt tagctggatt gacattaggt gaatcaagaa tgaaaattgc attcaaacat
    15841 attttgccga atatctctag tgtcattatt attcaaatga tgtttagtat tccatctgct
    15901 attttcttcg aagccttttt aagctttatc ggtttaggtc ttacgcctcc gtcagcttca
    15961 ttaggaacga tgttgagcga agggtacaag acattcctgt atctgcctta tctattatgg
    16021 attccggcag taactttatc ggttatcatg attggcttta acttacttgc tgatggattg
    16081 cgtgatgcct ttgatcctaa aatgaaagag tgaagacgat gacgaaaatt ttagaagtga
    16141 aagacttaga aatctctttt gatacgtatg ctggaaaggt acgagcgatt cgcggtgtca
    16201 attttcattt gaataaagga gaaacattgg cgatcgttgg ggaatctgga agtggaaaat
    16261 cagtgacgac cagaagcatc atgcgcttgc tgtcaagcaa cgccaatata gatgctggtc
    16321 aaatcctctt taaaggtaac gatatcgttg gaaaatcaga aagagagatg caaaaaatcc
    16381 gtggtaaaga aatagcgatg attttccaag atccaatgac ctctttagat ccgacgatgc
    16441 ccattgggaa gcaagtcgct gagtccctta gaaagcataa taaagtttca aaaaaagagg
    16501 gacaaaaagc tgcattagaa ttgcttaaat tagttggaat acccgaagct gagaaacgta
    16561 tcaacagtta tccgcatcag ttctcaggag gtcagcgtca acggatcgtg atcgcgattg
    16621 cactggtatg ttatccggaa atcctgattg ctgatgaacc tacaacagcg cttgatgtga
    16681 ctattcaagc acagattttg gagctgctga aagaaattca gacaaaaatc gatacatcaa
    16741 ttatctttat cactcatgac cttggtgtag tagcgaatgt cgctgatcgt gtcgctgtca
    16801 tgtatggagg aagaatcgtt gaagttggaa catcggaaga aattttctac aacccgcaac
    16861 atccctatac ttggggactg cttggttcaa tgccgacatt agatagtgcg aacgatcgat
    16921 tgtatgctat tcctggttct ccaccggatt tattgaaccc gccaaaagga gacgcattct
    16981 atccaagaaa tgaattcgcg atgaaaatcg atgcagaaca agaaccacca ttttttgaac
    17041 tatcaaaaac acacaaggca gcaacttggc tacttgctcc gcaggcaccc aaagtgacac
    17101 cgccagaaga aatccaacgt cgctgggcta tctttaaaga gaaacaaaaa catacttacg
    17161 gtcaaggagg aattgctgat gccaaataaa ctacttgaag ttaaaggatt gaaacagtat
    17221 ttcaatgtag gaaaaaagaa tgaagtacat gctgtaaatg acatcagctt tcacatttat
    17281 gaaggagaaa cattcggttt agttggagaa tctggaagcg gaaaatccac tactggccgt
    17341 acgatcattc gcttgaatga acctactgat ggtgagatat tattcgacgg tcaagatata
    17401 acgaagatca aagataaaaa aggtttgacg aaattccggc atgatgttca gatgatcttt
    17461 caagatccat acgcttcgtt gaatcctcgt atgaaagtca gagatatcat tgccgaagga
    17521 attgatgtta atggactagc taaatcatct gaagagcgtg caaaaaaagt cgatgatcta
    17581 ttgagaactg ttggattgaa tccaagccac ggtactcgtt atcctcatga attttcaggt
    17641 gggcaacgcc agcgtattgg tattgcacga gcattggcag taaaaccgcg ttttatcatt
    17701 tgtgatgaac caatttctgc actagatgtg tcgatccaag cccaagtggt caatttgttg
    17761 caagatctcc aaaaagaaca tcaattgacc tatctattta ttgcacatga tttgtcgatg
    17821 gttaaacata ttagtgaccg aatcggtgta atgcataacg gcttgttatt agagatggga
    17881 acaagtgatg aaatctataa tcacggtgtt catccttata cagaaagttt gttatctgct
    17941 attcctctac cagatccaga ccatgagaga aaacgcagaa gaatcaaata tcaacctgaa
    18001 ccagatgacg gacaagtacg tcaacttcgt gaaatcgcac cagaacattt tgtctatgca
    18061 actgagcagg aagtcccata ttacgcaaaa aaactaaaac gacaaaagga atctcttctg
    18121 gttgctaact aggagggaca tagatgctaa aagcttttaa attccgtatg tatccgacag
    18181 aagaacaaaa acagcaattg attcgtactt ttggatgtgc tcgatttacc tataaccatt
    18241 tgctgaaaaa gcggcagaaa agttggcaac aaacaggagt agccaatttt tcgctcacac
    18301 ccgctacatt aaaaaaagaa tacccattct taaaagaagt agacagtctt gctttagcaa
    18361 atgcacagct taatttggat cgggcttttc gcaattattt caagggacgt gccagcttcc
    18421 caaagcttaa aacgaaaaaa agtatgtggc aatcttatac gaccaacaac caaacccgta
    18481 cgatctatct ggaaaatggc tacttaaagt taccaaaaca aaaagaacta atcaagataa
    18541 atcagcatcg gccagttgaa ggatcgattc gctccgctac gatttctgct cgatataatg
    18601 aagaatttta tgtcgcacta ctttgtgatg tttcgccagt aaaaaaagaa tctttagcta
    18661 aatggatcgg gatcgcctat catccgaaga cattgatcca aacatctcga cctctagaag
    18721 taactttacc aaaatttcac cagacagaag aaaagctgca acatgcacag cggaaattga
    18781 atgtgaaagt ccgctccgct caccatagaa agatcaggtt agatcaggca agcaattatc
    18841 agaaacaaaa gagaaaagta atggatcttt atctgaaaca aaagaaccag cgagaagatt
    18901 atcttgaaca attatctggg aaattggtca aacaatatga ctacttattt gtagaatctt
    18961 ttccaaaaga agaggcacat gctgattttt ctattcacga ctggcataaa ttaataacaa
    19021 aattgcgtta taagtcccaa tggtataata aaaaatttct tttgatcaat accgacggag
    19081 cagaagaaag caattccgta agaaagagcc aagtagtaga aaaaatgggc agacattcgg
    19141 ttatcaaggg ataaaaaatg aatgaaactg ataggagcgt tagggttagc cttgttaata
    19201 aaaagtctta atgacttttg tttctaggaa tttttctttt gaagaaaagc tcactaatta
    19261 tgacaaacca ataaaacaat agcagaaaaa gttcgtacga gctttttctg ctattgttaa
    19321 ttttttattc agaaagttta cgaatacatc aaaattctga aacaaaaaac gtaactcaca
    19381 aagagttgtt tttgcgtttt ttcttgaatg attaggtctg aatcttttgc tcacaacctt
    19441 attcatggtg ccccggcttg agctgataga tttttgaagg acggccgatt cctacaggac
    19501 gttcaccgat ctcatcgaaa tattggagca tagctttctt aaaattggaa tgatcgatcg
    19561 ttttataatc gatccctaag aatttagcaa atacttttcg agcttccgta atcgtgaaat
    19621 ctttacctaa aacttgtaga acttgcggct cgtgttccat tttattgact acacggttga
    19681 atgctttcaa gatgatttga ctatggtcaa aagccaaagt atctttgcca gaagactctc
    19741 cagtgactaa atcaagcgag atagccactt ctccgctaga taaatggatc ttgttactat
    19801 gacgttctag tgtgaaccag cgtacttcct tggcatcatc tccggcgatt agcggttctt
    19861 ctccaataaa ggctaagtag ctgactgtga cgacccagcc tcgcggatct cgattaggcg
    19921 tactgaatgt atgcagttgc tcaatatttt cttttgaaat aaccacacca gtttcttcct
    19981 ttgtttctct taagacgctt tctccagttg actcatcctt ttggacaaag ccaccaggca
    20041 atgcccatga atttcgataa ggatgccctt ttctttggat caacaaaact ttcagctgat
    20101 cttcttcttt gttatagcac atcagtacga tatcgacagt caaagagggc ttgtcatatt
    20161 ctggacgttc ctgtttttga taccagttaa gaaattcttc ttcacttgct ttatgttcat
    20221 aatataattt ttcttcttct ttagaagcaa aacggttcat ctgaccacct ccattgacag
    20281 taaaagtact ttttacctta ttgtagcaga ctctgaaaaa aaaccaagga tttacttgaa
    20341 aaatctaggt tatcatttaa atatgaaaaa taaatggaag tatgagattg aataaaaaga
    20401 aaagcagata aaacggcaat actttatacc gctcttcacg aatggcaaag aagccacaaa
    20461 taacgatata tacgtcaatg ataaaacgca aaatccaagc tgctgtcata aaactgttca
    20521 aatgcccatg gaggttaaaa taaccataca tacgaatata aaaatagctg aatattaaat
    20581 gtgctaatga aagaaaagca atactaagtg taaaaaaaag atgtttcttc tgcatgattg
    20641 ttccagtccc ttactaagat agatagtctt tattatacca cgtgtgaggg gagaaataaa
    20701 aagccgtttt ttagtagata tgaaacaaaa caaaaacccg catttattca acctattcat
    20761 ccttttaaag gatagattga acgtagatag aagtcgttta tccagtcttt ttcattttga
    20821 aaaaaagcta acagcatgct ttttttatgg tatactagca aggaaacgaa ttcgcatcat
    20881 gcgataaagg aggaagagcc ccgtggcaga aaaggaaact ttttatatca ctacgccaat
    20941 ctattatcca agcggcaaac ttcatatcgg caactcgtat actacgattg catgtgacgc
    21001 aattgctcgt tataaacggt tgatgggctt tgatgtgttt tatctcactg gagtggatga
    21061 acatggtcaa aaaatcgaaa caaaagcaga agaactaggt gtaaaaccgc aagaatatgt
    21121 agataaaatg gcggctgatg tcaagaaatt atggaaaacg cttgatatca gttatgataa
    21181 attcattcgc acgacagatg attaccataa agcagctgtt caaaaaatat ttgatcgttt
    21241 attagaacag ggagatattt acttaggtga atatgaaggc tggtactctg tttctgacga
    21301 agaattcttt acagaaacac aacttgcaga agtgtacaaa gatgacgaag gtaacgtgat
    21361 cggtggtaaa gcgccaagtg gacacgaagt agaattggta aaagaagaat catacttctt
    21421 ccgcatgagc aaatacgcag accgtctatt ggaatactat gaagaacatc ccgaattcat
    21481 ccagccagaa tctcgtaaaa acgaaatgat caacaacttt atcaaaccag gattagagga
    21541 tcttgcagtt tcacgaacaa cttttacttg gggagtacca gtcaagagtg atccgaaaca
    21601 tgtggtgtat gtatggatcg atgcattatc caattatatt actgcactag gatatggctc
    21661 cgaagatgaa agtctattcg aaaaatactg gcctgcagat gttcagatgg tcggtaaaga
    21721 aatcgttcgc tttcatacga tctattggcc aatcatgctg atggcccttg atttgcctct
    21781 acctaaaaaa gtatttgggc atggctggct attgatgaaa gacggaaaaa tgtctaaatc
    21841 aaaaggaaat gtcgtttatc ctgaaatgct tgtggaacgt tatggtttag atgcactccg
    21901 ttattatttg cttcgtgctg ttccgtttgg gtcagatggt gtctttacgc cagaagattt
    21961 tgtttcccgt gtcaattatg atctggcaaa tgatctaggg aacttattga atcgaacgat
    22021 tgctatgatc aacaaatatt gtgatggact cgttcctgac tatgcctcac ttgtcactcc
    22081 atttgatagt gaactgtcta cgacggctgc taacgttgtc ggacgttacc atgatgcaat
    22141 ggaaaaaatg gaattcaata cagcattggc tgaaatctgg gtgctgattt ctcgtgcaaa
    22201 caaatacatt gatgaaacag aaccatgggt attagcaaaa gacgaagaaa agaaagctga
    22261 attgaatagt gtcatgatcc atttagctga atctttgcgt atcgcagcga tattacttca
    22321 gccaatcatg acagaaacgc cagagaagat cttcaatcaa ctaggattgg actctgaaac
    22381 aatgaatctt gaaggattac actttggcga atttccttca ggaacaaaag tagttgcaaa
    22441 aggtacacca atcttcccac gtttagatat ggaagaagaa gttgctttta ttcaagaaaa
    22501 aatgtctgaa ggtactcaaa caaacgaaga tacagtcaaa tgggatccag aagaaacaga
    22561 acttgtttca acgaaagaaa aacaaatcaa atttgatgta tttgaaaaag tagaactaaa
    22621 agtagcagaa gtcatcaact gtcaaaaagt agaaggggca gataagttgc tgcaattccg
    22681 actagatgct ggagacagcc aagaccgtca aatcttgtca ggaatcgctg aattttatcc
    22741 tgatccaagc gaattgatcg ggaaaaaagt cgtcattgta gcaaatctga aaccacgaaa
    22801 gatgcgtgga caaatcagtc aaggaatgat cctttctgca gaagcaccag atggctcttt
    22861 acaagtaatc gaagcaccaa aatccatgcc aaatggctca gaaatcgcat agaaattcaa
    22921 agggggtatg acactagttg tgtcataccc cctttttccg aaatttgaga agcaattttc
    22981 gtaaattcct tcttattact tgaagccaat catataatac agaaacagag aactatccaa
    23041 aataaatcct agaaaaagaa gtacgagctt cgctgatttt tgttaattta gaataatact
    23101 aataggaatc gtaaaaacag aaaaaaagca taatgataaa gggtcgggca gattttaatt
    23161 gattcatctg gtactctttt ttattgtcct tacattcata aagtttgaat gcaatgactt
    23221 tattacatct atatttatat ctaacagtag cgttgatgtg ttaattataa gttctatcac
    23281 tttatgttca attagtttgt gctcttatat gtgtgattga aaatatagat
//
LOCUS       DAXQKX010000043        22900 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.043, whole genome shotgun sequence.
ACCESSION   DAXQKX010000043 DAXQKX010000000
VERSION     DAXQKX010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22900
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.043"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            54..224
                     /locus_tag="ACF3MF_001838"
     CDS             54..224
                     /locus_tag="ACF3MF_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927824.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
     gene            444..1151
                     /locus_tag="ACF3MF_001839"
     CDS             444..1151
                     /locus_tag="ACF3MF_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFE3927825.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(1211..1855)
                     /locus_tag="ACF3MF_001840"
     CDS             complement(1211..1855)
                     /locus_tag="ACF3MF_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HFE3927826.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            1982..2269
                     /locus_tag="ACF3MF_001841"
     CDS             1982..2269
                     /locus_tag="ACF3MF_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927827.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            2377..2697
                     /locus_tag="ACF3MF_001842"
     CDS             2377..2697
                     /locus_tag="ACF3MF_001842"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFE3927828.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            2778..4091
                     /locus_tag="ACF3MF_001843"
     CDS             2778..4091
                     /locus_tag="ACF3MF_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HFE3927829.1"
                     /translation="MNHFWGRRLLTRDIKAIDCEEVNLPNYEKIAAVERLGNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEIAKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKML"
     gene            4088..4807
                     /locus_tag="ACF3MF_001844"
     CDS             4088..4807
                     /locus_tag="ACF3MF_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HFE3927830.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVKSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQVAQPKIIRTISLAR"
     gene            4935..5486
                     /gene="raiA"
                     /locus_tag="ACF3MF_001845"
     CDS             4935..5486
                     /gene="raiA"
                     /locus_tag="ACF3MF_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HFE3927831.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADATALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            5708..8242
                     /gene="secA"
                     /locus_tag="ACF3MF_001846"
     CDS             5708..8242
                     /gene="secA"
                     /locus_tag="ACF3MF_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HFE3927832.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPHHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKSFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            8368..9469
                     /gene="prfB"
                     /locus_tag="ACF3MF_001847"
     CDS             join(8368..8439,8441..9469)
                     /gene="prfB"
                     /locus_tag="ACF3MF_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HFE3927833.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            9574..10260
                     /gene="ftsE"
                     /locus_tag="ACF3MF_001848"
     CDS             9574..10260
                     /gene="ftsE"
                     /locus_tag="ACF3MF_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HFE3927834.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            10253..11137
                     /gene="ftsX"
                     /locus_tag="ACF3MF_001849"
     CDS             10253..11137
                     /gene="ftsX"
                     /locus_tag="ACF3MF_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HFE3927835.1"
                     /translation="MIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFMAVI
                     MNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELKKIQ
                     NEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSDRIF
                     QIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRWPFF
                     LEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMVGIG
                     VIIGSLGSIISMRRFLKF"
     gene            11289..12737
                     /gene="cls"
                     /locus_tag="ACF3MF_001850"
     CDS             11289..12737
                     /gene="cls"
                     /locus_tag="ACF3MF_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFE3927836.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWVLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHSTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            13074..13931
                     /locus_tag="ACF3MF_001851"
     CDS             13074..13931
                     /locus_tag="ACF3MF_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HFE3927837.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            14046..14966
                     /gene="pstC"
                     /locus_tag="ACF3MF_001852"
     CDS             14046..14966
                     /gene="pstC"
                     /locus_tag="ACF3MF_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HFE3927838.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            14966..15850
                     /gene="pstA"
                     /locus_tag="ACF3MF_001853"
     CDS             14966..15850
                     /gene="pstA"
                     /locus_tag="ACF3MF_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HFE3927839.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            15865..16671
                     /gene="pstB"
                     /locus_tag="ACF3MF_001854"
     CDS             15865..16671
                     /gene="pstB"
                     /locus_tag="ACF3MF_001854"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFE3927840.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            16687..17445
                     /gene="pstB"
                     /locus_tag="ACF3MF_001855"
     CDS             16687..17445
                     /gene="pstB"
                     /locus_tag="ACF3MF_001855"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFE3927841.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            17458..18135
                     /gene="phoU"
                     /locus_tag="ACF3MF_001856"
     CDS             17458..18135
                     /gene="phoU"
                     /locus_tag="ACF3MF_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HFE3927842.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            18712..19404
                     /locus_tag="ACF3MF_001857"
     CDS             18712..19404
                     /locus_tag="ACF3MF_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HFE3927843.1"
                     /translation="MLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLLNISIL
                     FVVIGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYL
                     TRPYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVI
                     GSMTNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPIS
                     VLFFLTVRRLKR"
     gene            19401..20168
                     /locus_tag="ACF3MF_001858"
     CDS             19401..20168
                     /locus_tag="ACF3MF_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HFE3927844.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            20268..21836
                     /gene="liaX"
                     /locus_tag="ACF3MF_001859"
     CDS             20268..21836
                     /gene="liaX"
                     /locus_tag="ACF3MF_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HFE3927845.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEIAQVQL
                     STTTGSIYLKDTDK"
     gene            22133..22453
                     /locus_tag="ACF3MF_001860"
     CDS             22133..22453
                     /locus_tag="ACF3MF_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0080135 - regulation of cellular response
                     to stress [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HFE3927846.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            22453..22803
                     /locus_tag="ACF3MF_001861"
     CDS             22453..22803
                     /locus_tag="ACF3MF_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HFE3927847.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
BASE COUNT         7535 a         3934 c         4933 g         6498 t
ORIGIN      
        1 ttctgctgat ttaagataga gttaagttaa ctacaagaat tggagggatc cacatgaaat
       61 ggaaagaaaa agtagacgaa gcagctgaaa agttatatga tttggtcaaa tcagaaaaat
      121 acaatattga agtgaatatt ccgaaaaaag gcggaaaagc ggtccaggta aaatcaaaac
      181 gcccaacgaa tcatacaaaa aaatggatgg ctaaaaaccg ctaataataa caaaagatcc
      241 ataagtcggc attttcatcg attttagggt cttttgttat tttctaggtt gaacatatct
      301 aaaaaattgt ttctgacaat aggagtagga agaacgatgt gtgtctaaat cctctgttga
      361 tggatagaaa cctttatctt tttcagttgt gaatcaggta tataccagtt ataatagaag
      421 aaacgaaagg acgggtgtac gttatgtcga atcaattacc tgtatatata cagattcatg
      481 accaattaaa aaatgaaatc gaacaaggta tatggaaagt cggagaccgt cttccttcag
      541 aaagagaatt agcagtgaaa ttcaatgtca gccgtatgac gttgagacaa gcaattcaaa
      601 acttggcaga tgaaggaatc ttagaaagaa agatcggttc gggtacatat gttgcgcgag
      661 aaaaagtaca agaaaaaatg tctggtgcaa caagttttac agaaattatg gaatcgcaaa
      721 atcgagtacc gtctagtcgg acaatctctt atttcttgac ttcgccaagc tcaagtgaaa
      781 tggaaaaact aaacttgagt aaagatgaca cgatcttgcg aatggaacgt attcgtttcg
      841 cagatgatgt ccctatttgt tttgaagttg ccagtgtgcc acaaaagctg atcgatggct
      901 acagcaaagc agagattact gaatcgttgt atcgcacgct agaagaaaaa ggcgggaaaa
      961 agatcggtcc agcgaatcaa acgattactg ctgtgttggc ttctgagaaa attgctgact
     1021 atttagaggt aaaacgagga gatgcagttc ttcgtttgcg ccagatttct tattttgaag
     1081 acggtacgcc gtttgagtat gtgcgtacgc aatacgtagg aaatcgtttt gagttttatt
     1141 tggaaaaata aaaaacaggt gatccctgat tccttactta gaaataaaag agaatcagaa
     1201 tcacctgttt ttatatatga tcagttacca gttgctcgtg ataagaaaca ggaccctctt
     1261 caaattggac ttgtccgttc agcagctcaa tgatggattc tttaaagtgg tcagcacttt
     1321 tttcatctac agcacagatg acgctaactt gatcagtata ttggatttct tttataaaaa
     1381 aatgttggag ttcaagataa ttctgtaatt ttcctagttg cggatacgtg atcatcacag
     1441 agatctcctg ttgcaaggta ccttctacga ttccaatgtc agacaatgct tgagagacag
     1501 catgagtgta tgctcgtatt aatccgcctg tgccgagttt cgttcctcca aaatatcgag
     1561 tgactactgc agctacattg atcagttgat tttttttgag gacttccaac atcggtacgc
     1621 cagccgttcc acttggttct ccatcatcgc tgcttcgctg gatttcattt ttttctccaa
     1681 tgatgaaggc gctgcagtta tggttcgctt tccaatgttc tttttttatt tcttgaatga
     1741 aactttttgc ttggtcctct gattctattc gtctaagaga acagataaag cgtgattttt
     1801 tgatctcaat ctcactttgt ccattttctt ttattgtacg atagcgctcg atcatcttgt
     1861 cacctctttt tttcattttc tttattcagt ataaataaag ttctaggttg tttcaacact
     1921 gtaacggttg cgcaatcgct gtagtatgcg ataataaaga caaaggtagg tggatctggg
     1981 gatgcaggaa cgaatgaaaa agtacgatgc aattacgcat tatttgaaga acaatggcgg
     2041 ctctcaagta acgttgacct ttacccaatt tgacgaactg ctgtttccca gtaacggact
     2101 tcccaaaaca gcaagggaaa gtacagattg gtgggcaaat gattataaac accctgaaaa
     2161 aggtgcctat ggctggataa atgcaggcta tgaagtagtt gtcatcaatt tggacaaaga
     2221 atatgtcgtg ttcaataaat tagtgaaatc tagttggcta tttgattaaa taaaccgcgt
     2281 ttagaaaacg ttgacaaatt tctttctttt tatataatag agtaacagac gcgaagaaaa
     2341 cgtttgcgta gtttgtttta aaaaggagag aaaagtatgg ctaaaaaaac aatcatgctt
     2401 gtatgttcgg ctggtatgag cacaagttta ctagtaacaa aaatgcaaaa agctgctgaa
     2461 gcaaaaggaa tcgactcgga tattttcgct gtgtccgctt ctgacgcaga taacaatctt
     2521 gcaaataaag atgtagatgt actgttatta ggacctcaag ttcgctttat gaaagctgat
     2581 tttgaaaaac gtctggaacc aaaaggcatt cctttagacg tcatcaatat ggctgattat
     2641 ggtatgatga atggcgaaaa agtgttagat caagcaatca cgctcatagg tgaataaata
     2701 gaacagtata actatcgaac aagcgatcca aaaaatagat cgcttgtttt ttcgtatatt
     2761 tttttagggc gaataatatg aatcattttt ggggtagaag gcttctgacg agagatatta
     2821 aagcaataga ctgtgaggag gtaaatttac caaattatga gaagatcgca gcagtggaac
     2881 gtttgggcaa ctggattctt tgtcatcgct gtggaatgag gacgtccgtc attgatggac
     2941 agcttgcaga ttacggttat ttttgtacac attgtctata tttagggcga tgcgacactc
     3001 aacaagattt atatttgttt gatcagcctg aagcaaaacc tcgagaagtc gtcttttttt
     3061 ggacaggaca gcttactgaa aaacaaacgg aaatcgcaaa gagaatactt tgccattcag
     3121 aaaaaagaca tcatcttatt tgggctgtaa caggtgcagg gaaaacagag atgctttatc
     3181 ctattttagt ggaaacttta aaagctggag gaagagtagc gatttgtaca ccgcgagtcg
     3241 atgtttgtaa tgaattgttt ttacgctatc gttatgtttt tccagaagaa aaaatcacgt
     3301 tgctccatgg gaatacagca acggcttata cctttacttc ttttgttatc tgtacgattc
     3361 atcagctata ccgtttttat cggtcctttg atttaatagt gatcgatgag atcgatgcgt
     3421 ttccttataa cggggatgca ggattagctc atgctgtgca aacagcgatt aaaccagacg
     3481 gacgattcat ctacttaagt gccacacctg ataaaaagtt actaaaggaa atcaagcaga
     3541 cgtttgacat ccacaaactt gctttgcgct ttcatcggcg tttacttcct gaacccgtct
     3601 tggttttcat gaataattgg cgacaaaaat gcaagaacaa gaagaagata aaatctttgg
     3661 tgcggatcat tcatcaatta attaaagaaa accatatcct tttattttgt ccaagtatca
     3721 cgatgatgca tcgtttgaaa gccacacttc aagaggctct tccgagatat gagatcacag
     3781 atgtttcttc aagagacaat cagcgggcgg aaaaagtcca gaaaatgcga gaagcaaaat
     3841 atgacatact gttaaccacg atgatccttg aacgtggagt cacatttgaa agaatatccg
     3901 ttatcgtttt aggagcggat catccggttt ttactaaatc ttctttggta caaatcgcag
     3961 gaagagccga tcgtaaaggg ccttatacga acagtcaagt atactttttc tatgaagaaa
     4021 aaactgcagc tattcgaaaa gcttgtcagg aaatcaaaga aatgaatgaa gaagggaaga
     4081 agatgctgtg aggtgcagtt gctgcagtaa agatatcgtc caaaatttaa cattcagcga
     4141 gattattggt gtttcgaaat acagattacc tcagacttgt tcagtttgtc gcgcacaatt
     4201 tcatttattg gaaacaagag gctgttctgg ctgtcaaaaa ccaatccatt tcaatctaga
     4261 gagtacgaaa aagaaagtaa agtctattcc cgtttactgc agtgactgtc aagaatggaa
     4321 gaagaaatat ccgacctatg attttcagca ccgtgccttt tttgtgtacg atgaaaatat
     4381 gaaggcctgg ctcaatcaat acaagtttat gggagatatc cgactagcag gcacctttgc
     4441 atataaatgg acgcagataa aaaaagaata cccgacatac atctattgtc caataccttt
     4501 atctgaaaaa aggcgaacag aaagaggatt caatcaagta agcgagatgt tgaaagcagc
     4561 aagaattcct tttcagatgc tactcaaaag agagaagcat ctgctggctc aagcaaaaaa
     4621 cacgcgaaag gaaagattgg agatgcctca accttttgaa cttgcagtca ccttttctaa
     4681 gatacaaaat aaaaaaatat tgattattga tgatgtctat acaacaggac agactctttt
     4741 ccacgcagca gattgtttgc aggtcgcaca gccgaaaatc atccgaacca tttctttagc
     4801 aagatgaatt agatgtggaa atttgatagc gatttaattt gcaaataacc tagagttcga
     4861 tataatagaa ttaagaagag ggaaagagtg gtccttctcc ttcttgattg tggtagacga
     4921 aaggggtaat ttttatgttt agatataatg tacgcggcga aaatatcgaa gtaactgaag
     4981 cgattcgcga ctacgttgag aaaaaagtag gcaaactaga acgctatttc agtgacgcac
     5041 ccgatgcaac ggcgcatgtg aacttaaaag tttatacaga aaaaacagca aaagtggaag
     5101 taacgatccc attaccttat cttgtattac gtgccgaaga aacttctcca gatttatacg
     5161 caagtatcga tttggttgtt gacaaattgg aacgccaaat ccgcaaattc aaaacaaaaa
     5221 ttaatcgtaa atcccgtgaa acgggcatga atactgcaga tgctactgct ttattcaatg
     5281 aagaggacga aaacgaaaat gattctgaat tagatatcgt acgtacgaaa cgcctttcat
     5341 tgaaaccaat ggatagtgaa gaagcagtct tacaaatgaa catgctggga cataacttct
     5401 ttatttttga agatgcagaa acaaatggta caagtatcgt ttaccgccgt aaagatggaa
     5461 aatacggact gattgaaaca gactgatcag ccttacttaa ataacaacga aaacttgcag
     5521 cagctactga cagctgccgc aagttttttt gagtttcctc ctcttttaga tgaaatatga
     5581 ataaattatg aagttcttac tttaatacgc ttaagatatt tcaattatct ataactaatg
     5641 ataaaatgaa aagtaaagtc tacatagtct ggataataca cagaaggaaa aggagattac
     5701 acaacgcatg gccaatttga ttcgttcact tatcgaaaac gataagaaag aactaaaacg
     5761 tttagatagc attgcaaaaa aagttgaagc atacgctgac caaatggcag cattaactga
     5821 tgaacaatta caggcaaaaa ctgctgaatt caagggcaga taccaaaaag gagaaacatt
     5881 agatcaatta cttccggaag cttttgcagt cgtccgagaa gcagcaaaac gtgtattggg
     5941 gttatatcca caccacgtac aattgatggg tggaatcgtg cttcacgatg gaaatatccc
     6001 tgaaatgcgt actggtgaag gtaaaacctt gaccgcaacg atgccagtat atctaaatgc
     6061 tctgactggc gaaggggtac acgtagttac cgtcaatgaa tatttagcaa cccgtgactc
     6121 gacggaaatg ggcgaacttt ataatttctt aggattaaca gtggggttga atatcaactc
     6181 aaaatcttcg gatgaaaaac gcgaggctta taattgtgat atcacttata gtacgaataa
     6241 tgaattagga tttgactact tgagagacaa tatggtcgtt taccgccatc aaatggtaca
     6301 acgtccgctg aattatgcca ttgtcgatga agttgactca atcttgattg atgaagcgag
     6361 aacgccgctg atcatttcag ggcaagcaga aaaatccaca gctttatata caagagcaga
     6421 caacttcgtg aaacgtttga aagaagaaga agattataaa atcgatgtac aatcaaaaac
     6481 aatcagttta accgaagcag ggatcgaaaa agcagaagaa acattcggtt tggataactt
     6541 atacgacatt gaaaatactg cattgaccca tcacttggat caagcattga gagccaacta
     6601 tatcatgctt ttagatatcg attatgttgt ccaagacgga aaagtactga ttgttgacca
     6661 gttcactggt cggatcatgg atggacgccg ttattcagat ggacttcacc aagcaatcga
     6721 agctaaagaa ggcgtagaga tcgaagacga aacgaaaacc atggcgacga tcactttcca
     6781 gaactatttc cgtatgtaca agaaacttgc gggaatgact ggtacagcta aaacagaaga
     6841 agaagaattc agagaaattt ataacatcca agtataccag attccgacaa atcgtccggt
     6901 tatccgtgat gatcgtccag atttgcttta cccaacatta caaagcaagt tccacgctgt
     6961 cgtgcaagat atcaaagatc gctaccgcaa aggtcaacct gtgttagtcg gaactgttgc
     7021 ggttgaaaca tctgagttat tatcagatat gctgaatcaa gaacgtattc ctcatgaagt
     7081 gctgaatgcg aaaaatcact ttaaagaagc agagatcatc atgaatgctg gtcaaaaagg
     7141 tgctgtgacg attgctacca acatggctgg tcggggaaca gatatcaagt taggacttgg
     7201 ggtaagagaa cttggtggtc tagcagttat cgggacagaa cgacatgaat ctcgtcgtat
     7261 cgataaccag cttcgaggac gtgcaggacg tcaaggagac cctggtatgt cacagttcta
     7321 cttgtcattg gaagatgatt tgatgaaacg attcggttca gaacgaatca aatctttctt
     7381 agatcggatg aagatcggtg aggaagatgc tgttatccaa agcaagatgc tgacgaaaca
     7441 agtagaatct gcacaaaaac gtgtagaagg aaataactat gacacacgta aaaacgtctt
     7501 acaatacgat gatgtgatgc gtgaacaacg tgaagtaatc tataaacagc gacaagaagt
     7561 aatcatggaa gaaaaaagct tatccaagcc actaatgaac atggtcaaac ggacaatcag
     7621 tcgtgtagta gatgcgcata cacaattaga gaaagaaaat tggaatttgg aaagtatcat
     7681 cgattttgcc ggcagtactc ttgtccatga agatagtatt actcttgcag atatcgaagg
     7741 aaaaacagct caggagatca aagagtatct aaacgaacga gcacaagaag tatttaatac
     7801 caaagcggct caactaaatg gtccagagca actgttggaa tttgaaaaag tcgtgatctt
     7861 gcgtgttgtg gactctaaat ggacagacca tattgatgca atggatcaat tacgtcagtc
     7921 aatcggctta cgtgcttatg gacagaacaa tccattagtc gaatatcaaa cagaaggcta
     7981 taagatgttt gaagatatgg taggcgccat cgagtatgaa gtcactcgaa tctttatgaa
     8041 agctgagatc cgtcaaaacg tacagcgtga acaggtttct caaggaacag cttctcactc
     8101 agaagacgga gatgccaaag aaaatagtaa tactagcgcg aaaaaacagc caatccatgt
     8161 gaacaaggtc ggaagaaatg atccttgtcc ttgtggaagc gggaaaaaat ataagaactg
     8221 tcatggaaaa aatgcaaact aatttctgac agcaggattg gtgagacaaa ttcttttttt
     8281 aagaattcgt ctcaccttct ttctgttatt tgctgattct gttagactag atataatgaa
     8341 aaaagtatag tgaaagaagg aaaaaacatg gaaatatccg aaattcgaaa tctcctgaca
     8401 gaaatgcagg aaaaggtcac aagcttcagg aggtctcttt gacttagacc agctggaaga
     8461 agacattgcg gaagcagaag caaaaatggc tgaacctggt ttttgggatg atagcgaagc
     8521 tgctcaaaaa gtgatcagtg aaaacaatgc aaataaagaa acttatgatc aattccattc
     8581 tcttgctgaa gaactggaag aaatcgaatt gatggtggag atgttgcagg aagaacctga
     8641 tgcagccatg caagaagaag cagaaacacg tatcaatgcg ctagatgaaa aaatgaagac
     8701 atatgaatta tctatgttgt tagatggtcc ttatgatcga aacaacgcca tcgttgaatt
     8761 gcatccaggg gctggcggaa cggagtccca agattggggc agtatgcttt tacgtatgta
     8821 tacacgctgg gcagagcagc atgggtatca agtagagaca ctagattatc aagcaggtga
     8881 tgaagcagga atcaagagtg tgaccctact gatcaaagga cacaacgcat ttggttatct
     8941 gaaatcagaa aaaggtgttc atcgccttgt acgtatctcg ccttttgact cagcgaaacg
     9001 acgtcatact tctttttgtt cggtagatgt gatgccagag cttgatgaaa cgatcgatat
     9061 agaaatcaat ccagatgatt tgaaaatcga tacgtaccga gcaagtggtg caggtggtca
     9121 gcacatcaat aaaacagaat ctgctgtacg gatcactcac ttgcctacag gaacagtagt
     9181 agctagtcag gcacaacgtt cacaattgaa aaaccgtgag caagcgatgg ggatgttaaa
     9241 agctaagctt tatcaattag aagtggaaaa gaaagaacaa gaagcagctg cacttcgagg
     9301 agaacaaaaa gaaatcggct ggggttcaca gatccgttct tatgttttcc atccatattc
     9361 tatggtaaaa gaccatcgga caaacgtaga gacaggaaat gtccaagcag ttatggacgg
     9421 tgaccttgat ttatttattg acggctattt aaaaatgcat ctacaataag aacccattgt
     9481 taaattgaaa taaaattgta agattttgca agcatgttga aacattgcca tgctataata
     9541 gctaaagact gaaaaagata tggagagaac gccatgattg aaatgaagga tgtaatgaag
     9601 aagtactcaa atggtacgac cgctatccgc aatctctcaa ttgtcatcga acaaggagag
     9661 tttgtctatg tggttggtcc gtctggagcc ggtaaatcta cattcatcaa attgatgtat
     9721 cgagaagaaa aagcttcaaa aggaactttg aacgtcgcag gtcatgatct aatagcaatc
     9781 aaaaaccgcg aagttcctta tctacgcaga gaaatcggcg tggtgttcca agactataaa
     9841 ttattaccaa gaaaaacagt atatgaaaat gttgcgtacg ctatgcaagt tatcggcaga
     9901 aaacctcggg atatcaaaaa acgagtaatg gaagtgctgg accttgttgg tttgaaacac
     9961 aaagttcgag tctttcctag cgaattatcc ggtggggaac agcaacgtgt ctctattgct
    10021 cgggcaatag tgaatacgcc taaagtactt atcgcggatg aaccgacagg aaatctggat
    10081 ccagaaaact catgggaaat catgaaatta ttagatcgga tcaatgccca aggaactact
    10141 gtcgtgatgg ctacacataa cagtacgatc gtaaatacga ttcggcaccg agtaattgct
    10201 atcgaaaacg gccgcattat tcgagatcaa gcggaagggg aatatggata cgatgattag
    10261 aacctttttc cgccatttat tagaaagtat caagagtttg aaacgtaacg gctggatgac
    10321 agttgcttca gtcagtgcgg taacgatcac attgacttta gtcggtgtat tcatggcagt
    10381 tatcatgaac gcaactaaat tagctcaaga tatagaagga aacgttgatg tctctgtatt
    10441 cgtagatatc ggtacaaaag acgaagagat gaaaaagcta gaaaaagaat tgaatgactt
    10501 agatcatgtt aaaaaagttg aattttcaag caaagaacag gaattgaaaa aaatccaaaa
    10561 cgaaatgggt gattcctgga aattgtttga aggtgacaat aacccgttat atgatgtgta
    10621 tgtagtaagt gctactgatc cttcttatac aaaacaagta gcagaagaag cagcagattt
    10681 gaagaatgtt tctcgttctg attacggtgg agcttcctca gatcggattt tccaaatcgc
    10741 tggtgcagtt cggacatggg gattagttgc agcggcattg ctgctgttcg tagcgatgtt
    10801 tctcatttcg aacacgattc ggatcacgat tttgtctaga cagcgtgaaa ttcaaatcat
    10861 gcgtttagtc ggtgcaaaaa atggatatat tcgctggccg tttttccttg aaggtggctg
    10921 gatcggtctg atcggtgcga ttcttccgat tttgatcatc acatttggtt atgcatggtt
    10981 tttccaattg atcaatccat cattattacg ttcccattat tcattgattc atccacaaaa
    11041 tatcgtttgg aaaatcaatc ttttaatggt cggcattggt gtgatcattg gttcacttgg
    11101 ctcgatcatt tctatgagac gtttcttgaa attctaatac cacaatataa ataaaatgag
    11161 aaagttggac agtttcgttc cagctttctt tttttattgg ctaggagaat agaaggaagc
    11221 ggcttttttc cctttacttt aaaaaacaac ttgggtattc ttaagttggt agaagaagag
    11281 gtgaagccgt gaaaattatc gttgacaatt tttttacgat ccttttgatt atgaatattt
    11341 tgctttcctt tatcatcgtt tttcgagaaa gaaaggaaac tgctcaaaca tgggcatggg
    11401 tgctcgtttt gatgttcatt ccagttgtag gatttatttt atatattttt ttaggaagag
    11461 ggatttccaa agagaaaatc tttgatttga agatccaagg gaaaatcggt aagaacctgg
    11521 aaattgaaga agacaaacag gcattgatgc gagggcttta tcctcatccg cctactggac
    11581 aagtagatgt gaaacaattg atctatatgc tcacggtatt tgaaagtacg ctctatacga
    11641 ctaaaaatga aatcacttta tttacagatg gtcgtgaaaa attcgatgcg ctgattgaag
    11701 atatcaagca ggcagaagac catatccact tccagtatta tatttatcgc agtgatgcat
    11761 taggtgaaga agttcgagat gcattgacag aggcggcaag acgaggggta aaagtcagag
    11821 tccttcttga tgcatggggt tccacacaag tttcttccag cttttttcag aatttgaaaa
    11881 aagcaggcgg agaagtcgca tttttctttc ctctatttgt tccgtatatt aatcctcgga
    11941 tcaattatcg caatcatcgt aaaatcgtag ttattgatgg gaaaatcgga tatacaggtg
    12001 ggttcaatgt tggaaatgaa tatctaggat tggtaaagaa atttggttat tggcgagaca
    12061 atcatttgcg tatttacgga gaagcggtgt ataccttgca aaaccgtttt ttgatggact
    12121 ggaattctca gcatacaaaa gaagtaggct attctcccaa attttttccg tccattcact
    12181 ctactggtga tatagctgtt caaatcgtga caagcggacc agataccgaa catgaacaaa
    12241 tcaaaatgac ttatttgaaa atgatttcgt tagccaaacg ggagatattg atccaaacgc
    12301 cttattacat accggatgga tcgattcatg aagcactgaa gttggctctt ctttcaggcg
    12361 taaaagttca tatccaaata cctaacaaac cagatcatct tctcgtttac tgggcaacgt
    12421 attctttcgc tgcagagcta atcgagtatg gagcaaggat cgaaacatat gagaatggat
    12481 ttattcatgc aaagacgatg attatcgatg gtggcattgt ttcagttggc tcagcaaata
    12541 tcgatgttcg ttcatttcgc ttggactttg aggtcaatac actggtttat gatgaacgaa
    12601 tggcttcacg tgtaagaaaa gctttttttg aagactcgaa aatttctacg catctcacaa
    12661 aagaaatgta tgaaaaccga ggaataatca tcaagatgaa agaaggatta gcaagattga
    12721 tttcgccgct cctttaaaac ataaaaagga catgagaacc atcaacagat ggagatctcg
    12781 tgtccttttc taacggggcc atttctgaga gtacgtcaga aatggagaaa gcgtctcgca
    12841 tgagcgaaat taactttggg gtatctcttg ttttttgggg aaagcaagaa ataagctaat
    12901 atatgctatt aaaagagaca catttcaaag ccagtatagc atagaaactt ttaatgagat
    12961 agtttttttt acaattatga gaatttattt tgttatttaa tgattttgat tcgttttcat
    13021 caagtaatga aaatgataaa ataaacatac tttaggatta aaggagattt ctaatgaaaa
    13081 aacttaaatt attcttacca ataataggat tagctattct tttatcaggc tgttcaaagt
    13141 ggattgatcg aggagaatcc attacggctg ttggctcttc tgctttacag cctttagtag
    13201 aaacagttgc tgaaacttac cagacagaaa atcctggaaa attcatcaat gtacaagggg
    13261 gcggaagcgg aactggtttg tctcaagtac agtcaggagc agtcgacatc ggaaactctg
    13321 atttgtttgc ggaagaaaaa tcggggatcg atgcctcagc attagtcgat catcgagtag
    13381 cagttgttgg gatcactcct attgtgaaca aggatattgg cgtaaaagac atcagtatgg
    13441 aaaacctgaa aaaactattt acaggcgaga tcaaaaactg gagtgaagtc ggtggaaaag
    13501 atcagccagt agttatattg aaccgcgctt caggaagcgg aacccgtagc acgtttgaaa
    13561 aatgggtatt ggacggagaa acagctgttc aggcacaaga acaagattca agcggaatgg
    13621 tgcgccagat cgttgccgac acacccggtg caatcagcta tgttgctttt tcttatgttt
    13681 ccgatgatgt agatacgttg aatgttaacg gtgtagaacc gacagatgaa aatgtgacaa
    13741 cgaacaaatg gacgatttgg gcatatgagc atatgtacac aagagatcat ccaaaaaaac
    13801 tgacaaaaga atttttagac tatatcttat ctgatgaagt acaagataac atcgttggag
    13861 aactaggtta tatccctgtt tctcatatga aagtcgaacg tgattggcaa ggaaatatcg
    13921 ttaaagagta atctttacac aaaatttaca aacttagcta aacttttaca tgttattaaa
    13981 accaaattga tgttcaattt gtacactgag tgagtatgtt aaacctgatt aagggggagt
    14041 catctgtgga agatgtgaaa aaagtattat taacaaaatc aaaacgttca aaaatggaac
    14101 agcgtggaaa attcatcagt tttttatgta tcgcgctgat cgtgttggtt gtattatcta
    14161 ttttttattt tgtagctagt aaaggattgg ccaccttttt tactgataag atcaatgtat
    14221 ttgattttct gtttggtaca gattggaatc caagccaaat cggagcaaat gggaaaccaa
    14281 tggtaggggc attgcctatg atcacaggtt cgtttattgt gaccttttta tctgctatcg
    14341 ttgccacgcc atttgccatt ggtgcagcag tattcatgac ggagatctct cctaaaaacg
    14401 gaacgaagat cttacagccg gtcatcgagc tgcttgtagg tattccttct gtcgtttatg
    14461 gttttatcgg tttatcagtt atcgtgcctt ttgtcagaag tatttttggc gggactgggt
    14521 ttggtatctt agctggtaca tttgtgttgt tcgttatgat cttgccgact gtcacaacga
    14581 tgactgttga tgcattaaag gcagtgccac ggcactatcg ggaagcttca ttagcgcttg
    14641 gtgccacaag atggcaaaca atctacaaag tcgtgctacg agcagccgtg cccgggattt
    14701 taacagcagt cgtttttggt atggctcgtg cgtttggtga agccttagct atccaaatgg
    14761 tcatcggtaa tgcagcattg atgccaacag gtcttactac tcctgcttct acattgacgt
    14821 ccatcttaac aatgggaatc ggaaatacaa tcatgggaac agttgaaaat aatgtgttat
    14881 ggtcattagc gctgatcttg ctattgatgt cattattctt taatatcgtg atccgtatga
    14941 ttgggaagaa aggagagctg aaataatgaa cgcaaaacgc tcagataaaa ttgctacagg
    15001 tgttttatat atagtttcgg ggatcatcgt attgatttta gcagctttac tactttatat
    15061 cttagttcgg ggaataccgc acatttcatg gtccttcttg accgaacctt ccaaagccta
    15121 ccaagaaggc ggtggaatcg ggatccagct atttaactcg atttatttgc ttttgatcac
    15181 gatgatcatc agttttccta tttctttagg tgcgggtatc tatctttcag aatatgctgg
    15241 aaaaaactgg ctaacagatg tgattcgcac gtcgattgaa atcttgagct cgttgccttc
    15301 tgtcgttgtc ggtttattcg gtttcttggt tttcgttatt caattccagt atggtttctc
    15361 gattatttct ggtgcattgg ctttgactgt attcaacttg cctcttttga ctagaacagt
    15421 tgaggagtct ttacaagcgg tccattacac acaacgagaa gcaggattgg ccttaggttt
    15481 gtcacgctgg gaaacagtga taaaagtggt ggttccagaa gcgacaccag ggattttgac
    15541 tggtgtgatc ctaagttctg gaagaatttt tggtgaagca gctgcattga tctatacggc
    15601 tggacaaagt gcacctgcgt tagattttac gaactggaat ccattaagtg tttcaagccc
    15661 gatcagcatt ttccgtcaag ctgaaacatt agctgtccat atttggaaga tcaatacaga
    15721 aggcacgatg cctgatggtg tttctgtttc ggctggcgct tctgccgtgt tgattattgc
    15781 tgttttactg ttcaacttcg gcgctcgtgc gattggcaaa cgattatacc gaaaaatgac
    15841 ttcagcctaa ggagaagaag caaaatgaaa aaatataact ggaatgaaac aaatgtcatc
    15901 accatgccaa aagagaaaga agtagcacta tatacggatg atctacatgt ctggtatggc
    15961 gacaatgaag caatcaaagg agtggatctg gaatttgaaa aaaataagat cactgcactg
    16021 attggtcctt ccggctgcgg aaaatctacg tatcttcgtt cgttgaatcg aatgaatgat
    16081 gggatcgcta atacgaaaat cactgggaaa atcatgtatc aaggcgtaga tattaatgcg
    16141 cctcaagtgg atgtttatga gatgcgcaaa cggattggca tggtttttca acgtcctaat
    16201 ccgttcagca agtcgattta tgacaatatt acatttgctt tgaaacagca cggcgaaaaa
    16261 aacaaaaaga aattagatga aatcgttgaa acaagcttga aacaagctgc cttgtgggac
    16321 caagtaaaag acagcttgga caaaagtgcc ttggctttat ctggcgggca acagcaacgt
    16381 ttatgtattg ctcgtgcgat cgcgatgaaa cctgatatct tgctgctaga cgagccggca
    16441 agtgctttgg accctatttc gacaggaacg gttgaagaaa cacttgtaaa cttgaaagaa
    16501 gactatacga tcatcatcgt gacgcataac atgcaacaag cagctcgtat cagcgactat
    16561 actgcctttt tctatttagg aaaagtaatg gaatatgaca aaactaacaa gatatttacc
    16621 agaccaaaaa ttcaggcaac cgaagattat gtgtccggtc attttggtta agacggaggc
    16681 ctcaacatga caaaagagat tatttcatct aaagatcttc atctgtatta tggaaagaaa
    16741 gaagcactaa aagggatcga tctaagcttc aatcaagggg aaatcactgc gatgatcggt
    16801 ccttctggtt gcggaaaatc cacttatctg cgttctttga accggatgaa tgacctgatt
    16861 ccgaatgtaa cgatcaccgg aagtgtttta tataaagaca aagacatcta tggtccaaaa
    16921 acagatgttg ttgaactaag aaaagaaatc ggcatggtat tccagcagcc aaacccattt
    16981 cctttttcta tctatgaaaa tgtcatctat ggattgaaat taaaagggga aaaagataaa
    17041 aaagtccttg atcaagtagt tgaagaaagc ctgaaggcag cgtctgtttg ggatgatgtg
    17101 aaagacaaat tgcataaaag tgctttatct ttatccggtg ggcagcagca gcgtgtatgt
    17161 atcgcacgtg ttttggcagt taatccggaa atcatcttat tggatgaacc aacaagtgcg
    17221 cttgatcctg tttctactgg gaaaatcgaa agtatgctgt tagaattaag agagcggtat
    17281 acgatgatca tcgtgaccca taatatgtct caagcttcac gtatttcaga taagacggca
    17341 ttctttttag atggtcactt gatcgaatac aatgatacga agaagatatt catgaatcca
    17401 gaaaaacaag agacagaaga ttatatttca ggtcgatttg gataaggagg aaacggaatg
    17461 ctacgtacac aatttgaaga agaattgctg aatctccata atcagttcta cgaaatgggg
    17521 atgatggtga gcagcgccgt gcacaagtca gttcgtgcat acatcaaaca cgataaaatc
    17581 ttagcccaag aagttatcga aaacgatata aatatcaata acatggaaac acgcttggag
    17641 aagaaaagtt ttgaaatgat cgcattgcaa cagccagtta caactgattt gcgtatgatc
    17701 attacggtca tgaaagctag ctcggattta gaacgtatgg ccgatcatgc ggtgtctgtt
    17761 gctaaatcca cgattcgcgt aaaagggcag acgagaatac cggaaatcga aaaagagatc
    17821 tccgatatgt ccgattatgt gaaaaaaatg gtggacaacg tcctagttgc ttatgtcaaa
    17881 acagacgaaa aagacgcacg tacgatcgcc aatatggatc aaagagtcaa tgactatttc
    17941 aatcgaatct ataatgcaac aatcaaaaat atgcaggaaa atcctgagac agtcatcagt
    18001 ggaacagact acttgaatgt tgccagttat ctagaacgga tcggagacta tgtgacaaac
    18061 atctgtgaat ggatcgtcta cttggctaca gggaaaatca ctgagttaaa tacgaaccac
    18121 aatgagattt tctaaactga agctgtgatt atgccgtttg tttaggaaaa gaggttgtga
    18181 aatcagcggt tgtgaaaaag ctgttctgca tcaagtaata agaacagtca aacaaaaaat
    18241 agctcctcat atttttcgtt tggctggact tattaccgca gatgcaagct tttgaacacc
    18301 gtttattcgg gaaagggttt gtgacaaaac atgtcacaaa cccttttcat catttcatag
    18361 aaaggataaa gaatgcaaaa aaaaattagc atcatcacta tattttttat ttgtgtgctt
    18421 acttcatggg ttattcagca tcaagccgct ttatatgaag tacctgtcat cgagatagaa
    18481 aaagtacgaa taaaagagga tcatcaattg attacaggaa aactgatgaa cacggatcaa
    18541 aaaggagaat cgatttattt atcggttcct tatcaaaaaa atcaaataga aacagcaaat
    18601 ataaaagcga gacaaatgta tctagtccaa atgcatggag atgaatggca gctagtagca
    18661 aaaaaaaatg atggctggct tttcttcttc acaagtatct tcattggcgc catgttgctt
    18721 attggtggaa aacagggtct atttgcttta ggaagtctca tcatcaatat cgttttactt
    18781 ttacttttgt tgctcatctt tactaaaaca gaagggattt ctctattaaa tatatctatc
    18841 ctgttcgtcg ttatagggat gattattagc atattggctt tagatggatg gaatagaagc
    18901 agtataatca aaatttcagc tgcagttacg agtgtttttt tagcattttt tatttgtctt
    18961 ttgacaatga atcattggaa agaccaagga ctgcgctatg aggaactgaa ttatctgaca
    19021 cgaccgtatc gttctgtttt tctttctagc gtactgattg gaacagctgg aggaacactc
    19081 gataccgtta tcacagtcat tgcgacatta gaagaattga ctaagcgaca accagaaata
    19141 acagcgaaac agttatggct ttcaggaagg caagtgggtc gagatgtgat tggctcgatg
    19201 accaatatcc ttttgttcgt ctatatcagt gggtcagttc catcgcttct tttatattta
    19261 ggaaatcaat ggtcgttcaa agaaacgata gaacagcatt tatcattgga atttttacgc
    19321 gtcattgctg gcagcttagg aatagtatta tcgatcccta tctcggtcct cttttttctg
    19381 actgtaagga ggctgaaacg atgaatgtac ttattatact tgttgggatt ttagcaatca
    19441 gcgtgctact tattggcggt acgcaaggta tgtatattct tttaggctta ttcatcaatt
    19501 tagggatctt tttcctgttg ttattcggtt atcatcagaa gtggccgata ctggcattgt
    19561 cggtcatagg atttttattg attgctgtgg ttatcttatt ttttatcaac ggttataatc
    19621 taaaaatgcg tgcagctttt gtgagtatac tgatcttttt attttgtttc ctactattgc
    19681 ttcctatcac tgatttttta gcaatccaag gttttacatc ggtagaacta gaagaattat
    19741 ctggcttaga taagacttta gcgattgatt ttagattact tacgagatcg ttgcttctga
    19801 ttagtcttag tggtgctgtt ttagatgcga gtgtagcaat ttctagtggg acattcgaag
    19861 tatatcaggc aaatccgcaa ttatcttttt accaattgcg ccattctagt ttcgctattg
    19921 ctaaaaaaat attggcgtca acagtaatga cacttctttt tgcattcatg ggaagttctt
    19981 tagcgttgat cctctggttt attgatttag acattccttt tcagcaagtg atcaatgaaa
    20041 aatcatttgt tctagaatat acgatggcta ttcttaccac attgtccgca ctacttgttc
    20101 ttcctttaac ctgcgtgact acagcatatc tctttacaaa aaagaaagaa caactcaaga
    20161 tggagtaaaa gttacaactt aagtcctatg acatttttac tgaatcagtg cataatatgg
    20221 atgtaaggaa aagcttgcaa acaattttgc ttaaggaggc aatttccatg aaagaaagag
    20281 aacgtatttt agatttagtg aaaaaaggaa tcctttcgac tgaagaaggc ttagatttat
    20341 tagaaagcat ggcaactgaa aaagacgaaa agcaaatcaa aaaagaagca gacaaggtaa
    20401 ctgctagtca taaagaaaaa gatcaggcaa gtcaattgat cgataaactt gaaaacggcg
    20461 aagaagaaat ttctgagcca gttgatccaa aggaaagaga aagacaagat caagaaaact
    20521 tagaaaagat cttagatgaa ctagcaactg aagcgaataa aacttcggcg cgtctagatg
    20581 aagtaaatgc tcaattcgct gacaataagg cagcacgcaa tgagaaacag gaagcattga
    20641 tgcagctgaa tacaaaagaa gaattaggcg agttgacaga agaagaatta gcacagcgtc
    20701 agacgttaga agcagaaatc aaagaattag aagctagtgg cgatacactg ttagaagaac
    20761 aattgaaatt agaagcagaa ttaaaagata tccgtaagaa tcaatggtct gagaaaaaag
    20821 aaacgtttac tgataagttt gaattgccag atgattggaa agatcaagca acagatacac
    20881 tgaatcaagt aggcgaaaaa atgtcagaag ctggatcaca gttaggcaaa ttcttgaaga
    20941 aaacattcca aactgtttca gaaacagtga atgacaacat ggaatggaaa gatgtcagct
    21001 tacgtgtccc tgggattgcg acaacgaaat ttgagcatga attttactat gaagctcctg
    21061 cagcaagtat ccttgatatc aaggcagcaa acggaaacgt gacgttaaaa acgtgggaca
    21121 gcaacgatgt gaaagttgaa gctaagatca aactttacgg aaaaatgggt gctgaaccat
    21181 ttgaagcatt ctctgaacgg agccagattg aggttaatga agatcatatc tccttccaaa
    21241 ttccaaataa acgtgtgcgt gcagaccttg ttttctactt acctaaacga gtatacgacc
    21301 acgcagctat taaacttcta aatggcaaca tcatgattga aacattggaa gctaaagata
    21361 tttatacaaa atctacgaat ggtaacatca tcgtggacca attaactgca acgatgctgg
    21421 aagtagaagg tgtaaacggc aatatcgata ttcgaaacgg gaacatctta gattctatta
    21481 tcgaaacagt aaatggtaca gtgacatttg gtgcgacagc agaaaacctt tctgtgtctt
    21541 tggtaaatgg tgatgtacgt cttacgatta aagaagataa tttgaaaaaa gtagaagcaa
    21601 gttcagtgaa cggaaatgtc aaagtcgctt taccagatgg catcggtttg gaaggacatg
    21661 ctaaaacaag tcttggaagt atcaacagcc gtctgtccaa ttacgaagta gttcgtgaga
    21721 aaaaagaacg gacaaaccaa atgttgcaat tccgtcgtgt ttcagatggt gaaatcgcgc
    21781 aagtgcaact ttcaacgaca acaggaagta tctatttaaa agatacagat aaataaagag
    21841 gttgtgaaag agatgttcag ccttgagcaa taagaagcga ttttgtaaaa tagcttcccc
    21901 tattttacaa aattgtgcct tattgccgat agtctatctc ttgaacaccg tttaccaaga
    21961 gattatgaac ctgccaatta tcgccgagtc acaaggaata atttcagaaa aagctcgtca
    22021 cgttttatga atatggtaat ttgtgaccga gaattttgca gaaagacacc gattaagaag
    22081 aaggttgtca caacgatttt cttcatttaa aatagtagaa cagaggtgag acatgatgaa
    22141 aaaaaagttg acaaaatcta ataaaaatgt tgttttgaca gggactttag caggaatagg
    22201 agaatacatc gggattgatc cgactgttat ccgtgtgctt tatgtattcc tgagcttagt
    22261 tgcttttgga agtccaatta ttttatacat tttattagct ttgattatcc catctgcgcg
    22321 ttctgcacga acaaactatg gacataacaa tgcatattat gaaaaaaaca attatcgtga
    22381 acaaactcgt gaacaaacaa aaaaacgcaa agaagcggaa aaaatcgatg atgacgaatg
    22441 gagtgacttt taatgtcgta ctttcaacgt attttagtta atacgttaac attcatatca
    22501 ttggctgttc tttttcctgc gatggtccat gtgagcagta tttggacggc cgttcttgcc
    22561 agcttcgtat tgtctgtgtt gaatatgttt gtcaaaccga ttttgacgat actgtccctg
    22621 ccctttacat tagtcacatt gggattgttt acgtttgtta tcaatgcagc gattcttaaa
    22681 atgacctcct tttttgtggg agcagaacat tttagttttt cttcattcgg tgcagcgttg
    22741 ttagtagcta tcttgatgtc gcttgtcaat gtaattgtca gcgaacataa cagtagaaaa
    22801 taaaagaaag ctgtgccgaa ctatcggcgc agttttttta tttagaatca ggaatgcgtt
    22861 ttctattaca ttggtaatta aataaaaacg ttttttttaa
//
LOCUS       DAXQKX010000044        22865 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.044, whole genome shotgun sequence.
ACCESSION   DAXQKX010000044 DAXQKX010000000
VERSION     DAXQKX010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22865
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.044"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..197
                     /locus_tag="ACF3MF_001862"
     CDS             <1..197
                     /locus_tag="ACF3MF_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927848.1"
                     /translation="WFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFLVIALIAVGLV
                     FNASGVKDVLLNLFNRIVGA"
     gene            210..713
                     /locus_tag="ACF3MF_001863"
     CDS             210..713
                     /locus_tag="ACF3MF_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HFE3927849.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKEQIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCNLAEELEGTPIGEAASEIQHAFFNSFEEMVEH
                     VDDIVYYPDCDDMSDVAHYLIVEAGDFGEVPEQLKPYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPE"
     gene            839..1876
                     /locus_tag="ACF3MF_001864"
     CDS             839..1876
                     /locus_tag="ACF3MF_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic GMP-AMP synthase DncV-like
                     nucleotidyltransferase"
                     /protein_id="HFE3927850.1"
                     /translation="MANIQTSFIDFHNSIRLDVEDNTLLKDYKDQVIDGLKDYLPDDV
                     KFETFLQGSYSVYTGIKSCDEKIDFDIDIAVAFEIDHTVYEDPREPKLWVKEALVEIF
                     PNAQVNLKVPCVTATFTGKKTKKNVHVDVAVYAKEDENYFLAKAKEFSAPENRCWEEA
                     DPKVLKEKINSHVADSDDRKQFRRCIRYLKRWKDNNFNQEYKPTGIGLTINVMDTFLV
                     NKSTDFLTRKVQYNDMECMKQIVSSLKDSFVYEYSETDGWHYRLHAYLPVKPNSDTYS
                     KMTVNQMSDFKNKLSKLYDDLIFAIDTEDEYEATKRLNNQFGEDFLIISEEEVTEKNL
                     RNAFVTDYPSA"
     gene            1891..3588
                     /locus_tag="ACF3MF_001865"
     CDS             1891..3588
                     /locus_tag="ACF3MF_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="E2/UBC family protein"
                     /protein_id="HFE3927851.1"
                     /translation="MDYTDILKEKLTDVVRLFDGNYYGDFSFATIGKLRLKIEIPKHF
                     PLVLPRIYIHNFDHLGLYLPHVEKDGLVCFSSDINYLVDEENSELVLLQCVNKTIKTI
                     EEGLKGLNKNDFRKEFVAFWDKQENQISLFYLCEPALFIKSVDTIMYGKSLVALDKEN
                     ELQLNAASRLFNGEKEDTHELDAYYVPIRNKNNIMPPKNNKAWSKKDILQIVKKNVTG
                     ANKRFFLKLEKRKNRHNVLLILDIPIEEKSNNVIIGFLFTKQSGSIKDYKGTPRTVLV
                     QRHDELYLVNRTSGENYGLGANIAIVGVGSVGSKIAENLGPLGVRKMTLIDNDCFQAE
                     NLYRNSLGADSLKNARSQNNFFKVDLMQEELEKKFPYLCVEVESMNVLDLISMQPGFF
                     KEYDYVFVCIGDTMASLALNNYFSKSSQKVFYSWLEPYGIGGHTLFINYSLNQKGCFN
                     CLYTDSNSKNRCSNRASLVKEGQIFERTLASCRSKFIPYNAIASTECAINAIKLFHKV
                     NQNNMTNSTLFSWIGDGSTFENLGYQYSDRNTFLNGVNKFEERFFSKYCKVCGELDD"
     gene            3581..4042
                     /locus_tag="ACF3MF_001866"
     CDS             3581..4042
                     /locus_tag="ACF3MF_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mov34/MPN/PAD-1 family protein"
                     /protein_id="HFE3927852.1"
                     /translation="MIKFSCDRIVIEVRDEVLKIFEQYRQGKDDLPEAGGVLHGKRLK
                     NGSIIITDITTPQIGDIQKRLLFKKNREIHQQLSNEKWIESNKFSIALGEWHTHPEAV
                     PTPSNVDKKSWRLNVSKQHDDRVYVFIIVGFSDLRMWLLSKKSDIRQAIKL"
     gene            4055..4915
                     /locus_tag="ACF3MF_001867"
     CDS             4055..4915
                     /locus_tag="ACF3MF_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927853.1"
                     /translation="MKSQKNIWWWGFLVGKVMIPALLLISLPMITFFFTNKKMSKEAV
                     IFFFGDQKATFIETLVTSLQLNLNYIFSIIIVISLLNFFKKRNSGKVFNSNGNVYYNY
                     FYFVFWVAATLLGYDKIQIAGIPIHMQYKLVLSGIFSEVLPDIYDDHYDSDGTCKVSI
                     EKENFDDIDGYDSVNLLIIDTYDIKMSELSMENQTYPTIIVRGNSIDGVRKVNRSLIL
                     EIKKTMDEIQKSDFKKVFVASTSNPKNSINIINSSFRFFGRSRRFKLYVLQKDYASNG
                     KYSKKYRIFI"
     gene            4953..5342
                     /locus_tag="ACF3MF_001868"
     CDS             4953..5342
                     /locus_tag="ACF3MF_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFE3927854.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLMFV
                     IVFAHVPPLSMIEGAFLKYLGIPIAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            5329..7776
                     /locus_tag="ACF3MF_001869"
     CDS             5329..7776
                     /locus_tag="ACF3MF_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFE3927855.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDLQTDALVSMI
                     GDSQIDYRFFIGFKLISTDEEVNLKNLRKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVKRVTPSDLTYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPTRCLIEEKPRYLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAKSVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HKEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALASAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVIVELRKEDSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDKEDESNQKCMRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            7781..9889
                     /locus_tag="ACF3MF_001870"
     CDS             7781..9889
                     /locus_tag="ACF3MF_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HFE3927856.1"
                     /translation="MKKKLFRIFGIVLISLVTLIILLSLVGTVAEATGLVDDTVGAGN
                     LYSQYSLGNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEVGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMNMFNLQSNDSQSMGRRVMRKPQMLMNRTLR
                     QLNRNVGRTLAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEIPSDLNKEK
                     PIPNNKKQSRMNLAGRKVGKVLDTQALVKDKTKQVKDGVRNTPTNLKYNFHKGIEKTK
                     KAPEEFKRGLVQEKANRGELREKQQQRRDEKIAEKRKVLNEIGNPHGKRRENVPIKAK
                     VQSQKDRAPKRIVRANSNPEIKRKFASQEIISKGINQSSSKKNSFQQVKRRSTLSKRT
                     NRKVQKSLNPHPKPRSGEKK"
     gene            9886..10818
                     /locus_tag="ACF3MF_001871"
                     /pseudo
     CDS             9886..10818
                     /locus_tag="ACF3MF_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
     gene            11550..13378
                     /gene="ltrA"
                     /locus_tag="ACF3MF_001872"
                     /pseudo
     CDS             11550..13378
                     /gene="ltrA"
                     /locus_tag="ACF3MF_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347183.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            13555..14466
                     /locus_tag="ACF3MF_001873"
     CDS             13555..14466
                     /locus_tag="ACF3MF_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFE3927857.1"
                     /translation="MKIKIERNQKEKSLKKKKERVVSVGKHRKMVLALWLLLSCSLTF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGIENFTKDFSKEYFSWKNNKEAIEKRMNNL
                     EQYLTEEGFALSQDMVRADIPTNSEVQSVKVLDVEKSSEEFVVSFLVEQKITEGKKAQ
                     SISSAYRVTIFEDENRNYIVTSLPTMIAKPDRAKYKTKQVENDSKIDAKTTEEIAEFL
                     ETFFKLYPSASEKELEYYVENDAMRPINIDLKFSKLEDPVYLQNGKKILVSTKIKYLD
                     NVSKTTSYFQYKLILQKNGNWKIIDVK"
     gene            14653..14940
                     /locus_tag="ACF3MF_001874"
                     /pseudo
     CDS             14653..14940
                     /locus_tag="ACF3MF_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(15128..15343)
                     /locus_tag="ACF3MF_001875"
     CDS             complement(15128..15343)
                     /locus_tag="ACF3MF_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927858.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(15602..15811)
                     /locus_tag="ACF3MF_001876"
                     /pseudo
     CDS             complement(15602..15811)
                     /locus_tag="ACF3MF_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
     gene            complement(16114..17553)
                     /locus_tag="ACF3MF_001877"
                     /pseudo
     CDS             complement(16114..17553)
                     /locus_tag="ACF3MF_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(18101..18772)
                     /locus_tag="ACF3MF_001878"
     CDS             complement(18101..18772)
                     /locus_tag="ACF3MF_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HFE3927859.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRYLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCQCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEKWIAYITLK
                     KRGTI"
     gene            complement(19121..20572)
                     /locus_tag="ACF3MF_001879"
     CDS             complement(19121..20572)
                     /locus_tag="ACF3MF_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFE3927860.1"
                     /translation="MKKSLKLASAVILMSQLFIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTLSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSAESSTTSSSTSEITSSKVTRPNHIESSKKEAPKTEGQTKNFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            complement(20684..22027)
                     /locus_tag="ACF3MF_001880"
     CDS             complement(20684..22027)
                     /locus_tag="ACF3MF_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFE3927861.1"
                     /translation="MKKIVIIGSNHSGLAAARFLNLCDSNYEVILIDKKSEISYLECG
                     TSLFIKREVSNLEDLFYQNRRELNSKIKKLFLETAVDKIDIQNKKIICVKKDGTRFSQ
                     EYDKLILATGSKQIMLDVPGNNLANIFSIKNFPNAKEIFKALDDNTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGKKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHIDNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPVFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
     gene            complement(22161..>22865)
                     /locus_tag="ACF3MF_001881"
     CDS             complement(22161..>22865)
                     /locus_tag="ACF3MF_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rib/alpha-like domain-containing protein"
                     /protein_id="HFE3927862.1"
                     /translation="DADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKV
                     DVSTAGNKKGIVVVTYPDGSKEEVEVTISVEDKKAPNKPQVDPITEGDQIVTGKTEPN
                     AEVTVTLPNGSQYHGTADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSN
                     EKDSEKAVSKDNKTDNQGSKQNKNRGKSSPQKQSSKAYPKTGEIDSNIFTISGGLILL
                     GTLGLLGYKNRKKENE"
BASE COUNT         7500 a         3866 c         4298 g         7201 t
ORIGIN      
        1 aatggttttt aaccaatgct caatctttag tcttactagc gattgtggtc attggtttgt
       61 ttttaggatt taaacgggag ttttccaaac tgattggctt cttggtgatt gctttgattg
      121 cggtaggtct ggtctttaat gcttctggtg tgaaggatgt cctactcaat ttgtttaacc
      181 gaattgtcgg tgcctgaggg ggaatcacaa tggaacagat gcgtgtttat attgcgaacc
      241 ttggaaaata caatgaaggt gagttggtgg gggcatggtt taccccacct gtcgattttg
      301 atgaagtgaa agaacagatt ggattaaatg acgaatatga agagtacgcg attcatgatt
      361 atgaactgcc ttttgagatt gatgagtata cgccaattga agagattaat cggttgtgta
      421 acttagcgga ggaactagaa ggaacgccaa ttggtgaagc tgcttctgag attcaacacg
      481 ctttcttcaa ttctttcgag gaaatggtag agcatgtgga tgatattgtc tattatccag
      541 attgcgatga tatgagtgat gtggcgcatt acttgattgt agaagctggt gattttggcg
      601 aagttccaga acaattgaag ccgtatattg attttgatgc ttgcggtcga gatttggaga
      661 ttggaggaaa ttatttggtt actagtcgtg gagtttttga gtatccagaa tgaatcaaca
      721 ctatatatag tgtttgatta gtatatgtaa gcaaaaaaac acaatatata gagtgcaaac
      781 tgaagggtaa tgtgatataa tatttgccga agaaatattt ttgaaatgag gtaatattat
      841 ggcaaatatt caaacaagtt ttattgattt ccataattca attagattgg acgtagaaga
      901 caatacgcta cttaaggact ataaagacca agtaattgat ggattaaaag attacttacc
      961 tgatgatgtg aagtttgaaa cttttttaca gggaagctat tctgtttata ccggaataaa
     1021 aagctgtgat gaaaaaattg attttgacat cgatattgca gttgctttcg aaattgatca
     1081 tactgtttat gaagatccaa gggagcctaa actgtgggta aaagaggcgc tagttgaaat
     1141 ttttcctaat gctcaagtta atttaaaagt accttgtgta actgctacat ttactggaaa
     1201 aaagacaaaa aaaaatgtgc acgttgatgt tgcggtttat gctaaagaag atgaaaatta
     1261 tttcttagca aaagcaaaag aattcagtgc tcccgaaaac cgatgctggg aggaagcgga
     1321 tcccaaagta ttaaaagaga aaattaatag tcatgtagca gattcagatg atcgaaaaca
     1381 atttcgaaga tgtattcgct atttaaaaag atggaaagat aacaatttta accaagaata
     1441 taaaccaaca ggaattggac ttacaattaa tgtgatggat acgttcctag ttaataagtc
     1501 cactgatttt ttaactagaa aagttcagta taatgatatg gaatgtatga agcagattgt
     1561 ttcttcgctg aaagattcat ttgtgtatga gtacagtgaa acagatggtt ggcattatcg
     1621 tctacatgca tatcttccag tgaagcctaa cagtgacacc tattcaaaaa tgacagtgaa
     1681 tcagatgagt gattttaaaa acaaactttc taaattatat gatgatttga ttttcgctat
     1741 cgatactgaa gatgagtatg aagctacaaa acgattaaat aatcaatttg gggaggattt
     1801 tttaattatt tcagaagaag aagttacaga aaaaaactta agaaatgcat ttgttacaga
     1861 ctatccgagt gcttaggttg gtgttaaaga ttggattata ctgatatttt aaaagaaaag
     1921 ctaacagatg ttgtgcgttt attcgatggt aattactatg gggatttttc atttgctaca
     1981 attggaaagt tgcgtttaaa aattgaaata ccaaaacatt ttccattggt acttcctagg
     2041 atttacattc ataattttga tcatttagga ctttacctac cacatgtaga aaaagatggg
     2101 ttggtatgtt tttcttcaga tataaattat ttagtagatg aagaaaattc agaattggtt
     2161 ttattgcagt gtgttaataa aactataaaa acaattgagg aaggtttgaa agggttaaat
     2221 aaaaatgatt ttcgaaaaga gtttgttgct ttttgggaca aacaagagaa tcaaatttcg
     2281 ttattctacc tttgtgaacc agcgttgttt atcaagtcag ttgatacaat aatgtacggt
     2341 aagtctttgg ttgctttgga taaagagaac gaattacaat taaatgcagc gagtagattg
     2401 tttaatggag agaaagaaga tactcatgaa ttagatgcat actatgttcc aattagaaac
     2461 aagaataata ttatgccccc gaagaataat aaagcatggt caaagaagga tattttacaa
     2521 atagtaaaaa aaaatgtaac aggtgcaaat aaaagatttt ttttaaaact tgaaaaaaga
     2581 aagaatagac ataatgtttt acttattcta gatatcccaa ttgaagaaaa gtcaaataat
     2641 gtcataattg gatttctttt tacaaaacaa tctggatcta taaaagatta taagggtacg
     2701 cctaggactg tattagttca gcgtcatgat gaattatatt tggtgaatag aacgagcgga
     2761 gaaaactatg gattgggtgc taatatagct attgttgggg tagggtcagt tggcagtaaa
     2821 attgctgaaa atcttggtcc attaggtgtg agaaagatga cactcataga caatgattgt
     2881 tttcaagctg aaaatttgta tcgaaattca cttggtgcag atagtttaaa aaatgcccga
     2941 tctcagaata atttttttaa agttgattta atgcaggagg agctcgaaaa aaaattccca
     3001 tacctttgtg ttgaagtgga gtcaatgaac gttttagact taattagtat gcaacctggt
     3061 tttttcaagg aatatgacta tgtttttgtt tgcataggag atacaatggc aagcctggct
     3121 ttaaataatt atttttccaa aagtagtcaa aaagttttct attcttggct ggagccatat
     3181 ggcattgggg gacacactct atttataaat tattctctaa atcaaaaagg ttgtttcaat
     3241 tgtctttata cagattcaaa ctctaaaaat aggtgttcaa atagagcttc tctggtaaaa
     3301 gaaggacaaa tttttgaaag gactttagcg agttgccgct caaaatttat accatataat
     3361 gctattgcct cgacggaatg tgcaattaat gcaataaaac ttttccataa agtcaatcaa
     3421 aataatatga ccaatagtac tcttttttca tggataggag atgggagtac ttttgagaat
     3481 ttaggatatc aatatagcga cagaaatact tttcttaatg gagtcaataa gtttgaagaa
     3541 agattctttt ctaaatattg caaagtatgt ggggagttag atgattaaat tttcgtgtga
     3601 ccgtattgtc attgaagtaa gggatgaagt tcttaagata tttgaacaat atcggcaggg
     3661 aaaggatgac ttgcctgaag ctggaggagt tcttcatgga aaaagactta agaatgggag
     3721 cataataatt accgatataa caacacctca aataggagat atacaaaaaa gattactctt
     3781 taaaaaaaac cgagaaattc atcaacagct ttctaatgag aaatggatag aatcaaataa
     3841 gttttctatt gcattgggag aatggcatac tcatcctgaa gctgtaccaa ctccatcaaa
     3901 tgttgataag aaaagctgga gactgaacgt gagcaagcaa catgatgata gagtttatgt
     3961 ttttattatc gttggatttt ctgatttgag aatgtggtta ctgtcaaaaa aatcagatat
     4021 taggcaggct ataaaactat aaaggagtga ttaggtgaaa tcacaaaaga atatttggtg
     4081 gtgggggttt ttagtaggaa aggtaatgat accagccctt ctcttaattt ctctaccgat
     4141 gattactttt ttctttacca ataaaaaaat gagtaaagaa gccgtgattt ttttctttgg
     4201 agaccaaaaa gctaccttta ttgaaacgtt agtaacatct cttcagctta atttgaatta
     4261 cattttttca attattattg ttatatcgtt attgaatttt tttaaaaaaa gaaattcagg
     4321 aaaggtgttt aactctaatg gaaatgtgta ctacaactat ttttattttg tattttgggt
     4381 agcagcaact ttacttggtt atgataaaat tcagattgca ggaattccta tacacatgca
     4441 atataagttg gttttgagtg gaattttttc tgaggtgttg ccagatatat acgatgatca
     4501 ttacgacagt gatggaacat gtaaagtaag cattgaaaaa gaaaatttcg atgacatcga
     4561 tggatatgac tctgtgaact tactgattat tgatacttac gatataaaaa tgagtgaatt
     4621 atctatggaa aatcaaacat atcctacgat aattgttaga gggaattcaa tagatggagt
     4681 tcgtaaagtt aatagatctt taatcttgga aataaaaaaa acaatggatg aaattcaaaa
     4741 aagtgacttt aaaaaagtat ttgttgcttc aacatctaat ccaaaaaata gtatcaatat
     4801 tattaattca tcgtttagat ttttcggtcg atcacgtagg tttaaacttt atgttcttca
     4861 aaaggattat gcaagcaatg gaaagtatag taagaaatat agaattttta tttaagaagg
     4921 aatttttcct tctttttatt ttggaggaaa ctatgaaaaa aataaaaagc tacaccagta
     4981 tttgggcagt tgaaaaagtc atttatgcga ttaatgactt tcagctgcct tttcctgtga
     5041 cctttaacca gatggcttgg tttgttttat ccttgatgtt tgtcattgta tttgcccatg
     5101 tgcctccgct atccatgata gagggggctt ttttaaaata cttgggcatt ccgatagcgg
     5161 tcacttggtt catgtcgcaa aagacctttg acggtaagaa accattggga tttttacgat
     5221 cctttatcag ctatcactta cggtttaagg tcacttttgc aggaaagaaa gttaaagaac
     5281 agaagaaacg atgggacgaa ccaatcacct tggtaaggag tgtgaattat gtacccgatt
     5341 aagtatattg aaaataatct tgtctttaac caagaaggcg agtgttttgc ttactatgaa
     5401 ttagtgcctt acaattactc ctttttgtca cctgaacaga agtatcaagt acatgataac
     5461 tttcgccaat taattgcgca aaatcgtgaa ggtaagatcc atgccttaca aattgccaca
     5521 gaaagtagta ttcgtgccac acaagaacgt tcgaaaaagg aaattaccgg tagactcaaa
     5581 gaagtagcaa agcaacgaat tgatttacag acagatgcat tagtatccat gattggcgat
     5641 agtcagattg attatcgctt ctttattggc tttaaactga tttcgacaga tgaagaggtc
     5701 aatctaaaga atctcaggaa atctttcttt tctggacttc aagaatttgt ctatggagtg
     5761 aatcatcatt tgatgggtga ttttgtttcc ttatccaatg aagaaattcg tcgctatacc
     5821 aagcttgaaa aactaatgga aagtaaattg gctcgaagat ttaaagtcaa acgagtaacg
     5881 ccgagtgact tgacgtattt aattgaacat atctatggtg aaaaaggcac accgtttgaa
     5941 gaatatgaat tccagctacc aaagaaaaag ctgaaatcag aaacgctggt gaaacgttac
     6001 gacttattac gtcccactcg ttgtttgatt gaagaaaagc ctcggtactt acggatggaa
     6061 catgaaaatc atgagtctta tgtagcgtac ttaacaatta ataccattgt aggggaaatg
     6121 gagtttcctt cctcggaact tttctattac cagcaacaac aatttacgtt tccgattgat
     6181 acttcaatga atgtggaaat tgtgacgaat aaaaaggccc tagctaccgt tcgtaataag
     6241 aaaaaggaat taaaagattt agacaaccat gcctatcaat ctgataatga aacgaactcc
     6301 aatgtattag atgctttgga ttccgtggat gaattggaaa ccaccttgga tcagtcgaaa
     6361 gaatccatgt ataaactaag ctatgtggtt cgagtgagtg ctaaatcagt ggatgaatta
     6421 aaacgccgct gtgatgaagt gctcgatttt tatgacgata ccaatgtaaa actagtccgg
     6481 ccctttggcg atatgatggg tctacacaaa gaattcttac cctcaagtaa gcgatacatg
     6541 aatgactata ttcaatatgt tacgtctgac tttttggcgg gacttggttt tggggctact
     6601 caaatgctag gagaattaga aggcatttac tttggctata acgtagatac ggggcgcaat
     6661 gtttacctga aaccggcatt ggcatcacaa ggggtcaaag gctcagtaac caatgctttg
     6721 gcatctgctt tccttggttc gttaggtggg gggaaatctt ttagcaacaa tctcttagtc
     6781 tattatgccg tcctttttgg tgggcaagct gtgattgtcg atccaaaagg agaaagaggc
     6841 ggttggaaag aaacgttgcc agaaattgcg gatgaaatta atattcttaa cttgaccagt
     6901 aagccagaaa atcaaggctt acttgatccc tatgtgatta tgaagaaaaa gaaagactca
     6961 gaaagtttgg cgattgatat cctgaccttt ttaacaggga tttccagtcg ggatggggag
     7021 aagttccctg tgttacgcaa agccattcga acggttaccc aaagtgatca gcgaggatta
     7081 ttacaagtaa tcgttgaatt gcgtaaagag gactcaccag tcgcggaaaa tatcgcggat
     7141 cacatcgagt cctttaccga ttatgatttt gcccatttgc ttttctcaga tggttcgatt
     7201 acccagtcga ttagtttaga taagcagtta aatatcattc aagtagcgga tttggtttta
     7261 ccagatgcag aaaccacttt tgaagaatat accaccatgg aattgctgag tgtttccatg
     7321 ctaattgtta tttccacttt tgccttggac tttatccata gcaaccgaga aattttcaag
     7381 attgtggacc tggatgaggc ttggagtttt cttcaagtag ctcaaggaaa aacgttatcg
     7441 aataaattag tgcgtgctgg tcgggccatg aatgccggtg tttacttcgt cacgcaaaac
     7501 agtgatgact tgttggatga acgtttgaag aataatattg ggctaaagtt tgcatttcgc
     7561 agtaccgata ttcatgaaat caagaaaacc ttggaattct ttggattaga taaagaagat
     7621 gaaagtaatc aaaaatgcat gcgagatttg gaaaatgggc aatgcttgat gcaggatttg
     7681 tatggtcgag taggtgtggt ccaagttcat ccagtctttg aagaactttt ccatgctttt
     7741 gatacccgtc cgccagttca agagagaatg gagtgaggag atgaaaaaga aactttttcg
     7801 tatctttgga attgttttaa tcagtttggt cactctgata atacttttga gcttagttgg
     7861 aacggtagct gaggcaacag gtctggttga tgatacagtt ggagccggaa atctttattc
     7921 ccaatattca cttggtaact atcagttgga tttctttgtg gatagttcgt gggattggct
     7981 gccttggaat tggggtgatg gcctagggaa gagcgtaatg tatggacttt atgccattac
     8041 taattttatt tggacagtta gtctctactt atcaaatgcc acgggctacg tggttcaaga
     8101 agcctataag ctggatttca tttcagatac ggctgaaagt attgggaaga atatccaaac
     8161 cttagccggc attaccgaaa atggactcca gacctcgggc ttttactttg ggtttctatt
     8221 attgatgatt ttagctctag gagtttatgt ggcgtataca ggattattaa aacgagaaac
     8281 taccaaagca gtccgggctg tcattaattt tgtgatgatt tttctacttt cgggttcgtt
     8341 cattgcgtat gcgcccacct atatcacaaa aatcaatgat tttagctcag atgtcagcga
     8401 agcggctctt agccttggaa ccgagattgt cgtgccgaat tcagaaagcc aaggaaagga
     8461 cagtgtggat ttaatccgag atagcttgtt ttccattcaa gtccaacaac cgtggttact
     8521 cttgcaattt gatgattcca atatagaaga agttggcgaa gatcgtgtta acaaaatcct
     8581 gtctgtaagt ccagatgaaa ataaaggcaa ggatcgggaa gaagcggtca aagcggagat
     8641 tgaagataat gacaatgcga atctcagtat taccaagacc atgaaccgct tagggaccgt
     8701 ggtctttttg gtgttgttca atattggcat atccttcttt gtctttctcc taacagggat
     8761 tatgttgttc tcgcaaattc tctttattat ctttgcgatg tttttgccga ttagtttctt
     8821 attgtccatg ttgccgactt atgagagttt gggcaagaag gcgattattc gcttgttcaa
     8881 tacgattatg atgcgagcag gagttacttt ggtgattacg actgcattta gcatctccac
     8941 gatgtttttc aatatttcgg caacctatcc atttttcatg gttgcttttc tgcaaattgt
     9001 gacctttgcc ggtatctatt tcaaattggg cgacattatg aatatgttca atctccagag
     9061 taatgatagc caatcaatgg gaagacgggt catgcgaaaa ccgcaaatgt taatgaatcg
     9121 aacattgcgg caactcaatc gaaatgtggg acggactttg gcttttggtg gtggtgcagc
     9181 agttggaaat aagttggcaa aggaacaatc aaaatccaaa tttaagccat ccggttcttc
     9241 tctacgaaag aattcacgat taccgaacga tcacgagata ccatctgact tgaataagga
     9301 aaagccaatt ccaaataata agaaacaatc ccgaatgaat ttggccggga gaaaagtcgg
     9361 caaggttctg gatacccaag ctttggtgaa agataagacc aaacaagtaa aggatggagt
     9421 acggaatacg ccaaccaact tgaaatacaa cttccataaa ggaattgaaa aaacgaaaaa
     9481 agcaccggaa gagtttaagc gaggactggt ccaagaaaaa gcaaatcgag gagagttgcg
     9541 agaaaaacaa caacaacgta gagacgaaaa aatagctgaa aagcgcaaag tattgaacga
     9601 aatagggaat cctcatggga aaagaaggga aaatgttccg ataaaagcaa aggtccaatc
     9661 tcaaaaggat agagcaccaa agcggattgt gagagcaaat tcgaatcccg aaatcaaacg
     9721 aaaattcgct agccaagaaa tcatttcaaa aggaataaac caatcctcaa gtaagaaaaa
     9781 ttcttttcaa caagtgaaac ggcggtctac tctgtccaaa cgaaccaatc gaaaagtaca
     9841 aaaaagtttg aaccctcatc ccaaaccaag gtcaggtgag aaaaaatgaa cgtaaagaaa
     9901 ttaagtgcca tttcgttaac tttcctaaca atctctttta tgggtatctt gatgtgtgtg
     9961 ggcttattgt ttggtgaaga cagtgaagga agtagtagtt caggtgctcc tcctgggggg
    10021 agtagtgtct cagaagaggt tttgaaacac cgtgcaatgg tggaaaaata tgccaaagaa
    10081 tcggatataa cagagtatgt tccgattctt ttagcgatta ttcaagtgga atctggtggc
    10141 acaatggaag atgtgatgca aagttctgag tcagccggtt taccaccgaa ttcattaagt
    10201 accgaggcat ccatcaaaca aggatgtctc tattttgcgt ctttggttaa gcgttccaaa
    10261 gaattaggtt gtgatcaaga tagtatcatt caggcctata actttggcgg tggttatttg
    10321 gactatgtgg caaaaaacgg gaagaagcat agttttgctt tagctgaatc tttttcaaag
    10381 gaaaaatctt gcggtcaaaa aatcgattac cctaatccca tcgcgaataa ggaaaatggt
    10441 ggatggcgct ataactatgg caatatgttt tattgcttat tggtgaagca atacctaact
    10501 acaacacagt ttgacgataa aacagtccaa gggatttttg acgaggcgtt taagtatgaa
    10561 ggaacggctt atgtatttgg tgggtcaaga cccgaaacag gatttgattg tagtggcttg
    10621 actcaatggt gttatgccaa agttggtctg aaacttcctc gggtggctca agatcagtat
    10681 gatgccatga cccatattga cctaaaagat gccaaaccag gggatttggt tttctttcat
    10741 tcgacttatg atgccggtac ttatgtgacc catgtcggta tttatgcagg ggagaatcgc
    10801 atgtttcatg caggagatcg tgcgagacgt tcctaactga aaaggttagg cagttacaac
    10861 ctcgcaaaaa caaaagttgt aacgagaact gataattcga aaagtcgaat gacggagtaa
    10921 cgccctgaaa ggctttagct aaaactgcga caggcgataa attattaagg atttcatggt
    10981 ctggagctcg cagaagtcga ctgagaagac gccctaatcg tattttgaga atacgaaagg
    11041 aaatgcgaac tagaggtagt cgagtgtccg ataggtcggg cttccataaa atactcatgg
    11101 taagaatgtg cgaaaagcac tgacgaaatt ctgaatgtac gtgtctacac cgcgaagttg
    11161 tctaacggca gctactacaa atcgtagggt ttgtggggtg gagtaaaact ggtcactatg
    11221 aaactcccta tatcgttaca ggcgatatca agcaaacagg cacagaggga ttacctaaaa
    11281 gtatgatgta cggatagaat tatcggaacg tcgtaagctg aaaacacgga tacgcttatt
    11341 cgtaaatgaa gtgtttgtaa ggaaaagctt tgaccataac ttacattaat ttcagtgaaa
    11401 gtggtggcac agtacctacg aaacagtgat aacaagctgt ggagggatag ccactagtca
    11461 acagtaattc aatctatttg actgttcatg aattaggttc gggtaagact aagataggaa
    11521 aacttcatta ttacggaagg aaccaactaa tgacagtcaa agttagtaac aaaaaggcac
    11581 tgaggttcaa tgagtattac gatactcaga aaattcaaga cgaactctat caattatctg
    11641 ccgaaggcag tcatgtgttt agagatttaa tgagctatat cacacaagaa gaaaatattt
    11701 tattggctta tcgaaatatc aaaagcaata aaggcagtaa aactgctgga acaaataaaa
    11761 gaacgattat tgatgttggt gaagaaaacc catatcaatt agttcaatac gttcaaaatc
    11821 gatttaacaa ctttcaacct cactccatca gaagagtcga gattccaaag ccaaatggta
    11881 aaaccagacc gctaggaatc ccaacaattg aggatagatt agtacagcaa tgcataaagc
    11941 agatccttga accaattttg gaagcaaaat tccataagca ttcttatgga tttcgaccag
    12001 aaagaagttc gcaccatgcc atagcgatat ttcagcaatg gacatttaaa ggatttcact
    12061 atgtagtgga cattgatatt aagggcttct ttgacaatgt aaatcatgga aaattgctta
    12121 agcaactctg gacaatgaaa attcgagaca agacatttat ttcaatattg tcgagaatgc
    12181 ttaaggcaga ggtaaaaggc attggaaaat caaccaaagg aaccccacaa ggtggtattc
    12241 tttctcctct tttagctaat gtggtgctaa acgaattaga ttggtggata gatagtcagt
    12301 gggacggatt tccaaccaaa aaaaatacag tagtctgctg agtaaaactc aatcaataag
    12361 aaagtattca aacttgaaag aaatcaaaat tgtccgttac gcagatgatt tcaaaatcat
    12421 gtgcaaagat tatcatactg cccagaaaat tttcctcgca acaaaacaat ggttaaaagt
    12481 acgacttgat ttagacataa gtcctgaaaa gtcaaaagta actaatctga gaaaaaatta
    12541 ttctgacttt ctaggattca agttgaaagt gaaaaaagga aaagcaaacg gatataccaa
    12601 tcgaagccga atgtgtgata aggcaaagat taatgcggta gataaactaa agaacaatat
    12661 caaaacaatc gccgctaatc caactgtaga taatgtcaat aagtacaact ctgttgttct
    12721 aggtttgcat aactattata aaattgcgac tctggtcaac ttagattttg tagatattgc
    12781 tttcacagta aataaaagtc ttgattgtcg aaccaaaaat attcgcaata agcacggaac
    12841 gctaaccagt acctatcaaa aattctataa acaatataac tggaagaaac gattcatagc
    12901 gaacatgatt ttatttccaa tagccgggat aaaatttaca atgccaagaa tctttccgaa
    12961 ggactggaat cgatatacgc ctgaaggtag gctgtttatt catcaaagat taaagatgga
    13021 tatgcatacc gtttattacc tgctggaaaa ttccaatccg aataagtctg tagaatttaa
    13081 cgataatcga atctctctgt tcatagccca acaaggaaaa tgtcatgtta gtggtgaaaa
    13141 tttatcaaaa gataatatgg aagttcatca cattaagccg ttatcacttg gtgggaatga
    13201 taactataag aatcttgtga ttgttacaaa agaaacacac aaattgattc atgcgactaa
    13261 aagagaaacg atagttcatt atttaccttt ggtattaaaa aaggaaagat cattggaaaa
    13321 gctgaataaa ttacgtgctt tagctgggaa tagtgaaata gaaatgaatt actgttgatg
    13381 gaacgccgtg tgaggggaaa ctctcatgca cggtgtgaag cgggggaaaa gatggagata
    13441 acctcaaagt cttacctatc gctatcagta ggctggacga atctaacaga aagctattgg
    13501 cagcagcatc ttatcggtgc tggacggtac aaataagaga aaagaggaaa aagaatgaag
    13561 ataaaaattg aacggaatca aaaggaaaag agcctaaaaa agaaaaaaga acgagtcgta
    13621 tccgtgggta agcatcgaaa aatggtgctt gccctttggc ttttattatc ttgtagtctt
    13681 acttttggcg tttataaaaa tttcaccgcc attgatcaac atacaactca tgaaaaagtg
    13741 gttattaaag agaaagtagt gaatacttct ggtattgaaa actttacgaa ggatttttcg
    13801 aaagaatatt tttcgtggaa aaataacaaa gaagcaattg aaaagagaat gaacaacctc
    13861 gaacagtacc ttacagaaga aggtttcgct ttaagtcaag atatggttcg agcagatatt
    13921 cccactaatt ccgaagttca gtcagtaaaa gtcttagatg ttgaaaagag ctcggaggaa
    13981 tttgtcgttt catttttagt ggagcaaaag attacagagg gaaaaaaggc acaatcgatt
    14041 tcttctgcat accgagtgac gatctttgaa gatgaaaaca ggaattatat agtaacgagt
    14101 ttgccaacta tgattgcaaa acctgatagg gcaaaataca agacaaaaca agtagaaaat
    14161 gattcgaaaa ttgatgccaa aactacagaa gaaatcgctg agtttttgga aacgttcttt
    14221 aaattatatc catcagcttc tgaaaaagaa ttggagtatt atgttgaaaa tgatgcgatg
    14281 cgaccaatca atattgactt aaagttttcg aagttagagg atccagttta cctacaaaac
    14341 ggaaaaaaaa ttctagtgag tacaaagata aaataccttg ataatgtatc aaaaaccact
    14401 agctactttc agtacaaatt aatattacaa aaaaatggaa actggaaaat cattgatgtt
    14461 aaataataat gactcaatct aaatttatga gaagttataa gtagtttaac ttatttcagg
    14521 cagaagtcgc ccatcctcta taggtgggtg atgaatgccg ttcggtaact cgaaaaccga
    14581 caattaagac atagtgcctt tttattttaa tccatgtcat aatcagtcta tataagaaat
    14641 ggttgatata ccatggaatt agatacaaat aatcattcat tatttcttct ttgttaccac
    14701 cttattttag tagtgaaaca ttgtaaacat ctcattgatg atgtaatgtt agcttatgca
    14761 aaaaactatc tttgaaagaa tatcagaatc acatcacatt accttagttg agtgaaatcg
    14821 tgataaagac tactttcata ttatgctcaa agcacaacct aaaaccgaat taacaaaatt
    14881 cagcaatgcc taagctcatg tctgataaaa tgagactttc taagggtcaa aaatttcctt
    14941 tgaatacgat cattagctta gataaaagta aaaaccttag aactacgggg atagcttggt
    15001 taataagaga tatcgctgtt aataaagaca taagcttgca agtatgctct attcccaaga
    15061 atctcccact tcaagcacta aggatcgtta aattcagcta agtggcaagt agttcactag
    15121 acgataatta tctccatatt tcaatctcag cttttccatt tttcatagca aattccgtta
    15181 tttttatagc atctaaaaga ttcagctttt ccactgatct ttcaccactt ttcagctttt
    15241 ttattgtgct taaattgata ccagtacctt ttgatattga attggaagta aaatcattaa
    15301 gggttttttt tattaaattc atatccgcaa ttccagcgtt cataagaatg aagattctcc
    15361 tctcatagac tactttgaaa atggtactac agtggctgtt tatatatttc agtaggttac
    15421 tgtagtggtc attttattat aattagaaaa ggaacctaaa tcaaaaatgc taaagaaaat
    15481 tttcatagta ttaaacctat catgactaaa gccacggaat tcttgataaa agagtatact
    15541 tgcaagccta tgtctttact aacagcgata tctcttatta accaatctat ccccgttgtt
    15601 cctaaggttc ttgatgtttt ctaaggcaat gcttgtatac atagcccttg atcaaaatat
    15661 tgatactaac gttgacgttt cgatcatgat gtgtacggca aataggacaa gtccattctc
    15721 gaattgtgaa tgacttctta ccatctgtgt gtccacattc tgaaccaatt tgactagacg
    15781 gaaatcattt atctatcttg atgatttttt tgacagaagt atcgaaaatc tttacataat
    15841 ctgggtgttg cattcttatg cagatgagag cgttagctcc gtattcataa ccagttgcct
    15901 ctaaaacgta gtccatcggt ggatacctag cttgcggttg ccagtggctt tcgcagtctt
    15961 cttgtaatca aatcgagcat ctaattgagt actagtattt tgaagataat acttgagttt
    16021 ttcggttttc agaagttcac ttcatcttcc atcatccatg gaaatcccac tcacccatac
    16081 gcaggcctcc aaaaattctt caacaatggt ttttcagaca tttttctgaa tacctccttg
    16141 ttttttgata cgccagatag tcaggaaaaa ggcaacaaaa cacaaaacaa agctgcctaa
    16201 aaaggtaatc ttcattccat ataaaaagac atccggccga tctgcgatat agttagttac
    16261 tcgttggccc atcttagcag acatcgcttg atataagacc gtcgtagaaa gcgaaatccc
    16321 gatgaccatc cccaaatttc gggcaaagga attcatggag cctgccagtc ccaaattttc
    16381 gatagtgaca gaactcataa ccatcgtatt atttggggac tggaacaagg cattgccggc
    16441 acccatgatg gcagtagcga caatgtacag ccacaaagga gagtccactg acaaaaacat
    16501 atacatgact tgggttaccg acaataaacc caagcctact aatacaaaaa tctccgggcc
    16561 aacccggtcg gtcaggtatc cgcttaaagg cgccccgacg accatcatca agggaaagac
    16621 catcatcaac agtccggcat agctaggact caacccgcga gcattttgca gataaaaagg
    16681 aatcactaca ttaacaaaga agttggaaga aaaaatcaac aaggctgtaa tcaagctcat
    16741 ggtaaaaatc ttgttcttaa aaataccgaa agaaatcaat ggagaggctg ctttcttttc
    16801 aacttttaaa aagctgacaa aggcaatcac tgaaattacg aacagtacaa gggggactgg
    16861 atggaaaaag ccactttctt gccccaaaaa gattgttcca aaaaggctga taatcgtagc
    16921 cgcaatggca gcaaagcccc ctccatcgat tgtatggccg ctcatggtga tatcttttgg
    16981 taagaatttt tcagcaatca acatcgttac gattcccacc ggtacattga tccaaaaaat
    17041 gtacgcccaa gaaaattggg acaaaatcaa gccgccaaga cctggtccag caatcgagcc
    17101 taatgaaaca agcgcaccga ttgctcccaa tgcccgacca cgttcatgta tgggaaagac
    17161 ttccgtgatg attccggcat ttgtagccat agtcatacta gcaccaatgg cttgtaccac
    17221 ccgtgcgaac aattaaatac ctagcgaatg attgaaccca cacaacagcg agcccaagac
    17281 aaagatcagc gtaccaatcc gaaatacttt gattttccca cagctatcgc caattttacc
    17341 aaacagcaac aaacaagaac agacaatcat cagataaacg gacactaccc attccgcttg
    17401 attcattggt atgcccatat catctgagat ggtaggtagt gcaatattga caatactgcc
    17461 atccaatgtg gacatgaagg taaacataga tatagcaatc aaaatccacc agcgattttt
    17521 ttggactttt gcatcttctt gataactatg cataatagga tttcctttct aatgatcgtg
    17581 tagctaagaa caatataacc tatgtctact gcccaacaac ttctcgcgac tctagccata
    17641 ggaagcttga gtaatttcga tttgttattc tcatgtaacc atgtaagttt gagatgcttt
    17701 atttgaactt actctatagt aactagtgat aattcgcttt actttcttct agcaatttct
    17761 aaaagtcgac ttcattgttc ttcagattaa tagtgtgagc tatctcgtga gacgtaagaa
    17821 aatttccatt ctactttttc ccaatttttt catatttatg gtgttgcacc tatttgtttt
    17881 ccaatttgct tttcaaatac attgctatga tattcaattc cataggatta tactaaatgt
    17941 caatagtatg aataatatat tatagatgtt tatatatcac tgttaattat tatccacaat
    18001 aattaatgat tacctcgata tttgtcaatc aaaggttgaa acaatttatt ttcagcatct
    18061 tttctaactt gagctgcact cttaatagaa tcatacgatc ctaaatagta cctctttttt
    18121 ttaaagttat atacgcaatc catttctctt tagaacgata aactccctta acaccacttg
    18181 tattattttt cggtaatttt gacgttagac actctattac tgtcccttca acacatgtcc
    18241 ttgtttcttg cctttttaaa catccacaac tttgagtatg tccaaaaaat aagttactat
    18301 aacttatctc acacatactg ccacactcac attgacaaac ccattttgtt ttccatgaac
    18361 agttattgtc caaaggatac tttgcagtaa gtaatccgaa ttttttattt tcaatgtgat
    18421 gcttttttga tttcaaacat ccacagcttt ttacatcacc ttttagaagt cgctttgccg
    18481 atactaactt ttttctccca cacagacatt gacattccca aacaacagtt ccttcacttc
    18541 gcagtttagt tggcttgatt gcaactaact taccaaaagt tttatttgtc aaatttttat
    18601 atttatgcct atttttataa tttccacatc cacaactttt ggttctacct gatagtaagt
    18661 ttgatcgata tacaatcgtt tcattcccac agtcacatag gtaacgatat tttttatatc
    18721 cattatgagt aatctcctca acaacagtaa ggtgaccata tctttccttc actgcaccta
    18781 ccctcccaag aaagaagtac catataattt caattaactt ttaataaatc agaaaaaaat
    18841 attttcaatt tttcttagtc tgattttatg actaatttat aatacaagac tgaacgatac
    18901 gtacacgaaa tcctcaagat agataaattg ttttcatcta gtaaaacctg ctcaaaatat
    18961 gagcataaag acggcaataa tacactcgat attcgataat ggacttgttt tatttgtcaa
    19021 actcatcgta atcgagatat caattccagt ctcaatatcc tgatcaaagg tctaagaatc
    19081 caaccatttt cttgttactt tgtcagattg attacctttt ttagtctccg aataataagg
    19141 ttttcggatc aactaacatg ctctgagaaa gactactatc tttgcaaatt tccaaatgaa
    19201 ggtgtgggcc agtactattc ccagtacttc ctacatagcc aattatttgt ccttgcaaaa
    19261 cattatctcc agtttttact aggtattgtt gctggtgagc atataacgcg gttgatccat
    19321 cttcgtgttg tatcaccacg taatttcccc aagagtagtg aaactctgct ttaacaacct
    19381 taccagcttt aactgcatga atcggctcac cctgtgtagc tgccatatca agtcctcggt
    19441 gaaattcatt tccacgattt ccaaacaaac tggttattga ataattatga ataggcactt
    19501 ggtatccagt cttactcatt tgtggacctt taacttcttt atcatagttg gttaaatcat
    19561 aggttttaat taattcattt agcttcaaat agtattgtgt atctgttgca taccgtcctg
    19621 taaggaattt agttgcttct cgatatgttt tactattagc ttttaatgct cctgcataaa
    19681 aatctttatt tccactaatt cccttagtta ataatttggc ataatcttca aaactttcct
    19741 catagttttc atacactcta aattttgatt gggtcgtata aagcgttcca ttacccaaat
    19801 cttcgtttgt taccataatg acaaagtttc cattataagt tccttttatc ccaaataaat
    19861 tgtaattcgg tgcctgagct aactggcttt gaccactggc agattctaag atcgcttgtg
    19921 caatcataac agaagcatat aaatcatatt tctgaccaat ttttctcgca gactcaccaa
    19981 ttttcataat aaaattttct acagattcat ttttgtcaaa atgaatttct tcattaccag
    20041 atagtattgg ttgtgattgg aaagattctg ttgattctat ttgctgtggt gtcgaaaaat
    20101 tttttgtttg tccttccgtt tttggcgctt ccttttttga agactctata tggtttggtc
    20161 ttgtcacttt cgaagaagtt atttcacttg tactacttga agttgttgaa gattcggcac
    20221 ttgaaatcgt actactttca cttgacgaag ttgttgaaga ctcggcattt gaagtcgtac
    20281 tactttcact tgacgaagtt gttgaagact cggcatttga agtcgtacta ctttcacttg
    20341 atgaagttgt tgaagactca gcatttgaag tcgtactact ttcacttgat aaagttgtca
    20401 aaagttcact actctctgct gttacatcgg aattactcat ttcagtcgtc tcggttcttt
    20461 cttttgcaat tttgtatgtt gaattttcgc ttgccaacac atggaaaggt gttgctataa
    20521 agagttggga cattaatata actgctgatg caagttttaa agattttttc atttgattta
    20581 cctctctttt ttctctttaa tagtgttttc tattaaaaat tatgataaat attttcaatg
    20641 aattgagtaa tacagtatat ttcttgattt catttagtaa cgattatgtt tcaatgttta
    20701 atcctgttac tgcctttaaa ataaaattat agggttggct aaaactagga tgaaataaat
    20761 aatctaacat tttcaatttg tctaatgtaa tttgttcttc tatagcaaga gaaaacattg
    20821 ataatagtcc agataaatct tcttgactac aaagttgtac acctactatt ctctttgtat
    20881 ttttttcaaa gctaattctt aattttacac gactattttt tctcaaaaaa acaggtctaa
    20941 tgaaatcttc tatttctata taatctatag actcacttaa taatcgtgct gtttttaaat
    21001 tcaaacctgc tgcgtaaaaa ttgtaattaa atatagaaaa gccatttgta aattgggaac
    21061 cagaaggtgt aaaatcttga ttgtcaatat gttgagttgc aatataagct gttcttagag
    21121 cattagaaat agaaaaatca acactacttc tattaatgga cgtaaaaaaa gttgtagcac
    21181 aatccccaat agcatatata tcttttatat ttgtttgctg gtattcatta gttagatatg
    21241 ctccactaac atctctcaag agttcctttt tgccaattgg actattagat agaaatccta
    21301 tagcttgtac gaccatatcc atagagtatt gggtaccact tgtagtgact attttttcaa
    21361 tcttttttct tcctaaatat tttttaggac tttctgatag acaaagatgt attccatttt
    21421 ttgatagtat ttcttcaact ttatctgaaa aactacggtc gtaataagtc gacaacactc
    21481 tatctgcaac atcgaaaaga tatacttctt tccctctttt tcttatggct tcagcaattt
    21541 caactccaat atatcctgct ccaataattc ctactttttt aatagtatta tcatctaaag
    21601 ctttaaaaat ctctttagca tttggaaaat tctttatcga aaaaatatta gctaaattat
    21661 tccccggtac atctaacata atttgctttg aacctgtagc tagtataagt ttgtcatatt
    21721 cttgggaaaa tcttgtgcca tcttttttta cacaaataat ctttttattt tgaatatcaa
    21781 ttttgtcaac tgctgtctcc aaaaacaact tttttatctt agaatttagt tctcttctat
    21841 tttgataaaa aagatcttct aaattgctaa cttctctttt tatgaacaac gatgtcccac
    21901 attctaagta actaatttct gattttttat ctatcagaat aacttcataa tttgaatcac
    21961 ataagtttag aaatcgagct gcagctagcc ccgaatggtt tgatccaata attactattt
    22021 ttttcactta atcacattct tttcccttct atgaaaagta tcttcatttt taactaacaa
    22081 cctatctccc aaaataaaaa acaaaaagag gaagaaaaag attcttcctc ttttcagaga
    22141 agatttaaga aattgatttt ctattcattc tctttttttc gatttttata ccctaataac
    22201 cctaaagttc ctaacaggat taaaccacca ctaatagtaa agatattact atcaatctct
    22261 cccgtcttag gataagcttt tgaggactgc ttttgaggac tgcttttgcc tctatttttg
    22321 ttttgcttgc taccttgatt gtcagtctta ttatctttac taacggcttt ttcactgtct
    22381 ttttcgtttg aagaaacaac tacattagta ggttcactag tattaccaga ttcatcagtt
    22441 gcagttacta tcacttttgt tcctgcctct aatttaggaa ctttaactgt aaaattacca
    22501 tttttatcag ctgtcccatg gtattgactc ccgtttggta atgtaactgt cacctctgca
    22561 tttggttcag ttttaccagt aacaatttgg tcaccctctg taataggatc aacttgaggt
    22621 ttattcggtg cttttttatc ttctacagaa atagtaacct ctacttcttc tttagatcca
    22681 tctggatatg ttactactac aatccctttt ttgtttccag ctgtactaac atctactttc
    22741 tctttccaag tataagtagt tccttttggt agatcttctt tgttcttaat tccctcagat
    22801 gcgtctggct ctttatttaa gtctgtagtc actttttgtc cttcaggatt gtatttatcg
    22861 gcatc
//
LOCUS       DAXQKX010000045        22209 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.046, whole genome shotgun sequence.
ACCESSION   DAXQKX010000045 DAXQKX010000000
VERSION     DAXQKX010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22209
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.046"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..655
                     /locus_tag="ACF3MF_001882"
     CDS             <1..655
                     /locus_tag="ACF3MF_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927863.1"
                     /translation="LKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGEIYQAEG
                     LSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTAAELQKQ
                     MRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSIQFPQLI
                     TMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVAMEKAN"
     gene            714..1154
                     /locus_tag="ACF3MF_001883"
     CDS             714..1154
                     /locus_tag="ACF3MF_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927864.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            1166..1834
                     /locus_tag="ACF3MF_001884"
     CDS             1166..1834
                     /locus_tag="ACF3MF_001884"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HFE3927865.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            1898..2521
                     /locus_tag="ACF3MF_001885"
     CDS             1898..2521
                     /locus_tag="ACF3MF_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HFE3927866.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            2577..2963
                     /locus_tag="ACF3MF_001886"
     CDS             2577..2963
                     /locus_tag="ACF3MF_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HFE3927867.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            3176..4567
                     /locus_tag="ACF3MF_001887"
     CDS             3176..4567
                     /locus_tag="ACF3MF_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HFE3927868.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAVAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            5178..5546
                     /locus_tag="ACF3MF_001888"
     CDS             5178..5546
                     /locus_tag="ACF3MF_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HFE3927869.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            5726..6667
                     /locus_tag="ACF3MF_001889"
     CDS             5726..6667
                     /locus_tag="ACF3MF_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HFE3927870.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            6736..7467
                     /locus_tag="ACF3MF_001890"
     CDS             6736..7467
                     /locus_tag="ACF3MF_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFE3927871.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            7611..9791
                     /locus_tag="ACF3MF_001891"
     CDS             7611..9791
                     /locus_tag="ACF3MF_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HFE3927872.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            9811..10293
                     /locus_tag="ACF3MF_001892"
     CDS             9811..10293
                     /locus_tag="ACF3MF_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HFE3927873.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            10309..11070
                     /locus_tag="ACF3MF_001893"
     CDS             10309..11070
                     /locus_tag="ACF3MF_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HFE3927874.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            11201..12535
                     /gene="murC"
                     /locus_tag="ACF3MF_001894"
     CDS             11201..12535
                     /gene="murC"
                     /locus_tag="ACF3MF_001894"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HFE3927875.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            12842..13327
                     /locus_tag="ACF3MF_001895"
     CDS             12842..13327
                     /locus_tag="ACF3MF_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MaoC/PaaZ C-terminal domain-containing protein"
                     /protein_id="HFE3927876.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            13320..14003
                     /locus_tag="ACF3MF_001896"
     CDS             13320..14003
                     /locus_tag="ACF3MF_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HFE3927877.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            14129..16774
                     /gene="polA"
                     /locus_tag="ACF3MF_001897"
     CDS             14129..16774
                     /gene="polA"
                     /locus_tag="ACF3MF_001897"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HFE3927878.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            16819..17655
                     /gene="mutM"
                     /locus_tag="ACF3MF_001898"
     CDS             16819..17655
                     /gene="mutM"
                     /locus_tag="ACF3MF_001898"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HFE3927879.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            17619..18248
                     /gene="coaE"
                     /locus_tag="ACF3MF_001899"
     CDS             17619..18248
                     /gene="coaE"
                     /locus_tag="ACF3MF_001899"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HFE3927880.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            18300..18632
                     /locus_tag="ACF3MF_001900"
     CDS             18300..18632
                     /locus_tag="ACF3MF_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFE3927881.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            18944..19435
                     /gene="nrdR"
                     /locus_tag="ACF3MF_001901"
     CDS             18944..19435
                     /gene="nrdR"
                     /locus_tag="ACF3MF_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HFE3927882.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            19458..20831
                     /locus_tag="ACF3MF_001902"
     CDS             19458..20831
                     /locus_tag="ACF3MF_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFE3927883.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            20831..21757
                     /gene="dnaI"
                     /locus_tag="ACF3MF_001903"
     CDS             20831..21757
                     /gene="dnaI"
                     /locus_tag="ACF3MF_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HFE3927884.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            21886..>22209
                     /locus_tag="ACF3MF_001904"
     CDS             21886..>22209
                     /locus_tag="ACF3MF_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927885.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDIN"
BASE COUNT         7522 a         3847 c         4850 g         5990 t
ORIGIN      
        1 tttaaaagat actctgattg agcgatctac atttctatat gttcaattgc aggaaaataa
       61 aacattgctg catttttcac cagagttcca tctagagggg ctaacattag gagaaatcta
      121 tcaagcagaa gggctgtcgg ctgttttgca cttttttaag gtagaattgg aattaccagt
      181 aaaagattat atcgagcttt ctcttgaatc ttgggatcga gcagtggttg aactgtttcc
      241 agaaggttta atgatcgata caaacgatgg gaagatccat ctgactgcag cagaactgca
      301 aaaacaaatg cgttatcaaa tagatgacga aaattctttt tctattttta gacgtcagca
      361 aaagattcta aaaagctttt taaaagtgat cagtaaaaaa cggaatctga tcaaaacgac
      421 acagctgttg aaaaaatatc caggtctgct tcacacgtct attcaatttc ctcaattgat
      481 tacgatgatc catcgtttta tacgtatgca acagctacca tctaagaagc tgtttcttcc
      541 attgacggac acatttcgag tagtcaacag agaagataaa aagaaagtga ttgtgattga
      601 ctttaccaga aatcggaatg tccttcacca agttgcaatg gaaaaggcca attaaggctt
      661 tttctttttg gatttttttg tcataataaa tattagatga tggaggagat aatatgatgc
      721 aaacatggtt agaaaggcta atacgatttc agcagaacta tcacaaactt atgcagggaa
      781 gatatgcgaa atttgatcag ttgaatcgcg gtctattgat cgctgcgctt gtctttagtt
      841 tgctaagtcg ttggttgccc tatagaatcg gacaattgtt gttcatcgtc tttttcggat
      901 ggatgatatt tcgtttccta tcaaaaaaaa tctaccccag actaaatgag aatcaacgtt
      961 atttgaaata tcttgataga gtcaaagaaa aatatcatca gataaaaaac aaaaagcaag
     1021 tcaaaatgga tcgaaaaagt tatacttttt ttgagtgccc gaattgtcat caaaagcagc
     1081 gtgcacctaa aggaaaagga cgaatacgtg tgacatgcaa aacatgtggt ataaaattcg
     1141 aaacgaatgt ttaagggaga aaagaatgaa attagtatta ttacgtcatg gcgaaagcga
     1201 agcaaatttt gaaaattact ggacaggatg gctagatgtc gccttaacag aaaaaggaaa
     1261 agaacaagca gcagttgccg gtcaaaaaat gcttgaagcc ggacttcaat tcgatgccgt
     1321 ttatacctct gttttgaaac gtgcgattct taccggacaa gtcgcactag aagaaatggg
     1381 tcagttatgg cttcctataa taaaaacatg gcgtctaaat gaacggcatt atggggatct
     1441 tgtgggtaaa aacaaagata agatgaaaga aatatacgga aaagatcaag taaaaacatg
     1501 gcgcagagga tatacggaag ttccgccgtt aaccgcagaa aatagatttg accgcagata
     1561 tgatcacttg gatccgcatt tgatcccata cggagaaagt ctggaaatga cagtgaatcg
     1621 gatcattccc ttatggcaag atcatctagc accaaaacta aaagatcggc aagatttact
     1681 agttgtgggt catggtaata gcatccgagc actgacaaaa tatttagaag atgttcctga
     1741 agatcaaatg gatacgatcg atatcccaaa tgcacaacca atccagtata cattagcaga
     1801 tgatttgaca attctggaca aaaaaatact ttaaagaaca cctttatcta aaagtgagag
     1861 atagaaaaaa gaagcaaagg aatggaacaa aaggaacatg aaaaattata tatgggactt
     1921 tgatggtaca ttgtttgata cgtatcccgc aatggtagat ggtgcatggc aagcactaaa
     1981 agattttggt atcagtatgg acaaaaaaga aatctacttc aaaatgaaaa agtattctac
     2041 tagttatttg atcaatgaat caaacttgaa tgccagagag tttaatgaat tatttcaccg
     2101 atatgaaaaa gaaagtacgg aagtttcccg tccatttcca gaaacgaaac aagtactgga
     2161 aatgctaaaa gacaacggcg gtcgtcattt catcctgacc caccgtttga cagaatcaac
     2221 atggggcctg ttaaaagaac atcgattggc acatctgatt gaggaagtag tagggatcga
     2281 tcaggacttt cctcgtaaac ctgatccagc atctttaaat tatttgatcg atacttttca
     2341 tttagaaaga acagacacga tgatgatcgg cgatcgtcgt ttagatatcg aagcagggaa
     2401 aaatgcagga gtcgctactt gtctttacga catcgatcat tttctgggtg agatcccggc
     2461 agattatgtg gtaggaaatc tgaatgaaat ccttaccttg cagagcatca ttaaaaagta
     2521 gtatcccctt tcaaaggaga tatgttataa ttttcataaa ggagtgataa aattatatgg
     2581 aaatcagaag acaaaaagaa gttgtagaag catttcatta tgatatgaga ttgccgaacc
     2641 aagaagtaga aacagatttg aaagtaggct tctcgccttt aaaagaaacg atcgaaaact
     2701 atccgaaaga acatagcatc gtaggagcac gcttagagtt ccgtttagtg tttgatacat
     2761 atgttttatc tggaagtgtg agtcagatca atcatatcct caatcggaaa attgaaggtc
     2821 aaaatgatgt cacacaagaa gaagtggacg agctagtagc accgttattc gatatcgtac
     2881 gccgaatgtc ttatgaggtg acagagatcg ccttagatca gcctggggta aaattgaatt
     2941 ttcaatcaga aaaacaagaa tagacagtaa aaacatacct gcgatagatt aaagctatca
     3001 caggtatgtt tttttattac taattgtaag caaaaagaat gtcatttcga taaaaatcgt
     3061 ctaaaatata aaagtcactg aaaaaaattt tttcaggagg atggttgaag aatcattctc
     3121 gggaaccttt acttccttcg atggacttgt cattaataat atgaggagga gaaaaatgac
     3181 aacactcatc acagttttag tggttctagt ttttgcggca ttattatatg tgttctatcg
     3241 tatgcaaaag cgccatacaa aattttcaac acgcgtcttt acagcattag gagttggtat
     3301 cgtctttggc ggtctgcttc aattgatctt tggtgtagac gacaaagtcg ttactcaatc
     3361 aatggaatgg atcgggattg taggtcaagg atatgtatca ttcttgcaaa tgctagttat
     3421 gcctttagtg tttatttcga tcattggtgc attcacaaaa atgaaagttt ctgaaaagct
     3481 agggaaaatt agtgcgactg tattgacttc tttacttgga acaacagctg ttgcagcatt
     3541 gatcggaatt ggttcaacaa tgctgttcgg actccaagga gctaaattca cacaaggagc
     3601 tgcagaaaca gcacgaatct ctgaactggc aacacgtcag gaaacagttg aaaacttatc
     3661 gattccacag cagattttat cctttatccc taaaaacgtt tttgctgatt tagcaggtag
     3721 tcgtgcaaca agtacgattg gagtcgttat tttcgcggca tttgtcggaa tcgcttatct
     3781 aggcgtgaaa agaaaagcgc caaaagaagc agcattcttt tcagatttag tcgacagtct
     3841 gtataaaatc attatgcgga tcgtgacgct tgttttgcgt ttgacacctt atggagtatt
     3901 tgctttgatg acaaacgttt tggcaacaag tgattttgca gctatcgtca atttaggtaa
     3961 atttgtcgtt gcttcttacg tagcattgct tgctgttttg attgtccact cactgatttt
     4021 gattggtgca aaagtcaatc caatcaacta tttcaaaaaa gcctttccgg tattgagctt
     4081 tgcgtttact tcacgttcaa gtgctggagc tttgccattg aatatcgaga ctcagacaaa
     4141 agctttagga gtagatgatg caacagctaa tttctcagca agttttggtt tgtctattgg
     4201 acaaaacggc tgtgctggcg tttatccagc tatgttggca acgatcgtcg caccagcagc
     4261 tggagtgaat gtctttagtt tggaatttat tttgatgctt gtggcaattg taacaatcag
     4321 ttcttttggt gtagctggag tcggtggggg cgcaacattt gcttcactga tcgttttagg
     4381 ggcaatgaac ttgccagtag caatcgttgg gttagttatc tctgttgaac cattaatcga
     4441 tatggcacgt acagcagtaa acgtcagcgg tagcatggta gctggtatcg tgacaagtgc
     4501 acgcatcaaa gatttagatc gcgatgtcat caatgatgat tctaaagtga tcgatgtgaa
     4561 tgcatagtca aaaagaggtt gtgatagaag tggtcagctt taagaaataa gaagaagttt
     4621 cctaaaaata gtttctcaaa tttttgtgaa atttcggctt atttccgaga agctacttct
     4681 gaaacaccgt gaataagagg ttgtgaaaaa gctgccctgc atcaagtaat aagaacagcc
     4741 aaacaaaaat agttcctcat attttacgtt tggttgagct tattaccgca gatgcaagct
     4801 tttgaacacc gtttaagaaa gaggtcgtga gcctgccgtt tcactctgag tcacaaagag
     4861 caatttcaaa aaatagcttc tcatgtttgt tgaatattgt gtcttgtgac cgaggagttg
     4921 tcaggagaac accgtttacc agaggttgtg acttgttttt agtcacgacc tcttttttta
     4981 tttattccat ataaatacac attatttatt ccgaaaagtg aaagcgcaaa taacaaaaac
     5041 aaccaactta tttattatta aagaaaagcg tatttaagta ggacgattct gttgagagct
     5101 ttcgtagatt ttcccatttt cctatggtaa actgacaaag ttgagaatgt tagaacagat
     5161 cgtttaggag gaaacagatg tttacgaatg aaataaaaat catgctttat gtggacgatg
     5221 tagaaaaaaa tgcaacgttt tggagagcag ttggctttgc ggaaaaagat cgtcaagaaa
     5281 tggatgggac gcttataatt gaagtaggag ttgaggacag tcaaacctca tttctgttat
     5341 atgatcgagc atttgttgag tcccattcac ctggcacagc tactagtgcc ccatctttga
     5401 tgttttacag taaagatatc tttggactat ataaaaaaat gcagacgcaa tcagtcacat
     5461 taggtgatat ggtacagctt ggagaagaat atgtctttaa ctttgctgat cccgatggca
     5521 actactttgc ggttacaggt aaataataga aataaagact ttgtttttct gtgcgaaaca
     5581 ggaaagcgaa gtctttttaa ttcaaataat aatattatgt aaacaaaaaa ctttccatgc
     5641 gtaattatac acaagcaaat aaatcgtcaa atgcgaacgc cttctttata ctgtttagga
     5701 acgaaaagaa ggaaggaaga aatacatgga ttatcaagta ctgctttatt acaattatac
     5761 aaaaatcgaa gaaccagagg aatttgccaa aaatcattta gccttttgca aatctttgga
     5821 tcttaaaggt cgtattctag tagctgaaga aggaataaat ggtactgtgt ctggaaccgt
     5881 tgaaaacacg actgcctata tgaaagcaat gaaagctgat cctcgatttg ctgatacgat
     5941 gttcaagatc gatccaagcg aaggacatgc ctttaagaag atgtttgtaa gataccgtcc
     6001 agagcttgta agtttaaagc tagaagagga cattgatcca aaccaagtga caggtgccta
     6061 tctttcaccg caagaattta aagaagctat tttagatgaa cagacagtgg tgattgatgc
     6121 acggaatgat tatgaatatg acttgggaca ttttcgaggg gctgtacgcc cagatatacg
     6181 cagttttcga gagcttccag actggatccg cgagcacaaa gaagaattta tggaaaaacg
     6241 ggtagtgacc tactgtactg gtggcattcg ttgcgagaag ttttctggtt ggcttgtccg
     6301 tgaaggattc aaagatgtcg gacagctgca tggcggtatt gctacttatg gtaaggatcc
     6361 tgaagtccaa ggagaattat gggacggcaa gatgtatgtg tttgatgaac ggatcgctgt
     6421 cgatatcaac caagtagata aacaaatcgt cggtcgcgac tggtttgacg gaacaccatg
     6481 tgaacgatat atcaattgta gcaatcctga gtgcaatcgt cagattcttg cttccattga
     6541 aaatgaagaa aaacatttag gagcatgtag catagagtgt gcgaaacatc cgcgcaatcg
     6601 ctatgttcaa gaccatggaa tctctccaga agaagcagaa ctgcggttta cagctttaat
     6661 taaatagaaa acaatagttt tgattgtcga ccatttccaa tatgcgctat actagcgttg
     6721 aggatggtga tccacatgaa atcattgatt tatgctattg gggatgtcca tggcaaacat
     6781 gagctttttg aaaaacttat tcactattat gatccaaaga tccatcagct tgttttatta
     6841 ggggatctca atgatcgagg tcctcgtaca aaagaatgtt ttttattagg aaagcaatta
     6901 gtcgaagaaa caggagccat ttacctccgg ggaaaccatg aagaatattt tttgcaattt
     6961 ctgcaatcac cggaggactg gtatgcgcct tatatgagaa atggtggaaa agaaacgttt
     7021 gaaagcctga ttcacccagg ggcatcggag gaatactccc caactgaaat ctcgatgatg
     7081 atccaatcga gatattcaga actgattaaa tttttagtcc agcgcccctt gtattatgaa
     7141 tgggaaaatt atctttttgt ccatgccggt gtggatttga caaagaaaga ctggcgtaag
     7201 acaagtctaa gagactttat ttggataagg gaaccatttc atgaagggaa aaacaataca
     7261 ggtaagacaa ttgtatttgg acatacgatt acaccaatgc tccatggaga tatgcagaca
     7321 acagacctct ggattcagga tcataaaatc ggaatggacg gtggggctgt attcggaggg
     7381 tcattgcatg gggttgtttt tgacaaggaa ggtattcttc aagatattga atatcagaac
     7441 aacgaaggac cttggcatgg aatctgacta atggaaagaa tgaaggagct gtgactttgt
     7501 tgcggctctt tttattttta tagagaatat tgtttctttc agtagtttaa cccaggataa
     7561 aaagtatgat agaataaaga agcaattttt agcagaaaag aggcatttta atgacggaaa
     7621 atttgaacca gacgatcatt cagcttgtac aaaaagaact ttcagactat cgtcctaagc
     7681 agttgactac tgtacttaat ttgttaaatg aaggaaacac tgttcctttt atcgcgcgtt
     7741 accgaaaaga aatgactgga agtcttgatg aagtccagat tcgtgaaatc gaagagcggt
     7801 atgcctatct tgaaaactta gaaaaacgta aaactgaagt gattcggcta atcgatgaac
     7861 aagggaaact gactcccgag ttagaagcag aaatcaccca agccgtgaaa atgcaacaag
     7921 tggaagattt gtatcgtcca tacaaacaaa aacgacggac aaaagcaacg attgctaaag
     7981 aaaaaggact tgaaccactc gcgaagtggc tgatgcagct tacagatgga gaggtgcaat
     8041 ctgaagcaga aaaatatatt gacaaagaaa aagaagtctc ttctgccgaa gaagcgttgc
     8101 acggtgctca tgagattatt gctgaacaag tcagcgataa tgcaaaattt cggacttgga
     8161 ttcggtctta tacgtataac aaaggtatgt atgtcagcaa tgtcaaggat gagcaagcag
     8221 atgaaaaagg cgtatatgaa atgtattatg actttgcaga acccgtccat aaaatggttt
     8281 ctcatcgaat attagctact aatcgtggag aaaaagaaga tattctgaaa gtattctttc
     8341 aagtagatga agcagcaatt ttagcttact tggatcgcca aatagtcaaa aatcctgcct
     8401 ctccttcttc ttcattcgtc agagaagcct atcaggatag ttataaacgc tttattcagc
     8461 cagcaatcga gcgagaactg cgcaatgaat tgactgaaaa ggcagatgag caagcaatcg
     8521 ctattttcgg cgaaaacctc cgtaatcttt tgttgcaacc gccactaaaa ggtaaagttg
     8581 tcctgggatt tgatccggct tatcgtactg gatgtaaact agcagtcgta gatgcgacag
     8641 ggaaagtttt agcaatcgaa gttatttatc ctcataaacc tgcagcgcaa gcaaaaagag
     8701 aagctgctgg accagctttt atccaattaa ttaataaata tcaagtagat atggtagcta
     8761 tcggaaatgg tacagccagt cgggaatctg aactttttgt ggctgagcag ttgaaatccg
     8821 ccgaccataa aacctattac gctatcgtca acgaagcagg cgcttctgtt tactccgcta
     8881 gcgaaattgc acgaaaagaa tttccgcatc tacaagttga agaaagaagt gctgtttcta
     8941 ttgcccgtcg cctgcaagat cctttagctg aattagtcaa aatcgatcct aaagctgtcg
     9001 gagtaggcca gtaccaacat gacgtttctc aaaaacgttt ggctgaacaa ttggattttg
     9061 ttgtggaaac agcggttaac caagtaggtg tggatgtgaa tacagcaagc ccgcagctct
     9121 tgcagcatat atcaggattg aataaaacaa ctgcccaaaa cattgtcatt tatcgtgaag
     9181 aaaacggaga attcaccgca cgaactcaat tgaaaaaagt gccacgctta ggaccaaaag
     9241 catatgaaca agcaatcgga ttcttgcgag tccctggtgg gaaaaacatt ttggacaaca
     9301 caggtatcca tcccgaaagt tattctattg caaaagaaat attaacttca gtccaacttt
     9361 cagaaaaaga gcttggtaca gaagaagcag tagaaaaatt gacacgatta tccgtagaga
     9421 aactggctga aagcctatca gtcggagaag aaacgttagc cgatatttta gctgggctga
     9481 cacaacctgg acgagatatg cgtgatgaga tgccagcgcc cttattacgt acagatgtat
     9541 tgagtatgga agacttgaaa ccagggatgg aattgactgg aacggtccgt aatgtcattg
     9601 acttcggcgc atttgttgat atcggtgtga agcaagacgg acttgtccat atatcgaaac
     9661 tcagcaaaaa attcgtcaag catcctacag atgtcgtgtc agtaggagat atcgtaacag
     9721 tttggataga acaagtcgat acgaaaaaag gcagaatcag tttgacgatg ctttcccctt
     9781 atgaagagta acaatgagga gtaacaaaaa ttgacacaag aagaactgca gcagttagta
     9841 gaagagatat cattaaaaag cttccagctt cctttcaagc accaagcaat gttcaatcca
     9901 cgcttacgta caactggcgg gcgctatcat ttaaacgatc atcatttaga ttttaatgcg
     9961 aagctatttg aagagtcaga cgaagagacg attgcaggaa tcatcaaaca tgaactttgc
    10021 cattatcatc ttcatctagc tggaagaggg tatcagcata aagatatgga tttcaagtat
    10081 cttttgaaaa aaacaggagg gttgcgctat gcaccagcct tgacgaagaa acagataaag
    10141 atggagtatt atcgatgcca agattgttct gccacgatct gccgcaagag aagaatcgat
    10201 gtacgcaaat atcgttgtgg aagatgtcat ggagaaatca aatggattga gacaaaaaga
    10261 gaagacttta atgaagcaca aaaaatcaga tgaaaggata gaaggccttt ggaaaaaagt
    10321 gagcagagga atctaaaaga ctggaatcag ctattaaatt ttttagccgc acctgaagag
    10381 ggaaattttg aggaactgac ggcacctaca cttattttag ctggaaactg tcttcctatc
    10441 ttagctgata aagcagcaca aatgtattta aatggccaag tagatcaatt gtttttggtc
    10501 ggaggggtgg ggcatgcgac tagaatcctt tatgagaatt ttgaaaagca aggatttcat
    10561 tttgaagatg gcatgagtga aagtgaaatc tgtcgtcagt atctaaaaga agtctatgat
    10621 ttgcccgata aggcttttct gatagaatcg aagtctacaa attctggaga gaacgccact
    10681 ttttcactgg agattcttca ttccttagga gctgtaccag aaaaaatctt attgatgaat
    10741 gatccgacac tgcaacgcag gactcgagca acttttgaga aagtatggca aaatgaacaa
    10801 actattttcg cgaatgctgt gccatttgtg ccggaaatcc ttcacttttc tgaagagatc
    10861 atctttacag caaaagaact gaatcatcaa tggcctaagg aatatttcca tgcgctagta
    10921 ttaggagaaa tggaacgtct ccatgacgat gagaacggct atggtccgaa aggaaaagat
    10981 tttattcctc acattgatat atcagaggaa gtttggtctt cttacaccag aattaaagag
    11041 tcaataaaaa cggatttttc tcgtacttga ccattttagc aagcgaatcc tcctttccaa
    11101 ataaatttgg ttgaaatttt caatcgttta taagataatg aggagcgtgt tgaatgtaat
    11161 agctaaaaga atggacgcta gataagagaa gaggattcaa atggaaaatc aaaataaatt
    11221 gtatcatttt gttggtatca aaggttcagg aatgagctcc ttggctcttg ttttacatga
    11281 acaaggtcta aatgtccaag gatcagacat tgaaaaatat ttctttacac aaagagattt
    11341 agaaaaagca aatatcacga ttctgccatt taacgcagat aatgtaaaac cagggatgac
    11401 gatcattgca ggaaatgcat ttcctgattc acatgaagaa atccagcgag caaaagaatt
    11461 aggtttggaa gtgattcgct atcacgactt tattggtcat tttatccaaa attatacgag
    11521 tatcgctgta acaggctctc acggaaaaac aagtacgact ggactgctct ctcatgtatt
    11581 gagtggtgtc cgtccaacaa gttatctaat tggagatgga acaggacatg gtgatccgca
    11641 agcggaattc ttttcatttg aggcctgtga atatcgccgt catttccttg cctattcacc
    11701 agactatgca atcatgacca atatcgattt tgatcatccg gattattata caagtatcga
    11761 cgatgtattt acagctttcc aaacaatggc tggacaagtg aaaaaagcta tttttgcgta
    11821 tggtgacgat gcttatttac gcaaattaaa agcaaatgtg ccgatttatt attatggtgt
    11881 cacagaaaac gatgatatcc aagcacgaaa catcgaacgc acaacttctg gttctgcttt
    11941 tgatgtctat catggggatg aatttgttgg gcacttcact gtaccagcat tcggtaaaca
    12001 caatatctta aatgctttag gtgttattgc agtagcttat ttcgaaaaac tggatctgaa
    12061 agaagttgca gaagaaatgc tgactttccc aggagtaaaa cgtcgattca gtgaaaagat
    12121 cgtagcagac atgaccgtag tcgatgatta tgcgcatcac cctgcagaga tcaaagcaac
    12181 gattgatggc gcacgccaaa aatatccaga taaagaaata attgcagttt tccaacccca
    12241 tacgtttacg cgtacgattg cattgatgga tgaatttgca gaagcacttg atttagctga
    12301 taaagtttac ttatgcgata tttttggttc ggctcgggaa gaacaaggaa acgttaagat
    12361 tgaagacctt ggagcgaaaa tcaaaaaagg tggagaagtc atcaaagaaa ataatgtatc
    12421 tccattgtta gattatcatg atgcagtagt aatcttcatg ggtgctggag atgttcaaaa
    12481 atttgaacaa gcgtatgaaa aacttttaag cagcacgacg aaaaatgtac tgtaatacaa
    12541 ttactgcagt gtccttataa aaatagaaag agggggagtg gcaaaaatct tgccaagccc
    12601 ccttttttgc aacttatgat aaacggtgtt caaaagcttg catctgcggt aataagccca
    12661 atcaaatcaa aaacatgaga agctgttttt tcttggctgt tcttattatt tgatgcagga
    12721 cagctttttc acgacctctg taaactatag gaatctgtta aatcaaggga gcagaacttg
    12781 ccttttacgc tacttttggt acaataatgt atgattaaaa ataaactgga gggtttctat
    12841 cttgaacata ggtaagccga gaaaactagg aaaaacaata aatgaaatcg aggaaggcga
    12901 ctcgttatcc ttaacagaat ctattgaaga taaccagctt ttgctgtatt tgggattgac
    12961 gaatgatgca aatcctttgt atatccaaca tgactttgca caaaaaacag aatatcaaca
    13021 gccaatcgtt ccatcagtga tgctgatggg gatcatcaca agtgcaattt caaagcatct
    13081 tcctggacca ggatcacatg ttgtcaattt ttctgtcaat tttattgaac cggttttcca
    13141 ttatgaaaca ctgacttttc agtttgaggt cataaaagta gataagatga aggatgtggt
    13201 gacgatttct gtagaagcgg agaatacgaa cgaagatcgt gtgttggatg ctgtcgttat
    13261 ggtccaaccg ccacaagttc ctgaattgga aatagcaatc gaaagtgaag gtgaattgaa
    13321 tgaataatcc aagtacatca atgtcaggta tcaatcgttt ttatgcaaaa gtttatggat
    13381 ttttaggtat gggacttgcc cttagtgcag tcacttctta cttggctctt tgggtatttc
    13441 ctttgcaatt agcaactttt atcaataatt ttccactagg ctttgtgggt ctgtggatcg
    13501 ttgaactgat tttagtaatg gttctaggcg taaaagcaca aaagaatccg agcttagcaa
    13561 tcggtggatt tattgcctac tctcttttga atggcataac attagcggtt actcttgcat
    13621 actacgatat tggaacagta acgcaagctt tcttgacagc tactttgatg ttcatgggga
    13681 tgtctgttgt cggagtaaca acaaaaagag atcttagcgg ggttggaaga gcaggacagg
    13741 cagctttaat cggagtgatc attgcactag tcttgaacat cttcattttg agaagtagcg
    13801 tagttgagct gttcatctcc ctactgttag tcgtcatctt tgcagggatt acagcttatg
    13861 ataaccaaag catccgtaat atctatgtcc agacaaacgg aacagcacat agtggaattg
    13921 ctgtattcat ggcattgaag ctgtatttgg actttatcaa cttgttcttg gcgtttctga
    13981 gaatctttgg acggaacaac taaaaaagaa aaaaattcat cagttggggc tataccgaat
    14041 tatttggtat ggtcccgctt tttcttttcg cattccgcag gattctttgt tagaatgaat
    14101 aagaacttta cagtaaggag ttaagaagat gacaaaaaat aaattattac tcgttgatgg
    14161 gaacagtgtg gcttttcgcg cattctttgc gcttcacaat tctcttgaac gtttcaaaaa
    14221 tagaaacggt cttcatacaa atgcaatcta tgcattcaat acgatgtttg aaaatgttat
    14281 gcaaaaagag caaccgactc atgttctggt tgcgttcgat gcaggaaaaa cgacttttcg
    14341 gacagaaatg tatgcggagt acaaaggtgg aagatccaaa acacctggcg aattcaaaga
    14401 acaaatgcca tatatacgtg atttgttgac aggactaggg gtacagtatt acgaattgcc
    14461 caattatgaa gcagatgata ttatcggtac tttggcagaa aaagtagaca aagatcaatt
    14521 tgatgtcgtc gtgctttcag gtgatcggga tttgactcaa ttagctagta aagaagtaaa
    14581 agtggatatc actgtaaaag gtgtcagcga tatcgaaagc tatacaccag aacatgtagc
    14641 ggaaaaatat gatgggttga cgccaaaaca gattattgac atgaagggac tagccggaga
    14701 tgcctctgac aatatccccg gtgtgactaa aatcggtgaa aaaacagcta tcaagctatt
    14761 gaaacaatat ggctcagtcg aaggaattta tgaacatatc gatgaaatga agcaaagcaa
    14821 aatgaaagaa aatctgataa atgacaaaga gcaggctttc ttatcgaaaa aattggcgac
    14881 catcaatact tcagcgcctg tggatgtctc tatcgactca ttgaagtatg aagggaaaaa
    14941 tctcgataaa ctcgttccgt tttataaaga aatggatttc aatcagttcc tttctaaatt
    15001 gaatatcgta gaagaagaag taaaaatgga tgatattttg tttgaagtcg ttcatgaatt
    15061 caaagaggaa atgtttacta cggatatggc gttgtacgtg gaaatgatgg gcgacaatta
    15121 tcatacagag gaaatcgtcg gagtagcgtg ggggacagaa aagaaaattt atgtcacgaa
    15181 cgatctatct gtattcgaaa accgagcgtt ccattcttgg atcactgatc cgactcggct
    15241 gaaaaaagta tatgatgcga aacgaactta tgttgcttta aaccgctata ctggaaaaac
    15301 gaaaggaatc gattttgatg tcttgctagg tgcatacctt ctcgatacga atgaaaaaag
    15361 cacagatatc gaaggaatag ctgctcatta cggatacaac gatatccaat cagatgaagc
    15421 tgtatacggc aaaggggcga aaaaaggttt accagaagaa gaggaactct tttttgctca
    15481 tttagcgcga aaagtagctg caatcaatgc gttgacacca aaattgagcc aagaactggc
    15541 agaaaaaaac caagaagatc ttttccggaa aatggaactg ccattgtcta tcattttggc
    15601 agagatggaa ataagcggga tcaaagtaga tgcgactcgc ttacaagaaa tgaagggcga
    15661 gttctctgct cgcttaagag agatcgaaca aaaaatctac gaagaagccg gcgaagaatt
    15721 caatttgaat tcaccaaagc aattaggagt gatcttattt gaaaaaatgg gattacccgt
    15781 tatcaaaaaa acaaaaactg gatattccac agccgtagat gtactggaac agcttcgtga
    15841 acaagcacca atcgtagagg atatcctcac ctatcgtcaa attgcaaaaa ttcaatctac
    15901 ctatgtcgag ggactgctga aagtgatcca atcagatgga aaagtgcata cccgttatgt
    15961 ccagacattg acccaaacag gacgattaag ctctgttgat cctaatttgc agaacatccc
    16021 gattcgatta gatgaaggga gaaagatacg tcaggcattt gttcctagag aaaaagactg
    16081 gctgatttat tcttctgact attcacaaat cgagttacgc gtacttgcgc atatctcaaa
    16141 tgatgaacat ttgaaagctg ccttcctaga aggtcaagat atccatgcca gcacagcgat
    16201 gcgtgtattt ggaatcgaaa aggcagagga tgtcacacca aatatgcgta ggcaggcaaa
    16261 agcagtgaat tttggtatcg tgtatggcat ctctgattac ggactttcac aaaatctagg
    16321 aatcagccga aaagcagcac agcaatacat cgatacgtac tttgaaaaat acccaggtgt
    16381 caaagaatat atggaaagaa tcgtacgcga agcaaaagac caaggctacg tcgaaacgct
    16441 gtatcaccgc cgtcgatatc tgccagacat caattcaaga aattacaata tccgttcttt
    16501 tgcggaacga acagctatca atacaccaat ccaaggaagt gctgctgata ttttgaaaat
    16561 cgcgatgatc gaattggata aacgattaaa agaaacaggt cttcaagcta cgatgctgtt
    16621 acaagttcat gatgaacttg tcttcgaggt accggaaaaa gaacttgaat cattagataa
    16681 attggtgaag gaagttatgg aacaagctgt ttctcttcat gtaccactga tcactgacag
    16741 cagttgggga aaaacgtggt acgaagcaaa ataaacattg tttaagacag agcaatataa
    16801 tgaaggtgaa aagaaaaaat gccagaatta ccagaagtag aaaccgttcg taaaggattg
    16861 gaacggttag tagtaggaaa aacgattcaa aaagttcagg tcttgtggcc caagatcatc
    16921 gagcaaccag agacacccat ctttgaggct tctcttgttg gcgaaaccat ccaatccatt
    16981 ggacgtagag ggaagttttt aatttttcat ctcgatcatt gtgaactgat ctcacacttg
    17041 cgaatggaag gaaaatatca atttacgaaa gaaaatacac caatcgataa acatacgcat
    17101 gtacttttct tttttgagga tggaagccaa cttcgctaca acgatgtacg aaaatttggt
    17161 cgtatgacaa tcgtcgaaaa aggagcaagt gcaacttacc gaggaatcat gaaattggga
    17221 cctgagcctt tgccagatag cttcttatta gcagatttcg caaatggact gaaaaagtcc
    17281 cacaaagcaa tcaagccatt gctgctagac caacgtctag tgactggtct aggtaatatt
    17341 tatgtagatg aagcattatg ggaagcgaag atccatccag aacaaccggc gaacacactg
    17401 cgccccaaag aggtagaaca attacgtcta tcgatcattg atgttttgga tcgtgcaata
    17461 gaagccggag gtaccacgat tcgcagttat ttgaatgcat taggagaatc aggcggattt
    17521 caagtagcac tgcatgtcta tcagcaaact ggcaaaccat gtatacgttg tggaacgccg
    17581 atcgtgaaaa caaaagtggc acaaaggggg acgcactatt gtccgaattg tcaaaggcta
    17641 aaaatcgcaa agtaggattt gttttaggtt tgacgggtgg aatagctacc ggtaaaagta
    17701 cggcagccaa agtctttcag tctcatggat ttcctttgat cgatggcgat gtgattgcca
    17761 gagaaactgt tgagcctgga acgcttgctc tgaggaaaat tgtatcagtg tttggccaag
    17821 aggtattgca gcctgatggg caactagatc gagggaaact tgggatgatt gtttttccat
    17881 caaaggaaaa acggcaaaaa cttgatcagc tattagatcc gtttatccga aaagcgataa
    17941 aagatcaaat cgcctctcta agttccaatc atcctttagt aattgtagat atcccattgc
    18001 tctacgaagg tcattatgac cactatatgg atgcagtagc tgtcgtttat actacgccag
    18061 aaactcagct tcagcgtttg atgaaacgta atcaactgac gctagaacaa gcgcagcaga
    18121 gaattagtag tcaacttcca atcgaagaaa aaaagcagcg tgcggatatt ttgttcgaca
    18181 acaatggaac aaaagaaaaa cttgtgggac aaatcgaaaa ttggcttttt gctaatcgct
    18241 ttctttgagt atctgtgtca attttgctat cctgagtata tagaaagtga gggatagcga
    18301 tgggatcatt aaaaaatcaa aaggataaag tcgtaggtaa cgcaaaagaa aaaatcggcg
    18361 agatgctcaa taaagaaaat ctaatcgatg aaggtcgtac gcaatcagaa acagcagaag
    18421 aaaaagaaaa gcagtaccaa gcaagaatcg atgaaataga agaccagcag gcagaagaag
    18481 aagcgaagcg gcaagatttg actcaagaac gaaaaaatcc gacacctgat cgtagtaaaa
    18541 caccgctccc agaaagtgac cacattcccg atgagcaaaa aatcgaggaa cagcgaatga
    18601 aacactatac aggaatcgaa gagaagttat aaaatagtaa aaaatcgaga tgtgacttga
    18661 agcagatgag aaggtgttca tctgcttcaa gttttttgtg ctagatgact aaatcagctt
    18721 ttgtgtaagt tatttctcag taatcaaggt gatcagtatt ggaaaattga aatttagtaa
    18781 ggacagggga cacaattacg catgaaagta gaaaaaattg ttcttatatc cgtgtttttt
    18841 gggtaggaca gtcgcgtttg tgatttgttt cgtgttataa tacaactagt tgtaaagaaa
    18901 gacacatcct ttatataaaa tgcgatgcaa gaggtgagac aaaatgagat gtcccagatg
    18961 tcaacataat aattcacgag taatcgacag ccgtcaagca gatgatggac gtgcgatccg
    19021 tcgccgtcgc gaatgtgaga attgttcgtt ccgattcact acatttgaac gaattgaagc
    19081 tgctccgtta ttagtaatca agaaaaacgg ggaacgcgaa gagttcaatc gcgataaaat
    19141 tttaagagga ctcatccgtt cagcagaaaa aagacctgta gctatggaac aaatggaaca
    19201 aatcgtcaac catgtcgaaa accgcgtacg cagtctcgga gaaaacgaag tatcgacgaa
    19261 tctaattggt gaatatgtga tggaagattt agttgattta gacgaaatcg cttatattcg
    19321 ttttgcaagt gtttatcgcc agttcaaaga tatgtctgtt ttcttaaaag agttgcaaga
    19381 tatcgtggat aaagcaaaag aaaataataa agagaataat aaagaaaaca attaagaaac
    19441 aaaaaggagg catttccttg gaaaatgctt ggaaagagct tcaaccaaaa aatatttacc
    19501 aaggaagaaa agcggctccg ctgagagaag acagcaagaa cgccttgctg tatctttatc
    19561 agccactaat cggcggagaa gccttgagta tctatttcac cctgttatca gaaatctctc
    19621 aagaatctgg caaaggtcct gaagggatgc atgcagatct gcttagtagt ctaggctgcg
    19681 gtatcccgca attttatgat gcaagaaaaa agctagaagg aatcggctta ctggatgttt
    19741 attttaaaga agatagtgat ctgggacctc gttttattta tgagctgtta gaaccactca
    19801 ttcctaaagc atttttcaaa gactctgttc tggcttttct tcttctggaa aaagttggtg
    19861 aacgacgatt ccagaagctt acccaattct ttgaacctaa aaggcataca gcagagggat
    19921 atcaaaaaat cacaaaaaaa tttttagatg tttatcgctt caatgaagca gtgtacgctg
    19981 ctaatcaaga aaacatcgaa tcgctgaata aatcttttga agaatctgaa tcagtagcat
    20041 tacttgaagc agattcgaca ttcgattggc agtttttgaa tgattggctg gcaaaaaaac
    20101 atattgcaag tcttgatgat ccaatcatca aacaagtcga catgtatcat cagctttacg
    20161 gtttcgatga attgacactt ggcgaactga tcagtcaatc ttatgacttt agtgaacaaa
    20221 aagtatctga aaaagaactg caaaaagcca ttttggcaat gcagagacgt ccggtgaagc
    20281 aaacaaaaga aacagttgcg gtttctgaaa acagtaatga accctcgtca aacgaacatt
    20341 tgacaaacgc agcgcttcag ctgataaaag aagcacagag cattccaccg atgaaatatc
    20401 tggaagcaat caagtcagaa aaaggcggat atgtttctaa acaagaaaac tggttactgc
    20461 aagatcttgt ttctcaatca ggtctttcca gtagcgtgat caatgttttg ctgaattatg
    20521 tactagtgat caagaataat gctagcttaa atgccagtta tgtaaataca gtggcaaatg
    20581 aatgggcaca aaagaaaatc gccacagcag aagaagcgat ccagcacatt cggcaaataa
    20641 gtaatcaagc aaaacaatca aaacaaaaga agcaaacaaa ttatcaaact ggcaagcgaa
    20701 atgttcgacg ggaaaagctt cctgattggg tcaaccagcc aaaagatgaa aaacagatca
    20761 gcagcgagaa aaaagcagag attgaccgcc gttttaaaga atacctggca aaaaaggagg
    20821 gtgatatcta gtggaagacg taggcaaaga attgaagagg atcatcagca aacgcaatta
    20881 tcaagaaaag tatgctgaaa tgatcgctga agtcttaaat gatgcggatg ttcaagcttt
    20941 tctaagcgca caccaagaag aattgacaca agcggatatt gaaaaaagtt acgctaaatt
    21001 gtatgaattc gtgcaagaaa agcgtaaata tcaaaaaaac gatccaacga tgatcgctcc
    21061 cggctatgag ccgaagctga cgttgaattt tcattatgtg gatgtcactt atgtaccaac
    21121 ggaagcattg ttagcacggc aaagacaaga agaaatcaga agccgagtaa aagcaatgga
    21181 tatgccaaaa gatattcaat cggcttcttt tgaaaacttt gaacgtacag atggacgagg
    21241 atatgcgagc ttagaagccc tagattttgt agagaaatat actgctgatc caaaagggta
    21301 tcataaagga ctgtatctag taggaagttt tggtattgga aaaacatatt tattaggagc
    21361 aacagcgaga gaattagcga ttgctggatt caccacgacg ctagtccatt ttccgacatt
    21421 tgccgttgag atgaaacagg caatcggaaa agatcaagtg gcagaaaagt tagatgcagt
    21481 gaaacgttca cctattttga tgatcgatga cattggtgca gatgcgatga gtagttggat
    21541 acgagacgaa gtattcggtg ttatccttca atatcggatg caggaacagt taccaacctt
    21601 cttctcatcg aattttacaa tggatgaatt ggaacagcat ttgtccgtca ctcaacgtgg
    21661 agatgaagag ccgctaaaag cgaaacggat aatggaacgc atacgttatt tgacaaaaga
    21721 aatcgaaatg actggtcgca accgacgcaa tggttgaaca gttgacaagt ccaactgaca
    21781 tttgacctag tagtaaaagc aggtcagcga atcattatat ggacagaaat gaccggagac
    21841 aatcaccgca acaagtaatg cagaaactta aacggaggat tttttatgag ggctattttt
    21901 tctagtatat ctgtagttgg tctatttttt cttttagcag gctgcggtag cgcagatagc
    21961 aacacaggtt ctgttgattc gattgatgcg ggtcaaacag taaaaacaag cagtacgaaa
    22021 acggagagac aaagcatatt tgtcggaacg attgaaagta tcactcaagt agaagcagaa
    22081 gaagaaacgc ttcagttgaa actcgtcgat gtcatggcca aagaagatcc agcgaatatg
    22141 ggaacgtcat tcagcaatga cggagtgatc ttaaatgcta ctgctgaaaa aataagcgtg
    22201 gacataaat
//
LOCUS       DAXQKX010000046        22154 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.047, whole genome shotgun sequence.
ACCESSION   DAXQKX010000046 DAXQKX010000000
VERSION     DAXQKX010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22154
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.047"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(61..648)
                     /locus_tag="ACF3MF_001905"
     CDS             complement(61..648)
                     /locus_tag="ACF3MF_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927886.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            823..2145
                     /locus_tag="ACF3MF_001906"
     CDS             823..2145
                     /locus_tag="ACF3MF_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFE3927887.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIETGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            2300..3076
                     /locus_tag="ACF3MF_001907"
     CDS             2300..3076
                     /locus_tag="ACF3MF_001907"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFE3927888.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            3069..3638
                     /gene="rnmV"
                     /locus_tag="ACF3MF_001908"
     CDS             3069..3638
                     /gene="rnmV"
                     /locus_tag="ACF3MF_001908"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HFE3927889.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            3631..4515
                     /gene="rsmA"
                     /locus_tag="ACF3MF_001909"
     CDS             3631..4515
                     /gene="rsmA"
                     /locus_tag="ACF3MF_001909"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HFE3927890.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            4966..5595
                     /locus_tag="ACF3MF_001910"
     CDS             4966..5595
                     /locus_tag="ACF3MF_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927891.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(5719..6828)
                     /locus_tag="ACF3MF_001911"
     CDS             complement(5719..6828)
                     /locus_tag="ACF3MF_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3927892.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            7037..7459
                     /gene="mgsA"
                     /locus_tag="ACF3MF_001912"
     CDS             7037..7459
                     /gene="mgsA"
                     /locus_tag="ACF3MF_001912"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008929 - methylglyoxal synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006007 - glucose catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019242 - methylglyoxal biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HFE3927893.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     regulatory      7646..7744
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01831"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="THF riboswitches regulate genes encoding folate
                     transporters and folate metabolism; They are most commonly
                     found in Clostridiales and Lactobacillales; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="tetrahydrofolate"
                     /db_xref="RFAM:RF01831"
     gene            7782..8318
                     /locus_tag="ACF3MF_001913"
     CDS             7782..8318
                     /locus_tag="ACF3MF_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HFE3927894.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(8358..10121)
                     /locus_tag="ACF3MF_001914"
     CDS             complement(8358..10121)
                     /locus_tag="ACF3MF_001914"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3927895.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(10124..11839)
                     /locus_tag="ACF3MF_001915"
     CDS             complement(10124..11839)
                     /locus_tag="ACF3MF_001915"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3927896.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(12618..12842)
                     /locus_tag="ACF3MF_001916"
     CDS             complement(12618..12842)
                     /locus_tag="ACF3MF_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927897.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            13033..15810
                     /locus_tag="ACF3MF_001917"
     CDS             13033..15810
                     /locus_tag="ACF3MF_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFE3927898.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            15891..16310
                     /locus_tag="ACF3MF_001918"
     CDS             15891..16310
                     /locus_tag="ACF3MF_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFE3927899.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            16322..16792
                     /locus_tag="ACF3MF_001919"
     CDS             16322..16792
                     /locus_tag="ACF3MF_001919"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFE3927900.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            16809..17588
                     /locus_tag="ACF3MF_001920"
     CDS             16809..17588
                     /locus_tag="ACF3MF_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFE3927901.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            17575..18396
                     /locus_tag="ACF3MF_001921"
     CDS             17575..18396
                     /locus_tag="ACF3MF_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFE3927902.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            18413..19462
                     /locus_tag="ACF3MF_001922"
     CDS             18413..19462
                     /locus_tag="ACF3MF_001922"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFE3927903.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            19475..20479
                     /locus_tag="ACF3MF_001923"
     CDS             19475..20479
                     /locus_tag="ACF3MF_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFE3927904.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            21112..22131
                     /locus_tag="ACF3MF_001924"
     CDS             21112..22131
                     /locus_tag="ACF3MF_001924"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFE3927905.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
BASE COUNT         7157 a         3887 c         4556 g         6554 t
ORIGIN      
        1 aaaaaaacaa tcatcggctt tgacttcgat gattgttttc tttattttgt aaaaatccta
       61 tcacttgatt ttatggtaac cttttatttt tgtcttcaaa cggcttggta agagagcagt
      121 aagcagtgca aatgggatcg aaaagacata ccagaaaatc gtacgtccga taccataatg
      181 ttgatagagc tttgtcaaca tcacgtgtaa caagatcaac cctaaaagca aggagccagc
      241 tataaaccaa tgattatccc aatgcatgac ttcactaagt gccatcactc caaaaggata
      301 gaaataaaaa tagatcccga ctaaggtcat ccgccagttc tttgtaaatg ttccgatatt
      361 caataaaaag aaaatcgctg aaagcaaaat accgataggc ggaaaaagcc caaccaaaaa
      421 ggaatacaac atcccccaca agatcatcac aggacctttg atcaatgcaa cgattgcgat
      481 gaacaaagtc agcaatatta gtttttgtga taacgttgca acagtcatta atccaaataa
      541 aattaatgtg aaccaatgcc aatgggactg ctgttgttct ttacgggaaa aatcgacccg
      601 gttggataaa taatctgcta atttcggata agaacgctta aaatccataa actgttcctc
      661 cttcgtggaa aaggtaggtt tagtatacga aaaataaaaa agaaatacat ccgtcttaag
      721 agggagtttt tcactgaaag tggagaaaaa agaatggtaa attaaaatat tctcagttat
      781 actgaaaatt ataccaaatt tcaaagaaga aagaggatgg gaatgaaagg caaactaaaa
      841 cgagaaatca atctgtttgg cgcattagct accgttatgg gaaccgtgat cggtgcaggc
      901 gtcttcttca aaactgctgc tgttactgct agtactcagt ctacaagttt gacattgcta
      961 gcttggcttt tgggtggttt cttaacgatc tgtgctggat tgacagtggc tgaattagct
     1021 acagcaatcc cggaaactgg tggagctgta aaatatattg aagctgcgta tggaaaattg
     1081 cccagctttt tattaggatg ggcgcaaagc ttgatttact ttcctgctaa tattgctgca
     1141 ttatcgatta tctttgcgac acaattgacg aacttattac aattatctac cgattatctt
     1201 ttgttgattg cagtgatcac cgctgtttct gtgacagggt tgaatttgtt agggacaaaa
     1261 gtcggtgctt ctgtacaatc agtgacgttg attgttaaat taataccaat tgctgtgatt
     1321 gtcatatggg gattattgac cccaggacaa ggaactgtcc agttatttcc aatcgaaact
     1381 ggaaaagatg ttacttttgt cgaaggattg agcagtgcgt tgttagcaac gttgtttgct
     1441 tatgacggct ggttaggtgt cggtgcaatg gcaggggaaa tgaaacggcc ggaaaaagat
     1501 ttgcctaaag caattattct tggtttgagt tttgtaacag tcgtttatct attgatcaat
     1561 tttgtttttt tgaaaacttt gccgattgat catcttgccg gtaatttgaa tgcagcttct
     1621 gaagcatcag acgtcatttt tggaggaatc ggtggaaagc tggtcactat tgggatcttg
     1681 atctcggtat acggtgcatt gaacggttat acactaactg ggatccgcgt gccttatgcg
     1741 atggctttag aagacgagct acctttcagt aaacagctga caaagctttc aaagaagttt
     1801 acggttcctt atgttcctgc ggttttccag ttagcagtag cttgtattat gatgagcctt
     1861 ggttctttcg actttttaac agacatgttg atttttgtga tgtggctatt cagtttactg
     1921 atttttatcg gtgtctttat tttaagaaaa aaagcgccgg aattgccacg tccatataaa
     1981 gtaccacttt atccaatcgt tccgattatt gcgattctcg gtgctatttt cattttaggt
     2041 atgacgatga tgacgcaaac gaaattagca ttgatcggta taggtgttac cttgataggt
     2101 atcccagtct attatcaaaa aaagaaaaaa cgctcagaag agtaaaatat ttcaacaaca
     2161 gacagaaaaa gtacgaacta ggtcctctag atcttcgtgc tttttctatt tcaataaaac
     2221 aagttcttct attttgattt ttgctacttc tgcaagtagt gcttatgtgc taaagtaaga
     2281 atgaaaagga gagataaaca tgatatttga ttctcatacc catttaaatg ctgaacagtt
     2341 caatgaggat attccagaaa cgattcagcg agcacaagaa atgggggtaa cgaaaatggc
     2401 ggtcgtgggc ttcgatacgc caacgattga aaagtctttg caattaagcc atgactatcc
     2461 aaatatatac agtattatcg gctggcatcc gacagaggct ggcagttata cgaaagaaat
     2521 cgaaaataaa ttacaagaac aattgacttt accaaaggtt gtagcattag gggaaattgg
     2581 cttggattat cattggatgg aagacccgaa agaagtccaa gataaagtat ttcgcagaca
     2641 gattgctatc gcaaaagaaa tgaacctacc aatcagtatt catactagag aagcacttga
     2701 agacacgtat caaatcctaa aagaagaaga tgttcgagat atcggtggaa tcatgcatag
     2761 tttcagtggt gattatgaat gggcaaaacg atttcttgac ttagggatgc atatttcatt
     2821 tagcggtgtc gtcactttca aaaaagcatt agacgtccaa gaggctgcag caaatgtacc
     2881 aatcgaacga ttacttgtgg aaacagatgc cccttatctg gcaccagttc cttttagagg
     2941 aaagcgaaat gaaccaggct atactcgtta tacagtagaa aagattgctg aacttcggaa
     3001 tcttccgaca gaagaagtgg ctgcccaaac atggacaaat gcgcaccgat tatttggtct
     3061 aagcgaacat ggataagatg aagatccaag agattatagt cgttgaagga aaagacgata
     3121 caagaaggct gcgggaagta gttgatgcag atacgataga aacaataggg tctgcaatca
     3181 atgaagagat cctgatgcaa attgaacatg cccaagagac tcgtggagtg atcgttttta
     3241 ccgatcctga tttttcagga gaaaaaataa gaaaaatcat tatggaagct gttcctcagg
     3301 caaaacatgc ttttttgccg cgcacacaag ctaaaccaaa gaaaaaggga agccttggtg
     3361 tcgagcatgc aagtgatgct gctattttag aagcattgaa aaaggtcgtg acgccagaca
     3421 tttcccaaac ggctgtttct gaaatcacta gacaagacct tttagactat ggtttaatag
     3481 ctggggcaca agcaaaagaa aaacgagaaa aactaggtga cgagttgcgc atcggttaca
     3541 cgaacggcaa acaattggaa aaacgtttga agatgtttcg tattacgccg aaagaactcg
     3601 cccaagcaat gaaaatagtg gaggaacaac atgagtgaat atcgtgaaat tgcgacaccc
     3661 tctagaacaa aagagatttt attgaaacat ggtttttcat ttaaaaaaag tttaggacaa
     3721 aattttctga ctgaaccaaa tattttaagg aaaatcgtag aaactgcgca aatagatgaa
     3781 catacgaacg tgatcgaagt tggaccagga atcggtgcat tgacggaaca attagccaag
     3841 catgcaaaac aagtcgtagc atttgagatc gatgatcgtt tgatccctgt attggctgat
     3901 acgatgcaac cctatgacaa tgtgactatt gtacatcaag atattttaaa gaccgatttg
     3961 tcaacagctg ttagagaaac atttcatgag gagcttccgt taaaagtcgt agcgaattta
     4021 ccttactata ttacgacacc gatcatgatg cattttcttg aatcagattt ggttgtggat
     4081 gaactagtcg tcatgatgca aaaagaagta gctgatcgta tctctgctga accaggaacg
     4141 aaagcttatg gttcattatc gattgctgtt caatattata tggaagccag tttagcattc
     4201 atcgtaccaa aaacagtatt tgtccctcag ccaaatgtag attcagcgat tttgaaactg
     4261 acaagaagag atataccggc agtcgaagtg acagacgaaa aagcattttt ccgattgaca
     4321 aaagcggcat ttcagcaaag aagaaaaacg ctttggaata acttgcagca ttcgtatggc
     4381 aaagatgacc agacaaaagc atggttagca aaaagcttgg aaacagctgg aatcgatcca
     4441 aaacgtcgtg gggagacttt gtcattacaa gaattcgccg cattaagcaa tgcgatgtca
     4501 gaaaatatgc agtaaaaaaa gaggttgtga cagaagttgt gaaaaagctg tcctgcatca
     4561 agtaataaga acagccaaac aaaaatagtt cctcatgttt ttcgtttgtt tgggcttatt
     4621 accgcagatg caagcttttg aacaccgttt aagaaagagg ttgtgggcct gccgtttaac
     4681 tctaagtcac aaggaacaat ttcaaaaaac agcttctcat gtttttgagt tagttggtct
     4741 tattacttga tgcaagcttt tgaccactat tatgccgaac aaggagatgt gacacaaatt
     4801 ttgtcacatc tcctattttt gtttcttgat caaaaaattc ttatacttga tactcacact
     4861 cattttgtat ggatttagaa aagaatatgt gtcttgacag ttattagtaa gtgagttata
     4921 ctaagtcgac atttatgtgt caagacatat taggagagag aaaaaatgag aaaaaattca
     4981 gttcgaaaac taacgatttc tgctttattg attgggatgg gggtcattat cccaatggtc
     5041 atgcctaaaa tcatgattcc accagcttcc tttactttgg cgtctcatgt gccattattt
     5101 attgcgatgt tttttacacc aggagttgca gtggctgttg cgctaggtac gacatttggt
     5161 ttctttttaa caacgccggt tatcatcgca ttgcgagcat tgtcacatct tgtgtttgcg
     5221 ttgattgggg cttggtactt gcaaaagcat ccgagtatcg ttttaaaaaa tggacagttt
     5281 acttttgcta attggcgttt ccaagggttc aattttgtga tcggtgtgat tcattcttta
     5341 gcagaaatgc tagtagtcag catcttttac tttattggta atatgcctga aacatattat
     5401 tctcaaggat atttttatac agtattcatc ttgatgggga ttggtgggct tatccacagt
     5461 ttagttgatt ataatattgc ttattttata gcaggaacac tcagcaaata ttttgatatc
     5521 cccgtattta cggcagcaaa aaaagaaaat cggaaagagt cgattcaagg gtacgcgaag
     5581 aaaacgacat attagacatg atctctcaaa aaaaaaactc tcatctagta atggataata
     5641 aatcctctaa gatgagagtt ttttgtccta aaaagagctg caccaacatc ttctggcaca
     5701 gctctaacag ggggcaattt atggaagttt gatgacttgt tctgtttctt tatcaaagaa
     5761 gtggcctttg ctgatgttga aggcaaggtc gactatttcg cctggtttat ggaaatctct
     5821 tgcatctact tttgagatga actcagtaga accagttttt gtgtaaagca tcgtttcagc
     5881 tccaagtaat tcggaaacga caacttctga tttcactacg gcttcaggtg aagcttcaag
     5941 ggctacttgt tcactgtgga tgtcttctgg acgaataccg aagataactt cttttccttc
     6001 ataacctttt tcaactaata ctttgttttt tccttcagga atacgaagct taagcccatg
     6061 tccatctgtg ataacaccat ttttcaatgt cacattaaag aagttcatgg caggagatcc
     6121 aataaagccg gcaacgaaca tattgacggg tgtatcataa acttctttcg gtgtaccgat
     6181 ttgttggata aatccgtctt tcatgataac gattcggtca gccatagtca ttgcttctgt
     6241 ctgatcgtga gtaacataga tggtcgttgt ttcaagacgc tggtgaagtt tggcaatctc
     6301 agcacgcatg gctacacgta atttagcatc taaatttgat aatggctcat ccattaagaa
     6361 gacttttgca tcccgaacga ttgcccgtcc caatgccaca cgttggcgtt gtccaccaga
     6421 taaagcagct ggttttcgtt tcaagtattc tgtcagacct aagatctctg ctgcattgtc
     6481 cacacgtttt ttgatgtctg ctttatcata tttacgtaat ttcaagccaa aagccatatt
     6541 atcaaaaaca gtcatatgag gatacaatgc gtagttttgg aaaaccatgg caatatcacg
     6601 gtctttaggt gccacgtcat tcatgacttt tccgccgata tttagttctc cttcagagat
     6661 atcttccagt cccgcgatca ttcgcaaagt agttgacttt ccacaaccgg aaggaccaac
     6721 aaaaacgata aattcacggt ctttgattga tagattaaaa tcagttacag aataattttc
     6781 tgcattgtca tattttttat atacgttttt cagagccatt tctaccataa tacgttccac
     6841 actttctttt ttagttttat taactattta aagtataaat gaaagcgtta actaacttca
     6901 atgtcatgtt gaacaagaat tttttctttt ttttgtcaat gtgctagttt taagctttaa
     6961 taaatatcca taagaaataa aaactgatac actggagtaa ataagtatgt taacaatatc
     7021 aaaaggagtg tctcttatga aaatcgcttt gatcgctcat gaccgaaaaa aacctatgat
     7081 ggtgaaatta gcaacagcgt ataaaacaat attggaaaaa catgaacttt ttgctaccgg
     7141 gacgactggg cagaggatca cggaagcaac cggcttgccg atccatcggt ttaaatccgg
     7201 accgttaggc ggggatcagc aaattggagc catgatttcg gaggatcagt tagatttggt
     7261 gatttttctt cgagacccgc tggctgcaca gccccatgaa ccagatgtaa cagcacttat
     7321 ccgtttatct gatgtctatg agattccgtt agctacgaat atcggaacag ctgaggtgct
     7381 actaagagga ctggaagccg gcttcctaga ttttcgaaga atcgtccatg aaatagacaa
     7441 gcatccactt tcattttgat ggataagcgt atggaaaaat aacgtttaat gttcgcctat
     7501 atgtagctat aaaagctaaa caaactgata atatgcgata taatacgaac gtattggata
     7561 atataaacaa taatattagt ttttcgtatt tgcagtaaat gtgaaaatat gctatagttt
     7621 ctgtgggaaa agatcccaaa aataatacag agtagaaaat aaagcgttaa gtgctaagag
     7681 gatgggatgt tgcctcttgg acgaaggacg taatgttcgc ggttttattt tcgcattcgc
     7741 tgcatgatac gatgtagcag ctcttaaagg agatgctaaa aatgaagaaa caccggttag
     7801 acgcacgtat gattgctatt atgggcttat tgattgcatt gatggtcact ttgtcccgac
     7861 tggtagcaat cgagacccca tttattaaaa tcagtgtcac atttattcca caagtgatca
     7921 tgggcattct ttttggtcct ttttggtcag ggataggcgc agttttagct gatttagtag
     7981 gaatggccct cttctcgaaa tctgcattct ttattggatt tacattgaat gcatttattg
     8041 aaggagcaat ctacggattc tttttctatc gaaaagagat cacttggaaa aatgccattc
     8101 tggctacgct tagtgtcacg ctgatcatca acttattttt gacaccatta tggcttgcgt
     8161 tgatgtacca tgtgccattg ttcagctggg tcgtttgggc gccccgcctg ttaaaaacag
     8221 taatatggtt accgattcaa tcaattgcca tttattacgt aggacgtagt attccttaca
     8281 aaaaaatttt aagaagttta gcgatccacg ctaaataaaa aacaagcagt cttcccatcc
     8341 cagaagactg cttgttttta ttgtgctgtg aattgtgctt gatagagccg tcggtaataa
     8401 ccatcttttt gaagcagctc atcatgggtg cccatttcga caatagctcc ctgatccatc
     8461 actaatatct ggtccgcatt tttgattgtg gacaggcgat gggcaatcac aaaactggtt
     8521 tttccttcca tcattgctaa gaaggcttgt tggatttttt tctctgtcaa tgtatcgact
     8581 gagctggtag cttcatctaa gatcaacata gggggattac tgatcatcgt tcgagcaatc
     8641 gtcaacagtt ggcgttgtcc atctgatatc tttaaccctt gaccgccaat cttagtatct
     8701 aatttttccg gcaaacgttc tacaaattca tacatataag aggcttttag ggcatcattg
     8761 atttctgcgt cacttgcttc cggattccca aaacgaagat tttctcgcaa tgtactgtca
     8821 aatagccaag tatcttgtaa caccattcca aaacttttac gtaatgtatc acgttggata
     8881 gagcggatgt catggtcatc gactgtaatt gttccttttg ttgtgtcata aaaacgcatc
     8941 agcaaattaa caagtgtgga ttttccggcc cctgtttttc ctactatagc aatggtttga
     9001 cctggataag cagtaaaatt gaaatcttcg atcaaacgct gcttggggtc ataagaaaaa
     9061 gaaacatgat caaaagagac ttttcctttg atatttttgg gttccaaggc ataggcatct
     9121 ggcaaatcag gcttttcttc tggctgatcg atcaaatcaa atgctcgttc tagaccagaa
     9181 aaagcggttt gcagttgtgt cgtgattcca gaaagttcga taaatggttt agaaaactga
     9241 cttgagtaga tcgtaaagct ggaaatcaca ccaacagtga ttgacgaacc actcttcaat
     9301 gccaataggc cgccaactaa accaatcgat aaataagcaa ggtgatctac aaaacgagaa
     9361 gacgggtttg tcaaggaaga agaaaattgt gcccgttgtc ctttttcata tagatcagca
     9421 tttagcagtt caaattgctg ttgactagct tcttcttgct gaaaagcttt cacgattttc
     9481 tggttaccga ttcgttcggt cacaaagccc gagatatccc caataatcct ttgctgtcta
     9541 tcgaaatttg tttgtgaagc acgagcaacg atccaactca caaggaaaat aattggtgta
     9601 gaacaaagaa cgaccaatgt cagaagtgga cttagacgca tcataaaaat aaacgaaaga
     9661 atgatgattg ccactccaga aaataattga ttgaaggccg cagaaattgc aatggaaata
     9721 ttgtccatat catttgtaaa tcgactgacg atatttccgt gggagttttg atcataataa
     9781 cgaagtggca atcgattcag atgagcaaat gcatcttttc ttaattttgc aacggataag
     9841 taagctaacc gattgcttaa cacttggatg agccattgac tgactacgtt gattaaaacg
     9901 ataccaccga atagaataag taaatggaac agtcgattga agcggacctg tccttctcca
     9961 atcatttgat cgatactttg accaatttgt aacgtcatca caactgttgc aatcccattg
    10021 atgattccta gtatcacagc tagccaaatg tcttttgcat aggcagtaag gtaaggaatg
    10081 aatcggcgga gcgtctgcaa ggataatttt tttactttca taactattct tcctcctgtg
    10141 atgcgacgat ttcctgatat tctgctgatt gagcaagtaa ttcttcatgg gtaccctgag
    10201 cagcaatctt accttgatcc atcactaaga tatgatgtgc ttcttgaata gagcggacac
    10261 gttgggagat aataatcact gtactgccaa gataagtctg tagcgcctta cgcaaatcca
    10321 agtctgtttg ataatccaac gcacttaaag agtcatctaa aatcagtaat gctggcttgg
    10381 caatcaaagc tcttgcaatc gtcagtcgct gtttttgtcc gccagagaaa tttttcccat
    10441 tttccatgac ttttgtatct aaaccatttg gaagctgacg gacaaattct tctgcctgag
    10501 cgattttcag agcttcccaa cattcttttt ctgtggcgtc tttcttaccc cattgaaggt
    10561 tttcacgaat agtcccggta aatagtacag aagtttgggg aacaagagca atttgctgac
    10621 ggagatgatc cagctgccaa gaacgaacat ccattccgtc cattataact gtaccggaac
    10681 tgacatcata gaaacgcgga atcaattgtg tcaaagtcgt tttcccgctt ccggttggac
    10741 caatgattcc aaggactgta tttcgcttca gctgaaatgt aatattttgg agagaaagac
    10801 cagaatcagg agtataacgg aagtcaacat ggtcaaaagc gataattgct tcagaagaaa
    10861 aatcgggagt agtactgacc tcagcttcaa gaatcgaatt ttctgtgtct agcacctctt
    10921 tcacccgatt tcctgaagct tcggcacgtg tgaagatcac gacgaggttt gaaacaacga
    10981 tcagtgccaa aagcatttga ttcatataat tgatcaaagc aagaacttgt ccttgttgca
    11041 agctaccaat atttactttg atcccgccaa ctgtcagcaa acagatgatc ccgacattca
    11101 tgatcaaggt tgtagcaggt gataataggg cagagatatt ggaaacacgt aaataattgt
    11161 tcgctagatc atttgtgctt ttatcgaact tctctgtttc tttttttgtc tgcgcaaatg
    11221 cgcggatgac acgaacaccg ctaagattct gactaacgtg ttcattgagc tgatctagtt
    11281 tttcttgcac tttttggtag agaggaacgg tttttttgat gataaaaaat aaaatgattg
    11341 agaaaatagg caataatgct aagaaaaaca gacctacttc ccagtcgatc acaaaagcca
    11401 tgaccactga cccgatactt aaaaacggtg ctctgatcaa taaacgaatg accattgcta
    11461 aagctagctg aagctgattg atgtcgtttg tcattcgggt gatcaaggta tctgttccaa
    11521 aatgattcaa ctcgttgtga gagaaagtat tgattttttt gattagctga ttacgtaact
    11581 ctgtaccaaa tccttgtgaa gctactgaag catagtattg gcaaatgata gcacaaatca
    11641 gaccaatcac agacatagcg accatccata agcccatttc aatgattttt cctcggtcat
    11701 tcatttttag tccattatcg atcaaggaag ccatcattaa aggcaggaca agttcgaaga
    11761 cagcttcaag aaatttgaag aacgggccca aaatgatttg cttacgatag tcttttgcat
    11821 aacgtaataa ctgaatcata tgattcctcc tattatttat ttgtccacaa ttgaaaaaac
    11881 aagtactacc acattgtagc ttaggaaatt tagaatgaaa agagaacaag ccttttcata
    11941 aatgaaagtt ttattatgaa gaagctttag aaattgaata gactattttt tttaaaaaaa
    12001 agaaaatgag aaaacatgcc agtctcttca ttcataggaa cgtctatttt acttaatttt
    12061 tctataaatg aattctgcat aaaaaatata tcaagtaaat gtttatagat gaaactctat
    12121 ttacttcttt tttaatttgt tcttgcaatc ttttttgcta cgtaattttt gtaaaaaagt
    12181 gggttgagag aaatctaatt gattttcaaa gaaggagtat gaaaatgaga aaaatattta
    12241 ttcgtttatt gtgggtacta tcttagagga ataaataata gtggagaaaa ctatggtttg
    12301 gcgcagattc tatcaggttt gatggaacga agacaacctc ccgacatcaa gtcaaaagct
    12361 acttgagatt ttgatctgaa aataaaaaaa gaaaacaagg taggaacatc aatgtttcta
    12421 ccttgttttc gtaatcaatg ggaaaaaact aagagtggtg tacgtaatca ataaaaagga
    12481 tggtgacaac agtacctctt tactctctga aagcatcata actcgttttt cctcattatg
    12541 ccaataaatt gttgttatac cacatataag gatttgtaat agctaaaaac agacaggaaa
    12601 gttgaaatct gtgaatctta ttttgtatgg aaggatttat agaacgcaaa aatcaagata
    12661 aagatgaata aaaatcctgt ttcggctata tattgcgtat ctacgccaat aaaacgagtt
    12721 tgttctgtca tagccatata aagcaaaggc aaaaatacaa ctacagcgag ataagatccg
    12781 atgatttctc gaaaagtttt ccaggaagta tgtttcctgt ttttatattt atccgatttc
    12841 attgaatagt catagcctcc ttattctttc atatgttgaa attccagtat aaaaactgga
    12901 aggaactgta cgttttttag aataaaaatt ataagggata agtaggctgc tgtctataat
    12961 aagatatatt tttcaattct ttattaaaga ttttattgac aaaatgaatc cgttttctat
    13021 gatggaggag gggtgaataa gttgttgaag aaggaaattt tatgttactt agagaaccag
    13081 acagcctttt tcgatttaga acatatgaac gaggtcttta cagcacaaag gttagctgat
    13141 cattttgggg taaaaagaaa cacagtcagt cattatttga accagttaaa tgatgagcaa
    13201 ctactagtca aaatcaattc tcgaccagtg atttatttcc acaaagaagc ttttgaaaaa
    13261 caatttttta agttacgcac gaatttttat ttttctatcg atgatctcaa agaggaacag
    13321 ccttttttcg cgcaaccaaa agacttattc tcttttatga tcggatacga cgccagtttg
    13381 aaagaaagta tcgaacaaat caaaacagct ctttactatc cagatggcgg attaccactt
    13441 ttgattacag gcgaaagtgg cacaggtaaa agttatttag ttaatttggt ctatcagtat
    13501 tgtctgcttc atgatctgct agaagattct gcaccattca tcacttttaa ttgtgcacaa
    13561 tatgcagata atcctgaact tttgactagc aatttgtttg gacatgttaa gggagcgtac
    13621 actggtgcag aagaaaataa aaaaggggct tttgaagcag cagatggtgg gatcttgttt
    13681 ttagacgagg tacatcgctt aacaccagaa ggtcaggaaa aactgttcac ctatcttgat
    13741 caaggtgtga tttatcgtat gggagaacct aatttgtcac gccggatcaa aacacgtctc
    13801 ttttttgcta cgactgaaga gattactagt catttcttaa caactttcat tcgaagaata
    13861 cctatccgaa tcgaactacc tgcacttaat cagcgtagtc gtaatgaacg gctagaactg
    13921 atttactctt tttttctcga agaacaaaga aaaatgggga gccctttgtc agtcagtgga
    13981 ccagctttgt cacttttaac aagtcagaaa ttatccggaa acataggaga gctgaaaaat
    14041 atcgtcaaag tttcagcagc aaaagcatat gctgaacagc gtgaacagcc tgaaatccat
    14101 gtcacgatcc atcatttgca aaaagaacta cttgcgcagc ctattactaa aaatacagca
    14161 cagcaaggaa tctatattac gcaagaccag accttagagc aattaatgga gaagcaacag
    14221 cccgaacagc agcgaatcgt taaaagtttt gagcaaatcc taattgattt caagaaaaat
    14281 aactgtctgc tatattcttg cgaaggaaaa ttaaagcaag aagtgattca attatttgat
    14341 tttttgctgt ttgagaccag tagacaagaa aaacacgagc tgctggttta ttggacacaa
    14401 tctatccgag agacctttcg acaaatggaa actgcctatc aaatcaaatt cgatggaaac
    14461 agtgtctatg ccttgagtta ctatctctat cagcgaagca ctatcaaatg gttaccggaa
    14521 gaacatgata ttatccaact aatcaaagaa ttagaacaac aagtttctca gtcttatcca
    14581 tctagttatc actatgtcca acgaattctg gaattaagta agatcaaatt agatattgaa
    14641 gacacaagta tggatcggat tttactgacg atctatctaa aaaaagcgaa atggtcaaaa
    14701 gaaaaacgac tgccaaaagc gatgattgct gctcacggtt atgcaactgc tagcagtatg
    14761 gcaaatgtag taaatcgttt attacaagag gatctatttg aatcatttga tatgccacta
    14821 gatgtcacac cacagcagat tgcttcagaa atccttgatt attgcgaaaa cagcgatgtt
    14881 tcaaatggat tgatcatatt agtagacatg ggatctctga aagaaatcca tcagtttttt
    14941 aaaaaacagt tatccgtacc gcttttgatt ttgaataatg tgacgacacc tttagcaatc
    15001 acagtagggg aatgcctgca aaaaaatgta tcattagaag agatagcaga agagactgtt
    15061 cgacagatcc agccagaatg gcgactgctc tatccagagg aaaacaaacc caaagcactc
    15121 attactactt gcttcactgg aatcggtacg gcggtccact taagtgaact gctagaaaaa
    15181 agcttaccta cggcttgtca gttgaaaatc atcccatatg aatatcagca attaaaagat
    15241 aagaaaaaca gtgacccatt attttccata tacgaagtcg taggaatgat tggcaccaca
    15301 gatcctgata tcaccaatat cgactatctt tcattagaag acctcatctc gggggaaaag
    15361 atgtctgtac tagctgaatg gttggacact actatgaatg cttcagagaa ggaaatattc
    15421 aatcagcgca tcattcgtaa tttttcattg gaaaaagtac tggattccgt gactattcta
    15481 gatacagaga aggtgatggg agaaatcgat cattttatga gagaattaga ggtgcagttg
    15541 aatcgaagca tcagcaatcc caaaaaatta gcgttgtatg tccatgtgag ctgtctcatt
    15601 gaacgattga tccgacaaat gccaatcgaa acctatcaag gattagagaa atggaagcag
    15661 tgtcaaaaag aagggttatc tgctattaaa tctgcgttta gtgtcattga agagcattat
    15721 agtgtcatga tccccaattc tgagattgcc tatatctatg atattttgag tgaagataca
    15781 gagtttctct cgatagaaga agaattttga acataagcaa gttgttgcca ctaattttgg
    15841 catgcaactt gcttttttag tatgtgtaag tgaaaagagg agatgaaaaa gtggatagag
    15901 aaattatctt agcttcccat ggaaaatttg cttcagggat attagattca ttagagctga
    15961 tctatgggaa aaatcattct attactgtat tcgattgcta tactgatgag aattttgatt
    16021 tagcggaaac agtaaggcag ctttttatga ggtacaaaga taaagaaatc attgttctga
    16081 cggatctttt tggcggaagt gtcaacaacg aattcttaca atatatcaat cgggatcatg
    16141 tctatctcgt tgccggattg aatttgccac tattgattga gctagtatct cggttggacg
    16201 ctgaagtaga gacaactgtt ttgatccagc aggtgctaac tgattcaaaa aaaatgatcc
    16261 agttttgtaa cgagcggctc aatcagaaaa tagaagaaga cgaattttag gaggaagaaa
    16321 aatgattgta ttgacaagag tcgaccatcg gttattacac ggacaagtag ctttttcatg
    16381 gacacaaaca ataggcgcag actgtatttt gattgctaat gatgatgtac ctacgaatga
    16441 gatacgaaag acaacgatca aattagccaa gccacaagga gtcaaactag tgatcaaatc
    16501 aattgatgac tcgattgccg cgttgaaaag cggggtgaca gataaatata agttattcat
    16561 cgtagtggaa tcgatcgagg atgcatataa gctggcagaa gcgtatccag aaatcaaaac
    16621 catcaactta ggagggatca aggcaaaacc tggtactcgc agcatcggaa aagcggtaaa
    16681 tattttacca gaagaggagg aacgcttgaa acgattaatt gacaaacaaa tagaagtaga
    16741 aatccgtcaa gtaccagcag ataaaaaagt ggatgtaaga gaagttttgt aagaaaggaa
    16801 gaacctcaat gattgtacaa gcagtcttat taggaattgt tgcatttgtc gcacaatcag
    16861 aatatgcact agggacatcg ttgctttctc gtccgattgt gacggggctg tttacaggaa
    16921 tcgtgttagg tgatgtaaaa actgggatca ttatgggcgc aactttagag ttagcattta
    16981 tcggatcgtt ctcagtaggt gcttcgattc cacctgatgt tgtgaccggt gggattttag
    17041 ggacggcttt tgctattaca gctggagccg gtacagaaac cgcgctttta ctaggtttgc
    17101 cgattgctac gttgacattg atattgaaaa atatttactt agggcttttg attccaatta
    17161 tgaaccataa agcagacaat tatgcagaag aaggaaatta taaaggagtc gagcatatgc
    17221 acttgcttgc cggtatcggt ctttccttga tgcttggtgt tgtggtaatg gtttcttata
    17281 tggtgggaag caatacgatc ggaaatctat taaatatgat tcctgacttc gttcaaaagg
    17341 ggttgtcagt agctacaggg ttgattccag ctcttggttt tgcgatgctt gctcgtttgc
    17401 tgatcaacaa acaagttgca ccatattttt tcttaggttt tgctatagct tcttacttag
    17461 agattcctgt gaccggagta gctatttttg gtgcgatttt agcagttgtg gtagtcaata
    17521 ttatgaatgt ccgtcaacta ccacttcaaa caactgcagg ggaggtagaa gaagatgaag
    17581 aattctgaga tcaaaaacag caaaataacg aaaaaagagc taaatcacgt attttggcgt
    17641 tcttttcaaa tggagttttc ttggaattat gaacgtcaga tgaatatggc ttatgtttat
    17701 gcaatgattc cgattttgaa aaagttatat cagtcgaaag aagaaatggc agcagctttg
    17761 aaacggcatc tagagttttt taacacgacc ccacatatcg ttacactgat tttaggaatc
    17821 acggctgcaa tggaggaaga aaataaggat gatcctgaat ttgatgtgac tgcgatcgat
    17881 agtatcaaaa catctttgat gggacctctt gcagggttag gagattcttt cttttgggga
    17941 actttgcgat tgattgccac aggtgtgggt acctctttag ccatgcaagg aaatatttta
    18001 ggccctatct tgttcatttt gattttcaat attccgcaca ttctgtttcg ctatctagca
    18061 acaggttggg gatatcgctt aggaacgggt tttttgaaaa agatccaggc aaacggtatg
    18121 atggaaagtt tgacattagg cgcgtctatt attggactga tggtcgttgg agcaatgact
    18181 gccacgatga tcaccatcaa tattccttta aaaatcggtt caggagaaaa tgctgtgact
    18241 gttcaaagta tttttgatga tatcgttcca aatatcttat gtcttggagc atttggcata
    18301 gtgttttatc tattgaagaa agaagtgaaa ccattaacga tcttgatcgg actagctttc
    18361 tttggaattt ttggttcgtg gatagggatt ttttaaaaaa ggagcagaga aaatgtttac
    18421 gatgcaagat tatatctatg aagaaaagga agtactaagt acgatcttga aaaagaatga
    18481 tttttcgaca agagaacata tgaaaaaaac agtgaattta ctgatcttag caacgggttc
    18541 atcttataac gcttgtttag cagcgaagcc agcattggaa tcttatggtg atcttactgt
    18601 cgatattcaa gaaccttttt attttttcaa ttatggaaaa ctttctcctt caatcgatac
    18661 tgtgattgct gtgtcacaaa gcgggaaaag tgcttctact gttgaagcag taaaaatgat
    18721 acaaaaacaa gggttacctg ttgttgctat cacaaatgac gtgcaaagtc cacttgcttt
    18781 agaagctgca caaattattg atttaggtgc cggggtagaa tcagtaggct tcgttacaaa
    18841 aggctattct gcgactgttt tacagttact actcttaggg ataggaattg gaataagtaa
    18901 aaataaaatc agcaaaaaaa tagaacaaga ctacatgcaa cagttgcgca aaataatcaa
    18961 ccatttacca gcgattattc aaaaaacgga agaatttttt gatggatatc aaagtttatt
    19021 tcgtttagca cagcgtttcg tcaccattgg atatggtcca aactggggaa cagctaaaga
    19081 agcagagacg aaattgactg aaacaatccg cgttccgtca caaggatttg agttagaagc
    19141 ttatatgcac ggcccatacc tggaggcaga tgcttcgcat ttgctattct ttattgaagg
    19201 ggaaagtgta aataaggaac gttcgcaaaa gttgcaaaga tatatgagtc ggtacgttgg
    19261 agagactctc accattacca caaaaaaagc aagaaacgag aaaacacttg gattagcaat
    19321 agaatgtgat gaatatctgt ctgtattagc gcttgtcgtt ccgtttcaac tattcgctta
    19381 taaaaccgca gtagctaaag gtattgactt gaacaaaaag atttttgaag actttgatac
    19441 agtcttgaaa agtaaattat aagaggtgga aatcatgctg aaattcaatg aagaagaaca
    19501 aatcaaagca ataaaaggcg cactagcttt acgtccgcaa gtagaagaaa tcatcgataa
    19561 actttatgcg gaaaaatttg acgctgtcta ttatctagga atcggtggaa cgtatgcttc
    19621 ctcgatgcaa gctgtcactt atatgaatgg gaaaagcaac ttgcctgtct ttgtacagca
    19681 tgctgcagaa tattacacta ctggaaacaa aagattaaca aaagattcta tcgttatttt
    19741 gtcctctgtt accggtacaa ctcaagaagt agtgaaagca gtagaacaaa tcaagaaagt
    19801 aggagcgaca ctgattggat ttatcgataa agcgaacagt aagttgtctc agctatgcga
    19861 ttttgtggtc acttatccag ctcctggaac agaacaaatc aaatttttta tggcagcaga
    19921 tcgattgatg tatttgaatg gagaattcga agcttattca gaatactatg aacagctcga
    19981 acgttattta ccaacagggt tagtggaagc agagaaaaaa gcagatgcat ttggcttatc
    20041 atttgcagaa aaacatcgac gtgatagtat gcattatttt attggagcag ggaatcaatg
    20101 gggagctgtt tattcatatg ccatgtgtta ctgggaagaa caaagctggc ttccatcgaa
    20161 atctatccat gctgccgagt ttcttcacgg gacgttagag atcgtagaag aaacaacccc
    20221 agtcacatta tttttaggcg aagatgaaca gagagtgtta tctgaacgtg tggctaaact
    20281 tttgccaaaa atttgcagca attatacatt gatagacaca aaagactatc cagtagaagg
    20341 tatcagtgaa aaatatcgcg gacgtgtttt gtctttctta ttgatgcatg tagtgacaca
    20401 acgcatcgat gctcatgtgg agcagttgaa ctgccatcca ttagagatac gccgctacta
    20461 tcgtcagttt gattattagg atagactgga taaaaagaat ataaaaaata aagagagcag
    20521 cgataactgc tccctttatt tttttaaaat attggcatca attacgttat aaaacacatt
    20581 ttttgcatta tctacagttc aacttataat ctgtttaatg ggacatgtgg gtgccaacca
    20641 ttttttgtta tgcaatagta ctatttagtt gttgcatgga tccgtagtaa aagtccaagt
    20701 acaacgagtt gcgccagttt acatagcgtt ttgtatccag aatgttgact aaaacaaaag
    20761 ttcctatgtc aaccgtcaac agagacaatc tgtccgttgc aggacctgac agatttagaa
    20821 atgttcaatc tgtctcttat gtattttaaa tcaatactca ctaggagaag tttcctaacc
    20881 tcctaatagt aatgctggta gtaacattgt caaaactgct tcctcttagg aacaagcaaa
    20941 gcataacgag tgtaaaaata aaatgtagac tattgtaaca tatcattgat tatttcaagt
    21001 aaaaacgata aaagaagtaa acaaacactt aaaaacaatg gaaattagtc ccaactttaa
    21061 gaaatgtata ctataatgga aattatcaat tatttatttg gaggaatatc catgaaacaa
    21121 aaaatcgcag ttcttggtcc tggatcttgg ggcactgctt tagcacaaac attggcagaa
    21181 aacgggcatg atgtccgtat ttggggaaat gtacctgaac agattgatga aatcaataag
    21241 tatcatacaa atcagcattt tttacctgat ttgacgatcc cagaatcgat tatcggatat
    21301 aaagaattgg cagaagcagt ggataacgca gatgctattt tatttgttgt tccaacaaaa
    21361 gcgattcgtt cagtcgcaca ggaacttatt ggtaaaatga atactaagcc aatcattata
    21421 catgcaagta aaggactaga acaagatacg cataaacgaa tctcagaagt tttggctgaa
    21481 gaaattccag aagaaaaaag acaggcaatt gttgtattat ctggtcctag ccatgctgag
    21541 gaagtggcag tacatgatat cacaacaatt acagctgcaa gtattgatca aaaagcagca
    21601 gcctatgtac aaaaactgtt catgaatgat tatttcagga tttatacaaa taatgatgtg
    21661 attggcgtag aaactggtgc agcactgaaa aatatcattg caattggtgc cggcgctatc
    21721 catggattag gattcggaga tgatgcaaaa gcagcaatca tgactcgagg attggcagaa
    21781 atcagccgtc ttggtgtcgc gatgggtgcc aatcctctga catttatcgg tttgagtggt
    21841 gtgggggact tgatcgttac ttgtacaagt gttcattctc gcaattggcg tgccggtaac
    21901 ttgttaggac agggacataa gctggaagaa gttctagaaa acatgggaat ggtcgttgag
    21961 ggtgtggcaa cgacaaaagc agcagtagag ctagctcaac agctaggtgt tgagatgcca
    22021 attactcaaa caatctataa tgttttgtat aatggagaag atatcaaaaa agcagcaaaa
    22081 gaaatcatgt tacgtgacgg aaaaatggag aatgaatttt ctcttcgtta aatagatgat
    22141 caatagttaa tcgt
//
LOCUS       DAXQKX010000047        21381 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.048, whole genome shotgun sequence.
ACCESSION   DAXQKX010000047 DAXQKX010000000
VERSION     DAXQKX010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21381
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.048"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            6..305
                     /locus_tag="ACF3MF_001925"
     CDS             6..305
                     /locus_tag="ACF3MF_001925"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFE3927906.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="ACF3MF_001926"
     CDS             378..1739
                     /locus_tag="ACF3MF_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HFE3927907.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="ACF3MF_001927"
     CDS             1761..2021
                     /locus_tag="ACF3MF_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927908.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="ACF3MF_001928"
     CDS             2035..2787
                     /locus_tag="ACF3MF_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HFE3927909.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="ACF3MF_001929"
     CDS             complement(2881..3486)
                     /locus_tag="ACF3MF_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFE3927910.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="ACF3MF_001930"
     CDS             complement(3539..4513)
                     /locus_tag="ACF3MF_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HFE3927911.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5610)
                     /locus_tag="ACF3MF_001931"
     CDS             complement(4891..5610)
                     /locus_tag="ACF3MF_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFE3927912.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="ACF3MF_001932"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="ACF3MF_001932"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0019191 - cellobiose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFE3927913.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="ACF3MF_001933"
     CDS             7161..8558
                     /locus_tag="ACF3MF_001933"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFE3927914.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="ACF3MF_001934"
     CDS             8639..9079
                     /locus_tag="ACF3MF_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFE3927915.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="ACF3MF_001935"
     CDS             9227..9553
                     /locus_tag="ACF3MF_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFE3927916.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="ACF3MF_001936"
     CDS             9554..10303
                     /locus_tag="ACF3MF_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease prefix domain 1-containing protein"
                     /protein_id="HFE3927917.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELIGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="ACF3MF_001937"
     CDS             complement(10383..10838)
                     /locus_tag="ACF3MF_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFE3927918.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="ACF3MF_001938"
     CDS             complement(11265..11540)
                     /locus_tag="ACF3MF_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927919.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11834..12649
                     /gene="thiD"
                     /locus_tag="ACF3MF_001939"
     CDS             11834..12649
                     /gene="thiD"
                     /locus_tag="ACF3MF_001939"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HFE3927920.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(12978..14429)
                     /gene="cls"
                     /locus_tag="ACF3MF_001940"
     CDS             complement(12978..14429)
                     /gene="cls"
                     /locus_tag="ACF3MF_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFE3927921.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            14770..17436
                     /locus_tag="ACF3MF_001941"
     CDS             14770..17436
                     /locus_tag="ACF3MF_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFE3927922.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            17800..18552
                     /locus_tag="ACF3MF_001942"
     CDS             17800..18552
                     /locus_tag="ACF3MF_001942"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFE3927923.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(18574..19728)
                     /locus_tag="ACF3MF_001943"
     CDS             complement(18574..19728)
                     /locus_tag="ACF3MF_001943"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HFE3927924.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            complement(19998..21317)
                     /locus_tag="ACF3MF_001944"
     CDS             complement(19998..21317)
                     /locus_tag="ACF3MF_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HFE3927925.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
BASE COUNT         6787 a         3768 c         4365 g         6461 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaaattta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg ataggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaaa
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactgaaata tatataaatc aaatagtggt
    11641 tatttattat tagaatagcg aatacaaata aacgaccact attttctgat ttattgcaaa
    11701 tgttttttca aataaatttg attaccaaga aaaggtagtg gtatatttac tgagggatac
    11761 tttgaaaaac atatgataga aacagtaaca gtattatgaa aaatcttttt ataaaaatgg
    11821 aggaatcgat ttgatggaag atcagtatgt acaagcaatg acgatcgcag gatcagatag
    11881 cgatggaagc gcagggatgc aagcagatat gcatacattc tttacaagaa atgtttacgg
    11941 tgtttctgtc atgaccgcat gtgttgcagg taattcttac ggaatcggag caagtgtgac
    12001 attgccaaca gattttatcg acaaagaatt tgaactgatt gcgaaggact ttcaaatacg
    12061 tgcagctaaa acaggtatgc tagcagattc aaagttgatt gagacagttg taaaaaatta
    12121 ccaaaaatat gattttggac cattagtcgt ggatcccgta atcgtaacga aacatggaaa
    12181 tcttttacta gaagaatctg ctttgcaaag cttgaaagaa aagcttgtcc ctttggccga
    12241 agtactgaca cctaattttt atgaagcaga aaagctgact ggacggacat tagcagctga
    12301 agaagatttt gtgcaagcag caaaagaact gcaagatatg ggtgcaaaaa acgttatgat
    12361 caaaggacat catgctaaaa atgcgcagca agaaacagtc aatgactacg tattgttcga
    12421 atcaggaaaa tcattttggt taaatgcacc attttatcct accgaccgga tcaacggaac
    12481 tggcgattcg ctatctgcat gtattgcagc tgagttagcg aaaggaaaaa cagttgaaca
    12541 agcgatccga ttggcaaaag actatgtaaa ccgtgcaatt cgtgaagaaa taaatgtagg
    12601 gcacaaatat ggccccatca atcattgggc agctggtgaa ttagagtaaa agaaagaagt
    12661 tgtgaaaaag ttgccctgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg
    12721 tttttaactt ggttggactt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    12781 aggtcgtgag cctgccgtcc agctccgagt cacaaggaac aagttcaaaa aacagcttct
    12841 catgtttgtt gaatattgtg acttgtgacc gaggagttgg caggagaaca ccgtttgttc
    12901 ggaagaaggg actgtgacaa gatttttgtc acagtccctt taatcttagt atatttttct
    12961 ctacttgaat aaaaaaatta taggattgga gaaaataatc gagaaatttg ttgcttgaat
    13021 aatagccagt tagacatttc cttgactgtt tcagttgtca tggatgaaca atgtgtctca
    13081 tcttctttga actgagtagc aagttcttct aaaaactcag gatcgtaaat gacagcactt
    13141 gtttcaaaat tcaatcggta gctacgaata tcttgatttg ctgaacctac catgcagatt
    13201 tcatcatcca ttatcaatgt ttttgcatgg aggaagccgt tctcatagac aaggatttgt
    13261 acattttcct tgatcagctg ccgagcataa tattgtgttg ctcgataaat aaaaggatga
    13321 tccggtttgt tgggaatcat gattttcaca tctacaccag aggcagttgc gatttttaaa
    13381 gcagcaatga cactttcatc aggaacaagg taaggtgtct gtatccaaac acgtttttta
    13441 gcagaagtaa tcaatttgat aaatgaaagc ttgatttgtt ccctttcgtt attcggtccg
    13501 cttgaaacaa gctggatgga tgtatcagca agcttagatt catctcgatc tgctttttta
    13561 aagaaataat tcaaatgata gccgaccttt ttttcttcag gtaccgagac gttccagtct
    13621 gttaagaagc gaagctggag caaagaagaa gcggcaccga aaatccgtat atgcgtatcg
    13681 cgccaatagc cgaatttttt tgttgtattt acatattgat tggcaatatt gaaaccaccg
    13741 gtataactaa tctttccatc gatcacaacg atttttcggt gatcatggta attcaatcgg
    13801 aaacgaagta atgccctttg tgaggtaaca aatgtatgga catgtccacc atttttgatt
    13861 agacgattga aatcttttgc ttttgtgcca tgagagccaa atgcatcata taatattcga
    13921 acttccacgc cttctgcggc tttttcttct aaaacatgta agacttgctg gccgatatta
    13981 tctgtcacaa atgcgtaata ttcgatatgg atcgaatgtt tggctttttt tagatcttga
    14041 agcagtgaat ccaatttctc ttgtccgtct gtgagaagag tgacagaatt cattcttgtc
    14101 agcggcatac gatttaatga agagaagaag tcaacaaatt gctgtttgtc tttatcgccc
    14161 atgtcaggat cgtaatgttc aatggtatct cctctaaaag actgaaagtt ttctaattct
    14221 ttcaagtcac tttgtcggag atagaatttt ttcttatccg ttaatccacg tccgaaaaat
    14281 aaatataata caaagcccac cccaggaagg gcaaacaata ctaagagcca tgcccaaatg
    14341 gctgctacat ctcggggttt gatcaaaata gccaccaaag caataagtgc atttaataga
    14401 taaagggcgg ttataatact agataccaca aaaatgttcc tccttacata caataacatt
    14461 agtatagcat gatagaagaa agaagcctac caaggtgaat atacttttca ctcctttcat
    14521 gaaaatgtag gtaaatcggg ctaaagtagt tgctttttgt aggttaataa ggtaggatat
    14581 tagtacagtt gaatatctcc ttaggggagt aaccggcaac gtttgttgcg ataatatcaa
    14641 cagtaagtta accaaatggt tttctggtat tgtatgaaat ggtgagacct aagacaaatg
    14701 cgtatttgtc ttaggtctct tttttttcag acaggactag ggccaagatc aaaaaatggg
    14761 ggatgaaatt tggaaaacaa ggaacaagca caacaagcgg tctataaaga aacgatcgac
    14821 tcgttgatgc agcaaacgca gagctcaacc gatggattga gcaccacgca agcgaaggaa
    14881 aaattagaaa gagatggctt gaaccagcta aaagaaaagc cgaagaagcc aacttggaaa
    14941 ttgttcttag aaactttcaa agatgcaatg gttatcgtat tgctgattgt cgcactgatt
    15001 cagatggtca tgggtgacta catcgaattc ttagttattt ttgcagtatt gatgttgaat
    15061 tctataatca gtgttgtcca aacaaaaaaa gcagaaggtt ctttagaagc gttgaaaaac
    15121 ctttcagcgc ccgatgctcg agtgattcgt gatggtaagg aaaaaacgat tccggcaaac
    15181 gaacttgtgg taggagatat cgtgttgtta gacgcaggcg attatgtacc tgctgatgga
    15241 cgtttactag atgcgggatc attaaaagta gatgaaggta tgctgacagg agagtcgact
    15301 tctgcagaaa aagaagtaac ggatatcaca agtacggtac caatcggaga tcgtacaaat
    15361 atggtattca gtggaacgat cgtaacttac ggacgcggta aattcttagt gacttcaact
    15421 gggaataata cggagatcgg acaagttgct ggccttttgg aatcaacaac tgagcaagtc
    15481 actccgttac aacgaggtct ggataaattc agtaaaaaac taagtttggc tattttggca
    15541 ttgtctttat tgattttagg tatccaactg tttcgtattt atcttggaga aggtacagga
    15601 gatatgactg cagatatcgt cagcgcagtg atgtttgccg tagccgtagc cgtagctgct
    15661 attccagaag cattacagtc tatcgtaaca atcgtgttat ctttgggaac gaataaaatg
    15721 gcaaaacgtc atgccattat tcggaagctt ccagcagttg aaacacttgg ttcgacaagt
    15781 atcatctgta cagataagac tggtacattg acacaaaaca aaatgacagt tgttgactac
    15841 tttttaggta atggcgatac tggggatttc acaaatgacc cttcaaaatg gacagctgac
    15901 gaacgtcgct tgatcgaaat cagtgtttta gcgaatgatg catcgatcag tgaagacggt
    15961 actaaattgg gcgaccctac ggaagtagcg tttatcgact ttagtgaaaa attaaaccag
    16021 ccttatcagg aaatccgaaa caactaccca agacaagcag aacttccttt tgactcagat
    16081 cgaaaattaa tgtctactgg acacacaatt gataacaaaa attacttgtt tgttaaaggc
    16141 ggaccagata tcgtcttcca acgcagtaaa aaagtattgc taaatggtga agtcgttccg
    16201 atgacggatg aattgatgaa aaaattccaa gagcaaaatg aagctttttc aacacgcgca
    16261 ttacgtgtac tagcttttgc ttaccgtcca cttgataatt ttgatttatc atttgaagat
    16321 gaagacgatt tgatccttgt tggtttgctt gctatgatcg atcctccacg tgctgaagtg
    16381 actcaggcgg taacagaagc aagaagtgca ggaatcaaaa caatcatgat tactggtgac
    16441 cacaaaacaa cagctgttgc tatcgcaaaa caaatcggga tttttgaaga aggaaacctg
    16501 gctttgaccg ggacggaact agatgaattg acagaagatc aactaaacga agttttagaa
    16561 aaagtcactg tttatgcacg tgtttcacct gagaataaaa ttcgtatcgt tcgtgcttgg
    16621 caaaataaag gtcatatctc agctatgaca ggtgatggtg taaatgacgc accagcattg
    16681 aaacaagcag acatcggaat tgctatggga acgggtacag atgtggcaaa agatgcagca
    16741 gcgatggtat tgacggatga taactttgct tctattgtca gcgcagtaga agtaggacgt
    16801 aatgtgtttg ataatatcaa gaaagctatt tcttatctat ttgcaggaaa tttaggtgcg
    16861 atcattgcga tcatctttgc cttagttgct gactggtcca atccatttac agcattacaa
    16921 ctgttgttca tcaatttagt caatgattca ctgccagcaa ttgcattagg tacagaaaaa
    16981 gctgaacctg ctacgatgaa ccgcccgcca agagatccaa attcaggaat ctttacggac
    17041 aaaacattga tttctgtaac gtatcgtggt gtgctgattg ggattgctgt tatctttgct
    17101 caatggcttg gcatgcagca ttcacctgaa ttcggtgtag ccatgtcatt ttcaacattg
    17161 atttggtgtc ggacattgca aacattccca gcacgttcaa acacacaaac agctatccaa
    17221 gcagggttct tctctaacag aagtgtctta ctagctgtag ttgtatgtag cgcgctttac
    17281 tgcttaacaa tgatcccagg actgaaagaa gtcttctcta tcccatcagc atttggattg
    17341 acagaagtct ttacatgtat gggaatcgca cttgtgacaa ttgttttgat ggaaatcact
    17401 aaattgatca ttgtacgagt acaaggaaat aaataaaacg aatcaacgag gttgtgagcc
    17461 tgccgtttaa ttctgagtca caaggtgcaa tttcaacaaa cagcttctca tgtttgttga
    17521 atattgtgac ttgtgaccga agagttggca ggagaacacc gtttaaggaa gaagttgtaa
    17581 aatcagcatt ttgagctaat actgagggtc atctgattgg acactgttta ttcggaaaga
    17641 gggactttga cacgactttg gtcacagtcc ctttttttat ttatgataga cggaaagcca
    17701 atcattttat tattcatcaa aagagataga atagataaaa gaggagaatg atttattccg
    17761 aaaagtgaaa acatataaca aaaaattaga ggaaatcaaa tgaatgaaaa agaatgggat
    17821 gaatttgctg aagaatatta tgaaatccag caagaatcgc aagtaactat tgctgaagat
    17881 gtaaaaaatt atctgaaaac ggagaaagtc ctgcctgctg aaacagcagc agacgttgct
    17941 ggaggatctg gcagatttct ttccttagca aaagaaatta atcgctatga tttgatcgat
    18001 ttttcttcag gaatgctaga aaatgcaaaa aaagaagcag aaaaaaatga gttgccaaat
    18061 gtttccttta tcaaacagtc gttagaagaa tttatccaat caaatgagac atatgaaatg
    18121 gtttttacag cagcaaatcc agcattggta catcttattc aattagaaaa attgatgaaa
    18181 aagtcaagca aatggtgcgt gataatcaga gtagtggaat caatcgatga tgttttttat
    18241 cctatcgaaa agcaactagg aatgatagaa gaagatccta atacatcgcc agttgtaatg
    18301 gatcaatttg aaacatactt aattgatgaa ggattcaaag tgaagaaaaa agattttact
    18361 tattttacac aggaatcaat tactgaagaa ttgatgaagc tatactatga cgcgtacgca
    18421 aaagatcctg ttgtgaccag gtacattcgc aaactattca gtgaaaaacg agaaatcctt
    18481 agtacgacta agctgaccta tagactgctc ctttggtccg cagataaaaa aagaaccttt
    18541 cacgactcgt gaagggttct ttttatgatt ttattatatt ttgtagtaac gaatatcatt
    18601 ttcgatcttt gtaatcgaaa aaggtacatc tgaagtatat tctgcacatt ctccgtgttc
    18661 aggaagcgtc tcactgaaaa tcgtttcata ttcgtcaaca gtgatccgtg ttcgagaatc
    18721 tagcatctct tgatgagatt gtgcgaagag atattcttga tagttttctt ccagataacc
    18781 tgtaaaaaat tcacttactg caccagaacc gtagctgaat agaccgatgc gatctcctgg
    18841 ctgtagtgat ttcgaatttt ccagtagaga agttagcccc aggtataatg aaccagtgta
    18901 aagattaccg attcgtcggc tgtaacggat gctttcttca tagcgagcca taagacgttc
    18961 ctgattttct tcgtctgttt ggtctaatac gctttgcaat gccttttttc ccatcttagt
    19021 atacggaata tggaaagcaa tcgcctgata atcttcgagt cctcgacccg acaattcttt
    19081 atgtcgattc caaacttttt ggaatgattc gatatacgta gaattagata aaggaccatc
    19141 aacaacagga aattcgctat aatctggacg ccagaaatca tagatatctt ctgtcagaaa
    19201 tacgctgtcg tcttcaatcg ataaaatacg cgggttttga gtgatcatca tcgcaacagc
    19261 accgacacct tgcgtcactt caccaccgct tgccaagccg taacgagcaa tatcacttgc
    19321 tatgactagt acttttcgtt ctggatgatt tttgacatat tctttcgcca tgtgcaaagc
    19381 tgcggtgcca ccgtagcaag cctcttttac ttcaaaagaa cgagcaaaag attggatttt
    19441 cagtaaatgg tggataatta ccgcactcgc ttttgaatga tcaatcccgg attctgttcc
    19501 gacgatgacc atgtcgatta gctcacggtc tttttctgtt acgattttgc tggcagcatt
    19561 tgctcctagt gtaatgatgt cttcatttgc acgattgact gccatttggt cttgaccaat
    19621 ccctatatgg tattttgcag gatcatcccc acggctttct gccaactctg tcatatctaa
    19681 atataaatta ggaataaaaa aggaaagacg atcaatccct attttcattt caacacctct
    19741 ttacttatga taaaaaactt actttactaa ggtatcataa aaagattaaa agaacctgaa
    19801 taattcatag ctttaattct ttggcacatt ttattgaaat atgtatcact aatatcccta
    19861 tcaactgatt ttgactaaaa agttacttca aacattcact gttcaaaaat attgaggaat
    19921 aaattttggg tgtaaggcat tttgagcata cttctccctg gataacttcc cagtaaaaaa
    19981 atcgttagat tgttggatta gatccattga ctggctcgcc tcaggcgagc aaagaccctg
    20041 tagaattcat tctgatacac atgataacta gataatttga gatagactcg tctacccgtt
    20101 tggactaatt tcccagcaac tttcagaaac ttcaatcgaa tagaatgaat ggtcattccc
    20161 ttttggactt cttcaaagcc aatcgttctt aagaagttga ctaagttgta agctatcaag
    20221 ctgagcatca ttcggacatg attctccaaa aagcgaggac tgtctgtttt gtcaaagtaa
    20281 aagccagctt tcgcttcttt aatgaagttc tccattgtgc cacgtttggc atagatagaa
    20341 aagatggtat caggagaaac attttctgat agattcgtca cgataaattc atgtcgaaag
    20401 agtagttcgc ccgcttcacg tgttgagcgt atacacacgc gacgactttg tgaccaggat
    20461 tgtgcttgat aagtggtcga gaagtactga acttctcgtt cttcccactt ttgattatcg
    20521 ccataaagta ctgatttctc agctatttga cctagtctac gattattctt cagtcgaata
    20581 acataatgac tcttttttga ttcacacgaa tcatacacac caggtgtagc gaacccgctg
    20641 tctccacgaa ccaagatgtc agtgtttggt agagagtgat tatagtgctc taataaaggt
    20701 gtgagaaact cctttacgcc ttttgatgta tattgatttc ctgaacgtag ttcagctttt
    20761 aagaagtcac cagtcaatcc gtcaaaagct accaatggat ggtaaccata ggtttggtag
    20821 tgtgtattat aattcgtttg ttcttggtga ccaaatgtat ctgaatgggt cgaatctaaa
    20881 tcaatgatta attccgtatc attacggatg aggcgtgctt tatcgataag ttcttggttc
    20941 aaagcttgaa gttcatggat attctcctca gatagtcgat ctaaaaatcg ggaaagtgaa
    21001 gattgagaag cgagttcttt cctatctaaa acagctttaa acacaggatc ttgtctcagg
    21061 agattagctg cagaatcagc tgagtaacca gcaattaatt gcataatgaa ctgctcaagt
    21121 atggataagt tgtcatgagt aaaatacgct cgttcgtctt caatgtgaat gtgttgctta
    21181 gccagttcag aaaaaccaaa gatgttcatc agctctttca ctaggacgag acccgaatca
    21241 ctcgataatt gaccacctgt atgagaaata gtgatatttg aattgaattt tacttggttt
    21301 ttgtgtaagc tagtcatgaa aagaactcct ttcttttggt tggtttagtc actttaacca
    21361 tagcagaaag gggttctttt t
//
LOCUS       DAXQKX010000048        20661 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.049, whole genome shotgun sequence.
ACCESSION   DAXQKX010000048 DAXQKX010000000
VERSION     DAXQKX010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20661
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.049"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            168..362
                     /locus_tag="ACF3MF_001945"
     CDS             168..362
                     /locus_tag="ACF3MF_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927926.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            631..930
                     /locus_tag="ACF3MF_001946"
     CDS             631..930
                     /locus_tag="ACF3MF_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927927.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(1027..1461)
                     /locus_tag="ACF3MF_001947"
     CDS             complement(1027..1461)
                     /locus_tag="ACF3MF_001947"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFE3927928.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1693..2403)
                     /locus_tag="ACF3MF_001948"
     CDS             complement(1693..2403)
                     /locus_tag="ACF3MF_001948"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFE3927929.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2393..3253)
                     /locus_tag="ACF3MF_001949"
     CDS             complement(2393..3253)
                     /locus_tag="ACF3MF_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HFE3927930.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3258..3896)
                     /locus_tag="ACF3MF_001950"
     CDS             complement(3258..3896)
                     /locus_tag="ACF3MF_001950"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HFE3927931.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3911..4210)
                     /locus_tag="ACF3MF_001951"
     CDS             complement(3911..4210)
                     /locus_tag="ACF3MF_001951"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFE3927932.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4253..5737)
                     /locus_tag="ACF3MF_001952"
     CDS             complement(4253..5737)
                     /locus_tag="ACF3MF_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFE3927933.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQVLIFMGLILGCYWAVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5757..6218)
                     /locus_tag="ACF3MF_001953"
     CDS             complement(5757..6218)
                     /locus_tag="ACF3MF_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFE3927934.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="ACF3MF_001954"
     CDS             complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="ACF3MF_001954"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HFE3927935.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7521..8291
                     /locus_tag="ACF3MF_001955"
     CDS             7521..8291
                     /locus_tag="ACF3MF_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFE3927936.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8564..9391)
                     /locus_tag="ACF3MF_001956"
     CDS             complement(8564..9391)
                     /locus_tag="ACF3MF_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3927937.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9958..11193
                     /locus_tag="ACF3MF_001957"
     CDS             9958..11193
                     /locus_tag="ACF3MF_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFE3927938.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12192..12452)
                     /locus_tag="ACF3MF_001958"
     CDS             complement(12192..12452)
                     /locus_tag="ACF3MF_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFE3927939.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12479..13780)
                     /locus_tag="ACF3MF_001959"
     CDS             complement(12479..13780)
                     /locus_tag="ACF3MF_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFE3927940.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEKAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNATLLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPMIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14072..14530)
                     /locus_tag="ACF3MF_001960"
     CDS             complement(14072..14530)
                     /locus_tag="ACF3MF_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFE3927941.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14543..15373)
                     /locus_tag="ACF3MF_001961"
     CDS             complement(14543..15373)
                     /locus_tag="ACF3MF_001961"
                     /inference="COORDINATES: protein motif:HMM:NF023401.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HFE3927942.1"
                     /translation="MINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYD
                     KELQREIMPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYY
                     LYPDMVVEHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDI
                     AISLLNDDRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVETITLRKPISDFHKGL
                     MEAQVAAEKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK
                     "
     gene            complement(15386..15873)
                     /locus_tag="ACF3MF_001962"
                     /pseudo
     CDS             complement(15386..15873)
                     /locus_tag="ACF3MF_001962"
                     /inference="COORDINATES: protein motif:HMM:NF014148.4"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
     gene            complement(15884..17326)
                     /locus_tag="ACF3MF_001963"
     CDS             complement(15884..17326)
                     /locus_tag="ACF3MF_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFE3927943.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAIFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSGFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(17313..18077)
                     /locus_tag="ACF3MF_001964"
     CDS             complement(17313..18077)
                     /locus_tag="ACF3MF_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HFE3927944.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(18181..19056)
                     /locus_tag="ACF3MF_001965"
     CDS             complement(18181..19056)
                     /locus_tag="ACF3MF_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFE3927945.1"
                     /translation="MKESASCFVLSYSGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAIEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(19311..19395)
                     /locus_tag="ACF3MF_001966"
     tRNA            complement(19311..19395)
                     /locus_tag="ACF3MF_001966"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19359..19361),aa:Leu,seq:caa)
     gene            complement(19413..19484)
                     /locus_tag="ACF3MF_001967"
     tRNA            complement(19413..19484)
                     /locus_tag="ACF3MF_001967"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19450..19452),aa:Gln,seq:ttg)
     gene            complement(19494..19566)
                     /locus_tag="ACF3MF_001968"
     tRNA            complement(19494..19566)
                     /locus_tag="ACF3MF_001968"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19531..19533),aa:His,seq:gtg)
     gene            complement(19628..19712)
                     /locus_tag="ACF3MF_001969"
     tRNA            complement(19628..19712)
                     /locus_tag="ACF3MF_001969"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19676..19678),aa:Leu,seq:caa)
     gene            complement(19733..19803)
                     /locus_tag="ACF3MF_001970"
     tRNA            complement(19733..19803)
                     /locus_tag="ACF3MF_001970"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19769..19771),aa:Cys,seq:gca)
     gene            complement(19849..19920)
                     /locus_tag="ACF3MF_001971"
     tRNA            complement(19849..19920)
                     /locus_tag="ACF3MF_001971"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19886..19888),aa:Gln,seq:ttg)
     gene            complement(19932..20004)
                     /locus_tag="ACF3MF_001972"
     tRNA            complement(19932..20004)
                     /locus_tag="ACF3MF_001972"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19969..19971),aa:His,seq:gtg)
     gene            complement(20007..20080)
                     /locus_tag="ACF3MF_001973"
     tRNA            complement(20007..20080)
                     /locus_tag="ACF3MF_001973"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20046..20048),aa:Trp,seq:cca)
     gene            complement(20087..20167)
                     /locus_tag="ACF3MF_001974"
     tRNA            complement(20087..20167)
                     /locus_tag="ACF3MF_001974"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20131..20133),aa:Tyr,seq:gta)
     gene            complement(20169..20244)
                     /locus_tag="ACF3MF_001975"
     tRNA            complement(20169..20244)
                     /locus_tag="ACF3MF_001975"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20209..20211),aa:Phe,seq:gaa)
     gene            complement(20280..20352)
                     /locus_tag="ACF3MF_001976"
     tRNA            complement(20280..20352)
                     /locus_tag="ACF3MF_001976"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20317..20319),aa:Asp,seq:gtc)
     gene            complement(20362..20434)
                     /locus_tag="ACF3MF_001977"
     tRNA            complement(20362..20434)
                     /locus_tag="ACF3MF_001977"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20399..20401),aa:Val,seq:tac)
     gene            complement(20450..20521)
                     /locus_tag="ACF3MF_001978"
     tRNA            complement(20450..20521)
                     /locus_tag="ACF3MF_001978"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20486..20488),aa:Glu,seq:ttc)
     gene            complement(20536..20624)
                     /locus_tag="ACF3MF_001979"
     tRNA            complement(20536..20624)
                     /locus_tag="ACF3MF_001979"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20588..20590),aa:Ser,seq:gga)
BASE COUNT         6528 a         4318 c         3278 g         6537 t
ORIGIN      
        1 taagaacaat agccttttat tatatatatt attcaaatta gttatatcga gtgaaaaaaa
       61 ctttcaaatt gattcttttt atttatcata aagatataga tacataatca ttttcactta
      121 catatatttg aatattaact aaaaacagca agaaagaaga ggatcaaatg tattatgtag
      181 aagtaaaaac aaaaggcgtc aaaaacaaac aatatgtgaa aggtatcagt aacgaatatc
      241 ctttacttgg ttcatggaaa gaagctgctc ctttttccaa accatgtgcc ataaaaataa
      301 agaacgagct agaaaaagaa ctgacttgtg gtaaagctgt tgtagatatc atcgaaaagt
      361 aaatccaatg tatagaaagg aagatcacac atgaaaagcg acgtacaaat tgctaagatt
      421 atagaattag aagaagaaga cgcagtgttg acaattgaaa aaaaataaat gtttgtatac
      481 catatgatta tttcaatatg tatcctggaa ttggagatct cgtagagcta tatcaagatg
      541 aatcaaatat acttgtcatt catcatgaaa tatagagact tataaaattg tttattttta
      601 taatgtatca gtatagaaag gaaataaaac atggattata ctgttgaatt tgacagtgaa
      661 ctacttaagc aatttccaca agaagaacat ttcatgtata aagaagcaat ttcccacaaa
      721 gtgacagagt atttggagca taattttttt cgtataaagc cagtgcgtac tcgttcggca
      781 aaaggaatat acgagatgaa agtcaaaatt aataaaaaaa attatcgcat agcatttgct
      841 ttaaaaaaaa atcatgtgtt cattttttat attagttcga atttgcaaaa aattgtattt
      901 gataaagagg tgagtaaaaa aataaaatag ctgagcattg gaggatagat tgagtgatac
      961 taagtctatc ctcttgtttt tctaaagaac taagctagaa ttttttcttt tgtacgttat
     1021 tatatgttat ttgtcattac caaaaagcac cttttttctt ctagtatcta tgacataaga
     1081 aataccaccc atttccttta cttgaacaaa tcctactgat tcataaaatt tttttgtttt
     1141 ctcagtatca tctgtcaata attcgatttg gactggtcca taactagtga tcttctccaa
     1201 agcttcattc aaaagcactt tgcctattcc ttggcgctga tacctcggat gaatgaggat
     1261 atcttgaata aatgcgatcg tcgcaaaatc agtgatccaa cgaacgattc cgataatctt
     1321 cccttcccca ttacgcttta tcagagattc agattgttca aatgctctag ctaaccttgc
     1381 agtgtctttt gtgtaattcg tccaaccaac gctcttatat aattcagaaa tctcatcgat
     1441 cataagggaa tcaatattca tttttttctt cctttcttat acaattctcc ctctaataat
     1501 acagttcttt gactatttaa tctatcacat ataactctcc tgtaaagatt ctctcgattc
     1561 cttaaaattc ctctttcctt ttagaatgca tactttttga taaataaaaa ggttgtgata
     1621 aattttcttc acaacctctg tttctctcta tcaagtgtta tcttttaatt ttctaccctt
     1681 accctagcat ctctattgcc cgtagtatgc atactttcca tgtttgcgaa aataatgttt
     1741 atctagtaaa tattgcggga tttcacatat attggggttg atcagctcgt tttctttggc
     1801 catcagacaa atttcatcta agatcaaact gttttctact gctttcatag gtgaatcccc
     1861 ccatgtgaac ggtccatgtc catagacaag tactccaggg acttcgtttg gatctaattt
     1921 tctttcctta aacgtctcga caatcacatt ccctgtatga acttcgtaag cttctcttac
     1981 ttcttctttc gttaattggc gtgtacaagg aaccttacca taaaaagcat cagcatgagt
     2041 cgtgccataa gctggcaaat cgcgtcctgc ttgcgcccac atgacggagt gcgtggaatg
     2101 agtatgagta atagcagtta tatcttcaaa agtttgatac aaaacaacat gtgtggggag
     2161 atctgaagat ggttttaagc tatcttcttc tattatattt cccgacaaat ctgttaccac
     2221 catttgatct gcttgcatgc attcatatct gacaccgctt ggcttaatga cgatgactcc
     2281 tagctcacgg tccacttcac tcacattgcc ccaagtcaat ttgactaatc cgtatcgcgg
     2341 caatgccaga tttgcttcaa ggacacgttg cttcattgct gcaatttttt cttcacaaga
     2401 catcatagcc agcctccttc aatttagaac ttaagtagtc ttttgcctgc tggatttctc
     2461 ttcgaaagtc ttggcttttt tcactccaca tttcaatcag aaatgttcca tcataatcta
     2521 gacgtttcaa atgtcttaat aatccaagaa aatcaacaca accgctacca aaaggaacat
     2581 cacgaaactg gcctgaatat tcttttgtta cagggtaagt atcttttaag tggatagcag
     2641 tgatataatc gatccctttc tcaagttctc gagccggatt attttccggc catgcggaca
     2701 aattgcctag gtctggatat acttgtagaa aaggtgaatg aatctgttct ttgatttcta
     2761 aaaattttga aatggagttc ataaatggat catccatgat ttccacggaa agaatgatgc
     2821 catatttaga agcttccttt acgctttctt ttattccttc gataaagtct tctctggaat
     2881 tcattgattt ctcttcataa taaacatcgt atccagctat ttggattact ttgacgctta
     2941 gattatgcgc caaatggatt gcttttttca ttagttgttt cgctgctttt ttcttttctg
     3001 gatcagcaga accaaacgga aatcgccgat gcgcacttaa acaaatcgaa tggatacgta
     3061 caccggagct gaacatctct tctctcagct cagctatctt ttcttcagac caatctaatc
     3121 gtgctaaccg ctcatccgtc tcatcaatcg acatctcgat aaaatcgaag tccatttctt
     3181 ttacaaggga aaaacgttct ttccatgaaa tatctttggg taacgctttt tcataaatcc
     3241 caatttgagc catttcctta cccccagata cgaatgatct catctttgaa gttttgtgcg
     3301 gccttcatcg gatcatttgc tgctgtaata ccacgaccag tgataaaggt atacacatcg
     3361 atcccttcaa ataagtgtaa tgtgtgtgga tttaatccac cagttacaga aacattaaag
     3421 cctagttcaa tcagtttttt gatcttcgat aaatcttttt caccccaagt ttcaccagat
     3481 aacagcgcat cacggctttg atggtagatt acctgccgga taccgatgtt atgccaatcc
     3541 atggcttgtt caaaagtcca attgccgtag agttctactt gcaattcacc tatttctttt
     3601 tgtgctgcct ccatagttgg aatcgttgca caacaaatga ctgtcatcca gtctgctcct
     3661 gcttttgcaa cattactcgc cactgttcct ccagcgtctg cacatttcgt atcagcgact
     3721 agttttttat ctgggaacat actgcgaata cagcgaatcg ctttttgtcc ttcctgtaag
     3781 caaagaattg tgcccacttc aataatatct actacatcac caactttcat aacatctcct
     3841 aatgcatgtt ctaagtcatt gtgatctaac gcaatttgca aattcggcct gctcatctta
     3901 gttccttcct ttacttgttt ttttggtacc actttgtttc agcaaatttt tcactgattt
     3961 ctttgactga catcacattt ttgataccga taactgtaac tccttttttc tctgcctgag
     4021 taaacatatt caaaaaattg actggcgtaa aaactacatc gtattggcca gctgaacttt
     4081 ttccctctga aatggcacaa tgatggattt tggtaattgg tacgtttagt tctttcattg
     4141 ctttttccac acttctcatc atcatcaagc ttgttcctga tccatttgca cacgatacta
     4201 aaattctcat cttaatccct ccattatgag tgttgtctaa tcagattttc ttttatactc
     4261 tctgcttttc tgcatatgtg tcatagtctt ctacaatcaa aaaataacca tcaggatttt
     4321 tccgatattg taactgcgga atagccaata aaccaatgac aactacggca attccagcat
     4381 aacctaggac tttcatgatt actgtaaaca atggccaagc tgttgcccag tcgaacatcc
     4441 cgatataacc accgtatgtt gacatcccaa tccatgtagc gaataatgct gaaccgccta
     4501 cttgtatgat tcctgaaaga aacgggaaca ggcaagcggc tttgaatcca cctcggttat
     4561 tggcataaac tgctataacg gcattatcaa agaacaacgg aatgaaaccg gctatgacga
     4621 tcgttggtga tttcaataaa atcagtaaac caatcatcaa aaactgtccc aaagcaccaa
     4681 acaagaaccc aatcgttacc gcatttggcg aaccaaagcc aaaagtagca gctacgtcaa
     4741 ttcctggaac agctcctggt aaaatcgtgt ttgagattcc ttggaaagat tgagttagtt
     4801 catcgacgaa tgtccgaaca cctaattgca agatcgccag atataccgca aaatttaaag
     4861 aagtcgtcat aatgtagaat aagaaactct gcccttcttg catgaattgc gcttgaatca
     4921 aataatcttt gcctagtaca atcagaatga tcccaaagaa aaatagcatg agtaacgaag
     4981 tagcaaccat attctcattg aaaatcgaca agaatcctgg taatttgata tcttcaattt
     5041 ttttgtcttg cttgattgat ctatttttct tttcatcccg ctttttcatc cactcagcta
     5101 attttgcaaa tataaagatt ccgaacattt gctgatgtgc cactgcaaat ccggcacctt
     5161 ctgtcaattc ctgcgtgatt cctactgtta agttagaagc tactgcccaa taacaaccta
     5221 aaatcagtcc cataaaaatc aatacttgta tcctacctag atcaggaaag caaaacagta
     5281 aaatccaaaa agcggtagct gcttgttgaa cctgaacgtt tccggtagtg aaaacggaac
     5341 gcagtttcgt atatttctga aaacggacta ataagatatt taaaacaaat gcaatcagta
     5401 ataaaatcat cacatctcca aaggtacggc caaatgtctc cattaatcca gcatccacag
     5461 cattttgtcc aaaataagga tctgtaacca tggcatccaa attgaaccgt tcctttagtc
     5521 caaccaagat tggccgaaaa ttattgacca aaccaccaga gccaacagtc aaaataaagt
     5581 aaccgaccgt tgcctttaag aatccagcga tgcattcatg aagcgggcgt ttcagcaaaa
     5641 tatagcctaa taacacgata aaaccaatca ggtatgctgg ctgcgtcaag atatttgttg
     5701 caaaatacgt ccaaatgctt aacaaaaatt cccccatctt ttttctcctc tatcaattaa
     5761 ttatattctg ccatcacaac ttggtaatca tcgatggagt tcgtagagat gagacgctca
     5821 accaatccat ctgtcattaa taattcggat aatttttgga tattttctag atgttcttct
     5881 ggatcttttg ctgcgagtgt aaaaaacaaa ctagccgttt tctcctcatt ctccccttca
     5941 ctttcaaaac ggattggctg tttcaacttg gtaaatgaaa tagctgttcc aaaaacacca
     6001 tcactttttt ctgaagaatg cggcattgct acttgaggtg cgatcacaat ataaggaccg
     6061 tatttttcta cacaatggat gatctcctcc acatacgttt catcaataat ttccttatcg
     6121 atcaatacaa gacagctttc ggcgatagct tcacgccaat ccgtgatttc tttatctggg
     6181 taatgaatca attgatggtc aaaaaagtat ttcagcaaga aactcccctt ctttcttata
     6241 aaaacgacgg aaacggtgta tcattttcaa tcgagaagac atcttcaaat cctcgataaa
     6301 aattaaactc aagatcatct ttgtttgtcg gatagatgaa tttcccgcct acttgccaga
     6361 tataaggttt aaatccatac ttcaggcgat cctttttgaa tttccaaatt tcagtgatct
     6421 cttttggatc agccataaaa ttagaccaaa tatcgtagtg gacaggaatc actacttttg
     6481 cattcaatga ctccgccatg cgcagcatat caacagaagt aactttgtct gttatccctc
     6541 gtgggttttc accataggcc cctaaacaga catcgatttt gtgttcatta ccatgtttgg
     6601 caaataaatt ggagtaatgt gaatctcctg catgataaag attccctcct gatgtttcga
     6661 ataaatagtt tactgcaatt tgatccatct cctgaggcat ttttcctttt aatacctctt
     6721 ctggatcttc acaagtgacc aacgctgtcc gatcaaacgc ttctaaagct actacattga
     6781 tgtctttgat tttgactgca tcacctggct ttactgtaat cgttttttct tcaggaattc
     6841 cccatttttg ccacgtgcga accacttctt ttggcccaat gaatgttgct tcaggacaat
     6901 tttgatgaac tgctgcggct gtatggatat ctagatgatc ggaatggata tgtgtaacga
     6961 ttaaagcgtc tacatttttt atcgcaaaag gatcgattac gaaaggctga gtacgtaaat
     7021 taggctgcat attttgaacg ccactcatac gcatcatctg atggcctttt ttcatcatgc
     7081 cattcccatg actacgtttt cccgtcccac accatagatc acataaaata ttcgttcctt
     7141 catgactttt cagccaaatt cccgtacagc ccagccacca catagcaaaa gttccaggat
     7201 ccactacttc tgtttcgatt tcttcattca agtatgtgcc ccactcagga aatgtttcta
     7261 ctaaccactt ttcttttgtt acttcattga cagttttact catttgcttg ctccccccat
     7321 atcgttgttc caacttacaa gtaaatatta atgtgtatca gcatccatga aaaccctttt
     7381 atatgaccgt ttgtttttta tatgattttc tttcagtaat caatgattgt ttcagtataa
     7441 taaagacaga tatgaatgtt taaatgaaca actagtcaaa taaatccatg gatcaagatg
     7501 tccctcagga ggcaaaagtc atgaaaaact cacttgtcaa tattgaaaaa cgtcaaaaag
     7561 aaattttgga actgcttcag cagactgaac aactatcaac tttcgaatta gctgaatccc
     7621 ttgatgtatc tattagtacg atacgaagag atttaaattt attagaagaa aaaaacgaga
     7681 tcatacgcaa ttacggttat tgttcttata attacaaaaa ccagactgat tttgatcaat
     7741 ctggtcctga aaggattaaa caagcgattg ccagagaagc tagtaaatac attaacgatt
     7801 atgatacgct gtttatcaat tctagctcga ctgcgttgaa aacactggat tttcttcaat
     7861 ctaaccattt gacagtcatt acaaacaacg tgaaaatcaa ttactctccg cacaaagata
     7921 attgtagtta tattttaact ggtggagaga tgcgctttcc aaaagaagca ctagtgggcg
     7981 acatcgcatt aaatacgatt tcttcagtca atgcagacat ttgtatcatt ggctgtagcg
     8041 gagtcgatgt agtacatggg gtcacaacaa agatattaaa tgaatcaacg atcaacgaaa
     8101 tgatggtcaa caagacaatc aaatgtaaga ttttagtcgc tgatcatcga aaaatcggac
     8161 tgacatcaaa gttcaagatt gctgatattt cagtctttga ttatttgatc actgataaat
     8221 tttgttctga aaaagtatta gaggagatca gaaatacggg gataaaaacc attcaagtag
     8281 attcatttta agaaccagga cgtaaatatg taaataggat tatcaaaaaa atgaataaca
     8341 aatttatcga taaatgaaaa acacgctacg ctcaaattga taaaggaatc ccaagatgta
     8401 tccatccaat cgataccatc ataatctatt gcttctttta taaccgttat atgttgccta
     8461 aataggaatc aaacaatatc gaaaaaagga ggtatgacaa aagtcacacc tccttttttc
     8521 gaataaacgg tattcaaatc agaacactga tttcacaacc actttatttc aggtcgtttt
     8581 caatcacctt taccgcgtaa tcatttccgt tgaaacgcgc tatttttttt gcgtccatat
     8641 atctttctaa ataatcatct tctcctaatt gcttatggca agaagcaatt tcataaagca
     8701 agtattccaa tgcataagtc gatttatgtt tcttattata ctcaataccc ttctcacata
     8761 attggattgc tttatcataa tcctcgattt tacggtaata ggtggcgata tcataatata
     8821 caatgcagac catcagatta tcaaaatcag tctcactcaa tattttaagt gtacgctcca
     8881 cataaacttt cgcaaaatct aattctcctt ttgacaagta gatcattgcc acgtttgcag
     8941 ctgcttgtaa gtgatggata tctgtttcgg tcgtttgttc caacacttga ttaaaataaa
     9001 ataatgctgc atctggtttt ttcgcataaa gatgatcaag cagtccttga taaaataaaa
     9061 tttgatttaa aagatcagaa ttacttactt tttcctgatc gatcgtttgt aaaattttat
     9121 aagattcttg gtattttgat acagaattca atgattgaat ctcatttatt tttttcctga
     9181 ttttgtcttc ttctgtttct actaatatat cggagatctc gacattcagc tttttgcaaa
     9241 gcgcacttaa gatattgatg cctggcgaca tattcttgtt ttcgatattg ctgacagttg
     9301 cttgttcaca aatgccttct gctaattgta cttgtgttaa cccctttttc tttcggtatt
     9361 cttttagtaa tgctccatct actttaatca aaacaatttc cttcccttta aaaaattatt
     9421 tctcctttat atcatacaca aaaaaaagtt ctaaacaacc aaaaatgttt agaacagaat
     9481 aaaaatttta attttaaaat aatattcaaa ttaaacaact ggcgtatctg ctccttgatt
     9541 tctttttgtg ttatctgaat aattatcgtt tacagttata acacatagtg aaaattgtca
     9601 tggcgagaaa gtctaagaat atttttaaac ataactattt ctttcttacg tgtgtataat
     9661 gacgacagca cacctatcaa ttaatataat tattttattt tttatgttct catgtttatt
     9721 tttaatgaca caacttctcg tatttatctg gcacaacata taaatcgatc aaaaaattgt
     9781 tgcgtgtttt tttgaaaatt ggagtttcaa cttgattaca aaatttaaat ttagaagttg
     9841 tgaaaacagc gagagacagt ttaatattca aaatatacat aggctactcg aacgctgtgt
     9901 tttttagtat actagtaaga aacgaaggga tagactcatt ccaataagga ggatttcatg
     9961 aagacaattc tttttgctcc tgcagtattc aatttagctg agacaacacg aatgattgag
    10021 gttgccaaag ctatgaaaga ccgttattac tgtgtattct ttggcttttc taaaactttt
    10081 gctcctttga tcacagaaag tggctttgag tatcatttac tagcgccgat ccttacgaaa
    10141 aaacaagaag aacaaatcat aaaatttgac cagttgcgta cacttaaaaa cccttttacc
    10201 aaagaaatgg ttgcctctcg tatcactagt gaacagagtc tgattgctaa gtttgagcct
    10261 cgactgattg tgacaggttc gaatgtgaca atttttttat cggcccgcaa taaaaagatt
    10321 cctttagtat atgttaaacc ctatgctttg agtgaacctt tttttcaatc agagcatgcg
    10381 ctgatgcccc acgagttacg tttcttcggc cctttaagca atcccctttg gcactggaca
    10441 aaaaagcgta tagtaaatac ccgatggatc cccaatgcct tcaaacacgc tgcacaaaaa
    10501 gaaatgcttc ctttaccaaa aacaagttta caaatgatgg atgctgatct aaatctcatc
    10561 acaacgccta aactattttt ggaagaagaa cagctgccgg aaaattatcg aatcgttggt
    10621 ccaatttttg ctaagctcag tacttccttg cctgaagaag tgctaacttt tatacagcga
    10681 aagcaacaag aaagaaaacg tattatctat ttcgcaatgg gtagttcagg caatccgcgt
    10741 atgttacgca aaattttgtt cttcttacaa aaacaaccgg atctagcggt tattgcacct
    10801 attgactatc tgcttgatga cattcaatct gactcagaag atcttttaat aacagaatat
    10861 ctgtctagtc atcttttgca tgaattcatt gatttttctt ttatccacgg cggggaaggg
    10921 accgtccaaa ctgcctgtga atccggcaaa ccgtttatcg gtgtggggat gcaatttgag
    10981 caaagctgta atattgacta ttgtgtaaaa tacggaaacg caatcgccct cacaaaacca
    11041 gtgactgaaa gaaaactgca gattgctctg cgcgaagttt cttcacccaa gattcgtcag
    11101 caggcacgca cgctgcaagc cgtttttcca ataaatggtc cacaacaagc aattcaagaa
    11161 atcgaaacct tcctgagcaa ccacccaata tagtttcaag tagaaaaagc ttttttaata
    11221 gagactcatc agtaatttcg ctattcgaga cccagacagt gaaaatacaa aaaaagtaaa
    11281 tagtggattg aaaagttaga gttacttaaa ttacggtgtc taaaaaacac aaaatcatcc
    11341 ttaaaataaa agatctgacg caatccaaat gagcataggt agcgtctgcc atttattctt
    11401 agtcaaattc tttgacacct ttctctggtt ggatcatctc aacgtttctt caaaagaaag
    11461 accataataa ttaggcaaat acattttctt aaaatgtgtc atatagatct agaagcatcg
    11521 ctttgtagag atttgtgctg ctagtccctt caacaattac taaatcaaat gtaggattta
    11581 ccactttatc tttgataatc aacctccctc ttctgttgag acaatgatct cgcaatccga
    11641 tgcatactcc tatataaact gccagcaatc cccacatgct gagtagatca tgtcagaatg
    11701 ttctatgtcg tcagcaacga taaactaaaa gtcacgttca ccatgactga ttgctattcc
    11761 cagcgcaatt atttctatac acgtttcatg atttgaataa acactctcat catacatatt
    11821 accattcata caccatactg cagcccctac tatatggttg taagctccca aatctatatt
    11881 tgccttgatc actttggtag tagatcgact aattcttaat ccattgctga taaaattttc
    11941 atttttgcct ccttctttct gccaaaacag ttaaaacaat aataatcttt atgtaaaaaa
    12001 gggctgtgac aaaagccttg tcacagtccc atattccgaa taaacggtgg tcaaaagctt
    12061 gcatctgcgg taataagttc aaccaaacga aaaataagcc aacatttcac aaaaatttaa
    12121 gaagcaattt tcgtaaattt cttcttattt cttgaagcta accacttctg tcacaaccac
    12181 ttttagaaca tttaaagctt cgatgtgaca aaccatctat gctgctcgat cataaaattg
    12241 atagcaaaaa ttccacaaag tacatatgtc ccccatgaaa acaaaacatt catatgcggt
    12301 acaatgatct ttggaagaat cacgatcaaa aatgatgcca gtgcccaaat ccatcgattg
    12361 atttgaatat gatatgtagc tagcatattc aatataaggt gactagccgt taataaaaag
    12421 ataaaaacaa aaaataaaat cagccaatac attgtttccc accttctaaa aaccaaactt
    12481 agacagtttg gacttcgttt tctccacgac tttgttcatc tgacagcatc tttttatcat
    12541 aagcttttac aaatggataa tagataataa atgctatcaa tgtgttgatc atgatcaaga
    12601 taacaacacg ccagtcattt cctgctgaaa gataaccgcc gattggagct ggtaatgtcc
    12661 aagttggcaa aacagtaaat ctattgacca tttctaattt gactgcaaaa taactgataa
    12721 tagtcaaaac taaaggaact aagttgaacg ggatgaacat gtaaggattc aacatcatag
    12781 gagctccaaa aatcatgggc tcattgatat tgaagatacc aggaataata gaaaaacgac
    12841 caacctcttt caagaatttt gatttacaga agaatataaa caaaacagat accacgatcg
    12901 ttgctcctgc accaccaatt gttaccgtcc attgataaaa ctgttcagga gcgatatagg
    12961 gtaattgggt ggcagctgta ccatctgcca atgcctttgc attctcatcc aacatgatca
    13021 gccacattgg acgaacaaca gcccctacaa tactcatgcc atggatacca aatgaccaca
    13081 acaaatggat caaaaacatt ggtagtaaaa caccaagcaa attattccct aaaatattgg
    13141 ttaaaggctc gaataacgat aataaggtag cgtttacatc aaagcccgcg acgcttcgaa
    13201 tcagccaagt aattgttaaa atgactgcac ctggaatcaa tgcctcaaaa ctacgggcaa
    13261 cagcaggtgg cacttgttct ggcattttga tagtaatatt tcgattttta aagaaacgat
    13321 atacttccac tgcaaaaatc atagataaga tccccgcaaa catcccagat gctcccaaag
    13381 aactcatagg taagacccag ccaagaggtg ccttttcagg agttaaaacg tttacaggaa
    13441 cttgtaacat aaagaacgtt cctaaagata atataccacc tgtcacacta tctaatccat
    13501 atgatttagc tagatccgaa cccataacaa aagttgcata aatagccatc aatcccatcg
    13561 tcatcctaaa aggtaaaaca atcgttgccg aataaggggc aataaattca ttccatccag
    13621 gaaacggtaa attgataaag accataaaaa atgtcccaat caaaatcaat gacaatgttg
    13681 aaacaacccc attacgaatt gctaataaat gacgctgtgt accaattttt gccattggtg
    13741 ggacaagttt ctcttcgacc catttcatca gcttttccac taaaaccact ccttttcaat
    13801 aaaatatgaa ccattcattg catgacaacg caaagaatgt tcataactaa ttatataatt
    13861 aagaaatttt atttcaatat attctcttaa ataatcaaat ttatttttaa gaatcctgaa
    13921 aataagtttt ctaaatcata ggagcaacaa aaaaattcga taattaacaa aaatcaaaat
    13981 gattaaatct agtgattgaa acttatcatt tcaaaaaaat tttgtaaatt cacccataaa
    14041 tatcacccta tttaactttt ttcatcgtac actaaaattc aaaacaacta tctttaatct
    14101 ttacttcttg gttttgtttt aataaatttc cttcaaaaat gcctggagaa actacaatga
    14161 tcaccgtatc tttttgtgct tgctccaact tcttcaaatc tataatagct aacagtgtcc
    14221 cttcttttac ctcctggtta ctttcaaccc gtatctgaaa cggacttcct tcgagttcaa
    14281 ctgtatctaa acccatatgg atcagtattt ttctgccaga ttcactttcg atcgttatgg
    14341 catgtcgggt aggaaatata ttatcgatta ttcctttaac tggcgcatgg atatatccat
    14401 catgattcgt tatagcgtat ccaactccta tcatttttga agaaaagacc tcgtctttta
    14461 ctgctgttaa tggaataatt tgaccactag ctacagcttt tagaatgttt cttgttttaa
    14521 agaaatgcac tttttatcac ctctacttta atgctggcca atattttttg tttactttga
    14581 tcatttcatc tagtattttt tttgcgactc tggcatttgg tacggtttga ttcaatgtaa
    14641 atgcttgtaa agctttttga taagaacctt caaagtaagc atctactagt aacttctctg
    14701 ctgcaacttg tgcctccatc aatcctttat gaaaatcact gattggtttt cttagtgtaa
    14761 ttgtctccac accagttgca ccaacatatg ccggtatttc aacaactgca tctgaccgta
    14821 gattcggaat cgccccttga ttaggaacga ttagcataaa gcgacgacga tcatcattca
    14881 acaaggaaat agctatatcg acgatatatt gtccatgctc cccaaaatta aagttcaata
    14941 cttcttccac aataccgcgg cgtattttat cagccatttc tttggtattt ttctctcgtc
    15001 catccatgac catattagca cgtgtatact ctttgtcagt atgctcaacg accatatcag
    15061 gatataagta atactctaag taattattcg ggatattact tggaaaattt ttcgtgatga
    15121 ctgacatcat ttgaaaggtt ttttgccaag ttttgtctcc tatattaaaa tcggcgactt
    15181 gcatttcttt tgttattagt ttttcaataa tctctggcat aatttctcgt tgcaattctt
    15241 tatcataaat cgatgtatac cagccaaagt ggtttaaacc ataatacgta acgatccaat
    15301 tcttacgatc ataaccgtaa ttcactgcaa tcgtttcttc aattgaaata gtcatatcac
    15361 aggcattaat catttttaca ttcggatatt tacgacgaac agcttcagaa acgatcgact
    15421 ctggatttgt ataattcaaa atccatgctt tgggggcata gtcttgtata tgatcgacaa
    15481 tttccaataa acctttgatt gagcgcatcc cataagcaaa tcctccgagt ccacacgttt
    15541 cctgtcctac taatccatgt ttaagtggaa tcttttcgtc cttttctcgc atctccaatc
    15601 ctccaacacg aatttgtgag aaaacaaaat cgcatcctgt aaaagcaagc tttggatcat
    15661 ccgttgcacg aatgcgaata tttgaaaaac cttttttttc agcataaatt taacaatcaa
    15721 gtacatatcc atatttcttt cttcatcaat atcatataaa cgtatttcag ataatggcaa
    15781 ccgtttttca ttgttcaaaa tggcttgaac gattcctggt gtatacgtac tcccgcctcc
    15841 agctatagtg ataatctgtt ttttcatcat catcttttcc tttctattct tctaataatt
    15901 tattgaattc tgccataaca taagtcactt ctaagccgat gataatttga taattttttt
    15961 cagttggttt aatgatcccg cttatcccta attgcttgat tcgctgttcc tcgaccatgg
    16021 tgggatccac tacctctacc cgtaggcgtg tattacaact atagacatcc aggatattgg
    16081 cttttcctcc aaacgcttgt agcatttttg ttgccatata ttcataattt ttacttgcta
    16141 accctaactc tgtttcttct aaggttactt cattgccaaa ctctgcctta gcttcacgtc
    16201 ctaatgtctg aatgtttctc ttattgatca aataataaaa agtaacgtaa tacaaggcaa
    16261 aaaagaaaat tccgattgga agaatcaaaa tagcattggt agcgattcga aaattgatga
    16321 gataatcaac aatacatgct ccgaatgtaa aaccaattcg tatattgaat aagtaacaga
    16381 caatccctgc taaaccggca aaaagtgcat ggatcacgta caacatagga gaaagaaaca
    16441 tgaaactaaa ttcaacaggc tcagtgatat ttgcaataaa tgaagttcct gcaccgcttc
    16501 ccatgattcc tttgaccatc tctttatttt ctttataagc tgctttatag atagctagac
    16561 atatagctgg tataccaaac atcattacta caaaaaaacc tgataaaaac agtccagcct
    16621 gaggatctcc gttgataaag cgtgtcatct ctcctctgaa aacttccttg ctaggagatg
    16681 tatagcttcc taaatcgtaa taaatatacg tattcaacac atggtgcagt ccaaagggga
    16741 tcagcaaacg attcaaaaac ataaatatcc ccacacctaa tgcccccata tcaacgagca
    16801 gttttgcaaa attatcaatc ccaatttgga tgagcggcca gataaagccc aaaaaaatag
    16861 ctgcgattgt ttgtagaatc atcaccatag tcaatgggaa tttttcgccc gcaaaataag
    16921 aaaaaactac tggtaatttt tgttctttaa agcgattata cgtccatgcc gctactaaac
    16981 cggaaataat tccaccaaaa atccccatat tcacttctgg gtccatgatt tctaagcctt
    17041 ttttcaaggt agcaatcgct aaaaaaccag taagtgcagg tattcctttg tccttatttt
    17101 tgacaaaacc gattgcaact cctatagcaa ataagatatc caagtttcca aaaacggcat
    17161 ttccagctgc accaattact gggatgttca gcatatcatc agctgataaa cgcatgatca
    17221 atcccgctaa tggcatcgct gcaactggaa gtagcatcgc tcttccaagc ttctgcacat
    17281 ttgatttaac attcattttt attcctcctc tattaaatat cctcatatgt tactaactca
    17341 atcaaaggat catttttcac tttttgagca aatgctgaat gaattaaaaa ttcgacttgg
    17401 tgagtacgag gatacacaaa acttgaacca tttaacaatt cctgatccaa atacgctgcg
    17461 tgacacatga cttcgatcgt tttatcttct ctcaatatca tgagtaaact tgccaaatat
    17521 tcttccacac tcgtattgat ttgtcgtttt ttttcatcag tttctcctac gacatcgaaa
    17581 caaggctcaa aataatcgac atgacgaact tcatcttttc gttcaaagtt gctccgaacc
    17641 ggcaaatcat atttttttgc taatgtaaca actacctcct ggttttcatc caaagtatga
    17701 gtatgatgat gactgtctaa atgagttggt atgatccccg catgataaat tttttgaatc
    17761 tgagcattcc attcctgata cagttgatct ttgtcaatgt taaatggatg ctgataataa
    17821 gataaggatc tgaactctcc gctttcgata agagtatcga cagttttgag aagtggtttg
    17881 ccacacgtca atgttaaatg gactcctaca cctagcctag gcatttcctt tcttagtttc
    17941 acagcgtgct cgaaacccgg catatttgcc atcaatgtag ttgatgtcaa aattcctcgc
    18001 tgataagcat ccataatccc ataattcaca ccatggctat agccaaaatc atccgaatta
    18061 aaaatcactt ttcccatttc attctccttc ttttttctac taaaataggc gcaaccaaat
    18121 aatcatagtc catttactat gtgtcatttg gttgcgccta tagatagtta cgcccttatt
    18181 ttaatagatt cgtgctagat gaattgccaa atagatgatt tcattttctt gaatggcaag
    18241 ttgaaattgc tgttcgatga tatctttaat ctttagtgct gtacaatacg ctttgctatg
    18301 tttaaatgtt tcagtaaaaa aaccaatatt ttctactggc gtttcttcct gataaatcaa
    18361 gcgtttaacc aggaatttga tatgaaccat taagcgatga taagtcagtg attctttatc
    18421 ataaacgttt gaataggatt tttctagatg ggacaaaatc gtggtcgtca tttctactat
    18481 ttttaagctc tttaaactat taggctctcc tagctcagca ttaatgatat gcatagtgat
    18541 gaatcctact tcatttgacc ctaactcggt ttgatatcga tgattgattc gctcgaccac
    18601 ttctattgct atatcatatt catttggata aaggaatctc atttctggca acataattgc
    18661 tgtgacatct ctatcttctc tttttcgttg aatagcaaaa taaatatgat ctgtcaatgt
    18721 aatatagata tttgaatcta atggagagga gatcctagct gttatcagtt caatcacttc
    18781 ttccgcaaaa tccataaatt cgattggaat ctgcgagact atctcactga atcgtttgat
    18841 cttttcttta gaatctaata caaataattt gtcagcatcc tcaacatcaa atggcttact
    18901 cactttagca gaaaagccaa tccctttccc catcgcaatt ttttctattc catcgtcatc
    18961 gatcaataca gcattatgat tcagcttttt catcacatac accgttaatt cacctccact
    19021 atatgataaa acaaaacaac ttgcagactc cttcatacat atttttgtct ccaaacaatt
    19081 tttaaagaca aaaaacgacc taagaaagaa ccctttctta ggtcgtgcct aattgaatag
    19141 tagcacccta cataatttac aaaaatagtt taacacataa taaaagcgtt atcaatatct
    19201 tttttactcg ttttatgata atacttgtat cgaattgatt tggaggtaat tacataaaaa
    19261 caaaaaaaat atagcaactc tctataagaa agttgctata ttgataatta taccggcggc
    19321 cggggtcgaa ccggcacgtc ctcaacggac actggatttt gagtccagcg cgtctgccaa
    19381 ttccgccacg ccggcaaatt taaaaataat aactggggta gctggattcg aaccaacgca
    19441 tgagggagtc aaagtccctt gccttaccgc ttggctatac cccaagaata aagggcgaat
    19501 gatgggaatc gaacccacga atgccggagc cacaatccgg tgcgttaacc acttcgccac
    19561 attcgccatc ataaaagatg ttatttaatt tctcaataaa aaactaagat gaagacatct
    19621 tagtcaatac cggcggccgg ggtcgaaccg gcacgccctc aacgggcact ggattttgag
    19681 tccagcgcgt ctgccaattc cgccacgccg gcaagttgat ttattagtac taaggcggta
    19741 accggatttg aaccggtgat gaaggttttg cagacctctg ccttaccact tggctatacc
    19801 gccattatac tattatcaat ctacaaaata aagaataaat tatagaaact ggggtagctg
    19861 gattcgaacc aacgcatgag ggagtcaaag tcccttgcct taccgcttgg ctatacccca
    19921 agaataaaaa gggcgaatga tgggaatcga acccacgaat gccggagcca caatccggtg
    19981 cgttaaccac ttcgccacat tcgccatggc aggggcagca ggaattgaac ccacactaac
    20041 ggttttggag accgctgttc tacctttaaa ctatgcccct ataaaatgga ggagagtgga
    20101 ttcgaaccac tgaaccctaa ggaacggatt tacagtccgt cgcgtttagc cacttcgcta
    20161 ctcctccatg gtggcgcggg acagaatcga actgccgaca cacggagctt caatccgttg
    20221 ctctaccaac tgagctaccg cgccatattt taaaattatt aattgaataa caagaacgac
    20281 ggttccgacg ggaatcgaac ccgcgatctc ctgcgtgaca ggcaggcatg ttaaccccta
    20341 caccacggaa ccagttcatt atggaggtta acgggatcga accgctgacc ctctgcttgt
    20401 aaggcagatg ctctcccagc tgagctaaac ctccaacatt caattaaaat gacccgtacg
    20461 ggattcgaac ccgtgttacc gccgtgaaag ggcggtgtct taaccgcttg accaacgggc
    20521 caggtaaatt tgctacggag agtaagggat tcgaaccctt gagacagttt gcaccatcta
    20581 catgatttcc aatcatgctc cttcggcctc tcggacaact ctccagagtg aaagaagctc
    20641 aatactcttt ctcaaaatga g
//
LOCUS       DAXQKX010000049        20157 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.050, whole genome shotgun sequence.
ACCESSION   DAXQKX010000049 DAXQKX010000000
VERSION     DAXQKX010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20157
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.050"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            102..2144
                     /locus_tag="ACF3MF_001980"
     CDS             102..2144
                     /locus_tag="ACF3MF_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFE3927946.1"
                     /translation="MNKRIREILKLIIKNPEMKLSTLTSELDLTRRQINYAINQFNEE
                     LKTKNIPLIQRSHSGNITVPIEVIQMISQPDYDIGDDQELVVLTDSERQALIVMTLIA
                     NIDYISLDHLVDAVDVSKTTVMEDIKRTEPFIRNYSLTIRYNRMNGYQLVGSEHRILQ
                     LLSDLVKRFPIFRREMIRRKLAQDVSEEEIVHLIHNMEQMLHLSYSDESVDYLQTSAR
                     FLVSRGIKMSDKHAFFPDDVTDTPEFRMLMILVHETGWSLSKSYMEWFTLLFLTSNIF
                     ESKTTQNYDSDQELRKLISQMVENFQNQTLILIDDREDFERRILSHLRPACFRIRYNL
                     SLGVYSIDSLIKDSNHAILIDLMKELIIPIENWLNKAFPNDELDLLSYYFGYQLSNHN
                     KLNKQRQRAVVVCTNGVMVSKLVRANMEKLFPEIHFLASLSVRDFYKFEADYDLVFTT
                     TPLKSSMLQFMIEPIMTYQQQISLRYRVLSDLGITKVDRAMDELLTIIRKYANITNPV
                     SLREELQYFLIKEDGSTPLDNFNVLPSLTYYLRPSYVQIVEEEMSWERAVEVACRPLL
                     EHQIIDSRFIADCLDQIRQPGYAGYLGMKTCIPHTTVDKGVISDGVSILVCKKPIRFP
                     NGEDVSLILPLSFFDLTKHLRAINQIADIAKDDSLIEQLLIADDEKTVYQLLRQRS"
     gene            2155..2775
                     /locus_tag="ACF3MF_001981"
     CDS             2155..2775
                     /locus_tag="ACF3MF_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HFE3927947.1"
                     /translation="MRLADYPKLTVIMRGYTFDQADAILQAMQEFDHQFAVEMTMNTK
                     GALENIHELNQRYGDTTYIGAGTVRTLEQAQACYEAGAKFLLGPHMFTKEMLSYANKK
                     GLLAVPAAMTPSEVDRMFKEGADIVKVFPAAVVTPRFFKDIQAPLGKLPLMGVGGISK
                     ENAKEFFEQGASYLGLGSGMFNKQDIEELNVKNLARSMKELIEAIK"
     gene            2787..3245
                     /locus_tag="ACF3MF_001982"
     CDS             2787..3245
                     /locus_tag="ACF3MF_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFE3927948.1"
                     /translation="MELYLNEELVFRNVQAKTDSEVLAFLASEMYKKNYVKEEYIQAI
                     QEREKEYPTGLPSTPPGIAIPHANYEMVNKTTLAIATLKDPVLFHNMEDNNEQLPIQI
                     VIMMAIGEPHGQVEMLQKIVGIIQDEPLRQEMIRAGNDTELLELLKKAVF"
     gene            3264..3542
                     /locus_tag="ACF3MF_001983"
     CDS             3264..3542
                     /locus_tag="ACF3MF_001983"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFE3927949.1"
                     /translation="MKRILVACGNGIATSTVVATKVREYLQQHGIDVSTTQTKLMEVP
                     GKVQDYDLLVTTGQFDGQTGGVPVIKGMPILTGIGADQTMEEILNLLK"
     gene            3567..4934
                     /locus_tag="ACF3MF_001984"
     CDS             3567..4934
                     /locus_tag="ACF3MF_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002386123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HFE3927950.1"
                     /translation="MKIIMNVFNFFIDAGPTVMLPVIITIIGLIFGLKISRAFKSGLT
                     LGIGFAGIKLILDFMTTNVGPAAKAMVDRTGVKLDALDVGWGSIAAVTWASPIIPILI
                     FAILLVNIVLLILKRTHTLDVDIWNYHHMAIVGVIVYFVTKNVFLGVGASVVMAIATF
                     KISDWSQPMVESFFGIPGVSLPTVSALSSLVIAWPLNWLLDRIPLFRKSKFTIKDAQK
                     YLGFFGDSMIMGLVIGMVIGVLAGYDIKAVLQLGVSMSAVLVLIPKMTSLFMEGLMPI
                     SDAAQKWSQKKFKGTRLFIGLDAAVVVGNPDVITTALIIIPLTIALALVLPGNRVLPF
                     ADLAVVPFRVAMVVALTRGNLLKNIIIGLVVTASLLWCGSATAPMLTAIAKSVGINLG
                     TSSMLISSFAATSMIQSYLVFIAFAYKPIIGIPVLLLAFAGAWYYFDGIKKVNHEMDE
                     PLKAQ"
     gene            4949..6094
                     /gene="dgoD"
                     /locus_tag="ACF3MF_001985"
     CDS             4949..6094
                     /gene="dgoD"
                     /locus_tag="ACF3MF_001985"
                     /EC_number="4.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008869 - galactonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009063 - amino acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactonate dehydratase"
                     /protein_id="HFE3927951.1"
                     /translation="MKISDVTVYKVKPRWIFVKISTDEGIEGWGEMISGTKTETVVAG
                     AYEIGNRLIGRNPFEIERLFQEMHRSFFRGGPINGTIVSGLEMALWDIKGKAFNVPVY
                     ELLGGAARDKIKVYSWIGGDRPSEVAEQAQDRFDRGFTAVKMNATEELHYIDSYQKVD
                     EVVERVASIRERFGDAMDIGVDFHGRVHKPMAKVLAKALEPFHPMFLEEVVLPENEEH
                     FKEVADSVAVPLATGERLYTRWQFKNLFKQGTVDIIQPDVALCGGILETRKIAAMAEA
                     YDMAVAPHAPYGPVALAATLQVDSCTPNVFIQEQSLGIHYNKGFDLLDFVKNKEVFQY
                     KDGYVDLPSKPGLGLEMDEDKIKEIAQEGLIWTNPQWKNYDGTIAEW"
     gene            6121..6612
                     /locus_tag="ACF3MF_001986"
     CDS             6121..6612
                     /locus_tag="ACF3MF_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927952.1"
                     /translation="MAEALMITVFLGLLIILQIIDQKKIIVFAQSSPVRKSLSILLTV
                     AILLIFWPEHLTDQIKLVAFASVILINGFLKEGLAKDSVVRFGVLNGNFNRYPQVQVE
                     KLGDDKSFISFYKSKNNSFSMIFDKDQTEMMDVFQELDIHSKITLDQSSEEKRAVVKK
                     DNE"
     gene            7055..8254
                     /locus_tag="ACF3MF_001987"
     CDS             7055..8254
                     /locus_tag="ACF3MF_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFE3927953.1"
                     /translation="MRDQTSGKMIRFYYTSLHFLYWMMFCSVYGFATLFLIYFKIDPA
                     KIGGILALVNIVSTVLQPFVSQVIIKKRKIPLITVLKTMIAGLGVILLAGVLIPNLPI
                     ITYILGGILVVSMQSFLNALAFEYSNTGYRINFGFSRAGGSFSYAVTSFLLGQLLAIY
                     SAAILPILVIVEAVIFFVILHLLPDVKNQEVFPMTKEQDRSVSLRKKYPFLILLFLGF
                     SFLFTFHTMINSFLAQIFENIHGGSKEVGIALMIAALCELPGMIFFEQLVKKKSSKFW
                     LSVASISFAVRGFMMLLASSILMMEMTHLLQAFSFALFIPASAYLFNQFLADDDRVFG
                     QTMIIIATTLGGVIGNVLGGSLLQHFGVWEMLIFGTGFAVLGALLTILGIRKIPKTGN
                     DSDSLVE"
     gene            complement(8749..9507)
                     /locus_tag="ACF3MF_001988"
     CDS             complement(8749..9507)
                     /locus_tag="ACF3MF_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFE3927954.1"
                     /translation="MDTKLSESEKYLWDFIQSHILEIPSYSIVKLSEYANVSTATVVR
                     TMKKKGYEGFTSFKHSLKEKENTNINFAALDKVDEGIKTAILKNEQEVIRTINMVESG
                     NIEDAIQRIKAARRIMIFARGFSELIAQEMMVKFQLTGKYCEMHTDPNIIKNISRKLS
                     KDDIVIFVSLNGETKELTTAAENCYKAEIGTILLTANRHSSLMEHIEIPFVGFKSEGS
                     FFPDYEVRSRLPLSILARILLDSYALRTSGFTQH"
     gene            9675..10610
                     /gene="pfkB"
                     /locus_tag="ACF3MF_001989"
     CDS             9675..10610
                     /gene="pfkB"
                     /locus_tag="ACF3MF_001989"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HFE3927955.1"
                     /translation="MSVYTCTLNLAIDLFIETDEMKPSQVNRTNDDDIQANGKGVNVS
                     LIMKQLGIDSTALGFKAGFTGNYIEDYLHQKDISTDFISVPGMTRINVFTQVNKTNEE
                     FKLVNKGPEIPQEQIKTFLNQIQKLQADDYLCVSGSLPRGVSPEILIDISRICFENKV
                     HLIIDSSYPEIIDCLPYQPFLLKPNEEELQSWYNVELSDREGYIHYAERLIADGAKNV
                     LLSLGGEGGIFLNKDIVYSGNSPKGKVVNTACAGDTLLGTFLAGYLKGEQVDINLKKS
                     LAAGSSTAFRKGLTDFSDVAELEKQIEIKEGASKK"
     gene            10607..12052
                     /locus_tag="ACF3MF_001990"
     CDS             10607..12052
                     /locus_tag="ACF3MF_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFE3927956.1"
                     /translation="MTTYKIVAATGCPTGIAHTYMAQEALEQAAKRKGVSIKVETHGQ
                     VGIENELTPEEIKNADAVIIAADKDVQAERFAGKRVIDVPVSKGIKDADQLIEDALAG
                     KGSITAENKTVDAAGEKAEMGVAAGIGHSIYKNLMNGVSHMLPFVVAGGVIIAISFAI
                     WGVYSFDPNDPTYNPTAAMLKGVGDAAMGMMVPILAAYIAEGIAKRPGLVVGFVGGLL
                     ANSGGAGFLGGIFAGFLAGYFILLLQKVMKGLPKQLDGLKAIFLYPVIGVLFVGVVMS
                     LLANPMEAVNQGMMNFLAGFQNSNPLILGIIVGCMSAFDMGGPVNKAAYVTGTALLAQ
                     GNHTFMAGVSAACIAPPLITGFAALFFGKYFDTNDRNAGLVNFILGSTHITEGAIPFA
                     AKDPLRVLPTMMLGSSIAAVLTYMFGVQVPAPHGGFLVLPVVTGKVAWVGSILLGSIV
                     GGVILGLIQKRSVEKREAEAAAVEMKEATNN"
     gene            12080..12535
                     /locus_tag="ACF3MF_001991"
     CDS             12080..12535
                     /locus_tag="ACF3MF_001991"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose PTS transporter subunit IIA"
                     /protein_id="HFE3927957.1"
                     /translation="MTLIKTNKVFMNKNFTTQDEVMNFLADQSIVLSISEDRDAVYEK
                     LMEREEESTTGMMDGFAIPHAKDASIKDADIVIVRLNGKVDWKSLDGEGTDFVIALFI
                     PDSEAGTTHLKFLSQVARLLMHKDVTEGLKQAQSAEEIAELLNQKLEEN"
     gene            12554..13528
                     /gene="lacD"
                     /locus_tag="ACF3MF_001992"
     CDS             12554..13528
                     /gene="lacD"
                     /locus_tag="ACF3MF_001992"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HFE3927958.1"
                     /translation="MPLTEKKKTYIRQLSNESGIISALAIDQRGALKKMIGKFQNKSA
                     TDEQIINFKKIISSELTPYASAILLDPEYGLPAAEVRDKNAGLLLAYEKTGYDASTPG
                     RLPDILSIWSVKRLKEQGADACKFLLYYDVDESDDINDQKKAFMERIGSECVAEDLPF
                     FLELVSYDANDPDTSSKEYALKKPHKVNEMMKEFSKPRYGVDVLKVEVPVNMNYVDGY
                     TKNEVAYTKEEAAAYFKEQSETTNLPFIFLSAGVTAELFQETLKFAKEAGSTFNGVLC
                     GRATWANGVEPFVTKGEYAAKEWMQTQGRKNIEELNNVLKETATAIKL"
     gene            complement(13639..14200)
                     /locus_tag="ACF3MF_001993"
                     /pseudo
     CDS             complement(13639..14200)
                     /locus_tag="ACF3MF_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364878.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
     gene            14344..14958
                     /locus_tag="ACF3MF_001994"
     CDS             14344..14958
                     /locus_tag="ACF3MF_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFE3927959.1"
                     /translation="MELAFKQLEKKDYKKAIQFAIKGMHFDWYTKNKLLLNLYGRYFW
                     YLELNRATQIIALYADDELAGVLLADIKGKSKKHHSFSQKLYVKLFDFLQNAFVKDSK
                     GGYDDTNDELLSDYLKKHSPDGEIVFLAANPDLKIKGIGSKLLKEFERREQGKEVFLF
                     TDSGCTYQFYERRGFERKKEKDNVMKILNKEVDLRCMLYSKIIQ"
     gene            15199..15582
                     /locus_tag="ACF3MF_001995"
     CDS             15199..15582
                     /locus_tag="ACF3MF_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFE3927960.1"
                     /translation="MPKYKEIALALKERIVEGKYQEGSKLPEQESLAREFKTSRVTIR
                     KAIQLLIDEGLLYTRRGSGTFIRSNIRQDNENVTQVNNVFGTSSQENTNVTSKIIRFD
                     VRFPTDYERRLSATYFRSPSCKSWV"
     gene            15945..16454
                     /locus_tag="ACF3MF_001996"
     CDS             15945..16454
                     /locus_tag="ACF3MF_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HFE3927961.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILEVFAEAELYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
     gene            16554..17204
                     /locus_tag="ACF3MF_001997"
     CDS             16554..17204
                     /locus_tag="ACF3MF_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927962.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEVRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNTNHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            17655..18593
                     /locus_tag="ACF3MF_001998"
     CDS             17655..18593
                     /locus_tag="ACF3MF_001998"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFE3927963.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
     gene            18606..19658
                     /locus_tag="ACF3MF_001999"
     CDS             18606..19658
                     /locus_tag="ACF3MF_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFE3927964.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            19698..>20157
                     /locus_tag="ACF3MF_002000"
     CDS             19698..>20157
                     /locus_tag="ACF3MF_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HFE3927965.1"
                     /translation="MRCQQHLTYVFLPKYGFYFLLLGVISDLSTPYILGLFYPKLNQM
                     TTVISVFGDVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFVGTSKTLAILAVATVGLY
                     GIGDCIFTGLFSINTNESSWNLSTWIHNTGSGLGYAGFLLFPLLLVLLYRQ"
BASE COUNT         6383 a         3202 c         4267 g         6305 t
ORIGIN      
        1 gtgacaaaac attaaaccaa gtgtgacaaa aaacgtgatg aaagctttcc ggaaacgtat
       61 gtgaacaagt atataatgat tttgtcagga ggatagtcaa aatgaataaa cgaattcgtg
      121 aaatactcaa actgattatt aaaaaccctg aaatgaaact ttccacttta acaagtgaac
      181 ttgatttgac acgtcgtcaa atcaattacg cgatcaatca atttaatgaa gaattgaaaa
      241 caaagaacat tccgttaatt cagagaagtc attctggaaa tattacggta ccaatcgagg
      301 ttatccaaat gatatcacag cctgattacg acataggtga tgatcaggaa cttgtcgttc
      361 tcactgatag tgaaagacaa gcattgatag tgatgactct gatcgctaat atcgattaca
      421 tcagtctgga tcatttggta gatgcggttg atgttagtaa gacgactgtt atggaagata
      481 tcaaacgaac ggaaccgttc atcagaaatt atagtctgac aattcgatat aatcggatga
      541 atggttacca attggttggt tcggaacacc gtatcttaca gctgttatcg gatctagtaa
      601 aacggtttcc gatttttcgc cgagaaatga ttcgcagaaa attggcacaa gatgtttctg
      661 aagaagaaat cgtccatttg atccataaca tggaacaaat gttgcatctt agttattctg
      721 atgagtcggt agactatttg cagacatcag cgagattttt agtaagccgt gggatcaaga
      781 tgtcagataa gcacgcgttt tttcccgatg atgtgacgga tactcctgaa ttccgaatgc
      841 tgatgatctt ggtacatgaa acaggttgga gtctatccaa aagttatatg gagtggttca
      901 cgttattatt tttaacttcc aatatttttg agagcaaaac tactcaaaat tatgattcgg
      961 atcaagaatt gcgaaaattg atcagccaaa tggttgaaaa tttccaaaat caaacgttga
     1021 ttttgatcga tgaccgagaa gactttgaac gtaggatact gagtcatctg cgtccagcct
     1081 gttttcgaat acgctataac ttgagtttag gagtttattc aatagatagt ctgatcaagg
     1141 atagtaatca tgcgattttg attgatttga tgaaagaatt gattattcct attgagaatt
     1201 ggctaaataa ggcctttcca aatgatgaat tagatctttt atcctattac tttggctatc
     1261 aattaagtaa tcataataaa ttgaataagc aacgacaaag ggctgtagtt gtttgtacta
     1321 atggtgtcat ggtctcaaag ttagtacgag ccaatatgga aaaacttttt ccagagatcc
     1381 attttttagc ttccctatct gtgcgtgatt tctacaaatt tgaagctgat tatgatctgg
     1441 tctttactac gacgccacta aaaagttcta tgctgcagtt tatgatcgag ccaatcatga
     1501 catatcagca acaaatcagt ttacgatatc gagttttgag tgatttagga attactaagg
     1561 ttgatcgagc aatggatgaa ttgttaacaa tcattaggaa atatgcaaat atcaccaatc
     1621 cagtttcgtt gcgagaagaa ctgcagtact ttttgatcaa ggaagatgga agcacgccgc
     1681 tggacaactt caatgtattg ccttcattga cttattactt gcggccgagt tatgtacaaa
     1741 tcgttgaaga agagatgtct tgggaacgag cagtggaggt ggcttgccga ccgttattgg
     1801 aacatcaaat cattgactcg cgttttatcg ctgattgctt ggatcaaatc agacaaccgg
     1861 gatatgcagg ttacttggga atgaagactt gcattcccca tacaacggtc gataaaggtg
     1921 taatcagtga cggtgtcagc attttagttt gtaaaaagcc gatacgattt cctaatggtg
     1981 aagatgtcag cttgattttg ccgctttcat tttttgattt aacgaagcat ctgcgagcca
     2041 tcaatcaaat cgctgatatc gccaaagatg attcattgat tgagcagtta ttgattgctg
     2101 atgacgaaaa gacagtttat caactattaa gacaaagatc ttaaggagga aaacatgaga
     2161 ctagcagatt atcctaaatt gacagtgatc atgcgtggtt atacttttga tcaggcagat
     2221 gctattttac aagcaatgca ggaatttgac catcaatttg ccgtagagat gacaatgaac
     2281 acaaaaggag ctcttgaaaa tatacatgaa ctaaatcaac gttatggtga cacgacttat
     2341 atcggcgctg ggacggtaag gacattagaa caagcccaag cctgctatga ggctggtgca
     2401 aaatttttat taggaccaca tatgttcaca aaagaaatgt tgtcttacgc caataagaaa
     2461 ggattattgg cggtacctgc cgcaatgact ccttcagaag tcgaccgtat gtttaaagaa
     2521 ggagctgata ttgtaaaagt atttcctgca gcggttgtta ctccacgttt tttcaaggat
     2581 attcaagcac ctttaggtaa gttaccacta atgggggttg gtggaatcag taaggagaat
     2641 gcgaaagagt tttttgaaca aggtgctagc tatttaggtc ttggttccgg tatgttcaac
     2701 aagcaagaca tcgaagagct aaatgttaaa aacttagcac gttcgatgaa agaattaatt
     2761 gaggctatta aataggagtg aggactttgg aactttattt gaatgaggaa ctcgtttttc
     2821 gaaatgttca agcaaaaaca gatagtgaag tcttagcgtt tttagcaagc gagatgtaca
     2881 aaaaaaacta cgtgaaggag gaatatattc aagcaatcca agaacgggaa aaagaatacc
     2941 ctactggatt accatcaaca ccaccaggaa tcgcaattcc ccatgcaaac tatgaaatgg
     3001 tcaataaaac aactttagca attgcgactc ttaaagatcc ggtcctattt cataatatgg
     3061 aagataacaa tgagcagtta ccaatccaaa ttgtgatcat gatggcgatt ggggaaccac
     3121 atgggcaagt tgaaatgtta caaaaaattg ttggaatcat acaagatgag ccactgcggc
     3181 aagaaatgat cagagcaggc aatgatactg aattattaga actattaaag aaagcggttt
     3241 tttaatataa ggaggaaatc ataatgaaac gaattttagt agcatgcgga aatggtatcg
     3301 ccacttcaac agtagtagca acaaaagtta gagagtattt gcaacaacat ggcattgatg
     3361 tttcaacgac tcaaacaaaa ttgatggaag ttccaggaaa agttcaagac tatgatctat
     3421 tggtgacgac tggtcaattt gatggtcaaa caggtggtgt accagtaatc aaagggatgc
     3481 cgattttaac aggtatcggt gccgatcaga caatggaaga gattttgaac ttactgaaat
     3541 aatagctgat caaaggagct gaaaaaatga aaatcattat gaacgtcttt aacttcttta
     3601 ttgatgctgg accaacagtt atgttgccag tcatcatcac gattattggt ttgatttttg
     3661 ggttaaagat ttctcgtgct tttaaatcag gtttgacatt aggtatcggt tttgccggga
     3721 tcaagttgat attggacttt atgacgacca atgttggacc agctgccaag gcgatggttg
     3781 atcgaactgg tgttaaacta gatgctttgg atgttggctg gggttcgatt gcggctgtta
     3841 cttgggcatc gccaatcatt ccaatcttga tttttgccat tctattggtc aatatcgttt
     3901 tgctgatttt gaaacgtaca catacgctgg atgttgatat ctggaactat caccatatgg
     3961 caatcgttgg tgttatagtg tattttgtga ctaagaatgt cttcttaggt gtaggtgcat
     4021 cagtagtgat ggcaattgcg acttttaaga tttcagactg gtcgcaaccg atggtagaaa
     4081 gtttcttcgg aatccctggt gtttctttac caactgtttc tgcgctttca tcactggtta
     4141 ttgcttggcc gttaaattgg ctgctggatc gtatcccgtt attcagaaaa tcaaaattca
     4201 ccatcaaaga tgcacaaaaa tatttgggat tttttggtga ttctatgatc atggggttag
     4261 ttattgggat ggtgattggt gttttagccg gctatgatat caaagcggtt ttacaattag
     4321 gtgtcagcat gtcagctgtt ttggttttga ttcctaagat gacttcatta tttatggaag
     4381 gattgatgcc aatttcagat gctgcacaaa aatggtcaca aaaaaaattc aaaggtacac
     4441 gtttatttat cggattggat gctgcagttg ttgtaggtaa tccagatgtt atcacaacag
     4501 cattgatcat tattccacta acgattgcat tagctttagt attgccagga aaccgtgtgt
     4561 taccattcgc agatttagcg gttgttcctt tccgcgtggc aatggtcgtt gccttgactc
     4621 gtggtaattt attaaaaaat atcattattg gcttagttgt gacagcttca ttgctatggt
     4681 gtgggtcagc tactgcgcca atgctgacag caattgccaa atcggttggt attaacttag
     4741 gaacttcttc aatgttaatc tcatcatttg ctgcgacttc catgatccaa agttatttgg
     4801 tatttatcgc atttgcttac aaaccaatca tcggtattcc agtgttgtta ttagcctttg
     4861 cgggcgcatg gtattacttc gatggtatca aaaaagttaa tcatgaaatg gatgaaccat
     4921 tgaaggcaca atagtaggag ggtttaaatt gaaaatttca gatgtcacag tgtataaagt
     4981 aaaaccaaga tggatttttg ttaagatctc gactgacgaa ggaatcgaag gctggggaga
     5041 aatgatctca ggaactaaaa cagaaacggt tgttgctgga gcttatgaga taggaaaccg
     5101 gctgattgga cgtaatccgt ttgaaatcga gcgcctcttc caagaaatgc atcgatcttt
     5161 cttccgaggc ggtcctatta atggaaccat cgtttcgggt ttagaaatgg ctctgtggga
     5221 tatcaaagga aaagcgttta atgttccggt ttatgaatta ttgggcggtg cagcacgtga
     5281 taaaatcaag gtttattctt ggattggtgg agatcgacca agtgaagttg cagaacaagc
     5341 acaagatcgg tttgatcggg gctttacggc cgtcaagatg aacgcgacag aagagctgca
     5401 ttatatcgat tcctaccaaa aagttgatga agtggtggaa cgagttgcgt ctattcgcga
     5461 acgttttggt gatgcaatgg atattggtgt tgattttcat ggacgggtcc ataaaccgat
     5521 ggcaaaagtg ctagcaaaag ctttggagcc attccatcca atgtttttgg aagaagtcgt
     5581 tttacctgaa aatgaagaac actttaaaga agtagctgat tctgtggctg taccattagc
     5641 tactggtgaa cgcttgtaca ctcgttggca attcaagaac ctctttaaac aaggtactgt
     5701 tgatattatc caaccagatg tggctctttg tgggggaatc ttggaaaccc gtaaaatcgc
     5761 agcgatggcg gaagcttacg acatggctgt tgcgcctcat gcgccatatg gtcctgttgc
     5821 actagcagca actctgcaag tagactcatg tacgccaaac gtctttatcc aagaacaaag
     5881 cttagggatc cactataaca aaggttttga tctgttagat tttgtgaaga acaaagaagt
     5941 tttccaatat aaagacggct acgtagatct accttcaaaa ccaggtctgg gcttggaaat
     6001 ggatgaagac aaaatcaaag aaattgcaca agaaggtttg atttggacca atccgcaatg
     6061 gaaaaattat gacggtacga tcgctgagtg gtgataaatg aaaataaagg atgatgaaag
     6121 atggcagaag cacttatgat cacagttttt ttaggactgc tgattatttt gcaaataatc
     6181 gatcaaaaga aaattatcgt gtttgctcag agtagtcctg taaggaagag tttgagtatt
     6241 ttactgacag tcgccatcct gttgattttc tggccggaac atctgactga tcagattaaa
     6301 ctggttgctt ttgcttctgt cattttgatc aatggttttt tgaaggaggg tctagcaaaa
     6361 gattctgttg ttagatttgg agtattgaac ggtaacttta atcgatatcc tcaagtccaa
     6421 gtagaaaaac taggtgacga taaatcattt atttcatttt acaaaagcaa gaataattct
     6481 ttttcaatga tttttgataa agatcaaact gaaatgatgg atgtctttca agaacttgat
     6541 atccattcca aaattacttt agatcaaagt tcggaagaaa aaagagcagt tgtaaaaaaa
     6601 gataatgaat gattctacta ccgaaattat gatttcttta tcacgaataa tgaaacttgt
     6661 tttaatgaat catattgatt gaagtataca atgtatatta agttttggaa agaaatatat
     6721 tggtacaaga tatagcagga atcgattact cgatccctgc tttttttaac ttcctttgca
     6781 gcaaaaaaag ctcgtaatct aagagatgat ggatagtttt tagaatatat atattttctt
     6841 caattccaga aaaaaatgac caagctagta tgctaaaaaa gtacgatgct tctatgatct
     6901 tttttccgtc tttattaaca gatgttttaa ttgatcaacg catattgtaa tctaccctaa
     6961 tttccatagt tcttcaccac ttttaaaaat agtaaaaccc ctacaagtat gctatagtaa
     7021 attgctaaag aaaaaccaat aaggtgggag atgtgtgcgc gatcaaacaa gcggaaaaat
     7081 gattcgtttt tattatacaa gtttgcattt tctttattgg atgatgtttt gttctgtcta
     7141 tgggtttgcg acattgtttt tgatttattt caagattgat ccagctaaaa tcggagggat
     7201 cttagcattg gtcaatattg tttcaacggt gcttcagcct tttgtcagtc aagtgatcat
     7261 caagaaaaga aagatcccac tgatcaccgt gctgaagacg atgatagcag gattaggagt
     7321 gattctctta gctggggtat tgattccgaa tttgccgatc attacttata tcttgggtgg
     7381 gattttagta gtttctatgc aatcatttct caatgcgctg gcatttgagt attcaaatac
     7441 cggctacagg atcaactttg gcttttcaag agctggtggt tcattttctt atgctgtaac
     7501 ttctttttta ctgggacagc tgttagcgat ttattctgcc gcgattttgc caatcttggt
     7561 tatagttgaa gcagtgatat ttttcgttat tttgcatctg ctgccggatg taaaaaatca
     7621 agaagttttt cctatgacaa aagaacagga tcgctcagtt tctttgagaa aaaaatatcc
     7681 tttcctgatt ttgttatttt taggtttcag ttttcttttt actttccaca ccatgatcaa
     7741 cagctttttg gcacagatct ttgaaaatat ccacggcggc agtaaagaag ttggcatcgc
     7801 attgatgatc gccgctttat gcgaattacc gggaatgatc ttttttgaac agcttgtcaa
     7861 aaagaaatcc agcaaatttt ggctgtctgt tgccagtatt tcatttgctg tcagaggatt
     7921 catgatgctg ctggccagtt cgatcctgat gatggaaatg acgcatctcc tacaagcctt
     7981 cagtttcgct ttgtttattc cagcttcggc ttatttgttc aatcaatttc tggcggatga
     8041 tgatcgtgta tttggacaaa cgatgatcat catcgccaca actcttggtg gggtgatagg
     8101 aaatgtcttg ggcggcagtc tgctgcagca tttcggtgta tgggagatgc tgattttcgg
     8161 tactggtttt gcggtgctag gtgctttatt aactattttg ggcattcgaa aaataccgaa
     8221 gacaggaaac gatagtgatt ctcttgttga gtagcataaa aatacttaga tactagtttt
     8281 atataaataa catatagtga ttattggcgt aattacaaaa aacgagaata acttaagtaa
     8341 gcatttctaa ataattgaga aacctcatct aaaaagataa gaaaatatcc ctaataaaac
     8401 ttctgtaaca ttttagataa ctgattgtaa tctgaataat aaactataag gagacggtta
     8461 gacggtctcc tttttttgcg tattataatt ctagaattgt tggaaattga taataattaa
     8521 caagaaatat tagacaggaa cttcgaactg cttatcacat tcttattatt atatatttgc
     8581 gtaagtagtc ctggtagtct caatgcacta ttctatcttg aaactaagaa gttatagaag
     8641 gagcaatgat agaaagcacg agaatacaaa tagcgattaa atatttttct agacaacctt
     8701 agttaattca cacagatata ttttaggtac agtcttacag atatagagtt agtgctgtgt
     8761 gaatcctgat gttcgcagtg cataggagtc aagtaagatt ctagccagta tagaaagtgg
     8821 aagtctggag cgtacctcat aatctgggaa gaaggagcct tctgatttaa agccaacaaa
     8881 aggaatctcg atatgttcca tcaaacttga atgacgatta gcagtaagca aaattgtccc
     8941 gatctcagct ttataacagt tttcagctgc ggtagtcaat tcctttgttt caccgtttag
     9001 tgaaacaaag atcacgatgt catctttgga taattttcta ctaatgtttt ttatgatatt
     9061 gggatcagta tgcatctcac aatatttacc ggtaagttga aatttgacca tcatttcctg
     9121 agcaatcaat tctgaaaaac ctcgggcaaa aatcatgatt cttctagcag ccttgattcg
     9181 ttgaatagca tcttcaatat tcccgctttc taccatattg atggtgcgga ttacctcttg
     9241 ctcattttta agaatagcag tctttattcc ttcatcaact ttatcaagag cggcaaaatt
     9301 gatatttgta ttttcttttt cttttaacga atgtttaaaa gacgtaaacc cctcatatcc
     9361 ttttttcttc atagtacgaa cgacggttgc tgttgaaacg ttggcatatt cacttagttt
     9421 tacaatggaa taggagggga tttcgagtat gtgactttga ataaaatccc agagatattt
     9481 ctccgattca cttaattttg tatccatatt ttgcctccga ttagttagga taattctatt
     9541 gtaaagcggg agtttccttt acttcaagtt tatttaatat attttgtaaa agttttcaat
     9601 gaatttagtc atttatgaaa acatttacat tcgatcttga tacataatga atatgtaaga
     9661 aaggaggagc gtaaatgtca gtttatacat gtactttaaa cttggcaatc gaccttttta
     9721 tcgaaacaga tgaaatgaaa ccatcccaag tcaatcgaac aaacgatgat gatatacaag
     9781 ctaatggaaa aggtgtgaat gtttcattga tcatgaagca attaggtatc gatagtacag
     9841 ctttaggatt taaagcaggt tttaccggga attatattga ggattatttg catcaaaaag
     9901 atattagcac tgattttatt agcgtaccgg gaatgactag aatcaacgtt tttacacaag
     9961 ttaataaaac caatgaagaa ttcaaattgg ttaataaagg acctgagatt cctcaggaac
    10021 aaatcaaaac ttttctaaat caaatacaaa agctgcaagc tgacgattat ttgtgtgttt
    10081 ctggcagttt gccgcgaggg gtctcacccg aaattcttat tgatatcagt cgtatttgtt
    10141 ttgaaaataa ggtccatctg attattgatt caagctatcc ggaaataatt gattgtctgc
    10201 cgtatcagcc gttcttatta aaaccaaacg aggaggaatt gcaatcttgg tataatgtcg
    10261 agcttagtga tcgtgaagga tatattcatt atgctgaacg cttgattgcc gatggagcga
    10321 aaaatgttct cctttctcta ggaggagagg gaggaatatt tttaaataag gatatcgttt
    10381 attctgggaa ttctcctaaa ggtaaagtag tcaatacagc gtgtgctggt gacactttgt
    10441 tgggaacatt tcttgcagga tatttaaaag gtgaacaggt agatattaat ttgaagaaaa
    10501 gtttagcagc tggaagttca accgcttttc gtaaaggatt aacagatttt tcggatgttg
    10561 cagagttgga aaaacaaatc gaaatcaaag agggagcgag taaaaaatga caacttacaa
    10621 aattgttgcc gcaacaggat gtccaacagg aattgcccac acttatatgg ctcaagaagc
    10681 attggagcag gcagctaagc gcaaaggggt atctatcaaa gttgaaaccc atggtcaagt
    10741 agggatagag aatgaattaa caccagaaga aataaaaaac gctgacgctg taatcattgc
    10801 agctgacaaa gatgttcaag cagaacgttt cgcaggtaag cgtgtaatcg atgtgcctgt
    10861 cagcaagggg attaaagatg ctgaccaatt gatcgaagat gcgttggctg gtaaaggttc
    10921 aatcactgca gaaaacaaaa cagttgacgc tgctggtgag aaagcggaga tgggggttgc
    10981 agcaggcatt ggtcacagta tttataaaaa tctcatgaac ggtgtttctc atatgctgcc
    11041 gtttgtagtg gcaggtgggg taattattgc aatttcgttt gccatctggg gtgtgtactc
    11101 ttttgatccc aatgatccta cttacaatcc gactgccgct atgttaaagg gtgttggtga
    11161 tgcggcaatg ggaatgatgg ttcctatttt agcagcttat atcgctgaag gaatcgctaa
    11221 acgtcctggt ttggttgttg ggtttgttgg cggactgtta gccaattctg gcggagccgg
    11281 tttcttaggc ggaatttttg caggtttctt agcaggctac tttatcttac tattgcaaaa
    11341 ggtcatgaaa ggcttgccta aacaattgga tggtctgaag gcgatcttct tatatccggt
    11401 gatcggtgtc ttgtttgttg gtgtagtcat gtctttatta gcaaatccaa tggaagcagt
    11461 caaccaagga atgatgaatt tcttggcagg attccaaaat tctaatccat taattttagg
    11521 gattatcgtt ggctgtatgt cagcatttga tatgggaggt ccagtcaata aagcggctta
    11581 tgttacaggg actgcgttgt tggcacaagg taaccataca tttatggcag gggtttcggc
    11641 agcttgtatc gcgcccccat tgattactgg atttgccgca ctgttttttg gaaaatattt
    11701 cgacacgaat gatcgcaacg ctggtttagt caactttatc ttgggctcaa cgcacattac
    11761 cgaaggagca attccatttg cggctaaaga tccgctgcgt gttctgccaa ctatgatgct
    11821 aggttcatca attgctgctg tactgacata tatgtttggt gtccaagttc ccgcacctca
    11881 tggaggtttt ctagtattac ctgttgttac tggtaaggtt gcatgggtag ggtcgatttt
    11941 acttggttca atcgttggcg gagtaatttt agggttgatc caaaaacgta gtgtagaaaa
    12001 acgtgaagca gaagcagctg ctgttgaaat gaaagaagca accaacaact aaaggttatt
    12061 ctagaaagaa ggatttcaaa tgactttgat caaaacaaat aaagttttta tgaataaaaa
    12121 ttttacgacg caagatgagg taatgaactt ccttgcagat cagtcaattg tcttgagcat
    12181 tagtgaagac cgagatgcag tttacgaaaa attgatggaa agagaagaag aaagcacgac
    12241 tggtatgatg gatggttttg ccatccctca tgccaaagat gctagtatca aggatgccga
    12301 tattgtgatt gttcggttaa acggtaaggt cgattggaaa agtttagatg gagaaggaac
    12361 ggattttgta atcgctctgt ttattccaga ttcagaggct ggaacaaccc atctaaaatt
    12421 tttatctcag gtagccagac ttttgatgca caaagatgtg acagaaggtc tgaaacaagc
    12481 ccagtctgct gaagaaatag ctgaactttt aaaccaaaaa ttagaagaaa actaaaaagg
    12541 aagtagtgaa atcatgcctt taacagaaaa aaagaaaact tatattcgtc aactaagtaa
    12601 tgaaagtggc atcatcagtg cgttagcaat cgatcaacgt ggtgccttga aaaaaatgat
    12661 cggtaaattt caaaataaat cagcaaccga tgaacaaatc atcaatttca aaaaaatcat
    12721 ttcttctgaa ttgactccat atgcttcagc aatcttatta gatccagaat atgggttgcc
    12781 ggcagccgaa gttcgcgata aaaatgctgg tctgttgttg gcctatgaaa aaactggtta
    12841 cgatgcttca actccaggac gtttaccgga tattttatct atttggtctg taaaacgtct
    12901 aaaggagcaa ggggccgatg cttgtaagtt cttgttatac tacgatgtag atgaatctga
    12961 tgacatcaat gaccaaaaga aggcgtttat ggagcggatt ggttctgaat gtgttgctga
    13021 agatttgcca tttttcttag aattggtttc ttatgatgcc aacgatcctg atacttcttc
    13081 gaaggaatat gccttgaaaa aaccgcataa agtaaatgaa atgatgaagg aattttctaa
    13141 gcctcgctat ggagttgacg ttttgaaagt ggaagttcct gttaatatga actatgtgga
    13201 tggttacact aaaaatgaag ttgcttatac caaagaagaa gctgctgctt atttcaaaga
    13261 acaatccgag actaccaacc tgccatttat tttcttgagc gcaggagtaa ctgctgaatt
    13321 gttccaagaa accttgaaat ttgcaaaaga ggctggctct acattcaatg gggtactctg
    13381 tgggcgcgca acttgggcga atggtgtaga accattcgtt actaaaggtg aatatgctgc
    13441 caaagaatgg atgcagacac aaggacgcaa gaacatcgaa gagctgaata atgttttgaa
    13501 agaaacagca acagctatta aattgtaaga aagctttaac tataacctta agtttgtaac
    13561 ctaatgattt ttaataatca atttgagctt ttaaataaag aattggaagc gtcccgacgc
    13621 ttcctttttc gtttgttttt aaggcatgat aggttctatg ttgtcgttca ataagcgcaa
    13681 gaaggtcagc atttttttct tagagtatgc aaaattgctt ttctacccaa tgatttaaaa
    13741 cggagaggca cccttggata tggtagatgg tgaagtaacg catttcttct gtgatcacgg
    13801 tttttttgtc ttcttgtagc cagattttta aataattttc ttcgatcaga ttatttaatc
    13861 tcttttgaaa ttggatatct ccgtggttga tgacgaataa cttgtatacg aacgtattcg
    13921 tatagacata gtcgatcaat tgagcgtata gatcctcgta gctatgtgtc gtatcgtagg
    13981 aaatgatttc atccaagtct tggaaaaagc tattttccag tttttcataa agatcataga
    14041 tatccgtata atgtgtataa aatgtcgaac ggtgaagatc agcagtttcg gtcagttcac
    14101 ggatggtgat gttttgaatt tttttatcta ctaataattt tgataatgct tctgctaacg
    14161 ctttttctgt ttttttgacg cggcgatcct cttttttcat tttgcagcct cctaatcaac
    14221 ataatcaagg aattgtgtcg gttatccgac aatttcaccg ctatctgaac atagataacc
    14281 gacaccttgt ctattataat ataagtatag catatcaata tttaaagaat aggagaataa
    14341 gtgatggaat tagcctttaa gcaactggaa aagaaagact acaaaaaagc cattcaattc
    14401 gcgattaaag gtatgcactt tgattggtat accaagaaca aactcctttt gaatctttat
    14461 ggaagatact tttggtatct agaattgaat cgcgcgacac aaatcattgc tttatatgcg
    14521 gatgatgagt tggcaggtgt tttattagca gacatcaaag gaaaatcaaa aaagcatcat
    14581 tcatttagtc aaaagttata tgttaaacta tttgatttct tacaaaatgc atttgtgaaa
    14641 gacagcaaag gcgggtatga cgacaccaat gacgaattgc tttcagacta tttaaaaaaa
    14701 cattccccag atggagaaat tgtcttttta gctgccaacc ctgatttaaa gatcaagggg
    14761 atcggtagta aattattaaa agaatttgaa cgccgagagc aaggaaaaga agtatttctg
    14821 ttcacggata gcggctgtac gtatcaattt tatgaacgac gcggtttcga acggaaaaaa
    14881 gaaaaagata acgtcatgaa gatccttaat aaagaagtag atctccgctg tatgttatat
    14941 agtaagatca ttcagtaatg ttttttacta tcagaaagca gaagtaccac gaaggtcaat
    15001 ggaaaaagcg agtaattgat ccatttagat gaagataggt gtagtctcaa agatattagc
    15061 tggcaaagat atccccagtt aaaaatagat ttctgtatcc aacaataaaa atatttttgt
    15121 atttattagt atatatactt tacaaaaatt tgtatatata ctaatttttt tgtaggatca
    15181 atgaaatgag gggaaaatat gccaaaatat aaagaaatag ccttggctct aaaagagagg
    15241 atcgttgagg gaaaatatca ggaaggttct aaattacctg agcaagaaag tctggctaga
    15301 gagtttaaaa caagccgtgt tactatccgc aaagctatac aactccttat tgatgaaggt
    15361 ttgttatata cgagacgtgg atctggtact tttatacgaa gcaatatcag acaggacaat
    15421 gagaatgtca ctcaagtaaa taatgtattt ggcacttcct cacaagaaaa tacaaatgtg
    15481 acaagtaaaa taatccgttt tgatgtccgg tttccgacag attatgaaag gcggctttct
    15541 gcaacctact tccgatcccc ttcctgcaaa tcatgggtat aaaaaatagg catattaagc
    15601 gggctaggag gagaaatatt cacatatcat tttttcattc cgcaagctgc gtcaagttat
    15661 ttggaatttg tagaacagat gagagaggta gaagcagcac tacaaactac ttttcaataa
    15721 gtaggaatta tagaaatttt actcaaaaaa tcttcattaa aaaatctgac taaataagtt
    15781 gagaaaacag aatatacttc aatatccagt gatttataaa tatcattcac tcatgatacc
    15841 cagctccgta tcataagtga tgcggttttt atcattgatc ctaaaaatct tagcaagaca
    15901 aaaagtacgt aagaaagtaa agactaaata cttcggagga acaaatgaat aacaatgata
    15961 ggttattgcg attgcgttat gcgattgatt tgaaagatac ggatttgatt aaagcttttg
    16021 agctaggcgg tgtaccactg actaaagaag aagctcaggc ggtactgacc aaagtacagg
    16081 ataagaacaa agataatgca gaaaataatg tgtatgaaaa aaccatcaac aaccaagttt
    16141 ttgacgcatt cctaaatggc ctgattctct tggcgcgtgg tccgcaaaaa gataagccga
    16201 tagtagacac gccgcaaaaa agcaaggaaa tcaaatatat caacaatgtg ttgctaaaaa
    16261 aattaaaaat cgccttgtct atgaccactg atgatatttt agaagttttt gctgaggcag
    16321 aactctatcc atcaaaaggc gaaatcgggg catttttgag aaaagaaggc caacgaaatt
    16381 ttaagccttg cggagataaa tatatgcgta attttctcaa ggggttagga atttataatc
    16441 ggagaaaagt ataaagaaat ttcatgagaa atcaaaacaa tggttgtttt gatgagagct
    16501 agtttttgta tgagattaaa atattatctt aatcgaggag ctggattggt tttatgaatg
    16561 atgaatataa gaatgatgaa gataagatgc tttttgaaga gatagagaat cgatgtaggc
    16621 tcaattttga gcttcgggga aagatgtctt taatacaaca aaaaaagtat ttagcgaata
    16681 aatcagagtt tactctggga catgttgaaa aattaatctc ggattggatt agtagtagaa
    16741 gcgaatttac aaaaataaaa cagccgatta aatttgacat gaaaaaactt ttgttaaata
    16801 agagtgagat aggtaataga gatcaatata ttagagctaa agggcaagaa ataattgatt
    16861 cattaggtga agtgaggtca tacaattatt tgtatgtaac acatagagct gatggaatgg
    16921 tcattactgt ggggaaatct tcttctaatg atattttttt agatggagat cttttttatc
    16981 aactcaatac aaatcacttg tctggcactg aaaatataat tttaaggacg gaatatggca
    17041 atgaaatatt tgcaaaatat gatgagattt taaaaaatta tttggactgg gcttggataa
    17101 ttccggttga gtcaggagat gctaagaaac tggagagatt attgggcgat gaactaatta
    17161 ataaaaaagt accaatttta aattattatt cccatagaca ataaaaggct atttttcatg
    17221 ataatactag ttataactgt aaaaatggaa gaaaatctgg gaaagaagtt tttaaataag
    17281 tgtattgttc gattttaata aataataagc aataccatcc gtctgtgttg cgcaacatcg
    17341 tactacaatg aatatttttt cacaaaaaga aaatcatcca tcgaatgaat ggaaggtttt
    17401 agtatacacg aggttaatgt cccctctttt ataatcagag gagtgaggtt ttttctatga
    17461 atgtttctat tttcttattg ctagtctagt ttctcttacg atgaaattgg gattctattc
    17521 cagtttttat tgatttgctg ataaaataac ttgaatggtg gatataaaca tgataaataa
    17581 gagaagaata acaaaacaag gttgtgaaat gattctcaaa taagtataat agaaagaaaa
    17641 aggaggaaga atcaatgaaa atagcaattg caggcgctgg cgcaatggga agtcgctttg
    17701 ggttaatgct tcaccaaagt gggaacgaag tattattaat cgatggctgg gcagaacatg
    17761 tccaacaaat caaagaacat ggattacaag caaattttaa tggtaaagag gtagaagcaa
    17821 aactaccaat cgttcttcaa tccgaagtag aaaaagaaga tcaagttgat ctgattattc
    17881 tatttaccaa agcgatgcag ctggaaaaaa tgctgcagga tatccaatca ttaatcaaaa
    17941 aagatacaga ggtcttatgt ctattaaatg gtatcgggca tgaagatatt attgagaaat
    18001 ttgtaccaat ggaaaatatc tatattggaa ataccatgtg gacggcaggt cttgaaggtc
    18061 ctggtcaggt caaattattt ggaagtggtt cagtagaatt acaaaattta ggtgatggaa
    18121 aagaagcagc tgcaaaaaaa ttagcagaca aattgtctga atcaggatta aatgctcatt
    18181 tttctgacaa tattcactat tctatttatc gcaaagcatg tgtgaacgga acaatgaacg
    18241 gactatgcac aatcttagac gttaatatgg ctgagctagg aaaaacatcg actgctcata
    18301 aaatggtggc gacgattgtc aatgagtttg ccaaagtagc agcagtagag aagattgaac
    18361 tagatgtccc agaagtcatt gcacattgtg aatcttgttt tgacccggaa acaattgggt
    18421 tacattatcc ttcaatgtat caagacttga ttaagaacca tcgattaaca gaaatcgatt
    18481 atatcaatgg cgcaatttct agaaaaggga agaaatatgg tgttgcgacg ccttattgtg
    18541 atttcttgac tgagcttgtc catgcaaaag aagatagttt gaacgtaaaa taaaggagag
    18601 attgaatgga aacttcacaa aaaatatcac cgaaaatttt tctgaataaa gtcctcgctg
    18661 gtacagcaac aggaatcatt attggattga ttcctaatgc agtattaggt gctattttaa
    18721 aatattttag tgcgtatccc tttgcggtaa cgatcgcaca gttagcagtt atttttcaat
    18781 tagcaacacc tttgatcatt ggtggtttga ttgccttaca atttggattt gatccgatga
    18841 gaatgatggt tgtagccgga gcttcttttg ttggttctgg tgtagtcaaa ttcacacctg
    18901 atttgggtga aacgggtgtt tacgttggtg ctggtacagg cgatattatt aatacgatgc
    18961 tgacagcatc gattgctgtc gggctgattt tactgattgg aaatagtttt gggtcagtgt
    19021 cgattgtgtt aacaccgatt gttgtaggtg taggtgcagg tttacttggt ttttatttat
    19081 tcccttttgt aacagcaatt acttctgcaa ttggatcatt gattaataac ttcactacct
    19141 tacaaccgct gttaatgtct atcttgattg gttgttcctt tgcctttttg attatctctc
    19201 ctatttcaac agtagcaatc ggaatggcaa tccaactaga tggtgtttct gctggtgcgg
    19261 ctgcgatggg cgtagctgca accacttttg ttttagtagt gaactcttgg aaggttaata
    19321 agtcaggtgt gacaattgcg attgctttag gcgctatgaa gatgatgatg cctaatctat
    19381 ttagaaaacc tgtgattctt attccttgtt tagttagtgc agtgattaca gctattcctg
    19441 tcgctctatt ttctatttca ggtacgcctg cttctgctgg tttcggtgtg gtcggacttg
    19501 ttggtccgtt ggcttcttta gatgcagggc taaatggctt tcttgttgtt ctttgttggt
    19561 tagtcatccc tgtttttgcg gcactaatta ctcaattttt atgcgagaaa gtatttaaac
    19621 tgtatgatcg agaagaagtc ttcaaatttt taggctagta gattttacta agaaattttc
    19681 aatcaatgga tgcgtaagtg agatgtcaac aacatctgac ttacgttttt ttgccaaaat
    19741 atggttttta ttttttatta ttaggtgtga ttagtgattt atcgacaccg tatatccttg
    19801 gcctttttta tcccaaactg aatcaaatga ctaccgtaat tagtgtgttt ggtgacgtag
    19861 atagtccagt cagacgtgct ttcttggtct ggtcagttgt atctggactt ttttttgttc
    19921 tttcgttgcc tgcgttgtat cacctatttg ttggaacatc aaaaacactt gcaatacttg
    19981 ctgttgcaac agttggttta tatgggatag gtgattgtat ttttactggg ttattcagta
    20041 tcaatacgaa tgaaagctct tggaatctat cgacttggat ccataataca ggttctgggc
    20101 taggctatgc aggctttcta cttttcccat tgttacttgt tctgctttat cgtcaaa
//
LOCUS       DAXQKX010000050        18895 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.051, whole genome shotgun sequence.
ACCESSION   DAXQKX010000050 DAXQKX010000000
VERSION     DAXQKX010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18895
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.051"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(21..251)
                     /locus_tag="ACF3MF_002001"
     CDS             complement(21..251)
                     /locus_tag="ACF3MF_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927966.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
     gene            complement(687..1253)
                     /locus_tag="ACF3MF_002002"
     CDS             complement(687..1253)
                     /locus_tag="ACF3MF_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFE3927967.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1253..2209)
                     /locus_tag="ACF3MF_002003"
     CDS             complement(1253..2209)
                     /locus_tag="ACF3MF_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HFE3927968.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2209..2865)
                     /locus_tag="ACF3MF_002004"
     CDS             complement(2209..2865)
                     /locus_tag="ACF3MF_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFE3927969.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3235..5253
                     /locus_tag="ACF3MF_002005"
     CDS             3235..5253
                     /locus_tag="ACF3MF_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFE3927970.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    5323..5529
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5680..8094
                     /gene="leuS"
                     /locus_tag="ACF3MF_002006"
     CDS             5680..8094
                     /gene="leuS"
                     /locus_tag="ACF3MF_002006"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HFE3927971.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8442..9995
                     /locus_tag="ACF3MF_002007"
     CDS             8442..9995
                     /locus_tag="ACF3MF_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WD40/YVTN/BNR-like repeat-containing protein"
                     /protein_id="HFE3927972.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10376..12160)
                     /locus_tag="ACF3MF_002008"
     CDS             complement(10376..12160)
                     /locus_tag="ACF3MF_002008"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3927973.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(12175..13896)
                     /locus_tag="ACF3MF_002009"
     CDS             complement(12175..13896)
                     /locus_tag="ACF3MF_002009"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3927974.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKQT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            13996..14757
                     /locus_tag="ACF3MF_002010"
     CDS             13996..14757
                     /locus_tag="ACF3MF_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFE3927975.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            15724..15992
                     /locus_tag="ACF3MF_002011"
                     /pseudo
     CDS             15724..15992
                     /locus_tag="ACF3MF_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            16664..>18895
                     /locus_tag="ACF3MF_002012"
     CDS             16664..>18895
                     /locus_tag="ACF3MF_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFE3927976.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTG"
BASE COUNT         6205 a         3352 c         3786 g         5552 t
ORIGIN      
        1 ctcattaaaa agcataacca ttactccgat ctgtttttaa aattagtttc tacctctaat
       61 atatatcgag tttttatttt gccttcagag aatactgttt ctttttttgc agttacaggt
      121 tgtttatttt cggaaaaagc taatatagct aagattgaaa catccatctg gaatttatct
      181 tttttactgc tttgatcata aaagtctgca tattcatcac tgatattttt tctaataaat
      241 tcttccatca taaaaatcac ctcaaaacga ttatacgaac ttacgttctt gttgtaaagc
      301 gatatttgag gggcaaaaaa ggggcataat ttgactgata ttaagttagc tattgatata
      361 tgaatgacat acaaaaatat aaaatctttt aaaaatgctt atatatcaat gtttttgcca
      421 ttcttttata tatctgttat atgtcaaaaa aatgtgttca atttcaattt gtatttgaat
      481 aaagaggttg tgaaaaagct gtcctgcatc aagtaataag aacagccaat caaaaacagc
      541 ttctcatgtt tttgatttgg ttggacttat taccgcagat ataagctttt gagcaccgtg
      601 aataaagagg ttatgaaatc aacgctctaa cctgagtatt agagaaaaaa acgcaaaaca
      661 tatcatttat gttttgcgtt ttttatttat ctttttttct caatacaata taaaataggc
      721 ggctggttct tttggttgat aaaccgataa ttcagcacat tatatgtttc ctgtggcagt
      781 ttggaacaaa aagaatcaac catatccagt tctttttctc caccttcatg accatagtag
      841 acgacaagga tcaatcgtcc gcgaggcaca agtcgtttca atatttcttc catagctgtg
      901 cgtgtagtct ctggcatagt gatgattgct ttatcacttt ttgggagata ccctagattg
      961 aaaatccctg ctttgagatt ttgttgttca gctatcactt ctcctaacgt ttcgtggcct
     1021 tgtagaaaca atgagacacg ttcttctaac tgacgctgtt ctagcctttc acgagtagca
     1081 tcgattgctt gttgctggat atcaaaacta tagacatgac cagtttttcc gatgtgttct
     1141 gctagaaaaa ccgtatcgtg gccattgccc atcgttgcat ctacgacgtg atcccctggt
     1201 tgcaagattt cttgcagtaa tgtatggctg aaatgcaaag cagtttgcaa catcagacgc
     1261 tcaccttttt ccgtacatca tattttcctt ggaagctatc tctgcgaaga agttcttcat
     1321 caattgcatt caagacttcc cattttttca agctccacat tggtccaatc aaggaatccc
     1381 acggcgcatc ccctgtcaaa cgatggatga tgatctcttt tggtatcatt tccagctggt
     1441 cgcaaatgac attgacatag tcaggacggc tcattaattg aaggcgacct tcatgatagt
     1501 cccgcaacat tctcgttttg cgcatcagat gcatcaaatg gagcttgatt ccttggatat
     1561 ctgaatctaa aatggtgcgt ctgacatttt ctttcatcat ttctaaactt tcgcctggta
     1621 atccgttgat caaatgcgta caaacacgga tattatgttt gcgtaattta gccacgccat
     1681 ctaaataagt ttgataatca tgtgctcggt tgatcagttt tgaagtttct tcaaaagttg
     1741 tttgcaatcc aagttctacc cataaataca tccgctcgtt cagttcagca aggtaatcaa
     1801 ctacttcatc tggcagacaa tccggtcgtg taccgactga taatcctacg acacctggta
     1861 aattgactac ttgctcaaat cgttctttga ttatttcaac tggcgcatgg gtgtttgtaa
     1921 aattttggaa ataaacgatg tattgttgga catgaggcca tttttgatgc atcatgtcga
     1981 tttctttctg gaattggatt ggaagagggt cttcaggtgc aacgatcatg tctcccgaac
     2041 cagatacact gcaaaaagta caaccgccat gggcaacagt cccatctcga ttcggacagt
     2101 caaatcctcc atcgatcggc accttgaaaa ttttcccgcc aaactcattt cgtaaagcgt
     2161 aattccaaga atgatatctt ttatttcctt ctgaataagg aaaagtcatt aaaagtcctt
     2221 ctttctgtaa gagttatcta tttgttttct tttttctcta tacactggat aagtcaggca
     2281 cagccaagaa agactgagta agtagccgcc gatgatatca gtaggaaaat gaacgcccag
     2341 ataaatgcgg cttatcccga cacttactat aataaacatc atcagcaatt gaagcaatgt
     2401 gcgtaaggtt cttttttgaa caaaagctgg aagcagaaat agtaaagaac cgtaaagaat
     2461 catactgcct gctgcatgtc cactagggaa actgtaactt gtttcaacta ctaagtgcgc
     2521 caatgaagga cgctctcgca tgaaaaatag tttgatcacc gggttgatga ttccagcaat
     2581 tacaataaat ccagaaacga accaaaatgt ttctgccctt tttttcttat accacatcca
     2641 taaagccgca caagcaaata aaatgatgac ggtaagagga ttaccgaatt tagtcataaa
     2701 gagttggtag ctgttcagat caggataaga agctctgaca atgcctgtaa accactgatc
     2761 gaaaccagaa agccacgaca gatggaactt tacgatccag cccaaaatga aaaacaggac
     2821 aagaaagaag ctaccagcca cctgaaatga tgttttatat ttcatacaat tcctcctttg
     2881 aagcaatgac ttattatagc atttttggtc cagcgaaaaa aacggtaaag agataaaacc
     2941 aatgtatgat tcctctttga ataaccaata ttcttataaa aaaaataact gtaatcggaa
     3001 agacattttt tggtaatgca aatgaaatgt tagggaaata aaatcagtgt ttttcgaaat
     3061 ccttttaaac aagaacgtag acgtaggaag aacttgaaaa tgaacagaag ttgttcatta
     3121 cggtaaatta caatatgatt acaaaaaaca acaaagctct taaataactt ttaataaata
     3181 ttaagagaag ttataattat taataataga taaattgaag ttggaggata gaagatggaa
     3241 aacattgcaa gaaaagaacg gagacgttta gaacagacca aacgttttcg aaaagcaaaa
     3301 cgaggggcag caatcgtggg aactgcgatg gtaggctgtt ctgtcgctgc cccattagta
     3361 cagccggttc ctgttcaagc ggatgaaaca cctgttcagt tcggcgcaag aatcaataca
     3421 gcggcattta tcacagaaat tgctacttat gctcaaccaa tcgctcaagc caacgatcta
     3481 tatgcatcag tgatgatcgc acaagcagtt gtagaaagcg gttggggcag tagtgcgtta
     3541 tctcaagcac cttattataa tctttttggg ataaaaggca gctatcaagg acaaaccgtc
     3601 tacatggata cgcttgaatt tttaaataat caatgggtaa ataaaaagga gcctttccga
     3661 caatatcctt cttttgctga atctttcaat gacaatgcct atgtacttag aaatacttca
     3721 tttggcaacg gttattacta tgccggtact tggaagagca acacgaaatc ctatacagat
     3781 gcgacagctt gtttgacagg gcgttatgcg actgatcctg gttacgcagg caaattaaat
     3841 aatatcatcg caacttacgg attgacccaa tatgatacac cagctagcgg aaacgcaggc
     3901 ggtggagcga ctacaggtgg caataatact ggaagtgcag gtagtactgg cggttcaagc
     3961 aattctggta atacaaactc aggttcagca acttcgacca cttatactgt ccaatctggt
     4021 gattctgttt ggggaatctc aaataaattc ggtatcacaa tggatcaatt gatccaatgg
     4081 aacaacatcc aaaacaattt catttatcca ggacaaaaac tgacaatcaa aggtagccag
     4141 gaaaatggct cttcgacgaa taattccggt aacaatacca actcttcagg aaatgctggt
     4201 acatcaaacg gaggacaaac aactggtgcg aaatacactg ttcaatctgg tgattctgtt
     4261 tggaagatct caaatgatca cggaattacg atggctcaat tgattgaatg gaacaatatc
     4321 aagaacaatt tcgtttatcc aggacaacag ctaatcgtat caaatggcgg ttcttctaat
     4381 gctggagcaa atactggctc aaatactggg aatacaagtg gctctagttc gtccagctca
     4441 agttcttcta atacagcttc aggaacgaaa tatacagtta aagccggaga ctctgtttgg
     4501 agcgtctcaa ataaatacgg aattacgatg gctcagctaa tccaatggaa caatatccaa
     4561 aataacttta tctacccagg acaacaactg actgtttcaa acagtggatc aacaaacagc
     4621 acgtcaggta atacaggttc gtcaaccaat acaaataaca gcagttcagt taatactggc
     4681 agcagttcgt ctcaaggcac ttataccgtg aaagcaggtg aatctgtttg gagcgtggca
     4741 aataaaaacg gcatcacgat ggatcagtta atcgaatgga ataatatcaa aaacaacttc
     4801 atttatccag gacagcaatt gatcgttaaa ggtggaactt cggcaaatac aaatacaggt
     4861 tcaactactt ctgcagcgaa accaaataca ccgaatacgt ctgctacgac aagtacatca
     4921 tccactggta atacgatgta taccgtgaaa gcgggcgagt cagtttggag cgtagcgaac
     4981 aaacatcata tcacgatgga tcagttaatc gaatggaata atatcaaaaa taatttcatc
     5041 tatccaggac agcaagtgat tgtgaagaaa ggttcatctc aatcaacaaa ccaacaatca
     5101 gttactggtt cgaaaaccta tactgtgaaa tctggagaat ctgtttggag tgttgctgac
     5161 agtcatggaa ttacaatggc tcaactaatc gaatggaaca atattaagaa caactttatt
     5221 tatccaggtc aaacgttgat tgtagctaaa taaaatagct gttcgaagaa ataacgattg
     5281 aattccacaa aaatatttgt tactataagg ctacttaaat atgacaacac ttgaaaagga
     5341 agtagtaaaa agactgaagt ttcagagagc gcatggctgg tgagaatgtg cacggatgct
     5401 tttgaactcg cctttgagtt gcccttgctg aatacccgag taagcaagcg gcggtgacgg
     5461 ccgttacaac gttcgaggcc ttttcactaa ggtaaaatta ggtggtaccg cgtagattac
     5521 gtcctataaa aagagcaatc tttttatagg atttttttat ttcttttgtg aagtttgaga
     5581 aaacaaagca aaaggaaata aaaataaaca gattctgccg gttttttcgt tatatttata
     5641 atagaaacaa gtgttttcaa tagaacagga ggacagcaaa tgagttacaa tcataaagaa
     5701 attgagaaaa aatggcaaaa atactgggca aaaacgaata ctttcaacac ccatgatgat
     5761 cctgaaaagc caaaatttta cgcactggat atgtttccct atccatccgg tcaagggcta
     5821 catgtagggc atcctgaagg ttatacggca acggatatcc tttcacgtgt gaaaagaagt
     5881 caaggataca acgtgctgca tccaatgggg tgggatgcat tcggtctgcc tgctgaacaa
     5941 tatgcgctag atacaggaaa cgatccagct gagtttaccc aaaaaaatat cgaaacattc
     6001 cgacgccaaa tcaattcttt aggatttagt tatgactgga atcgcgaagt gaatacaact
     6061 gatccggagt attataaatg gacacaatgg atctttacga agctttatga aaaaggtcta
     6121 gcttatgaag cagaagtagc ggtaaactgg gtacctgaat taggaacagt tatttcaaat
     6181 gaagaagtga tcgatgggaa aagtgaacgt ggtggctatg atgtagtcag aaaaccaatg
     6241 cgccaatgga tgctgaaaat cactgcttat gctgatcgct tattggatga tctagaatta
     6301 gttgattggc cagaaagcat taaagaaatg caaagaaatt ggatcggtcg ttcagtagga
     6361 gcaaatattg aatttaaagt ggctggtacg gataaatcct ataccgtatt tacgacacga
     6421 ccagatactc tattcggtgc aacttactcg gttcttgcac ctgaactaga tcttgttaga
     6481 gaaattacga cccctgaaca aaaagctgct gtagaagctt atatcgaaga gacagctaaa
     6541 aaatcagatc taaagagaac ggatcttgca aaagaaaaaa caggagtatt tactggtgct
     6601 tatgcaatca atccagttaa tggcaaggaa atcccaatct ggatcgccga ttatgtatta
     6661 tcttcatacg gcacaggagc catcatggct gttccagcac atgatgaacg tgactttgaa
     6721 ttcgctcaaa ctttcggact agaaattctt ccagttatcg aaggtggaga tgttgaaaaa
     6781 gctgcttaca cagaagatgg tacgcacatc aactctgaat ttctagacgg catgaacaaa
     6841 caagaagcaa tcgataaaat gaatgaatgg ctagaagaaa atggcgtagg gaaaaaagaa
     6901 gtcagctatc gcttacgtga ctggctattc tcccgtcaac gttactgggg tgaaccaatc
     6961 ccaatcatcc attgggagga cggaacagtc acagctgtcc cagaagaaga gctaccatta
     7021 cggttgccta agacaaaaaa catcaagcca agcggtactg gagaatctcc attagcaaat
     7081 atcgaggagt gggtcaatgt cgttgatcct gtaacaggta aaaaaggccg tcgcgaaacg
     7141 aatacaatgc cacaatgggc aggaagctca tggtattacc tgcgttatat cgaccctcat
     7201 aacaaaaaag aactagcaga ttatgaaaag ttgaagcgtt ggctaccagt tgacatctac
     7261 attggtggag cagaacatgc ggtacttcat ttactatatg cacgattctg gcataaattc
     7321 ttatacgata tcggtgttgt tcctacaaaa gaaccattcc aaaaactata caatcaagga
     7381 atgatcttag gcgaaaacaa cgaaaaaatg tcaaaatctc gtggtaatgt agtcaatcct
     7441 gatgatgtgg tcgaaactta cggtgcagat acactgcgca tgtacgaaat gttcatgggg
     7501 ccattagatg cttcgattgc ttggagcgaa aatggcttag aaggaagccg taaattcttg
     7561 gatcgtgtat ggcgtttgat cgttgatgag aacaataaaa tgcgtgaccg tatcactaca
     7621 ttgaatgatg gcaagcttga taaagtgtat catcaaacag tgaaaaaagt gacagaagac
     7681 tatgaaaatc ttcatttcaa tacagcaatc tcccaattga tggtctttat caatgaagcc
     7741 tataaagtgg acgctctgcc ttatgaatat atcgaaggat ttgttcaact actcgcaccg
     7801 attgctcctc acatgggtga agaactatgg gcaatccttg gaaatgatgg tggtatttct
     7861 tacgcaccat ggccaacata cgatgaagca gcacttgttg aagacgaagt agaagttgtt
     7921 ttccaagtaa acggtaaagt tcgtgcgaaa agcaatgttc cccgagactt aggaaaagat
     7981 gagctagaaa aagcagcatt agccaatgaa atagtgcaag aatatattga aggcaaaaca
     8041 gtcagaaaag ttattgcggt accaaacaag ttagtcaata tcgttgctaa ttaattggct
     8101 ctttgtcaat aaggactgat gagttgtgca aaatcaaatc tgggccagaa tgaacttcat
     8161 tctgtctcag attttttgtt atttcaaatt gattaattga ttgatcaaaa aggttttgat
     8221 tttcatgttc tcaaacacgt tcaatgtctt tttcttctga atggtcttgt aagagatctc
     8281 tgtaatcatc aaatttttgt ctattaatct tagtattttt tgatgtataa actacctgaa
     8341 attgagagta cataccaaat tcataaattt tttattagtg ggactagtga ttgtatggat
     8401 tttgacgcat aatgaatgaa gtatgagaaa aggagagaca aatggatcaa gaactattta
     8461 ttatcgaagt attatcagct aaacaaaaaa ttatcgagaa agcgaaaaaa agagcgaaaa
     8521 gaataatgtt caagctttta agcttagtat ttttctctgg tttgcttttt ttcggagctg
     8581 tatcgttcct atatcgccat atgagtgcag tagtccgttc agctgaaggg atgcaaaaat
     8641 taaataattt gtatcacttt tcgtggggag ttggcggaat aacaattgtt gtgcttattg
     8701 tttttcttct acttatttgg ctccgttacc atcaattgtc gcgtcatttc gatcaatggc
     8761 ttagtcaaag agcacaacag tttttacata ataaaccaac ttctcaagat gatgactatc
     8821 tttattttga gaagacttcg acgagtcaag cttttcggat acaaaaaagt gattgccagt
     8881 tattgctgag atcacttgat gatttaccta tctacttagg cgaaagcaaa tcaaaattcg
     8941 gaatgaacac attccatatt tttttactag aaaacgaacc cagatgggaa aaaagccagt
     9001 cttcgcctgg tggatacctg acaactaaga tgagtacatt agtcactggt tttttcctca
     9061 ttcttttagc tggaacaatc tattatggga gatacactca gccaaaaatg tcttctcata
     9121 taaatgctgc ttctcacatg acaatgaact caactaacga tacgcatata caaaagacaa
     9181 atgaagggtt gttagctgat cctaagcaaa aggtaaattt gacaacacaa aagataaatg
     9241 atctcaaact tgatacagag acgcactctc tctatatgac aacagatagt ggtgctaatt
     9301 gggtatttgt gccgattgat tcgcaatggt tgcgttttgg cgaatacacc ctgacaacgg
     9361 ggctgattcc tgaaggttat tggatggaca acacatatga tatttccgcc gatttctcat
     9421 ggtttatcta ttcttctggg gatgatgtac gtctgctgac ttcaagagat aatggtaaaa
     9481 catggcaaac gtctattatc acccaatcag ttcagccgat acgttatcga aaagcggtat
     9541 tttatggcaa cgatggtcta tttatctgta catcagccag tgggatgtct gcagaaactt
     9601 tgtacattta cactactatg gatggcggaa tcacttggat aaaaagtgga agtacaatga
     9661 tcaatcagcc agtacaaaat gtcagcttcg ttacaacttc tttaggtttt gtttcgacac
     9721 gtgaaagttt gttttataca aacaacggag gacgctcatt caaagaatca gttctgtcga
     9781 ttccggaaaa ctatcagaca ggggggatag atctttttca atcaccaaat gaagttactc
     9841 aaataagcgc gaatacgtta gagacaaaat tttatttgtt gaaaaaagga ccaatcgatg
     9901 cagggaaaat gtttgcctgc ctcttccgtt caactgataa cggggaaaca tggcaattcg
     9961 ttcagcaact atcgcaagta gaacaaggag attaaagaag agagattgtg agcctgacgt
    10021 tcagcaccga gtcacaagaa acaaattcaa aaaacagctt ctcatatttg ttgaatagtg
    10081 taactcgtga ttcggagttg acaagagcaa caagaagcga ttttgaagta tagcttctcg
    10141 tattttacaa gatcgtgtct tattgccgat aggttgtctc ttgaacaccg tttattcgta
    10201 aaaagggatt gtgacaagtc ttttgtcact acttaccgaa cgaaactgaa ggagctatcc
    10261 aaaaagtatc attagtatta ttctttgtgt ttctagtggc accactagta catttaaaaa
    10321 agctatcgat catggactaa tcatacatga tcgatagctt tttagataat gtttgttacg
    10381 ctatctgaaa ttgactatta taaagactgg cataaagcgt tggtgattgg agtagttcag
    10441 aatgtgttcc tttttcgacg atatcgccat tcttcattac aaggatcatg tctgcatttt
    10501 caatcgttga caaacggtgt gcaatcacaa aacttgtcct atcttttgtc acagcttcca
    10561 ttgcttgctg aatcaatgct tctgttcgtg tatctacgct agaagttgct tcatctaaaa
    10621 taacgacagg aggattcgct agaatgactc gagcaattgt caataattgt tgctgtcctt
    10681 gagataacgt gccgttttcg ctagaaatga tcgtatcata tccgtctggc agtgttcgaa
    10741 taaagtgatc acattgtgcg atttcagccg cttcgataat ttgttctctt gtggcatcca
    10801 ttttcccgta ggcgatatta tcagctaccg ttccttcaaa cagccaggta ttttgtaaaa
    10861 ccatcccaaa agaacgacgt agttctccac gtgaaagctt ggtaatatca agaccgtcga
    10921 attcgatctt tcctttattc agttcataaa aacgcatcag cagattgact aaagtcgttt
    10981 ttcctgcacc agttggacca acgatcgcta ccgtttgttt tggctttact gaaaaatcga
    11041 cttgattcat caatatttta tctgatgtgt aaccaaactg tacatttttg aaagctattt
    11101 ttcctttcgg ttgttctaaa agtcttgcat ctggaaggtc tggaatttca tctgtttcat
    11161 ctaatatctc aaatatccta tcgattgctg ccattgcgga ttggatcgag ttgatcacat
    11221 aagaagcggt agaaattggt tcagaaatct gattgatgta ctgaagataa gcttgtaaga
    11281 agccgatcgt cacaccacct gatagaacaa gcatagcacc gaataccgca cttatgatga
    11341 aggcgagttg attaatgaaa cgaatggccg gatagatagc acagttcata aattgagcac
    11401 gtttaaaagc gttgtattgc tttttattta cttcgtgtat agcagcttct gcatgagctt
    11461 gctgattgaa tgttttgacc actagattac cagctaagat ttcttccatt cgattattta
    11521 aaacacccag ttcatactga ttctgttcag aaatctgttt gtttttgttc gcaatcttag
    11581 ttgtaacaat tgaactgcca acgatcagca ataagacgag caaagtaagc ttgctttcga
    11641 tataaaacag catcagacca gcagcagcta ttgttacgac agaagtaaaa aattgattga
    11701 tacctgtcaa taacacttga gaaagttgat tgagaccggt agttgtccga ctaatgatgt
    11761 cacctacttg atgattgtca aaaaacgaca tcggtaatgt tttgaatttt tttgtgattt
    11821 cttttcgcac cctcaatgtg atcttttcgc ttaacgctgc cattgtccgt tcctgaataa
    11881 atgaagtgat gctgcttaag actgaacagc cgatcagcaa taagacaggg aacaacaatg
    11941 cttgtttgat atcactgaaa gaaagctgtc caatacctgt ttttcttatt tctgataaga
    12001 gatcatcgat cccgattccc atgatcaagg gcatggctac gactaatagg ttcccgaata
    12061 aactgcatag aaacaatccg taaaaatatt tatgttcagg tttgatcatt ttccaaaaac
    12121 gtatcaaagc acgcgtgttc aacgtttttt tcttttccat cgtatccctt ctttctatat
    12181 tccttgtgat tttgcaaact cctgataagt ttggcaatta gacagtagtt cttcatgagt
    12241 accttgtcca acgatttttc cttcatctaa aacaatgatg ttatctgctt gttggattgt
    12301 actgaggcgt tgagcaacaa tcacgagagt tttctccgac atgtgtttat gaagggctgc
    12361 tcttaatgct gcatctgttt tatagtctaa agcggagaaa ctatcatcga atacatagat
    12421 ctctgctggt ttgatcaacg ctcgagcaat acatatccgc tgtttctggc cccctgaata
    12481 attagaaccg ccttgagcaa caaagctgtc caatccgtca ggaagggtgt ccactagttc
    12541 ttctaattga gcgatcttga tcgctttaga caactcttct gttgaggcat attcatttcc
    12601 catctgcaag ttgcttaaaa ttgtcccgct gaataagaaa gccttctgag ggacataact
    12661 gatgtgggag cggatctgtt cttgagtcat ttgagtaaga ggaataccac caagggttac
    12721 ttttcctatc gtagggtcac taagtctcaa gagaagtttc gccaaactac tttttccaga
    12781 tccggtcccg ccaacgatcg ctgttgtttt tcctttaggt attgtgaaat caatatcttc
    12841 tagaactgga tcagagattt cagtatattt aaatgtgaca tgttcaaaag cagctgcatt
    12901 tgtctgatca aaggttggtt cagctactgt tttgatcgtc tcttcctcaa tttcgatctc
    12961 tgcttgcagt atttcttcta tccgtcgtaa tgaggcaaac gatttaggga taatgaccaa
    13021 taccatagct gcgatcatca agtaagcaag tgtcagcata gagtattcga ctacagcagt
    13081 cacgacaccg atttgtaatg ctccttctgc tacaagattt ccgccaaacc acaaaataga
    13141 agcataaacg attcccatga gcaaaaaagc aattggagtg acccaagcaa atattcggtt
    13201 cactttgatc atttgattag catagtcagc aaagctctta ttcgtttgct tttcttcata
    13261 tgattgatta tcaaaggcac ggatcatatt aatcccagta aagaattctc tcaatgtgat
    13321 ggtgatccga tccatttttg gctggatact caaagataaa ggtgcccctc gtttcatcag
    13381 tcgataaaca atccatacat aaaaaacaac agagatcaat gtaacccatg ttagtaatag
    13441 agaataacga aacatcatga gaatggtgaa aacgcaaata accggtgctg gtaagatcat
    13501 ttggcaaaat aaaacaatca tttgctggac attatcgaca tcattcgtca ttcttgtcaa
    13561 aagagatcca gaactaaaac gactgatatc cttcattgac agctgttgga atttacggaa
    13621 atatttctcc cgcgtttgga atccaaacct agcggaagcc aatgctgaaa agtaactaga
    13681 ggcaactgca gcgattgttc ctagaaacgc tacaagcagc atttcaactc caattttttt
    13741 tataactgag gcttcgccac ttgctatacc tgtgtcgatc agctttgcta ctaattttgg
    13801 tacacctaat gtaccggcga tttctaaaca gatcatcaca aaggtaagga gagcgagtcc
    13861 tttgtttttc tgtaagaatg tttttaagat agacatatta ttcctccttt tttcctgata
    13921 cttttcgatt ctataccttc aagtaacttg aaggtcaata gaaaaaagaa taaactgaaa
    13981 aagaggtgag aaaaaatgaa aaaaatgtat acgattggcc aagtatcgga actatttgat
    14041 ttgccaaaat caacgatccg ctattgggat gaacaaggat taatccgttc aagtagacaa
    14101 gaagagaatg attatcgatt gtttgatatc gatgatattt ttatgcttta tgatatcgtt
    14161 ttttatagaa aattagatat accgatcaaa cagatgaaga atttatatgg aaaaacattg
    14221 acggagttat atgagacact tgatgaaaca gaaagaagaa tccataaaga actggtggtg
    14281 atgaaacaaa aacaaaaaga gataagggag caaaaaaaac agttgaaatt gatgatcgat
    14341 acaaacgagg aagaatttcc tgtagaagag atcccttttg actgtatgat ctcaacggag
    14401 tttgaagata ttgtggaaat caaaaaattt ctacctaact attcaagctt tgggatgatg
    14461 agtatgccag cttccagttc acagacgatg tatggatttt ttatcgaccc tagtgaagta
    14521 catttattta ctcaagacgt gatttgggag aaaaaagata cggctgttta tcgtcgattc
    14581 ttattgaaat ccgagatgaa ccatgcggaa cgtaataata ttttagaaat cagagaaaga
    14641 atgtatgaaa aaggatggaa aacaggagaa gtgatcggcc agtatctatt gacgaatacg
    14701 gatgaaaaca atatcagaac tgaatattat catgcatgga tagaaatgaa aaaataggaa
    14761 atatgtgttt aagataactc gaaaatgatg gttgttttag ttataaagaa aaattttctg
    14821 gttcgattac gggtttaatg tgggggatta ttagtcgtgg atagatagaa ttttagtttt
    14881 ttagaggaaa tatgtcttta aaaatggaat ggttgcaatt cttagcgata tatacgatgt
    14941 aattgtcctc ttaaaaaagt atggaaaaat aattgtattg ggtgttatgt ataattcatg
    15001 gtgaactgag actaatgaga agaaaaattc atattgttat gagtgagatt gtatcagatg
    15061 agaatgataa attaaatagg tgcataaaag cattacactt aaaatacatt gttgcttaca
    15121 ttattacaat atgttaataa ggcaaaaata aatagatgga ttgaataaac atatttttta
    15181 atcaaatagt ccctactgtg actttcctca gctatcggtg atactaccga tagcattttt
    15241 ttgcttataa aataattata agtatttaga gatttttctt ctaacattct tcaaacaaga
    15301 aaaatcacaa aggttattgt tatttttata tattcttttt aagaatgatt gtttttttat
    15361 agaaatttta aaaaataaaa cacgttattg atggatagtt agtttgttat ttggtaatat
    15421 tatagaagtt gactggtagt gatttatttt tcgtcgtttt ataaaaatgt tattttttgg
    15481 aaaaattcac aaatatgtaa cgaatgtttt tctggaattt gctgtgttaa aaagcagtat
    15541 gactaatata aatactattg tcatttatgc aattttttat ggatagtaat tttagagggg
    15601 aatcaatgaa ggaagaatag aagggaaaaa tagttgcaaa tacgccagtt agcaaaaata
    15661 gcaatacatc ttcaagcttt aaaattcgag agaatcatct tggtagtgga atcaactaca
    15721 acaaaaggat taaaccaatt aatagataga attaccaatg gaaaaataga aaaggtagtt
    15781 attctataca aaagttgttt aattcgcttc ggttatgaac ttagtgaaac cctttgcaat
    15841 atatggtaca gaatatagaa attattgaca ttacagaaaa tgatgaagat ttaatacaga
    15901 ttgtcactat ttgtagatac cttttacaag gaaaccgagc caataaagct aagaagatga
    15961 ttaaggagtt gatggaagac gatacaagtt aagaaagtga aactacgccc aaataaagag
    16021 caaaaagagt aattggacgt ggaaaatgca agaaatgaac catcgattcg gtggacagtt
    16081 tattagtaat gacggtttga gaacatccat gacgagaatg aaggaacatc ctaaatgcgt
    16141 ttagttgaac caagtgccaa ataatatggc caaataagcg atcagttatc gatgaatccc
    16201 aagtattcta aactatatat tcattttgat gctaagcatt gatatatttt tttgggattg
    16261 atgaaggtta accaatacag ggactcactg atgaaattct agagtctgac cttggtatca
    16321 acgatttagt gattgtttct aatggaaaag tataaaagta tataagtaca ttaacaaaat
    16381 aactattagg gttacgctcc agcttgtgca aggcactggc aggaggaatc gtgaaatcat
    16441 aattatggtt aagccacacg gacaactaaa agtcatacaa agctatcgaa tcaatcaaca
    16501 gaagacaatc ggcaatcatt agctttgttt acagcttaca ttgcaacgct tgagttgaac
    16561 cgaaaatacg agggaggtaa cgcagccatt ttgagttggg gaatcttttt agaaaattat
    16621 cgggtacctt gttgtttagt caaaattata agggggagta atagtgagga acaaatttca
    16681 taaactgtta agtatgtttc tagttatgct tattgtgatc aatcaatttg ggaacataac
    16741 ggttctagct gagtctttag cagaacagcc agagcgttcg ctgacgatcg aagttgatca
    16801 agaggaggct gctttgggtg agcagttcca gttgcgagtc agaggaacac cagacctgct
    16861 aaatgcattg gtcattgata agagtgagga tttgattgaa ggggaagtga agcaactcaa
    16921 tgattacgaa cgtctgatta cttattcttc ccagcattca ggtaaatacg aattgaccgc
    16981 aagaagcggt gatattcaat caaatacggt ctcaatagaa atcagtgtac cagaagaaag
    17041 cacaagtgag tcttttaatg taccagaaga aagcacaagt gaatctttta atataccaga
    17101 agaaagctta agtgaatctt ttaatgaagc cagatcatct gagccatcta taacgcagga
    17161 atctcagatt gaaagacaag aggagctctt gaattatgac atcggcatct ctgctgagcg
    17221 ccccactttg ccgagcaggc atacacaaac gttaaaggga tacattcaag gaggcgctgg
    17281 cgatattctt gaagaatatg gggagatggt cgtacgagtt cctagagcat cgattggctt
    17341 aattgagttc attagagtgg aggtcgctga tgattcacct ttaaagccac tggcatttta
    17401 ccaagaaggc acagacgttg tttttccatt tacctttgat tatgaaggat taaatgaagc
    17461 cgctcagtcg tatacattca gtatcacgtt tgaagttgct ttctttcaat caggcggtac
    17521 tgagccaaat aatgactttc aagtgagtct tacttatgct gagcgagcag caaacacgga
    17581 attttcaatt acgcctattc cttcatcaag acccattttt tcgaaattat actatggctc
    17641 tagagaaatc gacagccaag gaaatcttgg gaatctgctg attgacgggc aagacgtgac
    17701 caacagtaat aaatttattt tgcaggtaaa ttatgaagga tcacgaaaag acggtgtagt
    17761 ggttaccgat gtactaccgc aaggaacaac tttggcaccg aatccgacta catggagttc
    17821 cactggaaat agagaaccta tttcaggtgg ggttcggatc gcagaagtaa cgaatccagg
    17881 tgaagcaaac gttagaactc attatgtttc cgaggaattt gtggacaaag tatcttttaa
    17941 taaggaaacg aatacacttg ttgtggactt tggtaatcta gcagagggtc aatcgtattt
    18001 tattgaatat gctcttgaag tgaccgatgt cgacttgttc aatgaaggaa gacaagagga
    18061 tgggttttct cggaatcgag cgagtatgac ctacaataat caggtaatga gccgagacta
    18121 ccgcttgaga atccctgaaa gtaatcttcc ggcaatctct ttaagaaaaa gtgtggacaa
    18181 aaatgttatc aatctcaatg aaaatgaact aacgtatact ctgcatgtct cgatgttttc
    18241 tggaacaaga aatacgcttg ttattgaaga tgttttggaa gaaggcatgg aatttgtgtc
    18301 atttctatca gatattccct ctttcattga tgccgaagtc aataatggaa tagttcgttt
    18361 cagtgcgaat aatacgattg gtggtccgac aagttttacc ctctctttta aggtcaatgt
    18421 agaggcgtat gcggtcggcg atcaaatttt aaactttgca acgcttgtga atagtgacaa
    18481 tcgattgaat acgagtactg taagaacaag gaaaatcgat gggcgtatta aagtaattaa
    18541 aactgatgag aatggccaaa ggctggcagg agcaaaattt gaaattttat caagcgattc
    18601 acaagtgata caagaaggta taacggcaga aaacggagaa tttttaagtg aaccgcttcc
    18661 tgtaggtagc tatcaagtcc gagaaacaga agcaccggaa gggtatcttt tagatgcgac
    18721 ggtacatgat gtttttataa atgaatactc catagaagaa gtgacgttaa ccattgaaaa
    18781 catccttgat acgggtggtg ttgaactaat taaacatgct gaaggcagtg gtgaagtcct
    18841 tcaaggagct gtttttgagt tacagaaccg agaaggagaa acgctacaaa ccggt
//
LOCUS       DAXQKX010000051        18725 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.052, whole genome shotgun sequence.
ACCESSION   DAXQKX010000051 DAXQKX010000000
VERSION     DAXQKX010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18725)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18725)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18725
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.052"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(167..2845)
                     /locus_tag="ACF3MF_002013"
     CDS             complement(167..2845)
                     /locus_tag="ACF3MF_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
                     /protein_id="HFE3927977.1"
                     /translation="MKIIEKKIANKKINWLVVNFLVLIAMIIFTSNIAHASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSAVNTIVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALI
                     LLMPTMISSGIQFAKTFYKDSTTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNNLTRKNFQQTDLTQVLTDKVIDKLEKENPIADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNSGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGE
                     GEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATKPFKSMRDI
                     ANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSVPTRLSDRKDGAKVEN
                     ADRIMSSSERMREAMKNNAESNNNPASAIQQKVQQDIEERKNAMHGQAKSAEELINQK
                     RHEAKYTPEAMNREEIMLRKRVEGRTGANIDGKEALTKERIQEAKNSNTGLEKLVKEN
                     PQNSTSSHGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNAQGTKTIDVRENLQSS
                     STSQPKTVDVRENVQNSTSSQGFKSVDVRENVQGSSASQPKTVDVRENVQSSTSSQGF
                     KTVDVRENIQKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKSR
                     RRFTYEDNELFRDTLNDPNPLFDNLLRNKRGGLSCN"
     gene            complement(2832..3050)
                     /locus_tag="ACF3MF_002014"
     CDS             complement(2832..3050)
                     /locus_tag="ACF3MF_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927978.1"
                     /translation="MIKNRLIDQVWCLDQNTDSLELIETICFNTIVLDLRAENDNCVT
                     HVIINQKMAQKLSESLRKWAKGGNDENN"
     gene            complement(3126..4178)
                     /locus_tag="ACF3MF_002015"
     CDS             complement(3126..4178)
                     /locus_tag="ACF3MF_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HFE3927979.1"
                     /translation="MNEKEVESLVEKQGYSNSDIYAELYYQYPIFLNVNEKYKKMKLS
                     SKLVYMLLKDRNRLSLKNNLYDENQKIFLIFEIKNLVEISGMSKNTILSALDELQKVK
                     LLVKRKNGFNKSKMQMFPNFYYLLKPVLCKDDVYKINKITHQENRQKNLIVQNLNYGT
                     NQYSVDNSKFELCDTSMKTRDKNNFADSSKNELELYKSYKDSKDIKESHNDDLLESLS
                     TKNNKLDEELIETFIEENLLKQIWGESIVNCLKLASNSDYRQFDNWYKKFKYAIRSAE
                     KEQKIQLKIIYEICNNKYFVDHVREQLSMTLRDLIRRAKTDHRIKQKDDYIFASLKNK
                     ALELIELQISEGIDKQ"
     gene            complement(4331..4657)
                     /locus_tag="ACF3MF_002016"
     CDS             complement(4331..4657)
                     /locus_tag="ACF3MF_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3927980.1"
                     /translation="MASWLIEEIENERRKIMDAGITVMLDKQQTNQLKNYVFEMTKEA
                     IDQARIDTGLERPFLKGKEMAKYLNVSYTTFLKFKRMGLPVILLEKMELFSKEECKKW
                     ILSHQI"
     gene            complement(4669..4869)
                     /locus_tag="ACF3MF_002017"
     CDS             complement(4669..4869)
                     /locus_tag="ACF3MF_002017"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3927981.1"
                     /translation="MITLNDQFIRSLRRHRADLILTKNDAAKLIGINRKTYVKIENGS
                     KESIRASTYQKLVNWLLNDLKI"
     gene            4992..5594
                     /locus_tag="ACF3MF_002018"
     CDS             4992..5594
                     /locus_tag="ACF3MF_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFE3927982.1"
                     /translation="MEFTIGGVTLNRIKFYIDSSKKTIKQISTETGINYTTLTNYYRG
                     ERNPRNTETWNILADYFHVPVSYLMGLDETNSIEQPNLDRIKTARLEKKDKIVKNIAS
                     LDSDYFTELSNLYFSMTSLLEVKLQEDDSDFLFLKSILEDSFEYTILFAKQKKFINKA
                     LNLNIDERKELESELFGNLTQVQVNNLKREITARLISKLQ"
     gene            5649..6815
                     /locus_tag="ACF3MF_002019"
     CDS             5649..6815
                     /locus_tag="ACF3MF_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFE3927983.1"
                     /translation="MSIQKYTTKSGARYSVRLYVRKDENGKQEYYVKKGFKTEKEAKL
                     HEARKKVEIEDTGYHKPSNDLFITVYEEWLPSYRNRVQETTYQRTKDLFRLHILPKFG
                     NKSISKITPVHCQNAVNEWALKFKNIKQLKSYSSQIFEYAIFAELLHRNPMANTNLPK
                     REKKENENYFSLEELKAFWDILNKEEPLKHILIFQLLITTGIRKGELAALHWSDIYFE
                     EQLMYVRKSYATIRNEEKNARRKTVRIQKNTKNISSERILPIDAQTIEMLKIWKKEQA
                     RELLQFGINTNTKNQLIFTYVNADGDINQPLHADYSNNILKRLEKKYKFKHVTIHGFR
                     HTHATLLLEGGASIKETQDRLGHKNAETTLNTYSHVTEKAQRNALEKFIAYTGL"
     gene            7232..10459
                     /gene="fss3"
                     /locus_tag="ACF3MF_002020"
     CDS             7232..10459
                     /gene="fss3"
                     /locus_tag="ACF3MF_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HFE3927984.1"
                     /translation="MYKKQKKKLCVLTILSLAVQSIVGAIAPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCVEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIADYQKKPSFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENTANIDYRVN
                     GNQLIISPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTVKIDVE
                     MEGSLKIKKVDKESGDIIPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTATIKAGETISVTSKNTREKGQIILDKTGIETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGHETQGKAEFKRAEYTL
                     FTVKDGKAVKWTENFKPELLKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDSEKNAVITRDVAAKEQVIRFGFDFFKFAGSTTGTAETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDYTKSDYIFTITEKGQKQPIKTVTVPYGNLTNENFSVSLNR
                     LMLYDLPEEEDSLTSLATWKEGDKELTTLDSTELVDKLSYNLHEIKEDWYIVAQAIDV
                     DATKAAQEKDKKAKPVAIAETTATLANKEKTGTWEILHKLTVEQVLDKTIVLFNYVYE
                     SKEAYEAGDEPVAKDASLNNQAQTVNCMVERHVSIQTKAHLEEGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALFPDGTSKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYDKDGNINGKHNEDLKEKSQTLTPKKVPTTPSTPEQSEMPTVP
                     SGSQESSPTVKAFPQTGEKTSNVLLFIGFSLIFATAGYYFWNRRN"
     gene            10571..10885
                     /locus_tag="ACF3MF_002021"
     CDS             10571..10885
                     /locus_tag="ACF3MF_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFE3927985.1"
                     /translation="MELKFVVPDMVETFGKLTYGGEGEVLSEGYGRNTTIVGRSYHLF
                     SNKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLIAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            10898..11272
                     /locus_tag="ACF3MF_002022"
     CDS             10898..11272
                     /locus_tag="ACF3MF_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFE3927986.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQLNQGKPTNQNEGKK"
     gene            11282..11626
                     /locus_tag="ACF3MF_002023"
     CDS             11282..11626
                     /locus_tag="ACF3MF_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HFE3927987.1"
                     /translation="MEINVEHILDCLDQFGKGELTEEQLTNALTYDEKMFLIMHQGLL
                     EVGNDAKEDFDVLDWLGEEESFFMVVEVNESLCRQAESVLEEIDVEMPDAIERFLKQL
                     VETKQLPVVVND"
     gene            11695..12711
                     /locus_tag="ACF3MF_002024"
     CDS             11695..12711
                     /locus_tag="ACF3MF_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HFE3927988.1"
                     /translation="MYKGHRIRAGDQHLIYHFVLGWLIFLFIGWMSVFYLQELRQFDI
                     SKVSFSTSEIGWSMKDVICLLGSLALSGSMMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQGEGFFKDLNSSWTKESISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLR
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIEEIVAENGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIQALLKSDAELFILDPKNADLADLGTIMPHVYSQK
                     EEISECVEDFYERMIARSRSMKEMPNYKTGENYAYLGLPPNFLIFDEYVAYMGANRFP
                     TSIE"
     gene            13305..15179
                     /gene="ltrA"
                     /locus_tag="ACF3MF_002025"
     CDS             13305..15179
                     /gene="ltrA"
                     /locus_tag="ACF3MF_002025"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFE3927989.1"
                     /translation="MNVETDEVQGSGKNVGKSVMEVPRLNTKIRYWEYYDLQETFDQL
                     FTQSRNGKKFYQLYELIISENNILLAYRTIKANKGSSTPGTDSFTIDNYKEMNQAEFI
                     HLILSHLENYKPKSIKRVMIPKPNGEKRPLGIPCMIDRMIQQMFKQILEPICEAKFYE
                     HSYGFRPLRSAKHALGRIMYLINISKMHYAVDIDIKGFFDNVNHRLLIKQLWNIGICD
                     KQVLAILSKSLKSPIQGEGIPSKGTIQGGIISPLLSNVVLNDLDHWVSKQWHTFETKY
                     PYTKGYNKFRALRDTNLKQGYIVRYADDFKIMTNDYPTALKWFHAVKLYLKDRLKLDI
                     SNEKSKIVNLRKCKSEFLGFAICVKQKGKKWVCNSRISNKKKDQIKEEIKQRIKDIQK
                     SPTAQNALLFNALVLGVHNYFRYATHINLDLNRMNYVLSFTTYNRLSNCSTRCYPNKA
                     SPTYKKFYSTTMKTYKVAGVYLYPLCDVSTKTIYGFNTEDTPFTPFGRQRLEHKSLQS
                     LVYQELRKLMESKIPNRTVEYLDNRISRYSMKSGKCEITKQFLPAKAVHCHHYLPKSL
                     GGDDKFDNLRIIHKDIHLLIHTTNKMIIDHYVNELKLLPEQIAKINLYRKMCNLQNIQ
                     "
     gene            15281..15661
                     /locus_tag="ACF3MF_002026"
                     /pseudo
     CDS             15281..15661
                     /locus_tag="ACF3MF_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            15706..16848
                     /gene="dcm"
                     /locus_tag="ACF3MF_002027"
     CDS             15706..16848
                     /gene="dcm"
                     /locus_tag="ACF3MF_002027"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HFE3927990.1"
                     /translation="MTFLDLFAGIGGFRLGMEQAGHQCIGFCEIDEFARRSYKAIHDT
                     RKEVEMHDITSVSDEFVRSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     ATLLQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQSRERI
                     FLIGHSRDACTEQVFPIIGSSSTSDQNIRNLVNINPSNRGMGGQVYGSDSVAPTLTGD
                     EGIKIALPVKDGISVAGMLSGNFEQGNRIYEVTGTAPTLSTKQGGTKIMIRKNETEYQ
                     EVKPGDSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKGVKAYDL"
     gene            16838..17127
                     /locus_tag="ACF3MF_002028"
                     /pseudo
     CDS             16838..17127
                     /locus_tag="ACF3MF_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            17383..18567
                     /gene="mobT"
                     /locus_tag="ACF3MF_002029"
     CDS             17383..18567
                     /gene="mobT"
                     /locus_tag="ACF3MF_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobT family relaxase"
                     /protein_id="HFE3927991.1"
                     /translation="MAQRNLDYRLLKERRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     IASTKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDVRKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYYAIQDLL
                     KGRSIESTTFSIINRYLRFADKVDGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     IV"
     gene            18564..18677
                     /locus_tag="ACF3MF_002030"
     CDS             18564..18677
                     /locus_tag="ACF3MF_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HFE3927992.1"
                     /translation="MKRGILMEIVKDMLLVLGGSMLGVTVMCLMNASAAAD"
BASE COUNT         6130 a         3270 c         3561 g         5764 t
ORIGIN      
        1 agagagcaac atttgaaatt gctctctatt tcatttttca tctttaattc ttcttgaatc
       61 atcagttcaa tataattagt gaccgtgatt ttttcatttg ttgcgttctt tactgattca
      121 cataattcgt caagttctaa gaaatcatgc gtactaatct ttagaattaa ttgcatgaca
      181 atccccccct tttatttctt aataaattat cgaaaagtgg attaggatca ttaagtgtat
      241 ctctgaataa ctcattgtct tcataagtga atcttcgtct tgattttgat cccttatcat
      301 tttcacggat ttcactatca ataatcactg tttcatgatt tgaatcaaat tttttcgctg
      361 actttctgtc ttcaacgata ttgatttttt gtgttttttc tttcatttct ccactatctt
      421 tttgaatgtt ctcccgaaca tctactgttt tgaatccttg actacttgta gaactttgta
      481 cattttctcg gacatctact gtttttggtt gacttgcact gctaccttgc acattctctc
      541 ggacatccac tgatttaaac ccttgactac ttgtagaatt ttgtacattt tctcgaacat
      601 ctactgtttt tggttgactt gtactgctac tttgcagatt ttctcgaaca tcaattgtct
      661 tagtaccttg agcatttgaa gaactttgta aattctctct tacatcaaca ttccgtccaa
      721 catgaccatt cagtgaacct tgaatatttt ctcggacatc tactgatcgg ccaccatgac
      781 tacttgtaga attttgtgga ttttctttga ctaatttttc taatcctgta tttgaatttt
      841 tagcttcttg aattctttct ttggtcaacg cttcttttcc gtcaatatta gcgcctgtcc
      901 gcccttctac acgtttcctt aacattattt cctcgcgatt cattgcttca ggcgtgtatt
      961 tcgcttcatg acgcttctga ttaattaatt cttcagcaga cttagcttga ccgtgcatag
     1021 catttttacg ttcttcaata tcttgttgga ctttttgctg aattgcgctt gcaggattat
     1081 tattcgattc agcattattt ttcattgctt cacgcatacg ttcagaacta gacataattc
     1141 tatcggcatt ttcaacttta gcaccatctt ttctatctga aagacgtgtt ggcacggaat
     1201 cagcatattt tccagtttca tcttctttat ttttagctaa cataggtttg ctatttttat
     1261 taatagcgga cactgtacca tcatctaaac cttctttaaa cttattcttg gtatcattag
     1321 ctatatcacg catactctta aatggttttg ttgctctttc actagccatt gtagctccat
     1381 ctgaagctaa accggataat ccacgttcat gggcatatcc caaagctctt ccagttttgc
     1441 cagctttttt tgatagagtt tcgccgaaat tcttttctgg ttttcgatct tctccttctc
     1501 cgcttccttt agcacgatta aatccatttg atccttttct aaacagcatt gcgcccattc
     1561 caaaagcaga agcaagttgc ccatagcctt ctttgagtcc aatatcaaca ccaaagtatc
     1621 tcatgactgt tccactgcct ttgattaaaa caaaaacggc acagatataa gcaattgttt
     1681 ttataaaaat atttgttgag ataccttgtc ctgagttcag aaaattgata aacatagcaa
     1741 acattgataa cccaaatcct tgaaacccaa cagttaagta acattgtaga atatctgata
     1801 gaacaacttt tgaacgctgt cctgtctcaa tatctgttgc aaaaacaaga acacctaaca
     1861 cacgtttaaa tgcaagttct agtattgctg taatgatcac aaacgcgctg aacacatagg
     1921 cgattgctaa cgctgtcaac ccaattgaaa tcccccatag atttgcttgg tatcggtaat
     1981 agcctgattt caagctatca gaaaatgttg ataagaagtt gtcagaaaac tttgtagcaa
     2041 caaattcatt attagaattt tcaactaatt cataacgaag attgtccgca attggatttt
     2101 ctttttccaa tttatcaatc actttatccg ttaacacttg tgtgagatcc gtctgttgaa
     2161 aattttttcg tgttaaatta tttcgatcct ccgttttatc aatgcttgag tactgatctg
     2221 ttttattaat atatgctaaa tctgttactc cttgttttat caatgaccaa gcgactccgt
     2281 catctgaatt tgtaatcgta gtagagtcct tataaaatgt tttagcaaat tgaataccac
     2341 tagaaatcat ggttggcatt aaaagtatta atgctataga catcactacg ttcattccaa
     2401 ccgattttaa atccactgtt ccttttccag taatcatttt gtaaccaaca aacatcaatg
     2461 aaaggatcat taatccaatg acaattgtat ttacggctga ttgataaaca ttatttagcc
     2521 ctgtactttc aatgaaattg aacaaatcca gcacatctgg aatcatattt tgaatcgaat
     2581 ctgtcacagt aaacatgcct tttaccacag cccatccgag ccaaatcccg aactgactaa
     2641 ggaaatctcc attgtacttt tttaggtaag gtctataaag agaattattc aaaaactctg
     2701 tttgactttt tgtgtcatca aaccaattga aaatactcgc atgagcaata ttacttgtaa
     2761 aaataatcat agctatcaga acaagaaaat taacaaccaa ccaatttatt tttttattgg
     2821 caatcttttt ttcaattatt ttcatcgtta cctcccttag cccattttct gaggctctca
     2881 gagagcttct gagccatttt ttgattaatt atgacatgag ttacacaatt atcattttca
     2941 gctcttaaat cgagaactat agtgttgaag caaatagtct cgattaattc gagactatct
     3001 gtattttgat ctagacacca aacttgatct attaaacgat ttttaatcaa aataacccct
     3061 cctatattca aagttctcaa atgaagtgga gatacccctc catttcattt gactcaattc
     3121 tattcttatt gcttatctat tccttcgctg atttgcaatt caattagttc taacgcttta
     3181 ttttttagag aagcaaagat ataatcgtct ttttgtttga tacgatgatc tgtttttgct
     3241 cttcgtatca agtcacgtaa agtcattgat agctgttctc taacatgatc tacaaaatac
     3301 ttgttattac aaatttcata gataattttc agttgaattt tttgttcttt ttcagcagat
     3361 ctaatcgcat atttgaattt tttgtaccag ttgtcgaatt gacgataatc actattgcta
     3421 gccagtttta agcaattcac aatactttct ccccatattt gtttaagaag attttcttca
     3481 ataaatgttt cgatcaattc ttcatctaat ttattatttt tagttgaaag tgattcaaga
     3541 agatcatcat tatgtgattc tttaatatct ttactatctt tataagactt atataattct
     3601 agttcatttt ttgaactatc agcaaaattg tttttgtctc ttgttttcat tgatgtgtcg
     3661 catagttcaa attttgaatt atcaacagaa tattgatttg ttccatagtt caaattttga
     3721 actatcaagt ttttttgtct attttcttga tgggttatct tattaatttt ataaacatca
     3781 tctttgcaca gaacaggctt taacaaataa taaaaatttg ggaacatttg cattttactt
     3841 ttattgaagc cattttttct tttcacaaga agtttaactt tttgaagttc atctagtgct
     3901 gataagattg tattttttga cattcccgaa atttctacga gatttttgat ttcaaatatc
     3961 aaaaaaattt tttgattctc atcatacaag ttatttttca atgaaagtct atttctatct
     4021 tttagtaaca tataaactaa cttagaactt agtttcattt tcttatattt ttcatttacg
     4081 tttaaaaaaa taggatattg atagtataat tctgcatata tatcagaatt agaatagcct
     4141 tgcttttcaa ctaagctttc aacttctttt tcattcattg tcacacctgc ttctgatttt
     4201 atttgctata atagattcaa ataaagtttt ctcagaactt tattattgag tgttcccccg
     4261 atctgcaaac tgacgggaac actcttttta attttttcta cttcatcaaa tttaaaaaac
     4321 gaggtgtttt ttaaatttga tgactcaata tccatttttt gcattcttct tttgaaaaca
     4381 actccatttt ttctaataaa ataactggca atcccattct tttaaatttc aaaaaagttg
     4441 tatatgatac attcaaatat ttagccatct cttttccttt tagaaatggt ctttctaatc
     4501 cggtatcaat tcttgcttga tcaatagcct cttttgtcat ttcaaaaaca taatttttca
     4561 attgattcgt ttgttgttta tctaacatta ctgtaattcc tgcatccatt atttttctcc
     4621 tctcattttc tatttcttca atcagccaac tcgccaagtt gtatttattt agattttcaa
     4681 atcattaagt aaccaattta ccaacttttg ataagtagat gctctaatac tttctttgct
     4741 cccattttcg attttgacat atgttttccg atttatacct atcaattttg ctgcatcgtt
     4801 tttagtaagt ataagatcgg ctctatgtct tcttaagctt ctaatgaatt gatcattaag
     4861 agttatcatt cagcgcctcc tttcaaatta ttcactttgt ggtttttatc ttaataagca
     4921 cattttaaac cacaaaacga gtaatatcaa ttaaaatatt actcaatttg tggttttcat
     4981 gctataatag tttggaattt actatagggg gcgttacttt gaatagaata aaattttata
     5041 ttgattccag taaaaagacc attaaacaaa ttagtacaga aactggtatt aactatacaa
     5101 ctcttacgaa ctattaccgt ggtgagcgaa atcctagaaa tactgaaaca tggaatatcc
     5161 ttgctgatta tttccatgtt cctgtaagtt atttgatggg attagacgaa acaaattcca
     5221 tagaacaacc taatcttgat agaataaaaa ctgctcgttt agaaaaaaag gacaaaatag
     5281 tcaagaatat tgccagtctt gactcagatt attttactga attatctaat ctatactttt
     5341 ccatgacttc tttacttgaa gtcaaacttc aagaagatga ctccgacttt ctttttttaa
     5401 aaagtattct agaggactcc tttgaataca cgattctatt tgccaaacaa aagaagttta
     5461 ttaataaagc tttaaactta aatatcgatg aaagaaaaga gttagaatct gagttatttg
     5521 gcaacttaac ccaagtacag gttaacaatc taaaaagaga gataacagct cgattaatat
     5581 caaaacttca ataaaactaa ttattcaatc agccaactcg ccaagttatc agattggaga
     5641 gattagttat gtcaatacaa aagtacacaa caaaaagcgg tgcacgatat agtgtccgct
     5701 tgtatgttcg taaagatgaa aatggaaagc aagaatacta tgtaaaaaaa gggtttaaaa
     5761 ctgaaaaaga agccaagtta cacgaagcaa gaaaaaaggt cgagattgaa gataccggct
     5821 atcataagcc ttctaatgac ttgtttataa cagtgtatga agaatggttg ccttcttata
     5881 ggaatcgtgt acaagaaacg acatatcaac gtacaaaaga ccttttccgc ttgcatatac
     5941 taccaaaatt cgggaataag tccatttcta agattactcc tgttcactgt cagaatgcag
     6001 tcaatgaatg ggctttaaaa ttcaagaata tcaaacagct taagtcttac agctctcaaa
     6061 tatttgagta tgccattttt gcagagctat tacaccgaaa tcctatggca aatacaaatc
     6121 taccaaagcg ggaaaagaaa gaaaatgaaa attacttttc attagaagaa ctaaaagctt
     6181 tttgggatat tctcaataaa gaagagcctt taaaacatat tttaatcttc cagcttttga
     6241 ttactactgg tatacgtaaa ggagagctag ctgctcttca ttggtctgac atttattttg
     6301 aagaacagct aatgtatgtt agaaagagct atgcaactat tcgaaatgaa gagaagaatg
     6361 caagaagaaa aactgtcagg attcaaaaaa atacaaaaaa tatatcttcc gaacgaatat
     6421 taccaattga tgcacaaact attgaaatgt taaaaatctg gaaaaaagaa caagctcgag
     6481 agcttttgca gtttggcata aatacaaata caaaaaatca acttatcttt acctatgtaa
     6541 atgcagacgg tgacattaat caacctttgc atgcggacta ttcaaataat atattgaaac
     6601 gtttagagaa gaaatataaa tttaagcacg ttactattca tggattccgg cacactcacg
     6661 ctactcttct actagaaggt ggagcaagta tcaaagaaac acaagatcga ttgggtcata
     6721 aaaatgctga aactaccctt aacacttatt ctcatgttac tgaaaaagct caacgaaatg
     6781 cgttagaaaa attcattgct tacactggtt tataatattg tcattacctt tctcattacc
     6841 agaacgaaaa aaagacacct tctcgcaatg agaaagtgtc tgaaatcgtt ggtataacaa
     6901 cgattaacgt tttgaaaact gtgaagcttt acgtgctttc ttaagacctg gttttttctt
     6961 cgtatcattg aataagtttg aaaagccttg atttataaag gtttttccgt aaatatattt
     7021 tgttatattt gattaaattt gaaatgtttg tgttctaaaa tgtgttctaa tttaaaggca
     7081 gtatatttcg tattttatat taaattttta ggctcattca ttctcaaatc cattctattt
     7141 agtcaataaa tattttaaaa agactttata aacaaagatg ttcaagcgag catcttattt
     7201 ttttgtgcct aatttgaaag gagaacattt catgtataaa aaacaaaaaa agaaattatg
     7261 tgtattaact attttgagtt tggctgttca atcaattgta ggagcaattg ctcctacgat
     7321 tgcttttgct gatgaaatta cccatccaca aacggtaacc gtagaactag atttagcaca
     7381 tcaatatgct gttgaaggaa cttttagtga tggtcgtcca atgtcagaag tcactgttcc
     7441 gcattatgca gtgtacaacg gcgttaaaca agatattttc tgtgttgaac caggagtccc
     7501 gatttacaat gagttcactc ctggatatga gaagaacccg ttaccagata tgtccgataa
     7561 agccaaatta gtttccgttt tatggaaaaa agtaggtaca gatgcagata ctcatattgt
     7621 ggcacagaag atgatctggc aagaagttaa tgggtatacc cttcactcaa taaaacgatc
     7681 agatggtagt gccgtaaata tcgcagccat tgaggcaaaa atcaatcaag ccattgccga
     7741 ttatcagaag aaaccaagct tccataatag tacggctaaa acagtattag ggcaatcgac
     7801 tactgtgacg gatacgaata atctgaattt gtcagagttc gatgaggttg tggaaaatac
     7861 cgcaaacatt gattatcgtg tgaatggcaa tcagttgata atcagcccaa atgccaattc
     7921 aaaagaaagt ggtgtgttga cgcttaagaa atctgctggt accggaacac ctgtcgccta
     7981 taaaaaggct ggccaacaga ctttaatggc cggggcgatc gataagccga acacttatac
     8041 ggtcaaaatt gatgtggaaa tggagggttc tttgaagatt aaaaaagttg ataaagaatc
     8101 gggtgatatt ataccaggaa cggttttcca tttagacttt ggaaaaactt tacccgcaaa
     8161 agacgtgacc accgataaag aaggcattgc gaccttagat gagattcctc atggtacaaa
     8221 ggtaaccatt actgaaaaat cggtgccggc gccttatacg attgatacca cacccatgac
     8281 tgccacaatt aaagcaggtg aaaccatttc agtgacttca aaaaatacgc gagaaaaagg
     8341 tcaaattatt ctggataaaa ccggaattga aacagggagt gatctttgga acgataatta
     8401 ctctttagcg ggcaatacgt ttgccattcg caaggatagc ccaactggtg aaatcgtcca
     8461 agaaatgacc acggatgaaa aaggtcatgc agaaacacca aaagagattg ccaatgcgtt
     8521 ggaattggga acctactatg tgactgaaac caaggctagt catggctttg tgaatacttt
     8581 caaaccagta aaagtcgaat tgaattatgt caatcaaaca gtggctcttg ttaccagtaa
     8641 cgtaaaaggg caaaaccaag aaattactgg tgaaaccact ttgacaaaag aagacaaaga
     8701 taccggtcat gaaactcaag ggaaagctga gtttaaaaga gctgaataca ccttgtttac
     8761 tgttaaggat ggaaaagcgg tcaaatggac cgagaacttt aaaccagaat tgttgaaggg
     8821 aacgaaagct tctgatgaaa ccgtaacttt gactttagat gaaaagaatc aagttgccgt
     8881 taaacactta gcgattaatg agtattactg gcaagaaacc aaagcgcctg aaggatatac
     8941 cttggatgaa acaaagtatc ctgtatccat caaaaaggtg gatgatagcg aaaaaaatgc
     9001 tgtgattact cgagatgttg cggcaaaaga acaagtgatt cgctttggct ttgatttctt
     9061 taaatttgct ggatcaacta ctggcactgc cgaaactggc ttcaatgatc taacctttaa
     9121 agtgtcgcca ttggaaggaa ccaatgaaat caccggtgcc gaagatgaag cgaccacagc
     9181 ttataacgag caattagggt ttgatggtta tggcaagttt gaaaatcttc cttatgggga
     9241 ttatttactt gaagaagtag aagccccaga aggttttcaa aagattacgc cattagaaat
     9301 ccgttctact tttaaagaaa ataaagagga ttataccaag agtgattata tctttactat
     9361 taccgaaaaa gggcaaaagc aaccgattaa aacggtaacg gtcccttatg ggaatctaac
     9421 caatgagaat ttctcagtca gtttgaaccg tttgatgctt tatgatttgc ctgaggaaga
     9481 agatagctta acttctcttg cgacttggaa agaaggagat aaagaattga ctactcttga
     9541 ttctaccgag ctagtcgata aattgagcta taatctacat gaaatcaaag aagactggta
     9601 tatcgtagct caagccatcg atgtagatgc tacaaaagct gcccaagaaa aagataaaaa
     9661 agccaaaccg gtggcgattg cggaaacaac cgcaacttta gcgaataaag agaaaacagg
     9721 aacttgggag attctgcata aattaactgt cgaacaagtt ttagacaaga ccattgtctt
     9781 attcaactat gtgtatgaaa gcaaagaagc ctatgaagct ggtgatgagc cggtagcgaa
     9841 ggatgctagc ttgaacaatc aagcgcaaac tgttaattgt atggtggaac gtcatgtttc
     9901 catccaaacc aaagcgcact tagaagaagg ttctcagacc tttactcatg gtgacgtggt
     9961 agatatgttt gatgatgtat ccattaccca tgatgtacta gatggctcaa aagaagcttt
    10021 tgaaacaatt ctgtacgctt tatttccaga tggtacaagt aaagaaattt ggaaatctgg
    10081 caagattgat tacgaagtga atgacaaaga atttaccaaa accgtacttg cggaaaaagt
    10141 ggatacaagt aaatatccag aaggtacaag ttttaccttc aaagaaatta actatgacaa
    10201 agatgggaat atcaatggaa aacacaatga agatttgaaa gaaaaatctc aaactttaac
    10261 gcccaaaaaa gttccgacaa caccaagtac accagaacaa tctgaaatgc caactgttcc
    10321 aagtggctct caagaatcta gtcctacagt gaaggcattc cctcaaaccg gggagaaaac
    10381 ttccaatgtg ctactgttca ttggctttag cttgatcttt gcgacggctg gctattattt
    10441 ttggaatcgt cggaactaag gtgataagat gaaacatgta aatagtagaa aacaatacgc
    10501 gcgaccgcct cctaaaaaag tggtcgcgct atttttgtat tcaaaactaa caatgaaaag
    10561 aggaaaaaat atggaattga aatttgttgt accagatatg gtcgagacgt tcggaaaact
    10621 aacatacggt ggtgaaggtg aagttctatc ggaagggtat ggtcgaaata ctacaattgt
    10681 tggtcgaagt taccatctgt tttcaaataa acaacgggcc gatgatattg aagtggtggt
    10741 agctgcggaa gccggcgaaa aggattttga ccaagatcaa ccactaaaag ctgtaaatcc
    10801 ccacttaatt gccaaaggct atgaaattga gaatcgtggg tttaccgatt acgtgttgta
    10861 tgttgatgat ttagtgaaag cataggagga aaagaagatg agattaacag aaggtattgt
    10921 cgtagattca ggattaacct ttggcaagtt gcgtttttcc gcattacgtc gagaagtacg
    10981 caagcaaaat gaggacggaa cggttagtaa cgaggtaaaa gaacggacct ataatttgaa
    11041 atcctccgcg caaggtcgaa tgatccaagt cagtattcca gcaaatgtac ccttacgcga
    11101 gtttgcttat gatgcagagg tagagctggt caatccaatc gtggatacgg tcgccaatta
    11161 tgtttttcgg gaaggaacca ccgttaattg gtttatcaag gcagatgatt tagtcttgaa
    11221 acgacaactg aatcaaggaa aacctacgaa ccaaaatgaa ggaaagaaat aggtgaagaa
    11281 tatggaaatt aatgttgaac atattttaga ttgtctcgat caatttggca aaggtgagct
    11341 aacggaggaa caactcacta acgcattaac ctatgatgaa aaaatgtttc tgattatgca
    11401 tcaagggtta ctggaagtag gtaacgatgc caaagaagac tttgatgtac tggattggtt
    11461 aggggaagaa gagtctttct ttatggttgt cgaggtaaat gaaagtttat gtcggcaggc
    11521 agaatctgtt ttggaagaaa tcgatgtgga gatgccggat gccatcgaaa gatttttaaa
    11581 acaattagtg gaaacgaaac aacttcccgt agtagtaaat gactagcata actttttgaa
    11641 attgcccaat gaaatcctat tgggcttttt cgactggagg tggaaaccat caaaatgtac
    11701 aaaggacatc gcatacgcgc aggagatcaa cacttgattt atcactttgt tcttggctgg
    11761 ctaatctttt tgttcattgg ttggatgagc gtcttttatt tacaagaact tagacaattt
    11821 gatatttcta aggtatcatt ttccactagt gaaattggct ggtctatgaa ggatgtaatc
    11881 tgcttgctag gaagtctcgc tctttcagga agcatgatgt tactttatat acactttttt
    11941 caggatcatt ggcgaagtct ttggcatcga caaaagttag ctcggatgat tctagaaaac
    12001 cattggtatg aagtaaagca gactcaaggt gaaggttttt tcaaagattt gaatagtagt
    12061 tggaccaaag agagtatcag ttacttcccc aaaatttatt atcgaatgaa agatggctta
    12121 ctgtctattc gcgttcaaat ttcactggga aaatatcaag atcagctatt gaggttggaa
    12181 aagaagttag aaagcggact gtattgtgag ttagtagaaa aagaactcaa agactcctat
    12241 gtggaataca ccttgttata cgatatgatt gccaatcgaa ttgggataga agaaatagtg
    12301 gcagaaaatg gggcgttgcg attgatgaaa aatcaagtat gggcgtatga ttccttgccg
    12361 catatgttaa ttgctggcgg cacaggtggt gggaagacct atttcttact caccattatt
    12421 caagcactat tgaagtcaga tgcagaattg tttatcctcg atcccaaaaa tgcggacctc
    12481 gccgatttag gtacgataat gcctcacgta tactcccaaa aagaagaaat ttctgaatgt
    12541 gtggaagatt tttacgaacg catgatagct cgtagtaggt caatgaaaga aatgcccaac
    12601 tacaaaacag gagagaatta tgcgtatctc ggacttccgc ccaacttttt aatctttgat
    12661 gaatacgtgg cttatatggg tgcgaatcgt tttcctacaa gcatcgaata gatgtgaaat
    12721 ggaagcctat tgagattatc aatagtgaca actaatgttt tgagagatgg aatgaaagcc
    12781 ttcaagttga gctgaaacat ccccgctaat actcctacat gctctaatca atgaagtaga
    12841 ttggttttgg tatgaagcta ggtgaagtcg tctgaaatct gcctaagtgc ttgagcataa
    12901 ggctgactat agggcgggcg gctgaaaaag ataactatgg taagaatgtc tgaaaatgac
    12961 tgacgaatct gcgaatgtac gggtctaaaa ggctgatctt attgaaagat aggaacatac
    13021 ggacgtatgg tgagataccg acaagtaagg ttccatgata tgaaaatcgg gatagctaac
    13081 gaagaagcta taatttcaca ggctcatagt agatacctaa ggttatacat gatagctaaa
    13141 aacattggaa cgatgtaagc agaaaactat caattaaatg actacttcta gataggtgca
    13201 tataagtaat aacgaaattg ctttgtttct gtgaaagtaa gggcacagta ccgatgaagc
    13261 gtctaacaaa tgtggaggga tagccctaag tctatttaat aacaatgaat gttgaaacag
    13321 atgaagttca aggatctggt aagaacgtgg gaaaatccgt tatggaggtg ccacgcttga
    13381 acacaaaaat acgttactgg gaatattatg atctacaaga aacattcgat cagctattta
    13441 ctcaaagtag aaacgggaaa aagttttatc aattatatga gttaatcatt tctgaaaata
    13501 atattctttt agcataccgt actatcaagg caaacaaggg gtcttcgaca ccaggaacgg
    13561 attccttcac aattgataac tataaggaaa tgaaccaagc agagtttatc catcttattc
    13621 tcagtcattt agaaaattac aaaccaaaat ccataaagcg agtaatgata cctaaaccca
    13681 atggtgagaa acgcccatta ggaattccat gcatgattga tcgaatgatc caacagatgt
    13741 tcaagcagat actggagcca atatgtgaag ctaagtttta tgaacatagc tacggtttca
    13801 gaccattgag aagtgcaaag catgctctag gtcgcattat gtatctcata aacatcagta
    13861 aaatgcacta tgcagtagac attgatatca aaggtttctt tgataatgta aaccaccgtt
    13921 tactgataaa acaattatgg aatataggaa tttgtgacaa acaagtctta gctattcttt
    13981 caaaatctct gaaatcaccc attcaaggag aaggtatccc gagcaaagga acgatccaag
    14041 gaggtatcat ttctccacta ttatctaatg ttgttctaaa cgacttagac cattgggtct
    14101 caaagcagtg gcataccttt gaaacaaagt atccctatac taaaggttac aataaatttc
    14161 gtgctctaag agatacaaat ctaaagcaag gctatattgt caggtacgca gatgacttta
    14221 aaatcatgac taatgattat ccgacagcat taaaatggtt ccacgctgtc aagctttacc
    14281 taaaagacag acttaaatta gatatttcca atgagaagtc taaaatcgtc aatttgcgta
    14341 aatgtaagtc ggaattttta ggattcgcta tttgcgtgaa acaaaaaggg aaaaaatggg
    14401 tttgtaattc acgtatttct aacaaaaaaa aggatcagat taaagaagag attaaacaaa
    14461 gaatcaaaga tattcaaaag agtcctacag cacaaaatgc tctcctgttt aatgctctcg
    14521 tgctcggtgt tcataattat ttcaggtatg ccactcatat taatttagat ttgaatagga
    14581 tgaactacgt tctttcattc actacttaca accgattatc aaattgtagt acaagatgtt
    14641 atcccaacaa agcttcccct acttacaaaa agttttactc gacaacgatg aaaacgtata
    14701 aagtagccgg agtctatttg taccctcttt gcgacgtatc tacaaaaaca atttacggat
    14761 ttaatacgga agatacaccg tttaccccgt ttggtcgtca aaggttggag cacaaaagct
    14821 tacaatctct tgtataccaa gaattaagaa aattgatgga atcgaaaata ccgaatagaa
    14881 cggttgagta tttagataat agaatatctc gttactcaat gaaatcaggc aagtgtgaga
    14941 ttacaaaaca gtttttgcca gcaaaagccg ttcactgtca tcactattta ccaaaaagtc
    15001 ttggtggaga cgacaaattt gataacttga gaattattca taaggatatc catcttttga
    15061 tccataccac aaataaaatg ataatcgatc actacgtcaa tgaactgaaa ctgctgccag
    15121 agcaaatagc aaaaatcaac ctttatcgaa aaatgtgtaa tctgcaaaac attcaataga
    15181 aaataaatag atggaacgcc gtatgaggtg aaagtctcac gtacggtgtg gagcggggga
    15241 aaagatggag attatatcaa attcttacct atcgctatag atgttaacga caaaagaaag
    15301 tgcggtgatt ttgaataagc ttaaacaaat cgtgatgtta ggccgtcaat ctggtttctt
    15361 tctgattcta gcttgtcaaa ggccggatgc gaaatatcta ggagatggga ttcgcgatca
    15421 gtttaacttc cgtgtggctt tgggtcgtat gagtgagctt gggtattcca tgatgtttgg
    15481 agaagtcgat aaaaattttt ttatgaaacg catcaaagga cgaggttatg tagatacagg
    15541 gggcagtgtg attagtgagt tttatacgcc acttgtacca aaagggtatg atttcttaag
    15601 ggaaattagc aacattgttg gattaaccgt tcatacggaa agagaaaata atagtgtgta
    15661 gcctaggaat atcaataatc ctgggctttt ttattgaggt gatttatgac atttttagat
    15721 ttattcgccg ggattggtgg ctttcgctta ggtatggaac aagccggtca ccagtgtatc
    15781 ggtttttgtg aaattgatga atttgctcgg aggagttata aagcaatcca tgatacaagg
    15841 aaggaggtgg aaatgcatga catcacaagt gtatcagacg aatttgttcg atccctcgga
    15901 ccagtggaca tcctttgcgg cggctttccg tgccaagctt tttcaattgc gggaaagcgg
    15961 caaggatttt ccgatactcg aggtacttta ttctttgaaa tcgctcggtt cgccactctt
    16021 ctccaaccta agtttctatt ccttgagaac gtccggggat tgctcaatca cgaaggaggg
    16081 gctacgttcg agacgatcct ccgaacgttg gatggattgg ggtatgatgt ggaatggcaa
    16141 gtgcttaact caaaggccta cgttccccaa agccgtgagc ggatcttcct tatcggacat
    16201 tctcgagatg catgtaccga acaagtattt cctatcattg gatcgtcttc aacatctgat
    16261 caaaacatca gaaacttggt aaatatcaat ccttccaatc gaggaatggg tggccaagtc
    16321 tatggttcag atagcgtagc accaaccttg accggtgatg aaggaattaa aattgcctta
    16381 ccggtaaagg atgggatttc tgtagcgggt atgttgtcgg gaaattttga acaaggcaat
    16441 aggatttatg aggtaaccgg aacagccccc actttgtcaa cgaaacaagg gggaacgaag
    16501 attatgattc ggaaaaatga aacagaatat caagaggtga agccagggga cagtgtgaac
    16561 ctggcttttc ctaattccac aagtcgccga ggtcgtctgg gaaaacaaag tgtgcatacc
    16621 ttactaacag gagaccaaca agcggtagtc acggatcagt accagattcg aaagttaaca
    16681 cctagggagt gctggcggct tcagggcttt ccagattggg cttttgatcg agcttctcaa
    16741 gtcaattcag atagtcagtt gtataaacag gccggaaact cagtaacagt tccggtcatt
    16801 tttgatattg ctagaagatt aaagggggta aaagcatatg atttatgacg agttgattgg
    16861 agaaatctac tgggtgattg gcaagattca ggcagatccg aaattggaag aagaactgta
    16921 ccggctcaat tttgatattc gcaaaaacgg ggtgaaagtc caggtgattc gtatgtagtg
    16981 gatgaggaaa cggatgctcg aatggagctc aatcaagtca tcggtgaatt ggaacgaatt
    17041 gcggaccttg ccaaagaacc tgatatccgc caatacttgt ttgagataaa agcagagttg
    17101 gaaattgagg gtatcaccgc ggagtaatag ggaaataacc cactgatagg cactgaccgc
    17161 gggggatttg cgaagcagaa atcctccgtg gtgctgtgcc tgttcatgga cggcggcagc
    17221 cggccatgat gtctcacccc ccgtatctaa caggggggta caaaaacaca aaaaacaagc
    17281 aagtaaccat aaaaaatgct tgttgtatca aggatattaa gtaatttgta taggtgttaa
    17341 ctcatttgga aaagttaaca ccttgaattt ggaggtgaaa acttggcgca acgaaattta
    17401 gattatcggt tattaaaaga acgacgcaac gaatatggcg tttcacaaaa taaattagct
    17461 actgcttgcg gacttagccg cccataccta aatcagatag aaaacggtgg cgtaatcgcc
    17521 tctacaaaga ccatgagaaa aatttttgat caactggaaa gtttcaatcc cgatttacct
    17581 ttaacgttac tatttgacta tgtaaggatt cgctttccca caacggatgt gcggaaaatt
    17641 attcaagaaa ttctccattt gaaattcgag tatatgcttc atgaagatta cgccttttac
    17701 tcctatcaag aacaatatgt catgggcgat attgtagtga tgttatctca tgaagaagat
    17761 aaaggtgtcc ttttggaatt aaaaggtcgt ggttgccggc agtttgaaac ttttttactc
    17821 gcccaaaagc gtagctggta cgactttttt gaagattgtc taaaagccgg tggcgtgatg
    17881 aaacgcttgg atttagcaat caatgatcga gtggggctac tggatattcc tgatttaacg
    17941 aaaaaatgtc agaaggaaga atgtatctcc ttgtttcgta ccttcaaaag ttaccgttcc
    18001 ggggaactgt tgaaagctga tgaaaaggat ggtatgggca ataccttata tattggcagc
    18061 ctcaaaagcg aggtttattt ttgtttgtac gaaaaagatt atgaacaata tatcaagtta
    18121 gggattccat tggaccagac cgaaacgaaa aatcgttttg agattcggtt gaaaaatgac
    18181 cgtgcttatt atgcgattca agatttgtta aaaggtcgta gcattgaaag taccacgttt
    18241 tccattatca atcggtattt gcgatttgcg gataaagtag atggaaaacg gcgaaccaat
    18301 tggcccttga atgaacaatg gggtcgtttt attggacgga atcggaaaga gattcaatta
    18361 acttctgaac cgaaaccgta taccattgaa cgaacattaa attggctagg tagacaagtc
    18421 gcccctacgt ggaaaatggc taaggagttg gatcgattga atcaaacaac gtatatccag
    18481 gatatggtac agaatgcgcg actctcggac cggcataaaa agattttgga gcaacaaagt
    18541 atggcaatcg aaaacttgat tgtatgaaaa gaggaatttt gatggaaatt gtaaaagata
    18601 tgttattggt acttggtggc agtatgcttg gtgttaccgt gatgtgcttg atgaatgcaa
    18661 gtgcagcagc ggattgagca atggaaaaga aaggaaagtg acaaaatgaa tttcggacaa
    18721 aattt
//
LOCUS       DAXQKX010000052        16865 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.053, whole genome shotgun sequence.
ACCESSION   DAXQKX010000052 DAXQKX010000000
VERSION     DAXQKX010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16865
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.053"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(179..586)
                     /locus_tag="ACF3MF_002031"
     CDS             complement(179..586)
                     /locus_tag="ACF3MF_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HFE3927993.1"
                     /translation="MKFLRKAGVKIGDVIIIGILIIPSFIPLFVFSIEKENETTEDAI
                     KYAIVQIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVR
                     TGWISKPGQTSICLPHKLVISIEKKESKDYYIY"
     gene            complement(775..1785)
                     /locus_tag="ACF3MF_002032"
     CDS             complement(775..1785)
                     /locus_tag="ACF3MF_002032"
                     /inference="COORDINATES: protein motif:HMM:NF014542.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFE3927994.1"
                     /translation="MPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVNVDG
                     VLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGISKPI
                     PIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVVEEE
                     QDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVDLSK
                     ILNTNLFNIDETSYSMGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFAHLT
                     DKNFPGNITRAKGFLWFAQHSDFSTIFETSGSHKSIESLNYWVASLPKIECQMIIQKN
                     PN"
     gene            1911..2129
                     /locus_tag="ACF3MF_002033"
     CDS             1911..2129
                     /locus_tag="ACF3MF_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3927995.1"
                     /translation="MSQYCHLTILKRERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTNHLPKRKKIMLIEEKNADVITF"
     gene            2222..2785
                     /locus_tag="ACF3MF_002034"
     CDS             2222..2785
                     /locus_tag="ACF3MF_002034"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFE3927996.1"
                     /translation="MDFSISFITIYRAICNDLFDTEPLSHGNKGLIRSLHHRGKTRHT
                     KNHVESRGKICLTHSIHGHPKSADDRSDFGHWKADIVAGKTSGTCLVTLTDRKSCFLL
                     AGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITPDRGKEFSNHFAVTEVLNNMPFYFP
                     DPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(2978..3217)
                     /locus_tag="ACF3MF_002035"
     CDS             complement(2978..3217)
                     /locus_tag="ACF3MF_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3927997.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYQFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(3241..4764)
                     /locus_tag="ACF3MF_002036"
     CDS             complement(3241..4764)
                     /locus_tag="ACF3MF_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HFE3927998.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLIQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKLNKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNEMHNWPTFYPASLSEHEIAQEMMAH"
     gene            complement(4782..4904)
                     /locus_tag="ACF3MF_002037"
     CDS             complement(4782..4904)
                     /locus_tag="ACF3MF_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HFE3927999.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKQNKMKKLA"
     gene            complement(4934..5917)
                     /locus_tag="ACF3MF_002038"
     CDS             complement(4934..5917)
                     /locus_tag="ACF3MF_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFE3928000.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVIADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLEKFNHPLVFESDSSENH
                     YNGKHYHQHHQEHEFKSILLTSDQDIKKDFLFQLIDRLILTNQGSLYRFKGLIALQDQ
                     DFIVAIQGVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            complement(5941..6090)
                     /gene="rpmG"
                     /locus_tag="ACF3MF_002039"
     CDS             complement(5941..6090)
                     /gene="rpmG"
                     /locus_tag="ACF3MF_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFE3928001.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            complement(6111..6488)
                     /locus_tag="ACF3MF_002040"
     CDS             complement(6111..6488)
                     /locus_tag="ACF3MF_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928002.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            complement(6520..6699)
                     /gene="rpmF"
                     /locus_tag="ACF3MF_002041"
     CDS             complement(6520..6699)
                     /gene="rpmF"
                     /locus_tag="ACF3MF_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HFE3928003.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            complement(6714..6983)
                     /gene="rpsN"
                     /locus_tag="ACF3MF_002042"
     CDS             complement(6714..6983)
                     /gene="rpsN"
                     /locus_tag="ACF3MF_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFE3928004.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(7506..9272)
                     /locus_tag="ACF3MF_002043"
     CDS             complement(7506..9272)
                     /locus_tag="ACF3MF_002043"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3928005.1"
                     /translation="MQMIGGLTMKSFYKNKFALTNQGAEDLVKASISSFFVYCINMVP
                     AFIIMMLIDELVLENVKPPWLYFTVSFVTLLFMYWLLDREYENLYNSTYKESAHLRMQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKIVDQGTHSELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(9232..10986)
                     /locus_tag="ACF3MF_002044"
     CDS             complement(9232..10986)
                     /locus_tag="ACF3MF_002044"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3928006.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVEDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(11096..11665)
                     /locus_tag="ACF3MF_002045"
     CDS             complement(11096..11665)
                     /locus_tag="ACF3MF_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HFE3928007.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(11683..13098)
                     /locus_tag="ACF3MF_002046"
     CDS             complement(11683..13098)
                     /locus_tag="ACF3MF_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3928008.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            complement(13109..13777)
                     /locus_tag="ACF3MF_002047"
     CDS             complement(13109..13777)
                     /locus_tag="ACF3MF_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T"
                     /protein_id="HFE3928009.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFGTSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(13908..14492)
                     /locus_tag="ACF3MF_002048"
     CDS             complement(13908..14492)
                     /locus_tag="ACF3MF_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFE3928010.1"
                     /translation="MESGLSHFEKVGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLV
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(14823..15056)
                     /locus_tag="ACF3MF_002049"
     CDS             complement(14823..15056)
                     /locus_tag="ACF3MF_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HFE3928011.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLTKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(15071..16021)
                     /locus_tag="ACF3MF_002050"
     CDS             complement(15071..16021)
                     /locus_tag="ACF3MF_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein"
                     /protein_id="HFE3928012.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSTNSKDKDTVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(16018..16860)
                     /locus_tag="ACF3MF_002051"
     CDS             complement(16018..16860)
                     /locus_tag="ACF3MF_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HFE3928013.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVTVVLFFKELLIT
                     SFDPLMAKAMGMNVSFYHYLLMILLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGACSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERKL"
BASE COUNT         5442 a         3175 c         2337 g         5911 t
ORIGIN      
        1 aaataagtaa tctaaccgac tgttaactaa accattgcag gtcccgttaa agatacttgt
       61 gcctgttgtc accgcttctt tttcttgtcc acaagcgctt aacacactta ataaagcccc
      121 tgctattatt aataataata tctttttctt attaaaaacc tcctcatcta tttccagatt
      181 agtaaatgta gtaatctttg ctttcttttt tctcaatact aataactaac ttatggggta
      241 aacaaatact cgtttgaccg ggttttgaga tccatccagt tctaaccgcg atttgatcag
      301 gactattatc ttctttaact cgaattcttc catctttaat ctcaacaata ttatattgtc
      361 ccttcgcagg atgataattc acgagtttat gattgatctt atccaaatcg aagcgatcca
      421 tttccttgcc atcaatttga acgatggcat atttgatagc atcttcagtt gtttcattct
      481 ccttttctat agagaataca aataagggaa taaaagaggg aataatcaaa atgccaataa
      541 ttatgacatc gcctatcttg acaccagctt ttcttaaaaa tttcattaac gatatctggc
      601 taaacatatt agaatttttc catggaaatg gtgaaatttt tcggaaatta tctgcattaa
      661 gagaatcagt taaacaaccc tcaagttgtt ccttaataca ttgttgatcc atcttcatac
      721 caataaaaac tagtttatta atgcgttcac caaacaacgg atgccaggct tccttcaatt
      781 cgggtttttt tgtataatca tttgacactc aattttaggt aaactagcta cccaataatt
      841 taatgattca atacttttat ggctacccga tgtttcaaag atcgtcgaaa aatcactatg
      901 ttgggcaaac caaagaaacc cttttgctct tgtaatattg ccaggaaaat ttttatccgt
      961 aagatgggca aatttttgtg cgtcaaggag taaccgattt cgatagataa aacttgagat
     1021 accatattct tctgtttcag gaatatgatt ttgatagcca agctctaact ctttgaacca
     1081 gcccattgaa taggaagtct catctatatt aaaaagattt gtatttagaa ttttcgataa
     1141 gtctacttca cctttaattg tcctaattat tttggcattg gactgtaact tagcaattag
     1201 accgttaatt ttgtaaatcg tcttggttga cactaagtca ctattattta aaagtaatat
     1261 gttacaacac tcgaattgat caattaacaa gccacgaata tcctgttctt cttcaactac
     1321 attaccttca gcttttcttt cctgaatctt ttcacccgtt tcgaaattat cccaaaaacg
     1381 ttttacatcc actactataa taatggcacc aatctctaat cgttgggtca aatcaatgtc
     1441 taaagggttt ttagctaata taattgcttg aataattgga attggtttgc tgattcctga
     1501 agcttcaata acaatttgat tcaagtcaga aaattgcact aattgatcta gttcaacaat
     1561 caaatcttcg cgtaatgtac aacaaatgca tccattcggc atcgaaacaa gtttttctcc
     1621 agttctttta aaacctttct tgtcgactaa taccccatca acatttactt cccctatgtc
     1681 atttacaatg acagcaattt cctttccgtg atcaccgtac agaatatgat ttagaagtat
     1741 cgtttttcct gaaccaagat agccagttaa gattgtaata ggtatttttt catagggaac
     1801 ctctttctat accttgaatt tacactttaa gtgcaacaca taaaaatgag tcataatcga
     1861 tatccaacta gtataagttt gtcgagaaca ctcctagaag gaaaataatt atgagccagt
     1921 attgtcatct tactatactc aaacgagaaa gaatctttct gcttcacgaa gaaggatttt
     1981 ctattagtat aattggcaac gacattcagc atagcccgtt tactatttta catgaactga
     2041 gaagaaacaa gaaaaaaact aatcaccttc caaagcggaa aaaaattatg cttatcgaag
     2101 aaaaaaatgc ggacgttatc acattctaaa tgatccgtga gtttggtcaa ttgttcgtca
     2161 tttatttgtc gattttcagt ggtcgccaga gaaaatctcg aatcgtttga agcatgaaca
     2221 tatggacttt tcaattagtt ttatcacgat ctaccgtgca atttgcaatg atcttttcga
     2281 tacagaaccc ctctcacacg gcaataaagg cctgatccgt tcattgcacc atcgaggaaa
     2341 aacaagacat acaaaaaatc atgtcgagtc tcgtgggaag atttgcctta ctcattcgat
     2401 ccatggccat ccaaaatccg cagatgatag aagtgatttt ggtcattgga aagccgatat
     2461 tgtagctggc aaaactagtg gtacttgttt agtgactttg acagacagaa aatcatgctt
     2521 ccttttagca ggaaagaagg tccccagaaa gaaagccgct tatgtgagcg agaaaatgat
     2581 tgaactttta agcagtattc caaatgaggc ggtcaaaacg atcactccag atagaggaaa
     2641 agaattctcc aatcatttcg cagttacaga agtattgaat aatatgccct tttattttcc
     2701 agatcctcat gcccttggca acaatgaaca aattaaaata cgaatagact cattcgagaa
     2761 tacttgccaa aatcgaaaga gatagctacg gtagataact caacgataaa tcagatgatt
     2821 gaaaaactga ataacagacc tagaaagtgt ttagattgga gaacacctta tgaagtcttc
     2881 tttgataaag tgttgcgctt gatttgacaa ttcaagaaat aataaaaagc agatcaaatc
     2941 caaataaggg aaaaatgatc tactctggta ttatcaatta attggccaag ctattatgcc
     3001 gttttgctaa acgtctactt cttccagtat tgaccttgat aaaacaacaa tcaggatccc
     3061 gttttaatac tctatgaact gtgtcaatac taacatgtaa agttgcagca atatcagcta
     3121 atgtactccc atttaatctc atttgctttg caaattgata acgccgataa gcatcaatat
     3181 tcttggaatc catagacaat aatacttttc ttaccatgta tttcctccaa agattggatt
     3241 ttaatgggcc atcatttctt gagcaatctc atgctcagat aatgaagctg gatagaaagt
     3301 aggccaatta tgcatttcat tataaagttt ttcttgactt tctccaccaa agaaaatatg
     3361 gaaatgctct gccttacttg gtgcaattcc atgatcgcta aattgaatat atttaaaacg
     3421 accagcacct gcatcatcag tttcaaaatt aaaacgaaca ccacggtttc ctttttcata
     3481 attcaaaatt ttgtatccaa catatttgta tgtgtattga tgatgttcac cgttgactac
     3541 aaaatcaatg gtgttgtctt taatgttgat agtatcaata tctgtcttat agccagtagt
     3601 ataataatct ttgtactcgg cagctgtcat gtctttattg agttttgctt tgtaatcgaa
     3661 aacttcatcc aaaattccat cttttaacaa cggataaaca gattgccatt cgcctgtata
     3721 atcactcaat tcgcgatcct tcacatcggc atctttaaag tacccattag caactgtctt
     3781 ttcatccttc gcttcttttt ctggaactac ctcttcacca gcaaccatag ttgttttctc
     3841 taacgctttt agattgtctt ccattactga aacataatct tcaccattat ccatttgttc
     3901 ttttgtaaga ctttcaagag gattcaatac ttccaatttt atcccagctt cattggccaa
     3961 agtttttgcg attttatcat tagcattctt ttcaaagtaa atataattga tcttattttt
     4021 tttaacatac tcttttaatt cagctaatcg accagaagat ggctcttctt caggacttag
     4081 tccagcaata ggaacttgta tcaatccata atccaaagct aaatatccaa aggctgcatg
     4141 ttgtgtcaca aaactttttt gtttcgcttc tttaagacta gtggtatagt cagcatccaa
     4201 ccgtttcagt ttagtcaaat acttttcagc atttgtctca aatacttttg cttttttcgg
     4261 atacaattta actaactgat ccttgatatt tgaaacttcc ttaattgcca ttttgggtga
     4321 aacccacgta tgaggatcta gttcatgatg gtgatcttct tctccgtgat catgatcttc
     4381 ttcttcacta cctggcaata aaatcatgtc ttttgttcct tctactacat taggcccagc
     4441 tttcttccaa ctttctttag cttttggtac ccatgattcc atgttttcgt tatgatatac
     4501 aaaaacatca gcatcatgag cttttgccat atccttagct gagggctcat agtcatgagg
     4561 ttctgatccc gctggaacca ttaaatccac gttcgcttca tcgccgacga tgtttttggt
     4621 gaaatcatac attggataga atgttgttac aatttctaat tttccatctt tatcattcga
     4681 tacttttgca tcattagtgc tggagcaagc tcccaataat cctagagctg ctatcccaat
     4741 aagtcctaca ctgattttct tcattctttt tccttcctta attatgctaa tttcttcatt
     4801 ttattttgtt tatgttcttt gataattttt aatgcccttt ttctagtttt gatattcggg
     4861 cttttaagtc gtcgatatgc actagatata tccgttttct ccattagaaa ttacccctaa
     4921 tcaatactta tcattatttg ctttccgcca gtaatttatc aaaactctgt ttgatccttt
     4981 cttcatccaa catttttcca attagaataa tagtggtttg gtctttttgt cgagtggtgt
     5041 attgaaaatt aacctgttcg tttacccctt gtatggcaac tataaaatct tgatcttgca
     5101 aagcaatcaa tcctttaaaa cgatacaggc tcccttggtt ggttaaaatc agccggtcaa
     5161 ttaattggaa taaaaaatct ttttttatgt cttgatctga agttaagaga attgatttaa
     5221 actcatgttc ttgatgatgt tgatgatagt gtttgccatt atagtgattt tctgatgaat
     5281 cactttcaaa aactaaggga tgattgaatt tttccaaatt ataaaaatcc tttttttgaa
     5341 tcgtttcact atgtgtgaac attcgaatat cggataaagg gttaatactt ttgatttctc
     5401 tctgtaattt ttttagtgca gataaattca agttttgttt tctagacaca aaaatgcgat
     5461 ctgctatgac aagttgctta agggcttgtg gttctctttc aataagttca aaactgtcac
     5521 tatcaataac agtcaataaa ctatcgatat atactcttcc tcttagttga ggcgctgtta
     5581 aaagtgtttg aatgattggt tggggatctg ctatacctgt agtttcaatg atgatttgtg
     5641 aaattggttg ttgatgttct tctattgttt ccagtaaaga aatcaatatt gctaataaat
     5701 cactgcgaag actgcaacac atacatccat tatttagttg taacacccgt tcctcgctat
     5761 gaactaataa tttgtgatca atcccaactt caccaaactc attttcaatt ataataattt
     5821 cttccctggg gtagggtgag acttgcaagg cttgattgat tagcgttgtt tttccagccc
     5881 ctaaaaaccc agaaacgatt gtaactggta tgcccatttt gtcacctttt taccacttag
     5941 ctatttcact tctttgaaaa ttgcccgtct gcgcaatttt ggcgaatact tttttaattc
     6001 taaccgttca gggttattcc gtttattttt gctggtgaga tacagacgtt ctccagtttc
     6061 gacacattcc aaaataatat tttgacgcat aaatcttcct ccttcaatac ttatcgatct
     6121 tcaagatatg cttgaatttg ttgtgcatct tcaaaagtta actcgccaga ttccaattgt
     6181 gaaactaaat tttctttcat atcaacaggt atctcccaat aaccatcaat acattgaaat
     6241 aactcctcgt catactcttc aaaaattgga tagattctta aaaaatcatc aaatgataag
     6301 ccttggtcct catagtaatc tttgactaat ccattttcaa ttgcctgttg ggtcggtaaa
     6361 cccgtttcag taataattcc tctctctacc atcgaacgat aaaaagtgca tttatctagc
     6421 gattgctggg tcgtttcaag ataatacttt aatccttctt caactaaagg tgggtaaata
     6481 atttccattt tgattccctc ctaaaagtta tatattaaac tattttgaag ctcctttaat
     6541 tactttcttt ccattatagt acccttttaa agatacatga tggctacgtc tataatcacc
     6601 attcgcttcg tcaaatgaaa tttctggttt tactacagtt tgatgagttc ttcttaaccg
     6661 tttcttcgcc ttagatgttt ttcttgctgg tactgccatg atatttcctc cttttaccaa
     6721 cttgcttttt ttactccagg aatcaaccct tgatgggcaa gttctctaaa cttaatacgg
     6781 gacataccga actttcgcat ataccctctt ggacgaccat ccgtctgatc acgaagcctc
     6841 agacgattcg gatttgaatc tcttggcaat ttagcgagag cggtgcgatc tcctgcggct
     6901 tttaattcct gacgtttatc tgcgtacttt tcaatcatcg ccatttgttt ctttgcttta
     6961 gcaattttcg acttttttgc catatacctt tatactcctt ttattttgat ttagacatct
     7021 caaatcgtaa tcgttacgtt ttgacactga tactttacca acaagagttg ctcttgtcaa
     7081 caataaataa catgaaataa aactcatatg aatagataac tatttgaaaa cgaatttatc
     7141 ggtacataga gataatcaaa tcatttaaaa gaatatgcag tttaagctct gaaaaataag
     7201 aattcacttt tattagtcca atcaaacaca aataccgttt taagtagctt ttcctctact
     7261 taaaacggca atatgaaaga aactataact ttttattcaa tcttttatgt ttaactggtt
     7321 tatcgccaat tttttaaaac tttgattatt ccttatatta taagaataga cattaagtga
     7381 actaattcaa tcatactgat tctttcgtgt attcaaaatt agatgctgtt taataaaatt
     7441 attctttttg aaaaagaatt ataactatat cccaaaaatt gtaggttaat ttaaagccta
     7501 tttcatcatc gtgattgagc ttctttttca tagacgaatt tctcagatag tttagttttc
     7561 tttatgagat ttttgtatat ttctgacctt cgatacaact cactatgagt accttgatca
     7621 actatttttc cttgatccat cactacaatt ttatttacct tttcaataga cttcaagcga
     7681 tgcgatataa ttagtactgt cttatcttgt attaaacgat ttaaactttc ctgaatacgt
     7741 ttttcatttt ccgcatctaa actggcagta atttcatcta aaattaaaat tggcgcattt
     7801 ttcaaaaaag cccgtgctat ggataggcgt tgtcgctctc ctccagaaag tgaacttccg
     7861 ttttctccga ccaatgtatg ataaccgtca ggtagttttt caataaagtc ttcgcagtta
     7921 gctaaacgag ctgctttttt cacttcctca tctgacgctt gactatttcc aatacgtata
     7981 ttttccaaaa tacttgtatt aaacaaagtt acctcttgaa aaacaatagc gattttgcta
     8041 aacaaagaag ctggagatac acgtttaata tcatacccat caattaaaat acagccttca
     8101 tcataatcat acagtctaga cactaatttc aagatactag ttttcccgga accactagca
     8161 cctactaacg cagtcacttc tccttgttta gccgtaaaag agatatgatc taaaattggg
     8221 gtattgttat catatgagaa agagacatct cgcaactcaa tgtcaaaaga tttcagagga
     8281 ctatctgatc cctcttggat actggtttcc ttcatagctc taattcgctg tattttagga
     8341 gctaaataaa atatttcaag cactgcttct ttcatagaat cgaaggaatc ctttattttt
     8401 attgcggcta gtaagtaacc aacgacgtag agtatagtca cttcacccgt taacagtaag
     8461 tgaacaccta ctagaatgac tactgctaaa ctaacatatg agaaaataga ggataaggcc
     8521 atgactgaaa aagtacttaa ttctaccttt aaatgaatcc tttcactctc ttccattttt
     8581 ttgaaaagtc tgtcttgaac ttttttagat agattaaagc tattaatctc ttgctgcaat
     8641 tctatagttt cttgaaattc ttccgagttt tctctcaaag tatcgtaata tttagtattg
     8701 gctttcgttt gggatttctt tgataacaag attaagacaa aactaaataa cgttggcaaa
     8761 ataacagcta atcccatttt gacattacca accaaaagca tcactgaaat aaaagggaaa
     8821 aacagagcca taccgccggc tttaggtatt gcatgactca tcgcatgctc aataccttca
     8881 acgtcagaca tgatagtttg agataaatct gataaattat gttttgaaaa ataggataat
     8941 ggtaaatttg acaaatcgtc tgcaatttgc attcttaaat gcgcactttc tttataagta
     9001 ctattatata agttttcata ctccctatct aacaaccaat acatgaaaag caaagtaacg
     9061 aacgatactg taaaataaag ccaaggcggc tttacatttt ctaaaactaa ttcgtctatc
     9121 agcatcatta taatgaatgc tggtaccata ttaatgcagt atacaaaaaa gctagaaata
     9181 gatgctttaa ccaaatcttc tgcgccctga ttagttaaag cgaatttgtt tttataaaaa
     9241 cttttcattg tcaagcctcc aatcatttgc attctcataa ttagtgacca attgtttata
     9301 cacttgatgt ttagccatta attcattatg atttccacgt tctactattt tcccttctga
     9361 caagacaaga atttcatcta cagatttaat gctggataat cgatgagcta tcataataac
     9421 tgttttttct ttcatcagat gttgaaaagc cttttgtagt tcatactcat tatctggatc
     9481 aatagatgca ctggcttcat ccataataac aatctttgca tcttttaaaa ttgctctggc
     9541 aatagctata cgttgttttt ctcctcctga cagataaact cctttactac caattaaggt
     9601 atgctctctt tcgggaaatt tttctaaaat cgattcgcaa ccggctaatc ttagcgcgtc
     9661 aaatacttta cttgctggcg cttgaggatt tgctatagaa acgttatcgt aaatactctg
     9721 attgaatagt ttcgtatctt gaaagacaaa agcaattgtg ttaataattg tgtcttttga
     9781 atagtgattt aaaggcttac caccaatttt aatctgtccc ttatccacat tgtagaaacc
     9841 tgaaattagt ttagctatcg tactctttcc gcttcctgat tttcctacta atgcataaat
     9901 tcttttttgt tctaaaacta agttgaaatt ttctaaaaca cactcttctt tgtatgaaaa
     9961 gctgacattt tcaaatgcaa tgtcacaatt tttaatctgt gtctcgttcc catattttag
    10021 ttggtcttgc ttcatttcta aataaaggga gtctagtgtt tcgactgcat atcttgcttc
    10081 aaacaagtgc atacttacat acattattct catgaaagaa acaaaaataa ttccacttaa
    10141 aaaaaacaac atcaacaagt caacagctaa tatcttggga gtggtaagag aagttataaa
    10201 aaaggttata ggaactatca aaatgcaaac tatgccaaaa aatagccatt gaaaaagaac
    10261 aaaaggtgtt ttcccactca aagaatactt atatgcaaac ttagcataat cgttaattgc
    10321 tttattcaag gctttaaatg atgttacttt agcaccaaat atctttataa cttgaattcc
    10381 gcggatatat tctaccgttt cagagcttaa cacatctaac gattcttgat atttttgaat
    10441 aaaatttgta ttctctgtca ttttctttaa caagaataca ccaattacta acatggcgat
    10501 tagaaccaat ccaattttaa agttaatgaa aaagcctaag gcaactgata aaacaggtgt
    10561 tactatggct tgagcactat ctggaatcaa gtgagcaatt gccatatgtg ttttagccgc
    10621 gttgtcatca attgtctttc gaatatatcc cgaagaattt aaatcaaaaa aacgaaaact
    10681 tgcttctgtt aaaccgctaa ttcccttttt tctcaaatta gtctctaagc gaaacccaag
    10741 gatatgagaa aataagccag aaaaaatata aaataaagct cctaaagtta accaagcaac
    10801 agtttgaacc gcataactct tagctaaata ttcatcttct acaataatta gagactgaag
    10861 aaatttgtaa atactgtaat atccatagac tgttaatacg acagaaaaat cagaaaataa
    10921 agtggctaac catccgtagt atttcatttt agggacataa ctaaataatt ttttgtatac
    10981 tttcattttt tcctcccccg cattcaattt cttctcttat tcgtttacaa ctgttaatgc
    11041 tttccgtaat agcgtaaatt agagatgtac aaacagatag aaggtaaact acgttctatt
    11101 ttttgtattt ttttaagact tttcttccaa tcaatacacc aatcatagat aaacttgcta
    11161 caactaacac tgaaatgatt ccccatatac ctaccgcata gtggatcatt gcatccattg
    11221 ttgcagcaga ttgtccttta tctatccaat cttgacgaaa acgatctgta aagaaccata
    11281 taggaatcca ctgtccggca gcactgccta attgcattag agcccaagac gcaacttgag
    11341 gaattgctcg atcatatcca aatacagata gaataatatc agctaagatc gccatactaa
    11401 tcgaactgat aaaccaaggt aagtacgccc cgcccattaa cgtaaaaaat aacaataaaa
    11461 caattgtgta aatagtaaaa attccttttc tagggtagtt atagctaata taaacaaata
    11521 tgattccaga taataatcca aaaatccctg gggatatgct gtgaccaaac gccccaccaa
    11581 tactactaac cattattgaa aaaaagtaaa ttactaggga aataactgta gctaaaccaa
    11641 taaaaatata atcttttgtt ttcatatata ttctcctcaa ttctatttcg ttatgtcatt
    11701 aaaaatctgt tctatcaaag ttgaatcttc tactctaagt tttatatctt tttttattcc
    11761 accatttttt aaataaataa ttctattgca tgttttataa agaaattccg gatcatgagt
    11821 ggctataact actgcaccct tttcttttaa gtctttaata aggtcagcaa tcctttccat
    11881 attgatataa tccaacccac ttgtaggttc atcaaataga aataaattag tttttgacaa
    11941 tgaagctata gaaaccaata atctttgttt ttctccaccg gataaatcaa acggtaattg
    12001 atctttcatt ttataaagtt ccattttttt taaaattttt tcttgctgat ctttactaac
    12061 tatttcattc cccagggcta actcgctcct cactgattct gtgaaaaatt ggtaatccat
    12121 ttcttgcatt actaaaaacg gcgatgacaa atttttttta ttttcgatta tctttccttt
    12181 ggtagggcga ataatcttca tgagtattct tagtaaggtt gttttcccca caccgttttt
    12241 ccctaccaaa ccaataacat ctccaacttt gacatcaaaa tttatgtctt ttagaatatt
    12301 ttcataagta atttcttcaa cttttaatac atctgcactt accttttcga tatagggaac
    12361 ttcaatcgaa ctattaaaaa tgtcaaattt ccttaatgcg ttattgtttt cagtttttaa
    12421 caactgaata gttgtagttt ttacagttct atttttaaca aatagaactt gatcaattaa
    12481 ttctttcaaa tagtaaaaac gatgttcagc tataacaata gtaaatcctt tattttttaa
    12541 atcacaaagt aagtcagcaa gtttcttagt cgctttgaag tccaaatttg aagacggttc
    12601 atccaatata attaatttag agtttagcga taaactacat ccaatagaaa ttttctgccg
    12661 ttcaccactt gatagcgaaa aaatgttttt atctaatata tttgaaagat ctaataattc
    12721 agctaattca ttgattcttt tatccatatg ctcttttgta aatccaaagt tttccatcga
    12781 aaatactaac tcactcgttg tatttgttgt aaagaattgt cctctaggat cttgacttac
    12841 gtagccaata ttttttgata tactttcttg tgttaaggat tgtagcgagt tattttcaaa
    12901 taaaatttcc ccaaccaatt ttccgtcata aagtcttgga ataagtccat tcattaactt
    12961 taatagtgtg gatttcccac tcccagaaga accagtaatc aatgtaagac tacctttttt
    13021 tattgaaaaa ttaaggtcaa caagcgcttg ttccttaaca tccttatatg aaaaagaaac
    13081 attgttaaat tcaaacaatt ctttcacctc aaatcaaaat acttaagaaa aaaatagtaa
    13141 cggaaaacag gatgatatag tctaataagc tcatgtttgt tttatagtaa gaacttcttt
    13201 tcacaggaga ttctatcccc tttgttattg cattagcggt catttcttca gcaatcatag
    13261 ttgcacgtat aagaacggga actaacagaa attccaaata ttgcagaggc tgaaaaaaag
    13321 acaagcgaat gtttctcatt tttaaagatt ctttaatcat tcttatttca gaacgataag
    13381 tcggaaagaa tctgatcact actgtaatac ttaacattat ttttttcggt aaatgtattt
    13441 tttctaaaga ggataataat tcattgctag tatagacact aaccaacaac catgagatca
    13501 ttacgaccgg caacattcga aatacaatat ataaggatgt cccaaaaaat atagtaaaaa
    13561 actctatctt gatagcatca ataattttca ttactaaaaa cagaactgaa taaatcaaga
    13621 tgaaataaat acatgtcttt attttacgaa acatcaatac taaaactgta gcaataatga
    13681 aacaccccac ttgaaatata tttccctttc ctaaaaaaat aatgaccgga aaaaaaatat
    13741 ttaaagtaat caaggttaac ggattgattt ttgacactct ttcacctcca aaaaataaga
    13801 tcgcactgtt atcttaagct gataaaaatg caccgttatt cagataacag tgcgatctta
    13861 tcaaaaagca taactgagaa caattctcaa tgcaagcttt tttttaatta actcagtaat
    13921 tcaatccacc caggaacaga aaattgatac aatcttctgg ttaatagcat agtcttttct
    13981 tttgaatagc tatgcttcaa tatatcatag aatgtagcgt agaatgagta aatgtagaag
    14041 tggatttctt cttcattaaa gactaaattt tgattgatca ttccgatagt ctttaactta
    14101 tctagacaac agactgtctt ttttgtcaca aatgatgtaa ttttttcaac aatatcttga
    14161 tatttggttc cagctgattg gaataaaacc aaatcgaata tacgtttatt ctcaaaaata
    14221 taattaataa atggatctaa ttcattgaag ttctctctcc aacttttctc tatatctata
    14281 ttttctaagt ttaagaggta tttggtaaac tcttcattat acatattaat aagcgcatta
    14341 atatgcggct gaataatttc ttcaaataac gcttccttag aagtaaaatg tttataaaaa
    14401 gcacccgtag ttacgcctgc ggtcaagcac agttgcctta tcttagtttg ctgaaatcct
    14461 actttttcaa aatggcttag tccactttct attaattttt ggtgagttgt aatataatct
    14521 ctggtttcta tgggtacttc ctcctaataa gatgaattaa ctatattatc ttacacagga
    14581 cttgaagttt caatcgttaa cgtctattac tgaactcatt ccttagagct aaactaatga
    14641 gaaagagcaa aataactgat acaaaaagca atcctacaag aattaataga ctcatctaaa
    14701 tcattcacct tttctaaaat aatccgagaa agatttaaaa aaattatatc cagctattag
    14761 gataagtcct atcataatca ctccaatagc cattttctta tcctccctaa aaataaagcc
    14821 ttttacttaa aacctttttt gtaatcgtca ataaattttt tccctttatc agttaattga
    14881 aatcctatat ctaaatagtc ctcatatcta agtttagtca gcatctcact tacagatgct
    14941 ggactaacac ttagaacttt tgctaaatca ttatttttta atttcttttt tctttttgat
    15001 aattcctgaa ttgctagtaa ataaattagt atagtagttg ttttaatttg taccatacct
    15061 accctccaaa ttatttcgaa aggccttcag caattttatc caggttccat ttcatcatcg
    15121 catagtaact atcaccatct tgtccttttt ctgcaattga atcagtaaaa atcgttgaat
    15181 agataggaat attggtatct tttgatactg ttttcattgg tctatcgtcc acactgcttt
    15241 ctacgaataa ggagggaact tttgttgtgc gtaatttttc aactaagtgt tttatttgat
    15301 ctggtgttcc ttcttcttca gtgttgattt cccaaatgta agcagaaggc acattatacg
    15361 ctttcgagaa atatttaaag catccttcac ttgtaacaat cattttttta tcattcggaa
    15421 ttgaagcaaa tttagattta gcttctttgt ctagagaatc caatttttca atatacttat
    15481 ctagattttc tttatagaat tttttattat caggatcttt ttccgctaac tgtttttcaa
    15541 tatttttagc gtaaataata ccgttttcta aatttaacca agcatgggga tcttccttcc
    15601 ctttctcact ctgaccctct aagtaaataa catctatgcc atcacttgct gcaaaatagt
    15661 ctttgttttc ctctttgttc gcatttttta ctaattttgt aaaccaagca tttcctccag
    15721 tttccaagtt aacaccgtta taaaaaatca aatctgcttt tgaagttttt tgaacatctt
    15781 caggcaaagg ttcatattcg tggggatctt tcccaatagg tacgatactg tgtaaatcaa
    15841 ttttatcttt tgctatattt tcagtaatat ctgctaaaat cgaattagta actactacct
    15901 ttaatttttc gttcgaagcc actgtatctt tgtctttact atttgttgaa catgccccga
    15961 atataaaaag agcaatcaaa atccccagac ttcccagtac tgctttccat tttctcatca
    16021 taactttctc tccttctttc ttaaaaattt ttgttttggt gagattagaa aactaattac
    16081 aaataagaat gccgctgtta aaacaatact tgatcctgct gctatgttaa aactataacc
    16141 aatgaacaaa cctagcaatg atgagcacgc tccgactgtc gccgaaataa atatcatagt
    16201 ttttaaactg tttgcatata aatatgctgt agcagctggt gtaattaaca ttgcaacaat
    16261 taatatagtt cccacacttt gcatagctgt tactgctact aaagttaata gaatcattaa
    16321 tagataatga taaaaactga cattcatccc cattgctttt gccattaatg gatcaaaaga
    16381 agtgattaat aattctttaa aaaatagaac aactgtaacc aacactaaaa cagaaacgcc
    16441 aattgtaatc cacttatcaa tatcttgtac agctaaaata tttccaaata agatatgaaa
    16501 taaatccgtt gagctatttg caactcctat aaggataact cctaatgcta aaaaagaact
    16561 gaaagtaata ccaattgctg tatctccttt tattacacta ttgcttttta taaaagtaat
    16621 aatgatagaa gctaatagac caaatacaat cgcaccaata aaaaaattaa tacctaaaat
    16681 ataagaaatt gctactcctg gcaaaacagc atgagaaata gcatcaccca taagagacat
    16741 tcctcttaaa ataataaaac aacctactgt tccagaaaca atccctataa ctacagatgt
    16801 aattagagca ttctgtaaaa agtgaaagtc atacagacca ttaataaaat tttgaagcat
    16861 attat
//
LOCUS       DAXQKX010000053        16655 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.054, whole genome shotgun sequence.
ACCESSION   DAXQKX010000053 DAXQKX010000000
VERSION     DAXQKX010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16655
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.054"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..565
                     /gene="scm"
                     /locus_tag="ACF3MF_002052"
     CDS             <1..565
                     /gene="scm"
                     /locus_tag="ACF3MF_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HFE3928014.1"
                     /translation="STDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTSASSDSTDTST
                     TTSDSTDTSASSDSTDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSSTTSDSSDSST
                     SSDSTDTSSTTSDTRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKRALPKTGSQSN
                     NWITLAGVILLVIGLRITFMSYKKSKR"
     gene            complement(720..1706)
                     /locus_tag="ACF3MF_002053"
     CDS             complement(720..1706)
                     /locus_tag="ACF3MF_002053"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFE3928015.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(1729..2295)
                     /locus_tag="ACF3MF_002054"
     CDS             complement(1729..2295)
                     /locus_tag="ACF3MF_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HFE3928016.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(2309..2725)
                     /locus_tag="ACF3MF_002055"
     CDS             complement(2309..2725)
                     /locus_tag="ACF3MF_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HFE3928017.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(3182..5116)
                     /locus_tag="ACF3MF_002056"
     CDS             complement(3182..5116)
                     /locus_tag="ACF3MF_002056"
                     /EC_number="1.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFE3928018.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5418..6353
                     /gene="pplA"
                     /locus_tag="ACF3MF_002057"
     CDS             5418..6353
                     /gene="pplA"
                     /locus_tag="ACF3MF_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular electron transfer flavoprotein
                     PplA"
                     /protein_id="HFE3928019.1"
                     /translation="MKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSESSTAQSST
                     AKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKYDNVNENG
                     ESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSSESFQNYA
                     QQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGKVTESNFD
                     YIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPANVEVVTGA
                     THSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            6443..7546
                     /locus_tag="ACF3MF_002058"
     CDS             6443..7546
                     /locus_tag="ACF3MF_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HFE3928020.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            7559..8512
                     /gene="menA"
                     /locus_tag="ACF3MF_002059"
     CDS             7559..8512
                     /gene="menA"
                     /locus_tag="ACF3MF_002059"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HFE3928021.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFDLVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(9447..10793)
                     /gene="gor"
                     /locus_tag="ACF3MF_002060"
     CDS             complement(9447..10793)
                     /gene="gor"
                     /locus_tag="ACF3MF_002060"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HFE3928022.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(10927..12180)
                     /locus_tag="ACF3MF_002061"
     CDS             complement(10927..12180)
                     /locus_tag="ACF3MF_002061"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HFE3928023.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(12186..13109)
                     /locus_tag="ACF3MF_002062"
     CDS             complement(12186..13109)
                     /locus_tag="ACF3MF_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HFE3928024.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(13330..15822)
                     /locus_tag="ACF3MF_002063"
     CDS             complement(13330..15822)
                     /locus_tag="ACF3MF_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HFE3928025.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(15829..16296)
                     /locus_tag="ACF3MF_002064"
     CDS             complement(15829..16296)
                     /locus_tag="ACF3MF_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HFE3928026.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(16432..16505)
                     /locus_tag="ACF3MF_002065"
     tRNA            complement(16432..16505)
                     /locus_tag="ACF3MF_002065"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16469..16471),aa:Arg,seq:acg)
     gene            complement(16563..16636)
                     /locus_tag="ACF3MF_002066"
     tRNA            complement(16563..16636)
                     /locus_tag="ACF3MF_002066"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16600..16602),aa:Pro,seq:tgg)
BASE COUNT         4921 a         3487 c         2965 g         5282 t
ORIGIN      
        1 cagtacagat actacctcta ccacaagtga tagcacggac acatcagctt caagtgacag
       61 tacagatact acctctacca caagtgatag cacggacacg tcagcttcaa gcgacagtac
      121 ggatacatct accacaacaa gtgatagcac ggacacgtca gcttcaagtg acagtacaga
      181 tactacctct accacaagtg atagctcaga ttcatctacc actacaagtg atagcacgga
      241 cacgtcagct tcaagtgaca gtacagatac atcctctacc acaagtgata gctcagattc
      301 atcaacttca agcgatagta cagacacgtc gtctaccaca agcgatacac gtcatgcaag
      361 tgtctccttc tcaaaaacaa gttcggataa caggacgaac tttaacttaa ctaataaaac
      421 aagcaatgac aatggaaaca aatcaaaaag agcacttcct aaaactggaa gtcaatcgaa
      481 taattggata acactcgcag gcgttatatt acttgtaatc ggtttaagaa tcacttttat
      541 gagttataag aaatcgaaaa ggtaaaaaaa tattcaagat aaaaaagagc aacgtcgcta
      601 acggacgttg ctctttattt ttgcttttta tcataaatac aagaactaca attcaatttg
      661 tcaaaaaaca cgtagatttc cttctgagaa atttatttac gtatcgaacc tttccctatt
      721 cagtctttgc gatccaaaat cagttgggta agggaaaaga gattctcttt tgttcgaaga
      781 gaggtggcag gtaatttctt tatttccttc aaagcctttt ctgtgtaaga ggccgctaac
      841 ttcctagctt cttccacgcc tcctgtatgt tcaacgattt tgcgtacggc gtcgacatct
      901 tcttctgtca ttgccgcttt cttctctaaa taaggtagta gctttggttt gtttttttgc
      961 aaagagtaga tcaacggtaa agaatagacc ccttgacgca tgtcttctag tacaggtttg
     1021 ccgatttcct ggctctcttt tgtataatct aaaatatcat cgataatctg aaaggccatc
     1081 ccgatagaaa gtccgatatc tcctgctttt tttgcgaagc gctcgcttgt tccactttca
     1141 aaagcgccaa cagaacaact taattggaac agttcagctg tcttacctga aatattttcc
     1201 aaatattctt ttacagaaag ttcataatta tagcgatcat ccatctgccc taattcgcca
     1261 ttcaatactt tttccatact gcgagaattc aattggagac ttttcaagga agtggagtaa
     1321 tcagacaata gtttaaaaca gcagacaaat aaatagtctc ctgcatagac agaaacgaca
     1381 ttaccaaact gactacggat attaggctga ccacgtcgca gatccgcttc atcaacgata
     1441 tcatcatgga tcagtgtggc cgtatggagc atttcgatag aagctgccaa agcgatggct
     1501 ttgtctcgat cttgctctgg tccaaattgt gagaacaata gctgataggc aggacgcaac
     1561 agctttccgc cggcatggat cgtttctttg atggcttgtt cgacaggttt gtttttcagg
     1621 cggacagttt cttccatccg ttttagtgtt tctgtcaatt ctttacttaa agcaggatag
     1681 ttttcccaca ttggatgtag cttcataaaa aaactccttg tgtgacgatt attttttggt
     1741 aaacattggg ctccattttt gtttggttcc ctgctcataa tctttttgga atcgttgaag
     1801 tgtctgcaca tgtcgtaaaa gataattcgc tgcgatcccg attgcaatcc ctgataaaat
     1861 ccctaaaact gaaaggactg gcaagtacaa catgactgtc catgattgtg caatgaaaga
     1921 agccatcaaa agctgtccga cattatgcat gaaaccgccg gccgcactaa ttccgatgat
     1981 actgacacgt tttggtccta attgcttgac caataacatt ccaaaataac taagcaaagc
     2041 accactcata ctataaagga atgtggaaat cgttccgcct agcaaagtag tcaggaatag
     2101 tcgtagccaa agtagtaaga agctgtcttg ttttttcatg gtaaaaatgg caacgatcgt
     2161 gattagattg gctaagccta gttttgcacc aggcgcaaaa gaaaaaggat aagggatcat
     2221 attttccaat aaaccaatga tcactccttg tgcaacaagt agcgaaatat aaatcatttt
     2281 ttgtaattta ctcatggtgt gtgaaggtct aataaatcag actgtcttcg tcacctccat
     2341 ctgttgaacg gacttcgatc actaatttat gtggcaaaca gacgatggtt tcgccatttt
     2401 tcgttgccca gcctcgacgt acgcagatct ggtcatcgca atctgcttct tttatccgta
     2461 ctcgatcgcc atctatctcg atcaagttat aatctccgtg ttcatctttg taagtatatg
     2521 tgttgctctc ttctccagcc atcaaaggga atgttttgat ttctgtgcca tccacacgca
     2581 gtaccgcttc tttttctgct gttgcggtgt tttgctgaag accaaaaatc atgactggta
     2641 aaaaagaaag aacagtcaaa agcaaaataa taaaaacatc ccaaggtttg agcagacttt
     2701 tttcagcaaa ttctttaagg ctcatttttg ttctcctttt tccagattaa ctcacccaat
     2761 tttagcataa aaacaagagg ttgtgacacc tgtgtcttgc tttgagtaat aagaacgaag
     2821 aatagaaaac agctttccat gttttctaat tctttgggct tattaccgag aagcagcagg
     2881 tggaacaccg tttataacaa gaggttgtga cagaagtggg caacttcaag aaataagaag
     2941 gaatttacga aaattacttt tcaagttttt gtgaaatttc ggcttatttt tcgaagaagc
     3001 tacttctgga acaccgttta taacaagagg ttgtaacaga ggttgtgaca cctgtgtctt
     3061 gctcatggag gcttatctcg ggcatcttat tcctttaatt ttacataaaa aggaggctgt
     3121 gacggtttgt ctcagcccct ttctattgaa atcttgcatt caaataacgt tctttatcta
     3181 tttatttctt gccgtactgg gaacttggtc taccgtacca ccaattacct agtgtacgtt
     3241 gtagccatgg aattacccag cgatccaacc caatcgcacg tccggaaccg ttcatcaatg
     3301 cgaaagcaac aaaaatgaac caaatgttta cccagtaaaa catgcctgat aagcagaacg
     3361 tgatcaccaa tacaatcgtt gtcgcactgc atagccatgt gaataatcca gcaatcaatg
     3421 ctaatgccaa ggcaatttca aagaatacca tgaatttttg gaagaacatt gctacatcat
     3481 tgtttggcat gatcacttgc atgatctttg tgaaccagtc tggtgacttc tcaatcacag
     3541 ccattggttc ttcaccgtat gcataactca aaccaaaatg tgcagcttga gtcgctgctt
     3601 ctccggcact tgcccctgct ccgctggcag ctgtggttgc atcaccagca gcagaagcac
     3661 cactggcaac atctgttaca ttgtattccc atgtccaagg gaacacactg tttccagtga
     3721 accatgatcc ttcaccaaac caagtacttg gtttgaacac ttcaccattc ccaatgattt
     3781 ttttggaagc ttcaacgaac caaactaaac catagaaaat acgaagtggc acactccata
     3841 agacattgcc gtaacgagaa gaatgtcctc gagtcacgtt gcgatcatct ttgatatgga
     3901 aaaactcatg cattaaatat tggaacatat aataaccaga acgaatatca aagaagtatt
     3961 tcaaattcac gatatgtttc attacgatag ctaaaaatcc gcttaaatgg atcttatcaa
     4021 ataggttagc taccccccat ttggcaccaa tagaaaccat aaatccttga tagtttcctt
     4081 taaatttatg cttttctccg cctttgatcg aagccacgat attcgctgcg gctgtgtgtc
     4141 ctgtttgttc agcagcttga acgatctgcg gtgtcggtgt tcctgggaat tcttcataaa
     4201 agactaaatc accaatgata tagatgtttt tatcttcgta gccttttgcc tgcatatatt
     4261 cattggcgat caaccgctgt ccgcgtgctg attctaatcc aaagtcagca gcgtcagaag
     4321 ttcctttgac accagctgtc caaatcagtg tgtgagtcgg aatgttgcgt ccgtctttca
     4381 atttgatatg atcagcagcc acttctacga ttggtgcatt caataataat tccacgttgt
     4441 gcttacgcaa atagcgttca gcttttgcag catcatttcg atccaacata ttcaagatcg
     4501 tcggcattgc ctctacgacc atcagtgtga tttcgtttgg atctaattta taatctttgg
     4561 ctaggcgatt tttccagtcg atcagttccc caatcatttc aataccggta aatccagaac
     4621 cacagacaac gaaagtcagc atggctttac gcagttcatc atctggttcc aatgcagctt
     4681 ttgctactgt cttctcaata tgttcccgaa tccttacaga atcttcaaat gaccaaaggg
     4741 tgaatccgtg tgctttgaca ccaggtgtac caaagtcatt cggctctccg cccattccaa
     4801 ggatcagctg atcaaaagga taggaaccta atttggtctt gacgattttt cgttctttat
     4861 cgataccgat tacagtgtct gtgacaagtt gtacattctt ttgacgagca aacaaatgct
     4921 gcagatcgta ttggattgct tctggttcta cacgtccgcc agctacttca tgcaactcgg
     4981 tcatcatagt atggtacgaa tgacgatcga tcagagtaat tgctacatct tcttttttca
     5041 gtttctttgc caagtatttt gtagctgaaa caccggcata tcctgctcct acaacgacaa
     5101 tattttgctt tgccattgat catccgctcc ttatagacta tctatataat gaatatatga
     5161 taattctttt agtttgatac ttattacaca atctccatat attatataga tgttctgttc
     5221 ttttgtctaa ctccttttgg atttttttca aattttaaaa taaagcgttt tttcacgaaa
     5281 tttgctgaaa gaaaacgttt gaaatattac atgggttatt tatcaaaaat agttgactta
     5341 taggctaaaa agattagaat gtataatgaa tcacaaagaa aaattgtgga ctagaaatgg
     5401 aatggtgggg tattaaaatg aagaaaaaac gttttgtaac tggatttgcc gtattagcat
     5461 tttcagctct agtgttaggc gcttgcggcg cagatgacaa cggaagctca aactcttctt
     5521 ctgaatcatc tacagcacaa tcttcgactg caaaaagcac aacagaatca tctgcaaaag
     5581 ttgtagctgg cggagatttg caagacggca catataaatt agaagaaaaa aattattcaa
     5641 atggttaccg tgcagtcttt gaaatggttg taaaagacgg caaaatcact gaatcaaaat
     5701 atgataacgt caatgaaaac ggcgaatcaa aaacaaaaga tgcagaatac aacaaaaaca
     5761 tggaagcaaa atctggcaca aacccagaaa aatacattcc tgagttgaat gaccaattct
     5821 taaaagcaca aagcgcaagc ggtgtggaag tcgtaactgg agctactcac tcatctgaaa
     5881 gcttccaaaa ctacgcacaa caattgatcc aagctgctca agctggtaac acagatacaa
     5941 tcgaaatcga caatggtgct gatttgaaag acggcactta caagcttgaa gaaaagaact
     6001 actctaacgg ctaccgtgtg caattcgaaa tgacagttgc tggcggcaaa gtaactgaat
     6061 caaactttga ttatatcgac aaagacggta aatcaaaaca agatgataca gaatataatg
     6121 aaaatatgaa agcaaaaagc ggtacagaac caaaaactta catccctact ctgaacgacg
     6181 aattcgtcaa agcaatgggc gaagaagatg gctcacctgc taatgtagaa gttgttacag
     6241 gtgctacaca cagctcacat tcattcatca tgtacgcaca acaattagtg aatgcagctg
     6301 aaaaaggcga cactcaaaca atcgaagtag ataatatcgt aacagaaaaa taatcacata
     6361 atcatactaa taaaagttgg agggtgggac gatagccaga ttaggcagtc gtctcacctt
     6421 tcaaaatgaa gagaggaaaa agatgcggaa aaaactacta ttttccttaa tcacactggg
     6481 catctctttt atggtgctaa ctggctgcag caactcagca aataaaacaa ccactgaaag
     6541 ttcagcagct accaagatat tgaaagatcc atattctgat gaacagttct tgttagggac
     6601 ttacgttcgt atccgtgtgt atgatgaagg caaagaatca gcattgaaac ctgccttcga
     6661 tcgagtaaaa gaacttggtg ataaaatcac gatcaatcaa aaaggttctg agatcgatga
     6721 agtgaatgag caagctggga tcaaaccagt aaaagtttct gatgacgtct acacgttagt
     6781 caagcgggcc tacgaatata gccaagattc tcaaggcgga ttcgatatgg cgattggtgc
     6841 aatcacacaa ttatggcgaa tcggttttga tgacgccaga aaaccttccc aagaagaaat
     6901 cgatcaggca ttgaaattag tggattatca taagatcgaa ctaaatgaca aagaaaaaac
     6961 tgtttatcta aaagaaaaag gaatgatcat cgatttaggt gcaatcgcca aaggttacat
     7021 tacggacgaa gtagtgaaag tcttgaaaaa acaaggagtg accactgcca tcgttgactt
     7081 gggcggtaat gtctatgtct taggccacag cccaagaggc gaaaaccaag actggacagt
     7141 cggcatccaa gatccgaaca tggctcgcgg atctgtttta ggttctatta aagaacggaa
     7201 caaaacatta gttacctctg gaatttacga gcgttattta gaagtagatg gcaaaaaata
     7261 ccatcatttg tttgatccaa aaacgggtta tccgttcgac aatgatatcg caagtgtcac
     7321 gatcataaca gataaatcaa ttgatggtga cgggttgtct acagcagtct tttcaatggg
     7381 tgtgaaaaaa ggactggaat acgtcgaaag cgaattgaat aacgggacgg aagcgatctt
     7441 cgtgacaaaa gacgataaag tatatgtgac cgatccaatc aaagacacct tcaaattatc
     7501 ggaggactcc cattacacga tgggtgaccg ttctgaacta aaataaggag tacgaaccat
     7561 gacactaaaa atctttttag aagtagttga aatacgaaca aaggtggcta gtgtatttcc
     7621 ttttgcggta ggggtattat tctctatcgc tttttttcat gagatacatt ggctaaacac
     7681 ttttttattt tttattggaa tgctagtttt tgatttagcg actaccgcta tcaataatta
     7741 catggattat gaaaaggctc attctgaagt atataagtat gaagaaaatg tcattggccg
     7801 cagaaatcta tctcctgtat tgattcgaaa catgatttta gctatgattg catttgtttt
     7861 tgttatcggc gttattctaa cgatcaatac gggttggctt ttacttttga tgggatttat
     7921 ctgttgtttt attggagtat tctatacatt cggaccgatt cctttatctc gaatgccttt
     7981 aggggaaatt ttcagtgggg tgactatggg ccttggaatt tttgccatgg tcgtttatgt
     8041 caatacattc ggttcagatg tctatgatct gacagtcaac ttttcatctg gacaatttga
     8101 tttggtagga aatctttggg ctatagcagc aatcgtatta gcttccttac ccttggtgtt
     8161 tacgattgcc aatatcatgt tggctaataa tttgcgggat cttgaccgtg atattgaaaa
     8221 tcatcgctat acactagttt tttatatcgg acgtcctgcg ggaacagtct tattccagct
     8281 attgatgtat gcttgctatt tcgtgatttt aatggggttg ttgagcggta tctatgaatg
     8341 gccgatcttg gtcaccttct tgaccttgcc aattgtgaag aagcatttgg atcaattcaa
     8401 gcaaacgtta ccccagccta tcagtttcag ctattccatc aaaaatatgg tcttattcaa
     8461 tgccagttat gtattggggc tattactaac aatcattatg caagccattt aacagcatga
     8521 agaggttgtg aaaaaactgc cctgcatcaa gtaataagaa cagccaaata aaaatagctc
     8581 cttatatttt tcgtttggtt gggcttatta ccgcagatgc aagcttttga acaccgttta
     8641 tcaggaggtt gtgaaaaagt cgcttagttt cgagtattaa gaaaaatttt gtgaaaatgg
     8701 ctttccacat ttttgcataa atttggctta ataccgagaa actggctttt gaacaccgtt
     8761 tatcagaggt tgtgaaaaag tcgcttagtt tcgagtatta agaaaaattt tgtgaaaatg
     8821 gctttccaca tttttgcata aatttggctt aataccgaga aactggcttt tgaacaccgt
     8881 ttatcagagg ttgtaaaatc agtgttttgt cctgagtatt agagaaacaa atggaaaaat
     8941 agttcctcat attttgccgt tttttgagct aataccgaag gacagctgat tgaacactat
     9001 ttgttcggaa aaagtgacta actatgacac aatttttttc acagtccctt ttttcacttg
     9061 atttgattcg taccagcgaa cttgacgaga actttcttgg tttggtaact atatggtatt
     9121 cttttaacat cctcgtttgc ttcttctaat ttatttatac aaagtcacac ttttttaaac
     9181 atctgttctt cgatacattt ctatttcttt taaacatcga taccaatatt ttgaacttaa
     9241 gagtgcatac caaatggatt catttactct tcgtcagtta cgaagataat caaaatctcc
     9301 aacttcccta cttatttcgt tttgagaatt atcgaagcaa tcttacataa ataactaaaa
     9361 aacaaaaaac cagaaaatca gtatactgat tttctggttt tacatggttt gttcaataaa
     9421 aagctgttgg aactgttaat attaaattat cgcatcgtta cgaattcttc cgctcctgtt
     9481 ggatggatgg ctactgtatt gtcaaagtct tctttagttg cacccatctt gatagccacg
     9541 gcaaaacctt gcagcatctc atcgacacca acaccaatag catgtaagcc gacgattctt
     9601 tcttcttttc cgacacagat caatttcatt tcgcattttt ggcgataatc atttaatgca
     9661 aagtacattg gggtaaagcg tgaacgataa actttcaatt cattttcgcc atatttttcc
     9721 aatgcttctt cttctgtcaa accaattgtt gcaattggtg gatgcgtaaa gacgactgtc
     9781 ggaacaagtt tatagtcaag ataagaatct ttctttccat taaataaacg ttctgataaa
     9841 cgtctaccag ctgcgattgc aacaggagtc agatctaatt taccgatcac atcaccaaca
     9901 gcaaaaatat gttcatccgt tgtattttgg tatttatcta ctttgataaa cccttttttg
     9961 tccaattcca catttgtatt ttccagacct aatttttcgg tattcggtac acgtccaccg
    10021 gcaaaaagta cacaatcacc agttaaggtt tcaccatttt caaatagcac cgtatattcg
    10081 tcattgtttt tagtaatttc tttagcaata tgatgtgcgt aagtttttat tccagcttct
    10141 tggtacattt ggatcaaatt gtccgaaagc attttatcaa acgttctaag tggtcgttct
    10201 tttcgatatg cccacatgac ttcactacct aaaccacgaa atacacctga aagttcagcc
    10261 gcaatgtatc cagcacctaa aacgattgct ctcttaggta actctgttaa ttcaaaaaat
    10321 ccatttgaat caattgcgta ttctccacca ggaatggtca ttttacttgc acggcctcca
    10381 gtagcgatca agattttagg agcacgatag gtttcaccgt ttacttcgat cgtttgacta
    10441 tcgataaaag tagcgtaacc ttttatagcc tcgacatgat tgctatctaa tcctctttga
    10501 taagcaccgt gtagaaaatc aatatatttt tctcgtcttt ctactagacc ggcgaaatca
    10561 acatttttta aatctgcttg gataccgtaa cttgaggcat ctcgttcaat tgtttccaaa
    10621 atcgtacttg cttgccacat aactttttta ggtacacaac cgacgttgac acatgttccg
    10681 cccaattcat tcgcttcaat cagcaaaact tttgcgccat gcatccctgc tctgtttgct
    10741 gaagcaatac cgccagagcc gccaccaatt acgatgtaat catatatttg cattttgttc
    10801 ctccttattg aagagatcaa tcaaaacctt tatttaacga tcctttttct acagaaaaca
    10861 agtgtaacac ttttcttgaa ttttgtatgc gaagatgctt aaaacaggga tatatcagct
    10921 ttttccttat ttacgttttc ggatcatatc tccaggtttc accggctgtg cgactggcat
    10981 agttaaaatc atcattggat ttggtgctcg gtcaatggat tcgccttctt cattatgcat
    11041 aacttcaacg gtttgactga aatgactgaa tcctggacca taaaattcga tttcatctcc
    11101 tacagaaaac aagtttctct gacgtatcgt agcaatctgt gttgcctcat cataagataa
    11161 tacttcaccg acaaatttat atactgggat tttacgacgt tcaccgaata attgttcgtt
    11221 ttcagttggt gtattgtagt aaaaacctgt agctaattct cgttgtgcta ctttccataa
    11281 ctcgtcgatc cattcttgct tgcagacata gttttcagga tcttccatat aactgtctac
    11341 agccgcttta tagacatttg acaccgtaga tacataatgg atcgatttca ttcttccttc
    11401 gatcttgaag ctgtctacgc cgttttcaat caattctgga atatgttcga tcattgacat
    11461 atccactgca ctcatcgaga attcttcttc cacttcgcct gtatcagtta aactgtttcg
    11521 ttcttgacca aaaggcatat cgaacaatcc atacttccag cgacaagatt gagaacatcc
    11581 gccacggttt gcatcccgca tcgacatatg gttggacaat gtgcatcgac cagaataaga
    11641 gatacacatg gcaccatgga taaatgcttc gatttcggta tccgtatttt tacgaatctc
    11701 tgccacttcc tccattgaaa cttcacgagc taaaacgaca cgttccaacc cttcttcttt
    11761 ccagaattcc aatgtctcaa aattagttgc tgaagcttga gtggataaat ggatcggcag
    11821 acctggggct tctgtcgcac aaatttcgat caaagctgga tcagaaacaa tcactgcaga
    11881 aataccgaca tcacgcaaac tgcggaaaaa ttcccctgct ccatcttcat ttccttcatg
    11941 ggtgaccata ttagcagcaa cgtatacctt cgcatcatgt tcttttgcaa aagcaactcc
    12001 ttcagccatt tcttcataag taaaattacc tgcacggctt cttaaaccat atgcattccc
    12061 gccaatatat actgcatctg ctccataatg gatcgcggtt tttaactttt ccagtgttcc
    12121 tgctggcgct aggatttctg gtcgtttcaa ttttcttttt actgtcattt ctttcatcat
    12181 actccttatt tgatagcaga aggatcaata taaaagaatc ctgtatctaa ttcacggttt
    12241 tcaggatgca atttactgat ttcgctagtc attttttccg ctttttcttg atcccagcta
    12301 ccttctaaaa tttgtttttt tgcttcggcg aatagtcgag tgatgtttac gaatttttcg
    12361 cctggagtaa ataatccgtc caatttccat gtacagtaat gatgctgata aagttcattc
    12421 aattcattcg agagattcag atcattgctg gcaaaaatat gtgtgccatg actatcttca
    12481 taaatagaat aatgtgtctc ttctttttta ggttccgaga taaaaagacc tctttcacga
    12541 tctttttgtt cgtcttgttt cgtatagtta tagtaattct gtagcagtgg acgtttggat
    12601 tgatggatgc atgtagcacc atacacaagg gtttctacag gaatatcgag tttttcttcc
    12661 atcgccttca tctcttcaaa aggaacttca cgagcaagta ctgctccaac tgcgcctttt
    12721 ttcgcccaga aattgatttg acgtgcgctc gttactaatg tttcagcatc ataaatatac
    12781 ggtatacgca attcaggatt ttttttcatc gtataaataa tacctgtatc accaactgtg
    12841 atcacatcta cgtttatttc ttttaaaaaa gccaaatatt caggtacatt tttcattttt
    12901 tcaggatgaa tgatcccatt tacagcaata ttcgcttttt taccatactt gtgtgctaat
    12961 tctaccaatt gtcgctgttc ttctcgtgta aatgaagcag gcagacgcaa tccaaattgc
    13021 tcttcaccga aatatagtgt atctgcacct gcagcaagca actgttctgc ttgttcaata
    13081 gtttctactg tggttatgag ttcgatcata attttctcct cctacaactt cataatagta
    13141 gcatagctct aaaaactttc caatacttct tctatttaaa gtcggatttt tgaaaattat
    13201 ttcacaaaaa atcaaaataa agttcgatat attctgtcca aatataaaaa gagattgtga
    13261 caaaaatctt gtcacaacct cttaatcaag tcttactatt ataaaaattc agctacacag
    13321 gccaagtaac tatagggaac ctactgtttc ctttttaggt ccgcgaacat tcaatgtgat
    13381 cttacctttt gaagcaccta ctgttacgtg gtcacctaaa cgaatttctc cgccaagcaa
    13441 agcctcgctc aatcgatctt caatttcttt ttgaagtgcg cgacggattg gacgtgcacc
    13501 atattcagga tcaaatccag ctttcccgat cacatcgatt gcagatggtg tgattttcac
    13561 ttgaatatct tgttctttca atcgtttgat aatcgctttg ctcatgattt ggacgattgt
    13621 atggatttca tctttactca atgaatggaa gacgacagtc tcatcgattc gattcaagaa
    13681 ttcaggtcgg aaagctttct ttaactcttc taagatacgt ttttgcatgg ctttgtgatc
    13741 tttagtaaca tcttggacat tgaatccgac atttttttct tctcgaattt gtgtcgctcc
    13801 gatatttgaa gtcataatca tgattgtatt tctaaagtcc acttttctac ctttagaatc
    13861 tgttaaatga ccatcatcca atacttgcag aagtaaattg aaaacgtctg gatgtgcttt
    13921 ctccacttca tctaagagaa tcactgaata tggtttttga cgaatttttt ctgtcaactg
    13981 tccaccttca tcatacccta cgtatcctgg aggagacccg attaatcggc ttgtactgta
    14041 tttttccata aattctgaca tatcaacacg gatcagggca tcttcacttc caaacatgac
    14101 ttctgaaagt gctttggcca attctgtttt tccgacacca gttggtccaa ggaacatgaa
    14161 tgaaccaatt ggacgatcag gatctttcaa tccgcttcgt gcacggcgga tcgcacgtga
    14221 aactgctttg acagcctcat cttgaccaac gacacgttca tgcagaagtc cttccagttc
    14281 taacaagcgt tcgctttctt ttttctccaa ctgctgtaga gggacaccag tccactccga
    14341 tacaactgta gcaacatctt cttctgttac acgatcagaa taaccttgct cctgttttgc
    14401 ttcaattgca gaaacttttt gcagcttttt acgtagtgct ttttcttgtc tgcgtaattg
    14461 agcagcattt tcaaagtctt gtttttggat cgctgcttcc ttttcttgta ctagttcatc
    14521 gatttctagt ttgatcacag ttgattttgt taagtgatcg gtttgatcca aacggacttt
    14581 cgctgctgat tcatcgatca aatcaattgc tttatcgggt agttgacgag aagtgatata
    14641 acgaacagaa agattgactg ctgctcgtac agcttcatct gtgatctcca ctccatggtg
    14701 ctcttcatat cttgtacgta atccttgaag aatcacttct gcttcttcag gagttggctc
    14761 atctacttga atgcgagcaa aacgtcgctc taatgcagaa tctttttcga tatatttttg
    14821 atattcatct agggtcgttg ctccgatcgt ttgtaattct cctcgagcta acgccggttt
    14881 caagatattc gaagcatcaa ttgctccttc tgctccacct gcaccaatta aggtatgcaa
    14941 ttcatcaatg aataagatta cttgaccatc attatagatt tcgtcgatga cctttttcat
    15001 tcgatcttca aattcaccgc gatatttcgt accagcaacc aaagatccca tatcaagcat
    15061 catcaggcgc ttttcttgca tgtcttctgg cacttcacct aaaatgattt tttgagctaa
    15121 cccttcagca atggctgttt tgcctacacc aggttcaccc accagtacag ggttattctt
    15181 tgtccgtcgg ctaagaatct ggataagccg tttcacttct ctcgaacgac caacaactgg
    15241 gtccagcttg ttttcttttg ctaatttcgt caaatcacgt gctaatgaat ctagcgtagg
    15301 tgttccttgc ggtgtttgcc gtttatcttg tacatttaca tttctacgac gattcattcc
    15361 ttttccagca gaatcaccag ctagccccat tttttgtttc agaacttgac gggcttttga
    15421 aaggctgata cctaagttga tcatgattcg agtagccatg atactttcat cttttaataa
    15481 gctcatcaaa atatgttctg ttccaacttt ttgagaacca gttttcttca cttcgctgct
    15541 agctaaagca aaaacttgtt tcattcttgg tgaatatgga agaaagactc ctttagggta
    15601 agaacggata ccaccataac caatcagatg ttcaatttct tcataaattt ccgtttcatt
    15661 caaatccatt tcacgtaata cttttccagc aattccattt tgctcgacca ctaaggctag
    15721 taaaacatgt tctgaactaa ctgattgatg tttcaaccgt tttgcttctt cttgtgcaat
    15781 ttctaatact gcttgggctc tttcagtaaa aagttcttcc atctaatctc acttcccatc
    15841 ttcataactt aaacgttcca gaaatgctcg gagaatccga gcacgtgtat gatcttcata
    15901 ttcattgaaa ttcaatgtgt tttttgcaat tgcactcaac atcaagtttc cttctttttt
    15961 tgtaattatt tggtcttcat aaagtttttg aataatagca aaagcatttt tctcactgat
    16021 tgtatcatca aataactgat ttatctgctc aagtaattgt tttttatctg aaatccttac
    16081 ttttgcaatt cgtatataac caccaccacc acgtttgctt tctactagat aaccacgttg
    16141 gatggtaaaa cgggtattaa tcacatagtt gatttgtgaa ggaacacagt taaagaggtc
    16201 tgccatttca atccttcgaa tctcgatcat ttcactattt tccagaattt tctttatata
    16261 tgattcaatt aaatccgagg tattctgatg tgccatctta ttcattccct ttgactaata
    16321 ttgaccttaa ttataacgaa tttgataata gaaagaaaga agaacgcttt ttgttaaata
    16381 aatcctttag aatcaacaaa aaaaaatacg gaatatacta ttccgtatcg acgcgcccaa
    16441 gaggagtcga acccctaacc ttttgatccg tagtcaaaca ctctatccag ttgagctatg
    16501 ggcgcatatt caatttaaaa aaattataaa tcatttgaaa acaaaaagca agataaaaaa
    16561 aatcgggaag acaggattcg aacctgcgac cccttggtcc caaaccaagt gctctaccaa
    16621 gctgagctac ttcccgttta aaaaataaaa aagac
//
LOCUS       DAXQKX010000054        16510 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.055, whole genome shotgun sequence.
ACCESSION   DAXQKX010000054 DAXQKX010000000
VERSION     DAXQKX010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16510
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.055"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(46..243)
                     /locus_tag="ACF3MF_002067"
     CDS             complement(46..243)
                     /locus_tag="ACF3MF_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HFE3928027.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(637..2364)
                     /locus_tag="ACF3MF_002068"
     CDS             complement(637..2364)
                     /locus_tag="ACF3MF_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HFE3928028.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2357..3550)
                     /locus_tag="ACF3MF_002069"
     CDS             complement(2357..3550)
                     /locus_tag="ACF3MF_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HFE3928029.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(3737..4381)
                     /locus_tag="ACF3MF_002070"
     CDS             complement(3737..4381)
                     /locus_tag="ACF3MF_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFE3928030.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4475..4609)
                     /locus_tag="ACF3MF_002071"
     CDS             complement(4475..4609)
                     /locus_tag="ACF3MF_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HFE3928031.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(4611..6743)
                     /gene="feoB"
                     /locus_tag="ACF3MF_002072"
     CDS             complement(4611..6743)
                     /gene="feoB"
                     /locus_tag="ACF3MF_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HFE3928032.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(6740..7213)
                     /locus_tag="ACF3MF_002073"
     CDS             complement(6740..7213)
                     /locus_tag="ACF3MF_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HFE3928033.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            7614..7838
                     /gene="nrdH"
                     /locus_tag="ACF3MF_002074"
     CDS             7614..7838
                     /gene="nrdH"
                     /locus_tag="ACF3MF_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HFE3928034.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            7997..10156
                     /gene="nrdE"
                     /locus_tag="ACF3MF_002075"
     CDS             7997..10156
                     /gene="nrdE"
                     /locus_tag="ACF3MF_002075"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HFE3928035.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10206..11171
                     /gene="nrdF"
                     /locus_tag="ACF3MF_002076"
     CDS             10206..11171
                     /gene="nrdF"
                     /locus_tag="ACF3MF_002076"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HFE3928036.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11260..12399)
                     /locus_tag="ACF3MF_002077"
     CDS             complement(11260..12399)
                     /locus_tag="ACF3MF_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFE3928037.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(12708..13421)
                     /locus_tag="ACF3MF_002078"
     CDS             complement(12708..13421)
                     /locus_tag="ACF3MF_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HFE3928038.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(13675..14376)
                     /gene="nagB"
                     /locus_tag="ACF3MF_002079"
     CDS             complement(13675..14376)
                     /gene="nagB"
                     /locus_tag="ACF3MF_002079"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HFE3928039.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            14610..16142
                     /locus_tag="ACF3MF_002080"
     CDS             14610..16142
                     /locus_tag="ACF3MF_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFE3928040.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16333..>16510)
                     /locus_tag="ACF3MF_002081"
     CDS             complement(16333..>16510)
                     /locus_tag="ACF3MF_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFE3928041.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5119 a         3411 c         2863 g         5117 t
ORIGIN      
        1 tcattatata attcatgaac aatttgctta gcattttttt tcattttagc acttccctgg
       61 aattgctcca cctaaaaaac cacctataga cattcctgca atacaagtag ttgccttggc
      121 ccaatcgacc gtacatttat ttttagtgca atacactcca tttccataat attttccact
      181 atgagtggta cccccataga taagttgtgt ctctttaata gacaaaattt ttaaatgttt
      241 cataatctaa tcacccctaa attaatgttt ttagactatt attctaacat tcattaaatt
      301 tcaaaaaaca attccttctt gaaacgtagc aaaataattc ctgaataaga atttaatcac
      361 ttttaagtat ataaactatg tatattcttt aatatttttt gagaatgcac ttcgtacata
      421 ataaacttta atcacattag tctttcatac ctacgatcga tctctttgac tcgcacccat
      481 aaattcataa tagtttgtcg gcgtctttga acgtttcgaa gatgagctac gcattctctt
      541 tttttataga caaaaaagat agagacgaac atggagcttc caaatttgga tatttgatcc
      601 aattttggaa gctccattta tttcgtgtct gtctttttat tttttccagc tttcgactaa
      661 ttcttggttc tctttgatcc agtcttttgc tgcttgctgt ggatcttttc cattgttgat
      721 ttccaacata actttttcca tatctttttc tgaccaatgg aaattgtcta atactttgta
      781 agcttctggc tggtcttctt tcaatccttt tcgaaccatc gtatggatct gctcttcgct
      841 tcccattccg ttttcaggat cttctaagta tttcagatca tatttggcaa acatccaatg
      901 aggtgtccat cctgtaacta caattggttc gtgttttttg atcgcttgac ctagtgcaac
      961 ggtcattgct cctgaagaag atgtctctac tttccagtct ttcaagttgt catatttttg
     1021 gatcgtgttt tcagcagccg taactacacc agctcctggc tcgattccta tgattttctt
     1081 acctgcctga tcggttaact catcgatcga atttacatcc atgtaggctg gcactgctaa
     1141 accaactttt gctcctgtca aattggcacc taggtcttcg acttgatctt tatattgtgc
     1201 atattgtgaa ccatgagttt taggtagcca agctgaaacc atggcatctg actcgccatt
     1261 tgaaacagat ttccacatga ttgaattatc taatggcgtc atcgttacat catagcccat
     1321 ttgtttcaat acttcaccga ctacatttgt tgaagcaact tctgtatccc attcaacata
     1381 agataagttg atacgttttg tttctttggc agatgaaaaa ctccctatac caatcgcacc
     1441 taagatcact actactacag caccaatgat cagtccttga cgttttttac ttttctgtgt
     1501 tgttgctcct gcagcttttt tattgtttgg ctggttcaaa tgctgtgtaa aacggtcaat
     1561 gatgattgct aagataacta atgcaacccc gttgacaaat ccattcccga cttgtgctct
     1621 ttgcaatgct gataatacgc cgcgtcctaa gccgggtgca ccgatcatag aggcaataac
     1681 gaccattgaa agtgacagca ttgttgtttg attgatccct gccatgatcg tacttttagc
     1741 taaaggcaat tctagtttga atagtttttg acgacttgtg ctcccgaatg aatcagaagc
     1801 ttctactaat tctttaggaa cttgtcgaat ccctaaattc gtaaaacgaa cggttggtgg
     1861 cagagcaaag atgactgagg caaatacccc tggaaccatc ccgataccga aaaatgcaac
     1921 tgctggaatc aaataaacga atcctggcat tgtctgcata aagtcaagga tcggtttgat
     1981 aatactttgg gctttactgc tttttgccat caagatccct aatggtaccc caatgatgat
     2041 cgagatcaca ctagataaaa gaacaagtgt gacagtattc atcaaatcat tccatagacc
     2101 ttggttataa ataaaccata gaccgattaa tgtgaacaac gtaagtcctg gacgtttctt
     2161 agaaataaag aaagctgcta ccgtcaataa caagataaac aaaggagctg gaatcactaa
     2221 cagtaaattt gtaattcccg acatcactgc ctgtccaatc gtttgtaaaa atgaaaatag
     2281 gccagaaaaa gttgtcgtaa accattctgt gatattttct acccagtttg ccactggtaa
     2341 ttgatagttc aatagattat tcatgttcac tcacctcgct tgtttctgct aatgcttcaa
     2401 tcacactacc tcggatgacg acacctttta attttccatc ctctacaact gcaagtggag
     2461 tcggtgagtc ataaataata ttgaaaatat cacttaccac catgtctttc ccaatcaccg
     2521 tcacattttc atctaggaag tcgatcaatg gacgtttttg cttcctagct tctaacgctt
     2581 gatctgcagt gatgatccct ttcaggtgtc tctttctgtc aacagccatc agcatgctga
     2641 cttcttcatt acgcatcctt gtcaatgcaa cgtttggtcc atcagattcg atattcgtcg
     2701 tcaatgcagg taccatgatg ttttgagccg taagcacttt ggaacgatcg acttcttcca
     2761 caaattcacg tacataatca tttgctggat tggtcaatat ttcttcacct gttccgatct
     2821 gcatgatttc gccgtctttc atcaaggcga ttctgtcccc aatccgtaaa gcttcattca
     2881 aatcatgggt aatgaaaata atcgtttttt gaacattggc ttgcaggtcc agtaattcgt
     2941 cttgcatttc tcgccggatc agcggatcaa gagccgagaa cgcttcgtcc atcagcaaga
     3001 tctcaggatc atttgctaaa gctctggcta ggccaacccg ttgttgcatc ccaccagata
     3061 actgactagg atattggtct ttaaatgaaa gcaaactaga attttctaat gctttttctg
     3121 ctttttcttg tcgttcttct ttaggtacac cacggacttc taacccgtat tctgtatttt
     3181 ccaagatcgt tcgatgtgga aacagaccga agttttggaa aaccatattg attttatgac
     3241 gacggacttc tcgcaattct tctttgctta acttcgatac atcttctcca tcaatataga
     3301 tactgcccga agttggctca atcagacgat tcaatagacg gatcaatgtg gatttcccac
     3361 tcccggaaag ccccatgatc acgaagattt ctccttcttt tacgtcaaaa ttcacgtcat
     3421 acacaccaac cgttgcaccg gttttcttta aaatctccgt tttcggctgg tgatcattca
     3481 tcatatctaa agcggcttgt gtctttttac caaatatctt tgttaaatgt tttacttcta
     3541 cttttaccaa acaaattctc cttttttatg taaattcatt tttctttctg aaaaaagtga
     3601 ccacactatg ttaacatcat gtagtcactt tgtcaaaaat gaaagaaatt tgcttgtcca
     3661 aactgaaaaa aacttggcta aatctttgta aataaaaggt ttagccaagt taatattttt
     3721 ttaatatttc acacaatcat tctgcaagct gatgctccgg gtaaaaaaag tttgtcatac
     3781 gctgtagtgt atattcattt ccaataaaat gaacgatgtc ccctgccgta aatttagcat
     3841 aggggccagg tgaaacaagc agttcttcat tatgagaaat tgcgataact gtggcgccag
     3901 tcgcctgcca gatattcaac tcgctaattg aacggtccag atgcattgct ttttctgata
     3961 aagataattc aaacggaagt aaaggattca tcttatgtat tcgcttcgtt tgattgacca
     4021 gctgatccaa taattgagaa aaatgattca gctcatcttg ttgcttctcc acacttgcca
     4081 tgatttctgc ttttgtatct tggatggatt gtacatcttg atattgcaat aggaaatctt
     4141 ttgctttttc cttcgaagca acaaatgccc cacttccatg ccgtacttcc atgattccaa
     4201 gatctaccag cacattgata gccttgcggg tagtctcagg agaagcattg tacgtactgg
     4261 caagtgttga gcgggcatgg atcttctcac ccactttata tcggttttca acgatacgtt
     4321 cggctaaatc aacagcaatc tgctggtagc gcgggcggac gatttttttc tttccagaca
     4381 ttttctttcc tctttctttt tttactttcc ctcatcttac tatgctctag caaaataagc
     4441 aaaaaagggg agaatagcct cttgcaacga ctgatcatcg cttgatctgt tcctttttta
     4501 ctgggcaagc tgtttgacag tcatcacaat tcttaccgga ttttaaacga gtatagacaa
     4561 ttgcgcctgc acttccaaag attaacacac ttaataagaa tgtcgccatc ctattcctct
     4621 ccttctaatg acaatatagt ataaaactgg ttcttggatt ttggctgacg gaacaaaaca
     4681 taaacgagtc ctatcatcag taaaatagca agatacgtcc ctaacgctac ctgtccaccc
     4741 tccaataagt gtcccaactg ataaatcaca aaactaacta aataagctaa accgcattga
     4801 tagcctatgg cgatccaagt ccatttcttg gcattcattt cccgatggat agccccaatt
     4861 gccgcaaaac aaggcgcaca aagtaaattg aaggctaaca atgaataagc tgctgcggga
     4921 gtatatgtgt gttgtagcac ttgccagatt tctctgccat tttcggatac ttccgcatga
     4981 ccaaacaaaa taccaaatgt gccaataata ttttctttag cgaccaatcc tgtaatcgct
     5041 gcgactgttc cttgccagtt tccccaacca agcggctgaa aaacaactgc caggattcgc
     5101 ccgaaaaagg ctaagatact ttggtcttca gaaacaggtt gagcataaaa attataagaa
     5161 gagctgaacc agatcacgat actagaaaca aagataatcg ttcctgcttt tttaacaaaa
     5221 gacttgctgc ggtcataggt ttgtcttagg accgctgacc attgaggaaa atgatatgcg
     5281 ggcaattcca tgataaaagg agctgtatct ccagcaaaca aacgtgtttt tttcaagctg
     5341 attccagaga aaataattgc agtcatacca agaaaatagg cagaaggagc tacccaagat
     5401 tgatgaggaa aaaaggcccc tgctactaag gcaataatcg gcaactttgc agaacaaggc
     5461 atgaaggttg tgaccatgat cgtcaaacga cgatcttgct cgttttcaat cgtgcgactg
     5521 gccatgacgc ctggcactcc acatcctgta gcaatcagca taggaatgaa ggattttcct
     5581 gaaagaccga atttcctgaa aagtcgatcc atgacaaaag cgatcctcgc catatatccg
     5641 cagtcttcca gaaagctcaa gcataaaaac aatataatca attgcggtag aaatcctaac
     5701 actgctccca cgcctgcgat gatgccgttc aagatcagct cctgcatcca tcccgctact
     5761 tgccattcag ctaacaatct gccaacatgt tctggtaacc atgtaccaaa caatgtgtca
     5821 ttgatccaat ctgtccccat tgttcctact gtttgaatag ccagataata gatcagccac
     5881 atcacaaatg cgaagatcgg caaggctaac caacgattcg ttgcaatctg atcgattttg
     5941 tcactcatcg ataattggaa agaatcattt gacacaacac agagtgtaca tagttgggta
     6001 ataaattcat aacgttcatt gaccagaatc gtctcactat cgtcgtccaa tagtttctct
     6061 gttaactgga tcagttgctc gatctctttt tgctgagaaa ctgctatctc gtaatcctct
     6121 cttaccttct gatctcgttc aaaatatttc attgcatacc agcgtttctt gccgctttgt
     6181 tctcctagta catcttcaat ttcatgtaaa gctgcttcta aacgtggatc atatgtacag
     6241 ggaacaggaa tagaaggccg cttttttgca gactcctgaa tcttttcgat tagtttttcg
     6301 attccttgct ttttcaatac gctgattggt aaaactggta caccaagacc ataggaaagc
     6361 ttttctagat tgattttttt tccttctttt ttgatgacat ccatcatatt cagaccaatg
     6421 atcataggaa tgtctaaatc caataactgc gtagttaaat aaagatttcg ttctaaattg
     6481 gtagcatcaa taatgttgat gatcagttca ggctgttcct gaaccaaata atctcttgca
     6541 atcacttctt ctggtgtata aggagacaaa gaatagatgc cgggtaggtc ctgaatatga
     6601 atgttcggat tttttttcaa cgatccttct tttttttcta ctgttacgcc cggccaattc
     6661 cctacatatt gattcgaacc agtcaagaga ttgaacaagc tagttttccc gctgtttgga
     6721 tttccgacta acgcgatatt cattcttttt cctccctttg tatcaagatt agttcggcct
     6781 ctgactttcg taacgtcagt tcataccctc gcactgtcag ttcgattgga tctcccagag
     6841 gggctagttt tcggataact atttttacat ttcgcgtcaa tcccatatcc attaaccgtc
     6901 gcttcactgc gccttgtccg tggattgcta cgacgatccc agtctctcct gcttttaatt
     6961 gatcaagaga agtccagctt tcagaggaag cagtcttttt attgacaaag atttgaccta
     7021 gtatttcccg acttactgcc actcgatgac tttttaccag taaaatggca ttgttgcctg
     7081 ataaattgac gacgacgatt ttacttccgg caacgatccc gatattttgc aaatggcgtt
     7141 ttgttttttc ttctgtttcg attcgttcga cttgataaac gaaattctgc tttgcctgcg
     7201 ctaaggtctg catattgatt cctctcttgt gaaataaatc atgtattaaa atcattcatt
     7261 atatgttcta attttcttac gtgttacgca aataaatgag aatcattctc acatagaata
     7321 ctctcggtaa ttgagaatgt caattatact tgtgatatta tgagcgaatc tttagtattg
     7381 atagataaaa atgagaaaaa aatatttctt catagttttc cacaattttt tctctattaa
     7441 atttgctatt ttcccacacg atacttgttt tcagctcttt tttcaaaaac acaaaactta
     7501 gtattccaca gtttccacaa cacaatatgt agtgtttgtt gtttgacttt tttactaaga
     7561 gttttatact atctattata gataataaga atgtgttaga ggaggcactc accatgaacg
     7621 taaaaatctt ttctaaaaat aattgtatgc aatgtaagat ggtcaaacgg tttttaacag
     7681 aaaatcaaat tgcttttgaa gaagtcaata tcgatgaaca gcctgaagca gtagactggt
     7741 tgaaagcaca aggattccaa agtgttcctg tcattacttc tgatgcagaa acagttatcg
     7801 gattccgtcc tgatcagttg cgtaaacttg ccagctaaca tgactaaaag aatcaaaacg
     7861 tgatacatgg atttgaaggg cttgagacag caccagtttt tgtcgcaaac ttccaaatcc
     7921 ttttttaaag cttaaaaaca atgcaatgat ttgcaatcaa gcatcatcaa atacgaaatg
     7981 aaggttgggc gtacgtatga gtcttaaaaa tttacaagat gtcagttatt tcaagctgaa
     8041 taatgaaatc aatcggccag tcaatggtca aatccctttg aataaggata aagaagcttt
     8101 agttgccttt tttgaggaaa atgtcaaacc aaatacgatg acttttccat ctattatgga
     8161 aaaaatcaat tacttgatcg atcaagaata tatagaagca gaattcattc aattgtattc
     8221 accatcattt attgaaaagc tatatcaatt tttggacgag caacattttt ctttcaaatc
     8281 ttttatggct gcttacaaat tttattctca atatgcgttg aaaaccaacg acggttccgc
     8341 ttatctggaa acttatgaag atcgagtagc cttcaatgcg ctttactttg cgaacgggga
     8401 tgaagaatta gcacttgctc ttgcagacga aatgatccat caacgatatc agccagctac
     8461 accttctttc ttgaatgctg gacgtaaacg tcggggcgaa ttggtgtctt gtttcttgac
     8521 tcaagtcact gacgatatga actctatcgg gcgctcaatc aactctgctt tgcaattgtc
     8581 ccgtattggt ggcggcgtag ggattacttt atcaaatctt cgtgaagccg gcgctcctat
     8641 caaaggatat gagggtgctg caagtggtgt cgttccagtc atgaaattat tcgaagatag
     8701 tttcagctat tctaatcaat taggtcagcg tcaaggagct ggcgtggttt atttgaacgt
     8761 tttccatcca gacattattg ctttcctttc agcaaaaaaa gaaaatgcag atgaaaagat
     8821 tcgcgtaaaa actctttctc ttggcgtgat cgtacctgat aaattttatg aattgacacg
     8881 taaaaacgaa gatatgtatt tatttagtcc atatagtgtc gaaaaagaat atggtgtccc
     8941 attctcttat gtaaatatta cagctgagta tgatcatcta gttgcaaatc caaacattcg
     9001 caaacaaaaa atcaaagcgc gtgatcttga aaatgaaatc tcaaaattac aacaagaatc
     9061 tggctatcct tacgtaatca atattgatac agcgaaccgc gagaatccaa tcgatggcaa
     9121 gatcatcatg agtaatttat gttcagagat tttacaagtt caaacgcctt ctgtgattaa
     9181 cggcaaacag gaatatgaag tattaggaac agatatctca tgtaacttag gctcgacaaa
     9241 tatcgtgaat ttgatgcaaa gccctaactt tggtcaatct gtgcgtacga tgactcgtgc
     9301 attgacattt attacagatg catctgatat cgatgtcgta ccaccgatcc aaaacggaaa
     9361 taagctgaat catacgattg gattaggtgc catgggctta cacacttatc ttgcaaaaga
     9421 acaaatggaa tatggctcag aggattcatt agactttaca aatatttact tcatgctgtt
     9481 gaattattgg acacttgttg aaagcaacaa tatcgctcgt gaaagaaaac aagttttcca
     9541 taattttgaa aaatcagctt atgctgacgg cacttatttc gaaaaatacg taactggaga
     9601 attccagcca aaatcagaaa aagtcaaagc attgtttgaa ggcattttta tcccaactgc
     9661 tgaagattgg aatgctttga aacaagcagt aatgaaagat ggactgtatc atcaaaatcg
     9721 cttggcagta gcaccaaatg gctcaatttc atatatcaac gatacgagtg caagtattca
     9781 tcctatcact cgcatgatcg aagaacgcca agagaagaaa atcggtaaaa tttattaccc
     9841 agcgccttat ctatccaatg agacgattcc gtattacact tctgcttatg atatggacat
     9901 gcgtaaagta atcgatgttt atgcaacggc acaacaacac gtcgatcaag gcatgagttt
     9961 gactttattc atgcgttctg aaatcccaga aggcatttat gaatggaaga caacaacgaa
    10021 gcaaacgaca cgtgatttga atattttaag acattacgct ttccacaaag gaatcaaatc
    10081 catttattac gtacgtacct ttactgatga tgcagaagaa atcggaagca atcaatgtga
    10141 aagctgcgtg atctaatatc atagatagat tcgcttattc atattttaat taaaggagca
    10201 ttctcatgtc agaaacatat tatgaagcaa taaactggaa tgaaattgaa gatatcattg
    10261 ataaatccac ttgggagaag ctgacagagc aattttggct agatacacgt atcccacttt
    10321 caaatgacct agatgattgg cgtacattgt ctcaattgga aaaagataca gtaggacatg
    10381 tatttggcgg tttgacactg ctagatactg tccaatctga aagtggcatg gatcagttgc
    10441 gtaaagatgt ccgcactccc catgaagaag ccgttttgaa caatattcaa ttcatggaat
    10501 ccgttcatgc caaaagttat tcttctattt ttagtacact gaatacgaaa aaagaaatcg
    10561 aagaaatttt tgactggaca aatacgaatc cttatctgca aaaaaaagct gagcgtatca
    10621 atgaaatcta caaacacggt acaccgctag aaaagaaaat tgccagcgtc tttttagaaa
    10681 cattcttgtt ctattcaggt ttttatactc ctctttatta tttaggaaac aacaaattgg
    10741 ctaacgtagc agagatcatc aaactaatca tccgagatga atctgtacat ggaacctaca
    10801 tcggttacaa attccaatta ggattcaacg agttacctga agcagaacaa gaaacgttaa
    10861 aagactggat gtacaatctt ctttatgagc tttacgaaaa cgaagaacgt tatacagaag
    10921 aattatacga tccaatcggc tggacagaag aagtcaagac attcctacgc tataatgcca
    10981 acaaagcatt gatgaaccta gggatggatc cactctttcc agatactgcc aatgatgtca
    11041 acccaatcgt aatgaacggg atttcaacag gcacaagcaa ccatgacttc ttctcacaag
    11101 tcggaaacgg ctatttgtta ggtcatgtag aagcgatgaa agacgacgat tatttgattg
    11161 gattggaata aggatttatt ttaattcaaa aatttttcga aaaataaaaa gagtttagcg
    11221 tacagatatt ttaaatgtac actgaactct tttttatgct tattcacttg tttcttccag
    11281 cacttttgga ctgtctaact tttccgaaac atgttccatt cttctcaata aatagatttt
    11341 ccggatattt aatattatcg tcttaatcac tgcatagaca ggtatgcaaa tcagcatgcc
    11401 taatattcct gcgacacttc ctgctccaat caataccaag atgatcgtca aaggatggat
    11461 attcattgat ttcccaaata acaacggctt gatcaaattt ccatctaatt gttggatcac
    11521 taaaatcgac aacgccatat acaaagcttg aaatggagag ataaacaaac cgacaatgat
    11581 tgctggtacc gctccaataa aagggccgac atacgggata atattcgtga ttccgcaaat
    11641 gaccgcaagc aacaagctat aaggctgatc gaatattctc attgccaaaa agctcattac
    11701 accaataatc aaagcatcta agatcgtact gctgatatag gcagataatg tttcgtttaa
    11761 ttcttttacc gtttggcgta actctttacg aatcgctttc ggaaagaagt gagacaacgc
    11821 atcaataaat ttgtgcccat ccttgaacat aaatagcaaa ataaatggaa cggtaaataa
    11881 caaaataaaa aattgcatca taaatgaaat gatttttgag acacttgcag ataaactgac
    11941 taatatgata ttgaacaaat tactaagaga taaatttgct gatgctaatt gttcttccaa
    12001 attgaaattt ttaaactctt cccgctgcgc caattcattt aaccatttgc ttgtttcatc
    12061 tgcatacatt ggcaagctct gggtcaattg aattgtctgt tccattaact gaggcactac
    12121 attcatgaca gttaaaacaa ctaaaatgat tacgaccaaa aacgtcaata aaaaaccgaa
    12181 cactctcggg atccgatgct tttcgagaaa aacaacgatt ggatcgaaca tataatagat
    12241 aaaaccagca acaagcaatg gtaaaaaaat tgccgaaagc attttcaata ttggactaaa
    12301 aatattcggc atttgtaaaa taaagtacac gccgatgatc gtgagtacta gctccactgt
    12361 ccagaaaaat aattttgatt gtttaaaacg tgattgcata catctcctcc aaggtccttt
    12421 gatacttcta ttctatcatt taacaaagag ttacgcgctg agattttcat ttgcttaaaa
    12481 aaaacaaaaa aaataaacat attttaatga gtagacgagt acttaaacaa aaacacggtt
    12541 tggagtagtg acaaaaatta tactgcagtc cctttttcca aataaacggt gttcaaaagc
    12601 ttgcatcttc gtaataagcc cagccaaacg aaaaatataa ggaactattt ttatttggct
    12661 gggcttatta cttgatgtag gacatctatt ttacaacctc agatcattta ttgcgcaata
    12721 ctgactaaat gcaactttgt gatatttttg tgtacggaca actcctcgat cacatcggca
    12781 taagtgagcc cttttggaag atcaatcgta tagatatttt tgtacactcg gtagtcatca
    12841 acgaatttta cgtcaaaatt cacatcttcg attacgatat ttttctcttc aaaataatcg
    12901 gtaagaaaat ctttggtttc ttttctatgg ataaattgga tttctaactt tttagtcgta
    12961 ggtacatgga tcacgcgttt cactactgtg agtgcaatag caatcccgat aaaactgatg
    13021 atcgcaatgg aatagtaacc catgccgatg gcgatcccta atccagcaat tgcccataaa
    13081 gaagcggcag tcgtaagtcc cgtcaccgat tgtttcgtga cgatgatcgt tcccgcgcct
    13141 aagaaaccga caccactcac cacttgagca atcagccttg cttcatctga acgaatcgtt
    13201 ccagcaagct gtggatactc taaagcatct cttaatgcac cactagcgat ctcaacttgg
    13261 atcaatgcaa tgatacatgc tcccatacaa actaaaatat gcgtacgcat acctgctgga
    13321 cgatttttat attgtcgttc aaaaccgatt gctccgccaa atagcatagc gatccctaaa
    13381 cgtaaaataa tctctggaat tgtcaatacc atatcattca tctaaacacc ctccagtcca
    13441 atatatcatg tctgaaagga gcagacaaaa aaagtgcaat ttttacctct tacgaaaaaa
    13501 ggactgtgac aaaatttttg tcatagtcct ttttatgaat aaacggtgtt caatcagctg
    13561 accctcggta ttactcaaca aacggcaaaa tatggggagc tatttttcct ttgtcttctc
    13621 taatactcag gtcaaaacgc tgatttcaca acctctttag cctactattg aaaattacaa
    13681 cttacttgct gcttcttcat cgatgatcac aacaacattg tcgtgatttt gcaatacact
    13741 tgctggcaaa tgattcgtta caggtccttc aatcatccct ttgattgcat cagctttgct
    13801 ttcgccaaat gccatcaaga cgatttcttt acttttcata attgaaccga ttcccattga
    13861 aacagctttt gttggtacat cttctgcttt atcgaagaat cgtttgtttg cattgattgt
    13921 tgattctgtt aagtcaacta ctgaagtcgt tccgtcaaat gaagcaccag gttcattgaa
    13981 accgatatgt ccattttgcc cgattcctaa gatttggata tcgattggat gtgcatcgat
    14041 gatttgatca tactttttgc atgctgcttc cagatcttct gcttttccat ctggtacaaa
    14101 cgtttctttg aatggttttt tatcaaataa ttggacatcc atgaaatgac ggtagctttg
    14161 ttcatctgaa ccgcctagtc caacgtactc atctaagttt acagaagtca tttcactgaa
    14221 atccaaatcg cttgaagtca tttctttata taaagtaact ggtgtgcttc ctgttgccaa
    14281 tcctaatact tttgcacctt tgttcatacc ttctttgatg atttcaaatg ctttttttcc
    14341 gccttcttca gcgtttttta cacgaatgat ttccatagtg attgctcctt tatattttgg
    14401 tatagcccaa ttatagcatt ctttttttct ttttacaata attagtatag accaaattgc
    14461 atttttttca ttttcttgac aataaatagg aatccgtgtt aggtttcata agatggttca
    14521 atcaaacaat ccatgttgca tgaaaaccaa gcaagtgatt cactgtggac gctttatgtc
    14581 tgcagttttt ttatgaaaaa ggagttatta tgagtatact gacattaaac aacattaccc
    14641 agcaatttgg cgacaaaatc ctctatgaag gtgtcgatct gcaattaaat gctggcgaac
    14701 atcttgggct gattggacaa aacggagccg gtaaaagtac attgattaaa atcatcactg
    14761 gtgagatctt accagatgac ggacagatcc attggcaaaa aaatattcac aaaggttacc
    14821 tcgatcaata tgtggaagtc gatgaaacat taacaatcga agaatttcta aaaactgcgt
    14881 acgcaaaaga atacgaaaag gaagaaaaaa ttgcttttct ttaccaaaca tatagcgaga
    14941 ccttcgatga ttccttgctg gaaaaagctg ggaaactcca aacggaatta gaccaaggag
    15001 tgttttatca aatcgacacc ttagttgctg agatgagcag cgggttgggg atcgatgtct
    15061 taggtttaga ttcactgttg aaaaatctaa gtggtggaca acgttcaaag gtgattttag
    15121 caaaactact tttagaaaac ccagatgttc tgatcttaga tgaaccaacc aatcacttag
    15181 atgatcagca tatccaatgg ctgacgcagt ttcttcagga ttttgacggt gcgtatatcg
    15241 tgatttccca tgaccaagaa tttcttgatc agatcaccac ccatatcgca gacatcgagt
    15301 ttggaaagat tactaagtat actggccatc taaaacaagc attgaaacaa aaggaacaaa
    15361 atcgcgaaag ctatttgcgc caatatcatg ctcaacaaaa acaaatcgaa aagaccgaag
    15421 cttatattcg aaaatacaaa gccggttccc gatcaacgat ggcaaaaagc cgacaaaaac
    15481 aattagataa aatcgaacgg ctgacgcctc cagcttcagc aagtaaagct gtctttgatt
    15541 ttccattctc gcctattgtc acgacattag cagtggaaac aactgattta gtcatcggat
    15601 atgatcgacc gctacttgca cccatcaatt tgaccatccg ctttggtgaa aatattgcca
    15661 ttcgaggctt caacgggatt ggaaaatcta ctttattaaa aacactgatc ggtgagattg
    15721 aaaaaataag tggcgatttc cacttcccag ataacacaaa aatcaattac ttttcacaag
    15781 atctgtactg ggaaaatcca ttagaaacac cactacaata tttaagcagt caatttccaa
    15841 aagcgactat caaagaatta cgtcgccaac tagctaaagc agggttagtt aatcaattag
    15901 caagtgaacc tctcactaca ttaagtggtg gggaacaaac taaggtgaaa cttgcacagt
    15961 tgacaatgaa ccaaggtaat ttactgattc tcgatgaacc gacgaaccat atcgatcaag
    16021 aaacgaaaga aagcttacaa gacgggatac agaaatttcc aggaacagta atcatcgtct
    16081 ctcatgaaca agaattttat caagatcttg tgcaacgagt cattgagatt gaaccaaaat
    16141 aaacgtttga ttgaatagtt gaaaaaaagg agctgtgaca aaagttttgt cacaactcct
    16201 tcttctgaat aaatggtggc caattagctg accttcggta ttagctcaaa aaacggcaaa
    16261 atatgaggag ctatttttat ttggctattc ttattacttg atgcagaaca gcttttcaca
    16321 acctcttttc gtctattttt tattttcgag atttctcttt cctttaaaaa caactgtttg
    16381 aaagaagaac gcacatcctt gaaaaacaag cccgctaacc gttacaccta accagccata
    16441 ctgctgccac attgtcgtcc ctagcaatga accagccgca cctccaataa agtacataaa
    16501 cataaataca
//
LOCUS       DAXQKX010000055        16506 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.056, whole genome shotgun sequence.
ACCESSION   DAXQKX010000055 DAXQKX010000000
VERSION     DAXQKX010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16506
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.056"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(321..1103)
                     /locus_tag="ACF3MF_002082"
     CDS             complement(321..1103)
                     /locus_tag="ACF3MF_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928042.1"
                     /translation="MENSSNSAEVNVSTSTSEVVKCSQETTSLPEELLGDWQINNKDA
                     GIEISDSKAVFRIGRSQVESKDYYVDVNNKMLLHVYFSFEYDSVKYIEVSIERTGYSE
                     FISKSVGILTMHTKDGQYISLGVKRVSGENNETEAVTEQTMDERIDSSKSNETEVDTG
                     KTIDERIDSFIETYTAIPPTWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNA
                     VTEQVGKDIPLRLLENGKKDYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(1168..2004)
                     /locus_tag="ACF3MF_002083"
     CDS             complement(1168..2004)
                     /locus_tag="ACF3MF_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFE3928043.1"
                     /translation="MRVIKTLNNSLILCLDKQGKEVILMGKGIGFQLKKGDLVPADKI
                     QKVFKLDSLSDALKKDYIKLFEAAPDDLIICVKRIIDYANAKFDFKLNKSLFFTLVDH
                     LKHAIERSQKGIVFQNRLLIEIQKYYPKEFEIGCYAIQLINKKMNVQLPEEEAGNIAF
                     HIVNAQSEQANMEETMLSVRALKDILAMLGYLFPEKKVDKDSMLYLRFVTHLQFFIAR
                     MIKKEELPEKDDFLLASVKQRFPKEYRAALKIKEYVQEEMGASANQDELLYLTLHISR
                     VY"
     gene            complement(2022..3431)
                     /locus_tag="ACF3MF_002084"
     CDS             complement(2022..3431)
                     /locus_tag="ACF3MF_002084"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFE3928044.1"
                     /translation="MQYKQLSAFPEKFLWGASISAYQAEGAYQEDGKQPSIIDKYQHT
                     EGVANFEVASDFYHHYKEDIQLFKELGLKAFRFSIAWTRIMDIENNKTNQKGISFYHQ
                     VIDECLNQGIEPIVTMYHFDLPYFLEEQGGWLNRATIDYFVDYVQVLLTEYGDKVNYW
                     LTINEQNTMILHPGAIGLPPSGELPSKKELFQINHHVLLAQARVIHLYHQLNLKGKIG
                     PAINLTAMYQATSSPEDAIAAHNWETLRGWSFLDVAVRGKYNYLFENYLNDRGLYPKI
                     EAEDQAILSSGKPDFIAINYYSTATIAASKNDGSDVSARAGDQQIMLGEEGVYRAAEN
                     PYVDKTPYGWVVDPTGLRLTLRKLYDRYDLPILITENGYGAPDIVEEDRRINDQDRID
                     YLAKHILAIQAALTDGVDVFGYLPWSAIDVVSTHQGFNKRYGFIYVDRTDENLKELKR
                     IKKESFFWYQKVIARNGLA"
     gene            complement(3445..5268)
                     /locus_tag="ACF3MF_002085"
     CDS             complement(3445..5268)
                     /locus_tag="ACF3MF_002085"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFE3928045.1"
                     /translation="MDYREVGRNVLQQVGGKENVVSLTHCATRLRFELKDKRKADTKA
                     LEKTLGVISVVDSGGQYQVVIGNEVQTAFKEIQKEVGTSIKKGPSSDNQESIISRLIS
                     VISTTFTPMIPAITGAGMVKAILAVLTLTGVLSDSSQTYIILNTIADAAFYFMPVLLA
                     YGAAIKFDVNPILAITVAGILLHPNISQLFSTGDAVSFLGIPVLAADYAGSVLPIIFT
                     VWIMSYVEPFADRISPSFIKFFTKPMLVFLIMGPLALVVIGPFGTLLNDLIAMGAEWI
                     NGKAAWLIPFLMGGLQPFLVVTGTAWAMTPIATMQLSSTGSEMINGPGMLASNIAQSG
                     ATFAVAAKTKNKELKQLAVSTGITALMGITEPSLYGVTLKLKKPLVASMIGGAIAGLY
                     AGLSGLVRYAFVSPGLAALPAFIGENPMNIVHAIITCVIAFVATFIIAYLIGFDDTSD
                     ESEQTAIAEAVIVENPVKGTVCPISEVNDAVFSKGLLGKGVAIHPEENSIYSPVEGEV
                     ITILESKHAIGLRSKEGIELLIHVGIDTVNLKGEPFEVFVKAGDQVSAGQLLINADFA
                     AIRNAGYDDTVIVVVTNSENYAGISEASGSLKEHEPLMQIS"
     gene            complement(6111..6437)
                     /locus_tag="ACF3MF_002086"
     CDS             complement(6111..6437)
                     /locus_tag="ACF3MF_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928046.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKAILDNGSAININIEYYPKKDRIYVEIPYA
                     EVLMLN"
     gene            complement(6483..6845)
                     /locus_tag="ACF3MF_002087"
     CDS             complement(6483..6845)
                     /locus_tag="ACF3MF_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HFE3928047.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGSLYREKDEKMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            complement(6882..7097)
                     /locus_tag="ACF3MF_002088"
     CDS             complement(6882..7097)
                     /locus_tag="ACF3MF_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFE3928048.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPMNELFSDVFNKVNS"
     gene            7224..7559
                     /locus_tag="ACF3MF_002089"
     CDS             7224..7559
                     /locus_tag="ACF3MF_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFE3928049.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(7635..9632)
                     /locus_tag="ACF3MF_002090"
     CDS             complement(7635..9632)
                     /locus_tag="ACF3MF_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928050.1"
                     /translation="METSMINIPIYVDQEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENIEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKIHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVGDNSVKNALIKNRGYFVKQGFTLERASKDIKKLYNVKASSSFLIYLAKGAGI
                     DETIKELILSGAGIVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(9730..10005)
                     /locus_tag="ACF3MF_002091"
     CDS             complement(9730..10005)
                     /locus_tag="ACF3MF_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3928051.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            10237..10971
                     /locus_tag="ACF3MF_002092"
     CDS             10237..10971
                     /locus_tag="ACF3MF_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFE3928052.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            11010..12152
                     /locus_tag="ACF3MF_002093"
     CDS             11010..12152
                     /locus_tag="ACF3MF_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFE3928053.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(12486..13397)
                     /locus_tag="ACF3MF_002094"
     CDS             complement(12486..13397)
                     /locus_tag="ACF3MF_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928054.1"
                     /translation="MGERTFEDVKDYVELQSQEKCTVLSAKPEQEFNDLGTEVTVWNV
                     KTDTDGDWWVVEGDNVPMNLYPQSAYYFGTDEVYSFHMGLMERMRVLHEKYDPEDFVR
                     SVTLDTEIAPQLFRKLKNVATLIDSAEEIEDFQSIGVQCREILIELGNHIFIADMAGT
                     KEQPQKSNFKKKAELFIQFYLTGSDNSDYRSIIKKLTESTWDYANKLTHSSTTTKYEA
                     STCVMLVTSLVGVYENITQKVFDPVSQYICSSCKSKKLTIDSDDSDENGMVESLYLKC
                     EECGDITKVVFLTSDKDSSYTKGKIIE"
     gene            complement(13502..14932)
                     /locus_tag="ACF3MF_002095"
     CDS             complement(13502..14932)
                     /locus_tag="ACF3MF_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928055.1"
                     /translation="MDDIKEVFLEVLSRYIQDNLLEYQNNGKKYEFSFDIKNYNDSLH
                     VVFQYNKAGKIGITDVHSFQIFLNEINIEASKSHLNYTTILDTNSLFFSKKLLPYLHS
                     YEWALRKLIYLLAPTYFDNWTKDSIPDEMISAVKGKQKQAIGKYDLENLLQWIDLYDF
                     EEYLFGENYLFISTGNEKNIVRYKEIIVEELLNLFRETDDLSLSDPFSLWSEVFSKYM
                     YVDLEEIRKDMELIREGRNIVSHNKEIKYSLYKDLIKNLKKYVKQLNEAFKKILIGEI
                     ADEKLFDMTNDFEAYIGNHYSNINLPNATKLLTSLSAMTVLNTDSTKKMMETIGPALS
                     VQRAVMQNIDTEGFRRATEGMKQSLSAMTVLNTDSTKKMMETISSALSAQRAVMQNID
                     TEGFRRATEGMKQSLSAMTVLNTDSTKKMMETIGPALSAQRAVMQNIDTEEFRRATER
                     MKQSLSPKQALKSDYKIADDIEDSNK"
     gene            complement(15101..16030)
                     /locus_tag="ACF3MF_002096"
     CDS             complement(15101..16030)
                     /locus_tag="ACF3MF_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928056.1"
                     /translation="MRSDSRFFVSNLQDDELIRQIDSLLETITESDKRIFLNYVELTR
                     HIIELDKLFNVFRYNLTNLLKHFTIFTNDLIESTGEKLTEDQYYYQINALTINLISSA
                     KTLTESIEVCMKNFLAEKDFKSFKNKILSKPYDEHFSYRFLLHVRNYSQHGHLPVNIE
                     QQRVYFDLDEILTMPHFDLNEKLKSEIDEIKEDISARFEDFPRISYVYTIAKFNLITT
                     EIYLNYLKEVKPILMEMDKEKNELLLNTKFKLTNSDGKSSDVVFYDFDGENYHCFNRT
                     DNSLSMYASIKKEVKKILREEEQYYKEIKNKNQ"
     gene            complement(16278..>16506)
                     /locus_tag="ACF3MF_002097"
     CDS             complement(16278..>16506)
                     /locus_tag="ACF3MF_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928057.1"
                     /translation="QYDMIYDFSSSLDLFELEAEIIENSREKNGKIIISVEKFNELFS
                     ETFEIDPDYYQPQEVFREFRNQIIRSSNIEN"
BASE COUNT         5286 a         3208 c         2411 g         5601 t
ORIGIN      
        1 atctttagaa ccatttcaga tacatatgaa acaattacat atgatttttt cataaaaaaa
       61 cagtactgtc tagtagtata aaatatacaa atttcttaaa aattttttca ctaaaatcac
      121 tacctgaaac agtctaaaac acttatatat caacgtttaa tgaaactatc tccgtttcat
      181 ttcagataca aataaatata gtcgggctcc aaatccgaaa aaaaataccc ccagtagctt
      241 atcctaagct actggagatg tataagtacg gtcatataac aacggggtag ggtaaataaa
      301 tgaaaaagat ggaagaatca ttattcaata acttttttaa atacttcgtt gtaatcagtt
      361 acctgtccgt tcttaaatac cacagaataa tcttttttcc cattttcaag taaccgaagt
      421 ggaatgtctt taccaacttg ctctgtcact gcattactga tacctgttag attagctaat
      481 aaatctgata aagattgagc atctgtagaa atctctgtat cagtatttat cgtgattcct
      541 ttatcttcat ttacaagctt ccaagtaggt ggtatagctg tgtatgtttc gatgaatgaa
      601 tcaattcttt catctatcgt cttcccagta tctacttctg tctcattact cttagatgaa
      661 tcgattcttt catccatcgt ctgctccgta actgcttctg tctcattatt ctcaccggaa
      721 actctcttca cacccaaact tatatattgt ccatctttag tgtgcatagt taaaattccc
      781 acgcttttac taataaattc actataacca gttctttcaa tagagacttc aatgtatttc
      841 acactatcat actcaaaaga aaaatagaca tgtaaaagca ttttgttgtt tacatctaca
      901 taataatcct ttgactctac ttgagacctt cctatacgga atacagcttt actgtctgat
      961 atctctatac cagcatcctt attattaatc tgccaatctc caagtagctc ttctggcaag
     1021 ctagtagttt cttgtgaaca ctttaccact tcactggtag aggtcgaaac attcacctcc
     1081 gcactgttag aagaattttc caaggaatca ggagccttag cacaaccaac aagtctttat
     1141 atattgtgca gccgatattt tcttcattca gtacaccctt gaaatatgca gtgttagata
     1201 aagcagttcg tcctgatttg ctgaggcacc catctcttct tgaacgtact ccttgatttt
     1261 caaggccgcc cgatactctt tcggaaaacg ctgcttcact gaagccagca aaaaatcatc
     1321 cttctccggc aactcttcct tcttaatcat tcgggcaata aaaaactgta aatgcgtcac
     1381 aaatcttaag taaagcatcg aatctttatc aacctttttt tcgggaaaca gatatcctag
     1441 catagccaag atatccttta gtgctcttac cgagagcatg gtttcttcca tatttgcttg
     1501 ttcactttgg gcatttacaa tgtgaaacgc aatgtttcca gcctcctctt ctggcaactg
     1561 aacattcatt tttttgttga tcaattggat agcatagcag ccgatctcaa attcttttgg
     1621 gtaatacttt tgaatttcaa tcagcaggcg attttgaaaa acaatgcctt tttgactgcg
     1681 ttcaatggca tgcttcaagt gatcaaccaa ggtaaaaaat agacttttat tcagcttaaa
     1741 gtcaaacttg gcgttggcat aatcgataat tcgcttgacg caaataatta gatcatccgg
     1801 agcagcctca aacagtttaa tgtaatcctt ttttagagca tcagaaagtg aatctaattt
     1861 aaatactttt tggattttgt cagccggaac caaatcgcct ttctttagtt gaaatccaat
     1921 ccctttcccc atcaaaatta cttctttgcc ttgcttatct aagcaaagaa ttaaactgtt
     1981 gtttaacgtt ttaattactc tcattagatt caccgttctc tctaagctaa gccatttctt
     2041 gcgattactt tttgatacca aaagaagctt tcttttttta ttcgttttaa ttctttaaga
     2101 ttctcatcgg ttcggtcaac atatataaaa ccataacgct tattgaagcc ttgatgggta
     2161 ctaacaacat caatcgctga ccaaggtaaa taaccaaaaa catctacacc atctgttaaa
     2221 gctgcttgaa tagccagaat atgtttggct agataatcaa ttcgatcctg gtcattaatt
     2281 cgtctatctt cctcaactat gtcgggtgcc ccatagccat tttcagtaat taaaataggt
     2341 aaatcatagc gatcgtacaa tttcctcaat gttaatcgta gtccagtagg gtcaactacc
     2401 cagccatatg gcgttttatc tacataagga ttttcagctg cccggtagac accttcttct
     2461 cccaacatga tctgttgatc ccccgctcta gcggaaacat ctgatccgtc atttttgctg
     2521 gcagcgatgg tggcagttga ataataatta atcgcaataa aatcgggttt accggaggat
     2581 aaaattgcct gatcctctgc ctcaatttta ggatataatc cacgatcatt caaatagttt
     2641 tcaaacaaat aattgtattt tccccgaact gctacatcta agaaagacca gcctctcaat
     2701 gtttcccaat tatgggctgc aattgcatct tctggactgg aggtagcttg atacatagcc
     2761 gttaaattga ttgctggacc gatttttcct ttaagattca actgatgata caagtgaatt
     2821 actctagctt gagctaataa aacatggtga ttaatttgaa agagttcttt ttttgaaggc
     2881 agctctccac ttggtggcaa accaatcgct ccaggatgaa ggatcatcgt gttttgctca
     2941 ttaattgtca gccaatagtt caccttgtca ccatactcag taagcaatac ctgtacatag
     3001 tccacaaaat aatcgatagt tgctcgattt aaccaaccgc cctgctcctc tagaaaataa
     3061 ggtaaatcga aatggtacat ggtgacaatc ggttcgattc cctgattcag gcattcatca
     3121 attacttgat gataaaaaga aattcccttt tgattggttt tattattttc aatatccata
     3181 attcgcgtcc aagcgatgga aaagcgaaaa gcttttaagc ctaattcttt aaacagctgt
     3241 atatcttctt tatagtgatg gtaaaaatcc gaggcaactt caaaattagc taccccttct
     3301 gtatgctgat acttgtcaat aatagacggt tgtttcccat cctcctgata ggcaccctct
     3361 gcctggtagg cactaatgga ggcaccccat aaaaacttct ctggaaatgc tgaaagctgt
     3421 ttgtattgca caaaaatcct ctccttaact aatttgcatc aatggttcgt gttcctttaa
     3481 gcttccgctt gcttcactaa ttcctgcgta attttcactg ttggtcacta ccacaatcac
     3541 tgtatcatcg tagccagcgt ttctaatggc agcgaaatcg gcgttgatta ataattgtcc
     3601 tgctgacacc tgatctcctg cttttacaaa tacttcaaag ggttcccctt ttaaattcac
     3661 ggtgtcgatc cccacatgga tcaataattc aataccttct ttagaacgta gaccaatcgc
     3721 atgtttagat tctaaaatag taatgacttc tccctcaaca ggtgaataaa tgctgttttc
     3781 ttctggatga atggctacgc cctttcccaa tagtccctta gaaaagacag catcgttcac
     3841 ttcagaaata ggacacacgg ttccttttac cggattttca acaatgactg cttcggctat
     3901 tgccgtttgc tctgattcat cagaagtatc gtcaaatcca attagataag caatgataaa
     3961 ggttgcaaca aaggcgatta cacacgtaat aattgcgtga acaatattca ttggattttc
     4021 tccaataaag gctggtaagg ctgctaagcc aggggaaaca aaggcatatc tgactaaacc
     4081 gctcaagcca gcatacaaac cagcaattgc accaccaatc atggaagcaa ctaatggttt
     4141 tttcagcttc aaggttactc catagagtga aggctcagta attcccatta aagcagtgat
     4201 cccagtggac acagctagct gcttcaactc tttgttttta gttttcgcgg ctacagcaaa
     4261 ggtagcacct gattgagcaa tattagaagc cagcattcct ggcccattga tcatttcaga
     4321 acccgtactg ctcaattgca tagtagcgat tggcgtcatt gcccaagctg tacccgtaac
     4381 caccaaaaat ggctgcaaac cacccatcaa aaatggaatt aaccaagctg ctttgccgtt
     4441 aatccattca gcccccattg ctataagatc gttcagcaac gttccaaacg gtccaatgac
     4501 aaccaacgct aaaggcccca taattaaaaa taccagcatc ggcttagtaa agaatttaat
     4561 aaacgaaggc gaaattcgat ccgcaaaggg ctctacatag gacatgatcc aaacagtaaa
     4621 gataatcggt aaaactgatc ccgcataatc tgcagctaat accggaattc ctagaaaaga
     4681 aacggcatcg ccagtagaaa aaagctgtga aatatttgga tgaagcaaaa tgccagcaac
     4741 agtaatcgcc aaaattgggt tgacatcaaa ctttatggct gccccatagg ctaatagtac
     4801 tggcataaaa taaaaggctg catcagcaat agtattcaaa atgatgtaag tttgactact
     4861 gtctgatagt acaccagtca aagtcaagac ggccaaaatg gcttttacca tcccggcacc
     4921 tgttatagct ggaatcatcg gtgtaaaggt ggtagaaatg acactaatca atcttgaaat
     4981 aatactttct tgattgtctg aagaggggcc ctttttaatt gaagttccca cttccttttg
     5041 aatttccttg aaggctgttt ggacttcatt gccaatcacc acttggtatt gtccaccgct
     5101 atccaccaca ctaattacac caagtgtttt ttctaaggct ttcgtatcgg ctttcctttt
     5161 atctttgagt tcaaaacgca gtctggtggc acaatgggtt aagctgacca cattttcttt
     5221 tcccccaacc tgttgcaata catttcttcc tacttctctg taatccatta ttctctctcc
     5281 ttaaagcagt aaaaaagacc aagtcaaacc acgccccaat caacattgaa gtgttagttt
     5341 gtcttggtct tgcctgcata atcagtaaca tgccaataac gttattttgc tgtaatccaa
     5401 taatagcaca ttatgatagc gcaatcaaca gggaatttaa ttttttatct tttcgtttga
     5461 ccgtataggg taatataaca gttagatcac atcaactagg gtatatctgc gtatacttac
     5521 tgctaaaata agtatatcta atattaacta taccagtaaa accattccta cataaccagc
     5581 gggaaattcc caaaatcgtg aaagcatcaa aaatgcatat aacggatcac acaacttcaa
     5641 caattctgct cttgggaaaa attgatgaat ttggtgagta aaggatggaa taaacagcat
     5701 tccaacaata taggcaacaa tagtgatact tgtttttttg gtaaaaatca gtaagcaata
     5761 gccaatttca atcattccga gatataaagg tatcgataga atgatttggg ctagtattct
     5821 taaaaattaa ctagcaaatg tttaaactga tttatttcta atctacatgt agtaagtatt
     5881 tcaattccac caattatcaa taaaaatacc aaacatatcc ataataattt tttctttttc
     5941 atttctttta tattgttata acagtgaata acataaaaat tcccgacaat cattgtaata
     6001 tttttttgtc acctgtatta gtatttaatt tataggaaac tataaaaact ccctagtgaa
     6061 tttacacctt tgggagttcc tgtttggacg gtatgcataa tacatttaaa tcaatttaac
     6121 attaacacct cagcatatgg tatctccaca tatatacggt ctttctttgg atagtactca
     6181 atatttatgt tgatagcact tccattgtct aatatagctt tagcccggta tgtgttatct
     6241 ccattttcat gagtaatcgt cacatcatca catgatcgat ttaagttgta ctgttcttgt
     6301 aaaatctgtg ttaccaatgg ttttgatgac ttctctaatc cagatgtacc tgtcattttt
     6361 gaaaaaataa tacctataat agccaagaca acaataccta taatgacaaa cttcttgttc
     6421 atatttactt tattcaactt tttatctcct atctccaaaa taatttgctc ttatccctct
     6481 tatcagtaca ttgacatccc taaaagtaca ccaaagattg ctccagctac ccctgctatc
     6541 atcaaaatcg tacccatttt ctcatctttt tctcgatata aggagcccat aataacagca
     6601 acagcaccaa atacaacagg aataaatgct aacgatacta ccatagaaat ccaaccaata
     6661 atcaaataca gcttccctgt ctcttgtcca tgtacgattt gttccttcat ttcattaatt
     6721 gtctgctcag tacttttctt tactgtgtct gttccggttg tctcatctgt ttcttgtagt
     6781 gctccacaaa actggcaata cttactttca tctgttattt ctttgccaca ttttctacaa
     6841 tacatgtctt ctcctcctaa aatcattcaa ttgcttatta gttaactgtt tactttatta
     6901 aatacatcag aaaacagctc attcattggt acacttaata tctcagaaag catcttcatt
     6961 tgatagggtt taggaatcgt tctccctgtt tgccacgaac ttacacattg ctgtgtaaca
     7021 ttcatttttt ttgctaactc cgtttgagaa agtccttttt cttttctgta tcggctgaga
     7081 ttacttactt ttttcatgat tctcccctcc tgttttatta tatacaacaa tatgatgtat
     7141 ttcaactcat aaaatataaa aaacttcaaa taccattaca aatacaacaa cttgttgtac
     7201 tatactgaga tgggggtgta ttaatgaaac agaaacaata tgcaaaggtc attagagaaa
     7261 agcgaaaagc tctcgggtgg acacaaaaag aattagctga aaaaatcttc tctacacaac
     7321 aggcagtagc aagatgggaa aattctgtaa cagagcctaa cctcgatagc ttaacagctc
     7381 tttctagagc cctaggaacc cctgtaagcc attttctaga caatgttgtc gtagattatg
     7441 aggaagagtt tttggctctc tatcgttctc ttagcactga agatgcagtt cgaacaattg
     7501 actatatgaa gctattaaaa aggcaagaaa atgaacgcaa tcagctattg aaagattgaa
     7561 aaataaataa cccaccgaac tttaacggtg ggtgtattga gatgaaataa gattaagagc
     7621 tatggataac ctgtctagtt taatacaatt gggtcttttc tcttccttac tctccgtcca
     7681 tcatctcttg ttacacttgt aaattgatac agaggaacta tcccagctcc tgataatatc
     7741 aattctttta ttgtttcatc tatccctgcc cctttcgcta aatatattaa aaaactacta
     7801 cttgctttca cattgtatag tttcttaata tccttagaag ctcgttcaag agtgaatcct
     7861 tgtttaacaa agtagcctct gttttttatt aaagcatttt tcacgctgtt atccccaaca
     7921 ttacgtaggc gttcacaaac agtgttaata agttctttct ctgtcattag atatgtccct
     7981 tgccacgata agccctgtaa aacttcatgt gcttcatcta aaatcaattg tttttccttg
     8041 ctgagttctg atcgggaatt ttgaggaaat actcttttag cctctttttc gttaaaacat
     8101 atcttaaccc attcataaga aaaatattga tatgtaaaat gaattttttc cagaagtgga
     8161 aggatatctt cattcaattt ttgaatcaca gaagttgcat taaaaacgtc taatcgatag
     8221 acattgcttc tcttatgatt aaagtttcct aacgctttct cttcctttaa cctatttagg
     8281 tattcgagca tcttcaaagg aacatcttca tcatctaatt tttttatcaa tcctataaaa
     8341 gtcataagtg atagtaactt attacattta tctatgtcat aagttttacc atagtaagaa
     8401 ctcatttttt tagctaattg ttcccccgac aaaatacaag tcacactttc cttactatca
     8461 tcaaaaaaat taacatcaga aagcaagaca tcatagacac gtcgcatttc ctctagataa
     8521 ttccttattg tcctgaaaag tttgtctttc attgattcaa gagtgtcaaa aagtactttt
     8581 gattcctctt tcaattttcg aaaatgtgta ggatacaagt ctaggttctc taatagccaa
     8641 ttaaatgttt ctacccgact gtctttcttt aaaattagca tcacaactcc aataaaattt
     8701 tcactgatat cacaattact ggaatgacaa taaaaaatgg aatgcccagt tttactggta
     8761 aaaatactag cagagggatt atgatcgttg tgaaacagac atcttaagtt tttacttgac
     8821 ttaagtaatt tattcatatc aatggttaac aatctttcat aaatctcatt aaaagacatg
     8881 tcggaggaat caaacaggca gtctttaaac cactgtttca tttcttcttt gtcgtcattt
     8941 tttatcaact taacaaaatc ggtttcattg actagttcat actctctccc tgaatcactt
     9001 tgacaatttt tagaacatgt catggtaaaa tcaatcggaa gctcagtaat atctaacatg
     9061 ttgtcttcat taattattat cactgcatct gacttatatc ctccaaaaaa cattctattc
     9121 gaagcattta cattgtcatc acacccgggg atgttctttt tcaagtattc gtaaacagca
     9181 accattttac catagtcagt aattgcttct tttaatagaa agacaatctt gtatttttct
     9241 atgttttcag agtaccgaat acttttttgt atcgcaaacg cagaattatg aactaaattg
     9301 atagataaaa ccttttctat gcttaagtat ctactatcat ctttactcaa atctactacc
     9361 ttccccttct catctttaac agtgttatcg acatccagaa taattactct ggtttccaca
     9421 aaactctcct tgtcattgcc tttattcttt gtcttgcttg gaataaatga ttgtgatgaa
     9481 tttagtatct ctacaaactc atctcttgta acttctctat agttatctaa acacctatct
     9541 cttacatcag ttttttcttt ttttgtaact ggcttctcta ataatttttc ttgatctaca
     9601 taaattggaa tattaatcat tgatgtttcc atttgtgttt cctccttata aaattctgtt
     9661 aaagactaaa acatacagat aataaaaaca aactctttat tactatatgt tttagtctta
     9721 tttgtttact caacctttat accgttccat gaaactatca atatcagatt ttttaaatct
     9781 aatgaccgta tcaattttta taacaggtaa cccgtattga gaaacatatt ttctaatcgt
     9841 tcctactgat acacctagat attcacttgc ctgctgatag tccatatact ctagagtgac
     9901 tccagaaata atgtcttcta gcataggctt tagcactgta attatctctt tcacttgttg
     9961 ttcaacttgt atagaaacaa tgctatcaat gatttgtaga gacatatttc cccctccttt
    10021 cgtgattgct tgaacaaatt ttctaagaat tatcttcgta ttttttgctc aaaataaaag
    10081 tattttgtta ttaaccgatt aatcaaacaa aaaatgatta ccagttcatc gacatacaca
    10141 taatacctcg ataaaaaagg ggtgtcaaca gctttgtaaa atttatttac aacacccctt
    10201 ttttgaggta tactaatttt aggaggtgtg gtcaatatga taaaacgtcc accaataaat
    10261 tatttagaac gaaaaaagat actcggaaca aaaataaaag ctataagaaa gagtaaaaaa
    10321 ttaacacaac cagcatttgg tcttatgatt aacaacggtc aattaattga caaaaaaact
    10381 atctacgaat gggagaaggg aacctattta ccaataccag agcgattatc ccgaattgct
    10441 gatttgggaa atatgagtat agaggagtta gtttgtggca atgtagaaga atatattttg
    10501 ggaattattc tttatagaga tagcattgta ctagatggta taacatttcc agataaaaac
    10561 ctgttccagc atcttcgtca acagttccca ccagtacact ctaatttaga tacatggctg
    10621 gatagatatt ccaaattaga accagagatg caagaattta ttgctaacaa gacttgtaat
    10681 aaagttaaaa atgaaaaaat tagtcttttc aatatcttaa aaatagaaga attattcatc
    10741 aatgctattg tagaagaatt tgacaataac attcttttcc tcactagcag tatagaagaa
    10801 ctactagaaa gaatggtaga tgaatggcta cctattcaat tgaaagacat gtcttatccc
    10861 gaagaagctg tgagagaaat tactgataat ataaacaagc tagaacaaac gatttcatca
    10921 attgggaaaa aatacactaa gaaaaaaatg aagggaggtg ataccatcta gtggtaagta
    10981 ctccttgtaa actaagagga gatgatttaa tggcaaaaat atcaaagtac aaaaagaaaa
    11041 acggtcaagt ggcgtggatg tataaaggac acattgccac cgatccacga actggtgaaa
    11101 aaataaatac tacgagaaga ggttttagta gcaaacaaga agctcaaaaa gattatgacg
    11161 agtacagaca tcaaatatta tacggtgtta aaaagaaagc acctgatatg acatttgaag
    11221 acctgtataa tgaatggata actcatcagc gtaccagtgt taaagcttca acaatcgcaa
    11281 tctcagtaag atacgcaaat aatcaaatac ttccagcatt tggtaagctt aaactatcga
    11341 atatctctgt cccatattgt caaaaagtgg tagatgaatg gcacagtaaa tatgaaagtt
    11401 acgattatat gagaaaacag actgcacaaa ttttacgcta cggggttgca atgcaatata
    11461 ttgacaataa tcctatggaa aaaacacttc ttccacgaaa aaaagagtat gagaaaaatc
    11521 gtaaatttta ctcaaaagag gagcttaata atttactgga tgcttttaaa gattttggta
    11581 acatgaaaca atacgccttc ttcagattat tggcatacac aggtatgaga aagagtgaag
    11641 tactcgcttt acagtggaaa gacatagaca cgtttaataa agaactacat gtcaataaaa
    11701 ctcttgctgt agatgaattt ggtaaagtta taattcaatc tccgaaaaca agagcttcta
    11761 gacgagttat ctctttagat actgagactc tttctatcct caacaactgg aaattacagc
    11821 aaaaagaaga gtatttaaaa cttggataca atactagctc taaagagcaa catgttttta
    11881 caacagttaa aaacactcta tacattccaa acactgttaa tgattggtta agatatattt
    11941 tgaaaaaata taacttgcct cgtattacac ctcatgggtt tagacataca catgctagtt
    12001 tattattaga agcaggagaa tctgtcaagg tagttcaaca acgattaggg catgaaaata
    12061 gtaaagtgac attagacatc tatgcacata ttacaaataa tgcacctaag aaaacaggtc
    12121 aagactttgc tgatatgatg gctcatcagt aaaagagctg gtcaaaatct ggtcatttct
    12181 agtatacagg caaaacaaaa aagctagaac ccttatatat caagggttct agctcctata
    12241 acaggtttac ccaacactgc cttccaatga ctcttttcaa tagcattggt acatgattcg
    12301 cgttataaaa gcatttttcc cgctctggta tatatcactg acagcctatc acagcacttg
    12361 atatccccca gaacgtatcc aatatcgtac ccaaaaaagc aggtagagaa gttatttgag
    12421 gtatcaaatt taaaaacgtg tgcactttga attgcgtgat atgtttttga catgatccat
    12481 aatcattact caattatttt tccttttgtg tatgaactat ccttatcact agtcaaaaat
    12541 actacttttg taatatcacc acattcttca cattttaaat acaaggattc aaccattccg
    12601 ttttcatcag aatcatcaga atctatcgtg agttttttac ttttacacga cgaacatata
    12661 tactgtgaga caggatcaaa gactttttgc gttatgtttt catacacacc aaccaaagac
    12721 gttacaagca ttacgcaagt tgaggcttca tacttagtag ttgtactaga atgagttaat
    12781 ttattagcgt agtcccatgt tgattcagtt agttttttta taatacttcg atagtcagag
    12841 ttatcggaac ctgtcaaata aaactgtata aaaagttccg cctttttttt gaagtttgat
    12901 ttttgtggtt gttctttagt acctgccata tctgctataa agatgtgatt accaagttcg
    12961 attagaattt ctctacactg aacaccaata gattgaaaat cttcaatttc ttctgcactg
    13021 tctataagag tagcaacatt ctttagcttc cgaaagagtt gtggtgcaat ctctgtatca
    13081 agagtaacgc tccttacaaa gtcctctgga tcatattttt catgtaaaac tctcattctc
    13141 tccattaaac ccatatgaaa cgaatatacc tcgtctgttc caaaatagta tgcactttgc
    13201 ggataaaggt tcataggaac gttatcaccc tcaacaaccc accaatcgcc gtcagtatcc
    13261 gttttgacat tccaaaccgt tacttctgta ccaagatcat taaattcctg ttccggcttg
    13321 gcacttaaca ccgtacactt ttcttggctc tgcaattcta catagtcttt aacatcttca
    13381 aaagttcgtt cacccattat ttacctccat gatttttacc aaatagattg tatttttcta
    13441 gttttatttc acctctctaa ttcttttaat agtttattaa ttggaaaaag ttctggactc
    13501 tttatttatt actatcttca atatcatcag caattttata atcggatttc aatgcttgct
    13561 ttggtgatag agactgcttc attctctcag ttgctcgtct gaactcctca gtatcaatgt
    13621 tttgcatgac tgctcgttga gcggataatg ccggaccgat tgtctccatc atttttttag
    13681 tagaatcagt atttaatact gtcatcgctg atagagactg cttcattccc tcagtcgctc
    13741 gtctgaaccc ctcagtatca atgttttgca tgactgctcg ttgagcggat aatgccgaac
    13801 tgattgtctc catcattttt ttagtggaat cagtatttaa tactgtcatc gctgatagag
    13861 actgcttcat tccctcagtc gctcgtctga acccctcagt atcaatgttt tgcatgactg
    13921 ctcgttgaac ggataatgcc ggaccgattg tctccatcat ttttttagtg gaatcggtat
    13981 ttaatactgt catcgctgat aaagacgtca ataatttagt agcgttgggt aggtttatat
    14041 tactataatg attccctata tatgcttcga aatcatttgt catatcgaaa agtttttcat
    14101 ctgctatttc accaattagt attttcttaa atgcttcatt aagttgtttc acgtatttct
    14161 ttagattctt tatcagatcc ttatataaag agtatttaat ctctttatta tgactcacaa
    14221 tattccttcc ttctctgatc aattccatgt cttttcgaat ttcttctaaa tcaacataca
    14281 tatacttgct aaatacttca ctccataatg aaaaaggatc agatagactt aaatcatcag
    14341 tttctcgaaa taaatttaac aattcttcta cgattatctc tttgtacctt acaatatttt
    14401 tctcatttcc agttgaaata aataggtaat tttctccaaa taggtattct tcaaaatcgt
    14461 ataaatctat ccactgtaaa agattttcta agtcatactt gccgattgct tgtttttgtt
    14521 ttccttttac tgcagaaatc atttcgtctg gaatagaatc tttcgtccag ttgtcgaaat
    14581 atgttggagc caataaatat atcaattttc ttaaagccca ttcataacta tgcaaatatg
    14641 gtagtaattt ttttgaaaaa aataatgagt ttgtatctaa aatagtagtg taatttaaat
    14701 gtgacttgct cgcttcaata ttaatttcat ttagaaaaat ttgaaatgaa tgtacatcgg
    14761 ttatccctat tttaccagcc ttattatact gaaatactac atgtaacgaa tcattataat
    14821 ttttaatatc aaaactaaat tcgtattttt ttccgttatt ttgatattct aaaaggttgt
    14881 cttgtatata tcgtgataat acttccaaaa aaacttcttt aatatcatcc attttgcctt
    14941 gtttagggta atataaatat tcaacaactt gcttgctaat atgtcctcgc cttcttttct
    15001 ttcaacgatt taaaattttc caaataactt gataactact aagtaagcct caaacaacaa
    15061 ccacaaatga atttttcact aatattgatg attgtgatat ttactggttt ttatttttta
    15121 tttctttata atattgttct tcttctctta atatcttttt aacctccttt tttatgctag
    15181 catacatcga taaactattg tctgttcgat tgaaacaatg ataattctct ccatcaaagt
    15241 cataaaaaac cacatcactt gattttccat ctgaattagt taacttaaat ttagtattga
    15301 gtagcaattc atttttttct ttatccattt ccatcaaaat tggtttaact tcttttaaat
    15361 agttcaaata tatttcagtt gtaatcagat taaactttgc aattgtgtac acatatgaga
    15421 tacgtggaaa atcctcaaat cgagcagata tatcttcttt aatttcatct atttctgatt
    15481 ttaatttttc attaagatca aaatgaggca ttgttagaat ttcatccaaa tcaaagtata
    15541 ctctttgttg ttcaatattt accggtaagt gaccatgctg agaataattt ctaacatgta
    15601 ataaaaatct gtacgagaaa tgttcatcat aaggcttact cagaatttta ttcttaaaag
    15661 atttaaaatc tttttctgct aaaaagtttt tcatacaaac ttcaatggat tcagtcaaag
    15721 ttttggctga actaattaag tttatcgtca aagcatttat ctgataataa tactggtctt
    15781 ccgttaattt ttcacctgta ctttcaatta aatcattagt aaaaattgtg aagtgtttga
    15841 gcaaattagt taaattatat ctaaacacat taaaaagttt atccaactct ataatatgac
    15901 gtgttaattc tacataattt aaaaatattc ttttatcaga ttctgttatt gtttctaata
    15961 atgaatcaat ctgccttatt agctcgtcat cttgtaaatt actgacgaaa aacctactat
    16021 cacttctcat aattatattc tcctaatatg attttttcaa aataatcaat atgtaacata
    16081 gaagtatact ctattgttac ataccttatt tcttattata tcagtatttc tctgtgacac
    16141 ataagggtgt aacataatta ttttaaacga aatgactaca agtagtcatt gaagcaaatc
    16201 tccataagac atttgtaaaa tcttttaaaa agaagcgtcg aaagaaggaa cttttcttca
    16261 acgcttcttt tattgactca attttcaata ttacttgaac gaataatctg atttctaaac
    16321 tctcgaaaaa cttcttgtgg ttgataatag tctggatcta tttcaaatgt ttctgagaat
    16381 aattcattga atttttctac tgaaataatg attttaccat tcttctctcg actgttttct
    16441 attatttctg cttctaattc aaataaatct agtgacgaac taaaatcata aatcatgtca
    16501 tattga
//
LOCUS       DAXQKX010000056        16212 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.057, whole genome shotgun sequence.
ACCESSION   DAXQKX010000056 DAXQKX010000000
VERSION     DAXQKX010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16212)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16212)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16212
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.057"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            226..894
                     /locus_tag="ACF3MF_002098"
     CDS             226..894
                     /locus_tag="ACF3MF_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HFE3928058.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(1094..1480)
                     /locus_tag="ACF3MF_002099"
     CDS             complement(1094..1480)
                     /locus_tag="ACF3MF_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928059.1"
                     /translation="MRRTAKKFIDYNEYRDRPFGLKWGTAFAMEELVNGIKKNEEEAR
                     KQPLPKQQMTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYF
                     MIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(1452..2834)
                     /locus_tag="ACF3MF_002100"
     CDS             complement(1452..2834)
                     /locus_tag="ACF3MF_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HFE3928060.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            complement(2990..4177)
                     /locus_tag="ACF3MF_002101"
     CDS             complement(2990..4177)
                     /locus_tag="ACF3MF_002101"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HFE3928061.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            complement(4184..5215)
                     /locus_tag="ACF3MF_002102"
     CDS             complement(4184..5215)
                     /locus_tag="ACF3MF_002102"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFE3928062.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            complement(5261..6685)
                     /locus_tag="ACF3MF_002103"
     CDS             complement(5261..6685)
                     /locus_tag="ACF3MF_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015486 -
                     glycoside-pentoside-hexuronide:cation symporter activity
                     [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside-pentoside-hexuronide (GPH):cation
                     symporter"
                     /protein_id="HFE3928063.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMED"
     gene            6860..7765
                     /locus_tag="ACF3MF_002104"
     CDS             6860..7765
                     /locus_tag="ACF3MF_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HFE3928064.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLVVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            7856..8533
                     /locus_tag="ACF3MF_002105"
     CDS             7856..8533
                     /locus_tag="ACF3MF_002105"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFE3928065.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            8530..8700
                     /locus_tag="ACF3MF_002106"
     CDS             8530..8700
                     /locus_tag="ACF3MF_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928066.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            8814..9710
                     /locus_tag="ACF3MF_002107"
     CDS             8814..9710
                     /locus_tag="ACF3MF_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFE3928067.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(9765..11135)
                     /locus_tag="ACF3MF_002108"
     CDS             complement(9765..11135)
                     /locus_tag="ACF3MF_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFE3928068.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            11373..12119
                     /locus_tag="ACF3MF_002109"
     CDS             11373..12119
                     /locus_tag="ACF3MF_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFE3928069.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQPVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            12116..12955
                     /locus_tag="ACF3MF_002110"
     CDS             12116..12955
                     /locus_tag="ACF3MF_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFE3928070.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            12956..13906
                     /locus_tag="ACF3MF_002111"
     CDS             12956..13906
                     /locus_tag="ACF3MF_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HFE3928071.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            14047..14799
                     /locus_tag="ACF3MF_002112"
     CDS             14047..14799
                     /locus_tag="ACF3MF_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928072.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            14818..15969
                     /gene="queG"
                     /locus_tag="ACF3MF_002113"
     CDS             14818..15969
                     /gene="queG"
                     /locus_tag="ACF3MF_002113"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0052693 - epoxyqueuosine reductase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HFE3928073.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
BASE COUNT         5267 a         3019 c         3250 g         4676 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacggt tgtgtaaaaa tatcatttta gagcataaaa
       61 aaaaggagtg gatttctcca ctccaaaaaa gtctaacttt tgggggtcac tacagtgtca
      121 cagtcctttt tttagtaaaa ggatacattt cttccttgta tattccatgc gtgttcgtga
      181 gaaagcatat ataatttaat taacagatag ttagggggag aaaaaatgat tttttcaatt
      241 acaatgaaac tggtgttcgg gttgatcggt ttattattag tggtacgttt gcttgggaag
      301 aaatccatgt cagaaatcac accgtttgat ttagtctata cgcttgtttt aggtgggatc
      361 ttagaagaat caacctatga tgacaatgtc catgtagggc atgtcctatt tgccattgcg
      421 ctttgggcag taatgattta tggtatcgaa cgtatcgtcc aaaaaaatga aaaggtcaat
      481 cgttgggtca aaggcgagcc atctgttcta atcaaagacg gcgtcatcaa catgacagag
      541 ttgacaaata accatatcga gatggagcag ttgcgagcaa tcttaagaca gcaagaatgc
      601 ttttttcttg aaaatgccaa acatgttatc ctagagaatg ccggtcaaat gagtgtattg
      661 aaaaaatcag atgaagacaa agctttatcg atcctgcttg tagatgaagg gcaaattcag
      721 cataaagtgc ttcagtccaa tcaattgact gaagcatggc ttatggagaa cttgaagaaa
      781 gaaggctatg cagatgtaaa acagctgatt tatgttgaat ggtcagaaga aaaagggctc
      841 tacatactaa ataaagaaga cgtcatgcat gaatcttacc gaatagatgg atagatagac
      901 agaggttgtg aaatcagcgc cttggcttgt tactcaaaac taagcgactt tttcacaacc
      961 tctgatatct aatatacgtt gttccagaag ttgcttcttc gaaaaataag ccaaaattcc
     1021 acaaaaattt aagaagcaat tttcgaaaaa tcctttctta ttttttgaag ttgatcactt
     1081 ctgtcacaac ctctcatgtc acaaaccatt tttttgtttc ctttaactca atataccgta
     1141 cgtcttccca caatatcggc tgatggtcaa tcataaagta atcttcatag gcttcaccaa
     1201 tgaagtgccc ttcgacctca tccaagagtc ttccaaattc atcttttaaa ttgagctgaa
     1261 tgattactgc tttacgagat aaaaaggctt ctgtcagtat actatcgatt tcttgcaatg
     1321 tcatttgttg tttaggaaga ggctgtttgc gtgcttcttc ttcatttttt ttgataccgt
     1381 tgactagttc ttccatcgca aaagcagtcc cccattttaa tccaaatggc cgatctcgat
     1441 actcgttata gtcaatgaat ttttttgctg tccgtctcat cttttccacc ttctaatcca
     1501 ctcataccac ctgcatgccc gccaacgaga gaactacgtg cgatggcgcg tcctccttgc
     1561 aagagactat gcgcatggat gattgattga aagccgtatt tttttctaat cgtatcgaca
     1621 acaaaatcaa ctttcgcttc atttatctgc ttttcaggat cttcaaaaag gttaagctgt
     1681 aaacctgtcg cgtatacgag gtcggaacag ttcacgccta cacgccgaat atcctggtag
     1741 tggtaatgct ggtggaaaat ggtcaataaa gcatctgcta gatctctgct agcatttgtc
     1801 gcttcgattt tcatttgctg gtgaaacccg gtcttgccat ttggatcaag atagcctaaa
     1861 gagtatccta cccataagct gactacttgt gtttttgctg cagatcgtct caagcgagtg
     1921 ccgacttggt cggccatttc tttgataacg atctcgattt cttctcgtct tgtataatct
     1981 ctatctagga tttgactatt tccgatactt tttgattttg gtgtatattc ttgtcccaaa
     2041 aaacttcgat cgatgcccca agcatgggca taaagctgag taccgatgac ccctagcttg
     2101 cttttcaagt gataataatc cgcgtgagct aaatcataaa cagaatgtat acccatttgt
     2161 ttcagacgtt ttgctgttcg tttgccgatt ccccaaaagt cagtgatatc tgagattttc
     2221 cataactttt ctggtacatc ttcataacgc cattcagcaa acatttgctt tccgtctttt
     2281 gagccattgt ctaaggctag tttagcaagt agcgggttat cgccaattcc tatagtcgtg
     2341 tagattccgg tctgctcaaa cacatcttta tggatcagtt tagccatgtc gtacgcattt
     2401 gttttaccaa agagtgccat gctatttgtt acatcaagga agctttcatc gacggaatag
     2461 acatgatggt tcgcttcgtc tgcatatttt ttatagatag aattgatttc tctgttcttt
     2521 tccatataat aggccatcct tggggcaaca atatataaat cacttggata ggggaaggga
     2581 agatctctgg cacggctgat attggtgatg ccgtaagctt tttttgctgc aggactggaa
     2641 gccaagatta atccgctacc ccgtgtttct gtcgaatcgg acggatagga catgactact
     2701 aatttagttg taaggggatc aagatccttt tcaacgcact ctacggaggc gtaaaaagat
     2761 ttgcagtcaa tacataaaat atctcttgaa ggttcttttt cataaacaaa taccggattt
     2821 tgattcgccc acataacaat cacctcttca acacaattag aacacacgtt ctctttccgt
     2881 gtcaataaaa aacagcaatt ttcaaatacg agcaaaaggc tcacatttgg aaattgctga
     2941 gaggttattt ttatctattt gtttttagct gagatcgttg atttttttat caaacatgaa
     3001 cagcttctgg atcgatcttt gttgtcccat ttccaatgtg tgcaacataa aattccggag
     3061 catagccgac aactttcatg tattcatcat agacattgtt tttgaaggca ggtatatttt
     3121 cttctttgac aagagcaatc gcacagccac caaatccagc tcctgtcatt cgtgcaccta
     3181 agacaccttc ttgtttttga gcagcatcta ctagtgtatc taattcgatc ccagttactt
     3241 cataatcata gcgaagagag tggtgagaat catttaacag ttgaccaaat gcttctaagt
     3301 tcccagcttc taattcagct tttgccttca aagtccgctg attttcagaa acggcatggc
     3361 gagctctgcg tatcaatgta tcatcgccga tttggtcaat agttgattca aattcttctt
     3421 catctaagtc tcctaaagaa gagataggca aagttttttg caaacgtgcc aaggcttctt
     3481 cgcattcgct acggcgttca ttgtattttg aatctgccaa ttcccgccgc ttattcgtat
     3541 tcatgatgac gattgcataa ccatctagtt tcactggaac catttcgtat ttcagcgtat
     3601 ttgtatctaa taagattgca tgatctagct caccgaagcc gatggcaaac tgatccatga
     3661 tacctgaatt gacaccgatg aattcatttt ctactttttt acctgtttgg actagttcca
     3721 agcgatctgt ttttaaatca aacagatctt ctaatacaac acctactaat aattctaatg
     3781 aagcgctact ggaaagtcct gcaccattag ggattgttcc ttccactaat aactcaaacc
     3841 catgatcgat tgagtgtcca gcttctttta atttaaggac cattcctttt acgtaatttg
     3901 cccagtttgc ttttttatca tattctagct catctaaagt aaaactaatg acaccgatat
     3961 cgtcaaagtt tgtggaataa actaatattt tattatcgtc tcgaggtgct gctacacctt
     4021 gcgttccata agtgatggaa gcggggaaga catggcctcc attgtaatct gtgtgttcac
     4081 caatcaaatt gatgcgtcct ggtgagaagt attgtgtagt ttttttaggt ccgaatgttt
     4141 cggcaaattt tgtgtttaag cttcttttga tttccatgat gagttattcc tttcttgttt
     4201 tgattttgaa ttctgtcact gtttcaaata ctgatccggc ttttaaatga atcgaaccaa
     4261 atgctgagaa gcgctctgca cctggagctg tttgagtctc aaatgtgatg ccaccgtgat
     4321 gtgccagttt tcggttgcgc atttctggtg tttctgtgcc gaaatttgca gtgaaaataa
     4381 ccacactaga agcatctgta gcaatatcta cttggattct tttatcgggg ctagtcaagc
     4441 gagcggcttc tttacccaag ccggtttctt ttaagaaaaa tggatgatcg attccgtcaa
     4501 caagattttt ttgatccaaa tcactagcaa aaacggacgc taatttttta ggtatttgaa
     4561 aatcgaaagc acttcctgca gcattttctt ttacccctat aggaatacta tctgttcgca
     4621 aaggagcata agcttcgcta ttgagccaaa gctcatgttg atcgattgac tgagaagcat
     4681 ctcccgtcaa gttgaagtaa acatgatttg tcggattgaa taaagtatct tggtcactgg
     4741 tgccgcgaga ggtcactcgc cagatattat cttttgtcaa agtatagcgg atttccacat
     4801 ccattgtacc tggaaaacca tgttctccgt cgggacttgt agtagtaaaa atgacagaag
     4861 cttcattttc gccattcaaa atgacataag accatttttt taattcaaat ccaggagcac
     4921 caccatgcag attatgtcca gtttttggat ctgtggctaa ttggtaagtt tttccattga
     4981 gagaaaagcg gccattttcg attctccctg cggtgcgacc gatagaagca ccgatatacg
     5041 gatctttttc gatatattct tcagcggtgt caaatcccaa aactaattct cgatcatttg
     5101 attttaaact gacgattcta gcacctaaat cagagataga aagtgctagc ttgtttttgt
     5161 tctccaaggt tatcaagtga taaccttggc caaaatcttt ttctgtaatc ttcattttca
     5221 agatcctttc ttaatgggaa ggaactactg catcgtgaag ttaatcttcc attgtatcag
     5281 ctggagccaa tttgttttcc aatttctcaa cgatttgtgc atgttttttc tctgtcaatg
     5341 taatcttcca agcaaaaata atagcggaga aaatcatcaa agcagcagga gcatagaatg
     5401 cataagcttt gaaagtcgtt acgccatgag cagtgatatc agcagcagta gcattaccag
     5461 tcatcccaga agcgatagcg acaaacccta cgatcccgtt agacaaagca ccagcgattt
     5521 tatctagtaa agggcgaatt gatagagtaa cagcttcgtt acggatacca tttttccatt
     5581 gaccatattc aacagagtct gtgatcgtca tcaaagcgga taagaaaatc aattgttgag
     5641 ggaagtagaa caatactagc ccgatgataa cgattggcaa acttgaacct gcgatcgtaa
     5701 agaaaaagta agaagaaatc atcattgcga tccctccaag gtaaacgtag cgacgagaga
     5761 tgacgcgtgt aagcattggg aatagtggaa cagctactaa accaagtaag gcagcaacta
     5821 gaccaacgat ccaaaattca gttggttggc caagtacata tttgaagaag tagaataata
     5881 cggcagttgt tgctgcattg gcaatcgcat aagcgatata agcaagggca agccacatca
     5941 actgatcatt ttgagcaact gctttgaaca catctttgat cccagctttt tcattttgct
     6001 gacggatcgc agtatcgact tcttttgtgc ccaaggcagt gataatcgca gtaccgcctg
     6061 aaataacagc agcaatcaca ccgaaccaga accagcctga agcgccttca atatgtttat
     6121 gagtaacaag ataggtaaag aaagtaacga tagggacaac gactagagta gtaccatttg
     6181 cacctagaga agagccgaaa cgagcaaacg tagcaaattt ttcacgttcc tttgtttccg
     6241 tactcaaagc tggaatcatt gaccaaaaag cgatatcctt aaatgaataa aaactatcca
     6301 ataagatgaa aacgattgca aataatatga taaataaagt cgtattatga gtagctaagc
     6361 caaagaaatt ggtaaagatt gctaccaaga gtacggaact aacaacgccg ccgataacta
     6421 accatggttt gaatttaccg tattttgtac gagtattatc gatgatgcca ccaatcaaag
     6481 gatcaaaaat aatttcaact aagcggatac ctacaactaa gcttgtaact gtagcaatca
     6541 tttttgcatt cgttgcctta tctgttcctg cgaacatctg gcttgtcacg aataccataa
     6601 aataagtgct taatgtaaca tagaatgtgt cgtgtccaaa agcgcctaaa gcgtaggaca
     6661 cacgttggat cattttgctt ttcataatct gtattcctct cctgttcaat atataatact
     6721 aagtaaaccg gttacaacga ataacaaaga tcttttaatg acttaaactt aacaagaaat
     6781 cgcttccttt ttaatatatt tctgtgactt ttatttaact ttttgttgca ttatactaaa
     6841 ggagtaagga gggatagacg tggagcaatc gattttttta aaaaaggaac atcaacaagt
     6901 agaaaaagaa ttgtattttg atttttgtgg tttctctaaa acgatgccgt ttcattcttt
     6961 tggtcctgct attcgcaatg attacatcct gcatgtcgtg atggaaggca aaggatctta
     7021 tcatgtgaaa aatcaacaat tccaattgaa aaaaggtgat ctgttcttga ttcgtccagg
     7081 agactcgacg ttttacttat cagatggaga agatccgtgg atgtattgct ggctttcatt
     7141 tggtgggagt gctgcagaag aaatcattcg gcagtcgctt ttcagagaag accaatacac
     7201 gatggtctct tctgacatac aaaaatatat cgacattatt ttagaatgca tgaaagatac
     7261 ggaagaaacc ttggaaaatg aattacagtt aacagcatta acctaccgtt ttttatcagt
     7321 ccttttaaaa gatggcggaa aggtcagcgg aggtgtacaa aaggttcatt cctctttagt
     7381 tgttgaaaca gtcaaataca tcgaggcaca ttatgctgaa aaattgtctg ttgaggaaat
     7441 cgcccagcat ttagcggtca atcggagcca tttgtcgcga gtattcaaaa atcatatggg
     7501 caccagtatc aaggaatatt tgatcggggt acggatcaat cgaggggcgt ttcttctttc
     7561 tctgacggat gaatccgtgg aaagtattgc ctatcaagta gggttcaata gtctagtcgt
     7621 atttagccga atgttcaaaa agagtaccgg agaaacggct acgaactatc gtaaacgtat
     7681 gaaaaacgaa aattttaaga atattgcttt ggataccttg aaaaaacagt tggaaaaaca
     7741 aaccgcagtt tcttggacaa cctgattagt ctggttaaaa tgacaagcat cggcaaaaga
     7801 aacttgtggc ggttatgcta cactgtaaag cgaagactaa aaaggaggaa aagggatgcg
     7861 tacacttatc atcattagcc atccaacgat cgaagaatct ttaaatcagc aatttttcaa
     7921 agaagcttct gctggtttac cagctacttg gcatcatttg gaatcaagtt atccagacgg
     7981 aaaaatagat atagagactg aactacagct cttggcccag catgatcgga tcattttcca
     8041 gtttccgttt tactggtata gttctcctgc tcatttaaaa atttggcaag ataatgtctt
     8101 ggaacgagca gcacatgtat taaaagggaa agaactagga atcgtattga caacaggtgt
     8161 ggcggaaaaa gaataccaag ctggaggaaa agaagaatat acgatttccg aatttttgag
     8221 gccgtatcag cgaatcgcaa ataaattcca tatgacctat cttccgccat tcgttttagc
     8281 acaatttatg tatttatccc aggaaaaacg ttgggagaag ctaattgctt atcagcagta
     8341 tctctcattg gaaggcaaac catcgctgac tcagcggatt gactggttta ttcaaagagt
     8401 acaggaaaat cagaaaatgc aggaagaaga atctgaaaaa caagcatata tcgtagaagc
     8461 actgactgag gcaaaagagc agatcgaaga cttgaccttt acactgcaag aaatgaaagg
     8521 aacttcatta tgacaaatga ttggctgatc caacaattag atgaattaag cgaaaaatca
     8581 gaatatcaag accgtgcgct cttatatgaa ataaagaaac tgatggctga gatagacgaa
     8641 cgaacaatgc agctgcaagg agaaatcgac ggacaatctt ggaatcatct caactggtga
     8701 aattttctta taaataacaa agataaaaat gtgcacagcg acaattattt gctacaataa
     8761 gaatatgaag cgtttgataa cgctattata cataaaaatt ggtggtgaaa aaaatgtatg
     8821 atgaaaatga gtggggagaa aatgttcgga tgacccgaag aagacagcaa aaacaggcag
     8881 ctcgtaagcg gatgatcatg attggggcag cagttgccgt gtttttgatc atagcaggag
     8941 gagttgcggg tctatatttt catggaaaaa attcgtcaga agcgaaaagt acgaccataa
     9001 cggaaacaac gacaaagaaa acagagacga aacaaacaag tgagtcatca actaaaacaa
     9061 aagagacaca aacttctgaa gaaaaaacag caaatggttt gccagagcaa cttcaagcaa
     9121 tcgtaaatga ttattcgaaa aagatcgaag aaaagacgcc tgcattgatt gaagaatacc
     9181 agacagaaat tcagggaaat caagagggaa tagctggttt atcagcagtt gctaaccaaa
     9241 aagcacgtga gcttcaagca atctccgacg aagggatcag aaaattacgt gcagcgtatc
     9301 aggcagcaga aaataaagac ggtgtagact tagatacttt gatcaatcaa ttatcggcta
     9361 attatacgaa tcatgtcgct aagatttccg atatttattt gcagactagc gcctctcttc
     9421 aagcagagtc aacaagcaca caagacacaa catcttctga ttctgagaca gcagagtcgg
     9481 tagaagcttc tgaaatgcaa gctcgaacaa cacaagacac aacagattcc tctgaaacta
     9541 ataccaacag cgcgacttca caggctgcga caaccgtagt tttggaagga gaaggtccaa
     9601 atcaaatagc cgaacgaact ggcgtaccag tagaaacgat cttgtcgctg aatgggatga
     9661 gcatggagaa ttatttcctg actcccggtg agacgctaaa attgaattga taaaagcaat
     9721 aaaaaagaac gaagcttcca ctaaggtgaa gcttcgttct ttttttattt tccggttctt
     9781 ttttcgcgta caaagtaatg gatcgtcatg taaagcaaga aaacgagtcc aataatcaat
     9841 gagattctcg tttcaggatt gataaacatg aaaatcaata cgatagctaa aaaagcaagt
     9901 gtcacataat tcgtataagg agatagtggc attttaaaag gatgatcatg cattttatct
     9961 gcgtgcttct ttttgaagcg aatctcgctg atcaaaatca ctacccaagg aaccatacca
    10021 ggcaaaatac ttgagctgta tacgaaaacg aaaatatttt ctgactggtt gatgaacatt
    10081 ggtagaagat aatttaagat cagaccaatt aagattccac ctgagattgc tacgacagga
    10141 taaaaaggcg caccgtgacg agatagtttc agaaattttt tagacatctt tccatttatg
    10201 gcaagtgtat agaccatacg acttgcgctg aaaatccctg aattgcaacc tgataatgcc
    10261 gctgtaatca cgacaaaatt aatcagtcct gcagcaaatg taatgccgac tttagaaaaa
    10321 gtttgtacaa aaggtgaacc aatctcactc aattgattcc acggatagat actcacaatg
    10381 ataaaaatag caccaatata aaaaatcaag attcgaccga tagtggactg gacagcttca
    10441 atgatcgtct ttttaggatt ctctgcttca ccagcagtca ttccgatcag ttcgattcct
    10501 tgataggaag caacaacgat cgataatgca aagaaaaatc ctttgacgcc tccagtgaag
    10561 aatccaccat ttttccaaag atttgaaatc cctactgcct gaccatgatt accaaatcca
    10621 aataagatta ccccaagacc tgcaatgatc atcaaaatga tcgttatgac tttgatgatc
    10681 gaaaaccaaa attctaattc gccaaacgcc ttgacagaaa taagatttgc cagcataaga
    10741 aacaagacga caatgattcc gggaataatt gccggcaaat caggccacca ataattcata
    10801 taagatccta cagcaatcac ttcacttatt cctacgacaa tatattgaaa aatattactc
    10861 caagcggtca agtagccagc cacaggatgg atgtactcgc tcgcgtaatt tgcaaaagaa
    10921 ccagtcgaag gatcaacgta aagcatttcg cctaaagcac gcataatcaa atacaaaaag
    10981 aatcctgcaa tcgcataggc tcccatcact gagggccctg tccaacgtat ggttgaggag
    11041 gcacccataa acagaccgac accgatcgtt ccacctagtg cgatcatttg gatatgacgg
    11101 gcactaagac ttcgagttaa cttttcttct tccatacaaa aactcctttc gttgttgagt
    11161 caacaagaaa aaataatcaa acgtttcaac acatgttttt cattattagg ttagccttat
    11221 tgaactcttg atgtgattct acagaaaatt ttcataaaat gcgaggaaaa ttcgaaaaaa
    11281 actttttcat cattctactt gaaaatgctt tccattttag ttaaactata tttaaataaa
    11341 aagttaggta aacctaaaaa ggagtgtaag atttggaacg tacggccatt gtaattcaag
    11401 acctttcagc cgcttatcaa gggaaaactg ttttgaaaac tatcaacttg acgataaatc
    11461 cacaaaaaat taccggtatt atcggaccaa acggtgcagg aaaatcaaca tttatgaaat
    11521 ctttgctaga gttgatacca gctactactg gtaaagtcac cttttctgga cagccggtaa
    11581 actcagtccg taaaaaaata gcctacgtgg aacagcgaag tgaattggat ctttcctttc
    11641 caattgatgt attaggcgtt gtacttttag gaacatatcc atctttacga attggacaaa
    11701 gacctgggaa aaaagaaaaa gaacgtgcaa gacaagcttt gaaaaaagta gggatggaag
    11761 aatatgccaa aagacagatc agcgaactat cgggtggaca gcttcagaga gtttttattg
    11821 caagagctct agcccaagga gcagaatgga tctttttaga tgaaccattc gtagggattg
    11881 atgcgttaag tgaacgaaag atctttgaca tcttgcagga attgaagaat tcaggaaaaa
    11941 cgattttgat cgtccatcat gatcttcata aagtagaaga atatttcgat gaggttattc
    12001 ttttaaataa acagctgatc gcttccggtc cagtacaaga agtctttaca tcgaagaacc
    12061 ttcaattggc ctatggtgag atcatcagac atttagtaaa aggaggagag aaaaaatgat
    12121 ccaatccttt attgatggat taatgaatta tcaattcctg caatacgctt tggtcacttc
    12181 catgcttgta ggacttgctt ctggagtcat cggttctttt attattttac gagggatgtc
    12241 tttgatggga gacgctatct ctcacgcagt tcttccaggt gtagccattt cttatatgtt
    12301 tggttttagt tacatctttg gagccactgc ttttgggatg ctaacagcag cagtgattgg
    12361 tttcgtgact cagcggagcc gattgaaaaa tgatacagcg attggaattg tctttagctc
    12421 cttttttgca ttagggatta tcttgatttc atatgcccag agtgcgacag atttgtatca
    12481 tattttattt gggaatgtct tagctgttag ggaaagcgat ttgttgctga cagcactcgt
    12541 tagtggaatc gtcttgatat ttgtcttttt cttttataaa gaattgaaga tcacatcatt
    12601 cgatccgaca atggcaaaag cttatgggct gaacacatcg ctgatccatt atcttttgat
    12661 gttctttttg acattagtgg ctgtagtcag tttacagaca gtaggaacaa tcttggtgat
    12721 tgccatgttg atcacaccag ccgccacggc ttacttgcta acgaaccatt tactgaaaat
    12781 gatcattaca gctgcaggaa tcggtatgct aagtgcagtt gtcggtgtgt ttttcagtta
    12841 tagttacaat tggccatcag gagctacgat cgtgttagca tgtaccgcat tttttatcct
    12901 tgctttttta ttttctccaa caaaaggaat tttatttcag aaaggaagca gatagatgaa
    12961 aacaaaaaaa tcactctttt taatcttggc agttagtttc ttggtattag ccggttgcgg
    13021 aaagcaggct tctgaccaag cggatgaagg aagtaaagaa aagttgtcag tcgtggctac
    13081 caattcgatc ttggcggaca tggcaaaaga ggtcggaaca gatcaaatag atatccacag
    13141 tatcgtacca gtcggaacag atccgcatga atatgaagta ctaccagaag acatcaaaaa
    13201 ggcaagcgat gcagatgtta ttttatacaa cggtttgaat cttgaaacag gtaacagctg
    13261 gttcgataac ttgatggaaa cggctaaaaa agaagaagga aaagattatt ttgcagttag
    13321 caaaaatgta gaacctcttt atttaactag cggtgaagaa catacaaaag cagatcccca
    13381 tgcttggcta gacctatcta acggaataaa atatgtggag gaaatcgcac gtatattctc
    13441 tgaaaaagat gcagaaaatg cgacactcta taaaaaaaat gcagaagcat atgtggaaaa
    13501 actaaaagaa ttagatacac aagcgaagga aagttttgct tctatcgaag agaacaaaaa
    13561 attattagta acaagtgaag gggcattcaa gtatttttca cgagcatatg atttgccagc
    13621 agcttatata tgggagatca atacagaaag tcaaggtacg cctgatcaaa tgaaagcgat
    13681 cattgatcag ataagagcaa aagaagtacc ggttttattc gtggaaacca gtgtagactc
    13741 aagaagcatg gaacgggtag caaaagaaac gggtttgaaa atctatgata aactgttcac
    13801 tgattccata gcaaaagaag gagaacaagg agattcttac tatcagatga tgaaatggaa
    13861 tattgaaacg atccatgaag gtttgtcaca aacaaaagaa agctgaaaag tgcaaggtct
    13921 agcttgagga gcagaccttg cattttttat aagagatatg aaaaaaaatt atgctgtttt
    13981 tcgtcgtaca gatacctttt ttgaagaaat tccgttatag ttagagtaag gaaggaaggt
    14041 gtggctatga attttacacg taaagataaa tatacgatta aagaagaagt ctttcgattg
    14101 atcagccagc aggaaaatac cgacaaggat caagaccttc aatttcttga agcagaatta
    14161 gctaaattat tcatagcaaa tcaaaatgag acaacagaac cagatgaaga gctgtacata
    14221 ggcaaatggt tgtttgatga atttcagcct ttagatgaaa ataccggtat cggttatttt
    14281 gtgttccttt ctccagtcgg cttcacacct ggcgtattag ttaaacaaaa cgacgaaata
    14341 accgtcaaag catggcctgc attattttca gtcatcaaag cagaaggagt aatcaaaaag
    14401 atccagtcgg cctattataa aagtcaattt attgccaaca gcaaattaat gaatatgttt
    14461 tataatcgtc tagtagaaat tgctaggcct gggaaaatcc cgcaaacatt cacgtacaca
    14521 cagcaaaaaa atctctatga agaagtattg tattcccgcg atctgtctga gttttcgcca
    14581 tgggaagagg taaggctcca tgaactgtta agtacaaaac cagtttcatt gaattttttt
    14641 aatgcattag ataacaaaag aaaattaatt tcaacaaatt attgggaagt atttgctgca
    14701 agaaaaaaat ggatggaaga aaagaagatt gccgatcagc agatccagtt tgtccagctg
    14761 aaaaaagaaa aactatatta tgggttatac agccgttaac agcaagcgag gaagaccatg
    14821 acattaaaag aagaaatcat acaagaaagc aaacgattag gaattgacaa aatcgggttc
    14881 accacggcgg aaccttttga ttcattaaaa gaatcgttgg aagaacaaaa agcagctggc
    14941 catacttctg gctttgaaca tccaaatatc gatgagcgtc tttatccaga aatgacattt
    15001 gatcagccga aatcgatcat ttccattgca cttgcgtatc ctactaggat ccatgaagaa
    15061 gtgcctaggg atgaaaaacg cgggcagttt gctcgtgctt cttgggggat cgattaccat
    15121 gatatactca gagaccgttt gaaccgattg atcgaattca tccaaacaag agcagaaaaa
    15181 tggcaaaaag aagaggaatg gcgtctagct ccgcaagtag atactggaga actgatcgat
    15241 gtcgctgtag cacagcgagc tggtttagga tttattggac gaaacggatt gttgatcact
    15301 gaagagttcg gttcatttgt ctatcttggt gagatcgtta ctaatattgt atttgagcct
    15361 gataaaccag gagaatttgg ttgcggtgac tgtatgcgct gcgtgactgc ttgtccgaca
    15421 aaagcattgc ttggtgacgg aagaatgaat gcccagcgat gtttgtctta tcaaactcag
    15481 acaaaaggga tgatgccgga agaatatcgt aaaaaaatgc gaaatgtcat ttatggatgt
    15541 gatatctgcc agttagtctg cccttacaat caaggaaaag attttcattt tcatgaagag
    15601 atggaaccaa aagtagacga aatatatcca aaattaaagc caatgctttc gatgtctaat
    15661 aaagacttca aacagcaatt tgggcattta gctggttcat ggcgtgggaa gaaacctttg
    15721 cagagaaacg cattgattgc tttagctaat ctaggtgatc gaacggcatt gcctgagatt
    15781 tcagaatgtt taacagatgt ccgccctgtc atcagaggaa cagcagcttg ggctattgga
    15841 cgtctaggaa caaaagaacc ggaaaaatgg cttgatgtat tagatgaaat attagctaaa
    15901 gaaacagaag aagtcgttat aaacgaattg gaacatgccc agaaattatt gcggagaaag
    15961 ttaaaataaa aaaatagtta acattattca aagtttttgt ccagtaattg ttgtaacaat
    16021 tactggtttt tttgtatttt ttacattttt ttaagagaat ttgataaaaa tcaaaaattt
    16081 ttttgctttt ttttatggat tattgcagtg aatgttacag aatctgcgtt tttcattcaa
    16141 aaataaaaaa acatagaaaa acgattactt tgcttataca acaaggcttt tatggttttg
    16201 tatcaaaaaa at
//
LOCUS       DAXQKX010000057        16183 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.058, whole genome shotgun sequence.
ACCESSION   DAXQKX010000057 DAXQKX010000000
VERSION     DAXQKX010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16183)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16183)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16183
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.058"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(200..598)
                     /locus_tag="ACF3MF_002114"
     CDS             complement(200..598)
                     /locus_tag="ACF3MF_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030234 - enzyme regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006808 - regulation of nitrogen
                     utilization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HFE3928074.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(595..1368)
                     /locus_tag="ACF3MF_002115"
     CDS             complement(595..1368)
                     /locus_tag="ACF3MF_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HFE3928075.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(1365..2048)
                     /locus_tag="ACF3MF_002116"
     CDS             complement(1365..2048)
                     /locus_tag="ACF3MF_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HFE3928076.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(2215..3102)
                     /locus_tag="ACF3MF_002117"
     CDS             complement(2215..3102)
                     /locus_tag="ACF3MF_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFE3928077.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(3099..3968)
                     /locus_tag="ACF3MF_002118"
     CDS             complement(3099..3968)
                     /locus_tag="ACF3MF_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFE3928078.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(4105..5391)
                     /locus_tag="ACF3MF_002119"
     CDS             complement(4105..5391)
                     /locus_tag="ACF3MF_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFE3928079.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            5664..6242
                     /locus_tag="ACF3MF_002120"
     CDS             5664..6242
                     /locus_tag="ACF3MF_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFE3928080.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            6242..7171
                     /locus_tag="ACF3MF_002121"
     CDS             6242..7171
                     /locus_tag="ACF3MF_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3928081.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            7168..8904
                     /locus_tag="ACF3MF_002122"
     CDS             7168..8904
                     /locus_tag="ACF3MF_002122"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFE3928082.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(8967..9803)
                     /gene="pheA"
                     /locus_tag="ACF3MF_002123"
     CDS             complement(8967..9803)
                     /gene="pheA"
                     /locus_tag="ACF3MF_002123"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HFE3928083.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(9800..10309)
                     /locus_tag="ACF3MF_002124"
     CDS             complement(9800..10309)
                     /locus_tag="ACF3MF_002124"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HFE3928084.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(10302..11597)
                     /gene="aroA"
                     /locus_tag="ACF3MF_002125"
     CDS             complement(10302..11597)
                     /gene="aroA"
                     /locus_tag="ACF3MF_002125"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HFE3928085.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(11610..12701)
                     /locus_tag="ACF3MF_002126"
     CDS             complement(11610..12701)
                     /locus_tag="ACF3MF_002126"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HFE3928086.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(12718..13884)
                     /gene="aroC"
                     /locus_tag="ACF3MF_002127"
     CDS             complement(12718..13884)
                     /gene="aroC"
                     /locus_tag="ACF3MF_002127"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HFE3928087.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(13886..14950)
                     /gene="aroB"
                     /locus_tag="ACF3MF_002128"
     CDS             complement(13886..14950)
                     /gene="aroB"
                     /locus_tag="ACF3MF_002128"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HFE3928088.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(14983..16005)
                     /gene="aroF"
                     /locus_tag="ACF3MF_002129"
     CDS             complement(14983..16005)
                     /gene="aroF"
                     /locus_tag="ACF3MF_002129"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HFE3928089.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
BASE COUNT         4655 a         3585 c         2875 g         5068 t
ORIGIN      
        1 aactaaaaaa ttcatttttc tccccctttt ttcatcattt ttaaaatagc atattttgaa
       61 aagaaagtct gatgcttaga gtagaatttc ataaaaattt actatttcat aagtattcac
      121 gagaaaaata caaacaaaaa agcggaaata acgctcatcc gccttcttgt ttgtgtttat
      181 ttcctcttca aacgcttgtc tatgattcag acttttctct atcgttattt tcatctaaaa
      241 gttcttgcat tccgataatt tctcgatatt gatgaatctt agtgatacca atgactttgt
      301 ctacatcaat actaaaacaa ataccattac ctggaatatc gatgttgatg ccttgaccaa
      361 tcgcatccat tactttattc gtcaaactat cgggtactaa tgtcaacaca atatcttttt
      421 ctggcgaaat gtccaaacct aaaaatttcc ctgaatcatg tacaccagaa cctcttccat
      481 gtaagatcgt tccgcctgct gcacctgctt cttttgaaaa gtcgataaca tcttcgccca
      541 ttcctccgtc aacgatcgtc acaatcatgt gaagattcaa tgctacaaga tctttcattt
      601 gctttccccc aatttttgca atctttcttt ttcgattctg tctttttcat cttttcgttt
      661 ataaatatat cctagtacta aagtggataa tattggtgtc aatgcaatca ttgcaaccac
      721 accaaacccg tcaatgatcg gatctcttcc ttcaatttgt gcagcgattg ccacgctcat
      781 tgataaaata aatgtcgaac acatcgggcc cgttgctact ccaccgttat caaaagccat
      841 tgctaaaaag atcttgtcca cttttcgtcc taaaataaat gctagcccgt atcctgggat
      901 caagaaataa taaagagaga atccgacgag caaacgccac atagacaatc ctactgctgc
      961 gccgatccca attgaaatta ccatcagcat gattttcgat cggattctcc cctcgctcaa
     1021 ttcttcaacc tgtttgatca ttacatgaat cgccggctca gcaaacccta ctaagaaccc
     1081 cattaaaaag ccaaggggaa ccagtatata attgtaaggc aatcccgcaa tagcactgcc
     1141 taaatgctgt cctaccggta cataagccat attgactccg tgcaggaaaa ggatcaaccc
     1201 aatagtcgtt atcaagaaac ctttcataat gtcaaagaaa cgctttttgc gcatacgaaa
     1261 actaatgata ttcattaaaa caaataggat tacgataggt gccactgcca aaatgacttc
     1321 catggtaacg atttcgattc catctatcac ttgctgccag aaactcattg gaagatcacc
     1381 cccaaaatca tcacggcaag aatcggccct aacgaagcaa taccgaccat tccaaaactg
     1441 tcattttcat ttttcttttg tttgatcata ctagtcatcc ctccggcaag ggccaagata
     1501 aatggaacag ttactggacc agtagtcact ccccccgaat caaaagcaat cggcataaat
     1561 tcggaactgg tgaaaaatga ggcgatcaaa acgcctatgt agcctatagc catcaattga
     1621 taataggata gcttgaatac gacccgaagc agcgcaaagg ctagaaatac tccagtgccg
     1681 acgctgacga tcccaatcag caacactctg ccaatctctc cgtcagatat atcatatact
     1741 tgttgtccca aaacttgcac ggaaggttca gcaatcgtga tcacgatccc gatagcaaat
     1801 cccaaactga ccaaaacggt caaacttttc tttttgatca tatatttccc tactagatct
     1861 ccgacttcca tcatagaata atctgctcca aacaaaaaga gcgtcattcc gatcatcatg
     1921 attgccgcac caaccagaaa tgaagcgagg tcttctcctt ctaacggtgc aaaaacaaac
     1981 gttaaaatga caatcaggac agtcatcggc aatatagcag caatcacttc tttaaaattt
     2041 tttagcatgt atcctcctcc tttactcttt aagtttacct taaaatgaaa gagttttcga
     2101 gcacaaactt aaaacgttat catttaattt ttctcaacat aaaataacac acgtcccaaa
     2161 agtatctttt tacttggaaa aatgactttg aaggaacgcg cttattgtgt ttttttattt
     2221 tacagagccg atcattcctt gaacgaattg cttttgcaaa acaaaaaata cgatggcagt
     2281 tggtaaagta gcgatgacta atccagccat gatcattcca tagtctggtg tataggaagc
     2341 acccatagca gataaaacaa gcggaaccgt ccgtttatca ggagattgca aagctactaa
     2401 gggccataaa taattgttcc agctactcat gaatgtgatg attgcagccg cggcataggt
     2461 atttttagcc gtcggcatat acactctaaa aaaaatactt agttctttta gaccgtctaa
     2521 tcgagcggct tctactagat cttttggaaa agatttaaca ttttgtcgaa agaagaagat
     2581 caaaaaagca gtgctaacag atggcaggat gacaaccaag aaactgttga ttcccaaaac
     2641 cgttccgttc aattgtgaaa acattcgata taaagggatc atcaatgccg caaaaggaac
     2701 catcatcgat agcagtagaa tattgaaaat taggtctttt cgtttacttt gataaatctc
     2761 aaatccatat cctgccattg acgaaatcag caatgcaaac acagtggtca ccaaagcgat
     2821 catcgctgaa ttccaaaggg aacgagtaaa attcagctca ttggaaaaca aattttgaaa
     2881 attgatgatc aagttactgc caatctttat ttttcccgat gtgatatcca cgggtgtatt
     2941 cgtcattccc aaaaccatcc agacaaaagg gaaaatggaa ataaatgata ggatgcttaa
     3001 tgctgtatac tttaatactg acccaattgt cgaacgaagt tctaatgctt gttttttgac
     3061 gttggggcgt tcgattgttt ctttttctac catatttttc atcgactttc tcctcctact
     3121 ttcgtttgga ttatcgacaa tatcacaata aaggaaacaa taacaaagga aactgctgcc
     3181 gcatatccaa aattaggcgt gaatttataa ctcaaattat agatgtattg agatagggtg
     3241 gtcgttgcat ttgctggtcc cccgccagta atattttgta cttcatcaaa aagctgcaat
     3301 gtcccgatcg tcgaagtaat ggaagtaaac aaaatgattg gttttaaatt tgggatcgtc
     3361 actttgataa actgctgcca tttagaagca ccgtcaatag atgctgcttc ataaatctcc
     3421 gaatcaatat tttgcatgcc tgaaaggaaa aaaatcatat tgtatccagt ccaacgccaa
     3481 gtgatcgaaa gaatgatcag aactctcgcc caaattggat gagtcaacca gccaatcggt
     3541 gtgtcaatca taccaatgcc caacaacaag ttgtttacaa ggccagattg agaaaataga
     3601 cttttcatga tcagagaata actgaccatc gaagtgatac atggaagaaa gatagcggtt
     3661 cgaaacaacc ctttatattt caacttttta tcatttaaaa ggttggaaat aaaaagtgct
     3721 agaaacaaca tgatcggtac ttgtacaagt aaatacagga atgtattaaa aaaagctttt
     3781 ttaaaagttg catctgtcaa catccgctga taattaccta acccgttaaa tgtcatattg
     3841 acagggggac cactttgaaa agacgtgatc aaagccaaaa ccatcggaat aaaaaccatg
     3901 attgatatca aaatgactgg caagattaaa aaagcatgcc cgtttttgaa taaatctttc
     3961 tgcttcattc ttttccctcc aattctatca ttgattatct acatgaaaag acaagaaaga
     4021 caatatctgt aaggcagacg tgatcttttt tgtcttttcg tttgtctgat gaaaaagcga
     4081 agaaattcac ttttttacca ccgatcaatt agccaattgt gcttctactt gtttttgtgt
     4141 atctgctagt accttgtctg tctcttctcc attgatgatt cgatgaagag cttcagctac
     4201 gactgcttca attgcatagg tctcatgtcc gtaattcact tctggtattt cagatgtcca
     4261 tgttgaaaaa tcgtcaaaga tcttttgacc actgtaaaat tcagaagctt cttgataagc
     4321 ttcttgttca ttcgcgctaa gcatcgtaga tactagtccg atttctttcg caagagtgcc
     4381 catcagttct tcattcgaag caaacgttgc ttctaggaaa tctttcgctg aatcttctcc
     4441 agctactcct ttgatcacat accagccagc gccgccaagg ttagaagctt gcgctttttg
     4501 cagattttct ggaagtgcag gtattggtgc aatcttccat tttccagatt ggttttctgc
     4561 tccttggatc gttgaagaat accaagcgcc agttgggcta gaagctactg ctcctgattg
     4621 tatcgcagtt actccagcat tccagtcaga ggtttgttcg actagatctt ctttcaaaag
     4681 agtggcaaac aattcaagac catactttaa agatgcattg tcttggatcg tgactgtctc
     4741 cccatcttca gatgtatacc attctcctgc ctgttgcata atcatcctta ctcgaccaag
     4801 gtcagaagga ttgacttcag cgattttctt tcccgtcttt tctttgacat ctcgcgctac
     4861 ttgaatatac tcgtcccact tcagattctc catatcctct tctgtataac ctgcttctgc
     4921 catcagatcc gtacgataga agtttgctgt tacgcccgaa tcgaaaggaa caccgtatat
     4981 tttatctcct actttgttta ccgcaaattt atacggtgca aaatgatctt cctttacaat
     5041 agcagacaaa ttagcgaatg catctggata agaagtcaaa tagccttgta tcctataatc
     5101 ttcaatcaag acgatattgg gcaatccttc tgtattcccg ctcgctaaag cggtgttcag
     5161 tttctgaacg atatcatcct gagacatcgt aacaacttct atctctgttt cttcgttctc
     5221 ataaactttt tttgcttcat tcactgcttt gatattgaat gtctcatccc acgcccagac
     5281 agtgactttt tcttctttgt ctgctgtact actagcactt ccgcatcctg ttaagaaacc
     5341 tgatgctgcc gctaaacaaa cgactccagc aattaacttt ctgatgttca tttttatccg
     5401 ctccttttcc atccattagt tgtttacgtt tgctacattc atcataccaa aatttgaaaa
     5461 cggtttcttt attattcaga tacttcaaaa atttctccta aaataataaa aaaatacaaa
     5521 tcaactatga caaaaggaat aatcttagca tctagaccaa agatcgaaat ggtgaggttt
     5581 ctttaaaata aaaatatcct tgcattttct cctagaaata agtattttta aattacaaga
     5641 ctattcttaa ggcgggtaaa aaaatgccaa tacgcgtaat tcttatcgat gatgaacaga
     5701 cgattttaga tggaatgaaa cagttgatca attggtctga gcacgggttt caattaatag
     5761 ggactttttc cagtccgctg aaagcgcttg atttttcttt ggtacatgca atcgatatcg
     5821 tggtcacaga tgtaatgatg cctgaattaa atggaatcga attatcgcgg ctattaaaac
     5881 agcaacaacc tgaaacacag atccttatcc tctctagcta tgatgaattt gatatggtta
     5941 aagattcttt taaagaaggc gtcgctgatt atcttttaaa gcctcgattg agtcctgatt
     6001 tttttctaaa ttccttaact gccgtttcac aaaaaatcaa aaaaaagccc aacaaaagcc
     6061 caatcaccaa tcgttatgag cagatctgcg agaatctttc acagcagatt gctggacaaa
     6121 ctcgtccatt gcttgaccct cttctttttg aacacacctt gtttttctgt tatataccga
     6181 aaaacggcca ttcagttcaa aacaaggctc taaacaaaaa cagtcgatca cccattcatt
     6241 gatggatagc gacgattcgt ttactattta tcctgtttct accttttcgg aagaatccgg
     6301 ctatgtaatc aatactgatt ccaaagatac acttaggaag tttgttcaaa agtttcgtca
     6361 agaagttttt ccaggtgatt tttttgttgt ttctgattct tttgcaatcc aagatatcaa
     6421 tgaaatattc caagagatca gaaattgcac caaaggacaa cgtttctatc ataagggaaa
     6481 gaaccttgct tatcagcatg aacttcttcc gttattaacc aaccacgagc agcaagcaag
     6541 tagttattta acaaaaatcg ttcataaaga ctacgcttta gctgtcaaag aacttgagaa
     6601 tttcttcacg acgatattgg aacagcctat tgatccagct tatttgaaac atgaggcaat
     6661 caatcgtttc tatgcattac tcaacgcttt ggctgacgag catgttggga atgaagaact
     6721 ttctttgctc aagatcgccc ttccttcttt attagccgat gctgagtatt tcgaagattt
     6781 ttctattctt gtcaaagaaa cacttgagaa actcacccac ttttctgcaa atgcaaaaaa
     6841 agacaatttc gatatcttga ctttgatcta cgagttcgtc caggaaaatt atgagaaaga
     6901 aatcaattta caacttttat ccgaaaaata tcatttttca tatagctatc tctcagccat
     6961 ctttactgaa aaatttggta tcaacttttc aaaatatcta aaaaaagtcc gtatcagtaa
     7021 agccaagctc tttttgacgg aaacacggct tactttgacg gaaatctgtg agaaagtcgg
     7081 ctataccgaa ctgggttatt tctccagagt ttttaaagaa gagacaggaa tgacaccttc
     7141 tcaataccgt aaaggaactt ttgtaaaatg agaaaaaaaa tcaaagagca tgaactcttt
     7201 gccaaacttc tgttcatttt gttcatcggt ctttttctgc aagccatcgt catttctttg
     7261 tttatttatc atcgatcaag ggatgcctat atccagctgt tcaatcaatc gaatgatgtg
     7321 gtactaaaaa agattcaatc tgaatttgaa agtttgaatg atacaatcga gaatacatta
     7381 gccgcttttg attctaatcc agctgtcaaa agctattttt ccaatgatcc agcccaacat
     7441 atggaacagc ttcagcaact aagaacaatc caaaaaatga atgactctct ttcaaaaatc
     7501 catccaatga tcgattacga tgtattgatc tttggagaaa atggaagaac ttttgtcgga
     7561 aacgacatgc tcactgccgt atctgccgat tctttttttc aatctgcgat tgctcagaga
     7621 gtgaatgaac gtgctgctga tacacaaatg ctttttgcac accacggatt gactcttcgc
     7681 gataagaaag cacccagcgt cttctttgtc aaaaaactga aaaatacatt gaatcacgtt
     7741 tacggatatg ctgttttatc gatctcatcc aagcaactag cgaatctttt tcaatctgta
     7801 gtaaatcctg agatatcgaa gatctccttc atgaacgaag aacagacgat catcgcatca
     7861 aatgaagaaa atacaattgg gagccgatca atgattttca aaaaactaac agtaggtgaa
     7921 acaacgattt caaatggaca gcagttgacc cgtcttcctc tgtaccgcca ggattgtaca
     7981 ttactcagtc aagtcgatct tcattcttta tctaaccaaa tgggcgtgat ttttccgatt
     8041 attttgtata atatcgtgac acttgctttt gctggctcat tggtatttat gtatttggat
     8101 cgacacacaa aatcgatcta ccgcttgatt gattcgctaa aacggctaga ggaagatggc
     8161 ttaaaagcta ctgttcctgt acaaggaagc catgaagtcc aattgctagg gaatacgatc
     8221 aatcaattgc taagtaatgc tcagcatcat tatgaacaga cgatccaaga cgaaaagaag
     8281 aaacgttcgc ttgaaatcca aactatgcaa gcacagatac agccccattt tatttataat
     8341 acgctgacta gcttgaaatt tttgatttgg cagaaaaaaa cagatgaagc agttcaagga
     8401 atcgacagtt tcattacttt actaagaagt acgattggga aaaaagaaga agtgattcca
     8461 gtcaaggaag aaatcaaaag cgtacaaagt tacatcgatc ttttgagtat gcgatatggc
     8521 gaaagaatct cggctaaaat aatgattcct gatgaactgc agtcattatc tatgccgaat
     8581 atgatccttc aaccaattat cgaaaacgcc tatcttcatg cttttcacaa taaaacgcaa
     8641 ggattcatca cggtgtacgg caaaacaaaa aatcagcttc ttttattcga agtgattgat
     8701 aacggcgatg gcttcgatac tgaaaatacc aaacaaaaaa atgatcattt ttcaggaatc
     8761 ggcatcagcc atgtagatga gcggatacgc ctaatgtatg gcgatgcata tggcttaacg
     8821 atccaatcag tgattgggac aggaacgact gtaacgattt gtctaccgct tcttcctaaa
     8881 aatcaatcag aatatcaaaa ataaagaata gccaagcgct gattttttta ttttaagtta
     8941 aataaatcaa tcagtattct tgactttcat ctacgcgtct cttctactgt cagcactgga
     9001 taacagccca atatttgact ttctcctccg agcatcttga tttcttggag cgcattctct
     9061 actaatgtca ttggacggtc caacaacaaa tcgatcacga aaaaatattc tcccaagcta
     9121 gttttcaatg gtcgggattc aatcttactt aagttgattt cccgccagcc aaaagctgcc
     9181 agcattttat gaagcatccc tggccgatta gcaggtagtg tcaagatgac actcattttt
     9241 actggagctg actgctggct ggtcatcttt cggtcaccga cgatccaaaa acgtgtctgg
     9301 ttcaactcat tatcttggat attctcagct aagatctcca atccaacatg ctgtgctgtt
     9361 tctaatgaag caatcgctgc tgcgtcttct ttcggatgtt ctgctacata cattgctgca
     9421 gcagttgttg attctgttgc tactaaagga acattaggat aatgcgtttc taaaaactgt
     9481 tgtgattgtg ctagtgcttg tggatgtgaa aggatttttg taatctttgt tgctggattg
     9541 cctaaaagct gctgcttgat aggaagaacg atttcacttt taacttcgac ttctggatgt
     9601 ttggaaagaa gatcgattgt gtgatgaaca gctccttcca atgaattctc tacaggaacg
     9661 acagccagat cgacttgttt gcgaaacaaa gcgcgcaaac aaacagggat ggaagcatac
     9721 gcagtcaatt gttctgtagg aaatagctga caagccgcct gataagtgaa tgaactttct
     9781 ggccctagat agctgacgtt catatgcttt tgatcctttc tataatggta tcgatgatct
     9841 tttctggtgt ttgattggtc gtgttgattc gatgtgtcgc actttcttca taccaagaaa
     9901 gtcgttgtgc caataatgct tttatttctt ctcttgtttt tccaagagct aaaggtcgaa
     9961 tagacgtttc atcttgttgg atacgatcaa ctagacagtc cgcttctgcc tctaagtaaa
    10021 gaacaatcgg ctgtgttttt aaaaaacgcc gattttctgc actttggaca atccctccac
    10081 cagtcgcgat aattttgtct tcatttgaca gctttcttaa aatatctgac tccacttttc
    10141 gaaagctttt ttcaccgtaa tagtgaaaat attcggcaat cgacaattgg atatgttcct
    10201 caatctttgt atctaaatct acatactctt tttgtaaaca ttgagctaac cctttaccga
    10261 ttgttgtttt tccagcgccc atgaaaccaa tcagcaaaat gctagccatg agcttctcct
    10321 cctgacacaa gttctgctaa atcgtcaaaa aatgccggat aagagattga aacagcttca
    10381 gctccttcta gttcgcaagg tccatcagct atcaaagcag ctacttgcag catcataccg
    10441 attcgatgat cgcctctgct ggacactttt gcgccatgca gaggtgtcgg cccatggatg
    10501 atcagaccgt ctgctgtcgc ttttatcttt gctcccattt tctgtaattc ttctgccacc
    10561 gcatcaattc tgttggtttc ttttactttt aattcttctg cgtctttgat gatcgtgatt
    10621 ccttctgctt gagtagccac taaagctaga atgggcaatt catcaatcag acgcggaatg
    10681 atttctccac caatcgttgc tttcttcaaa tgactcgtct tgacacttaa atcagccgat
    10741 tggttctgtt cattgtgatt cgtctgggta atcgctgcgc ccatctcctc caacacatct
    10801 aagataccag ttcttgttgg attgaccccg acatttttta acaacagttg gctttccgga
    10861 acaagaagtc ctgctgctag aaagaaagca gctgatgaaa tatcacctgg aacagttatc
    10921 tgttgaccag ttaatttttg cggtccggtc actatgatcg ttttatcttc cactgtgatc
    10981 cttccgccaa attgacgaat catttcttcc gtatggttac gggaacgttc tttttcaacg
    11041 attacggatg tgccttctgc ttgtaatgcc gcaaacagca aagcagattt gacttgcgca
    11101 ctggctacag gcatattgta tcggataggt gataaagagc gggttcctgt cacagtgatt
    11161 ggtagatact ggtcattttc ttctccttgc aagtcagcgc ccatctcgcg taaaggttcc
    11221 atcactcgcc ccattggacg tttagacaac gaagcatccc cgaacagagt agtcgtaaaa
    11281 ggctgtccag ccaaaatacc catcaataaa cgtatggtcg taccggagtt tcccatgtca
    11341 attgattcgg ttggttggac aaatgagtgg ctaccgcgac catgaatctt gatcacctct
    11401 tcctcttctt cgatctcgac acctaattgt tggaaggcat gtaaagtact cagacaatct
    11461 tctgcgcgca aaaaattttg tatagtcgtc gttccttcag caattgctcc aaacatgatg
    11521 ctgcgatggg aaattgattt atctgctggt atcctaacag tccctcttaa tccatgtatt
    11581 tgttgtaata attgcattta tccagcctcc tatttgatcc agcaatgata actggtatta
    11641 gacataatga ttctttttgc ttgtaacaaa tcctgttggt ttttaaaact gatttgcagt
    11701 attcctaaaa tatcttccct ggtctcttgg atcttcaaat taatcaaaga aactcccgct
    11761 tttccgatca gtccagttac ttctgcaata acgccaggtt catctggcac atcgataaat
    11821 aaatcaaaaa aggcaggaat cgcgccttgc ttatggacag gcaactggtc tcgactttct
    11881 tttgcccgat tgaaaaaaga aaagatttcc gattggttct cagtcatgat ccattctgct
    11941 atttgtgtca tttcttgttg ccaatctgcc aatcgttcca ataatatctg cttattgctc
    12001 aacaaaatat ctgtccacat gacaggatct gaggaagcga tcctagtgat atctcgaaag
    12061 cctcctgctg ccagttgttt ggctcgcgga tactcttgat tgaattgttc tgcctgattg
    12121 actaagccag ctgccagaat atgtggaaaa tgacttagca ttcctgttat acggtcatgt
    12181 tctcttgctg taagagttac atattttgct ttggttccgc aaaatagttc ttgcagtttt
    12241 tcaacatctt ttttcgtctt ttccaaaggt gtaaagatgt aataggcatt ttcaaatagt
    12301 ttagcatctg ctgcctgtat acctgattta tgagaaccag ccattggatg tccaccgaca
    12361 aaccgaagat ttttctgctc agcggatgtc acgacttgct gcttcgtact gctgacatcc
    12421 gtaatgatga cgtgatcaga caagttgatt ctttcaagga catcaagata agctaaggtt
    12481 gtacggacgg gaacggctaa taagataacg tctgcttgtt ctgcacctgt ttcaaaatca
    12541 cttgcaacgt aatcaacgat ctgctgttct actgcttgct cacgggtttt tgactgacta
    12601 tcccaaccaa ctactatcag ttctggattg gtctgacgaa tacaaagtgc catagaagca
    12661 ccaatcagtc caagccccac gataaaaaca tgttgtgcca tcttatttgc ccccttttta
    12721 gtaatgtttc aagtagtcac ggtactcctt cactgcagct ttcaactcaa caagcgaatc
    12781 acttgggaat tttgacaata gctctgtcgc taccacagtg gctacaacat tttccgcaac
    12841 gacgctagct gcaggaactg ctgtactatc cgaacgttct acacttgctt tgtaaggttc
    12901 ttttgtatcg atatcaacac tttgaagtgg cttgtacaat gtaggaatgg gtttcatgac
    12961 cccgcgaatg acaagtggtt cgccattggt cattccgcct tcgaagccgc ctagattatt
    13021 ggtacgtcgg aaatagcctc tttcttcttc ccataggatc tcatccatca cttctgagcc
    13081 tggtaatgaa ccagaagtga atccgacccc aaattctacg cctttaaagg cattgatact
    13141 aaccacagct tgtgcgattt tggcatctag cttcgtgtcc cattgtacgt agcttcctaa
    13201 tccagctgga acgcctccaa cgagcacttc tacaattcct ccgatcgtat ctccattttt
    13261 ctttgtctga tcgatcaaat cttttattct ttgctcaact gctggatcaa caactcgtac
    13321 ttctgacgct tcagaaattt ctttgatttc ttgaatcgag atatttccag gtatttctgc
    13381 ttggattcca ccaagacaaa tcacgtgtcc tgctacgatg atgtcaagtt cttccagaat
    13441 tttcttggca attgcgccga ttgctacacg catggtcgtc tctcttgcag aggaccgttc
    13501 aagcacattc cgaagatctc gatgatggta tttcataccg cctaccaaat ccgcgtgtcc
    13561 tggacgcgga cgtgcaactc gccgcagtga ttggtctttt tcaggcactt ctgctacaga
    13621 catgacagtt gtccaatttt tccaatcttt attttctacc actaaagtga caggtgaacc
    13681 aattgttttg ccgtgacgga tgccagacgt gatccgaaca cgatcttttt cgatcttcat
    13741 ccttcctcct ctgccgtaac cagcttgtct gcgagcgagt tcgtgattga tttcttcttc
    13801 tgacagaggt aatcctgctg gtagtccttc aataatggct gttaattctg gtccatggga
    13861 ttctcccgca gtcatataac gcatcttaca gtcctcctaa gtaatctttg aatgtctctg
    13921 tgggaacagg aacgattttt gcttgcccaa tcttttctag caagatgata ttcaattggc
    13981 ttcctcttgc tttcttatca tgggttatcg cgtggaataa ttcatctgga tgacttagat
    14041 cgtacgtaat cggcagatgg aatttttgaa gtatcctttc taaagcagct gtcgatccag
    14101 ttggagacaa gccgattttt tctgcatgag aagtgatggc taccattcca atagctactc
    14161 cttctccatg actgactacc ccatatcctg ctgtattttc aattgcatgg ccaattgtat
    14221 gaccaaaatt taaaataagt cgatttcctt ggtcaaagac atcttcttcc actacttttc
    14281 gtttgatttc caacgtagca gtaatgattg gaacagcatg ttccagaaga tctttttcgt
    14341 ctttcagctc gttcagctgt ttccaaagcg ttgcatctgc tatagctgct gatttgatga
    14401 tttcagcgat tccttctcgt aaacgacgta ccggcaaagt ttttagaacc tcaggatcaa
    14461 tcaatacacc agctggctgg ctaaatgttc cgacaaggtt tttcgctttg tttgtattga
    14521 ctgctgtctt cccgccaata ctagaatcta cttgtgcaag tagcgtagtc ggaatttgaa
    14581 cgaaatggat cccacgcatg aacgtcgagg ccacgaatgc tgctagatca cccaccattc
    14641 ctccaccaag tgcaagtatc ccatcgctgc gggtaaaatc attatctgct aaaaaatcgt
    14701 ataactcagc tgcttgttct aaagatttac tggtctcacc cgccggtacg attgaaagga
    14761 ctggttcaaa attagcttgt ctcaattgga acatgatttt ttctgcatat agtggagcaa
    14821 cgtttgtatc agtgatcaca gctacttttt gaggtctcca aatcgtttga agccatgatc
    14881 cagcctgttc tagtgcgcct ttttcaatat gaatatcgta tttttggtta tcaacatgta
    14941 cagtaagcat tcgtttcact tctttctttt aaaaagctgg aattaatcga gtgtctgaat
    15001 cttttccatt gcttctttca tgatcgcaac ttctttcatc atgcgtgagt aagtcttttc
    15061 attcaacgat tggggaccgt ctgaccaagc atttgcagga tcaggatgga tctctacgat
    15121 catgccatct gctccgcttg ccacacccgc acgagccatt ggtggtacaa gttcccaaat
    15181 tcctgtacca tgacttggat caacaatcac agggaaatga gttaattttt tcatcaatgg
    15241 gacagcactt aaatcaaacg tattacgtgt cgctgtttcg taagtccgaa tcccacgttc
    15301 gataaaaatg acaggagatt tgtcttcgac tgcaatgtat tctgcagcat taagccattc
    15361 attgatcgta ccggaaattc cacgtttcaa tccaacaggt ttacctgttt taccgacagc
    15421 agatagcagt ttaaaatttt gcatattacg tgcgccaatc tgtaggatat cgctgtactc
    15481 agccaccata tcgatatgcc cttcatccat cacttcagta atcactttca ttccaaattc
    15541 atcagccgct tgacggatgt atttcaatcc ttcttcttct aaaccttgga aagcatatgg
    15601 agaagtacgt ggtttgaagg caccacctcg cagaattttt gcgcccccgg ctttggccat
    15661 tcgcgcacat tctctgattt ggtctaatcc ttcgatagaa caaggaccag ccatcgtcac
    15721 gaaactgccg tcaccaattt ttactccgtc tacatccacg actgtattgc caggatggaa
    15781 ttctcgagaa gtcaatttgt atgtgtttaa aatacgcaca gcattttcta ctccttcata
    15841 gcgtgtaaat gctccttctt gtaaacttcg cgtatcacct tttagtccaa tcactactcg
    15901 ttctgttcct tgatcgattg agactttgaa tccttctttt tcgatatgat cgacgacttt
    15961 ttttatttgt tcttccgttg cttctttttt cataattact atcattgttt ttcccgcttt
    16021 cttttgttta cttatctatc ttggctgatt ttctctactt tttcaaggtg gttttacatt
    16081 aattcctact aaatgaccgt gtcctgttgt tctcattttc gctccttctt tcctacttat
    16141 gacccagata atcaacaaaa aaagatgtcc ctgtaggaaa ttg
//
LOCUS       DAXQKX010000058        15859 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.060, whole genome shotgun sequence.
ACCESSION   DAXQKX010000058 DAXQKX010000000
VERSION     DAXQKX010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15859
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.060"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            231..467
                     /locus_tag="ACF3MF_002130"
                     /pseudo
     CDS             231..467
                     /locus_tag="ACF3MF_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
     gene            complement(643..1784)
                     /locus_tag="ACF3MF_002131"
     CDS             complement(join(643..1556,1556..1784))
                     /locus_tag="ACF3MF_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFE3928090.1"
                     /translation="MAKAKKKFDEDFKKMILDLNQSGQSVEELAAQYGIATQTIYRWK
                     KLHTKNVATGMTEAEILAMKKEMARMQEENTIPKKGFNHIRSKVKMSDVFEFIQSNVH
                     DHDVKQMCTVLEAPKSSYYDWKKKKPSKRQSENKRLNRLISGIYFENKGIYGAPKIHK
                     ILVGRGETLSLKKVQILMRKLGLRSVTLKKYKPGKQAKVKSEGRKNLLNQDFTTTSIN
                     QKWVTDITYIHTLKDGWTYLSTIQDLHTKKVIGWKFGKQMTKELVIETLDNALLNQTP
                     SENLIIHSDLGSQYTSEAYEAKLNELNIRHSFSRKGCPYDNAGIESFHASLKKEEVYP
                     SKAYENFEAAYLALFQYIEGFYNRKRIHSSINYLTPNQMEELALQA"
     gene            1851..2834
                     /locus_tag="ACF3MF_002132"
                     /pseudo
     CDS             1851..2834
                     /locus_tag="ACF3MF_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008519 - ammonium channel activity
                     [Evidence IEA];
                     GO_process: GO:0072488 - ammonium transmembrane transport
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
     gene            2865..4292
                     /locus_tag="ACF3MF_002133"
     CDS             2865..4292
                     /locus_tag="ACF3MF_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFE3928091.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTTLSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMVANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            4315..5241
                     /gene="glsA"
                     /locus_tag="ACF3MF_002134"
     CDS             4315..5241
                     /gene="glsA"
                     /locus_tag="ACF3MF_002134"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HFE3928092.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WGGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            5449..6909
                     /locus_tag="ACF3MF_002135"
     CDS             5449..6909
                     /locus_tag="ACF3MF_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928093.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFDGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            7130..8893
                     /locus_tag="ACF3MF_002136"
     CDS             7130..8893
                     /locus_tag="ACF3MF_002136"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HFE3928094.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAIGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            8977..9435
                     /locus_tag="ACF3MF_002137"
     CDS             8977..9435
                     /locus_tag="ACF3MF_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HFE3928095.1"
                     /translation="MYQQVEEYVKKFQKKYPSYQSEKLGFFSFEDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLVYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            9544..10227
                     /locus_tag="ACF3MF_002138"
     CDS             9544..10227
                     /locus_tag="ACF3MF_002138"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HFE3928096.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEYINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            10374..10988
                     /locus_tag="ACF3MF_002139"
     CDS             10374..10988
                     /locus_tag="ACF3MF_002139"
                     /EC_number="1.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HFE3928097.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            11004..11210
                     /locus_tag="ACF3MF_002140"
     CDS             11004..11210
                     /locus_tag="ACF3MF_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928098.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     regulatory      11435..11601
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            11726..12889
                     /locus_tag="ACF3MF_002141"
     CDS             11726..12889
                     /locus_tag="ACF3MF_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFE3928099.1"
                     /translation="MKKRKKIDWWILGPYLTLSMIGLLEVYSASSYRLLQADENTKSL
                     LLRQLIFIFLSWSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGA
                     QRWISLFGIQFQPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPK
                     IAGALMILSIAWVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNH
                     AYERIATLRDSFIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIF
                     SIITEELGLIGALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVG
                     SIAGLMPMTGVPLPFVSYGGTSYLILSLGIGITLNISSKIQAEELPLYRPEKQ"
     gene            12981..13736
                     /locus_tag="ACF3MF_002142"
     CDS             12981..13736
                     /locus_tag="ACF3MF_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFE3928100.1"
                     /translation="MKVSQKIILSILLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEP
                     KSVPTTLNVALIGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGM
                     NKINAAYSYGGVDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSL
                     DLDGVYINKGEQVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFK
                     LPKAVGKLLGSIQTNLPESVLLDCGMDFLKDIC"
     gene            13794..15833
                     /locus_tag="ACF3MF_002143"
     CDS             13794..15833
                     /locus_tag="ACF3MF_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HFE3928101.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEQPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSYQVTRVSSDASQVDLKTALIYSDNIYAAQEMLKMGEKKLRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLINPIQQAAMYSVFANNGTLVY
                     PKLIADKETKDKKNVIGETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGKENSFLFAFNPDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
BASE COUNT         5153 a         2696 c         3311 g         4699 t
ORIGIN      
        1 tgaaaaaata tctttaaaaa taaaaaaaga cgaaaataaa cggttttcta taaaaagaag
       61 accgattatt ttttgtcttt atttgtgtga aaaacgaaaa agagcacaac acatcaagct
      121 tttattaatt gtctgtcttt tataaatgca agtattaatt caaaaaaaca gaagaaaaaa
      181 acaactacac cttcttttat actcgtaatc gtagaaagga ggcgaaaaaa atgaatacat
      241 tacctatcaa tacaggagat acagcattca tgattttatg tacagcaatg gtttgcctga
      301 tgactcctgg tctagcattt ttttacggcg gattagcacg gaagaataat atactaacga
      361 tcatgtctca atcttttctc tccgttggga taacaacgat tatgtgggta tttggtggat
      421 tcggattggc ctttggacgg gatatcggcg gtgttattgg aaaccctgga tttgagtcaa
      481 tacctcggac acgatttgtg agaatttttt cgagattcca gcgggtgagt atctcatcgt
      541 ttcgaccagc ggtcaaacca aaaccgtttg accgctgatc gaagcgatga agttgaaacc
      601 ctgtggaaat ctcgccaaaa aaatgtaagt ggtagctagg aactaagctt gcaatgccaa
      661 ctcctccatc tgatttggtg ttaaatagtt gatactacta tggattcgct tgcgattgta
      721 aaatccttca atgtattgaa ataacgctaa ataagcagct tcaaagtttt catacgcttt
      781 tgatggatag acttcttctt ttttgagtga ggcgtgaaac gattcgatac cggcattatc
      841 gtagggacag cccttacgac tgaaggagtg ccgaatgttc aattcattca gctttgcctc
      901 ataggcttcg ctagtgtact gagaacccaa atctgagtgg atgatcaagt tctcggaggg
      961 tgtttggttt aagagcgcat tgtcaagggt ttcgataacc aattctttcg tcatctgctt
     1021 gccaaacttc caaccgatga ctttctttgt gtggaggtct tgaatagtgg agaggtaggt
     1081 ccagccatct tttagggtat gaatataggt aatatctgtc acccattttt gattgatcga
     1141 cgtagtggta aaatcttggt ttaacaggtt tttacgtcct tcacttttaa ctttcgcttg
     1201 tttgccaggc ttgtacttct tgagggtgac tgaacgcaag cctaattttc tcatcagtat
     1261 ttgtactttc tttaaggaca aggtctcgcc acggccaaca agaatcttat gaattttagg
     1321 cgcaccatag atacccttgt tttcaaagta gattcctgaa atcaagcggt ttaagcgttt
     1381 gttttctgat tggcgcttgg aaggtttctt tttcttccag tcatagtagc tggatttcgg
     1441 tgcttccaaa acggtacaca tttgttttac gtcatgatca tgaacatttg attgaataaa
     1501 ttcgaagaca tcactcattt ttacttttga gcgaatatgg ttaaagcctt ttttaggata
     1561 gtgttttcct cctgcatgcg ggccatttcc tttttcatcg ctaggatttc tgcctcagtc
     1621 atgccggttg ctacattctt tgtatgaagc ttcttccaac gataaatcgt ttgtgtagcg
     1681 ataccatatt gcgctgccag ttcttcgacc gattggccag actggtttaa atctaagatc
     1741 atcttcttaa agtcttcatc aaattttttc ttggcttttg ccatcgtgga cacgtccttt
     1801 tcttagtagt tagattctac caaatcgtgt ccatgaaatc atcctaacat cacccggcag
     1861 atttcttttt gatgagacat gttacaagct tccccaacat gtttcatggt gcaacgattc
     1921 catttttaat gttctttctt taccaactga tgtttatcgt gattaccgtt cctttgatga
     1981 caggagcttt tgcaggaaga ttgaatttaa aaggctatat tatacttgtt attttttgga
     2041 atctgctgat ttatttccct gtttgccact ggatatgggg cggcggattt ttggatcaga
     2101 tgggatttag agatttcgct ggtggagcag tcatccacac gacagctgga ttcggctctt
     2161 tagcatgtat cctcacactt ggtcaaagaa agattccttt aggagaaaga agtcagcata
     2221 gcagtcttat ggcagctgct atcggtacag gactgctttg gtttggctgg ttcggtttta
     2281 attccggtgg tgcacttcga gcagatgaac aagcagtcaa tgcatttggt tcaacattca
     2341 tcgctcttgc atttgcgatg attacttggc tgatcattgc aaaagtaaaa ggaaatggct
     2401 ttgattttgt cgacgtacta acaggatccg ttgctggatt ggcagccatt acgccttgtg
     2461 ccggttatgt agaagcaaaa agtgccatgc tgattgggat cattgcgggt atcgtctgtc
     2521 atgctgctgt tgattttcgt aaaaagaaac aatgggatga tgcacttgat gtgtggggtg
     2581 ttcatggcat gggcggattc acaggtacga ttctgatagg gatctttgca tctaacagcc
     2641 atctactaac aaatccaagc agctggtact tcttagggat tcaagtgatt agtgtcatca
     2701 ttactgccgt gtatgcctat gtgctgacaa cagtgatttt aaaatcggcg atgcatttta
     2761 caacgatcac tactacaaaa gaagaacaag aagaaggatt ggactttttc ttctttggca
     2821 acaaactcaa ttgaaacaaa ttcaaataga aaagaggaag attcatgcaa caaagcaaaa
     2881 cgaaaattcc tgcaaaaaaa ttaacgttct ttggcttttt ggctatgacc atctcaatgg
     2941 tcgtttcatt atatgaatat cccacattcg cgacctcagg cttcagctta gtatttttct
     3001 tgttattagg cggtttgcta tggtttatcc ctgtggcatt gtgcgcagca gagatggcaa
     3061 cggtgaaagg atgggaaaaa ggcggtgtct atacttgggt cagtcgcaca ttgggaaaac
     3121 gattcggttt tgccgcaatc tttttccaat ggtttgagat aacagttggc tacttgacca
     3181 tgctgtattt cttaactggt gcattatcct atgcaacggg tattggtgct atacaaaaca
     3241 ataaatatct gaaattggca atcctattga ttattttctg ggctatttta ctctcacagt
     3301 taaaaggaac caaatacact tcattgattg ctcggatcgg ttttgtagct ggtatcttgt
     3361 tgccagcatt agtcctgttt ggcttaggga tccattatgt cgcttcaggc gctccactac
     3421 aaacgacact gtctatgaaa acattgattc ctgatttttc gaaattgcct acgctggttg
     3481 tttttgtttc ctttatttta gcatatatgg gcgtagaaac atctgccagt catgcaaatg
     3541 aaatggaaaa ccctaaaaag gattatccat tagcaatgtt tgtattggtt attctggcaa
     3601 tcattttaga tacttttggc ggattgaccg tcgctactac agtacctcaa catggtttgt
     3661 ctcttaatac aggggtgatt caatcgttag aattcctatt aagacacatt gatccaaatc
     3721 ttgcatggat tgcgaaaatt cttgcgattc ttgtttgttt aggtgtcatc ggagaaattg
     3781 cttcttgggt aacctctcct tcaaaagcac ttcacgtagc agcagaagaa ggattacttc
     3841 ctgaatattt tgcaaaagaa aacacacacg gtgttcctgc tcatttgatg gtcgccaatg
     3901 ggatcgttgc aacaatctgg gcagccgtct ttacattaag cggcgggggg aataatcttt
     3961 catttcttgc agcgatgtca ttgactgttg taatctacct gatgttgtac tttatgtttt
     4021 tcgcgggcta tttgaagctg gtttttaaag atgacagtct tgaaagagcc tatcaggttc
     4081 caggcggaaa agttgtaaaa gtaatcgttg cttgtttagg tcttttgact tcactttttg
     4141 ctttttgtat ctcatttgtt ccacctgcta gtatcgcagc tggacagcat gggatttatg
     4201 aaacgattct gattgtttct tatcttatcg tcttagttat tccatttacg atctacgcat
     4261 gccgtcataa attccagcat gcagaaaaat aaaaaatgaa agctggttat tcaaatggaa
     4321 gtaaaagaat tagaacaatt gattggaaaa aatttccact attatcaaac aggacaagtg
     4381 gcggattaca ttccagcatt agctgaagtg gatcctaaac aattaggtat ggcgatttat
     4441 gatttggata caaaacaact gattgaggga ggagatgccg atgtgcgctt tgccatcgaa
     4501 agcatgtcaa aagttcccgt attgttatta gcaatcaaag acaacggaat agaaaaagtc
     4561 tttcaaacaa tcaacacgga accaaccggt tttgccttca attctatcat gaatatggaa
     4621 atcaatcatc gcaaacatcc aatgaatcct tttgttaatg caggagcgat tgcaacaacc
     4681 tcgttgattg ccggtaaaga tgcagatgaa aaatttgagc gaatcttgtc atttatgaaa
     4741 gagatctgtg atgatcctaa tatcacattg aatgaagaaa tctatcattc tgaatcaaga
     4801 acaggtgata tcaatcgctc tcttgcttac tatatgaaag gtaatcaaat gatcgaagga
     4861 gacgtaccgg agatactcga tgcttatttc agacaatgct ccctcaatgt caccgctaca
     4921 ggcatagcaa aattagctgc tgtgctggca aataaaggaa ttgctccttg gggtggcaaa
     4981 caaatcatta ctgaagaaag tgctacaatc gtcaaatcaa ttatgacaac tgctggtttg
     5041 tatgatgaat caggagagtt ttccgtccat gttggtgtac ctgcaaaaag cggtgtaggc
     5101 ggcgggttga tggcagctgt gccaaatcgt tacggcatag gtgtcttcag cccggcacta
     5161 gatccatttg gtaacagcgc agctggtatc caattgttga aagatgtagt caaagaacta
     5221 gacgctgaca tctttgaata accattcttg aaagaggctg gggtaaaagt ccaaacggct
     5281 caaagttacc tacaatgagg ctgaaattgt gagcttgttt gacttttgtc ccagtttctt
     5341 tttttattgg tttttgaaag ggcttttcta aataaaaagg aaacaaaaat atgatttaca
     5401 gatatgatta aataaactca taagaaaaac tggaggcgtg tatcaggaat gctggaaaat
     5461 tacatcgagc gaaatatatt tagaaaagtg tatctgtgtg aacaattatt tgaattccaa
     5521 gaaatagata tcgaacaaac agctatttct ctaagggtga ctacaccaac gatccttcac
     5581 gatctagaaa gtctagccga gtgtctagaa tattgtataa aagaacaagt aagagagaag
     5641 cataagtata aactcgtatt caaacatggt attgctcttt ctgagctcac acagtttctg
     5701 tacggtcaat cttatttttt aaagttttta agttattatt ttgatggtat attcacgagt
     5761 acagaactgg ctgatcttga atttatttct ttgagcaaag tatatacaat caaaaaaatc
     5821 gtattggatt tttttaaaga aaatgattat ttgaaaaata aagaaatcat tatcccagaa
     5881 tttgactcgc ggaacatctt gctagcttta gtacgctatg tcaattggga aggctatgaa
     5941 aataaaaatc cgtatgtaga agaagcttgt aacgagttga ttgattatgt agagactcat
     6001 ttttttaaaa gaagatattc ggaagatgaa aagtccttta tcatacgagg aatagagatc
     6061 gcaatcggaa gaaaggcatt tccccttgga ctgaaagaag aagataagaa aagcgcagaa
     6121 acgaagccgt tatttcaatt agtttgtcaa ggattggaag agcaaaaagg aattctagac
     6181 ttacaagaag aagatgtcta ttatattttt tccttgttca acagtagaaa ttataccaat
     6241 gagaacatgg agctgttaag aaaagatttc gaagttgttt ataaaaattt tgttctcaat
     6301 gacctatcac tgaatgaatt gattttacag attattagta tcgctgaaat cgacgatgca
     6361 gaaaatttta ttttcaagca atccttttta caatttgtcc gtacgttgtg ggcagatgga
     6421 caagtatttt taccggaaag gatctatctt ctatcagaaa aagaacaact tctgtacgga
     6481 aaaattgtag aaatattgga agagtggaaa aagaaaaatc aaatccaact aagatggaat
     6541 gaaaatttca ttcgaaaatt cgtcaaaagt ctttctttga tcaacagtga acaagcgggg
     6601 agacaggaaa tagaaatttt tgttgtttca gaaagttcag tcaaacaatt tttttatcga
     6661 acccaatttc atttgtatgc ggaagaaggc atcgccgaaa taaatcctat tttatttcgt
     6721 tcattagaag aattgcctga tgaatgtcta tgtgcgaaaa aaagagtggt tttgtgcgat
     6781 gctgctagct atcaaaatgg attagaaact gaaaagacaa agatctatcc aatctcatta
     6841 aaaggtgcaa acatccattt gtatcatatt gctcaggaac ttcacctatt aaaaaaacat
     6901 atttcttgat gagaccttaa ttaggagacc ttctacaaag ctttttaatt gtctgtagaa
     6961 ggtttttatt tgagtcctga ttcgtgcgaa gatctactta tataacaagc tttctctgaa
     7021 atttttttaa aatgctattg acttagagtc aactctaagt agtagaatag ataaagtgta
     7081 acaaatctat tttcattaaa agaagatagt acggaggaga gaatgtatta tgagtacagt
     7141 attacatgta ttggatgcaa tcaatagccc cgcagatgtc aaaaaattat ctgttgagga
     7201 aatgaaacag ttggcagaag agatgcgcca aaaaatcttg caaaaggaca gcgatgtagg
     7261 tgggcacgtt ggtccgaatc taggtgtagt agaattaacg attgcgtttc attatgtatt
     7321 tgattcacca aaggataaaa tcgtttggga tgtttcccat cagtcttatg gtcataagct
     7381 tttaactggt cgaaaaaatg gttttgaaaa aggacattac cgtgaagtga gcggatattc
     7441 caaccaacat gaaagtaaac atgactattt tacagtgggg cacacatcta catctatcag
     7501 cttagcaaca ggtttagcta aagcgagaga tctgaagaaa gaatcaggaa atgtggtagc
     7561 atttatcggt gacggctccc taagtggtgg cttagctttt gaaggattga acaatggtgg
     7621 tgttttacaa tccaatctaa tcgtattagt aaacgataat gagatgtcta ttgatgagaa
     7681 ccatggcagt ttatataaaa acttagctga gcttcgtcaa accaacggta aaagcagcaa
     7741 taacctattt aaagcaatag gatttgatta tcgttacgtg gataatggaa acgatctgga
     7801 aacggtgatc cgtttatttg aagaagtaaa agatattgat catccgattg tacttcacgt
     7861 acatacggaa aaaggtcgcg gttatcagcc ggcaatcgat aataaaatga aatatcattg
     7921 gcatgtacca tttgatctgt ccaccgggga ggcaaagcaa gtaacttctg gagaaacatt
     7981 taatatgatc atcatggatt atttggataa gaaaatgcaa acaagtacag ctcctattgc
     8041 cgcagtcaat gcagcgatac caggcgcctt tggactgaaa acattccaag aaaaacatcc
     8101 agatcattat tttgacgtgg ggatcgctga acagcactct atcactttcg cttctgcttt
     8161 ggcttctcag ggagtacgtc cagtcgtctt ccaatcaagt actttcttgc aacgggcata
     8221 tgatcaatta tcacatgatt tagcgatcaa cgagaatcca gtgattattt tagtcggtgg
     8281 cggaacgatc tcagctagtg accgaacaca ccaaggaaca tttgacattc cttacttatc
     8341 aagtatcccg aacatcaaat atcttgctcc agcaacaaaa gaggatatga tctctatgct
     8401 agattgggcg ttcgaacaaa cagcgcagcc tgtagcaatc cggattccta cacatggtgt
     8461 agaacatggt acagctatcg caaatgatta tagtattcca gcctatcaaa cagtaaataa
     8521 tggaggaaaa gtagcaattt tagctttagg cggttttctt gaattaggaa aagaaacagt
     8581 aaaagctttt agaaaaaaag gaatcgaagc aacgttgatc aatccaggaa cgatcacaga
     8641 aaatgacgta gaaacattag ataaattaaa agaaacacat gaattagtca tcacattaga
     8701 agatggtagt ttgtcaggag gatttggcga aaatatcagt cgttattatg gtgattcttc
     8761 aatgaacgta ttaaattttg gtgcagagaa agaattcacg gatagcgttc ctgtagggca
     8821 gctttatgaa cgttatcatt taacaccaaa acaaatcgtt gaagatagtc tgcgtgtctt
     8881 gaatattcaa taattcatta tgctcaccat ccagataatt gtttatacta gtatctggat
     8941 ggttttttca ttataaaaag caatggggtg gatgttatgt atcagcaagt agaagaatat
     9001 gtcaaaaagt tccaaaaaaa atatcctagt tatcaatcag aaaaattagg tttcttttca
     9061 tttgaggata cagaaaaaat ggcagacgag ttgagcgaac tagttgtaaa aaagataaag
     9121 actggtacat caagtggtta cgatctgtat aaacaagaga atgagccttt accaaaagtt
     9181 ggtcaattag acgtggtcct gaatggaaaa aatgaaccag tttgtatcat caaaaatata
     9241 aatgtgacca tcttgccttt tagtgaagtc acgaaagagc atgcttggaa agaaggagaa
     9301 ggggatcgga cattagttta ttggcggaaa gtccatgctg agttttttaa acatgcttat
     9361 aaagaagcgt tgaacataga atttacagaa gagaagctgg tcgtatacga agaatttgaa
     9421 gtaattttct tttagtaaga aaggtctgct gaaagaaata gctcattatt gactcctgaa
     9481 tagaaaaggg tttcattttt atatgaagct gtatttttat ataacattac tggaggagat
     9541 attgtggata cactggaaca aatcaaaggc ggagtcgtcg tttcttgtca agctttggaa
     9601 aacgagccgc tacacagttc ttttattatg gggagaatgg ctttggctgc aaaagaaggc
     9661 ggagcagttg gtattcgagc aaatacgaca gaatatatca atgaaatcaa gcgaatcgtt
     9721 gatttaccgg taatagggat tatcaaaaga gattacgatg ggtcagaagt gtttattact
     9781 gcgacagaaa aagaagtgga agaacttttg gagacgcaag cagaaatcat tgcactggat
     9841 gcaacttctc gtaaacgtcc gacagaaaaa acaactgctg aacttgtcca aatgattcac
     9901 gaacacggtc ggttagctat ggcagatatt tcgacttttg aggaagcgct tcaagcgcaa
     9961 gaagatggtt ttgatctttt gtctacgact ttagcaggct atacagaata ttcacgaaag
    10021 acgcagacac ctgattttga tttattgaat caaatcatag aacaagtcga tatcccagta
    10081 attatggaag gacatactga ctctcctgaa caagtagaga aagcatatga attaggtgct
    10141 ttttcagtcg tagttggatc tattatcacc cgtccgcaat tgatcactaa aagatatgtc
    10201 gaagccgcaa gtaaagcaaa taactaaaaa acacgcacgg cacagattct tgacaaaaaa
    10261 gaaaaattga tagatagttt aaagcagatt ctaagaagat gaaaaaagca ttacttttca
    10321 ttttgtcttc aagatctgct ttttaacgaa ttttatagaa agaaggcgaa accatgtttg
    10381 aacggagtcc ttcagaattg acagaacgtg aaaattacaa gttgctgatt ggttcagtca
    10441 tccctagacc agtagcagta gtaacgacta aatcagcaaa agatatagtg aatatcgcac
    10501 ccttcagtta cttcaatatc gtcagttcga atcgacccat cttatccttg gcgatccaga
    10561 gaaaacaaga tgcagtaaaa gacacagcaa agaatattct tgagacaaga gaagctgtta
    10621 tccatatcct tgatgaggac aacgtagaag aagtaaataa aacagcagcc aatctgccta
    10681 atgaggaaag cgaactgtac ctgactgact tgactttaac tgattcagta atcatttcag
    10741 taccagcatt gacagaagca aaagttcgtt ttgaaacatc cttatatgaa catgtcgaga
    10801 tacggaataa aaataaagta acagctgatt tatttttgct agaagtacag aaatatcatt
    10861 taaatgaaac agtctatgat gataagacag gaaggatcga tccaagaaaa ttgaatgctg
    10921 taagccgttt ggcaggaaat gattatgcag caataggaga aattttcacg attgcacgtc
    10981 ccgaataaaa aggagcacta gttatgttaa aaataagcta taaaccatcg acagattcaa
    11041 aagaaatgaa aaaagaatat gaaacagtga atgattttct gcaagggcag tacttagaag
    11101 ttccgccatt gcaagaccat tttgtcgtta ctactgttac tttagatggt aaggaaatag
    11161 aaatgccaga tcaaacgatt agcggattgt ttaattactt taacaaataa atatttattc
    11221 cgaaaagtga aaaaacatat aaaaaaacac ataaaactaa aaaattatca aagaatcctg
    11281 gtgcaactga aagaatttgc aacgggattc tttcaactta tttgttattt ttttctaaaa
    11341 aatattaaag attgttaaat ttcactattt catttcaaat tccattgcct aatcattagg
    11401 aaaagtctat catgaactcg taaatagaat atagtaataa ccttgttagg tgaggctcct
    11461 atacaaacat aggctgttgc ccagaaacgt cgaaagtcgc caatgggtaa aacagaaact
    11521 gtcggattaa ggctttttcc aatagctaag aatgttttct ttacgttgta tagtgctaaa
    11581 actcggacga tgagatgatg ctaggtcaga attcttgttc gaaaaggttt ctgacctttt
    11641 ctttatattt ttgtgactga cttatttgat gagacaaact cgctcctcac ctgacaagtg
    11701 gattgctgtg tgaggaggag atgcggtgaa aaaaagaaaa aagatcgatt ggtggatttt
    11761 gggtccttat ttgactttgt ccatgatcgg tcttttagaa gtatacagtg ccagttctta
    11821 tcgtttattg caagccgatg aaaatacaaa aagtctatta ttgcgtcaac taattttcat
    11881 atttttgagt tggagcgtga tcttcttagc tcgttcagtc aaactacact atttacttca
    11941 ccctaaaata gcaggatacg gtttagcctt atcgattttc tttttagtat tagtaagaat
    12001 agggatattc ggtgtcactg tcaacggcgc acaacgttgg atctctctgt ttggcattca
    12061 attccagcct tctgaactgg caaatctttt tttgattttt tatttaagct ggttttttcg
    12121 tgacggaaat agtagcccaa aagatctaaa aaaaccattc ctgattacag taggtataac
    12181 ttttctgatt ttatttcagc caaagattgc tggagcattg atgatccttt cgattgcgtg
    12241 ggtcatattt tgggcagcgg cggttccatt taaaaaaggg atctatctaa tcgttacttt
    12301 ttctgcattg ctgattggag cagcaggcgg ggtattatat ttaggaaata aaggttggct
    12361 tccacagatg tttaatcatg cttatgaaag gatcgcgact ttaagagatt cttttatcga
    12421 tagtcatggt gcgggctatc aaatgaccca ttcgttttat gcactatata atggtggcat
    12481 atttgggcgg ggattaggaa atagtatcac aaaaaaaggg tatcttccag agacagaaac
    12541 agactttatt ttttcgatta ttacagaaga gcttgggcta atcggtgcat tgtgtgtgct
    12601 tttcttattg ttctcattat gcatgagaat cttttgttta agcagtcgct gtaaaaatca
    12661 gcaagctgga ttgtttcttt taggattcgg aactttgcta ttcgttcaga cgataatgaa
    12721 cgtgggaagt atcgcggggc tgatgccaat gactggtgtg ccattgccat ttgttagcta
    12781 cggaggaaca agttatctga tcctttcttt aggaatcgga atcacgttga atatttcttc
    12841 aaagatacag gccgaagagt tgccgctcta tcgacctgaa aaacaataaa gagaaactga
    12901 gaaactctca gtttgaatta tcataaagta caatctttta tttttcaagc gagaggttct
    12961 tttagaaaga ggaattcgca atgaaagtat ctcaaaaaat catattatct attttgttac
    13021 tgcttacatt agtagttggc tatttttcga ttgagtttat ccatggattt tcgtctgcaa
    13081 aacagagttc aactgtgaaa aaggtagagc cgaaaagtgt ccctaccaca ctaaatgtgg
    13141 ctttgattgg ttcagatgct cgttcgaaag acgaaaacgg tcgctcggat tcacttctgg
    13201 ttgcacaata caaccagaaa acacaacaag caaaactgat ctctatcatg agagattcat
    13261 atgtcgatat tccaggttac ggaatgaata agataaatgc agcttactct tatgggggag
    13321 ttgatttatt aaatcaaaca ttaaaggaaa atttcaaatt tgaagctccc tattatgcaa
    13381 gtatcacatt tcaagatttt atcgattgcg ttaatgaact gtttcctggt ggagtcaaga
    13441 tcgatgcaga aaaatctcta gatttagatg gcgtatatat aaacaaagga gagcaagtga
    13501 tggatggtaa tactttactc cagtatgctc gatttcggga agacaaagaa ggagacttcg
    13561 ggaggatcag aaggcagcag caagtgatca aagctatctc tcagcagctg aaagacgtaa
    13621 cttcaatatt caagctaccc aaagcggttg ggaaattact tggtagtatc caaacgaacc
    13681 ttccagaaag tgtgcttctg gattgtggta tggatttcct caaagacata tgttagaata
    13741 aacaggtata aatagtgaaa taaaggaatg acaagcaaga gaaggaggaa aaaatgaaaa
    13801 gaagtgacaa gcacggcaaa aatcgaacag gcgcttatat tgccggcgca gtgatcttaa
    13861 tagcagctgc gggtggcggt tatttttact accagcacta tcaagaaacc caagcagtag
    13921 aagctggaga aaagacagtt gagcaatttg tccaagcttt gaacaaggga gattataaca
    13981 aagctgcaga aatgacatca aaaaaggcgg caaataaaag tgcattatct gaaaaagaga
    14041 tcttagataa ataccagaat atatacggtg ctgctgatgt caaaggactt cagatatcga
    14101 atctaaaagt agataaaaaa gacgattcta cttacagttt ttcatataaa gcaaagatga
    14161 atacctcatt aggtgaattg aaagatcttt cttataaagg aacattagac agaaatgatg
    14221 gtcaaaccac gatcaactgg caacccaact tggtttttcc agaaatggaa ggaaatgaca
    14281 aagtaagcct gaccacacaa gaagcagcaa gagggaatat tatagatcga aatggtgaac
    14341 cattagcaac aacaggcaaa ctaaaacaat taggagtcgt tccaagtaaa cttggagatg
    14401 gaggcgaaaa aacagccaat atcaaagcga ttgcttcctc cttcgactta acagaagatg
    14461 ctatcaatca ggcgatttca caaagctggg tacaacccga ttactttgtc ccattgaaaa
    14521 tcattgatgg agcaacgcca gaacttccag ctggagctac cattcaagaa gtagacggca
    14581 gatattatcc tttgggtgaa gcagctgctc agctgattgg ttacgtggga gatatcacag
    14641 cagaagatat tgataagaat ccagaattaa gcagtaatgg aaaaatcggt cgctcaggtt
    14701 tggagatggc ttttgataag gatcttcgtg ggacaacagg tgggaaatta agcattacag
    14761 atgcagacgg tgtagagaaa aaagttctga tcgaacatga agttcaaaat ggcaaagata
    14821 tcaaattgac aatcgatgcg aaggcacaaa aaacagcttt tgacagtcta ggaggaaaag
    14881 ctggatcaac tgttgcgaca acgccaaaaa ccggtgatct tcttgcgctt gctagctctc
    14941 caagctatga tccaaacaaa atgacaaacg ggatctcaca agaagattac aaagcttatg
    15001 aagaaaatcc tgaacagcca ttcatcagcc gatttgcgac aggttatgct cctggatcta
    15061 cgtttaaaat gattacagca gcaatcggtc tcgacaacgg cactatcgat ccaaatgaag
    15121 tgttgacgat caacgggctt aaatggcaaa aagacagttc ttggggatct tatcaagtaa
    15181 cgcgtgtcag tagtgatgca tcacaagtag acttaaaaac tgctttgatc tattccgata
    15241 atatatatgc ggcacaagaa atgttgaaaa tgggtgagaa aaaattgcgt acaggcttag
    15301 ataaattcat ttttggtgaa gaccttgatt tgccaattag tatgaatcca gcacaaattt
    15361 ctaatgaaga tagctttaac tcagatatct tgctagctga tactggatat ggacagggcg
    15421 aacttctaat taatcctatc cagcaagcag caatgtattc tgtttttgcc aacaatggca
    15481 cacttgtcta tcctaaattg attgcagata aagagacaaa agataagaag aatgtcatcg
    15541 gcgaaacagc agtacaaacg atcgtgccag atctgagaga agttgtgcaa gatgtaaatg
    15601 gtacagcaca ttctctttct gctttaggga ttccgttggc agcgaaaact ggtacagcgg
    15661 aaatcaaaga aaaacaggat gtaaagggga aagagaacag tttcttgttt gctttcaatc
    15721 ctgataacca aggttatatg atggtcagca tgttggaaaa taaagaagat gatgattcag
    15781 caaccaaacg agcatcggaa ctattgcaat acctcaacca aaattatcaa taaaaaattg
    15841 ctttttaagt acagtaaaa
//
LOCUS       DAXQKX010000059        15424 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.061, whole genome shotgun sequence.
ACCESSION   DAXQKX010000059 DAXQKX010000000
VERSION     DAXQKX010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.061"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            6..863
                     /locus_tag="ACF3MF_002144"
     CDS             6..863
                     /locus_tag="ACF3MF_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFE3928102.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            885..1394
                     /locus_tag="ACF3MF_002145"
     CDS             885..1394
                     /locus_tag="ACF3MF_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HFE3928103.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            1431..1832
                     /locus_tag="ACF3MF_002146"
     CDS             1431..1832
                     /locus_tag="ACF3MF_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928104.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            1944..2297
                     /locus_tag="ACF3MF_002147"
     CDS             1944..2297
                     /locus_tag="ACF3MF_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928105.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            2331..2774
                     /locus_tag="ACF3MF_002148"
     CDS             2331..2774
                     /locus_tag="ACF3MF_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFE3928106.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            2791..3876
                     /gene="uxuA"
                     /locus_tag="ACF3MF_002149"
     CDS             2791..3876
                     /gene="uxuA"
                     /locus_tag="ACF3MF_002149"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFE3928107.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            3869..4582
                     /locus_tag="ACF3MF_002150"
     CDS             3869..4582
                     /locus_tag="ACF3MF_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFE3928108.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(4789..4938)
                     /locus_tag="ACF3MF_002151"
     CDS             complement(4789..4938)
                     /locus_tag="ACF3MF_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928109.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            5334..5534
                     /locus_tag="ACF3MF_002152"
     CDS             5334..5534
                     /locus_tag="ACF3MF_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFE3928110.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
     gene            6102..6665
                     /locus_tag="ACF3MF_002153"
     CDS             6102..6665
                     /locus_tag="ACF3MF_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928111.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(6726..7091)
                     /locus_tag="ACF3MF_002154"
     CDS             complement(6726..7091)
                     /locus_tag="ACF3MF_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02328 family protein"
                     /protein_id="HFE3928112.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(7167..7412)
                     /locus_tag="ACF3MF_002155"
     CDS             complement(7167..7412)
                     /locus_tag="ACF3MF_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFE3928113.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(7482..7736)
                     /locus_tag="ACF3MF_002156"
     CDS             complement(7482..7736)
                     /locus_tag="ACF3MF_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928114.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(7900..8223)
                     /locus_tag="ACF3MF_002157"
     CDS             complement(7900..8223)
                     /locus_tag="ACF3MF_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928115.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            8410..8483
                     /locus_tag="ACF3MF_002158"
     tRNA            8410..8483
                     /locus_tag="ACF3MF_002158"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:8444..8446,aa:Ile,seq:cat)
     gene            complement(8868..9365)
                     /locus_tag="ACF3MF_002159"
     CDS             complement(8868..9365)
                     /locus_tag="ACF3MF_002159"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase family cysteine hydrolase"
                     /protein_id="HFE3928116.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(9405..10214)
                     /locus_tag="ACF3MF_002160"
     CDS             complement(9405..10214)
                     /locus_tag="ACF3MF_002160"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFE3928117.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            10548..11405
                     /locus_tag="ACF3MF_002161"
     CDS             10548..11405
                     /locus_tag="ACF3MF_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HFE3928118.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            11398..12300
                     /locus_tag="ACF3MF_002162"
     CDS             11398..12300
                     /locus_tag="ACF3MF_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HFE3928119.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            12333..12683
                     /locus_tag="ACF3MF_002163"
     CDS             12333..12683
                     /locus_tag="ACF3MF_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFE3928120.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            12732..13655
                     /locus_tag="ACF3MF_002164"
     CDS             12732..13655
                     /locus_tag="ACF3MF_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFE3928121.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            13733..14626
                     /locus_tag="ACF3MF_002165"
     CDS             13733..14626
                     /locus_tag="ACF3MF_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFE3928122.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            14664..15227
                     /gene="amaP"
                     /locus_tag="ACF3MF_002166"
     CDS             14664..15227
                     /gene="amaP"
                     /locus_tag="ACF3MF_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFE3928123.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            15241..>15424
                     /locus_tag="ACF3MF_002167"
     CDS             15241..>15424
                     /locus_tag="ACF3MF_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFE3928124.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFK"
BASE COUNT         5361 a         2519 c         3065 g         4479 t
ORIGIN      
        1 gggaaatggc tgaaataatg gataatcaaa caggtgctcc tgaagaaatc acgaaaaaag
       61 atgtaacaaa agcctatctg agatggcatt ttgcaaacga aattcctcac tcttttgaac
      121 gttacttggc gccatcacta ctatacggaa tgatgccaat cttgaaaaaa ctttataaag
      181 atgaagactc tttaaaagca gcatataaac ggcagttact gttcttcaac actcaattaa
      241 gctggggtgg cggtgtgatt actggcctaa tgtcttctat ggaacagcaa agagcagaag
      301 aagagtatga agaaaaagag atcttgatgc aggatgactt gatgtataac acgaaagcgg
      361 gattgatggg ggcactagca ggaatcggag atgcaatcga ttcaggaacc gtccaatata
      421 tttttatcgc aatcgcggta ccttgggcac aacagggaag tcctttaggc gcactttttc
      481 cttttatctg ctttgggttg tatcaggttt tactaggggt atttttcgca agacaagctt
      541 tcactatggg ccgtaatgct acaggcctaa tgcaaaacac tggtgttcag acagcgattg
      601 aaatgctatc agttttaggg ttgtttatga tgggggtgct tgcgggaaac tatgtaaaag
      661 tagaatcttc attgaaattt gcgatatccg gacgtgagtt tgttatccag gaaattcttg
      721 atcaaatcgt gccagggata ttacctttag ctgtcgtaat gggtgtgtac ttgttctata
      781 cgaaaaaagg attgaaagtc acacaagcat tattatggct gactggaata ttaattgtgc
      841 tagcaggaat cggtatttta taaaaagaag ggaacgtgaa taagatgggt gtagtcaatt
      901 tagcgcgtgt ggatgagcgt ttgatccatg ggcaagtaat ggtaacgtta tctcaaaaaa
      961 gtggagtgaa ttccattttt gttgtagacg aagttgtagc aaaagataaa tttatgagag
     1021 atctttacaa aaatgcagga agccgtacag gacaaaaaac aattgtcatt acaccagaga
     1081 aagctaaatt ctattgggat gaatatcaat ttaaagaata caattgtatt ttgatcgcaa
     1141 aaacagtcca aacgatttac gacttagtaa aacacggaat ccccatggaa gaattgaata
     1201 ttggagggat tgctcaaaaa aatcctgata cagatctttt agtgacgaaa tctgtttatt
     1261 taaataaatc agatgctgaa aaattgaaag aaatgaatga acaatatggc gtaaagaata
     1321 tttattttca agccactcca tctgcaccta aaacaggatt aaaagatgta ttgaacaagt
     1381 ttgatttgtc ataaacaaat gcttagaaaa aagataaaga gggcgaaaaa atgaagaaga
     1441 acgagctgtt tcgtgattgg gaatttcgtt atcgctatat ttaccgtaag cgccgtacaa
     1501 aaaagagtaa acagcgtttt ctttcagcat tagtatcaga tatttacagt atgagaacag
     1561 atgtgacagt cattgcttac gatacgctag cctaccgatc aaaaaatatt tatgttggag
     1621 atatcgaaaa agcagagaaa gttatctgta cttattacga tacacccgtt catgcattag
     1681 gaagttattt catgtttgat tggaaagacc aaaggaaaaa aacaatctac tctatattat
     1741 tgtccttcat tttgttgttc agtttaggtt ggtggggaat gatgatatat aacaaaaatc
     1801 ctcatcacgt attcgatctg ctatccgtat aaacaggtat cactgtacta gcatttggga
     1861 gctacttttt cttattggga aaagcagctc gcggatggcc tagcagacaa acttttattc
     1921 gaaatacttc atccatatta acgatgctag aaatgatccg tacgattgat gatccgagtg
     1981 tagcgtatgc gtttgttgat gaaggctgtt atggagaaaa gggcttagac agcgtgagat
     2041 cgggtatgaa aaaagaggct attctttttt atctagactc tgttggggca gatacaccgc
     2101 tacagttttc gggaaattat ttttcaaata aagaacagtg gctgaaacaa gttgataagt
     2161 tgaaagaaaa aaacgtcaat tatattttta gtgcaagaaa aaagcaagcg cagttcttct
     2221 atttgaccaa aacagattta cgagggaaaa catttaattg gcaaaatgcc aatcagatta
     2281 ttgctctttt tcgataagta aaaagtgcaa aacaaggagt gagaagacta atgttggaaa
     2341 tcatgatcgt tacacatggt aagttgagcg aaggactgaa agatgcggcg gaagtaattg
     2401 tcgggacatc gagccatatt gaaacaatgt gcttagagtc tggggaggac atccaaacat
     2461 tcggagagaa ggtcaaagaa aaattaacta tgatcaacac agcagaaccc atgctagtat
     2521 ttgttgatct aattagcgca agtccgtaca atcaagcgct cttggcagtc aatgaactga
     2581 ctgaagaaaa gaaagcagcc acttatgtca tagggggcgt gaatctgcca atgttgttag
     2641 aagcaatcaa tcatcagatg cttcacacac cgatagaaga agcggtggaa caaattgtca
     2701 aacaaggaaa agataattta actgtttggc atgcttcagc ggaagaaaaa aaattagatg
     2761 aggacgattt ttagaaggaa ggctgaaaag atgaagtggg gatttagatg gtatggtgaa
     2821 aaaggggatt cgatcccatt aaaatatgtt cgccaaatac cgggaataaa tgggataatt
     2881 ggaactttgc tgactaaaat gcctggagat gtttgggaga tttcagaaat tgaggagttg
     2941 aaagcatctg ttgagagcca aggactggaa ctgcttggaa ttgaaagtgt agcgatccac
     3001 gatgcaatca aggcagggac agatgaacga gattactata ttgataacta tatacgaaca
     3061 atcaaaaact tgtctcgatg tggggttcga ttgatttgtt atagcttcaa accaattttt
     3121 ggatgggcga aaactgattt gtttaatgaa aacaacgatg gaagctattc tcttttatac
     3181 gatcagaaaa tcgtcgatca gatggagcca ggagaaatgt atcaattgat acacagccag
     3241 tcaaagggat tcaaattgcc gggttgggaa gaagaacggt tgaaaaaatt cgctcagctg
     3301 gaaaaactgt atgaaggaat gaccgaagaa gaattatttg aaaatctgac ttatttttta
     3361 gaaaaagtga ttccagtgtg cgaaaaagca gatgtaaaaa tggctatcca tccagatgat
     3421 ccgccatggg aactttttgg ttttcctaga gtgacgaaaa atcttggcga cttgaagaaa
     3481 attctaaatg cagtagattc tccatataat ggactaacgc tgtgcacagg atctttaggg
     3541 gcaaatccgg aaaacgattt agttgaaatc atccatgagg taggttcgcg catccatttt
     3601 gtccacttca gaaacgtgga gtttttagga gaaagaaagt tcaaagaaac ggcacatccc
     3661 tctacagaag gctcccttga tatgtatcat attatgaaag cgttggtgca agaagggttc
     3721 gacggtccta tacgccctga tcatggtaga accgtgtggg gtgaagtggc tatgcctgga
     3781 tatggcctgt atgatcgtgc aatgggactc acttacatgc aaggtctata tgaggcgata
     3841 agtaaggaaa aaccactggg agagcattat gaataaaatc aagctcttca tctttgatat
     3901 ggatggcctt ttattagaaa ctggacgttt agcttatcgt gcttatgtaa aatcagcaca
     3961 aaagtatgat tatgaaatgc gtaaggaagt ctattattta ctaactggcc aaacagaaat
     4021 ggcgataaga gaacaaatgg gcattttgta cggagaagat gttccatata tcaaatggcg
     4081 agaagcaatc aatcaatata aagaaaaaat cgtgaaagaa gataagagag tatatacgaa
     4141 aaaaggagca gaagaaattt tatcttttgc aaaagaaaga ggaatccata caatcgtggc
     4201 ttcgtctaat acacgggtaa aagtagaaat gtatttaaaa atggaaaatc tatatgcctt
     4261 gtttgatcaa atcatttcag gggatgatgt aaaaaaagga aagccggaac cagagatctt
     4321 tttgaaagct tgttcaaaaa tgaatattcc tccaagtgaa gcacttgtat ttgaagactc
     4381 gattgcaggg atcgaagcag caaggcgagc gggcattttg tcttttctca tcaaagatca
     4441 tttgataggg ttgcccgatc ataatgggaa gcataagttg aaagtagatg taagtttata
     4501 tgaatccaat aaagcagact atgaatttta tgacctgcat caagcaaaac gatttttaga
     4561 aagtaaaggg ttgtatctct aataaagagg actattttct agtcctcttt atttattgtc
     4621 ctgcacgact gagggaacag atgaaaaaga agtaattttt tattttgaag tatctacctt
     4681 atttgtagtg aacaatttag aacaaacaca aaacgcatct actgttatct accagtagat
     4741 gcgtttaaag agaagaacga gaatcgtcca tatgagggtt tccactcctt atgcagattt
     4801 ttttaattct tgcactgctt gttcgatcgt aacacctgtc gctacatgat tggtattttc
     4861 tttgtcaaaa acgacaaata gattcaaatc tgtatccaag gttactcgat attgtatatc
     4921 tttgttatag aatgtcatag ccattctcct ttctttaaat acttgctgaa aggcaacgaa
     4981 cgcgttgata acgaaattcc atttataagt ataccaccaa ttgaaaggtt ttcatagtta
     5041 agaaatttta aagtcaaaag ttgcagataa aagcaaataa acaagaaaac aaaaagtgaa
     5101 tcaatcgcgg ttattcaact ttttcttcga ttcgaagaca atagaagaca atgaatttta
     5161 tatttcattg cattatcctt gtgttattag aaaaagcatg atatattaaa tgagtaatct
     5221 attttgaaac gtaatttgag cgatatatct acatagataa aactcctttt gcctatcaaa
     5281 tatttattgc aacgaaaaaa cgtacattga tacgtatcag gaggaattta tttatgaata
     5341 acggtacagt aaaatggttc aacgcagaca aaggttttgg ctttatcact ggtgaagatg
     5401 gaaatgatgt atttgcacat ttttcagcta tccaaggtga cggcttcaaa actttagaag
     5461 aaggccaagc agtgtcttac gatgttgaag atggtcaacg tggccctcaa gcaacaaaca
     5521 ttgttaaagc ttaataaaaa ttgactttta accgtctttt cgaaagaaaa gacggttttt
     5581 ttgtacgaaa aaattcattg gtcgttgaat gggctgaata gtagtgtata aaacaatttt
     5641 gtggagcgtg aagcttttat ggtagaggaa aatacgaata aagtgatgtt gataaaaaga
     5701 ttcctatctt gaatatgaat cgagatgtct tgaaaatgaa tgagtttgac caatcattat
     5761 cctatcgaaa tttacagttt cgttcgattg gtctgtcaat taatgaaaaa gtaaaaaaga
     5821 atatgttcta ggaagagggc ggcacatcta aatttttaag taacggacag ttcaaatatc
     5881 aagcattgaa agaggctatc ctactgtttg aaggaatacg aatatataaa aacgacaaag
     5941 aggaaaaagt agttcattaa atcccttcaa gtgatgaaag aatgagatct aataaaacct
     6001 gatctttcat ctgttttttt aataacgtaa taattttttt attttttgtg ctttcgccgt
     6061 tattgtagag tgatttagca ttcttatttt taaaaataac tgtgttatat attaaaaaag
     6121 gcataatagt tataagcttt tttaaagaat atttagaaat tattaatttt cgtctgaaaa
     6181 caaaaaaaga aagcgttatt attttagtct attttcaggg ggggaacctt atgataaaaa
     6241 aactattttt actatcaata ttaacgctag caatggcagg ttgttctgac tctggcttag
     6301 caactgaact gatcacaaaa tcaactgaag ccacgacaga ggagttaaaa tgtggaaacg
     6361 atcacagtga ctacagaggc ttaaatcgac gatgcatggg aatattaggc agaagcaatt
     6421 gtaagcatcg atgtagtaat cgaagaaggt gtagaagaag caacagaaaa atcaaaagaa
     6481 agatcaaaag aagcaatctg tgctgtgcat cgtatacaga cgtcgaagat gcggtacttt
     6541 taaaccacgt caggagatgt tcatttatgt ctagggaagt tggcgatgaa ccaaaactag
     6601 agtacgcttt tagttttgca cgtgaggatg aagataaccc taaaacttac gacattttag
     6661 cttgatctaa gatggttaaa gctttttaat gaagtaagag gagatagaag gcttttctag
     6721 ttatattagg taagataaat tcctttttgc tccaaatttg ctaaacattc tgctagataa
     6781 acttcatcgt gttccggata aatcggcacg ttgcgctcta cagtaggtaa atcaaaaaat
     6841 gcttcgcatg atttgccacg atacatagga tttttccact ctggtgctgg gctgtaacca
     6901 cgtttttcca tttcatccat gacaagctga tgatattgga ataatctata aggagaatag
     6961 tgaaaaacat aatccacagt agcatgtttc tttccccagc catttcctct taatgcacag
     7021 cattcccgat gttgtcctaa aagctgttga cgaggaagct ttgaaatcaa tttttcatgc
     7081 cataatcgca tagaaatgtc tcctttatat atagattgtt aaccttagac gttaaatgaa
     7141 aaaaccagca ccaaggctgg aaaaaatcac ttcagtttgc ttgctgtttc tgagcgacca
     7201 attaggtaat caacggaaat atcgtaaaag tcagcgatat agattaattc aatgatgctt
     7261 ggaatttctt ctccttcttc gtacttacga tatttgaata aaggaatact taacgcgcta
     7321 gaaacagcta cttgagataa agatcggcca gttcttaaga aattcagacg acaacgtaaa
     7381 gtatccagta aaatagcttc ttcgatactc atttaatcac ctttcattat agtagaatag
     7441 ttataatgac tatagaaagc tacacatgca atcaatagta ctcaatgttt tttatttaaa
     7501 cgtatcaaat aaagaatgac gatcaataaa gacaaaacca gtcctgataa ttcttctata
     7561 aaaacactat cgggttcaaa gtagttgtaa ttaaaaactt tccacataaa gtagatagcc
     7621 ggaagagtca aaatagctaa ataaaaccgt tctttgttcc aattcataag ataaacaata
     7681 cttgcgacca gtgcgaccgc aggcacccaa aacaaaactc tcaccaacgt aatcatgtaa
     7741 cggactcctc aacgattcat ataataaaag ataacatgtt attgcataca tcacaaatga
     7801 aatgctagga aaataaaaga agaatagatc aatgaaaaat gaaaaagcag aacagttttc
     7861 tgctgataag caggaactgt tccgctgaat gtgtcttatc tatcgagaaa aaatcaatgg
     7921 attgatatct aagtaattca atacatataa aaagaggacg atcgcattca ctaaaaagga
     7981 aagaatgatg atcccatagc gaatggaaac atatttaaca aatacttttg tttgaatacg
     8041 ggcatatctt tttcctttat agctgagcat catgacaaga agcaaaaggg taatcacacc
     8101 ttgaaaaatc attccaataa acagaattcc tgaggtttga taatttaatt ggagaaaata
     8161 agctgctgcc gcaactaaat cgaataaaat cgcaataaat ggcaaaataa tcactcctaa
     8221 cattgagaat aaataaaaga ataacatttt ttctaaaata agcaaataaa aattaaagta
     8281 acaaaatagt tatgacacaa gtaaaagaaa taagaataac aatattattt tacttatatt
     8341 ttgaaacttg tgagagtttg tcattcgtgc tatagttgaa aagtaacaaa aataaatttt
     8401 atttatgatg tacctttagc tcagttggtt agagcagacg gctcataacc gtccggtcgt
     8461 aggttcgagt cctacaaggt acataagagg ttgtgaaaaa gctgccctgc atcaagtaat
     8521 aagaacagcc aagtaaaaac agcttcttat gtttttactt ggctgttctt attactgcag
     8581 atgcaagctt ttgaataccg tttaaggaag aggttgtgaa atcagcgttt tgacctgagt
     8641 attagcttaa caaacggaaa aatagttcct catattttgc cgtttgttaa gctaataccg
     8701 agggtcagct gattgaacac catttaagaa agaggtcgtg agcctgccgt ttcactctgt
     8761 gtcataaaaa agccaatcta ctttgataga aaaagcacgt aggactaaaa cagttctgcg
     8821 tgcttttttt attgtgtgtt aaatatcgta aatgaagata gatattttta tgattcgacg
     8881 atagagacgt tgaaatcttt caacagctct aaagcggatt ctccgtgttt tctactggag
     8941 actaacattg gatcaacaaa aaagtctgct tcaggaaaag cactctgcag gcctatcaga
     9001 ttagagagta cacacaagtt tgtttcaatc ccgactactt cgatctcttt ttgttcttct
     9061 ttgctttcaa ataaagtttc ctggatttca gctaaagttt caggtggaat cgtaaagtaa
     9121 tactttttaa tcactcgttc attttcttgt ggagaaagaa gagggatcaa ttgcaaatct
     9181 tctcgttctt cttctttgtc cttcagttca actggtatat cccgtgtgaa gagaatatat
     9241 tcattatttt ggcgtgcttt agctaatctt tgagcaatac gttctgccaa ttgatctgac
     9301 tctggaatat aaaattcgct gtttggatca agaatatgat tttgcatatc aataataact
     9361 aacattttct ttcctcctac attcatatcg tcattttatt ctttttaata gaagtttttt
     9421 aaaatataag caacaccagc ttcttcattc gtcagtgtta cttggtttgc aatttctttt
     9481 acttgtcgct gtgcattccc catcgcaata ctcaacccgc tgtaattcaa catagcaatg
     9541 tcgttttctt gatcgccaaa agccatgatg tcactcgatt cgattccaag gtaatccgcc
     9601 agaaaaacaa gtgaatgagc tttagtgata cctgtaggcg tgatttctaa gaaatgcgga
     9661 tcagagaata ctgattggat accatctgct tgcagatctc tttgtagctt ctgtagtttt
     9721 tcttcactct tatctgttaa tgctaattta agatagctaa gagaaggatc ttccaacata
     9781 tttaaaattt gatcaaaaga atggttctgt aaattgaaat gttcataata agggtcatct
     9841 ttgactagat ttgattcatc gaatgtcagc tgatcatctt gggtttctcg gctagcaatg
     9901 atggatattt tcgcttcttg agcatagaag aaggcttttc tcagtgtatc gctatctatt
     9961 tttgaacgtc tgagaacttt cgccattttt ccatccttca tttcagcaat cagtgaacca
    10021 ttggaagaaa tcaaatagcc accgattcct aattcggaaa aaatatcttt agcagaaatg
    10081 ctgttccttc cggtagcgac ggttacgatt ccgccatttt catcaaattt ccgaagtgct
    10141 tggatatttt cttctggtat ctttccattt cgatcaagca aggtaccgtc taaatcaatc
    10201 gctgctagtt tcattttatc ttcctacttt ctttttacat atctattttc ctgttacctt
    10261 aagattaaat gagaatttaa aaaaatgaaa ctaacttgct ttgtcattat gaattttttc
    10321 aaaaaacatt cttaagaaaa aggtggctat atatagtagt ttttggtcaa tacctttgaa
    10381 taaaaagcca tgaaaaacga atagttagcg cttaccgatg cgttttgtga taaaaaaatt
    10441 ttaaaatatt caatgaaaac aaagcatata ttttgcttta aaaccaaatg aggaatattc
    10501 tagatgtaga acaggttaga aaaagattag aaaaaggagt gattttgatg gagaagagat
    10561 acggcgtagt tcctgtggta actgcttcag acgaaaatta tgctccttac ttgagcgtga
    10621 tgatcgcaac tgcattagaa aattgcaata aaacaagacg cataaaattt tatgtgattg
    10681 acgatggtct atcagaatat agtaaagaag gattggaaga aacggtaaat aaatattcaa
    10741 gtaatgcaag tatccaattc ctgacagtgg aaaaagatat ctacgaagac ttcctagtca
    10801 gtgaccatat cacaactacc gcttacttaa gaatttcttt accaaactta ttagctaaag
    10861 aggattataa gaaagtcctt tacttagatt cagatgtgtt agtactagac gatatcgtaa
    10921 aactatatga tgagccgtta aatggaaaaa caatcggcgc tattatcgat ccaggccaag
    10981 tgaaagcttt ggaaagatta ggaatcgatt ccgatgactt gtacttcaat tcaggagtga
    11041 tggtgattga cattgatcaa tggaataaaa aagaaattac agaaaaaact atccattacc
    11101 tcagtgaaaa tggcgatcga atcatctatc acgaccaaga tgctttgaat gctgtacttt
    11161 atgaagattg ggaacaactt catccaaaat ggaacatgca gacttcgctg atttttgaac
    11221 gtcatccagc accaaatgaa aaatatgaac gtcagtataa agaaggaaat gaaaaacctt
    11281 cgatcgttca ctttacagga catgataaac cttggaatac gttgaaagat catccgtata
    11341 ccaatttata cttaaaaaaa ttagcacaca gtactctaac gaaagtaggc gagatcaatg
    11401 aataaaaaag aaatagcagt agtcgcaagt tgtaacacaa aattcgtacc acatttagct
    11461 gcattatttg tctcagtatt agataattgc aacccgtcta aatttgttcg gttctatgtg
    11521 attgacgatg atatcgattt tgaaagtaaa cagcttttac gcttctcagt gaaaaacgca
    11581 cgaatgaact cagatgtgga attcttgaaa atcaataaag aattctttac aaatgtggta
    11641 atcagcgatc gtattccaga aacagcttat tatcgtattg cgattccgga attgttccgc
    11701 ggcacagaag ttgaacgtat cttatatatg gattgcgaca tgatcgcttt acaagatatc
    11761 tctaaattat ggcgtcttga cttcggtgat tcaatcgtag cagctgttga agacgctggg
    11821 ttccatcaac gactggaaaa aatgaaaatt tcagctaaat caatgcgtta tttcaactca
    11881 ggtttgatgc tgatcaatgt gaaaaaatgg ttagatgaaa atattacgca aaaagtatta
    11941 gatttcatcg aacataatcc agaaaaatta cgattccatg accaagatgc attaaatgct
    12001 atcttacatg accgttggtt accacttcat ccgcgttgga atgcacaagg ctatatcatg
    12061 gcaaaagcaa aaaaacatcc aacagcagca ggtgaacgtg aatacgaaga aactcgcaac
    12121 aatccttaca ttatccattt ttcaggacat gtgaaaccgt ggagcaagga ttttgaaggg
    12181 ccaacgaaga aatattacga aaaatatgca gggatgacgg ctttccgttg tgtagctaaa
    12241 ttccctaaat atccaaaata tgcaaaagtt caaccaaaaa cagatgtagt tgttaaataa
    12301 tagaagacaa caactgaaga gggggagtag gaatggaaat tacaatgtct aaaaatgcag
    12361 tagagacgtt aattgaaaag gttggggaaa atacaaaaat cgcactcgcg cttatcaatg
    12421 attccgatcc atttctaagg gacaaaggtg cttttgcaaa aggcagcttt tttcaaatca
    12481 ttccttttgt ttcggaattt ggagaatatg cgactaaaat cgagcatcca ttattggaca
    12541 tctatacatc taaattagag caaaattatt tcggtaaacg attgaacatg gacttcaaca
    12601 aacagcttga cagcttttca ttagaaaatg aaatcgcagt actcgattat aatatcaaat
    12661 taaagaactg cttcttcagc taatagtttc gagaaagtcc aaaaaggagg tatacattga
    12721 gatactactt tgtggatgaa gaaaagaatg taatagaaac agatgaaaaa aaatataatt
    12781 ggctcgtact tgatagtgca aagcccgaag agattgagca agcaatcgaa gaattcgagc
    12841 ttcctgatga tattttcgta ggaaccgaat atccggaaga agtttctcgg atggagcgcc
    12901 tttatgagac gaaactagag catccatttt ctttggtagt gattaatcta gatcagtcag
    12961 ataatcgtat cgaaaaaaaa ttaacgccaa tatcttttgt actttccgat aatctcttga
    13021 ttacttgtat cgatagaaaa accgaatttg tggatcggct gctgacaaag catggaaatc
    13081 atttaaactc gtttgaaaag atcatcacgt atacattatt agatatttac acccattacg
    13141 tgaaagaact aagagagatg aaaaagcgaa ttgacgcttt ggataaagca gctcgtaaaa
    13201 caacggaaaa tgaagaactg tataaacagg cagatcttga aagagacatc gtatatatcg
    13261 atcatacctt aagagatcaa cgggaaacaa tggatcaatt atggaattct gaaactttca
    13321 tcaaacgttt agacgatgaa cagctactct atgatgtcca tttgagacag cgacaaacag
    13381 aaaaaatgat cgagatctat cgagatttat tagagagtat tggtgatcta ttcaacggga
    13441 tgatggacaa taatctaaat catatcatga aatatctaga ttcagctgca ttaatcattt
    13501 ccgttccggc gttgttcgca gggatttggg gaatgaatac aggaggatta ccgggtaaaa
    13561 gttctgctct aggctttata ctcgtagtct ttggctcttt gatagcagca gtagttttag
    13621 gttaccattt ataccggaaa gattatacaa attaaagaat ctatttaaaa caggtatcaa
    13681 acaaagaaat ttgttttggc aatacaattt aaaaactagg aggaatacag caatgacaga
    13741 accaaaatta atcgacccgc gaaacttgta ccatacggag aaatttccta aacaagatca
    13801 ggatacacca gctttacagc agaatatgat tcctgttcct gattgtggag aagaatccta
    13861 tgaaggcaat aatcaactag aaaaccgccg tgtactaatc actggtggag attcagggat
    13921 cggtcgtgca gcagcgattg catttgctag agaaggggca gatatcgctc ttcaattctt
    13981 cccaggagaa gaaaaagatg cagaggaagt agcaaaatac gtgaaagatg caggacgtaa
    14041 gattgtctta ctaccttttg atcttcgtga cgaacaagca cctaaagaaa tcatagataa
    14101 agccgtgagt gaacttggcg ggctagatac gatggtacta aacgcaggac agcaaatttc
    14161 ttgtcagtct attgctgagt taccacttga gcaagtcaaa gacacattta tgataaacat
    14221 catcgctatg tttgctttag tgaaagaagc tgttccgcat atcccagcag gaggagcaat
    14281 cgtaacaaca acttctgttc aagcattcaa tccaagcgaa catttattag attacgcagc
    14341 aacaaaagct tcaatcgcta actttacgat cggtttagca aaacagcttg cacctaaagg
    14401 aatccgtgta aatggtgtag cacctggtcc aatctggaca ccattacaac tagacgaagg
    14461 acaaccttct gattcgatcc ctgaatttgg tcagcaaagt ttactagaac gtgcaggtca
    14521 gccaggagaa ttagcaccag tttatgtttt cttagcatcg aataaagcaa gttatgttac
    14581 agcccaaatt tacggagtaa ctggtggaga agcgatcaac ttataagaag ttgatcgttt
    14641 cacccctatg aggaggtgcg aaaatgaata aaggtgtaaa aacgatcgga gtgatcggaa
    14701 cattactttt gctatctgtg cttttgtttg cgatactatt aagtgcaacc tatccattgc
    14761 cttttcagct agagaagttt cgattctttt ccatcactaa ttcatacgtg caacaatatg
    14821 tattttggct tgccgttgca tttgctattt tgacaattat cacgttactt gttttcctgt
    14881 tttatccaaa aacaatcgga aactttctac tgaaacatgg tgatggggag ttgacgttgg
    14941 ataaaaaagc aattgaagga atggttcgtt ctcacttgca tgaagatgaa ttcatccatt
    15001 caccaaaagt aaatgtcaaa gcaacgaaaa acaagatcgc cgtcaatgta aaaggggagt
    15061 tgaaacgaac ttcagcactc attggtaaaa caggaacatt gatgaaagaa atcgaaaatg
    15121 aagtacaaca catattggga acaaaagagc cagtgaaagt atcggtgaaa tacacaggct
    15181 ttgaagaacc agctaaacga agcaatgacc gcaaacgagt agaatagggg gggaccaaaa
    15241 atgaaagaac tattttcgac atacaagctc cctatcatct ttggggtact tggattgata
    15301 ttagccgttt tatggatcac cgtgggcttt ttcaagacct tattgatctt gatcatggca
    15361 gcgatcggcg tcgctatcgg tttttatctg aaacaaacga aaatcttaga tcactatttt
    15421 aaat
//
LOCUS       DAXQKX010000060        14851 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.062, whole genome shotgun sequence.
ACCESSION   DAXQKX010000060 DAXQKX010000000
VERSION     DAXQKX010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14851
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.062"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(361..1479)
                     /locus_tag="ACF3MF_002168"
     CDS             complement(361..1479)
                     /locus_tag="ACF3MF_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928125.1"
                     /translation="MAKKDKELLTQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            1712..1834
                     /locus_tag="ACF3MF_002169"
     CDS             1712..1834
                     /locus_tag="ACF3MF_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928126.1"
                     /translation="MHLIMIFSLLSIISLFAFSASRLLDAETQPIPVKVRKNDR"
     gene            1950..3257
                     /locus_tag="ACF3MF_002170"
     CDS             1950..3257
                     /locus_tag="ACF3MF_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008800 - beta-lactamase activity
                     [Evidence IEA];
                     GO_process: GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HFE3928127.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWGDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            3376..4575
                     /locus_tag="ACF3MF_002171"
     CDS             3376..4575
                     /locus_tag="ACF3MF_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HFE3928128.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVLLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYLAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(4602..5870)
                     /locus_tag="ACF3MF_002172"
     CDS             complement(4602..5870)
                     /locus_tag="ACF3MF_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HFE3928129.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLCLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVCRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
     regulatory      complement(5925..5991)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01734"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Fluoride riboswitches increase expression of
                     downstream genes that help mitigate the toxic effects of
                     very high levels of fluoride; They are found in a wide
                     variety of bacteria and archaea; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="fluoride"
                     /db_xref="RFAM:RF01734"
     gene            complement(6033..6679)
                     /locus_tag="ACF3MF_002173"
                     /pseudo
     CDS             complement(6033..6679)
                     /locus_tag="ACF3MF_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FusB/FusC family EF-G-binding protein"
     gene            complement(7087..7590)
                     /locus_tag="ACF3MF_002174"
     CDS             complement(7087..7590)
                     /locus_tag="ACF3MF_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFE3928130.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(7713..8477)
                     /locus_tag="ACF3MF_002175"
     CDS             complement(7713..8477)
                     /locus_tag="ACF3MF_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HFE3928131.1"
                     /translation="MKEIQSVKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLAEVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSSTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            8584..8859
                     /locus_tag="ACF3MF_002176"
     CDS             8584..8859
                     /locus_tag="ACF3MF_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HFE3928132.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            9575..10525
                     /gene="yidC"
                     /locus_tag="ACF3MF_002177"
     CDS             9575..10525
                     /gene="yidC"
                     /locus_tag="ACF3MF_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0051205 - protein insertion into membrane
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HFE3928133.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGGAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVIMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPADNKQATKQIKQPKNSTNNKGRNAGRQQKRK"
     gene            10647..11856
                     /locus_tag="ACF3MF_002178"
                     /pseudo
     CDS             10647..11856
                     /locus_tag="ACF3MF_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012008915.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            complement(11901..12301)
                     /locus_tag="ACF3MF_002179"
                     /pseudo
     CDS             complement(11901..12301)
                     /locus_tag="ACF3MF_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723846.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(12548..12982)
                     /gene="tnpA"
                     /locus_tag="ACF3MF_002180"
                     /pseudo
     CDS             complement(12548..12982)
                     /gene="tnpA"
                     /locus_tag="ACF3MF_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005576373.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(13160..13526)
                     /locus_tag="ACF3MF_002181"
                     /pseudo
     CDS             complement(13160..13526)
                     /locus_tag="ACF3MF_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387104.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            complement(13540..13825)
                     /locus_tag="ACF3MF_002182"
                     /pseudo
     CDS             complement(13540..13825)
                     /locus_tag="ACF3MF_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311319.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
     gene            complement(13834..14025)
                     /locus_tag="ACF3MF_002183"
                     /pseudo
     CDS             complement(13834..14025)
                     /locus_tag="ACF3MF_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018659219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(14025..14501)
                     /locus_tag="ACF3MF_002184"
                     /pseudo
     CDS             complement(14025..14501)
                     /locus_tag="ACF3MF_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290865.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
     gene            complement(14595..>14851)
                     /locus_tag="ACF3MF_002185"
     CDS             complement(14595..>14851)
                     /locus_tag="ACF3MF_002185"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928134.1"
                     /translation="CTLWLSNDLIIITFRVIYVLQKNKRLEKTTDERIQNHLYQRRGR
                     RRGGRMWLHGYDGYDAVRNFLEFACGILKILRVRFIRRVD"
BASE COUNT         4438 a         3102 c         2660 g         4651 t
ORIGIN      
        1 acggtgttcc agaagtagct tcttcggaaa taagccgaaa tttcacaaaa atttgagaaa
       61 taatttttgt caatctcttc ttatttcttg aagctgacca cttctgtcac aacctcttcc
      121 ttaaacggtg ttcaaaagct tgcatctgcg gtaataagcc caccaaacaa aaaatatgaa
      181 gagctatttt tgcttgctgt tcttattact tgatgcagaa cagctttttc acaacctctc
      241 atacacggtg tttaatcagc tgaccttcgg tattagctca aaaaacggaa aaatatgtga
      301 aactattttt ccgtttgttt ctctaatact caggtcaaaa cactgatttc acaacctctt
      361 ttaataacga agaatcgctg tcagactctt ttcatctggc gcatcttttt gatccaaaat
      421 aaacactttc ccgccattaa tgatcacatc atctgctaat gcattcaaca cttgacgccg
      481 atcatattct gtttcaggat cttcaccgaa accatcagct aagtttgacg tagcgataaa
      541 taaatgtgac acttttcctt ctttcgcagc tggaacgata tcaactaact gatcgatgaa
      601 tttcttatct aagagtttat tgtattcttt tgattcttga gctgcgagtt cacttgacag
      661 cttcttcgcc ccttcttcga tatctctaaa ggatagctgc gcaggagaag cagaaatcgc
      721 aacgtctgca caataatagg gatttttagc aatttttttg aacatcgtct gattttctgg
      781 taatgcaaat aaataaatcg gccattgttc aggattttcg aaagaatcct tcaagtacgt
      841 atcaacagct tggtaatagt tgacccaatc gatctctact tcttcatctt ttggatttac
      901 gccatggaaa gttactccat ctcgggctcc gcctcctcca ttagaagaga agttcaaacc
      961 gccacctgtc agttcagatc ccaatgcagt aacgacatca accggtgccc cttctggtag
     1021 agatacttct tttacttgtt tgttgctgac ctcatacaat ttcatggagt cgcggttcaa
     1081 tcccaataaa taataagaat agttgaactg cccatttttg ataatagcca gtaaataagg
     1141 aagatcactt acatagtatt gatcgtctac cgggatactc aaacgatgga tataggtctg
     1201 gtcagcagtt ataatgaccg ctacactcgt agttgcacta cgccaaaacg aaggatctcc
     1261 taacaaattt tcaatttttt cttggaacgg ggaccagtca tgttcggaat attttttctc
     1321 aaaacgtttc tttgcttctt tcgcaaaatt tttgaatttg atctgatctt tttccacatc
     1381 ttgatgggcg acatgcgtat tcagcatgat cgtgacgaat ggtcctttag cgccttctga
     1441 agtcaattgt gtcaataatt ctttatcctt ttttgccata aacgtacccc tcctaaaaaa
     1501 atcattcctt tgtttctatc taaagtctac cacaacacta tttttccata caataaaacg
     1561 tatctaaaaa aataaaacgg tttctacggt tttaaattta gctatttttt taagttatct
     1621 tcataatttc ctcaattatt tagccccagt cttcaactat tcttcatgaa atgctgataa
     1681 actaagaaaa agaataaaag aggtggatct tatgcatttg attatgattt tcagtttatt
     1741 aagtattatc agtttatttg ctttcagcgc ttcccgctta ttagatgcgg aaacacagcc
     1801 tattcctgta aaagtacgta aaaacgaccg ctaaacttcc ataacgcgcg ttcttatcct
     1861 aaagtttttt cagaaacatt gaaactctct cccctctctg ataaaatttt aatttgtagc
     1921 gaaacaaatt aattacaagg agatcggata tgtccataaa aaaaacacgt ctagtcctat
     1981 tattggctag tctcattctt tgccttgctt cttttctacc agctgttgct gtgcaagctg
     2041 aagatacgtt caaagtaaat gcaaaagcag cttttgctgt agatgcgcaa agcggtaaga
     2101 ttctttatga tcaagatgga gaaaaaacca tggggatcgc ttcaatcaca aaaatcatcg
     2161 gtctttacat cgtccttgat caagtaaaag aaggaaaact gtcatggggt gataaagttt
     2221 cgatttcaga ttatgcagaa aatttgagta tcaccccaga tttatcgaat gttcctttgc
     2281 ataaagaaaa cacctacact gtcaaagaat tattcgactc tgcaatcatc cagtcagcca
     2341 atgcttcaat ggtggccttg gcagaaaaaa tctctggcag cgaagctaaa ttcactgaac
     2401 gaatgaaaga acaattgaaa gattggggaa tcaaagatgc aacaatcgtt aatgcatcag
     2461 gattgaacaa ctcttatctt ggcgaaaacc gaccagaagg cactggagaa aacgacgaaa
     2521 atcaaatgtc tgctcaagat gtggccatcg ttgcccgcca tttgatcttg gatttcccag
     2581 aaatactgga tgtatcaagt actacgaccc aaatgtttgg cgaaaatacg caatcaccag
     2641 tggaaatggt caactggaac tggatgctcc caggattcgt taattacaag gaaggcgtgg
     2701 acggattaaa aactggtacg actgagcttg caggtgcttg tttcgttggt acgatcacta
     2761 aaaacgatca acggatcatc actgtcgtat tgaatgcgga cggccatgcg gaaaacccga
     2821 gtgcccgctt caatgaaaca gaccgtttga tggactactg ctatgacaat tggtcagaaa
     2881 aagagctcgg aaaagctaac gcaagtattc ctagtctaaa aaccattgat gtaaaagacg
     2941 gaaaagaatc aacagttcct gttgtgctta aaagccctgt aaaagtatgg gtacgaaacg
     3001 atatggatac tggcaaatta acgatcacgc caacacttga caagaagcaa gtcactgaca
     3061 atgagatcca agcacctatg gataaaggta caaaaatcgg taccgctacg atcaccttgg
     3121 cagacgataa attaggctat ttagaagaca acaatgcacc atcaacagag atcattacgg
     3181 ataaaacagt ggaaaaagcg aatatattcg tgattggctg gcgacgcgtc gcagaatttt
     3241 tcggcaactt gttttaattg aacaataaga aaaacatctt tccatcggaa agatgttttt
     3301 ttgctttttc tagtttaaat aacagctttt ttcatctatt ttcgttatac tgtataagaa
     3361 aaaggagttg aatttatgaa tctaaccaga gatctgatct ttttagttct ctatcttatt
     3421 ggggtattct ctatcgttta ttggcgaaaa cagaagaagg atccttcctt gttcttttac
     3481 ggcagtacgt ggacatttac ggtaatctta acttattttg tcgtgttgga aattttttat
     3541 tcgacctttt attttttgat tccattgttg ttctttagta tctttgcttt ttcttatttc
     3601 acagaaaaac gaaggctact gaatggtctt ttattcaatg ttttactcat cagtttcggc
     3661 atctacttgt ttgtcttgct gtatgaaacg caaaatattt ttcttggcgg actgatcgcc
     3721 ttgatcacga ttccattgct acttgtcctt ttatttggta tttatggatt gattgttttt
     3781 cttttttgga acggggtcac agttttacgt agagaatcgc attcattagc taatctttta
     3841 acgttgatac tagccatttt tcttacactg tttcttgttt ttgacttttt cttgttaaaa
     3901 tatttgccgc aatggataaa tgctttgttt ttctgcgttc ccctgatctt gatctatcta
     3961 tttatcgtat tctacaactt tttgactgtc tcattcttgt atcagttcaa ccggcctcga
     4021 tacaatcaag acttcatcgt tgtgttaggc gctggattga tcaatggaga aacagtttct
     4081 cctcttctag ccaagcgaat caataaggca attgcttttt atcgggctca aagccgtgct
     4141 acattaaatc cgcccatctt attgatgtct ggcgggcaag gagcagacga aaaagtacca
     4201 gaggccattg cgatgaaaca atatgccatg gaacaaggaa tccctgaaag agacattctt
     4261 gtcgaaacca attcgacaac cactttggaa aacatgctct attcaaagga aatcatggat
     4321 cagcaaatga aagggccata ccgcgcgatc tttagttcca acaattacca catttttaga
     4381 gccggtcttt atgcgcggca agccaaattg aaagcaaatg gtattggtgc aaaaacagct
     4441 ttctactact tgcctaatgc gtttttaaga gaatacctcg ccatcttgat gatgaacaaa
     4501 aaaagacata tgatcatttg cggattgctt ttcgcaggct ccgcattctt atcgctgatt
     4561 actttacttt tctaaaaaaa caaggtgtga caaaacatat gtcacacctt gtttttttct
     4621 ttcattctct taactattgg caaaaagagt atcccttttt tgaccgctac ttgctgagca
     4681 gaataaatac cgctgttgcc tgaacacata aagctgatca agcagatcat aaagaagtat
     4741 actgccgctt gtgaaccgaa caattcgatc cccatcacaa agcaggcaat cggtgtattt
     4801 gtcgcaccag aaaatactcc gataaagccc aatcctgcaa gaaaaggaac agaaacatgg
     4861 agcaaaggcg ctagtgctgc accaagcgtt gcaccaattt caaacaatgg tgtcacttct
     4921 cccccttgat atcccgcgcc taaagacaaa actgtgaaga ataacttccc aataaaatca
     4981 tagacatgtg cctgtccatt aaatgattct tgaagtaacg gaagactcaa tccgagataa
     5041 cgttgtgttt gcaaaatcaa tgctgctgcc acaactacag ctccacctat cgtatttcga
     5101 caaacaggat gaggaatcca ttgtgcatat cgcgctttta aaaagacgat cgaacggctg
     5161 aatacccaac caatcaaacc aaaagcaatc ccagcaacaa aaactttgaa gaacagcaac
     5221 atactccatt caggaatcac acccatttgg taatgtagat gagaaacacc atagctttct
     5281 gtcatgaaat ttgcaaacag tgcagcaaag aagctaggga agatcgcttc tgttcggact
     5341 ttcccgattg ccaacacttc taatccaaat aatgttccag ctaaaggtgt gccaaataca
     5401 gaactaaaac ccgcactgat tccactgata atcaagattt cccgttctga tttatccaat
     5461 cggaacaaac gtgccgtatt atctgctaac gctcccccca tttggactgc tgttccttca
     5521 cggccaacag atcccccaaa taaatgggta gttatggttc caaacagtgt aagtggaata
     5581 agccgcaacg ggattttttc ttctccacca tttccttgat cgatcactaa gttgtttcca
     5641 cgactagaaa gtccgccgtg atacgcatag agataagcaa aaagcgcacc actaactggt
     5701 agtagacaaa ggagccaagg atgtgatagt cggatatctg tcacaactgt caggctattt
     5761 aagaaaaaag cagacaagct ccccatgaat ataccgagaa tcgctgtgat caccagccac
     5821 ttcagcatat acactaaaat gcgtactgga ctcggtaatt gtttttccat aaaaaattcc
     5881 tcctcaataa aaaaacgcct actaaagaaa ggggctgtcc ccagacttta gtaggcgtca
     5941 ttagctatct ttcgttagca tttaaaggcg aacaccatca cctattcact tccattaaaa
     6001 gatagcatat ttttctgtaa aaaacaataa aattatcgtt ctttctttac acgttcagca
     6061 aattcataga aaggagccaa tttcgttaac tgttgattac attggtcact atcatgacaa
     6121 atataattcc cctttttcgt atacgtgcca tcagaacctg ctttcgttgt agaaagaaaa
     6181 agcgaaacat tcgatgtttt ctgacagatt gcacagattc ccttatttat cgttggtgat
     6241 aaagtaccgc taatcccttt taatttttca tcttcgtaat agaccatgaa ttttttctgc
     6301 gtacctggat cattccagcc gatgtacgta tgttcttgca agtcgatttc attccaagct
     6361 ggttgtttga gttttttcac ttttcggaat aatttctcga tttgtggttt gctaggctgc
     6421 ataaacggct gaacgatttg cttcagctcc tccaatgctc tttctgcttg cgcttttgtc
     6481 agttttacgt ctaaaactgt cgttaaaaat gtatcgattc tggcagttcg tgatctaata
     6541 tgtctcgaat cttttcagct gctagtgcct gaactgtttg taccgttttt ggatcattga
     6601 cagatgagta cgcatttaat aactgttcta cttctcttat tataaaaaaa tattggtatg
     6661 gttttattgt ttgttccatg attttaaagt cctttcttct aaccaaagtg catactttgt
     6721 agaaaaaagt gatcttctgc aaagtatgtg ttacctgaag atcctggact cttttaaata
     6781 agatacgttt tgcatcttat catcaccccc tttaatgctt attattctat gtacatgatt
     6841 cattcgataa ataaaagtaa accgtatctt gaacagatag tcaactgcaa acagaaaaaa
     6901 ggactgtgac aaaagtcgtg tcaaagtccc ttgtttcgaa tgaatggtgt tcaaaagctt
     6961 gcatctgcgg taataagccg aaacttcaca aaaatttgag aagtaatttt cgtaaattcc
     7021 ttcttatttc ttgaagctga ccacttctgt cacaacctca atatggtcta ttattggttt
     7081 tacctgttaa atcgaggatt ctttcccaaa gtaacgttgc catctcttac gcatacttgc
     7141 agacatgggc tgagccgctt ctttgactgc gcagtatttg tccacgaatg tcacaatata
     7201 tccttcttta tacttaggcg gtgcgatcgt tgcaccccac atgtgcttca aaatgatatc
     7261 tcgctcaaga tccgacaaat cggtgatttt ttctgcattc tttacagcaa ttcttggatg
     7321 gatatacgca tgtgtcccct cgtcaaattt cgtcgtacgc caatcatagt agaacagatc
     7381 atgcaaaagt ccagcacgcg ctgttgcttt agcattgcca ccccattttt ttgcgagcag
     7441 ataactatag taagaaacac tgatggaatg ctccaaacga gtggaatgaa catgctgtgt
     7501 gtaattcgct aattttttca ctgcttctgt ttctaaaaga tcttgtacat aagacatata
     7561 ttcttcgtct tcacgccatt tttctgtcat aattatcgat ttgccacctt tttgaatttc
     7621 attttcttct gaaattgatc taagtatacc accagtgttc ggattattct agtcgctcta
     7681 gataaaatag ctaaagctta atagttcctt aatcataaag aaaaatgata aagaacgatc
     7741 cctgctgcga ctccgacatt caatgattcc gcatttcctt tcattgggat atatacgttc
     7801 tgatcagtcg aagacaagat ttcctgactt actccctgac cttcgtttcc catgattata
     7861 gcgaaatcct ctgttttttc tactttgtct aatgcatgtg cttcttcatt taattctgta
     7921 ccgtacaccg taaacccttt gcctttcatt acagggatca cttctgccaa atctttttgt
     7981 aacacaggca aatgataatt gcttccctgc atgcttcgca gcacctttgt actataaata
     8041 tctgccgttc ctttacctaa taaaacacca gccataccaa acgcatctgc cgtacggatc
     8101 atcgttccca catttccagg atcctgtaca ttatctagta aaagccagcc tcctgaaaaa
     8161 tctggcgtat cttcagatgt taacgtcatc actgctaaga tcccttgcgg tgtaggtaga
     8221 tctgacatag cggtcatgac ctcatctgaa actagaaaag tagaaatctc tttgtttaca
     8281 gccagccagt ctccccattc tttcatacct ctctgtgtca caaaaagttc ttttatttct
     8341 gcatcagacg acgcagcttc ttcgatcaga tggaaccctt ccaaaagata ttctgccttt
     8401 tcttctctgt atttcttttt atgtagtttt tttaattctt tgattcttgg attttttact
     8461 gattggatct ctttcacatt cctcacctca actgattata tcatggaata ggtgcttgag
     8521 cttgtttcat cctaaaaaaa tcggtatcat tgatttataa aacaggaaag aaaggtgacg
     8581 aacatgcgca aagttaaaat gaatgtccaa ggacgtgtcc agggcgtggg atttcgctat
     8641 atgaccaaga tggttgctga tcagttaggc gtgaccggaa cggtaaaaaa cgaagacgac
     8701 ggctcagtca caatcgaagc aatcggaaat gacgacatca tccaaaaatt tatcgaagaa
     8761 gtcaagaagt ctccgagccc aagtggacga gtgcagtatg tggatgtcca agaagatccg
     8821 atgattgagg aacgaaagaa atttgatgtg gtgggataag gttgtttttg aagcgctttg
     8881 cctcgagtat taaggagaaa cattttccaa atagcttctc atattttgaa atgtaatgac
     8941 ttaataccga gaggcagctg ataaaacacc gtcaataagg ttgtgaaaaa gctggtctgc
     9001 atcaagcatt aaggactggt tgtgaaaaat agctctccat atttttcaac aggctggact
     9061 taatgccgta gatgcaagct tttgaacatc gtcgataagg ttgcgaaaaa gctgatctgc
     9121 atcaagcatt aaggactggt tgtgaaaaag tcgcttagtt ttgagtatta aggaaaattt
     9181 tgtgaaaatg gctttccaca tttttgcata aatttgactt aataccaaga aactgacttt
     9241 tgaacatcgt cgataaggtt gtttttgagg cactttgcct caagtattaa agacaggtag
     9301 taaaaaagct gatctataac ttgcaataaa tttgcttaac ccatattttc cagacagaac
     9361 aaaaaagttt ttagtttttt aaataagaaa gaaacacttg gaatcactct tttctttcta
     9421 agtatttctt tcttgatttt ttgtcttttt tcaaaatttt tcgctacgaa aaagaacgaa
     9481 tatttatatg aaatttctat gaagttgatt gaattccatg cgctttttta gtatagttaa
     9541 gtttgtgtaa aaattataga agaggaagta ttctatgaat aaatggaaaa actggttatt
     9601 gggatccgga cttgtcagta tcctgctctt tttatctggc tgtgtgcgga tggattcaaa
     9661 cggaaaccct gacacttcag gaatcgttta tcgagtactc gtccatccta tgggccaagc
     9721 gattacatat ctagttgaga atttcaattg gtcttacggc tgggcagtta ttgcaatgac
     9781 tgtgatcgtt cgtatcatca tcttgccact aggtatcagt caatcgaaaa aaacaatgat
     9841 ccaatctgaa aaaatgcaag cgttaaaacc acaagttgaa gcagcacaac aaaagctaaa
     9901 agctgcaaca acacgtgaag aacaaatggc agcacaagca gaaatgcagc aagtatatcg
     9961 cgaaaatgga ttgagtatga ccggcggaat cggctgtctg cctctattga tccaaatgcc
    10021 gatcttctct gccttgtatt ttacggctcg ctacacagaa ggtatccgtg aatcatcttt
    10081 ttacggcatc gatctaggct caccaagtat ggtgcttgtg gccatcgcag ggggcgctta
    10141 tctgcttcaa ggatatattt caacaatcgg tattcctgaa gaacagaaaa agacgatgcg
    10201 tacgatgctg atcgtctctc ctgctatgat cgtcttcatg tcgatcagtg cgccagccgg
    10261 tgttacactt tactgggtag tcggtggtgt gttcagctgt ctgcaaacat tcatcacaaa
    10321 cgttataatg aaaccgcgtt tgaaagcaca agtggcagaa gagttgaaac aaaacccgcc
    10381 aaaacaagtc gttactccaa gaaaagacgt gacagaatca gcaaagccag ctgacaacaa
    10441 acaagcaaca aaacaaatca aacaaccaaa aaacagtaca aacaacaaag gccgcaacgc
    10501 aggaaggcag cagaagcgga aataaaaata tatgacaaaa aactgtagac aaataaaaaa
    10561 atttctttgt tctacagttt ttttgttaca attaaagaaa acgttcgcat ttcgaggagg
    10621 aatgtataat gatgtccaaa taatcaatgt atagtcgaat ggaagaagac aaaatttcgc
    10681 tagatgcact tgttcctaaa aatcatttag tccgtaaaat tgacaaatta ttgtcatttg
    10741 attttattta tctcattgtt gaatcaactt actcgaccat tggtcgccct agcgttgatc
    10801 ctgtcgtctt agtaaaatta gtattcattc aatatttatt tggaatttgt tcgatgcgtc
    10861 agaccattaa ataagttgaa acaaacctag cttatcgttg gtttcttggg cttagtttaa
    10921 ttgataaagt tcctcatttt tcaacttttg gtaaaaacta tgcacggcgt ttcagagaaa
    10981 ccgatttgtt tgaacagata tttatcatta ttctcgaata agcagttgat gctagattta
    11041 ttcatgaaga aattttgtat atggattcaa ctcatattaa agcgaatgcg aacaaacgta
    11101 tttttacaag agatatggca cataaagaag ccattttata ccaaaaacaa ttagaagaag
    11161 aaatcaatga ggcaagaatt gccgaaggca aacgtccttt tggttcaatc attcgtcagg
    11221 aggtggtcga aagaaaattt agcatcgcag atccagaaag tggttattat gtaaaaacag
    11281 aacgagaaaa acagtttgct tattctgctc ataccgttgg tgatgaaaat ggttttgtat
    11341 tagatgtcat gattacgcct ggaaatctac atgatagccg aatgctcgtg ccacaaatcg
    11401 aacgcgttaa atcacgttat ggtgtagctg ctaatgctgc gtacaaaaca ccttggaacg
    11461 tcaagtattt aatcgaacga aaactacgac ccattctccc ttatatcagt ttcgcacaac
    11521 tactcgagat ggctataaaa aatatgtatc taaatctttt atttgtgaaa gttgtccatt
    11581 attgaaaaat tgtacagaaa gccaaaaaca ccaaaaagaa atacatcgac atatttggga
    11641 agactactta gatgaagcag aacatttacg ccatacggtg tacaatcgtg aaaaatataa
    11701 aaaaagaaaa gaaacgattg aacgcatttt tgcagacgca aaggaaaaac atggaatgcg
    11761 ctacaccaag tatcgaggct tggaaaaaat caggtgcata caatgcttgt ttttgtcgca
    11821 atgaatctga aaaaattagc tacttggcag tgggagcata tgtcgttata tcttttatta
    11881 tacaaaaata gacaaaagta tcagtctaca ctcttagtaa agaggaaact gatgcttttg
    11941 tctacagtct tagagagtgg gacaatagtt ttttcttctt tacgtctttt cctctccatg
    12001 tattttccta attttcttaa tttaacgcca tgagtgccaa gccaatgtca atcttggctc
    12061 cttgtttcct tcataagtgg aaatccgttt ccgatagatc gaaccttctt tttcctctaa
    12121 aagttttttt acattctgct ttgaaataac gccatgtatt attcactaaa atttgtcggt
    12181 ttcgctcact ttttgctttc gtacattgac tacgaacagg tcagcaccga ccactttcac
    12241 attcgtaaat tttgaagaca cgtataaatc cacttttatc ttttcttcga ctaaagcgtt
    12301 gaccgcaaaa gcgacatctg tttcagaaat atattgttcc atatctaatg gtaaaatttt
    12361 ttggttgatg gtataatttt taaacataaa gcactcgctt cctttctgat tgggtttggt
    12421 cactttaatc ctacagggat gagtgctttt tgtgtacctt aaaatcagta aatatccatc
    12481 cgtgaaaacg ggtggctttt taacagccct agaagggctc accactcaca gccctatctc
    12541 tctttaacta tttaaatgga tctacatact cttgtttact tatactgtct ctaattcgat
    12601 catctgcttc ttgttctcaa atatatattt caattgtttt ttgatttaac ccaaccgtac
    12661 tcacgtagta tcctttggtc caaaagcttt tattcccata cttatatttc aaatttgcat
    12721 gtttttcatg gattaaggtt gcacttcgtc cttttaagta gcccataaaa ctagaaatac
    12781 taatctttgg cggtattctt actaacatat gaatgtgatc aggcattgca tgagcttcaa
    12841 tgatttcaac atctttcctc tcacacaatt ttcttaatat ctggccaata cttactctta
    12901 actttccata aatcactttt cgtcgatact tcggggtaaa gactatgtga tacttacaat
    12961 cccatctcgt atgtgctaaa cttttatcgc taaagctatt tcgtccacgc gtagaaacgc
    13021 gcgttttttt gtttcgtacg ctacgccaac gaaactgact aaagtcaata aaaaaagtgg
    13081 ggcaataatc agattttttt ctgactattg tcccactctc tttttattac tcttcatctt
    13141 ctactattcc actaattaat tagttgacag atacaatgct ttcacatcct gcacgaacaa
    13201 actcgggctc tgaaccaatc acttgcgagt tgataaattc aatgaccata ggaagattaa
    13261 tccgacataa agtttaatct gttgtccttc cattatcagt ttagaaatga tattagtagg
    13321 tgtaccgcct aaaagatcgc atagtaccac aaaatcattt aacgaatcta tgacagtaag
    13381 agcttttgtc tgtatgtttc agtgccatct tctggtaata aaggtaacgt gtagatattc
    13441 tcttgaggtc ccataatcat ttttgtactt tttttcaatt cctcacaaaa ttttccgtga
    13501 ctaatcaata tcaattttct actcattttt ggctctccct tatttcgaaa tcacacacaa
    13561 tgcagataaa gccacacaca agtaatacga taaaaatcgc tcgagttggg tcatattttt
    13621 ctttcctaac aaccaataaa cacctcgacg atcccagcga gtaagatttt agataatatc
    13681 atatcgatat agttttgcat attcaatgtc acatcgccaa tcgttggtac cataaaaatt
    13741 taatatcaat cattgttgca actaatgctc ctaccatgaa cactcttaat aaagtcgcta
    13801 cgtccgttaa tacagttaag cgagattaca ctagatgatc tgttcctgcc aaggcaagag
    13861 ccagaagcgg ttgcctgccc atttgccttt ggtgtgtcgg agctgtccga taaagttcac
    13921 cgcccgatcc gctctggctt tgtcgtagtg acattccgaa agcatgaatc ggcttggtgt
    13981 gtattccttt aatttgggat agccctttgg tctggtttct gccatcagct accacctccc
    14041 aacagagcct ccatcgcatc ttctgctccg acaccaccgc catcaccggc aatgatacgg
    14101 cttctggacg aaggcgtcag accgaactgc tcggaaaatc ggttcataat tttcagatag
    14161 gtctgggcaa taaacacctg tggtacctgc tgccaatagc cggatagggt tttcacgatg
    14221 ataccgtgct gggtaatgaa ttcctcggct tccttccagc gggcgtaggc ttggcactaa
    14281 ccggcaaagg cagccatatc cacatctgtc aagattccga tggcctccat ctgctttgcc
    14341 agacgcttcc attccttctt tgcctctggt tccagccact tcggacaggt cggtgccttc
    14401 ttttccggcg ttgactcttt tgcattgagt gggcgattgc ccggatttcc ctccagcttc
    14461 ttcatggctg tcggggttga ttttcttcct ctggttgcca cagtcgtcac ctcccttcaa
    14521 tgtatttctg ccagtagaca gagaacagag ccaagtcgaa acctgactct cttctctatc
    14581 tgctaacttg tatttcagtc cactcttctg atgaatcgca cccgcaggat tttcaagatg
    14641 ccgcaggcaa attccaagaa gtttctgacc gcatcataac catcgtagcc gtgtagccac
    14701 atccttccac ctcgccgccg tcctcgtcgc tgatataaat gattctgtat tcgctcatct
    14761 gttgttttct ccagtctttt gtttttttgt agtacatata tcactctaaa agtgattatt
    14821 atcaagtcgt ttgaaagcca taatgtacac a
//
LOCUS       DAXQKX010000061        14376 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.063, whole genome shotgun sequence.
ACCESSION   DAXQKX010000061 DAXQKX010000000
VERSION     DAXQKX010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14376
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.063"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..115)
                     /locus_tag="ACF3MF_002186"
     CDS             complement(<1..115)
                     /locus_tag="ACF3MF_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HFE3928135.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDR"
     gene            246..698
                     /locus_tag="ACF3MF_002187"
     CDS             246..698
                     /locus_tag="ACF3MF_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928136.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            712..1401
                     /locus_tag="ACF3MF_002188"
     CDS             712..1401
                     /locus_tag="ACF3MF_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928137.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1526..3877
                     /locus_tag="ACF3MF_002189"
     CDS             1526..3877
                     /locus_tag="ACF3MF_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase domain-containing protein"
                     /protein_id="HFE3928138.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3957..4352
                     /locus_tag="ACF3MF_002190"
     CDS             3957..4352
                     /locus_tag="ACF3MF_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928139.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4677..5294
                     /locus_tag="ACF3MF_002191"
     CDS             4677..5294
                     /locus_tag="ACF3MF_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFE3928140.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            5335..5634
                     /locus_tag="ACF3MF_002192"
     CDS             5335..5634
                     /locus_tag="ACF3MF_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HFE3928141.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            5668..5835
                     /locus_tag="ACF3MF_002193"
     CDS             5668..5835
                     /locus_tag="ACF3MF_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFE3928142.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(5880..6485)
                     /locus_tag="ACF3MF_002194"
     CDS             complement(5880..6485)
                     /locus_tag="ACF3MF_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFE3928143.1"
                     /translation="MGKIGYIRVSSQDQNLDRQLAMMEGLNIDKLFQEKASGKDTERP
                     EFQKLLNYIREGDCVIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQ
                     KRLVFKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
     gene            6610..9597
                     /locus_tag="ACF3MF_002195"
     CDS             6610..9597
                     /locus_tag="ACF3MF_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HFE3928144.1"
                     /translation="MDEIKSNKKAFGIYLGEPSTEQLNQFFYLHEKDLELMETIRRPA
                     TRLGFALQLVSLRFLGTFILDLTNIPQNVLSYVATQLNIDPGEIIYYSRRQTRYQHTK
                     LIKSHYGYQDFNQPEIETYLANWLLNRALYTTESSDMLFDMLLKKCLDEKIVLPGITT
                     FSRFVASAIEKAEEHLYRQLSLVPTEDERKRLLNHLELIGTPVYGAIIKMDILRTPLA
                     DDSHKEIARGFDRLKQFQAFSTEKWKMESIPEGKIKVLANYAFKAKAQLIQRMSEQKK
                     LALLVAFIFIYKRKAMDEQILALSNFFETVFRRAKNKESKERLRTIKDLDRAASTLSD
                     IVDLVMSSHSDTNELSLRDRILEKYSEENVTEAVSQVRLLVKNDREPIAISELLNTYR
                     KFRKFIPDILTTLTFDSNDYGNNCKELWTFINNRFPKPITYKMFGAIKHTLPKKWIYY
                     IHEYPEQTNKCVLIAAVELLIQSLKRHDIYIPQSVLYNNPMDCLIDEKTWVQQKYVLL
                     EQLDLPSSANEMSLWLKNDLELSYKEALNRWPTSKMARIENADRLVVSRLKKTYEKKE
                     DKSFRRRIQQLLPKIDLSDLLLEVNQQLNLTQSFNHLSDKDTKMKDLDISLLAVLLSE
                     SCNIGFSPVSKEGFDSLKYDRLVYVNHHYIRVDTLSGANQKIIHAHRKLATSKIWGDG
                     HMASADGIRYITPQRSLYSRSNPKYFGRGRGITFYNFVSDQYIGFHGMVVSGTLRDSL
                     YLLEGFLNQPSELTPNQIMTDTAGYSDMIFGLFGLLGFQFSPRIANDKGTKLWRIDAN
                     AHYGELDTLSQNSINMELIYTHWEDILRVAGSLKSGKVNATELTKSLQRNGQPTPLGK
                     AITEYGKVYKTKHQLRYISDEIYARQILEQLNKGEARHALCRNIFYGRKGKLYQTYYD
                     GMEEQLNALGLVTNAIIYWNSLYLEKVFEQMKAEGFDCSEEMIRRQSPLISDHINFVG
                     KYTFRYEAELSNGKLRPLNVEEF"
     gene            9763..10197
                     /locus_tag="ACF3MF_002196"
                     /pseudo
     CDS             9763..10197
                     /locus_tag="ACF3MF_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
     gene            10178..10912
                     /locus_tag="ACF3MF_002197"
     CDS             10178..10912
                     /locus_tag="ACF3MF_002197"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFE3928145.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            10945..11808
                     /gene="ant(6)"
                     /locus_tag="ACF3MF_002198"
     CDS             10945..11808
                     /gene="ant(6)"
                     /locus_tag="ACF3MF_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003109014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HFE3928146.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYPKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHLNQILRFELLRMMSWKVGIKTEFSLSVGKNYKYINKYID
                     EDLWNRLLSTYRMDSYENIWKSLFICHQLFREVSKEVAELLGFDYPEYGKNITRYTED
                     MYKKYVENDYF"
     gene            11852..12379
                     /locus_tag="ACF3MF_002199"
     CDS             11852..12379
                     /locus_tag="ACF3MF_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="HFE3928147.1"
                     /translation="MESTDVINEIRGILPRNSIGKYDLLTIFTHKTVFDKIVKVLSLD
                     FQNKVDYVAAPEAIGWILGTAIAKELGVGFIGVRKGDKLPYAKEEIISTHFTDYSGQD
                     KSFEISKSSIVRNKRVLIVDDWIETGSQMKALIALLEKLDCSIIGLATIGIDINEVTQ
                     KWIDSSFVAYIGLNI"
     gene            12607..13926
                     /locus_tag="ACF3MF_002200"
     CDS             12607..13926
                     /locus_tag="ACF3MF_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSsu5 family transposase"
                     /protein_id="HFE3928148.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGRLSSDSGLVLVKELMNTFGFSH
                     LAKQWLHITDHRAYFTHDNLAILEQLIMQLIAGYSADSSANLLRRDPVFQAVLGKKQL
                     ASQSSISRFLDRFTEENIDQLQALNQSLIDKARLIRNDTELIIDVDSTHSDTFGRQEQ
                     TDYNAHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKAFINPLLHHYKSTLPH
                     TEILVRGDSGFATPEVYESCEATESQYVIRLKSNRRLSQLAEHSVLYGDNQEWEEREV
                     QYFSLPYQAQSWSKPRRVCIRSVREGGELLFHHAFIVTNLSDNVSPEVIFSLYGKRGT
                     MENFIKEAKGGFYFDKTDSPRFLENHVRMMISVLAYNLVNFLKSIGFDKVNQGMTIHS
                     IRLILLKVAGKLVQTGRQVYLKLSSYHVYQTEFYKVFERLRRSKQWI"
     gene            14117..>14376
                     /locus_tag="ACF3MF_002201"
     CDS             14117..>14376
                     /locus_tag="ACF3MF_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010726733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="HFE3928149.1"
                     /translation="MNYSGFFEVEASIKVNQGSFKGVLSPTQRFKSQEELLSFVSSKQ
                     AKIGNQEGIIADVQTKEKKTNSPSLFSLSSLQSKVNQLYKATA"
BASE COUNT         4903 a         2197 c         2803 g         4473 t
ORIGIN      
        1 cacgatcata taagatttct tgaacttcac gatagctaag gttataacga agatagtagc
       61 ccacggctac aataatcaca tcctgctgaa attgctttcc tttaaaatga ttcatcgtta
      121 ttcctcctgc tatctttttc tattattcta tcttatttga tagtagattt aaaactttgc
      181 aacagaacca attatcttat cgtagatata tattataaat ttaataagaa agcgaggtga
      241 gaatcgtgaa aaaaacgata ctaagtattt tttcagtatt tacaatatta attgggggct
      301 attttctttt gaatttagat tctgttaatt caaacgctca aataaaagat caaagagtag
      361 ctgaacataa taataaaaaa atgagtttga ccaaaaatat ctattctatg tcagatgaag
      421 aattgtataa agaatttggt gatttatccg gggaacagtt agaagaaagt attccaggaa
      481 ttagtgactc agataaaatt gttgtcttgt ctgctggtgg gcaattaatg ggagatggca
      541 aatccgaatt agttagttat aaacaaaatc acagacagtt tattgatgtt aatactgatt
      601 ccaacgctat ttcgattaag gatctaaaag agcttttaaa tagtaaaaga aatgaattaa
      661 agcagataaa agaaactaat tcagtggaat tagagtaaag gaagattcat tatgaaaaag
      721 atttttggtg tttctgttgg gctacttatg atgttaacat ttggaaatgc agtatatgct
      781 gctgagaaag aagttatttc agatccagag cagtacgcct cacgatactt tgctgatttt
      841 gaagaagaag ataaagtact tgcattgcca gaaggtggtt ttttaaaagg ggaagctaaa
      901 attgtatcta tggataatcc agatataatt caaggttcat ataattcaga aactgatcct
      961 gcttcagttt cagtgacaga agcaaaaaaa attgttgctg aaaaattcaa aaatgatatt
     1021 gaaactactc caattatgcc tcgaggagca tttccacccg atgttggtac tagcggacac
     1081 cttcttgtac tagcaggagg aggaagctat aaatcacagc catttagtgg tgcgggatgg
     1141 cgttttggag gtatgggtgt aaaaccagct gatggtacag gcaacttttt acgttggaaa
     1201 tcctacattg acgatggaag agtaggaaat gtaaatcaag ccaacgcaac taaatctggt
     1261 tctattcaag gaatggcatt gtatgctcgt gaaggattca aatactttgc accaaacggg
     1321 cctggttgga caatgaatat aggtatttat tacacttata atcctgttgc aggtacgtat
     1381 tatgttgttc aaaatattta ataaaacagc acaaagagat ttctttgtgc tgttttatta
     1441 tttttagttg ttgacaaaca ctaaaatata aaatataatc aacacataaa cgaacgtatg
     1501 ttcggcaaga aagcagggga tttttatgga tgagatggtt ttaagtactc agaaatggct
     1561 aaacaagaaa tacagtaatg ttacagggtt tgataaggtt ccagaaaatg ggcgaacagg
     1621 gtggcctaca atctatggac ttattgaagg actacaagta gaacttggta ttactaatct
     1681 agtagctaat tttggaccta ccactgaaaa aatgtacgat aatcaggtta ctcctaaatg
     1741 gggcaaaaat ctacctaaaa atattgtatt tcttattcaa ggtgcctttt ggtgtaaggg
     1801 gattaatcca ggtggcttcg atggggtata tactccatat ttagatactg ctgtaaaaga
     1861 gttgcagact gatgcagggt ttaatggaag cgctgtaact ggagttttgg atgcgaaatg
     1921 ggccaaagcg ttatttgata tgagtgcttt tgttcttgtt cccggcggag atagtaaaat
     1981 tagaaaaatg cagcaatggt taaatgtaaa ttatttagaa tacacgggaa taatgccttg
     2041 tgatggtatt tatcaaagaa attcaaatca agcattaatt tttgcattac aagctgaact
     2101 aggatattct cccagtgaag caacagggtc ttatggtaat gggacaacta gtaaaactta
     2161 tcctgtgtct gaaggtaact cgggaaacta tgtaagaata attcaatatg gattatatgt
     2221 taatggttat tttgaagacg gtacattcga tggtattttc actaaatata tgggtttaga
     2281 agtactggca ttccgaaaat ttatggtatt gcctgaatat actgaaatag cagatgttgt
     2341 tgtaataaaa ggactattgt ctagcgctgg agatattaga agatctgcag atggcgcaga
     2401 tacttctacg caattaacta gatctcaaat ccaaacattg gttgataatg atataaaaat
     2461 agttggtaga tatcttactg gtactgttgg aattggaaaa gatgaacgaa ataagtatct
     2521 aactacagag gaattgaata atattttttc taaaaattta tctgtgtttc ctatctatca
     2581 agatggaggt gcagcattag cttattttac ttatgatcgt ggcttatcag atggtaagaa
     2641 ggctatagat gcagcaaaaa atctaaatat accattaaca acagttattt attttgctgt
     2701 tgatctagac atgttagggg aagaaattct tgcatatgct ggagaatatt ttaagggggt
     2761 atctgctgta atgtcatata gcgggtatca aacgggtgtt tacggaacaa gaaatgtttg
     2821 ttctcaaata atcaataacg ggtatgcttc gtttgcattt gtttcagata tgtcgactgg
     2881 ttatagtggg aatttaggtt ttcctatgcc tagacaatgg tcttttgatc aatttgttga
     2941 atttaccata ggaagtggca acggagctgt tggtatcgat ttaatcgcta catcgggtag
     3001 agatagcgga tttaatgagt tatcaaatga tactaataat gataattaca ttgccaaata
     3061 caatcagaag gttataaatc agatggtacg tgcgtatcaa tatctatcac aagctggtct
     3121 tgataatcct tggaaccctc atttgacatt ttatagatat gtaaattatt ctggtttgtc
     3181 atgggacatc atttcttctc ctgtaacaga gcatgataga aaaatttatg atgaatatag
     3241 gaataaatta actaatagcg agggcctgta taattatttt atagatccta atactggttc
     3301 aataataggt ttgcctcact taattgtgac gttacaatca cagatgtttc tagccgacac
     3361 aatcaatgat agtgtttctg actttgcagg ttggttagga gatttaatga cttgctgggg
     3421 tgaagttaag aaattaggaa tacaaatgga gcaaggtgta tttgcattag taggtacggc
     3481 tgcaggtgga acatttagtc tagaagattt ataccaagat gttgacgcgg taaatgttta
     3541 taccttagca aaaagaaatt ctgattcaac agctttatcg gctttaaaaa cgtactattg
     3601 tgataagggt gctattgata gatttaatca atttgttaag aacagatttg gttcttcaga
     3661 taaaatcgct tcagtaacaa atagtttatt agaaaatgac gaaacagttg atatcttagg
     3721 tgtagggata atttcatttt tcattgataa aatagttaat aattcacttg ggacagattt
     3781 tacttatctt gattttattg gagatgaggg gaaagttgca aatggatttt ctgaaaaaat
     3841 tattcaattt caagaaaata gaagtaaact taattaagaa tcgtttacta tttaaacagt
     3901 gtccttttcc tttttaaata tatacgataa aataagtata tgaattgtaa aaggacatga
     3961 tgattatgga agaaatagaa tggaataatc tgactcaaaa taataaaaat aattctggat
     4021 gtggaattat ctttatgttt gttatagttt tgggaatagt agtactttta ataactgtca
     4081 agatagtaga ttactttgcg aatactcctg aagaacaaat acagagaaaa cttcctgagt
     4141 ttgaaagagt accaccttat gatccaagag ataattcatt tcaagtaaaa aaattaaaag
     4201 agtctccaaa tgaaatgtgg tttgaagtta cagttgaatc aagcgacttc aaagaaaaaa
     4261 agaaagaata caattatatt gtaaaggcaa aagtatcaaa aagatttatt tttaacccta
     4321 aattagaaat atatagtgtt gtaatagaat aatagtgtta aaaaaattgt aaaagttaaa
     4381 gaagtcaaat tctgatgtga aaaataaaat ataccatgga agacataaaa gaaaaactgg
     4441 ataactagtt tatttaatgg cagaccgtta aggcctgcca tttttatgta ttttagcgga
     4501 ataaatataa tcatgcggga gtgtaaactt actgtttcaa aaagtatact ttttgacatg
     4561 ccttgatttt ctttgtttat gtatggcata ataaccacat aatacaattt gaaacgtttc
     4621 tgatttaatc tgattgtttt gaaacaattt tagtgaaaaa agggtagata aaaacgatga
     4681 gaaaattttt ttatatccgg gtcagtagtt atgatcaatc gatcgaacga caactgattt
     4741 ccgcgaagga attaggaatc cctgaagaat atatatttgt agaaaaagcc agcggcaaag
     4801 attttaaacg ccctgaatat caattaatga aacggatgtt tcgaaaagga gatttactct
     4861 atctacaatc attagataga ctaggcagaa ataaacaaat gattttagaa gaatggcgag
     4921 aattaactaa ggaaaagcag attgatattt ctgtgttaga catgcctctg ttagatactg
     4981 ctagttacaa gcaactagat gggttagaga cgcttatctc tgacttaatt ctgcaattac
     5041 tcagctatat ggccgaagac gagcggaaac gaattaatag ccggcaaaga gaaggcgtag
     5101 aagctgcgaa acaaaagggt gtaaaattcg gcagaaagaa aattgcttta cctcctgaat
     5161 ttcctgcgat ctattctgac tggaaagcag gaaagataac tgcagtctat gctatggatc
     5221 aattgggcat gaaacgaaat accttttatc gacgggtgaa agaatatgaa cataccttgc
     5281 accacttttc ttgatagata taacagctat tagacgggaa gggagagttt gaaaatggac
     5341 ttaacgaatc aaagggtcgt ttttactgga acgctgcagc aaatgacacg aacccaagcc
     5401 atcggtttgg ttcactcttt aaacggccat tgtcaatcaa gtgttacttc aaaaacaaat
     5461 ttcctggttt gtggtcagta ttctaagtcg ttgtttgatg attctctcta tacaaaaaag
     5521 gaacaaaccg cgcgggactt gattgcgtta ggtcatgaga ttaccatttt atcagaagtc
     5581 gaattttatg cgttaattag tcaacagttg aaagaatggc aacggtattt ataatcgtta
     5641 gtaaaattta caaggaggaa aatttttatg aagcgaaaat cttatgatcg ttggggcatt
     5701 gaaataacta gttttaatcg aaatattgct tttcacgtgg agtgtgactg tggggaatta
     5761 gcaaaaagtg tttatcaaaa aaattacttt tactgtccta aatgccatcg ccgatacggg
     5821 gtacatggaa catagaaacg aaatagtgcg gtagaaaagc gaatgaatgt agtatatttc
     5881 tacaaatcat tcgctttctt tattttataa atagttggtc gagagatccc gttttctttt
     5941 gcaatctctg caactggaat gccttgcttt aacatgtcca ccacggtttt aaaaactaag
     6001 cgtttttgcg gatctgttga gttaatagaa tactcgattg gtcgtccctt atatcggccg
     6061 gctttttgag ccaataatac tccttgccgc tgacgttcac gaattttctc acgctcgttt
     6121 tgtgcaatat aacttagcag tgataaaaac atatcgaaca tagcggtatc caggagttca
     6181 tttccagtat taaaatctaa aaactgtgca tctaatattt ttaacgctac ttttttctgt
     6241 ttcataaaag caactgtatt ttttatatct tcataatctc ttcctaaacg atctagtgat
     6301 gtaacgatga cgcaatcacc ttcacggata taatttagta atttttgaaa ctcaggacgc
     6361 tcagtatctt taccactggc tttttcttgg aataatttat caatgttaag tccttccatc
     6421 attgccaatt gtcgatccaa attttgatct tgtgaagata ctcgaatata gccaattttt
     6481 cccataaaaa actccttttt aaaagtgata taatttacat gtaaaattta cttgtagttt
     6541 tactgctatc atagcatttt taaaaataaa ttttatgtag acttaaaatt tacttcatgg
     6601 agggtttaaa tggatgaaat caaaagtaac aaaaaagcat ttggcattta tttaggagaa
     6661 cctagtacag aacaattaaa ccaatttttt tatttgcatg aaaaagattt agaattgatg
     6721 gagactatac gacgaccagc tactagatta ggttttgcac tacagttagt ctcactacgt
     6781 tttttaggaa cttttatatt agatcttacc aatattcccc aaaatgtatt gagttatgta
     6841 gcaactcaac taaatattga tcctggagaa attatctact atagcaggag acagaccagg
     6901 tatcagcaca caaaattgat aaaatcacat tatggatatc aagatttcaa ccaaccggaa
     6961 atagaaacat acctagctaa ctggctttta aatagagcgc tgtatacaac agaatcttca
     7021 gatatgttgt ttgatatgct tctaaaaaaa tgtctggatg aaaagattgt tttacctgga
     7081 attactactt tttctcgttt tgttgctagt gcaattgaaa aagctgaaga gcatttatac
     7141 cgacaattgt ctttggttcc aactgaagat gagagaaagc ggcttctcaa tcatttagaa
     7201 ttaattggaa ctccagttta tggggcaata atcaaaatgg acattttgag aaccccgtta
     7261 gctgacgata gtcataaaga aatagccaga ggttttgacc gactaaagca atttcaagct
     7321 ttctctactg aaaaatggaa gatggaatct attcctgaag ggaaaataaa agttcttgca
     7381 aattatgcat ttaaagctaa agctcaatta attcaacgaa tgagtgaaca gaaaaaactg
     7441 gcgttgttag tggcatttat tttcatatac aaacgtaagg ctatggatga acaaatttta
     7501 gcactatcta atttttttga aactgttttt agacgcgcca aaaataagga atctaaagaa
     7561 cgtcttcgta ccataaaaga tctagatcga gccgcatcga cactttcaga tattgtagat
     7621 ttagtaatgt ccagtcattc tgatactaat gaactatccc ttcgcgatcg tatcttagaa
     7681 aaatattctg aggaaaatgt taccgaagct gtatcgcaag ttcggctatt ggttaaaaat
     7741 gatcgtgaac caatagccat ttctgaactt ctgaacactt atcgaaagtt cagaaaattt
     7801 attccggata ttttaactac actaacattt gacagcaatg actacggtaa caactgtaag
     7861 gaactctgga ccttcattaa taatagattt cctaagccga ttacttacaa aatgtttgga
     7921 gctattaaac atactcttcc aaagaaatgg atttattaca ttcatgaata ccctgaacaa
     7981 actaataaat gtgtattgat tgcagctgtc gaattgttaa ttcaatcttt aaaacgccat
     8041 gatatttata ttcctcagag tgtcttatat aacaatccta tggattgctt gattgatgag
     8101 aaaacttggg ttcaacaaaa atacgtttta ttagaacaac tagatcttcc ttcttcagca
     8161 aatgaaatgt ctttatggtt aaagaacgat ttggaactgt cttataaaga agcgctaaat
     8221 cgttggccta cttctaaaat ggccagaata gaaaatgcag atcgcctggt tgtctctaga
     8281 cttaaaaaga catatgaaaa aaaggaagat aagtctttta gacgtcgcat tcagcagtta
     8341 cttcctaaaa ttgatttgtc agatttgtta ttggaagtaa accaacagtt aaatcttact
     8401 caatcattta accacttaag tgacaaggac accaaaatga aagacttgga tattagttta
     8461 ttagcagttc ttttatcaga gtcctgcaat attggttttt ccccggtttc aaaagaagga
     8521 tttgattctt taaagtatga tcgtcttgtc tatgtcaatc atcattatat tcgagtggat
     8581 acactttcag gagctaatca aaaaataata catgcacaca ggaaacttgc cacctctaag
     8641 atatggggtg atgggcatat ggcttcagct gacggtattc gttatatcac accacaacgt
     8701 tccctatatt ctagaagtaa tccaaaatat tttggccgtg gtcgtgggat cacattctac
     8761 aattttgtct ctgatcaata tatagggttc cacggaatgg tcgtttcagg gacactgcga
     8821 gattcgcttt accttctaga aggattcctc aatcaaccca gcgaattaac tcctaatcag
     8881 atcatgactg atacagctgg ttatagcgat atgatttttg gtctctttgg cttattaggg
     8941 tttcaattta gtccaagaat tgccaatgat aaaggaacca aactttggcg aatcgacgct
     9001 aacgctcact acggggaact tgatacgttg tctcaaaatt caattaatat ggaactgatt
     9061 tatacccatt gggaggacat tcttagggtt gcaggttcgt tgaaatctgg aaaagtgaat
     9121 gcaacagaat taacgaaatc tcttcaacgg aatgggcaac ccacgccttt aggaaaagca
     9181 ataactgagt atggaaaagt ttataagacg aaacatcagc ttcgttatat ttctgacgaa
     9241 atatatgcac ggcaaatttt agaacaattg aataaggggg aagctcggca tgccttatgc
     9301 cgtaatattt tttatggacg aaaaggaaaa ctctaccaga cttattatga tgggatggaa
     9361 gagcagctca atgcattagg attagttact aatgccatca tatattggaa ctcactgtat
     9421 ttagaaaaag tatttgaaca aatgaaagct gaaggattcg actgttccga agaaatgata
     9481 cgcaggcaat ctccactaat tagtgatcac atcaattttg ttggtaagta tacgtttaga
     9541 tacgaagctg aattatccaa cggtaagtta cgtccattga atgtagaaga attctagcaa
     9601 tgttcgggtt ttgcatgcta ccgcactatt tcgtatgact gttccagcga atcacttcga
     9661 atagaaaaag agaaaaacac gagaacagcg ttaaatcaac gtttcttgtg tttttacttt
     9721 tgtgctaccg cactatttcg tttctatgtt ccatgtaccc ctaagaacga aagcttatgc
     9781 gaattaaaaa agcaggcaga aatttaccct actgctctaa agaaaagctt gatgaacttt
     9841 tttatatttg aagctgaatt ctctttaatg tttgtaaaag caaatgcggg ggtagaggat
     9901 aaatattata ttgcaggcca tgtttttcgt attatttcat gcttaaatca agtactattt
     9961 gcatgtaata atgcttattg cattaacgaa aagaaagcta taaaactgct tgaaactttt
    10021 gaatataaac ctgaaaaata tgccgaaaga gttaatcata tttttgaagt actcggtctt
    10081 tctctttttg aatgctacga tatgaccgag aaactttata aagaagtgaa tgaaattgta
    10141 tcggagataa ataacttttt aaacgaggag agttcagatg aaagaaaaca aatatgatga
    10201 taatatattt tttcaaaaat acagtcaaat gagtcgctcg cagaaaggac tggctggtgc
    10261 gggagaatgg gagactttga aaaagatgct acctgatttt aagggtaagc gtgtgcttga
    10321 tttaggatgc ggctatggat ggcactgtat atatgcgatg gaaaacggtg cttcctctgt
    10381 agtaggtgtt gatatttctc ataaaatgct cgaagtagca aaaggaaaaa cccattttcc
    10441 acagattgaa tatgaatgct gtgccataga agatgtggat ttcccagagg agagctttga
    10501 tgtaatacta agttcgcttg cgtttcatta tgtagcagac tatgagaatt taataaaaaa
    10561 gatatatagg atgctgaagg ctggtggcaa tttagttttt acagttgaac atcctgtttt
    10621 tactgctcat ggaacacaag actggtatta taacgaaaaa ggagaaatac tgcatttccc
    10681 ggtggacaat tattattatg agggcaaacg gacagctatg tttttggaag aaaaggttac
    10741 aaaatatcat agaacactga ccacatatct aaatacactg ctttcaaata gttttataat
    10801 aaatcagatt gtggagccac agccgccaga gaacatgatg gatattccgg ggatggcgga
    10861 tgaaatgcga cgcccaatga tgctgattgt atcggcaaaa aagaagatgt aataatatag
    10921 aaaaaataaa cgaggagtat gtaaatgaga tcagaaaaag aaatgatgga tttagtactt
    10981 tctttagcag aacaggatga acgtattcga attgtgaccc ttgaggggtc acgcgcaaat
    11041 attaatatac ctaaagatga atttcaggat tatgatatta catattttgt aagtgatata
    11101 gaaccgttta tatctaatga tgactggctt aatcaatttg ggaatataat aatgatgcaa
    11161 aagccggagg atatggaatt attcccacct gaagaaaagg gattttccta tcttatgcta
    11221 tttgatgatt acaataaaat tgatcttacc ttattgccct tggaagagtt agataattac
    11281 ccaaagggcg ataaattaat aaaggttcta attgataaag attgtagaat taaaagggac
    11341 atagttccga ctgatataga ttatcatgta agaaagccaa gcgcaaggga gtatgatgat
    11401 tgctgcaatg aattttggaa tgtaacacct tatgttatta aaggattgtg ccgcaaagag
    11461 atactgtttg caatcgatca tctgaaccag attctacggt ttgaactact taggatgatg
    11521 tcgtggaagg ttgggataaa gacagaattt tcattaagtg ttgggaaaaa ttataagtat
    11581 attaacaaat acattgatga agatctatgg aatagattat tatctacata tcgcatggat
    11641 tcctatgaaa atatttggaa gtcattattt atatgccacc aattgttcag ggaagtgtcc
    11701 aaagaggtag cagaactact ggggtttgat tatccagagt atggtaagaa cataacaaga
    11761 tataccgagg acatgtataa aaaatatgtt gaaaatgact atttttaaag attagcaaag
    11821 attattaacc ataagcaagg ggtgtaaatg tatggaaagt actgatgtta taaatgaaat
    11881 tagaggtata ttacctcgta actcaattgg aaaatatgat ttactaacta tttttacaca
    11941 taaaaccgtt tttgataaaa ttgtaaaagt actatcattg gattttcaaa ataaagtaga
    12001 ttatgtggct gccccagaag caattggatg gatactaggc actgccatag ccaaagaact
    12061 tggagtgggg tttattggag taagaaaagg tgataagctg ccatacgcaa aagaagagat
    12121 tatttcgaca cattttaccg actattcagg tcaagataaa agctttgaaa tatctaagag
    12181 ttctattgtg aggaacaaaa gagttttgat tgtagatgat tggatagaga caggttctca
    12241 aatgaaggct ttaatagctt tgttagagaa attggattgc agcattattg ggttggctac
    12301 tattgggatt gatataaatg aggttactca aaaatggata gacagcagtt ttgtagctta
    12361 tattggctta aacatataat aaaccgaaag aaaatcttga atcaaaattt tggatggcgt
    12421 taatttacaa tacaacgaaa gatgtttacc ctgaataatt catacttttt aattgaaacc
    12481 gtctgaaact gcctaacggc agtctgataa ttactttttt agtttcaccc cttaagtgat
    12541 gaaaaaagaa ccccattctg ctatggtaaa ggtgacgaaa ccaaccataa gaaaggagtt
    12601 cttctcatga ctagcttaca caaaaatcaa gttaaattca attcaaatat cactatttca
    12661 cataccggtg gtcgtctatc aagtgattcg gggttagtcc tggttaaaga attaatgaat
    12721 accttcggct tttcgcactt agctaaacaa tggctccata ttacagatca tcgggcttat
    12781 tttacccatg ataacttagc gatattggaa cagcttatta tgcaattaat tgctggttac
    12841 tcggcagact catcagctaa tctattaaga cgggatcctg tctttcaagc tgtactcggt
    12901 aaaaaacagt tggcatcaca atcctcaatc tcacggtttc tggatcgttt caccgaggag
    12961 aacatcgatc aactccaagc attaaatcag tcattgattg ataaagcacg tttaattcgc
    13021 aatgacaccg agttaatcat tgatgtcgat tccacacatt cggatacctt tggacgccaa
    13081 gaacaaacag attataatgc ccattatcaa acctacggct atcacccatt agttgccttt
    13141 gatggactga ccggagattt cttaaaagct gaactgcgtt caggcaatca gtacacatct
    13201 aaaggggtaa aagcctttat caacccgctt ttacaccact acaagagcac gttacctcat
    13261 accgagatat tggttcgggg tgacagcggc ttcgccacac cagaggtgta tgagtcttgt
    13321 gaagcaactg aaagccagta cgttatccga ttaaagagca atcggaggtt aagtcagtta
    13381 gctgaacatt ctgttcttta cggggacaat caagaatggg aagagcgaga agtgcagtat
    13441 ttttcactac cttatcaagc acaatcctgg tcgaaacctc gtcgtgtctg tatacgctcc
    13501 gtccgtgaag gaggagaatt gctatttcat catgcgttta ttgtgactaa tctatccgac
    13561 aatgtctcgc ctgaagtcat attttctctt tacggcaagc gaggaacaat ggaaaatttc
    13621 atcaaagaag cgaaaggtgg cttttacttc gataaaacag atagcccgcg tttcttagaa
    13681 aatcatgtca gaatgatgat cagtgtcctt gcatacaacc tcgttaattt tttaaaaagc
    13741 attggttttg ataaagtgaa ccagggcatg acgattcatt ccatccggct gatattgctt
    13801 aaagtagccg gtaaacttgt tcagactggg agacaggtct atctcaaact gtcaagttat
    13861 catgtgtatc aaactgaatt ttataaggtt tttgaacgcc tgcggcgatc caaacaatgg
    13921 atttagacta gttatcacac aaatttttta accgattctt tttcaaggga ttcgtctgcc
    13981 cttaaataga caaataattt ttattatgat cttcttccgt aggcatcctg ttcgaaaaca
    14041 cattattttg gaagaaagta tctgcctaat ttaaaaattg gcaatttgtt caaaaaaaca
    14101 ggttaaattt agagctatga attattcagg ttttttcgag gtggaagcta gtataaaagt
    14161 aaaccaaggg tcgtttaagg gcgttctaag ccccacacag cgttttaaga gccaagagga
    14221 acttttatcc tttgtttctt ctaaacaagc taaaataggc aatcaagagg ggataattgc
    14281 tgatgttcaa accaaagaga agaaaacgaa tagtccgagt ttgttttctt taagtagttt
    14341 acaatcaaaa gtcaatcagc tttataaagc gacagc
//
LOCUS       DAXQKX010000062        14363 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.064, whole genome shotgun sequence.
ACCESSION   DAXQKX010000062 DAXQKX010000000
VERSION     DAXQKX010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14363
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.064"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(257..598)
                     /locus_tag="ACF3MF_002202"
     CDS             complement(257..598)
                     /locus_tag="ACF3MF_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFE3928150.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(598..828)
                     /locus_tag="ACF3MF_002203"
     CDS             complement(598..828)
                     /locus_tag="ACF3MF_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFE3928151.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            1124..1462
                     /locus_tag="ACF3MF_002204"
     CDS             1124..1462
                     /locus_tag="ACF3MF_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928152.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPIQIET
                     LVQRISTREDFAIVECEIVAIFVEEGILHDPTHINVDKWQPLIYKLREYTTANQSLSL
                     NFRFQEFKES"
     gene            complement(1667..2242)
                     /locus_tag="ACF3MF_002205"
     CDS             complement(1667..2242)
                     /locus_tag="ACF3MF_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006974 - DNA damage response [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HFE3928153.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPEQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGF
                     YEWNEEKDKFMFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRMPLVL
                     TEEQIEPWVTDVSFARKIITQQMPELVMEKV"
     gene            complement(2607..3188)
                     /locus_tag="ACF3MF_002206"
     CDS             complement(2607..3188)
                     /locus_tag="ACF3MF_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFE3928154.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASETGKGQFYYYFS
                     SKKEVCLAVIHAHMVVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWIKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(3371..3997)
                     /locus_tag="ACF3MF_002207"
     CDS             complement(3371..3997)
                     /locus_tag="ACF3MF_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HFE3928155.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFSLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(4019..5347)
                     /locus_tag="ACF3MF_002208"
     CDS             complement(4019..5347)
                     /locus_tag="ACF3MF_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HFE3928156.1"
                     /translation="MEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTCI
                     NIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARFL
                     SNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPEK
                     LVIIGAGYIGLEFASMFNEYGSKVVVLDAHPEFLPREDEDIAQMILEDMTNAGIEFHL
                     GVSVDQVADQESTAAVTFTENGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDRG
                     AIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVPY
                     SVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETDL
                     ILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(5506..5907)
                     /locus_tag="ACF3MF_002209"
     CDS             complement(5506..5907)
                     /locus_tag="ACF3MF_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HFE3928157.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(5993..6199)
                     /locus_tag="ACF3MF_002210"
     CDS             complement(5993..6199)
                     /locus_tag="ACF3MF_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928158.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(6294..7796)
                     /locus_tag="ACF3MF_002211"
     CDS             complement(6294..7796)
                     /locus_tag="ACF3MF_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HFE3928159.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(7814..8269)
                     /gene="argR"
                     /locus_tag="ACF3MF_002212"
     CDS             complement(7814..8269)
                     /gene="argR"
                     /locus_tag="ACF3MF_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFE3928160.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(8367..8984)
                     /locus_tag="ACF3MF_002213"
     CDS             complement(8367..8984)
                     /locus_tag="ACF3MF_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFE3928161.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            9205..10578
                     /locus_tag="ACF3MF_002214"
     CDS             9205..10578
                     /locus_tag="ACF3MF_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFE3928162.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLILSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            10653..11765
                     /locus_tag="ACF3MF_002215"
     CDS             10653..11765
                     /locus_tag="ACF3MF_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFE3928163.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(11837..13474)
                     /locus_tag="ACF3MF_002216"
     CDS             complement(11837..13474)
                     /locus_tag="ACF3MF_002216"
                     /EC_number="4.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004612 - phosphoenolpyruvate
                     carboxykinase (ATP) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HFE3928164.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(13642..14250)
                     /locus_tag="ACF3MF_002217"
     CDS             complement(13642..14250)
                     /locus_tag="ACF3MF_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFE3928165.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
BASE COUNT         3922 a         2976 c         2536 g         4929 t
ORIGIN      
        1 tttctgttaa agtattgtcg cgacttttcg tatacgttaa gatatgtcgt gaaaaaacaa
       61 gttttgtgac acaaaaaaac gaatgacttg aggaaatcac ctcaatcatt cgtttaaaat
      121 gctatatatt ctttagttta agatacggaa attaatccca tcgaccacac tagtagaatg
      181 aacgacattt acttggcctt tttttaattt cgttatgttt agcatataaa aatattatag
      241 agtttactta caatgcttaa aacatatact gtataatctg atcaatttta gccatgtctt
      301 gcaatggtaa gttttctatt tttttgagtt ttcgttcctt aaaatcaaga gattttaatt
      361 gtgtaataat tacttgtcct tttatatcta gctcttcagg taatgagtaa cgtgtcggta
      421 aattctttat agtggaagta attggacata tgaccgaaaa cattgtttta cggttaaatt
      481 cataacgaga gacgactagt cctggtcgtc ttttttgaat ttcttttcct actgagggat
      541 caaaatcaat ccatacaata tcaccttttt taggaatata aattctttct tctgacacta
      601 taaaatttct ctcccttcag gagttaaatc ttcccattcg tctttctcat aatactcggc
      661 ctcttcccca ccactaaatg gatcttcaat ttttggaact aacgtaattg ttccatcatc
      721 agaatacaca acgatatatt cttggttttc tgaaggtttc tttccgttat cagaaggtaa
      781 agttaccact acagaacttc cttgtaatct agattttgta acaagcatta tcatcactcc
      841 cttaataaaa gtatactata taacactaag taacgcaaaa ttcccctttg taaactatct
      901 agaaaattgt tttgtttaaa gtatatctta ttggatataa atagaaataa attgtagcca
      961 gttcattttt tctttaaata aaaaaataat ccaagaaaca ttgaacctat ggatccaaaa
     1021 gctacccaaa tactatagct aactccccgc taccttcaat cttgcagata aaacgctttg
     1081 gaaaaaaatc gagaaaatcg caaagacgac aggccatcct atcatgcctg attataaaca
     1141 aaaagctggc tattcctttt gctctgacaa atttcaattg ggaaagttca cgaaactagc
     1201 aggtgaagaa gtttcaactg ttcggattaa agaatgcccg attcaaatag aaacgttggt
     1261 tcaacgaatt tcaactagag aagactttgc tattgtagaa tgtgagatcg tagctatttt
     1321 tgtagaagaa gggattttac atgatccaac tcatatcaat gtggataaat ggcaacctct
     1381 tatctataaa ctcagagaat atacaactgc caaccagtcg ttaagtttga attttagatt
     1441 ccaagaattc aaagagtcat aatgataaac atcattaggt ataaataaaa aagactcgca
     1501 gaacgagtaa aaaacaaata gaagctatac cttagaaagg tcgactgtga ctctatagat
     1561 gcagtatatg cagcttatga gcatttcttc tgttctcttt gtttttggga tctgtgctga
     1621 agtctttttc gttttttgcc gctctttctt tgaaaaatcg attatgttat accttctcca
     1681 ttactaattc aggcatctgt tgagtaatga tttttcgcgc aaaagaaaca tctgttaccc
     1741 aaggttcgat ttgttcttca gtcaagacaa gcggcattcg gtcatggatt ggtgcgactg
     1801 tgcggttagg ttcagtagtc attatgattg attctgccat tttttcatcc tgatggctac
     1861 gataaaaacc gccaatatac actatttttt ccttatttga aaacataaat ttgtcttttt
     1921 cttcattcca ctcataaaag ccactcattg ggaaaacaca acgattttgc aaaaatggtt
     1981 gatgaaaggt ctttttttct tctactgtct ctgcacgggc attaatcatc aattgtcctt
     2041 ttttaaatcc ggtaaatccc cacttcatga tttccggagt gaggatgttt tcttcctctt
     2101 ttcttaacgt cacaacaaga tttgacggaa aaacttctcc agctgctaat tctgctgcct
     2161 gctccggttg tttcgtctgg gcttctcgat aataattctg aaggagctct gactctagat
     2221 caaaaaaata acgaccacac atcctaatcc ctcccaatct ttttttctat catacactgc
     2281 aacaagaagt ccgtaccaac aaaacgcttt caatttgtgt agaactaaaa aagttgtgac
     2341 aagtgacaaa ctctccagtg aatggtattc tcctgccaac tcctcggtca caagtcacaa
     2401 tattcaacaa acatgagaag ctgctttttg aaattgttcc ttgtgactcg gagtgaaacg
     2461 gcaggcttac gacctctggg taaacggtgt tccagaagta gcttcttcga aaaataagcc
     2521 gaaatttcac aaaaatttga gaagcaattt tcgtaaattc cttcttattt cttgaagctg
     2581 accacttctg tcacaacctc taattattaa agaacctttt gcgaagttaa caatctttct
     2641 ttgatcaatt gaaaattttg tctaagtagt gatagatcct gtgtgacttt caacaataag
     2701 atacttccct ggatttcagc aatcaacgct ttggcttgac ggtctgcttc ttcatcggac
     2761 agtttttctt cagaaagtgc caggatattt tgtttcgtat acttgatcca ttgattgact
     2821 aattctagta gcaacagacg gtattcttca tccactgtac tcaactcaat aatcaaatta
     2881 cctacaggac agccatgata agtgatctgt gtctcatgat cagcaaaaat ccagtccaac
     2941 atttcttcta atgcttcttc tggctgtttt ccagcattta agatgtcttc gaacaattct
     3001 gtctgccaca cgaccatatg cgcatggatc accgctagac aaacttcttt ttttgaagaa
     3061 aagtaataat aaaattgccc tttccccgtc tcagaagctg ctagaatatc tcggattgac
     3121 gtttcatgat agcctttttt ataaataaga tctttggtcg cttccaagat cttttccttt
     3181 gttttcaatg atattctcct ttttcatttc tcatagtcct atattataca ataaattcat
     3241 cattttttct tcttaatcgt ttaaaaaaga ctgtgccaaa ttatctgaca cagccctcac
     3301 tataaaactg ttctcatata gctagatgtt cattgattca agaactgcga ggacaaaagc
     3361 aattcctatc ttatgatagt tgctctaata cttcctctgt tgtcatcact tgatctgcaa
     3421 taaagccaaa gttcgtcaac gctgcatcca ttgcttcttg accaggagca ccaattgcat
     3481 ctgtcgctac cacaacattg aatccactct ctaccaattc acgcatatgg gaatcgctac
     3541 acaagtttcc gttcattcca ccaagaatca ctgtgtcgat tccatttttt ctcaattgga
     3601 gcgccaaatc attgctttct ggtccaaaga ttttatgagg agagctgata atcgtatttt
     3661 catccaaata tggtttcaat tcttcgatga aatcagctcc tgaaccttct tcaactgatt
     3721 catattgact tttcctagca aacatctgtt gctcaagcat catatgttct cctgcaccgc
     3781 caaattgcca tttatggtca tgtgggtaaa aataatgagg agaaataaag agtttgtatc
     3841 ctttttcttt tgcttgtttc accatttcga tcatgttttc gatcgtattg tatttttcta
     3901 agatatcttt tgtcaaacta aagccaccgc ctgctggttt caagaactcg acttgcgggt
     3961 cagtgagaac tactgctgta tttttattat tgaacatggt ggattctcca ttcgttattt
     4021 attttaatac atcatttaaa gcttcactca ttgttggatg agaatagatt tgatctctca
     4081 ataacgtata aggaagtttt ccattcatag ctagcgaaat caagttgatg acttcatgag
     4141 aatcttccgc atagatactt gcccctagaa tcaagtcagt ttcagggtcg actaaaactt
     4201 tgaatacacc tttaggatct tctaatactt gtgctttagg gacaccgctt gtcatatact
     4261 tgaataattt gtaattgacg ccttgtgctt tggcttgttt ttctgttaaa cctacattgg
     4321 ataaagtcgg agtgataaat acactgtaag gcacagcttt ccggttattc gttgttcgtt
     4381 tattctcgcc cttcaactga tccataatga ttcgataatc atctagagag atataagtga
     4441 actgcaatcc gcctttgacg tctccaatcg cccaaatgtt gtctgcatct gtacgaaggt
     4501 attcatccac agcgattgct ccgcgatctg ttagtttaac atctgtattt tctaatccaa
     4561 gtgatgctgt acttggtttt cttccagttg cagccaaaac ttttgacgct tggattgtta
     4621 cttcttggcc attttctgta aaggtgacgg cagctgttga ttcttggtct gctacttgat
     4681 ctacagatac acctagatgg aattcgattc ccgcatttgt catgtcttct aaaatcattt
     4741 gcgcgatatc ttcatcttca cgaggaagaa attcaggatg ggcatcaaga acgacaactt
     4801 tagatccgta ttcattgaac attgatgcaa attccaagcc aatatatcca gccccgatga
     4861 tcactaattt ttccggtaat tgttcctgat ccatcgcttg cgtagaatca atcaagtagc
     4921 gacttgtatt caatcctttg attggtaaaa tgattggttc agaaccagta ttgatgaaaa
     4981 tccgttcgcc ttcaacaatc actttttcac cattattcgt cacttcgatt tgatggttag
     5041 aaagaaaacg tgctgtaccg tccatcactg tcccagttgc ctcatcgctg atcatatgat
     5101 aatttttggc gcgaagcatg cccgtcaatt tttctttccg agcaacagcc tctgtaaagt
     5161 cgattcctct ttctccattg aaaatcaatg atttagaagg aatacagccg atgttgatac
     5221 atgttccgcc atacatacgt gttgactttt caacgactaa aaccgattcg ccttttgaag
     5281 ctaacgcctt cgctaaagtc ttaccgccct ttccaaaacc gatcacaata ttttgatatt
     5341 tttccatcct ttttccctcg cttctttttt tacctaccga ttggtacaaa aatatgataa
     5401 ccgataattg tctattctcc aaatcatctg ctttatttgt caaaaaaaac cagacaaaaa
     5461 gcggtccttt cacgttttta gtctggttcg atttccttta ttcttctaaa caatcgttac
     5521 ttctacatcg atatttcctc tagttgcttt ggagtaaggg cagaattcat gcgcatcttc
     5581 tgcaattttt tgggcttctt cttcgctgat gccatcgata tgcacttcta atactacacc
     5641 gatctgatag ccgccatcat ctaaattata aagagagaca cgtgctttta ctgtggactc
     5701 tgctgtcatt cctgcttctt tgatcatatg ttgtaccgcc ccattgaaac aagaagcata
     5761 acctgctgca aataattgtt ctggatttgt tccttctgca tggattcctg gaggagtgat
     5821 tttcatatgc atcgagccat ttggtgcctc gacttctcca ttgcgcccgc catggttgat
     5881 cattgctgtt tcgtatgctt ttttcattgt actgctcctt tcgattgacc atttgctact
     5941 tggctataat tatagtgtat gacaagtaag gcgctttcta caaaaattct gcttattcga
     6001 ataccagaat gccgtcttct actatttttc caaaaaacaa aaaaatacta ctcgtgaaca
     6061 acagcgtcat atttgttcca aaataaatag caatcttttc tacataatct tttatatgat
     6121 tgattttaag atacatatat accagaaagt tgaccccata aaccaatact gttaaaaaaa
     6181 taaccatatt cgttaccatt ttttcctcct tttgctggtc tccctaccag cactcgattt
     6241 aaccatacca ctttttttgc cgtccaagca actagccttt caaaaagact ggtttattct
     6301 gctgttaatg attcaagatc agaaaaatgt ccgaataatt ttgctaattt tactaacgcc
     6361 aacttgttct ttccgaattc atcattttct atctgtaata ctagtaacgg ctcatgtaag
     6421 cttaaacgga tcaaaaacca gccgtttccg tatggctctt ctagatcata tcgaatacct
     6481 tcttcatttt ccgggtcgaa gttcatccct ttttcttctt ccaacagtcg cttcatttct
     6541 tctaatatct tgtttccttg ttcgcgtggt tcatcgctga acaattttaa tcggatttct
     6601 tgtacttcta cgggctgttt caactctttg atttgttcat ctaatgtgat accttttctt
     6661 tttaattctg gcaaaagcat caggatcttt gcgatgacat atgcaccatc atccagaaaa
     6721 tagttttcct tgaatgcagc gtgtccgctt gtttcgatgg ctagctgtgt atctttccca
     6781 agacggttaa gttctaatgc tttattgatt acatttcgat agccggaaat ataacgaact
     6841 tggatgcctc ctttttcttc aatgaatctt tgtagatgag aagaagtagg ggaattcgtc
     6901 acgattcttg ttcctggatg ctcttttaat acgattgtac ttaatactgc gatcaaatta
     6961 tttcgattga tcactgttcc agaagcactg acaactgcag aacgatccac atctgtatcg
     7021 aaaatgatcc caagatctgc ttcatttgct aaaacagcct gcttgatact ttccatcgct
     7081 tctttattat caggatttgg gatatgatta ggaaatcggc catctggttc caaaaattgg
     7141 gaacctgttg aatccgcacc taagctattc aatacttttt cagcaaagaa tccaccagca
     7201 ccatttccgg catcaacaat gattttccaa ccatttagtg gtttgctttc tagtgttcca
     7261 atcccctttt taatttttgt gactaaatct tgcgcataag gtgtcaaaag gtctgctttt
     7321 tctacgcttc cagtttgttc gctttttatt ttttgctgct gtgataggat aaaagcaata
     7381 tcttcttttt ctgctcctcc ttctgaggta aagaatttta ttccattata ataataggga
     7441 agatggctag cagtcagcat aaccgcagca tcgcacgaga actgttcaaa ttgagtggac
     7501 ataaacatag caggcgtagt agctaattcg aaatcgatga catgtatccc ttgttctttc
     7561 agactttgga tcaacgcctc tttcagtgct ggtccgctta tcctactgtc atgaccaatc
     7621 ccaatcgtcc attttttatt tggatcggtt gatttcttct ttttctttat ccagtttgct
     7681 agtccccagc cgatcttttt taccatgtct gtcgtcaagt ttacttcata tccttcaact
     7741 ggtaatgcga ttcctcgaat atccgatcca ttttgcagcg ctttcatatc tttcatataa
     7801 aagtcctcct catttattcc ctcatttttt ccagcttttc tgcaaatcgc tgtgcttctt
     7861 cttctgagcg gcaaataata atgaatgtat ctacaccggc catcgttccg acaacttcag
     7921 ggtaagccac ttcatctagc caattcgtta ccacatcggc accatttcgt tcagtcaata
     7981 cgataaccat gaactgaaca gactggatac gcaaaacctc gcgtctaatt gctgtacgca
     8041 aacgttcttc atttaaagaa acagatggct ggttaaataa tgtatagcgt actattttgt
     8101 tttcattttg actttttact aacttcattt ctcgaatgtc tcgagaaatc gttgcttgag
     8161 tcacatcggc gcctgcttca tgcagccgcg caagcagctc ttcctgtgtc ccaataggtt
     8221 gttctgtaat gatctggcgg atcagtgctt gtcgctgttt ctttttcata ttagacacct
     8281 ctcaatgttg attatagcaa aagataagta atatttcttc atattttggt attttttact
     8341 tttatttttt gttttcattc aggttgctaa cctttttcta ttttaacacg caaaatcgtc
     8401 ttcatttttt caggtgctga ttttcttgga tcgctgatgt aaatctcttt gtgttcttta
     8461 gaagctcttt catagccttc ttttgcgatg aatgcttcta atttctcaaa cgttgctggt
     8521 tcttcggcat agggcccgac gtgtaagatt tgggcacaaa gaccttcttc catctttttg
     8581 aatactactt gttctttcaa gtcttccgga agtttgctag aacgctgaat ggcttcttgt
     8641 gctatcgctt ctgtaacaaa gtcaggctgt cggatcatca attgataaga aaaatgttct
     8701 tttttcatca ctggttcatg caaatacttt tcttgcagtc cccattgtcc ttccagtgga
     8761 tagacagtat acatctgata atcaggaatc agccaatttt ttttaggcga catgcgtatt
     8821 gcatagctga ctgcatatag acaggctact cttcgtttaa agtcttcctg attcgggtcg
     8881 ccgatccctc tgatgctaaa gaatgatttt ttaggaacct ctagtatttg cgggcttttt
     8941 ttcatactat agctcttgtc tttacgccat tcaatttttt ccatttttct tcctccgcga
     9001 aattccattt agttatttat tatcatacct ctttttgagt gacttggcta atcgtgttga
     9061 cactattttt cagtttgtgc tagaataagt gaagtaaata aatcgtacag ataacacgtt
     9121 tcggcgtgtc gagagagagg cggtttctat ttttataata gaaatcactc tcttttttta
     9181 cgaaattttt tagaggtgat gtaaatgaca aaacaaaaac agctgctttt agtacctgca
     9241 gtaattgcaa cagggatgat gtcttttgcg ggcgtattga tcgagacggc catgaatgta
     9301 actttcccaa ctcttatcag acagtttgat ttaacgactg cacaagtcca atgggtaaca
     9361 acgatttatc ttttgatgat ttcgatcatt gttccgctgt ctacttattt gaatcgcaat
     9421 tttagtctca aaaaactctt tttagcttca aatctgcttt tcttggcagg tataatgatc
     9481 gatttcttct ctcctacctt catggtccta ttgtttggtc gattgctcca aggtgcagcg
     9541 acaggtatcg ctcttccgtt gatgttccat attatcttga catttgcccc cctcaatcga
     9601 cgaggcgcga tgatgggtgt cggtactttg acaacggcca ttgctccagc aattggcccc
     9661 acttatggag gcattatgac ttcacatttt acatggaatc atatcttcct gtttcttgtg
     9721 cccgttttga ttctttcttt gattatcggc tggtttgcta ttcccgagat ggcagtacaa
     9781 aaaagtggtt atttggattg gataagcgtt ttaggaattt gtcttttgtt tagtggaagt
     9841 ctaacatttt tgagtacgtt gggaacagtt tccagctgga ttgctttaat catcggcggt
     9901 attggctggt tcctttttta ctatcgaagt aaaaaagtgg agcatccact gatccgactg
     9961 tctattcttt caaataaaac attccgcttg tttttgattg gcttcttagt ttatcagttt
    10021 ttattacttg gtgtatcttt tgtcttgccg aatttccttc agatcgttca aggaagtagt
    10081 ccttttgtcg ctggattagc gatgcttccc ggcgcagcgg ttggtgcttt gctttctcct
    10141 ttttccggga aaatgctgga tcaatatggt ccgaagaagc caatttttgc tgggctgatt
    10201 ctttctttga ttggttggct agcattattc ctactcatag gacacgcttc agtgggtgta
    10261 ttgattgctt gtcatgtgtt ttatatgatc ggtatcggat tatcttacag caatatgatg
    10321 accaccggaa tgaatgcact gaatgaagaa ctacaaggag acgggaacgc aatgttcaat
    10381 accttgcagc agttttctgg cgctgtggct acttcattag tagcggtcat tatcaattac
    10441 gtccagcatc atacttccca taactatgaa gtgtctacta cattaggatc aaaagcagca
    10501 ttaggcgtct tgttgctgtt gcttctcgta agctttgctc gattcgccta ttatctgttc
    10561 tttgctaaaa aagcgtagat tccatatacg gcaggtgttg catctgccgt ttttttgtgt
    10621 gaaaatggtt gtttgtaaaa ggaggctttt ttatggaaaa aattgccatt atcggtggcg
    10681 ggatcattgg tatgacccta gccagttact tagatacatc aaaattcaat gttgctttat
    10741 ttgatgaagg gacaggacag gcaactaaag ctagcgctgg gattatctcc ccttggttgt
    10801 cgaaacgcag aaacaaacaa tggtatcgtc tggctaaaga cggcgctgct tttttcccta
    10861 aacttataaa agatttccaa cttgatcaaa cgatttacgc acaatcaggg acacttttgc
    10921 ttcgacctga aaaagattta gctgaattgg ctgttcttgc cgagaaacga aaagaagaag
    10981 cgccagaaat tggaaacatc gaatggcttt cacctgaaca gacatctcaa gcacttccgt
    11041 tattgaaacc agcagtttca ctgcgtatca gtggtggtgg tcgtctggat ggaaaagcat
    11101 atttagaaca tcttggtcag cgtttagcac aaaaacaaat ggagcagatc caggcaaaag
    11161 tcactttgca taagaagagc gattcttggc tcatcaaggg accgtttgga gaatacacag
    11221 ctgatcgtgt aattttgaca cctggcccgg cacttaagcc tttattacaa gaattaggct
    11281 atgctgcaga tatacgtccg caaaaagggc agctcttagc atttcagaca tcttataaga
    11341 tgagtcaaga ctggcctgtt gctatgcttg acggagaagc tgatttcatt cctttcatgg
    11401 atggaaagat ccttttaggt gctacccatg aaaacgatca aggctgggat ttggctccta
    11461 ctagcgaagc ttataaggga ttgactaaga gtacagaaca gttcttgact gatccagatc
    11521 agataaaaaa ctggccatac gagttccgtg taggtacccg tgcttatacg tcagattttt
    11581 ccccattttt cggcgtactg ccagatgatc caagcttact ggctgctagc ggtctaggct
    11641 cttctggctt gaccacaggt ccttatatcg gctatctatt agccaacttc ttaaatactg
    11701 gtcattggcc tacggaagat tatcaaaagg acatctccac ctatattacg aaaaatccat
    11761 catagaaaaa cagctttttc aagtaaggat cccgagcgat attgcgcatg gattacttct
    11821 tgaaaaagct gttattttag ttcaatttct gaatcaaatt ctccaaactt tcttttgctt
    11881 catctggcaa gagatctttt cctatctgag cttcaatgaa tcgtaaacga atatcaagtc
    11941 gttgtttcac cagattttta taggacgtat cctcaaaaga aacaggaaaa tctggtatag
    12001 gtaaatagtg gatgtcttca aatggaccaa acgacttgaa ttctgccgtt tgttgcacga
    12061 ttctttcaac gattgacaat gtcgtttcag gtttgatttt tttatcatcg aaatatccag
    12121 tattcaggac atagcaggct gtttgctgtt tcaaaaacaa ctctcgaaaa gcttgatagt
    12181 cttccctaag aggatagaca cggaaaggat tagcaaatgg ttcaatgact agctcatcta
    12241 gctgtctttt tgtagtgata ttttccgcgt ctgatcgttt tgttgctaat gttgcaccaa
    12301 aagacgctgc taaaactggg tcattgatct tgataattgg cggaagcgaa tcatctttca
    12361 tgatccaaaa aacagcatcg atcttttcgc taagatgatc gactcggtcg ggtgtcgcat
    12421 aacgtgattt gactgtccgc ccatttccgt ttcgtatatc tcctgttact aggacttttt
    12481 ctcctttact tgtacatgtc acgcccacat tctgacaagt aaggaaagaa gaaatggccg
    12541 gatcatcaga cggatagtct tgtgttttat caaagtaaga aggttccaag gcagtagcaa
    12601 aaccattttt tcgagaaata acgaaagcat cgtcatgcaa gatcgaaaca gagtgacctt
    12661 ccgtatgttt tgctaaggta atcgttgatt ttccagaacc ggacaaccca aatacagcca
    12721 tcgtataggt ctggtcatta ctagcatatt gtttcatccc accgtggcag gcaataaagc
    12781 cattgcgatt tcccaatgcc caagcaagcg tcaaagtcgc tttttttaat tctccaaagt
    12841 aacgtaatcc tagcacagcc gctgtattat ggagagcatc aaacaaaatg agtccatttg
    12901 gaaatgtttc atgtgtccat tcgggatcac aaaagatata aagatctccc tcatcaaagg
    12961 aaacagactt ttgataagtc tctaagatct tcgaattcgc tggctgaaaa ttcagcaaat
    13021 aagaatacaa attgttctca aatccttctg gaatcagcaa atgactttgc acagaaaatt
    13081 cttcagatag gccaacgatt acttttgtat ggtaaaactg gcgcttgcga ctttgataca
    13141 cagcttctct taaaattttc tcgtatttgc tttgttcctt gtctaagtcc tcaaagatcc
    13201 gccgagcact tgctgttctt cccacaatgc ttccatcatt gaatactagt gtcctaacat
    13261 cagctggtaa atctagttct tcagcatgtg agattgttaa atctgtgatg atcgttcctg
    13321 gactcccttt tgctagttga taagctgtct tcctatcaaa aacttcatga acattattac
    13381 cgtaaaatgt cgtttctaca atcgatcgaa tactggataa cagtggattt ccacttgtga
    13441 tttcgtttaa ttcgagactc tcttttgtac tcatggctcc tcctcattcc ctaaacaaaa
    13501 aaacgttttc tttattatac attattcgag tttttatttg tactgctgcg ctgtgggaag
    13561 caaacgagtt atttttcaca caaaaaaacc gagaacttga ataaacaagt ttctcggttt
    13621 catcattttc cttttatcgg cttagtacca gccgtttgct aaccagaatg ttttagcagc
    13681 atcccatgaa ccataacgag atgttacata ttgttctgct acacgttctt gattggcagc
    13741 tgaatagtcg ccgtttaagt atgaagcatc taattgataa cggccgatgt aacgtccgtt
    13801 agtagctgtg tatgaaccgc ctgattcttt ttgtgcgatc cattcttttg cagagcttga
    13861 agttggcgct gttgcagcag ctggggcagc aggagctact tcaactgttt caacaggtgc
    13921 aacgtatgta tgttcttgcg ttgctgtttc agttgtagat gctgtatttt ctgttgtttt
    13981 gttttctgtt gttgctgaag aatcatttga agttgggatt gttaattgtt caccaacata
    14041 aatgcggttg atgtttgcga tcgaattttt ttcagcaatt gcatcgatca ttgagttgtc
    14101 tcctgcaaat ttttgtgaga tcttagataa tgaatcacct gattttactg tataaacttc
    14161 atcagcgtga gcatttgtag ttcctacaaa cattgcagta gcaccagcag caaaagttgt
    14221 acctaaaaca attttcttaa atgaattcat attaaactcc tttttttctc cgttttttat
    14281 tctttcgacg ctattaactt tatcatttag aaatatttca taggtaaaag aaacatgaca
    14341 tttaatgaca aaataacgaa tta
//
LOCUS       DAXQKX010000063        14307 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.065, whole genome shotgun sequence.
ACCESSION   DAXQKX010000063 DAXQKX010000000
VERSION     DAXQKX010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14307)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14307)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14307
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.065"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            265..966
                     /locus_tag="ACF3MF_002218"
     CDS             265..966
                     /locus_tag="ACF3MF_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HFE3928166.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            963..2084
                     /locus_tag="ACF3MF_002219"
     CDS             963..2084
                     /locus_tag="ACF3MF_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HFE3928167.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            2099..3331
                     /gene="pepT"
                     /locus_tag="ACF3MF_002220"
     CDS             2099..3331
                     /gene="pepT"
                     /locus_tag="ACF3MF_002220"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HFE3928168.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            3463..4371
                     /locus_tag="ACF3MF_002221"
     CDS             3463..4371
                     /locus_tag="ACF3MF_002221"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFE3928169.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            4406..4678
                     /locus_tag="ACF3MF_002222"
     CDS             4406..4678
                     /locus_tag="ACF3MF_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HFE3928170.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            4689..5735
                     /locus_tag="ACF3MF_002223"
     CDS             4689..5735
                     /locus_tag="ACF3MF_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhN family protein"
                     /protein_id="HFE3928171.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            5986..8595
                     /gene="clpB"
                     /locus_tag="ACF3MF_002224"
     CDS             5986..8595
                     /gene="clpB"
                     /locus_tag="ACF3MF_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HFE3928172.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQPNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(8746..9432)
                     /locus_tag="ACF3MF_002225"
     CDS             complement(8746..9432)
                     /locus_tag="ACF3MF_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928173.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(9410..9904)
                     /locus_tag="ACF3MF_002226"
     CDS             complement(9410..9904)
                     /locus_tag="ACF3MF_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HFE3928174.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(9924..11144)
                     /locus_tag="ACF3MF_002227"
     CDS             complement(9924..11144)
                     /locus_tag="ACF3MF_002227"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFE3928175.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            11291..13126
                     /gene="lepA"
                     /locus_tag="ACF3MF_002228"
     CDS             11291..13126
                     /gene="lepA"
                     /locus_tag="ACF3MF_002228"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HFE3928176.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEDEPKK"
     gene            complement(13220..14307)
                     /locus_tag="ACF3MF_002229"
                     /pseudo
     CDS             complement(13220..14307)
                     /locus_tag="ACF3MF_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
BASE COUNT         4628 a         2619 c         2957 g         4103 t
ORIGIN      
        1 aaatgaattg aaaatcggtg acaaagtcca atttacatta gttgagatgc cgatcatgac
       61 gatgtctatc ccaccgcaag ttcctggaga ttcgattatt gatgtttcat tgaacaaata
      121 accaataaca ttttttcaaa aataagaaaa tgttgtttta tagaacgaaa aggtatattt
      181 tttaaggaga tatgggaatt tttttattcc tagtctcctt attttatttg gaaaatgcta
      241 taattatcta gaaggagtga agctatgaac catttagatt tatctcagcg cttagccgca
      301 gtgggtgact ttgtccctga atccgctcgt ttagcagaca ttggatcaga tcacgcttac
      361 ttacccgttg cattgatatt aagaggaaaa atcgaatatg cagttgctgg tgaagtcgtt
      421 caaggtcctt atgaatcagc acgtaagcaa gtcaaaaaag atggattaga agaccgtatc
      481 accgtacgcc ttgcaaatgg tctagatgct atccagccac aagatggtat tacagctgtc
      541 acgattgcgg gtatgggagg ttcactgatc cgagatatcc tagaagctgg caagttgaat
      601 caacgcttaa gcggacaaga acgtttgatc cttcagccaa acatcggaga gcgtacatta
      661 cgatcttggc tgcaagaaaa tcagtataaa atccaatcag aaaaaatact tgaagaaaat
      721 aaaaaaatat atgaaatcat tgtagccgaa aaagaacaaa aaccagttac ttacaatgaa
      781 atggagctga tgttcgggcc atttctgctt gaagagaaaa gtgagatctt caaatcaaaa
      841 tggacaagag agcttcaaca aagaaaagct atccgtgaac agctcaaaca agcagctaat
      901 caagaggcac gtcaaaaaca aatcgagcag gaaatccaaa tgattgagga ggttttaaag
      961 ccatgacaat cagcggacgc actttcatcc aaaagtttga aagctattgt cctcagtggc
     1021 tagctgaaga aggagaccca gtcggactgc atatcggaac attggataag ccaatccaac
     1081 gagtaatgat gacattagac gttcgtccag aagtggtcga agaagcaatc aagaaaaaaa
     1141 tcgatttgct gattgctaaa catcctccaa tctttcgtcc tgtaaaacgg ctggttactg
     1201 atcagccaca agaaaaaatg tatgcagatt tgttgaaaca tgatattgcc gtctatgcag
     1261 cacacacgaa catggatatt atttgggatg gactgaatga ctggttttgt gaacttctcg
     1321 gtattgaagt ggagagttat ttagtaaaga ctcatgagat tcattataaa aaactggccg
     1381 tttatgtacc tgtggatcat gcacagaaaa tgcgtgaagt attagctgca gctggtgctg
     1441 gtacacaagg tgattatacc ggtacaagtt ttacctcgat tggacacggt cgatttactc
     1501 cggaagctgg tgcacaacca gcgattggga aagtagggaa gacagaacaa gttcaagagg
     1561 caaaagttga ggttattttg ccggaaacta tcgaaaaaca agtgattcaa gccatgcggt
     1621 cagctcatcc ttatgaggaa cctgcttatg atcttttcgc tatagatgaa ccagtcgaaa
     1681 tgtttgggtt aggacgagta ggtgaattgc cgcaagaaat ttctatagag gcatttgtag
     1741 aacaagtaaa agaagcgttc caactagatg gactgagaat agtccagcca aaaaatgcaa
     1801 aatcctctgt gaagcgcatt gcgatttgcg gtggaagcgg tgaaaaattt tatccgcaag
     1861 caatcgccca aagagcagat gtctatatca cgggagatat ctattatcat acggctcatg
     1921 atatgcaaag cgctgggttg attgcaattg atcccggtca ttatattgaa tcgttatgca
     1981 agcaacgatt tatcgagaaa tttgaatctt ggaaacaaga agaaaattgg gatattaact
     2041 ttttcgtttc tgaaacaaat acaaacccat ttcaatttaa ttaaaaggag agaatactat
     2101 gtacgaaaat cttttgccac gttttttacg atatgtcaaa acagaaacac gctccgatgc
     2161 aacaagcaaa acgactccat cgactcagac acaagttgct tttgcgcaag aattgaaaaa
     2221 agaattagaa gagttaggct tagctgatgt tttctataat gaagataacg gattcgttat
     2281 gggaacatta ccaagcaatg ttgatcatga agtgcgttcc attggattta tttcccacat
     2341 ggatacagca gattttaatg cagtaggagt caatccacaa atcattgaaa actatgatgg
     2401 cgagtctacg atcgtactag atgcggaaga acgctataca ttgaatacaa aagattttcc
     2461 aaatttgaaa aattatgaag gccacacatt gatcacaaca gatggcagta cattactggg
     2521 agcagatgac aaatcaggga ttgcggaaat catgactgca atggagatct tgatcaataa
     2581 tccttctatc cctcacggta ccatcaaagt ggcttttggt cctgatgaag aaatcggtgt
     2641 cggagcggat aaattcgatg ttgagcaatt cgatgtagat tttgcttata cagtcgatgg
     2701 tggtccttta ggtgagttgc agtatgaaac gtttagtgct gctcaagcaa atattacgat
     2761 ccaagggaaa aatgtacatc cagggacggc aaaagataca atgatcaatg ctctacagtt
     2821 agcaatcgat tttcataatc agcttccagc cgatgaagtt ccagaaaaaa cggaaggata
     2881 cgaaggtttc ttccatttga tggcattgga tgggaatcct gaagaagctt ctatgagtta
     2941 tatcattcgc gatcatgatc gtgaaaaatt cgaagcacgc aaagcacaaa tcacacatat
     3001 ccaagaagag ttgaatcagc gatttgatca agaacgaatc aaagtagata tgtatgatca
     3061 atattacaac atgaaagaaa tcattgaaaa agatatgagc atcgtggaat tagcgaaaca
     3121 agcaatgatc gagcttggta tctctccagt gatcgaacca gttcgtggag gaacagatgg
     3181 ttcaaaaatc tcttacatgg gtattccgac gccaaatcta tttgccggag gagaaaatat
     3241 gcacggacga ttcgaatttg tttctttaca agtaatggaa aaagcaacag acgtgattgt
     3301 aaaaattgca gaattgaaca caaagagtta aaatcgaaaa agaacagctt atgacaaggc
     3361 gttcgtccca atgatggaat gtcatctgtc taaggctaaa gggcaggaca atggaattgg
     3421 ttgtcccgcc ctcttttttg aagagtaaat aggaggtaaa gaatggaaaa gctgctagtt
     3481 ttttataaca aaagttcagg gaaagatgag ggtgagaaat tagcacgctg gtttcaagat
     3541 tatgtaaaag aaaagcagcc agaattatat gtagaactag ctgaaactgg cccatcgatt
     3601 gatgatgcgg aattagtcaa gaaagcagaa gccatagaag ctgatacttt agtaattata
     3661 ggtggagacg gcacgattca tcatatcgtc caagcgttcc aaaaaacatt atctcaatac
     3721 catgtcggat tacttccagg tggaactgtc aacaaccttg cacgtgttct tgagattccc
     3781 ctcaaaaaag aagaagctgc tgacgtgatc ctggaaggca atgtacggaa aatagactat
     3841 ggtcaagtca atgatgaagt cattatctct acactgacaa tcggaatctt agcagataca
     3901 gcagtttgga tcagtcaaga agaaaaacag cgttacggct cgtggatctt tatcaagaag
     3961 ttttttaagt tattgctgaa gaagaaaaaa tatcatttgg atttagaaac agacgaggag
     4021 cattggaaag gaaaatccca actgttgaca gtcacgatgt ctaactccgt gggcggtttt
     4081 acaaattttg acgactcagc gaccctagat gatggaaaat ttcatgtaac gatcgtacct
     4141 tccttagata ttttccgatt tattttttat ttgcctagaa tcatgagagg caaattctat
     4201 acgatccccg gcattactta tttcacagcc aaacgcatga aaatccaagc gcaggaaaaa
     4261 tctgtgggca ctcgaacgga tggagacacg acagatgatc ttccagttga attatctgtt
     4321 gtatcaaaag gattaacagt ttattcacca aagaaagaag aaaaagctta gaaatagtag
     4381 ttaacagaaa gttggaagaa gagtaatgga tgtattgtta cacaatcctt tgtggtttta
     4441 ccttttcatt gtgaattttt acttattttg tctgatgggg tatgataaac atcaggctag
     4501 aactagcggc tggcgtgttc ctgagaataa tttgatattt gtcagcctgt taggcggtgg
     4561 tttgggagga ttgatctctc gaaaagtttt ccatcataaa actcggaaaa agaagtttac
     4621 tataggattc gctgcaggtg tacttgttga tttgattctc atttattttt tccattaagg
     4681 agcaggagat gtcgtctaaa ggaacgaaaa ctaaaatcat tctgaatctg cttttgctga
     4741 ttgtgatttt tgccattatt tattatttaa tcaatcaatc atttgcagat atctttgccg
     4801 aattgctgtc taccagtgtt gttgttttgg cagcggctgt tatattaggg acagtttacc
     4861 aaatcgctga agggcgctca atcaaagaaa ttgctgaacc tttcgcgccg aattttacaa
     4921 cgaaagatgg gttcttgacc tctagctata ttgcgtttta ccgaatcgtt tcgtttggta
     4981 caggaacgct gatctcggag atttattttt ataacaaaaa aggaatgaag ctatcccagg
     5041 gagcaggggt gacagcactc catatgatta tgtacaaact ggcagtgatc acttatgcat
     5101 tagctggctt ggtcatccaa ttctctcttt tttattctaa tggtccatca atgatctggt
     5161 ttatcatcgc tggtatcctt ttgacgatcg tgattgttgc ctttttattg gcgatgtccg
     5221 tcagcttgaa tgttcaaata ttttttgtca gcttatcgaa taagttattt aaaagtgagc
     5281 gtttgcggaa atgggtggat acatgcaatc agcagatcta ctctttaagg gaaacggtcc
     5341 aaaccattat ccaagacagg actgcgctat tgcggattta tctatggaat atgttaaaac
     5401 ttgtattttg gtatgtactt ccttatttga ttctgattga aaaccatcct aaaatagatt
     5461 ttctactgac catttcgttt atcagctttg cagtagtgct ttcaggggtt attcctacgc
     5521 ctgctggtat tggttccttt gaatttgtct atttgttatt attcagacca gttgttggaa
     5581 cagttgacgc agtttcttcg cttttactgt atcgtttcag ttcctttatc ttgccatttc
     5641 tctatggatt tgtgtatgtg attgctgaac ggcgaagagt gatcaaagaa gaaataatag
     5701 aagtaaaaaa agagaataaa gaaaatcaag ggtaggtctt ttataagatc tacccttttt
     5761 atcaaatcaa agaaaaacgt tatggataag ataattttac gtttgtttgg ctcttttttt
     5821 atatacatac aatcaatttt gtttttttaa gatttatata agtcgagaaa aaaagtcaaa
     5881 aaactatgtg tatattttga ccaaaattga ccaaagcgat ataatagttt ttgtaaagat
     5941 caaagaaata agtgatctta cctttaatta ggagggtata cctgtatgaa tattgagaaa
     6001 atgactacga cgcttcaaga agcgattgct gaagctcaac agattgcggt cactcgaaaa
     6061 catcaagata tcgacattgc ccatgtatgg aaaatctttt tacaacctaa tcattttggt
     6121 cgaaatttct atacggatgc cggattggat gtcgaatctt ttgaacatga aattgatcgt
     6181 ctactggatg agtatccagt tgtttctggt ggaaacgtcc aatatggaca aaacctcagc
     6241 cagaatttct ttcgattatt gaatgaagca gaccaaatac gtgaaagctt cggcgacgag
     6301 tttctttcaa cggaagtcgt tattttagcg ttgatgaaat taaaaaatta tccgttaact
     6361 gtttatttga ataaaaacgg attatctgaa aaagaattgc gtaaaaacat cgaagagatg
     6421 agaggaggag aaagagtgac ctcacaaaac caagaagaac aatacaaagc attagaaaaa
     6481 tacggcgttg atttagtaca gcaagtcaaa agcggaaaaa tggatccaat catcggtcgt
     6541 gatgaagaaa tccgtgatgt catccgtatt ctttcacgaa aaacaaaaaa taatcctgtt
     6601 ctgataggag aacccggtgt agggaaaacg gcaatcgttg aagggcttgc tcaacgtatc
     6661 gtacgcaaag atgtgcctga aaatttaaaa gataaaacga ttttttcatt agatatgggt
     6721 gcattgatcg ctggagcaaa attccgtggt gaatttgaag aaagactaaa agcagtcttg
     6781 aaagaagtca aaaaaagtga tggacgtatc ctcttgttca tcgatgaaat ccacaatatc
     6841 gtaggggcag gaaaaacaga aggaagtatg gatgccggaa atctgttgaa accaatgctt
     6901 gctcgcggtg aattacattt gatcggtgcc acaactttag atgagtaccg tcaatatatg
     6961 gaaaaagaca aagcgttgga acgtcgcttt caaaaggtat tagtcaaaga accaacagtg
     7021 gaagatacga tcagtattct gcgtggatta aaagaacgtt ttgagatcca ccatggtgtt
     7081 aacatccatg acaacgcatt agtagcagca gctactttat ctgaccgtta tattactgat
     7141 cggttcttac cggacaaagc aatcgatttg atcgatgaag ccagtgcaac gattcgggta
     7201 gaaatgaact ctatgccaac ggaattagat caagttacta gacgtttgat gcagttggaa
     7261 atcgaagaag ctgcactgaa aaaagaatca gatgatgcaa gtaaaaaacg cttgaaaaat
     7321 ttgcaagaag aattagctga acttcgtgaa gaagcaaatg cgatgaagat gcagtgggaa
     7381 acagaaaaag aagaagtcaa ttctgtttca gcaaaacgtg ctgaaatcga taaagcaaaa
     7441 cacgaattag aagatgcaga aaataactat gatttagaac gcgctgctgt attgcgtcat
     7501 ggtacgatac ctcaattaga aaaagaattg aaggaattag aagctaaagc aaaagacagc
     7561 gagattaaga tggttcaaga gtccgttacc gaaaatgaga ttgctcaagt cgttggcaga
     7621 ttaacgggta tccccgtaac gaaacttgta gaaggtgaac gagaaaaact aattaaattg
     7681 aatgaaacac ttcataaacg agtgattggt caagatgaag cagttgatgc ggtcagtgac
     7741 gcggtaattc gttcacgggc tggattgcaa gacccaaatc gtcctctagg ttctttcctt
     7801 ttcctaggac caactggtgt cggaaaaacc gaattagcga aagcgttagc tgagaacttg
     7861 tttgactcag aagatcatat ggtacggatc gatatgagtg aatatatgga aaaacatgct
     7921 gtgtctcgtc tagtcggagc tcctccaggc tatgtaggtt acgaagaagg tggtcaatta
     7981 acggaagctg tcagacgaaa tccttataca atcgtcttgt tggatgaaat cgaaaaagcg
     8041 catcccgatg tcttcaatat cttgttacaa gtcctagatg acggacgctt gactgattca
     8101 aaagggcgag tagtagattt caaaaatacg gttctgatca tgaccagcaa tatcggttca
     8161 cagttactgc tggaaggcgt gactgctgat ggaacgattc cagaagcagt ggctgaacaa
     8221 gtcaacacgc tattacgtgg aaacttcaaa ccagaattct tgaaccgaat cgacgacacg
     8281 attttattta caccattgag cctagacaac gtgaaaggaa tcgttgacaa aatggtggcg
     8341 caattggcac aacgtctgga acatcaagaa atcctgctga caatcagtga tgaagccaaa
     8401 acgtggattg ctgaaaatgc ttatgaacca gcatatggtg caagaccatt gaaacgattt
     8461 atcactaagg aagtagaaac accactagct aaagaaatcg ttgcaggaca tgttatgcct
     8521 aaatcaaaag taacgattac tttacttgat ggacaacttc atttcaaaac agaagagcta
     8581 gaagaaatcg tctaatcttc cattgagact ataaaagaaa aaaggggtct gacacaacta
     8641 gtgtcagacc tccttttttc aaataaacag tgttccagaa gtagtttctt cgaaaaataa
     8701 gccgaaattt cttgaagctg cccgcttctg tcacaacctc ttttattagg tatttttcac
     8761 tttttctaat ttataacttt caaagtaacg ctcatctttt ttactttgag accatgcaaa
     8821 caatcccatt aaggcagcac ctatcgtatt tgtcagcaag tcgcccatcg tatccatcaa
     8881 tgctgctcgt ccgacaaaca gtgtgccatc agaagcagca aaacgttgaa gattcatgcc
     8941 taagaactgg tcgcataaga attcccagaa ctcccaaaac acgccgcaaa gtccagcaaa
     9001 cgcaaagccg aataagagga acaaccaagg actggttttt gatatctcag catctttcat
     9061 caagtaacca atcaatccat agccaagagc tgtcaggacc attggactca ccgcatgtaa
     9121 gattttgtcc caaaaagaga tgatactgat caaatgcatc cctgtgccta aaaagacaga
     9181 gatgaacaag aaaaaccagt aaaacaaaac gattgctgct ggtattttaa gtttgaaaac
     9241 tttcaaaatg acttgtggca tgaaaatcaa tgcaatccct aataaagatt ccacgataaa
     9301 tgtgattcct tgagaagtcg aatatttttg tgtgataaat tcataaaaat tatagcagac
     9361 aacgaataca ccaaaagcaa gtaaagctat ttgcaccttt ttgatttctt taatcactga
     9421 aagtccctcc atctaaaaat ctttttactt ctgaaagcaa ctcaatttct gaagaaacca
     9481 cttttccgtt caatttgatc aaacctattg tatataagtt caggtagtga aattgatttt
     9541 cagctgtttc ttgtagtgca gcgatttttt tcgggtgggt tccgccttgc tgtcgagtat
     9601 cagtatataa gccgatcact gggatgcctt tcgcataagc cacaccgatt tccgatgcta
     9661 ccccggcatc gatcgtcagc ccatctagta aagcaatcat taaatcacta gccaacactt
     9721 tttctgtgtc agcaagagca atcattcgac tgtctgcata agcagttttg tcattgattg
     9781 cttcattttc ttgaggaaga tagatcgaaa gctcagaaga gagctctctg atttctttaa
     9841 ctaactgttg gttatataac aaatcacttt tagcaaacat tggtgcggca aaataaattt
     9901 tcatctaaac atcatccttt ttatcaaaaa taatcgctaa agtaagcttc catgtttgga
     9961 atgatacgct ctagtgactt cagtgtttct tcatctgttt ctaaccgttc gattcttgcc
    10021 aaataagaag cacggcgata attcatcatc aagcaagtca atgtttggat atccagtcga
    10081 acggattttc ctataggttc atttaagaca cggacttgtc cctgttcatc ccatgttaaa
    10141 gcgaagacac cattattcca aggagcgaca ggatcttcaa tgatgaaatg aaaagcatca
    10201 gctgttccaa caaacggaaa ccgttgaagg aattctttta catcaacgat ccgagccata
    10261 aaatatggtt cgatctgctc tttgatctga ctatcttcaa tcaaaaatgc taaaggctca
    10321 tttttataaa tatctccatg tacccagtag atcatggaaa aatgtgcgga aataaagttc
    10381 cataagccat ttcgagcttc ttgatcaaga tagaacattt cttttacgtg aaatatttct
    10441 tcagctaccc agtagaacag aacacctctt ggttcatggt tgctatcgta gtagacagcg
    10501 gctgtgcgct catcttcatt ttcgaaacgc caatactctt cccaatgaaa atcactgcgg
    10561 aataaagcac catggttttg ttgggcaaat ttgtcataaa cggaaaatac gtctggatga
    10621 tcaactggta atcgctcaac cataccactt actgggattt gtttaggtag ctgtgtatct
    10681 ctgattttaa aggaaagttt atcagacatg atttcccatc ctttacgccg atagtagggg
    10741 atactgtaag gatacaaata agagatccat tgcttattct tgcgcatatt atccaatgca
    10801 acgataatta gatcttgcat caatccatgg ttagcatatt ctggataagt tccaactcca
    10861 gtcacaccac ccattttata acgtgcaccg tgaatattga cttcacaagg atagatagcg
    10921 atttgagaga tcagtttatt ttcgtggaac catccgaaca ctttcgatac ttccaaaatc
    10981 ggttttttgg aacggataaa agctcgttta ttctcaaacc cgctttcctc gatgtctgct
    11041 tcagtcactt ggaacacata ggaaagcaat tcattgaatt gatcgatatg ttcttgagtg
    11101 accggtttta attcaagatt ttctctaaaa tctttttgat ccattttttc atctccattt
    11161 attagcttga taacagtata gcaaaattct acaaaaaaaa cttctatagc tgactaatta
    11221 aaaactcttt aaattactgc ttttcgttgg tataatggaa agtgctgatt atatgaaaag
    11281 aggagacgct atggatataa agaaaatgaa agaacgccaa gagcagattc gtaatttttc
    11341 gatcatcgct catatcgacc atgggaaatc tacattggcc gatcgtattt tagaaatgac
    11401 gcacactgtg acgtctcgcg aaatgcaaga tcagctgtta gactcgatgg atttggaacg
    11461 tgaacgtgga atcacgatta aattaaatgc tgtagaactc aattacacag cgaaaaatgg
    11521 agaaacatat atctttcact tgattgacac cccagggcac gtcgacttca cctatgaagt
    11581 ctctcgaagc cttgctgcct gtgagggtgc cgttttagtg gtcgatgcag cacaaggaat
    11641 cgaagcacaa acattggcca atgtttattt agcgttagac aatgatttgg agatcctgcc
    11701 agtcatcaat aaaatcgacc tacccgcagc agatcccgaa cgtgtccgtc aagaaatcga
    11761 agacgtaatc ggaatcgatg ctagtgaagc tgtattagcc agtgccaaat cagggattgg
    11821 gattgaagat attctcgagc agatcgtgga atatgttcct gcaccaagtg gagacttaga
    11881 tgcaccgcta aaagctttga tctttgactc tatttatgat agttaccgcg gtgttgttct
    11941 aaatgtccgg atcacggacg gtatggtcaa acccggagac aaaatcaaac tgatgagtaa
    12001 tggcaaaaca tttgatgtta cagaggtcgg ggtcttctcg ccaaaagcag ttgctagaga
    12061 ctttttgatg gtcggtgatg tcggttatat cacagcaagt atcaaaactg tccaagatac
    12121 acgagtaggg gatacagtaa cgttagcaga caatcctgcc gctgaagctt taccaggtta
    12181 ccgaaaaatg aatccgatgg tttattgtgg tctttatcca attgatactt ctcgttacaa
    12241 cgatttgcgg gaagctttag aaaaactgca attgaatgat gctgctttac aattcgaacc
    12301 agaaacctct caagcattag gttttgggtt ccgctgtgga ttcctcggac ttcttcatat
    12361 ggatgtcgtc caagaacgct tggaacggga attcaatcta gaattgatca cgactgcacc
    12421 atccgttatt taccatgtta ataaaacgga tggtacgact gctacagtag ataacccggc
    12481 agattttcct gaacctgtaa cgattcagga tgtagaagaa ccattcgtca aagcacagat
    12541 catggtccca aatgattttg tcggtgcagt aatggaactt tctcaacgaa aacggggaga
    12601 attcattacg atggattatt tagatgatta ccgagtaaat gtcgtctata atattccgct
    12661 ttctgaaatt gtctttgact ttttcgacaa attgaaatca agcacgaaag gctatgcctc
    12721 attggattat gaaatgtctg gttatcaaaa aagcaagtta gtgaagatgg acatcttgct
    12781 gaatggagaa aaagtcgatg cattaagctt tatcgttcac cgagactttg cctatgaacg
    12841 tggaaaagca atcgttgaaa aactgaaaaa actaatccca cgccaacaat ttgaggtgcc
    12901 aatccaagca gctattggac aaaaaatcgt tgcccgttca gacatcaaag ccttgcgtaa
    12961 aaacgtcttg gctaaatgtt atggtggaga tgtttctcgt aaacgtaaac tcttagagaa
    13021 acaaaaagaa gggaagaagc ggatgaaaca aatcggctcc gtcgaagttc cgcaagaagc
    13081 cttcatggcc gttctgaaaa tggacgagga cgaaccgaag aaatagcaag ggtttgtttg
    13141 aaaacagtgt aaaaaataaa ccatgtttac atggatttgc caccggtttg ccaccggtgg
    13201 tttttttcgg tggcaaaaat caagaattct ttctaagatt ttccatgata tcgaccgttt
    13261 catttctcat cttatctgtt acatgcgagt aagtatccat cgtaattgaa attctgctgt
    13321 ggcccaatcg ttcagagatt tctttcattt ttgcgccatt ttcgagaaga agtgtagcat
    13381 gagtatgtct gagagaatgg aagttaaaag agagggagag tgcattcgat atcctcctag
    13441 tattccattt cactacactt ggcgtaacta gctcaccgtc ttccttcgta catactgcat
    13501 ttgaatcaat gtagagcttt ccatacttca ttcgattttc taattgttgt ttcttatgtt
    13561 ttttcagaat tgctagcaag gtttgtccaa taaaaatcgt tcgattggaa ctgcttgtct
    13621 ttggcgtacc atatacccat gcgccgtcat tctttaccat ttgtttctct acagtaattg
    13681 ttccatttgg aaaaatcgac atcatcccac gtcagaccac aaacttcgcc aacgcgcatt
    13741 cccgtataaa atccaatatt caaaggaata tagaaaggat gtccttcagg agtaatttct
    13801 agcatatgat caaagtcctc aagagaaatg atttttagat cttttttagt cgttggtcgt
    13861 gcttcatatt ttggtatttt tacatacagc ataggatttt gcttgattaa tccccaagga
    13921 taaaccgcca tattcagcgc attcttaagg acagagtgag taatagtcat tgttttcttc
    13981 gagtaaccct ttttaaattc agcattgatg aaattttgta aaagagcagg ggagagatcc
    14041 gtaagttttt tctttcctaa ataaccgttt atatgatttt tgatggtaaa tcggtagttt
    14101 tcataggtat tgtattttag atttagttta acgtattcct ccatccaaaa atcaaggtat
    14161 tgttttactc gagtatccgt acctaaaaag tattgtcctg tttcgtcaat atctgataaa
    14221 acttttcgta aagcagcttc ggcctctggt cgggtgtctc cgccaacttt ctccactttt
    14281 tttcttgagc catcatcatt gatatct
//
LOCUS       DAXQKX010000064        13938 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.066, whole genome shotgun sequence.
ACCESSION   DAXQKX010000064 DAXQKX010000000
VERSION     DAXQKX010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13938
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.066"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..914)
                     /locus_tag="ACF3MF_002230"
     CDS             complement(<1..914)
                     /locus_tag="ACF3MF_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent cysteine synthase family protein"
                     /protein_id="HFE3928177.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNHTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIY"
     gene            1342..1905
                     /gene="efp"
                     /locus_tag="ACF3MF_002231"
     CDS             1342..1905
                     /gene="efp"
                     /locus_tag="ACF3MF_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HFE3928178.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            2006..2176
                     /locus_tag="ACF3MF_002232"
     CDS             2006..2176
                     /locus_tag="ACF3MF_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928179.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            2391..3650
                     /gene="lysA"
                     /locus_tag="ACF3MF_002233"
     CDS             2391..3650
                     /gene="lysA"
                     /locus_tag="ACF3MF_002233"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HFE3928180.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            3637..4437
                     /gene="dapF"
                     /locus_tag="ACF3MF_002234"
     CDS             3637..4437
                     /gene="dapF"
                     /locus_tag="ACF3MF_002234"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HFE3928181.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            4440..5321
                     /gene="dapA"
                     /locus_tag="ACF3MF_002235"
     CDS             4440..5321
                     /gene="dapA"
                     /locus_tag="ACF3MF_002235"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HFE3928182.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            5318..6034
                     /gene="dapB"
                     /locus_tag="ACF3MF_002236"
     CDS             5318..6034
                     /gene="dapB"
                     /locus_tag="ACF3MF_002236"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HFE3928183.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            6040..6735
                     /gene="dapD"
                     /locus_tag="ACF3MF_002237"
     CDS             6040..6735
                     /gene="dapD"
                     /locus_tag="ACF3MF_002237"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HFE3928184.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            6751..7752
                     /locus_tag="ACF3MF_002238"
     CDS             6751..7752
                     /locus_tag="ACF3MF_002238"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HFE3928185.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            7749..9110
                     /locus_tag="ACF3MF_002239"
     CDS             7749..9110
                     /locus_tag="ACF3MF_002239"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HFE3928186.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            9070..10221
                     /locus_tag="ACF3MF_002240"
     CDS             9070..10221
                     /locus_tag="ACF3MF_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFE3928187.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            10196..11365
                     /locus_tag="ACF3MF_002241"
     CDS             10196..11365
                     /locus_tag="ACF3MF_002241"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFE3928188.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            11540..12919
                     /locus_tag="ACF3MF_002242"
     CDS             11540..12919
                     /locus_tag="ACF3MF_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFE3928189.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            13200..13938
                     /locus_tag="ACF3MF_002243"
                     /pseudo
     CDS             13200..13938
                     /locus_tag="ACF3MF_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEfa10 family transposase"
BASE COUNT         4661 a         2430 c         3021 g         3826 t
ORIGIN      
        1 aagtaaatgt tttttgataa atagcggtct gctgcgtctg gaaaaatcgt aacgacacga
       61 tgaccaggtg gtaaacgacg aatttctctt aatgctgctg caaaagccgc accactcgaa
      121 cttccaacta atagtccttg ttctcgtgct aactgcctag tatggttaaa cccttctaca
      181 tcagagattg tctcgatctg attgattgaa aggggagaaa gaaacggcgg aatgaattct
      241 acaccgatac cctcaatttc gtgaggggct ggatcaccac catttaacac agagccctct
      301 ggttctacac cgattattcg aatgtcggga tatttttctt tcaaaaaggt agaagttcca
      361 gcaaaggttc caccactccc aattcctgct acaaaactat ggatattttc tttgatttca
      421 tgaaagattt ctggccctaa cgtatgatag taagcagcag gattatcttt attttcaaat
      481 tgaagaggca gatagctgtt tgatatctcc tctgcaagtt ttttactttt gctgatggca
      541 ccgatgattc cttgctcact aggagaatgg atgatctttg ctcccaatgc tttcatcaat
      601 tgttgttttt ctaagctaaa cttctctgga acaacaaaaa ccgttcttaa tttgtatgtg
      661 agtgcggcca gagcgatccc aattcctgta tttccggcag ttggttcgat gatcgtcgtt
      721 ttttcattga tttttccttg ggcaaatcct tctttgatca aataactgcc caatctatct
      781 ttgatacttc ctccaggatt taaatattct agttttgcat aaatagcaga acctttaggc
      841 atagaatagt gctgattgtc aaagcgataa agcggtgtgg aaccaatagc ttctgtaatt
      901 gtcgagataa tcatatgggc ctcctaaaaa aagataataa aaaaaggagc tgactattaa
      961 atcagctcct tgaaagacat agagaaaaat tgagtagata aaaagataag ttacctggta
     1021 ctcattctat gaagggcaat taatagacat gacaaatagt atgctgcttt tatgcaccat
     1081 acaacagcaa cgattcaatt gtttttggtt gctgactgtc atgtgtatcc ctccaagtaa
     1141 aatttttatt aacgatagca tgaaaaaaaa taaaagtcaa aggcttgaaa gaaaaaaata
     1201 tttcgatagc atcgtttacc cgtgtttatt tttctgacaa ataggcatga gaccttaaaa
     1261 gatagagaat actctagttt tctggccggt tgtctgatac aataaagttg attatgataa
     1321 agaaaagaag gagcaaaaat aatgatctca gcaagtgatt taagagccgg tatgactttc
     1381 gtacaagacg gcaaactgat taaagttctg gatgcaagcc accataaacc tggtaaagga
     1441 aatacagtta tgcgtatgaa actgaaagat gtccgttcag gtgcaacata cgacacaacg
     1501 ttcagaccag aagaaaaatt tgaaaaagca catatcgaca caaaacctgt acaatatttg
     1561 tacacgatgg atgatacagc tttcttcatg gatttggaaa catatgagca atatgaaatt
     1621 cctgtagaaa cagtagaaga agaaatgaaa tatatcctag aaaacatgga agtaaaaatc
     1681 caattcttcg gtagcgaagt catcggcgtt caattaccaa caactgtcgt attacgtgtt
     1741 gtggaaacac aaccttccat caaaggtgca acagtcactg gttcaggtaa accagcgaca
     1801 atggaaactg gcttagtagt caatgttcct gacttcatcg aaacagatga attgttggaa
     1861 atcaatacag cagaaggttc ttatgtaaaa cgtgcgtcaa aataattcgc taacggattg
     1921 ataagaattt gaaaacagag cttgacctct tgaaaggcag atcatcggat ctgcctttca
     1981 agaggttttt tgtggaatca gcaaattgaa aaataaaaaa gtatttgatt ttatttatat
     2041 tttgaaagat gaatggcaaa agctagagaa agaaaaaact gcacttattt atgaagaaat
     2101 tgaaatgatt cataaaattg aaaatatccg aactattccg aactatattg aagcgaaaat
     2161 attttttcat cactaaatag tgttgaattt atgtttttat gtataaatag cttctaatag
     2221 ttcgggtatt ttgtttttat aaccattttt attcttattt ttaaaaaaat atttcgaaat
     2281 atactagaca attcagaaaa ttttgtttaa tattattcca ataaaattca aatctttatc
     2341 aaatgaaatt ccaataaaaa cggaaaaaaa gtgaaaagag gaatgaaaaa atgacagaat
     2401 tgataattgg cggagtcaca gcaagcacat tggcagaaaa gtataagaca cctctgtatg
     2461 tgtatgatga agaaaagatg agacaaacga tgctgtcatt caagcgaggc tttgtatcga
     2521 aacgttttga tacaaaagtg ctttacgcct ctaaagcatt ccaaacgatt gagatgctgc
     2581 atttagttcg tgaatatgga ttcgggctag atgttgtcag tggtggggaa atctataccg
     2641 ctttgcaagc tgattttcct agagatacta tctacttcca tggtaacaac aagacgccag
     2701 aggaactgat ctatgcactt gaaaatgatt tgttgcatat tgttgccgat aatttgatgg
     2761 aagttgaatt attagcagaa ttaagccaac gctatttaaa aaaaatctgt atcatgcttc
     2821 ggttgaatgt cggagtagaa gcacatactc atgaatatat cgtcactgcg catattgatt
     2881 caaaattcgg catgagctat gaaagtaaag agtgccaaca agcccttcag ttgataaaag
     2941 aaagcagcta tctagagtta gaaggatttc atgctcatat cgggtcacaa atttttgatg
     3001 ttactgcttg gttagctgaa atcgacaaat tgacgaatta cttaaccgat tttgaccaac
     3061 ctctttcctt gaatcttggc ggagggtttg ggattcgtta tacacaaaat gatcagccga
     3121 tcccagtcga agaggcacta aaaaaactga ttgaatatac ggaagaagct ttggaaaaac
     3181 gaaaactgac cattcgtcaa ttactgatcg aaccgggtag aagtattgtt ggagaagctg
     3241 gtacaacact atacacgatt ggtttcatca aaaagacacc acataaaaaa tattactttg
     3301 tagatggcgg gatgacagat aatatccgtc cagctctgta tcaggcagaa tacgattgtg
     3361 atttagcagc aaaactgtcg gaagaaaaaa cagagaaagt gacgattgca ggaaaaatgt
     3421 gtgaatcagg cgatgtggta attaaagaag cttatttgcc gaaagcagaa tcgggtgatc
     3481 ttttagctgt ttattccacg ggagcttatg gatactcgat gagcagcaac tacaatcgag
     3541 cgacacgacc agcagttgtt tttgtcaata atggccaatc aagactgatt gttcgcagac
     3601 aagcattttc tgatctacta aggggggaag tttcctatga tccttcataa atataatggc
     3661 tgcggaaatg attttatctt attagattac gcagaagaca cagattatag tcaattagcc
     3721 gcttctttat gcacaaaaga aaaatatgat atagacggat tgatcgccgt aaaaatcgat
     3781 ccgttggaaa tgatctatta caacaaagat ggcagccgcg cgccgatgtg cggaaatggc
     3841 attcgctgtt ttgctcgata cgtaaatgat cagaacatga tgaatgaaca ggaattcaac
     3901 gtagagacat tagcaggcac aagaaaaatt acggtgttgg atccctcacc tttttattgc
     3961 agcgtagata tgggagtgcc agatgattct ccggaaaaaa tcaaagctaa tcaaacttat
     4021 ccaataaaaa accaggaaat agagatcaat ggtgaaaaag taacgatcac tagtttattt
     4081 ttaggaacga ttcataccgt tgtttttgtt gaaaatgcgc gtgaggaagt ctggagaaaa
     4141 agaggtgaac tgatctgtca tcatcctttg ttcaaagaaa aaaccaatgt caactttgta
     4201 gaagtagtca atgaacaaga attgatcgtc cgtacctatg aaagaggagt aggttggaca
     4261 cttgcttgcg gtacaggttg ctgtgcctct tatgtggttg ctaaggaaac tgggaaaatt
     4321 tcagcagatc aggtagttgt tcacttggaa caaggagact tgatgatctc tggtgaggat
     4381 gcgatacaaa tggctggccc agcagttcat gaatggacaa gaatattgga ggaatgaaga
     4441 tgataaaagg ttcgatcgtg gcgctgatca cgccgatgaa tgaagaggga tcagtagatt
     4501 atgctggttt ggaaaaattg atccaattcc atttagatga acaaacagat ggattattag
     4561 ttttaggtac aacaggagaa tcttctacgc tcacacaatc tgaggaggag cagatccttc
     4621 aactgacagt aaagaaagtg gctggccgtg tgccggtgat tgcaggagct ggaacgaata
     4681 atacgaaaga aacgattgaa aaagcgaagc attttgcttc tttgggggca gacgcacttt
     4741 tggtcatcac cccttactac aacaaaacaa gtgatgcagg actagctgct cattttacag
     4801 caattgcaga agcctcaccg attccgctta ttttgtataa tgttccttct agaacaggca
     4861 tgtcgattcc aatccatgta ttagtaaatt tagcagaaca tcctaatatc attggtttga
     4921 aagaagcctc aggagatatg gcttatgtga tggatgccgc tcggttgatt ggagaagaat
     4981 tcttccttta cagtggaaat gatgatttga tcctaccagt aatgagtgta ggaggaagcg
     5041 gtgtaataag tgtatgggcg aatatccaac ctaaaatagt ccatgaatta gtaaaagata
     5101 cgcaggacgg aagatggcag caagcaaaag aaaagcaatt aaatgcactt gaactgatcc
     5161 atgccttgtt cagtgagacc aatcctattc ctgtcaaagc agccatgtca ttattagact
     5221 taccttccgg acctctacgc ctgcctttag tttctctttc aaaagagaaa aagaaacaat
     5281 tagctcagct tttgttaaaa gaaaggacgg ttgaaaaatg aaaatcggac tgattggcag
     5341 tggacagatg ggaaatagag tcgaagaagt tgcacaagaa agaggagata cggtccttct
     5401 tttacggacg gcacctaaag aagcaactac gcttgctttt acggaactgc cagaactgct
     5461 tattgatttt tctcatccag ataatttaga gaaaatcctt tcgtatagct tatcatatca
     5521 acttccgtta gtcattggca cgacaggtta tacacaatca cagttccaag aaataaaaga
     5581 acatgccaaa catgtacctg tgatgtatag tgctaatttt tcgttcggca tcatggtgat
     5641 gaatcaacta atcaagcaag cagctgcaat gttgcaaggc tggcagatcg aactgattga
     5701 aaaacatcat agtcgtaaaa aagatgcacc atctggtact gcaaatatgc tgcttcaaac
     5761 aatccaagaa gtgcaaaagc tgcagcccgt atacaactgg caagggaaaa aaagagaaga
     5821 aaaccaaatt ggtgtacaca gtattcgtgc aggttcttta cctggtgaac atgatgtatt
     5881 gtttgctgct actgatgaaa tatttacgat caaacatgaa tctttttcta atcgaatctt
     5941 tgctgcaggc gcagtagaag cagcggactg gttgaaagat cagtcaccag gttattacaa
     6001 attagaagat ttattaatgg acaaaggggt gtaaaaaacg tggaagctca agaaatcatc
     6061 cgctacattc aaacggcatc taaaaagacg cctgtgaaag tctatctgaa tgtaaccgag
     6121 ccaatcgaat ttaaagaaag taaagttttt ggtgaaggaa gcagcttcgt tgtttttggt
     6181 gactatgaga cgattgctcc ggttttagaa gctgaatcag aaaaaatcat tgaaatcgaa
     6241 atcgaaactg ctgcaagata cagcgcagtt cctttgctag atattaaaaa aattaatgct
     6301 cgtatcgaac caggtgctat tatcagagat caagtgtcaa tcggcaacaa tgccgtgatc
     6361 atgatgggag cgattatcaa tattggtgca gtaatcggtg aaaacacgat gattgatatg
     6421 ggtgctgtct taggtggacg agcgacagtg ggcaaaaact gccatattgg tgcaggagct
     6481 gtcttagcag gtgtgatcga accagcatcg gccaaaccgg ttatcgtaga agacggcgta
     6541 ctggtaggtg cgaatgcagt gattgttgaa ggtgtccata tcggaaaaga tgcagtcgtg
     6601 gcagcaggag cagtggtttt agaagatgtg gcagcagaaa ctgttgtcgg tggaatacct
     6661 gcacgtgtat taaaaataag tgatgatcag acaaaagaaa atacagcatt gattgctgcg
     6721 ttacgcgaat tatagaggag atggagaaaa atgcgcgaaa tagatacctg tattgtgggg
     6781 gcaaccggat tagtcggcca aacgatgctc aaagtgttag aagaatatga ttttccagta
     6841 ggacgattga aattattagc ttcaaaacgt tcagccggta aagtttgtgt attcaagaaa
     6901 aagaaacaca ctgtacagga attgacagaa acttcatttg aaggatatga tttagcgcta
     6961 ttttctgcag gtgcttctgt atccaaagag tttgcgccaa tcgcacgaag tcagggacta
     7021 tttgtcatag ataattcctc agcatggcgg gaagattcgg atattccatt aatcgttcca
     7081 gaggtcaatc tggaagacta tacattgaat cggctgattg caaatccaaa ttgttcaacc
     7141 attcaagcgg tacttccgct taaagcttta caagaagcct ttggtatcca gcgagtcaat
     7201 tattcgacct atcaagcagt ttctggttcc gggcaaaaag gcattgaaga tcttcatcgt
     7261 acgcaaaatg acgaggaacc agttttgtat ccttataata ttagccaaac ggtgattccg
     7321 gaaatcgatc agcctttgga aaatgggtat acaaaagaag aacagaaaat gataaatgag
     7381 acccgtaaga ttctgcatca gcctgctttg ccagtatcag caacctgcgt acgtgtgcca
     7441 atcgaaaatg gacatggagt ctctgtggca gttcaactgc aaaaagagtt tacgacggaa
     7501 gaaattagag agtgtctcag ccagtttcca gggattcaat tagaagatga tctagcagca
     7561 cataaatatc cgacgagcat tcttgctaga ggaacagata tggtttatgt tgggaggatc
     7621 agaaaagaca cttctttaga gaacggattg ttgttctata cgactgccga taacatacgc
     7681 aaaggagccg ctgcgaatgc cgtacagatt gctgcagctt taatgcagaa aatagcggag
     7741 gtggcaagat gagtaatacg ctgaaagtag cgaaattcgg cggaacatcg atgtctcatg
     7801 aagagcaatt caaaaaagtc cgtacaattg ttctttcaga tcccaatcgc caagtgatcg
     7861 ttgtttctgc tttaggcaaa cgtacgtcag atgatgacaa agtaacagac ttactttatt
     7921 tgatttatgc ttaccttcag catcatgttg attggacacc cctttggaaa aggatttgtg
     7981 atcgtttcat tcaagtaaga gatgttcttg ccctgcagtt acctattgaa gatgaactag
     8041 cacgcataca gaaacaactg gaagacgaaa agataactga agattattta gtaagtagag
     8101 gtgaatatct gactgctcaa ctgatggctg agtatcttgg ttaccagttt attgacgcaa
     8161 aagacctgat tttctttgac tatgatggga aaatcgatca ggaaaaaaca gcacaggaaa
     8221 tcacaaaagc atttaaaaga tatccgaaaa tggttgttcc agggttttac ggggcgaacc
     8281 ctgcaggaaa agaaaaatta ttgggccgtg ggggaagcga cattaccggc gcgatactgg
     8341 cgaagatgtt gcaagcggaa agttatgaga attggacgga tgtttcagga atcatgatgg
     8401 ctgatccgcg aatcatcgat catcctaaaa tcatcgagga aatctctttt agagaactga
     8461 gagagatggc ttatatgggg gctaacgttc ttcatgaagc agctgttttc ccagttcaag
     8521 aggctgatat ccccatccaa ataaaaaata ccaatgatcc tttcgctcaa gggacaaaaa
     8581 tatcaaatca cgaaatagaa aaggaaaatg gactgacagg aatagctgga cgcaaggatt
     8641 ttctttccat cactttattc aaacgtcata tgtccgatga aatcgggttt atctggaaag
     8701 caatgagcat ttttgctaaa catgagatat caatcgaaca tattccttca gggatcgaca
     8761 atatcggagt gatcgtctca gcagaagcga ttgccgataa gttatttctc atcacgaaag
     8821 aattaaaaga aacacttggc gtggaagaaa tcgtcgtgat cgaagactta gctttgatct
     8881 ctgtcgttgg gggtccgcat aaagaattga ttggattatc tgggaaagtg ttatcgatat
     8941 tgaacaaatt agaaattcgc acatcgatct tatcacaagg agcacaggag ttgaatctga
     9001 tcatcggtgt accgaataat caatatgaaa cagtagtgaa gggtatctat gaagggatgg
     9061 tgaatacgga tgctgaaaga atatcgaatg gcactccatc aaattcctga aatcgggttt
     9121 catgaattca agacaaaaaa atatttatat gaacaagtaa aaaacagcga ggccgttatc
     9181 catgaaatcg gcgaaacagg actactcctt tattttgata atcagcaaga agaaacgatt
     9241 gcttttcgaa cagatatcga tgcactgcca gtcaaagaag aaacgaatct ctcttttgct
     9301 tctaagcatg aaggttatat gcatgcatgt ggtcatgacg gacatatggc gatgctttta
     9361 gggttgactg actttataac taaacacatt gaggatctta tttataatgt agtactgatc
     9421 tatcagccat cagaagaaat ttccggtggc gcacaaagcg ttattcagtc aggattgttg
     9481 gataaatatg aagtacaagc aatatttggc tttcatctat ggcctggact agctaaggga
     9541 gaagttttct ctcgaccagg acctttgatg gcacaaagca gtgaaacaga cattatcatt
     9601 aaaggccagt ctgcacatat tgcttctagt gaaaaaggaa tcgatagtct ggaggcagct
     9661 gtacgatttt tgaagaatgt ttatgatttt gaccggcaat taccggcaga gtggaatcat
     9721 ctaatgaaat ttggccaaat ccaaggtgga acgatccgaa atgttttagc tggagaagtt
     9781 attgtatccg gaagtatccg ttcttacagt tcagatatgc aaaattattt gaagagggga
     9841 ttagaccatt tagcagaaca gtttcactct acagctacta tttcttttcg ctataatgac
     9901 ggctatccag ctgtaatcaa ccatagaggc ttatatgcag cactgttaga ttcaaacaaa
     9961 ctacatgaat tagatgctcc agttcttcaa gccgaagatt ttggcatata tacgcaacaa
    10021 tatccatgtg tatttttctt tttaggtgtc ggtgataccc ctgctttaca tgatccgacg
    10081 ttcgattttg atatggatgt tttagaaaat ggtgtagaat ggtacaaaac gattcttttt
    10141 acagaaaatc ttcttgtaaa aatcgatagc agttcaaaag aggagcgagt aaataatgat
    10201 gaatttatcc aatcgattta gtcctaggct ttctagaata gaagtatcaa aaatacgaca
    10261 attcgatcag caaatatcgt cgataccaga tgtgatcaaa ctcaccctgg gagaaccgga
    10321 ttttccaact cctgaacatg tcaagcaagc aggaatagca gcgattgaag aagacttttc
    10381 tcactatacc ggaatgagag gattagagga actgcgggaa gcggcttgta tatttcagca
    10441 acagcgttat ggattaactt atgatccgca aacggaagtt ttgacgacag ttggtgcaac
    10501 ggaagcgatt gcctctgcgt tgttatctgt tttggaagaa ggagacaagg ttcttattcc
    10561 agcgcctgct tattcaggat atcagccatt agtggaacta gctggtgctg aattgatccc
    10621 gatagatact tctgacacag ggtttgtctg tcagccggaa caatttgaac gagcatttga
    10681 acaatatgga tcagctgtca aagcagtcat tttaaactat cctaacaatc ctactgggac
    10741 gacattgtct gcaaaacaat tgaaagcaat cgctgaggtt ttaaaaaaat atccggtatt
    10801 tgttataagt gatgaagtat atgctgaatt gacttatagt ggaacgcata tgtccatagc
    10861 tacttatctt ccagaacaaa caatcgtgat aagcgggtta tccaagtcac atgcgatgac
    10921 tggttggcga gtgggcttta tttttgctca aaaagccctt attgacgaac taattaaagt
    10981 ccatcaatat ctggtgactg ccgctacaac gatgtcgcaa aaagctgcgg ctgaagcgct
    11041 aataaatggg gtgaaagata gcgagaatat gaaagagcaa tatcaaacac gaagagacta
    11101 tctggtccag caattggcgc ctttaggatt tgaagtgacc cagccaaacg gtgcatttta
    11161 cttgttttgc aaactcccag ctgccattca aactgactct tggcagtttt gtgtagaatt
    11221 agcggaacag gcaaaagttg cgtgtatccc aggaattgca tttggcccag aaggagaagg
    11281 ttatatccgg atttcttatg ctagcagcat ggaaaaatta catgaggcct gcaaacggat
    11341 caaagacttt ttaacagaac agtgattcat agattttatc aaaaaaacaa tcgttaattt
    11401 tgcggtatat tctgcaagga gacgattgtt ttttaaattt agttcaaatg aacgcgtttc
    11461 ttttgattca taactaatgt aatgttaagt ttaaattgtt tagaatgatt ttaaaagaat
    11521 attcaaggag gtttcatcaa tggaaaaaat caaagttgtc attgtaggtg catctcatgg
    11581 agggcatcaa tcgatcttgg aactattgac acgatacggt gaaaatgtag atatcacgct
    11641 atttgaagca ggagactata tttccttcat gtcatgtggt atggagctgt atttagaaga
    11701 caaggtaaca gatgtaaatg atgtacgtaa tttcagacca gaaaactttc cgcaatccaa
    11761 tgttcatatt ttaaataatc acgaagtaaa aacgatcgat gccgataaaa aaacagtaac
    11821 ggttactagc gcatcagata acgaaacaaa agaatatcct tatgacaaat tgattttgag
    11881 ttctggtgtc aaaccaaaca atctgccagt accaggagca gatctagaaa atgtctactt
    11941 gatgcgtgga tacaattggg caaccaaaat caaagaaaaa ttaaatgatc cggctattaa
    12001 aaaaatcgct gtcgtaggtg cgggttacat tgggatcgaa gcagcagaag caagccgaaa
    12061 agctgggaaa gaagtcgtat tgcttgatgt gatcgataga cctttaggca cttatttaga
    12121 tgctgagatg acagatattt tagaacaaca cctaaatgaa aacggtattg aagttttgac
    12181 aaatgcaaaa atcgaagctt ttactggtaa cggaaaagtt gaggcaatca aaacaagtga
    12241 aaaagaaatc ccagcagatc tagtcattca agctgccggt gtgaaggcaa atacagaatg
    12301 gttaaaaggg atcgtcgact tagatgaacg tggctggatc caaacaaatg aatacttgca
    12361 aacgaatctt ccagatgtgt atgcagtagg agatgctaca cttgcttatt ctatcccagc
    12421 acgcaaaaaa atgccgatcg ctttagcgac tgttgcacgt agagaagcac gttatgtagt
    12481 aaaacatctt tttgaagaag taccaaacaa accgttcggc ggagtcgtag gttcctctgc
    12541 attaagtgtc tttgactatc attttgcagc aagcggattg aatagcttta cagcagcaaa
    12601 agcaggagta gatgtacgag tgtcttatta tgaagatacg ttacgaccaa aatatgtacc
    12661 agaagaacaa ggaaatccaa aagtgtccat ccaattattc tcggatccaa tgacccatca
    12721 attgctagga ggagcagtat tatctaccta tgatgttaca ggtcaaggaa atgtattggc
    12781 actagcgatc caaaacaaac tgactttaga agaactagca gaagctgact tcttcttcca
    12841 gccaggcttt gaccgacaat ggagcatgtt gaatctagcc gctcaacaag cgttaggaga
    12901 agaaccattt gtagaataag aaaacgaaat atttgaaaag aggttgtgaa aaagctgcct
    12961 tgcatcaagt aataagaaca gccaagtaaa aacagcttct tatgttttta acttggctgg
    13021 acttattacc gcagatgcaa gcttttgaac accgtttatt ttcaaaaaag ggactgtgac
    13081 acgatttgtg taccgacccc caaaagttag accaaaaaat ctaacttttg gaggtcggta
    13141 ttttttatgg ttaaatatac ttttgaactt aaattaaaga tcgttcatga ttatttggat
    13201 ggcaaaggcg attggaccgt aaaaatccag atcaagagat tgaagcggaa atgcttaaaa
    13261 ttcgggagaa gcacaaggat tatggctgtt tacggatgac caatgaacta agaaaccgcg
    13321 gtttctctat caataaaaag aaagttcagc gcttgatcaa gaagctagga ataaaagtaa
    13381 cggcatacac gcgtaaatca cgtcgctaca attcttatcg aggaaaagtt ggagcagtag
    13441 ccaaaaatcg gatccatcgt cgtttctaca ccagtatctg ccatcagaaa atcacgacgg
    13501 atacaactga atttaaatac catgaagtgg atgccaaagg cattatccgt caaaagaaat
    13561 tgtatctaga tccttttatg gatatgttca atagtgagat tttatcctat cgtatctctg
    13621 aaaagcccaa tgcattagcg gtaatggaag gtttggagga agctatccag accactaacg
    13681 attgtcccta tcgtcgtacg tttcactcag atcaaggttg ggcgtatcaa atgaaagctt
    13741 atagaaacaa attgaaggag tacaaaatct ttcaaagcat gtctcggaaa gggaactgct
    13801 tagataattc acttatggag aatttttttg gcttattaaa acaagagatt tttcacggga
    13861 aagtttataa ctgtttcgag gaattaaaat cagccatcga tagctatatc tattactaca
    13921 ataatgaacg gataaaac
//
LOCUS       DAXQKX010000065        13870 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.067, whole genome shotgun sequence.
ACCESSION   DAXQKX010000065 DAXQKX010000000
VERSION     DAXQKX010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13870
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.067"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(180..1547)
                     /gene="nhaC"
                     /locus_tag="ACF3MF_002244"
     CDS             complement(180..1547)
                     /gene="nhaC"
                     /locus_tag="ACF3MF_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFE3928190.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(1648..3078)
                     /gene="tyrP"
                     /locus_tag="ACF3MF_002245"
     CDS             complement(1648..3078)
                     /gene="tyrP"
                     /locus_tag="ACF3MF_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070908 - tyrosine:tyramine antiporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-tyramine antiporter"
                     /protein_id="HFE3928191.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKKFRRKIKK"
     gene            complement(3321..5198)
                     /gene="tdc"
                     /locus_tag="ACF3MF_002246"
     CDS             complement(3321..5198)
                     /gene="tdc"
                     /locus_tag="ACF3MF_002246"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HFE3928192.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(5489..6745)
                     /gene="tyrS"
                     /locus_tag="ACF3MF_002247"
     CDS             complement(5489..6745)
                     /gene="tyrS"
                     /locus_tag="ACF3MF_002247"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HFE3928193.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(6857..7062)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            7325..8626
                     /locus_tag="ACF3MF_002248"
     CDS             7325..8626
                     /locus_tag="ACF3MF_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFE3928194.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(8695..9294)
                     /locus_tag="ACF3MF_002249"
     CDS             complement(8695..9294)
                     /locus_tag="ACF3MF_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFE3928195.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            9548..10429
                     /locus_tag="ACF3MF_002250"
     CDS             9548..10429
                     /locus_tag="ACF3MF_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFE3928196.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            10442..12052
                     /locus_tag="ACF3MF_002251"
     CDS             10442..12052
                     /locus_tag="ACF3MF_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFE3928197.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(12129..12788)
                     /locus_tag="ACF3MF_002252"
     CDS             complement(12129..12788)
                     /locus_tag="ACF3MF_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFE3928198.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(13071..13736)
                     /locus_tag="ACF3MF_002253"
     CDS             complement(13071..13736)
                     /locus_tag="ACF3MF_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HFE3928199.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
BASE COUNT         4061 a         2808 c         2547 g         4454 t
ORIGIN      
        1 gtgggacaaa agtaaagaac acttttgtct cacgctctaa acacgtataa acggcggaag
       61 cagaagcaac tccttcggaa ataagctgaa attcacaaaa atttaaaaag caattttctt
      121 gagtttcttc ttatttcttg gagttaaacg cttctgtccc agcctctttt ttccttcctt
      181 caatttttta cacgtcgacg attcaataaa aaaccgccta atattgtaaa gacaggtgca
      241 agaatcgaga aaaaggcgaa tggcaagtaa tgcaacgcgc taactttcat cgttcccata
      301 atgaatgtgc cgctgactcc ccacggtacg agagaattga cggtcgcacc tgaatccgct
      361 agtgttcgtg tcaaataggt ttttgataag ccaacgtcat caaaagaacg cttgaatgtt
      421 tctcctggaa gaatgatgga cagatactgt tctccaacga tcagattgat tccgatacag
      481 ctcaaggcag taaacccgac taaacgagaa ggtcggtcca tcttttcttt taattcttga
      541 acgatggtat caacgatcag atatttgatc agtaacccac ctaatgccaa tgcaagtaaa
      601 atcaaactag cagaacctaa catactcatg atcccgcctc gagaaagcag ttcatctagc
      661 tttggatcag gtgtatttgc gacataacca ttcatcaaga tgtctgctgc ttttccgacc
      721 gtcaaacttt tctcatggat aaaagaaaga acgagagcag ctgtcgatcc cgctagtaat
      781 gtagggatag ccggaatttt tttgattgcc cccccaaata aaataactag tggaatcaat
      841 gtccaaggag agatccaaaa gctcgctttc atgttttgga tcatttcatt gatactagct
      901 agatcggctg aatgactgtt atgtcctaat atcgtataaa aaatcaacga aaggacgaat
      961 gctgggaaat ccgtataacg cataccagcg atatgttcga atagattaac tcctccaata
     1021 cccgctgcca agttggtcgt atctgataaa ggcgagcagt tattccctaa aaaggcaccg
     1081 gaaacgactg cgcctgtagt cattgcatca ttgaatccaa gtaaatgacc gatccccaaa
     1141 aaagcaattc caatcgtcga aatcgttgta aatgaactgc cgacagtcac tccgacaatt
     1201 gcacaaacaa gaaatgctgt cggtaaaaag aaacgcacag aaacaagttt aaatccataa
     1261 accataatcg tagggatggt tccagataaa atccatgaag caactaagac accaatcaaa
     1321 agaaaaatca ggattggaat gatccctgga gtgattcctt tgatgatccc gtcatggatc
     1381 tcatcccatg tgaacttttt aaatctgcca taaaacaaca aacacatgaa agctgcaagg
     1441 atcgggatat gtggcgagag ctggaatccg atgatcagta ctcctaggag tgccaacaac
     1501 acgatcaata cagcgatact ttcttttaaa gaaatatttt tattcatcgt cgatctccta
     1561 tttcaaatga aaaggccctg ccatgaaaaa actattcact tggcaggacc tcctactaaa
     1621 tcagcgacaa aacgtcggct gaaagactta tttttttatt tttcttctaa actttttttc
     1681 tacctcaatc ccccaagaat ctttcttgaa gtgattgatg atcaatggaa taacgaacat
     1741 gaccactgtg atagctgcta ctaataatgc atcactcaat gtcgctgtac ctaatgtagc
     1801 aaatacgaca acgatgatag agaagatcag catgcagctg actacccaag ctaatccgtt
     1861 tccgttttta ccaattcggt aaggacgttc gaattctgga tgtttcttac gcattttaag
     1921 caatgaaaca gcaatcaaaa tgtacacgat acaataaata acagttgtag catttgtaag
     1981 tgtcaagaat acagcactta cgtcatccat tacaccataa agcaaagcaa ataatgaaat
     2041 aacgattgat tgtgttagaa cgacatttct agatacgccg tatttgtttt ctttatggaa
     2101 tccgaatttt ggtggaagga atccttcacg agctacttgg atgattgttt ttgatggtcc
     2161 agtaacccaa gctgataatt gtaaaagcac accaataaat accatgaagc tgaagatatt
     2221 tccgatcact tctggtaagc ctaggatttg acagtcaatc aagataggct gcgtgatatt
     2281 tgctaattcc atttttccat ctggtacgac atttgctaca agcatcgcat tgatgacatt
     2341 caataaaact aatccgatca aagcgataaa tacgcctttt gtataatttt ttgttgcgtc
     2401 tttcaaacga ggcatgtaaa cagaactcat ttcgatccca acaaaaataa atgtgatacc
     2461 agctaagtat ttcaatgaat caatatgttc caagtcaggg aaagcttttg accatgaaaa
     2521 gtcacctaga tagccgtttg agactagtcc gactttgaag gctgccaaaa cacctaaaac
     2581 gaacatgatg actactggga tatatacccc tagccataca ccgatgttcc cgccgacttt
     2641 tgccatatcg aatttcaagt tcaagatcgt gatgatccag tagataacta aaatacaacc
     2701 taaaacgaac cagtgattat tgccaagttc tacattacca aatgtgtttc ctaacaatgg
     2761 tcctaaagta gaagcgacca ttaccatacc tgggaacatt tgcacccata atagccatgc
     2821 aacgacaaat ccccatttgc tgcccagtgc tgtttttacc cataactgag gaccgccttc
     2881 ttgaggaagc atcgtggaaa gctcaccgga aaccattgat atcggaccgg caaaaaacaa
     2941 aactgcaaaa attgaataaa aaatcaatgt ccaaccgact gcggctaacg taggaatact
     3001 ccgaaccgtt gcacacagtg ccattgtcag accgataaag gtcccaagac ccattttact
     3061 tacttcagat ttactcaccg ttgacactct ccttgatttt ttggataaaa taacggtgtc
     3121 tttgaagtag tttcagcaat aaacgaaaca attcagcgaa tatttgaggg gattctttga
     3181 gtttattgct tgaagggttt cttcaaagac aacctcaaaa caaagggatc gaagagctta
     3241 ggtctcccct tgctcttcag atccaaacat gcgtcagaaa cagttagtat tcaagctgtt
     3301 ttctaacatg attaccttgc ttattttgct tcgcttgcca ataattggtc tgcgtagatt
     3361 ttttccaatt tttcttgaag agctgctttg attttttcag catattcttc aaagtgttct
     3421 tctttgttca tgtatggtgt cattacgctg gcacgcaata cagttacttt tccggcacgg
     3481 ttccattctt catctgagaa tcctagttgg ttcacaaatt gtaatgggct gttgccatag
     3541 tctgggatag caaagtcagt atgtgaagtt aagaactcat taccgtaaat gcttcctttc
     3601 acgtatgaag aataatcata tacgtcatgg ttcaatttat tcattgcaac taagtcatcg
     3661 ttgccttttt ctttgaatac atagtctacc atattgaaat ctggataagt taatggatga
     3721 acttcgattt ctttgtctcc tactttaaat gacaagtcat tcaagaagtt gtagaaacga
     3781 tgtgcacctt cgattgatgc acccattaat ttaccatatc ctgtgacatt caaaggtaag
     3841 acatggtgtg ctgcccaaac gctggctgct gttgcccctg cttttgaacc ttccaagata
     3901 taagccccaa gtaatgctgg gatatctgcg cctttttcaa atacatatgt cgcaaagtaa
     3961 gagataacgt ctctcatgcg gatatctttg atgacgatac caccggcaga atatggaaca
     4021 tagcccattt tatgtgggtc aatcgttaca gattctgctt cttcgattgc tttatacgca
     4081 ctgtgtactt cttctaagat ataatctttg ttttctgtaa agacattgta tttgtaatga
     4141 acatctttta aatcttcaaa tggaatgaag ttgttgtctt cgtctaagaa aatcgcacgg
     4201 ccgtatccgc cataagcagc atctacgtgt aagtagaagt aaataccgtc tttttctaat
     4261 acgcgacgca atgcaacgat tttatcgata ccgtcgattg ctccttcttc tgttgatcct
     4321 acaacaccga ctacacctag gattggtgtt ttttcagctg ctagaccacg aacgattttt
     4381 tcaagttcgt tgatgtccat gcgatagttg tggtcaactg gcactggaat cacttggtct
     4441 aaaccgatac cgatgatgtc ggcagctttt agccatgaat agtgtttagt ttgtggaacc
     4501 aaccattttc ctaatttttc taaatgtttt ccgctacgtg ctgagtgagc tttgatttcg
     4561 tcgatttttt ctgggacgct gtctaacaga ttcatgattt cttctgttga caagttcatt
     4621 aattcccaat cgctttttcc agcaactagt tcaggtgtca cttctttcat tgcaagcggc
     4681 aatgatttga tgttgcgggc ataccaaagt ccttctaagt ttgctaaaga accatcagca
     4741 acgatgtggc cccagccatc tttatagctc attaattttg caaattccat tcctacttct
     4801 tcttccattt ggcttgttgc aggagaagat tcataggcaa cgttattacc attccatagc
     4861 atagcaaaat tgtacgctag taaagatggc atcaatgttt cagagttcat atgaccccag
     4921 taacgtccgg cattatgcca aggaacggaa tgggtacgca tccgcgctga aatttctgat
     4981 agaacatcct ttgttttatt cacagtgtgt tcaaaactag cactgctttt ttcttctggc
     5041 gtaataatag gcatgtcttg aggcatgtag ttttgacgcc agcctaaatg ttcatccacc
     5101 aattcattca acaaagcttt atagatttgg ccgttctcag ctttgtcccc aatgaatagg
     5161 gcatttaggt ttagatcttt cgacaatgat tcactcatag tgaaaccctc ctaaaaaaat
     5221 atttaaattt tgtcgagccc tacattacac ctgttcttct attctgtaaa ctaagttttg
     5281 gcctgatttt taatcatatt ttaatatgta tcaattatcc gaattgttca cacttttgaa
     5341 ataattaaaa aaaacgaggg aatttacaaa tgtaaactcc ctcgcaaaga ttgtattaac
     5401 gacaaccagc gttctatttt aggatgggtt tcaaaattgg aatgttgtaa tagtatttcc
     5461 ctttttcaag gtaaaaactt actaaattct aatcaattac tttggccaaa aagtaatttt
     5521 tcttaccttt tcgaataacc acaaacttac catcgaattc atcggatgga tttatgacaa
     5581 aatttaaatc ggtaacgcgg tcaccgttaa tacttatagc tccgtttgaa acatcttcac
     5641 gtgcttgacg tttagatggt tcaatttttg tggaaacaag cagttccacg atattttcag
     5701 gtgtgcttga aatttcaacg ttcggcattt taccgaatcc ttgcgcgatt tcttccgcat
     5761 ttagttcttt aatatttcca gagaacaatg cttgcgttat tttttgcgct tctttcaagt
     5821 cttcttcact atgcacaaat cttgtaactt cttctgccaa acggcgttgt gcttcacgtt
     5881 tctcaggttc tgtctctact tttttcgcta agtcttcgat ttcttcttga gacaagaaag
     5941 taaagaattt caagtatttc actacatcgc gatcatcttg attcaaccag aattggtaga
     6001 actcaaatgg tgaagttttc ttcggatcaa gccaaacggc accgcctgca gtttttccga
     6061 atttcgttcc gtcagccttc agcatcaatg ggatcgttaa accgaacgct tctgcttctg
     6121 gtccttctaa ttttcggatt aggtctaatc cagctgtgat atttccccat tggtctgctc
     6181 caccgatttg caattgcaca tcgtatgttt tatgcagatg caaaaagtcg atagattgca
     6241 ggatttggta agtaaactct gtaaatgaga ttcctacttc caaacggctg gcaacgatat
     6301 cttttgctaa catcgtgttg atgttgaagt ttttaccgta gtctctcaaa aattcaagta
     6361 aagagatttt tgacaaccag tcgtagttgt tcacaaatgt gatatttgca tctttaccaa
     6421 acaattttct catttgattg gaaagtgcgt ccacgttatg ttgcacttgt tccatcgttt
     6481 gcaacacacg ttctgttttg cggccgcttg ggtcgccgat cgttcctgtt ccgccgccaa
     6541 tcagaatata tggatgatgg cctgccaatt ggaatctttt catcatcata aatggaatca
     6601 aatgtccgat atgcatcgaa tcaccagttg gatcaacgcc gcaataaagt gaaatgctct
     6661 tttcttcaac gagctcgcga agtctttctt cgtttgtttg ctgattaatg gcgtcgcgcc
     6721 aagttaattc atcaataata ttcattttac tgacctccgt gtagtttttt tatgaaagca
     6781 ggaacctgct agcatgtgta attaattatt tcttcaggat aggataggaa ataaaaaaag
     6841 tcccttggca tataagccaa gggacgaaat ctcgcggtac cacccaattt gtatgtctag
     6901 atatccaaca tacctctcga acatttaacg ctgtcgcgtg gcaatcactg ccaaagactc
     6961 ctgaaatgta attcgcttta aagcatgtac tggtttgcag cgaccaccag ctttctgaaa
     7021 cattggcttt aacaactact tcgtttcgat cttcgtcttg ttattattaa tatgtgtcta
     7081 tcatagagcg caactttttc tttgtcaaca gaaaaaggat atttttttta aattcctcat
     7141 tttttctttt ttgaatccgc tctaattccg aacattttat tttcaattat tgttaaaaga
     7201 aataactttt tctgtatttt ttctgcaatt tatcgagaag tcactttact ttgcctctta
     7261 ttctttcttc gttacaataa ggaatgggac aagtaaaaaa atgaaaaagc aagggacgag
     7321 gtatatggaa aaaaagcaaa aaattatttt aggagccact tctgctttaa ctatcgttat
     7381 tttaattcta agtttgtttt ttgtcatccg atcatctaca aaaaaagaac caatcattcc
     7441 tgaaaaaaaa ataacagaaa aagcaaaaga accgacagat gataagcaac aactagttac
     7501 tcaagcaaaa aatctggctc aaagctacga ttatgaccaa gcgattgcgt tattggaaaa
     7561 agatagtaag aacggatcta ctgaaacaca acagcttctt caaacactaa aaaaggagaa
     7621 agaacaactg atcgactggt ctgatcctac tcagatctct catgtctttt tccacagctt
     7681 gatcgtggac ccgcaaaaag ccttccactc tcaacaggca caaggataca aagattatat
     7741 ggtgactgtt gaagaattca accgttcgat cgaacaactt tatcaaaatg attttgtttt
     7801 agttaatttg aatgatttga tccaaaaaga cgaacaagga aatctttcct ttaacgggct
     7861 tgcgctacct gaaggaaaaa aaccattggt tctttcacaa gatgatgtca gctattatga
     7921 atatatggat aattccggtt ttcctagccg attggtcgta tcaaataaca atgaaatcaa
     7981 aaatgtctat aaagagaaag ataaagaaga aatcggtgac tttgacatgg ttcctctgat
     8041 cgatgccttt gtcaagaaac atcctgattt ttcttatcga ggcgcaaaag gtaccttggc
     8101 cctgacaggt tacaacggag ttttaggtta tcgaacatca aaatctcaat atggagacaa
     8161 tgaaaaaaca aaaaaagaga ttaaagaagc taaaaaagtg gcggaacagt tgaagaaaga
     8221 cggctggagc tttgcttccc atacatgggg tcacttgaat atgactcaag cttcactaga
     8281 agatgtaaaa aaagacaatg aattgtggca gcaagaagtt gcacctatcc taggaaaaac
     8341 aaatattctg atttatccat ttggtgcaga catcagcgac tggcagcctt attcagcaga
     8401 aaatcaaaaa tttgcttact tgaagagtca aggtttcgat attttctgta atgtcgatgc
     8461 ttctacacca gcttggggac aattaggtac ggatttctat cgaaatgctc ggatcaatat
     8521 cgatggcatt cgttttcaat ctgatttaga cggaaaaaat cctattcttg atccattcat
     8581 caatgtccat gatgtctatg acaaagaagc acgcgaatct gcttgatttt acgtcattta
     8641 tgaaccaaaa aagccgaact gacattttat cgtcagtttc ggctttttta tgctttattt
     8701 cttcttcggt gcgattccct tgatcaggac ttctgtccat tctgctgtat atggaagcag
     8761 ttttgcgtat atctccggct tagaaattcc ttctaccatt gcttgaaaat agaggatcaa
     8821 gaactcatcc gaatatttca aatccacttt tccttctttc cgccctcgat ggaaaagatc
     8881 aagcatgata ctgaaacttt cttgcgtata cgcatccatc gcgtcagaaa attctttttt
     8941 ttcttttttt gtatagtatg tcatcaaatc gatataaaat tgtttgttca ctcgattgag
     9001 ataacggatt ttgttttcac tcatggcaat cagtgtttct tcaaatggaa gattttccgc
     9061 aatcaacgct ttcgcttctt gccctaaatc attcataaat gcaaaaaata cttcataaat
     9121 cagcccttcc ttgctgccaa aatatttaaa aatcgtcgct ttacttacct gagcgttctc
     9181 agctacctta tccattgtca ctccagcggt tcctatgtct gtgttcatca agtcaaaagc
     9241 tgcttgtaaa atctctttct ttttctcttg tgctctcttt tcaaaaccgt tcatttgtag
     9301 agcctcccgt aattttaaac ttttataata tatatagttc aaatttattc tgaggtttat
     9361 tataactatc tattgagaaa gtatcaagct agcaattcct tgtttatgaa ttcattgaca
     9421 gaaatttata aaaagaatat tatgtactaa aataataaaa aaagttttat aaaaaggtat
     9481 aaaacctttt tattaaacta tttaatcttg tttagtatat atttttagaa aaaggagtgg
     9541 ggtttttatg gcagaaatcg tcaaagtcac acatttgaaa aagagctttg gtcgtttcga
     9601 agctttaaaa gatgtctctt tcaccgtaca ttcaggtgaa gtcgttggat ttatcggacc
     9661 aaatggttct ggaaaatcca cgacgattcg gacactttta gggattataa aaaaagacgg
     9721 cggaacggca acgatttttg ggcaagatgt atgggaagat agtttatcta tccatgaacg
     9781 tctttcttat gttccaggcg atatctcttt gtggggaaat ttgactggag gagcgatcat
     9841 cgatctcttc atgaagcttc atggaaaagg gagtgctcaa aaaaaagatg aactgattca
     9901 acgtttctct cttgatccta agaaaaaagc aaaaaactat tcaaaaggaa atcgccaaaa
     9961 agtgggcttg attgctgctt tggctgttga ttcggatctc tatttatttg atgagcctac
    10021 ttctggttta gatcctttga tggaaacgat tttccaagaa gaagttgaaa aattgaaaga
    10081 acagggcaaa tccatcctac tttcttctca tattctcagt gaagtcgagc gactagcgga
    10141 taaagtcgtg atcatacgcg aaggaacact cgatgaagaa ggaacactcg atgaattgcg
    10201 tcatttgact cgttcgacca tcactataga aacagaagca gagaatagtc acttagcaca
    10261 attgaacggt gtccatgact ttgtgcaaaa aggtcacctc gctcaatttg ctgctgataa
    10321 cgaagctttc gatgtgattt tagctgaagc gtccaaatta ggtgtgaaaa aatttgaatc
    10381 tattccaccg actcttgagg atttattcat gagacattat gaaggatgag gaggaagcga
    10441 aatgactgat aaattttcac gctggtccac ccttttttct caaaacctta gccgtgactg
    10501 gaaaaagatc ctgatatggc tagtcggtgt cactgctttt tctggtggtt ttgtccctgc
    10561 gtttgaagaa ttgacttccg gacaaggatt agctggatta tacgaaacct tgcaaaaccc
    10621 ggcaatgatt gcaatggtcg gaccaactcc agcttcgaat gctgctgagt atactttagg
    10681 agcgatgtat gcaaatgaaa tgttgctttt ttgcagtttg tttgctgctg tgatctctgt
    10741 tttacacgtg gtgagccaaa cgagaaaaaa agaagaactt ggtctgattg aacttattcg
    10801 ttcctttcga gtcggacgtc aagcaaactc tttagctgtc atcgctgaaa gtattctgat
    10861 caatttgctt ttagcaatat cgatcagctg tacgatgatt tttttccaag cggattcgat
    10921 cactgcagaa ggtgcttggc tttttgggct atctgtaggt agtatgggga ttttggggag
    10981 tgccgttgca ctgtttgctg cacaactgat gccaagttca gccagttcga atggtctgtc
    11041 tttagcgttt ttaggtggac tttaccttct acgagcaata acagatgtag ctgattcctc
    11101 cctttcgatg tggaatcctt taggctggtc ttatttgacc tatccattta caactaacaa
    11161 ctggattcct ttgctttatt tgtttttgtt cagtctaatc ttgataatca gttcatttgt
    11221 tttagaggaa catcgagatt tgaacaccgg ctatatcccc gaacgtgaag gaaaaccgta
    11281 tgctaaacgt tctcttttat ccttgcgtgg tttattattc tatctaaata aagggatgac
    11341 aatcagttgg cttatcactt ttggtttgat gggggcggca tacggctcta tctacgggaa
    11401 tatgcaacag tttttagaaa gtaacgactt aatgaaacag atgtttatcc aatctggcgt
    11461 ctcaattgaa aaaaacttta caagcacgat catggtcgtc ttgatttgtc tagctgctat
    11521 tttaccaatt gctagcatca atcgtttatt tacagaagaa acccacggac gtatgaatca
    11581 gctgttcgca acaaaaattt ctaggaacca actttattgg accaatatgt tactagctat
    11641 tctatttgct atattggcaa tcctgattag ttctggtgca ctagggcttt ctgctttggc
    11701 ttcgatgaag gatgcgaaag acatggatct attgatgttt cttaaagccg ggttcaattt
    11761 cctgcctgcc gttttagtgt ttatcggaat tagtggcttt ctattcggat ggcttcctcg
    11821 aatcggtaaa cttgcttata tctacttagc ttactccttt gcactcaatt actttggcgg
    11881 aattttggat ttaccagaat ggttttccaa aacagctgtc cctagctggg ttccacggat
    11941 gccaaacgat tcttttgatc tttccgtgtt ccttacgtta tcatgtatca gccttgcact
    12001 gttcgtcctt ggttctattg gttataggcg aagagactta ctagaaggat aataaaaaag
    12061 catgtacaat ttcatgctag cctccaaatc tgggtcaaaa atccaacatt tggaggtcat
    12121 ttttttattt acaagtcttc taactgctct ttatcaatga tccagacttc tcgattcttt
    12181 ctttttacat aaccattctc ctctaataat ttaaattttc tagataaagt ttcgggggtc
    12241 gtaccgataa atgcagcaag ttctttcatt ttcattggca ggaaaaagtg atccttccct
    12301 gtcgctttag ctaagtcaag cagatagaca gcgactcgtt cttctacttt ttccatcatc
    12361 aaaaaagttg tctgctgctg tacttttgtt aatttctcaa cgttgattgc taaaagtttc
    12421 agactaaggg cgggataatg cagtaagagt tccgagaaat ctttttgtct caatatgcaa
    12481 atttccgttt tttctagtgc ttcgccaaat aaagactcat ttggaacgcc tagcaactgg
    12541 ctctctccct catatccgcc cggctctatt actcgtaaaa gctgttcctt tccgctagca
    12601 gataattgat acactttcat actgccggag gccacgatca ctaattgagg ttctccattc
    12661 ggcgcaagaa tctgttctcc tttttccaca tagtgatgtt tgacaagtgc gtgtactttt
    12721 tcttgatctt gctgtactaa gtgattgaac aaaggaacaa atgaaacaca taaatgatca
    12781 tgactcataa tctctcctcc ttctaaacag ctatttctaa taaagaaaca taacttccct
    12841 tattccaact gataattttc ttttatcata gcataaacgt caagcgaacc agataccagc
    12901 aaatagagtg gatttctttt tgtcccttgc tttattttcc ttcttttgag accttaagta
    12961 attgattcct atcaattttt taaatattta ctttttgaat aatcaaaaac aaaccttcac
    13021 tcgcaagccg agagtaaggt ttgtttttcg cattgcttat ttcgtgttgt ctattgaaat
    13081 ttttccgcac ctagcttttg atatagtggt gctagttctt gtaaggtttc agcggttatt
    13141 tgctcaacgt gttcgatttc ttgcggatag aagaatagtt tacccatttg aaaggttcgg
    13201 tctctcatcg cttttttcaa ctcttcttgt ttctttgtat cggacaaata gtcagacaaa
    13261 gctaagtggt cgtcaagttc atgttctggt tgcggccata tgtaataatc cttgatatcg
    13321 actgttttgc tccactcttt cagtatcgca agcaactggt tatacgctgc aatgctacca
    13381 tatcgttctt cgcttttata atgttggtac atcaaataga tttggtattg tttttgattc
    13441 aacaaaactg ctagacaggc attctcgtct tgacgagatt cgcttcggta cgcgctccaa
    13501 aaatgactgc gtaaattcca gccattcgtc cagctttcga ttttaggttt gctcatgccg
    13561 tacatatcag gcaaaagtgc agctgtctgg agctgaatct ctttccattt ttgccagtgt
    13621 tctttatatt ctttcttgat ttgttcaatc ttatctgttg gatggctctc tttgagctgt
    13681 ttgaatgcgt agattggtcg atcaaacaac tgataatctg attttccaag ttccattgtt
    13741 tcgcctcttt ccgttatctt ttgtattcta cctgaatttt gcgatatgga caaatagagg
    13801 ttgtgaaaaa gctgttctgc atcaagtcat aagaacagcc aaacaaaaaa ctgcgatgag
    13861 catcaccgca
//
LOCUS       DAXQKX010000066        13791 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.068, whole genome shotgun sequence.
ACCESSION   DAXQKX010000066 DAXQKX010000000
VERSION     DAXQKX010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.068"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(115..435)
                     /locus_tag="ACF3MF_002254"
     CDS             complement(115..435)
                     /locus_tag="ACF3MF_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFE3928200.1"
                     /translation="MDKYLYLLAGNKIQKSLMDFIQELECTFHKKFTHSILLKLLIHT
                     ACLIERTLINGHELKIISEDDTRPSHETIFHVKKAFKNIETEFGITVSYDECFFIYDI
                     IASK"
     gene            736..2616
                     /locus_tag="ACF3MF_002255"
     CDS             736..2616
                     /locus_tag="ACF3MF_002255"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFE3928201.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIIIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDNVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDQFSQYYTPTVLLIALLVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQRGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAMLKQAGAKHLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLH
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSSFGSLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLIGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            2695..2922
                     /locus_tag="ACF3MF_002256"
     CDS             2695..2922
                     /locus_tag="ACF3MF_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HFE3928202.1"
                     /translation="MKKMIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSTKVKEA"
     gene            2927..3469
                     /locus_tag="ACF3MF_002257"
     CDS             2927..3469
                     /locus_tag="ACF3MF_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008199 - ferric iron binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin-like domain-containing protein"
                     /protein_id="HFE3928203.1"
                     /translation="MNIVEEKFAQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLKQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            3720..4397
                     /locus_tag="ACF3MF_002258"
     CDS             3720..4397
                     /locus_tag="ACF3MF_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HFE3928204.1"
                     /translation="MGLAFLLAGCTNGNESKKESTKETAKATIATTTTTSTESKPTAA
                     STETADTSTSSESSKTTETTQTSTSSSSVEASSSESSEQVEQTLWNADKSAQLEAFMA
                     TWGQTMGQQYKSYTNQMSVDLYGLKVPQVILNGEWKMAIGGVPVSAEWSESGTGQADY
                     QITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNETANNELKNG
                     FNQIVYG"
     gene            4739..5959
                     /gene="sstT"
                     /locus_tag="ACF3MF_002259"
     CDS             4739..5959
                     /gene="sstT"
                     /locus_tag="ACF3MF_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HFE3928205.1"
                     /translation="MSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSCLKAIAPI
                     LVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPITLQETVSE
                     KAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEPTKELVDQI
                     SIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLFVALVVYP
                     FLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKESYSISIP
                     LGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGVAGGSLLL
                     IPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELGARKRSGE
                     KIKLKDCLDGLSER"
     gene            6106..6741
                     /locus_tag="ACF3MF_002260"
     CDS             6106..6741
                     /locus_tag="ACF3MF_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HFE3928206.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            6932..7675
                     /gene="truA"
                     /locus_tag="ACF3MF_002261"
     CDS             6932..7675
                     /gene="truA"
                     /locus_tag="ACF3MF_002261"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFE3928207.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYRS"
     gene            7909..8742
                     /gene="msrA"
                     /locus_tag="ACF3MF_002262"
     CDS             7909..8742
                     /gene="msrA"
                     /locus_tag="ACF3MF_002262"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFE3928208.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDTRENISVKEQ
                     LSKLEVTLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQDERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            8823..9816
                     /locus_tag="ACF3MF_002263"
                     /pseudo
     CDS             8823..9816
                     /locus_tag="ACF3MF_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328323.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
     gene            10105..10803
                     /locus_tag="ACF3MF_002264"
     CDS             10105..10803
                     /locus_tag="ACF3MF_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="HFE3928209.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNIA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNVLAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            10953..11408
                     /locus_tag="ACF3MF_002265"
                     /pseudo
     CDS             10953..11408
                     /locus_tag="ACF3MF_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            11489..12615
                     /locus_tag="ACF3MF_002266"
     CDS             join(11489..11717,11717..12615)
                     /locus_tag="ACF3MF_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFE3928210.1"
                     /translation="MTRYEENFKQMIIELNQTGRSVRGLAKEYGLSEATIYKWKNLYL
                     PDQSTGLTGKEVAELRKENARLNEELEILKKAGSHILSENLNSLVQFIEKWCKDYTVS
                     LLCRLLEIPRSVYYFYKNKPLTATEIRNNKLKKKISTIFFTNKQRYGATKIHQVLLKE
                     GISVSLKHVQKLMKQLNLRSIVVKKYRPQRSNKPIILKENLLNQDFSTETICEKWAAD
                     ITYIPTKKNGWCYLSSIMDLHTKKIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMIL
                     HTDLGSQYTAREVEQWLKTNKIRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDF
                     EEANRALFSYIEGFYNRNRIHSSIHYLTPQEFEELAKEKMA"
     gene            12660..13616
                     /locus_tag="ACF3MF_002267"
                     /pseudo
     CDS             12660..13616
                     /locus_tag="ACF3MF_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
BASE COUNT         4626 a         2225 c         2835 g         4105 t
ORIGIN      
        1 gtaaccgata cattagtttc aatgtttact gagtaactaa ttattttgca ggaggacaat
       61 ttatttacac aaaattattg acgctcccaa aatactcgtt tacataaaaa aagattattt
      121 agatgcgata atatcataga taaagaaaca ttcatcataa gaaacagtga tcccaaattc
      181 tgtttcaata tttttgaagg ccttttttac atgaaaaatt gtttcatgag aaggtcttgt
      241 gtcatcttct gatataattt taagttcatg accgtttatc aatgtacgct caattagaca
      301 cgctgtatga atcaaaagtt ttaaaagaat ggaatgagtg aattttttgt ggaaagtaca
      361 ttccaattct tggataaaat ccattaagct tttttggatc ttattcccag ctaataagta
      421 gagatatttg tccactgctt caactcccat atcaaaaaac gatatttctt gtgaatgagt
      481 ggctgctgcc cttttttgat tgttgttctt cagtcgtaag atgacaaagc atcttatctt
      541 tgaataaaaa aatagaacta cctaaggaag cgtttcggcg cttccttttt ctatatgatc
      601 gtttaatgac tgtaggaatt cagtatacca aaagaaaacc gcctttttga ataaacttga
      661 tagtggtcaa ttttttatga tggataagta tctatactta gtctcgtaag aatgaaaagg
      721 aaaagaggga gaaagatgaa attacaaaag tggatccaag agcatcgaaa tcatatcacc
      781 gccttatcag ctgtgttgat tatttttggt tttatcggga aatttactgg atttgtcttg
      841 ttctataaca ttgctctagc catagcttct attattgcgg tcatacctat tataatccat
      901 gcgtatcagg cagtaaaagt caaagttatc tcaattgatt tactcgttac tattgctgtg
      961 cttggtgcct ttatgatcgg agaatacaag gagtcagcta tcgttacatt cttgtttttg
     1021 tttggtagtt atctggaaca aaaaacattg accaaaacgc gggaatcaat caaggctttg
     1081 accgagatgg ccccatcgac tgccagcgtt gtccaagaag atggaacgac cgaagaagtg
     1141 gaaatcgatg acgtggaaga aggcgatatc gtcttagtaa aaactggtgg agctattcct
     1201 gtggacggac gagtcattga cgggaaaggg tatgcggatg aagccgcagt gacgggtgaa
     1261 tcacgacaag tcgtcaaaat cagtggagat aacgtatttt ctggaacgat tttagcagat
     1321 ggctacgtga cgatcgaagc aactaaggtc ggagatgata cgacctttgc caaaattata
     1381 gaattagtcg aagaagcaca agataccaaa tcacatgcgg aaaaattcat tgatcaattt
     1441 tctcagtatt atactccaac cgttttactt attgcgttgc ttgttggtct gatcagtcgt
     1501 gattttcgtt tagccatcac tgttttggtt cttggttgtc ctggcgcttt agtcattggt
     1561 gcgcctgttt cgaatgtagc aggaatcggt aatggagcga aacggggcat cttagtcaaa
     1621 ggcggtgaag caatggatac tttttccaaa atcgatactt ttgtctttga taaaaccggt
     1681 acattgacca aaggaactac tgctgtatcc actatcaaga actatacaga ggatgaaggg
     1741 gacagcttag ctttagtggc tcgattagaa acgttatccg atcatcctct ggggcgcgcc
     1801 gtgatccatt atgctcagga gaaagacatt gattttcaac aattagcagt caaagataat
     1861 cagacgatca agggacaagg aatcacagct gagattgatg gtcatacagt ttgtgcgggc
     1921 aacaccaaat tgattgccgc tcacaaactt tctctcacac caaagcaagt acaagattta
     1981 catcaattac aacaaagagg cagctcagtc attattgtag caatcgacaa aaaaatcact
     2041 caaatcattg gtgtgtcaga tgtgattcga ccagaagtcg ctgaacaatt agctatgttg
     2101 aaacaagcag gagcaaaaca tttagtgatg ctgacaggtg ataatcagat gactgctgat
     2161 tatgtagctg acatgttagg cattgatgaa gtccatgctg aattattgcc agatgaaaag
     2221 gttcaatttg tgaaaaaata ccaagaacaa ggattgcacg ttgctttcat tggagatgga
     2281 atcaatgatt ctccctcttt ggctgcggct gatatcggga ttgctatggg atcaggaacg
     2341 gatgtcgcta tcgaaacgag tgacgttgtc ttgatgcaat ctagttttgg atcgttggtt
     2401 catgcttacc gtttggctaa gaaaactgtt ttgaataccc gtgaaaatgt agtgattgcc
     2461 attggtgtcg tcttattttt actcatcggc ttatttgccg ggtttattta catggctagt
     2521 gggatgttcg ttcacgaagc tagtatcttg atcgttatct ttaacgcgat gcgtttattg
     2581 tattttggac acgaaagcaa agaagaaaaa tcgtaaaact tgataagaat caattttttt
     2641 atggaagctg taatctagaa taagactatc aagaaaaagg aaggaagaac tacgatgaaa
     2701 aaaatgatta tgcaattaga tacactagct tgtccaagct gtatgcaaaa aatagaacat
     2761 gcggtttctc aacagcctgg ggtaagcaat acgaaagttt tgtttaatgc gagcaaaatc
     2821 aaagcaaact ttgatccaga tgaagtccac cctgaacaat tagctgcagt tgtggaaaaa
     2881 ttaggttatg aagtccaatc aacaaaagta aaagaggcgt aaatcagtga atatagtgga
     2941 agaaaaattt gctcaagaaa caaaacaagc agatatcgat catcataaac caactgctgg
     3001 cgccatggtg gggcatgtat tggcaaattt taaattagaa gaaatgaaat tgatccaagc
     3061 acaattgtat gttttgggta catcttcgca agaattaagt accctttttt cagaatatgc
     3121 tgatcaagaa gcgagatggt tcaataaaat ctctcatgag ttagtgattg aaaatgaaat
     3181 cgttccgtct actttagaag aagtcatgcg ttatggaaaa atttacgaac atggtcaaaa
     3241 caaatattta ccagcctcaa caatgttgga aaactttgca aaagattttg atttccaaaa
     3301 tgtctttatc acacgggcaa tcaaattagc tgaaaaagaa gaaaaatatg gcttgaaaca
     3361 attgcttgtt gaacttttaa gtttcaataa agaaatcatc taccaagtac aaagactcca
     3421 aggaaaaact gtccgacaag atttggatga ggaagacgat gatgactaaa agtctatgtt
     3481 tcttcaaata caaatataaa gcgtgaggta aattggaaaa tcgcgaagat taaaataaaa
     3541 gaagcacccg ctgatgtatt acagacaaca tcagcgggtg cttcttagtt tttaaaaggt
     3601 ttaaaagatg gatgagaaaa tacaaaaaat caataaaatc acattgctta tttgatagaa
     3661 taaagaagtg ggagtaatcg aaaggagttt tttaatttaa aaaaaggatt ttagtaacaa
     3721 ttggtctagc ttttttgtta gctggttgta ccaacgggaa tgaatcgaaa aaagaatcaa
     3781 caaaagaaac agcgaaagca acaattgcaa ctactacaac aactagcaca gagagcaagc
     3841 caactgcagc aagtacggaa acagcagata cctctacttc gtcagagtct tccaaaacga
     3901 ctgaaacaac tcaaacatct acttcaagtt cttctgtaga ggcttcatct tcagaaagca
     3961 gcgaacaagt cgaacaaaca ctgtggaatg cagacaaatc cgcacaatta gaggcattta
     4021 tggctacatg gggccaaaca atgggacaac aatacaaaag ctatacgaat caaatgagtg
     4081 tggacttata tggtcttaaa gtccctcaag ttattttgaa cggggagtgg aagatggcta
     4141 ttggtggagt gcctgtttct gcagaatggt cagaaagtgg gacaggtcaa gcagactatc
     4201 aaatcacagc cgtctattcc gatgcagaga cagaaccata tctgaaaaag cacgtctatc
     4261 tattcgggtt tcagcaaaat cagccaaaag tattggtgac acaacaaaat caggggaatc
     4321 ccgataatta tctttacttt aacgagacag cgaataatga attgaaaaat ggctttaatc
     4381 aaatcgttta tgggtaagta aaccagtgag agtgagagaa agaagagact cagtggaaaa
     4441 tattaattga ttgctatgtc taagaattaa gatgaaggat gaaatttcta gtttcgtcct
     4501 tcatcttagt tacgttttac ttggataact ataataataa cgataaatag ttttctctcg
     4561 acttctttag agattgaata aaccctccaa tactaaaatt gaatgttgca agagcatgaa
     4621 ttgccaattg tattattaga atttttagaa aattgcacct ttagtttctt tagataaaat
     4681 gatacaatga ttgttaaaat tgtgaaaggg tggtcatttg ttagagaagt ttttggatat
     4741 gtcgttagtt caacgtattg ttgttggtat tttagtcgga atattgtttg gtatcttttt
     4801 ccccacgtgg acatttattt caatattggg gacgttgttt gtcagttgct tgaaggcaat
     4861 cgcacctatt ctggtttttt tcttgacgat ggcgtcaatt gccaagcata aaattgggaa
     4921 taagacattc gtgaagccta ttttgatctt atatttagtg ggaacattgc tttctgcact
     4981 tgtagcagtc attgtaagtt caatttttac tgttcctatt actttacaag aaacagtatc
     5041 tgaaaaagca ccgcaaagtt tggaaagtgt tttatctact atgttgacga atgtcacaca
     5101 aaatcctgtt caatctctta ttgatgcgaa ttaccttggc gttttattct gggctgtatt
     5161 gttgggacta gcttttcgag cacgttcaga accgacaaaa gagttggtgg atcagatatc
     5221 tatagcgttg tcacaagtcg tacaagtgat tattgcattt gctccgatag ggattttagg
     5281 attggtttat caatcaattg ctacgactgg aatcgctgga ttggcagagt atctgcagct
     5341 tttacttgtt ttgatcggta cgatgctgtt tgtcgcatta gttgtgtacc cattcctcac
     5401 gtttttgttt attaaagaaa atccctatcc attgattttc ttttgtttga aagaaagcgc
     5461 acttcccgct ttctttaccc gaagttctgc cgcaaatatc ccgataaaca tgatgttggc
     5521 tgaaagattg aaattgacaa aagagtctta ttccatatcg atcccgttag gtgctacgat
     5581 caatatgggc ggtgccgcga ttaccatttc cttgatgacg ttgactgctg tacattcttt
     5641 agggattgaa gcaccatttg ttttgaaagt ccttttatgt attttgtctg ctttagctgc
     5701 ttgtggagct tcaggtgttg cgggcggttc actgttattg attccattag catgtagttt
     5761 gtttggtatc tctaatgatg tcgcgatgca aatcgttggt attggattta ttatcggtgt
     5821 tatccaggat tcaatggaaa ctgccttaaa ttcgtcaagt gatctgttgt ttactgcaat
     5881 aggagagcta ggcgcgcgta aaagaagtgg ggaaaaaatc aaattgaaag attgtttaga
     5941 tggattaagt gaacgttgaa cgttagatat ttagtatttt taaaatgatt cgagttttta
     6001 atgagttata tagatgttcg tgtaaataga ggtttctgtt aaatcaagat aaagtcgttt
     6061 ataataacaa ttaaaagcat aggtaattgt tattggaggc gtatcatgga ttttttacgt
     6121 aaatttggtt ttttcttttt attattaggc gtgctgagtg attttttgac tccgtacgta
     6181 ttaggattgt attatcctga attagatcaa atgaagagcg tgatcagtgt atttggagag
     6241 gtttccagtc ctgtaagaaa agcgtttctt atttggtctg tggtttcagg gatctttttc
     6301 atcctgtcat tgcctgcatt gtatgctgca tttgtaagta catctcgtgt gttagctacc
     6361 ctagttacag cagccatcgc gttctatggt ataggtgatt gtatctttac aggtttgttc
     6421 agtatcaata cccatgaatc ttcgtggaat gtctcgacat gggtccataa tatcggatca
     6481 ggtttaggtt acagtggttt tttattgttt ccagttcttc ttttcttgat ctatcgaaaa
     6541 aatgggcaaa tggacgtaag ccacttatac cttggactgt ctgtgatcag tttgcttttt
     6601 gcggcgattt atggactggc aagaattcct tctataaatt cttggccatt actgaataaa
     6661 ataggttttt gccaaagaat cagttttttc tttaattatg tgcccattgc ctggttgagt
     6721 atcttgcatc tcaaacagta aaacttgagc cgtcaaattg aacagtcagc ggatacttca
     6781 tccggtggct gttttttgtt tttctgaaat atatatttcc acagttttct tgtatagctt
     6841 ctgtcttaga gaagcaagga gctatatttt gtgctacaat cttaaaaagg tagagagaag
     6901 accaaatgga agacagagga gccactaaaa tatgagaaac atcaagttga caatcgaata
     6961 tgacggaaaa agatattcag gatggcaaag acttggagat gacgataaaa ccattcaagg
     7021 aaaaatcgaa aaagtattgc atcagatgac aaatgaagag atagaaatta ttggatcagg
     7081 aagaacagat gctggcaccc atgcgcgagg acaagtagca aattttaaaa caaacacaga
     7141 aattggactg gcagaaatga tcgactttat gaatcgttac cttccgcggg atattgtcat
     7201 caaaagaatc gaagaaatgc ctgagcgctt ccattcaaga tataatgcgg tgggcaaaaa
     7261 atacagctat tatgtttgga acaacgtgat tccttcagca tttgagcgaa accacagctt
     7321 ttatttccct caagagttgg atatggacaa gctgaatgca gcttgcgaaa aattagtggg
     7381 tacacatgat ttcattggtt tttctgcatt gaaaaaatca aaaaaatcca cagtgcgtac
     7441 gattgatgaa ttatctatcg aacgaaaggg agaaatgctt cattttactt ttgtcggaga
     7501 cggattctta tataaaatgg tgcggattat catggggaca ttactagaaa tcggcacagg
     7561 tgccatgccg atagaaacaa tcgatgaaat atttgaaagc aaagtgcggc aacatgcagg
     7621 agaaaccgtc cctgcacaag gtctgttttt ggatgaagtt tattatcgct cataaaaaag
     7681 aatcatcttt actcgacttc tgagaattgg agaacatccc ttttttcaga ggtcgttttt
     7741 tagttaaacc aaaccataga gtatgctttt taagataaag atcatcttat atcatctgaa
     7801 gctgcttatc ttctttgaat aaatacgatt caatcgatta tttcctcact ttatgataaa
     7861 ttacagctaa agtcactagc ttgtcttctt cggaaaggag gagaatctat ggatgaggaa
     7921 caaatattca ttcaaacact ttataatctg attttgaatc cgaatacacg agattgggaa
     7981 cgaaaagtat tgattcagac aaagaatgac acaagagaaa atatatccgt taaagaacag
     8041 ttatcaaaac tagaagtaac actacgtcca ttagctatcc gaatgaatct gacgcctgat
     8101 gtaatggact tttatttatt gattacggaa ggatttgata aggagcaaaa atatgacttt
     8161 tccaagcatg ccatgcaaga tgctgactat caagaacgtg cagtatttgc agggggatgt
     8221 ttctggtgta tggtcgagcc gtttgaatcg aaaaaaggga tcctatctgt tttgtcagga
     8281 tacacgggcg gacatgttga aaaaccgaat tatgatcaag taagtggtgg ttacacaggt
     8341 catgtggaag ctgtggagat catttatgac acaagagaaa taagttatag cgagttgctg
     8401 acaatctatt ggcaaattac tgatcccaca gatacatttg gacaatttca agatagaggg
     8461 aagcaatatc gtccagtgat tttttatcaa gacgaacgac aaaaagaatt agcggaacaa
     8521 tcaaaacaga aactagacag ttcaggaact ttccaccaac caatcgtcac aaaaatcgaa
     8581 ccagccggta cgttttggcc agcagaaaac tatcatcagc aattttacaa aaaacaaccg
     8641 aaacgctata aaaaaatcca gcaagcacgt aatcaatttc tgatctatca acgagtaaaa
     8701 aacaaatggc aaaaaaatat acgaaaaaat cattttgatt aactcctttt ctttaaaatg
     8761 tagtaaacta aaaatagaaa acaagaaagc gttttaaaaa gatttgatga ggaggagaaa
     8821 aattgtatat tgcagatagt gcacgttatg aaaaaatgga atatcgtaaa tccggtcatt
     8881 caggtttaaa attaccgatt ttatctctcc tctcggatta tggcaaaatt ttggtgatta
     8941 tgatcctatc cataatcaaa gagagatttt aagaggcgca ttcgacatgg gaattaccca
     9001 tttcgacctt gcgaataatt atggaggccc tgctggagct gcagagaaaa actttgggcg
     9061 tatttttaga gaagattttc aagcctaccg tgatgaactg attatttcta gcaaagcagg
     9121 ttatcatatg tgggaagggc catatgggga atggggctct cgtaaatcca tcatatcaag
     9181 ttgtgaccaa agtttccaaa gaatggggct agattatgtt gacatcttct atcatcatcg
     9241 cccagaccct gatacacctt tggaagaaac agcagaagcg ttgatgcaac ttgtaagaca
     9301 aggaaaagca ttatatattg gtatatccaa ctataatgga gaagatacaa aaaaatgact
     9361 gaaattttaa aaagaaagga agcaccgttc attattcatc agatgcgcta caatatgttt
     9421 tctcgtgcac tactagaaga cgatctatct ccagtattag aagaagaagg gctaggggca
     9481 atcacgttca gtccgcttgc tcaagggttg ctgacaaatc gttatctaca tggtattcct
     9541 gaagattcta gagcacatcg taaggaaata ccattccttt cagaagaaca agttggatca
     9601 actctggaaa aaatcaaagc actgcaaaca atcgccgtat cacgaggaca atcattagcg
     9661 caaatagccc ttgcatggaa tttacgacaa aaatctgtta caagtgtact gatcggagca
     9721 agtcggttaa gtcagttaca agaaagtgtt cgaatgatgg ataatttaga tttctcacca
     9781 gaagaagaat tgagaatcga ccaaattcta gaatagaaac gatgtaatca aactttttat
     9841 ccatatatta aaaaaaacaa aagatgacat caagaatcga atgaagatcg tctgttattg
     9901 aacatcatat tttttgtcga tcaaaataaa aatgatcgaa ggctaggagt gaattttatc
     9961 ctagtctttt ttatggtaaa tatcttcttc gtttgtatgt ctatgaacgg attaatcgat
    10021 tttttataca aaaaatcatc agatgattca aacgtgttat aataattacg aaaaaataca
    10081 tcagatgaaa aggaggtatg tggtttggaa gaaaataaaa ccctagtaga agtaactact
    10141 gacaagatcc ttagatattt aaaggaaatg cagttgcaag taggagataa actgccgaat
    10201 gaatatgaat tgtccgatta tttagaggtg gggcgaagca cggtgcgaga agctgtgcgg
    10261 gctctagctt ccaggaatat ccttgaagtt cggcaaggag cggggacatt tgtcagtgat
    10321 aagcgaggga ttgccaatga cccactcggt ttttctttga ttgaagatca ggatcggatg
    10381 atacgagact tatttgaact gagatattta ttggagccta agatggcagg tttggcagcg
    10441 gaatatgcaa cgaagaatca aatcgtccaa atgaaaaaat taacgcaaaa gattgaaact
    10501 tcttttcgag aaggcacaca agaacatgtt caattagaca tcgattttca tacgatgatt
    10561 gcagaagcta gcggaaacat agccttgctg catattatcc caatcattaa tgaatcgatt
    10621 gctttgttta ataaaaatta tgatatccag catctgaaaa tcgagacgat cgatattcat
    10681 acagagatcg ttcaggccat cgaaaggcgg aacgtacttg ctgcgtttga cgcaatgact
    10741 gtccatatgg caataaatcg gagagaatta cagaaaataa taggagaaaa agaaactaat
    10801 tgacagttca tctgatgtat tttatgataa atacatcaga tgattttttg ttttatattt
    10861 ggtaaaaaag aggagtaaat agtttctgtt caccaaaatg taagcgctga ctaatagaca
    10921 aaaagagatg acgtcaagga gaagaagcag gaatgagggg atctggaatg agttttatgg
    10981 ataaattagc caaagtttta gggaacgtgg caacgagaat caataattta aggtatatca
    11041 tggtgataaa aaacgcattt gctgcattga ttccggtaat tattacgggt gcttttggca
    11101 cattgttttc agcaatggtc tttgactcgg aaaatggctt agcacagata agttacttgc
    11161 gttttttaga agaattaaag cctatcgcat ctgccatcag ctatgtcaca ctaagtttct
    11221 tgaccatcta tgctgttttt ctaataggga tcgaattagc caagctgaat aaagtggatg
    11281 gtgtattccc tggtatcatc gcagtgatgt cttatttatc tgttaatcca actgtttatg
    11341 aattagtgaa tgaaaatcag actgttatag tagaaaacgt attggctaaa caatatacag
    11401 acacgaaagt ggtgttagta tcaaatctta gacagctttt cgtagagaca agaataaatt
    11461 aaacttatct acgagaggat gaatttttat gacccgatat gaagaaaatt ttaaacaaat
    11521 gattattgaa ctgaatcaaa ctggacgttc tgttcgaggg ttagcgaaag aatatggctt
    11581 atctgaagca acgatttaca aatggaagaa tttatattta cctgatcagt ccacaggact
    11641 gactggaaaa gaagtagctg aactgagaaa agaaaatgct cgtttaaatg aggaacttga
    11701 aatcttaaaa aaagccgcag ccatattctc tcggaaaacc taaattcgct tgttcaattt
    11761 attgaaaaat ggtgtaagga ttacactgtt tctttgttgt gtcggttatt agaaatccct
    11821 agaagtgtct attattttta taagaataaa ccgttgacag ctacagaaat cagaaataat
    11881 aagttgaaaa agaagatttc aacaattttt tttacgaata aacaacgcta tggtgccaca
    11941 aagatccatc aagttttatt aaaagaaggg atttcagtat ctcttaaaca tgtccaaaag
    12001 ctaatgaaac aattaaattt aaggtcgatt gtagttaaaa aatatagacc tcaaaggtct
    12061 aataaaccga tcattttaaa agagaatctc ttaaatcagg acttttctac tgaaacgatc
    12121 tgtgagaaat gggcagctga cattacgtac attcctacta agaaaaatgg ttggtgttac
    12181 ttatcttcaa tcatggattt acacacgaaa aaaattatta gttatacatt ttcaaaacga
    12241 atgactgtgg attgtgtcat tcaaacattg aataaagcaa aaatacatta tcacattcca
    12301 gaaggaatga ttctacacac tgacttgggc agccaataca cagcaagaga agtggaacaa
    12361 tggcttaaaa ccaacaaaat aaggcattct tatagtagaa aaggaacacc ttatgataat
    12421 gctggaatcg aatctttcca tgcctcattg aaaaaagaag aagtctacac gactagctac
    12481 tcagattttg aagaagcaaa tcgagcgcta tttagctaca ttgaaggatt ttataaccga
    12541 aatcgaatcc atagctcgat tcactatcta accccacagg aatttgaaga attagcaaaa
    12601 gaaaaaatgg cttaaccgtc tctactaaaa tgtgtccaag atattgactc aaatccattg
    12661 atcgttacgg tgatagggta aaaaactggt ttacattcaa cgaaccaatc gttccccaaa
    12721 cgcgttgcta tttggatgct gttcgctggc cgcatgaaca aaacacaaaa aagtggatga
    12781 tgtggaatta tcataaagtt ttagcaacgg ctaaagcagt agagatttac cgcagcggaa
    12841 attatggtgg aaggattggc tgtattttaa atcctgaaat ggtctatgct cgatctaatt
    12901 ctccagaaga ccaaaaagct gcttatatgt atgatttgtt ttataatcga gtattttttg
    12961 atccgatggt aaaagggtac tacacagaag agttcctgga gttgtgtcaa aaacaatcga
    13021 tttatttcga tcctgcaaca gaggatttag aaacgattca gcatcataca gtagatttcc
    13081 ttggaatcaa tcaatattat cctaaacgcg ttcgcgctcc tcgttatcaa tggaatgaag
    13141 agacaccttt ccatccagaa cgatattatg aagtctttga tttacctggg aagaaaatga
    13201 ataattccag gggatgggaa atctatccga aaatcatgta tgatatagcc atgtatctaa
    13261 aagaaaatta tcataatatc ccttggctga taacagaaaa cggtatggga agagaacatg
    13321 aagaacggta tatggatgag aaaggaatcg tgcaagatga ttaccgtatc gaatttatcg
    13381 gacagcattt gcgttatttg atcaaagcaa cagaagaagg cgcaaattgc gaaggctata
    13441 tgttatgggc attcactgac tgtgtgtcac caatgaatgc atttaagaat cgatatggat
    13501 tagttcgaat cgaattgaac gatgaacgaa gcagaacatt gaaaaaatct gcttcgtggt
    13561 atcagacttt gattgataag agagaattgg atttgcctga cgaaatctat aaataaatag
    13621 aagttttttg tagatgttca ttgtatttac tggttatttg aaataaaaga ggttgtgaaa
    13681 aagctgtcct gcatcaagta ataagaatag caaagtaaaa acaacatctt atgtttttaa
    13741 cttggttgga cttattaccg cagatgcaag cttttgaata ccgtttattc g
//
LOCUS       DAXQKX010000067        13778 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.069, whole genome shotgun sequence.
ACCESSION   DAXQKX010000067 DAXQKX010000000
VERSION     DAXQKX010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13778
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.069"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(12..1022)
                     /gene="trpS"
                     /locus_tag="ACF3MF_002268"
     CDS             complement(12..1022)
                     /gene="trpS"
                     /locus_tag="ACF3MF_002268"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HFE3928211.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            1276..2013
                     /locus_tag="ACF3MF_002269"
     CDS             1276..2013
                     /locus_tag="ACF3MF_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFE3928212.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTELHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            2027..2842
                     /locus_tag="ACF3MF_002270"
     CDS             2027..2842
                     /locus_tag="ACF3MF_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFE3928213.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            2855..3502
                     /locus_tag="ACF3MF_002271"
     CDS             2855..3502
                     /locus_tag="ACF3MF_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFE3928214.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            3518..4174
                     /locus_tag="ACF3MF_002272"
     CDS             3518..4174
                     /locus_tag="ACF3MF_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFE3928215.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            4336..5157
                     /gene="racE"
                     /locus_tag="ACF3MF_002273"
     CDS             4336..5157
                     /gene="racE"
                     /locus_tag="ACF3MF_002273"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HFE3928216.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            5160..6515
                     /gene="rph"
                     /locus_tag="ACF3MF_002274"
     CDS             5160..6515
                     /gene="rph"
                     /locus_tag="ACF3MF_002274"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0009022 - tRNA nucleotidyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HFE3928217.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            6516..7034
                     /locus_tag="ACF3MF_002275"
     CDS             6516..7034
                     /locus_tag="ACF3MF_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFE3928218.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            7141..7641
                     /gene="cbpB"
                     /locus_tag="ACF3MF_002276"
     CDS             7141..7641
                     /gene="cbpB"
                     /locus_tag="ACF3MF_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HFE3928219.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(7921..8841)
                     /locus_tag="ACF3MF_002277"
     CDS             complement(7921..8841)
                     /locus_tag="ACF3MF_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HFE3928220.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            8967..10019
                     /locus_tag="ACF3MF_002278"
     CDS             8967..10019
                     /locus_tag="ACF3MF_002278"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HFE3928221.1"
                     /translation="MIKCGENNEGGKYMQIDWNNLGFSYIKTPWRFIAKWKDGQWEEG
                     ELTEDNYLTIHEGSPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLM
                     PMVPEKMFVDAVKQVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVF
                     CTPVGAYFKGGLKPTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCV
                     YLDPATHTKIEEVGAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIE
                     GDIFIDDLDQFAEAGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGI
                     QFGDIEAPEGWIEVVE"
     gene            complement(10129..10884)
                     /gene="fabI"
                     /locus_tag="ACF3MF_002279"
     CDS             complement(10129..10884)
                     /gene="fabI"
                     /locus_tag="ACF3MF_002279"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HFE3928222.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            11104..11544
                     /gene="fabZ"
                     /locus_tag="ACF3MF_002280"
     CDS             11104..11544
                     /gene="fabZ"
                     /locus_tag="ACF3MF_002280"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFE3928223.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(11659..12420)
                     /locus_tag="ACF3MF_002281"
     CDS             complement(11659..12420)
                     /locus_tag="ACF3MF_002281"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFE3928224.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            12609..13703
                     /locus_tag="ACF3MF_002282"
     CDS             12609..13703
                     /locus_tag="ACF3MF_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HFE3928225.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
BASE COUNT         4402 a         2420 c         2869 g         4087 t
ORIGIN      
        1 gagtaaatga attaatggaa gtaattgatt cccattgctg attttacttc agaaagtgtt
       61 tgtgcagcta ctttagcagc ttcttcacta cctttacgta agatttccat aacagctgaa
      121 ggatcttttt ccaattcttc tcggcgcgca cggatcggtg caaattcagc ttccaataca
      181 tcaatgaggt atcgtttgat ctttacatca ccaagtccgc cgcggcggta atgagctttc
      241 atttcttcaa ttgcttcttt atctgttccg aatacatcca agtaggtgaa gaccatattc
      301 ccttctactt gtccaggatc ttgtacatgg atgtggtttg gatcagtata catactcatg
      361 acttttttct gtaagacatc ggcaggatcg gagatataaa taccgtttcc taacgattta
      421 ctcattttgc catttccatc gattccaggt aatctaccca ttccttttgg tgggaatacg
      481 ccttttggtt ccaccaagac ttcaccatat gtatgattga agctttgtac gatttcctgt
      541 gtctgctcta gcattggttt ttgatcctca ccaacaggta caagattcgc tttgaatgca
      601 gtgatatctg ctgcttgaga aacaggatag ataaagaatc ctgtaggcac gctttcaccg
      661 aatttttttt gttcgatttc tgttttgaca gtcggattgc gccgaacgcg tcctacgctg
      721 actaagttca aataatacat ggttaattca gctaattccg gaatttgtga ttggataaat
      781 aaagtagatt ttgcaggatc taatcccacg gctaaatagt ctaaagcaac ttgcaagaca
      841 tttgatgaaa ccttctcagg atttttagca ttatctgtca gtgcttgcat gtcagcaatc
      901 atgacaaaca gttggttgtc ttcatctgcc tgcatagcca ctcgggtttt tagagaaccg
      961 acgtaatgcc ctaaatgcag cttcccagtt ggtcgatctc ccgttaaaat aatatttttc
     1021 aaaaaagaca cctctttacg atttgtaagt ctgagcactt aatatcttac cgtttttcct
     1081 gaaaagaaac aacagttcct aaggaaaaaa caaggaaaga ggataaaata actaatagat
     1141 tagaaatgga agaaatattt atgggagaat aaacgttcta agaaacttta caaattacta
     1201 aactatcaga tataatgtat tttattatac atctttaaaa gaaatcttac taaataataa
     1261 tgggagtgta attctatggc aatgattaaa tttgatcacg tggataaata ttatggcaag
     1321 ttccacgcat taaaaaatat caatctcgaa ttcgagaaag gagaagttgt cgttgtcatt
     1381 ggtccttctg gttcaggaaa gagcacgatg cttcgctgta tcaatggatt agagacgatc
     1441 tcttcaggta agctgctgat taatgatact gagttgcatg ataaaaagac aaaactgaca
     1501 gaagtccgaa aaaacatcgg catggttttc caacatttca atttgtaccc aaataaaact
     1561 gttctggaaa acatcaaatt agcaccaatc aaagtgttga agcaagacca ggcaactgca
     1621 gtcaaaaacg cggagaaatt tttgaaaact gtcaatatgt tagataagaa agattcttat
     1681 ccttccatgt tatccggggg acaacagcaa cgggtggcaa tcgccagagg tttagcgatg
     1741 aatcctgaga tgctgctgtt tgatgaacct acttctgctt tggatccgga aatgattggt
     1801 gatgtattag acgttatgaa aaaattggct catgacggta tgtcaatgat tgtcgtgaca
     1861 catgaaatgg gctttgccaa agaagtggcg gatcgtgtta tcttcatggc tgatggagaa
     1921 gtattggaag acagcagaaa tgtgagagac tttttcgaaa atccaaatga agtccgagca
     1981 cagcaattta tcagtaaagt tatcaatcat tgataggagg aaaaagatgc gcaggttaaa
     2041 aaaaatacgc ctgattttcc ttttaggcat tgcttttctt gcactagccg gatgtaaagg
     2101 aaatgggttg gcaaatgaag atattttaga gcgaagcaaa tctaccaatg aaatcatctg
     2161 gggtgtcaag tatgatactc gattatttgg aatgatggat attgagagca gaactgtaca
     2221 aggatttgat gtagatattg caaaagcaat cactaaaaag atccttggtg acaatggaaa
     2281 aacagaattt gttgaagtca cttctaaaac tcggattcca ttattgaaaa acggaaatat
     2341 cgatgcaatt attgcaacga tgacgatcac agatgaacga aaaaaacagg ttgacttttc
     2401 agatgtctat ttcgatgctg gccaagcttt gttggtaaag aaaggaagcc aaatcaaaag
     2461 tgtagatgat ttgaatgctt ctacaacggt tctagcagtc aaaggttcta catcggctgc
     2521 gaatatccga cagcatgcac cagatgcaaa aattttagaa ttagaaaact atgcagaagc
     2581 atttactgct ttacaatctg gtcagggaga cgcgatgact acggataatg cgattttgtt
     2641 agggattgca gatgaaaatc cagagtatga gttagttggt ggaacgttta ctaatgagcc
     2701 ttacgggatt gcgatcaaca aagggcaaga aaacttcttg aaagctgtta accaagcgct
     2761 agaggaaatg catgcagatg gcacatacga taaaatctat caaaaatggt ttccaaatga
     2821 aactgaagga aaagtagagt aagggggaga ggcaatgagc gaattgatac aaacttatgg
     2881 accaatcttt gtcgacgggt tcaagatcac attgttttcg agtgtcttag cacttgtgtt
     2941 tagtttgatt atcggaacgt taatggcaat cttccaatta tcaaagaata aagtagtgag
     3001 cgccttagca aaggcatatg tagaattttt tagaaacatt ccattattaa tcatcgtgat
     3061 gtttttttat gttgtcgtac cgatttattg gtttaatcta gatggattcc aagcaggtac
     3121 gattggatta acgatctata catctgcttt tattgctgaa acagtacgtt cagggattca
     3181 aaccgtacca aaaggtcaaa cagaagcagg actatcttct ggttttacct attcagaaat
     3241 catgcgttat attgttttac cgcaagcatt caaaatcgtt atcccgccat taggcaacca
     3301 atttatcaac ctcgtaaaaa actcatctat tttagcaatc gtagctggtt tagatttgat
     3361 gtatcaagga gacttgatcg ctagtgaaac attcaatacc ttcgatacgt atatcatcgt
     3421 tgggttattt tacttagtta tcacgctacc gttatcttac ttaatggttt atcttgagaa
     3481 aaaatgggcg gttcgttcat agaaggaggg gaaatacatg gattttagcg gcgctttttc
     3541 atggatgaat atccgttttt tattggaagg attaaaggtt actgttgaag tttcattgtt
     3601 ttcgatcatt tttagtttct tgatcggtgg tctgacaggt gtgattcgtt ttgcgaatat
     3661 ccctttcttt tccaaaatcc ttggtgtagt gattgatatt atacggaatc ttccattatt
     3721 attgatcatt ttcttcactt actttgcctt acctcaaatc ggcattcaga tgaacatctt
     3781 ctggtccgct gtcgcagcat taacgatttt tgagtcagct atgttgtcgg aaattttccg
     3841 agctggactc aatgctgttc caaaaggaca gatggaagca ggattatcaa cgggactgac
     3901 ttatgtagaa tcgatgcgaa cgatcgtgtt accgcaagca tttaaatcaa tgatcccggc
     3961 aattgtgagc caattgattt cactgatcaa agatacttca ttagcagtaa tcatttcttt
     4021 acctgaactt tctcatcagg cacgtattat ttatggacag aacaccaatt atgtgcttcc
     4081 gatgttcatc atcatgacac ttatgtactt cgtggtatgt tacgcgcttt ctctgctttc
     4141 cggttacttg gaaaagagac ggtacagtta ttaatagatg attcttttag cggttgtggc
     4201 aaactaaagt cacaaccgct tttcctcttt ccattcgaaa aaaagagatt tcgattgttt
     4261 taagcaagta agagcacttg aaaattcacg ctaaaaagta cacaataggg aggatagaat
     4321 ttattgaaaa aaaggatgat acgattgaca gataatcgcc ctatcggatt tattgattca
     4381 ggtgtcggcg gcttgactgt agtaaaagaa gccctgaaac aattaccgaa tgaaaatatt
     4441 ttatttgtag gagacacagc acgctgccca tatggcccta gacccgcgga acaggtaatc
     4501 cagtatactt gggaaatgac ggattatctg gtggagcaag gaatcaagat gctggtgatc
     4561 gcctgcaata ccgcaactgc ggtggcttta gaagaaatca aagctgctct ttctattcca
     4621 gtcatcggtg tgatccttcc cggtactaga gcggcagtaa aaaaaacaca aaataaacaa
     4681 gttggcatta tcggtacgat tggtacggta aaaagtcaag cttatgaaaa agcactgaaa
     4741 gagaaagtac cagaattgac tgtgacaagt cttgcttgtc ccaaatttgt ttcagttgtc
     4801 gaaagtaatg aataccattc atcggtggcg aaaaaaattg tggcagaaac attagctcct
     4861 ttaaccacta aaaaaatcga tacattgatt ttgggatgca cccattatcc attattacgc
     4921 cccatcattc aaaatgtaat gggagaaaat gttcaactga tcgattctgg agcagaaaca
     4981 gtaggtgaag tatctatgct gttagattat ttcaatttga gcaattcacc gcaaaatggt
     5041 cggacattat gccagtttta tacaactggc tctgccaaac ttttcgagga aatagctgaa
     5101 gactggcttg gaatcggaca cttaaatgta gaacatatcg aattgggagg aaaataagga
     5161 tgcgtcatga cgggagaaaa gcccaagagc ttcgcaaact ggagcttcaa acaaatgttt
     5221 tcaaatatcc agaaggatcg gtagtgatcc gttttggtga tacaacagtt atttgttctg
     5281 caacaataga aaattctgtt cccccttttt tgagagaaac aggaacagga tgggtgacag
     5341 cagaatatag tatgctgcct cgagcaacga gtacgagaaa tcgtagagaa agcagcaaag
     5401 ggaaactttc tggtagaaca atggaaatcc agcgtcttat tggtcgttcc ttgcgtgcag
     5461 tagtagactt ggaaaaatta ggagaacgta gtatcatcgt agactgcgat gtgatccaag
     5521 cggatggcgg tactagaaca gcaagtatca ctggggcatt tgtggcattg aaattagcca
     5581 ttgaaaaact tttaagagaa aaagaattgt cagaagatcc aataaaagaa catcttgctg
     5641 cagttagcgt aggaatctta ccagatggga cttgcgtcac agatttggat taccaagaag
     5701 attccgcagc acttgtagac atgaatcttg taatgacaga atctggaaaa ttcgtggaga
     5761 ttcaaggaac tggagaagaa gcaacgtttg atggtgaaca gttgaatgaa atgctctttt
     5821 ttggaaaaaa cgcgattgaa gatttgatca aagagcaaaa acatgctttg ctaacagagt
     5881 ttgctcaaaa tgatgagcgg atagaagaaa caaaaacaat catcattgcg acaagaaatc
     5941 caggaaaagc agaagagttt cgaaatatgt tcaaagaagc gggatatcat gtaaaaacat
     6001 tacttgacta tcctgaattg ccagatgtgg aagaaactgg cagcacattt gaagaaaatg
     6061 cccgattaaa agcagaaacg attgcacaat tgcttgatca gccagtctta gcagatgatt
     6121 caggtttgaa agtggatgct ttaggcggta tgccaggaat ctattctgca cgttttgcag
     6181 gggaacaaaa aagtgatgcg gggaataacg ccaaattatt atatgaattg acagatgtgc
     6241 cggatgaaaa aagaacagca caattccatt gtacgttagt attcgcggca cccaaaaaag
     6301 acagccttgt agtagaagcg gaatggcccg gtcgagtagc ccgtatacca tctggcgaaa
     6361 atggctttgg gtatgatcct ttatttatcc cagaaggtaa gaaacaaaca gcagcagaat
     6421 tatcgagcga agaaaaaaac aagatcagtc atcgggctca agcaatgaaa aaattgagtg
     6481 ccgagtggaa acaatggctg gaaggagaga gatagatgcg gtatttagta gtaagtgata
     6541 atcatggaga cagagatatc ctcgttgact tagtagatcg ttatcgttct gaagtggata
     6601 tctttttcca ttgtggtgat tcggaattag aagcttctga cccattatgg gatacattcc
     6661 aagtggttca aggtaattgt gattatggac caggattcga acagaaaaaa gtgatccaaa
     6721 ctggtcagga tacagtattc atgactcacg gtcatttatc gaatgtccga tttggtttga
     6781 cacagttagc aatcgaagct cgagctgcaa ctgccgatat ggtgtttttt ggtcataccc
     6841 atcaaatagg ctgtgagatg gatcagaaaa tcctgttttt gaatcctggt agcatttctc
     6901 agcctagagg cccgatccaa atcccatcat atgctcttat cgaaagttta gatgaccaaa
     6961 tttctgttca atactataac cgtgcccatc aggcagttga agagttggcc ttttcttttt
     7021 cgagagagcg ctgaataaaa aaactctaat ttttaataaa aataagcttt attttatgaa
     7081 ttttgcatcc ggtttcggta aaatagtagt gttgaatgaa atagaaatgg aggccatcag
     7141 atgattggac ctatagtaag agaaatgctg ctggaaaatc aggaaacgtt tttgattcct
     7201 gcagaaaatg tggcaaatgt tatgtatcat catccattgt cccatggttt acttgtgtta
     7261 tcgaaggtcg gttattccaa aattcctgta ttaggaaaag atgatcactt tgtaggacta
     7321 gtaagtttat cagatgtggt caataaaatg attgacttgc aaacaatcag catggacccg
     7381 ttagaaggac taacggttgc tgatgtgaca gaaacagatg ttccgacaat tgatgaaaat
     7441 tgggaactag aagaagtact ccatttgtta gtcgattcgc cttttttacc ggttgtcaca
     7501 gaagatcgga ttttcaaagg aatcattaca agaaaagagc tgcttaaagc cgtaaacttc
     7561 atggtgcatg aattagaacg tcgtaatata ttgtctccga aaatcgaaga attaaaagaa
     7621 caaatcgata tcgtgagcta aagaacgaga aactaaaaga taatcaaaaa ataagtagaa
     7681 aaaacagcgt accagttttg actttatctt gaaaaagagg ctgggacaaa agcgtttaac
     7741 tccaagaaat aagaaggaat tcacgaaaat tgcttttcaa atttttgtga atttcagctt
     7801 atttccgaag gagttgcttc tgcttccgcc gtttatacgt gtttagagcg tgggacaaaa
     7861 gtgttcttta cttttgtccc acgctctttt tagtgagatt cgttgcatcg tttgtccaaa
     7921 ttattttccg acagcaattg gactgttcgg aatcgtgaaa ccagaagctg tcaattcttt
     7981 gacataggag ctcaagaact cttcttttaa ggcatattgt tttccgttca atgcgtagca
     8041 gaccgtacga atcgcaaaat tgctgtttcc aagatccact aatccaaaga tagaaggttc
     8101 agtttggagc tcttcttggt atttttcagc taatgtacga tttactcgat caatgatctc
     8161 atagattttg tcatatcctt cttcaggaac aatccgaata tctaaaagta cttgcatatt
     8221 tgcacgagag agattgctga tcgtggtgat gtttcgattc gggatgaaat ggacagtacc
     8281 atccgttgct ttcagctgaa gggtacggat accaacagat acgacggttc cttcaatcgt
     8341 taagtttgct agcttgatgt agtccccaac atccatctgt tgttccatga taataaaaaa
     8401 tccggtaata acatcactca tgaacccttg ggcaccaaga ccgattgcca cacctgcaat
     8461 tccggcacca gccaaaagtg atccgatcgg cacaccgata gcagataaaa ttgcatagat
     8521 aaaaaagaaa ccaagggtat aatgaaaaat agtatttaaa agactatgta aagtctttaa
     8581 gcggctctcg tttagaatgg cttttttaga atactgatta aaagacttat caatcagata
     8641 ttttcccaca cggtgaagaa tccaaaaaag gacgatcaaa aaaatcagat ataaactttt
     8701 ttggataaag gcagccaaaa tggcgtccca atcaatcccg tcccaaaacc gctgaaacgc
     8761 atttactttg ctgacagctt gatctgtcaa tgtctcgcca gaagagtctg tcgtaccggc
     8821 agttgctaat aatgaaaaca taaaatcctc ttttctaaaa tttgattctt tctgtattgt
     8881 accaagaagt tttcaaaaaa ggaaatagca aaaataacta taatgaagga aaaaagctga
     8941 aaataaaatg acaaataata tggataatga taaaatgtgg agaaaataac gaaggtggta
     9001 agtatatgca aatcgattgg aacaatctag gtttttctta tatcaaaact ccttggcgtt
     9061 ttattgccaa atggaaagac ggacaatggg aagaaggaga attgacagaa gataattacc
     9121 tgacgattca tgaaggctct ccagcgcttc attatggtca gcaatgtttt gaaggtctaa
     9181 aagcttatcg tcgaaaagac ggcaaggtca atctctttcg acctgaacaa aatagtcgac
     9241 ggatgaatca aagtgctaga cgattgctga tgccaatggt ccctgaaaag atgttcgttg
     9301 atgctgtcaa gcaagtggta aaagcaaatg aagattttgt gccgccctat ggaacaggcg
     9361 ctacattata cttgcgccct ttactgattg gggtcggtga aaacattggt gtccatccag
     9421 ctccagaata tttatttgtc gtcttctgta cgccagtagg agcgtatttc aaaggtggac
     9481 taaaaccaac gaattttatt gtatctgatt acgatcgtgc tgctcctaag gggactggtg
     9541 cagcaaaagt cggcggaaat tacgcagcga gtttacttcc aggaacagaa gcaaaagaac
     9601 tggattactc agattgtgtt tatcttgatc cagccacaca tacgaaaatc gaagaagtag
     9661 gtgcagcaaa tttctttgga attacaaaag acggaaaatt catcactccg caatcgccct
     9721 ctatcttacc aagtatcacg aaatattcct tgttgcagtt agctgaagaa cgactaggac
     9781 tgcaagcaat tgaaggagat attttcattg atgatctaga tcaatttgca gaagctggtg
     9841 catgtggtac agcggctgtt atttctccaa tcggtgggat ttatcacaat aacaatcttc
     9901 atgtatttta tagtgaaacg gaagtaggac cagtaacaaa acggttgtat gatgaattga
     9961 caggtattca atttggagac atagaagcac cagaaggctg gattgaagtc gtggaataat
    10021 ttcaaagtaa tgagttgaaa aaaacgtaaa aagaaaaaat caggaagaga ctttaaaaag
    10081 ttttttcctg atttttatat gttttacttt aaagaatgca acaaaagttt atgaaagatg
    10141 gacacctttg tcaacgtaga taatatcacc gatgattccg ctggaaagtg ggctgattaa
    10201 gaaagcacaa gcattaccga cttcttcgat cgtcacacct tgctgatcag gcgtacgaga
    10261 ttcagataac tggatcagtt tttgatagtc tttaacacct gtgacagcta atgttttgat
    10321 tgccccagct gagattccat tgacccgaat tcctttaggc gagaactcag ctgccaaata
    10381 acggatagca gcttcaagag aagctttcgc aatacccatc atgttataat tcgggattgc
    10441 gcgttctgaa cctagataag tcatgctaac gatcccgctg tttggtgcaa gaaacggttg
    10501 tgcgtatttt gatacagcaa ttaaagagta gctgctgata tcttgagcta attgatagcc
    10561 gtctctggaa atatcagaca catttccgga caattcttct ttgttggcgt aagcaactgc
    10621 atggacaagg ccgtggatct ccccagcata ttcaccgatg gcattcattg ctttttcgat
    10681 gctttcgtcg ctagaaacat cacattctac agtgaatgct tcttcgccga ccaatttgac
    10741 taatgatttt ttcattcgtt cattttggta agtatagata atttctgccc cttgtttcaa
    10801 cattgcttca gcacaacccc aagcaatgct ttttttgtta gcgacgccca taatgacgat
    10861 tttttttcct tctagaaatg acataatgac tctcctttgt ttctgataaa aatttgatag
    10921 tcgtaaaaaa atagagaata atagctaaaa taacttcttg atttcttaat tattagtcaa
    10981 aatgttttga ttgtcaaact attttttctt aaattaaaaa aagattgcta aatatttagg
    11041 aatatgatac tttgatagtc aaagtaatga aaatggcaat tgcctgaaag aaggagttta
    11101 attatgtctt acgtattatc tgctactgaa gtaatggaat tgattcctaa tcgttatcct
    11161 atttgttata ttgattatgt agatacttta gaaccaggaa aaaagatcgt tgcgacaaaa
    11221 aatgtaacaa tcaatgaaga ttttttccaa ggtcactttc ctgacaatcc agtgatgccg
    11281 ggtgcgttga ttctagaaac actggcacaa gcaggttcga tacttatcct aaaatcagaa
    11341 gagtttctag gaaaaagagc ttatatcggt gggatcaata aggccaaatt ccgtcaaaaa
    11401 gttgttccag gagatgtgct gaaatgtcat tttgaaatca ccaaaatgaa gggatcagtc
    11461 ggtacagcgt tatctgcagc atatgtagat gataaaaaag tctgtgagtg cgagttcacg
    11521 ttcatcgtca accaaaatgc ttgactataa aacctgatat agcaaaacaa aaggaagctt
    11581 acttgctttt tatgtaaaaa gaagacgcct gaatcctagc atacgttgtc atctatgcag
    11641 gattcagacg ttattttttt atttttgttt tgcttcttgc agtatattga ttttatcgat
    11701 ttttacttct tcttttggtt tgtctgaact atctgtttcg atatttgcaa tagcatccac
    11761 gacatccatt ccttcaatca cttggccgaa gacagtataa tggccatcta gtgaaggata
    11821 accgccgttt ttataagcgt cgatgattgc ttgaggatag tcgtctttta aaagaccatc
    11881 atgcatatca tctgtatttt gaacgataaa gaactggctg ccgttactgt taggatcttg
    11941 tgagcgagcc atagataacg cacctcttat attataaagg tggttgttga tctctgtttc
    12001 aaatccttct ccccaaatgc tttcccctcc agtgccatcg cctttaggat cgccaccttg
    12061 gatcatgaaa tctttgatga cgcgatggaa agtcagtccg ttgtagtaac cgtcttttgc
    12121 atgtgtcata aagttttcaa ccgcttttgg tgcgtgttcg ggaaataatt tgattttgat
    12181 tgtgccttta ttcgtcacca tttcgaccag atcttcattt tcggcgacat ctttcgtcaa
    12241 ttgtggtaat tccaatgcgt tcaaatcgac gctactggca gtcgtgcttt ccgcagtaga
    12301 tgtacttttt gaactttctg tagacgaact agaagaagtc gtgttgtttg cagaacaacc
    12361 agcagcaaac agcaatgctg ctgctaaact aatacttaaa ataactttat ttttcttcat
    12421 aactgttcct ttccaattta ctattttgtt atctttaatg ataacaaaat agagggaaaa
    12481 tacctactta aattattgga atttatcatt tattttaaaa gaaaaagaaa aggtgtagac
    12541 catttacttt gtgtttgcta taatgtaagt ggatacaaaa acgaaaagat gcaggaggaa
    12601 atggtaatat gggaaaatta ggaatctcga tttatccaga acggtcaaca tttgaaaagg
    12661 acaaagcgta cttggattta gctcataagt atgggtataa acgggttttt accagtttgc
    12721 tgcagatcaa tgatgataaa gaaaaagttc tttcagaatt taaagaagta gttgattacg
    12781 cgaatagcct aggcatggaa gtaatggttg atatcaatcc agcgttattt gaacagttgg
    12841 agatttctta cgatgactta tcttttttcc ataagatggg tgcctacggg gtccgcttag
    12901 atatcggatt cacaggagca gaagaagcaa aaatgacgcg caatcctttt ggtatcaaaa
    12961 tcgagatcaa tatgagttcg ggcacgaatt acgttgacaa catcatgagt tattcgccaa
    13021 acacggataa tttattaggt tctcataatt tttatcctca tcgatactct ggtttaggat
    13081 acgaacactt tgttttttgt tcagaaaaat tcagaaaata taatttgaat acgatggcat
    13141 tcgtcaattc gcaatctgct gagtttggcc cttggcctac gcaagatggc ttgtgcacgc
    13201 tggaagacca ccgagatctt gaaattgcga cacaagtgaa gcatttaatc cttacaggat
    13261 tgattgatga tatttctatt ggaaatgcgt acgcaagtga agaagaattg aaagaaatgg
    13321 cagaagcatt taacgcggat tatccaacat tgaaagtaga tacggaagaa ggtattacag
    13381 aaaacgaacg aatctgcttg tttgataacc ttcatagtta tcgaggggat cgctcagaat
    13441 atatccttcg ttcaacgatg actcgtgtat actacaaaga taaagatttc ccgcctcata
    13501 atacgcgaga tatgcatcat ggggatgtac tgattgacaa tgaagggtac ggtcaataca
    13561 aaggagaaac acaaatcgcc ttgaaggata tgaaaaacga cggacgtgtc aatgttgtag
    13621 gaagaatctc cgatgacgaa ttattcctcc ttgacttttt gaaaccatgg tcaagcttta
    13681 aattaattga aaataaaaaa tagataatta gttattgcag aaataatccg ctagaaatag
    13741 ccagttattt ctgctttttt attttgtttt tttatagg
//
LOCUS       DAXQKX010000068        13738 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.070, whole genome shotgun sequence.
ACCESSION   DAXQKX010000068 DAXQKX010000000
VERSION     DAXQKX010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13738
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.070"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(63..1268)
                     /gene="mobT"
                     /locus_tag="ACF3MF_002283"
     CDS             complement(63..1268)
                     /gene="mobT"
                     /locus_tag="ACF3MF_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobT family relaxase"
                     /protein_id="HFE3928226.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            complement(1291..1444)
                     /locus_tag="ACF3MF_002284"
                     /pseudo
     CDS             complement(1291..1444)
                     /locus_tag="ACF3MF_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            complement(1447..2832)
                     /locus_tag="ACF3MF_002285"
     CDS             complement(1447..2832)
                     /locus_tag="ACF3MF_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HFE3928227.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            complement(2861..3247)
                     /locus_tag="ACF3MF_002286"
     CDS             complement(2861..3247)
                     /locus_tag="ACF3MF_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFE3928228.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            complement(3263..3577)
                     /locus_tag="ACF3MF_002287"
     CDS             complement(3263..3577)
                     /locus_tag="ACF3MF_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFE3928229.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            complement(3930..4409)
                     /gene="rlmH"
                     /locus_tag="ACF3MF_002288"
     CDS             complement(3930..4409)
                     /gene="rlmH"
                     /locus_tag="ACF3MF_002288"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HFE3928230.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYGLAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            4837..6126
                     /locus_tag="ACF3MF_002289"
     CDS             4837..6126
                     /locus_tag="ACF3MF_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HFE3928231.1"
                     /translation="MDRKNVTPKMKKNKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVMMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            complement(6165..6770)
                     /gene="ytpR"
                     /locus_tag="ACF3MF_002290"
     CDS             complement(6165..6770)
                     /gene="ytpR"
                     /locus_tag="ACF3MF_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HFE3928232.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVASYGMICSARELHLPNAPEKKGILVLPEDAVVGEVFPK"
     gene            complement(6966..7430)
                     /locus_tag="ACF3MF_002291"
     CDS             complement(6966..7430)
                     /locus_tag="ACF3MF_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFE3928233.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKALEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKQMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYAIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            complement(7452..7772)
                     /locus_tag="ACF3MF_002292"
     CDS             complement(7452..7772)
                     /locus_tag="ACF3MF_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HFE3928234.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VIKG"
     gene            complement(7915..8994)
                     /gene="pepA"
                     /locus_tag="ACF3MF_002293"
     CDS             complement(7915..8994)
                     /gene="pepA"
                     /locus_tag="ACF3MF_002293"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HFE3928235.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            9194..9544
                     /locus_tag="ACF3MF_002294"
     CDS             9194..9544
                     /locus_tag="ACF3MF_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFE3928236.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKTSFLKEGAIEGAWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLDISRKKGAID"
     gene            9729..10682
                     /locus_tag="ACF3MF_002295"
     CDS             9729..10682
                     /locus_tag="ACF3MF_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFE3928237.1"
                     /translation="MESREKIAVLIPCYNEEATISTVIEDFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAAHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVKNTITYLYKTKIRDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMCKDYKPLLFFGIWTIFFFLFGLVMGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYQNKEMK"
     gene            10695..12482
                     /locus_tag="ACF3MF_002296"
     CDS             10695..12482
                     /locus_tag="ACF3MF_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6020 family protein"
                     /protein_id="HFE3928238.1"
                     /translation="MHKKKENLFPTFFATLFASGFAFFTSYGLGTLNPTVIIGLAMVL
                     LLAFKQYGIELFSIKNKVAAIARLFFSAAFALTLSIGRQIQFQYVSANYTKTTIADGS
                     IFYFLVYFSIFVYSFLFLQSIYLSMPKLETFFTAQNTQAFSSRKYFLFFTVFLVLCWL
                     PYLLALYPGVVLPDSLSSVAQSMGDVPISNHHPVLFTLLVKLFVHDLPTDTINHGVFL
                     FSIFQTLITASAISYSLCWLLKRNIHFFPVLISLCYFAFAPVFPIYALNMQKDTLFSI
                     ACFLFSLAVFDFIFQREKPTILNQIYVIILALLTTYLRNNGIYVVTGTGLICGLIILK
                     QKRYQAFFQVVLGYTVIAGLLIHPLMARYAIPTETAEQLGVPLQQISRTIVMDGDLSK
                     KDKAFMNQLLPIKDYEAYSPSLADSIKWHKNFNNEFLNTHKKEFLSLWARNLPSNIKI
                     YTDAYILETFGFWVPGTKNSYGFLDTRVNTNNYGMKQVDLIEHLTGLSGMKKIIDARD
                     FFGSGTLLWLAIGSALLAIFKKKYRYLLLFLPGMLVFATIMIATPVAFSLRYVFVLAL
                     GLPVYILSPFLLDKREKMKTDIGDTHETI"
     gene            12469..13671
                     /locus_tag="ACF3MF_002297"
     CDS             12469..13671
                     /locus_tag="ACF3MF_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928239.1"
                     /translation="MKLFKKIFFAFVLLIASYCVLLTITFFIPQHSIESNAEKSLQMV
                     EKEGMYPSINQGNMLGTRLDNFTDHLMIRKTKADPELNSLENAMSMADYPRYWHGYQL
                     FLRPLLLGMSLGSIRMIYAAILFLLIGLTSYFLTKCSDIYLTTALLISLAIGNAATFF
                     FSMQFSNIWILTLLSVLLFLTKPQLSNTNQQLFLYFFVIGSLANFFDLLTTPVISWGI
                     PVIIIYYVTNKYLMDKRSSLSKQVGSFVFTGIFWGLGYGLTWVAKWILSSIILNKNIV
                     KDAINQILFRTEGNDKYPLHRLEMLKSNIRLMYPKVAILLLLITCLVFLYFAYRKRNS
                     WRPFQLLVLFVLAAVTPYIWYNILANHSQIHYWFTYRTQIITSFAILSAFAFLIPPEK
                     SKDELNYF"
BASE COUNT         3938 a         2689 c         2520 g         4591 t
ORIGIN      
        1 aggttttgtc caaaattcat aaaaatgttc tcctctctat attcaatgaa tttgtatttg
       61 agttattttt ttgttgttat cacgtcctgt tcttttactg actgttgctt caaaatctgc
      121 ttgtgtcggt ctgtcagttt cgcatggtcg agaatgtctt ttacaacctg cgtctggttg
      181 atttcatcaa gtttaatcgc aacctttaag gtcggggcaa cttgatgaga tagccagttc
      241 agcgtccttt ggaaggagta aggctctggt tttgtggtta gttttaatcg ttcacgattg
      301 ttcccaataa accaagccca ttcttcattc agtttccaat cagaacgagg tttggaatcg
      361 tctttatcta caaaacggat ataccgattg ataattttaa aggcggtatg ctctggattg
      421 tcatagacga gtaaatcacg gactgcataa taggcacgct catttttcaa tcgaatctca
      481 aaacggtttt ttacttctgc gtcttcaatg ggaatatcat ttttcttgta ctgctcgtag
      541 tccttttcat agatacagaa ataaacttca ctttgtaatg aaccgatata gagggtgttt
      601 cccatacatt ccttttcctc tttgcgtacc agttcgccac tgcgatagct tttaaaactg
      661 cggaagacgg agatacattc ttcctgttgg cacttttcag tgagtacagg gatatttaaa
      721 atccctgtct tatcgttaat ggcaaggtca aggcgtttca tcacaccgcc agccaccaaa
      781 acgtccataa agaactcata ccagcttctt tgttgtgcca gaagatagct ttcaaattgt
      841 ctgcacccac gacctttcaa ttccaccaga actcctttgt ccagttcatg ggagcaaagg
      901 acgaatatgt cgcctaaagc ataatgctct gaataagaat agaaaccata gtcctcatga
      961 agaaaatagg acagtttcag ttgtaagatg ttttcgacca cctgctgtac gtctgttgtc
     1021 ggaaagcgaa ttcttacata atcaaacagc atttcaaggg gagcgtcggg attgaagcgt
     1081 tccagagctt cccaaaggga ctgctgtaaa tcctctgatg gcttgacttt tcctgtttca
     1141 atatcgctta gatactgcct tgtaatacca gtcgcaacag ctaaacggtt ttgagatagt
     1201 ccataagcca agcgtttttc ttttaaatgc tgtaaccaag tttgttcatt cagtaaaaat
     1261 ccctccaatc aaaaaggcgt atgtcaactt ttaaagccca tttgacatac gctgaaattt
     1321 tgtaaatccc ttgtaaccaa aggattttct aatgtttttt tgactgtttc ctgtcgattt
     1381 gtacccccct gttagatacc gaggggttaa gtgctggcgt ggctattgcc acaccagcca
     1441 gcaagatcag tccacacctg cgacttccgc ttcgcacgtc gcctgcgtgg actgtctgct
     1501 gttggataac tttttaattt cctccaagaa atcatatcct tttggtacaa ggggagtata
     1561 aaactctgat atgacacttg ttcctacatc aacatagcca cgacctttga ttcgctttaa
     1621 gaagaaatcc ttttgtacgt cactgccaaa catcatgcca tagcccattt cagacatacg
     1681 acctaaagcc actctgaaat taaactgatc acggattccg tcgcctaaat attttgcgtc
     1741 tggacgttga caagccagta ttagaaagaa gccagcttga cgacctaaca tgacaatctg
     1801 tttcagctta ttcataactg cggtgttttc ttttgttccc agcatttcca tgaaagcgac
     1861 gtattcatca aagattaaga agtgtgccgg gagacctaag taagcataat ttttgccagt
     1921 cttatagttc ttcatctgct tcatttcctc actacgtttc atcatttctt catagaatgt
     1981 ttcaatgcaa gaaagcaagt cttcttttct atagtagaca tttgccatca cagaacctaa
     2041 gtccgcaagg tcagcatttt tcgggtcaag aatatacagt tttgaatctg tatgaagcaa
     2101 ggcttcaatc agtgtcagta taaagtaagt tttaccgcca cctgtaccac cagcaatcaa
     2161 catatgaggg agcttatcat attcccacca tacgtttttc attaagcgaa gtttaccatc
     2221 tttagcttct acttcatcaa tagaaatacg actggctatg gtgtcataga gcaaagtata
     2281 ttccacatag gaatccttta actctttatc cgtcagctca cagtacaagc cactctctaa
     2341 tttcttttcc aagtgtaaga gttggtcttg atattttccc agcgtgattt ccacccgtat
     2401 ctgtatcaag ccatttttaa gtcgataata cattttaggg aagtaggtta tcttttcctt
     2461 tgtacgacca gcactatctt taaagaaacc ctctgttttg acctgttcag attcatacca
     2521 cttgttttca agtatcatct ttgccagttt ttgacggtgg taaagttgtt taaccgtatc
     2581 atagcgaacc cgtttgaata caaacgctac cagcaagcag ataagaattg cgacactgaa
     2641 actgataatt aaatagggaa tgtcaatctt atctgcttgt gataggttaa aatcctgcca
     2701 gttgatctgc tggattgtct tcacatgaaa cagtccgaca accagcagga aaacaggcag
     2761 gagtgacgct atcgtaaaat gaaagactaa atctttacca gatgggcgaa tccttttacc
     2821 acgctgtttc atgcgaaaaa gtctcctttc tacctagcga ctatttgtct tgtgtcggtt
     2881 ctttctttgc ttgtggttga gctttgaatg aactagaatc ctttgtcagc acaatatcgt
     2941 ctgccttgat ataccagtca acatctgctc cttgataggt ggcagtagca acggtgtccg
     3001 caatgggatt gataagttcc acccgtgcgt tataatcaaa ctctttcaaa ggcacgctgg
     3061 caggaatact tacttgaatc atgcgtcctt gtcctttgga ttttaagtca taggtacgtt
     3121 ccttgatttc atctgaaacc gacccgtctt cattttggat tctcacttca cgacgtagag
     3181 cagagaattt caattctcca aaagtcgtgt ctttatctaa tacaatgcca tttgctaatc
     3241 tcatcatttt tcctctcttt ctttattctt ttatcatgtc gtcagcatgt aaaaggtaat
     3301 ttgtaaaacc acgagtgccg attttgtagc cctctgcggt aatacgtgga ttgactaact
     3361 tcacacgttc ctcaaagccg aaatgttttt cgccagcttc agcaggaagc accaccacaa
     3421 tatcatctgc tctttgaaca tcagaataga gattatagct tcttgataag acagttagcc
     3481 gtccgttgat tcttcgctga acgactttat cctcgccagc aaattctaaa ttgccgaatg
     3541 ttttttccat gttgggaatc acaaatttaa gttccatatt tttacctatc ctttcttttt
     3601 tattggctga atgaatgttt gatggtctta aagagtgggg aacgaccttt tgattcttga
     3661 ttttttgttt tcataagttc acttcctttc aaaatcgggt aaaaaaatag acacctcatt
     3721 ttttgaagtg tctacctatt aaatattcaa attttattgg aagtatcttt atatcttcac
     3781 ttttcaagga taaatcgtcg tatcaaagct cattcataag tagtaaatta gtagtaaatt
     3841 gagtggtttt gaccttgata aagtgtgata agtccagttt ttatgcggat aactagattt
     3901 ttatgctatt tttctcttaa aaaatatcat tatttgtggt atggagcccc cgcgttgatc
     3961 cggaaggcac ggtagatttg ctcgacgagg atcaggcgca tcaattgatg tggatacgtc
     4021 attttgccaa aagagatctg agcattgctt cttttcatga cggcttcgct gagtcctaaa
     4081 gaaccgccga taacaaaaac aaggtggctt tttccttgga tacctaattg gtcgatttgt
     4141 ttagcaaaag attcgcttgt gggatttttc ccttcaattg ctaagccata gacgtattct
     4201 tgttctttga ttttcgctaa gatccgttct ccttcttttt cttttacttg tctcatttgc
     4261 gcttcgctta aattctccgg ggctttttcg tcaggaactt cgatcaattc gattttcgca
     4321 taggcattca gccgtttgac atactcattg ataccttgga tcaagtattt ttcttttaat
     4381 tttcctactg aaataatttt gatattcatg ttttctctcc tttgatcttc acgctcactt
     4441 tgtttattat aatcaatttt ttcgtctata tgtttatttt gactattttt gttaaaaaga
     4501 tttccccaac agttatgcac aacatccaca ggtttatcca cagaaaacag cgttgtttta
     4561 ccttatttca tcacattcat taggcaaaca tacgttttat aagaatttat ccactttata
     4621 cacaggctgt ggatatgttt tatcccttat ttttccaatc ctatccgcgt agttttacac
     4681 aatatctgtg gaaaaagaaa atcaaatatt ttcatctgaa aacaatgatt tttcctaaag
     4741 tttttcataa aaagttcaaa gtctcaaagt agactaaagt caacaaataa gactatacta
     4801 acagtagata aatgaatgta attggaggag gaacacatgg atagaaaaaa tgtgacacca
     4861 aagatgaaaa aaaataaaaa taatagcctc tggcgtaagt tgggtctggg gcttgttgga
     4921 gggatcgttg gaggactact gacagctggc attttttatg cagcgatggg cactggcaac
     4981 aatagttcta ctgctacaag cggcaatcaa aattctgccg gtgaaacagt tgtggaaaat
     5041 gtcaaagtca atgtagattc tgatatcacc aaagcggtag ataaagttca agacgctgtc
     5101 gtttctgtta tcaacttaca aagtcaaaac caatcaagcg gttttggcgg attattcggg
     5161 cagcaagaag aaagtagcag ctcagatgat agtaatttgg aagcttatag tgaaggaagc
     5221 ggcgtaatct acaaaaaaga cgggaatact gcttatgtag tcacaaacaa tcacgtagta
     5281 gatggacagc aaggtttgga agtcatgatg aaagacggta cgaaggtaaa agctgaatta
     5341 gttggaacag atgcctattc agatttagcg gtgttgaaga tcaattcaga caaagtcgaa
     5401 acggttgcct cttttgggga ctcaagtgct ttgaaggttg gtgaacctgc gattgcgatt
     5461 ggttccccat taggatctga atatgcgaat tctgtcactt caggaatcat ttcttccttg
     5521 aaccgacaag taacaagtac gaatgaatcg aacgaaacag tcaatatcaa tgcgatccaa
     5581 acagatgcag cgatcaaccc gggaaattct ggtggtcctt tagtgaatat cgaaggacaa
     5641 gttatcggta tcaactcaag taagatcgca agtacttctg aatcgacttc taatgtaagc
     5701 gtagaaggaa tgggatttgc catcccaagt aacgatgtag tgaatatcat caaccaactg
     5761 gaaaaagacg gaaaagtgac acgtccagct ctaggtatca caatggtcga cttatctgcc
     5821 gtttctactc agcaacaaga acaaatcttg aagattcctt catctgtaac taacggtgtc
     5881 atcgtgacaa atgtccaaac agctacaccg gcagaaaaag ctgggttgaa acaatacgac
     5941 gtcattacta agatcgatga caaagaagtt tcttctggtg tagaacttca atctgctttg
     6001 tataagaaaa aagtgggaga ttctgtcaaa atcacttact atgaaggctc gaaagaaaaa
     6061 acaactactg ttgaattgac gatcgatcaa tcggcattaa aacaaaatca aaatagtgaa
     6121 aattaataaa aaagaggttg tgacaaagac ttgtcacaac ctctttattt tggaaatact
     6181 tctccgacta cggcatcctc aggcaatact aagattcctt ttttttctgg agcatttggc
     6241 aaatgcaatt cacgagcaga acaaatcatt ccatagctgg ctacccctcg caaagttcct
     6301 ggccagatca tcattccatc tggcatcatg gctcctggtt ttgcaacgac aactttttgt
     6361 ccagcttcga tatttggtgc accgcaaaca atttgcaata ctgtcccatt gtccacttct
     6421 gtctcagtaa tcgataaatg gtcagagtca ggatgcggga cgcatgtttt tacatacccg
     6481 acaacgatct tcggttcatg atcagcttca agctgttctt cgaatcctgc ttctttaatc
     6541 aatcgattca atttcgctaa ttcttcatct gttaagctta cttggccgtt cccttcaatt
     6601 gttagatgat cggagatatg gaaaaagttc caagcaacaa cttgaccttg ttcatctttg
     6661 atccgagcaa cattccattt acgttcgaca gtgttttctg ttcctttatc gtcggctatg
     6721 ataaccatca aagtgtctcc gacgtgtgct ttgttataag caaaaatcat gttctttcct
     6781 ccattatcct ttgctgagat ttatcttaac aaaaaattgc attcactgca tgagattttt
     6841 ttcatgcttt atttccgaag aagcttcttc tggaacacca tttattcgta acaagggact
     6901 gtgacaagac ttttgtcaca gtccctttac tgtttgatta aaaaggttat acaagttcca
     6961 cttgcttaat tactcggctg ttcttcttcg tcagaaacga tcaagacatc acaaggtgaa
     7021 tgacgtatga cgtagctggc tacacttcct gtcataaagc gttcgactgc atttagtcca
     7081 gactgcccaa ccatgattag atcgattgca tatttttttg gcaatttgac tgccatggat
     7141 tcacgaacag agccgtatgc aataattcct tctatatttg tgtaatcaac agattttcca
     7201 tattctttac attcttcgat catttgcttg gctgtttcag tttgctgatc gactagattt
     7261 tgatcaatag gagcatagcc cataaaatta taaaattgct gatcgattac gtttgctaca
     7321 tatactttcc cattattacg gcgagccact tctaacgctt ttttgaaagc agcaagtgct
     7381 tgttcactac cgtcaatacc tactaaaatg ttcttatatt cttgattcat cttgacccct
     7441 cctaacagat gtcagccttt tattacactt tctaggaacg attcgatttc ctgttttgtt
     7501 ttacgatctt tattcactag acgacctaat tcttttccgt cttggatcac gacaaaactt
     7561 gggataccaa aaatgttcca ttcagcggct acatctatgt acttgtcacg gtctacttca
     7621 ataaattgcc aatcagaaaa gtcattttcg atttcaggca tttgcggttt gataaaacgg
     7681 cagtctccgc accagccggc agtaaagaaa aatacacttt ttccagtttc tacgtagcct
     7741 gctaattctt ctaaactatt tgggataatc attctttttc ctctactttc tgtttatgta
     7801 tttttcaatt aaattataca cctttctttc gaactaacaa acattgatcc tctttttata
     7861 aaaaaaatct gacaaaaggt tgcttttgcc agattttata gtttcactat cgcgttattt
     7921 cccgtatacg atcgtgttca ctgttgattt atctaaacct ttcaatgttt gaatcaacat
     7981 ttctcgtgca gcttcaaaat cgcgaatact gaacatcgtt tgatgcgtat ggatataacg
     8041 tcccactacg ccaatcactg tacttgggat tccttcattt tgtgtatgag cagcacctgc
     8101 atctgtaccg ccttttgaaa caaagtattg ataagggatg ttgtttgttt cagcgatatc
     8161 tagcaagtac tcacgcaaac gaggaagcat gatcaaacct ggatcttgga tacgcatcaa
     8221 tgtaccttct cctaaatgtc cgaatgtgcc atttttcgtc actgtgtcat ctgctgcaga
     8281 gcagtctact gcaaagaaca gatctggctt gaatttattg acagaagctt tagaaccacg
     8341 caagcctact tcttcttgga cattcgcgcc tgcaatcaat gtatgaccta atgtttcatt
     8401 ttgtaacgct tctaaagctt ctaataccat tgtacagcca tagcggttgt cccacgattt
     8461 gctgatgata ttcttcccgt tggctgtttt gatcgtttca gcgtaaggaa cgattgtgtc
     8521 tcctggaaga acaccgtaac tcattgcctc ttctcttgat tcaaacccag catcgaacaa
     8581 aatatctgtt acttctactg atttttgtcc gcttgttcct cgtaataaat gtgggggaac
     8641 ggaagaagaa atacatggat aattcttacc agtagaggtt ttaagtgtaa aacgttgagc
     8701 agaaacaacg taagggttcc atccgcctag aggtacgact ttaaaaagcc cgttttcttg
     8761 gatttgtgtc agcatgaatc cgacttcatc catatgtgct gcgaccatta cacgaggtgc
     8821 atccgcttct tcatggtggc gcagcccaaa aatgccgccc aaaccatcta actgtaactc
     8881 atctaccagc ggttccatat gactttccat ataggcgcga acgtcttgtt caaaaccgct
     8941 tgttccttgt aattctgtta actctttgat tcgttgaaat gttttttctt ccatatgcta
     9001 ttcgtctaaa tttcagacta aactcctctc agacttatat tgatctgcgg ataaaatatg
     9061 attttttctg cagaccgatc gtatttatta tagcttattt tttctggtag cggttattta
     9121 tttcaaagaa aatatgagag tgtggtaaaa taaacacaaa gagtagcaag tgagaagaag
     9181 gaggtatatc cacatgtatg aagaaagcga attaagctat tttaaaggcg ggttagccgt
     9241 tgggatcggt ctaggattat tgagtggggt agcttcaacg atttggtatc atcgcaaaaa
     9301 agtgttatca gcagaccaag tgcttgaaaa tatcaaaaca tcttttttaa aagaaggcgc
     9361 aatcgaaggt gcttggatct cttttgaaaa agaacctatt cggaaattcg ccgttcggtc
     9421 gagtgcttat cggggtgggc tttcccggat agaagatggc gaaactgttt attatgaatt
     9481 tttagcagat gctcatacag gaaccgtatt agacatttca agaaaaaagg gcgcaataga
     9541 ttaatacgtc aaaaaaatga aataacgaat acgcacccac tatctaaaag agaggtatcc
     9601 tatccttctt ttatagtggg tgatttttat aaaaataggg ctatttcctc ttggaatagc
     9661 tagtatttgt agttattata cggtattctt gaaataagat tagttttatt atataaggag
     9721 agtgacaaat ggaatcacgt gaaaaaattg ccgtgctcat tccttgttat aacgaagagg
     9781 cgacaatttc aactgttatt gaagatttta aaagggaatt accagaagca gatatttatg
     9841 tctatgataa taattcgacc gatcgaacat acgaattggc cgttcaaggc ggagcaatcg
     9901 taaagaaaga accacgtcaa ggaaaaggga atgtaatccg tcaaatgttt tttgatattg
     9961 atgccgatta ttatttgatg gtagatggtg atgatactta tcctgcagaa gctgcacatg
    10021 gtttgcttga gaaattacgt tctggcgaag cagatatggt cattggcgat cgtctatcaa
    10081 atggaaccta ttttgatgaa aataagcgtc ctttccatga ttttgggaat aatctggtta
    10141 aaaatacaat tacttactta tataaaacaa aaattcgcga tgtcatgacc ggctatcgag
    10201 gattcaatcg aatttttgtc aaaagcttcc ctattatgag ttctggtttt caaatcgaaa
    10261 cagaattgac gattcatgct ttagataaaa aattcaagtt cgttgagatt ccaatcgatt
    10321 atcgcgatcg tcctgaaggt agcgaatcaa aattgaatac attctctgac ggattcaaag
    10381 tgatcatgat gatcatcaaa atgtgcaaag attataaacc tttgcttttc tttgggatct
    10441 ggaccatctt cttcttttta tttggattgg tcatggggat tcctgtgatt cgtgaatata
    10501 tgctgacaag ctttattaca cgcatccctt ctgcgatttt aagtactgga ttgatgactt
    10561 tagcccttct ttcattagta acagggttga ttttggatac ggtcgtcaca aatgccaaga
    10621 aagaatatga attgaattta taccatgtct accacgaata tcaaaataaa gaaatgaagt
    10681 aggaggcctt ttttatgcat aagaaaaagg agaatctatt tcctactttt tttgcaactt
    10741 tatttgcgtc aggttttgct ttttttactt cttatggtct aggaactttg aatccaacag
    10801 taatcattgg tttagccatg gttttgctac ttgcttttaa gcaatatgga atagagttgt
    10861 tttcaataaa aaacaaagtt gcagctattg cccgattgtt tttttctgca gcttttgctc
    10921 ttacactttc tattggcaga cagatacaat ttcagtatgt ctcagcaaac tatacaaaga
    10981 caacgattgc tgatggaagt attttttact ttcttgttta tttctccatt tttgtgtatt
    11041 cttttttatt tttacaatcg atttatttat caatgccaaa actggaaaca ttttttactg
    11101 ctcaaaacac acaggctttc tcttcaagaa aatatttttt attctttact gtctttttag
    11161 ttctgtgttg gcttccttat ctgttggcat tgtatcctgg agtggttttg cctgattcgt
    11221 taagttcggt cgcccaatct atgggtgatg ttcctataag caatcatcat ccagtcttat
    11281 tcaccttact ggtcaagcta tttgttcatg atttaccaac tgatacgatc aatcacggtg
    11341 tatttttatt ttcgattttt caaacattga taacagcttc agcgataagt tattctcttt
    11401 gctggctgtt aaaaagaaac atccattttt ttccggtact cattagttta tgctattttg
    11461 catttgcacc ggtttttcca atctacgcct tgaacatgca aaaagatact ttgttctcta
    11521 tcgcttgctt tttattttcc ttagcggttt ttgactttat ttttcaacga gaaaagccaa
    11581 cgattctcaa tcagatttac gtaatcatcc ttgctttact gaccacctat ctaagaaata
    11641 atgggattta tgtagtaacc ggcacaggtt tgatttgcgg cttgattatt ttgaaacaaa
    11701 aaaggtatca agcattcttt caagtggtgc tgggttatac agtgattgct ggactactca
    11761 tccacccgtt gatggctcgt tatgctattc ctacagaaac tgctgaacaa ttaggtgttc
    11821 ctttgcagca aatttctaga actattgtta tggatggtga cttgtctaag aaagataaag
    11881 cattcatgaa tcagctactc ccgataaaag attatgaagc gtattctcct agtcttgcag
    11941 actcaatcaa gtggcataaa aattttaaca atgagttttt gaatacacat aaaaaagaat
    12001 ttctatcact atgggcaaga aatttaccaa gtaatataaa aatctataca gatgcttata
    12061 ttttagaaac gttcgggttc tgggtacctg gtacaaaaaa tagttacggc tttttagata
    12121 ctcgtgtaaa cacgaataat tatggtatga agcaagtaga tttgattgaa catcttactg
    12181 gattgtcagg aatgaaaaaa atcatcgatg ctcgtgattt ctttggttcc ggcacattac
    12241 tgtggttagc tatcggcagt gcacttttag caatctttaa gaaaaaatat cggtatttac
    12301 tcctttttct tcccggtatg cttgtttttg ctactattat gattgctact cctgtggctt
    12361 ttagtttacg gtatgtgttt gttttagcat taggtctacc tgtttatatc ctctctcctt
    12421 ttttactaga taaaagagaa aaaatgaaaa cagatatagg agatactcat gaaactattt
    12481 aaaaagatat tttttgcttt tgttctcttg atcgctagct attgcgtact actgacaatt
    12541 acttttttca ttccgcagca ctctattgaa tcgaatgcag aaaaatctct acagatggtt
    12601 gaaaaagaag gaatgtatcc ttctatcaat caaggaaata tgctaggcac tcggttagat
    12661 aattttactg atcatttgat gatacgaaaa acaaaagcag atcctgaatt gaactccttg
    12721 gagaacgcga tgtctatggc ggattatccc cgttattggc atggttatca gcttttttta
    12781 cgacctttac tgctagggat gagtttgggg agtattcgaa tgatttacgc agccattctt
    12841 tttctgctga ttggattgac gagctacttt ttaaccaagt gtagcgacat ctatttaacg
    12901 acagccttgt tgatttcgct tgctatagga aatgctgcaa cctttttctt cagtatgcaa
    12961 ttttcaaata tttggatttt gactttattg tctgtattac tatttttaac aaaaccacaa
    13021 ctctccaaca ccaaccaaca attattcttg tatttctttg tcattggttc tttagctaac
    13081 ttttttgact tgttgacaac accggtcatc tcttggggga tacctgtgat cattatttat
    13141 tatgtaacaa ataagtattt aatggataaa cgcagttcat tgagcaaaca agtaggcagt
    13201 tttgttttta ccggtatctt ttggggatta ggctatggtt tgacatgggt ggctaaatgg
    13261 atcctatcat cgatcatatt gaacaaaaac attgtaaaag atgcaatcaa ccaaatcctc
    13321 tttcgaacgg aaggaaacga caaatacccg ttgcatcgat tagagatgct gaaaagcaat
    13381 attagattga tgtatccaaa agtagcaata ttattgctat tgattacttg tcttgttttt
    13441 ctctattttg cttatcgtaa acgaaatagc tggcgtccgt tccaacttct agttttgttt
    13501 gttttagctg ctgtaacgcc gtatatttgg tacaatattt tagctaatca ctcacagatt
    13561 cattattggt ttacgtatcg tacgcaaatc atcacaagtt ttgctatact tagtgctttc
    13621 gcctttttga tccctcctga gaaatcaaaa gacgaactaa attactttta agaataccga
    13681 tgtactaatt catttttaaa cataaaaact ccagctgtca gagatagccg gagttttt
//
LOCUS       DAXQKX010000069        13146 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.071, whole genome shotgun sequence.
ACCESSION   DAXQKX010000069 DAXQKX010000000
VERSION     DAXQKX010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13146
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.071"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(77..149)
                     /locus_tag="ACF3MF_002298"
     tRNA            complement(77..149)
                     /locus_tag="ACF3MF_002298"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Lys,seq:ctt)
     gene            530..1099
                     /locus_tag="ACF3MF_002299"
     CDS             530..1099
                     /locus_tag="ACF3MF_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HFE3928240.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1086..1946
                     /locus_tag="ACF3MF_002300"
     CDS             1086..1946
                     /locus_tag="ACF3MF_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFE3928241.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2136..2840
                     /gene="yycF"
                     /locus_tag="ACF3MF_002301"
     CDS             2136..2840
                     /gene="yycF"
                     /locus_tag="ACF3MF_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HFE3928242.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2845..4680
                     /gene="walK"
                     /locus_tag="ACF3MF_002302"
     CDS             2845..4680
                     /gene="walK"
                     /locus_tag="ACF3MF_002302"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HFE3928243.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4677..5993
                     /gene="yycH"
                     /locus_tag="ACF3MF_002303"
     CDS             4677..5993
                     /gene="yycH"
                     /locus_tag="ACF3MF_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system activity regulator YycH"
                     /protein_id="HFE3928244.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5994..6863
                     /locus_tag="ACF3MF_002304"
     CDS             5994..6863
                     /locus_tag="ACF3MF_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HFE3928245.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6918..7727
                     /locus_tag="ACF3MF_002305"
     CDS             6918..7727
                     /locus_tag="ACF3MF_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFE3928246.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7830..8459)
                     /locus_tag="ACF3MF_002306"
     CDS             complement(7830..8459)
                     /locus_tag="ACF3MF_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFE3928247.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8629..9921
                     /locus_tag="ACF3MF_002307"
     CDS             8629..9921
                     /locus_tag="ACF3MF_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFE3928248.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9997..10659)
                     /locus_tag="ACF3MF_002308"
     CDS             complement(9997..10659)
                     /locus_tag="ACF3MF_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFE3928249.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10884..11168
                     /gene="groES"
                     /locus_tag="ACF3MF_002309"
     CDS             10884..11168
                     /gene="groES"
                     /locus_tag="ACF3MF_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HFE3928250.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11219..12844
                     /gene="groL"
                     /locus_tag="ACF3MF_002310"
     CDS             11219..12844
                     /gene="groL"
                     /locus_tag="ACF3MF_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HFE3928251.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4369 a         2265 c         2833 g         3679 t
ORIGIN      
        1 taaaaaaaga acagcgtaaa tgttttcgaa atgctttcgc accaacattt acctgttccg
       61 tgggtttggc acccaatggg ccgtgagggg ctcgaacccg cgacccgctg attaagagtc
      121 agctgctcta ccaactgagc taacggcccg tacaaaaagt acttaataat agtagcacta
      181 agaattttaa aatgcaagac tacatttaaa gaaaatcaga aaaatcttta cttccttata
      241 ggaaatcatt catagattat tcacatttgc tcgctattat ataagcatac caacaaacaa
      301 agttcttgca agagaacaaa ccctaacact tttttcattt tttactcctt tcccgccgtc
      361 tccccggcgg gtctcctgtt cttaacgata aaagacaaga aggcttagcc ttcttgtttt
      421 ttgttttcat ggaatcccgc taatcaaatc acctagttaa agcaactaga ttgaatgttt
      481 atcataagtc tgatatcatg tttatgaaat gaaaaaagga gcggttatga tggaaaaaat
      541 gcgtcagcaa ttaatggagt gggggaagga actagaaaca ttccgtctgc ctcactggga
      601 agaactccct gacttagaac tttatatgga ccaagtcaga acgttagttg atcgttatct
      661 ttcacctgtg atacaaggag aaaagcatcc attgcttacc tcttctatgg taaacaatta
      721 cgttaaacta ggtttgatac cagcaccagt taaaaaaaga tataacaaag aacacgtagc
      781 atttttactt gcaatcacta cgttgaaaca agtattgact attcctgaaa tcaaagaagg
      841 gatattgttc caaggaaaaa cagtaggaat tcgtgaagcc tataatctat tttgcgatga
      901 acaagaagca gctgtgtgga tggtcagcca attagcacaa ggtaaatctc atccgcaaaa
      961 attcgaccag gcaacccctg tagaatatat tgctgtaaga gcggcaactt tatcgtttgc
     1021 aatgaaactt cttgcggaaa aaacgattgt tctagaaacc gaatatttaa aagaggagaa
     1081 aacaaatgaa aaacaataaa atcgcaattt tagtagattc aggtacggat gtgccagaag
     1141 aattgataaa aaaatacgag atgtatatga tcccattgaa aattatttat aaagatcagg
     1201 tatatacaga taaaattgac attacctctg aagagatcta tcaacgtttg ccagaggaaa
     1261 tccctggtac atctttgccg gatggtgagt cgatcacaga aatctttgag caaatcaaaa
     1321 aagacggtta tgaaaaggta cttgcggtaa caatttccag tggattgagc gggacatata
     1381 atgtggttcg tttaattgca caacagcaag aagaattgga agcatatgta ctagatacga
     1441 aaaatattgg tattggtgca ggtttttctg cgatccaagc agcaaaatgg ctggaagaag
     1501 gagtagaatg ggatcaactg atcagtaatc tgaatgagtt agtcgaaaga acaaaagttt
     1561 tctttaatgt tgcgacattg gaatatcttc aaaaaggtgg acggatcggt ttagttgctt
     1621 ctattgtagg aaccgcttta aagcttaacc caatcatctc atgtaatgaa gaagggattt
     1681 attacacagt aggaaaagct aggggacgta aaaaaagttt ggataaaacg gttgcttacg
     1741 tcaaagaaaa aatcggtaat gcaaaggtct tcaacttagc tgttgcccat ggggatgcga
     1801 aagaagaagc aattgaaatg gaagcgagac ttaaaagaga gttcccacaa gcaaaccaaa
     1861 tctactttgg ccagatttct ccggcattag tagtccacac tggtccggga ttattgggtg
     1921 tcggtgtaca agttttagaa ggataaatca aaaaaaggaa acactgaggt gaaaatcagt
     1981 gttttccttt tttattgaag ttagaacaaa aaataataaa gtattttgca ctttcatttt
     2041 aattttctct tttgttttat aggcaaagat gaaacaaaag cagaaatacg gtataatgag
     2101 aaggtatgac aataatatat aagaggtggc tctttatgaa aaaagtttta gttgtcgatg
     2161 atgagaagcc gatttcggat atcgtcaaat tcaatttagc caaagaaggc tatgatgttt
     2221 atactgcata tgatggggaa gaagccttgg aaaaagttgc tgaggtagaa cctgatttga
     2281 ttttacttga tttgatgcta cctaaaatgg acggcttaga agttgctcgt gaggtacgca
     2341 aaacttatga tatgccgatc attatggtaa cagccaaaga ttctgaaatt gataaagtcc
     2401 taggcttaga gttaggcgcc gatgattacg tgaccaagcc attttccaac cgagaattag
     2461 ttgcacgtgt caaagcaaat cttcgtcgcg gtgccacggc tgcgaaggaa ccagaagagg
     2521 cagcacctgc ggaattgacg attggtgatt tgacgatcca tccagaagct tacatggtga
     2581 cgaaacgagg agaaacaatc gagttaacac atcgtgaatt cgaactactc ttttacttgg
     2641 cgaagcacct tggacaagtg atgacaagag aacatttatt acaaacggtt tggggttatg
     2701 attattttgg agatgtacga acagtggatg taactgtacg tcgtttgcgt gaaaagatcg
     2761 aagataatcc aagccatcca aattatttag tgacacgtcg tggtgtcggt tactatttgc
     2821 gtaacccaga acaggagtaa ttggatgaaa agaaaagtcc gcttttttcg atcagtcaat
     2881 tttaagatcg ctattacctt tattctgatt ttattgatct cgatcgaaat tattggtgcc
     2941 tactttatac gtggtttaga acgttccacg atcaatacat ttattaaaga tatgaatcaa
     3001 acggtggaat cattagcaac aacaatcagc ccggaattga atcgaaaaga taatgcagat
     3061 gatgaagagg taaatgcgaa tatcaaaaga tttattgaaa acagtgcgac tagcgatatc
     3121 atcgaaatac gggtcgttga cgaaaaaggg atcatccgag gaacaaccga tgtcaatgaa
     3181 caaagcgctg tgggaaagaa aaatgattat gttgatatca atgatttcac gactaaacgt
     3241 tatgttgctt tagataacga cgataaacgg gtgaatatca atgttcaacc gatcctgtcc
     3301 ccgaccggcg atgccgttat cggggctctt tacgtcaaaa gtaatatcga acaaaaatat
     3361 tcggaaatca ataacacagc agtcattttc tttactgcct cactaattgc ggcatttatt
     3421 tcaatgatcg tatctgtttt agttgctcgt tcgattacac agccgatcgg tgaaatgaga
     3481 gaacaagcca ttcgaatcgc tagaggagac tacagtcgga aagtcaaagt gcatggacaa
     3541 gatgaacttg gacagctggc tgataccttc aatcagttag ctgaacgtat tgaagaagct
     3601 caagatacaa tggaagctga acgcaatcgt ttggatagcg tgctatccca tatgacagac
     3661 ggcgtcattg cgacagatcg caggggtaaa gtcattacga tcaatgatat ggctgtttcc
     3721 ttgctagata tcaaaaacga ggaagcaatc ggacaatcga ttttgacact tttagatatc
     3781 gaagaagaat atacgttgcg gaaattatta gaagatccaa acgaaatggt acttgaccgt
     3841 tcaaccagta cattggaaag tgatcagatg atcttgcgag tagacttttc tatgatccgt
     3901 cgcgaatcag gttttatcag cggattagta gctgtcttgc atgatgtgac agaacaagaa
     3961 aaaacagaac gggaacgtcg tgaattcgtc tctaatgttt cccatgaact tcgtacaccg
     4021 ttgacaagta tgcgtagtta tatcgaagca ttgagcgaag gtgcgtggaa agacgaggaa
     4081 gtagcaccaa attttttgaa ggtaacgcta gatgaaacag accgaatgat tcgaatgatc
     4141 aatgacctct taaatctatc tcgcatggat acaggtaata cccagcttca attagaatat
     4201 gtcaatttca acgagttagt gaattttgtt cttgaccggt ttgatatgat ggtgggaaat
     4261 caggaaaaaa attataagat ccgtcgtgaa tttacgcaaa gagatctttg ggtcgaagta
     4321 gatacagata aaatcatcca agtagtcgat aatatcatga ataacgcgat caagtattca
     4381 ccagatgggg gaacgattac ttgtcgctta ttagaaacgc ataataacgt ggttttaagt
     4441 atcaccgatc aaggattggg gattcctaaa aaagatctga accgagtgtt cgagcggttc
     4501 tatcgagtag ataaagcacg tgcaagagca caaggtggga caggacttgg attagctatt
     4561 tctagagaag tgattaaggc gcatcgaggc gctatttggg cagagagcaa ggaaggaaaa
     4621 gggtcgactt tttatatctc gctgccatat gaaccttatg aggaggaatg gtgggaatga
     4681 gaatctctga aaaagtcgtt cgtataggac tcattttgat ggttgcgtta agcatatact
     4741 tctcttatgc aatctggctg agcccagcag gaaaaagttc aatcaacgta gatgagacaa
     4801 acactcaaat gatcgagtct caaagcaatc gaaaaacttc cgaagtcttt cttccgcttc
     4861 atgttacatg gcaccattcg ggaatgatcc aagaaaccaa cagtgaaaat ctcgtgtacc
     4921 gattgcaatt gatcatcgat aaagcaagat ttggaaagct ttctgaagta gtttcaggag
     4981 acaaatcaca gtttgaacag gtgaaaaatc tgaactctgg ttttgagttg gcctataatg
     5041 cgcctttttt gctaagagaa tacaaggaag catttgattt agatttagat gtgtcgaact
     5101 tggcaaaaga aagcgaaaat atgtatttta ctagaataca attcgatcaa ggaaataaaa
     5161 aaatccgatt tttgaattat tcgaaccatc tcgtatatga agcaaatatt tcgttgaatt
     5221 ggacagatat caataaagaa ttaacagcaa aagacacaaa atggacagaa atgacaacag
     5281 aaccatcgac gatcgacacg caatatgcta cgaaacattc gatcaaactg aaaaagtata
     5341 gttatatcct gtcacagcaa ccctatacac tttttagaaa tgcttttttc cagaaaccag
     5401 atagcgtgaa aaataatgat gaaagcaatg aattgatttt ttacggtggg aatgaaacaa
     5461 tgtctatcca ttcggaaacg caagtagttg attttcgtgg agagctgcca gagaaaaaag
     5521 aaaatgctag tgtattttct gaaagtttcc cctatattag caaattaggc agttctttag
     5581 ggaacctcag atattttgac cgcagtgaca atacgatcga ttatcggata ttcgtggaag
     5641 gcttcccggt ttttgggaca gacagcagag gacagattgg tgtggaagtt ggcggtgaaa
     5701 cgaatggttc tgtgcaagtg aatatccaaa ccagtttgaa tacgattcaa gtgccgatac
     5761 cttcagacga agaagtagaa cttgcaagta cgaatgaaat catccagcag ttaaaagcta
     5821 agggagcaga tagcaacaag attggttcag tgatcgttgg ctatacatgg caaaatgtca
     5881 aagaaacgaa tcgtgtcgtt gatctcttac ctgaatggta tgtgaaatat aaagataact
     5941 ggtattcagc taacgacctt ctggaaaaat tacctggatt ggaggcgaat taattggatt
     6001 tcaaaaaaat cgaatggata tttttcgtcg cttttttagg gttgaatgtg tttttattca
     6061 gcagttatca tgacgcggta taccaagaaa acaatgtcat tcgctctaat cagactgaat
     6121 caatccaaca acgtctggct agcgacgata tcacttacac ggggaagatt tcgtctgaga
     6181 acaagcaagg ctattatctt agcgcggagc agaccaatct tagcacttca ttagcgaatt
     6241 atcgcaaggc tggtaaaagc ggcttgctgg caagtggtgt gtttttagac ggtgatgttt
     6301 tgacgaaatc tttatccagt tcagatgctg aaaagaacgt gatcgatcca gataaaatta
     6361 gtagttcctt ggaagatttt ttatctaaca aagacaatat tttattcggt aatgattatg
     6421 tgtacacgaa aaacttttct catttagaag aagaaccact agaaatccaa gcaagccaag
     6481 agtatgaagg catcccattc aatgatgata cagcaaaaat cgttctttct ttagaaaaaa
     6541 acgataatga ttatagcatc acgaaataca tgcagacgca tttatctgat atcgagcagc
     6601 tgcgcgaaaa gacggaactg tatacggaag aggaagcaat caatacattg tacatcaata
     6661 acaaaatacc aagaggatca aaaattttat ggcgtcagct agcttattcc tgtattctga
     6721 aagtccggga aaaaaatgtg tatgttcctg tttggcatgt agcgatcgaa acaagcgata
     6781 aagtggtcca aattgagagt gtcaacgctt tcagcaatac gatcgtgaca aacaatactg
     6841 taccaaaagt ggaagatcaa taaaaaagcg agtataatga aaaaagttta caaagtaaga
     6901 agggaagtag gagtcaaatg gctgaagaaa aaccagcttt taaaatcagt atcctagcaa
     6961 gtggaagttc gggtaattca ctttatatcg aaagtgaaaa aaaacggctt ttggtcgatg
     7021 caggacttag cggtaaaaaa atcacttcct tgatggctca aattgatcgg acaccggacc
     7081 aattagatgg aatacttgtg acgcatgaac atcgagatca tatacatggc gtgggtgtct
     7141 tggctcgtaa gtatcatttg gatgtttttg ccaatcagca gacttgggaa gcgatggaac
     7201 cactgattgg aaatgtacca gtggaacaaa aacatctatt tgagatgggg aaagtcagaa
     7261 cattcggcga tatcgatatt gagagtttcg gcgtctccca tgacgcagcg gctccgcaat
     7321 tttatcgttt ccataaagaa aatcggtcat tcgtcatgtt gacggacacc ggatattgca
     7381 gtgattatat gcgaggtgtc attgaaaatg ccgatggtta tttgatggaa agtaatcatg
     7441 atcttgagat gttacgcatg ggaccttatc cgtggaattt aaaacagcgt attttaggag
     7501 atagaggaca tctttccaac gaagacggtg cacttgtcat gactgatgtg atcggtaatc
     7561 ggaccaaacg aatctatctt ggccatctta gcaaggaaaa caatatgaaa gaacttgctc
     7621 atttaacaat ggaaaatgtt ttgaaagaaa aagattttgg cgttggacat gattttgaaa
     7681 tctatgatac agatccagat gaagcaactg agctattttc gatttaaaca gttcaatcaa
     7741 taaaaatata aaaagcagaa gataaaatca atcagggttg gttttatctt ctatttttat
     7801 ttttttagca tattaaaaaa ataaccgtat tatcgactga ctacactgat gtgctgcttt
     7861 tcatgtttct catccagtat ctcatctact aatgcaatcg cgtaatctgc catgctgatc
     7921 gtactgtcgc cagcagcgtt tctttgtaaa taatcatcac ttaacaaata agtacctgta
     7981 cgtttgccat gtggatcaaa taaagaagct ggactgatat aagtccaatg tagattttta
     8041 gattgtttca attttaacaa tccttcgtac atattgaaag ctgttggata gaagggtgca
     8101 tttttaggta cttggtcaat catacgagtc gtcttttctg tatctaagaa taacgaagag
     8161 gcacccccaa cgacaattaa gcgtgtatcg gttccttcaa gcatctcaat caaatgggac
     8221 aaagaagttt gatgcatttc ttcttttcct ttgggagcgt tgaaagcatc aacgacaaca
     8281 tcaaaagatg caagatcagt agttgtcaac tcaaataaat ccttttgtat aaacggaaca
     8341 tctgatggca atttttctgg atgacgcacg attgccgtca cgtctaaatc tctggacaat
     8401 gcttcgtcta aaataaatga acctgcatgg ccagtagctc caatgagtgc aattttcata
     8461 aaaaacctcc ttttttattc ctgtccattg taagcagttg ctgaatattc gtcaaagaat
     8521 ccgatttttg aaaagctcag tgcgcattcc tttcatggtt cgtgatcatt gggtatagtt
     8581 aaattaagaa aactgattga taaaaataga agttgaagga gataagaaat gaaagagtgg
     8641 ttagatcgtg cctttttacc aatgataaca tctgttgtga atcttagacc cttaactgct
     8701 ttgcgtaatg gaatgactta cacgatccca ataattattg ttggctcgct gtttttctta
     8761 tttgctcatt ttcctgtgga ttacatcgct cagtggatag acaaaacagg attttctatg
     8821 tattttacac aagtatacca ggctacattt gatgtgatag ccttttggat cgtttttgcc
     8881 attgcatacg cttatgcaaa agaagaagac atcgatcgct taccagtcgg cataacagcc
     8941 ttgtctgctt atctactgct tattcagcca ctaaatactc agatagatac tgtctggaca
     9001 ggtgctgaag ggatactagg agcagttaca actgggctca tcatcggatg gggctatgca
     9061 cgtttagtaa gacttgcgaa agggtggaag caaagagaga agatacctga aaatgtttgg
     9121 cagtctttta cttcattgat tccaatcatt gttatagtca cttttacgct tatcggttca
     9181 gcggtttttc aacagttgtt cagaatgact gttgttcaag gagtatggac atatgtccag
     9241 cttcccattc aatcgttcat agacacgttg tttggtgtgc ttttattagg tttttttgtt
     9301 ccgtttttat ggttatttgg tcttcatgga tctgcgatgg tcaatgggtt ggttagtccc
     9361 gtcttgcaag cgaattcatt agcgaatgca gaaatcttag cctcaggaca agagttgacg
     9421 gtggcaaatg gcggacatat cgttactcag caatttctcg atcagttcat gacggttacg
     9481 ggtgctggat tgacgttagg ggctgtattt tttatgacgg tttttgcgaa atcgaagaaa
     9541 tacagagaat taggaaatct tgctctttta ccagcctttt tcaacatcaa tgaatcaatt
     9601 attttttcca caccgatcgt gatgaacccg atgatggctg ttccttttat tttcgcaccg
     9661 gtcgtttcag gattgattac ctattccgct ttatattttg gattcgttcc tttatttaca
     9721 gcagtccaag tcccttggac aacaccgccg atcctctcgg gtttcttagt aggcggagtg
     9781 cctgcagcga ttttacaagg tatcgtgttg tcaattagtt ttttcattta tttcccattt
     9841 ttgaaaaaaa tagattctgc aaactgcaaa aaggaaagac agacaaaaaa tgatggagca
     9901 gcagaaaaga tgaacgacta aaaaacaaaa atactcctgt cgctttagat tgggaaaatc
     9961 accaatctag gatgacagga gtatttatag tcatgtttat actagccctt tttggacagc
    10021 taattgaaca agaacaacta atgtgttcat tcctacgtgt gtgatcatcg atgtccagat
    10081 ccgaccagtt gctttgtact ctaggctgaa gaagaaacct aggaaaaagt agattagcag
    10141 atgaccatca ttatgagcaa acgcaaacag caaagagctg atcactgctc cgacccaaaa
    10201 atttgaatat cgactgatga tccccagtat actgcggcgg aatacgaact cttccatgat
    10261 gggtccagca acagttgtcg ccaaaataaa agcgggtgct tccatgatca tctggatgat
    10321 attttgtgta ttctcggaag gggttgcttt gccaaacaat acagattcta acatgacagc
    10381 gatgctttgc agaatcaatg cgacaaagat tccaaccaat ccataaataa caatctttgg
    10441 agcagaagct ttttttaccg ctgattcgat cgctaagggt tcacgttgct taaaataaaa
    10501 aatagctagg acaacggcgc ctagtatata catgactgca gttgctgtga tcaattcaga
    10561 cgtagatttt acaagtccta tcgaagctag gatcaagggt gagataaaaa ttagaccata
    10621 gcaaaaaatg ctgaggaagc tatatttttt taaagacatg taattcctcc ttttaaggga
    10681 taacaagcat gcaaggcaag cttatatcga ttgatttcaa ttatatcata atttcaataa
    10741 gcagctgtca gaataaaatt tcttttcttt gatttaaaag cttgcaaaaa agagggagaa
    10801 tgagtattat taaaaatgta ggttagcact cgaaggttaa gagtgctaac agattaaaaa
    10861 aagagttatc ggagggattt atcgtgttaa aaccattagg tgatcgcgtc attatcgaag
    10921 tcgcaaaaga agaagaaaaa actgtcggag gaatcgtttt agcttctgct gctaaagaga
    10981 aaccccaaac tgggacagtt gttgcagtcg gtgaaggccg tttgttagaa aacggtgaaa
    11041 aagttcctgc cgctgtaaaa gcaggcgacc aagttatgtt cgaaaaatac gccggtacag
    11101 aagtaaaata cgaaggaaaa gaatatctga tcgtcgcagg aaaagatatc atggcgattg
    11161 ttgagtaaat ttggaagata aaaaaataat caaaaataat caatgaggtg aatcaatcat
    11221 ggcaaaagaa ttgaaatttg cagaagacgc acgcgcagct atgttacgcg gggtagataa
    11281 attagcagat acagtgaaag taacattagg acctaaaggc cgaaatgtcg tactagaaaa
    11341 atcttacggc tctccattga tcacaaatga tggtgtgacg atcgcaaaag aaatcgaatt
    11401 agaagatcat tttgaaaaca tgggtgcaaa acttgtatca gaagtagcat caaaaacaaa
    11461 tgatattgca ggagacggta caacgacagc aactgttctg acacaagcaa tcgttcgcga
    11521 aggtttaaaa aacgtaactg caggtgctaa tcctctaggc attcgtcgcg ggatcgaatt
    11581 ggcaacaaaa gcagcagtcg aagaattgca taatatctca actgttgttg attcaaaaga
    11641 agccattgca caagtagcag ctgtttcttc gggttctgat aaagttggac atttgattgc
    11701 tgatgcaatg gaaaaagttg gaaacgacgg tgtcatcaca atcgaagaat caaaagggat
    11761 cgaaacagaa ctagatgttg tagaaggtat gcagtttgat cgtggttact tatcacaata
    11821 tatggtaaca gataacgaca aaatggaagc tgttctagaa aacccatata tcttgatcac
    11881 agacaaaaaa atctctaaca tccaagatat tctgccattg ttagaacaaa tcttgcaaca
    11941 atcacgtcca ttgttgatta ttgctgacga tgtagatggt gaagcattgc caactcttgt
    12001 attgaacaaa atccgtggaa cattcaacgt agtagctgta aaagctcctg gtttcggcga
    12061 tcgtcgtaaa gcaatgcttg aagatatcgc tattttgaca ggtggtacag taattactga
    12121 cgatctaggt ttagaattga aagatgtaac aatcgaaaac ttaggaaatg cttctaaagt
    12181 tgttgtagat aaagacaata caacgatcgt agaaggttct ggagaaaaag aagcaatcga
    12241 agctcgtgtg caattgatca aaaaccaaat tgctgaaaca acttctgatt ttgaccgcga
    12301 aaaattacaa gaacgcttag ctaaattagc aggtggtgta gctgttgtta aagttggtgc
    12361 agctactgaa acagaattga aagaattaaa attacgcatt gaagatgcat tgaatgctac
    12421 acgtgccgca gtagaagaag gaatggtctc aggtggtggt acagctctag tgaacgttat
    12481 cagcaaagtt tctgctgtag aagcagaagg agacgtggca acaggtatca agatcgttgt
    12541 tcgtgcttta gaagaaccaa ttcgtcaaat cgctgaaaac gctggttatg aaggatcagt
    12601 gattgttgat aaattgaaga acgtggaact aggcactggt ttcaatgctg ctactggaga
    12661 atgggtaaac atggttgaag caggtatcgt agacccaact aaagtaacac gttctgcctt
    12721 gcaaaatgcc gcttccgttt ctgccttgtt attaacgaca gaagcagtcg ttgcagataa
    12781 accagaacca gcagcgccag cagctcctgc aatggatcca tcaatgatgg gcggtatgat
    12841 gtaagaaaaa gcaacttgct tatctacaac tgatcattag tgaaagacag ataaaaagag
    12901 gctggaacag aagcgtttaa ctccaagaaa taagaagaaa ttcacggaaa ttgcttttca
    12961 aatttttgtg aatttcagct tatttccgaa ggagttgctt ctgcttccgc tgtttatacg
    13021 tgtttagagc gtgagacaaa agtgttcttt acttttgtcc cacgctcttt tttgtgtgta
    13081 attataatga aaatagttat ttttaatagt tataatattt tatctattaa aagtaaatat
    13141 ccattc
//
LOCUS       DAXQKX010000070        13143 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.072, whole genome shotgun sequence.
ACCESSION   DAXQKX010000070 DAXQKX010000000
VERSION     DAXQKX010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13143
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.072"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(227..469)
                     /gene="acpP"
                     /locus_tag="ACF3MF_002311"
     CDS             complement(227..469)
                     /gene="acpP"
                     /locus_tag="ACF3MF_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFE3928252.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            complement(591..1592)
                     /gene="plsX"
                     /locus_tag="ACF3MF_002312"
     CDS             complement(591..1592)
                     /gene="plsX"
                     /locus_tag="ACF3MF_002312"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HFE3928253.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            complement(1641..3677)
                     /gene="recG"
                     /locus_tag="ACF3MF_002313"
     CDS             complement(1641..3677)
                     /gene="recG"
                     /locus_tag="ACF3MF_002313"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HFE3928254.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            complement(3794..5476)
                     /locus_tag="ACF3MF_002314"
     CDS             complement(3794..5476)
                     /locus_tag="ACF3MF_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HFE3928255.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPEV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            complement(5528..5890)
                     /locus_tag="ACF3MF_002315"
     CDS             complement(5528..5890)
                     /locus_tag="ACF3MF_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFE3928256.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            6160..6348
                     /gene="rpmB"
                     /locus_tag="ACF3MF_002316"
     CDS             6160..6348
                     /gene="rpmB"
                     /locus_tag="ACF3MF_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HFE3928257.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            6586..9255
                     /locus_tag="ACF3MF_002317"
     CDS             6586..9255
                     /locus_tag="ACF3MF_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HFE3928258.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDGGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(9588..10334)
                     /gene="truA"
                     /locus_tag="ACF3MF_002318"
     CDS             complement(9588..10334)
                     /gene="truA"
                     /locus_tag="ACF3MF_002318"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFE3928259.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(10537..11334)
                     /locus_tag="ACF3MF_002319"
     CDS             complement(10537..11334)
                     /locus_tag="ACF3MF_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HFE3928260.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            complement(11324..12193)
                     /locus_tag="ACF3MF_002320"
     CDS             complement(11324..12193)
                     /locus_tag="ACF3MF_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HFE3928261.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            complement(12169..13008)
                     /locus_tag="ACF3MF_002321"
     CDS             complement(12169..13008)
                     /locus_tag="ACF3MF_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HFE3928262.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMIFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
BASE COUNT         3649 a         2859 c         2343 g         4292 t
ORIGIN      
        1 ataaaaaagg acattacaca gaataaatcg ttttataaca aaggttattc ttatctttgt
       61 gtaatgaatt attaataatt atatagaaaa ccgctttact ttgcaacata atttctgttt
      121 atcgccagaa ttatcagaaa aatgactttt acgtgtcaaa aagattaaaa aaagaaggat
      181 aaaaagctgc atgcagcttt ttatccttct ttgcttttat ttgaaattat ttaagatggc
      241 tgctgatata atctactgcg ccaccgactg tttcaatttg ttcagcgtct tcatctgaaa
      301 tttccgtacc gaattcatct tcaagctcta aaacgaattc cataatacta attgaatcag
      361 cttttaaatc atctttgatg ttcaattcat ccgtcacttt atcggtatct atctcaaaat
      421 gatttgaaat aattttcgct actttgttaa atacttcttc gcgagtcaac tttttcacct
      481 ccaagaatca tacacttgtc aattacctac accatggcta attttactgg catttttcag
      541 gaatgtccac ctttttttca atggaacgga tcgcttcaga tatccaaata ctattcttcg
      601 cttttttcaa attgttcgac taattgtcca actacatctg tctcaagcat tgtgtggatt
      661 tggcggatcg tatagcgaac agcatcgggg cctgttgctc catgagtttt aatgactggt
      721 gctttcaagc caaacaaaac ggcaccgcca tgtttggaat aatccatttc tgctttcaaa
      781 gaacgtaagc cgtcttttaa aagcatagcg cccatttttc ctttgatccc ttcatttaga
      841 atagcagatt ttaatagatt catcatattc attgctgttc cttcaataga tttcaaaaca
      901 gcgttgcctg taaatccatc tgtgaccact acatcagcca caccattgag tagctcacga
      961 gcttctacgt ttccaataaa attcaagctt gtttcattct gaaggagttc ataggctttt
     1021 ttcgtcactt cactaccttt tgttgcttct gttccgttgt ttaagagtgc gacacgagga
     1081 cgtccgatac ctcggacttt acgtgcataa aaagaaccta aaataccgta ttgcaacaaa
     1141 tgttctggtt tgttttctgc gttagcgcca agatccagca tatcgaaacc ggcaccttct
     1201 ttccctacta ctggcaaggt agacatcaag ccagggcgtt cgatattttt gatacgtcct
     1261 acgatgaaca accctgctgc tagtagcgcg cctgtattcc ctgctgaaaa tacagcatct
     1321 gcttcaccgt ttttcactgc ttgtgcagca aggaccattg atgcagtctt ttttcgtcga
     1381 attgctttta ctggctcatc atcactattg attttttcgt ctgtatggat aatcgtgatg
     1441 tttttttcat ttgttaagta tttcttgatt tctgcttctt ttccgtaaag taagaattct
     1501 acttctggaa aatcttgctg cgctaaagcc acgccttcta caattgcttg aggtgcgtga
     1561 tctccgccca ttgcatctac ggcaattttc attgtttcca ctcctttttc cgtcatcagt
     1621 ataaagtata gcacagtctg ctaatcgaaa taacgattat cctgattttc tatttggagg
     1681 ctttgcgcta aaggctgata ctcaggaagc atctgccaat cctttatttg ccaaagggct
     1741 gcagcctctt ctctggctac ctccaaaaca tttccatccg tcaccaagtc agcaatcgca
     1801 aattgaggca gaccagattg acggaagcca aatacttcac caggaccacg taattccaga
     1861 tctttttcgc ttagtacaaa accattggtg gtctctgtca tgattttcat ccgttccaca
     1921 cctagttcat ttttaggatt agcaactaag atacagtagg aagcatcact tccgcgtcca
     1981 acacgtccac gaagttggtg cagctgtgcc aatccaaatc gatccgcatc catgatcagc
     2041 atgacggtcg cgttcggcac gtttacccct acttcaatta cagtagtcga aactaatatc
     2101 tgcatctggt tgtctttgaa ggcttccatg attacttctt tttcctgatt cttcatttta
     2161 ccatgtaaca agccaacttc atattttggt gcaaatagtt cacgaagttt ttcatagatt
     2221 tccactgcat tttttacatc taatgcttct gattcttcaa tcagcggaca gatgacatac
     2281 atttgatgtc ctcttgccag ttcttttttc gtccaatcca gtacactgtc caattgaggt
     2341 gttcttaccc agcgtgtttc gatcgggata cgtccagctg gaagttcatc aatgatagat
     2401 acatccatct caccatatgc tgtaatagct aatgttctag gaatcggagt cgctgtcata
     2461 aataagacat ctggtcgcca gcctttttca cgaagtactt tccgctggtt cacgccaaaa
     2521 cggtgctgct catccgtaat aactagacct aaattctgaa attcgactcc atcttggatc
     2581 aatgcatgtg tgccgatcac gacgttaatt tccccttgct ctagtttttc aaggagctca
     2641 cgtcgttctt ttgctttcgt tgaccccgta atcaatgcga tggttacttc attgggatca
     2701 aacagctgtt gcaagctttc catatgttgt tgtgccaaga tttctgtagg caccatcaac
     2761 gcaccttgga aacctgctgt aacggtagcg tataacgcaa tcgcggcaac cactgttttt
     2821 ccgctaccta catctccctg caaaagtcgc tgcatatgct gcggactgcg aagatcccga
     2881 cagatttcat tcgttacacg tttttgtgca tttgtcagtt caaaaggtag cttttgagta
     2941 aattgtttca atttttggac atcataaagg atctccaaac cattcgtttc tgctttttct
     3001 gcttttttca atccttgaag acgcatttga aataaaaaga actcttcaaa aacgacacgt
     3061 cgtttggctt gatggttttc ttcgtggtct tttggaaaat gcatacttct tacagcagaa
     3121 gctcggtcaa gcagtcgata tttctccaca aggttgtttg gcagattttc ttcaatcaat
     3181 gtgccgtatt cttgaaaccc ttttttgatt agatcaacta atgtcgtttg acgaattgat
     3241 ttgttgacgt gatatatcgg cgaaaagtca tccattgttt gagaacctaa aatcttcatc
     3301 ccgttcaagg ctttacgctt tgcatcccat ttaccgtata cggcgatttc ctccgataaa
     3361 atgacttttt cttttagata aggttgatta aaaaaagaaa cgttgaacac atcatgttct
     3421 tgcatcatac gaaattgcaa tcggcttttt ttataaccaa atcgattcat cacaggaggc
     3481 gagactacga ttcctttcaa agtaaccttt tcttgatcct ggatctcgtt tagatttctt
     3541 tcctgaatat cttcgtagcg aaaaggataa taagtcagta agtcttcaat cgtttggatg
     3601 cccaagctgg caagactagc tgctcttttt tctccgactc ctgccagcat agtgattgga
     3661 tcatctaaag aacgcataaa tttttcctcc ctcctttaac aaaaaaagga cttggtcagc
     3721 gatcatacct gatcactaac cgaaggcctt ttatgaatga atactgtgtt agaaagatat
     3781 tctgacacag aaattattca gcagaaaata gataaggata gacaggctga tctccttggt
     3841 ggatctcgat ttccaaatca ggatgttttt ctgttagttt ctcagcaaat tcatttgctt
     3901 gttcaactgt tccttcatca cctgccaaga tcgttacgat ctctgtgtcc tcattgatca
     3961 tttgttctag tgtacttaac gctgttgctg tgatatctgg gttagagatc aggatttttc
     4021 catcgatcat gcccaaaaag tctccttctt tgatctctac accgtcaatt gaggtatctc
     4081 tgatcgcgtg agtgacttga ccgctcacaa cgctagacaa catttctgtc atcgtttctt
     4141 tgttttcttc taaagaagct tgatcattga atgaaagcat agctgtcaat ccttgggaaa
     4201 tcgttcttga aggaacaact gctactggga tatctgctac ttctgctgct tgatcagctg
     4261 ccatgaagat gttcttattg tttggcaaga caatcacttt atctgcgttt acttcttgaa
     4321 tcgctttaac aatgtcttcc gtacttggat tcattgtttg tccaccactg ataacataat
     4381 tagcgcctaa actttcaaac agctcttgga cgcctttacc agcagcgatc gctacgatac
     4441 catacgggat acgtggtatt tcttttttcg caaactcgtt cacttcttca tcgtgttcca
     4501 aaatcgtctc atgctgcaag cgcatgttgt cgactttgat tttgactaat gaaccgaatt
     4561 tttgtccata attcaagact tctcctgggt tttctgtatg cacgtggact ttgatgatct
     4621 cgtcatcatt gaccacaagt aaagaatctc ctataccatc taaatagtta cggaattctt
     4681 cgtaatcgaa tgtactatcg actgtaggtc cttctccgat ttttaccatg atttctgtac
     4741 agtaaccaaa atggatatct tctgtcgcca tttgaccttg gacactgcga tgatgttctg
     4801 cattgaccat atcatccatt tctgctggag aaggttcata tgtttcatcc gcttggaatt
     4861 ctccattcaa tgcacttaaa aagccctcat aaacaaacag cagtccttgc cctccactgt
     4921 ctacgacacc gacttctttt aggactggaa gcaagtctgg agttttagct aaagcacgct
     4981 ttgctccttt tacaacagct gtcattactt caacgacatc atcagtactt tttgctttct
     5041 tttctccagc tttcgctgct tctctagcta ctgtcaaaat cgttccttct actggtttca
     5101 ttactgcttt atacgcagtt tcaactccat gagtgaaggc tgcagcaaga tcagaagcat
     5161 ttaatgagac aacttctgga atttgcttag aaaatccacg aaacaattga gacaaaataa
     5221 cgccggaatt tccgcgcgca cccatcagca atccttttga aagcattgct gctaattctc
     5281 ctactttttc tgaggttgaa tctactactg ccttagctcc actagtcata gatagattca
     5341 tatttgttcc cgtatcgcca tctggcacag ggaatacatt taatgaattg acgtattctg
     5401 catttacttg cagacgattc gcacctgcct ggaccatttc ctggaactgg cttgcactta
     5461 tttctgttac actcacctag ataatcctcc ttcagatcga ctgctgagtt accagccagt
     5521 ctcctgccta gtctggcagt acacgaacac cttgtacaaa gacattaact gaattggcag
     5581 ttacgcctaa taatgcctct agattgtatt tcactttttc ttggacgttg cgggaaactt
     5641 cagagatttt cgtaccatag ctgataatcg tataaacatc tacagcaata ccattatctt
     5701 cttggcggac aactactcct cttgagtaat tttctttacg caaaatctca gtaatattat
     5761 ctttaatttg atttttgctg gccattccta caacaccgaa cacatctgtc gcggcgccac
     5821 caacaactgt tgcaattaca tcattggtaa tttcaatggt tccagctgac gtttgaattt
     5881 ttacagccat gaatgagcct ccttaacggg taaaaaactc ccatttttct tctatcatat
     5941 tttatcatag cgcaacttga aataaaaggc agttacccaa agtactcaaa aaccttgcaa
     6001 aatttcaggt ataaccttgt ttaatttaca attattcttc tcaattgtca attgtatcta
     6061 tgaaaatgta cttgcaaatt cccattctat atgatatgtt agtctggtat gagctgaatt
     6121 attctattgc tccaaatcaa ggcaaaggag gaaattacca tggcaaaagt ttgttacttt
     6181 acaggtcgca agacaaaaag tggaaacaac cgttcacacg ctatgaactc aacaaaacgt
     6241 actgttaaac ctaacttaca aaaagttcgc gttatggtcg acggaaaacc taaaaaagtt
     6301 tgggtgtcaa ctcgtgcttt gaaatcagga aaagttgaac gcgtttaatt gaatgatact
     6361 tggaccgttc agatagtgaa cggtttttta tttaataaaa atttttaagg gtgggacttt
     6421 tgattcctac cctttttttg cgtttatttt tgttatacga acaaattatg aagttattta
     6481 ttctaaattt tatttttttg tgaaaactag actcttttta agcagagaaa aacaaggata
     6541 tgataaactg aatacaactt catagaaatt tggtggaaaa taaatatgaa aaaaaattta
     6601 aagtcattct ttagagaaaa cggacgctac gcagcagcta gtttcctgat tccgtttttg
     6661 attttagcac ttgtttatct aagtatcgga atctatcctg gaagcagcag aagtattttg
     6721 gcaagtgatg ccttttcaca gttttctaat tttcatgcca gcttccgaaa tgttcttctt
     6781 ggaaagcaaa gtatttttta tacatggaat gcttctctag gattgaatta tttatcttta
     6841 atttcttact atctaggcgg gatcttcacg ccactggtgt tcttttttcc aaaccagatg
     6901 atgccagatg cactgtatgt tctgactttg cttaaggtcg gctgtgccgg attggctttt
     6961 tggtttcttg cacgtacgtt caagattcct cgctgggggc atgttgcact tagcgtcagt
     7021 tacgcattga tctcatttat cactgcacat tcggagatca tcatgtggct ggatgcattt
     7081 gtttatcttc cattagtgat tttggggatt catcgtgtta tggatcttaa acggccgaaa
     7141 cttttattta tcagttattt actcttgttt ttatccagtt tttatatggg ttttatgatt
     7201 ggcgtatttt ctttcttata ttttatcgcc cgtctattga caaactggtc agaatataaa
     7261 aaaacgattg ttccttatgg tatcacttct ttactggcag gcggcgcttc aatgatcatt
     7321 gtattgccag cagtgctgga tcttcggtca aatggcgagg cactgagtca gatcactacg
     7381 ttgaaaacag aagcgacttc ttatctggat ctaatcatga aaaatatgat tggtgtttat
     7441 gacacgacaa aatacggatc gattccgttc gtttacgcag gtctgctacc attagtcctc
     7501 tgtctgtttt attttgccag tcggaaagta ccgttgaaaa ataaattttt gtacggcagt
     7561 cttttcgcca tacttatcgc aagtttttat cttgttccat tgaatttgtt ctggcatggt
     7621 atgcatgcac cgaatatgtt tttattccgt tatgcctatc tgttctcttt cttagtgctc
     7681 ctgcttgcag gaaaaggatg ggaaaagata gaacaagacg atggtgggct gttgttagga
     7741 atcattttgg tcgtagctgc tctctttgcg gtggcatggg gcatcaaacc tgaaggaagc
     7801 tacacctatg tgacgatgac ttcctttgta ttgacagtgg ttttcttagg gatttatgct
     7861 tttgctgtgg gattttatca gcataaaaaa ctttcattca atcatctgag tatattgtta
     7921 ttattgatca tgtctgctga agcactggtc aatacgaaca gtatgatcca tggcattctt
     7981 gatgattgga attatgcttc ccgcagttta tatactgatc cttatcctga cttgaaagct
     8041 cttgtaaatg aaacaaaaaa agattccgac tcgttttacc gcttggaaaa tctggatcca
     8101 gtatctgcaa acgattcgat caactatggt tacagtggta tcagtttgtt ttcttctata
     8161 agaaatcgta attcttcctc ttacctggat aaattaggtt tccgttcaag agggacaaat
     8221 ttgaatatcc gttataacaa taatactttg ctgatggatg ggtttacagg aatcaaatat
     8281 aacatttcta aaaacgaaag cacgttcagt aaatatggct tccgccaagc tggtcaaagc
     8341 ggcgactata cactgtatca gaatgtcaat gcattgccac tagcatttac tgcaccgttg
     8401 tccgttaatg atgttgagca gccagtgaca gataatttga ccagtcagac aaacttgatc
     8461 aatacattgt ctggtctaaa tgaacagtat tttacattct atacacctac tttgaagaat
     8521 cagttgaata cgacgatcac aaagacaacg actggcgtca cttactcaga aacagcagat
     8581 aaccagccaa aagagctcac ttgggaagtc catgtgcctg caaatacaca agcttactta
     8641 agtttgttcc caaccaattt tgcgcaatta gaaagttcta gtgcgacgat cactgtcaat
     8701 ggtacatcgc gaaaaacgca aatcaacatt tctggtcaat actatgatct tggctattat
     8761 cctcaagaga caacagtgac atttactgca agtttttatg ggacgaaaga aataagtttc
     8821 atggagccta aagtcgttgg tctagatgtt gtagcctatc aagccgcaat gaatcagatc
     8881 aaagaaaaag gtgtcgaaat ggaagccact ggcagaaaag cttctgggac tgtaaatacc
     8941 gctgaagatt ccatgttggt gacaactatt ccttatgaca aaggatggaa agctaaaatt
     9001 gatgggaaac cagtcaaggt cagcaatttc aaagacgcat tcttgatgat aaaagttcca
     9061 gcaggtaaac atactgtcac tttcagttac ttgcctgaag gatttacgat aggtgcaatc
     9121 ctttttgtcc tatgtattgc attgtttatt ctttatgtct ggtaccttga ccgcaatcgc
     9181 cccttttatg gcacgattga tccagcaata gaagaacaac cacgaaacac acacagaaga
     9241 agacgtagaa aataaagaaa cgatggaacc tgttcagact gtccgcacca agggcaatca
     9301 aaacaacgtt ccatcgtttt ttggttacag aaaaaatagg taacaaaaag atgattcact
     9361 tatcaacgcc tcgtccacaa gtcacgatat tcatcaaaga tgagaagctg ttttttgaaa
     9421 ttgctctttg tgactcagag ttaaatgaca ggctcacgac ctctttctta aacggtgttc
     9481 cagaagtagc ttcttcgaaa ataagccgaa attttgcaaa attttgagaa gtaattttcg
     9541 taaatacctt cttatttctt gaagctgacc acttctatca taacctctta ttcatatttc
     9601 acttcataca aataaagtcc ttcagggtgt gctgtaggtc ctgctgcatt acgatctttt
     9661 ttcgcaataa tatctgggat actatcttca ggcaatcggc cattgccaat tttcaaaagc
     9721 gttcctacta agatccgtat catcttatac aagaagccat ttcccctaaa tgtaaacaac
     9781 aattcgtctt ttgtttcatt tacctccatc ttagcctcgt agatcgtacg tattttatcc
     9841 tctatcgagc ttcctgatgc acaaaaagag gtgaaatcgt gagtccctaa taaatcagga
     9901 agcgcccgct gaattttttc caaatcaagt gggtaaggaa aataacttgc ataatggcgt
     9961 cgaaaaggac tgcgtggttt ccctatatcc actcgaaatt gatacgtctt ttctttgacc
    10021 aaatatcttg cgtggaagtc ttctgaaaca atttctactt gtcttacagc aatatcctct
    10081 ggtgactggg tatctagcgc gaaacgcatt cgttctaacg gacgctcctc tggataatca
    10141 aaatggatta cttgcccgat cgcatgtact ccggcatctg tccttcccga accaaagacc
    10201 gtgatttctt ttccatttgc cattttttgt aatgtttttt ctacttcttc ttgaacagta
    10261 cgcccatttg gctgtttttg gaatccatta aaatttgttc cgtcgtacgc aatgattgct
    10321 ttgtaacgta ccatgttttt ctctcctttg ttcctaaaag gttatctgga ataatgattt
    10381 ttctataaaa ttttttcgtt ctttcttttc agataaaaga aagaggcctg tgaccttagt
    10441 ctgccacaga ccctaatatt tcttgtcata cactgcttgc atcctttctt gcaaacagat
    10501 cagcaagaaa agaatagata gcggcccact gaacgtttat cctcttaaaa agatcagtag
    10561 cacagttaat aatacaaaag caatgataac catcgtgtct ctattatgcc aatgcaatac
    10621 acgatatttc gttcttcctt ccccaccttt gtagcctctt gcttccatag cagtcgcaag
    10681 atcttccgca cggttgaagc tgctgacaaa taaaggaatc agcaaaggaa tgactgcttt
    10741 cattttctga actaggtttc cttcaccaaa atcaacaccg cgagcgcgct gagcgttcat
    10801 gatcttttct gtttcgtcca tcaatgtagg cacaaaacga agagcaatcg acagcatcaa
    10861 tgaaatttcg tggactggga accgtacggc tttcaatgga cgaagcaagt actcaatcgc
    10921 atccgataat tccaaaggcg gtgtagtaag cgtgagtaga gtcgacataa aaatgatcaa
    10981 cacgaatcga cagaaaataa agaggccgtt catcacacca aattcagtga tatggaaaac
    11041 accccaactc caataagttt ctccgccact tgtaaacaag acctgcaaag ctacagtgaa
    11101 gaggattagc cagatcaatg ggcgaatgcc tcggataaaa aatttcaaat ctacttttga
    11161 caagaagaca gaaagtaatg tgaaaaatgc caacaaaagg tacgtttccc aattatttgc
    11221 taaaaaaatg attccgataa aataaaaact ggctaataat ttagctcggg gatccaatcg
    11281 atggatcaag gaatctccag gcatataacg accaaatatc aatttattca tcatgggcat
    11341 ttcctccagc ataatggacg atagcgtctg ctaattcttc agctgtcaaa ggcaaggtag
    11401 caaagttcat ccctttagcc attaattctt ctgcaaactc ggtggcagta ggtacgccta
    11461 gttgtttttc ttttagccat tcaatgtttt gaaagacctc ttgcggctcc ccgctattaa
    11521 cgattcgtcc cttttccaac acatagacat aatctgcaaa attggctaca tcatccatta
    11581 aatgcgtaac taatacaata gtgatctgct gttccttatg aagacgccaa aacatctcca
    11641 tcatttcttt tctgccctgg ggatcaagtc ctgccgttgg ttcatccaat acaagtactt
    11701 ccggcctcat ggcaagcaca ccagcgattg ctactctacg catttgccct cctgaaagtt
    11761 caaatggcga acgttccaaa tagctttcat ccagcccaac ttgttctaat gtttcttttg
    11821 ctaggactag tgcttcttct tcgctgacac caaagttttt aggaccgaaa gcaatgtctt
    11881 ttgctaccgt ttcttcgaat agctgtgctt ctggaaactg aaagacgatg ccaacttttt
    11941 ttcggatggg ctttaaattc ttattatccg tatccggctg aatatctcgt tctccaatat
    12001 ggactgtacc gcttgttggc ttaacaagcg cattcaaatg ctgaagtaag gttgatttcc
    12061 cgcttccggt atgccctact aatgcagtat aactgttttc tttgatcgtc atattgatgt
    12121 caaataaggc tctttgttca aatggtgtat tcggctgata agtgaagtct acttgttcaa
    12181 aacggatgtc cataaccaat ccaccatcct ttcttctgtc atatattcac tgggcacatc
    12241 aaccccacgt tctttcagtg cgctcttcag tttttcagga aatggtagat ctagacctaa
    12301 gtcgatcagt tcaggaccag cagaaaaaat ttcttttggt gtaccttcac ggacaagttc
    12361 gccttgtctc atcactagta tccgattggc attagctgct tcatcaatat catgagtgat
    12421 agatataacg gtcaattgac tttcttcttt gatcttcttg atcgtagaga tcacttcttc
    12481 acgaccttct ggatctagca tactggttgc ttcatctaaa ataatgatat caggtcgtaa
    12541 ggcaaccacg ccggcaatgg caacacgttg tttttgccct cctgataaac gagcaggctc
    12601 gcgtgaagca aactcagcca ttctaacttt ctcaagtgca tctttcacac gcactagcat
    12661 ttcttctctg ggaatccctt gattttcaag accaaaagca acgtcatctt ctactgtcga
    12721 accaacaaac tgattgtctg gattttgaaa aatcattcca accatctgtc ggatcgtcca
    12781 aatattttct tcatccaata tttgatttcc cactttcacg atccctgatt ctggcagaag
    12841 caatccattg atcgttttgg caagtgtcga ttttcctgaa ccattgtgtc caataatagc
    12901 gatccactca cctttatcaa ttgtaaagga gacatctttc aatgcggggc gaagatcatc
    12961 tggctggtat ttataattta tcttttctaa ttcaataatt ggctccatga ttactccttc
    13021 ttcatcctaa agttcctact aacactatca aaaaaagaca aaattttcaa ttatttctcg
    13081 cttaaaatgt ttttttatgc cttcaaacat atctgtcatg acaggtaatt gaaggtataa
    13141 aaa
//
LOCUS       DAXQKX010000071        12478 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.073, whole genome shotgun sequence.
ACCESSION   DAXQKX010000071 DAXQKX010000000
VERSION     DAXQKX010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12478
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.073"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..338)
                     /locus_tag="ACF3MF_002322"
     CDS             complement(<1..338)
                     /locus_tag="ACF3MF_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFE3928263.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEER"
     gene            complement(335..988)
                     /locus_tag="ACF3MF_002323"
     CDS             complement(335..988)
                     /locus_tag="ACF3MF_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFE3928264.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            1276..1796
                     /locus_tag="ACF3MF_002324"
                     /pseudo
     CDS             1276..1796
                     /locus_tag="ACF3MF_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(1794..2513)
                     /locus_tag="ACF3MF_002325"
                     /pseudo
     CDS             complement(1794..2513)
                     /locus_tag="ACF3MF_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010745868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
     gene            complement(2538..2723)
                     /locus_tag="ACF3MF_002326"
     CDS             complement(2538..2723)
                     /locus_tag="ACF3MF_002326"
                     /inference="COORDINATES: protein motif:HMM:NF024811.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase-like protein"
                     /protein_id="HFE3928265.1"
                     /translation="MTKALIFDFDGTMIDSEWMFYESIHHYLLKPIYWSSSAIKFLLQ
                     TINKVLGRQQNCPFMKG"
     gene            2950..4223
                     /locus_tag="ACF3MF_002327"
                     /pseudo
     CDS             2950..4223
                     /locus_tag="ACF3MF_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(4330..5361)
                     /locus_tag="ACF3MF_002328"
     CDS             complement(4330..5361)
                     /locus_tag="ACF3MF_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3928266.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(5368..6198)
                     /locus_tag="ACF3MF_002329"
     CDS             complement(5368..6198)
                     /locus_tag="ACF3MF_002329"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFE3928267.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(6195..7010)
                     /locus_tag="ACF3MF_002330"
     CDS             complement(6195..7010)
                     /locus_tag="ACF3MF_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFE3928268.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSIVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(7007..7831)
                     /locus_tag="ACF3MF_002331"
     CDS             complement(7007..7831)
                     /locus_tag="ACF3MF_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HFE3928269.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            complement(7821..8921)
                     /locus_tag="ACF3MF_002332"
     CDS             complement(7821..8921)
                     /locus_tag="ACF3MF_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFE3928270.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            9099..9884
                     /locus_tag="ACF3MF_002333"
     CDS             9099..9884
                     /locus_tag="ACF3MF_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HFE3928271.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            9917..10300
                     /locus_tag="ACF3MF_002334"
     CDS             9917..10300
                     /locus_tag="ACF3MF_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HFE3928272.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            10376..10507
                     /locus_tag="ACF3MF_002335"
     CDS             10376..10507
                     /locus_tag="ACF3MF_002335"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: protein motif:HMM:NF012387.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFE3928273.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            10476..10712
                     /locus_tag="ACF3MF_002336"
     CDS             10476..10712
                     /locus_tag="ACF3MF_002336"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFE3928274.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            10724..10810
                     /locus_tag="ACF3MF_002337"
                     /pseudo
     CDS             10724..10810
                     /locus_tag="ACF3MF_002337"
                     /inference="COORDINATES: protein motif:HMM:NF012387.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
     gene            complement(10790..11761)
                     /locus_tag="ACF3MF_002338"
     CDS             complement(10790..11761)
                     /locus_tag="ACF3MF_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HFE3928275.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
BASE COUNT         3752 a         2796 c         2259 g         3671 t
ORIGIN      
        1 tctctttctt caattatcaa agaattacta tcactttcta aattaacatt tatattatct
       61 ttgatttgta tttcattctt attatttttt tcttttatga atacttttat ttcactactc
      121 ttggaataaa actccaaagt ttgttctata tattttattt cttttccatt catattacta
      181 gaaatttcat ttgccatatt atgaatcttt tcttttctcg tctccaaata tgttttagga
      241 aagataaaaa aaattaatga atgaactaat ataattatta ttccaagaac agaaaatatt
      301 tgtatgaaca tttttggaaa tatctttaat tttttcattt tctctccaat ttatatccta
      361 catttcttat agtagttata cagtctaatt gtaatttttt tctaagttct tttatatata
      421 catctattac tcgatcataa ggagtttctt cgctatcttt ccatacataa tcaataattt
      481 gcattcttgt taacacttgt ccattattat ccaataaaca ttttaatact tctagttctt
      541 ttgcatttac atctatttct tcaccattta ttttagctgt atagctatta aaattaaccg
      601 atagatcctt atattcaaac ttctctaaat gtccataatt cttcttaatt aaagaatcta
      661 ttctagcttt taagaccggc aatgaaaatg gcttttctac atatccgtct actaaattag
      721 taaatgcatc aattttatat tcttcatcac taaatgcagt caagattaga attggtaaat
      781 tgcttttctt tctaatttct ttcaacactt ctaaaccatt tataaaaggt atctgaatgt
      841 ctaagataac caaatttata tcgctattaa attttgacaa ggcttctctt ccatctttag
      901 cttgaataac agtatatcca aattctgaaa gatattcact tattccctct cttatcatat
      961 tatcatcttc aacagttaat attttcatat atacctccac ttaagcctat acactagata
     1021 ttatacagca tattatggct ctataatatc tagtgttggt gacgccttct gttgccaata
     1081 ctttttcttt tttttaataa atgcaaacag acaccttgaa atcctttaga aaaaaggctt
     1141 ctataatatt ttgtgttgtt ggaaaatcga aggcgatttt ctactaacac tttttcttcg
     1201 tttcaactca aaaagagact cacttttggt aaaatttagt cgaccaaaac atcaccctac
     1261 caaaggagtc gctctatgga taatcatact agaaaattac tcggattaac agataaacat
     1321 ttattttttg atgaagaatg gctgattgaa aaagaatata aaggcgttca agcgcagttt
     1381 attaaaggga gattggatga ctcaccttcc cattgtgaac actgtggatc gattcgtatt
     1441 atccgcaacg gttcctatac gacacgtact cagatgttga aagtcaaaga aaagttgact
     1501 attttagaat taaaacgtac ccgttttcta tgctatgatt gtgggcagac cttttctgcg
     1561 aaaacggact tagttgatga acatcatcaa ctaacaaagg aactgaagca ggcgattctc
     1621 atagaactgt acgaaaatca atcacgtaat ctgaaaatca gaagaagtac cgtcggctca
     1681 agcgatattg gaaactctta ctcaaagatt ccacgacatt ggagccgctc aaacggcatt
     1741 atcatcgact gtttaaacga ccaattagtc aaacagaaat cgtcgatgaa ccgttgtgca
     1801 caatggtgtc ctgaacgtac agcgacacct tccatatcca gagcagtcgc cacatcacgg
     1861 ggatggatgc catccaaatt aaaagcaacc acgccagtat gatgttcagg atcttgcggt
     1921 ccgtaaatgg tgataccgcc gatcgcttgt aatttaggta aaacgtaggc aaccagttct
     1981 tgctcataac gatgaatatt ctccatacca atctcattca agtaatcgat tgctcctgca
     2041 atgttcggag taccagcttc aaatttccat ggcagctctt tccatgaact atcgtaaaga
     2101 ttgacaaaat ctatcatttc accgccgaat tcgactggct ccatttgttc taacaattga
     2161 cgtttgccat ataatacacc gattcctgtc ggcccgcaca ttttatgccc gctaaaggcg
     2221 aaaaaatctg catccaacgc ttgtacatca actgtcatat gcggtgctgc ttgggcaccg
     2281 actggactat cctcaactac aacagcctgt tcaaccctca gccgtttcaa gcacaacaaa
     2341 taaccttctg gatctggttt gccgacctga agatcatcga tcgtcacaaa ggaatcaatt
     2401 ttttccttaa tcatcggatg tgcttcaaaa aaatagtcta gctcccgcag ttcagaattg
     2461 agactactcc gattttccag tgctgctgat ccgctgctca aaatgttcag catccactgg
     2521 tctcccaacc gcttgactta tcccttcata aaaggacagt tctgctgccg tcccaacacc
     2581 ttgttgatag tctgcaaaag gaattttata gccgaactgc tccagtaaat aggcttcagt
     2641 aaatagtgat gaatactctc gtaaaacatc cattcactgt caatcatcgt cccatcaaaa
     2701 tcaaaaataa gtgctttggt catcttcttt cccccttacc caaaacaagc aaaagctgtg
     2761 tcctgctctc tctacagtat cagcataaaa actgccgtct gaaaagtcaa aggtgaaaga
     2821 aatgtggcgc tataatttct aggactgata gtaaatcatt ctatcagtcc ttttgagcat
     2881 aaaaaaacaa aacatacaga agctccgtta gaattgaatc accacaacac aatcaaagga
     2941 gcgttctgta tgcctgatct tcatcttatc aaactattac taggaatcaa agatggaaac
     3001 attcaaatca ctcatgtcga gaagaaaaaa atacattcaa tcaacagtat cgttgtttct
     3061 gccacgctca ttaaaacgat tcagccctgt cctcagtgta aacaggtgaa tcaacatggg
     3121 ctgatcgtta agaacggaaa gaaaaaatcg ctggtccttc tcaataagtg tgcgaatcaa
     3181 cggacttatc ttgctttggc aaagcaacgg tacctctgtc gtggctgtca cacctatttt
     3241 acggcgaata cctacattgt tgaaaaaaac tgttttatcg ccaaacaagt acattataaa
     3301 atattggagg aattgactga aaaacaagca atgacgacga tttctaaaca ttgcggcgtt
     3361 tcttggtcaa ccgtttcgcg aacactcgct tctctgctcc ccatgacaaa cgtgaaaata
     3421 aattggttgc ctcgctgttc attggtagat gaatttcgtt cattgaaaaa tcaagtcggt
     3481 ccctattctt tttcttgtat ggatggcgat actgggaaat tactggatat tcttccttca
     3541 cgtaagaaga aagatctcat ttcttatttt atgcaatttg aacgacgtgc acgtttaaac
     3601 gtaaaaatac tcgtaacaga tatgaacgcc tcttatgctt tgctgataaa agagtgcttt
     3661 cctcatgcca aactcgttgt ggatcgcttt cacatcgtca agcacctcat tcgcagtttt
     3721 aaggatattt gactatgagt catgaaaagc ttcgaccgaa acgatccaat acaagccaaa
     3781 cactatcgac aagtgaaggc tttatctcga cttctgatca aacgacagga cacgcttgtt
     3841 tatgataaat ggacaaaatg gcgtaatttt ggttgggcct atttaaccga aagtgaagtc
     3901 gtagaacgtc tactttctac ttctgatgaa ctacgaatag cttatgctta ctatcaagaa
     3961 attcttcaag ctttttatga caaagaagcg gacatcttct ttcagcttgt aaaaacaatg
     4021 cccaagtcgg ttccaagaga actgcatcat ataaaaaaag cgtttataaa ctatgaatcc
     4081 ggcattcgtt tagccttaga gttgccttac tcaaatggca aaatagaaaa tctgcatacc
     4141 cacatcaaag cattgaaacg aatagcttac gggttaggat gagaaccaga attttcttaa
     4201 tcaatcatct gatcacttat taaacataaa aaaacatcta aagcagaaaa tcaattctac
     4261 cttagatgtt cttatatcac tctatcagtc ctatttgaca aagagccaga aatgtttgcc
     4321 gactatacac tagctttgtt gtgcaaaatg ctgagtatca atttccacag ggattgctag
     4381 aatatctttc agctgaatgt ataaggcatc gctaattttc tcttcccgat cgttcaaccg
     4441 atccactaaa atttctttgc cctccagcgt ttgaaaaaca taccgttgaa tgttgcctaa
     4501 aataaatgat tccttccata gaaccggaat cttaaccccc tgaggaaccg gttcaaattg
     4561 aatcagctcc ggtcttaaat aataaatgca gcgattgccc ttagcggaaa actcgtgggt
     4621 atactgattc agctcatacc attcgaaacg attatagttg ccgataaatt ccgcaacaaa
     4681 tcggctctga ggattctgat acaattcctt cgaggtggaa acctgagcca cccgcccagc
     4741 ttccatcaca aaaatccgat cactgattcg catcgcctct tcttggtcat gagtcacaaa
     4801 aatcatcgtc atccctagcg attgctggat agcgcgcaaa tcccgctgca gctgttttct
     4861 aattcgggca tccaaagcac ttaatggctc atccagcagc aggactttcg gttcagtgac
     4921 caatgagcga gccagtgcca cccgttgtcg ttgaccgcca gaaagaaact ggacattttt
     4981 atctgcctgc tccgtcatat ccaccaatga tagcatctca aaaacctttt cctgaatcac
     5041 ctcaggactc agcttcttta ccttcaaacc aaaggctaca ttttcaaaaa cagtcatagt
     5101 tggaaacaat gcatactgtt gaaaaacaaa gccgatattg cgatccttcg taggcttatc
     5161 ggcaatattc tcattgtcca gcacaatctc accgctcttt ggttgttcca atcccgtgat
     5221 acagcgcagc aacgtagact ttccgcaccc gctgggacct agtaaagtaa ccagctcacc
     5281 cttttcaatc tgaatttcat caatagctaa aatctgtttt tcatcaaaaa acagattgag
     5341 atcatgtatt tctaaaaaca ttttccgtca caactccttt aagggcttct ttttcgactg
     5401 cttctcttcc ctcgtctgct taagggacag ctgttgcttt tgtcgataag tcagcataaa
     5461 ggtagttaaa gcaattccca ccataaacag caaatacaaa accatcacag cgctagccaa
     5521 atggccgttt tcgttcatcc gccgcagcat atagatgcgt accgtctgaa atcgaccgcc
     5581 aatcaacagg ttcgtcagca tgtactcccc aaaaaccgaa gaaaaaatca tcagagaaac
     5641 tagggtcaca ccgatacgga tgtttggaaa cagcacctgg ataataatcg tagacatcgg
     5701 ggcgcccaag gtttctgctg catccactaa ttccttcaga ttaattaagc gcatctggtt
     5761 gttaagacta agatagacaa tcggcaacgc cgtaataaac aatgcaccta ccaacactac
     5821 aaacattggg ataccagttt cagcatacgt tcgaagcaaa gccgttacca aaatcactcc
     5881 tggtaaagca tacggcagca ggagcagctt ttccagccaa cgattcaaac gagggaaata
     5941 caaatgaatc caaataatgg tgggaatcat caacaacaga atcgtcacca agaccacacc
     6001 tgctaataaa agtgagcgac ccaccgcagc aataaattcc ctgtccgtca gcagctgttg
     6061 gaaccattgc aaggtaaaat cactaggtaa aagcgatttt gaccatttag tggagctggc
     6121 atacaaaatc gttccaataa tcggcagcaa gtaatacagg acaaagcaga acaaaatcgg
     6181 ttttattaac tttttcacgt ctgcaccacc ttgcctttct tttgaataat caacattgcc
     6241 gttaccagca ggacacctaa agcgactgcc aacgcactgc ctaaattagg cttggcgaac
     6301 acatctcccg acactaaagc cgcaattcga atcgttaaaa gatttacatt actgctggtc
     6361 agggcatacg ctgtttcata ggtccccatg ccattagcaa ataagatgac aaaggtgctg
     6421 gcaatcgatg gtcgcaaaaa aggcaaagcc accttgaacc aagcatacgc tgatgaagcg
     6481 cccagcaatt gtgcggactc cagccattcc tttttcactt ccttcatgct gggatacaaa
     6541 aacaagaccc ctaacggaat ttggaaatag gtatacgtga tggtcaatcc ccaccaagaa
     6601 tacaaattga agtccgctag aaatggcaaa atcattttca gcacacctac attccccaac
     6661 aaaataataa aagagaatgc cagcggaatc ccagcaaaat tagctgccaa attggaaaca
     6721 aaggtgattt tctcctgcaa tttagtcgat agattcatta agcataaaca taaaataaac
     6781 gtcccgatta acccaatcac aatggagctg acagcaatca gtacgctgtt aacaaaggcc
     6841 tgtgtgtaat atttgttgct gaaaatatca ctgtaattgg ccaatgtcca ctggttagtt
     6901 aaatcactgt gcaagctgca cagaaccata aaaagcagcg gcagcagtaa aaatgcacag
     6961 aagataaagg aggcaggaac cagaaccaag cgttttttca tctctttcat cccctcatca
     7021 attcttgaat gtcctgcatt ttctctgacg gtgcaattcc taataaccag caaaacaatg
     7081 gagccgccag cagctgtggt acagtttgtt ccttcagctt ttggcgttta tttgaaatca
     7141 aataaaaagg aacttcacga tgtgcagcca agctgccgcc atgcagtccg tgcgcatcca
     7201 tcccgtgatc cgcagtcacc acgacttgat aacctttttg cagccattca ggaaggtaaa
     7261 tagccaataa tctgtccgcc tgattaaccg ctgctgcata ttcatgagaa tcggcggtaa
     7321 atttgtgacc gacatcatca atattcatcg aatgtacgac caaaaagtct ggctgatact
     7381 gattcactaa ataatgggca tccgcaaata aatgcgaatc agggtaagtg tcctcactat
     7441 aaaagatgcc atgctgaatc agtcgctcct cctgatgctg gatgcgatca accaaacgat
     7501 tatagggggc ttgattgtac aactcgctgt accagtggta agcggcggct cctgtttttc
     7561 cgccagcttc cttaactaat tcaaacagcg accactcttt ggatcgctga gcatggtaat
     7621 tactatagat gccattttca taggctggaa cgccggtcat cagtacttcg tataacggac
     7681 gtgaattgct gggcagctca ctttttacct tcaataagct tgcttgctgg tgctcaacta
     7741 aatgattcat gaacccaagc tgggcgacgg ctgtgtcgta gcgacagccg tctagtataa
     7801 ctacaatcag tttgtcaagt ctactttgca taggtcagta cctccgcctg ccaaagctct
     7861 ggaagctcta cagaggtctt gttccaagct tcattgtctt caactggcac cgccgcttca
     7921 taagcatcct ccggcagtaa tttttcagct acttctttag gcagctctac cttgcgaata
     7981 ggtcgcgcat agccctttgc caaattgatt tgcccttcat cagataaaat atattcccgt
     8041 gctagctttg ccgcattggg atgaggggca tttttattga ttaaggttgt atacccgcta
     8101 atgatggagc cgtctgttgg cacagttacc tcaaaacgct cggagtcaat ttggtcacga
     8161 taatttagtc cattgaagtc ccaaacaact gccacatcga tttcaccttt ttcaagattt
     8221 gctacgctgg catcaacggt ggacaaacgg cctttttctg ccattttttt gtagtaattc
     8281 agacctggct gaatatcctt ttcgtcacct ccgttggcaa tcgccgcagc caatacagca
     8341 aattgtgctt ggttggcaat cgtcacatcc cccacgctaa cttgatagtc accctcttgc
     8401 agctccttcc agctagtcgg tgcttgcttc acattctctt tatcggtgat aaaggaaatg
     8461 gttcccgtat agcttaacaa ccaatcccca tcatcatcct ttgcccaatc cggaatttcc
     8521 tcccaatagt tggtcttata aggtaaggtt aactctttgc tttcagccaa cggaccgaag
     8581 ctgataccga catcaccaat atcggcggtt ccattttttc cttctgattc aaacttagcc
     8641 aattcttctg cactggacat atccgtatcc acgtgactta agccgtattc tttttcaagg
     8701 tcgttccaag tgcctaccca atttgcccaa gtatccggca ttcccaagct ggcaatctct
     8761 ccttcttcct tggctttttc tataatcgta tctaaagagt cgtctgccgc agccgattgc
     8821 ttcgttgctt cacctgagcc gcagcctgtc agcaggatac ttactgttgc tgcacaaaat
     8881 aaaccgatag tcatgttacg aattttttca ttcattttca ttcattcttc tcccctttcg
     8941 ataattccat tctaacaaag ctttgtaatg agagaatcag tttcttgaaa aggtttcatg
     9001 aacaatgtaa aggttgtata tggtttgtaa atttcgacga attcccgtta accttctaaa
     9061 gcttttgcgg tatgatagta gaaaaaagga ggctccctat gcagtattat gatcagcatc
     9121 tccacacgta tttttccttt gattcagagg aaaaatttga aaactattta gcctatcagc
     9181 cggagttttt cgtttctacg gatcactttg atttaaacaa tccatctacc ggaaaagatg
     9241 acattccgga ttatccagcc tatataaaca aactggactc tttaaaagaa acctattcca
     9301 ccaaatttct gcgaggtatc gagattggcg ttgttccagg acaagaagag cggatcgtgg
     9361 attacctcgc tcagcatcct tatgatttaa agctggtaag tattcatcaa aatggccgct
     9421 ttgattatat ggacgatgtg gttttaacca aagatcccat tcaaactacc aaggaatatt
     9481 ttgatcagat gttgcaggtc ttgacggatt ttccagaagg agatattttg actcactttg
     9541 attatggatt acgccgcttc accttcacag cggaagaatt cgcggagcat tttgaggctc
     9601 agctgctaac gattttcaaa aaggttgttg aacgagaatt ggcgatggag ttaaatgcca
     9661 agagcttctt gaaatacggc aacgaagacc tttaccgtta tgccgttcct ttgtatcaaa
     9721 gtgtcggcgg aaagctcttt accttaggct cggatgctca tgttgccgaa gattatcagc
     9781 tgggctttaa aaaaatgagt cagctgttgg cagactgtca ggtagaaaag ttgctagtca
     9841 ttcaaggaaa agaacgccgc ctgacgccgc tgccgatttt gtgattccta tataatagaa
     9901 gaaagtggtg aaaaaaatga gcaacctgtg ggactacaat caagaggcac ccatccatta
     9961 tttaattgcg cgacattggg atgcgttgaa aattgaggcg gtttgccgat ccttgttagc
    10021 agccgttcca aaacaacaac tggaaaattt tttggtggct gacagcttgc agcgggaaaa
    10081 agttcaggct tattttgcag cctttaaaga tcagcctttg gaatatttgc atgcgcagtt
    10141 tcatcttttt tatcaagtag ccgccccaga tgactacaac gatttacgag gacagctgca
    10201 attgaccttt caagcggatg aaaccgccta taccgtttta ttgggaatgg ctcgccttgg
    10261 tgatcaggcg aaggtcgagt ggcggatttt cgatatttga tggcaggatc aaggcgtttc
    10321 agttgcaaac cttcctctct ttcaattaga aaaaccgcag caggaagaag tttgtgtgct
    10381 ggtcaccgat gctggtgaaa ttcgtctccg cttatttcct gaccaagctc ccctggctgt
    10441 agccaactgg cgctccctag ctgagcaagg cgtttatgac aacacacctt tcggctcgtg
    10501 tcattaagga atttgttatt caaggtggcg ctttggatgg ttctggtgat gaagctgttt
    10561 ccagctatga gggctttttc gctgatgaag tgcatcgcgg actttatcat tttaatggcg
    10621 ccttggcctt aggggaccac ggcccccaca ccaacggcaa ccagtttttt attgtgcaaa
    10681 acacaaaggc gcaggctgac ctgctaatgt aaagcaagca tacttggagc ttggaggact
    10741 accggagctg gatggtcgtt atactgtttt tggacaggta taccaagggt tagaaatcgt
    10801 agcagcgatc gcagctcagc cgacaaacag tgaagatgta ccgattgagc cagtgttcat
    10861 tcgacaaatt aacttcgaaa aaacatcgta aaaagacact cactgacttc agcaaaagct
    10921 ctattcttga gctggctgca gctagtgagt gtctttcatt tatccataag ataaagcttg
    10981 gattcaataa ataaataaat gttttggtta aagctgtgac cagcaaatga ggaaccgtgc
    11041 gagccagttg atctgccaat gcaaacattt ctttaggtga aggcgctggc gtgtctgcca
    11101 acggatactc cagtcccaat gcttggtaac cgtgcatacc atagcagtgg tacggtagta
    11161 attctaacgg tacgaaccga tcaagatctg ccacaaaaca agcaatcgtc agcagctcgg
    11221 tcaggttcat attgatacct ggaaccacag gaactcgaat tcgcacttcg cagttaggat
    11281 actcaattaa aaagcgacga atattcttca aaatttgttg gttatctaag ccggtccatt
    11341 gtttgtggag cttgctggta aacattttta catccacaaa caatgtatcc acatagggag
    11401 ctaccttttg gatttcatta taagcaccac aaaagctggt ttccagtacg gtattgattc
    11461 caatgtattt cgatttttgc aaaatttctt tagcaaaatc cgcctgaacc agtgcctcgc
    11521 ctccgctaat ggtcactccg ccatccgagt gaaagtaaaa aacagcatcc ttctcaatct
    11581 catccattac ctcttcagcg gtcatggtct ggccaaatcc tttttcaatc tgcttgcttt
    11641 gtgattcggg aatcgaacac caggcacagc gtaatgggca gccctttaaa taaacaacgg
    11701 tccgtaaacc agcaccatca tgtagagaac cctgttctat tcttaatact gttccttcca
    11761 tatagatttt tgaattacac actagtttaa actaaaacac acaaggaaaa acttaccatt
    11821 taatcataaa attagctcat ataaatatac taggatgtaa aatagactgg tcaaaatctg
    11881 gtcaaaaaag aggactaata caggtagtcc tcttttttgt tattttaata ttctaaatca
    11941 ttttttattg gtttattccc ttattcgatg tagactcaaa tcactatatc actagatatc
    12001 aaacggcgtc atacggaatc aaaaacatca aatttgacct gttaaatggt cattgaataa
    12061 cattcaaaat caataaaacg gagtcagaca cggagtcaaa aacgctgaga gtaaaaaata
    12121 tatacagcct tgtaggtaaa gtaccacagg gctgtatatt ttttatttca gattacctta
    12181 aatgattcca tttacttttt atctcatttt ttcctactag ttagtatcaa atactctcct
    12241 attttctcaa taaactattt ttggatacat ggtatctgaa acagctaaaa ccttgtcatt
    12301 acagcaaaaa atcacgttat ccagactgta gacaaagtcc attttatgga tgatgtctac
    12361 agtcttttct tttataatag atttatgaaa acgaatgcaa ggagtgatag ctatgatgtc
    12421 taaaaacaat acgaatggta gaaatcaatt tgcgatgctt acgattgatg atctagtt
//
LOCUS       DAXQKX010000072        12040 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.074, whole genome shotgun sequence.
ACCESSION   DAXQKX010000072 DAXQKX010000000
VERSION     DAXQKX010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12040
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.074"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(59..487)
                     /locus_tag="ACF3MF_002339"
     CDS             complement(59..487)
                     /locus_tag="ACF3MF_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928276.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            complement(515..1153)
                     /locus_tag="ACF3MF_002340"
     CDS             complement(515..1153)
                     /locus_tag="ACF3MF_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3928277.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(1157..3193)
                     /locus_tag="ACF3MF_002341"
     CDS             complement(1157..3193)
                     /locus_tag="ACF3MF_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HFE3928278.1"
                     /translation="MIIKKKFTVLLTIIVTGIMSGFALVSINKQVLYRTNEFFHQTDT
                     YTPIRLPQHFIGQEEYEQLIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLE
                     MTLYYQGDVKSSHEKVPYSNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLF
                     TDRFNQAFHTDYATNIFEDFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLL
                     MNKEISLLLNNDFSLHQVLWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYV
                     FLFSGIYGISLISLLLVEKIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFS
                     SSQLAVSHEPPKEIAGEDYHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSI
                     LVNVSDYLNEENEQFGRGIKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRH
                     TDLKNDLAQITEYYQEISEKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSM
                     YLERNILSGEIYPPLKIKIGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLS
                     RSFHYLIQIFLLTFFSFFLLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNL
                     IKWGTTSVIFLFLIEREPKYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            3319..3984
                     /locus_tag="ACF3MF_002342"
     CDS             3319..3984
                     /locus_tag="ACF3MF_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3928279.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            complement(5919..9068)
                     /locus_tag="ACF3MF_002343"
     CDS             complement(5919..9068)
                     /locus_tag="ACF3MF_002343"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009035 - type I site-specific
                     deoxyribonuclease activity [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HsdR family type I site-specific
                     deoxyribonuclease"
                     /protein_id="HFE3928280.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDSQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDGVYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNEKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKTLMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSSEQINRMIDQMEPVKKESYLDPAVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQLIREGRTM
                     EDPDFPRIAITYSLEENSRDSSAQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLAIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PDKTKGLIVTFRKPATMEKNVEDATKLYSKAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSPTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYLPGEDPIPNMKAIINSKDYEGYKAKHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
     gene            complement(9081..10298)
                     /locus_tag="ACF3MF_002344"
     CDS             complement(9081..10298)
                     /locus_tag="ACF3MF_002344"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HFE3928281.1"
                     /translation="MSNDTQPEIRFPGFTDDWEQRKLGDFVVDYVEKTSVQNQFPMLT
                     SSQQKGIVLQEDYFANRQVTTENNIGYFVLPRGYFTFRSRSDNDVFVFNRNDIIDRGI
                     ISYFYPVFTLKSADSDFFLRRINNGIQRQLSIQAEGTGQHVLSLKKFKNIVAMFPSEE
                     EQQKIGTFFKQLDDTIALHQRKLDLLKETKKGFLQKMFPENGAKVPEIRFPGFTEDWE
                     ERKLGELGKTQSGIGFPDAEQGGSEGTPFFKVSDMNNIGNEYEMRNANHYVSNEQIER
                     KKWKPIKDVPAIIFAKVGAAIMLNRKRLVTSPFLIDNNTMAYLFNNTWDIYFGKILFE
                     TINLPRYSQVGALPSYNSSDIENISVKVPVKDEQQKIGTFFKQLDDTIALHQRKLDLL
                     KETKKSFLQKMFV"
     gene            complement(10288..11883)
                     /locus_tag="ACF3MF_002345"
     CDS             complement(10288..11883)
                     /locus_tag="ACF3MF_002345"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HFE3928282.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAIAPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVDVLEHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLATFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKKLLEAIS
                     SLQTTPENEAWLQGALEVFKHEQ"
BASE COUNT         3678 a         2345 c         1908 g         4109 t
ORIGIN      
        1 taacttttaa cgctgtttca ttatatgttt tttctatttt atataaactt ttggatactt
       61 aataccaacc ggttggattg taccaacatg agaatgtgtc agttctattt cctgtcgcac
      121 ttgcataggc ccatactcct tttgttgcat ttgctgatcg aatagagttt ccaactttcg
      181 cttttgcacc gtgacgatta tagacacgac tatagtggtt agaatgacct gtttttctcg
      241 tacaagttgt atcactataa taaacccatc ttccagagct atgattaatt gctgttctag
      301 aaatttcccg gtctactggt aaatttgact taataatatt acctttagca tcaaaatgaa
      361 tctctcctgg ctttaaagat ttgtaataga tttcaccgtg aactgaattt gcttccactt
      421 cagatgacat agcgtttcct ccaacaaaac ctatccctag tgcacaaata ataactgctt
      481 ttttcataaa acgacatcct ttcctttttg atttttaaag catgatcttc ttgtttccta
      541 ttttggtcag atatggatca tgcgtgacta cgataactaa cgtaccttgg gaagcttgtt
      601 gcgataagat ttcaactact ttatccttat ttcttttatc caatgaccca gtcggttcat
      661 cggctaaaat gattttgcta ttcttcaata agactctcgc acaggcgatt ctttgcttct
      721 caccaccaga taatgtgtag ataggcgtac ttagcttctt gtttatattt acttttttca
      781 atgcctcata ctttgctgtt cgcttatctg aaacatttaa attcgaaaac ttcaatccaa
      841 tatctaaatt aaaatcgatt gtttcatatt caatcaaccc aaaatcttga aaaagaaaag
      901 atatggtatt tctttttatc aagcgcttct ctctcccagt taattgtttc gtctcttgat
      961 cgaacaaata gaattgtcct gaactgaact gatcattcaa tcctaatata ttcaataacg
     1021 tacttttacc tgctccactt tctccaacaa cagtcacaag atccccagca tccgcagtga
     1081 aacgatccaa atgaagaatc gttttgtttc gaatgatttt tttcgcacct tttatcacta
     1141 tcaacggctc caattgttaa cctccattca tcagcaataa ctgacttttc ttttctgtag
     1201 acaaaataaa aacaactgaa agaataaaat caatgaagct aaagaaaaaa atattaaaaa
     1261 gatatttagg ctctctttct ataagaaaaa ggaagattac acttgtcgtt ccccatttga
     1321 tgaggttcat catgaagaaa tctttatacg tttcaaagag cgaataacca cttgaacgaa
     1381 agatagcgat tttccgacaa ttgtagacaa aatatatgca taacatgaca tagctcaaca
     1441 agaagaaaga aaagaaagtg agtaaaaata tctgtatcaa gtaatgaaat gatctgctta
     1501 acactttgac agctatctct tcagtctgag tatacggaaa tgataactgc aagttatcac
     1561 gtaactgact ttcttcaatc agctcaaata acctttcttt cgacaaagag cctatcttga
     1621 tctttaacgg tggatagatt tctccgctga gaatatttct ttccaaatac atactgtttt
     1681 tcaatgtcag tatttcaaca accggataat gttcgatcca ggggatagaa ggaataaatg
     1741 tataaatggg ttgattgttt tttataaata gaaatttcgg ttctttttca ctgatttctt
     1801 gataatattc tgttatttgc gccaggtcat tttttaaatc tgtatgtcta tatcgttcag
     1861 ggatcaatat aacagggtgc gtttcttttt cggttatttg gatcaacctt ccagagacat
     1921 caatcaaagg aaatttctta agataattca gatttatttt tatccctctg ccaaactgtt
     1981 cattttcttc attcaagtaa tctgatacat tgactaatat acttccgttt ttattcaaag
     2041 tttcatataa ttcctgatct gctgctgatg caaaacgatt ggaataaata aaatccacgt
     2101 ggtttttccc gatggttact ggataaaata catgatagtc ctcaccagcg atttcttttg
     2161 gtggttcatg ggaaacagct aactgtgaag aagaaaaaac gatagttgct aattcgacat
     2221 tggcaacggt caaaagaaga gaaaacaaca atccaaatgt aaaaagaatg tattggatat
     2281 agttgaacgc ttctcttaac gaagcgattt tttcaactaa taaaagagaa atcaaagaga
     2341 taccatatat tccgctgaac aagaaaacgt acatctggaa caaataaaga aattgctcct
     2401 tataatacat aaaaataaaa ccaccaatga ttcctgcaat tatgaatgta ataatgattt
     2461 tctttttccc caataaacac cacaatactt gatgtaatga aaagtcatta ttcaacaata
     2521 aactgatttc tttattcatc aataagaaaa aggatgataa caaaaggaat aaaagaatca
     2581 atccaatagt taaatacact cgataattat atacgtctgt atttgaaata accgaatacg
     2641 aatagctatt ttcaaagtct tcaaaaatat tagtggcata atcagtgtga aatgcttgat
     2701 tgaatcgatc agtgaatagt gaaatgaacc gttcataggc ttctttttct ctcgtcatca
     2761 agaaaaattc accttcaaaa tcttttattt tgatcgattc ttcaatggac gttacgcgaa
     2821 aggaggtatt agaatagggt accttctcgt gagaagattt gacatcccct tgataataca
     2881 atgtcatttc aagctttggc tgtatcttga agttccaaga tgtatctact tcattggatt
     2941 catttactgt ttttttcata taagaaagct cagtttctga tgagacattt tcaaatacca
     3001 tgattagctg ctcatattct tcttgcccaa taaaatgttg tggcaatcga atcggagtat
     3061 aagtatctgt ttgatggaaa aattcatttg tccgatagag tacctgttta tttatactaa
     3121 ccaaggcaaa accactcatg ataccggtca ctatgattgt gagtaaaact gtgaactttt
     3181 ttttgattat caccactctc ccttacttaa atgattcttt gataaaatca taccgttttt
     3241 catcaaaaaa acgtatctat caagtgtata ggtcatgtag aataaatcta tatactgtag
     3301 aatcgaaagg agaagaagat gaacaccgga gaaaaaatac gaacttaccg cagaaattgt
     3361 aagcttacgc aaaaagaatt aggcgaaaaa attggtgttt ccgataaaac gatttctagt
     3421 tgggaaaatt ctcgtacaat gccagacctt gaaatgctgt cacttttaca tcatacttta
     3481 ggtctgccga ttgattttcc ttctattgaa tcagctaccg aatcaataga accaacattg
     3541 ccagatgaac ctcttgttaa caagaaatct tattcatcaa aacaaccctt ctcactcaaa
     3601 aagacactat ctttctttct gctcgtcttt tgtttggtct atctttttct tatcaattat
     3661 caatacaaaa atgaaacgat cgatcgattc aatccttttt tgaaaccaca aatcggctat
     3721 accacactcc ctgtaggata cgtggacaat tccatcgaac gttgggtatg taatgatatc
     3781 tttggccatg gtacatggct gtcttttcac gctggagagg tagaaaaaga gaaaaaccat
     3841 gctgtaatca aacacaaagg aaaacacgtc atgaacgttc gcctgctcac ttgggaagcc
     3901 attccctcag attaccaaga aatcctcagc caagactatg acgacgcctt aaaaagaagc
     3961 cctcaggagc cagataggca ttaagtagga gatgaacgta gagatagaaa aaatcaatgc
     4021 acatgatctt atccaaaaaa caggggtaca aattaattga aaaagccttg agatgaaagt
     4081 tcctaaataa aaaagttcag aatgataggt atttctggct tatagtataa tatttacgcc
     4141 acagcctccc aatgattctt tttggaatca taatcaagga tggacattca caaaaatatt
     4201 ttgctcattc gatccgaata gattaacgac caatctagta agtaatatag attggtacgt
     4261 agtcaagctg cacataattt agatcaattt tagttctttt ttatatttct atgatctgct
     4321 catttacttt tatatgatgg cttacagtaa cataaataaa tatgataatc gctggtagtt
     4381 tatccaagag tactcaataa aatacaaaat ggattgttca agcgcctatc ataatgataa
     4441 aatgaaacaa ataaacgata caaggaggaa gagactttga gtaatggcag aacaattttt
     4501 tcattgtaaa aattgttcag ttgttaatct atgggatttc ggtagcatgg gcattttttt
     4561 atagaggaat cacaccaacc tggccgtttt atctcttgtt agtgggaata ttagtaggaa
     4621 attttgcccc tcttcactat cgtacgaact tttttccaac tgattctggc ctttttctta
     4681 aaacaaagac gcgaaaatta gaaaacatta ttgaaatgac aattacctgt ataatcattt
     4741 tcttagttat attcctaaac gtcttctaat aagaatctct taaaattagc ttgttacagt
     4801 tagttaccta gtttatataa cacagttatc ttatcttcct tatcaacatc ttttgccaac
     4861 tctttgtctt aaattcgaaa catataagca gagctacgaa caccaagact gtttcggctc
     4921 tgttttttgc atcaaattca ctcttatata gctgataatc tcggctcttt aaaagaaatt
     4981 attttcgctt cattttatta taaaaaggct aggaaccttg atgttatcag gttcctagcc
     5041 tttatttaag tattacccca cagacccttc catatagatt tttaaattac acactagttt
     5101 aaactaaaac aaacaaggaa aaacttacca tttaatcaaa aaattagctc atatgaatat
     5161 attagaatgt aaattagact ggtcaaaatc tggtcaaaaa agaggacgaa tacaggtagt
     5221 cctctttttt gttattttga tattctaaat cattttttat tggattattc ccttgttcga
     5281 tatagaccca aattgatcta tcaataatta tcaaactgag tcatatagag acaaaaattt
     5341 caaaaatgac ctgttaaatg gtcatcgaat atcatttaaa atcaatacga cggagtcaga
     5401 cacggagtca aaacaagccc gctgagagta aaaaatatac agtcccatag gtaaagtgcc
     5461 acaggactgt atattttttt atttgagatt acctgaaatg attccattta atttttatct
     5521 cattttttcc tactagttag tatcaaatac tctcctattt tctcaataaa ctattttggg
     5581 ttacatggta tctgaaacag ctaaaacctt gtcattatag caaaaaatca ctttatctcc
     5641 gtttcatttc agatacattt cacttaagcg gattccaaaa aaacaaaaga aaaaggaacc
     5701 cctagttagc ctatgctttt tattggttcc tctcaaaaca cggtcatata acaacggggt
     5761 ggggtaaatg aatgaaaaag gtggaggaaa cattattcaa tagctgtctt aaatacttcg
     5821 ttataaaatg tgaacaaata aaagacatct atccctattt tctacacttc cacttgacta
     5881 ccatctttga atcgtacaat tttcttaact cttctcgttt acctcaattc attctcaagt
     5941 ggaatcaact catcatctaa cattttacgc catgctcgct tcatttcttg tgggtattta
     6001 aatggcttcg cttctggatg tttggcttta tatccttcgt aatccttact gttgataatt
     6061 gctttcatat taggaattgg atcttcacct ggtagatatt gcagattaga agcatgtaat
     6121 tctttctcag aaacaaacca ctcattggaa aagacatgaa tcaaatcatc actcgcttgt
     6181 gtaaaatagc gacgtttaat gacaaagata tcttcattac tatctaaagt ccccacatca
     6241 aatgcattta aaatttgtcg gtaaacttct ttgactcctt ctgttttatt caatttagcc
     6301 aaagcttttt caatttcttc tcgtgcatct gaactattcg cagcataagt tcctagtaat
     6361 tgatcaatat aagttgaatc aatatcatac aacttagtgg tattttcact ataaaattcg
     6421 atcgttgaaa aatcttctcc ttctttttct ggttcttcct ctattaatga acccttcacg
     6481 gtctcgtaca cgccaatttg ttcttccaaa agttgaattt gattgttcaa agttggagat
     6541 ttcaccatgt catcattgta atcgtcataa gtcactaacg attcataagc acgattcaat
     6601 tcttgaaatg ctttgacgta ctcgatacgg atttcaagtg gcgtatgttc atcaatggat
     6661 tccatggatg aaacctcttt taacttacca tatgcttgtt tgaatctttt tttggattcc
     6721 tgataacttg gataaatcaa acctgattct tcttttgctt ttgaatacag ttttgtcgca
     6781 tcctcgacat tcttctccat tgtcgctggc ttacgaaacg tcacaatcaa tccttttgtc
     6841 ttatcaggat acgtacgatt cgtacgtgaa aaagcttgga tcaatcctgc atactctaga
     6901 ttacgatcca caaatagggt ttgaatcgta ggggcgtcaa aacctgttaa tagacgatcc
     6961 actacaatcg ctaaatcgat ttgtttccca aattgtttga attccgctct ttttcgtgcc
     7021 aaacgattat tgatgtctcc gttataacgc tcaatgtctg ctaatgacca ggaagtatca
     7081 taatactgat tatattcctc aataattttt tgcatttctt cttgttgggc acttgaatct
     7141 cggctatttt cttctaatga ataggtaata gcgattcgtg gaaaatcagg atcctccatc
     7201 gttcgtcctt cacgaatgag ctgattggga aactcttttg ttaaccaatc aggctctttc
     7261 gtcatctctt tgatggcccg ataatacttt ttggccatgt caatggaact cgtggttaag
     7321 attgcagatt tcgttggcct gccatttcga aaatcaaatt ttgtataggc attatctgga
     7381 cggaacattt tatgaatgac tttttggata tgttcatctg cttcaaaaac agctgggtcc
     7441 aaataacttt cttttttgac aggttccatt tgatcaatca tacgattgat ctgttctgat
     7501 gaatactctg catatgtttc tacttctttt aatttccgat agattttatt ctctagtgaa
     7561 gtcggctcca cggtgttttc atgctctact tgaaatccta agacagagcc atcttctagc
     7621 gcattcttaa tggtataggt atgcaagacc tctccatact gatcatgggt tgtacgtgcc
     7681 aattgccctt tggcttgttt ccgattctca ggaaaaatcg gtgtacctgt aaagccaaac
     7741 caagtggatt tcggaaacat ttttttgatt tcttccatat tttcagcact taacgctcga
     7801 tgacactcat ctactacaaa cacgatatgt tggcccatta atttttggaa gcgattggtt
     7861 ccttttttct cttcttgttt ctttgcatat ttcaacgccg catctagttt ttgacgggtt
     7921 gtaatgatta caacatttgc attggcatct gccaacaggg tttcacttaa ttctttggca
     7981 cttcccgttc caacgatcaa gctattcgct ttggcgttcc cggaagaaat cccagtatta
     8041 aattccgaag caaattttgt aaactctgtg gtggtttgat tatctaaatc tttgcggtcc
     8101 actaacatga tcgttcgatc gatccccgat tttcgtgcta aaagcttagt agatacaaaa
     8161 ctagtcaacg tctttcctga accagtcgca tgccacacat accctgattg atgtttattt
     8221 gcggcaataa acaaggcttg aatcgcatgt acttgataag gatgtaacac catgagggtt
     8281 ttattgtctt gatcttcact gacgattgta taatccgcaa tcaaacgatg agcatccggg
     8341 atatttaaca cttgtttaca aaactcatat aagttttcta ctttttcatt gtctttcgtt
     8401 cgccaactaa ataaaaactt agggtgcaag tctttcggta aggcatttgc aaaataccga
     8461 gtggtttgtt cattggaaac cacaaacaac tgtaaggtcg aaaagatatt gttccgaaac
     8521 ataccttctt ctgcatattt tttgatttgg ttaaatgcct gataaacacc atcttttgca
     8581 gttacttgtt tcagctcgat ttggacaatc ggtaatccat tgattaataa ggtgacgtca
     8641 aaacgtcgat cccgtgcttc tatgttactt ccacgttttg caatttgatg gaccacttca
     8701 taagtagaga ttcctccacc aatgtcttga ttggaataaa ggataagtga gacagaaccc
     8761 aattgcgaat cttcccgttc aatcgtgatc cgagccatcc cattttcacc ttttaaccat
     8821 ttcgcagcat caaatggggt tttcgttcgc agcagtaatt ccgttttgat cgtttcaaat
     8881 tctttatcgg tcaaaggaaa atcattcagt tctgcttgat tatttgagat aattttttgg
     8941 cgtaaattga cccaaaggtc ttcttctgat tttagatccg gacgatacgt ccactgatta
     9001 tgcccttctc caagtacacg aatcaactgt tcttcgactt ctgcttcctc acggtgacta
     9061 attttcattc ttcttccctc ctagacaaac atcttttgta agaagctttt tttcgtttct
     9121 tttagtaaat ctaacttacg ttgatgaaga gcgatcgtat catctagctg tttgaagaaa
     9181 gtaccgattt tttgttgttc atcctttaca ggaaccttaa cactgatatt ctcaatatca
     9241 gaactgttat aagaaggcaa tgcccctact tgggagtatc ttggcaaatt tatagtttca
     9301 aacaatattt taccaaaata gatatcccaa gtattattaa ataaataagc catggtattg
     9361 ttatctatta agaaagggct tgtgaccaaa cgttttctat taagcattat tgctgcgcca
     9421 actttagcaa atataatcgc tggcacatct tttattggct tccatttttt acgctcaatt
     9481 tgctcattag atacataatg atttgcattt ctcatttcat actcattacc aatgttattc
     9541 atgtcggaaa ctttaaaaaa tggagtacct tcagaaccac cttgctcggc atcaggaaat
     9601 ccaattcccg attgagtttt acctaattct cccaacttac gctcttccca atcttccgta
     9661 aaaccaggaa accggatttc tggcactttt gctccgtttt cagggaacat tttttgtaag
     9721 aatccttttt tcgtttcctt cagcaaatct aacttacgct gatgaagagc gatcgtgtcg
     9781 tcaagttgtt tgaagaaggt gccgattttt tgttgttctt cctcactagg aaacattgct
     9841 actatatttt taaacttttt tagagacaga acatgttgac ctgttccctc tgcttgaata
     9901 gataattgtc gttggattcc attgttaata cgtcttaaga agaagtcgga atcagcagat
     9961 tttaaagtaa atacaggata aaaatagctt ataatccctc tatcaataat gtcattacgg
    10021 ttaaacacaa acacatcatt atcacttcga ctacggaacg tgaaatatcc tctaggtagt
    10081 acaaagtaac caatattatt ttctgtagtt acttgccgat ttgcaaaata gtcttcttgc
    10141 aaaactatcc ctttttgttg agatgaagtt agcataggaa attgattttg tacacttgtc
    10201 ttttcaacat aatctacaac gaagtccccc aacttcctct gttcccaatc atctgtaaat
    10261 cctgggaaac ggatttctgg ttgtgtatca ttgctcatgt ttgaacacct ccagcgcacc
    10321 ttgtaaccac gcttcatttt caggtgttgt ttgcagggaa gagatagctt ctaaaagttt
    10381 tttttctagc acttgctgtt cttgtcgtat cttcttgatg tcatttccga catgaaccat
    10441 atcaattggt tcttcttctt cgaaagtatc tacatagcgt gggatattta agttatagtc
    10501 attttctttg atttcatcaa aggttgccaa atgagcgtat ttctcgacat cttttctttc
    10561 agcgtaggtt tcgaggattt tttgaatgtt ttcttccgat agtttatttt gatttttccc
    10621 tttaacaaat tcacgactag catcaatgaa taatacatct cgagtttgac gattcttctt
    10681 caacacaatc accgtcgttg gaatcgatgt cccaaagaac aagttcgcag gcataccgat
    10741 cacagcataa atactgccat cttctagtaa tttttgacgg atgacccctt ctgcagcgcc
    10801 acggaataaa actccgtgtg gtaagacgat ggccatggta cctgtttcct tcaaatgata
    10861 gaacccatga agaagaaacg caaaatctgc tttggatttt ggcgctaatt tcccataacg
    10921 attaaaccga gaatcatcta agaaagtcgt atctgctgac caattagccg aataaggtgg
    10981 gttcattact actgcatcaa atgtgtaagg ttcatctgtt ggccagtcct tattcaacgt
    11041 atccccattg cggagattca tttcttcggc gtcgacacca tgtaaaatca agttcatttt
    11101 tgctagattg tatgtcgttg tatttagttc ttgcccatga tatttaacgt tatctgggtg
    11161 tgttaagtag ttacgtacgt ttaacatcaa tgaacctgaa cccatcgttg gatcaaaaac
    11221 actaaagaat cgtcgttcct tttgatcgag cgttacgatt tgcgccatca tatcagaaac
    11281 catatgaggt gtgtaaaatt ctccggcttt cttccctgct tctgaagcaa attgactgat
    11341 cagaaactca tacgcatccc cgatcacgtc cccatcgtgt tctaaaacat ctacatcatt
    11401 caatttcttg atgacttcgg taatcgtcac atttcgttgt tgctcatctg ttcctagttt
    11461 ttttgattgg agatccacat catcaaataa cccattaaat tgattgtagg tagatgccaa
    11521 ttgcacaaag gctttgttta gatcgttcaa ttggaacgtt gcttgttttg cttgatccgc
    11581 taagacgttg aaaagatact ctggtgcaat tgcatatccc aaaatatcaa cgattgtggc
    11641 aatcagatct tcttttgatt cttcatctga aagtaattca cgatacaaca ttgtttgttt
    11701 gcttactgtg tcatattcct ctaaggattc atctgctaaa agaaccactt gttccaacaa
    11761 tcgatcggat aaatatttat agaaaatcag tcccaataaa taatttttat attctgacgc
    11821 atccatttta ctacggagat tatctgccgc actaaataat ttttgattta attctgcacc
    11881 caaaaagata cactcctatc tcttatttaa agttgctata taccctctta ttttagcata
    11941 ccccctttta taaaaagcaa aaaaaaaaag aaagaaactt attcttgcta ataaactacg
    12001 cgaaaggagt ctaacgttgt ttgatataac ttagactgat
//
LOCUS       DAXQKX010000073        11718 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.075, whole genome shotgun sequence.
ACCESSION   DAXQKX010000073 DAXQKX010000000
VERSION     DAXQKX010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11718
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.075"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            127..3654
                     /locus_tag="ACF3MF_002346"
     CDS             127..3654
                     /locus_tag="ACF3MF_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HFE3928283.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3651..7373
                     /gene="addA"
                     /locus_tag="ACF3MF_002347"
     CDS             3651..7373
                     /gene="addA"
                     /locus_tag="ACF3MF_002347"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HFE3928284.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7442..7783
                     /locus_tag="ACF3MF_002348"
     CDS             7442..7783
                     /locus_tag="ACF3MF_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFE3928285.1"
                     /translation="MELTQTEFVLCPKFEKSFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8092..9135
                     /gene="pheS"
                     /locus_tag="ACF3MF_002349"
     CDS             8092..9135
                     /gene="pheS"
                     /locus_tag="ACF3MF_002349"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HFE3928286.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9140..11560
                     /gene="pheT"
                     /locus_tag="ACF3MF_002350"
     CDS             9140..11560
                     /gene="pheT"
                     /locus_tag="ACF3MF_002350"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HFE3928287.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGVVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
BASE COUNT         4044 a         2003 c         2515 g         3156 t
ORIGIN      
        1 cgtatactta aaaaagtaga aatatcagaa ccttaaaagg atataatttg aagaatatag
       61 aacaaatgtt cagtattttt tgatataata aaggagcacc gtatcatgtg ttgaaggagg
      121 aaaagcatgt ctttacaatt tattcttgga aacgggaaaa aagatcaccg tcaagtcttg
      181 atcgacgaag catccgcttg gctcgaccag gatgcaagta accaagtatt tttccttgtt
      241 cccaactaca gcaaattcga acaggaacaa gaaattttag cggagatgcg aagaagaagc
      301 ggaaaaaaaa ctttcagcac aacaaacgtt caagtattta gtttttatcg tctggcttgg
      361 tatttgctgc aacagacaac tcttcttaca ggaaatgaat tatcagaatc aggatctgca
      421 atgatcttgc gacagatttt agaaaaaaat gaggaagaat taacaatctt tcgcggagaa
      481 atcaataaaa gagggtttat tcgtcaatta caagaactct acagtgaatt gcgtacagga
      541 aatattcaac cagaagacct gatgctttta tttggtgatt cacctaatgc agaagaccag
      601 caacttaaaa tgaaagactt gaagctgatt ttttcagctt atgacagcga attgactcaa
      661 cgtgcactaa caaatgaaga tgcactatct atactagcaa attatatgca gacacaagat
      721 ttcaacaacg tcaaatttat tgtcagtggt ttttctcgaa tcaatggtca agagtatcaa
      781 ttactgcagg caatgatgga aaaggggcaa ttggttgtcg atttattgct ggatcgtcct
      841 tatacagcgg atcttccaga agtacttacg ctctttcatg agactggaaa gctttatttc
      901 cgtctttttc aaagtgcaag agaacggaaa gtccctatat tagtggaccg atttgcacca
      961 gagcagactc gtccgacaga gcttcaactg ctgcaaacaa tgtgggaaga gacatctagc
     1021 caaaagaaag cggcagtaca caaaataggg ggacaagagc atctccattt gtgggaagct
     1081 gaaaatccaa ctgaagaagt ccgacaatta gctgttgaaa tcagacgact agtcagtgaa
     1141 gaaaactacc gttatcgtga tatccaagtg ctgacaaaaa atatgtcttt atatggaaat
     1201 atccttcggc cgatctttca agaaatggca attccttttt atatcgatga agaacaaatg
     1261 atggaaaatc atccgctgat cgaatggatc aacagtctgt tcgctcttga ccgctattct
     1321 tatcggctaa gtgatattat gcgttttttc aaaactgaat tatttctgtc gacggaagca
     1381 gaaaccgaac ttgatgaatg gaaacaagag cgagatgaat tcaggaaaaa actggacatc
     1441 actgaaaatg tagcacttgc ttacaattat caaggaactt attggactcg tgaaaaagac
     1501 tggcagtttg tggcgtatga ttttgaagca gaacagattg aagacgtaca gtatttggaa
     1561 gaacagtcaa atacgattag acgattattt cagaaagctg taccagtatt tttgaaaaaa
     1621 ataaagaaaa gcaaaacagg acaagaggcc gcaaatgttt tttatcaatt tttgatccaa
     1681 agtggcgtac agcaacaatt attgttttgg cgtaatcagg aagtagacag aggaaactta
     1741 gaagcggcaa gaaaccatga gcagacatgg ggagcgctga ttgatctgtt ggatgaatat
     1801 gtagtaattt atggtgaatc ggcttttgac tggtcactgt tccaagaaat cattacaagt
     1861 ggtctagaaa atctaagtta tggtaaaatc cctaccgcaa tcgaccaagt gcgaatcaat
     1921 cgtttggaat tagttcgacc aaatcaagct gccgtcactt ttgcattagg gttgaatgat
     1981 caagtgtttc cagaccgaaa agagacaaaa ggattgttgt ccagtgaaga acgagaagta
     2041 ttaaatcagg ccttgccaga tggacagttt ttattcgacc catcaaagga aagtatctct
     2101 tttgagcctt tccaagccta tcttgttttt ctttccggaa cagatcgatt atatcttagt
     2161 tatgcacaaa gctatgacac agatggttcg ctgaagatgt ctccttattt gcgtagaatc
     2221 acagaatatt tatctgttcc cgtcgagaga aaagagcatt tgacgatcga aagcgaccct
     2281 aattgttatg tagggactta cagaagcgga atcaatacag tcaataggat ttatcgatta
     2341 gctttagatg aaaaaaaacc tgtaccaaag cactggcaaa agctcaaaga attagtactg
     2401 aattcgtcat ggcgaaattt tgctttacag atttttgaaa gtcaggaaca tttaaatgtt
     2461 cctgtttcga tgccagaaaa aatggcggaa gagctttatg gaaaagagat ttatacttca
     2521 atttcacgta tggagaattt ttataattgt gaatacaaat acttcatgca atttggtttg
     2581 aaattgaaag aacgaactgt ttatggtcta actccagcag caactggtga tttttatcat
     2641 gaatcattgg atcgtttctt caagctactg ttttcaaacc aattatcctt agtgaatatg
     2701 tccgatgcgc agcgtagaga ctttactgaa aaagtgctgc aggaagtatt cggagaactt
     2761 cggtttgaga tattggatag ttctgcaaga atgaactata tccgctacca gttaggacag
     2821 acgattcaaa aagtgacatg ggctttgcaa aaacagagca aaaatacagg catgcatcct
     2881 cttcagacag agattctatt tggtcagatt gctggagcaa aaggtatcac aggtctggaa
     2941 ttaccgttga gtaatggtgg aaaactccat gttcgaggga aaatcgatcg aatcgatgta
     3001 gcttctgaac aagaagatac ttggctaagc gtcgttgatt acaaatctag cggacgttca
     3061 ttcgatgtca cagaagctta ttatggcatg gctatgcaat tattgacgta tctggacgta
     3121 gcattgatgg atgcggtacg tttgactgga aaggcggctg ttaaaccagc aggatcatat
     3181 tatttacatg ttcataatcc tgtattgacg gagacagatg atgtagagaa gaatacattg
     3241 aaaaaattta gttatgatgg cgtttttgtc gatgatcccg ctcttttaga agtactagat
     3301 cattcactgg aagcaaaaga acaatcactg atctatccag tgaaaaaaaa tgcgaaagat
     3361 gaataccaaa aaggtagttt cagtaaagac aaatttttca cggaagaaga actgcaacta
     3421 ttcatggcgc ataatcggga aaatatgcgg ttagctggag atgcgattac ttccggagaa
     3481 atcaaactaa atccagctta taaagataaa cagcggattg cctgcgaatt ttgtccattc
     3541 agaagcatct gtacgtttga tgtgatgctg aaagaaaata attaccaccg tctggagaaa
     3601 atagataagg aagaagcact gcgtagaata ttgaaaagga gtgaagaaga gtgaatcaaa
     3661 ttcctttaaa accgcaaaat gaacgattca cagatgatca gtggcaagcg atttttgatc
     3721 aaggagataa tctattagtc tctgcgtctg ccggatcagg taaaactaca gtgcttgttc
     3781 gaagagtgat tgaaaaacta aaaatgggtt ttgatatcga tgaattattg attgtgacat
     3841 ttactgaagc tgccgcaaga gaaatgaaag aaagaattca agaggcatta caagaatccg
     3901 tcaatagcga aagtgaccct gtacgtagac agcattttac taagcagtta gttttattgc
     3961 ccacagcgaa tatctcaacc ttacatgctt tttgcctgac agttattcga cgttattatt
     4021 acttaattga tattgatcca gtctttcgca tgttaacaga tgaaacagaa acgatcttga
     4081 tgaaggagga tgtgtgggac gagctgagag aagcacttta tgcagaaaat gatgaacgat
     4141 ttttccaatt aacaatgaat ttttctaatg atcgttcaga tgacggcttg acgaatctgg
     4201 tgttttctct ttatgagttt gcccgtgcca accctgaccc ccaaaaatgg ctagaacagt
     4261 taagcgataa ttatcgtttg cctgaggggc tagcgaaatc tcgattatat caaaaacaaa
     4321 tccgtccttt agttttggca gatatatacc aatgtgtaca gttatatgaa cagatgactc
     4381 agttagcaca aggtgaagga ttagaaaaaa tgcatgagca agtagctgga gaacaacagc
     4441 agatcaagaa tatctatgaa gcgttctcgc aagatcggtt agaagaagct tatgctggtt
     4501 tggaacaact aactttttca acttttaaga gcagtcggaa agcagaattg aaagaaattt
     4561 ccaatgaagt caagggcatg agggataaag caaaaaaact gattcagcag ataagtaaaa
     4621 gttattttcc tgtttcccca agccaaatgg aagaattaac ggacaaagca ctaccgttag
     4681 tcgaagaaat gacaaaagtc acgcaaagct tcatggacgg tttcagtatg cgtaaacggg
     4741 aaaaaggtgt gctggatttc aatgatctgg aacatttagc gttgcagatt ctcacagaaa
     4801 aaacgaaaga tgtatggctg ccaagtgaag cttcaaaaca ttatcgaaaa aaattcaaag
     4861 aagtaatggt agatgaatat caagacgtga accaattaca agaagccatt ttatactggc
     4921 taagagaacc cgatgataca aaaggaaata tgttcatggt tggggatgtc aaacaatcca
     4981 tctattcttt ccgtttagca gatcctagtt tatttatcgg gaaatacgag aatttctcaa
     5041 agaaagaagg cggacgtcga atcgttttgg ctgagaactt ccgctctaga aaagaagtcc
     5101 tttcttttac gaatcttatt tttgaacaac taatggatcc agcagtgggt caaatcaatt
     5161 atgacgaagc agccaaactg atccaaggat tttcagactt tccagagaat gaacagtttg
     5221 agccggaaat catgatctat gaaaaagaac aggaagaatc agagattgag attccgacgg
     5281 atgatatact ggaagacaaa acagaaggcg aactttttat gacaggacta aaaattcgtc
     5341 aattaattga ttcctccttt atgatttatg ataaaaaatc aaaaaaaagt cgtccgatag
     5401 agtacaaaga cattgttctc ttgacaccta caaagaagaa caacttaacg attttagaga
     5461 ttttcaaaac attggatatt ccattagaga tgaatgatgc tcaaaactat tttcaagcga
     5521 cagaaattcg cacgatgatc tcgctgctac aattaatcga taatccctat caagatattc
     5581 cgcttgcggc tgtattgcgc tcaccgatcg tgggtctgat tgaaccagaa ttagccagca
     5641 ttcgattagc taaccgtgca catacttact atgatgctgt gcttgcttat caagcatcaa
     5701 acgaagatga attagcagct aagctggaac attttggcaa gcaactagag cattggcgag
     5761 aacttgctcg ccgttcttcg atcactgact tgttatggga tatctattat gagacgggat
     5821 atctagagta tgtggtcggt ctgccagcag gggcacagag acaagccaat ctttatgcat
     5881 tggttgatcg tgccaaagct tacgagcaaa gttctttcag aggattatac cagttcgtgc
     5941 gtttcattga aaaaatgcaa gaaaaagata aagacttagc agaaccagtc atttcaatag
     6001 aagataatgc tgttcgcgtt atgacgatcc atgcaagtaa aggcttggaa ttcccagttg
     6061 tatttttgtt agatatgaca aaggagttca acttacaaga cttgcgcaat cggtatgctt
     6121 ttgaagaaaa acttggagca ggaattcgct atatggatcc tgaaacacga gtgttatatg
     6181 atacgttacc gtttcaagcc atcaaattgg caaagcaaaa caaattgttg tcggaagaaa
     6241 tgcgtaaatt gtatgtagga ttgactcggg cagaacaaaa gcttttcatt gtcggttcct
     6301 ataaaaataa agagcaaatg atccaaacgt ggtctgaagc agctgatcat gaggagttag
     6361 tttttgatcc tgcgctacgt ttgaagggca gaagcagctt gatgaattgg attggttacg
     6421 gattgatccg tcatcctgaa atgcagaaat acttagagga agaaatttcg acttctcttc
     6481 ttcaacattc aaatgcacag ttttctattt catggatgaa tcagcaatcg atcattgaac
     6541 aaagacagtt gcttgctgaa aaagaactgg ttaacttaga tcagcagatg aaagaagatg
     6601 aaactttatt agcagattcg ttacaaaaac gtctggcata tgaatatcct tatcaagctt
     6661 cttcacaaac cacaagttat caatctgtat ctgaaatcaa acgattattc gaagatccag
     6721 atgatacaca agaatcacgt ttgactctgg aaagcagtca gaacaaagca gcatcccgtc
     6781 aatttcgtta tacgcaagaa caactagcag aaccaaaatt tttgcaaaaa gatcggcaag
     6841 tgtcagcagc tgctgttgga actgctacgc atgctttgtt acaattactg ccattagaga
     6901 tgccaactac agagagtatc catcaaaaat tacaggaatt ggtaaggaaa cggttagtag
     6961 acgaaaaagt cgcgaaaaaa gtagatgttt cttctattat atggttcttt caaacagaac
     7021 ttggtcaaca gctgattgcc aacaaagaaa acgtaaaacg agaacaacct ttttccatgc
     7081 tgcttcctgc tgacgaagta tttcaagact atccaaatca agaagatgaa ctattaatcc
     7141 acggaatcgt cgatggatac ctagaagaaa aagatcatct caatatctat gattttaaaa
     7201 cagattttat tttacatccg gatgatccag cagaaataga tgcaatcgtc caaaaatatc
     7261 aaggacagct aagactttac caacaagcaa tgtcagaagc tttgaataag ccagtagaaa
     7321 atgttttcct aattttgctt cgagtgaaac aaattataaa cattaacaaa taattataat
     7381 tgagcaaact tgacttatgt tttgtaagga ttatgctata ctctgggaag aggtgagtat
     7441 gatggagcta acacagacag aattcgtttt atgccctaaa tttgaaaaat cattctctat
     7501 tttaggaaaa aaatggaacg gattgattat cgatgtacta ctcgaaaacg gtccgcaacg
     7561 ctttgttgag cttgcggcaa aaatcccgat ggtcagtgat cgagtattag tcgaacgctt
     7621 gaaggaatta gaaaaagaag gaatagtcac tcgaaacttt gcctgtagcg aaaagagccg
     7681 ttcagaatat ctcttgactg aaaaaggagc agacttgcaa aaagcgatgc gtcaaataca
     7741 agtttggagc gaaaaatgga tcacagagga agaatgcggt tgattttgta aaaaaaatct
     7801 tgtaaactat agtccatacg aataagtaaa gaacgatgac gaaaaagagt agtttggcta
     7861 aaccagttca gggagatctg tcgcagactg aaagcagatc ctgtgtttga aaaatgaagt
     7921 tcactttccg agttcgtctg ataaaatcag accggcaatt gtcgttaacg aagtaagagt
     7981 gcggtgtaag tcatttatcc gcaaattagg atggtaacgc gaagacctcg ttccttaaca
     8041 ggaatgaggt ctttttgttt tgtatttgga atttaaagga ggaacaagca catgtctcta
     8101 caagcacaat tagagagctt gaaagaagca acgctcgtca aaatcacagc ggcacaagat
     8161 ttaaatgaat taaatcaaat acgtgttgaa acgttaggaa aaaaaggacc gatcacagaa
     8221 gtattacgtg ggatgaaaga tctaagtcca gaagagcgac caaaagtcgg aagtttcgca
     8281 aatgagatcc gagatctttt gacagaagag atcgagcgaa aaaaacaagt attagaagaa
     8341 gaagcgttaa atgcagcttt ggcaaaagaa acaatagacg tgacactacc tggtagaaaa
     8401 gtaaaacatg gtacacgtca tatcgtgaca caaatcatgg aagaaattga agatattttt
     8461 gtgggtatgg gctatcagat cgtagaagga tatgaagtag aatctgatca ttacaatttc
     8521 gaacggatga atctgccaaa agatcatcca gcaagggaca tgcaagatac tttctatatt
     8581 tcagacgaga tattgattcg gacacatact tcaccagtcc aagcacggac aatggaaaaa
     8641 catgatttct ctaagggtgc tctacgaatg atctcgccag ggaaagtctt ccgcagagat
     8701 acagatgatg cgacccacag tcatcagttc catcaaattg aagggctagt tgttgataaa
     8761 aacatcacaa tgggcgacct taaaggaaca ttagaagtcg taatgaaaaa aatgtttggg
     8821 gaagatcgtg aaattcgttt gcgtccaagt tatttcccat ttacggaacc atcagtagaa
     8881 gtagatgtca gctgtttcaa atgtggtggt gccggttgta acgtatgtaa atacactgga
     8941 tggatcgaaa ttttaggagc tggcatggta cacccgaatg tgttgaagat gtcaggaatc
     9001 gatccagaag aatattcagg ctttgctttc ggccttggac cagaccgcgt agctatgttg
     9061 cggtatggag tgaatgatat ccgtaatttc tatcaaaatg acttacgttt cttaagtcag
     9121 ttcaaggggg agtaagaaaa tgttagtttc atataaatgg ctcaatcgtt atgtagattt
     9181 atcgaatgta acaccaaaag aattagcgga taagatgtct gtgacaggaa tcgaagtaga
     9241 gggagtaacg gttccagaag aaggcttgaa aaaaatcgtt gtcggtgaag tcaaggaatg
     9301 cgtaccacat ccagattctg atcacctttc tatttgtcaa gtcgatattg gcgaagacga
     9361 actgtctcaa atcgtttgtg gagcgcctaa tgtgaaggtt ggaatcaaag tgattgttgc
     9421 acttcctaac tcacgtatcg ctggtaatgt aaaaatcaaa aaaggaaaaa tgcgtggcca
     9481 agtatcaaat ggcatgattt gctcattaca agaaattggc tattcagata gtgttatacc
     9541 gaaagaatac gctgaaggta tctattatat gccacaagaa gctgtaaatg gcgatccagt
     9601 ttttccttat ttggatatgg atgattcgat tattgaatta tctatcacac cgaatcgtgc
     9661 ggatgcattg tcaatgcgtg gcgtagctta tgaagttggg gcaatttatc gtcagactcc
     9721 tacattcgat gacgaaaagc tggtagaatc ctcacgtcct gctagcgata aaattcaagt
     9781 ggaagttgaa gataaagaag cagttcctgc ttatcaaatc agaatcattg aaggagtaag
     9841 aatccagcca agtcctcaat ggctgcaaaa tcttttgatg aacgaaggca ttcgtccaat
     9901 caacaatgta gtagatgtga cgaactatat tttgctttta ttcggacaac cactacatgc
     9961 atttgactac gacaaattga aatcaaaaga gatctttgtc cgccgtgcaa aagaaaatga
    10021 aacattagta acactagatg gagaatctcg ggaattgaca actgacaatc tcgtcattac
    10081 taacggcaaa gaaccagttg ctttagctgg tgtcatggga gggttagact cagagatcac
    10141 gaatgaaaca acaacagttg cactagaatc tgctttattt gatccaattt cgattcgtcg
    10201 tacagcaaaa caatttaatt tgcgtagtga atcctctgca cgttttgaaa aaggaatcaa
    10261 ccatgcgact gttggagaag ccagtgaggt tgctgcagca atgatcgttt ctcttgcggg
    10321 tggggtagtt ctacaaggcg cggtcaaagg ctcagagatc aaagcagaag acgtatcagt
    10381 gaagatttca cttgaacgca tcaatcaata tttaggaaca tctcttgtcg ttaaagaagt
    10441 aaatgagatt tttgaagcac ttggatttag ctatgaagaa aaggagtatg tttattccgt
    10501 agtagtacca ccaagacgct gggatatcca aatcgaagca gatattatcg aagaagttgc
    10561 tcgtatttat ggatacgacc agttgccatc tacacttcca agtggagaaa cggttgctgg
    10621 aagcttgtca aaagaacaag aaactactcg taaaattcgt acaatctttg aaggaagcgg
    10681 attgagcgaa gcaatcagtt atgcattgac aacagaagaa aaatcaagac agtttgttat
    10741 aaatgaaagt aatattacac gtttggactg gccaatgagc gaagaacgtt ctgtattacg
    10801 aatgaatttg atcagcggac tattagatga tatcagttat aacactgccc gaaaaaatac
    10861 agagattgct ttatatgaaa ttggtcgggt gttcttccaa gaaaatgatc cacgtacaca
    10921 tctgccgcaa gaagtaaaac atgcagcaat cgctatttct ggtatttggg aagaaaaaga
    10981 ttggcagacg aaagctcaaa atgtagactt tttcaccatc aagggtcttt tagaaaactt
    11041 atttgaacaa ctaggcatca ctgaagatgt ccattatcaa acagtgacag aaatgaagga
    11101 aatgcatcct ggaagaactg ctgcgattta ccttggcgaa aaatttattg gttttgtcgg
    11161 tcaagtgcat ccaacgatta caaaaagtta tgatattcca gaaacatatg ttgctgagtt
    11221 tgatttatct gctatagtgg aagctgctca aaaagggatc gttttcgaag cagtgacaaa
    11281 attcccagca gtcagccggg acatcgcttt gcttgtaaaa gaaactgtga caaatcagga
    11341 attaacagaa gttatccgtt ctgctgccgg aagattttta acagatatcc aattatttga
    11401 tgtctatcaa ggagaaaaca ttgaaaaagg acataaatcc atggcgtata gcctgacatt
    11461 cgtcaaccca gaagcaacat tgacagatga agaaatcaat aaagcaatgg aaaaagtcga
    11521 aaaagcgttg gtagaaaacc tagaggcaag tattcgctaa gaaggaaaat atagtaagta
    11581 acgatcaagt agcttttgaa gaccatacat ttgaaaaaaa gatgtgacac aacttcgtca
    11641 catctctttt tttgatttta aaaaaggaat agcacagaga cgagataaaa aaacaggcct
    11701 ttacagcctg ctttttta
//
LOCUS       DAXQKX010000074        10662 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.076, whole genome shotgun sequence.
ACCESSION   DAXQKX010000074 DAXQKX010000000
VERSION     DAXQKX010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10662
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.076"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            333..2279
                     /locus_tag="ACF3MF_002351"
     CDS             333..2279
                     /locus_tag="ACF3MF_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFE3928288.1"
                     /translation="MIERHVNLLKLLSRQEDFKPASFFSDKLAVSTKTIYQDIELLED
                     YVVNYQVTIERLPSLGIKLIGDRKNVEHLISSVENYLEKDIYSPEKRRVEIIKEVLFG
                     DKPVSLTHLSQSFMVSKTSLYNDLRIINKIIGSGEVKLQSSAEGISFTGNEQAIQRAI
                     KQLVFYYANDMESKTFFQVLNMLFDSKVISVIHDLLFNDYSELTEKVSDYYVRSLIST
                     LVIQCNRLLKGHHLTVEEEFLFNSIRYMETYIVANGLIEELKAKLNLPFYDADKEYLC
                     RQLFAHRVTNNLKTSNEEYAMSVHKLIERMSEIEKIDLTQNDRLYQSLLYHVPAMVLR
                     LKKGIKIQNPLLENIKSQYSELFSIVWYAMSILEEEFDVTLTDDEVSLILIHFQIAIE
                     DQSKANNIIIICQYGISSAQLIYNKVRRFLPAKDNVEISTLDKFHLAEIGEVDLIISS
                     LSFDAGGIPLVRVSPLVSKTDYMNIMEAYTKYLIEEPSRFIQNELIPKAVKVPTISKF
                     VQSSLVKTGVQVESKEECLDLMISELEANSLVTEEFRASIFSREKMGNTNLESGVALP
                     HANPSMVIESNIFIVALKNAINWGDRKVKLVIMVSLAEEDVSEIRGVYEELYQFIGQK
                     EMVDRLLQVHDSEKLLRIFQQKGE"
     gene            2282..2737
                     /locus_tag="ACF3MF_002352"
     CDS             2282..2737
                     /locus_tag="ACF3MF_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFE3928289.1"
                     /translation="MYLDKELCLFQLEVKDQKELFQVMSEQLKNAGCVKDSFLEGITN
                     REQEFPTGLEVNQIGFAIPHTDSAHVNSSQICFASLKEPLVFSDMTDKSHEIPVRLVF
                     MLAMSQPHEQIDTLQNLVSLFQNEEKVNELLACTTKEAFIELVHSAGVY"
     gene            2751..4079
                     /locus_tag="ACF3MF_002353"
     CDS             2751..4079
                     /locus_tag="ACF3MF_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HFE3928290.1"
                     /translation="MDIVLNAFEWFIGLGSNVFLPLIIFVIGILFGLKPGKAFVSGVT
                     VGIGSIGLGLVLSLLSDGLGTAIQQMGEQYGGGLNILDIGVGVGGPLAYSTSLGILMI
                     PISLILNFIFVVLGWTKTLNVDIWNFWFAIFLGMITQSVTGNFWFGLIGAIVAVILQW
                     FLADRTQKTVSEFFGYPGISITHMMGLSGVLFAKPVNWVFDRIPGFNKIDADAETLTK
                     RFGVLGDTVVIGLIIGIVVGIMAGYDVAGIGNLGIMTAAVMKIMPKMVAMFMEGLMPI
                     AEAAKEFTNKKLNGRQVNIGMDAALTVGHPTIMSTSLLLVPISLLLALILPGNKVLPF
                     GDLAFFAFAICLMIPYFKGNIVRSLVGCSLYVVTTLYMATWLAPIITDVFTLASFDVG
                     TAGLVTMLLCGLWPVGLFVLLASYFGVIGIGGLGVVLVGASIYMNKVKKA"
     gene            4113..4397
                     /locus_tag="ACF3MF_002354"
     CDS             4113..4397
                     /locus_tag="ACF3MF_002354"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFE3928291.1"
                     /translation="MKKLLVICGAGHATSTIAVAKLSKWLEEEGLTDQVKIYQSKIAD
                     ELNKIDEYDAVVSTTIVPDVIKAKVTNGLGLLTGIGTDAIYADVKERLGV"
     gene            4399..4914
                     /locus_tag="ACF3MF_002355"
     CDS             4399..4914
                     /locus_tag="ACF3MF_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HFE3928292.1"
                     /translation="MRFHHDTLTIETVSGRPSYHDIRKELLDTVDTAGIENGMLVISS
                     PHTTCSLFFEETMHDTNFFGDDYLHVDINNVMETIIPKMTSENQYNSPGPKHIDFGTR
                     LSDPNYPAEKWVMLNTDAHLRSSIYGTNSMTLIVQEGKLLLGEMGRVYFVDWDQLRER
                     TRTINLMIMGE"
     gene            4930..5592
                     /gene="rpe"
                     /locus_tag="ACF3MF_002356"
     CDS             4930..5592
                     /gene="rpe"
                     /locus_tag="ACF3MF_002356"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFE3928293.1"
                     /translation="MTIAPSLLNAPIAEVKELFEILKEKNVDYLHIDVMDGCFVPDMA
                     FGPSVIKDIRPLTDVVFDVHLMIDTPEKIVTRFVEAGADIVTFHIEATKHAMKVIQLV
                     KEAGAKVGITFNPATPVSFIEPVLSLVDQVLVMTINPGTENKHFIQETVVKIEQLDVI
                     RKQNDYTYDIEVDGKIDNQTIKVCSKAGADIFVSGGFIFNGKNTPQEQIDKLNQSLEE
                     VK"
     gene            5599..6171
                     /gene="hxlB"
                     /locus_tag="ACF3MF_002357"
     CDS             5599..6171
                     /gene="hxlB"
                     /locus_tag="ACF3MF_002357"
                     /EC_number="5.3.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_function: GO:0043800 - hexulose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-3-hexuloisomerase"
                     /protein_id="HFE3928294.1"
                     /translation="MTNKDQNKNYLEAIILELQNNSKRINSVELEQFSEKIVQAKHIF
                     LAGAGRSGIAMQAFTNRLMHLGFSVSLVGEISSPHSQPGDLLIICSGSGETGSLKNLA
                     AKANQSGVSIALVTMKKDSSIGQLADSVLVLPGITKDENQREEDTFSQPMGSSFEQLA
                     FLTFDSLVLSLMDKTGESSETMFARHADFE"
     gene            complement(6358..7878)
                     /locus_tag="ACF3MF_002358"
     CDS             complement(6358..7878)
                     /locus_tag="ACF3MF_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HFE3928295.1"
                     /translation="MTKMESELLVQIKQLTQLLEIQQQENTLLREQIAEMNRRLFGRK
                     KETPPVDGQIDLLDDSTFNEPEHTGQESQEPITVSSFKRRKRKGLKALSLEGLPEVPI
                     HYELKGADCLCEDCGHTLHDIGATRLREEPLYVPAHIEKQVIYQHAYHCRECEALGET
                     KIKKAPVPKPLINNSLGSSSIVTQSIWEKFVKKVPAYRQEKEWHALGFPLDRKKITNW
                     HIKVSEMVLEPIYNCLHQELSNQEVLHADETSYRVLNTHKEKTFYWLYASGKSEEKQV
                     VLYEHANSRSVDEPKSFLESFSGFLHTDGYAAYGKLPVNNVYCWAHVRRKFFEALGKQ
                     PSPKSHAKIGLDFCDKMFRIERTFNKLSAEERFVARKETLQPVMTEFFHWCESFAYLP
                     KSQLGKAVQYAVNHKDGLQIVLLDGRLELSNNRAERAIKELVIGRKNWLFSKSLKGAR
                     SNGIILSIIQTAVANGLNIRKYLNHLFTEIPNLSSMTPEALRAYLPWNQQIQEICK"
     gene            complement(8121..8306)
                     /gene="tnpB"
                     /locus_tag="ACF3MF_002359"
     CDS             complement(8121..8306)
                     /gene="tnpB"
                     /locus_tag="ACF3MF_002359"
                     /inference="COORDINATES: protein motif:HMM:NF017528.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HFE3928296.1"
                     /translation="MPMLIDATALKHIFIVCGKTDLRKGIDGLAAFVIEEYDLDVYDQ
                     ALFLFCGTKKDRFKALY"
     gene            complement(8290..8472)
                     /locus_tag="ACF3MF_002360"
     CDS             complement(8290..8472)
                     /locus_tag="ACF3MF_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928297.1"
                     /translation="MNKKDIVPVQFSSAAQKSQIDTKPKLACRIKSEDKEIFIYNGMD
                     KYLLYTLLKELNANAH"
     gene            8713..8931
                     /locus_tag="ACF3MF_002361"
                     /pseudo
     CDS             8713..8931
                     /locus_tag="ACF3MF_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            9426..10025
                     /locus_tag="ACF3MF_002362"
     CDS             9426..10025
                     /locus_tag="ACF3MF_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFE3928298.1"
                     /translation="MKTVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLADVLEISRGRVVVKDRLAMKEQKTAKHNSVYISNKLRKTILEYVQQEFPDQ
                     LLQQDFDGYLFPSRKGTNEPLNRQSLWRIIHDAGTAIGLKDIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            10089..>10662
                     /locus_tag="ACF3MF_002363"
     CDS             10089..>10662
                     /locus_tag="ACF3MF_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbiH family protein"
                     /protein_id="HFE3928299.1"
                     /translation="MSTLYIIGNGFDLSHGLKTRYTDFSKWVEKSHSEIFDKIDTMIN
                     ENNEVRSTADDKIGWFNFESSLHELIQSPVFEDYVEESKDYLIGYGHEDWSDSAHHDF
                     QNMVYDYVVSLEELQQLFKEWIRKEIQPTIEHKIPKYQFSSDVLFFTFNYTDVLEILY
                     KQPKENIYHIHGSYDDIIIGHSENFDNFIGD"
BASE COUNT         3525 a         1675 c         1990 g         3472 t
ORIGIN      
        1 taggactcaa ttgttcatag atgagcattt gtaattaagt tatattataa taaaaaaata
       61 cgaattttag tgacgccatt atattgtttt tatttttcaa ttgtaatatt tcatattact
      121 tccataataa ggagtatttt ctattggaat atcttagctc ttttaaggat ttctcctttt
      181 ttgtttctca ttttttaaga ttatttggat ttcctttaca acaaacttcc acaagtatta
      241 ttgacataga tgtaattgag ggaagggggt tccagtgcta gaataaataa tgaaaagagg
      301 taacaaatgc tagcgttaag aggtgaacaa gtttgattga aagacatgta aatttattaa
      361 aattattaag tcgacaagaa gactttaaac ccgcttcttt ttttagtgat aaattggcag
      421 tgtcgaccaa gaccatttat caagatattg aattgttgga agattatgta gttaattacc
      481 aagtaacaat tgagcgatta ccttctttgg gtatcaaact cataggtgat aggaaaaacg
      541 ttgaacattt gatttcatcg gtagaaaatt atcttgaaaa agatatttat tctccagaaa
      601 aaagacgtgt cgagatcatt aaagaagttt tgtttggtga taagcctgtt tctttaactc
      661 atttgtctca aagttttatg gttagtaaaa catcgttata caatgacctg agaattatca
      721 ataaaattat tggcagtgga gaagttaagt tgcagtcatc tgcagaagga attagtttta
      781 ctggtaatga acaagcaatt caacgagcaa tcaagcaact tgtattctat tatgcgaatg
      841 acatggaatc aaaaacattt tttcaagttt taaatatgtt gtttgattca aaagttatta
      901 gtgtcattca tgatttgcta ttcaatgatt acagtgaact gactgaaaag gtttctgatt
      961 actatgttcg gtcattgatt tctactttag ttatccaatg taaccgttta ctgaaaggtc
     1021 atcatttaac tgttgaagaa gaattcctct tcaatagcat tcgctatatg gaaacgtaca
     1081 ttgtggcaaa tggtttaatt gaagaattga aggcaaaatt gaatcttcca ttttatgacg
     1141 cagataaaga atatctatgt cgtcaactat ttgcacatcg tgtgacaaat aatttaaaaa
     1201 ccagcaatga agagtacgct atgagcgttc ataaattgat tgaaagaatg agtgagattg
     1261 aaaaaattga tttgactcaa aatgatcgat tatatcaatc cttattgtat catgtgccag
     1321 caatggtcct tcgtttaaaa aaaggtatta aaattcaaaa tccgttatta gaaaatatca
     1381 aatctcaata ttcagaactc tttagcatag tatggtacgc catgtccatc cttgaagaag
     1441 aatttgatgt gactttaacg gacgatgaag tttccttaat tttgattcat tttcagattg
     1501 ctattgaaga tcagtccaaa gcaaataata tcatcattat ttgccaatac ggtatttctt
     1561 ctgcgcaatt aatttacaat aaagttcgac ggtttttacc agcaaaagat aatgtagaaa
     1621 tatcaacttt agataagttt catttagctg aaattgggga agttgatttg attatttcct
     1681 ctctttcctt tgatgcaggt ggtataccct tagtaagggt atctccattg gtaagtaaaa
     1741 cagattatat gaatattatg gaagcttata ctaaatattt aatagaagaa ccttcgcgat
     1801 ttattcaaaa tgaactgatt cctaaagcgg ttaaagttcc caccatatct aaatttgttc
     1861 aatcatcttt agtaaaaaca ggagtacagg tggaaagcaa agaagaatgt ttggatttga
     1921 tgatttccga actagaagcc aattcattag ttactgaaga gtttcgtgct tctatcttct
     1981 ctagagagaa aatggggaat actaatttag aaagtggtgt tgctttaccg catgcgaatc
     2041 catcaatggt cattgaatcc aacattttta ttgtagcatt aaaaaatgcg attaattggg
     2101 gcgatcgaaa agtcaaatta gtcattatgg ttagtttagc tgaagaagat gtatctgaga
     2161 ttagaggagt atatgaagaa ctttaccaat ttattgggca aaaagaaatg gtcgatcgct
     2221 tgttacaagt tcatgatagc gaaaaattac taagaatttt tcaacaaaaa ggagaataaa
     2281 aatgtatcta gataaagaat tatgtttatt tcaattagaa gtgaaagatc aaaaagaatt
     2341 gtttcaagta atgtctgaac aattaaaaaa cgctggttgc gtgaaagata gtttcttaga
     2401 aggtatcacc aaccgtgaac aagaatttcc aactggatta gaagtaaatc aaattgggtt
     2461 tgctatccca catacagatt ccgcacatgt aaatagctct caaatctgtt ttgcctcatt
     2521 aaaggaacca ctggtatttt cagatatgac agataaatct catgaaatac ctgtacgttt
     2581 agtctttatg ttggcaatgt cacaacctca tgaacaaatt gatacactac aaaacttagt
     2641 tagcctattt caaaatgaag aaaaagtaaa tgaattactt gcatgtacca cgaaagaagc
     2701 atttattgag ttagtacatt ctgcaggagt ttattaggag gaatagagag atggatattg
     2761 tattaaatgc ctttgaatgg tttattggat tagggtcaaa cgtcttttta ccactgatta
     2821 tttttgtaat cgggatatta tttggattaa aacctggtaa agcatttgtt tccggcgtta
     2881 ctgttggtat cggttctatt ggtttaggat tagttttaag tttattatca gatggtttag
     2941 gaacagcaat tcaacaaatg ggggaacaat acggtggtgg cctgaatatc ctagatattg
     3001 gcgtaggtgt tggtggacct ttggcttact ctacatcatt gggaatttta atgattccaa
     3061 tttcattaat tcttaacttc atatttgtgg ttttgggttg gacaaaaaca ttgaatgttg
     3121 atatttggaa cttttggttc gcaattttcc taggtatgat tactcaatct gttacgggaa
     3181 acttttggtt tggcttaatt ggcgcgattg tcgcagtaat tttacaatgg ttcttagcag
     3241 atcgtacaca aaaaactgtt agcgaatttt tcggctatcc aggaatctct atcacacata
     3301 tgatgggatt atcaggagta ctatttgcca aaccagtaaa ttgggttttt gatcgtattc
     3361 ctggatttaa taaaatagat gcagatgcag aaacattaac aaaacgtttc ggtgttttag
     3421 gtgacacagt tgttattggc ctaattatcg gtattgtagt gggtattatg gcaggctatg
     3481 acgtagcagg aattggaaac ttaggaatta tgactgcggc agtgatgaag attatgccta
     3541 aaatggtagc aatgtttatg gaaggtttaa tgccaattgc agaagcggcg aaagaattta
     3601 cgaataaaaa gttaaatggt cgccaagtaa acattggaat ggatgcagcg ttaactgtgg
     3661 gtcatccaac tattatgtca acttctctat tgcttgtacc aatctcatta ttgctagcac
     3721 taattcttcc aggaaataaa gtattacctt ttggagattt agcattcttt gctttcgcca
     3781 tctgtttaat gattccttat tttaaaggaa atattgtgag atcattagta ggatgttcgt
     3841 tgtatgttgt tacaacatta tatatggcaa catggttggc accaattatc actgatgtgt
     3901 ttacattagc aagtttcgat gtggggacag caggattagt aactatgttg ttatgtggat
     3961 tatggccagt agggttgttt gttttattag catcttactt tggtgtaatt ggaataggtg
     4021 gattaggagt tgttttagta ggtgcttcta tctacatgaa caaagtgaag aaagcttaat
     4081 cataaaatta aaataagaaa gaagagatca atatgaaaaa attattagtt atttgtggag
     4141 caggtcatgc tacttctaca attgcagtag caaaattatc aaaatggttg gaagaagaag
     4201 gattaacaga tcaagtgaaa atttatcaat ctaaaattgc tgatgagcta aataaaattg
     4261 atgaatatga tgctgtagta agtacaacaa ttgtccctga tgtaattaaa gctaaagtaa
     4321 cgaatggctt gggcttatta acaggtattg gtacagatgc catttatgca gatgtaaaag
     4381 aaagattagg tgtttaatat gcgttttcat catgacactt tgactattga aacagtttca
     4441 gggcgtcctt cgtatcatga tattcgaaaa gaacttttag atacagttga tacagcaggt
     4501 attgagaatg gaatgttagt aatttcgagc ccgcatacaa cttgctcact cttttttgaa
     4561 gaaacgatgc atgacacaaa cttttttggt gatgattatt tacatgtaga catcaacaat
     4621 gtaatggaaa cgattattcc aaaaatgacg agtgaaaatc aatacaacag tccggggcca
     4681 aaacacattg attttggaac aagattatct gatcccaatt accctgcaga aaaatgggtc
     4741 atgctaaata ccgatgcaca tttacgttca tctatttatg gaaccaactc aatgacttta
     4801 attgttcaag aaggtaaact tttattagga gaaatgggcc gtgtctattt tgtcgattgg
     4861 gatcaactaa gagagcgaac tagaacaatc aatctcatga ttatgggaga ataaacgggg
     4921 gaatagagaa tgacaattgc tccatcattg ttaaatgcac ctatcgcaga agttaaagag
     4981 ttatttgaaa tcttaaaaga aaagaatgtt gattatttgc atattgatgt aatggatggc
     5041 tgttttgtac cagatatggc ttttggacca agtgttatta aagatattcg tccactaaca
     5101 gacgttgtgt ttgatgttca tttgatgatt gatacaccag aaaaaattgt cacaagattt
     5161 gtagaagcag gagcagatat tgttaccttc cacattgaag ctaccaaaca cgcaatgaag
     5221 gtcattcagt tagtcaagga agcaggagca aaagtaggga ttacttttaa tcctgcaaca
     5281 ccagtcagtt ttattgaacc agtattatct ttagtcgatc aagtattagt aatgacaatc
     5341 aatccaggaa cagagaataa gcattttatt caagagacag tagttaaaat cgaacagtta
     5401 gatgtaatac gcaaacaaaa tgattatacg tatgatattg aagtagatgg caagattgat
     5461 aatcaaacga ttaaagtttg ttctaaagca ggggcggata tttttgtatc aggcggtttc
     5521 atcttcaatg ggaaaaatac cccgcaagaa caaattgata aactaaatca atcattagag
     5581 gaagtgaagt aaaagatcat gaccaataaa gaccaaaata aaaactattt agaagcgatt
     5641 atcttagaat tacaaaataa ctcaaaacgt attaattctg tagagttaga acaatttagt
     5701 gagaaaattg ttcaagctaa acacatcttt ctagctggtg caggacgctc tggaattgcc
     5761 atgcaagcat ttacgaatcg cttaatgcat ttaggttttt cagtcagcct tgtcggtgaa
     5821 attagttcac cacattcgca acctggagat ttattaatta tctgttctgg ctcaggtgaa
     5881 acaggtagtt taaaaaattt agcggccaaa gcaaatcaaa gtggtgtaag cattgcttta
     5941 gttaccatga aaaaagactc gtcgattggt caattagcag attctgttct tgtattacca
     6001 ggtattacca aagatgaaaa tcaacgagaa gaagatactt tttcacaacc tatgggttca
     6061 agttttgaac aattagcatt tctcaccttt gatagtttag tgttatcttt aatggataaa
     6121 acaggtgaaa gctcagaaac gatgtttgct cgacatgcag attttgagta gtagatttta
     6181 aagataaaaa accattctct aaatgctaat tattcagcaa atatgagaat ggttttttta
     6241 tttgattaga cataacttaa taattcagta gttttgagcg taagcgtgtc atagaatggt
     6301 acctaaacac aaatagcccg atttgataca ctcaaatcag gttatttgtg gcttatatta
     6361 tttacagatt tcttgtatct gctgattcca tggcaaataa gcgcgtagcg cttcaggtgt
     6421 catcgaagac agattgggaa tctctgtaaa aagatgattt aaatatttgc ggatgtttaa
     6481 cccattcgca acagctgtct ggataatact caatataatt ccatttgatc tagcgccttt
     6541 taagctttta gaaaatagcc agttttttcg accgatcact aactctttga tggcacgctc
     6601 tgctcggtta tttgaaagtt ccaagcgtcc atcaagcaac acaatctgaa gtccgtcttt
     6661 atgattgact gcgtattgaa ccgcctttcc aagctgcgat tttggcaaat aagcaaaact
     6721 ctcacaccaa tgaaaaaatt cagtcatcac aggctgcaac gtttccttcc tcgctacaaa
     6781 cctttcttct gcgctaagct tattaaaggt ccgttcgatt cgaaacatct tgtcacagaa
     6841 gtctaatcct attttggcat gactttttgg ggacggttgt ttacccaatg cttcaaaaaa
     6901 ctttctgcga acatgcgccc aacaataaac attgtttacc ggcagctttc cataggccgc
     6961 gtaaccatca gtatgcaaga aaccgctaaa tgattctaaa aaactttttg gctcatcaac
     7021 ggaacgcgaa tttgcgtgct cgtagagcac aacttgtttt tcttcgcttt tacctgaagc
     7081 atataaccag taaaaggtct tttctttatg agtattcaat acccgatagc ttgtctcatc
     7141 cgcgtgtaag acctcctgat tgcttaattc ttgatgaagg caattgtaga ttggctctaa
     7201 aaccatttca cttaccttga tatgccaatt agtgattttt ttacgatcaa gagggaaacc
     7261 aagtgcatgc cattcttttt cttgtcgata tgccggcacc tttttaacaa atttttccca
     7321 aatactctgt gtcacaattg aagaggaacc tagactatta ttgatcaacg gtttaggaac
     7381 aggcgctttt ttgatttttg tttctcctaa tgcttcacat tctctgcaat gataggcatg
     7441 ttggtagatg acttgttttt ctatatgggc aggaacatac aatggctctt ctctaagcct
     7501 tgtcgcaccg atatcatgta aagtatgacc acagtcttca cacaaacaat cggcaccttt
     7561 taattcataa tgaataggaa cttcaggcag accttctaat gaaagtgctt tgagtccctt
     7621 gcgttttctg cgtttaaaag aagataccgt aatgggttcc tggctttctt gtccagtgtg
     7681 ctctggttca ttaaaagttg agtcgtctaa taaatcgatt tgcccatcta cgggtggtgt
     7741 ttcttttttt cgtccaaaca agcgtcgatt catttcagca atttgttctc taagaagagt
     7801 attttcctgt tgctggattt caagcaactg tgttaattgc ttgatttgta caagaagttc
     7861 agattccatt tttgtcattt ttacaccacc attctagcga ttttcttaca tctattatac
     7921 cattttatga caacgaaaaa cagacaaaat ccttgattta acaaggtttt cgtctaatat
     7981 atcgcacctt ttttcgtttc ttttagcgta catttttctt cgattgaaag gccagtcagt
     8041 aagacttctt ttctggaacg cggccattga aggtacccac tttcaaatct tttgtacatt
     8101 aatacaaatc cattttgatc ctagtaaaga gccttgaagc gatctttctt cgtaccgcaa
     8161 aataagaaaa gcgcttgatc gtaaacatca aggtcatatt cttctataac gaaagctgct
     8221 agtccatcaa ttccttttcg aagatctgtt tttccacaaa cgataaaaat atgtttcaat
     8281 gcagttgcat caatgagcat tggcattcaa ctcttttaac aaggtataca aaagatattt
     8341 atccattcca ttataaataa atatttcctt atcttccgat ttgattctgc aagctagttt
     8401 tggcttggtg tcaatttgcg atttttgagc cgcacttgaa aattgaactg gtacaatatc
     8461 ttttttattc attcgttttt ctccttctat atttgatagt ttaattatag aagaaagata
     8521 atcggcgtac gagatactat cctatgacac gcttacattt aatttaatat tttgcctcaa
     8581 attagccaca ctttttatag aactaagagg aaaaatgaag ttttcttcct attaatatag
     8641 ttgtttgaaa tcttaaatat agcgttttac gatgtaatgg gaagtatggt gaataaatca
     8701 actatgttcg tacgaagcat ttactcaact aatttaatcg aatctttcaa taaacaaatc
     8761 aagaaataca gccaccgcaa ggaacagttc caaaatgaag agtcgatgga acgtttctta
     8821 gtctcgtctt ttgatactta caaccaaaaa ttcctaggtc gcagtcataa aggtttccaa
     8881 caggccgaag gcgagctcga acaaatgctg agtcaaccga tggagaatta gaaacaatct
     8941 acagtaggga agaaccattg acacaaaatt attgacgctc ccaactaaaa gtgtcaaaat
     9001 aatgatgaaa tcatttagtt cttataaatt agaaaagaga aaataaatat tccatatcta
     9061 ctttattgga tccgtaacat gactaaattc tgaatacttt ttaaagctta tcatttggta
     9121 aaactgaata taagttaatt atatagactg aaaattttga attttcagaa tagaataact
     9181 taaaagtact gacaaaattt tttaaagggg caatattaat gttctgagat aatcaaatcc
     9241 taccgaaaat atcaaaaatc caatgtgaca caatcagatt gtgtctcatt cgagggaatc
     9301 acacaatccc acgtggctct aggcagaatt gaatttttgc ttggggcttt ttccttatat
     9361 tgattttgaa tgagacttat tatatgttat aatgcaatta agtatcattg gagagggcga
     9421 agaaaatgaa gacggtagaa cctattcgag acaaaaaaaa gatcgatgcg atgaaggcaa
     9481 tcttggcttc gggaaaatat ggccaacgaa atttggttct tttttcgatt gggatcaaca
     9541 ccgcctatcg catttctgat ttgcgtcaat tgaagctggc cgacgtgctg gaaatttcac
     9601 gcggtcgcgt ggtggtcaaa gatcgattag cgatgaagga acaaaaaaca gctaaacata
     9661 attcggtcta tatttccaac aaattgcgaa aaacgatttt ggagtacgtt caacaggaat
     9721 ttcctgatca actccttcag caagattttg acggttattt gttccctagt cgaaaaggga
     9781 cgaatgaacc gctcaaccgc caaagtctgt ggcgaatcat tcatgatgct ggcacggcaa
     9841 tcggattgaa agacattggc ccacattcca tgcgaaaaac gttcggttac tttctctata
     9901 aacaggggac caaaacagaa atcattcagt ccttgttgaa ccattcttct cagcgcgaaa
     9961 cattgcggta tattggtatt acacaagaag acaaagatac agctgtaaaa agcttagatt
    10021 tataatataa aagttaagtt taaacatgga tagttttaaa ttagtagatt gagtgttggg
    10081 aggaaagaat gagtacatta tatattatag gaaacggttt tgatttaagt catggtttaa
    10141 aaactagata cactgatttt tcaaaatggg ttgaaaaaag tcatagtgaa atattcgata
    10201 aaatagacac aatgataaat gaaaataatg aggtgagaag tacagctgat gataagatag
    10261 gttggtttaa ttttgaaagt agtttgcatg agttaattca aagtccagtc tttgaagatt
    10321 atgtagaaga gtctaaggat tatctcatag gttatggaca tgaagattgg tcagattctg
    10381 cccatcatga ttttcaaaat atggtttatg attatgttgt ttctctagaa gaattacaac
    10441 aacttttcaa ggaatggata cgcaaagaaa tacagccgac aatagaacat aaaattccaa
    10501 aataccaatt ttcgtccgat gtactattct ttacattcaa ttatacagat gttttggaaa
    10561 ttctatacaa gcaaccgaaa gaaaacatat atcatattca tggcagttat gacgatataa
    10621 taatcggcca ctccgagaat tttgacaact ttataggaga tc
//
LOCUS       DAXQKX010000075        10518 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.077, whole genome shotgun sequence.
ACCESSION   DAXQKX010000075 DAXQKX010000000
VERSION     DAXQKX010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10518
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.077"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            163..381
                     /locus_tag="ACF3MF_002364"
     CDS             163..381
                     /locus_tag="ACF3MF_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928300.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(670..1182)
                     /locus_tag="ACF3MF_002365"
     CDS             complement(670..1182)
                     /locus_tag="ACF3MF_002365"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HFE3928301.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(1196..3493)
                     /gene="recJ"
                     /locus_tag="ACF3MF_002366"
     CDS             complement(1196..3493)
                     /gene="recJ"
                     /locus_tag="ACF3MF_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HFE3928302.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(3635..4078)
                     /locus_tag="ACF3MF_002367"
     CDS             complement(3635..4078)
                     /locus_tag="ACF3MF_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapA
                     domain-containing protein"
                     /protein_id="HFE3928303.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(4079..4867)
                     /locus_tag="ACF3MF_002368"
     CDS             complement(4079..4867)
                     /locus_tag="ACF3MF_002368"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HFE3928304.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(4864..5805)
                     /gene="rnz"
                     /locus_tag="ACF3MF_002369"
     CDS             complement(4864..5805)
                     /gene="rnz"
                     /locus_tag="ACF3MF_002369"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HFE3928305.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(5982..6569)
                     /locus_tag="ACF3MF_002370"
     CDS             complement(5982..6569)
                     /locus_tag="ACF3MF_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HFE3928306.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(6790..8103)
                     /gene="obgE"
                     /locus_tag="ACF3MF_002371"
     CDS             complement(6790..8103)
                     /gene="obgE"
                     /locus_tag="ACF3MF_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HFE3928307.1"
                     /translation="MSMFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGG
                     DVILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAET
                     GALLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVL
                     ADVGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLE
                     RPQIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNAT
                     ADLLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTN
                     FDHDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            8400..9410
                     /gene="gap"
                     /locus_tag="ACF3MF_002372"
     CDS             8400..9410
                     /gene="gap"
                     /locus_tag="ACF3MF_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFE3928308.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(9495..10430)
                     /locus_tag="ACF3MF_002373"
     CDS             complement(9495..10430)
                     /locus_tag="ACF3MF_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFE3928309.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT         2908 a         2370 c         1821 g         3419 t
ORIGIN      
        1 aaaacttttt aaaaagagtt tgagacgttg gtctcaaact cttttttcgc ccgggttctt
       61 cttctttcaa atttttatca cttccctctt tacaaaccga acaaatattc gtatactaaa
      121 tatacgaaca attgttcgca taaattaaag aggtgagaat tcatgaaatc aatgagacgt
      181 cttggcttag tattaactgt tttgttttta ggtattatta ttggtaattt cggcatacgt
      241 ccagctttac ttgtgtttgt tccgttattt actttgtggt tcatgttgtg ggatgaaaag
      301 aagtaccgtc aatctgagcg gcgcagaatt catgaagatc atttctatca tgagccctac
      361 tacagatcca ggcaatcata ataaggattg actgctaatt attcaaaaga caagaagtta
      421 aacttttacg ggggtgtgac aaaaatcggt cacatccttt ttttcgaata aacggtgttc
      481 taaagccagt ttttcggtat taagtcaaat tgcggaaaaa gtgatttttt aaacttctac
      541 tggtctttgc ttgtttccat ttataaaaaa atagcgaccc tcaaaagtca gatagagaat
      601 ctgacttttg agggtcgctt taaaatcgct tctttaagaa taacatcaag aatagcttct
      661 tttttctgct taatattcca ttaatgtaat gatgtcatat cctttgattt tgtcgcgtcc
      721 atggagatcc atcaattcga tcaaaaatgc gcagcctacg actacaccgc ctaattgttc
      781 gatcagttcg atcgtcgctt tgattgttcc tccagtagct agcaaatcgt cacaaatcag
      841 cacacgttga cctggtttaa tggcatcctt atgcaatgtc aatgtatctg ttccatattc
      901 taatccataa gtcacttcga tggtttctcg aggtaacttc ccttttttgc ggactggggc
      961 aaaaccgact cctaactcat aagcaacagg acatcctacg atgaatccac gggcttctgg
     1021 cccaactacc atatcaattc gtttttcttt tgcataattt acgatttgtt tagtagcttc
     1081 ccgataagcg tcaccatctg ccatcagtgg ggaaatatct cgaaacacaa ttccttttga
     1141 cggatagtcg ggaatactgg caatataatc ttttaaatcc actctttgtt tcctcctagg
     1201 ttgttaacca tttctttatg gtaggaatat cgctcaaaag caaaaattcc tcaactttga
     1261 ttttattgag ccgtcgctgg tataatctgc tctcagtcaa aggatgactt tctgggctag
     1321 cgactttttg taaaacaccg ttctctattg taacaaattt caattcaaaa aacacctgta
     1381 tcataaaaat taataatttt tcagggatac gcaaatattg agctattgct tttattttat
     1441 gacgtatatc aattcgttct tgagaatgga tcaatttaaa caattttgcg tactgttctc
     1501 ttgtgcctac cccattcaaa taggcctcat caggtgaaat ccccatcaga taaacacgat
     1561 tgaatgaata agaccgaaaa acttctttca gatccgctaa atcatctgga caatccataa
     1621 caactagaga gtttggtttt cttttttcaa ttattgcctt tacagaatct agtccttcga
     1681 aaacaatcgc agcttcctgg ataatctcag gcacgaattt caacgtcgaa gaatcaaatg
     1741 ctaaataaag gctaccttcc gacgttcggc tctgttcacg gaaacgtttt gcccgccaat
     1801 caaatacttg cagaccaccc acagaaaaat cagataccat cagctgcggt ttcttacgcc
     1861 cgttccattc attgatcgaa agctttccta ccacatctac ctgattattc agcagttctt
     1921 cttcttgagt accaaaacca aaagcgaccg catcaagctg actcgatgca tcggaaagga
     1981 caaatttcag atgctgttgg tttgctccga ttcttttgat attttctgct tggacttgtc
     2041 gaaataaaaa ctgaggcaaa ggattatccg taccaaatgg cgccaatagt ttcagctcat
     2101 caattcgctc tactgttact tcatttggca gcaatacttc atcaattctc aactcaggcc
     2161 ctctcatcaa gtcaatttga tgatcgacta tatattggtt catcttctcc tgtagtatag
     2221 tgacattttc acttggcatc gttaaaccga ctgctgcatg atgtcctccg aagtaagtaa
     2281 ataaatctcg catctggtca agcatttcaa aaagattcaa ggcttcaata ctacgtccag
     2341 atcctttagc tgatccatct tcttttaaag taaggacaag cgttggttta cccgtttcat
     2401 tcattatttt cccagcaaca atgcccaaaa cgccttcatg ccatcctcgg tttaccaata
     2461 gatggatatg attctcctta ttgaccatcg ctaatgcttc ttgtgttatc tgctctacga
     2521 ttgcttttct ttcttcattg atctcattca atttttttgc ttgaacggat gcttcctctt
     2581 catcaaacgt cgcaagtaac gagacggcag gacgtggatc gcccatccga ccgattgcat
     2641 ttagtctggg agcaatcgaa aaaccgatcg ttgtttcgtc tgcgtccctc atttttacgc
     2701 cgctttcttc aaatagcgcc tgaagtccta tccgttctga atgatgaatg gcatcgattc
     2761 ctaatgaaac aaggattcga ttctcatcag tcaatgaaac taaatcggcg atcgttccta
     2821 tcgctactaa atccaaaaat tctgcaggcg gttcttccaa taatgcagaa gctactttga
     2881 atgctactcc gactcctgcc aaatctggaa atggatagtg ccccgctgga tgacgagggt
     2941 gaacaatcgc ataagcgtct ggtaaattct caggtagttc gtgatgatct gtaatgatca
     3001 cgtctacacc agcttgctga gcgtatgcta ccgcatcatt tcctgctacc ccgttatcaa
     3061 cagtgatgat caactggatt ccttcttcga tcttttcttg gtataccgat tggtttggtc
     3121 catacccatg ctcaaatcga tttggcagga atacttctac ttctgcacca agtaattcca
     3181 gtgtttcttt cattaccgtt gcactggtga tcccatctgc gtcataatca ccgtaaacga
     3241 ggattttttc tccactgatt acagcttctt ggattcggct gattgcttta tccatatcgt
     3301 gtatcagata cggatcatgt aattcttgtt cctttggatg taaaaatcgg ttgatatcct
     3361 tttcctcatg gtaacctctt tgccacagta acttaccgac aaatggagat aatttcagtt
     3421 cacggatcat ttggagaaag gattcagaag gctctgtctc gcttaacttc caatcaaaat
     3481 ttgcttgtct cactttctca ctcctaactt agttattata gcaaaggaaa tcagcaaaaa
     3541 aaagcagaaa gaaagaataa aaacagatca gatccgctag acagatgttc agcaggacct
     3601 gatcttttgt acgaccattt atgaaatatc cctattagtc aaaataattg aagctttgtt
     3661 tgggcgattg agttttttgt tcttccggcg ctttcaattg actgatttgt gcggttttcg
     3721 cttgtaactc cgcctgataa gcagcttcca actccgcacg ttcgtttcta aactcgcgtt
     3781 gctgttcttc ttttgcttct tcaattttct tttgaagttc tgtttgatat tctgacattt
     3841 cctgagtcag ctgtttgatt tgcttttttt gctgccatag tgttgccgaa gcagtcaaaa
     3901 atacaatcag tgcaccaatc agcgcagaac cgatgatcac taagatcaat ggcgcagaaa
     3961 aggaagtgaa gccaaaactt acaggaacat ttttattgtt caatacagca aaaagaacaa
     4021 taatcaaaac taaaacaaat ccaagaatca cattgctttg ctttttcaat tccttcacct
     4081 actttttgtt aaaaattccg ctggctaaat aatcaccaat cgttggaaac agcgtataaa
     4141 attttgatgc aacttctaaa ataaacggtt gattgatttc ccgttttgga tgtctcatat
     4201 tgcggacgat catttttgcc aacttggcag gttctaaaac gatttgtccg actttttcca
     4261 aatagcttcc gcttggatca gccttatcga agaaatttgt ctcgattgga cctggattca
     4321 ctgtcgtaac agctacgcca agtggtttca attctaatcg caaagcgttg gagaagccaa
     4381 ggactgcaaa tttcgtggca gaataaaccg ttgattttgc agttgccatt tttccagcca
     4441 tagaggcgat attaatgata tgaccttgtc ttctttctgc catatcgatc gcaaattttt
     4501 gtgtcaaaac catcattcct aagatgttga cttcaaacat atcgtatgct tttccaaggt
     4561 cgaatgtaag gaagtcttcg aaaatcccaa aacccgcatt gtttaccaga atatcgacgc
     4621 gcccgacttc ttccatcacc ttttcatata attcgtccac gctttcagga ttgctgacgt
     4681 ctaccttgaa agcataagcc tctttgccgc tcaagcgtct gcactcgtct ctgacacctt
     4741 ctacaaatgc cattcttcgt gcgcaactta taacgattgc tccttgcttt gctgcttcat
     4801 aacagatttg tgcgcccaga ccgcctgaac tacctgttac taaaacaact ttatcttcta
     4861 aattcatgcc tcttcctcct cgcgaaatgg aatctcaatg ctatcaaaat ctttcataat
     4921 cgtcgtgttt tcaaacactt cttgtgcttc tttttcaagc tctaaagctg cttttcctaa
     4981 atatctcgca ctgatatgag taagtagcag ccgttttgcc tgcgcttctt ttgcaacttc
     5041 agcagcttga tgagtcgtgg aatggaaata gttgtgcgcc attcttgctt catctttatt
     5101 aaatgtgctt tcatgtacca gaatatcgct attttccgca agcacaacgg aattatgtgt
     5161 ttttctcgta tcgcctaaaa tagtcacgat tcgtcctttt ttatctggac ctacgaaatc
     5221 ttttccattg atcgtccgcc catcttctag ttggatcgtt tcaccttgct tcagtttgcc
     5281 gtacagtggt ccagctggaa tacctaattc ttttagacga tccacctgca attctccttt
     5341 atgatcatgt tcaaccacac gataaccaaa actgtcgatc ccatgattta gtttttttgt
     5401 ataaacagaa aattgctgat cagtaaaaat cggggctgtt tcatttagct caatgaattt
     5461 cagcggataa cttaaacgcg tttgcgaaat acctaaagag acttttatgt attcctctat
     5521 cccttttggc ccgtaaatct ctaatggcgt atccccacct tgaaatgacc ggctgctgat
     5581 gagcccggga agtccaaaaa tatgatcgcc gtgtaaatgt gtaatgaaaa ttttaccgat
     5641 ttttctcgga cgaatagtcg ttcgcaaaat ctgcatttgc gtgccttcgc cacagtcgaa
     5701 caaccaaact tcattgcgct cgtctaaaag tttcaatgct atacttgtca catttctatg
     5761 ttttgcagga acacctgcac ctgttcctaa aaattgtaat tccataatct acctgacttt
     5821 ctttaagttc ctctttaatt ttagggtaaa aagaagggat aatcaaccgt aagtcgagaa
     5881 tgggttcaaa ttaaaaataa cgttctaaag cgatagcgtt ttctttgaaa attactataa
     5941 aaacagcagc gaacccgttt gagatcctct gctgtttttt attaatttga agatccagaa
     6001 ctttcattgt cgttggaagt ttgcggatgt ttgtccttcc aagtcttttg tgcagcttct
     6061 ttcgcatgat tttcagcttc tttcgcatca tgcacatctt tttcgacatc ttcataatcc
     6121 aagcgagtaa tttctccgcc taattccatc attaccaatt gattcagtgg gcgattgtcc
     6181 tcttcatcag caatcaagat cagtcctgta gctccttcac cgattttatt tcctacaaag
     6241 tcgaacacgg tctgggcatc ttttatttct ttggcatctt gtgtcgcacc gatcattcct
     6301 ccggcaaacc atcctaataa aatccctagc ggaccaccta atacaccaac caacattccg
     6361 attaatccac ccgtagaaga tttgttatta ccggtaaagt cgataaaatc ttctattttg
     6421 aattgatgtg tcccattagg atcatggctg acaactgcca tctgttctcc tttaatcgaa
     6481 cgaacagcat gtaacttttt gatttctgaa aatgcctgat atgcctggct ttctacttga
     6541 aaatttaaaa tgattactcg tttgctcatt aaaaacgccc ctttcatacc ttcttgttat
     6601 ttattttacc tttaattgta aaataagaaa agaaaagcac tctttttttc caataaaata
     6661 gggctgtgac aaaagtcgta tcacagctcc tttttccgaa taaacggcgt tcttgaagct
     6721 gatcacttct gtcacaacct cccttaaatc tgaatctata ttttttggta tttgttttta
     6781 tttgcttgcc tattcgacaa attcaaattc aaactcaccg atacgtacaa ggtcgccatc
     6841 tttcgcaccg cgtgcccgaa gagcttcatc cacacccata ccacgtaatt gacgagcaaa
     6901 acgcatcact gtttcatcat gatcgaaatt cgtcatttgg aataattttt cgatcttctc
     6961 accagataag atccacgttg catctgaatc acgatcgatt tggaactcag gaccttctgg
     7021 attgaatcca tagtgtacag tttcttcttc cagttcttct tcgtacaatg ggaattctgg
     7081 cgttacttct aacaaatctg ctgtagcatt caataacgcg tccaatcctt gtcgagtcac
     7141 tccagaaatt ggaaatactg ggatgtcatc agcaaattca tcttcttttt ccttgttcag
     7201 ctgttctttg aatttcacta gattttccgg tgcatccggc atatccattt tgtttgccac
     7261 gatgatttgc ggacgctcta gcaagcgtaa gttataagta gataattctt tgttgatggc
     7321 aagatagtct tcataaggat ctcgtccttc catcccactc atatcgatca catgtaaaat
     7381 tactcgtgtt ctttcgatat gacgaaggaa ttgtgtaccc agcccaacac cttgcgaagc
     7441 tccttcaatc aagcctggca agtctgctgc ggcaaaactt ctgccatcac ttgtagtaac
     7501 cattcctaga ttaggtacga gcgtcgtgaa atgataagcg ccgatttttg gacgagcaga
     7561 tgaaataacg gatagtaaag tcgatttccc gacagatgga aaacctacaa gtccaacgtc
     7621 tgccaatact ttcaattcta gttcgatttt tcgctcttgt cctggttcac cgttttcagc
     7681 aatttccggt gcaggattcc gaggagaggc aaaacggata ttccctcgtc caccgcgtcc
     7741 accttttgcc acaactagtg tttgaccatt ttcaattaaa tctcctaaaa gagcaccagt
     7801 ctccgcatct cggacagtgg ttccttgtgg tactttaaca taggtatctt ctgaaccacg
     7861 accgtgcatc cctttactca tcccattttc acctggctgc gctttgaaat ggcgattgaa
     7921 ccgaaaatcc atcaatgtac gtaacccttc atcgacgatc aagatgacat cgccgccacg
     7981 accaccgtct ccgccagccg gtccgccgtc aggaacgtat ttttcgcgac gaaatgcaac
     8041 cattccgtct ccgcccttgc cagctttcac atcgatcgtt acttgatcta aaaacatgga
     8101 cataattaag tcctcctatt attcatttat ttatttgact gcctgaattt ccacaataaa
     8161 caaaagtctt acttatttta tcggtgaaat ctgattttgt ctatcatttc agcaaaaaga
     8221 ttgtttacct tcttcttttt ttatcatttg gtaaggtttc caaccttttt tctgctacca
     8281 agtataattt tttgacaaaa tattctttgc gtagcagaat aacagtgtat taattgtatt
     8341 aattgtatta attgaggatg ccgtttcaca gcacccctaa taaaggagga acttttgata
     8401 tgacagtaaa agtaggtatt aacggatttg ggcgtattgg ccgtctggct ttccgccgca
     8461 tcaaagaagt ctcagatgat attgaagtag tagcaatcaa cgacttaaca agtccaacta
     8521 tgttagcaca attattgcaa tttgactcta ctcatggtac ttatcctggc acagttactg
     8581 caacagaaga ctcaatcgta gtggatggcg aagcaactcg tgtttatgca gaacccgacg
     8641 caagcaaaat cccttgggca aaagaaaacg gtgtagatat cgtactagaa tgtactggtt
     8701 tttatacatc tgaagaaaaa gcaaaagcgc atttagatgc tggtgtcaaa cgagtagtta
     8761 tttctgcccc agctggtgct atgaaaacca tcgtctataa cgtcaatgat gatacattag
     8821 atgaaaacga caaaatcatc tcagcaggtt catgtacaac aaactgttta gcacctatgg
     8881 cttatttctt aaataatgaa tttgggatcg aagttggtac aatgacaaca gttcatgcct
     8941 acacttccac acaaatgctc ttagatggac ctgtaaaagg cggtaatttg cgtgctgctc
     9001 gttcagctgc tgacaatact atcccacatt ctactggtgc tgcgaaagca atcggcttag
     9061 ttatccctga gctacaagga aaattacaag gacacgcaca acgtgttcca gtcgttgatg
     9121 gttcattaac tgaattggtt tcagtattga aaacaaaagt aactgctgat caagtaaacg
     9181 aagcaatcaa aaaacacaca gttgacaatc cttcattcgg gtatgatgac cgtcaaatcg
     9241 tttctagcga tgtcattgga acaactcaag gttcgatctt tgacccaacg caaacagaag
     9301 taacaactgc tggtgatttc caacttgtta aaactgttgc atggtatgac aatgagtatg
     9361 gatttacttg ccaaatgatt cgcttactag aaaaattcgc taacttgtaa tttgatagat
     9421 caatcgataa aagaagcctt tgactggatc cagtcaaagg cttctttctt ttcatcccct
     9481 acttttaaac tcgttcaatg aacatattgg cttaaaaatt gttggactac ttgctgatat
     9541 ttttcaggat ctgtcttgta tgcttccgca tgctcggctc cttttacaac atacttttct
     9601 tttggtccct tcgttgcacg atagacctta tctaacattt caaatggtac aaatgtatct
     9661 tcgtctccat gtataaagag cattgggcgc tggtttttct tcaattgttc cactgcattt
     9721 gcttcaccga aaaagtagcc agcacggact tttgtcacta gactcgttac ttgcataagc
     9781 ggaaatgctg gaagactaaa catatcgtct agctgataag caagctcatc atgaacggaa
     9841 gaataaccgc aatcttcaat gattgctttc acattatctg gtagtttttc tccgctagtc
     9901 atcataactg ttgctgctcc catgctgaca ccgtatagaa cgatttcttg cgattttcca
     9961 ttgttttcta gcactttgtt tatccactgt acatagtctt tacgctctgg ccatccaaat
    10021 ccaatgtaat ccccttcgct ttttccatgt cctcttgcat caggaacaag gacattgtaa
    10081 cccatatcat gaaacatctt tgcgtaattg gtcatcgttt cagcgtttcc catatagcca
    10141 tgagccacaa gagctgtttt ttcacttttc gtttcagcag gaagataaat cgctgataat
    10201 ttcagaccgt cttttgaagt gatggtccaa tcgcttcggt tttcttttga actaaaccat
    10261 ttatgtgcat ccgtttcttt ggatgtctgt gttgtaccag gtgtatcttc gtctaaaaag
    10321 tctttctcag aaggcacaac agcataatta taaaaataat tccctgcaaa cactaacgca
    10381 acaatcagag ctaaagcgac gcctaaaagg attttcatcc aaagtttcat aaatcatcca
    10441 tctcatttct cttttttcat ataaccttga attagtataa tcaaagaatc tctactatgc
    10501 aatgttcatt tttataac
//
LOCUS       DAXQKX010000076        10496 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.078, whole genome shotgun sequence.
ACCESSION   DAXQKX010000076 DAXQKX010000000
VERSION     DAXQKX010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10496
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.078"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(1..460)
                     /locus_tag="ACF3MF_002374"
                     /pseudo
     CDS             complement(1..460)
                     /locus_tag="ACF3MF_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
     gene            complement(712..1071)
                     /gene="rplT"
                     /locus_tag="ACF3MF_002375"
     CDS             complement(712..1071)
                     /gene="rplT"
                     /locus_tag="ACF3MF_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HFE3928310.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            complement(1124..1324)
                     /gene="rpmI"
                     /locus_tag="ACF3MF_002376"
     CDS             complement(1124..1324)
                     /gene="rpmI"
                     /locus_tag="ACF3MF_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HFE3928311.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            complement(1396..1920)
                     /gene="infC"
                     /locus_tag="ACF3MF_002377"
     CDS             complement(1396..1920)
                     /gene="infC"
                     /locus_tag="ACF3MF_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HFE3928312.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     misc_feature    complement(1964..2089)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            2240..2872
                     /locus_tag="ACF3MF_002378"
     CDS             2240..2872
                     /locus_tag="ACF3MF_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFE3928313.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGNQSYLDAKN
                     MVLRESHIQKLTMQKTGLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTTIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(2874..3779)
                     /locus_tag="ACF3MF_002379"
     CDS             complement(2874..3779)
                     /locus_tag="ACF3MF_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFE3928314.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWEIALIISLVLSIWMLIALWRRIR"
     gene            complement(3864..4523)
                     /locus_tag="ACF3MF_002380"
     CDS             complement(3864..4523)
                     /locus_tag="ACF3MF_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFE3928315.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     CVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVS
                     I"
     gene            4839..5783
                     /gene="mvk"
                     /locus_tag="ACF3MF_002381"
     CDS             4839..5783
                     /gene="mvk"
                     /locus_tag="ACF3MF_002381"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HFE3928316.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            5776..6753
                     /gene="mvaD"
                     /locus_tag="ACF3MF_002382"
     CDS             5776..6753
                     /gene="mvaD"
                     /locus_tag="ACF3MF_002382"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HFE3928317.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKKGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            6766..7851
                     /locus_tag="ACF3MF_002383"
     CDS             6766..7851
                     /locus_tag="ACF3MF_002383"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HFE3928318.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            7848..8912
                     /gene="fni"
                     /locus_tag="ACF3MF_002384"
     CDS             7848..8912
                     /gene="fni"
                     /locus_tag="ACF3MF_002384"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HFE3928319.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKDPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAQEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(9161..9964)
                     /locus_tag="ACF3MF_002385"
     CDS             complement(9161..9964)
                     /locus_tag="ACF3MF_002385"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HFE3928320.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIRDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(9984..10307)
                     /locus_tag="ACF3MF_002386"
                     /pseudo
     CDS             complement(9984..10307)
                     /locus_tag="ACF3MF_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="5-deoxy-glucuronate isomerase"
     gene            complement(10340..10477)
                     /locus_tag="ACF3MF_002387"
                     /pseudo
     CDS             complement(10340..10477)
                     /locus_tag="ACF3MF_002387"
                     /inference="COORDINATES: protein motif:HMM:NF018513.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
BASE COUNT         3106 a         2220 c         2008 g         3162 t
ORIGIN      
        1 aatacctaat gacatcaaga tcggcaacac aataactgca atagaaatca ctggtccgat
       61 tcctgtcatc gacatgaata taacagcggt tacaatacat agtaagctca tcgtgattct
      121 tggcttgtcc cctccaagtt caactacctt tcgaatcagg gtagctgcga ttccgctatc
      181 tactagaaca cgcccgaaaa aggcaccaaa gaagacattt accaagatcg atttggcgta
      241 ctcagctggc cccgtcgtat agatatgcgt caacacatca attactcctt gcccttccat
      301 cgccgagttt ggtgaaaacg tgtttccgac tagcgctaat cccatccata cagtagccat
      361 gatgacaaaa gccgaccatc aagttgtagc cttttacaca gtaccagacc atgaaaaaga
      421 atgagataac taacaaaata ccaataataa tatcactcat gttattcctc cgtccatttt
      481 gtttttctga taagcaaact aatatatcag tcaaactcat tctaacttat gtagttagcg
      541 ctttcattaa aggatgacca taaatgttca gttttcaatt aaaaaacctt aattatgtta
      601 ttttagactt atacgttatt gtcctgtttc atttgatgga ggattgtaaa taaaaaaaga
      661 ggaaagaaca taacttttcg ttatcttctt tcctctttat aattgtttag cttatttagc
      721 caaagcttct tttgcttggt cagccaatgc agtaaatgct gctgcatcgt taacagccaa
      781 gtcagctaac attttacggt tgatgtcgat ttcagcaact ttcaaaccgt gcattaattt
      841 tgagtagctc aagccattca tacgagctgc tgcgttgata cgagcaatcc acaatttacg
      901 gaagtcgcgt ttcttttgac gacgatcgcg atatgcgtag ttgtatgaat tcattacttg
      961 ttcttttgct gttttaaata aagtgtgttt tgaaccgtag taaccttttg ctaattttag
     1021 cactctttta cgacgtttac gagttactgt tccaccttta acacgtgcca tgtataattc
     1081 ctcctaataa aaataaatct tcagattctg ttatttgtac ttcttatttc atttttgcta
     1141 gttgttggcg aatacgtttg aagtcgccac tagaaaccat gcttgcttta cgcaattgac
     1201 ggcgttgttt ttttgttttg ccgtggaaac ggtgacttgt aaacgcgcgg aagcgtttca
     1261 atccgccttt accagtacgt ttgaaacgtt ttgctgatcc gcggtgtgtt ttttgttttg
     1321 gcatgactat atttcctcct caaaatcttt cgttatccga ctatcggctg tccaacagcc
     1381 agttagtcat tcaaattact tactgtcgtt tttcggtgcc agcgtcaaga acatgctgcg
     1441 tccgtccatt ttcgcttttt gttccactgt tgcaatatcc gcagtttctt cagctaagcg
     1501 attcaagact ttttgaccaa tttctttatg ggtaatggca cggcctttga aacggataga
     1561 agctttcact ttatcgccct tttccaagaa cttacgtgca ttacgaagtt ttgtattgaa
     1621 gtcattcaag tcgatcgtag gacttaagcg aacttctttt acattgatca ctttttgttt
     1681 tttacgcgct tcgcggtctt tcttttgttg ttcgaaacgg tatttaccgt agtccatgat
     1741 tcgcgcaact ggtggtttcg caccaggggc aactaacaca agatccaagt ttgcttgttc
     1801 tgcaatattc aatgcttctg cttttgtctt aactcctaat tgctcaccat ctgaaccgat
     1861 caatcgtaac tctcgtgcac gaatgccgtc gttaaccatc atatcctttg ctatggtcat
     1921 tcacctccaa atattatgag agaaagaaaa gcttaccgaa taaacggcaa taaaaaaacg
     1981 agttctctta cagaacccgc gcgtacttca cctaatagaa ccagtgaaaa ctatctagcc
     2041 cagtgacatt atcaactaag gcgagaagcg ggtgcttctg cttttatttc tcaaccatta
     2101 tagtatagca aaaactaatc tttttgtcaa tgtttttcat acagtttgtc ttccttttct
     2161 gaaaatgatt agattagcag gctttctagc agtgattccc gcttctttgc tatactaaag
     2221 aaaaacgagg tgaacccaca tgaaaaaaat cgaacctatt ccaccttctc ttcctcttct
     2281 tacaaaggga gagttttatt tagaagatga ggagatcttc tctggtcttc tgatcaacgg
     2341 aggtaaccaa agctatctcg atgccaaaaa tatggtatta agagagagtc atatccaaaa
     2401 acttacgatg caaaaaacag gtttacgtca ttttgaatgc agtaatgtca tttttgaaaa
     2461 atgtgatttt tccaatctgg agtggattgg tggcagtttc caccaagtcg tgtttcatca
     2521 atgtaaatta acaggtacga attttgccga aagttatctt cgagactgta ctttcactga
     2581 ttgtattgct tcgatggctt cctttagtag tacaaacttg aaagctgtct ccttcgatca
     2641 ttgtcaatta gaagacagcg aattttatga ggtcacttgg aaaaaccttt ttttgtctga
     2701 caatcagtta accggttcga actggtttcg aacttctctg aagggattag actttacgac
     2761 taatttcttc acaacaatcg ctttatctca agattctttg gcgggactaa tcgtcaatca
     2821 agagcaagca cttgtgatcg cccaagccct tggtttgcag atcaaagact agatcaacga
     2881 atccgccgcc acagtgcaat aagcatccaa atagataaga ccaaactgat gatcaaggcg
     2941 atttcccatc cgaaaacgga atgggtaaag ggtaactgga gattcattcc gaagaatcct
     3001 gtcacaatag ttggaacggt caagatcagc gaccagaccg tcaaaaattt catcgtgtca
     3061 ttcaagttgt tattcagcaa attattataa gtgccagaga gctggtctaa aatctgcgaa
     3121 gctaagttcg tcatttcaac tgcttgtcgt gcttcgatca gtgcatcgtc caactcttct
     3181 ttttcctttt ctgacaactt gcgataaata gccagtgcct tgatttgttc taaaagtact
     3241 acattttgtt ttgttcctgt aactaagtaa accaaaccga tctctaaatc tgaaagttgc
     3301 agcagattct tgttcgttgt tttttctctt aatttcagat taagccgctg acgttcacta
     3361 ttcacttcct cgattaaagg aaaaaaggaa tcagaaatca aaaacaatgt acgaaacaat
     3421 aaactgtata cactcatgtc tggcatccgt tccaaaagcg atcgaattag tcgaatcacg
     3481 tactcggtat tcggcgtggt aaatgtaaac aaaccgtctt cttttaaaat aaaagcgata
     3541 ggactagttt cataatgatt atcgactttt tgctggtgcg gaacatttga tacaagcagt
     3601 aacgcttcat caaaagaatc gtactctacg cgcgcccgtt catttttatc tagagaataa
     3661 gtcagcatct cgtcactaat gccatattct tcttttaagt ttttaacagc tagcacatcg
     3721 ttttgctgta cattgatcca aaaattacgg tcttgattaa aatagtgttt ttcccgcata
     3781 ctctatcctc ctgacatttg tttccagtat aaagaaaaaa gtcgctcaaa taaaggttta
     3841 ccctttattt gagcaactgt aaatcaaatg gatactttgg tttggcgaat ctctgctaat
     3901 ttttcttcga tcattttcaa gacttcttct tttgcttgag gatcttccac aaaattatag
     3961 cggtctccat cgatttggat ttttggactt tctttgtatt cttcatacca ttgatcataa
     4021 cgtctgttca attctttgta ataatcgtat agacttgggt caaaggacaa ttgttcatac
     4081 gaacgaccac gtttttcgat acgctctaac atcgtatcaa aagatacacg aatatgaact
     4141 aataaatccg gatgtttttt atgggcagca tagggaagtt cttccatcat gttttccagc
     4201 agttcatcat acacacaaac ttctgtttct gttgctcttc ctagatctgc atttagatgg
     4261 aaaagcagtg aatcttcata aatcgaacgg tccaatacat tattgtcatc tttcattgct
     4321 tgtttgatgc ttgcaaaacg tttattcaaa aaataaattt gcagcaaaaa agcatactgt
     4381 tcagggtttg cataaaataa gggcaagact tcattatcat caatcgattc ataaaatgcc
     4441 tgactatcaa agtgttcagc catcatttct gttaaacttg attttccggc accaattgta
     4501 cctgctaaaa cgatcacgct catttacctc cagctcactt catcactaaa tattgtgttt
     4561 aactccaacc ttttttaaat atacccccaa tatctagtag tgtcaattgt attttttcta
     4621 gtcaaagaag aaaaaaagtc aaaaaattct taagaaaaaa gtgttttttc tttagaaaac
     4681 gtattcttag ttttacttct gagatggttt tagtaaaata aaggaggaat gttttttgag
     4741 acccttagtg gacaaaaaaa ttcgtgaagc agcgcaactc gttttgggcg ctttattttt
     4801 tgcttaaaaa tcacttttac gtgagaagga gttagattat ggcaaactat ggccaaggag
     4861 aatcaagcgg aaagatcata ttgatgggcg agcacgcggt tgtttatgga gaaccagcga
     4921 ttgcctttcc tttctatgca acaaaagtca ccgcattcct tgaagagctg gatgcaatgg
     4981 acgatcaact ggtttcttcc tactattcag gaaatttagc cgaagctcct catgcattaa
     5041 aaaatatcaa aaaattattc attcacttaa aaaaacagca tgacatccaa aaaaacttgc
     5101 aactgaccat tgaaagcacg attcctgctg aacgtggaat gggatcaagc gctgcagtcg
     5161 ccacagcagt cactcgtgct ttttatgatt acttagcatt tcctttgtct cgtgaaatac
     5221 tattagaaaa tgtccagctt tcggaaaaaa tcgcccacgg taatcctagt ggaatcgatg
     5281 cagccgctac tagcagcttg cagccgattt attttacaaa agggcatcct tttgactact
     5341 tttctttgaa catcgatgct tttttgattg tcgctgatac aggaatcaaa ggacaaacaa
     5401 gagaagccgt caaagatgtc gctcacctct ttgaaaccca gcctcatgaa actggacaaa
     5461 tgatccaaaa attaggatac ttgacgaagc aagcaaaaca agcaatcatt gagaattcac
     5521 cagaaacgtt ggcacagaca atggatgaat cacagtcact tctggaaaag ctgacaatca
     5581 gcaatgattt tcttaatcta ttgatccaaa cagcaaaaga taccggggca ttgggtgcca
     5641 aattaactgg cggtggacgc ggtggctgta tgattgcatt agcacaaaca aaaacaaaag
     5701 cccaagaaat cagtcaagca cttgaagatg cgggtgctgc tgaaacttgg atacaaggat
     5761 taggagtaca tacctatgtt taaaggcaaa gcacgcgcat ataccaacat tgctctaatc
     5821 aaatattggg gtaagaaaaa tgaagaactc atccttccaa tgaacaacag cctttcgtta
     5881 acattggatg cattttatac agagacagaa gtcatctttt ctgatagcta tatggtagat
     5941 gaattttatc tagatggcac cttacaagac gaaaaagcaa caaaaaaagt cagtcagttt
     6001 cttgaccttt ttcgtaaaga agccggcctc tcactaaaag cttcagtaat cagtcagaat
     6061 ttcgttccta ccgcagctgg attagcctcc tctgccagcg ggctagctgc tttagcagga
     6121 gcttgcaata ctgctcttaa gcttggatta gacgatctct ctctttcaag atttgctcga
     6181 cgcgggtctg gttcagcttg ccgaagtatt ttcggtggtt tcgttgaatg ggaaaaaggc
     6241 catgacgact taagttctta cgctaagcca gtcccttccg attctttcga agacgattta
     6301 gcaatggttt tcgttttgat caacgaccag aaaaaagaag tgtccagcag aaatgggatg
     6361 cgtcgaacag tcgaaacatc cagtttttat caaggctggt tagattccgt tgaaggggat
     6421 ctatatcaat tgaaacaagc aatcaaaaca aaagatttcc aacttctcgg agaaacgatg
     6481 gaaagaaacg gactaaaaat gcatggaacg actttagctg cccagcctcc attcacttac
     6541 tggtctcctg acagcttaaa agcgatggat gcggtgcggc aattgagaaa aaaaggcatt
     6601 ccatgctact ttacgatgga tgctggccct aatgtcaaag ttttagtgga aaacagccat
     6661 ttatctgagg tacaagaaac atttaccaaa ttatttagca aagaacaagt aattactgcc
     6721 catgctggtc caggaattgc gattattgaa taaagggaga tttttatgat tgaagtatct
     6781 gcaccaggca aactctatat tgccggagaa tatgcagttg ttgaaacagg acatccagca
     6841 gttatcgctg cagtcgatca attcgtaaca gtcactgtag aatccgcacg aaaagtcgga
     6901 agtatccaat ctgcacaata tagtgggatg cctgtacgtt ggacaagacg caacggagaa
     6961 ttagttttag atattcggga aaatcctttt cattatatcc ttgctgctat tcgtttgact
     7021 gaaaagtatg cacaagaaaa aaacattctt ttatcctttt atgatctgaa agtaacaagt
     7081 gagttagaca gttcaaatgg ccggaaatat ggattgggtt ctagcggtgc cgtgaccgtt
     7141 gcaacggtca aagccttgaa tgttttttac gcgttgaatt tatctcaatt ggagattttc
     7201 aagattgcag cactagccaa tttagcagtt caagataatg gttcctgcgg cgacatcgct
     7261 gctagctgtt atggtggctg gatcgctttc tcaaccttcg accatccttg gctccaagaa
     7321 caagaaactc agcattctat cagtgagtta cttgccctgg attggccagg tctatccatt
     7381 gagccattga ttgctcctga agatttacgt ttattgattg gttggacggg tagccctgcc
     7441 tctacttctg atttggtcga tcaagttcac cgttcgagag aagacaaaat ggtggcttat
     7501 cagcttttct taaaaaacag tacagaatgt gtcaacgaaa tgatcaaagg gtttaaagaa
     7561 aataatgtaa cgttgatcca acagatgatt cgaaaaaacc gacaattact gcatgattta
     7621 tctgcaatca ctggggtcgt catcgaaacg cctgctttga acaaattgtg taatttagct
     7681 gaacagtatg aaggagccgc aaaatcttct ggtgcaggtg gtggcgattg cggaatcgta
     7741 attgttgacc agaaatctgg catccttcct ttaatgagtg catgggaaaa agcagaaatc
     7801 actccactgc cgttacatgt ctatagcgat caaagaaagg aaaaccgatg aatcgaaaag
     7861 acgaacatgt ttcactagct aaagcctttc atgataaaca aaaaaacgaa tttgacttcg
     7921 tacggatcat ccataaccct ttgccgcaaa tagcagtttc tgatgtcgat ctaagtacac
     7981 aggcagttgg gtttacacta agcagcccat tttatatcaa tgcgatgact ggcggaagcg
     8041 aaaaaacaaa aaaaatcaac caagatcttg caatcgtcgc aagagaagca gatttgatga
     8101 ttgccactgg ttcagtcagc gctgccttga aagacccttc tttagccgat acttatacga
     8161 ttatgcgaca agaatatcct cacgggaaaa tcattgccaa catcggtgca gggacttctg
     8221 tcgaaagagc ccaagaagct atccgattgt ttcacgcaga tgccttacag attcatttga
     8281 atgcacctca agagttggtt atgcctgagg gagaccgtga ttttaccaat tggaaagtac
     8341 ttattcaaga gactcaaaca gccattgacg tccccctcat cgtaaaagaa gtcggttttg
     8401 gcatgacaag agaaacgctc aatgatctag ctgctttagg agttcataca gttgatatca
     8461 gcggtcgaag cggaacaagc ttcacccaga tcgaaaacgc ccgtcgctcc aagcgggaac
     8521 tgagttattt agctgactgg gggcaatcga cagtctcttc attgcttgaa gcaaatgaag
     8581 cagacacttc tatggaaatc ctagcctccg gaggtatccg caatgcctat gacatattta
     8641 aagccctttg tctcggcgca aatgcagtgg gtacttcagg aaccgtactg acgcatctga
     8701 tgaatcacgg cgtagaagaa actattatac tgatgaagca atggcaagaa gagcttcgtc
     8761 tgctttatac tatggtcggc gcaacgaata ccgcggccct acaccaacaa tcactgatct
     8821 tttccggacc agtgaaggat tggtgcgaag caagagggat cgacttagtg aagtatggaa
     8881 gacgcacaga aaagagcgtg ggacaaaagt aaagaacact tttatcccac gctctaaaca
     8941 cgtataaacg gcggaagcaa aagcaactcc ttcggaaata agctgaaatt cacaaaaatt
     9001 tgaaaagcaa ttttcgtgaa ttccttctta tttcttggag ttaaacgctt ctgtcccagc
     9061 ctcttttttc gaataaatga tgtttaatca gctgtccttc ggtattcgtt caagccgctg
     9121 atttcacaac ctctccacta aacggtgtac taaagctctt ttaaggttgt tttccgatat
     9181 aggcaagtat gcctccgtcc acatacaaga catggccgtt aacgaaatca gatgcgctag
     9241 aagccaagaa gacagatggt ccagccaaat cgattggctc gccccagcgt gctgctggcg
     9301 tacgtccaac gataaattga tcgaatggat gacgttcacc gttttcttgt gtttcgcgta
     9361 atggagcagt ttgcggtgta gcaatataac ctggtccaat tccattacat tggatattgt
     9421 attgaccgta ttcagaagcg atgtttttcg tcagcatttt taatccgcct tttgccgcag
     9481 cataagcact gaccgtttcg cgtcctaatt cactcatcat ggagcagata ttgatgattt
     9541 taccgccgcc tttttcgatc atatcccgaa taactgcttt tgaaacgatg aatggggcat
     9601 ttaaatccac gtcgattact tggcggaagt ctgccgcatc catttcgatc atcggtgtcc
     9661 gtttgatgat ccctgcattg ttgactagaa tatcaactga acctacatct tctttgatct
     9721 gttgaaccat cgcttgaacc gcttcttcat cggtcacatc gcagacataa ccttttgcat
     9781 cgatgcctgc ttctttataa tgcgctatac cttcatcaac tgattcttga ttcaagttat
     9841 taaatacgat ttttgctcct gctgtagcta aagagcgtgc aatctcaaat ccaataccat
     9901 agacagcacc ggtgactaat gctacttttc catctaaacg aaacatatcc atactaaatt
     9961 ccatcatttt ctctccctta tgcttatttt aattgatcca tttgcaccat atccatgtct
    10021 gtataggtga tattttctcc gcacattgcc cagatgaatg agtaattgct tgtacctaca
    10081 cctgaatgga tcgaccagct tggcgaaata atggcttgtt cattgtctac gactaaatgt
    10141 tttgtttcat ctggtttgcc catcatatgg aacacacgtg tatcttcatt ggcataatca
    10201 aaatagacat aagcttccat acgacgttca tgtgtatgac aaggcatcgt attccaagca
    10261 cttcctggtt ctaaaatcgt ataacccatt tataaatgac agctatcgct gaagcttcta
    10321 ctgctgtaaa tatccccgtc aagataccac cgataatgat gacaatcaat agaaggctag
    10381 gaatcgcctc ttttattatt tttccagcat gagccatctg tcctttttcg acaacagggt
    10441 atttattctt tttagcaacg atgaatgcta ctagcatgat tcctagcgcc cacaaa
//
LOCUS       DAXQKX010000077        10279 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.079, whole genome shotgun sequence.
ACCESSION   DAXQKX010000077 DAXQKX010000000
VERSION     DAXQKX010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10279
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.079"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(63..230)
                     /locus_tag="ACF3MF_002388"
     CDS             complement(63..230)
                     /locus_tag="ACF3MF_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HFE3928321.1"
                     /translation="MYRPQYLEQKYEVITVHKGNGEKVYEYRRPIKSDTYKRKENNEV
                     IPLYGKRIAKH"
     gene            complement(426..590)
                     /locus_tag="ACF3MF_002389"
     CDS             complement(426..590)
                     /locus_tag="ACF3MF_002389"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928322.1"
                     /translation="MPATLNAYDGYDYRKKIVKKLYGATYGNVVSVLSVHHQASVTVA
                     EVEDAAVNGE"
     gene            1086..1361
                     /locus_tag="ACF3MF_002390"
     CDS             1086..1361
                     /locus_tag="ACF3MF_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928323.1"
                     /translation="MYKPYMISYDLNNPGQKYDKVFEIIKEFGAYIKLQKSFWLVKTN
                     LNPNQMCEKLNTVLDNNDSLFICELQKNYQGRATEENWKFINEHIFS"
     gene            complement(1358..1510)
                     /locus_tag="ACF3MF_002391"
     CDS             complement(1358..1510)
                     /locus_tag="ACF3MF_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928324.1"
                     /translation="MKLSVEGTPEEIQELLQAIGSSKEQKVSVSNSDIDGICNCLNRE
                     KISNPY"
     gene            complement(1819..2232)
                     /locus_tag="ACF3MF_002392"
     CDS             complement(1819..2232)
                     /locus_tag="ACF3MF_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family phage packaging/lysis
                     transcriptional regulator"
                     /protein_id="HFE3928325.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIETERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGKIIAYK"
     gene            complement(2309..2605)
                     /locus_tag="ACF3MF_002393"
     CDS             complement(2309..2605)
                     /locus_tag="ACF3MF_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928326.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKSKFKVGDMVRCEA
                     EEFVYPFRGYVKKILSNSAIIRIENTMKCDRSTAKHKHYLAVARLVDMEVIKSK"
     gene            complement(2602..3159)
                     /locus_tag="ACF3MF_002394"
     CDS             complement(2602..3159)
                     /locus_tag="ACF3MF_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HFE3928327.1"
                     /translation="MNKQEAIKKLESIKAIGNDAIAACYNESINSGITLMKKIDEPQK
                     PVIPQLVAGWLEKSTDPFTKAEKIAYLIKSKDGDSYYFCDWFVRDGIVTQEQGEELLA
                     WATRQSYETLLSLYNGYEVEKEPLWAIKNADGNYLTKCALWGKDGVNYSFECNPSHRL
                     LFTDKATADAAALLVNGTVEEVVER"
     gene            complement(3156..3575)
                     /locus_tag="ACF3MF_002395"
     CDS             complement(3156..3575)
                     /locus_tag="ACF3MF_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HFE3928328.1"
                     /translation="MIPKFRAWDKRKNVMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIDLMQSTGMKDKNGVDIFEGDIVLVSVRNGFDYLDNKVCIVKNSIDYSGLVCAT
                     VDEDLEYQIFNTELFEEYTYEVTGNIYENSELLEEQR"
     gene            complement(3572..3817)
                     /locus_tag="ACF3MF_002396"
     CDS             complement(3572..3817)
                     /locus_tag="ACF3MF_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928329.1"
                     /translation="MIKKLVQFSMDLYDIESGATLSVESDHLIINFGGKRQIILWVVD
                     DVLFPEIVHDFEESKAVEFEIVKKVMELIEKYEEDSE"
     gene            complement(3777..4133)
                     /locus_tag="ACF3MF_002397"
     CDS             complement(3777..4133)
                     /locus_tag="ACF3MF_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HFE3928330.1"
                     /translation="MDLITQYSDIILKKIMAKIQKDKKAKERAELVKLEMAETGVGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILEEYLR
                     RTANDKKTRSIQHGFI"
     gene            complement(4145..4270)
                     /locus_tag="ACF3MF_002398"
     CDS             complement(4145..4270)
                     /locus_tag="ACF3MF_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928331.1"
                     /translation="MGFFMAKILLFLGLVGAAYLVYALLSQTDDKEDDNNDEMKF"
     gene            complement(4272..5087)
                     /locus_tag="ACF3MF_002399"
     CDS             complement(4272..5087)
                     /locus_tag="ACF3MF_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005743 - mitochondrial inner membrane
                     [Evidence IEA];
                     GO_component: GO:0035632 - mitochondrial prohibitin
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prohibitin family protein"
                     /protein_id="HFE3928332.1"
                     /translation="MNENKLIKLGVAGAVIVGIGVIGGFKFFEKIDNGYVGVRYSMNG
                     GIKDEALTQGVKFVGIDKVIQYPIRLQTIQSKNISVSTSDGKKTTIDIKYDYKVDSTK
                     AAKMYKEFGNITSEDIESGWLKSKLQKVAREVYAKYSLLDVLSGDSSKVEAEVLTNFA
                     KSVESKGFEVEDVTLGVPDVDKETQKSIDAIIRAGQENEKAKLDAETAKTQADSEAYK
                     KTKAAEAEAESNRKVAESVTDNLIRYEEAQARKKHGWVTVNGADTVVTDEAGK"
     gene            complement(5098..5316)
                     /locus_tag="ACF3MF_002400"
     CDS             complement(5098..5316)
                     /locus_tag="ACF3MF_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr domain protein"
                     /protein_id="HFE3928333.1"
                     /translation="MIGLTIFWCAIGGLLAFLGYYLICESRKGRKYTVTGIVLLIIGI
                     LVAVGAELNLYVNGTQEDLVRFMFWMKN"
     gene            complement(5313..5624)
                     /locus_tag="ACF3MF_002401"
     CDS             complement(5313..5624)
                     /locus_tag="ACF3MF_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HFE3928334.1"
                     /translation="MNELITKVEQWAKDKGLDQADPKAQFLKVAEEFGEIASAMARSN
                     DELFKDSVGDVIVTLIILSMQKGTNVQECLEMAYNEIKGRTGKMVDGVFVKSSDLEDS
                     K"
     gene            complement(5621..5923)
                     /locus_tag="ACF3MF_002402"
     CDS             complement(5621..5923)
                     /locus_tag="ACF3MF_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928335.1"
                     /translation="MDKKAAMKRIAELTKSESWQEDKEIVAEVQKLGKSMWTEKPKRK
                     TPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEKK"
     gene            complement(5926..6087)
                     /locus_tag="ACF3MF_002403"
     CDS             complement(5926..6087)
                     /locus_tag="ACF3MF_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HFE3928336.1"
                     /translation="MTTEEVIQMRIRNIQREIDDLERTKAVMVNETARKAIDLHIENL
                     RRVIRRLEE"
     gene            complement(6102..6461)
                     /locus_tag="ACF3MF_002404"
     CDS             complement(6102..6461)
                     /locus_tag="ACF3MF_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HFE3928337.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQEK
                     FELMPKFELEGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQV
                     PLILAKKYRNTFKEERF"
     gene            complement(6458..7309)
                     /locus_tag="ACF3MF_002405"
     CDS             complement(6458..7309)
                     /locus_tag="ACF3MF_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFE3928338.1"
                     /translation="MESLASTMEKLIRRVLVQSGKCPECSEPLYSWRGKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALERAKSYVNDVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNAELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            complement(7327..8142)
                     /locus_tag="ACF3MF_002406"
     CDS             complement(7327..8142)
                     /locus_tag="ACF3MF_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HFE3928339.1"
                     /translation="MSDKQKKRYYWLKLKEDFFEEDTIEWLEEQPNGKEYCLFYLKLC
                     LKSLKTEGILVRNVGNLMIPYDPESLAKLTNSNTDTVKVAMDLFNKIGLIKILDSGEI
                     YLNQLSELVGSETEYARQKRIQRAKEDNVQKLSGKGRLEIELEKDIDIDIDKEEKKGK
                     YSDEHLRLAKKLQSNLTEDFPKEMNKVDIEKWADAIRLMEERDKASIEAIEYVINWLP
                     TNEFWFGNIRSAKKLREKFEKLKFEIKADKNNHKKQSQKLQYSNPSEYDDLPI"
     gene            complement(8161..8847)
                     /locus_tag="ACF3MF_002407"
     CDS             complement(8161..8847)
                     /locus_tag="ACF3MF_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative HNHc nuclease"
                     /protein_id="HFE3928340.1"
                     /translation="MFKPLIDSYSAVLKKFKGNDIDATINEEVNIERLKTMYDGYDGD
                     RIIEIRFIDPRRFTAQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     ETIKKLNIGG"
     gene            complement(8853..9587)
                     /locus_tag="ACF3MF_002408"
     CDS             complement(8853..9587)
                     /locus_tag="ACF3MF_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HFE3928341.1"
                     /translation="MSEGTKRNDNKLFNSLYKITVNDVVEKRNKLTYLSWAWAWAEVS
                     KICEEVDYEIYRDPETHRPYLFDEKTGYMVFTSITVNGVKRDMWLPVMDGANKAMKDE
                     PYTYEVNDYQWNNETKKKEIVGKIEKRVEAATMFDINKTIMRCLVKNLAMFGLGLYIF
                     AGEDMPEDVSMLEPATQRSKKLFLDALQLVANKYEKSIDEAIVALTDAASITADDSKW
                     TKRDLGILKRGVNWLEDQYREETKEK"
     gene            complement(9580..9921)
                     /locus_tag="ACF3MF_002409"
                     /pseudo
     CDS             complement(9580..9921)
                     /locus_tag="ACF3MF_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(10100..>10279)
                     /locus_tag="ACF3MF_002410"
     CDS             complement(10100..>10279)
                     /locus_tag="ACF3MF_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HFE3928342.1"
                     /translation="SKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEI
                     DQLNRQQRLFGDENE"
BASE COUNT         2646 a         2267 c         1600 g         3766 t
ORIGIN      
        1 tcaactgtaa tagccatcta tagaattcct cggtcatgtt ccgtctcctt tcgcaatctt
       61 atttaatgct tagctattct tttgccatac aatggaataa cttcattgtt ttcctttcgt
      121 ttatatgtat cgctctttat tggtcttcta tactcatata ctttttcgcc attaccttta
      181 tgaacagtga ttacttcata cttctgttct aagtattgtg gtctatacat tgttgtttcc
      241 tcctttgtgc aaaaataaaa agaccactca aagagtgatc taatatgtaa tagtaacttg
      301 cacgatgcac aaaacgcgta cgaaattgcg cacccctata tttttaaacc gccgatgcct
      361 cggttgctta aagtcgctgg agtgggattg caccactcac gagaacttac caggctctca
      421 cgaggctact cgccatttac cgctgcgtct tctacttccg ccacagtgac cgaagcttgg
      481 tggtgtacag atagcacact tactacattg ccgtacgtag caccgtatag cttcttaacg
      541 atcttttttc ggtagtcgta accgtcatag gcatttaatg tcgctggcaa ggaatcgaac
      601 cttgcatggt tgccgaagca ttgacctagc acacatgctt agcgtctacc ctttccgcca
      661 cagtgacact ataaaattat tcttggctgc tactattttt tattttgccc atttttaaat
      721 ccaatcatat agacattaag acagagcgca aaaattgaaa ttattaatgg aatcatttct
      781 cttcacccac ctttagttat cgtgtgaata attaaaaaac aatagacagc aacaaaataa
      841 cattgctttg ataatttggt ataaaccact ataaatttct tttcttgcaa ttatttttaa
      901 tatatgctag attatcaacc gatatagtca ctgcctgtac tagcggaaac tagtgcaggt
      961 tttttgttct atttactcaa aagttattac gataaattaa tattgtgaaa ataaatacta
     1021 agcgtataat tttatttatc agcgagtggt ccgctgaaat ataaaacaag gatgtgcaag
     1081 acaacatgta taaaccctac atgattagtt atgatcttaa taacccaggg caaaagtatg
     1141 ataaagtatt tgaaataata aaagaatttg gggcatatat aaagctacaa aaatcttttt
     1201 ggttagttaa aactaatttg aatccaaatc aaatgtgtga aaaattaaat acagtacttg
     1261 ataataacga ttccttattc atctgtgaac tgcaaaaaaa ttatcaaggt agagctacag
     1321 aggaaaattg gaaattcatt aacgaacata ttttctctta gtaaggatta gatatttttt
     1381 ctctgtttaa acaattgcaa ataccgtcaa tatctgaatt agaaacactt accttttgct
     1441 ccttgctact accaatagct tggagcaatt cttgtatttc ttctggagtg ccttctactg
     1501 ataatttcat ttttcttccc tccaatacat aaattaatag acagcagcag ttgaaagacg
     1561 acaagaacat gtttagtttt gtgagtgctg ctgtctaatc aaaataaaca gcaaccgatg
     1621 aagaatttag gaggagttga attcacatcc ttttcttcat aattagttgc tgtctatcta
     1681 agaagaagtt taaaacgatg agggagattg cctcccttcg tttattttgt cgatcctgtt
     1741 tcctaatctt tcgacactac cataataaca ctggtaaatg tctaaaaacc gccatcattc
     1801 cgccaaaaaa ccgccaaatt atttataagc aattattttt ccgtgtttat atgcttctgc
     1861 aaactctatt agagcttccg acttcatccg ttgtatactt ctttctgaat aacccacttc
     1921 acggctaatt ctgtagtttg agaagctatc tggcacacag aagctgtagt agagtatctg
     1981 acgactaatc agactaagag ccatcaaagc cgctagaatc gcatctctct ccgtttctat
     2041 atccatcatc tgaataatcg cgtcttctgc cttattgcca tgcttcggtg ccttcggcat
     2101 atccgttata atcggcgact taatatctat caaagagcga cctgccatcc gctccaaacg
     2161 ccgaaagttc ttcagcacat ctctcgcatt acatcttgtc tgtttgaaat ctacctctcg
     2221 taacaattgc atcaagtcaa accgctcctt tatgtgatat aataaatgtg ttggatttat
     2281 tgaatcagtc ggagcgatcc ggcttttttt atttgctctt gattacttcc atgtcaacta
     2341 atctcgctac agctaaataa tgcttgtgtt ttgcagtcga acgatcacac ttcattgtat
     2401 tttcaatacg aatgattgct gagtttgaca gtatcttttt aacgtatcct ctgaacggat
     2461 aaacgaactc ttctgcttca cagcggacca tgtcaccgac tttgaatttt gatttcttgc
     2521 gtgttttagg gttctttgtc ggcatatcta gcattaaacc gccgataccg tgactgctag
     2581 cgtaaaatcc gtcttttagt ttcatctttc taccacctct tccactgttc cattcaccaa
     2641 caatgctgca gcatccgctg ttgctttatc agtgaaaagc aatcgatgag atggattgca
     2701 ttcaaaacta taatttactc catcttttcc ccataaagca catttagtaa gatagtttcc
     2761 atcggcattc tttattgccc ataacggctc tttctcaacc tcgtagccgt tgtataggct
     2821 caatagtgtt tcatatgatt gtcttgttgc ccaagcgagt aattcttctc cttgctcttg
     2881 cgtcactatg ccatctcgta caaaccaatc acagaaataa tatgaatcac catctttaga
     2941 tttgattaaa tacgctattt tttcagcttt tgtaaaaggg tccgtagatt tctcaagcca
     3001 accggccacg agttgtggaa taactggttt ctgcggttcg tctatttttt tcattaacgt
     3061 aatacctgaa tttatactct cgttatagca agcagctatt gcatcatttc ctatcgcttt
     3121 aatactttct aactttttga ttgcttcctg tttattcatc gctgttcctc caataactcg
     3181 ctattctcgt atatatttcc ggtgacttcg tacgtgtatt cttcaaacag ctctgtgtta
     3241 aaaatttgat actctaagtc ttcatcaaca gtggcacaaa ctaatccgga ataatctatt
     3301 gaatttttga caatacagac tttattatct aagtaatcga agccatttcg cacgctgact
     3361 aatactatat ccccttcaaa tatatccaca ccattcttat ctttcattcc tgtggattgc
     3421 atgaggtcga tgtttcgcac atgatatgat ttcaattcgg taggatttat ccaatattca
     3481 ataaagtttg ttttgccgtt tttagtaaaa tgcaagacgg ctacatctct cattacgttc
     3541 tttcgtttat cccacgctct aaacttcggt atcattcgct gtcctcctcg tatttttcaa
     3601 tcaattccat tacttttttc actatttcaa actcaaccgc ttttgattct tcgaaatcat
     3661 gaacaatttc tggaaacagt acatcatcaa ctacccacaa aataatctgg cgctttccac
     3721 caaaatttat gattagatgg tccgattcca cagatagtgt tgctcctgat tcgatatcat
     3781 ataaatccat gctgaattga acgagttttt ttatcatttg ctgtcctcct caaatactct
     3841 tctaatattt ctttatactt ctctacaaat ttgaaacgat cttgatgaag tttcttgctc
     3901 caatttgttt gccgatccag ctcacgcatc tgatcgaacc ctttttgaat ttcgttgtaa
     3961 taaaattcaa tgtttgctgc tgctttccaa tgcctgctac ttcgcactcc tactcctgtt
     4021 tcagccattt ccaacttaac taattccgct cgttcttttg cttttttatc tttctgaatc
     4081 tttgccatga ttttcttgag gatgatatca ctgtattgtg taatgagatc cattatttct
     4141 cctcctaaaa tttcatttca tcgttgttgt catcttcttt gtcatcagtt tgggaaagga
     4201 gcgcatacac gagatatgct gctcctacta aacctaagaa caagagaatt ttagccataa
     4261 agaatcccat attatttgcc tgcttcatcc gtaactacag tatctgctcc atttactgtt
     4321 acccatccat gctttttgcg agcttgagct tcttcataac gaatcaaatt gtctgttact
     4381 gattcggcga ctttgcgatt agattctgcc tctgcttctg cagcttttgt tttcttgtaa
     4441 gcttcactat cagcttgagt ttttgcagtt tctgcatcta gcttcgcttt ttcattttct
     4501 tgaccagctc gaatgatcgc atcgattgat ttttgtgttt ctttatcgac atctggaaca
     4561 ccaagtgtta cgtcttcgac ttcaaaccct ttagattcaa ctgatttagc aaagttcgtt
     4621 aatacctcag cttcaacttt agaggaatct cctgaaagga catcaagcag actatatttc
     4681 gcataaactt cacgagcgac cttttgaagc ttagatttta accatccact ttcgatatct
     4741 tccgaagtga tattcccaaa ttctttgtac atttttgctg ctttagttga atcaactttg
     4801 tagtcatatt tgatatcaat cgttgtcttt ttgccgtcgc ttgtagatac tgaaatattt
     4861 tttgattgga tagtttgcaa gcgaattgga tattggatca ctttgtcaat ccctacaaat
     4921 ttcacacctt gcgtcagtgc ttcatctttg ataccgccgt tcattgaata gcgcacaccc
     4981 acatatccat tatcgatttt ttcgaagaac ttaaatcctc cgataactcc aatacctacg
     5041 attactgctc ctgctacacc taatttgatt aatttgtttt cgttcatttt tttcctccta
     5101 attcttcatc caaaacataa atcgcaccaa atcttcttgt gtaccattta cataaagatt
     5161 cagttctgct ccaactgcaa ctagaattcc gataattaac aggacaatac ctgtcactgt
     5221 atattttctt ccttttctac tttcacagat gaggtagtat cctagaaatg ctagtaaacc
     5281 accaatcgca caccaaaata ttgttaaacc tatcatttgc tgtcctccaa atcactcgac
     5341 ttcacgaata caccatctac catttttcct gtgcgccctt tgatttcgtt gtatgccatt
     5401 tctaaacact cttgtacgtt tgtccctttt tgcatggaaa ggataatcaa cgtgacgatt
     5461 acgtctccta cgctatcttt aaatagctca tcattacttc ttgccattgc tgaagcgatt
     5521 tccccgaatt cctcagctac tttcaaaaac tgtgcttttg gatctgcttg atccagtccc
     5581 ttgtctttag cccactgctc tacttttgtg attagttcgt tcattttttc tcctccacat
     5641 acctaaattg tcgtcctttt gaatcaatcc ataagctcct tgctctatcc cagatgatgt
     5701 ttttgctcag accagtaatt tcagataact gttcagcagt acctgttact agaattcggt
     5761 cgccatgcca gattgcaatt tttctcggcg ttttccgttt aggcttttca gtccacattg
     5821 atttaccgag cttttggact tctgcaacta tttctttgtc ttcttgccaa gattctgact
     5881 tggttaattc agcaattcgt ttcattgctg ctttcttatc cacgtttatt cctccaatct
     5941 acgaattacc cttcttaaat tctctatgtg caaatcgatt gcctttctag ccgtttcatt
     6001 gaccatcact gcctttgtcc gttccagatc gtcaatttca cgctgaatgt ttcgaattcg
     6061 catttgaatc acttcttctg ttgtcatgat ggaccacctc gttaaaaacg ctcttccttg
     6121 aacgtattcc gatatttttt ggctaatatc aacggcactt gatattgatg acaaaacagc
     6181 tttgccttga tcttaaagtc ttttgtctgc atccctttaa catctacgac tttgacaagt
     6241 ttgccgtttt tataaaatgt gaagtcggga atatactcga tcttgcgata cttctttcct
     6301 tctagttcaa atttcggcat cagctcaaat ttttcctgaa gttttacttt ccagccgttc
     6361 gcttccgctt gccacaaggc tagatcgtaa tactctgctt ctgcgataga atcgaacttg
     6421 atacctcgat gaacagtctt tttattacgg tatttgttca tgcgatacta cctttcactg
     6481 gttttatgcg cttgtctgct gtttgttgga atttcagcgc ataaccttct gaatttttaa
     6541 atatcctaga aacaattctt tcgccgtagg cttctcttag ctcaggacca gataagtttg
     6601 ttgtgatgat cgttgctttg ttctgtctgg cttctaagag cgtgtttaac gtgttgtttg
     6661 taaactgcct actatttgat accccgctac ctagttcagc tccaatatcg tcaaaaacca
     6721 ccaaatcagt tgttttgata tcggctataa gcgatccttc aatttctttt ctcagttcag
     6781 cattgttata agagaacttt atttgctcta ataattcttg atagcttata aaaagtattt
     6841 tcttgtcata atttgagcgc tcaagtattt cccaagctgt cgccattgac aagtggcttt
     6901 ttccgcttcc tgatttccct gatagaatga aatgtgcagg atggttcagt aggacatcat
     6961 ttacatagct tttagctctt tctaaagcaa ttttcgtttc ttggtccact acgtgataat
     7021 tctccatttt gcatttaaac aaagttttat ctgttaatac cgaaccattt tgaaaaaaac
     7081 tcaacgctcg tgcttttaag ctgtcgttat atatccgttc ggtctgtata tcctctttca
     7141 cacgtaacgc tttataacca caactcatgc atgttggttt acaacgttct gacccgtcct
     7201 tatttttccc tcgccaacta tacaaaggtt cgctgcactc tgggcatttt ccactttgta
     7261 ctaaaactct tcttattagc ttttccatag tacttgctag gctttccatc agttgtatct
     7321 cctttgttaa attggcaagt cgtcatattc actaggattg ctgtactgta gtttttgact
     7381 ttgcttttta tgattattct tgtctgcttt gatttcgaat ttgagcttct caaatttttc
     7441 tctcaatttc ttagcacttc taatatttcc aaaccaaaat tcatttgtag gtagccaatt
     7501 gatcacatac tcaatcgctt ctatagacgc tttatctctt tcttccatca acctaattgc
     7561 gtctgcccat ttttcgatat ctactttatt catttctttt ggaaaatctt cagttaaatt
     7621 actttgcaac tttttagcaa ggcgtaagtg ttcgtcagaa tacttacctt tcttttcttc
     7681 tttatctata tctatatcta tatctttctc taactctatc tctaggcgac cttttccaga
     7741 caacttctgg acattgtcct cctttgctct ttggattcgt ttttgcctag cgtattcagt
     7801 ctctgatcct actaattcac ttagctgatt tagatatatc tctccgctgt ccagtatttt
     7861 tattagtccg attttgttga atagatccat agcgactttc actgtgtccg tatttgaatt
     7921 tgttagtttt gctagagatt cgggatcgta aggtatcatc agattaccta catttctaac
     7981 tagtattcct tctgtcttta gagatttaag acagagtttc agataaaata aacaatattc
     8041 tttaccattc ggttgttctt ccaaccattc gatggtatct tcttcgaaaa aatcttcttt
     8101 taatttaagc cagtaatagc gtttcttttg tttgtctgac acttcaatac caccttttcc
     8161 ttatcctccg atatttaact ttttgattgt ctcctggttt aacttgatcc ctttgatttg
     8221 atatttattt ttgaaattga tcacacctat cttgtgtttc tccgtgtgat gaatcctgca
     8281 gagtgctgca aatgtgtact ctgaatgatc aacttctttg cgctttcgtc ttcctagcgc
     8341 tttgtcaaag tgatcgatgt cagctcctgt tttgccacag atgcagcaga ctctttttgt
     8401 gatgcatttg tagaagtaat actcttgatt cgctggtaaa atctcatagc cttctttgaa
     8461 aggaatatga tgttcaaaga tgaaatctaa gataatattt gctaagacgt tggcatcact
     8521 cacagttgta ttagattcat ctttcaggct tattttgcgc cctgtgacac cttcgaaacg
     8581 gaagtagaag aattccttcc agaagtccgt tggcatgcct gtatcgataa aaatatcgcc
     8641 tatcagcgca tagatgaagt ttcgttgctg tgcggtgaac cgacgtggat caataaaacg
     8701 aatttcaatg attcgatcgc catcatagcc gtcatacatc gttttcagcc gttcgatatt
     8761 tacttcttcg ttgattgttg catcaatgtc gttaccttta aatttcttta gtaccgccga
     8821 gtatgaatct attagtggtt taaacactca tatcacttct cttttgtttc ttctctgtac
     8881 tgatcttcaa gccaattaac gcctcgtttt agaatgccca agtctctctt ggtccattta
     8941 ctgtcatcag cggttataga agccgcatca gtcaatgcaa caattgcttc atcaatcgat
     9001 ttttcgtact tgttagcaac cagttgtaaa gcatctaaga atagcttttt gcttctttga
     9061 gtagctggtt caagcatcga aacatcttct ggcatatctt cgccagcaaa tatatatagc
     9121 cctagcccaa acatcgctag attttttaca agacagcgca tgattgtttt attgatatca
     9181 aacatcgttg ctgcttcaac tcgcttttcg atttttccaa caatctcttt tttcttcgtt
     9241 tcgttattcc actgataatc attgacttcg taggtatatg gctcatcttt cattgccttg
     9301 tttgcaccat ccatgactgg taaccacatg tcacgcttta ctccgttgac tgtgatactg
     9361 gtaaaaacca tatagcctgt tttttcatca aagaggtatg gacgatgcgt ttctggatca
     9421 cgatagattt cgtagtctac ttcttcgcag attttgctga cttctgccca cgcccatgcc
     9481 caggacagat aagttagttt gtttcttttt tcgacaacat cattgacggt tatcttgtaa
     9541 agactattga ataatttgtt atcgttgcgt ttcgttcctt cactcatcaa attctgcctc
     9601 catttcagca atgtacttct tgcctggtcc gtaataagag atatcaatca agttatctct
     9661 gtcgtactcc tctagcgcat caatcaagcc atcttcgatg acatagatgt attcaggttt
     9721 tctggaccgc ttcgatagat gaataagata gacatgatcc taaatactca caaaatttcc
     9781 caaatcgtct tgatcacatg ctagttcttc atccgtcaaa agattgcgtc tgatttttcg
     9841 attgcttgtt tccttgatat tcgatttgcc ccaactagga tcagtcaaat attgatctag
     9901 agtggaaagt tcttttttca tgtggtaaca tctccttaga tgtattttct ttgtgactca
     9961 ttgctttggt cggctgagtc acttttttat ttgttgccat gctttttgct tatcaatatg
    10021 ttgttggctt aggatgcttg gtttattgtg tctccaccag cgattagcaa ttaccgtccc
    10081 tattcttagc gcttcagccc tattcatttt catcaccgaa aagtctttgt tgtctgttca
    10141 gttgatcgat ttccatgcgg atcgcagttt ctggtaacca catttcaata aatgaaacag
    10201 catcatcgaa tctcttacga ggtaactcgc catatcttgg gattgaaaag gtacgtttaa
    10261 attcagacca aaattttga
//
LOCUS       DAXQKX010000078         9964 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.080, whole genome shotgun sequence.
ACCESSION   DAXQKX010000078 DAXQKX010000000
VERSION     DAXQKX010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9964
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.080"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            8..81
                     /locus_tag="ACF3MF_002411"
     tRNA            8..81
                     /locus_tag="ACF3MF_002411"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:42..44,aa:Pro,seq:tgg)
     gene            101..173
                     /locus_tag="ACF3MF_002412"
     tRNA            101..173
                     /locus_tag="ACF3MF_002412"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:134..136,aa:Ala,seq:tgc)
     gene            201..274
                     /locus_tag="ACF3MF_002413"
     tRNA            201..274
                     /locus_tag="ACF3MF_002413"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:235..237,aa:Met,seq:cat)
     gene            288..361
                     /locus_tag="ACF3MF_002414"
     tRNA            288..361
                     /locus_tag="ACF3MF_002414"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:322..324,aa:Ile,seq:cat)
     gene            385..474
                     /locus_tag="ACF3MF_002415"
     tRNA            385..474
                     /locus_tag="ACF3MF_002415"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:421..423,aa:Ser,seq:tga)
     gene            487..560
                     /locus_tag="ACF3MF_002416"
     tRNA            487..560
                     /locus_tag="ACF3MF_002416"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:521..523,aa:Met,seq:cat)
     gene            579..654
                     /locus_tag="ACF3MF_002417"
     tRNA            579..654
                     /locus_tag="ACF3MF_002417"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:612..614,aa:Asp,seq:gtc)
     gene            656..726
                     /locus_tag="ACF3MF_002418"
     tRNA            656..726
                     /locus_tag="ACF3MF_002418"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:688..690,aa:Gly,seq:tcc)
     gene            740..813
                     /locus_tag="ACF3MF_002419"
     tRNA            740..813
                     /locus_tag="ACF3MF_002419"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:774..776,aa:Ile,seq:gat)
     gene            838..925
                     /locus_tag="ACF3MF_002420"
     tRNA            838..925
                     /locus_tag="ACF3MF_002420"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:872..874,aa:Ser,seq:gct)
     gene            947..1018
                     /locus_tag="ACF3MF_002421"
     tRNA            947..1018
                     /locus_tag="ACF3MF_002421"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:980..982,aa:Glu,seq:ttc)
     gene            1041..1130
                     /locus_tag="ACF3MF_002422"
     tRNA            1041..1130
                     /locus_tag="ACF3MF_002422"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1077..1079,aa:Ser,seq:tga)
     gene            1143..1216
                     /locus_tag="ACF3MF_002423"
     tRNA            1143..1216
                     /locus_tag="ACF3MF_002423"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1177..1179,aa:Met,seq:cat)
     gene            1235..1307
                     /locus_tag="ACF3MF_002424"
     tRNA            1235..1307
                     /locus_tag="ACF3MF_002424"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1268..1270,aa:Asp,seq:gtc)
     gene            1311..1383
                     /locus_tag="ACF3MF_002425"
     tRNA            1311..1383
                     /locus_tag="ACF3MF_002425"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1344..1346,aa:Phe,seq:gaa)
     gene            1388..1458
                     /locus_tag="ACF3MF_002426"
     tRNA            1388..1458
                     /locus_tag="ACF3MF_002426"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1420..1422,aa:Gly,seq:tcc)
     gene            1471..1544
                     /locus_tag="ACF3MF_002427"
     tRNA            1471..1544
                     /locus_tag="ACF3MF_002427"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1505..1507,aa:Ile,seq:gat)
     gene            1556..1627
                     /locus_tag="ACF3MF_002428"
     tRNA            1556..1627
                     /locus_tag="ACF3MF_002428"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1589..1591,aa:Glu,seq:ttc)
     regulatory      1816..1895
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SMK box riboswitch (SAM-III) riboswitch; SAM
                     riboswitches modulate the expression of downstream genes
                     in response to levels of S-adenosylmethionine; SMK box
                     riboswitch shares no known similarity to SAM-I and SAM-II;
                     Derived by automated computational analysis using gene
                     prediction method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            1893..3086
                     /gene="metK"
                     /locus_tag="ACF3MF_002429"
     CDS             1893..3086
                     /gene="metK"
                     /locus_tag="ACF3MF_002429"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HFE3928343.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            3216..4688
                     /locus_tag="ACF3MF_002430"
     CDS             3216..4688
                     /locus_tag="ACF3MF_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HFE3928344.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            4771..5559
                     /locus_tag="ACF3MF_002431"
     CDS             4771..5559
                     /locus_tag="ACF3MF_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFE3928345.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(5626..6294)
                     /locus_tag="ACF3MF_002432"
     CDS             complement(5626..6294)
                     /locus_tag="ACF3MF_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HFE3928346.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            6409..8121
                     /locus_tag="ACF3MF_002433"
     CDS             6409..8121
                     /locus_tag="ACF3MF_002433"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3928347.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            8124..9896
                     /locus_tag="ACF3MF_002434"
     CDS             8124..9896
                     /locus_tag="ACF3MF_002434"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3928348.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
BASE COUNT         2900 a         1781 c         2278 g         3005 t
ORIGIN      
        1 aattaaacgg gaagtagctc agcttggtag agcacttggt ttgggaccaa ggggtcgcag
       61 gttcgaatcc tgtcttcccg ataattataa atttaaacac ggggccttag ctcagctggg
      121 agagcgcctg ctttgcacgc aggaggtcag cggttcgatc ccgctaggct ccatttcatt
      181 taaataatga atatcttttt cgcggtgtag ctcagctggc tagagcgtcc ggttcatacc
      241 cgggaggtcg ggggttcgat cccctccgcc gcgattttta agagcctgga cctttagctc
      301 agttggttag agcagacggc tcataaccgt ccggtcgtag gttcgagtcc tacaaggtcc
      361 attgtggcgt tgtaagtttc atatggagga ttacccaagt ccggctgaag ggaacggtct
      421 tgaaaaccgt caggcgggta aaaccgtgca agggttcgaa tcccttatcc tcctttttca
      481 tattatcgcg ggatggagca gtctggtagc tcgtcgggct cataacccga aggtcgtagg
      541 ttcaaatcct gctcccgcaa ttaaaaacta aaaacactgg ttccgtggtg taggggttaa
      601 catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc gccatgcggg
      661 tgtagtttag tggtaaaacc acagccttcc aagctgttgt cgcgagttcg attctcgtca
      721 cccgctttta gttttttatg ggcctatagc tcagctggtt agagcgcacg cctgataagc
      781 gtgaggtcga tggttcgagt ccatttaggc ccattagtac aaaatcttat tggttttggg
      841 gaagtactca agtggctgaa gaggcgcccc tgctaagggt gtaggtcggg aaaccggcgc
      901 gagggttcaa atccctcctt ctccgtttca atattttgtt ttacctggcc cgttggtcaa
      961 gcggttaaga caccgccctt tcacggcggt aacacgggtt cgaatcccgt acgggtcatt
     1021 aatttaatat agttttacat ggaggattac ccaagtccgg ctgaagggaa cggtcttgaa
     1081 aaccgtcagg cgggtaaaac cgtgcaaggg ttcgaatccc ttatcctcct ttttcatatt
     1141 atcgcgggat ggagcagtct ggtagctcgt cgggctcata acccgaaggt cgtaggttca
     1201 aatcctgctc ccgcaattaa aaactaaaaa cattggttcc gtggtgtagg ggttaacatg
     1261 cctgcctgtc acgcaggaga tcgcgggttc gattcccgtc ggaaccgttt ggctcggtag
     1321 ctcagttggt agagcaatgg attgaagctc catgtgtcgg cagttcgatt ctgtcccgcg
     1381 ccattatgcg ggtgtagttt agtggtaaaa ccacagcctt ccaagctgtt gtcgcgagtt
     1441 cgattctcgt cacccgcttt tagtttttat gggcctatag ctcagctggt tagagcgcac
     1501 gcctgataag cgtgaggtcg atggttcgag tccatttagg cccatttatt ttattggccc
     1561 gttggtcaag cggttaagac accgcccttt cacggcggta acacgggttc gaatcccgta
     1621 cgggtcatgg aagatacttt ttgagtatct ttttcttttt atctgaaaga atgattttaa
     1681 aaagcttagc agagttatct ttatggatga ttgtgctaag cttttttgga cagttctaat
     1741 gtaaaatatt tttatatttt ttaagcaaaa aaatgaaaaa atacgagcag aaaactgttt
     1801 tatctgctat acttggttcg ttgcaagttc ccgaaaggat ccgcaggacg gagatgcctt
     1861 gtaaccgaat ttaactaggg ggaatcatta taatggtaga aagacactta tttacatcag
     1921 aatctgtttc tgaaggacat ccagataaaa ttgctgacca aatcagtgat gcaatcttgg
     1981 atgcaatttt aaaacaagat ccaacagcac gagtagcgtg tgaaacgtct gtaacaactg
     2041 gtcttgtttt agtatttgga gaaatatcta cgacggcata tgtagatatt caaaaagtcg
     2101 tacgggaaac aataaaagaa attggttata cacgtgcaaa attcggattt gatggagata
     2161 cagcagctgt attggttgcg attgatgaac aatctcctga tattgctcaa ggagttgatg
     2221 aagcacttga gatccgggat gaagataaaa aagacgtatt agatgagatt ggtgctggtg
     2281 accaaggttt aatgtttggg tttgctgtag atgaaacacc agaattgatg cctttaccaa
     2341 tcgctttgag tcatcgtctg gtacgacgct tggcagattt gcgtaaatca aatgaattaa
     2401 cgtatttacg tccagatgca aaatctcaag taacggttga atatgatgat caaggacaac
     2461 cggaacgcgt agatacaatc gttatttcaa cacagcatga tgatgcagta gataatgaaa
     2521 caattcgtca tgatgtcatc gaaaaagtag tgaaggaagt tattccagct gaattattag
     2581 atgatcaaac gaaatattat atcaatccga ctggccgatt tgtcattggt ggtcctcaag
     2641 gggatgccgg attaacagga agaaaaatca ttgttgatac gtatggcggt tatgctcgtc
     2701 atggtggcgg tgctttttct ggtaaagatg cgacaaaagt tgaccgttct gccagctatg
     2761 ctgcacgtta tattgctaaa aacattgttg cagcagggct tgctcgcaaa gcagaagtac
     2821 agctagctta tgcgattggt gttgctcaac ctgtttcgat ctcaatcaat actttcggta
     2881 ctggaacggt tccggaagaa gaactgattg ctgcagtgag agaaaacttc gatcttcggc
     2941 cagcaggaat catcgagatg cttgatttgc gtcgtccgat ttacaaacaa acagctgctt
     3001 acggtcattt tggtcgtaca gatgtagatt tgccttggga acatacggac aaagtagatg
     3061 cgttgaaagc aagtttagca aaataagtta tattcagctg gaacgatcgc caagtggtgg
     3121 ttgttccagc tttttttatg gcagttaacc tcttgaaaaa gatagtaatt atttatctat
     3181 ttttagatcc tgtcataatg aaagggagga ataagatgaa aaaagaaaca aatgttactt
     3241 tggtcacagt gagtattttc attgcaacgt tcatgacggc tattgaaggt acaatcgtaa
     3301 caaccgctat gccaacgatt gtcggttcat tacatggaat ggaaatcatg aactgggtat
     3361 tttcgattta tttgctgaca aacgctatgc ttactccgat ttacggaaaa cttgcggata
     3421 aagtgggacg gaaaccaatc tttatttttg ggacattatt gtttattatc ggttcgttat
     3481 tttgcggttt atctcaaagc atgattgggt tgattgctgc tcgtgcgatt caagggatgg
     3541 gtgctggggc aatgatgcca gtagctttga cgatcatcgg cgatctttat tctattgaaa
     3601 agcgagcaaa agttttaggt ttgaatagtt cagcctgggg gattgccagt gtttttggac
     3661 cgcttgcggg aggattcatc gttgaaacga tcagctggca ctggatcttt tttatcaatg
     3721 tgccgatcgg aattctatta attattttga tttggctata tttaaatgaa ccaaaaatca
     3781 tacatgagtc taaaccaatg gatatttttg gtagttttag tttgatggcc atgcttgtct
     3841 cattgctgtt agggttccaa ttattaggag acgaaggaat gagtccgctt gtttctgctt
     3901 tgctgctagg tagtatcgta atgttaggta tttttgtttt tgccgaaaaa agagctaaag
     3961 atcctgtcat catgatgcat ttattcaaaa atccactatt tgttgtggtc aacttggctg
     4021 cagcattggc tagtggtttt ttgatgggaa tcgatgttta tatccctatg tggatgcaag
     4081 gtgtattagg gctgaatgca gcaattggtg ggctggtatt agcaccatta tcactagtct
     4141 ggatggtcgg ttctttcctt gcaagcaagt ggatgactca aatgaaaact cattgggtct
     4201 tgagaattgg actactaatc gcagctattg ggggcgcttg gttgtatctt atgcctttca
     4261 gaagtaacta tttatggttt tttgctatat caacggtcat cggtataggc ttaggtgtga
     4321 ccatgactac ctcgactgtc agtgcacaaa atagtgtatc tcgtgaccag cttggtgtag
     4381 caacttcttt taatacgtta gttcgaacaa ttggtcaaac agtcatggtt tctatttttg
     4441 gtttattgat aaatggggta actaaacgag aacttgcagc agcaaattta acaaatgatg
     4501 cagatatcat gaataaactg gtgaatccac aaacggctaa atatattgat gcggatattt
     4561 tgttaccatt aagaaaaatt ctttatgatg ggttacattc cgtttatcta gttggcttgt
     4621 tactcgtgat cattgctttg gtcttaacgc ttttcgttca tgaaaaaagt ggtaaaataa
     4681 aacagtagtt tcggttaaga tatgtacgta gccgaatcat tcaaatttaa agttattcaa
     4741 aaataacttc ttactaagga aggcgaaaat atggcattta ttcaagcaaa tatttattcg
     4801 aatgtgttag aaatggaagt caatctaaat gtgatactac cgcaaacaac aaaaaaggtg
     4861 attggcacca gttcagagca agagacaacg gatatacctg ttttatattt acttcatgga
     4921 atgggtggca atcatagtgt atgggaaaga cgtacgtcga ttgaacgtta tgtagcaaac
     4981 tacggattag ctgtcatcat gccatctact gatcttggct ggtacacaga tacagtttat
     5041 gacatgaagt attggacatt cattgcagaa gagctacctg agatttgtca tgaattattc
     5101 ccgcaattaa caagaaaaag agaaaaaaca tatgccgctg gattatcgat gggcggatat
     5161 ggcgcgttaa aactaggcct tgcaaaatca gaaaatttcg cagcagtaat ctctctttca
     5221 ggcgctgttt ctgtaggaaa tcgaatggat gatcttttga tggttcgtaa agcatctttt
     5281 tgggaaggga tctttggacc attggatcaa atcgaaggtt caaaaaatga tccgcaatac
     5341 ttattgaaag aactagtaaa aagcggaaaa ccagttccaa gattttatat ggcttgtggg
     5401 gaatctgatt ttctttatca ggcaaatcag gaaatggtat ctgctatgca ggaacaaggc
     5461 ttggcggtca cctttgaaca aggacctggc gatcataact ggatcttctg ggaccaatgg
     5521 attcaacgtg cattggcgtg gctaatggaa gaaaaataaa aaaagagtct taaaaagata
     5581 gctcctatag agatcacaaa catagtgatc tctataggag cttttttact gctcgttttc
     5641 tcttctttta ttttgttggc ataagccttc aatataggtt tgtgcactcg ttagaaagag
     5701 tgctttttca ttcaattctg catgggactg catactttct ttaaatccct ctaattgatt
     5761 ttcaactaca taattacgca taaatagaac tgtttctttc aaaaattcat ttccgtccat
     5821 aattttttgt cgaagctgct gttcatgctg ctgatccatt aactgtccaa tcaataaatt
     5881 gtggagagag gcaatggcct gatgactttg ggtgactgaa aatccttcac gaacaagtaa
     5941 ttggatcatt tgctccaaat gttctaatcg actcggaaaa gcgggcacag tattgatttc
     6001 taattctgcc ccacaaggga aacgtgtata aaggtcatag taattttcca tatactgcag
     6061 caactgttca ttccaaggca aagttggatc tggaagcgct aattcttctt ccattgtttc
     6121 agccattttt tgcaagagct gttgtttgtt tttgaaatac caatataaag caggtgcttg
     6181 aacatgaatt ctgtttgcga tgtttcgcat ggaaagctgc gaaagagctt gtgtttcagc
     6241 caggatatca aaggcggcct gaatgatgat tgcttgagaa agctttattt ccattttatc
     6301 aacctcgtgt attgcattat ctttttaaac atggtaaatt gttagtcggt ctaattttac
     6361 agtgttaaat tagtcctgtc aatttaaaca aaggggtgta atcaacgaat gaaattaatc
     6421 ttacgacatg cgaaaaaata taaagtagct gtttttattt ccttgctgtc cgtagcagtc
     6481 atggttgcag cagcattatg gcaacctaag ttactacagc aagtattgga agctattatt
     6541 acagaagata atgatgaaat gaaaacaatt ggtatttacc tgatcagtct ggctttgcta
     6601 ggattagccg caggtgtaac gaacacgatt ttctctgcaa aagtagctca aggcgtaagt
     6661 gcagatatcc gagaagaagc atttcgaaag atccagacat tttcatttgg aaatatcgaa
     6721 cagttctctg ctggaaatct tgttgttcgt ctaacaaatg atatcacgca aatccaaaat
     6781 ttagtgatga tttctttgca atcacttttt cgaattccat tcttatttat tggtgccttc
     6841 attttagcta tgatcacgat gccgcaatta tggtggatca tcgtagcgct tatcgttacg
     6901 gtatttctga ttacggcact ttcatttaca aggatgggca agcacttcat gatcattcaa
     6961 aaactgattg atcgtgtgaa tagcattgca aaagaaaact tactagggat tcgtgtagtg
     7021 aaatcttttg tacaagaaga aaaccaattg aagtcattca gcaaagtaag tgaggactta
     7081 acaaaacaca acatcatagt cggtacatta ttttctgtga tgatcccgtc cttcatgctg
     7141 gctgccaatt tggctgtggt tggggcgatc ttttttgtga gcgatcttgt taaagatgat
     7201 cctacgttaa ttggtggaat tgcttcattc atgaactact tgatgcagat tatgatggca
     7261 atcattattg gcggaatgat gatgatgatg acttcaagag cagccgtatc gctgaagcgg
     7321 attgcggaaa ttttagatgc tgaaccagat cttacttatt tagacgttcc agaacaagag
     7381 ttgacgggtt ctgtcacttt tgaccatgtt tcttttcgtt atcctggtga ggatacagat
     7441 acgcttaaag atatcagctt ttctatcaaa cctggagaaa tggttggtat cgtcggggcg
     7501 actggtgccg ggaagtcaac actagcacaa ttgatccctc gtctatttga tccgacagaa
     7561 ggcaaagttg aagtaggtgg tgtagatctt cgtcaagtaa atgaaaagag tttaagacaa
     7621 acggtttcct ttgttttgca aaaagcaatt ttattctcag gaacgattgc tcaaaacttg
     7681 cgccaaggga aaaagaatgc aacagaaaaa gagatggaac atgcttcttc tattgctcaa
     7741 gcaaaagaat tcatcgaaaa gttatctgat cgttacgaag caccaataga agaacgtagc
     7801 agtaactttt ctggtggtca aaagcaacgt ttatccatta ctcgtggcgt tatcggtaat
     7861 ccaaagatct tgatcctaga tgacagtacg agtgcactgg atgctcgctc tgaaaagctg
     7921 gtccgagaag cactcgatcg agatttgaag ggaacaacga cgattgtcat cgcacaaaaa
     7981 attgcttctg ttgtcaaagc agaccgcatc ttagtattgg atgaaggcag attagtcggc
     8041 gaaggaaccc atgaggaatt ggtagctgga aaccgtgtct atcaggaaat ctttgaaact
     8101 caaaaaggaa cggaggagta agtatgactg atctaataaa agcaagtaaa tttttctatc
     8161 actatttgaa gcggtacaaa ctctcctttt tctttatctt tatcacagtg atcattgcta
     8221 cctatctaca agtaaaggca cctcaataca tcggggaagc ttttcaagaa ttagctaatt
     8281 acgtaggagg cttgatgcaa ggcgtagacg ataaaagcaa atttgtttct gtaatatgga
     8341 aactcttgct gttttatgta ctagctagtg cagccaactt tatctatagt attttgttca
     8401 cacaagtagt agggaagtca acgaaccgaa tgcgtatcgg tctattcaac aaattggaaa
     8461 aattgacgat ccgtttcttt gattctcatc aagacggtga aattttaagt cgttttacca
     8521 gtgacttaga taatattcaa aatagtttga accaagcttt gcttcaagtc atcacgaatg
     8581 ctgttttact tgtcgggatc ttgatcatga tgttccgcca aaatgtagag ttagcttggg
     8641 ctacaattgc ttccactcca gtagccgttt tgatagctgt cttgattatc cgcaaagcac
     8701 ggaaatatgt ggatcttcag caagatgaag tggggaaact aaatggttat atggatgaaa
     8761 aaatcagcgg acaacgtgtc atcatcacaa atggcttaca agaagaaacg attgaaggat
     8821 tcttagagca taatcaaagt gttcgcgaag caaccttcaa aggacaagct tattctggtc
     8881 tactatttcc gatgatgcaa ggaatgtcac tggtcaatac agcgatagtt atctttttcg
     8941 gcggctggtt agcattaaat ggtgatttgg aacgttcggt ggcattaggc ttagttgtga
     9001 cattcgtcca gtattcacaa caatattacc aaccactgat gcagatttca tctggataca
     9061 gcatgatcca attagcgatt acaggggcaa gacgattgaa tgaaatattt gatgaaaaag
     9121 atgaagtcaa accagaaaac ggtaaagcat ttgatggtgt tgaaaaaggt cttgcgttgc
     9181 agcacgtaga ttttggttat tctccagaaa aactagtctt gaaagatgtc tcgatcaatg
     9241 tggacaaagg agaaatggtt gctcttgttg gtccaacagg atcggggaaa acgacgatca
     9301 tgaatctgct aaaccgtttt tacgatgtca atgatggttc agtagtcatc gatggaatag
     9361 atatccgaga ttatgatctt gatgcattac gtagacatgt aggaatcgtt ttgcaagaat
     9421 ctgtattgtt ctccggaacg atcaaagaca atatcacatt cggcaaaccg gacgcttcag
     9481 atgaagaagt catcaatgca gcaaaacaag cgaatattca tgacttcatc atgacgttag
     9541 aaaaaggtta tgatacagag atatccgaag aaaataactt attcagtaca ggtcaaaagc
     9601 agttgatcag tattgctcga acgatcatca caaatccatc tttattgatt ttggatgaag
     9661 caacaagtaa tgtagacacg gtaacagaag caaggatcca aaaagcaatg gatgaagcaa
     9721 tcaaaggaag aaccagcttt gtgattgctc accggctgaa aacaatcttg aatgcagata
     9781 gaatcgttgt cttgcgtgat ggggaagtca ttgaagaagg cagtcatcat gagttattag
     9841 cagaaaatgg attttatgcg gaactttatc ataatcaatt tgtatttgaa agttaaatta
     9901 aaagaacctc gttataacgg ggttcttttt atatatttta tgttgtttgt ttttataagg
     9961 ggca
//
LOCUS       DAXQKX010000079         9936 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.082, whole genome shotgun sequence.
ACCESSION   DAXQKX010000079 DAXQKX010000000
VERSION     DAXQKX010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9936)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9936)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9936
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.082"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            4..360
                     /locus_tag="ACF3MF_002435"
     CDS             4..360
                     /locus_tag="ACF3MF_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine-rich SFCGS family protein"
                     /protein_id="HFE3928349.1"
                     /translation="MIKVVIADRMGKGQNVAKGVEAAGGKAVVVPGMGADMRLGDVMQ
                     QEHADMGISFCGSGGAGALTAATKYGYPERHGMRSIEEGITAIKDGKTVLGFGFMDQE
                     ELGKRLTEEFIKKHGK"
     gene            376..726
                     /locus_tag="ACF3MF_002436"
     CDS             376..726
                     /locus_tag="ACF3MF_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4312 family protein"
                     /protein_id="HFE3928350.1"
                     /translation="MSVQKTIQQKVIVSGKGETKQHAFASALAEIQNKIMEQSNVLLR
                     IEPVNVDILKAVENKYTERFLFFFFPRQRISYEVELSVTVAVTEIKLADISFSQQMTE
                     DPNGIAIPFVTKKI"
     gene            755..1534
                     /locus_tag="ACF3MF_002437"
     CDS             755..1534
                     /locus_tag="ACF3MF_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4311 domain-containing protein"
                     /protein_id="HFE3928351.1"
                     /translation="MDFVIILVKSVIIGGLLGFAASVGAARMFHAPNTQGLGAFRTLG
                     EMNACMGDPASHFSFGLGFFFNAWASSVGAGAFTQDVTHRIIPNWAAAALLAKNKDVT
                     QTMHDPKKMGIIGAVIGAVVVAFLNTTAAAIPEALQVTAVSVLVPAATILINTVMPVI
                     FWLAALDAGKRTGFWGTLFGGIAQLIMGNAVPGVVLGILIGKGVDESGWNRVTKSMMI
                     AIVLLFIFSGFFRGFDMEMIKSFQLQVPNWLDNLHNIFSVK"
     gene            1545..2222
                     /locus_tag="ACF3MF_002438"
     CDS             1545..2222
                     /locus_tag="ACF3MF_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4310 family protein"
                     /protein_id="HFE3928352.1"
                     /translation="METTEEQAKVLEAKRQKSFWFADWSFPLIVGIMSAAVFAGTHMY
                     VMYGVGAFNEVSIVAMLKAGLDGGSYGAAAAFGASFLFARILEGSLVGILDLGGSILT
                     GIGIGVPAILLSMKIAAPIDNFALSLLTGLVLGLIVGGIIVLIRKFTINQSNSTFGAD
                     VMMGAGNSSGRFLGPLIILSACAASIPIGIGATLGALGFYAWKKPIAGGAILGAMILG
                     AIFPAVN"
     gene            2241..3347
                     /locus_tag="ACF3MF_002439"
     CDS             2241..3347
                     /locus_tag="ACF3MF_002439"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HFE3928353.1"
                     /translation="MFDTLIKNGRLVDGSKIEVAIEKGMIKAVAAEINQPAQEVVDLE
                     GKYYLSAGWIDDHVHCYEKMNLYYDYPDQIGVEKGVTTVIDAGTTGAENIREFYQLTK
                     SVKTNVYALMNISKWGIVKQDELADLTKIQEDLVSTALAELPEFIVGIKARMSKTVVG
                     ENGIKPLELAKKIQTENNDLPLMVHIGSAPPELEEVLSRMERGDVLTHCFNGKPNGIL
                     DPKTDQIKNFVWDAYNNGVVFDIGHGTDSFNFHVAETALKAGMKATSISTDIYIRNRT
                     NGPVFDLATTLEKLRVVGYSWEEIIEKVTAVPARNFHLKNKGQLAVNYDADLTIFEIV
                     ENEKELKDSNGFTRIAKEQILPIKTIIGGVIYDN"
     gene            3337..4428
                     /locus_tag="ACF3MF_002440"
     CDS             3337..4428
                     /locus_tag="ACF3MF_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HFE3928354.1"
                     /translation="MTISYGKFDLKEVINASGKMTILGVSKVSESVLAAQRFGGEHFF
                     EMSDLAIKTGAYLSQLLKVEDAQIVSSASAGIAQSVAALIGQGDMYHVYHPYTEKIAR
                     REIIIPKGHNVDYGTPVEVMVAQGGGKVIEAGYANMCTPEHVSMMITEKTAALLYIKS
                     HHAVQKSMLTVAEMVEVAKAHRLPLIVDAAAEEDLFKYSEMGVDLVIYSGAKAIEGPS
                     AGLVIGKKKYIQWIRLQSKGIGRAMKIGKDNILGFTQALEDYLKNGSESGDSMKQRLA
                     PFVNAINQLPDLSAKIVQDGAGRDIYRASVTINGDKSAKEVIQELKARNPAVYTREYQ
                     ANNGIIEFDIRSVSQNEMEKIIKRLREIM"
     gene            4441..5181
                     /locus_tag="ACF3MF_002441"
     CDS             4441..5181
                     /locus_tag="ACF3MF_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HFE3928355.1"
                     /translation="MSVIPNYYKNRVCLNVLAHSVENAKACYEAAEGHVVLGVLSKNY
                     ASDEAAIEDMKRYQDATNNALSVGLGAGDPNQSQMVSRLSGVLQPQHVNQVFTGVGTS
                     RALLGQNDTVINGLVSPTGKIGYVNIATGPLSSQAPAAEVPIETAIQMLQDMGGTSIK
                     YFPMKGLAHREEFKAVAEACAKYEFYLEPTGGIDLSNFEEILKIAIDAGVKKVIPHVY
                     SSIIDKETGDTRIGDVKILLSMVKKIIH"
     gene            5469..7409
                     /locus_tag="ACF3MF_002442"
     CDS             5469..7409
                     /locus_tag="ACF3MF_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HFE3928356.1"
                     /translation="MKKIIAITSCPVGIAHTYMAAENLEKAGKAVGAEVKVETHGSIG
                     IENELTARDIEEAAGVIIAADTKIDKSRFGGKPLITVGVQEGIHHADELVRDILAGKA
                     PVYKSTEAIISSENKSESENLGKKIYKSLMNGVSYMVPFVVTGGLLIAISLTLGGTAT
                     PEGIKIPEGTIWATMNSIGSIAMGLMVPILSAFIAQSIADRPGLVPGFVGGMLAANGA
                     LYGSDANAGFLGGIITGFLAGFIALGIKKVRVPKALQSIMPIIVIPILGSLAVGFVFI
                     YVIGEPVALLFSSLTHFLAGMQGGSEIVLAMILGAMIAFDMGGPFNKVAFLFGSGLIA
                     EGNYSIMGPIAVAICIPPLALGLASLILKTKFTKTEREAGKASLAMGLFGITEGAIPF
                     ASTDPLRVIPSIVIGAMTGSVIAMLSGVTDHVAHGGPIVAVLGAVDHVAMFFVAVIAG
                     IAVTVLMLRILKPTLQQTAVAAANGVTVADLSETETSDVYTKTETFDSITDIMSDEAI
                     VLGETATTKDGVIEDLVQRLEKTAAITDKTRFKEVIYDREHESTTGIGMGIAIPHGKS
                     AYVLKPTVAFARSQSGVDWHSLDGKPAHMIFMIAVPENSQGDMHLKILQRLSRKLMDD
                     DFRQALMEAPDKTTVHQLLSEM"
     gene            7496..9418
                     /locus_tag="ACF3MF_002443"
     CDS             7496..9418
                     /locus_tag="ACF3MF_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFE3928357.1"
                     /translation="MNQRQQSLIYQLSENNNYITTKKLAEHFHVSERTIHSDLNTIET
                     WLRDKHLPLMFERKKGTGILLNGLPHEREQLKRALNEETQTEMDKKQLRQLLIFHLLV
                     AKDGFSLEELSEKLYVGKRTIRKELTELQSFFEYHHLQLVSKTKLGTFLKGDEQEKRQ
                     LLVKTLRNMQKEDPQSPSLKEFFAKDTLKVIQHTLQDVFYENHLEQPNGLASVEIHIY
                     FMLERMKQYQKVKLSKDENEVVEHTQAQKLSSQILAKLATIYPIEFSPDEINYLALRI
                     ANLFTNSQAATRFQKESSALADHLIEQVEQFLGYSLKEDQLLKQNLRSHLSSTYFRLH
                     YGLQISNPLTKNVFSTYTQLFLVLQLILEDYFEKENFYVPQEETAYLTIHFQAAIERH
                     KHQKSRRYQTVLVSEYSKAMATFLEARLNRELPELTIMDLVEYKPELKRQDFPSVDFI
                     LATLPFKHISIPVIEISPMITETDLAYLTKYMLEHVPIKKKKTFDLASFTHPFLIFPQ
                     LERTDPADILNFMGNVLVEHHYVEPEFIDSVLERDSHSSTRVAPFVTIPHGNPLYVKH
                     SMISIATMKEPVLWHGEQIRIVLLLAIKKNDLKHAEFKKIFSVIHYLEKQPEQMAQLM
                     QSNHPLEILTLLSSYE"
     gene            complement(9698..>9936)
                     /locus_tag="ACF3MF_002444"
     CDS             complement(9698..>9936)
                     /locus_tag="ACF3MF_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HFE3928358.1"
                     /translation="SDLIDRDYFTQADLIITLCGDAKDKCPAVPNNHEHLHWDLKDPA
                     QAVGSEEEILTEFRKVREGIKRKVLDLNQRTSIV"
BASE COUNT         3240 a         1650 c         2208 g         2838 t
ORIGIN      
        1 atcatgatta aagtagttat tgcagaccgt atgggtaaag gacaaaatgt ggccaaaggg
       61 gtagaagcag ctggtggaaa agcagttgtc gtaccaggaa tgggggcaga tatgcgtttg
      121 ggcgatgtga tgcaacaaga gcatgcagat atgggtatct ctttttgtgg tagtggtggt
      181 gcaggtgcat taacagcagc aacaaaatat ggctatccag aacgacatgg tatgcgttcg
      241 attgaagaag ggatcacagc tatcaaggat ggcaaaactg ttctaggttt cggctttatg
      301 gatcaagagg aattagggaa acgtctgaca gaagaattta tcaaaaagca tggaaaatag
      361 aaagagggac atgaaatgag cgttcaaaag acaattcagc aaaaagttat cgtctccggt
      421 aaaggggaaa caaagcaaca tgcttttgca tcagcgttag cagaaattca aaacaaaata
      481 atggaacaat caaacgtatt attgcgaatc gaaccagtca atgtggatat tttaaaggcg
      541 gtcgaaaaca aatacacaga acgctttcta tttttcttct tcccacggca acgtattagc
      601 tatgaagtcg aactctctgt tactgtggct gtaacagaaa taaaattggc agacatatcg
      661 ttcagccagc aaatgactga agatccaaat gggattgcca ttccatttgt aactaaaaaa
      721 atctaatttt gaatcataag ggggaaagaa taacgtggat ttcgtaatca ttctagtcaa
      781 atcggtcatt atcgggggat tacttggttt tgcagcatct gtcggggcag ctcgaatgtt
      841 tcatgcacct aatacacaag gtttaggagc ttttagaaca ttaggcgaaa tgaatgcctg
      901 catgggtgat ccagcttctc atttttcatt tggtttaggc tttttcttta atgcatgggc
      961 ttcttcagtt ggtgctggtg cattcacaca agatgtgacg catcgaatca ttcccaattg
     1021 ggcagcggca gcacttctag caaaaaacaa agatgtcacc cagaccatgc atgatccgaa
     1081 aaaaatgggg atcattggag cggttatcgg ggcagtggtg gtagccttct taaacacaac
     1141 agctgcagca attccagagg cgttacaagt gacggcggtt tccgttttgg taccagcagc
     1201 gacgattctg atcaatacag taatgccagt tattttttgg ttggcagctt tagacgcagg
     1261 gaaacgaact ggtttttggg gcactctttt tggtggtatc gcgcaattga ttatgggaaa
     1321 tgcggtacct ggtgttgttc taggaatctt gattggtaaa ggcgtcgatg agagcggttg
     1381 gaatcgcgtc acgaagagca tgatgatcgc tattgtttta ttatttattt tcagtggatt
     1441 tttccgtgga tttgatatgg aaatgatcaa gagcttccag cttcaagtgc ctaattggct
     1501 tgataacttg cacaacatct ttagtgtgaa ataggaggag aatcatggag acaacagaag
     1561 aacaagcaaa agtattagaa gcaaagcggc aaaagagctt ttggtttgca gactggtctt
     1621 ttccgctaat cgtaggaatt atgtccgctg ctgtatttgc aggaacacac atgtatgtga
     1681 tgtatggtgt gggtgcattc aatgaagttt cgatcgtggc gatgttaaaa gccgggctgg
     1741 atggcggatc ctatggcgca gcggcagcgt ttggtgctag tttcttattt gccagaattt
     1801 tagaaggctc tttagttggg atcttggact taggcggttc gatcctaact gggatcggaa
     1861 ttggggtacc agcaattctc ttaagtatga aaatagcggc accaatcgat aattttgcac
     1921 tctctttatt gactggtttg gttctaggtt tgattgttgg tggcatcatt gtcttgattc
     1981 gtaaatttac gatcaatcaa tcaaattcca cttttggtgc tgacgtcatg atgggggcag
     2041 gaaattcatc tggacgtttt ttgggtccat taattatatt aagcgcgtgt gcagcatcta
     2101 ttccaatcgg cattggcgct acattaggag cactaggatt ctatgcttgg aaaaaaccaa
     2161 ttgctggagg tgctatttta ggagcaatga ttttaggagc aatcttcccg gcagtaaatt
     2221 aatagaaaga gggtcattaa atgtttgata ctttgattaa aaatggaagg ttagttgatg
     2281 gatctaaaat agaggtcgct atagaaaagg gcatgattaa agcagttgca gcagaaataa
     2341 atcagccggc gcaagaagta gttgacttgg agggaaagta ttatttatcc gctgggtgga
     2401 tcgatgatca tgtccactgc tatgaaaaga tgaatcttta ttatgactat cctgatcaga
     2461 taggggtcga aaaaggtgtg acgacggtca ttgatgctgg aactacggga gcagaaaaca
     2521 tccgtgaatt ttatcaattg acgaaatcgg tcaagacaaa tgtgtatgcg ctaatgaata
     2581 tctctaaatg gggcattgtc aaacaagatg aacttgctga tctaacaaag attcaagaag
     2641 atctagtaag tactgcgtta gcagaactgc cggaatttat tgtcgggatt aaagcgagaa
     2701 tgagtaagac agttgttggt gaaaatggca ttaagccatt agaattagct aaaaaaatcc
     2761 agacagaaaa caatgatctg ccattgatgg ttcatatcgg ttctgcacct cctgagttag
     2821 aagaagtatt gtcaagaatg gaaagaggcg atgtattgac ccattgtttt aatggaaaac
     2881 caaacggtat tttagatcca aagacagatc aaattaaaaa ctttgtctgg gatgcttaca
     2941 ataatggtgt cgtctttgat attggacatg ggacggatag ctttaatttc catgtggcag
     3001 aaaccgcact aaaagcagga atgaaagcta cctctattag tacggatatc tacatccgca
     3061 atcgtacaaa tggcccagtt tttgatctag caactacttt agaaaaattg agggtagtcg
     3121 gctattcttg ggaagaaatc attgaaaaag ttacagcagt tcctgcacgg aattttcatt
     3181 tgaagaataa gggccagtta gctgtcaatt atgatgcaga tttgacgata tttgagattg
     3241 ttgaaaatga aaaggaattg aaagattcca acggatttac acgtatagct aaagaacaaa
     3301 ttttaccgat taaaacaatt attggaggcg tcatatatga caattagcta tggaaagttt
     3361 gatttaaaag aagtcattaa tgcatcggga aaaatgacga tcctaggggt ttctaaggta
     3421 tctgaaagtg tcctagcagc acaacgattt ggaggcgagc atttttttga gatgagtgat
     3481 cttgccatca aaaccggcgc ttatctttct caattactga aagtggaaga tgcgcaaatc
     3541 gtttcttctg cttcagcagg gattgctcaa tctgttgctg ctttaatcgg acagggcgac
     3601 atgtaccatg tctatcatcc ctatacagaa aaaatcgcta gacgggaaat catcatacct
     3661 aagggacata atgtagatta tgggacaccg gttgaagtaa tggttgctca aggtggagga
     3721 aaagtcatag aagctggcta tgcaaatatg tgtacaccgg aacatgtttc catgatgatt
     3781 acggaaaaaa ctgctgcgct tctatatatt aaaagtcatc atgcagttca gaaaagtatg
     3841 ctgacggtgg cagaaatggt agaagttgcc aaagctcatc gtttgccatt gatcgttgat
     3901 gcagctgcgg aagaagattt attcaaatat agcgaaatgg gcgttgactt agtgatttac
     3961 tctggggcaa aagcaatcga aggtccgagt gccggactgg tcataggaaa aaagaagtat
     4021 attcaatgga ttcggctaca gtctaaaggt attggccgag caatgaaaat cggtaaagat
     4081 aatattttag gctttaccca ggcactagaa gattatttaa aaaatgggag cgaatccggt
     4141 gactccatga agcaacgatt agcgcctttt gttaacgcaa tcaatcaact tcctgacctt
     4201 tcagcgaaaa tagttcaaga tggtgccggc agagatattt atcgagcaag tgtaacgatt
     4261 aatggcgata aaagtgcgaa agaagtcatt caggaattaa aagcacgaaa tccagcagtc
     4321 tacacccgag aatatcaagc aaataacgga atcattgagt tcgacattcg ttccgtcagc
     4381 caaaacgaaa tggaaaaaat tataaaaaga ttgagagaaa tcatgtagga ggcttttaaa
     4441 ttgtcagtta tcccaaatta ttataaaaat cgtgtatgtt taaatgtatt agctcattca
     4501 gttgaaaatg caaaagcatg ctatgaagca gcggaagggc atgtcgtact aggtgtgcta
     4561 tcgaaaaatt atgctagcga tgaagcagca atcgaagata tgaaaaggta ccaagacgca
     4621 accaataatg cgttgtcagt tggattaggc gctggagatc caaaccaaag tcagatggtt
     4681 tcgcgtttat ctggggtttt acaaccacaa catgtcaatc aagtatttac tggcgtgggg
     4741 acttctcgtg ctttattggg ccaaaatgat acagtcatca atggattggt ttcaccaaca
     4801 ggtaagatcg gctatgtcaa tattgctaca ggtccgttaa gttcacaagc gccagcagct
     4861 gaagtgccta ttgaaactgc cattcaaatg ctgcaagaca tgggaggtac ttcaatcaag
     4921 tatttcccga tgaaaggctt agcacatagg gaagaattta aagcagttgc ggaagcttgc
     4981 gcaaaatatg aattctattt agagccaaca ggaggaattg atctttcaaa ctttgaagaa
     5041 attctgaaaa ttgcaatcga tgcaggtgta aaaaaagtga ttcctcatgt ttatagttca
     5101 attatagata aagaaacagg agatacgcgt ataggagacg taaagatact attaagcatg
     5161 gtaaaaaaaa ttattcacta actcattaga aaataagaag cttattccag aatgaaatta
     5221 aatggaataa gctttttata attaattacg gaaattgtta atgtagataa taatttagat
     5281 gtacgtaagc agaagtacag aaatgtaaga ttttccaata ttattttatt caacataata
     5341 aatcgtatat caattttttt agcgaaattt ctatttattc caagaatttc agttattacg
     5401 gaatcatttt gtgcttaata aaaagaaacc gtttttatat actataaatg tagaaaggcg
     5461 gtaggaaaat gaaaaaaatt attgcaatca catcctgtcc agttggtatt gcccatacat
     5521 acatggcagc agaaaactta gagaaagcgg ggaaagcagt tggcgccgag gtaaaagtcg
     5581 aaacacatgg ttccatcggt attgaaaatg aattgactgc aagagatatc gaagaagcag
     5641 ctggtgtaat catcgcagca gatactaaaa tagataaatc acgattcggc ggtaaacctt
     5701 tgataaccgt aggtgtgcaa gaaggaatcc accatgcaga tgagttggtg agagatattt
     5761 tagcaggaaa agcgccagtc tataaaagta cggaggcaat tatttcttcc gaaaataaaa
     5821 gtgaatcaga aaatttaggt aaaaaaatct ataagagttt gatgaatggc gtttcgtaca
     5881 tggtaccttt cgtagttaca ggagggttat tgatcgcgat ttctttaaca ttaggaggaa
     5941 cagctacacc tgaagggatc aagataccag aaggaacgat ttgggcaacg atgaatagta
     6001 tcggaagtat cgctatgggg ttgatggttc caattctatc tgcatttatt gcgcaaagta
     6061 ttgcagatcg tccaggactt gttcctggat ttgttggtgg gatgttagcg gcaaacggag
     6121 cattatatgg tagtgatgcg aatgcgggat tcttaggcgg gatcatcact ggatttttag
     6181 caggattcat tgctttagga atcaagaaag tgcgagtacc gaaagcttta caatcgatca
     6241 tgccaattat tgttatccca attttaggat cattggcagt tggttttgtg tttatctatg
     6301 ttattggaga accagtagct cttctattta gttcattgac tcacttttta gcagggatgc
     6361 aaggaggaag tgaaattgtt ctagctatga tcttaggagc gatgattgct tttgatatgg
     6421 gggggccgtt caataaagta gcctttttgt tcggatctgg cttgattgca gaaggcaatt
     6481 attccattat ggggccaatt gctgtagcta tctgtatccc tccattagca ttggggctgg
     6541 catcattgat tttaaaaacc aaatttacga aaacagaacg agaagctggt aaggcgtcct
     6601 tagcaatggg actgtttggg attacagaag gcgctattcc gtttgcttca acagatccac
     6661 tacgggtgat tccaagcatt gtaatcgggg caatgacagg aagtgtgatc gcgatgcttt
     6721 caggagtgac agatcatgta gctcatggcg gtccgatcgt agcggtttta ggagcagtgg
     6781 atcacgtagc catgtttttt gtagcagtga ttgctggtat tgctgtaacc gtgctaatgt
     6841 taagaatcct taaaccgaca ttacaacaaa ctgcggttgc tgcagcaaat ggtgtgacag
     6901 tagcagatct atcagagact gaaacaagtg atgtttatac gaaaactgaa acttttgatt
     6961 ctatcacgga tattatgtca gatgaagcaa tcgttttagg tgaaacagca acaacaaaag
     7021 acggagtaat cgaagattta gtccaacgtt tagaaaaaac agcggcgatc acagataaaa
     7081 ccagatttaa agaagtcatc tatgatagag aacatgaaag tacaacggga atcggtatgg
     7141 ggattgctat tccacatgga aaatcagctt atgttcttaa accaacagtg gcatttgcca
     7201 gaagtcaatc tggggtagat tggcattctt tagatggaaa acctgcacat atgatcttta
     7261 tgattgctgt acctgaaaac agccaaggtg atatgcactt gaaaatactg caacgtctat
     7321 cacgtaaatt gatggatgat gacttccgtc aagcactgat ggaagcgcca gataaaacaa
     7381 cagttcacca attattaagc gaaatgtaac ataagatgaa aaatcgaccg tgatgagaca
     7441 taatagatgt gttatcatga tcgatttttt atttagaagg gagtttctgc acattatgaa
     7501 tcagcgtcag caatctttga tctatcaatt aagtgagaac aataattata taacaacaaa
     7561 aaagctagca gagcatttcc atgtgtcaga aagaacgatt catagcgatt tgaataccat
     7621 tgaaacttgg ttgagagaca aacatctgcc tttaatgttt gaaagaaaaa aaggtacagg
     7681 tatcttgttg aatggtctgc ctcacgaaag ggaacaactg aaacgagcgc ttaatgaaga
     7741 gactcaaaca gaaatggata aaaaacagct tcgtcagtta ttgattttcc atctgctagt
     7801 agcaaaagac ggatttagtc ttgaagaact ttcagaaaaa ctatatgttg gaaaacgtac
     7861 gattcgtaaa gaattgacag agttgcaaag cttttttgag tatcaccatt tacagctagt
     7921 atccaaaaca aaactaggaa cttttcttaa aggcgatgaa caagaaaaaa gacagttgct
     7981 tgttaagaca ttacgaaata tgcagaaaga agatccacaa agtccgtcgt tgaaagaatt
     8041 cttcgctaaa gatacattaa aagttatcca acatacatta caagatgttt tttatgaaaa
     8101 ccatttagaa cagccgaatg gactggctag tgtggagatt cacatctact ttatgctcga
     8161 gcgaatgaaa cagtaccaga aagtgaaatt aagtaaagac gaaaacgaag tcgtggaaca
     8221 cacccaagca caaaagttaa gtagtcaaat attagcaaaa ctagccacca tctatccaat
     8281 tgaattttct cctgatgaaa tcaattatct ggctttgcgt atcgccaatc tttttacaaa
     8341 ttcacaagca gccacacgtt ttcaaaagga atctagcgca cttgctgatc atttgatcga
     8401 acaagtggaa cagtttctag gctattcatt aaaagaagat cagctactaa aacaaaattt
     8461 aaggtctcat ttatcttcaa cttattttcg actccattat ggtttgcaga tttctaatcc
     8521 attgacgaaa aatgtgttta gtacgtacac acaacttttc ttagttttac agttaatttt
     8581 agaagattat tttgaaaagg aaaattttta tgttccacaa gaggagacag cttatttaac
     8641 gatccatttc caagcagcga tcgagcgaca caaacatcag aaaagtagaa gatatcaaac
     8701 ggttttagtt agtgaatatt caaaagctat ggctactttt ctcgaagcac ggctgaacag
     8761 agaacttcca gaattaacga ttatggatct agttgaatat aagccagaat taaagagaca
     8821 agattttccc tctgttgatt ttatcttggc tacgttacca tttaaacata taagcattcc
     8881 agtaatcgag atctcaccaa tgatcacaga aactgatcta gcctatttga caaaatatat
     8941 gctggagcat gtgcctatca agaagaaaaa aacatttgat ctagcaagct ttactcatcc
     9001 atttctgatc tttcctcaac ttgaacggac agacccagcc gatattttaa actttatggg
     9061 aaacgtctta gtggaacatc attatgtgga gccggaattc atcgattctg tcttggaaag
     9121 agacagtcac tccagtacta gagtagcacc atttgtaaca atccctcacg gtaatccgct
     9181 gtatgtgaag cattcgatga tttctattgc tacaatgaaa gaaccagtcc tatggcacgg
     9241 ggaacagata cgtatcgtac tgctattagc aataaagaaa aatgatttga aacatgcaga
     9301 gttcaaaaaa atattttctg ttattcacta tctagaaaag cagccagaac aaatggctca
     9361 gttgatgcaa tccaatcatc cgctagaaat cttaacgttg ttatctagtt atgaataagt
     9421 agcgattaaa aaactgcctt tatatttata ataattctat ctatttattt ggaagtagaa
     9481 aactaaatac aaaaaaagag gatgtggcca aagttgtggc acatcctttt attttgagtt
     9541 tcttataatt ttttatagtt gcttacgatg tcttgactac tggtaaacgg tgttcaagag
     9601 acaatttgtc ggcaataagg cacaattttg taaaatatgg aaagctattt ttttaacatt
     9661 gtttcttagt gcttgaaaaa tcattttgaa tacttcttta tacgatcgat gtacgttgat
     9721 ttaagtctaa aacttttctt ttgattcctt ctctgacttt tctgaattcc gttaatattt
     9781 cttcttcgct cccgacagct tgtgcaggat cttttaggtc ccagtgaagg tgttcgtgat
     9841 tgtttggaac ggcagggcac ttgtctttgg catcaccaca aagtgtaatg atcaagtctg
     9901 cctgagtaaa gtaatctcta tcaatcaaat cagacg
//
LOCUS       DAXQKX010000080         9797 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.083, whole genome shotgun sequence.
ACCESSION   DAXQKX010000080 DAXQKX010000000
VERSION     DAXQKX010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9797
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.083"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            141..1187
                     /gene="gmd"
                     /locus_tag="ACF3MF_002445"
     CDS             141..1187
                     /gene="gmd"
                     /locus_tag="ACF3MF_002445"
                     /EC_number="4.2.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008446 - GDP-mannose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0019673 - GDP-mannose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="HFE3928359.1"
                     /translation="MKKALITGITGQDGSYLADFLLEKGYEVHGITRRASISNTARID
                     HLMGKITLHDGDLSDSSSLIRIISIVQPDEIYNLAAQSHVQVSFDVPEYSGDVDALGV
                     MRILEACRILGLTKKTKIYQASTSELYGKVEEVPQRETTPFHPYSPYAVAKQYGFWIT
                     KEYREAYGMFAVNGILFNHESERRGENFVTRKITLAAGRIAEGLQDHLELGNMDSLRD
                     WGYAKDYVECMWMILQHETPEDFVIATGEQHTVRDFTEKAFAANGMTIRWEGTGIDEK
                     GYDVETGKMLVCVNPQWFRPTDVDNLWGDPTKAKTVLGWNPQKTSYEELVNIMAKHDR
                     ELAKREAAMKNAVK"
     gene            1195..2280
                     /locus_tag="ACF3MF_002446"
     CDS             1195..2280
                     /locus_tag="ACF3MF_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016758 - hexosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFE3928360.1"
                     /translation="MNKHICFYLSSHGFGHIARNLPIIMATLCRCEAKITLVCGANHL
                     DFAKRNLEQELPKELIDRVRYRPINTDIGLINREGTLLVDTGKLTEICEYFLAKVPSL
                     AKTEAEWLKREAVSAVLCDMPIWAMDACDMAGVPFLYVGNFTWTELYREFLPEHIWKE
                     YAKRYGKIQHTMLYALNNEEMLEFLQNSEKTPTSVVARPIHNDEVQRIKSQHEKPPVF
                     VALGMSARFKQPIDVSHAPYDFITTLGVPLVGENVTVISNSTPNTQDYIAAADYVITK
                     AGWGTVAECILAQRPMALFARDTVLEDRTTICKLQKLGLAISVTPENLHRVERVIEDL
                     KQLDTSNFDTFYDAASEIADKLISLMQ"
     gene            2317..3261
                     /locus_tag="ACF3MF_002447"
     CDS             2317..3261
                     /locus_tag="ACF3MF_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014424865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-L-fucose synthase family protein"
                     /protein_id="HFE3928361.1"
                     /translation="MMEKDAKIYVAGHRGMAGSAIVRELNRQDYNNIITRTHKELDLC
                     RQDAVEAFFAQEKPDYVFLAAAKVGGIIANQNALADFMYENMILEMNVINSAWENGCK
                     KLQFLGSSCIYPRMAPQPMPESCLLTSELEKTNEAYALAKISGLKYCEFLNKQYGTDY
                     ISVMPTNLYGPNDNYHPTHSHVLPALIRRFHEAKEAGLPTVTCWGDGSPLREFLYVDD
                     LANLCVFLMNNYSGDETVNAGTGKELSIKELTEMVAKVIGYEGEILWDTSKPNGTPRK
                     LLDVSKATKLGWTYKTELEDGIRLSYEDFLNNPMRAER"
     gene            3329..4642
                     /locus_tag="ACF3MF_002448"
     CDS             3329..4642
                     /locus_tag="ACF3MF_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="HFE3928362.1"
                     /translation="MNIVLLSGGSGKRLWPLSNDIRSKQFIKIFKTEDGYESMVQRVY
                     RQIKKVDNDATVTIATSKTQVSAIHNQLGEDVGVSVEPCRRDTFPAIALATAYLVDVM
                     GIDPEESVVVCPVDPYVEDDYFEALKSLSDQADKGEANLVLMGIEPTYPSEKYGYIIP
                     ESAEQTAFVNTFKEKPSEAVAKEYIAQGALWNGGVFVYKLKYVMERAHQLIDFVDYQD
                     LFNKYDTLTKISFDYAVVEHEDKIQVQRFAGMWKDLGTWNTLTEGMEESIIGKGVMNE
                     NCDGVHILNELDVPVLAMGLHDVVICASREGILVSDKEQSSYIKPFVDKFEQQIMFAE
                     KSWGSYKVMDVEAESMTIKVTLNASHSMNYHSHKNRDEVWVVLAGTGKTIVDGYEQVV
                     KAGDVITMSAGCRHTIMADTELKLIEVQLGKDINVKDKQKFELEY"
     gene            4834..5628
                     /locus_tag="ACF3MF_002449"
     CDS             4834..5628
                     /locus_tag="ACF3MF_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I phosphomannose isomerase catalytic
                     subunit"
                     /protein_id="HFE3928363.1"
                     /translation="MTLTEVLQEHPEFLGTHPQTKGELPILIKFIDAKKDLSVQVHPT
                     DEYAIEKENGQLGKTEMWYVLDASLIYGLQKITEEAVIREAIAQGTVERYLQKVPVKK
                     NDVFFIEAGTIHAIGAGALIAEIQENSNLTYRLYDYDRVDKNGKKRELHVDKALEVAN
                     LKGLSEPKQPLRVLKYRAGVAAELLCRCKHFEVSRMIVNTERRQTVHYRADSISFRVL
                     LCVNGCGTVRFDNESLDIYKGDCLFVPADSTEISIHGSIQFLDVRG"
     gene            5633..7285
                     /locus_tag="ACF3MF_002450"
     CDS             5633..7285
                     /locus_tag="ACF3MF_002450"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HFE3928364.1"
                     /translation="MNYKVEYERWLNHANADIIEELRSYSEKDIEDSFYKNLSFGTGG
                     LRGTIGAGTNRMNVHTVGKASQGLADYLNKNYEAASVVVGYDSRIKSDVFAKTAADIF
                     AANGIQVHLWPELLPVPTVSFATRYLKADAGVMITASHNPSKYNGYKVYGADGCQITT
                     EAATAILAEIEKLDIFADVKMDGDASKIASIQSEVLTAFIEEVKGQSVLFGEEVDKNV
                     AIVYSPLNGTGLVPVTRTLAEMGYSNVTVVEEQRLPDGNFPTCPYPNPEIKEAMSLGM
                     EYAKKYNADLLLATDPDCDRVGIAVKSAHGDYVLLSGNETGLLLLDYICSQRIKHGKM
                     PADPVMVKTIVTMDLGERIASNYGVRTIDVLTGFKFIGEQIGMLEKAGKVDSYIFGFE
                     ESYGYLSGSYVRDKDGVNAAYLICEMFSYYKTQGISLLDKLNEIYTKYGYCLNTLHSF
                     EFDGAAGFTKMQEIMVEFHKGLDIIGGKKVIETLDYSKGLNGLPKSDVLKFMLEDNCS
                     VVVRPSGTEPKLKTYISVSAENKEAAEAMEAIMAAELAEMFE"
     gene            7309..8175
                     /locus_tag="ACF3MF_002451"
     CDS             7309..8175
                     /locus_tag="ACF3MF_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFE3928365.1"
                     /translation="MEELFSNALKSVKSNRVLYTASFFARSSLLYLQEIGQLTALKAH
                     TSRRTGLSSYLCFLVEVGSGTLEYKGQKYTLQVGDMVFIDCLKPYVHESSEDDLWTLR
                     WCHFNGIGMTEVYKKYLERGGQPVFKTSKTDKYADLLRSLHMVAEGQEYVRDMKINVL
                     LSELLMHLMEDSWNPDKVPNFSTKKMELQNIKQYLDDHYTEKITLDQLSAEFFINKQY
                     LAKIFRETYGTTVVGYLNQKRITQAKHLLRFTNLSMEEIATKIGITDANYFSRTFFKV
                     EGVRPSEFRKMW"
     gene            complement(8217..8408)
                     /locus_tag="ACF3MF_002452"
     CDS             complement(8217..8408)
                     /locus_tag="ACF3MF_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928366.1"
                     /translation="MIIRDDHIYTCDSCHYSFPADEQPERCPDCEKTATRLDTEIETE
                     DYYRVRAEIKAEIKALNAG"
     gene            8567..8977
                     /locus_tag="ACF3MF_002453"
     CDS             8567..8977
                     /locus_tag="ACF3MF_002453"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928367.1"
                     /translation="MEEIMQMILGNAKFQLGQVVSTPAVLETFNPLQTANGIPEALSN
                     LWFRQEISIAEIEDAVLDAKNGKELANSLNRIKLFRKFTLDRELDGMVRLKGTDVWKN
                     ISYLKVYTATPPKKPTPPRFQSNGWSLFFSHKSA"
     gene            9105..9458
                     /locus_tag="ACF3MF_002454"
     CDS             9105..9458
                     /locus_tag="ACF3MF_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928368.1"
                     /translation="MAMSEKAKKYLKEIKGAKTIPELKDVEIAIKRDGILAWAEFTKL
                     NEAVEEKKVALRKKKQETSLQEILFWAYKKESDKLLKMMDEGADKDAIQMQVQRYDSI
                     GQIIAEADLEDEYEV"
BASE COUNT         2719 a         2032 c         2483 g         2563 t
ORIGIN      
        1 cacgaaaaac taatattgtg ctaatgcgtg cgtagattgt tctatgaaat atcgaaaatt
       61 atcgtgtatt cttgaaaagt attagaaatt acgagccatt tatatggcct tatcacttac
      121 ataggaaagg ataatgtatc atgaaaaaag cgctgattac tggtattact ggtcaggacg
      181 gttcctatct ggcagatttc ctgctagaga agggctacga agttcacggt atcactcgcc
      241 gtgcttctat ttccaatacc gctcgcattg accatttgat gggcaagatc acccttcatg
      301 acggtgacct gtccgactca tcttctctga ttcgtatcat cagcattgtt cagcctgatg
      361 aaatctataa cctcgctgca cagagccatg ttcaggtttc ttttgatgtt cctgagtact
      421 ccggcgatgt tgatgctttg ggcgttatgc gtattctgga agcttgccgt attctgggcc
      481 tgacgaagaa gactaagatt tatcaggcat ctacttctga gctgtatggc aaggttgaag
      541 aagttcctca gcgtgaaacc actccgtttc atccttacag cccttatgct gttgcaaagc
      601 agtatggctt ctggatcact aaggaatatc gtgaagctta tggcatgttc gctgtcaacg
      661 gtattctgtt caaccatgaa tccgaacgtc gcggtgagaa tttcgtcacc cgtaagatca
      721 ccctcgctgc cggccgcatt gcagaaggcc tgcaggacca tctggaactg ggcaacatgg
      781 actccctgcg tgactggggc tatgcaaagg actatgttga gtgcatgtgg atgattctcc
      841 agcatgagac tcccgaggac ttcgtgatcg ctaccggcga gcagcacact gttcgtgact
      901 tcaccgagaa ggcattcgca gcaaatggca tgaccattcg ttgggaaggc actggcattg
      961 atgaaaaggg ctacgatgtt gaaaccggca agatgctcgt ttgtgtaaat ccacagtggt
     1021 tccgtccgac tgacgttgac aacctgtggg gcgacccgac taaggcaaag accgttctcg
     1081 gttggaatcc gcagaagacc tcttacgagg aactggttaa catcatggca aagcatgacc
     1141 gtgaattggc aaagcgcgaa gctgcaatga agaacgcagt caagtaagct gacattgaat
     1201 aaacatatct gtttctatct ttccagtcac ggcttcggac atatcgcgcg gaatctgccc
     1261 attattatgg caacactctg ccgatgcgaa gcgaagatta cactggtttg cggcgcaaat
     1321 catctggatt ttgcaaagcg caatttggag caggaactgc ccaaagagct gatagaccgc
     1381 gtgcgctatc gtccaataaa cacagatatc ggtctgatta accgtgaggg caccctactg
     1441 gtggacacgg gtaagctgac cgagatctgt gaatattttt tggcaaaggt tccttctttg
     1501 gcaaagacag aagccgaatg gctcaagcga gaagctgtca gcgcagtgct ttgcgatatg
     1561 ccaatctggg caatggatgc ctgcgatatg gcaggagtac ctttcctgta tgtaggaaac
     1621 ttcacttgga cagagctgta tcgcgaattt ttacccgaac atatttggaa agaatatgcc
     1681 aagcgttacg gtaaaattca gcacaccatg ctttatgcgc taaataacga agaaatgttg
     1741 gaatttctcc aaaacagcga aaaaacaccg acttccgttg tggcgcgtcc gattcataac
     1801 gacgaagtgc aacgcattaa atcacagcat gaaaaaccgc ctgtatttgt cgcactcggt
     1861 atgtccgcgc ggttcaaaca gccgattgat gtcagtcacg cgccgtatga tttcattaca
     1921 acgctaggtg ttccgcttgt gggagaaaac gtaaccgtta tttctaacag cacccccaat
     1981 acacaggact atatagcggc ggcagattac gttattacaa aggctggatg gggaactgtt
     2041 gcggagtgta ttctcgcaca gcgtccgatg gcactgttcg cccgcgatac agttttggaa
     2101 gatagaacaa ctatttgtaa attgcaaaaa ctgggtctgg caatttccgt cacaccggaa
     2161 aacctccacc gcgtagagcg ggtgattgag gacctcaaac agctagacac ctcaaatttt
     2221 gatacatttt atgatgctgc gagcgaaatc gcagacaaat tgatttctct catgcaatga
     2281 gagatgctct aaatttagaa aggagcaagc attattatga tggaaaaaga cgcaaaaatc
     2341 tacgtagccg gtcatcgtgg catggctggt tccgcaatcg tgcgcgagct gaaccgtcag
     2401 gactacaaca atattatcac ccgcacccat aaggagcttg acctgtgccg tcaggacgct
     2461 gttgaagcat ttttcgcaca ggaaaagccg gattatgtat ttctcgctgc tgcaaaggtt
     2521 ggcggtatta tcgcaaacca gaacgctctg gcagacttca tgtatgaaaa catgattctg
     2581 gaaatgaacg tcatcaactc cgcatgggag aatggctgta agaagttaca gttcctcggt
     2641 tcttcctgta tctatccgcg tatggcaccg cagccgatgc cggaaagctg tctgctgaca
     2701 agtgagctgg aaaagaccaa cgaggcttat gcactggcaa agatttctgg cctgaagtac
     2761 tgtgagtttc taaacaagca gtacggtact gactatatct ctgttatgcc tactaacctg
     2821 tatggaccta acgacaacta tcatcctact cacagtcatg tgctccccgc tttgattcgt
     2881 cgcttccatg aggctaagga agcaggtctg cctactgtta cctgctgggg tgatggttct
     2941 cctctgcgcg aattcctata tgttgacgat ctggcaaacc tgtgtgtgtt cctgatgaat
     3001 aactatagcg gtgacgagac tgttaatgca ggtactggca aggaactgtc tatcaaggaa
     3061 ctgaccgaga tggtagcaaa ggttattggt tacgaaggcg agattctgtg ggataccagc
     3121 aagccgaacg gtacacctcg taagctgctg gatgtttcca aggcaaccaa gctgggatgg
     3181 acatataaga ctgagttgga agatggcatc cgtctgtcct acgaggactt cctgaataac
     3241 ccgatgcgtg ctgaacgcta atttaccgag gttgctgtga tttttgagga ttgcagcagc
     3301 ctctttctta taaaaaggag agatcattat gaatattgtt ttactgtctg gcggttctgg
     3361 taagcgcctt tggccgctgt ctaatgacat ccgttccaag cagttcatta agattttcaa
     3421 aactgaagat ggatatgaat ccatggttca gcgtgtctac cgccagatta agaaggtaga
     3481 taacgacgca actgttacga ttgcaacctc taagacacag gtttctgcta tccataacca
     3541 acttggtgag gatgtgggtg tatctgtaga gccttgtcgc cgcgatacct tcccggcaat
     3601 cgcattggct accgcttatc tggtagatgt gatgggcatt gatccagaag agtccgtagt
     3661 tgtttgcccg gttgaccctt acgtagaaga tgactatttt gaggccctga aatctctgtc
     3721 cgatcaggct gacaaaggcg aagctaatct ggtgctcatg ggtattgaac cgacttatcc
     3781 ttccgagaag tacggctaca tcattcctga gagcgcagag cagactgctt tcgtaaatac
     3841 cttcaaggaa aaaccttctg aggctgtggc aaaggaatat atcgcacagg gtgcactgtg
     3901 gaacggtggt gtgtttgtct acaagctgaa gtatgtcatg gagcgtgcac atcagctgat
     3961 tgactttgta gattatcagg atctgttcaa caaatacgat actctgacta agatttcctt
     4021 cgactatgcc gttgttgagc atgaggacaa gattcaggta cagcgttttg ctggtatgtg
     4081 gaaggatctg gggacttgga atactctgac cgaaggtatg gaggaatcca ttatcggtaa
     4141 aggtgttatg aatgagaatt gcgatggcgt acacatcctg aacgaactgg atgttcctgt
     4201 gttggctatg ggtctgcatg atgtggtcat ctgtgcatct cgggaaggta ttctggtttc
     4261 cgataaggaa cagtccagct atattaagcc tttcgttgac aagttcgagc agcagatcat
     4321 gttcgcagag aagtcttggg gtagttataa ggttatggat gtagaagcag agagcatgac
     4381 cattaaggtt actctgaatg ctagtcactc catgaattat cacagccaca agaaccgtga
     4441 cgaggtgtgg gtggttctgg ccggtactgg taagaccatc gtggatggat atgagcaggt
     4501 tgttaaggct ggcgatgtga tcaccatgag tgctggctgt cggcatacca ttatggcaga
     4561 tactgagctg aagctgattg aagtacagct tggcaaggat atcaatgtta aagataaaca
     4621 gaaatttgag ttagagtatt aaaaaacgga ggagggctcg ttatacagaa accgttttta
     4681 ttgaagcctt ccgcaaagga ttatctgtgg gggggaaccg cctgaatgat gaatttgcaa
     4741 aaggaattga gatgtctcct cttgcggaaa cttggaatgc tctacgcacc cggatggacc
     4801 gagctttgtt gtgtctggtc agagtatcag gggatgacct tgacggaggt gttgcaagaa
     4861 cacccagagt ttctgggaac gcatccgcag accaaaggag aattgccgat cctgatcaaa
     4921 ttcattgatg cgaaaaagga tttgtctgtt caggtacatc ccacagatga atatgcaatt
     4981 gaaaaagaaa acgggcagct tggaaagaca gagatgtggt atgtactgga tgccagctta
     5041 atctatgggc tgcagaaaat aacagaagaa gctgtgatcc gtgaagcgat tgctcaggga
     5101 actgttgagc gttatcttca gaaggttccg gtcaaaaaga atgatgtgtt ctttattgag
     5161 gcgggaacga ttcatgcgat tggtgcgggt gcactaattg cagaaattca ggaaaattcc
     5221 aatctgactt atcgtctcta cgattatgac cgtgttgaca aaaatggtaa aaagagagaa
     5281 cttcatgtag acaaagcgct ggaagtagcg aacttgaaag ggttgtcaga accgaaacag
     5341 ccgcttcgtg ttctaaaata tcgtgctggt gtagctgcgg aattgctttg cagatgcaag
     5401 catttcgagg tctctcgtat gattgtcaac actgagagaa gacagacggt acactatcgt
     5461 gcggattcaa tcagcttccg tgtgttgctg tgtgtcaatg gctgtggtac cgttcgattt
     5521 gataatgaat cgttggacat ctataagggg gactgccttt ttgtgccggc cgattctact
     5581 gaaatcagca ttcacgggtc gattcagttt ctggatgtga gaggataata atatgaatta
     5641 taaagtagaa tatgagcgtt ggctgaatca tgccaatgca gatattatag aagaactgcg
     5701 ttcctattct gagaaggaca ttgaggactc tttctataaa aatttgtctt tcggtactgg
     5761 tggtctgcgt ggtaccatcg gtgcaggcac taatcgcatg aacgtacaca ccgtaggtaa
     5821 ggcaagccaa ggtctggcag actatctgaa taagaactat gaagccgctt ccgtggtggt
     5881 tggctatgat tcccgtatca aatctgatgt gtttgcaaag actgccgcag acatctttgc
     5941 tgcaaatggt attcaggtgc acttgtggcc agaactgctt cctgttccta cagtatcttt
     6001 tgcgactcgt tatctgaagg cagatgccgg tgttatgatt acggcatctc ataacccttc
     6061 taaatataac ggctacaagg tatacggtgc agacggctgt cagattacta ccgaggctgc
     6121 tactgcaatt ctggcagaaa tcgaaaagct ggacatcttt gctgatgtaa agatggatgg
     6181 cgatgcttct aagattgcat ccattcagtc ggaagttctg actgctttca tcgaagaagt
     6241 gaaggggcag tccgtcctgt ttggcgaaga agtggacaag aatgttgcta tcgtgtattc
     6301 tcctctgaat ggtaccggtc tggtgcctgt tacccgcacc ctggcagaga tgggatacag
     6361 caatgtgacc gttgtggaag aacagcgtct gccggacggt aatttcccaa cttgtcctta
     6421 tccgaaccct gaaattaagg aagctatgtc tctgggtatg gagtatgcca agaagtacaa
     6481 tgcggatctg ctgttggcca ctgaccctga ctgcgaccgt gttggtatcg cagttaagag
     6541 cgcacatggt gactatgttc tgttgtctgg taatgagact ggtctgctac ttctggacta
     6601 catctgttct cagagaatta agcatggaaa aatgcctgct gaccctgtga tggtcaagac
     6661 catcgtcacc atggatttgg gtgaacgtat cgcatccaac tatggtgttc gtaccatcga
     6721 tgtgctgacc ggctttaagt ttatcggtga gcagattggt atgttggaaa aggctggtaa
     6781 ggttgacagc tatatcttcg gctttgagga atcttacggc tatctgtccg gtagctatgt
     6841 ccgtgacaag gacggtgtta acgctgctta tctaatctgt gaaatgttct cttactacaa
     6901 gactcagggt atcagcctgc tggataagct gaacgagatt tatacaaagt atggctattg
     6961 tttgaacacc ctgcattcct tcgagtttga cggtgcggca ggttttacca agatgcagga
     7021 aattatggtt gaattccaca agggtctcga tataattggt ggtaagaagg ttattgaaac
     7081 tttagactac agtaagggcc tgaatggtct gccgaagtct gatgttttga agtttatgct
     7141 ggaagataac tgctctgttg tggttcgtcc ttctggtact gagccgaagc tgaagaccta
     7201 tatcagcgtc agcgcagaga acaaggaagc cgccgaagct atggaagcta ttatggctgc
     7261 tgaactggcg gaaatgttcg agtaagaaaa gaaaggagaa atcttgtaat ggaggaactg
     7321 ttttctaacg ctttgaaatc ggtgaagtca aatcgtgtgc tgtacacggc atcgttcttt
     7381 gcaagatcct ctcttttgta tttgcaggaa attggacagc tgactgctct gaaggcacat
     7441 acatctaggc gtacaggatt gtcatcttac ctttgtttcc tggtagaagt tggttcaggc
     7501 acattggagt ataaggggca gaaatatacg cttcaagtag gagatatggt gtttattgac
     7561 tgtttgaagc cgtatgtcca tgagtcatca gaagatgatt tgtggacttt gcggtggtgc
     7621 cattttaatg gcattggtat gacggaagtc tacaaaaaat accttgaacg aggtggtcaa
     7681 ccggtcttta aaacatcaaa aacagataag tatgctgact tgctgaggag ccttcatatg
     7741 gtggcagagg gacaggagta tgtccgggat atgaaaatca atgttctact cagtgaactg
     7801 ctgatgcatt tgatggaaga ttcttggaat cctgacaaag tgccgaattt ctctacaaaa
     7861 aaaatggaat tgcagaacat aaaacaatat ctggatgacc attacacgga gaagattacg
     7921 ctggatcagt tgagtgcaga gttttttatc aataaacagt acttagctaa gatttttcgt
     7981 gaaacttacg gtacaactgt tgtcggttat ctgaatcaga aacgaatcac acaggccaag
     8041 cacttgctac gctttacaaa tctaagtatg gaagagattg caacaaaaat tggcataaca
     8101 gatgcaaact atttttccag aacttttttc aaggtggaag gtgttcgtcc cagcgaattc
     8161 cgcaagatgt ggtaataaaa agccggcggt gttgagccgc cggtcagtac ctgtcgttaa
     8221 cccgcattca aagctttaat ctcagctttg atttcagcac gaacacgata gtaatcttca
     8281 gtttcgattt cggtatccag ccgagttgct gtcttttcgc agtcaggaca acgctctggc
     8341 tgttcgtcgg cagggaagct gtagtggcag gaatcacagg tgtaaatgtg atcgtcacgt
     8401 ataatcatca cctaccaatc cagtgcttag atttttcatg caattactat tatatcgaat
     8461 tggtgattcc acaaaaatcc gcttcttgat aaatgtacga ttcagagtga tatatagtac
     8521 tgtactgcca aagggaatac cacaacggca gaaatggatg attcacatgg aagaaattat
     8581 gcagatgatt ttagggaacg caaaattcca gctcggacag gtggtttcga cccctgctgt
     8641 attggaaact ttcaaccccc tgcagaccgc aaacggcatt cccgaagcct tgagcaacct
     8701 ttggtttaga caggaaatta gtattgcgga gatcgaggac gcagttctgg atgccaagaa
     8761 cggcaaggag ctagcaaaca gcctcaaccg catcaagctt ttccgcaagt tcaccctcga
     8821 ccgagagctg gacggcatgg tcagactgaa gggcacggac gtctggaaga acatcagcta
     8881 cctcaaggtc tacaccgcca cgccgcctaa gaaaccgacc cccccaaggt tccagtcgaa
     8941 cggctggagc cttttcttct ctcataaatc ggcataatgt atacaaatac agctccaaat
     9001 gattgtgtag tatatgcctg tggattgact tgatatagtc gagagactat ggcaatatac
     9061 acacaaccaa aggggaaaat cccaaaaaca aggaggaaac gctaatggca atgagcgaaa
     9121 aggcaaagaa atatttgaag gagatcaagg gtgcaaagac catcccggag ctgaaggatg
     9181 tggagatcgc aatcaagcga gacggtatcc ttgcttgggc agagttcacc aagttgaacg
     9241 aggcggtgga agagaagaag gtcgcccttc gcaagaaaaa gcaggagacc agccttcagg
     9301 agatcctttt ctgggcctac aaaaaggaat cagacaagct gctgaagatg atggacgagg
     9361 gagcagacaa ggatgccatc cagatgcagg tccagcgtta cgacagcatc ggccagatca
     9421 ttgcagaggc agacctcgaa gatgagtatg aggtttgaga atacagcctg aaccactaag
     9481 aaccaaatac cgaaagggac ttctgaaaca gacagaggtc cctttctttt gctcactttg
     9541 gcggtcaatt atgaaccaaa aaccagtcga atgattgtgg taagcgcccc atagaacagt
     9601 accttactaa caaatgcacc tcaagatata cttgagctat caagaagtct ggaggttttc
     9661 tatgtataaa ttaaatgaga ttgttcctgt ccaattagga aacgaaaaga gtgcaccaga
     9721 aaaaggtaaa cccgcggctg ccaagttagc gatgcgcatc aaaagagaga atggttctga
     9781 agttttgatc tataacg
//
LOCUS       DAXQKX010000081         9435 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.084, whole genome shotgun sequence.
ACCESSION   DAXQKX010000081 DAXQKX010000000
VERSION     DAXQKX010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9435
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.084"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..1379
                     /locus_tag="ACF3MF_002455"
     CDS             <1..1379
                     /locus_tag="ACF3MF_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HFE3928369.1"
                     /translation="GQFYVNKEVNLEKLSNLLHVCKTTLLNDINNIKKEFEEQIAYTH
                     REKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDEPDYLQLTECEFISVSKA
                     YSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRLGGFNSWELPESFFERAD
                     RFIESVTENSGRFYDKENKEILLIGFAISFLRQQVCAVTIDSKFIEEIKKRPIYNYVE
                     SAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDFQQLHQVFIDNTPEIKEL
                     VATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKFYLLNEEQTNLYKEVQTI
                     FSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYIVTNSDVHYLIYREALEA
                     VTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDAVQYENIIPISINTIDRA
                     IISAVQNK"
     gene            complement(1471..1836)
                     /locus_tag="ACF3MF_002456"
     CDS             complement(1471..1836)
                     /locus_tag="ACF3MF_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HFE3928370.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(1833..2198)
                     /locus_tag="ACF3MF_002457"
     CDS             complement(1833..2198)
                     /locus_tag="ACF3MF_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HFE3928371.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(2390..2638)
                     /locus_tag="ACF3MF_002458"
     CDS             complement(2390..2638)
                     /locus_tag="ACF3MF_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928372.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            2637..2765
                     /locus_tag="ACF3MF_002459"
     CDS             2637..2765
                     /locus_tag="ACF3MF_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HFE3928373.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            2822..4516
                     /locus_tag="ACF3MF_002460"
     CDS             2822..4516
                     /locus_tag="ACF3MF_002460"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050151 - oleate hydratase activity
                     [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HFE3928374.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKMTNTLTQ
                     EEEHVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            4616..4789
                     /locus_tag="ACF3MF_002461"
     CDS             4616..4789
                     /locus_tag="ACF3MF_002461"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928375.1"
                     /translation="MQAFEHRLPRGCEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQA
                     FEHRLPRGYEKVV"
     gene            5167..6300
                     /locus_tag="ACF3MF_002462"
     CDS             5167..6300
                     /locus_tag="ACF3MF_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HFE3928376.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQNGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYE
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            6331..6651
                     /locus_tag="ACF3MF_002463"
     CDS             6331..6651
                     /locus_tag="ACF3MF_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HFE3928377.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(6680..7144)
                     /locus_tag="ACF3MF_002464"
     CDS             complement(6680..7144)
                     /locus_tag="ACF3MF_002464"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFE3928378.1"
                     /translation="MVTYNWIKLREHPELVKQSAKWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(7273..8522)
                     /locus_tag="ACF3MF_002465"
                     /pseudo
     CDS             complement(7273..8522)
                     /locus_tag="ACF3MF_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            complement(8551..8868)
                     /locus_tag="ACF3MF_002466"
     CDS             complement(8551..8868)
                     /locus_tag="ACF3MF_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFE3928379.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(8894..9214)
                     /locus_tag="ACF3MF_002467"
     CDS             complement(8894..9214)
                     /locus_tag="ACF3MF_002467"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFE3928380.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDIINMADYGMMNGEKVLDQAEK
                     LINK"
BASE COUNT         3044 a         1860 c         1684 g         2847 t
ORIGIN      
        1 gtgggcaatt ctatgtaaat aaagaagtca atctagaaaa gctctccaat ctcctgcatg
       61 tttgcaaaac cactttgctc aatgatatca ataacataaa aaaagaattt gaagaacaga
      121 tcgcttatac acatcgggaa aaggaccgtt acactttata tttttcagaa catatacctc
      181 gatgcaagat catgcagcaa ttgtctcaaa attcgttgtt tttaaaaact tgtctgcttt
      241 atttggaaga agatgaacct gattatcttc aattaactga atgtgaattc atctctgtca
      301 gcaaagctta ttcattaaaa aaacaagtat tagcttattt taatgactgc gggatcgaaa
      361 tcgaccgcta ctcccctcga ttcactgaaa tggaaagacg tctgctgctt cttaatgtgt
      421 cgtatcgttt aggcggtttt aattcttggg agctacctga atcgtttttt gaacgtgccg
      481 atcgtttcat tgaatccgta acggaaaata gtggcagatt ttatgataaa gaaaataaag
      541 aaatcttatt gattggtttt gctatcagtt tcctacgcca gcaagtgtgt gctgtgacaa
      601 tagattcaaa atttatcgaa gaaatcaaaa aacgtcctat ttacaattat gtcgaatcag
      661 catgggaaaa cactgatttc caaacctatt ataaaaaaga agaattcgcc tttattttga
      721 cactattcaa tctttgtaat tatggtttcc attcttatca gttgattgcg gaagactttc
      781 aacagctaca ccaagtgttt attgacaata ctcccgaaat aaaagaacta gttgctacct
      841 ttgaatctca cttcaatcaa gaattattcg gaaaccaacc attcgaacgt gcgctgattc
      901 atctgatgcg ttcggcttgg gataactatc aattattcat gccagaaaaa ttttatcttc
      961 taaatgagga acagacaaat ttatataaag aagtccagac aattttttcc agctggtcca
     1021 gccagttacc ttatgatcta cggttgaatc ctaattgcat gcgggctttt gtgatcgaat
     1081 tgagcggaat tctccgtctg acaaaagaac atctgactat ctatatcgtc acaaattcgg
     1141 atgttcatta tctgatttat cgggaagcct tggaagctgt aactactttc gattttcaag
     1201 ttgcaccaac aatttattca agtatatctg atataaagaa gtatgcgcag cagtcctcaa
     1261 accgggtatt atgtgaacgt acattatata caccagatgc ggtccaatat gaaaatatta
     1321 ttcctatttc gatcaatacg atcgatcgag ctatcatttc agctgtgcaa aacaaataag
     1381 ggactgtgac aaaaatcatg tcacagcctc ttatttgttg aagatgccca tttctgtaac
     1441 aatctcttga tacacatcag gctcacaacc tcacttattt tggacatcta cgggtccgat
     1501 ctctttattt aaaaaataag aaatgatggt tcggataact accaacgccg ctagttggaa
     1561 aatatcctgc aaggtaggtt tgataatcga ttcgatgatc ccagctgaaa caagaatttc
     1621 caaacttaga agtatatagc ctcccaacat ctttttaata gcattgttct cgctgactcg
     1681 gtcgctttgc acttttgtat ggacaaataa atatttcaaa aaatccttga ttgatagaca
     1741 aacaccccaa accaataaac agatagcaaa gatatcaagt cccagtacaa gtttttcaaa
     1801 atatggaaga agaaactgca tcaactctgt cgtcatccta cctctcctct tctttgtttt
     1861 tctttgtctt ctatttcctg attcaagaaa taagaaatga ctgttcgaat gataataata
     1921 agtgcaagct tcaaaatatc tgtccaagtc ggcttgataa ctgactcgat gatatcagca
     1981 acgactagta cttccaagct taacaaaata taacttgcta gcagttttct tgtatctgca
     2041 ttacgagtat tacgttctgc atagtttttc ttgacatgag accaatcaaa aagtttgaat
     2101 agaacaagaa cgatcccgac aattaagata ccgatagaac aaatatttaa aatagcaatg
     2161 atccattcta gaaattcaat taaatttgag cgaaacatat acgctaccta ctttctttta
     2221 atttgttcct attcttttat tgtaaaagaa agttaccttg ttcgtctatt taaaagttgt
     2281 tctaatgata acggttcgct taaatttttc tttttcactc tccccttttt ctccctccat
     2341 ccataaatcg tggaagtatc caaaacaacg tagcaagtta aaataaggct tagtccgtca
     2401 tcagcttttc aaagaagcac tgtctcggtg ctttttttgt acccaaattt ctaaaaatag
     2461 aaccatacac ctcctcaaat cttttcttct tacctaccct atttttattt acaggaaaat
     2521 cagacacttc ttcttttttg tcaaaatttc ctttttcttc tcgtcctatc atttggcatt
     2581 ctaataaaaa cgaactatcc ttggatatag aaagagaaaa caaggaggcg tttttcatga
     2641 gtaaaaaatt aatcaaagtc ggcatcggtt taggtttgct tgcccttggc gctgcatatc
     2701 taggaaaaaa gacaggacta ttcgaagatg acagtcattt atatgatgaa ttcgaatcaa
     2761 tctagcatcc tatttagttg aatcactacg gacatacttg gaagacattg gaggaatcac
     2821 aatgagaaaa agtaaagcaa taatgattgg tgccggtatt gccaatatgg cagcggctgt
     2881 ttatttgatt caagaaggca aatggaaagg ggatcagatc accttttatt cattggatga
     2941 tcacggttca aatgatggtg caccgaccga cactgtagtg gatgaatatt ggaataaaaa
     3001 ccatccatta gaaaaccaaa aaggctatat tgctcgaggc ggtcgcatgc ttaattaccg
     3061 tacctatgta gatttgatgg atctgttaag tcgaatacct tctgttactg agccagggat
     3121 gactgctgaa gaagatacga gagattttga tgcaaaacac cgaacctttg acaaagcacg
     3181 tttgatggaa ggtggcaaag gaatcattga tggcggaaaa ctgggattca ataataaaga
     3241 ccgtattctt ctgactaaac tgattgctat gcctgattca gaagaagaaa aactagacaa
     3301 tatcactatc gaagaatatt tcaaagatga tccacacttt tttgaaacaa acttctggtt
     3361 tatgtgggaa acaacatttg ctttcagaac acgtagttct gctcaagaat tgcgtcgcta
     3421 tatgcatcaa atgatttatg aattcactca aatcgaacat ctagtgggcg tcaatcgaac
     3481 acgttacaat caatacgaaa gtattatgct tcctttgatc gagtacttga aagaacaagg
     3541 atgcaaaatc attttgaacc gccgtgtcac tgactgggaa ttcaaagaaa caccgatgca
     3601 agatgaaatc actgtgactg gtttgaaaat gaccaataca ctgactcaag aagaagaaca
     3661 cgttgtggtc gatgaagata cagcagttat tttcactaat gggtccatta cagattcagc
     3721 tactttagga gattacgaaa caccagctgt agaaaatatg gattatggtg cagcttctag
     3781 tctctggaaa aaagccagtg aacgtttcta caacttggga aatcctgaca aattctttgc
     3841 tgatcgagat gcaagcgaat gggtcagctt taccctgacg acgaaaaacc atttgttgtt
     3901 gaatgaaatc acccgtatca cgactcaaga accaggaaat gccttgaatt catttatttc
     3961 aaccacaccg atcacgccgt taggccaaaa agatgtcaat atgtctatcg tcgtgcatca
     4021 tcaaccgcat tttacgtctc agaaaccaaa tgaaacagtt atttggggtt atttccttta
     4081 tccaagacga cgtggcgaat ttgtggataa acagtatatt aaaatgaatg gaaaagaaat
     4141 gctagaagaa ctgattggac aactttcaaa agtagatcct ggaccagtga atattcgtga
     4201 aaaagaaaca gaaattttcg acagcgtaat aaataatatc cctgtctata tgccttatgc
     4261 ttccgcgttg ttcaataatc gtgccaaaag cgatcgacca aaagtcattc ctaaacattc
     4321 gaccaatctg gcctttacag gagaatttgt cgagcagcct tatcagatga tctttactga
     4381 acaaagtgct gtacgttctg gagaaatcgc tgctttccat tttgcgggta tccctatgtc
     4441 acgtcttgtc aaaacaccgc gttacgacaa agatattcct actctagctc gtgccgcaaa
     4501 aaaaatgttt gaataatcaa gaggttgtga aaaagctgcc ctgcatcaag taataagaac
     4561 aaccaggcta aaacagcttc ttatgttttt gatttggttg gacttattac cgcagatgca
     4621 agcttttgaa caccgtttac caagaggttg tgaaaaagct gccctgcatc aagtaataag
     4681 agcagccaag ctaaaacagc ttcttatgtt tttgacttgg ttggacttat taccgcagat
     4741 gcaagctttt gaacaccgtt taccaagagg ttatgaaaaa gtcgtttagt ttcgagtatg
     4801 aagaaaaatt ttgtgaaaat ggttcctcac gtttttgcat aaatttgact taataccgag
     4861 aaactgatcc cttctgtcat aacctctttt tatttatgtc tgtttctttt tgaaaacaac
     4921 cattttttca acgtttactc tcttgccaat ccaacatcat ctaacagata caactatttc
     4981 aatgattacc attacactaa aaaatcggaa actcacctct ccgaacacaa atacataaga
     5041 ctatagaatg tttcatttaa gaaaaaaagc gtttcattat caaaaaggta agatctcctt
     5101 taaaatgaaa ttatctgtag tactaataat gcagacaatt ttatgaatct gaaaggagca
     5161 tctccaatga aagcagtcac ttggcaagga aaacagaaaa tggaaatcag aaacgtagat
     5221 gatccaaaaa tattagaacc aacagatgca atcatccgta tcacagcaac agccatttgc
     5281 ggctccgatc tgcatcttta ccatcatggt gaagcagttt tggaaaaagg gtatgttgta
     5341 ggacacgaac caatgggaat cgttgaagaa gtgggatctc aagttcaaac attgaaaaaa
     5401 gggcaacgtg tggttatccc ttttaatatt agttgtggtc attgtcattt ctgcctgaat
     5461 cacatggaaa gccaatgtga tgaatcaaat ccagatcagt tatatggcgg gcttttcgga
     5521 tttggcaagt tgaacggtaa tcattggggt ggtcaagcgg aatatctaag agttccttat
     5581 gcagactcta cttcatttgt tgtaccagat aatgatcttc ctgatgaaaa agttttattt
     5641 ctatcagata ttttgcccac agcttattgg agcgttgaaa acgcaggagt aaaaaaaggc
     5701 gatacagttg tgattctagg ttctggtcca gtcggtctat tcgctcaaaa attcgctgtt
     5761 atggctggag cagagcgcgt aatcgcagta gatccagtac agcaccgtct agataaagcg
     5821 gctaattaca atggggttga aacttatttc ttagaagaca cggcacaagc tggaacagaa
     5881 ttgtatgaac tggctaaagg tggcgcagat gtcattatcg attgtgtagg aatggacgga
     5941 ttagagcctg tcaaagaaaa agcgaaaaat ttagtaagct tacaaaacgg cacaatctct
     6001 ccattacaga tggcatcgca agctgtcaaa aaatttggaa cagtccaagt aactggtgtt
     6061 tatatgactc cagcttcttc ttacccgctg caagaatttt ttatgcggga tatcgctgtc
     6121 aagcatggac aggcaccaat tatccatcta atgccaaaaa tttacgaaat gattgcagaa
     6181 ggactattcg atcctacaca aatcattact cattcgctgc cactatcaga agcagcacaa
     6241 gcatatgaga tctttgacaa aaaagaagat aaaaatataa aagttgtttt gaaaccttga
     6301 attcagtaaa aaatacaggt gattttcttt atgcccaaaa tcaaacgaaa tacccatgag
     6361 atcgaaatag gaaaagaaga agatatcgaa atacgaggac gtcgcttccg cttctatttc
     6421 caaaatcgtt acacattgat ctcactggct gtcgatttat taaccgggat tttctatatt
     6481 tttggaagcc ttgcttcctt aactaaaatc cccgatcgat atggcaccta tttttatttg
     6541 gctggtgcta ttttcttgac gattcgtcct attctcagaa tcgtaaggaa catttttatt
     6601 tacgacgaaa aaaaagcaat gaagagaaca agcaaaaaaa aagaggcatg agatttgaaa
     6661 aaatctcatg cctctttttt caccctatcg tatcactttg atacagacga gcggtcgtcc
     6721 cactttcttc cttgaccatt gtcaaaaatg tccactcgta tcgttcataa aacgtggtat
     6781 gatctgtaat taagtaaagt ttttcgtacc caagttgatg catttctttt ctgatttccg
     6841 ctaatatccg cttggctatc ccctgcttac gcttttccgg ttcaacaaac agggcacaaa
     6901 gatttggtgt caaatcaggg cggttatgga agtcgttttc aataacgccc gctcctccga
     6961 cgatggtttc tttttcatct aagaccacat accattgagg aatactttcc ttattagcga
     7021 ttccagtacg aatactttcc tcatacacaa cagcaggaac tccccatttt gatgaaaacc
     7081 acttcgcact ttgttttact aattctgggt gttctcttaa tttgatccag ttatatgtaa
     7141 ccaatgttta aacctccgac taaaataaaa cgtttacaaa aattatacaa gtctttatga
     7201 aaattagcaa tgacaacaat agtgatgtaa aaaaaacgga aaacaatcac ttgttctccg
     7261 ttttttgatt aatcaagcat ctaaagcttc ttttcttctt tcttggatcg tagctacctt
     7321 gacgaacggt agatagatca aaatagaaag aaccaaattg acagcggcta gtacaccacc
     7381 tgcaatactt tttgttgcca atacaccgcc aataattggt ggagttaccc atggaggcat
     7441 aacggtagct gctggcacta aacctgtaga agtcgcaaag taagcaacac taactaagac
     7501 cattggtgtc aaaataaatg gaatgaacat gatcgggttc aacacgatag gtaacccaaa
     7561 catcgttggt tcattaatat tgaagacacc tggcgcaatc gacaagtttg ttacaaccat
     7621 atatggtttg tttttacgtc ctactaaata aatagctaac agtaaaccta aagttgcacc
     7681 tgttcctcct aagttgacaa agctgtcaaa gaaaggtttg ttcacgataa acggtgcgct
     7741 atgtccagct gcgattgcat taacgtttgc ttcaatggct ggcgcattga ttgtttgcat
     7801 caaaggatcg accatattcg ctccgtgtaa accaaagaac cataagaatg gtgtgataaa
     7861 tgcaagcagt aaggcagatg gataagagtt tgcaagtccc ataaatggtt cttggaccac
     7921 tgtatagaaa gaacctacga tatcatcaac accgaatgca gcaaaaattg cagcaactaa
     7981 agcaaacgca gagatagtga tcattgctgg tagtaatgaa gcaaatgctt ttgcaactgc
     8041 cggtggcaca ccatcaggca ttttgatgat caatttttca tttccgctta aacgtacaaa
     8101 gatttctgtt gaaataatcc caacaataat agcaataaac aaaccgtttg agctcatacc
     8161 taatgctccg cctaaagcga agaaagagcc taaagaaatc acacctgcgg aaacaccgtc
     8221 ttttcggtag ccgttagcta aatgataagc aagaaagcaa tcaagacaga aagaatggca
     8281 aatgtaccgt tccaagcagc agccccgaat cctttccatg attcaccacc aaaaattgag
     8341 ttcatcaatt cttggaaccc gggaatcggt aagttattga tcattactgc taatgctcct
     8401 aagatcatta acggcatact caccataaat gagtcccgaa tcgcaactaa atgccgttgt
     8461 gcaccaattt ttgatgctac aggtataaaa tgtttctcca taaatgcaac aaatttatcc
     8521 ataaatcttc cctcttttct ttactgtaga ttacgcgttc aatcgacgat acagatcaat
     8581 gatctctttt gctaaatctg taaaagctat ggatgtcatc agatgatctt gactgtggac
     8641 tgtcaaaagc gtgacttcaa cgtgatttcc ttgtgcttct tgtgtcagca tctctgtttg
     8701 agagtgatgt gcttggacta aagattcctc tgcatctttg attttttcat ctgctaaagt
     8761 gaaatcacct tttttcgcag cagcaatcgc ttccattgca tcgctttttg catttccgcc
     8821 aaacatgatc agacccatga tggcttctag atttttttga tcttccattt attgtatcct
     8881 ccgataattt ttattatttg tttattagtt tttctgcttg gtcgagtact ttttcaccat
     8941 tcatcatgcc atagtcagcc atattgatta tatctaaagg aatgccttta ggtgctagct
     9001 tttcagcaaa ttgattttgc ataaagcgta cttgcggtcc taaaagtaaa acgtctacat
     9061 ttttagattc tagttgatta tccgcatctg aagcagatac agcaaagatg tctgcttcca
     9121 ttccttttgc ttctgctgcc ttttgcattt ttgtgactag gagacttgta ctcattccag
     9181 ctgaacatac aagcatgatt gttttctttt ccattttaaa cacgttcctt tctatactta
     9241 cacttgtata taagcaagta gcgtgccaac tttgaaagcg ctttaaaaag ttgatatcat
     9301 cacatttaag gtctatacca agttgcatac acactaaaaa agaaagtgca cactaaacac
     9361 acaaattaat ttttattacc ttttttcttt taacgtgcac aaaaaaagtt gtgacacaaa
     9421 acttgtcaca acttt
//
LOCUS       DAXQKX010000082         9349 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.085, whole genome shotgun sequence.
ACCESSION   DAXQKX010000082 DAXQKX010000000
VERSION     DAXQKX010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9349
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.085"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(59..1003)
                     /locus_tag="ACF3MF_002468"
     CDS             complement(59..1003)
                     /locus_tag="ACF3MF_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HFE3928381.1"
                     /translation="MDTILITGGAGFIGSTLANYLGKENKIVVVDDLSMGKKENLDMD
                     KQVTFIEGDVSDSQLMERIMKEYQFAYIFHLAAVASVADSVERPVETHRVNFDSALLL
                     LELARKYQSNLKRLVFSSSAAVYGDEPTLPKKEESVIRPLTPYAIDKFAAEQYVLDYC
                     HLYDVPTSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQLAGEKAEFTLFGDGSQSR
                     DFVYIEDVIQALLLVAKEEKALGQQFNVGTGKSTTLLELIHSIDQILGTELALKYEAE
                     RSGDIRDSLADISKIRSLGYQPKFDILSGMERYLKTEI"
     gene            complement(1137..2528)
                     /locus_tag="ACF3MF_002469"
     CDS             complement(1137..2528)
                     /locus_tag="ACF3MF_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HFE3928382.1"
                     /translation="MLNERFLKYVKGWYFIYFGFILMLRAIGPYLLLPTRYDTLLFWP
                     AGIAGVVLIIIDAIIAFREKNLKKYDWLLIAFIGAMLVSSLMNLKYGYSENIKLIMWQ
                     LIFFFMIYQFGKDYSSNFFFKVFTWILSLVWFLANLVSLYWFVIQYGIKIPIKYKYYP
                     VRLGWLGNRLFGVYTDPNFGAVISLIVIIIAIYYLVTYKHLNLLFKIFFVINIFIQFS
                     FIALSGSRTTLVCLLITTFVFSFFTSYSSRFLKTNTLKRWLTALVVGLLSIIAMYYVT
                     DITAHAWAHVPHITEVKKDTSDSSGTTSSNKVDLKRPDTDSGDVSNLRFELWKSAIEI
                     FKSKPISGGSPGYYIEYAHDKLPYTLMGKDTLTAHNFIFLVMAATGGLGLLTLLTFLF
                     IQCFKALRYCFTQPNLVKDKHFFAILMILTIAVSALFITELILVSTIGSFIFWGYLGS
                     IQKTISKEEGVTN"
     gene            2654..3064
                     /gene="tagD"
                     /locus_tag="ACF3MF_002470"
     CDS             2654..3064
                     /gene="tagD"
                     /locus_tag="ACF3MF_002470"
                     /EC_number="2.7.7.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0047348 - glycerol-3-phosphate
                     cytidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate cytidylyltransferase"
                     /protein_id="HFE3928383.1"
                     /translation="MKRVITYGTFDLLHYGHINLLKRAKQYGDYLIVALSTDEFNWNA
                     KQKKCYFSYEKRKQLLEAIRYVDLVIPEENWEQKVKDIKEYHADYFVMGDDWAGHFDE
                     LEQLTDAQVIYLPRTPEISTTQIKNELNSLNSDK"
     gene            3438..3653
                     /locus_tag="ACF3MF_002471"
     CDS             3438..3653
                     /locus_tag="ACF3MF_002471"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928384.1"
                     /translation="MIILNRSGNKQTYLRLRKQHYHCQSCGKYFTAHTYLVAPSCFIS
                     KQVHYTILEELTERQALKTIAKRCDFQ"
     gene            3810..4067
                     /locus_tag="ACF3MF_002472"
     CDS             3810..4067
                     /locus_tag="ACF3MF_002472"
                     /inference="COORDINATES: protein motif:HMM:NF013753.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFE3928385.1"
                     /translation="MTFCPAGEKKDLIAYFMRFTRKAHMGVRYIVTDMNAPYFSLVKE
                     PFPNAQIIIDCFHIGQHLNKFFDRVRKRVMKQLNQKCQRHL"
     gene            4154..5392
                     /gene="istA"
                     /locus_tag="ACF3MF_002473"
     CDS             4154..5392
                     /gene="istA"
                     /locus_tag="ACF3MF_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HFE3928386.1"
                     /translation="MRKDIREGVMIYVINEIKPNYAALAKQYDCDYRTVKHAYEEAQV
                     KESKPPERKKRPSKLDPYREIIQDKIKDQCSAYSIFKFIEHKGFGGSYSLVKTYCRQI
                     KQAKVHKATVRVEHSPGLSAQVDWKEDMRLISNQGEIFEFNIFLYVLPYSKKKYVTLT
                     FDRKQDTLFECLDDAFYQTGGVPKEIWFDNMKTVVDHSRSQFSKPHFNKRFYAFSKDA
                     GFTPIACRPFRPQTKGCVEALARTVDRLRVYNHEFYDAVELCHLVNNLCVELNNEVSQ
                     STDQTPDERWQTNEKEHLHPYQKNLLNPYFEDFIRRKVTKEEMVIFRKCRYSVAPRYI
                     GKEVEIELSDKEDQVQIYYNGELIRSHPLTTKQLNYHEEDYFQILKSDVMSHKEDDGI
                     RAYTRESLKQYDLVEVADEE"
     gene            5382..6122
                     /gene="istB"
                     /locus_tag="ACF3MF_002474"
     CDS             5382..6122
                     /gene="istB"
                     /locus_tag="ACF3MF_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HFE3928387.1"
                     /translation="MKNSHYQELMTNLETLGLNHMREYVPNYIEVANREELSLTEALL
                     ELTRREVDHQNKQKMNRVVARARFSKRTSLEEFDFAFQPSINKREVLDLRHMGFVEKH
                     ENLVFIGSPGVGKTHLTIALGIEACRQGYRTLFITCHELLLRLRTAYEKGTLERVLKR
                     YARYDVLIIDEIGYLPIQKQEADLFFQLLAMRYEHRSTIITTNIVLSRWGELFQSSEI
                     AAAILDRLVHHVKVFKITGKSYRMRDKI"
     gene            6541..6696
                     /locus_tag="ACF3MF_002475"
                     /pseudo
     CDS             6541..6696
                     /locus_tag="ACF3MF_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6763..8190)
                     /locus_tag="ACF3MF_002476"
     CDS             complement(6763..8190)
                     /locus_tag="ACF3MF_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFE3928388.1"
                     /translation="MKKTVKDIFYNAIYQVFLIVLPLLTIPILSRRIGSTGLGIYGYV
                     FSISQFLMTVIAVGMNPFRIRNIAKSRKDKKALSLQFWNIYFLQFLIGLSVSFLYIAY
                     IYFFDVKYKNLYLIQLIFIAGLTLDISWFFQGIEEFSKVVIRNTVIKLSSVLLIILFV
                     STKDDLWIYVFITSITNFLGSLVFWLSIHGKVGKPLFNSNVFKQLWKPAFIILTPQLF
                     MQVYTTLDKTIVGYFVDPTALSYYDQSQKIARIILAVLTSITIVMLPKISKAQAEGKS
                     ENILVYTKKSFDYTIIIALILFSVVFINTKEFVPWFFGENFKPMTINMLISCLIIVVS
                     PIGGVFANQFAIAIEKDKEYAYPMIIGAIVSIIGNVAFVPTYGAVAATIVLVVVELLV
                     FFFRVFFVRKEIKISYFFGKNVVLFFIVNLTLTTSAYYFLPQLFSSSFLDMAIKSIMI
                     FIIYLPFVYFLFPDIRNEVRKIIRK"
     gene            complement(8187..9329)
                     /locus_tag="ACF3MF_002477"
     CDS             complement(8187..9329)
                     /locus_tag="ACF3MF_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HFE3928389.1"
                     /translation="MKNIKKFFSRNIFPVFIKILPIQKNLIVFSSFGGRNYSGNPRVI
                     SEKIHEKKLNYRIIWLIKKEAIITDLPDYIKRIDSDSFLAAFYLYTAKYWIDDSRKTI
                     KYAKRKKQFYFQTWHGTPLKKIEFDAKDKLPKRYLSYAKKDSESITYLLSGNRYSSEK
                     YVSAFNIVPSKILEVGTPRNDELASSKEQVFDLKKKQINVLFAPTFRNNIEDNGITQL
                     EWLGVDNLREFFKKQQQELNLMTKFHPNVHSKLATDSKSIEYMKKHQITLINDGIPLE
                     MLFEEIDVLITDYSSIFFDFALTKKPIILFNYDEKEYSLERGFYIQLSELPIISVQDS
                     YGLVDVFKNQQEKLLKSSQELLDYIGNYETGASTEKVLELLERDIK"
BASE COUNT         3250 a         1692 c         1461 g         2946 t
ORIGIN      
        1 ctttaattct tgttttactt tttagaatta tttatccaaa gatgcaatca ttttttcatc
       61 aaatttctgt ctttaaatac cgttccattc cgctcaatat atcaaattta ggctgatagc
      121 ctaaagaacg aatttttgaa atatccgcta aggaatcacg aatatcccct gaacgctccg
      181 cttcatattt aagcgctagc tctgttccta agatttgatc aattgaatgg atcaattcaa
      241 gtagcgtagt gctttttcct gtaccgacat tgaattgctg tcctaaagct ttttcttcct
      301 tggcaacaag taaaagtgct tgtataacat cttctatata aacaaagtct ctagactgac
      361 tcccatcgcc aaataaagta aattccgctt tttctcctgc caattgtttt ttgtaacgat
      421 ccactagaat cgaaatgact ccgctatatg gagagtttgg attttgattt ggaccataaa
      481 cgttaaaaaa tcggacagca ctagtcggaa catcatataa atgacagtaa tccaaaacat
      541 attgttctgc tgcaaattta tcgatagcat atggtgttaa tggacggatg actgattctt
      601 ctttttttgg cagtgttggt tcatcaccat aaactgcagc tgatgaacta aatactaatc
      661 gttttaaatt agattgatat ttccgtgcta actcaagcaa taaaagcgca ctgtcaaaat
      721 ttacacgatg tgtttctaca ggccgttcta cagaatctgc cacactagct acagcagcta
      781 gatgaaaaat ataggcaaac tgatattctt tcatgattct ttccatcaat tgagaatctg
      841 atacatcccc ctcaatgaaa gtcacttgtt tatccatatc caagttttct ttttttccca
      901 ttgataaatc gtcaactact acgattttgt tttcttttcc caaataattc gctagcgttg
      961 aaccgataaa accagctccg ccagtaatca atatagtgtc catcaaattc actccaattg
     1021 cacattttcg tatcaaataa tattagttta ccatttttat attgtaaaaa ctataaaatt
     1081 tgttgaagtt gggataacta gttttctttt ctactttcat atacctaaaa atagtttcaa
     1141 ttagttactc cttcttcttt agatatagtt ttttggatag aacccagata tccccaaaaa
     1201 ataaatgaac ctatcgtact aaccaaaatg agttctgtga taaataatgc cgaaactgct
     1261 attgtaagaa tcattaaaat agcaaaaaag tgcttatctt ttactagatt tggttgtgtg
     1321 aaacaataac gcaaggcttt aaagcattgg ataaataaga aggttaacaa tgtcaataga
     1381 cctaatcctc ctgtagcagc catcactaag aaaataaaat tatgagcagt taaagtatct
     1441 tttcccatta atgtatatgg tagtttatca tgtgcatatt caatatagta gcctggagaa
     1501 cctccggata tcggcttact cttgaatatt tcaattgcac ttttccaaag ttcaaacctt
     1561 aaattagaaa catccccgct atcagtgtca gggcgtttta aatcaacttt attgctgcta
     1621 gttgttcctg atgaatcaga tgtatctttt tttacttctg taatatgcgg aacatgtgcc
     1681 catgcatgag cagttatatc tgttacataa tacatcgcaa ttatacttag caatcctact
     1741 actaatgcag ttagccatct ttttaaagta ttagttttaa gaaaacgact actataactt
     1801 gtaaagaaac taaaaacaaa agttgttatt aataaacaaa ctaatgtggt gcgtgaaccc
     1861 gataaagcaa taaacgagaa ttgaataaaa atattaatta caaaaaatat tttaaataga
     1921 agatttaaat gcttgtaagt gaccaaataa tatatagcaa taatgatgac gattaatgat
     1981 ataaccgcac caaaatttgg atctgtatat acaccaaata aacggttgcc taaccaccct
     2041 aaacgaactg ggtaatactt atattttatt ggaattttta tgccatattg aatgacaaac
     2101 cagtataatg atactaaatt agctaaaaac cataccaatg aaagtatcca ggtaaatact
     2161 ttgaaaaaaa agttactact atagtctttg ccaaactgat aaatcataaa gaaaaagatt
     2221 aattgccaca tgattaactt aatattttcg ctatatccat attttaaatt cattaaactg
     2281 cttactagca tcgcgccaat aaaagcaatt aatagccaat catatttttt tagatttttt
     2341 tctctaaatg caataattgc atctataatg atcaagacaa ctcccgctat tccagcaggc
     2401 caaaaaagta aagtatcata tctagtaggt aatagtaaat acgggcctat tgctcgtaac
     2461 attaaaataa aaccaaaata aataaaatac caacctttca catattttaa aaatctttca
     2521 ttcaacattt ttcctccatc cacctatttc tcataaatat ttcttatcct ttttaggata
     2581 aactggtcct ttcaattcta acaaaaaaat gctaaactaa caatgtatat taatgaattt
     2641 cgagaggtga aagatgaaaa gagtaattac ttacggtacc tttgatttgc ttcattacgg
     2701 gcatatcaat ttactgaaac gagcaaaaca atacggagac tatcttattg ttgccctttc
     2761 tacagatgaa ttcaattgga atgcgaaaca aaaaaaatgt tattttagtt atgaaaaaag
     2821 aaaacagtta cttgaagcta ttcgctacgt tgatttagtt attcctgaag aaaattggga
     2881 acaaaaagta aaagatataa aagaatacca tgcagattat ttcgtgatgg gcgatgattg
     2941 ggctggacat tttgatgaac ttgaacaact aacagatgca caagtgattt atttaccaag
     3001 aacacctgag atctctacaa ctcaaataaa gaacgaactt aattctttaa atagtgataa
     3061 ataatatttt ttaaacaata aaagaacaat atatctggat aagacgtaaa aaaatggctc
     3121 tataatttct aggactgata gaattttctg tcggtcctag attttttgta aaaaaaaaca
     3181 gacataaaaa aattccgata gaatagagtc gtctaaaaca tcaatctgaa aggaagtttt
     3241 tgatatccat ttctcattct atcaaagagc tcttcactat taaagataaa aatattgaaa
     3301 ttaattcttt tcaagaaact ttttataagg acaagaaagc catcgtaatc gaaggtccat
     3361 tagttcgcac ttttagacat tgtctatttt gtaaagaatc tgcaaagcag atcgagaaaa
     3421 acggcaagaa gatttcaatg attatcttaa atcgcagtgg gaataaacaa acctatttgc
     3481 gtcttagaaa acaacattac cactgccaat catgcgggaa atattttact gctcatacgt
     3541 atcttgtcgc tccttcatgt tttatttcga aacaagttca ttacacgata ttagaagagt
     3601 tgaccgagcg tcaagcatta aagacaattg cgaaacgttg tgattttcag taacgacagt
     3661 tcaacggaca ttatctgctc tatcggcaac gctgcgacag aagctagact atttacctca
     3721 ttgtttacta ttcgacgagt ttcgctctct ttcaattttc catgggaagt tctccttttc
     3781 ttgtatgaat tgagagacag ggaagctctt tgacattttg tccagccgga gaaaaaaaag
     3841 atttgattgc ttatttcatg cgttttacaa gaaaagctca tatgggggtt cgatacattg
     3901 tcacagatat gaatgcccct tatttttcat tagtcaaaga acccttccca aatgcacaaa
     3961 tcatcattga ttgctttcac attgggcaac acttgaacaa gtttttcgat cgtgttcgaa
     4021 aacgtgtgat gaagcagttg aatcaaaaat gtcaacggca cctttaaaat gtaggaaaac
     4081 ggcaatttaa aattgttggt ttacctacat ttttgtatgc tcttcttatc ccaaatgaaa
     4141 tggaggctca gggatgagaa aagacatacg cgaaggagtg atgatctacg tgatcaatga
     4201 aatcaaaccc aattatgctg cactagcaaa acaatacgac tgcgactacc gaacagttaa
     4261 gcatgcttac gaagaagccc aagttaaaga atcaaaacct ccagaacgta agaagcgtcc
     4321 aagtaagtta gatccctaca gagaaatcat ccaagacaaa atcaaagacc aatgcagtgc
     4381 ttacagcatt ttcaagttta ttgagcacaa aggatttgga ggaagctaca gtttagtaaa
     4441 gacctattgt cgccagatta agcaggcgaa agtacacaag gcaaccgtcc gagtcgaaca
     4501 tagccctggg ctttctgctc aggttgactg gaaggaagat atgcgactaa tcagtaatca
     4561 gggcgaaatt tttgagttca atatcttttt gtacgtcttg ccatattcca agaaaaaata
     4621 tgtcacacta actttcgacc gaaaacaaga cacactcttt gagtgcttag atgatgcgtt
     4681 ttatcaaacc ggtggcgttc ccaaagaaat ctggttcgat aatatgaaga cagtcgttga
     4741 ccattctcgt agtcagtttt ccaaaccgca tttcaacaaa cgtttttatg ctttcagtaa
     4801 ggatgccggc ttcacaccaa ttgcctgtcg gccatttcgt ccgcaaacaa agggctgtgt
     4861 cgaagcttta gccagaactg ttgaccgcct acgggtctat aatcatgaat tttatgatgc
     4921 cgttgagctg tgtcatttag tgaataacct ttgtgttgag ttaaataacg aggtttctca
     4981 atcaactgat caaacaccag atgaacgttg gcagacgaac gaaaaagagc acctgcatcc
     5041 ataccaaaaa aaccttttga atccctattt tgaagacttt attcgccgta aagtcaccaa
     5101 ggaagaaatg gtcattttcc gtaaatgcag gtactctgtg gcgcctcgct atatcggtaa
     5161 agaagtcgaa atcgaactct ccgataaaga agaccaagta caaatctatt ataacggaga
     5221 actgattcgg tcgcatccat taacgacaaa acagctgaac taccacgagg aagactattt
     5281 ccaaatcttg aaatccgatg tcatgagtca caaagaagac gatggaatca gagcgtatac
     5341 tcgtgaaagt ctcaagcaat atgatctggt ggaggttgcc gatgaagaat agccattacc
     5401 aagaactgat gaccaactta gagactcttg gtttgaatca tatgcgggaa tatgttccta
     5461 actacatcga agtggccaat cgagaggagc tttctttaac ggaagctctt ctcgagctga
     5521 cacgcagaga agttgatcat caaaataagc aaaaaatgaa tcgtgtggtg gcacgcgccc
     5581 gcttttccaa gagaaccagc ctggaagagt ttgattttgc cttccagcca agtatcaata
     5641 agcgcgaagt gctagactta aggcacatgg gctttgtgga aaaacatgag aacttggttt
     5701 ttatcggcag tcctggtgta ggcaagacac atctgacgat tgcattggga atcgaagcct
     5761 gtcgtcaagg ctatcggaca ctattcatca cctgtcatga gctgcttttg cgtctgcgaa
     5821 cagcctatga aaaaggtacc ctagagcgtg ttctcaaacg atacgctcgc tatgacgtct
     5881 tgattattga tgagattggc tatcttccga ttcaaaaaca ggaagctgat ttattctttc
     5941 agcttcttgc catgcgctat gaacaccgct ctacgatcat tacgacgaac attgtcttat
     6001 ctcgttgggg ggagttgttc caaagttctg agatcgcagc tgccatcctt gaccgtttag
     6061 tacatcacgt caaggtgttc aagatcacag gcaagtctta tcgtatgaga gacaagatct
     6121 aaagtgtcga ttgtcgacaa ttactattgc cgaaaaccta catttttatc ctgcccaaaa
     6181 cctacaattt taagctgccc ttgacatcaa aaagacactt cacaagctaa gtgctatcga
     6241 caattgaaac ctttgtataa attacttcta taatcagatg acgagttgga ttatacaaca
     6301 ttcaagaaat ggcagaattt tcaatggcgc tatttaacag aaagtgaagt agttgattgt
     6361 ctaccctcaa tctcttatga acttaaaatg gcttagcagt attatcaaaa gctgcttaac
     6421 aattatcaca agaaacagct agctacttcg agaaatgacc aaagaagttc cctcgaaact
     6481 tcactatctt aaaaagcctt tttcatatct gaaaaaggct tttaactagc attttcgaaa
     6541 aagtatttta atacaaaatt agagaatctt cgcacacata tcaaaacatt gaaacgattt
     6601 gcttatggat tttgcagttt taccaatatg cgcttgtgga tttttctaat caacgggtta
     6661 ataagctatg cattaaaagc tagtaaatct tactaacttt gttgatcata aatgacctta
     6721 tcagcccgat ttgacaaaga actacttttt tacaacatta ttttattttc gaataatctt
     6781 tcttacttca tttcgtatat ctggaaaaag aaaataaaca aacggaagat aaataatgaa
     6841 aatcattatt gatttaattg ccatatctaa aaatgaagaa gagaataatt gtggaagaaa
     6901 gtaataggcc gaagtagtca aagtaagatt gactataaaa aataagacaa cgttcttccc
     6961 aaagaaatag gatattttta tttcttttcg tacaaaaaat actctaaaga aaaagactaa
     7021 taattctact accacgagta cgattgtagc cgctacagcg ccataagtag gcacaaaagc
     7081 tacatttcca ataatactta caatcgcacc aatgatcatt ggataagcat actccttatc
     7141 tttttctata gcaattgcaa attggttagc aaaaactcca ccaattggac taacaactat
     7201 aattagacaa gaaataagca tgtttattgt catcggtttg aaattctccc caaaaaacca
     7261 tggaacaaat tcttttgtat tgataaacac cacactaaaa agaattaatg caataataat
     7321 cgtgtaatca aaagattttt ttgtgtaaac taaaatattt tctgattttc cctctgcctg
     7381 tgctttagat attttaggca acataacaat agtaattgat gttaagactg ccaatataat
     7441 acgagcaatt ttttgagact gatcataata agataatgct gttggatcca caaaataccc
     7501 aactatcgtt ttgtctaaag ttgtgtacac ttgcataaac aactgaggag tcaaaataat
     7561 aaaagctggt ttccacaact gtttaaaaac attagagtta aagagtggtt tacctacttt
     7621 tccgtggata ctcaaccaga aaactaaact tcctaaaaag ttagtaattg aagtaatgaa
     7681 cacataaatc cacaaatcat ctttagttga aacaaaaagg attattaaca ataccgatga
     7741 taatttgata actgtatttc taataaccac tttcgaaaat tcttcaattc cttgaaaaaa
     7801 ccaagaaata tctaatgtta gccctgcaat aaatatcaat tgaattaagt ataaattttt
     7861 atactttaca tcaaaaaaat aaatataggc tatatagaga aaggaaacac tcaagcctat
     7921 taaaaattga agaaagtaaa tattccagaa ttgtaaagat agtgcttttt tatctttcct
     7981 tgatttagcg atatttcgaa tacgaaaagg attcattccc acagcaatga cagtcattaa
     8041 aaattgtgat attgagaaaa catacccata aatccctaaa ccagttgaac ctattctacg
     8101 actaagtata ggtatagtaa gtaagggcaa aacaatcaaa aagacttgat atatcgcatt
     8161 ataaaatata tcttttactg tttttttcac tttatatccc tctctaacaa ctcaagaacc
     8221 ttttctgtac ttgcccctgt ttcataattt ccaatataat caagtaactc ttgagaactt
     8281 ttcaaaagct tttcttgttg gtttttaaaa acatcaacaa ggccataact atcttgtacg
     8341 cttataattg gtaactcact taactgtata taaaaacctc tttctaagct atattctttt
     8401 tcatcatagt taaaaagaat aattggtttt tttgttagcg caaaatcgaa aaaaatagat
     8461 gaataatctg tgattaaaac atctatctct tcaaaaagca tttcaagagg aatcccatca
     8521 ttaattaaag taatttgatg ttttttcata tattctatac ttttagaatc agttgctaat
     8581 ttactatgaa cattaggatg aaatttagtc attaaattta attcttgttg ttgcttttta
     8641 aaaaattcac gtaagttatc cacacctaac cattctagtt gcgtaattcc gttgtcctca
     8701 atattatttc gaaaagttgg agcaaataag acattgattt gtttcttttt caagtcaaac
     8761 acttgctctt tactagaggc taattcatcg tttctaggag ttcctacttc taatatttta
     8821 gaaggaacga tattgaatgc tgaaacatac ttctcagaac tatagcgatt accagataat
     8881 aaatatgtaa ttgactcact atcttttttc gcatagctta ggtaacgttt aggtaactta
     8941 tcttttgcat caaattcaat tttttttaaa ggcgtaccgt gccatgtttg aaaataaaat
     9001 tgttttttcc tttttgcata cttaatcgtt ttccgactat cgtctatcca atacttagct
     9061 gtatacaaat aaaaggcagc taaaaaagaa tcggaatcaa ttcttttaat ataatctggt
     9121 aaatcagtta taatcgcttc ttttttgatt aaccaaataa ttctgtaatt caattttttt
     9181 tcatgaattt tctctgaaat aactcttgga tttccagaat aattacgccc gccaaaactt
     9241 gaaaatacaa ttaaattttt ttgaataggt aatattttaa taaaaaccgg gaaaatattc
     9301 cttgaaaaaa atttttttat attcttcatc tcttacctca cagattcta
//
LOCUS       DAXQKX010000083         9152 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.086, whole genome shotgun sequence.
ACCESSION   DAXQKX010000083 DAXQKX010000000
VERSION     DAXQKX010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9152
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.086"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..475
                     /locus_tag="ACF3MF_002478"
     CDS             <1..475
                     /locus_tag="ACF3MF_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928390.1"
                     /translation="ATYEAVAKEMSVEPEAIMAIHKTETNLQLTNQLVSAHDVQSTFG
                     KMLAKGEPVETIDLKEACTTVAKELKVCERADGTYNFDRFYSRKANIKDVNAGILLSY
                     KAEQYYKGYKKHEHEFVPEVKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            486..2595
                     /gene="topB"
                     /locus_tag="ACF3MF_002479"
                     /pseudo
     CDS             486..2595
                     /gene="topB"
                     /locus_tag="ACF3MF_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
     gene            2611..2760
                     /locus_tag="ACF3MF_002480"
     CDS             2611..2760
                     /locus_tag="ACF3MF_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928391.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            2841..3437
                     /locus_tag="ACF3MF_002481"
     CDS             2841..3437
                     /locus_tag="ACF3MF_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HFE3928392.1"
                     /translation="MTKAMVYKLLEEFNGTLALKDAKKAGISPVTIKRMVDRGELDRE
                     YPGFFTLPGQFPDELFMAQKKYERGIISHITALDLYDLTDMIPRQIDLTVPYGYHVSE
                     KGLKEFAVELHYTKAEWYELGKIEIKSRYGNPIIAYDPERTLCDIWNPWYTVEDEIKV
                     KAIKNYMESDRKNLRKLNEYRRILPTDKTMRSYIMALN"
     gene            3450..4349
                     /locus_tag="ACF3MF_002482"
     CDS             3450..4349
                     /locus_tag="ACF3MF_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HFE3928393.1"
                     /translation="MTPTQLKAKVKNISREKEVDPQLVLRHFMMEKFLEKISESPYRE
                     NFVLKGGFLIGSKYGIENRTTKDIDTTLREMKVTKETLTTVLNEIFSTPTKEDIQFEI
                     QGMKETREADYYPGFSLRVLAHLENMRPDFKVDVTTGDSIYPATITHSHKLMFEDRTI
                     PLESYPTEQIIAEKLSATFDFLTDNSRGKDFYDLYTIPKMEKIDEKTLKDSVRNTFTR
                     RGKTDPLKIYYEKDMDVLKNSHELKDTWKKYQKSNPYAASITYDETMDSISNLMEKVI
                     HVEEKERKLAYQRHQQMNREMER"
     gene            4352..4837
                     /gene="ssb"
                     /locus_tag="ACF3MF_002483"
                     /pseudo
     CDS             4352..4837
                     /gene="ssb"
                     /locus_tag="ACF3MF_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            4882..5115
                     /locus_tag="ACF3MF_002484"
     CDS             4882..5115
                     /locus_tag="ACF3MF_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928394.1"
                     /translation="MDLLIPVIAFIDGISLGVTENPLVNRIAKGSLFLVFVYLVCSYL
                     LKRAGKDNSFWRLTKVTVAATAVILTAILPLYM"
     gene            complement(5274..5396)
                     /locus_tag="ACF3MF_002485"
     CDS             complement(5274..5396)
                     /locus_tag="ACF3MF_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HFE3928395.1"
                     /translation="MKGVSLLSAYETIQTILGFGMFTIALISLIVNMLKNDKKK"
     gene            5551..5810
                     /locus_tag="ACF3MF_002486"
                     /pseudo
     CDS             5551..5810
                     /locus_tag="ACF3MF_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328871.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            6253..6459
                     /locus_tag="ACF3MF_002487"
     CDS             6253..6459
                     /locus_tag="ACF3MF_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HFE3928396.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYCLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            6459..6710
                     /locus_tag="ACF3MF_002488"
     CDS             6459..6710
                     /locus_tag="ACF3MF_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928397.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEVLLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENLETYENEYWLTKLEN"
     gene            6726..7163
                     /locus_tag="ACF3MF_002489"
                     /pseudo
     CDS             6726..7163
                     /locus_tag="ACF3MF_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7274..7510)
                     /locus_tag="ACF3MF_002490"
     CDS             complement(7274..7510)
                     /locus_tag="ACF3MF_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928398.1"
                     /translation="MKQNTSITKNTARFNCTAALSRISISPTNSTNNKGIILFKWITF
                     FLLSYRALPVYFAPPKRRGRLERLVRNKNHFLSY"
     gene            7608..7787
                     /locus_tag="ACF3MF_002491"
     CDS             7608..7787
                     /locus_tag="ACF3MF_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928399.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDVPALKK"
     gene            7846..8202
                     /locus_tag="ACF3MF_002492"
     CDS             7846..8202
                     /locus_tag="ACF3MF_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928400.1"
                     /translation="MLKTKKNSYKLKLSILSIICLLGMIISGHLYRVAYTQFIEYKVH
                     SLGLAGDRYVEYVHYSLKCSSYILLWLIFSLFELLNLIAISSYHLDKLNTKSSRYNEV
                     FKENVKLESDLNKLKK"
BASE COUNT         3295 a         1528 c         1873 g         2456 t
ORIGIN      
        1 agctacttat gaagcagtcg caaaagaaat gagtgttgaa cctgaagcaa ttatggccat
       61 acacaaaact gaaactaatt tacagctgac aaatcaattg gtgtctgctc atgatgttca
      121 atctacgttt ggaaagatgt tggcgaaggg cgaaccagta gaaacaattg atttgaaaga
      181 agcatgtacc acggtcgcga aggaactgaa agtatgtgaa cgcgcagatg gaacatacaa
      241 ctttgatcgt ttttatagta gaaaagccaa cataaaagac gttaatgcag gaatccttct
      301 ttcctataaa gcagaacaat actacaaagg ctataaaaag catgaacatg aatttgtacc
      361 tgaagtgaaa aaggattgga atgatcaatt gaagcatgag atccagcaac aagaaatcag
      421 aaagcaaaaa cgtgcgatgt tgtttcaaca aggcagacaa caagaaaggg agtgaagtcg
      481 tcactatgaa aaccgtcatt ttagcagaaa aaccgtcaca agcgaaggct tatgccgata
      541 gcttttctaa agctacccga aaagatgggt attttgagat ccaagatcga ttgtttacag
      601 gagaaactgt gatcacgtat ggttttggtc atttagtcga gttagattcg cccgatatgt
      661 acgatgaaaa atggaaacaa tgggcattag aacatttgcc tattttcccc aatcaatacc
      721 actatcatgt tcctaaagat aagaaaaagc agtttagtgt cgtcaaacga cagctgcagt
      781 cagctgatac gattgtgatc gcgactgata gcgatcgtga aggggagctg attgcctggt
      841 caatcattca acaagcaggc gccaatcaag gaaaaacctt taaaagactt tggatcaact
      901 ccttagaaaa agaagccatt tatcagggat tccaacagtt acgagacgca gaagagacct
      961 atccaaaatt tgaagaagta caagcacgtc agatcgccga ttggttaatt gggatgaacg
     1021 gtagcccact gtatagttta ctcttgcagc aaaaaggcat accaggaagt ttttctttag
     1081 gtagagtcca aaccccaaca ctctatatga tttatcaatt gcaggaaaag attagaaact
     1141 tccaaaaaga accatatttt gaaggaaaag cccaagtaat cgctcaaaat ggcgcatttg
     1201 atgcgaagct tgatccaaat gaaacccaag cgacacaaga agcatttgaa gcctatttaa
     1261 aagaaaaagg tgttcaatta ggaaaacagc caggtacgat ccttcaagtc gaaacagaga
     1321 aaaaaagtgc ggctagccca cgtctttttt ctttatcgag ccttcagtct aaaatgaatc
     1381 aactcatgaa agctagtgcc aaagatactt tggaagccat gcaagggttg tatgaaggaa
     1441 aatatctaag ctatccgcga acggataccc cttatattac ggaaggggaa tatgcgtatc
     1501 tgttggatca cttagacgaa tacaagcatt ttttaaaagc cgaagcgatt ccgactccta
     1561 ttcatacacc gaatagtcgg tatgtgaata ataagaaagt ccaggaacat tacgcgatca
     1621 ttcctacaaa aacggttatg acagcagcgg cttttgaaca actaagtcca ctgcagcagg
     1681 ctatttatga acaagtgtta aaaacaacgg tggccatgtt tgcggaaaag tatacctatg
     1741 aagaaacaac gatcttgacg caagttcagc agcttcagtt aaaggcaatc gaaaaggtgc
     1801 cgctagatct aggttggaag aagttatttg gaaaagagag cgacggaaaa gagaaggaag
     1861 aagagccgct acttcctaaa gtgacaaaag gagaaatggt gacggtggat ctacaagttc
     1921 ttgaaaaaga aaccaagcca ccacaacctt ataccgaagg tacgttgatc actgcaatga
     1981 aaacagctgg gaaaaccgtg gatagtgaag aagcgcaatc catattgaaa gaagtggaag
     2041 gaatcggtac agaagcgaca cgggcgaata ttattgaaac cttgaaacaa aaggaatata
     2101 tcaaggtaga gaaaaataag ctcgtggtga cgaataaagg gattttgctt tgccaagccg
     2161 tggaaaaaga gccgctgctt acgagcgccg aaatgaccgc caaatgggaa agctacttgt
     2221 taaagatcgg tgaacgaaaa ggaacacaaa ccacttttct agccaatatc caaaaatttg
     2281 tctctcactt attggaagtc gtaccagggc aaatccaatc cactgatttt ggatcgacgt
     2341 tacaagaagt gaaagcagcc agtgaaaagc aagaagccgc gcgtcattta ggaatttgtc
     2401 caaaatgcca ggaacaagaa gtcttactct atcaaaaggt ggcagcttgt acgtctgaag
     2461 cctgtgattt taaaaggtca gaagggttca tttgaagcaa cgattgtttt aaaagaagac
     2521 ttcactacag gctttgaatt ttctgaaaag aaaaaaacga acttcaagaa aagaacacgc
     2581 cgcactgcaa aataatggag ggttaatctt atgcgtaata ccacacacaa acaacaagaa
     2641 atcgaaaatc aaaaagccaa aattcgttca gaacaggaaa aaatgcgtgc cagcaaacga
     2701 agactgcagc aattgaagaa ccagcagagg attcaaaaag aaatcgaatt agatcgataa
     2761 aatcttccta actattgtat acgtataaac ttatgttata ctgtttttat aagtttatac
     2821 gtatacaaag gagggagaaa atgacaaaag caatggtata caagctgcta gaagaattta
     2881 atggaacttt ggctttgaag gatgccaaaa aagcgggcat ttctcctgta acgatcaaac
     2941 gtatggtaga tcgaggggag ctggatcgag agtatccagg ttttttcacc ttacctggtc
     3001 aatttcctga tgaattgttt atggcgcaaa aaaaatatga acgcggcatt atttcacata
     3061 ttaccgcgtt agatttgtat gatttaacag atatgatccc tagacagatc gatctgactg
     3121 taccttacgg ttatcacgtt tctgaaaaag gattgaagga attcgcagtt gagctacact
     3181 atacaaaagc ggaatggtat gaattaggta agattgaaat aaaaagtcgc tatgggaatc
     3241 ctattatagc ttatgatcca gaaagaactt tatgtgacat ttggaatccc tggtataccg
     3301 ttgaggatga aatcaaagta aaagcaatca aaaactatat ggagtcggac agaaaaaatc
     3361 ttagaaaatt gaatgagtat cgacgaattt taccaacaga caaaacgatg cgttcttata
     3421 ttatggcttt aaattaaagg agaagataca tgacacctac gcagttaaaa gcaaaagtga
     3481 agaatatttc tagagaaaaa gaagttgatc cgcagcttgt tttaagacat tttatgatgg
     3541 aaaaattctt ggaaaaaatc tcagagtctc cttatcgtga aaattttgtg ttaaaaggcg
     3601 gcttcttgat tggctcaaag tatggcattg aaaatcgcac aaccaaagat attgatacga
     3661 ctttacggga aatgaaagta accaaagaaa cattaacaac ggttctaaac gaaatttttt
     3721 caacgccgac gaaagaagac attcaatttg agattcaagg aatgaaagaa acgagagaag
     3781 ccgattacta tccaggattt agcttacgtg tgctggcaca tttggaaaac atgcggccag
     3841 attttaaggt agatgtgact acaggtgact cgatctatcc tgcaacgatc actcacagtc
     3901 ataaattgat gtttgaggat cgaacgattc ctttggaatc ctatcctaca gaacaaatta
     3961 ttgctgaaaa attaagtgca acctttgatt ttttaacaga taattcgaga ggaaaagatt
     4021 tttatgatct ctatactatt cctaaaatgg agaagatcga tgagaagacc ttgaaagata
     4081 gtgtgagaaa tacatttaca cgtcgaggaa aaactgatcc gttaaagata tactatgaaa
     4141 aggatatgga tgtactgaaa aatagtcacg agctaaaaga tacctggaag aaatatcaaa
     4201 aaagcaatcc ttatgctgcg tcgatcacgt acgatgagac aatggattcg attagtaatt
     4261 tgatggaaaa agtgattcac gtcgaagaaa aagagcgaaa actagcttat caaagacacc
     4321 aacagatgaa tagagaaatg gagagataaa gatgattaat aatgtgacat tagtaggacg
     4381 cttaaccaaa gatcctgatt tacgttatac cgcaagtggt actgcagtag cgacttttac
     4441 cctagccgtc aaccgaaatt tcacgaatca aaacggcaat tgagaagccg attttattaa
     4501 ctgcgtgatt tggcgcaaac cagcagaaac aatggcgaca ttagctaaaa aaggtagctt
     4561 gattggtgta gttgggcgga ttcaaacgcg gacttacgac aaccagcaag gacaacgtgt
     4621 atatgtgact gaagttgtag cagataactt tcaactatta gaaagtaaag cagcgacaga
     4681 gagccgtgcg cacgctgatc aatcgtccac cagtccaagc accgccacct ttgaacaacg
     4741 gaatacagcg acgcctaaca acaatggatt gaacgcttca cagaatccat ttggtggaca
     4801 atcaatcgat attagcgatg atgatctacc gttttagttt gagaaagaag gagtaagcat
     4861 ggcaaaaaaa ttagtctgac gatggatcta ttgatacccg taattgcatt tatagacggg
     4921 atttctttgg gcgtcactga aaatcctttg gtaaatagaa ttgcgaaagg atcactattt
     4981 cttgtattcg tgtatcttgt ctgttcttat cttttaaaaa gagcaggaaa ggataattcc
     5041 ttttggcgat tgactaaagt cacagtagca gcgacagctg ttatacttac ggctattcta
     5101 ccgctttata tgtagagtta acgggaaatc gttgaacttc ttgcgaaata ttgctataat
     5161 gaacatgaaa aagaggagtt gcgctaacaa cccctcatta acagcaccga ttaaagaacg
     5221 gtggcagaat attagttatt tggaaataac cgctgacctg ctaaagtaga cggttatttc
     5281 tttttgtcat ttttaagcat atttacaatc aaactaatca aagcaatggt aaacatacca
     5341 aaaccaagaa tggtttgaat tgtctcatat gcggacaaaa ggcttactcc tttcatagat
     5401 tttagcactt acattcataa gcaccaccac ctttccagaa gtcgccaccg tcttcaaact
     5461 ttactgtctt gactattata gcatatctaa aatcgaataa aaattctcaa ttttagctgt
     5521 ttttgctata attttagcga ggtgatcgtg atggaacaat atattggttt actcgataaa
     5581 ttagggtgat caagacacag ccattgcttg tgcgatttac attacgcacg agtcatgaac
     5641 caatcaattg tgtagtggcc aatatagaaa tagcggataa attgctgatt ttggaagaag
     5701 gcaagtatac tatttcagtg acaggtcact tcaataaacg aaagcaacta gtcattgaat
     5761 caatgcaaat tagaaaccct gatcatttta cgcgatcgat gagcatataa aagaagagct
     5821 gcagtcctaa atgaggattg tagctctttt tgttttacat agaaacagta aaaatgaaaa
     5881 ggcctgttta ggaaggcaca agcgccttct caattgaaag acctttctct cactccaacc
     5941 gccaccgccg ttcgagaaga aaggaagtga acgctacgcg ttcactaaga taaagggtct
     6001 tgcatagcaa gacaaaatag aaaaaatttc ctctcaccaa aaggttcgct cctgttcgtt
     6061 atctctttat tgatttgtca gaccggcaac aagttgcctt ttatcaccaa aaagcgacaa
     6121 ggacaagggt aaatggcacg ctgcgcgccc ttgtcttgtc gcttttcgtt gattcattct
     6181 ggccaacaaa tcaataaaga aagaactaac gaaaggaagt aaaacctttc ctaagaggag
     6241 gcagaatcaa tcatgcgaaa gaaatttgat tattggggtg ttcccttcag cgaattattc
     6301 ccaaactatc atgcaccaca tactgtcgaa tgcgattgtg gagaaagagc gaaatgtatc
     6361 aaaagctatt gtttgtatca atgtccaaca tgcgggaaaa aatatacctt gtcttatggc
     6421 gattatattt taattgatga gaaaggaaag aaacgctgat gaaaacacaa cacaaattat
     6481 tgactgtaaa agaagtcgtt caaattttgg tggacaaaga agtcatttct gaaaaagtag
     6541 cagaagtttt acttattccg cggtactgga cgatagaaac ccctttagta gaggatgcac
     6601 cgactatgct atttgaagac ctagtgaaga ttgcaggata tgaactgcat tatcaagaaa
     6661 acttggaaac ttatgaaaac gaatattggt taaccaaatt agagaactaa aaaggagaaa
     6721 aaaatatggc tcaaaattac tatgacgaat ttgtcaaatt acctttggat aaaatggcac
     6781 aaaaaatgga ggatatgacg ttcctataca acgaaacacg tgttccaaaa aaacattata
     6841 aagaaaaatt gtcggtagct gtggaagaaa tgattgaata aggtgtcgaa atgaatctta
     6901 ttgcgacgta ctatcgaaca ctggaagaac tgaaaaagca aaatgcaaaa tggtttttcc
     6961 aagccttact atgcttggaa gtaggtgtca aaccaagcac tattaaacct tctgaatacc
     7021 aagctttaga actaacgtat gcgaaattta tcgaaacgaa aaaagccaag actgtttcaa
     7081 gtgaatggtt agattatttt gaaaatatca ataagtatgg cgcatattac accatgaaaa
     7141 aggaagacaa cgaaaatgaa taaggtgatt tatcaactaa caacggattc catatcaacg
     7201 atttgaaaga aaaaaaggtc aataatcatt tataccgaaa agtgagaatg tgtgaaacaa
     7261 ggacaaaaaa agcctagtaa ctaaggaaat ggttcttatt tcgcaccaat cgctccaacc
     7321 gcccccgccg cttaggtggt gcgaaataaa cgggcaaagc ccgataactt aagagaaaga
     7381 aggtgatcca tttgaacaag attattccct tattgttagt actgtttgtt ggcgaaatac
     7441 ttatgcgaga tagtgcagct gtacagttaa acctcgctgt atttttggta atactggtgt
     7501 tttgtttgat cttttggcgg tttgtattag tcctcgtgag tctactattc aagatgattg
     7561 cagccatatt tttcataggg ttatttcgat gaaaggagtg agtaccaatg ccaattgcaa
     7621 taggaaataa acggttaccc gtgacattag atgaaaagag acaaaaagaa ttgcagcaac
     7681 taaagcagaa gtatggcaaa agtgaatcta agattatgtg tattgcgtta gatctattga
     7741 tcgcgcaaga aaaagcagga tttgatgtac cagcgctaaa aaagtgacgt cactttttaa
     7801 tttgatctat ataagtgata tcacttttac caaggaggga attaaatgtt aaaaactaaa
     7861 aagaattcgt acaaattaaa gcttagtata ctatctatta tttgtctttt aggcatgata
     7921 attagtggtc atttgtatag agtggcatat acgcagttta ttgagtacaa ggttcactct
     7981 ttaggattag ctggggatcg atacgttgaa tatgtccatt attcattaaa atgttcttca
     8041 tatattcttc tttggcttat tttttcattg tttgaattgc taaatttaat agcaatatct
     8101 tcatatcact tagataagct aaataccaaa tctagccgtt ataacgaagt gtttaaggaa
     8161 aatgtgaagt tagaaagtga cttaaacaag ctaaaaaaat aaaaagaaga aaacataagt
     8221 taactaaaat tattttatta agaatgatgg aatataagga taaggttacc aacataacga
     8281 tcattacttc tctgatatgc tatggacttc tatcaatcag tattttgtct atagattatg
     8341 gagtaactat actgcaagcc ttagttttgg ctatgcctat gtatctatct ttgtttatca
     8401 tgcatgaaat atataagcta tttgttttat caaaaaatgt agaaatacgg gtaaatattt
     8461 tggtgaatag ttatcaaaaa gaactcaaag aaagaagacg gtggcggtat ttattgaaag
     8521 gatgaaaaag taggatttga catactggta ttcagaaagt gccgtcactt ttaaaacaat
     8581 ggaaaaggtg gagataagat gaagaaaaaa caaactaaac tatcattagc agatatttaa
     8641 cacagttaac cgcaactgaa gatggtgttg ttgaatttga acaatctgaa attgcggtag
     8701 tagatgatcg ttaccttaaa atgccttact tctttgacca agcaaaggtc atttgccttt
     8761 gtcactacga tggggtacgt gattttaggc gttaaaaagt agtgattata tcaactttac
     8821 gagtaaatat aaatttagac atgaaactga attatccaat ggaaaatcat ggtttataat
     8881 ctagaaaaat tatagtaatg attggattat atatattctt tcgtattttc gtacaactgt
     8941 agcttgtcaa aattgagaaa tttaaccgat taggtacttt acatcgttat ttgggtaatt
     9001 tctaaaacat gaagcttacc aacgaataaa ctgagactat cttattaatt gatcaatata
     9061 agaaaatatc tttgaggaga tgatgtacta tgttttcgtc tatccacgat tggttaggtg
     9121 gtcttttcgg cggtggaggt aaaggttttt aa
//
LOCUS       DAXQKX010000084         8883 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.087, whole genome shotgun sequence.
ACCESSION   DAXQKX010000084 DAXQKX010000000
VERSION     DAXQKX010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8883)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8883)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8883
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.087"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            4..1458
                     /locus_tag="ACF3MF_002493"
     CDS             4..1458
                     /locus_tag="ACF3MF_002493"
                     /EC_number="1.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018478 - malonate-semialdehyde
                     dehydrogenase (acetylating) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-acylating methylmalonate-semialdehyde
                     dehydrogenase"
                     /protein_id="HFE3928401.1"
                     /translation="MTRFLRNYIDGRWVASRSTEFEEVMNPATEEALANVPLSSKAET
                     AEAVKAADAAFQTWKKVPVPVRGRYLFKLHQLLTDHKSELARLITLENGKSLSESLGE
                     VQRGIENVEHAAGITNLMMGDSLSTAATDIEITNYRYPIGVIGGITPFNFPMMVPFWI
                     FPMALAAGNTVVLKPSEKTPLLMEKIVELVEKAGFPSGVFNVVYGAHDVVNTLLQDPL
                     VKGISFVGSKNVGEYVYREGTKNLKRVQALTGAKNHVVVLKDANIDRAVKDLIGGAFG
                     SAGERCMAASVIVLEEEIADQFVEKFKAAAKAIKIGNGLDEGVFLGPVIRKDAQQRTF
                     DYIQKGVDEGAKLVLDGRENIPEKGYFVGPTIFDNVTMDMKIWQDEIFAPVASIVRVK
                     DLMAAVELTNESEFANGSCLYTNNASAIRYFRENVDAGMLGVNLGVPAPMAWFAFSGW
                     KHSFFGDLHANGKDSVEFYTHRKVVTARYAQSEI"
     gene            1552..2694
                     /locus_tag="ACF3MF_002494"
     CDS             1552..2694
                     /locus_tag="ACF3MF_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HFE3928402.1"
                     /translation="MPANLRIGGGTIQFLMEESEQLGNKPLIISDTVMEQTGHLQKIK
                     ELLGKTDDQLAEYTDIQAEPTQENVYDALKLFQKHQCDHIIAFGGGSCLDTAKVVAVL
                     AANQLSLEAIHARNFDQLQAGIPLIAVSTTAGTGSEVTDVAVITNTKTAVKMMMKDLV
                     FMPQISIVDSDFTKTVPPKVTAATGVDALCHALESYVSVKANEVTQLFSLEAMKKILN
                     TLSQAYENSDDTEAREQMSLASTEAGIAFSNASVTLIHGMSRPVGALFHIPHGISNAM
                     LLPVFFEFSKDAIQTELATIARFIYPAAEDLSLEEAADYLIKKIQELCEQLSIPTIRD
                     YGIDQQAFMAALDKMAADALTSGSPQNNKKVPSHSQIKELYVQAYG"
     gene            2807..3814
                     /locus_tag="ACF3MF_002495"
     CDS             2807..3814
                     /locus_tag="ACF3MF_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFE3928403.1"
                     /translation="MRVKVGVIGTGAIGIEHIDRINQKTQGAYVTAVSDINVKAAKEV
                     AKRVDAKFFETGEALIASEDVDVVVVTSWDPTHEQYVLEAIKHGKYVFCEKPLAMDAA
                     GCRRIVDAEVAYGKKLVQVGFMRRYDRGYIELKEAIESKQYGEALMMHCAHRNPSADE
                     NYTTPMAISNTAIHEIDVLRWLLNEDYESVQMILPKKTSNSHADLHDPQLLIFQTKSG
                     VTIDLEIFVNCRFGYDIKCDVVFETAEVGMTDPAYTRIKSEEKNYTPVSPDWQTRFLD
                     AYDYEFKLWIDSIKNDAVVGPTAWDGYVAAITMMACHESRETKTKVMIQMDERPALYN
                     E"
     gene            3838..4863
                     /gene="iolG"
                     /locus_tag="ACF3MF_002496"
     CDS             3838..4863
                     /gene="iolG"
                     /locus_tag="ACF3MF_002496"
                     /EC_number="1.1.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050112 - inositol 2-dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_process: GO:0019310 - inositol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="inositol 2-dehydrogenase"
                     /protein_id="HFE3928404.1"
                     /translation="MNNIRVGIVGLGRLGKVHAQNLATGVSCCELTAACSLVETELAF
                     AQKKLGVKHTFSSYEEMVKSSVIDAVFIVSPSGFHCDQVRLAMENGKHVFTEKPLGLE
                     VEDIKKTQKVIEEHPEQVFMLGFMRRYDESYQYAKKMVEDGEIGEITLIRCYGIDPSE
                     GLESFVKFAMNNDSGGLFLDMAIHDIDLVRWFTGQEVDQVWAIGKNAAYPELDQAGEL
                     ETGAAMMSLSDKTIALLVAGRNAAHGYHVETEIMGTKGMLRVAQAPEKNLVTIMNDQG
                     IIRPCSQNFPERFREAFIREAQEFVSCIQEKRQPAVNAEDGLQSTKIALACQESFDTK
                     SLVQLKK"
     gene            4880..5770
                     /gene="iolE"
                     /locus_tag="ACF3MF_002497"
     CDS             4880..5770
                     /gene="iolE"
                     /locus_tag="ACF3MF_002497"
                     /EC_number="4.2.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010777829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050114 - myo-inosose-2 dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0019310 - inositol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="myo-inosose-2 dehydratase"
                     /protein_id="HFE3928405.1"
                     /translation="MTKQIQLAIAPIAWTNDDMPELGSENTFEQCISEMALAGFTGTE
                     IGNKYPKDPEVLEQYLNIRGLKVASAWFSAFLTTKPFEETAEAFKAHRDFLHAMGAKV
                     IVVAEQGHSIQGIMTAPVFDDKPVFTDEEWKKLAEGLEKLGDLAHEKDMEIVYHHHMG
                     TGVQTTEEIDRLMEMTDPDKVKLLFDTGHLVFSGENPIAVYNRHQDRIKHIHFKDIRQ
                     ETAEEVEKEKDSFLNGVKKGVFTVPGDGMIDFTPIWTAIHASDYEGWIVVEAEQDPAK
                     ANPFEYAVKARSYIREVTGL"
     gene            5793..7388
                     /locus_tag="ACF3MF_002498"
     CDS             5793..7388
                     /locus_tag="ACF3MF_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute:sodium symporter family transporter"
                     /protein_id="HFE3928406.1"
                     /translation="MNLFSIISFLVIVICVWLFAYSRSRSVDTSGSEGFFMGGRSLTA
                     LPIAGTIIMTNLSTEQIVGQNGQSYHAGMEVMAWEVTATIAIVALAVIFLPKYFKYGI
                     NTISDFIETRYDTVTKRIISILFIVTYMTSFLPVVLYSGSLVFNKIFHIDELLGVQPI
                     VAIIIVAMAIGIVGILYLLIGGLSLSANSDSIYGVGLLACGLLVPILGLMKLGDGSFV
                     GGIEHVVVNTPWLLNSVGSIDSAVVPWPTLFTGMLFNNLYFWCTNQMIVQKALSGKNL
                     AEAQKGAFLVGVFKILGALFLVFPGIVARNIFGDSLMSNPDNAYPFLVSEVLPKMIFG
                     IFAAVIFGAILSSFAGALNATSTLFSLDFYKPLINKKANDKQIARAGKTVTVVVGIIS
                     IIVAPFISFAPAGLYQFVQEFNGLYNMPLLVIILFAFYSKKATAFGAKTTIAVHIVLY
                     ALSKMLFQNIHFLYVLTALFVLDIIILMVVSKLKPDGEFVLNSFDTKVDIEPWKYTKV
                     TAIALVVIVILTYVAFSPIGFAG"
     gene            7404..7718
                     /locus_tag="ACF3MF_002499"
     CDS             7404..7718
                     /locus_tag="ACF3MF_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFE3928407.1"
                     /translation="MHKDLLIICETGISASLLVSKMLETIRAKNLSYEIDYATIRNVE
                     EKLNYKDYDVLLLTPQVARSEEKVKEIIKKEKCTAQIVYIKQEDFRYMNIENIIASIE
                     ED"
     gene            8179..>8883
                     /locus_tag="ACF3MF_002500"
     CDS             8179..>8883
                     /locus_tag="ACF3MF_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFE3928408.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKELKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFI"
BASE COUNT         2708 a         1618 c         2090 g         2467 t
ORIGIN      
        1 taaatgacaa gatttttaag aaattatatt gatggtcgtt gggtcgctag tcgctcaaca
       61 gagtttgaag aagtaatgaa tccggctaca gaagaagcgc tggcgaatgt accgttgtct
      121 agcaaagcag agacagccga agcagttaaa gctgccgatg ctgcgtttca aacttggaaa
      181 aaagttcctg ttcctgttcg cggacgttat ctgttcaagc tgcatcagct tttaacagat
      241 cataaaagtg aattggcgcg tttgatcacg ctggaaaatg ggaaatcatt gtccgagtca
      301 ctgggagaag ttcaacgagg aatcgaaaat gtggagcacg cagcgggaat caccaattta
      361 atgatgggag attctttatc aacagcggcg actgatattg agatcacgaa ttatcgttac
      421 ccaatcggag taatcggagg gatcacaccg tttaattttc caatgatggt gcccttctgg
      481 atcttcccga tggctctggc ggcaggaaat acggtggtgc tgaagccttc agaaaaaaca
      541 ccattgttga tggagaaaat tgttgagctg gttgaaaaag caggctttcc tagcggtgtt
      601 tttaatgttg tctatggtgc ccacgatgtt gtcaacacat tgctgcaaga tccactggta
      661 aaaggcatca gctttgtagg atcaaaaaat gtcggtgaat acgtttaccg tgaaggaaca
      721 aaaaatctaa aacgggtaca agcgttgact ggagcgaaaa atcatgttgt tgtgctgaaa
      781 gatgccaata ttgatcgggc agtcaaggac cttattggcg gagcttttgg ttctgctggt
      841 gaacgctgca tggcagcctc cgtcattgtt ttggaagagg aaatcgcgga tcagtttgtt
      901 gaaaaattta aggctgcggc aaaagcgatc aagatcggca atggcttgga cgaaggggtc
      961 tttttaggac cagtgattcg aaaagatgca cagcagcgga cctttgacta tatccaaaaa
     1021 ggggtcgatg aaggagcgaa actggtacta gatggtcgcg aaaacattcc agaaaaaggc
     1081 tattttgttg gaccaacgat ttttgataat gtcacgatgg atatgaagat ctggcaggat
     1141 gagatttttg ccccggtcgc atcaatcgtg cgggtaaaag atttgatggc agccgttgag
     1201 ctgacgaatg aatctgaatt tgcgaatggt tcgtgtctgt ataccaacaa cgcatcagcg
     1261 attcgctact tcagagaaaa tgttgatgct gggatgctgg gggtcaatct tggggtgcct
     1321 gcaccgatgg cttggtttgc cttttcaggc tggaagcact ctttctttgg tgatttgcat
     1381 gccaatggca aagacagtgt tgagttttat acccatcgga aagttgttac agcacgttat
     1441 gcgcaaagtg agatttaaag atttgcttcg aagctctgtt aaagagcttc gaggattctg
     1501 ttataggcta taagccagag agaggttttt tctgtgaata ttcaactgaa aatgcctgcc
     1561 aatttaagaa ttggcggcgg aacaatccaa tttcttatgg aagaatcaga acaactaggc
     1621 aacaagccgt taatcattag tgatacggtt atggaacaga ccgggcatct tcaaaagatc
     1681 aaggagctgt tgggaaaaac agatgatcaa ttagcggagt atacagacat tcaagccgaa
     1741 ccgacgcaag aaaatgttta tgatgcgctg aagctttttc agaagcatca atgtgatcat
     1801 atcattgctt ttggtggcgg cagctgtctg gatacagcca aggtggtagc cgttttggct
     1861 gctaatcaat taagtctcga agcgattcat gcaagaaatt ttgatcagct gcaagcgggc
     1921 attccgctga ttgcagtgtc aacaactgct ggaactggtt cggaagtaac cgatgtggca
     1981 gttattacca atacaaaaac agcagtcaaa atgatgatga aggatctcgt tttcatgcca
     2041 cagatctcaa tcgttgactc tgattttacg aaaactgtac caccaaaagt aaccgcggca
     2101 acgggagtcg atgcgctatg tcacgctttg gaatcttatg tttcagtcaa agccaatgaa
     2161 gtaacgcaac tattttcact ggaagcgatg aagaaaattt tgaacacgct ttctcaggca
     2221 tatgaaaata gcgacgacac tgaagccaga gaacaaatga gcttagcttc aacggaggcg
     2281 gggattgcct tttcgaatgc gtcagtcaca ttgattcatg gaatgagtcg accggtgggg
     2341 gcactttttc acattcctca tgggatatca aatgcgatgt tattgccggt cttttttgaa
     2401 ttctcaaagg atgctattca gactgagtta gcgacgatcg ccagatttat ttatccggca
     2461 gccgaagatt tatcgctgga agaggctgcg gattatctga ttaaaaaaat ccaagagctc
     2521 tgtgagcagc tgtcgatccc aacgattcga gattatggta ttgatcagca agcgtttatg
     2581 gcagccttag acaaaatggc cgcggatgcg ttgaccagcg gaagtccgca aaataataaa
     2641 aaggtgccta gtcatagtca aattaaggaa ttatacgtac aagcttatgg gtagtaaaag
     2701 gcggagcaaa gagagggctc taccttttaa gaataaaagc tacacaggaa taattttgta
     2761 agcgcatact atgtgtgctt aaacaacaga acagggggat aagtaattga gagtaaaagt
     2821 aggcgttatc ggaacaggtg caatcggcat cgagcatatc gacaggatca atcagaaaac
     2881 acaaggggct tatgtgacag cagtctcaga tatcaatgta aaagctgcta aagaggttgc
     2941 caaacgtgtc gatgctaaat tctttgaaac cggagaagca ttgatcgctt ctgaagatgt
     3001 ggatgtcgtt gttgtgactt cttgggaccc gacccatgag cagtatgtgt tagaagcaat
     3061 caagcatggg aaatatgttt tctgcgaaaa gccattagcg atggatgcag caggctgccg
     3121 ccggatcgtt gatgcggaag ttgcttatgg gaagaaattg gttcaggttg gcttcatgcg
     3181 ccgctatgac cgcggctaca ttgaactgaa agaagcaatc gaatcgaagc aatacggaga
     3241 agcattaatg atgcattgtg cccatagaaa tcctagcgca gatgaaaact acacaacacc
     3301 gatggcgatc agcaacaccg cgattcatga gattgatgtg cttcgctggt tgctaaatga
     3361 agattatgaa tctgttcaaa tgatcttgcc gaaaaaaacc agcaactccc atgccgattt
     3421 gcatgatccg cagctgctga tctttcaaac aaaatccggt gtaacgattg atttggaaat
     3481 ctttgtgaat tgccgctttg gctacgatat taaatgtgat gtggttttcg aaacggcaga
     3541 agtaggaatg acggacccag cctatacacg aattaaatcg gaagaaaaaa attacacacc
     3601 tgtttcacca gattggcaga cccgcttttt ggatgcctat gattatgaat tcaagctgtg
     3661 gatcgattcg atcaaaaatg atgcggttgt cggtcctacc gcttgggatg ggtatgtagc
     3721 agcgatcacc atgatggctt gtcatgagtc tcgtgaaaca aaaacaaaag taatgattca
     3781 aatggatgaa cgaccagcac tatacaatga gtaattctca gaaaacggag gtatttcatg
     3841 aacaacatta gagtaggcat cgtcggttta ggaagattag gaaaagtaca tgcacaaaat
     3901 ttagcaacag gtgtcagttg ttgtgagctt acggctgcgt gcagtttagt tgaaacagaa
     3961 ttagcattcg cacagaagaa attaggcgtc aagcatactt tttccagcta tgaagaaatg
     4021 gtcaaaagtt ccgtgatcga tgcagtcttt attgtttcac catcaggctt tcactgtgac
     4081 caagtccgct tggcgatgga aaatggcaag catgtcttta ctgaaaaacc attaggcctt
     4141 gaagttgaag atattaaaaa gacccaaaaa gtcatcgaag agcatcctga acaggtcttc
     4201 atgttaggct tcatgcgccg ctatgatgag tcgtatcagt atgcgaagaa aatggtagaa
     4261 gatggcgaaa tcggcgaaat cacactgatt cgttgttatg ggatcgatcc gagcgaaggc
     4321 ttggaaagct ttgtcaaatt tgccatgaat aacgacagcg gcggcttgtt cttagatatg
     4381 gcgatccatg atattgattt ggttcgctgg tttaccggcc aagaagtcga tcaagtgtgg
     4441 gcgattggga aaaatgcggc gtatccagaa ttggatcagg ctggtgagct tgaaactgga
     4501 gccgcaatga tgagcctgag cgataaaaca atagctttac tagttgccgg cagaaacgca
     4561 gcccatggct atcatgtcga aacagagatc atgggaacca aaggaatgct gcgggtagcg
     4621 caagcgcctg agaaaaatct tgtgacgatc atgaacgatc aagggatcat ccgtccatgt
     4681 tcacaaaact tcccagaacg attcagagaa gccttcattc gtgaagccca agaatttgtc
     4741 tcatgtattc aagaaaaacg tcaaccagcg gttaatgcag aagatggatt gcaatcaact
     4801 aagatcgcgt tggcttgtca agaatcattc gatacgaaga gtttagtaca actaaaaaaa
     4861 taagcaggag tgtgagaata tgaccaaaca aattcaatta gccatcgcac caatcgcgtg
     4921 gaccaatgat gatatgcccg agcttggtag tgaaaatacc tttgaacaat gtatcagtga
     4981 aatggccctt gctgggttca ccggaacaga gattggcaac aaatatccaa aagatccaga
     5041 ggtgttggaa caatatttga atattcgcgg cttaaaggtt gccagtgcat ggttcagtgc
     5101 gtttctgaca actaaacctt ttgaagaaac tgccgaagcc ttcaaagcac atcgggattt
     5161 cttacatgcg atgggcgcta aagtcatcgt agtagctgag cagggtcata gtatccaagg
     5221 gattatgaca gcgccagtct ttgatgataa accagttttc actgatgaag agtggaaaaa
     5281 actggcggaa ggattagaaa aattagggga tttggcccac gaaaaggata tggagatcgt
     5341 ttaccatcat cacatgggta ccggcgttca aacgacggaa gaaatcgatc gtttaatgga
     5401 aatgactgat ccagacaaag ttaaattatt gttcgatacg ggacatttgg tcttttctgg
     5461 tgaaaatcca atcgcggttt acaaccgtca tcaagatcgt atcaaacaca tccatttcaa
     5521 agatattcgt caagaaacgg ctgaagaagt agaaaaggaa aaagacagct tcttaaacgg
     5581 cgtgaagaaa ggcgtcttca cggttcctgg tgatgggatg attgatttca ctccaatctg
     5641 gacagcaatc catgccagcg actatgaagg ctggatcgta gttgaagcag aacaggaccc
     5701 ggctaaagcc aatccatttg aatatgcagt caaagccaga agctacattc gagaggtcac
     5761 cggtctttaa tctattgaaa aggagctaga cgatgaatct tttttctata atcagtttcc
     5821 tagtgattgt catctgtgta tggttatttg cctattctag atccagaagt gtcgatactt
     5881 ctggatcaga agggttcttc atgggagggc ggagcttaac tgctttgcca atcgccggca
     5941 cgatcatcat gacgaacctg tccaccgaac aaatagtcgg acaaaatggt caaagttatc
     6001 atgcagggat ggaagtaatg gcctgggaag taactgctac gattgcgatc gtagctttgg
     6061 ctgtgatatt cttgccaaaa tattttaaat acggcatcaa tacaatctca gatttcatcg
     6121 agactcgtta tgatacggtt accaaacgaa ttatttcgat cttatttatt gtgacctata
     6181 tgacttcttt cttacccgtg gttctttatt ctggatcgct ggtgttcaat aagatcttcc
     6241 atattgatga gctgctgggc gtccagccga tcgtcgcgat cataattgta gcgatggcaa
     6301 ttggtattgt cggcatcctc tatctgctga tcggcggctt gtcgttaagt gccaatagtg
     6361 actccattta tggagtcggt ctgctggctt gtggtctgct ggtcccaatt ttaggcttaa
     6421 tgaagcttgg tgacggcagc tttgttggcg ggatcgaaca cgttgtggta aacacgccat
     6481 ggctgcttaa ctctgtggga tcgatcgact cggctgttgt tccatggccg acactattta
     6541 cagggatgct gtttaacaat ctgtatttct ggtgtaccaa tcaaatgatc gtccaaaaag
     6601 cattgtccgg caagaattta gctgaggcac aaaagggcgc tttcctagtc ggcgtcttca
     6661 aaatcttagg tgcgttattc cttgtctttc cagggatcgt cgctcgcaat atttttggcg
     6721 atagtttaat gtcaaatcca gataacgcgt atcctttttt agtcagtgaa gtattgccta
     6781 aaatgatctt tggtattttc gccgctgtta tctttggcgc gatcttatca tcatttgcgg
     6841 gagctttgaa cgcgacatcg accttgtttt cactggattt ttataaaccg cttatcaata
     6901 agaaagcaaa tgataagcaa atcgctcgtg ctggtaaaac agtaacggtc gttgtgggga
     6961 ttatctccat tatcgtagcg ccattcattt cttttgcacc ggctggattg tatcagttcg
     7021 ttcaagaatt caatggacta tacaacatgc cgctgctcgt gatcattctc tttgcctttt
     7081 attcaaaaaa agcaactgct tttggggcaa aaacgacgat tgccgtgcat atcgtcttgt
     7141 atgcactatc aaaaatgctt ttccaaaata tccatttcct ttatgttttg acggcattat
     7201 tcgttctgga cattatcatt ttgatggtgg tttccaaatt gaaacctgat ggagaatttg
     7261 tgttgaactc attcgataca aaggtcgata tcgagccttg gaaatacacc aaggtgactg
     7321 ctatagcatt ggtagtcatt gttattttaa cttatgtggc attttcacca attggctttg
     7381 caggctaaaa acaggagggt attatgcata aggatctatt gattatttgc gagaccggaa
     7441 tcagtgcgtc gctgctcgta tcaaaaatgc ttgaaacgat cagagccaaa aatctatcgt
     7501 atgagataga ttatgcaacg atccgaaacg ttgaagaaaa actgaattat aaagactatg
     7561 acgttttact tttaacgccg caggtcgcac gttctgagga aaaagtaaaa gaaatcatca
     7621 aaaaggaaaa atgtaccgct cagatcgttt atatcaaaca agaagatttt cgttatatga
     7681 atattgaaaa catcattgca agcatcgaag aagattaacg agaatctttg attattgagt
     7741 gtcgaggagg tggtatatga aaagatggca tgttcgcccc gatcacccca atatgaaggg
     7801 cggacttatt agaaataccc aatcttgtat ttattcaata gggtaagcgg acctcaatag
     7861 ccagctcatc cccaaaaagt cgaatggaga cacttaaatg agtgtaccta ttcgactttt
     7921 tgagactcta agtcaaatcg tgttgttctc attaaatcac tgaaaggaaa tgcttcggcg
     7981 tttccttttt tctttttgtt tttcttcgtg ttttgaaaat tacttactat ttactatacg
     8041 agtagtttca aataattttg acatcctaat cttcaacaac agaaaaaaat ctaaattata
     8101 aaatttaggg ttgactaaaa tataattttt gtataccata tgatcgtgat aatcattatc
     8161 atttagaagg agaaagttat gttagaagtg aaaaagctta atgtttgtta taacgatttt
     8221 ttagcattga acgagatttc tttaaaaata caagaaggtg ctttaacagg tattattggt
     8281 ccaaatggtg ctggaaaatc tacattgctt aaagcaatgt taaatattat ccctcatcag
     8341 ggagaggtct ccattaataa tgaagatatc aataaaaaac tggtgaagat tgcatatgta
     8401 gagcaaaaag ctgatattga ttttactttt ccaataaaag taaaagaatg tgtatctatg
     8461 ggaacatatg ccggaatgaa agtttttcaa agaattaaaa atgcagaatg gcaaagagtt
     8521 tcaaaggctt tggaaaaggt cgatatggga aaatattcta atcatcaaat aggagaatta
     8581 tctggaggac aatttcaacg tgtactttta gcaagatgtc ttgctcaaaa tgcggatttc
     8641 atatttttag atgaaccatt tgtagggata gacttagtta gtgaacgaat aattatggat
     8701 acgttaaaag aattgaaaca tcagggaaaa acagtgctaa ttgtgcatca tgatttaagc
     8761 aaggtaaaga agtattttga taatattatt cttttgaatc gaaatctaat tgctcacgga
     8821 agtgtagaat ctgtatttaa tgaagagaat ttaaaaaaag cctatggaga tactatattt
     8881 att
//
LOCUS       DAXQKX010000085         8864 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.088, whole genome shotgun sequence.
ACCESSION   DAXQKX010000085 DAXQKX010000000
VERSION     DAXQKX010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8864
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.088"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..2269)
                     /gene="esp"
                     /locus_tag="ACF3MF_002501"
     CDS             complement(<1..2269)
                     /gene="esp"
                     /locus_tag="ACF3MF_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HFE3928409.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLVGVGLVLGTT
                     ELVQAQDEISPSTPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEEPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSASAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGKKVADLAIERRKDHENYGVGSITDNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSILDVYNKDFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDI"
     gene            complement(2886..3239)
                     /locus_tag="ACF3MF_002502"
     CDS             complement(2886..3239)
                     /locus_tag="ACF3MF_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928410.1"
                     /translation="MSCFVESERLSNGNNSVLNEYDKVVINKVKSLCEEARESISHIN
                     GSNFKQTLFNLIKLDAKISSYLFFLIHDEFMDYQKLDQLIERESWEDYYVGLTFSEKL
                     NNYKLIDYKYLSESN"
     gene            complement(3336..4541)
                     /locus_tag="ACF3MF_002503"
     CDS             complement(3336..4541)
                     /locus_tag="ACF3MF_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HFE3928411.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKDFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTGNLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
     gene            5235..5621
                     /locus_tag="ACF3MF_002504"
     CDS             5235..5621
                     /locus_tag="ACF3MF_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFE3928412.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFNKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            5719..5910
                     /locus_tag="ACF3MF_002505"
     CDS             5719..5910
                     /locus_tag="ACF3MF_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3928413.1"
                     /translation="MNTLKEDFILAKNGNEEAVVAILKRFSALVHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            6424..6756
                     /locus_tag="ACF3MF_002506"
     CDS             6424..6756
                     /locus_tag="ACF3MF_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFE3928414.1"
                     /translation="MKKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            6666..6869
                     /locus_tag="ACF3MF_002507"
     CDS             6666..6869
                     /locus_tag="ACF3MF_002507"
                     /inference="COORDINATES: protein motif:HMM:NF024673.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFE3928415.1"
                     /translation="MFYEHKDRYGSPGITQKLYDEGIEINKRVVAVLMREMNLCTRGF
                     HRRKSSHGREKTIKEMVKKMLNR"
     gene            6900..7046
                     /locus_tag="ACF3MF_002508"
     CDS             6900..7046
                     /locus_tag="ACF3MF_002508"
                     /inference="COORDINATES: protein motif:HMM:NF012870.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928416.1"
                     /translation="MTDITYIPCNDGRLYLSTYIDLATRILRYYMVDSHMKKEIVVRP
                     LQIY"
     gene            7053..7208
                     /locus_tag="ACF3MF_002509"
     CDS             7053..7208
                     /locus_tag="ACF3MF_002509"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HFE3928417.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLTDHHITHSMSQTGTPVDNAVIE
                     AFHRSIK"
     gene            7484..8824
                     /locus_tag="ACF3MF_002510"
     CDS             7484..8824
                     /locus_tag="ACF3MF_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFE3928418.1"
                     /translation="MSYSEFTKELLDILDLNLTFHEDAFRKERINDETCFVFDGTLTY
                     QPEECFHCHYQNKQTIIKWGWKKVSILLNDVSNYKTIVRINKQRFKCKHCGKTFLAED
                     SVSDRRCSIARRVKQAILELLSEPISMSLIARMKHISPTTVIRILRSLRPKTVSLNQP
                     LPEVVCFDEFKSVKNVSGAMSFVMMDGKTHQLIDIVENRQLNPLRDYFLRYPRKVREQ
                     VRLVVSDFYTPYRTLVKECFPNARIVADRFHISQHIGRAFTNHRIQVMKTFKKGDRRS
                     KHLKKYWRLLQKNAWELNGQHRYWRPSFRDHLTEAEIVDRLLYYDDSLKRGYEVYQVF
                     LSAIRRQDVPEFVALLKEDYKELPEHYQPVFTTFKKYRTEIKRALRVPYSNGPIECLN
                     NHIKVLKRIAYGFRNFQNYRERIFLYRGKYFKKTKNTTQLTKARTTTRLDKIAV"
BASE COUNT         2935 a         1630 c         1341 g         2958 t
ORIGIN      
        1 aaatatcttt acttacagtt actgctaaat cggtcgtgcc tacagaacca tcttggtaaa
       61 caattttaat aggaattgtt ccagtaatcg gctccgattc tcctacacct ttagctggag
      121 tgaatgtaac aataccagta tttgcatcaa cacttgcatt accgaagtcc ttattataga
      181 catctaaaat tgaaaaggca tctttagcta aaggaacatc tggtttatca aatgtaggtt
      241 ttccactttg aactgtcgtt tctggagttg ttgttatagg tacgtatgtt gcatcatttt
      301 ccatagcttg agaagctttt acagcaaact ctacatccac gtcgaaagtt cgatttccga
      361 tcttaacagt tacaatacct ttcgtactat cagtaacgtt agaagtatca ggctctgttt
      421 tccatgaata ctctgcatct tcaggtaagt ttttattatt ccgaattgat tctttagcat
      481 ctggtttaaa tccaactacc acggtttgtt tatcaaccgc ttttggtgat tccttaataa
      541 cggttgaacc ttcttctggt ttatcaaaac ctggagaaac gatttggatt tttaattcat
      601 ctttcgcgat taatttactt gaatctacac ccgtaaattc aaattctaca gtatctgaaa
      661 ttggagcccc atctttttca tttggagcga tagttttttc tgctaataca gtaccttctt
      721 tatcaacaag ttgggctttg tgacctgttc ccgctaactc gtggatgaat actttcccct
      781 taactgttgt gtcaacatca tatacttctt ctaattcagg tttcccgata tatggattcg
      841 tgtctccgct ctcttcttta tcgtcagggt ttccatcacc atcaatatct tgcaaataat
      901 aataacctgt tccataagtg ttctggatta attttttatt cgtatccgac aaccaagaat
      961 caaagatgaa atcttcacca aatggtttat tttcttcaac ttgtgctgtt gctttcatat
     1021 cttctaagat ttcatctaat ggcttagtca attgtaaaac atatcgaata acgactggac
     1081 gtggacttgc attagcaaaa tcaataagtt tggtaagatc attatcagta attgaaccta
     1141 caccataatt ttcatgatct ttgcgccgtt caattgctaa atcagccact tttttccctg
     1201 attcaaaaga aacatcatat gttactttgt cagcctgaac catgtgcatc tgtatacccg
     1261 ctacatatgg aactaatcgt tcatcaattt tgtaattagc ataccaaggc gtgccctttg
     1321 cggaagctga atatgagaaa ttataatttt tcgttaactt atgatctaag attatagctc
     1381 cattagcacc tgtggatcct gaaccatctt ttgtttgagt attaggttcc tcatattttg
     1441 cacttactga tccatgttta aactggtcag gattattttc agatacatct aagctattat
     1501 agaaatcatc tgaatctgtt aaaaagtagc ccgtactatc aatacctggt acaattttat
     1561 catcgtcttg atgacttacc aagtagattc gatacattaa acgatcggtc ttgagattgt
     1621 ctatgcctat ctctttaaaa atttcatcta agctcttttc aaacgtaatt accccattag
     1681 gagcagtttg tgtatcagtt gtttcagccc cagcaaataa tccatcactt gcacgaatat
     1741 aattgacctt ccaaatattt gtaggtctac ccagcgaatc attaattctt acaaaggtcc
     1801 gtctagaaga tccaattcct ttctttggat cgacctgaat tttttctaca tatttagcta
     1861 atcgttcatc taattgaaga cggatttccc agtttttagt tgatgctgca atattatgtt
     1921 ttccgtaaac ttcaaatcca attgtattgc cttttagtgt gtctccagtt agttcttgag
     1981 gactaaattg taaatccgaa aagttataat ttttcgtata accaggattc tcctgaaaag
     2041 tattccccga agctactttg tcacctactt gtacggagct tatcgctgtt tcaagtgggg
     2101 tgcttggaga aatttcatct tgtgcttgaa ctagttcagt tgttcccaag acaagaccaa
     2161 caccaaccaa aacagatgca accccaacac ttaatttttt gatactgtac ttcaatactc
     2221 gtttctttgt tttttctaga aatactctct tattattctt gctaaccatt attcaaatca
     2281 actcccttaa tagttatttt cttagtaaga ataaaagata aatctgatac gtattattca
     2341 cagaatagga atcttactaa acttatgtta actagtttac ttaaagaatt tcatgcacat
     2401 tacaacaaaa aaagtacatt tcttcatgtt tttttcggat atttgtgctt tttaaccatt
     2461 cagcagctga aaacatataa aaagatatgt atgtattctt tctgaaatta agttcatttc
     2521 tatgcgatga agcatgtttt caaaatatta ctctttctta gattaaactt cagagtattc
     2581 aaatagcgga ataaggagcc ttatcccgca ttactgaatg agactgtgac ataagtaaaa
     2641 aggtgacttc aaattccttc ttcggaattt gaaatcacct tctttataat tataaagtat
     2701 cggtttcaca gcattcctga atgattccta gaatcttaaa cgaatgattg gagttatcaa
     2761 cattttttca ctcgttttta gcgaaacaaa aaatgacatt tgtcacagcc tcattaaatt
     2821 attgattctt tttctttata attgaattgt ccatatttaa agtgtctagt actctacatg
     2881 aataattaat tgctttcact caaatactta taatctatta acttgtagtt gtttaacttt
     2941 tctgaaaaag ttagacccac gtaataatct tcccagcttt ctctttcaat taactgatcc
     3001 aatttttgat aatccataaa ttcatcatgt attaaaaaga ataaataact tgatatttta
     3061 gcatctagct taatcagatt aaataatgtt tgcttaaaat tgctaccatt aatatgactg
     3121 atagattctc tagcttcttc acataaactt tttactttat taattactac tttgtcatat
     3181 tcatttaaca cactattatt accattactt agacgctcag attctacgaa acaactcaaa
     3241 tcagaaattt cccaaaaaat tttttgttaa aatccaattt cctcaactcc tccaaactac
     3301 gtaaatgata tagtctcata ataaaataaa acctctcagc taatgttgtt gaaattatcc
     3361 actaaaccta attgatattg cttaggagat acacctgcgt actttttgaa tactctcgaa
     3421 aagtgtgaag aatctgaaaa tcctaaacct aaagaaactt cactgatagt atggtttgat
     3481 ttcaacatta ttttagccgt agaaattttt cgcttagaga tataattata aatcgtaata
     3541 tgcatttcat tcttaaagct ttctcttaat ttagtttcac ttacagaaaa ataattagct
     3601 atttccttta cagtaattct tttatagata tttaagccga tgaattgaac gacagaagaa
     3661 attaagggag aaagatgctc tatcttagtt tttccgattt ccttagtata ataaacaatc
     3721 ccagaatccc tcacttttaa gacctcaggt aacgatacag ctaattcgtt ttcttgtatc
     3781 aaagcatctc tactttgata cgcttctatt atatccattc ctaatgttat agacgtttgt
     3841 gctaactttt caaaaacaat gatagaataa tttttttcag accgaatcgt atctccacta
     3901 acacttggaa ttattccatt actcagatta aaaaccatgt tttctaaatt tcgaatatct
     3961 ccatttttaa catattccag tattttattt tcataaagaa acagatatat ttctggatcg
     4021 taattttgtg ataacagatt atctattttg atttgctcga tagttttact tagatttcct
     4081 gtatattcaa ttaacggttc atggaataga tcttctattt ttccagtaaa aaaataatga
     4141 actaaaatca gaatatctcg aatgtctcct aaagaataca aagtcaaatt ttgcaatgaa
     4201 ttatagagtc gttctctatc agccattgca acattcaaat tgttcatttt tagtttaaaa
     4261 aaatctttat caatattatt tgctctaaat ggaccaaata agtaatatct ggttttaaac
     4321 atgtatagaa gaaacatctc attaaaatca ccagtaaaga aatggaaatc tttagttttt
     4381 ttaatattat cagttagtaa ctttttataa tcataaaaaa aataagtagt tctatctgag
     4441 cgatactctt ttataatact gaattcggaa ttaaaaacca cgataggtaa ctttaaacaa
     4501 acatgaagag actttaataa gacttcttta tctgaaaaca cttttgtttc tctctttcct
     4561 ttctacatca ttaaatagta ttttatacgt tatctaaaat actattcctc tgtcaaaata
     4621 agctaactta cttcattata aaatatccac ttatcgcttt catgtatatt ccaccgtaaa
     4681 aagtacattt tatcaccgag aactcatcat ttttcatcat gatgaatact atttacatat
     4741 atctagttca aagacaataa ttattatgat ccgttattat ctaagcacta tacagataat
     4801 aggaattttt cgtttctaaa tactccaatt tgggaatcca ataaaaattt tcgttcaaat
     4861 acgtgtctat tcgaactctt ttctagttgt taattatgaa gggggaagaa ataaaaaata
     4921 caatctatac acgaataaga atattatcca aaaggaggtt ttagaaaaga tttattatac
     4981 gtaaaaagct caagacattt tcttagccat aaggacatgt ttgatattta agaagatata
     5041 tgaattttct tttctaagta taaagataac tatccattat caactaaaaa aacatttttg
     5101 aaaataaaca tcagcagtcc tatcaatgca tgtgagctta tagaagttat tcgcagcgca
     5161 gcataattgc attagcttct tttcgtgttt tttgcctctt ttccctttaa atcttaatgg
     5221 aggaggtgtg caatatgtca gataacgacg aacgcgtaaa tgcccagttg attcgattct
     5281 ttgaaaaggt cattttgaac accgctaata cttattataa aaaacaagaa gaaattcaaa
     5341 aacatgaaca acttgatcaa ctcccaccat atttgtttac taaagatact ataaaattta
     5401 aacaaccgat taatgtttta aatgtgactc tccttgttga agatataaaa ttagcaaaaa
     5461 tccttccttt gttgaaagaa cctgaacaaa tttttcttat cgaaaaattt atctttaata
     5521 aaactgataa agaaattgga aaggttctgg gtattacaag acagggtgcg acaaatttaa
     5581 aacatcgact ttacaaaaaa attcaaaaaa tgctggttta atatctgcat aataactaat
     5641 tttgtatgct tctttgctcg tcctcctcct tcccaaaaaa ataaatagat tataagttca
     5701 tgggaagaag gtaaatttat gaatacttta aaagaagatt tcattttagc aaagaatgga
     5761 aatgaagaag cagttgtggc cattctcaaa agatttagcg ctttggtcca taagcaatcc
     5821 tggagaactg gaaaatatga tcaagattgt tatcaagaat gtatgcttgc aatatatcta
     5881 gctatctcga aattcgaaat taaagaataa ctcaactaag ggagtctgtg acataagtaa
     5941 aaagatagtt tcaaatttcg aacaataaat ttgaagccat cttctttata attataaagt
     6001 atcgatttta cagcgttcta taatgattca tagaatctaa aacgaatgat tttaattatt
     6061 aacgtttttt aattcgtttt tagcttaaaa ataacttttg tcacagtctc actcctaaaa
     6121 ttactttatt tacgtacgaa gtgggcagga ggtcgaatcc agaactgggc catggtactt
     6181 caacgaggac ttctcctcta gaattgaaaa gcatgcgatt taccttccgt aacgacggta
     6241 gatttattca actatgtgtc caatcaaaat ttgtctgatt tcaaaaatag tcaagagaat
     6301 tttggttgtt aaaaactctt atctatcaac ttccacagtt tagttgacaa accctgatac
     6361 taagttgggc tatgatacac ttttcttgac tatcagttac gttaccggaa ggaatgaact
     6421 ctattgaaaa aaacatatga tcgtaaattt aaactaaaga tttcacagga tatccttgag
     6481 aaaaaagtaa ctaccaagaa aattgctgaa gaatacaata tctctcgtcc aacaatttcc
     6541 cgatgggttt cagaatatcg tcgatacggg aaaaatgctt ttgctggaca aggaaaaaga
     6601 ttacctgata aagcagattt ctacattctt gaacaggaaa ataaacgact aaaagaggaa
     6661 gacgagtgtt ctacgaacac aaagatcgat acggatctcc agggatcact caaaaacttt
     6721 acgatgaagg aatcgaaatc aataaacgtg ttgtagctgt tcttatgcgt gaaatgaatt
     6781 tatgcacaag aggatttcat cgacgcaaat cttctcatgg tagagaaaaa acaatcaaag
     6841 aaatggtaaa aaaaatgttg aatcgataat ttgaacagaa ccaaattgat gctgtttggg
     6901 tgacggatat tacttacatt ccatgtaatg acggtcgcct ctatttgtcc acctatattg
     6961 acttagcaac tcgtattcta cgttactata tggtggattc acacatgaaa aaagagattg
     7021 tcgtccgtcc attacaaatt tattaaggag aattgcctac ggtaattcat tccgatagag
     7081 gtagccagca tcggtctttt atttatcaag agctgttgac cgaccaccac atcacacatt
     7141 caatgagcca aactgggact cctgttgaca atgcagtaat tgaagcgttt catcgatcaa
     7201 tcaaatgaga attaatcgac tccaacaaat ataaaagtaa aatagagatg aaggtgttaa
     7261 tccaagatta tttagaagac tactacccaa acaaaagaat ccatacaaaa tttatgatga
     7321 ctccttgaca atttgaagcg aagaaaataa gggatctata atatctagtg ttggtgacgc
     7381 cttctgttgc caatactttt tcttttttct aataaacgca aacagacacc ttgaaatcct
     7441 ttagaataaa gtcgacgaaa accattcaaa ggagtgtttc aagatgtcct attcagagtt
     7501 taccaaagag ttactagata ttctagacct aaatcttacc tttcatgaag atgcctttcg
     7561 caaagagcgc attaatgacg aaacatgttt tgtttttgat ggcacattga cctatcaacc
     7621 agaggaatgc ttccattgcc actatcaaaa taagcaaacg atcattaaat ggggctggaa
     7681 aaaagtatcc atcttattga atgatgtcag taactacaag accattgtgc ggattaacaa
     7741 acagcgcttc aaatgtaaac actgtggaaa gactttttta gcagaagatt cagttagcga
     7801 tcgtcgctgc tccattgccc gcagagtcaa acaagccatt cttgagctat taagtgagcc
     7861 tatttctatg tctttgattg cacgtatgaa gcacatttct ccgaccactg tcattcgaat
     7921 acttcgcagc cttcggccta aaaccgtttc tttgaaccag ccgttaccag aagtggtgtg
     7981 tttcgatgaa ttcaaatcgg tgaaaaacgt ctcgggagcc atgagctttg tcatgatgga
     8041 cggcaagacc catcaactga ttgatattgt ggaaaatcgg caactcaatc ctttacgcga
     8101 ctatttcttg cgctacccta gaaaagtccg tgaacaagta cgtctagtgg tttcagattt
     8161 ctatacaccc tatcgcacat tggtgaaaga gtgttttccg aatgcccgaa tcgtcgccga
     8221 tcgctttcat attagccaac acatcggtcg ggcctttacc aaccaccgaa ttcaagtaat
     8281 gaagaccttt aaaaaagggg atcgtcggtc gaagcactta aagaaatact ggagactact
     8341 tcaaaagaat gcgtgggaat tgaatggtca gcatcgctac tggcgtccgt catttcgaga
     8401 tcatctgaca gaagcggaga tagtcgatcg gctattatat tatgatgact ccttaaagcg
     8461 aggctacgaa gtctaccagg tttttctttc cgctatcaga agacaagatg ttcctgaatt
     8521 cgtcgcgctc ctaaaagaag actacaagga gttgccagag cactatcaac cagtgttcac
     8581 gaccttcaag aaatatcgaa cagaaatcaa acgagcgttg cgagttccct attccaacgg
     8641 ccctatagaa tgtttgaaca accatatcaa agtactaaaa cgaattgcct atggctttag
     8701 aaactttcaa aactaccgag aacgaatctt tttatatcga ggaaaatatt tcaagaaaac
     8761 taagaacact acccaactga ctaaagccag aacaacaaca cggctagaca agatagctgt
     8821 ctagccgtgt gagtatctcg attattctat tgaatttctt cacc
//
LOCUS       DAXQKX010000086         8593 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.089, whole genome shotgun sequence.
ACCESSION   DAXQKX010000086 DAXQKX010000000
VERSION     DAXQKX010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8593
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.089"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(52..1518)
                     /locus_tag="ACF3MF_002511"
     CDS             complement(52..1518)
                     /locus_tag="ACF3MF_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HFE3928419.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
     gene            1905..2501
                     /locus_tag="ACF3MF_002512"
     CDS             1905..2501
                     /locus_tag="ACF3MF_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFE3928420.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
     gene            complement(2559..3041)
                     /locus_tag="ACF3MF_002513"
     CDS             complement(2559..3041)
                     /locus_tag="ACF3MF_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928421.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(3147..3344)
                     /locus_tag="ACF3MF_002514"
     CDS             complement(3147..3344)
                     /locus_tag="ACF3MF_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928422.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            3639..4397
                     /locus_tag="ACF3MF_002515"
     CDS             3639..4397
                     /locus_tag="ACF3MF_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HFE3928423.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            4457..4885
                     /locus_tag="ACF3MF_002516"
     CDS             4457..4885
                     /locus_tag="ACF3MF_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928424.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            4931..5003
                     /locus_tag="ACF3MF_002517"
     tRNA            4931..5003
                     /locus_tag="ACF3MF_002517"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4964..4966,aa:Gln,seq:ctg)
     gene            complement(5153..5524)
                     /locus_tag="ACF3MF_002518"
     CDS             complement(5153..5524)
                     /locus_tag="ACF3MF_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFE3928425.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            5739..5924
                     /locus_tag="ACF3MF_002519"
     CDS             5739..5924
                     /locus_tag="ACF3MF_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928426.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(6007..6195)
                     /locus_tag="ACF3MF_002520"
     CDS             complement(6007..6195)
                     /locus_tag="ACF3MF_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928427.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(6219..6482)
                     /locus_tag="ACF3MF_002521"
     CDS             complement(6219..6482)
                     /locus_tag="ACF3MF_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928428.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            6640..6897
                     /locus_tag="ACF3MF_002522"
     CDS             6640..6897
                     /locus_tag="ACF3MF_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HFE3928429.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            complement(6968..7159)
                     /locus_tag="ACF3MF_002523"
     CDS             complement(6968..7159)
                     /locus_tag="ACF3MF_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928430.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(7300..7620)
                     /locus_tag="ACF3MF_002524"
     CDS             complement(7300..7620)
                     /locus_tag="ACF3MF_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928431.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            complement(7643..8077)
                     /locus_tag="ACF3MF_002525"
     CDS             complement(7643..8077)
                     /locus_tag="ACF3MF_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFE3928432.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            8412..>8593
                     /locus_tag="ACF3MF_002526"
     CDS             8412..>8593
                     /locus_tag="ACF3MF_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFE3928433.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
BASE COUNT         2724 a         1695 c         1362 g         2812 t
ORIGIN      
        1 aaaaaacagg aactgctgca aataagcaat tcctgttttt atgttcattg attaatgaat
       61 agagcccatt agttttttga ttggttcttt cacagtaaat agcaagatac caccgacgat
      121 tgctactgca ccgataatac cgaagtaagc agattctgtt cccggtgtgt agaagcgtgc
      181 aatttgtgca ttgattgctt gtgaagaagc atcagctaag aaccaaatag cgattgtttg
      241 tgattcaaat gctcgtggtg ctaattttgt tgtcacagac aaaccaactg gtgaaagaca
      301 caattcagca ataaccacga tgaagaaact tcccaacaac cacaatggac ttacttttcc
      361 acttgtacca taaagcatac ccggcaacat caatagcaag tacgataatc ctgcaaataa
      421 aagtccaaga gagaatttca ctactgtaga tggttgacgt tcaccaagtt tcgtccacat
      481 cgttacgaat actggtgtca gaataaagat gaaaattgga ttcaatgatt gataccagct
      541 tgcttggatc gttacaccaa atagcgtaga ttgtgtacgt tcactagcaa ataaagctaa
      601 gatagatgaa ccttgttctt gtaatgacca gaaaatgatt gctgcaagga ataatgggat
      661 ataagcccat actcttggtt tttcttcagc agttacatct tttgaagtca gcattttgat
      721 aaagtaatac aacggtaaga taatccccaa tacactgatt gtattgacaa aaaagtcaat
      781 tgtcagatga ccagttagtt gtgccccgcc gaatactgca gcgataacaa caagtgcgat
      841 gatcaagtta cggatgaatc ctttacgttc ttcagttgtc aaaggattcg gcggtgttgt
      901 acccactccg tctaatgtct tgcgtccttg gatgatgtat tgtaataatc caaagaacat
      961 cccaatagca gctaaagaga accctaaatg atagttatat tcttgaccga ttgtaccaac
     1021 gattagtggt gctaataatg cccctaagtt gacacccatg taaaaaatcg aaaatcctgc
     1081 atctcttcgc aagtcagtct ttgaataaag atgtccgacc atgccagaaa catttggttt
     1141 caaaaaggcg gttccgataa taatcaatgc catcgaaaca aacaatgtac ttacaccaaa
     1201 tggtaaagcc aagacgatgt ggccaagcat aatgaaaact ccaccgaaga atacagtgcg
     1261 ttttgctcct aacactcggt cagataccca tccgccgacg atactagaca tgtagatcaa
     1321 agatccgtag atcgacatga tagctaatgc tgttgctcgt ggtaatccaa gtcccccgtt
     1381 ggcaactgta tcgtacatat aatagataag taatgcacgc ataccgtaat aactaaatcg
     1441 ttcccacatc tcagtgaaga acaaagttga caatcccttc ggctgcccga agaagccctt
     1501 gtcttgctgt ttttccataa tctatacccc aattctttaa attttcagaa aatattatac
     1561 atctttaccg aaaaatttaa ctaaaaaact tatttaagaa atataaacta attttctata
     1621 aaagcaagta atttttaatg gcaatatcat aaaaaaaaga agatagagat ttaataatta
     1681 tatatcagct gtttttttca aataagcaaa aattcctaaa acacaacaat gaaagcgata
     1741 actaagaaaa tccttacata acgatttttc ttattaaaat tgttttttga acttcgctta
     1801 ttttttgtga gcatatctgt ttacttactt tttgtaaggt gctatacttc atttcgtaat
     1861 caattaaaaa aatgcaaaac gcaaatcaaa ggagaaattt tattatgaca acttttactg
     1921 acactttgaa aaaccgccgt tcaatctatc atctaggacg taatgtttca ctttctaatg
     1981 aagaattaac aactttgatc aaagaagcaa ttaaagaaag cccaactgct ttcaatgctc
     2041 aatcaacacg cgcagttatc cttttcggag atgcacatga aaaactttgg gaaatcactg
     2101 aagaagcact tcgcccattg actccagcag aagctttccc aaatacacaa aacaaattag
     2161 ctggtttcaa aaatggttat ggtacagtat tattcttcaa agatactgac gtggtaaaag
     2221 gtctacaaga acaatttgaa ttatatgcag acaacttccc agattggtca gaacaatcaa
     2281 acggaatcgc aacagctaat acttgggtag cattagttga taaaggattg ggcgcaaact
     2341 tgcaacatta caacccagtt attgacgaag cagttgcaaa agaatggaat atcccttcaa
     2401 actggaaact acgttcgcaa ttagtattcg gttcaccaga aacaccggct ggggaaaaag
     2461 aatacatgaa cgatgccgat cgcttccgcg tatttggata attttatttg aaataaaaaa
     2521 cagaggttgt gacaaacatc ttgtcgcaac ctctgttttt attctggatc aatcataata
     2581 tcaatctctg cctcatcgtt taagcgttgg gacaaaaatg gaactaattc ttctaatgat
     2641 gcagaaaatt tcagcatcgg tcctcgccat ccgtttcgga aaaaattcat ttttacgatt
     2701 ttagaacctt ttggctgata taatacaatt ttattgatct cagaaaaagg aacacctttt
     2761 ttgtcaaagc tattcaaaac aagtccttct tctgtgattc ctctactgtc caacaaaaaa
     2821 ctaataaaaa tcattgctga caagatccct tttgccaatt catctgctgt aggatgactg
     2881 atgagtgtat accaaatgac tagtgacact aagaagggta tcaccaagta gacccatcga
     2941 tttcgcacag tccgataaat aatttctttt cgaaccagcc aaagaaataa aaacatcaca
     3001 acaacgaata aaaacaatag aaccgtaaag aatgttacca tgacaactcg cctcgctttt
     3061 tcttctccag aaaataggaa aagaatactg atttaccttc tcaaagaaat tggacttgca
     3121 gcacgccgca cgtccaattg ttttctttat tcaaatgtat catattttgc aacaaccatg
     3181 cttgcttttt catctaataa ttcttggtcc tctgcagcac attgggcaac tttgaccacg
     3241 gcgcagtttg tcatttttga tacaacttca ccaatgaccg tttttgtaaa accaattggt
     3301 ttgcatgcat attgttctcc taaattaatc atttcttccg tcatcaaaat cctcctaaac
     3361 tgctggaact tttctccaca ttaccactgc tatttctttg gagatttaac tcattgattt
     3421 ttatttacag ttaaaaatca accttacagg cattatagcg tactgttttc gttttcacaa
     3481 ttaaaacagc tgttgtattt agaagaattt ttttcaaaaa attaaaacat attccttaaa
     3541 aactaattat ttcctacata ttaaaatata atacttccat ttccaataaa aatacattta
     3601 taataggaaa gataaacagc tgaaaaggga gatttcaaat gaagaaaaaa acgttcaaaa
     3661 aactattgtt tctagggggc acagctgctc ttttattaag cggtacaagt tattacctac
     3721 atatccattc tccagaacat acaatgaaca ctgcacaaaa aagttcaaca caaaaaacga
     3781 aaaagacaaa agagaaagca gaagttttac tagatgttcc attagagagc cagtttgatt
     3841 ctccttcttt agaaaatggc tgtgaagtca cttcgctttc tatgctttta tctttttatg
     3901 gttatgaaac aactaaaaac cagttagctg agcaattgga ttacgtccct gttttcaatg
     3961 cagatgggac tcatggcgat cctaatgaag gatttgttgg tgatatcagt ggcggagact
     4021 gggctatggt cgtctatgtt cccccagttg cctcccttgc tcagcaaatc gtccaaacgg
     4081 attatcacac ttttccaaaa accgatgctc aactcgatga tatcaaaaaa gcactatcta
     4141 aaggaaatcc tgtctggact tctgtgacta tcaattttga agtcccagat gaaactgatt
     4201 ttatgacttg gaccacaaat aatggagaag taagagtcac tcctcttgtt catgcttgtg
     4261 tagtcactgg atatgacaaa gaaaatattt atgtcaacga tccctatggt gtaaaaaatc
     4321 gagcagtacc gatcaacgat ttttcggcga ttttcactgc aatgggtgga cagatgctaa
     4381 ctttggagaa aagctagtaa ttcaaacaaa aatcccttat actcaagata ccaaaccttt
     4441 gaagggagcg tagataatgg aaaaattcac acataaaaaa atggatccaa atgaaattcc
     4501 gattattttt gtccgtgact gcaagggaaa tgttcaaggt aaagtctcta ttaatgagtg
     4561 gaacgagcgt cgcagacctg ctaccctcaa tgaactggaa atcaaattgt atcgtcaatc
     4621 tcttgtttat tacgcagatc aagagtacga gaaagccacc gatttattga aatttctaat
     4681 tgctcgaaca gagtatactc gctttgaata tattgaacgt ttagcaaaca tctatcatat
     4741 tatgaatgaa cctgtcaaag aatatcagtt attggacacc gtcttgtcag tagcagaact
     4801 gattgccctt cctgctggat tagaaaagaa actagtacgc cgccttttac gagtaaagca
     4861 acaactatcc gatcaagaaa aataacttgc gtttttttag gaaagtgcta tgattatttt
     4921 gttgaataaa tgggatgtag ccaaactggt aaggcacttg actctgaatc aagcaattgt
     4981 aggttcgaac cctgccatcc caatttgatg tgcttgctga aaaaatgaac cccctgtaaa
     5041 agaacaatct ttttgcaggg ggattattgt attattttta ctacttgtat ttagtttaca
     5101 taattaaatt atgaataata aaatcgggcg tattcttaat acaaaaactg atttacccaa
     5161 taattgctaa tgctttctcc ggaacttttt ctctaggaac ttcctcatac gtttctatgt
     5221 gtgctccttt attgctaatt ttcaaataat gattttcttt taacacagaa agaccattaa
     5281 attcaaccgt tcgttctttc ccattggcat cagcagcttt ctgcacatac cttgctgtac
     5341 catattcatt tacttcctct ggtttttgtg tctttacata gacctctcct ttttcaacta
     5401 atggatttag ctgatcaagt ataccaggga tttctccata acttccttca gtataatatt
     5461 tcagtccaaa tagcaaaata ccactaatcg ccgccagtcc aatcaaatat ttaatcactt
     5521 tcatctttct acctccttgt tatatattca gtatatgggt cagttaaaga aattccatcc
     5581 gtcccaagtt ggagattttt ctcctacttt agaagcgaga atcgagtgtt tttttagtaa
     5641 aaatgatcgt tatttgatat tattgacgtg tggataaatc agtttttctc gttttgtcca
     5701 tgtaaaaaat catgttgata gcaaaggatg tgttcaaaat gaatcaagaa gaattatttc
     5761 aaaaagtcaa ggaaatgatt aagaacggca atttcgatgg cgcaaaacga tttatcgaag
     5821 aacataaaga acaattagga ccttataaag agaaagccca aaatctttta aaagatgtaa
     5881 atatcgacag tgtcaaaaac aaatttaaaa atctattcaa ataagtaaaa ctttcacttt
     5941 tgtaaaatca aaggaggaca atgctgctgc atcgtcctcc tttggttctt ttctgaatac
     6001 ttcatactaa aataaacgtg tcggatcgta atgataagtc acattgccgt tcagtgaggc
     6061 ttttcccacc acatatttac gattctccaa cttcagccac gcttctcgaa aagccattaa
     6121 ttcttctctt tttacatcaa tcttttcgat ttttccatcg atcaaatctt gaataagttg
     6181 ttcatatgga ttcatttttt tcctccatct gctgtcaatc aataagttgt aaaaataggt
     6241 tcatatgctt ttttggtatc tagatcttct ctgactttga ctgtcgtata aataattttt
     6301 tctactggga tactataata acttccttca ccattattga atcggtgaac gtctttcttt
     6361 gctaaaatac catttatttt attcgtcagt acacgttgtt cgacactgtt acttacaaca
     6421 tagtaaatca cccgaatatt attgatcaaa tgcaaatcga tttctaacac tacatgatcc
     6481 atgaaaatcc cactccttct ttcactttga ttatagcaag tttctcctct aatttcaaaa
     6541 tcgatacaga ttttaccgga taaatccaca aaactgcttg cgccatttcg cacaaagtgt
     6601 tattttgtat catggacttt atttatcgga ggcaatagta tgatcgcgat cggtcaattt
     6661 gttttttata ttcctttttt tattatgata agcattcttt tctattacat aaaatggaca
     6721 aaaaagaagt tttcagtttt actggcctct ttacctgctg tatattttac ttatcaaatt
     6781 ttttctttta ggcattggga aacaacgtct gtattaataa cacacatcat cgaattgacg
     6841 ctttcagtaa tttttcttat tatttggatc tattttttat ataagaatca gaattgaatc
     6901 cctcgcatgt ttaaaaagaa aacgattaaa gatgcagcaa atttctgccg atctttaatc
     6961 gttttttcta ttctgttata ccaaaaaaat gtttgaatcg gtgaaggatc gttccttgtt
     7021 ttaattctat aaattcttgt gcgatcgggt acttttcttc caaattttct ttgttctttt
     7081 cgatcaggct tttcgcttct tcatattttt tatctgcaca tagtgctttt acttcctgta
     7141 atacttttcc tgcttccatt tgcctcaccc tcttgccatt ttattgcttt aagttttatt
     7201 taagttatac gcattattct agtttcatcc caaataacct tttttcattt ttactcctcg
     7261 aactaatcag ttttctaaag gctgattggt tcgtcttttt tatttttcct ccatttcatt
     7321 ctgctcttct gttaatttat ctaatgcttt gattgatgct gcggctcttg cataatcata
     7381 gctgtataat tccataaatt tatcaggcag aacaaaccac gctggatgat aaccgttagc
     7441 tgtgacaggg aatcctttat cttgttggtt atctccatcc catctcagag caacaccttt
     7501 ttttcctttc cactttacta aagcgatcga gtatcccttc tttgtttgtg tgccgtcttc
     7561 aataattgct aaaatttcta ttttttcttt tggcgcacgg acttcttgag gacgaaccat
     7621 tttctattcc tcccttatct cattacttca cgaccaacac actgcaaggg gcatgtgata
     7681 cgacataaga agcggtcgat ccaactaatg cttgttgtat agcacctttt cctgtcgctc
     7741 ccataacgat caaatcaata ttttcttgtc cagggatgac attggcaatc aaatttcttg
     7801 gatctccagt ttcaactatt gcgtggatct cagcaatgcc gtactctttg gcatcattga
     7861 tttttttcag catggctact tctgttcttt gtttttcatc tgcatagatt tttgaaaagg
     7921 cataggcact atgggtcagc tcaactttgt tgatgattga cacgataaat aagtgggctt
     7981 cattgtcctt tgctaagtca agggcttcag cgaacgcttt gatcgattgt cttgatccgt
     8041 caactgctac catgatgttc tggtatcttt tactcattgg aaccgcctcc tttttctttt
     8101 attgtaacat ctcaagcaaa aatacaaaaa atatacgcaa tatgtaaata aaatgatgaa
     8161 caaaagcaat ttctttcaag ttatttatac atttcttttc tcatcagaac acctgttcta
     8221 atcccattat ttctgcatta tgtgaaattc ctcatcattt ttcacatcga gcgaacatca
     8281 ttctgttaca aaaaacgtgg atttgtcata aattgtcatg cttcttttac ctatgaaata
     8341 ttttcacgtg ttaaagtatt cctcgttgaa cacaacaaat aaaacttttt aacgaataaa
     8401 ggagattttt catgacatca cttaaaactt tactttttgg aacaactttg gctgccggcg
     8461 ctgcattctt catgggaacg actgctcatg cggacgaagc ttataccgtt caatcaggtg
     8521 atactctatc aacgatttct caaaaatacg ttggtgataa ctccttgatc aatgccattg
     8581 cagaatcaaa ttc
//
LOCUS       DAXQKX010000087         8444 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.090, whole genome shotgun sequence.
ACCESSION   DAXQKX010000087 DAXQKX010000000
VERSION     DAXQKX010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8444
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.090"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            382..570
                     /locus_tag="ACF3MF_002527"
     CDS             382..570
                     /locus_tag="ACF3MF_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HFE3928434.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            648..1661
                     /locus_tag="ACF3MF_002528"
     CDS             648..1661
                     /locus_tag="ACF3MF_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFE3928435.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(1728..2762)
                     /locus_tag="ACF3MF_002529"
     CDS             complement(1728..2762)
                     /locus_tag="ACF3MF_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFE3928436.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            2877..5102
                     /locus_tag="ACF3MF_002530"
     CDS             2877..5102
                     /locus_tag="ACF3MF_002530"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HFE3928437.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            5120..7003
                     /locus_tag="ACF3MF_002531"
     CDS             5120..7003
                     /locus_tag="ACF3MF_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HFE3928438.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            6984..7958
                     /locus_tag="ACF3MF_002532"
     CDS             6984..7958
                     /locus_tag="ACF3MF_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HFE3928439.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
BASE COUNT         2729 a         1523 c         1768 g         2424 t
ORIGIN      
        1 gttagtctac attattttgg cgatttgcca ataaggactg ttgagttgtg caaaatcaaa
       61 tctgggtcag aatgaacgtc attctgtctc agatttttcg ttatttcaat ttgattaact
      121 gattgatcaa aaagattttt attttcatat tctcaaatga ttcaacacta aatatacatg
      181 tttgacgcgg aaattattat tcgattttgg cggcatcagg ggggatgacg acgtagcaga
      241 cccattattt tactcaagaa aatgtccgtg cctattattt agaatacgat agtgaacgtg
      301 ctgggagttt tgttctttta gagaaagtct ctgaagataa attagttgtc ttagattttg
      361 actgtaacga aaaatggcga aatggaagag caccagcaag tgattgaccg gatctacgaa
      421 gcgacacgat atctgccttt ggatcgtttg tgcttaagtc ctcaatgtgg atttgcttca
      481 acagaagaag aaaatgtttt gtttgaggaa caatggaaaa aatttctttt gtcaaaagca
      541 ttgcagaaga agtttgggga aaatcattaa atcatctagg agagcttgat aggaaataac
      601 actatggtat aatcagaatg cttaatacta actactgagg gagccttatg aaaaagaaaa
      661 ttcttaaatt tatcggatgg ttcttcggaa tcattcttgg gatcgcgttt gcaatctttc
      721 ttgccttcca gctttccccc agacctggag cattcttgat caaccatatg ttttcaaata
      781 ctgttcaaat cactgataaa aaaacgttcg atcaagcaga aaaaaacgtg gcgaaaaaaa
      841 cagatttgac gtatgagtcc aagtataaag agaatactta tgacatctac tatccaaaaa
      901 acagcaaggg gcctgttcct gttctatttt gggtacatgg tggaggattc gtcggcggag
      961 ataaatcggg tgtcaaagaa tttgcgacaa aattagtttc agacgccaac atcgcagtgg
     1021 ttgcgatgaa ttatgaatta gcgcctgatt cagaataccc taatcaagtt cttcaagtga
     1081 atgaactgat caaagattta ttagctgaag aaaaagacga caaattgcta gacatggaac
     1141 aattattttt tggtggagat agtgcaggtt cacaaatcgc attgcaatat gcagctatac
     1201 aaacgaatga tgcgtatgct aaacaaatga aaatcaaaca gctacttcca aaagatagtc
     1261 tgaaaggaac catttcttat tgcggacctg ttgatttgaa gctaacagca cagcagcatt
     1321 cggatgatcg atttatgaag tttttcgtca aaaccgttgc gtggtcgttg attggaacaa
     1381 aagattggaa aacgagtgag caattgaaag aagctagtgt ggctgaccat gtttctaagg
     1441 aatttccgcc aacgtatata actgacggaa atgcatactc attccaggag caaggtcaag
     1501 cattagaaaa tcggttgaca gaattaaagg tacccgtgca atccttgttt tatacagata
     1561 caaaaaaaga gattacccat gaataccaat ttgattacac gctaaaagaa tcgcaaaatt
     1621 gttaccagca gacattggat tttgtgaata agtataagta agaggttgtg aaaaagccgt
     1681 ttcgttttga gtatgaagaa acgaagcggc ttttcacaac ctctctttca ataccttttt
     1741 gttcttggga taaaactttc cctaacaatc aatcgtgcag gataagtcaa aatgattggt
     1801 tcgtcccgta taccgtcaat tcgctccaat gccattcgaa cagctgcttg cccaattgat
     1861 ttcgcattga tttgaacact ggtcaagcca ggggagaggt ttgcgattgt ctcgatatta
     1921 tcaaagcttg ctacaacaat ctcttctcca atttggatat ttttttgttt caatgcccga
     1981 tagacaccaa ttgccattgg atcgctcccg acaagaatgg cagtaggaag aggggattca
     2041 ttttctaata gattagtcgc aagtacctca ccttgttttt ctgtccagcc acctagatga
     2101 taagacatat atttttctaa gtgatgatcg atcataaaat gctgataggc acgcatcctc
     2161 ttttcattta tagaaatctg cttcccaccg aattcatcca tatcgacttt atatcccccg
     2221 atataggcta ttcttttatg accattttct aagaacaatt ccagtacggt tttagtcatc
     2281 cgttcaagat ctgcatacac catatcgacc tcttgctgga tgtcagggtt atccacgacg
     2341 actatttgca tgttttgttt taacaaggcg gtaatcgatt ctttcgtaac agtcccaaca
     2401 acgatcaccg cacctaactg atctagatct tcccattgtt taggattatc agatagatta
     2461 tagattcgat tcatccctaa atgcagacgt cgagcttctt cttccatccc tactcgcaaa
     2521 tgtttgtaat agatatcctg ttcttcgctc gctttgccga tcgtagagat cacaccaatc
     2581 gaaggcattc tctttttgat atatttacga gtactgatgt cataatccaa cgcagcagct
     2641 gcctctacta tccgttgccg agtagtctga gccacatgga tcgtctgatc gttattcaac
     2701 acacgggaaa ctgtagcagg agagacattt gcctttcgtg cgacatctct aattccaacc
     2761 atttttacac actcctcaaa aaaataaaaa atttttattg acaaaattgt ttagtaaaca
     2821 gtatacagga attataaaaa aaagtaaacg gtttccgttt tgttgggagt gaaatgatgg
     2881 atattacgca tagaaaaaca gataaaaatt tcatcttatt tgatgaaaag agccgagtct
     2941 tccatttacg aaatacattt ctttcttatc tgataaagat agaagaaagc aatgtattgg
     3001 cgcatattta ttttggcaaa ccagtcaagc agtacaaaga caataaaaat tatccccgaa
     3061 gagatcgtgg attttcagga aatgttccct taaatcctga ccggtctctg tcgaaagata
     3121 cactaccgca agaatactct tctcatggca gcatggactt tcgaacgccc gcatcgatca
     3181 ttcagcgcaa gaatggatca gacttactgg atctgagata tgacagccat tatattacag
     3241 atgggaagcc agagatcgaa ggcttgcctc aaacttatgt gatggacaag tcagaggcac
     3301 aaacgttggt gatttcactt aaggatagag aaacagcgat ttatttcgat ttgttctata
     3361 ccatatttac tgatagagca gtgatcacac gatctgtaaa gataagaaat gaaaccggag
     3421 aaacaatcaa actagaaaaa gcggctagtt tccagctaga ctttgcccat actaggcgat
     3481 ttgatgaagt cattgctttg ccaggagcac atgtcaatga aagacagatt tcacggcaat
     3541 ctgttttatc tggaacaaaa gtatttgaaa gccgtcgagg aacgagcagt caccatatga
     3601 ataactttat tgctttagtt catcatcata cgacagaaaa tactggagaa gcgatcggac
     3661 ttcaatttgt ttattccggc aaccattctt tcgaacttga aaaagatcag atcaatcaat
     3721 tgagagtcgt cggtgggatc aacagccatc gtttttcgtg ggaattgaat gcaggccagt
     3781 cttttcaaac acctgaaatg atcctttctt actcaagtca gggattgaac aaaatgagtc
     3841 agatccacca tgagttgcta cgtgaaagaa tcgcaagagg tcgtcatcaa tttgctgaac
     3901 ggccgattct ggtcaataac tgggaagcca cttactttga cttcaatagt gaaaaaatca
     3961 aggcgatcat tgatgaagca aaggagctag gcatcgaaat gttcgtatta gatgatggct
     4021 ggtttggaaa aagagatgcg gacaattctt cattaggaga ctggttcgag tatgaaggca
     4081 agttgacaaa tggattacgt gaaatagcag attatgctca tagcaaagga ttgaaatttg
     4141 gtttatggtt tgaacctgaa atgatctcgg ttgattctga actgtatcga acacatcctg
     4201 attttcttat gcaggagcca ggtagaatgc cttctgcttc cagatcacaa catgtactgg
     4261 attttacaag gttagatgtt cggcagacga ttgagaaaca aatgagaaag attttagata
     4321 cgattcctct tgactacatc aaatgggata tgaaccgttc gctttcagat gtctattcga
     4381 ttacccttga cccacagaga caaggagaag tagcgcatcg ttatatgctc gggctttatg
     4441 aactacttga acatttgaca actgattatc cggaaatctt atgggaaggc tgttctggtg
     4501 gaggtggacg gtttgatgcc gggtttattt attatatgcc gcagtcatgg acaagtgata
     4561 acacggatgc agtggagcgt atgaaaatcc aatatggaac aagccttgct tatccgattt
     4621 cgtccatcac agctcatgta tcagctgtac caaatcatca gaccgacaga tctacttcgt
     4681 tgaaaacaag aggagaaaca gctatgagcg ctgtttttgg ttatgaactg gatttgacaa
     4741 agctgtctcc tgaagaaaaa aagcaagtaa aagaccaaat tatatcctat caaacgattc
     4801 gtccggtgat ccagtatggc cattattatc gtttggcgag tccttttgaa gaaaatattg
     4861 ccgcatggat gtttgtgtct cctaaacaag atgaagctat tgtgttttta gggaggatac
     4921 tagcttcagc tcaaccagcg ttccatgaag tatatctgat ggggttagat gatgaggcac
     4981 tttatcagga acagacctcg aagcggatat tttcgggggc cgaattgatg acagttggac
     5041 tttacttccc cgattttcaa ggtgatttcc aaacagaact gcttcatttc aaaaagttat
     5101 gagagagaag gaaaaaagta tgaaagcaaa tataaaatgg ttagatgatc cacaagtttt
     5161 tagagtgaac caatcaaatg cacatagcga tcatgtttgt tatgcaacaa gggaagaagt
     5221 agaaaccaca tcctccctta aacagtcttt aaatggatca tggcgttttt gttattcgcc
     5281 aaatccttcg gtacgaccaa aaacatttta taaaaaagat tttgatgcct gttcttttga
     5341 tgaaatcact gttcctagtc atattgaatt agcaaattat gacaagatcc attacatcaa
     5401 tacgatgtat ccgtgggagg gacatgtatt tcgccgtccc cctttcacga caagccctga
     5461 gaaagaggcg gaagggatct tttcagctgc taaagacaat ccggttggtt cgtatttgac
     5521 gacttttcga ttagaagaag gtctaaaggg aaaacaaatc tcgattcatt ttgctggtgt
     5581 agaacaagca atgtttattt ggttgaatgg tcattttatc gggtatgccg aagattcgtt
     5641 cactccgtct gaatttgatt taacacctta tttggaagaa gaaaatattc tagctgtgga
     5701 ggtttacaaa agaagtacag ctgcattctt ggaagatcag gactttttcc gattttttgg
     5761 gatcttcaga gatgtcttct tagttgctcg aggacaaaac catttagaag atctttggat
     5821 caaacctcgc ttagatgaca aatgtcaaaa tggcaaactt gaagtagatt tgtcttttga
     5881 gcaagtagcc aaaaacagtc agctgaatgt agcgatacta gatcctgatg ggaaggaaat
     5941 ctatcaacag caatatccgt taaaagagca aatgacgatt cgcatcgatg gatttgaaaa
     6001 tgtggcactg tgggggcatt ttcagcccaa tttatataag cttgaattgg agacgataga
     6061 cgaagaaaaa agagtaacgg agtatattga ctattccttc ggttttcgta aaatcgaaat
     6121 caaagataaa atcatctact tcaatggaaa acggatgatt atcaacgggg taaatcgaca
     6181 tgagtggcat ccgaaaaaag gacgcgccat cactatagaa gatatggaaa aagatttggc
     6241 tatcataaaa aatgcaaaga tcaacggcgt acggacatct cattacccca accagatcac
     6301 ttggtattat ttatgcgacc aagcaggaat ccatgtgatg gcggaaacga acctcgaatc
     6361 ccatggctca tggcagaaaa tgggcgcatt tgagccttct tacaacgtac caggtgcagt
     6421 acctcagtgg caggcggctg ttcttgatcg agcaaaaacg aatttcgaaa cattaaaaaa
     6481 ccatccaagt attctttttt ggtctcttgg aaatgaatct tatgcggaag aaaacattcg
     6541 acaaatgaac gattacttca aaaaagtaga ccccgatcga cttgtccatt atgaagggaa
     6601 ttttccaaat ccagcattcg aagattcgat ttcagatgta aaaagctgca tgtatgcgcc
     6661 accagaagag atcattgact accttgaaaa taaagcggaa aaaccgttca tcttatgtga
     6721 atatatgcat gacatgggga attcgttagg tggaatggat tcttacatga cgttgcttga
     6781 tcgttatgaa atgtaccaag gaggctatat atgggatttt aaagatcagg cgatccaagt
     6841 gactgatcca atcacaggca gagaagtgat gcgctatggc ggtgactttg acgataaacc
     6901 aagtgactat gaattctcag ggaatgggat cgtttttgca gatggacaag aaaaacccgc
     6961 catgcaggag gtaagatatt attatgaaaa atacagtaaa taaaagtcat atggatacgg
     7021 aaaaagttgc aatcgtcttc ggcgactgta cattaggtgt caaatcgggg aatacgcatt
     7081 atattttttc ttatacaaga ggcggactgg aatcgctcaa taaaaacgga aaagaatggc
     7141 tataccggga aacacttcca gttttttggc gagcaacgac cgataatgac agaggtagcg
     7201 gatttggatt taaatccggt atgtggttag gagccggatt gtatccaaaa gtcaaagaaa
     7261 tagaagtact ggtggacaat aaaaagatcg atttgccgat tgctccagta aataatcaat
     7321 attcaagtaa tgaatacgct gaaacggttg aaatcatttt tacactggaa atcaacacag
     7381 taccaaaaac ccaagtgaca atttcctacc aaatcgctgg agagggtaaa atgcttgtca
     7441 atatgcatta ttatggacaa aaaggattac cggaattacc cgcattgggt ttaaggttca
     7501 ttatgccaac gaaagcaaaa ttttttgagt atgaaggcct atcaggggaa acatatccgg
     7561 atcggatggc tggtggtgtc gaaggtattt ataaagtggc aggactcccc gtttccccat
     7621 accttgttcc ccaagaatgc ggcatgcata tggaaacgaa atgggtagaa ctaacaagaa
     7681 atcaaacgtt ggataatacg gataaagatc aagaagattt ttcgttgcga tttgaacagc
     7741 aggatacgcc atttgctttt tccgctttac cattcaaagc agaagaactg gaacaggcaa
     7801 cacatataga agaactaccg ccagaaagac gaacggttct tacgattttt gcaaaagtaa
     7861 gaggagtcgg gggtatcaat agctggggag cggatgttga gtcaccttac cgaatcagca
     7921 gcgaagagga ccatgaaatc ggctttatta ttcagtagca atctttagat tattatttga
     7981 aaaacggagt ttacaagaca aagctgcttt attctatatg tcatgaacaa gagagtaaaa
     8041 aagttctcag atacttttgt tcatgactat tttcttcaat aaaaccaatt gttatttttc
     8101 tgaaaaacaa agttaactat cagaaaatta aaaaaagttt cataaaaatg attgacagtc
     8161 gattttttta tgtctatact aggtacaatt cttacatcag tttggagcga ttttttatga
     8221 aatctagaaa acttacaaaa ctgaatacgt attactttag ctattttaga taggtttgta
     8281 ttcatgactt cgtgggtaca aacaaaccag gtttgtatct atgatggcta aagattttta
     8341 aacacgactt acagccacgt agagaaattc atctatagtg gctattttat atttttgcag
     8401 cgctttttaa ggctcgttga agatgttcac tgtagaggca attt
//
LOCUS       DAXQKX010000088         8251 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.091, whole genome shotgun sequence.
ACCESSION   DAXQKX010000088 DAXQKX010000000
VERSION     DAXQKX010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8251
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.091"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..197
                     /locus_tag="ACF3MF_002533"
     CDS             <1..197
                     /locus_tag="ACF3MF_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928440.1"
                     /translation="WFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLIIAIIAVGLV
                     FNAAGVKDILLELFNRIIGA"
     gene            314..811
                     /locus_tag="ACF3MF_002534"
     CDS             314..811
                     /locus_tag="ACF3MF_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HFE3928441.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSISELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMSDVARYYIEETGALGEVPASLQNYIDYESYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            898..1290
                     /locus_tag="ACF3MF_002535"
     CDS             898..1290
                     /locus_tag="ACF3MF_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFE3928442.1"
                     /translation="MKKIRSYTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAV
                     MILGNLPPLSMIEGAFLKYFGIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRRKLTY
                     AGKKVTLGRNQPQEAITAVRSEFYGISN"
     gene            1274..3721
                     /locus_tag="ACF3MF_002536"
     CDS             1274..3721
                     /locus_tag="ACF3MF_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFE3928443.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSILSAQERSKNEVTGKLKTVAYDKIDQQTDALISM
                     IGENQVDYRFFIGFKLLLNDQEFSMKSLTVEAKNAFTDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYPLSKKKLEH
                     ETLIKTYDLIKPTRCLVEEKQRYLKIQQEDETAYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVNLTSDEKNKGLLDPYVIMKNTKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSDGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            3724..5907
                     /locus_tag="ACF3MF_002537"
     CDS             3724..5907
                     /locus_tag="ACF3MF_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HFE3928444.1"
                     /translation="MKPSILNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVTPSGLSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHALMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNMTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRM
                     MRKPRMLMHAHMHRLQRKLGRSVTALGAGSAIASATGKKGQSGSGSSASTQADHSRPN
                     GQEKSTLGKRIGQTIGTVADTKDRMVDTAGNLKEQVKDLPTNARYAVYQGKSKVTDNV
                     HDLTRSISQTKADKASGRKKQQEQRRKTIAERRSEMEQVKQKKQPASSVHERPATKQE
                     QSHDGQTSRQTTVQASYRESQQAKQERPTVKSDSSSLKTERQSNTVQERTVQKPVTST
                     APTDRASQRSITKERQSTVQRVPLQNTKSRPPIKTATIKKGSKKP"
     gene            5904..6905
                     /locus_tag="ACF3MF_002538"
     CDS             5904..6905
                     /locus_tag="ACF3MF_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HFE3928445.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDGGFSNIHYGGV
                     DVSAEVLAHKPMVEKVAKEYGIEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLGVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGDEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKFEGWKYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTRHIPLLEAKA
                     GDLVFFHSTYNAGSYITHIGIYLGDNRMFHAGDPIGYADLTSSYWQQHLVGAGRIKQ"
     gene            6920..7834
                     /locus_tag="ACF3MF_002539"
     CDS             6920..7834
                     /locus_tag="ACF3MF_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFE3928446.1"
                     /translation="MMKFGKNQNTEKQTPKEKKPRVYKVNPRKKVVIVLWVLLGLSFS
                     FAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWELNDKSIDNRIEN
                     LKAYLTEELQALNVDTVRKDIPVSSSVKGFQIWTVEADGDNQFDVTYSVDQLITEGEN
                     TKTVHSAYIVSVYVDSTGNMVLIKNPTITSIPKKSDYKPKAIESEGTVDSITTNEINE
                     FLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIYNRKDNQVTVSLTVEY
                     IDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            8148..8195
                     /locus_tag="ACF3MF_002540"
                     /pseudo
     CDS             8148..8195
                     /locus_tag="ACF3MF_002540"
                     /inference="COORDINATES: protein motif:HMM:NF011335.0"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         2569 a         1568 c         1754 g         2360 t
ORIGIN      
        1 actggtttct atcaaacgct caatcactgg tgcttttagc aatcgttgtg attggcttgt
       61 atcttggctt caagcgtgag tttagcaaac tgattggctt tttaattatt gcgattattg
      121 cggttggctt agtcttcaac gctgctggag taaaagacat tttactagag ctattcaatc
      181 gcattattgg tgcttaaata aaaccgttct tttgtggaat ataagtggtt ttcttatgtt
      241 ccgcaaagga atggtacacc aaacgaagtg cggtagggat ttttgaatct ctacaaagaa
      301 aggacgtgaa tatatggacg atatgcaagt ctatattgcg aatttaggca aatacaatga
      361 gggcgaattg gtcggtgcgt ggtttacctt tcccattgac tttgaggaag tcaaagagaa
      421 aatcggcttg aatgatgaat atgaggaata cgccattcat gattacgagt taccctttac
      481 ggttgacgaa tacacttcta ttagcgaact caatcgccta tgggaaatgg tatcggagtt
      541 gccagaagaa ctacaatcgg agctatctgc tctgctcact catttttcaa gtattgaaga
      601 actaagcgaa catcaagaag atattatcat tcattccgat tgtgatgata tgtctgacgt
      661 ggcacgctac tacattgaag aaacgggtgc tttaggcgaa gtgccagcca gtcttcaaaa
      721 ctatattgat tatgaatcct atggtcggga tttagacctt tcgggaacgt ttatctcaac
      781 caatcacggg atttttgaaa tcgtctatta aatctgtcgg tacattctta ctggcagatt
      841 ttcttgttta cggggtagtc aaaagactat ccccattttt atgaaaggat tgattacatg
      901 aagaaaatac gaagctatac cagtatctgg tctgttgaga aagtgttgta ctccatcaat
      961 gactttagac ttccgtttcc cataaccttt acgcaaatga catggtttgt cgtgtcactc
     1021 tttgcagtta tgatacttgg caacttgccc cctctttcta tgatagaggg agcatttctc
     1081 aaatactttg ggattcctgt ggctttcaca tggtttatgt ctacaaaaac ctttgatggt
     1141 aaaaagcctt atggattttt gaagtctgtc attgcttatg cactgcgacg aaagctgacc
     1201 tatgcaggaa aaaaagtaac gcttggcaga aaccagccac aagaagccat tacagcagtt
     1261 aggagtgaat tttatggcat atccaattaa atatattgaa aacaatctgg tctggaataa
     1321 agatggggaa tgttacgctt actatgagct tgttccctac aattactcat ttctaagtcc
     1381 ggaacagaaa atacaagtac atgattcttt cagacagctt atcgcacaaa atcgtgatgg
     1441 caagattcat gctttacaaa tcagtacaga atccagcata ctttctgcac aagaacgttc
     1501 caaaaatgaa gtcactggaa agctcaaaac ggttgcctat gacaaaatcg accaacagac
     1561 agacgcttta atatccatga ttggcgaaaa tcaagtggac taccgtttct ttatcggttt
     1621 taagttgctt ctcaacgatc aggagttttc tatgaaaagt cttaccgttg aagcaaaaaa
     1681 tgcttttact gattttgtct atgatgtgaa ccataagctg atgggcgatt ttgttagtat
     1741 gagtaatgat gaaatcctgc gttttcagaa gatggaaaag cttttagaaa ataaaatctc
     1801 ccgtcgtttc aaaatccgaa gattagataa ggatgacttc ggctatctga ttgaacacct
     1861 ttacggacag acaggcactg cctatgaaga gtatgagtat cctctatcaa agaaaaagct
     1921 ggaacatgaa acactgatta aaacctatga cctcattaag cctactcgct gtctggtgga
     1981 agaaaaacag cgatatttga aaatccagca ggaagacgaa accgcctatg tagcttactt
     2041 taccatcaac agtattgtcg gcgaactgga cttcccgtcc tctgaaatct tctactacca
     2101 gcaacagcaa tttacctttc cgattgatac gtcaatgaat gtggaaattg tagcgaatcg
     2161 taaagcccta tctactgtcc gcaataaaaa gaaagaactg aaagacttgg ataaccacgc
     2221 ttggcaaagt gataatgaaa ccagctctaa tgtggcggaa gctctggaaa gtgtgaacga
     2281 gctggaaacc aatttagacc aaagcaagga atctatgtat aagctgtcct atgttgtaag
     2341 ggtatcagca aatgaccttg acgaacttaa acgtcgttgt aatgaagtga aagatttcta
     2401 tgatgatttg agcgtgaaac tggtacgacc ttttggggat atgctgggct tacatgaaga
     2461 atttttacct gccagcaaaa gatatatgaa tgactatatt caatacgtga cctctgattt
     2521 cctcgctggt ttaggttttg gtgctactca aatgctgggt gaaaatgagg ggatttatgt
     2581 tggctacagc ttagatactg gacgcaatgt ctatctgaaa cctgctcttg ccagtcaagg
     2641 ggttaagggt tcagtaacca atgcgttagc gtctgccttt gtcggttcgc tgggtggtgg
     2701 taaatccttt gcgaataacc ttatcgtcta ttatgcagtg ctttatgggg cacaagcagt
     2761 gattgtagac ccaaaagcag aacgtggcag atggaaagaa accttgccag agatttccca
     2821 tgaaatcaat atcgtcaatc tgacttctga tgagaaaaac aaaggcttac ttgaccctta
     2881 tgtaattatg aaaaatacca aagattctga atcactggct attgatattt tgacattcct
     2941 tacggggatt tcctctcgtg atggggaacg cttcccaatc cttagaaaag ccattcgtgc
     3001 agtaaccaat agtgaagtgc gagggttgat gaaagtgatt gaagaattac gggttgagaa
     3061 tacgccacta agtaccagca tagccgacca tatcgaaagt tttacagact atgactttgc
     3121 ccatctgctt tttagtgatg gttatgtaga gcagtctatc agccttgaaa aacaactgaa
     3181 cattatacag gttgccgact tggtacttcc tgacaaggaa acttcctttg aggaatatac
     3241 cacaatggag ttactatcgg tagcaatgct gattgtcatt agtacctttg cgttggactt
     3301 tatccataca gaccgaagta ttttcaagat tgtagactta gacgaagcat ggagcttctt
     3361 acaggtggca caagggaaaa cactatctat gaagctggtt cgtgctggtc gtgctatgaa
     3421 cgctggggta tatttcgtga cccaaaatac agatgacctc ttagatgaaa aactgaaaaa
     3481 taacctcggc ttaaaatttg cctttcgttc cactgacctt aacgagatta aaaaaaccct
     3541 tgcctttttt ggtgtagacc cagaggacga aaacaatcag aagcgattgc gtgatttgga
     3601 aaacgggcaa tgccttatca gtgatttata tggtcgtgtc ggtgtgatac agttccaccc
     3661 tgtatttgaa gaactgctcc atgcctttga taccagacca cctgtgcgaa aagaggtgta
     3721 aatgtgaaac catcaatatt aaacagaata aaatcaaact ggacgctgaa acgtctaggt
     3781 aaagtggcaa tgacagtggc tttcacactt gtgattgcca tttttctttt agccatgctg
     3841 ggaacggtgg ttcaagctgc gggcttggta gatgatacgg tcaatgtggc aaatgaatac
     3901 agccgatacc cacttgaaaa ctatcaactg gatttttatg tggataatag ctggggctgg
     3961 ctaccgtgga actggtcgga cggaattgga aaacaagtca tgtatggact atatgccatt
     4021 accaatttta tttggacaat cagtctttat gtttccaatg cgacgggtta cttagtacag
     4081 gaagcctatt ccttagactt catttccgct acagcagatt ccattggcaa gaatatgcag
     4141 acccttgcag gggttacgcc tagtggacta tcaacagagg gtttctatgt tggattcctt
     4201 ttactcttga ttttggttct tggggtttat gttgcctata caggactgat aaagagagaa
     4261 accacaaagg caattcatgc cctcatgaat tttgtgctgg tttttatcct atcggcttcc
     4321 tttattgcct acgctcccga ctacattaaa aaaatcaatg acttttcatc agacatcagc
     4381 aacgctagtt tgtcactggg tacaaaaatt gtcatgcccc attcagatag tcaaggcaag
     4441 gacagtgtgg acttgatacg tgacagccta ttttccatac aggttcagca accgtggcta
     4501 ctgcttcaat ataacagttc agacattgaa agtattggta ttgaccgtgt ggaaagcctg
     4561 ctctcaacca gtccagattc caacaatggg gaagacagag aaaaaattgt tgcggaagaa
     4621 attgaagata gaagcaatac caatatgacg attacaaaga cgattaaccg tttaggtaca
     4681 gtcttcttcc tatttgtctt caatattggg atttccatat ttgtattcct attaacagga
     4741 atcatgattt tctcgcaggt actttttatc atctatgcta tgtttctgcc tgtgagcttt
     4801 attttaagca tgattccatc atttgatggt atgtcaaaac gagccataac aaagctcttt
     4861 aataccattt tgacacgagc tggaatcaca ttgattatta cgacagcatt tagtatttca
     4921 accatgctct ataccttatc ggctggttat ccgttctttt tgattgcttt tctacagatt
     4981 gtgacctttg caggaatcta ctttaagctg ggcgatttaa tgagtatgtt ttctctacag
     5041 agtaacgatt ctcaaagtgt gggaagtcgt atgatgagaa aacctcgtat gcttatgcac
     5101 gctcacatgc accgtctaca gcggaaactt ggacgctccg tgactgcttt aggggctggg
     5161 tctgccattg ccagtgctac gggtaaaaaa ggacagtcgg gttcgggaag ttctgcgagt
     5221 acacaagcag atcactctcg accaaacggg caggaaaaat caacactagg aaagcgtatc
     5281 ggtcaaacca tcggtacagt agctgatacc aaagacagaa tggtagatac tgctggtaat
     5341 ttgaaagaac aggttaagga tttgccgacc aatgcaagat atgcagtata tcaaggaaaa
     5401 tctaaagtga cggataatgt ccatgattta accagaagta tttctcaaac caaagcggat
     5461 aaagccagtg gacgcaagaa acagcaggaa caaagacgga aaaccattgc ggagcgtcgc
     5521 tctgaaatgg aacaggtcaa acagaaaaaa cagccagctt cttccgttca tgaaagacca
     5581 gccactaagc aagaacaatc tcatgatgga cagacttcaa ggcaaacaac tgtacaggct
     5641 tcctataggg aatctcaaca agccaaacaa gagcgtccaa cagttaagtc cgattcttca
     5701 agtttaaaaa cggaacgtca aagtaataca gttcaagaaa gaacggttca aaagccagta
     5761 acttcaactg caccaacaga tagagcttca caacgttcaa tcacaaaaga acgtcagtct
     5821 actgttcaaa gagtaccact acaaaataca aaaagtagac caccaatcaa aaccgccacc
     5881 attaagaaag gcagtaagaa accatgaagc tgaaaacttt agtgattggt ggttcgggat
     5941 tattcttgat ggtcttctca ctgcttctgt ttgtcgccat tttattttca gatgaacaag
     6001 atggcggttt ttccaacatt cactatggcg gtgtggatgt ttccgcagaa gtgctggctc
     6061 ataagcctat ggtagaaaaa gttgccaaag aatatggaat tgaagaatac gtcaatatac
     6121 ttcttgcgat tatacaggtg gaatcgggtg gtacagcaga agatgttatg cagtcctcgg
     6181 aatccctcgg tcttccacct aattcattga gtacagaaga atccattaag caaggtgtga
     6241 agtatttcag tgagttatta gccagtagcg aaaggcttgg tgtagattta gaatcggtta
     6301 tccagtccta caattatggt ggtggtttct taggatatgt ggctaatcgt gggaataaat
     6361 atacctttga actggctcaa agtttctcaa aagagtattc gggtgacgaa aaagtgtctt
     6421 accccaatcc catagccata cctatcaatg ggggctggcg atacaattac gggaatatgt
     6481 tttatgtgca actggtaacg cagtatcttg tcacaacaga gtttgatgat gatacagtac
     6541 aagccatcat ggacgaagct ctgaaatttg aaggctggaa gtatgtctat ggcggagctt
     6601 ccccgactac ctcttttgat tgtagcggac tgacacaatg gacgtatgga aaagctggaa
     6661 tcaacttacc acgaacagca caacagcaat atgatgtaac ccggcatatc ccattattgg
     6721 aagcaaaagc cggcgatttg gttttctttc attctaccta taacgctggc tcttatatta
     6781 ctcatatcgg gatttattta ggcgataacc gtatgtttca tgcaggcgac cctatcggtt
     6841 atgccgactt aacaagctct tactggcaac agcatttagt gggagcagga cgaatcaaac
     6901 aataagaaag gacgattcaa tgatgaaatt cggaaaaaat cagaatacag aaaaacagac
     6961 accaaaggaa aagaaacctc gtgtctataa ggtcaatcct cgtaaaaagg ttgtgattgt
     7021 cctatgggta cttttaggac ttagtttcag ctttgcgata ttcaagcact ttacagccat
     7081 tgatacccat accattcatg aaaccaccat catagaaaag gaatatgtcg atactcatca
     7141 tgtggaaaat tttgtagaga actttgcgaa agtctactat tcatgggaac taaacgacaa
     7201 gtccattgat aatcgcatag aaaacctgaa agcatatctg acagaggaac ttcaagctct
     7261 gaatgtcgat acagttcgta aagatattcc tgtatcgtct tctgtaaaag gatttcagat
     7321 atggacggta gaagcagatg gcgacaatca atttgatgta acctacagtg tagaccaact
     7381 cattacagag ggggaaaata caaagaccgt ccactctgct tatatagtga gtgtctatgt
     7441 agacagtact ggaaatatgg tcctcattaa gaatccgacc attactagca taccaaagaa
     7501 atcagactat aaaccaaaag ctattgaaag tgagggtacg gttgattcca ttacaaccaa
     7561 tgaaatcaat gagtttttaa cgacgttctt caagctctat cctacagcga cagccagtga
     7621 actttcctac tatgtgaatg acgggatatt aaaaccaatc ggaaaagagt acatctttca
     7681 agaactggta aatcctattt acaatcgtaa ggataatcaa gtcacggtat cgctgacagt
     7741 ggagtatatc gaccagcaga ccaaagcaac gcaggtatct caatttgatt tggtacttga
     7801 aaagaacggg agtaattgga agattataga ataacaaata ttggtacatt attacagcta
     7861 ttttgtaatc acgtactctc tttgataaaa aattggagat tcctttacaa atatgctctt
     7921 acgtgctatt atttaagtat ctatttaaaa ggagttaata aatatgcggc aaggtattct
     7981 taaataaact gtcaatttga tagtgggaac aaataattgg atgtcctttt ttaggagggc
     8041 ttagtttttt gcacccagtt taagaatacc tttatcatgt gattctaaag tatccggaga
     8101 atatctgtat gctttgtatg cctatggtta tgcataaaaa tcccagtgat aagagtattt
     8161 atcactggga tttttatgcc cttttgggct tttgaatgga ggaaaatcac atgaaaatta
     8221 ttaatattgg agttttagct catgttgatg c
//
LOCUS       DAXQKX010000089         8228 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.092, whole genome shotgun sequence.
ACCESSION   DAXQKX010000089 DAXQKX010000000
VERSION     DAXQKX010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8228)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8228)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8228
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.092"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            328..1251
                     /gene="truB"
                     /locus_tag="ACF3MF_002541"
     CDS             328..1251
                     /gene="truB"
                     /locus_tag="ACF3MF_002541"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HFE3928447.1"
                     /translation="MDGLLTLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEEKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVKRFKRVDITDEVWQKVKNGMRLNYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            1255..2196
                     /gene="ribF"
                     /locus_tag="ACF3MF_002542"
     CDS             1255..2196
                     /gene="ribF"
                     /locus_tag="ACF3MF_002542"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006747 - FAD biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009398 - FMN biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HFE3928448.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGEIWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            2591..3376
                     /locus_tag="ACF3MF_002543"
     CDS             2591..3376
                     /locus_tag="ACF3MF_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFE3928449.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWINNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENDKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            3389..4240
                     /locus_tag="ACF3MF_002544"
     CDS             3389..4240
                     /locus_tag="ACF3MF_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HFE3928450.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(4364..4816)
                     /locus_tag="ACF3MF_002545"
     CDS             complement(4364..4816)
                     /locus_tag="ACF3MF_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3928451.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQIREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNHVVNFSQWINEKLLMQTDISLVS"
     gene            complement(5281..5649)
                     /locus_tag="ACF3MF_002546"
     CDS             complement(5281..5649)
                     /locus_tag="ACF3MF_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HFE3928452.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            5799..6281
                     /locus_tag="ACF3MF_002547"
     CDS             5799..6281
                     /locus_tag="ACF3MF_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HFE3928453.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            6318..7328
                     /locus_tag="ACF3MF_002548"
     CDS             6318..7328
                     /locus_tag="ACF3MF_002548"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="HFE3928454.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPPWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQPSEKYQKEWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTISHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(7443..8156)
                     /locus_tag="ACF3MF_002549"
     CDS             complement(7443..8156)
                     /locus_tag="ACF3MF_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928455.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIKQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLINVIVMDN"
BASE COUNT         2784 a         1337 c         1667 g         2440 t
ORIGIN      
        1 ttaagaaact gaaaaaataa ataaaaaaaa acggaaaaaa gactggaaga atggacagtc
       61 ttttttttcg tttttgggaa gtgaaaacca aactatttac ctgtaagcca cccataaatc
      121 caatcaaatg gtgcaaagaa aaaatcttcc attctattcc ctcctttaaa aaaaacataa
      181 catgatttct atttacgtga gcatgaattt tgttacgttt ttattgccga aaaataaaaa
      241 ccgttcatta tgatgtcaaa ttcgtcagta attgatgcaa tgtgttataa taattcagtt
      301 aaatcaaaaa tgaaatggag aaaagacatg gacgggttat taactttatg gaaagaacgc
      361 ggaatgacaa gtcatgattg cgtattcaaa ttaagaaaaa tcttacatac gaaaaaaatc
      421 ggacatgggg gtacgcttga cccagacgta gacggtgtgt tgcccatttg tattggaaaa
      481 gccacaaaag ttatcgaata tttgacagat tctgggaaaa tctatgtagg cgagataact
      541 ctaggtttca gtacaacgac ggaagatcga tccggagaac gggtagaaac aaaaccagta
      601 gatatgtctt tatctgaaga aaaaatagat gaagtgatgg cttcatttat tggtgagatc
      661 acccagatac caccaatgta ctcagcggta aaagtcaacg gtaagcggtt atatgaatat
      721 gcccgcaata atgaaacagt ggagcgtcct gttagaaagg ctcagattta ccgttttatc
      781 cggacaagtg aattgacaag agacgaagtg acaggaacca tttcttggcg cttcgaagta
      841 gaatgcggga aaggaaccta tgtccgcaca ttagctgtag atacaggcaa gaaacttggt
      901 taccctgcgc acatgtctga tctgacccga acagcaagtg ccggtatgtc ccagaaagat
      961 gctctgacat tagaagaagt agctcaagct gtgaaaaatg ggacaatcga tgattgtttg
     1021 ctgccaatag aaaaaggagt gaaacgattc aaacgagtag atattactga tgaagtatgg
     1081 cagaaagtaa aaaacggtat gagacttaat tatactgtat ttgcgctccc agaaatgccg
     1141 tcagaagaaa ttgctttgtt ttataaaggc aaagttgtca gtatctatca gccaaacccg
     1201 aaagaaaaaa acaaattaaa acctagtaaa gtattgagaa atgaggaata acgaatgaat
     1261 atcatcaaga tcagacatcc ttaccaatca gaacaaattc cagaagacga tgtcgtttta
     1321 gtactaggat tttttgacgg cgtgcatatt ggacaccaga aagtcataaa gacaggtatg
     1381 gaaattgcac aaaaagaagg attgaaatta gcattgatga ctttcaatca gcatccatcg
     1441 attgtcttta aaaagatcga tcctagcagc gtgaaatatt tgactagcct taagcaaaaa
     1501 gaagaaaaaa tggccgcttt gggtatagat tatttatatg aagttgattt tacttcttct
     1561 tttgctcatt tagcaccgca ggaatttgtt gatcaataca tcgtagggtt acatgcaaaa
     1621 tatgctgttt ccggttttga ttatacgtat ggaccaaaag acattgcaga tgtcgctcat
     1681 tttcctgaat atgccaaagg aagattcaaa atcgtcacag tttctaaaga agaagaacaa
     1741 ggtgaaaaaa tcagctctac ccgtattcga ggattactag acagcggaca agtaaaagaa
     1801 gcagcaaaac tattaggttg cacatatgag gtagaagggg tagttgtcca tggcgatgca
     1861 cgaggcagac tactaggatt ccctacagca aatgtcaaag taaagagcac agttcatttg
     1921 cctaaagaag gtgtttatgt atcggaaata aaaattgggg aaatttggta tccagccatg
     1981 ggttcaattg gacataatga tacattcggt gaaggacggg agctgactgt agaattgtat
     2041 attttggact ttaatcaaga tatctatggt gaacatgtcg cagtacgctg gaatcaattt
     2101 ttaagagatc aagtgaaatt ttctagtgta gaggaattga ttgaacaact caaagaggat
     2161 gaacaagcaa cagctgaata tttttctcag caataaaaca ttatgcataa aatctcttgt
     2221 ttatgtataa ctagcaattt caataaaatg ggtgataaat aagcccagga aaggggctgt
     2281 gacaaaagtc ttgtcacagc ctttttttcc aaataaatgg tttttcagaa gtagcttctt
     2341 cggaaataag ccgaaatttc acaaaaattt gagaagtaat ttttgtaaat tacttcttat
     2401 ttcttgaagc tggccacttc tgtcacaacc tctttcttta tagaaataaa aggacactag
     2461 caattcatga aaacgattgc taaagcgtat catttgcttt agactatata tcttggtgta
     2521 cactcacttt aagacggaaa taaaagttat ccgtaataac aggtttaggt atgaaaaagg
     2581 agtgggtact atgtataagg aattagaaaa caaagtcgca gtagtaactg gtggctcaaa
     2641 ggggattgga acagcgattg ctcaacgatt cgggaaagaa aaaatgaatg tagttgtcaa
     2701 ctataactcg gataaagaag gagcagaaaa agcagtcaaa gcaatcgaag aggcaggcgg
     2761 aaaagcagtc tctgtacaag cagatgtcag ttctgaagaa ggaatacagc gtttacttga
     2821 tacggcttta gaaaattttg ggacactgga cgtttggatt aataatgctg ggatggaaaa
     2881 tcagcatcca acccatgaac ttagccttga agattgggaa agagtattaa aagtcaattt
     2941 gactggcgtt tttatcggaa cgaaagcggc tttaaattac tttacagaga atgataaaaa
     3001 aggaaatatc atcaatatgt cttctgttca tgaacaaatc ccatggccaa cgtttgctca
     3061 ttacgctgct tcaaaaggcg gagtaaaact attcaccgaa acggtagcaa tggagtacgc
     3121 accaaaggga atcagaatca atagtatagg acctggtgct atccgtacac ctattaatgc
     3181 ggcaaaattt gatgatcctg aacaaaaaga actcttggaa agtatgatcc cactaggacg
     3241 cgtaggtgaa ccaaaagaaa tagcggcgac agctgcatgg ttggcttcag acgaatccag
     3301 ttatgttaca ggtattacac tatttgcaga tggtgggatg actttatatc cttctttcca
     3361 aggtggaaaa ggataagggt gaataaaaat gggtttattg attgcattga tcccggcagt
     3421 tgggtggggg atccagccac tgattttgaa aaagattggt ggcagaccaa caaatgagat
     3481 attaggaact ggtattggag ccgtgctcgt tggcttactt gttcaattat tcgcttctcc
     3541 agctggtatt tcagtgacta catttttgat tagtttactt tctggtgcat tctgggtcat
     3601 cggacaaaca ggacagtata catctttcaa cttgattggt gtttctaaaa cgatgccaat
     3661 ttcgactgca ttacagttag tcggaacctc attgattggt gtcttcgctt ttggagaatg
     3721 gtctggaagt atgggaaaaa tcattggtgc agcagcaatc attcttcttg tatttggttc
     3781 tgctttaacg gcaatcagtg atgatcctgg aaaaaaaggc ggtatcacaa aaggaatcag
     3841 tctattagca tcaacaagta ttggttattg ggtttacagt gcattgccca aactagttga
     3901 tgcaagcgga ctttccattt tctttccgca aatgatcggt gtctttttag gggcagtgat
     3961 ttatgtgatt ttccgaaaac caaccgcatt ttctgaagac aagagttgga aagcaacaat
     4021 agttggagcc atcttcagtg tgtcagcatt ggcttatatt ttttcagcaa atgaaaatgg
     4081 ggttgctact gcatatatca ttacacagct aaacgtagtt atctctacat taggcggtat
     4141 gtacatcctg catgaaaata agacaccaaa agaaaaaaaa ttaacgatta tcggattatt
     4201 gctgatcgta gtaggaagca tggtcacggt ctttatttga ggataaagat ggtaaaatct
     4261 catttattaa aaaaatattt gtttgaacca aacagtaagt acttataaaa aaatagcgct
     4321 agaatttcca acatctctgg aatttctagc gctttttaat tgtttaagat acaagtgaaa
     4381 tatctgtctg catcaataat ttttcattga tccattgact aaaatttacg acatgattga
     4441 agttaccacc gattagtatc tccgcatgat tgtctttata aagatcgtat tgtaaaagac
     4501 ggtctttttt atttgcgtaa acatcgttat ggtactggac taattgttct cggatttgat
     4561 tgattgctgt aaaatcacga tactgaaggt tgaaacgcat cgtgattggt gcatttagca
     4621 tgaatcgctg catttctttt gctgcttcct ctgcttgatc tccgtatagg aactcaaaaa
     4681 gattacgttc agaaaatttc cattgcccgc caacctttgt tccttttagt tttccttcat
     4741 gaagataatt tctgatagaa cgtgtagtaa cacctaattg ttcggctaat tcatttactg
     4801 agtaaaaatc tttcaatgtt caccctccta tgtgaatggt tctactgact tagttgatat
     4861 ttgcttaatc acgaaatgta gaaagaacga ttttaattaa ggtcattgta aaaatcaagt
     4921 cagaaaattc taacttttct ttctctaaag aaattcgttc tctcctaaag tgatattata
     4981 tttaaatata cctgaaaata atgggcagta ttatgaaaga tcactgatat tttctcgtat
     5041 tttttcctta ttcaaaagtt ttgcaggaaa attgctgaaa aaataatttt actaagtgga
     5101 aaattcaaag ccattcaatc agtgattttt ttcagcacaa gaaagactcc ttataaaaat
     5161 agcagatact ttgtcaatta agtgtttaac cagggatgat aaaaaggata ggattgaaca
     5221 aaacctgtat aagctgatga atagtttcct cgccagtaaa aggtttattc gtataaagct
     5281 ttatcgccaa aatttatcat gacctttttt atcttcaata ttaaatgaaa tcaattgttc
     5341 aatcaattcc cagttgatta cacttttcca aggaactttg atgacgttat ccgtatatac
     5401 gtagcctgct tcttggatat ttttttcaag ggcacgaatc gctgcttttt ccggtgcgat
     5461 agaaaaatga tttttagcaa aactaaatgc aataataaag gtaccatggt cagtaaacat
     5521 aggttggttc cattttacag ttgtgtctag ctggggatac gtttctgtta tcttagcaaa
     5581 aaggtctttg atcttttgtt gatgttcttt ttctttgatc tgattgatga tcggctgaaa
     5641 tttttccatt ctaaaacgcc tccattaagt ggtttgattt attttaccag aaaaacaata
     5701 gttatgtata aaaaacgaac aaaacacaag taatgttgta accgctatat ttatatgata
     5761 agatgtctca aataataaaa tagaaaagag acataaaaat gattgacttg gcaaagaaat
     5821 tcttacacga aaatatatat tttgagttgt atcatcatcg agccatttat acaaatgaag
     5881 atgctttggt aataaagaaa gaacaaggat ttacaggtac agagaccaaa agcttattct
     5941 taaaagataa aaaagataat aactacgtat atctgacttt tactacgaaa caaacggatt
     6001 tcaaagcatt agggaagatc gtcggtaaaa ggctttctat tgtttcatca gaacgcatgg
     6061 aagaacaaac gggacaaaag cagggcgctg tttctccgtt tggttatgaa aaacagattc
     6121 cgattattat tgatgaagag ctcttatcaa atgaaaaact tgtttttgca ccaggtagac
     6181 cagatcaaac gatggtcatc caaacggttg acttaaacaa aatcatccag ctacttgaga
     6241 tgccgatatt tttgatgccg gcaaacgaaa aaaacaatta accaagtaaa atagtgcata
     6301 cttggaggtg aagcaacatg ataagttatc cattattaga aagaaatgca acgattgggg
     6361 ttactgcacc atcctcaggc gtatcagagg aacaccattc gttactcgaa tcagctttaa
     6421 agagaatgga agaaaaatct ttccaagtag ttactggaaa gacgctttgg acgcaagata
     6481 aggaaaaatc aggtccagca agaaaacgag cagatgaatt caatcaaatg atgcaagatg
     6541 aaaatatcca aatgatcttt ccgccttggg gaggagaatt attgattgag attctcgatt
     6601 ttgtcgattt tgatgctcta caaccaaaat ggatagtagg ttattcagat attagtacgt
     6661 tgctacttgc tgtcacatta aaaacaggga tagccactgc acatggaacc aaccttattg
     6721 atttaagagg agagtacttg gatgaaacga cagcaatgtg ggaaagtgta ctgaaaacaa
     6781 gagaaggaga atcgattcta cagcaacctt ctgaaaagta tcaaaaagag tggccccatg
     6841 agcattcatc atcttctgtt ttccatctca ctgaaccaac aaattggcaa tcagtcagcg
     6901 gagatgcagt aaggatgaag ggacgattat taggtggctg tattgatacg atcagtcatt
     6961 taatcggtac cccttatgga gatgtccaat cttttaaaag aaagtataat gatggaaagc
     7021 cgatcttgtg gtttctagaa aattgtgagc tatcgtcagt tgatttaaga agatcacttg
     7081 ttcagatgaa actggcagga tggtttgatg gcagctcggg gatcatgttc ggtagaagtg
     7141 cagcagagga tttgttagat tataaaatga aggatgtata tgaagatctg tcaaaggaat
     7201 taaaactacc gatcttgtat gatattgatt gtggtcatgt accgccacaa ctgacattga
     7261 tcaatggtgc ctatgcagaa gtagcggtag aagatagaaa agcgactgtt ttgcaaacgt
     7321 ttatttaaaa aattttttcc tgccttggag tttatcaaag accaacaaat ctaaatagaa
     7381 aagaaaatga aagaagctga cagtattttg ccagcttctt tttgtatgat ctattagaaa
     7441 ttttaattat ccataactat cacattgatc agctgtttca catcatttgg attacctgta
     7501 ggaatagcta ctacagatgc attatcaata atttcttgag ttgtttctct aatgaacgct
     7561 ggataagatg tttgatctgc aggcatttgc caatgtgaag gaactggata actagtgatt
     7621 gtcccgtcat ggttacttga atacactaaa actccctggt aactgtattt cccagtgagc
     7681 ataaccacat ctttcggata gactgcactc cctgcatcat aaggggcgat aggtgttcct
     7741 gcaggataat gaataacatg tagttcgaaa tcacccgatg tatctctaaa agtattacct
     7801 ctaattgcta gccaaacacg tgcgtactca atttgtagat cagaatatcc tgctaacgga
     7861 tctattgact gagaagactg tgaggaagtt gtgtctattg ttgaagaaga aatatttgtc
     7921 tcaactgtac tactagatgt agaagaagta ttgggctctg agactttact gcttgttgaa
     7981 gatgtattcg tttcagtaga agctgatttc tgagtacttg atttttcagc tgaactggtt
     8041 tgtttgattg aacttttgtc tgtggtcgca gatggatcac tattttcttt actaggagac
     8101 gtacatccta caaggaataa agagaccaac aataaaataa aacctaactt tttcatataa
     8161 aatacctcat tattttttta ataccagtat agcataatcc tgaatttttg aatccgtaaa
     8221 accttgtc
//
LOCUS       DAXQKX010000090         8210 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.093, whole genome shotgun sequence.
ACCESSION   DAXQKX010000090 DAXQKX010000000
VERSION     DAXQKX010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8210
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.093"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(63..230)
                     /locus_tag="ACF3MF_002550"
     CDS             complement(63..230)
                     /locus_tag="ACF3MF_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928456.1"
                     /translation="MYRPQYLEQKYEVITVQNGNGEIVRKYRRPIKSDTYKRKESNEV
                     IPLYGKRIAKH"
     gene            complement(267..641)
                     /locus_tag="ACF3MF_002551"
     CDS             complement(267..641)
                     /locus_tag="ACF3MF_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928457.1"
                     /translation="MEDKMYLRQKVFTKKDIENQINGFIQKLENANSYLINKELNKAY
                     DQWKEVYDELKLIQNETKLVRTEKKNENSFFFDGYAILMLETVAKQNIKAPKKELSDN
                     IDNALAELRYYVMQIKDVRITR"
     gene            complement(987..1400)
                     /locus_tag="ACF3MF_002552"
     CDS             complement(987..1400)
                     /locus_tag="ACF3MF_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family phage packaging/lysis
                     transcriptional regulator"
                     /protein_id="HFE3928458.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGRIIAYK"
     gene            complement(1476..1772)
                     /locus_tag="ACF3MF_002553"
     CDS             complement(1476..1772)
                     /locus_tag="ACF3MF_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928459.1"
                     /translation="MKLKDGFYSSSHGIGGLMLDMPTKNPKTRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHLYNHSAIIRIENTMECDKWLAKSKDNLAVVRLVDIELINDK"
     gene            complement(1772..1978)
                     /locus_tag="ACF3MF_002554"
     CDS             complement(1772..1978)
                     /locus_tag="ACF3MF_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928460.1"
                     /translation="MKIYVVKFGNQFYRSDERSIGANTLSIVDILQSARWFDNLEEAN
                     QVSRRLGGLAQVYELVTIDHEEVE"
     gene            complement(1975..2172)
                     /locus_tag="ACF3MF_002555"
     CDS             complement(1975..2172)
                     /locus_tag="ACF3MF_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HFE3928461.1"
                     /translation="MNNRHRRVTKLRKQELNALKAKFEKEYGISIEEAYKVASQCVAD
                     ASEAIRKFGISILDIKWEDTE"
     gene            complement(2179..2409)
                     /locus_tag="ACF3MF_002556"
     CDS             complement(2179..2409)
                     /locus_tag="ACF3MF_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928462.1"
                     /translation="MKYEIALSEADVQSIINGRKVKFKLSDGTEIVIRQSYLKDMAAP
                     VLIDRFNVTDSVVENHLKEFRSSINDTFRLGS"
     gene            complement(2432..2737)
                     /locus_tag="ACF3MF_002557"
     CDS             complement(2432..2737)
                     /locus_tag="ACF3MF_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928463.1"
                     /translation="MNVQVYLKRDLARFPRSWDEYSCPFEAEEESYLMSANMIEITRD
                     DADEVDKKRSWYSVSNPMYTAVIEDYHISDRFILVDLERPKKRIKQYRRCGFSTKKW"
     gene            complement(2734..2931)
                     /locus_tag="ACF3MF_002558"
     CDS             complement(2734..2931)
                     /locus_tag="ACF3MF_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928464.1"
                     /translation="MKAYTIKFYGNKTFVYILSGLRLDFRGYSKEDLLESLYGYGYLN
                     EDELISLEKFTNAWTIEEEAE"
     gene            complement(2934..3209)
                     /locus_tag="ACF3MF_002559"
                     /pseudo
     CDS             complement(2934..3209)
                     /locus_tag="ACF3MF_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876801.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
     gene            complement(3364..3561)
                     /locus_tag="ACF3MF_002560"
     CDS             complement(3364..3561)
                     /locus_tag="ACF3MF_002560"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928465.1"
                     /translation="MNKNKQELINELKRISLEKQHKALTHPESKNYYEGMVMAYSQVV
                     HMVNTVLKLDESQKPVMPKFF"
     gene            complement(3554..3874)
                     /locus_tag="ACF3MF_002561"
     CDS             complement(3554..3874)
                     /locus_tag="ACF3MF_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017547333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HFE3928466.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKATANIEFYYNEIQKGFEQMRELDKQTNWRKKLHQDRFKFVEKYKEILDEYLE
                     DSNE"
     gene            complement(3874..4179)
                     /locus_tag="ACF3MF_002562"
     CDS             complement(3874..4179)
                     /locus_tag="ACF3MF_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928467.1"
                     /translation="MSVDKKAAMKRIIELTHSENWQEDKEAASEVMRLGRTMWADKSN
                     KPRPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRAKRENVDSKGRQFKHVEEK"
     gene            complement(4176..4337)
                     /locus_tag="ACF3MF_002563"
     CDS             complement(4176..4337)
                     /locus_tag="ACF3MF_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HFE3928468.1"
                     /translation="MTTEEVIQMRIRSIQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            complement(4334..4636)
                     /locus_tag="ACF3MF_002564"
     CDS             complement(4334..4636)
                     /locus_tag="ACF3MF_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928469.1"
                     /translation="MDKKAAMQRIIELTYSEDWQNDKEAASEVMRLGREMWADKSNKP
                     RPRKIAIWHGDKILVTGTAQQLATLTGLHEKIVRKRARCGYTDVKKRTFRYMEESS"
     gene            complement(4629..4793)
                     /locus_tag="ACF3MF_002565"
     CDS             complement(4629..4793)
                     /locus_tag="ACF3MF_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928470.1"
                     /translation="MDLKTFTAQIELMHQEALRQSASYEDKWLNTFHGGRESALDQVL
                     KLLKGERRDG"
     gene            complement(4798..5067)
                     /locus_tag="ACF3MF_002566"
     CDS             complement(4798..5067)
                     /locus_tag="ACF3MF_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928471.1"
                     /translation="MKIDYLELINEIASYKTGEEIEILRDVYEQLDEAGIERIKNDRS
                     SWSKLRYYFALYIDATQLRNLAYTKLLFVDCVKGLQKHLSELEQV"
     gene            complement(5079..5927)
                     /locus_tag="ACF3MF_002567"
     CDS             complement(5079..5927)
                     /locus_tag="ACF3MF_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replisome organizer"
                     /protein_id="HFE3928472.1"
                     /translation="MAERRMFAKTIIDSDAFLDMPLSTQALYFHLSMRADDDGFINNP
                     KKIQRMVGCGDDDLKLLMVKRFILVFESGVIVIKHWKIHNYIQKDRYKPTLYQDEKAQ
                     IAVKETNAYTFIENLPEPSETPMEQPFEDVYPSCIHDGYSLETQVRLGKDRLGKDSKE
                     IKDITPSKKSKTKPIRHKYGEYKNVLLSDEQMGKLKTEFPNDYQERIERLSEYCESSG
                     KTYKNYLATIRSWARKEKSEPKNASSAYKRTGRREKLPEWAIDQEAYQKKKALERANR
                     QSKAPF"
     gene            complement(5930..6157)
                     /locus_tag="ACF3MF_002568"
     CDS             complement(5930..6157)
                     /locus_tag="ACF3MF_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928473.1"
                     /translation="MINLNAVAFEQTWRTKYKKMSPRDKLFLEIMTFAFVGTQAEQSD
                     ISVEKIKTNRLVNGIIETCYQYTINVVDEEE"
     gene            complement(6160..6846)
                     /locus_tag="ACF3MF_002569"
     CDS             complement(6160..6846)
                     /locus_tag="ACF3MF_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative HNHc nuclease"
                     /protein_id="HFE3928474.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDIGATINEEVNIERLKTMYDGYDGD
                     RIIEVRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
     gene            complement(6852..7523)
                     /locus_tag="ACF3MF_002570"
     CDS             complement(6852..7523)
                     /locus_tag="ACF3MF_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HFE3928475.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     IIEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            complement(7516..7794)
                     /locus_tag="ACF3MF_002571"
     CDS             complement(7516..7794)
                     /locus_tag="ACF3MF_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017547334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928476.1"
                     /translation="MKETNNRKIRRNLLTNEELSCDQDDLGNFVSIWDHVYLIHLSKH
                     SNKPEYIYVIEDGLIDALEEYNRDNLIDISYYGSGKKYIAEMEAEFDE"
     gene            complement(8031..>8210)
                     /locus_tag="ACF3MF_002572"
     CDS             complement(8031..>8210)
                     /locus_tag="ACF3MF_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HFE3928477.1"
                     /translation="SKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEI
                     DQLNRQQRLFGDENE"
BASE COUNT         2107 a         1804 c         1232 g         3067 t
ORIGIN      
        1 tcaactgtaa tagccatcta tagaattcct cgttcatgtc ccgtctcctt tcacaatctt
       61 atttaatgct tagctattct tttgccatac aatggaataa cttcattgct ttcctttcgt
      121 ttatatgtat cgctctttat tggtcttcta tactttcgta ctatctctcc gttaccattt
      181 tgcacagtga ttacttcata cttctgttct aagtattgtg gtctatacat tgttgttacc
      241 tcctttgtgc aaaataaaaa gaccactcaa cgagtgatcc taacatcttt tatttgcata
      301 acgtaatacc ttaactcggc taatgcgtta tcaatattgt cagatagttc ttttttggga
      361 gcttttatat tttgttttgc tacagtttcc aacatcaata tagcatatcc atcaaaaaag
      421 aaactatttt cattcttttt ctccgttcgt actaattttg tttcattttg aatcaatttc
      481 aactcatcat atacttcttt ccactggtca taagctttat ttagttcctt atttatcaaa
      541 taagaatttg cattttctaa tttctgtata aatccattaa tttgattttc aatatctttt
      601 tttgtgaaaa ctttttgtct taaatacatt ttgtcttcca tgcactctca cccctttcgt
      661 aatattttta ttatatcatt ttttactatg tacaaatagg aacagcttac atctacaaac
      721 aacagttttt ttaagttgag taaatactca ataaaaccga aagagttgca attaatagac
      781 agcaacacat gaactaactg taggagctga cccccacatc ctttagttta tttgctgctg
      841 tctatcgaag cttaattaaa cgatgaggga gatttcctcc cttacatttt attttgtctt
      901 agacctatca ctaatctttc gacactacca taatatcact ggtaaatagc taaaaaccgc
      961 catcattccg ccaaaaaacc gccaaattat ttataagcaa ttattcttcc gtgtttatat
     1021 gcttctgcaa actctattag agcttccgac ttcatccgtt gtatacttct ttctgaataa
     1081 cccacttcac ggctaatcct gtagtttgag aagctatctg gcacacagaa gctgtagtag
     1141 agtatctggc gactaattag actaagagcc atcaaagccg ctagaatcgc atctctctcc
     1201 gcttctatat ccatcatctg aatgatcgcg tcttctgcct tattgccgtg ctttggtgcc
     1261 ttcggcatat ccgtaataat cggcgactta atatctatca aagagcgacc tgccatccgc
     1321 tccaagcgcc gaaagttctt cagcacatct ctcgcattac atcttgtctg tttgaaatct
     1381 acctctcgta acaattgcat caagtcaaac cgctccttta tgtgatataa taaacttgtg
     1441 gaatttatta gatcagtcgg agcgatccgg cttttttatt tgtcattgat tagttcaata
     1501 tccaccaatc tcaccactgc taaattatct ttgcttttcg ctaaccactt gtcgcattcc
     1561 atcgtgtttt caatgcgaat gatcgctgag tgattataga gatgctctac atatccacga
     1621 aacggataga tgaacccttc tgcttcgcag cgaaccatgt caccgacttt gaattttggt
     1681 ttcttacgtg ttttagggtt ctttgtcggc atatctagca ttaaacctcc gataccgtga
     1741 ctgctagagt agaatccgtc ttttagtttc attactctac ctcctcgtga tcgatagtga
     1801 ccagttcata tacttgcgct aatccaccaa gtcgtcgtga aacttggtta gcttcttcga
     1861 gattatcaaa ccatcttgca ctttggagta tgtctacaat ggataatgtg ttagccccta
     1921 tagaacgttc atcacttctg taaaattgat ttccaaactt tactacataa atcttcattc
     1981 tgtatcctcc catttaatat ctagtatcga aattccaaac ttacgaatag cctcactcgc
     2041 atcagcaaca cactgacttg ccactttgta tgcttcttct atagaaattc cgtattcttt
     2101 ttcaaacttc gccttcagtg cattaagttc ttgttttctt agttttgtta ctctgcggtg
     2161 tctgttgttc attgtcaatc aactccctaa tctgaaagtg tcgtttatac ttgatcgaaa
     2221 ttctttcaag tggttctcta ccacagaatc agtcacgtta aaacgatcaa ttaatacagg
     2281 agctgccata tctttcaaat aactttgtct gataactatt tcagtaccat cagaaagttt
     2341 gaatttaact ttgcgaccat taataattga ctgaacgtct gcttcgctta gtgctatttc
     2401 gtatttcatt ctgcttcctc ctgttttatt ttcaccattt ctttgttgaa aacccgcaac
     2461 gtctatactg tttaattcgt ttcttaggtc tttctagatc aaccagaata aatctgtcgg
     2521 atatatgata atcttctatt acagccgtat acattggatt cgaaaccgag taccatgatc
     2581 tttttttatc aacctcatcc gcatcatctc ttgtaatttc tatcatgtta gcagacatta
     2641 gatagctctc ttcttctgcc tcgaatgggc aggaatattc atcccagctt cgaggaaacc
     2701 tggccaaatc tctttttaaa taaacttgaa cattcattcc gcttcctcct caatcgtcca
     2761 agcatttgta aatttctcta agcttattag ttcatcttca tttaaatatc cgtaaccata
     2821 taaggattct aaaaggtctt cttttgaata gcctctaaaa tcaagtctga gaccgcttag
     2881 gatgtataca aaggttttat ttccataaaa cttgattgtg tatgctttca tttctattcc
     2941 tcttgttcta atccttctat cactggcaca gcaaatggcc aatatctttc atcaattgct
     3001 tttatttctg attccgtaaa tttcatatca tcaaaatcat tgttgtctgc aattgttata
     3061 tttcctcgat catctttcat tagatacgtc tctaaatcca aatgattaaa atacacaact
     3121 ggtaacttca cataatacaa cggttctttc tcaacctcgt aaccatacag caacgcattt
     3181 attgcttttt ctttattaag ataaaggcta tcttcaacaa gccaatctag taactctctt
     3241 gttgtggaag aattttcgct tttaccaagt tcatagtcca cgccataacc ccaacctgca
     3301 cgtgcaataa gagaaatggc ataaaacttg tcacgttctg ctataactct ttttgcccaa
     3361 tcatcaaaaa aacttaggca taactggttt ctgcgattcg tctagtttta acaccgtatt
     3421 aaccatatga acgacttgag aataagccat caccatgccc tcatagtaat ttttgctttc
     3481 tggatgcgtc agggctttgt gctgtttttc tagtgaaatt ctctttagtt cattaatcaa
     3541 ttcctgttta tttttattca ttgctgtcct ccaagtattc gtctaatatc tctttatatt
     3601 tctctacaaa tttgaaacga tcttgatgaa gtttcttcct ccaattcgtt tgtttatcaa
     3661 gctcgcgcat ctgctcaaag cctttttgaa tttcgttgta ataaaattca atgtttgctg
     3721 ttgctttcca atgcctgcta cttcgcactc ctgctcctgt ttcagccatt tctaacttaa
     3781 ctaattccgc tcgttctttt gattttttat ctttctgaat cttcatcatg attttcttga
     3841 ggatgatatc actgtattgt gtaatgagat ccattatttc tcctccacat gtttaaattg
     3901 acgacctttc gaatcaacgt tctcgcgttt agctctatcc cagataatgt ttttgcttag
     3961 tccagtaatt tcagataact gttcagcagt acctgttact agaattcgat caccatgcca
     4021 gattgcaatt tttcgtggtc ttggcttgtt gctcttgtct gcccacatcg ttcttccaag
     4081 cctcatcact tctgaagcag cttctttgtc ttcttgccaa ttctcagaat gtgtcagttc
     4141 aatgattcgt ttcattgctg ctttcttatc cacactcatt cctccaatct acgaatttcc
     4201 cttcttaaat tctctatgtg taaatcaatt gcctttctcg ccgtttcatt gaccatcact
     4261 gcctttgtcc gctccagatc gtcaatctca cgttgaatgc ttcgaattcg catttgaatc
     4321 acttcttctg ttgtcatgat gattcctcca tgtacctaaa cgttctcttc ttaacgtctg
     4381 tgtatccaca cctagctctc tttctcacga ttttctcgtg caatcctgtg agagttgcta
     4441 actgctgggc agttcctgtg actagaattt tgtcgccatg ccagattgcg atttttcgcg
     4501 gtcttggctt gttgctcttg tctgcccaca tctctcttcc aagtctcatc acttccgaag
     4561 cagcttcttt gtcattttgc caatcttctg aataagtcaa ttcgataatt cgctgcattg
     4621 ccgctttctt atccatcccg acgttcccct ttcaataatt tgagtacttg atcaagtgcg
     4681 ctctcacgtc caccatggaa cgtgttgagc cacttgtctt cgtacgaggc gctttgtctt
     4741 aaagcttctt gatgcattag ttcgatctgt gctgtaaatg tttttagatc catctgatta
     4801 cacctgctca agttcactaa gatgtttttg caatccttta acgcaatcaa caaatagtaa
     4861 ttttgtataa gctaaatttc ttaattgtgt tgcatcgata taaagtgcga aatagtatct
     4921 gagtttactc caacttgaac gatcattctt aattcgttct attccagctt catcaagttg
     4981 ttcataaacg tctctcagaa tctctatttc ctcaccagtt ttgtaacttg ctatttcatt
     5041 gatcagttct agataatcga ttttcaattt tccacctctt agaatggtgc ttttgattgt
     5101 ctattagctc gttctagcgc ttttttcttt tgataggctt cttggtcgat tgcccattct
     5161 ggaagcttct ctcgtcgtcc tgtgcgcttg tatgcactgc ttgcgttctt aggttcactt
     5221 ttttctttcc ttgcccaact tcgaatagtt gccaaatagt ttttataagt cttaccagat
     5281 gattcacaat actctgacag tcgttcgatt cgctcttggt agtcattagg gaattctgtt
     5341 ttgagtttcc ccatctgctc atctgacaaa agaacatttt tatactctcc gtatttatga
     5401 cggatgggct tagtcttcga ttttttcgaa ggcgttatat cttttatctc tttactatcc
     5461 ttacctaacc tatccttacc taacctaacc tgtgtctcca aactgtatcc atcgtgtata
     5521 catgatggat acacatcttc gaaaggttgc tccatagggg tttcagaagg ttctggtaag
     5581 ttttcaataa aggtataagc attcgtttct ttcacggcta tctgggcttt ttcatcttga
     5641 tataaagtag gcttatatct gtctttttga atatagttgt gtattttcca atgcttaatg
     5701 acgatcacgc cactttcgaa aactaagatg aatcttttta ccataagcag ttttaaatca
     5761 tcatcgccac aaccaaccat acgttgtatt tttttgggat tattgataaa tccgtcatca
     5821 tctgcgcgca ttgatagatg gaaatataat gcttgtgtcg ataaaggcat atctagaaat
     5881 gcatcagaat caataattgt ctttgcgaac attcttcttt ctgccaaaat tattcctcct
     5941 catccacaac gttaatcgtg tactggtagc aagtctctat aattccgttt actaatctat
     6001 ttgtcttaat tttttcaaca ctaatatcgc tttgttcagc ttgtgtacca acaaaagcaa
     6061 atgtcatgat ttctaagaac aatttgtctc ttggactcat ttttttatac ttagtgcgcc
     6121 atgtttgttc gaacgctact gcgtttaaat taatcatcat tagcccccga ttcttaattt
     6181 cttaattgtc tcctggttta acttgatccc tttgatttga tatttatttt tgaaattgat
     6241 cacacctatt ttgtgtttct ccgtatgatg gattctgcag agtgctgcaa atgtgtactc
     6301 tgaatgatca acttctttgc gctttcgtct tcctaacgct ttgtcaaagt gatcgatatc
     6361 agctcctgtt ttgccacaga tacagcagac tctttttgtg atgcatttgt agaagtaata
     6421 ctcttgattc gctggtaaaa tctcataacc ttctttgaaa ggaatatgat gttcaaagat
     6481 gaaatctaag atgatatttg ctaagacgtt agcatcactc acggttgtat tcgattcgtc
     6541 tttgaggctt attttgcgcc ctgtgacacc ttcaaaacgg aagtagaaga attccttcca
     6601 gaagtccgtt ggcatgcctg tatcgataaa aatatcgcct atcagcgcat agatgaagtt
     6661 tcgttgctgc acagtaaatc gacgtggatc aataaatcga acttcaataa tccgatcgcc
     6721 atcatatccg tcgtacatcg tcttcaaacg ttcgatgttc acttcttcat taatagttgc
     6781 acctatgtct tttcctttga actttttcag aaccgctgaa tatgaatcga ttaatggttt
     6841 aaacactcat atcacttctt atctaattct tttctcttag ctgctattgc tcgctccatc
     6901 aaggcacatt gctcatagct taactgttca atagtttcaa cgttatcagc taagagccct
     6961 aatttatctg tctgctcatt aacatattcg attaaggtct tggtcatatc tttacccatc
     7021 tgctcattga aagcttctat aatcgtctct agcatgttta atttctttgt atcgattcta
     7081 ggtggtgttg gaatatcttc cccttgaaat acatataatc ccagtccgtg tagagccaat
     7141 gctttcacaa agcatcgctt caatgagtta ttgatttgca ttgcatttgg tttaacaact
     7201 ggttggtttc gataatctaa aacaggaaat aactctgttt ccgtatgtcc tttaaccgtt
     7261 actgagacag atacataagt ccctgtttca tccataagaa aaggtttata ttcctcaaca
     7321 agaaagtctt gatgagttcc agaaacaacc ctgtagtgtt tatactcatt aatagttacc
     7381 gttgcctgtg gatcattctt tttcataatc tcccacgcgt gagcccaaga taaataatca
     7441 aaatttcctt ttttcttgag aattttattt aacttacgac taaaaagttt ttcaaagttc
     7501 gttgtccctt tgatttcact catcaaattc tgcctccatt tcagcaatgt atttcttacc
     7561 tgatccgtaa taagagatat caatcaagtt atctctgttg tactcttcta gcgcatcaat
     7621 caagccatct tcgatgacat agatgtattc aggtttattt gaatgttttg atagatggat
     7681 aaggtaaaca tgatcccaaa tactcacaaa atttcccaag tcatcttgat cacatgatag
     7741 ttcttcgttc gtcaaaagat ttcgtctgat ttttcgatta tttgtttcct tgatattcga
     7801 cttgccctat tcagaatcag tcaaatattg atctaaagtg gaaagttctt tattcatatg
     7861 ctaaaattct ccttagatat gttttgtgac tctatgcttg ccggctgagt cactttttta
     7921 tttgttgcca tgctttttgc ttttcgatat gttgttggct taggatgttt ggtttattgt
     7981 gtctccacca gcgattagca attaccgtcc ctattcttag cgcttcagct ctattcattt
     8041 tcatcaccga aaagtctttg ttgtctgttc agttgatcga tttccatgcg gatcgcagtt
     8101 tctggtaacc acatttcaat aaatgaaaca gcatcatcga atctcttacg aggtaactcg
     8161 ccatatcttg ggattgaaaa ggtacgttta aattcagacc aaaattttga
//
LOCUS       DAXQKX010000091         8207 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.094, whole genome shotgun sequence.
ACCESSION   DAXQKX010000091 DAXQKX010000000
VERSION     DAXQKX010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8207
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.094"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            256..1044
                     /locus_tag="ACF3MF_002573"
     CDS             256..1044
                     /locus_tag="ACF3MF_002573"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928478.1"
                     /translation="MEKINESKVSVCKEKGESYFLETLSLKQQEDKLFSEWEKEECLK
                     GYYGINQDGLADESSYLQSLPKIAFILKEAYGKENFDMRPYYYDGAHAGSKTWRTAPL
                     WIAGISKIYEENKSTIAQIKTEKRNMGWKEFNQEYIRKVAILNLNKQCTTNGKLTDRK
                     YFQSGIDNKKFINKQIEIYNPEIIICGGTFYPFYDRIYDYKNFDTKYESANQNKQYAE
                     GYKDKKGRLIINTFHPGAIKKEEPWYDSIMEIVERFKSEGLFAK"
     gene            complement(1130..1234)
                     /locus_tag="ACF3MF_002574"
                     /pseudo
     CDS             complement(1130..1234)
                     /locus_tag="ACF3MF_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360751.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(1575..2039)
                     /locus_tag="ACF3MF_002575"
     CDS             complement(1575..2039)
                     /locus_tag="ACF3MF_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928479.1"
                     /translation="MPRINRKKPTGDFESVFDEELEELETPNDTIDSIPETEVTVSNS
                     FPSDKETITENFNEANRFGLSKTSKSTSSELVARTFKYKKETIQRVESLVYKDQRHSK
                     KIPGTKGFISDFMDNAIWQHLLQLGLATEEEVQKHLNSYSKYPLNFDNYEKK"
     gene            complement(2039..3004)
                     /locus_tag="ACF3MF_002576"
     CDS             complement(2039..3004)
                     /locus_tag="ACF3MF_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFE3928480.1"
                     /translation="MAVVLTVAANKGGVGKTLITINLAGAIRRSFPEAKILVVDTDAQ
                     GNSTKSFRVKVAKDQNTIYDVFMDNATVEETIVQTYDDHIDVLPANSDNNYLEFDKME
                     QFRDTILEWFVSLLKKFKDNLTEIMTVSGLKKKMNNIIDPSANYFNALDGKFDNVSDK
                     YDYIIFDTPPELKQVTSSVLSIADVVIVPYEPDLNGVDGVTHLISRVNTLKEKYNPNL
                     RIGGVLANKVYNTNLHAKMINAMMKYTNRNNYHYFDSELPRSITFADKLVRNGMPITM
                     SSPENKFAQHFYKLIIEMNKLGLLSKNGKELEIPHKLYVESDGEE"
     gene            3391..3717
                     /locus_tag="ACF3MF_002577"
     CDS             3391..3717
                     /locus_tag="ACF3MF_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFE3928481.1"
                     /translation="MKKNSKEFRNEYDRFVLKFLIDNYYISRIDLSKAIGLAPSYVRE
                     FYNGSRSFGNEALEKLESTIFNLYKPLLENHSFELNQVQEMIESIDSEEELELFRLKG
                     ANVLDI"
     gene            4102..5595
                     /locus_tag="ACF3MF_002578"
     CDS             4102..5595
                     /locus_tag="ACF3MF_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HFE3928482.1"
                     /translation="MTASLDVVYSTILQNGIRKFKYKNSRLKPVSFSEQTGKGAIFAY
                     RSKEHMVEGIGLVITSEEGIIENNNAFSHWTPNVFRYGTYTDEGRMFTKGHSEDNLRQ
                     INTFFVDFDTLDPNFDYGEILLASHELGFMPTMVLRTPHGYQAFYVLDQPAFVTKKSN
                     FKVINVAKMISNNLRKTLAKDFPVDVNANHFGITRMPNEDNTLFFEPQYRYSFADWIN
                     WSMRVDADKAVTYRNVFELPSNQDFRQVDEPWFRLLMRSEKIKGEKGRYGRNNVIFTL
                     SLAYFSSGYEIEECELAMLEFNDRLAYPLTDRELTRIIRSAYSGKYQAAHREKIILLC
                     QEWIDENLSEEQLFNKKKGWWKFKKERKVRKYSHSHEWAQDLLAYLNQQSYTYKPYIV
                     STKKELREELKIPERSLDKVLKQLKNENKIYYRVRSGRNGGITLASVHGLMRSIIRVK
                     KEVQEAYFSAISEVFGLARTFIYSTLEQLIEAPKKAEQMELFEVDTG"
     gene            5753..6037
                     /locus_tag="ACF3MF_002579"
     CDS             5753..6037
                     /locus_tag="ACF3MF_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HFE3928483.1"
                     /translation="MGVNTFVYPYPVSVFIIQRLGMTVEEFCELHGYRQSTVATWAYR
                     NRPVKVLPCDFLYCLSLASGLSMDKVYQDLLLLEEKFLQSLDPKKEKKSI"
     gene            6073..6198
                     /locus_tag="ACF3MF_002580"
     CDS             6073..6198
                     /locus_tag="ACF3MF_002580"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928484.1"
                     /translation="MFRVEIVEKKTIEKLEKAVNNILISKGDKVQTIEYAAVKKI"
     gene            complement(6425..7105)
                     /locus_tag="ACF3MF_002581"
     CDS             complement(6425..7105)
                     /locus_tag="ACF3MF_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HFE3928485.1"
                     /translation="MNHFKGKQFQKDVIIVAVGYYLRYNLSYRDVQEILYNRGINVSH
                     TTVYRWVQEYGKLLYNIWKRKNKQSIYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKQFDEPRVLVTDKAPSIASAFKKLQAHGFYQRTEHRTVK
                     YLNNLIEQDHRPIKRRNKFYRSLRTASTTIKGMEAIRGLYKKNRKEGTLFGFSVCTEM
                     KILLGIPA"
     gene            7291..>8207
                     /locus_tag="ACF3MF_002582"
     CDS             7291..>8207
                     /locus_tag="ACF3MF_002582"
                     /EC_number="5.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
                     /protein_id="HFE3928486.1"
                     /translation="MSTVILAEKPSQALAYASALKQSTKKDGYFEIKDPLFTDETFIT
                     FGFGHLVELAEPGHYDEKWQNWKLESLPIFPDRYDFEVAKDKGKQFKIVAELLKKANT
                     IIVATDSDREGENIAWSIIHKANAFSKDKTFKRLWINSLEKDVIRSGFQNLQPGMNYY
                     PFYQEAQTRQIADWLIGMNASPLYTLNLQQKGVQGTFSLGRVQTPTLYLIFQRQEAIE
                     NFKKEPFFEVEASIKVNQGSFKGVLSPTQRFKTQEELLAFVSSKQAKIGNQEGIIADV
                     QTKEKKTNSPSLFSLSSLQSKVNQLYKATA"
BASE COUNT         2743 a         1298 c         1555 g         2611 t
ORIGIN      
        1 ctcctggtat gttttcttct agtctacaca ccttaatttt tctgtctagt taattgtagc
       61 ctatccagag tataatcatt gtaaggtcaa gtatttgact ttttcgatta tgagagcgtt
      121 accttttcta ttactgaagc ctttataaaa tggcgaaata atagaagaaa ctgaaagctc
      181 ttaataaata gacaaactac gttccaatag acgttttaaa aagggtatga aatacagcat
      241 acaaggagtg aaaaaatgga aaaaataaat gaaagtaaag tatcggtctg caaagaaaaa
      301 ggtgagtctt attttttaga aacgttatcg ttaaaacagc aagaagataa gctgttttct
      361 gaatgggaaa aggaagagtg cttgaagggg tattatggga taaatcaaga tggactggca
      421 gatgaaagta gctatttaca atcacttccg aaaattgctt tcatcttaaa ggaagcatac
      481 gggaaagaaa attttgatat gcgcccttat tattacgatg gtgctcatgc tggaagcaaa
      541 acttggcgaa ccgccccttt atggattgct gggatatcta aaatttacga agaaaataaa
      601 agcactatag ctcaaataaa aactgaaaaa agaaatatgg gttggaaaga gttcaatcaa
      661 gaatatatac gaaaggtagc tatcctaaac ctcaacaaac aatgtacgac taatggaaag
      721 ttaacggatc ggaaatattt tcaatccggt atagataata aaaaatttat aaataaacaa
      781 atagagatat acaatccaga aattattatt tgtggaggaa ccttctatcc gttttatgat
      841 cgtatttatg attataaaaa ctttgatacc aaatatgaaa gtgccaacca aaataaacag
      901 tacgcagaag gatataagga taaaaaaggc cgattgatta taaatacttt ccatcctgga
      961 gccataaaaa aagaagagcc atggtatgac tctataatgg aaatagttga aagattcaaa
     1021 agcgaaggct tgtttgctaa gtaagtgagt tccttcttcc aaattacaaa aaataatgga
     1081 taggctacac accttaattt ttctgtctag ttaattgtag cctatccagt cgcgcacgtc
     1141 ctaagcattg cgcagttttg gtaacggatt gattattttt gaaataagac tctatgacta
     1201 ctagttcgtc tgttgtaaga tgggtgtagg tcatttgtac tcactcctta ataattcttt
     1261 ggtcggaact attttgagtg tagcacaaat gatcttttta gttgtctagc ttaattttac
     1321 aatcgacgtt gtaaaaatta tatatgatta tgtaaaaaag aataaaataa ctaaaaaatt
     1381 taactgataa aaaaattgta atgacaaaag aacggatctt ttatagatcc gctctttttg
     1441 atgagatagt aatatttaaa gtaatataaa tagtaatatt atggtaatac acatagtaat
     1501 atatatcgta atattgtggt aatacaaata gtgatataaa aatttcgccc tataaaaaaa
     1561 gaaatagcga taagctactt cttttcataa ttatcgaagt taagtggata cttactatag
     1621 ctgtttagat gtttttgaac ttcttcttca gtggcaagtc ccagctgtaa taaatgttgc
     1681 caaattgcat tgtccataaa atctgaaata aatcccttag tcccaggaat ttttttagaa
     1741 tgtctttggt ctttgtacac taaactttca actcgctgta tagtttcttt tttatattta
     1801 aatgtacgtg caactagttc agaacttgta gatttcgaag ttttgcttaa gccaaatctg
     1861 tttgcttcat taaagttttc ggtaattgtt tctttatctg agggaaaact attgctaaca
     1921 gttacctcag tctcaggtat gctatcgata gtgtcattag gtgtttctag ttcttccagc
     1981 tcctcatcga atacagactc aaaatctcct gttggttttt ttctgtttat tcttggcatt
     2041 attcttcacc gtcactttca acatataact tatgaggaat ttctagttct ttaccatttt
     2101 tagaaagtaa acctaacttg ttcatttcga taatcagctt ataaaaatgc tgagcaaatt
     2161 tgttttcagg tgaactcatt gttatcggca ttccgtttcg aactaattta tcagcaaagg
     2221 taattgatct tgggagttca gaatcaaaat aatgataatt gtttctatta gtatatttca
     2281 tcattgcgtt aatcattttt gcatgtagat ttgtattata gactttgttg gcaagtacgc
     2341 ctccaatgcg taaatttgga ttgtattttt ctttcaatgt gttcacacga gatattaagt
     2401 gtgtaactcc atcaacccca tttaaatcag gttcataagg gacgataact acgtctgcaa
     2461 ttgaaagaac agatgaggta acttgtttta actctggtgg tgtatcgaaa atgatgtaat
     2521 cgtatttatc actcacatta tcaaatttac catcaagagc attaaaatag ttcgcgctgg
     2581 gatcaataat attattcatt tttttcttta atcctgaaac agtcatgatt tcagttaagt
     2641 tatccttaaa ttttttaagt aaagatacaa accattctaa tatggtatca cgaaattgtt
     2701 ccattttatc aaactctaaa tagttgttat cagaattcgc aggaagaacg tctatatgat
     2761 cgtcatatgt ttgaacaata gtttcttcaa ctgttgcatt atccatgaag acatcataaa
     2821 tcgtattttg atccttagct actttcacac gaaaagactt tgtactattt ccttgagcgt
     2881 cagtatcaac gacaagaatt tttgcttcag gaaaactcct acggatagct cctgcgagat
     2941 tgattgtaat aagagtttta ccaacaccac ccttgtttgc tgcaacagtc aaaactactg
     3001 ccatttttca attcctccct aaataatata atagtaatat ttttggtaat agataagtaa
     3061 tatagataat aatatataaa gtaatatttt gttaatcgta acaatacgag aaagtaatat
     3121 actatattac tttctcatat tagcataata cgttgtcgaa atcaacaata aatcaaaaaa
     3181 taaaacagca gattttatat tatgttacta ttgataatag taacataata gtaagataat
     3241 atattatatt actattatgt taccttttaa acactgatag atagggaatt tgaagaatta
     3301 tattaaaaaa aggattgtat ataaattttt ttgatggtaa tattataaac gaggatgttg
     3361 ctataattaa caacgaagag gtaagatttc atgaaaaaaa actctaaaga gtttagaaac
     3421 gaatatgaca gattcgttct taagtttttg attgataatt attatataag ccgaattgat
     3481 ctatctaaag ctattggatt agctcctagt tatgtgcgag aattttataa tggatctcgt
     3541 agctttggaa atgaggcatt agaaaaacta gaatcaacaa tttttaactt atataaacct
     3601 ttgctagaga atcattcatt tgaattaaat caagtacagg aaatgataga atcaattgat
     3661 tctgaagagg aacttgagtt gttcagactt aagggagcta acgtattaga catttagata
     3721 atttctactt gatttggtaa attatattta caactttcaa cagattcggt aagataaaaa
     3781 aaatatataa aaaagagacg gataaacaag tgaattggac ctcactcatt tatctgaatc
     3841 acataaagca actatgtgtt ctcgctcgtc tcaaggaaat tatgtaagtg gtagccaacc
     3901 acttatgtga tttgaataaa tctgttcgga ctaccaatcc gaacctgtag gtttatttta
     3961 ccatttttag acgggcaact caatagataa acgcttattt gtcatgcttt ctttagattg
     4021 ttttgatatt tctagcgatt gagagaacac agatcgaacg attatttgtg ttctcttttt
     4081 gtttagaaag gataagtagg catgacagct tctttagacg tcgtttattc aacgatctta
     4141 caaaatggta tccgtaaatt taaatataaa aatagccgcc ttaaaccggt ctcttttagc
     4201 gaacagacgg ggaaaggggc tatttttgcg taccgttcaa aagagcatat ggttgaggga
     4261 ataggcttag tgatcacgtc tgaagagggc attatcgaga ataacaatgc gtttagtcac
     4321 tggaccccaa acgtcttccg ctatggcacg tatactgatg aaggcagaat gtttacaaaa
     4381 gggcattctg aggacaattt acggcaaatc aacactttct ttgttgattt tgacacctta
     4441 gacccaaatt ttgattatgg agagattttg ttggcaagcc atgagctagg atttatgcca
     4501 acaatggttt tgcggactcc ccatggttac caagcgtttt atgtactgga tcagccagct
     4561 tttgtgacaa agaaatccaa ttttaaagtg atcaatgtgg ccaaaatgat ttctaacaac
     4621 ttgcgaaaga cattagccaa agattttcct gtagacgtca atgccaatca ttttggaatc
     4681 actcgtatgc caaatgaaga caatacctta ttctttgagc cccaatatcg ttatagcttt
     4741 gcggactgga tcaactggtc aatgcgtgtc gatgcggata aagcagtaac ctacagaaac
     4801 gtttttgaat taccgtcaaa tcaggatttt cgccaagtgg acgaaccctg gttccgtcta
     4861 ttgatgcgta gtgaaaagat taagggagag aagggaagat atggtcgaaa taacgtcata
     4921 tttaccctgt ctttagcata cttttcttcc ggatacgaaa tcgaagagtg cgagttggcc
     4981 atgttagagt tcaacgatcg attagcctat cctcttactg atcgggaact gacacgaatt
     5041 atccgatcgg cttattcagg aaagtaccag gcagcgcaca gagaaaaaat tattctatta
     5101 tgccaggaat ggatcgatga aaatttatct gaagaacagc tgtttaataa gaaaaaaggc
     5161 tggtggaaat tcaaaaaaga gcgtaaagtg cgcaagtatt cgcacagcca tgagtgggcg
     5221 caagatctct tagcttattt gaaccaacaa tcatacactt ataaacctta tatcgtttca
     5281 accaagaaag agttaagaga agagcttaaa attcctgaac gctccttgga taaagtattg
     5341 aaacagctga aaaatgaaaa taagatctac tatcgtgttc gttccggtcg caatgggggg
     5401 ataactttgg cgtcagtgca tggcttgatg cgatcgatca ttcgagtgaa gaaggaagtc
     5461 caagaggcgt attttagtgc tatttcagag gtttttggat tggcacgtac atttatctac
     5521 tcaacgctgg aacaactcat agaggcacct aaaaaggctg aacaaatgga attgtttgaa
     5581 gtggataccg gataaaaata aaacccgcaa attgcctttt acattatatc tttgatacgc
     5641 tctccgagtc agaggtttta caggtcttag ggaattccct tgattgcaat gtttggataa
     5701 gtgaggtact attatcgcat atgtgattat atttcttagg gggttaccgt ccatgggagt
     5761 gaatactttt gtttatcctt atcccgtcag tgttttcatt atccagcgtt taggtatgac
     5821 tgtggaggaa ttttgtgagt tacatggtta taggcaaagt accgtagcaa cttgggctta
     5881 tcggaatagg cctgtaaaag tcttaccctg tgattttctg tattgtttga gcttggcttc
     5941 tggtttgtca atggataagg tttatcagga tttattactg ttggaggaga aatttttaca
     6001 aagtttggat cctaaaaagg agaaaaaatc gatttaaagt ttagtaagtt tgaaaggaag
     6061 agggggataa taatgtttcg tgtagaaatt gttgaaaaga aaacgattga aaaattggaa
     6121 aaagcagtga ataatattct tattagtaaa ggggataaag tacagactat agaatatgct
     6181 gcagtaaaaa agatttaaac gtctattatt ctgctatgat tgtatataag gcttgaggat
     6241 gttttgagtt gttaggaatc taagggaagt aaaaatattt ctataggaga acagaaaaga
     6301 tggataatga tcattgtgag aatgtaaaca agttagaaag tgcgggtaaa acttattata
     6361 ttattggtgc ggttctgttg caaagttcca aaatgaacaa tactagtcta acactagcta
     6421 tagtttatgc aggtattcct aataatatct tcatttccgt gcagactgaa aacccgaaga
     6481 gagtgccttc ttttcggttc ttcttatata atcctcgaat ggcttccatg cctttaatcg
     6541 tggttgaggc tgttcgtaag cttcgataaa atttgtttcg tctcttgatg ggacgatgat
     6601 cttgttcaat gaggttattt agatatttca ccgtgcgatg ttctgttcgc tggtaaaacc
     6661 cgtgtgcctg taattttttg aaggcactgg caatagaggg agctttatcg gtcaccagaa
     6721 cccttggttc atcgaactgt ttaactaatc tcttgagaaa ggcgtaagct gcttgtgtat
     6781 ctcgcttttt ccgtaaccat atatccagag tgagaccatc tgcatcaatg gcgcgataaa
     6841 gataatgcca ttttcctttg attttaatat aggtctcgtc cattttccac gaataaatgg
     6901 actgtttgtt tttcctcttc caaatgttgt aaagtagttt cccatattcc tgtacccaac
     6961 gatagacagt ggtgtgagac acgttaatac cacggttgta cagaatttct tggacgtcac
     7021 gataactcag gttgtaccga agatagtagc ctacagcgac aataatcaca tctttctgaa
     7081 attgtttgcc tttaaaatgg ttcatcttcg ttactcctcc tagttcctat taaactcagt
     7141 ttaccctata atggatctga ggggaaactt tgcaacagaa ccagttgaag aacaaactgg
     7201 aatcaatcgc cgaacgttta gaaggtatcg agcaagatat aacgtgacag tagatcaaag
     7261 aaaaaacaat gaaaagaggg atagttaatg atgagtacgg ttattttagc tgaaaaacca
     7321 agccaggcat tagcctacgc aagtgcttta aaacaaagca ccaaaaaaga cggttatttt
     7381 gagatcaaag acccactatt tacagatgaa acgtttatca cctttggttt tgggcattta
     7441 gtggaattag cagaaccagg tcattatgac gaaaagtggc aaaattggaa acttgaatct
     7501 ttgccgattt ttcctgatcg atacgatttt gaagttgcaa aagataaggg aaagcagttt
     7561 aaaattgttg cagaacttct caaaaaggca aatacaatta ttgttgcaac agatagcgac
     7621 agagaaggtg aaaatatcgc ctggtcgatt atccataaag caaatgcctt ttcaaaagat
     7681 aaaacattta aaagactatg gatcaatagc ttagaaaaag atgtaatccg aagcggtttt
     7741 caaaatttgc aacctggaat gaattactat cccttttatc aagaagcgca aacacgccaa
     7801 attgccgatt ggttgatcgg catgaacgca agccctttgt atacgttaaa tttacaacag
     7861 aagggcgtac aaggtacatt ttcactagga cgtgttcaaa cgcccacctt ataccttatt
     7921 tttcagcgcc aggaagccat agagaatttt aaaaaagaac cttttttcga ggtggaagct
     7981 agtataaaag taaaccaagg gtcgtttaag ggcgttctaa gccccacaca gcgttttaaa
     8041 acccaagagg agcttttagc ttttgtttct tctaaacaag ctaaaatagg caatcaagag
     8101 gggataattg ctgatgttca aaccaaagag aagaaaacga atagtccgag tttgttttct
     8161 ttaagtagtt tgcaatcaaa agtcaatcag ctttataaag cgacagc
//
LOCUS       DAXQKX010000092         8198 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.095, whole genome shotgun sequence.
ACCESSION   DAXQKX010000092 DAXQKX010000000
VERSION     DAXQKX010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8198)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8198)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8198
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.095"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            593..1165
                     /locus_tag="ACF3MF_002583"
     CDS             593..1165
                     /locus_tag="ACF3MF_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003706982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HFE3928487.1"
                     /translation="MTENKATQERTPQERLQEEQEHKEHVHHTKINAAAIADHLLGNM
                     HTLHVKLHQYHWYVKGANFFTLHEKFEELYNENEKWFDKLAERLITSGHKPASTTVEF
                     EKYSMLSEDAVNKYAKAEDMVENIIEDFRSTRDLTIRAIRLAQDEGDDALEDTLIAFK
                     NDLDKNIWMLQAFIGKEALEDDDALDEDED"
     gene            1310..2014
                     /locus_tag="ACF3MF_002584"
     CDS             1310..2014
                     /locus_tag="ACF3MF_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011476586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFE3928488.1"
                     /translation="MTKHTHHEIGDHAACIRLVPIFNHLEDSAMNYIAEKAHTKQYQK
                     GEFLFRSQEKEDTLYIINRGKIRIYRLADSGKEQLVRILNPGDFTGEWTLFNPDAVHE
                     EYAEATRDTVVCMIQQKDVQDFLEQYPAISLKLLAEMSKRLESSERQTTQVAVESVIT
                     RLVLFLAENVEPEMGNSPTITLPMAKKDIASYLGTTPETISRKFGELEDEGLIQQLSG
                     KRIKIQDLDDLLLYSE"
     gene            2038..2331
                     /locus_tag="ACF3MF_002585"
     CDS             2038..2331
                     /locus_tag="ACF3MF_002585"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0042158 - lipoprotein biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase family
                     protein"
                     /protein_id="HFE3928489.1"
                     /translation="MVFCRSLLTTGQNSVLLRQGEVALSYVLWYSVGRFFIEGMRTDS
                     LWIGEWIRVSQALSLALFIGAIVVWFIRRQDYPPISYYSDGNKGQKKTIKMVN"
     gene            2478..2711
                     /locus_tag="ACF3MF_002586"
     CDS             2478..2711
                     /locus_tag="ACF3MF_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003106687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HFE3928490.1"
                     /translation="MEKAILQLETLSCPSCMQKIEGAVKSVNGVDKDSIKVLFNSSKV
                     KANFDSAVTSIEEIQKAIENVGYPVLKAKVKAA"
     gene            2909..4813
                     /locus_tag="ACF3MF_002587"
     CDS             2909..4813
                     /locus_tag="ACF3MF_002587"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFE3928491.1"
                     /translation="MQQYILSKKNVITVISGLLIVLGFFSHFVLENVGLSEWSLIIAS
                     VFGITPIAIQAFQAMKVKVISIDVLVSIAAIGALFIQNYEESAIVTFLFLFGHYLEQR
                     TLNQTRSAIKELTEMAPESALKQMDNGEFEEVEVDDIDEGDILLVKTGAKVPVDGIVL
                     TGEGHINEASITGEAVPVNKLADAEVFAGTILENGTIQIRADRVGEDTTFGKIIELVE
                     EAQDSKSEAERFIDRFSKYYTPAVLVLAIVVWAFSQNIELAITILVLGCPGALVIGVP
                     VSNVAGIGNGARNGVLLKGSEVIQDFSNVDTIVFDKTGTLTVGNPTVAATELYEKDPA
                     ETLGYLASVERESDHPLAKAVLNQIGETNFYPVEGTEVVKGGGIVSSVAGHRVAVGNV
                     ALMEKENVTLSKKVQKDIKRFEQHGNSLVLTAVDGELKVLMGIRDQVRPGVKANLQEL
                     KDLGVKNLVVLSGDNQGTVDVVAGELGLTEAHGHMLPEDKSAYIGKLQQRGQIVAFVG
                     DGVNDSPSLALADIGIAMGSGTDVAIETSDVVLMNSNFSNLPHALGLVKATANNMKQN
                     IVISIGVVLVLLTSVFFSEWMNMSIGMLVHEGSILVVIFNGMRLMKYKLKGRKEQKEV
                     SAPAEKVKIS"
     gene            5123..5485
                     /locus_tag="ACF3MF_002588"
     CDS             5123..5485
                     /locus_tag="ACF3MF_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR/SmtB family transcription factor"
                     /protein_id="HFE3928492.1"
                     /translation="MEKVCQVTIVHKEKVNVIKKKLDQKDFSNLLVLGKCFSDSSRIK
                     IFYALETYKEMCVCDLAEILNASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIHVFLKLSENLSMKS"
     gene            5502..6119
                     /locus_tag="ACF3MF_002589"
     CDS             5502..6119
                     /locus_tag="ACF3MF_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HFE3928493.1"
                     /translation="MLQSIFSAIAVYISTSIDYLFILLIIFSQSHTKKGLRQIFWGQY
                     LGTGILVAVSLFAAYVLNFIPQDWIIGLLGLIPIFLGIRVALVGEEEEEEEEVVEKLE
                     SRGTNRFFWTVALITIASGGDNLGIYIPYFASLSFSEIVTALIVFAISVAVLCYISYK
                     LAKISFVSETLEKYERILVPIVFIGLGIYILIENGTIQTVLSLFN"
     gene            6359..6910
                     /locus_tag="ACF3MF_002590"
                     /pseudo
     CDS             6359..6910
                     /locus_tag="ACF3MF_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876259.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            7223..7765
                     /locus_tag="ACF3MF_002591"
     CDS             7223..7765
                     /locus_tag="ACF3MF_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBECR4 domain-containing protein"
                     /protein_id="HFE3928494.1"
                     /translation="MSIKETTQITRQLNAIYKAAHLLQEHFVDKKVSFVGEVSTVAII
                     FSTTNFMHLCGIDYRRGTHLFFQDALDRKINLQDIQIKTDGTTFQKLQVIGSLDLLLG
                     KHISIVGRGVYSSLRYDAAIRTRKKILALSLKQNGLIYIPISLLNLSSKEIGPGQKVT
                     GIFSEDLTSGELKMIMEVID"
BASE COUNT         2701 a         1374 c         1696 g         2427 t
ORIGIN      
        1 ttccaacagg ccgaaggcga gctcgaacaa atgctgagtc aaccgatgga gaattagaaa
       61 caatctacag tagggaagaa ccatttacac aaaattattg acgctcccaa gctaaaactc
      121 ctattaatcg atctactaaa aataaataaa aaaattcttt tcaattttta tttatggtat
      181 gacataaata aagtaaagtt attcttctag gttaatctta ttaatactct ttctcactag
      241 tgttgcatgc aacactagtg agaaagagta ttaaatatac tgcaaggcaa gacatttggt
      301 aattgaagaa taacaagcaa aaaaatagca gtcaggtctc ttgacaaagt atagttgcta
      361 ttcttttttt aggccctact ttaatgaaat ttttgtttgg agggaacgac ttcattcctt
      421 tgattatttc agttgaattt aatagagaag cctggcgtct attaagaaat acttttcttg
      481 atgagcgtca atttttttaa cggaaatcta tcctatacta aattcagtaa agaaaaagga
      541 ggaatcaaag aaagctattt taaacaaacc aaaattatag gaggaataaa tcatgactga
      601 aaataaagct actcaagaaa gaacacccca agaaagatta caagaagaac aagaacacaa
      661 ggaacatgtt catcatacga aaattaatgc agcggccatt gcggatcatc ttttaggcaa
      721 catgcataca ttacatgtga aactgcacca atatcactgg tatgtaaaag gagccaattt
      781 ctttacgttg catgaaaaat ttgaagagtt gtataacgaa aatgaaaaat ggttcgacaa
      841 acttgcggag cgtctaatta cttctgggca taaacctgct tcgacaacgg ttgaatttga
      901 aaaatattcg atgctttcgg aagatgcagt taataaatac gctaaagcag aagacatggt
      961 tgaaaatatt atcgaggact tcagaagcac ccgtgaccta actattcgcg cgattcgttt
     1021 agctcaagac gagggtgacg atgctttaga agatacattg attgctttta aaaatgactt
     1081 agacaagaac atttggatgc tgcaagcgtt cattggtaaa gaagcattag aagatgatga
     1141 cgctcttgat gaggatgaag attaaggtaa aagtagaagc tgatttaggg attggaattc
     1201 tttccagtcc tttttctatt ttcttgatgt gcatcaattt ttttgtagta agagacttat
     1261 ataataaaag cagcgaatat aaacaaaata aataaagggg gagaatgaat tgactaaaca
     1321 tacccatcat gaaattggcg accacgcagc ctgtatccgc ttggttccaa tattcaatca
     1381 cttagaggat agcgcgatga attacattgc tgaaaaagcc cacacgaaac agtatcaaaa
     1441 aggagagttt ctgtttcgtt cacaagaaaa agaggatact ttatatatta tcaatcgtgg
     1501 gaaaatccgt atttatcgat tggcagactc tggcaaagag cagctagtgc ggatcttgaa
     1561 ccctggtgat ttcaccggag aatggacctt gttcaacccg gatgcagtac acgaggaata
     1621 tgccgaagca acccgagata ccgttgtctg tatgattcag caaaaagatg tccaagattt
     1681 tctggaacaa tacccagcta tttctttaaa actattggcg gaaatgtcta aacggttaga
     1741 aagttcagaa cgtcaaacga cacaagtagc cgtggagagt gtcattaccc gtttagtttt
     1801 gtttttggca gaaaatgtgg aacctgaaat gggcaactct cccaccatca ccctgccgat
     1861 ggcaaaaaag gacattgctt cctatttagg aacgacacct gagaccatca gtcgcaaatt
     1921 tggagaattg gaggacgagg gattgattca acagctgtct gggaaaagga tcaagattca
     1981 ggatttagat gatttattgc tttacagcga ataatcggac acactttttt ctacacgttg
     2041 gtgttctgtc gctctttatt aacaacggga cagaactcag tgcttttgcg tcaaggagaa
     2101 gtcgctttga gttacgtttt gtggtactca gtgggtcggt tcttcattga aggtatgcga
     2161 acggacagtt tatggattgg cgagtggatc cgcgtttcgc aagccttgtc tctggccctg
     2221 tttattggcg cgattgtagt atggtttata cgcagacaag attatccacc aatttcttat
     2281 tattctgatg gcaataaggg gcagaaaaag actattaaga tggtgaattg agcaaaaaga
     2341 taaaaagaag tgcaaaactt gatatgcgtc aattttcgtt tgctaaaagg gagctatact
     2401 acagttgtaa agaggaaaag gcagtgttca ttaatctgct gccgataaaa taaaaacaca
     2461 taaaggagat aggaattatg gaaaaagcta tattgcaatt agaaacgttg tcttgtccaa
     2521 gttgtatgca aaaaattgaa ggtgccgtaa aatcagttaa cggtgttgat aaagacagca
     2581 ttaaagtatt attcaactcc agcaaagtca aagccaattt tgattcagct gtcacttcga
     2641 ttgaagagat tcaaaaagct atcgaaaacg taggctatcc ggtccttaaa gcaaaagtca
     2701 aggccgctta acagattaaa tgaactaggc aattctggaa gaaaagctat ttttccagga
     2761 ttgctttttt tgttgcaatc cgattcgagg tgcctagaaa cgataaaaga gaactttcta
     2821 aacttgatgt cagtcaatta attacttagg caattatctt atactgtgtt tatcaataaa
     2881 agagaaatta aatttggagg gaaaaagcat gcaacaatat atattaagca agaaaaatgt
     2941 tatcaccgtc atcagtggat tgttaatcgt actcggtttc ttcagtcact ttgttttaga
     3001 aaacgtagga ctttcagagt ggtctttgat catcgcctct gtctttggga ttacgccaat
     3061 tgccattcaa gcgtttcaag caatgaaagt caaagtcatc agtattgatg tcttagtcag
     3121 tattgcagcg attggtgcgc tttttattca aaattatgaa gaatcggcta ttgtcacgtt
     3181 cttattctta ttcggacact acttggaaca acgaacattg aaccaaacgc gatctgctat
     3241 caaagaattg actgaaatgg cacccgaaag cgccttgaaa caaatggata atggcgaatt
     3301 tgaagaagta gaagtggatg atatagatga aggggatatc ttgctcgtta aaacgggtgc
     3361 gaaagttcca gtagatggca tagtccttac gggtgaaggg catatcaatg aagctagcat
     3421 tacaggtgaa gctgttccag tcaacaagct agctgatgca gaagtttttg caggaaccat
     3481 tttagaaaac ggaacgattc aaatcagagc tgaccgagtt ggtgaggaca ccacatttgg
     3541 aaaaattatt gaactcgtgg aagaagcaca agattctaaa tccgaagcgg aacggttcat
     3601 tgatcgcttt tctaaatact acacaccagc tgtcttggtt ctggcaattg ttgtatgggc
     3661 gttcagtcaa aatattgagt tagcaatcac catcttggtt ctaggttgcc caggcgcatt
     3721 agttatcgga gtgcctgtct caaacgttgc cggtattggg aatggtgctc gtaacggtgt
     3781 tcttttaaaa gggagtgaag tcattcaaga cttcagcaat gtggatacaa ttgtatttga
     3841 taagacaggt actttaactg tcggaaaccc aaccgttgca gcgactgaac tgtatgaaaa
     3901 agatcctgct gaaacgcttg gctatctggc cagtgtggaa cgggaatcag atcatccatt
     3961 agcaaaagcg gtcttaaatc aaattggaga aacaaacttt tatcctgttg aaggaactga
     4021 agtcgtgaaa ggcggcggaa tcgtttcaag tgtagctgga catagagtgg ctgttgggaa
     4081 tgtggccttg atggaaaaag aaaatgtcac tctcagcaaa aaggtgcaaa aagatatcaa
     4141 acggtttgaa caacatggga actctctcgt tttgacagcg gtcgacggtg aattaaaagt
     4201 actgatgggc attcgcgatc aagtccgtcc gggtgtgaaa gctaatttgc aggaattaaa
     4261 agacttgggc gtgaaaaatc tagtcgttct ttcaggagat aaccaaggaa ccgttgatgt
     4321 ggtcgccggc gaacttggtt tgaccgaagc tcacggccac atgttgccgg aagacaaatc
     4381 ggcttatatc ggaaaacttc aacaacgtgg tcaaattgta gcctttgttg gagatggcgt
     4441 taacgatagt ccgtccttag ctttagcaga cattggaatc gcaatgggaa gcggaacgga
     4501 cgtagcgatt gaaacatccg atgtcgtttt aatgaactcg aacttcagca acttgcctca
     4561 cgcattagga ttagtaaaag ccaccgcaaa taatatgaaa caaaatatcg tgatttcaat
     4621 tggagtagtg ttggtcttgt tgaccagcgt cttcttcagc gaatggatga atatgtctat
     4681 cggaatgttg gttcatgaag gtagtatctt ggtggtaatt ttcaatggca tgagattaat
     4741 gaagtataag ttgaaaggtc gaaaagaaca aaaagaagta tcagcacctg cagagaaagt
     4801 aaaaatatct taagaataaa ttagaagagg ctgagacaat agtccatcct tgaaatgaca
     4861 aaagcggaaa ctcagatttt taaatctggg attttccgct tttttgagtt cttgaaaaaa
     4921 aataagagta tagagtatgt tctttataaa attaattttc gtgtaaatga ttaaaaaatt
     4981 taataataaa atttaaattc ctattaagtt gtaacacatg aaattgctta taatagtgta
     5041 ttgaaattaa ggtagattga caaacgagtg atcaaataga tatactacct tcaaacgacc
     5101 gtttgaatgt gaggtgagat gaatggaaaa agtttgccaa gtgactatcg tacataaaga
     5161 aaaagtaaat gtaataaaaa aaaaattgga tcaaaaagat ttttcaaact tacttgtgtt
     5221 agggaaatgt ttcagcgatt cttctagaat taaaattttt tatgctttag aaacctataa
     5281 ggaaatgtgt gtctgtgatt tagcagaaat acttaatgct agtgtcgcta caacgtcaca
     5341 ccatttacgt tttttaaaaa aacatggaat ggcaaaatca cgtcaagatg gaaaagtagt
     5401 ttattactct ttagcgaatg aagacatcct ttccgctatt catgtttttt taaagttatc
     5461 agaaaatcta tctatgaaat cttagtttgg aggaagttat tttgttacaa agtatttttt
     5521 cagctatcgc tgtttatatt tctaccagca ttgattattt gtttatcttg ctgattattt
     5581 tttctcaaag tcatacaaaa aaagggctcc gtcagatttt ttggggtcaa tatctaggaa
     5641 caggtatctt agtagccgta agtttatttg cagcatatgt gctgaatttc attccgcaag
     5701 attggatcat tgggcttctc ggtctaattc cgattttctt aggaatcaga gtggcattgg
     5761 ttggcgaaga ggaggaagaa gaagaggaag tcgttgaaaa gcttgaatca agaggaacaa
     5821 accgcttctt ttggaccgtt gccttaataa caattgcttc tggtggcgat aacttaggga
     5881 tttatattcc ttactttgcc tcgttatctt tttcagagat tgtcaccgct ctaatcgtat
     5941 ttgctatttc tgttgcggtt ctttgctata tcagttacaa attagccaag atttcttttg
     6001 tttccgaaac cttagaaaaa tatgaacgaa tccttgttcc tatagtgttt attggcttag
     6061 gaatttatat attgatcgaa aatggtacga ttcaaactgt attgagttta tttaattaat
     6121 aaatagtttg attgttagta caaaaaaaga cagcgattaa aactcgttgt cttttttttg
     6181 tactaacaga ttggcgcatt atctaagtaa tataattcga tacatgaaat tacataaaat
     6241 catgtatcaa gaatcctatc cttatagggt tctttttttt tactccccct aaacacacga
     6301 tttcgtgttg taataactat aatcatgtat tcgaacagac taaaaaggag ggattgtcat
     6361 gggctataat gttcagccac tacggtcgca acaggagatt aatgattttt tattttgcct
     6421 gcgacggaat aaaaatgcgg aacgtgacgt tttcttgttt ctaattggaa ttaacagcgg
     6481 tctgcgcatg tccgacatcg ttaaactcaa gaaaaaagac gtgattacct caaaaaaccc
     6541 gcgcatcgtg gagcaaaaga cagggaaaac acgcatttta tacttaagca gcttacagga
     6601 cttgattcac ggctaaaccg cacccttaga tccggaggct tacttgtttc ccagtactaa
     6661 gggcggccat ttagaagtca atacggtcta ccagatgttt caaaaggtcg cgaagctgtt
     6721 aggaagggac gatatcggca cccacaccct acgaaaaacc tttggttacc actattacaa
     6781 gaaaaccaaa gacgtggcca ccttaatgga aatctttggt cacagcagcg agaagattac
     6841 caaacgctac atcggaatta atgaagatga aatcagtgaa acgttattaa attttcggtt
     6901 aggtttttga ttgtattata taatagataa gcacagtaag acggttataa tcacccacag
     6961 tattggacaa atcaaccttt ttttggtata ttatatatac aaatgagagc aggctcatag
     7021 tcaacttgat ataaatccgg aacataaggg tccggcgggt ggcgagcacc aaaactaaac
     7081 tcgatacaaa tccggaacgt aagggtccgg cgggtggcaa gcaccaaaac taaacctgta
     7141 caaaaggctg ctcttttgag cagctttttt tattgggaaa aaggagcatt cttcgcacgc
     7201 ggcaaaaaaa gaatacaaac gcatgtctat aaaagagaca acccaaatta ccagacagtt
     7261 aaacgcgatt tataaggctg ctcatctctt acaagaacat tttgtagata aaaaagtatc
     7321 ctttgtcgga gaagtctcaa cggtagcaat tattttttcg acaactaatt ttatgcacct
     7381 ctgtggcatt gattatcgca gaggcacaca cttgtttttt caagatgcct tagacaggaa
     7441 aataaattta caggatattc aaatcaaaac ggatgggacg acctttcaga aattacaagt
     7501 aataggtagc cttgatttat tattggggaa gcatatttct attgttggca gaggtgttta
     7561 ctcttctctt cgctatgatg cagctattcg aacaaggaaa aaaatattgg ctctgtcttt
     7621 gaaacaaaac ggattaatct atatccctat ctctttgtta aacctatcat caaaggaaat
     7681 tggacctgga caaaaagtta ctggcatttt tagcgaggat ttaacatccg gggaacttaa
     7741 aatgattatg gaagtcatcg attaatcatt aatagtgata tgcgacgtca ttttgaagta
     7801 attattctat tttgggttat aaaataaagc attttaagac gatttcaaat cattcatgtg
     7861 ggttatttat cacggatgag cttgaaatcg ccttttatac gtatcaaatt gaaatgttcg
     7921 gcatacaatc tatcgttgtt actacattac taattgtcac ttgttaagga acttggatcc
     7981 tttctaaaca ttccctagag ataaatttta ctttatccct ccgttaatat ccaatttaag
     8041 cacctttccg attcagggtt aatttgcata tcaagtgcag cttgtgttct agtaagatta
     8101 gcccttttag tccggctgag ttgacttatg gatataagat atggtcatag caaatagata
     8161 ctacgtatag tctgttaatt tagtgtcatt aatcttaa
//
LOCUS       DAXQKX010000093         7626 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.096, whole genome shotgun sequence.
ACCESSION   DAXQKX010000093 DAXQKX010000000
VERSION     DAXQKX010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7626)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7626)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7626
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.096"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(710..1750)
                     /locus_tag="ACF3MF_002592"
     CDS             complement(710..1750)
                     /locus_tag="ACF3MF_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HFE3928495.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDSTVIAKIANTAKPRKINDST
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMQEDSINTFVPENVLNLIKTFSSSYSEAQQTVQTIHNAKKKAEELEQTIVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(2099..2425)
                     /locus_tag="ACF3MF_002593"
     CDS             complement(2099..2425)
                     /locus_tag="ACF3MF_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928496.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNYKPKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(2412..3200)
                     /locus_tag="ACF3MF_002594"
     CDS             complement(2412..3200)
                     /locus_tag="ACF3MF_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFE3928497.1"
                     /translation="MARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVDIDPQG
                     NATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAEREFTQVG
                     SEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLKGLIKL
                     SETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTTAATEISRVIGAKIFKTYIRRT
                     ITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(3568..3858)
                     /locus_tag="ACF3MF_002595"
     CDS             complement(3568..3858)
                     /locus_tag="ACF3MF_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HFE3928498.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(3994..4173)
                     /locus_tag="ACF3MF_002596"
     CDS             complement(3994..4173)
                     /locus_tag="ACF3MF_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928499.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            complement(4170..4520)
                     /locus_tag="ACF3MF_002597"
     CDS             complement(4170..4520)
                     /locus_tag="ACF3MF_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928500.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIVGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(4513..5838)
                     /locus_tag="ACF3MF_002598"
     CDS             complement(4513..5838)
                     /locus_tag="ACF3MF_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HFE3928501.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRS
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTKSLNLFTTEETRSQRRKKLAQMIQERIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFIAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGILSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLNIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQINEEN
                     LDKIIDKIRQKYGFTSIVHASSMLESARSITRSTLVGGHAGGNGGIKND"
     gene            complement(6209..6793)
                     /locus_tag="ACF3MF_002599"
     CDS             complement(6209..6793)
                     /locus_tag="ACF3MF_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFE3928502.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
     gene            complement(7004..7207)
                     /locus_tag="ACF3MF_002600"
     CDS             complement(7004..7207)
                     /locus_tag="ACF3MF_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928503.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            complement(7217..7624)
                     /locus_tag="ACF3MF_002601"
     CDS             complement(7217..7624)
                     /locus_tag="ACF3MF_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928504.1"
                     /translation="MLSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELTPLDRN
                     GIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSRNWKEK
                     RNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
BASE COUNT         2328 a         1376 c         1108 g         2814 t
ORIGIN      
        1 ctaatttcag cgttcgtcat acggcaaaga gccacacgga catttttata acattatgct
       61 taggcataga ttcatcgtaa tatcacgtat ttttaacctt aacacagcca aaaaaagtgg
      121 tatcactttt gaatatctgt tatactaaat ccgttacggg taataccgta acactgaaag
      181 gtaaacgcat taagggagtg atcttaatgc cacctgtgga cgtcgacgaa ggttaccagc
      241 cttccgagtc tcacagggcc tttctttttt ttgtattttc aattgtccaa atttatcgtc
      301 caaaagtgca gaacgaaaat caattcatca caagcatagc agacaattaa atttaaaaca
      361 actaaaaata tacaaaaaag tgtaattgaa tattagcagc actgcctgaa aagaagtaat
      421 atcaggcttt tcagcttggg gaaataagtg aattacctct cttcatgaat tattataact
      481 caaaaaagca catatgcaaa cactagttcc ctattttttt gagtgaaaaa taactaaaat
      541 atctaacgat tatgaattta aaacctacga ttgtgattgt tttcataaac ttttaatcta
      601 aaaactccgg aatactaact atttatttgt aatatttgta ataaaattaa aatcataaaa
      661 aagttctaat ttaaaattga tcatttttat agtaattgct ttttatcaac tactctaacc
      721 aattttccgt actaactgtt ggtaattcgt taaatgtttc tctttgttcg tttgcaagct
      781 ttgccgcaat agctttttcg acaaaccaat tttttacata aacgaaaatt agattctgca
      841 aattgtttac tttttcagtt ttttgttttt gataagcttt cagtaaagtc atatataatc
      901 ctttgtcagc atcaattcca taagattcca gttcttcata aacgacaata gtttgctcta
      961 attcttcagc ttttttcttt gcattatgaa tagtttggac ggtttgttga gcttcactgt
     1021 aacttgaaga aaatgttttt atcaagttta atacattttc tggtacaaat gtatttatac
     1081 tgtcctcttg catgatgtcg acgaagttat ctagcaaaac ttgattttgt aactggtcag
     1141 tttcagtgtc tattatgtgt ctattagtgt ctatagaatt agaatagaat agattgtctg
     1201 cgattttcgc aattacggtt gagtccttga tatgactgga ttttgccgta tttgcgattt
     1261 tcgcaattac ggtagaatca ttgatttttc gcggttttgc cgtatttgcg attttcgcaa
     1321 ttacggtgga atcagtattg tcttcctctt ccatgatttt aaagacgtct tgattcgtaa
     1381 cttctggctt gcctaagtac aataaattag gcatagattc aatcttacca tcacgtttat
     1441 ttactcttcc tctcttctgt ttcagaagac ctgctttttc taattctttt ttgatcttag
     1501 atactttacc ttcgcggcat tgtaacaatt tcattaattc ttcaactgtg aatatgaaga
     1561 atatattatc atcagaatct acccagttat ttttgactga ataatcaaat cgatctttaa
     1621 gtagcatata agcaattttt gcatcatttg aaagatccat gtatttttcg ttagtaaaaa
     1681 ataccttagg catttgataa tatttttcac gataaatttc ttttgatttg taataattaa
     1741 aatcattcat agccaatcct ctttctgtag gatagcgttt tgttcaaaac tatgttacaa
     1801 tgaattaaac aaatatatct atccactata tatttttcta ctgctgataa gtcgccaaac
     1861 tttgttaaag cagtagtctt tttttatctt tttttagttt accttaaaaa ataaattaaa
     1921 gcaaaccgct ctatttcagg gtttaagctc atggtaacta tatcacgata ttacaataac
     1981 attatatcac gatatcgtaa tattacaata tgaagataag cgacttatca gctttgatac
     2041 tactgatttt tataaaaaaa atatcacgat attatgatat cgtgatattg aatgtaaatt
     2101 aaattttatt ttgtttcttt gctagtttat atccttcaat caagtattct tcaggtatgg
     2161 attttaatag cgcatcttct ataacgtctg gtttactttt gtctgattca gcaatagtcg
     2221 tccaatattt gagtgctgac attagaattg gatttatacg aatgctatct gctgttctta
     2281 cactacttcc ttgatctttt atgactttac ttatattttt cttggttaat tcgatttctt
     2341 ctacttcttt tggtttgtag ttctttttat ttttatttcc tagtagtcta cttactgcag
     2401 cttgactgcg attatcttct gccatcaaaa tcaccaactt cttttaaata ttcttctgta
     2461 aatgctttat agtcatcttc agctgttgag ggtttattaa aattgattag atctgatcca
     2521 gcagcttgcg cttcgtcaac ggttattgtt ctacgaatat aagttttgaa aatttttgca
     2581 ccaatgactc tagaaatttc ggttgctgca gtcgtcattt ctttagaaat gttataacgc
     2641 ttattatact tagtaaatag gactcctcgt acttcaagct tgtcgttcgt atattctttt
     2701 accgtttcaa tagtttcact taactttatt agtcctttta atgagaaata cgcagcttca
     2761 actggaatga taatttcatc agaaacagta aatgcgttga ctgtaagcat tcctaaactt
     2821 ggtggacaat caattataat ataatcatag ttgtccttga ttggttgaag tactctttta
     2881 agcctgtgtt cacttcctac ttgagtaaat tccctctctg cagaagaaag ggctatgtcg
     2941 gctggcaaaa catcaattcc tttatagtcc agaatagcat ctgtaatgtc agcctcccct
     3001 tttaatactt cataaattgt aggttggttt gttccatcta tatcgaaacc tacattatct
     3061 gtagcatttc cctgaggatc aatgtccact aaaagtacat ttttaccgta aacaaatttc
     3121 aaacatgctg ctaaattaac gctagtcgta gttttagaaa ctccaccttt ttgattggct
     3181 actgacaata ttcttgccat taaaatatcc cccattcatc ttatattata atataattat
     3241 atcataatat tgtgatattg caatatcgta tatgcattat attgtaatat tgtgtgatta
     3301 ttttgtttta aagatatata tcggttcgga tataaagatt attcatatgt tattcgaaag
     3361 taaaataatc actttttatt actttaaaat tttttattaa tcataagaaa tatgttttgc
     3421 gagcagcaac tagaataatt taaacattat taaactgtct atattgttac taataattcc
     3481 cttcttatag tgcattttct tagaaaaaaa caatattacg atatcatgat attaagatat
     3541 cgtaatatta tacaattgtg attgatatta tatatgtttt tttatttttt tatcatgttt
     3601 aatcttgaag gaatcatatt ctttttctaa agacaggagc ttttcataaa catcagacat
     3661 gtttaaacta gaggccaggc ttaaatcata aacgaatgaa gcaggtaatg attttattct
     3721 acgttgtcgg gttatccagc ttgcaaccgt tccttgtggg taggcatata actcacaaaa
     3781 ttgttctaca gtgattccta aattcttgat aatgtaaaca ttgatcgggt gcgagtaaac
     3841 aaatgtattg atagacatgg tgcgtaagcc tactttcttt tattattgcg tttgcaataa
     3901 tagtttaaca cacgcattat tctagtatct actcctattt gtaaaaacaa aaaaggattc
     3961 atagagataa ctctatagaa tccgtaaaat accttatata tataacggga aaatataaaa
     4021 cctaaaatta tgataacctg ctgcagcttc tacatagaaa gagaagcgct caacaccaac
     4081 ctcatttatc aaacgttggc cataacccca aatctcttct gatagctgat caaaggttat
     4141 atactttagc tcatattgct ggataatgtt cattctaatc gactccattt attatcctgg
     4201 taaaattcga tatgacgtat ttcgtcgtag tgaattttgt cttttccaac gtagatcccc
     4261 agctcatcac tacctaagat cttgccaaca atatcttctg gatagtatcc ttcagcgttt
     4321 cgttcttctt tttgaataga tactgatcta ttttttatga ctgcagcgtt caatacttcc
     4381 gcaatctctt cagtcgtcat ttgttctttt gctaaatttt gactggttcg ttgttcattg
     4441 tcggcatcaa tttcttcagt atgatcagat aaataaaacc ctgcccactt taaacgtcca
     4501 cgatcattgt aatcaatcat ttttaattcc cccatttccg cccgcatgac caccaacaag
     4561 tgtgcttcta gtaatgcttc tagcgctttc taacattgaa gaagcatgta caatcgacgt
     4621 aaaaccatat ttttgccgaa tcttgtcaat aattttatct aaattttctt cgttaatttg
     4681 cttttgtgga tcactaaata aatccagctg aagcgaatcg gtgtacacaa gcttgctata
     4741 ggttattcca acgtgcctta cttcttgtcc ttcataatac ttatcaaaca agaaaagaca
     4801 ataattctgc aattcctttg tattatctgt gataggtatt ttcatctggt gtgaaaatcc
     4861 tggtctcgtt tctaagatcg acgtaccaat gtttaaatga acacatcctg ttttacaatt
     4921 atgctgcctg atacgaatgg ctacttgttc cgccatttct tttaccacca gctcgatttc
     4981 atttcttcta gtataatctc gtggtaacac ttgtgaatta ccataagatt tttcctttgt
     5041 cggttctggc gggattgcta tatctgttcg atcgattccg ttagcatgga agtacagctg
     5101 taatccaatc acacctaatc tattcttaat cgtataagga ttccagttag caaggtctct
     5161 aatgctcaaa attcccattt ggttgagcct ttttttcatt cgagaaccaa ttccccaaaa
     5221 gtccgtcatt tcgggaatat tccatacttt ctcaggaacg ttttcgtacg tccattccgc
     5281 aataaatcct tcattatgct ttgcttcatt gtctaaggct aatttagcca aaaggggatt
     5341 atcgccgacg cctaccgtag caatcaaacc taactcttct ttaatacgtt cttggatcat
     5401 ttgagcgagc ttcttccttc gctgacttcg tgtttcttca gtcgtaaaaa gattcagtga
     5461 ttttgtcact tttaaaatcg attcatcgat cgagtaaatc agtagatctt catcagccac
     5521 atatcttctg aaaatattat ttacctgcat atttcgcttg atatataggt tcatacgtgg
     5581 tggaacaacg tgtagtgttt taggaaatgg ttgtggtaag tcacgtggtc tactcacatt
     5641 tgtaatacca taccgctttt ttgcttcagg agaagaagct aatatcaatc ctgaaccagt
     5701 attatcagat cgactcataa caacaagttc tgttgttaat ggatctaaat ttctttctat
     5761 acattcgaca cttgcgtaaa agcttttcat atcgattaaa aagtaatcat ttactggctc
     5821 ttttgaataa tccatcataa ataacactcc attcttccac attatacaaa catatgttcg
     5881 atgttgtaaa gaagaaatag ctaaatacat aaaaaaagaa gcataggtat gctatcaccc
     5941 tgcttcttct tatgatttgt atgatcaatt tattctatca ctttactaat taatttgaaa
     6001 atctaataaa aactctcact ctaaaagagt gagagactgc aaattagagt acggactttt
     6061 ttggagttcc gttctttaat attaacaaat gaataaaatc cttacaacat ttgataataa
     6121 gttatcagta gacacttaca aaaaattctc atactattgt cacttttcta gataaatggc
     6181 aaaaattttc agcattaaat gacaaaaact aatgagaatt tgtctttcca tttttctcct
     6241 ccatttttgc caaataacga taaatggtgg ttcttgagac gttccaccgt tccgcaatag
     6301 tcttaatagg tgtaccgcta tccactaaag tcttcagtaa ttccaaatct tgttcagaca
     6361 atttttcagg acgaccacca aaccgtcctc ttgcacgagc agctgctcgt cctgctgcgg
     6421 atcgttccag gatcaaatta cgctcaaatt ctgcaaatgc cgcaaacaaa tgaaacatga
     6481 gctgtcctgt agaacttgat ttgtccatcg taatattttc ttgaatacta tgaaaactca
     6541 caccacgctc attcagtcga ttgacgattg aaatcaaatc ttccatattt ctacctaaac
     6601 gatctaagcg ccaaacgaca agtgtatcgc cagagcgaac aaaatcaatg gccatttcta
     6661 atcctggtcg attacttttt gccccactca tatgatcagt aaaaattttt tcacaaccaa
     6721 atttatttag gctgtcttct tgtaaatcca aattttgtaa accagtagat acccgggcgt
     6781 atcctatttt caaaaaaatc actccttcat taattttatt gtaacataac tttatccata
     6841 tagtttaact gaacatagat attgttatgg gtttatgaac atgaaatgaa ttgttttttt
     6901 gaaaaataaa gcaaaaaaag gaagtgtcca gaaatgggtg attttatgaa cactttcaat
     6961 tagaaaaaaa gaatgtcgac tagacactct ttttttaaaa tcattatttt tctttttgat
     7021 atgttttttg gtctcttttt tttctttttt cttcagaatc ttctagatta gaaattgatt
     7081 tttgaatttt ttgtgtctcc tgtaaagttc gctgaacttg taaagctgat tcttctttcg
     7141 gtaaattaat tttacttaga atatcgctat cttgataaaa atttggtgtg ttcacaaatt
     7201 ctggcataaa aaatccctac tttctagtta aggttcctga ataagtcgca atccaattgt
     7261 ttccagctga tttataactt tgtaaataca attttccata gtaccaataa ccatttcttt
     7321 tttctttcca attccgtgat tgaggaggtc tagaaggcca accaacttta tcaaaaatca
     7381 tcgttcctgt cactcgtatc gttttagaag ctgctcgagc aagtaatgga gaaactatta
     7441 aataattttc agtaacagtt aagtcgttag ttgggttacc aatggctatt ccgttcctat
     7501 ctaaaggagt taattcttgg ttattatcta ctacagtagt tggttcattt gtactatcag
     7561 caaatgtagg aattgtagtt ccagttacac taattccaat agttaaaata cctaaagata
     7621 aaataa
//
LOCUS       DAXQKX010000094         7596 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.097, whole genome shotgun sequence.
ACCESSION   DAXQKX010000094 DAXQKX010000000
VERSION     DAXQKX010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7596
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.097"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(134..424)
                     /locus_tag="ACF3MF_002602"
     CDS             complement(134..424)
                     /locus_tag="ACF3MF_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928505.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFSHSLGLMISLTIFAIVLFFLNKK"
     gene            complement(542..802)
                     /locus_tag="ACF3MF_002603"
     CDS             complement(542..802)
                     /locus_tag="ACF3MF_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928506.1"
                     /translation="MGVDHLIVLSKLLFWIPFIIMTSAFFYLFKRPNKYLLLSACPMI
                     YFIHKIRGFYYYDSGISLFCYEIGLLASAIFFIFVLEYFRKK"
     gene            complement(939..1352)
                     /locus_tag="ACF3MF_002604"
     CDS             complement(939..1352)
                     /locus_tag="ACF3MF_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HFE3928507.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1808..2293)
                     /locus_tag="ACF3MF_002605"
     CDS             complement(1808..2293)
                     /locus_tag="ACF3MF_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928508.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2432..2647)
                     /locus_tag="ACF3MF_002606"
     CDS             complement(2432..2647)
                     /locus_tag="ACF3MF_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HFE3928509.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2871..3671
                     /locus_tag="ACF3MF_002607"
     CDS             2871..3671
                     /locus_tag="ACF3MF_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFE3928510.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3690..5558
                     /locus_tag="ACF3MF_002608"
     CDS             3690..5558
                     /locus_tag="ACF3MF_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFE3928511.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5551..6042
                     /locus_tag="ACF3MF_002609"
     CDS             5551..6042
                     /locus_tag="ACF3MF_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HFE3928512.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6030..6584
                     /locus_tag="ACF3MF_002610"
     CDS             6030..6584
                     /locus_tag="ACF3MF_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HFE3928513.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6602..>7596
                     /locus_tag="ACF3MF_002611"
     CDS             6602..>7596
                     /locus_tag="ACF3MF_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HFE3928514.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVPTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2707 a         1214 c         1442 g         2233 t
ORIGIN      
        1 ttactatgaa taacataata agaaagtaaa gtggattgat ttgagatctt tttatacttc
       61 aaaaaagata acacccaact ttcaaaaata tgttttggaa gttgggacaa acgagttaat
      121 acattttaat acattatttt ttattcaaaa aaaatagcac aatggcaaag atcgtaagag
      181 agatcataag ccccaatgaa tgactaaaaa gaaaagcaga atcacatgcc atatcatccc
      241 atatttcttc aagaaaataa ataagcggga aaaagggaag gaatagtaga acatcgatcc
      301 agcaccattt ttttcttctt ttgaaataac ataaaacaat aaacatgaac gtgcagggaa
      361 gtaaaaacaa agctttactc ataactaaca aaataccagc tccttttatt tttttctccc
      421 ccacattcaa agagtaacaa tggtatgtac ttaataatag aaaaatggat caacttgtat
      481 gaataacagc tgaaaagatc tgcaccaaat aaaaaacttc cagccaaaac tgactggaag
      541 tttatttttt tctgaaatat tctaacacaa atatgaaaaa gatggccgaa gctaataagc
      601 cgatttcgta gcaaaacaat gagataccag agtcgtaata ataaaatcct ctaatcttat
      661 ggataaaata gatcatcgga caagcagata agagtaagta tttgttaggc cttttgaata
      721 agtaaaagaa agcactggtc attatgataa atggtatcca aaacaaaagt ttacttaaga
      781 caatcaaatg atcaactccc atatttttta ccaagagaga tcataacatc tttatcgtaa
      841 aaacaaaata tttttttgct cattttgaaa atttaaacat actcgttctt atccaaatat
      901 ataaaaatcg cccctcattc atcgagaggc gataagttct aatttaactc aatttttttt
      961 gtttcttttg gctgataagc tgttttaggt aataccaatt tcagcacacc gtttttaaag
     1021 gttccagtga ttttttcttc atcaacatta ggaagataga atgaacgttt gtaagagacc
     1081 gaatgtcttt ctttccgtac atagttgcca tcttctttat cttctgtatg ggactcatga
     1141 ttggcggaga tcgtcaaagt attatctgaa tattcaactg tcgtgtcttc tttgtcacag
     1201 ccaggcatat cagcagttag tttgtattct ttttcatttt cgactaaatc tacttttgga
     1261 taacttgaaa cacctaaaaa atcattgaat gctggactaa acacgtcatt gaaatcaggg
     1321 aacatgtcgc gaatgctagg tacatttgcc atttttgatc atcctttcaa taagtatttt
     1381 ttatttatcc ctatttacgt aataactcta ttttgaaaaa aatgcaagta taatggttag
     1441 ctttgtgaat atttcatcta atacgataca aaggctatct ttctaatttg aaaaagggat
     1501 cattaaaata ataagaagaa aatatgtcaa aaggtaaaaa agtaaattct tctatccaaa
     1561 tatagaaaaa ttgaatctag aaaaccgccc gacaataaat ttcattaact cagttgaccg
     1621 aaaatgaagt agataccaaa aatttatcaa gagagcaagt agagaagtga gtatattcat
     1681 aagagaaata gctgtaacga attattaggt taatgcaaat gcttatttat actccgtata
     1741 actttctcag aaaaaatgat accaataatg acttgctagt actgtaaatc cgtataatat
     1801 catctaatca aaatggtgtt ccatttgcat ctgtcatcgt aatcgatcct tcgggtgaca
     1861 ctcgataaaa accaacgctt ccagatcctc cttgggaacg gatttgtttg ctggaagctg
     1921 tgaacaaata atctcgatca attttttgat aaaagctaat aacaatatcg tcactttgta
     1981 attcggaacg gtgggcaata agaaatagaa gtgctttgtc agagttttct aatggaagag
     2041 aaggtacagt gctttcttgc atttcagatg ttgaagaaat gctaaacgac tgaatacttg
     2101 attggctatg ttgcgaatct acattaccag tagaagtatt agtaatggaa gtagtagaag
     2161 tacttttagt tgaaccaacc tcagttgttg aaatggctgc tgaagattct ttaacagaat
     2221 tctttgtttt atatccacag gcagaaaaaa gtattacagt tcccaacaag cctgcgtaaa
     2281 tccctttatg catgatagct cctcctaaaa tagattatct ttattcagta tatcacttaa
     2341 acaaagaaaa gcagatggtt taaaatgaaa aaaccttccc aataaaggga aggttcatga
     2401 agataataac ttttttaata attatagctt tctaatatct ttcatcaact tttctagtaa
     2461 tcattgggaa aaatttcaag cagtagatcg cacaaatacc tacgacgata taaatgatct
     2521 tcgcaaaaat agttgttgaa ccaccagcaa tcatagctac taaatcaagt tcgaacaagc
     2581 ctaccaacag ccagttcaac cctcccacaa tcaataaagt taatgcaata gcatctaaag
     2641 ttttcattag aattctcctt tcttaaatga taaaacaatt atatatcaaa aagagaaaca
     2701 ttgcttatat aacgctcagg aattttagca atctatgcaa aaagatgaaa attttttttg
     2761 ctcttccatt agtacacatt ttttagctga agctgtaaat ttcatgtctt aatttttttt
     2821 agtgagcttt tatactggat ttgtaagaaa aaagaaggag aggatcacat atgtcggatt
     2881 ggttggatat tgcaggaaaa gtagtaattg taactggagg ttcctcagga attggaagaa
     2941 gtatcgtcga aaatttgttg aagcagaatg cacaagtagc gaattttgat gtaactgaat
     3001 gccgtataca gcatgaaaac ctactatctt taaaagtcga tgtgtcttct aaaacggaca
     3061 tagaagaagg gatatataaa gtaatgaaac atttcaagac gatcgatggt ctagtcaata
     3121 atgcaggaat aaatattcct tctcttctaa tagatagaaa tcatccaaaa agcaagtatg
     3181 aattatcaga acaagttttt gataagatga tcgctgtcaa tcaaaaaagt gtatatttga
     3241 tgagccaagc agttggaaga atcttggtgc aaaagggatc aggagtgatc gtgaatcttt
     3301 cttctgaatc aggattggaa ggatcagaag gacagagctg ttatgctgct acaaaagcag
     3361 cgatgaacag ttttactcgt tcttgggcaa aagagttagg aaagaggaat gttcgtgtgg
     3421 taggtgttgc accagggata ctggaagaaa ccggtttgag aacacaagaa tatgaagaag
     3481 ctctttctta tacgagaggt ataagcgtcg aacagctgag aaacggttac agtcgaacaa
     3541 gtacgatccc tctaggaagg agtggtaagc tgcaagaagt ggcggatcta gtctgctatt
     3601 atctttcaga aagatcaagt tatatcactg gagtcacgac taatatttca ggaggtaaaa
     3661 caagaggata aaggataggg gggacgcacg tgacgctagt aaacagatgg taccaattat
     3721 tgaaattact agtcactcac aagaaagttt caatccagga agtgcaaaaa gaaatcaaaa
     3781 ccagtaatca aaccataaaa aaagatattg gggagttgaa tgaagaaatt gccggtattg
     3841 caaaaatcat ccaaaaaaac aaacattttg aacttgaaat ttatgatttt gatttttttg
     3901 atgagatcat gcaaggaaaa ttgaaaacag ccagtgattt caattcggca tccaaaagaa
     3961 tcgcttattt actaaatagg ctgatcgaaa cagaggattt cttacgtatg gatgatttgt
     4021 ctgaagaagt cggtgtcagc agaggaacag tggtcaagga tctaaagaca ttaaaagaga
     4081 tgatcaatga ttttgatgta aagattacag gcacaccaaa taaaggacta agaataatag
     4141 gagatgagct agaattacga ctacttttat tttattttgt ttctccctac ttttcagaga
     4201 cgaaaacaga acagtttcta gaagaaaaac aagcaatcaa acattttcag aagaagacga
     4261 atgctagtaa acaagaaatc acccttttaa cgaaagttat cggtatttct ttgaatagaa
     4321 tctctagtaa ctatctgttg aagaagccca tcaatcgtta cagtgggtgt tttgaatata
     4381 tccaagaatt caatgaactg atcaatcagt tggaagaaat ctatgaacta actttgagcc
     4441 aatatgaaaa agattttatc agttttcctt tgaacatcat caacacaagt ataacgatga
     4501 taaggaaagc taactctgat ttgcgcttat atttcgaccc catgatgatg cgtattcgac
     4561 gattagatct cattgatctg gatgagtcct tcttatatca agagatgaaa cagcacctct
     4621 ctttattgat aaatcgggta atttttcgtt atcgattgac tgatttattt tatggtgaga
     4681 tagaaaaaaa gtatcctttt tcttaccaaa tcgctagcga atgcatacaa gcattagaag
     4741 ctatcttgca acataagatc tctaaagtag agatcagcta cctaacgttg tatttggagt
     4801 tagcatttcg atatcaaaaa gagcattttt cctctaaaaa agtagccatt gttcatacga
     4861 caggaaaagg aacagcatta atgatccaaa gacaaatcaa aaggatattg gggagggata
     4921 tacaaataac acatgtttca gaagaacaat atgaaaaagt agatctaaac aaatatttcg
     4981 ctgtttttac aacgattccg ttaaaaaatg taaatgaaga gacaccggtg atccatttga
     5041 ctaatctttt tgatgactct tggttaaggg cacaatggca aaaagcaaaa aaaaagcgat
     5101 tagccgggtt tcattctact gtttttttct atcaaatatg gaaagaaaaa aagacgtatc
     5161 aagaatattt aaacaaatta gtcgctcctt tgatcagagg ctattatgtg gatgaagaat
     5221 ttgaaaaaag gatcttgaaa agagaatatc agcaaagcac atttgttaac aaagaatttg
     5281 cttttcctca cacaaccaac cagctatctc aacacattgt tttatcagta gggctaataa
     5341 ctgatcaagg tttagcagaa acaggaggaa atggagttat ttttttattt gccatacctg
     5401 aagaaatgac ggctgaagtt gagaatgaat tatttgagct atacgatatc ctatttgaac
     5461 tcataaaaat gggaatagat gagtttattg aattagcacc gacacaagaa tcatttttaa
     5521 aactaatcaa aagtaaagga gagagacttc atgaatgata tgtatctatt catagttttc
     5581 gcagcttcag cttatgtgct gcaagcagtt atcagttgga agcaactaaa gcatttcaat
     5641 caaacatata gcgaactgcg aagaaaagga aaagtagcga ttggtaaacg acctgggaaa
     5701 atccgttcag gcacgattgt tatgctagct atagacgatc atgatcaagt tttagaagtc
     5761 agaaaaatgc aaggggttac atctttggca aaatttcatt cattacctgt ctatgcgggt
     5821 gaagatatcc attacatcga tcgttaccat ccctcagttc gagcggaaga tcgtttgaca
     5881 caagcagctt tagaaaatgc cagagaagta tacttacgaa tagaggcagg aaatgaaaaa
     5941 agtgaacaac cttcattgcc ttttattgct atgctcaata attttcggat atggaaaagt
     6001 acgatcaaag aaaaaaggag tgacaaacga tggatatcat aacaaaattt gctgagggat
     6061 ttatgaggct gttccaaaca ggtgcagaaa cattcataag ctggatgaca ggaatcgtac
     6121 cagttgtctt gatgctgatg gttgcaatga atacgctgat tgctttttta ggtgaagacc
     6181 gagtaacgaa agtagccaaa ttatcagcga aaaatccgct tactcgttac cttgtgttac
     6241 cgttcttatc tgcttttatg ttgggaaatc ctatgtcatt tacaatggct cgtttccttc
     6301 cagaatacta caaaccaagc tattatgctg ctcaagctca attttgtcat acgagcaatg
     6361 gtgtattccc ccatattaat cctggagaat tgtttgtatg gatggggatt gctcaaggga
     6421 tcgaaacctt agggctaaat tcgatggagc tggctatccg atacttgctt gtgggactgc
     6481 tgatgaactt tattggtggt tggataactg attttactac tggatttgta tgcagacagc
     6541 aaggaatcgt tcttagcaaa aaagtagagc tttcagttga ttagagaaag gagagtttta
     6601 aatgtatggt gatattaaga tcgtaagagg aaacggcggg tatggaggtc ctttgattat
     6661 taggccgaca aaagataaac acaagttcat ctatgtcaca ggtggaggtg agaggccaat
     6721 gatcgtagat aaaatagaag aactgacagg tatggagtct atcaatgggt tcaaaacatc
     6781 aatacctgat agtgaaatcg cgcttgcaat cgttgactgt ggagggactc ttagatgtgg
     6841 aatttatcct aaaaaaggga taccaaccat caatatcgtt cccacaggaa aaagtggccc
     6901 attagcacaa tatatcactg aagatattta tgtttcagca gtagggttag aacaaataca
     6961 gccactaatg gaaactgatg ataacaaaga aacagtaaat actgcatctc cagataaaaa
     7021 gtacaaatat gatacttcta aaaagataac cgagcaaaaa gcagagcagc aaaactggat
     7081 agcaaaaatt ggaatgggcg cgggaaaagt agttgctaca ttcaatcaat cagcaagaga
     7141 agcagtagat acgatgatcc ggacagtgat cccttttatg gctttcgttt cccttttgat
     7201 tggtgtgata caaggttctg ggatcggtaa tgtatttgct aacattatgg cacctttagc
     7261 aggaaatgca gttggattaa caatcattgg ctttatttgt tcactgccat ttttatctcc
     7321 tttgcttggt ccaggggcag ttattagcca agtgattgga acattgatcg gtgtagagat
     7381 tgggaaagga aatattcctc cccaattagc attaccggca ctatttgcta tcaatactca
     7441 aaatgcatgt gattttattc cagtcggtct aggtttggaa gaagcaaaag ctgagacagt
     7501 agaagtaggt gtaccatcag ttctttattc aagatttctt aacggcatcc cacgagttat
     7561 cattgcttgg gtagcaagtt ttggattata tagctg
//
LOCUS       DAXQKX010000095         7540 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.098, whole genome shotgun sequence.
ACCESSION   DAXQKX010000095 DAXQKX010000000
VERSION     DAXQKX010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7540)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7540)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7540
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.098"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            184..966
                     /locus_tag="ACF3MF_002612"
     CDS             184..966
                     /locus_tag="ACF3MF_002612"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HFE3928515.1"
                     /translation="MVKKIDFHIHTVSSHKDYDFSYSPEWLKKYVRAAELDAIAITNH
                     DLFDESNFKQIQYDLPNTKVFPGIELSLEEGHVNIIFPEEDSPNLVHFSEWLSTQNLG
                     QNGKVSTEDFCTHMSNWENGIYIFELGKSNALSVPEKLESICSVGGVANQLKFQTFYR
                     IEDALTPVLFSDAHADDNDPEEKRKNIEILKNKNTYLQIDNCSFQEIKNCLMDKTKVG
                     INLRYLRDVIDIENHTVSTGLNLIVGKRGTENQFFRNDKKIL"
     gene            908..2224
                     /locus_tag="ACF3MF_002613"
     CDS             908..2224
                     /locus_tag="ACF3MF_002613"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFE3928516.1"
                     /translation="MLVNEVLKTNFLETIKKYYDYEDIYEIAQFETSNANDFIKKQRT
                     EQGKNALDIWKKRYDSQFSAIQDYLKNNEEDFNQDVEKFVESVKQFAKDSTTSNSTSK
                     YQLIKESNLEEISTKNLETHLYKLLDLINSPDLWELLSNSVEKRRVFVETYSEVRNLF
                     VQKQQNNKVREKVNDILGSVKKIVQSKTGITPVVDCEFSKIIQKHQIEKEINNFMQKI
                     VCNTEIKKEKIYGYQIIVKLSPFINATQFRKDRTSEAVQDDLIVPYKSGQYITFLRNL
                     KKRSFFNPSILEEYLLHLEVNLLDSDGVPASGGQAVGFALMMRLEEAKTKPIILIDEP
                     EASLDNEYIRKELRDAIRNLSASSTVFVVTHNSTLGALLEPDYLIVTTKDKEKGYRVL
                     TGEFSSHLISTKSDTTESSYEKFVEAMEAGIETYKKKGEIYESLNS"
     gene            2205..2489
                     /locus_tag="ACF3MF_002614"
     CDS             2205..2489
                     /locus_tag="ACF3MF_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928517.1"
                     /translation="MKVLIVNSGKSKFVIGENNVEPENLSRDDLLMILNNIYESEENV
                     VIPSIEELDEIRNPIEKEIVQQIIQKISDFSNNVENIRQEVQAQFPVIED"
     gene            2527..2850
                     /locus_tag="ACF3MF_002615"
     CDS             2527..2850
                     /locus_tag="ACF3MF_002615"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928518.1"
                     /translation="MVGIDNDSNFKSYEFEKTYDFSVEIPIVDEDTGEYTREIELVAG
                     QITFFGDADWDSTEKEYVYNFSWEESTRTFSHYGNAPDKEDEFIKDFKEYLLQQGVER
                     YNIGW"
     gene            2901..3125
                     /locus_tag="ACF3MF_002616"
     CDS             2901..3125
                     /locus_tag="ACF3MF_002616"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+.
                     GO_component: GO:0030127 - COPII vesicle coat [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0006888 - endoplasmic reticulum to Golgi
                     vesicle-mediated transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Sec23/Sec24 zinc finger-containing protein"
                     /protein_id="HFE3928519.1"
                     /translation="MTERFPDTDWWCDRCGAHLNSQNNFDDYKYTWKCTECGFKNSIS
                     KDNIYESHEEYYNTGDDDSGLLRSIFKKLF"
     gene            complement(3512..4132)
                     /locus_tag="ACF3MF_002617"
     CDS             complement(3512..4132)
                     /locus_tag="ACF3MF_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HFE3928520.1"
                     /translation="MATKVFISFRFSDGKEIKDELVDLFDESTEVINRSEDVDRSQMS
                     KDTIQEYLYEKLKDTSVTIVLLTPEAVSYRKNWIGNYDDWIYDELRYSLEDRNNNRAN
                     GVVAVYTDDAKDMILESSSHYCAHCQETKSCRTLKSFDNLARKNMLNIKQSYKKNPCN
                     DLYDDSHDSYISLVSLEEFKQDYTKYIDNAKDKRDRLHEFNIYKRM"
     gene            complement(4132..5544)
                     /locus_tag="ACF3MF_002618"
     CDS             complement(4132..5544)
                     /locus_tag="ACF3MF_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HFE3928521.1"
                     /translation="MRQELFIKKFSKAIQEGNAAVFAGAGTSVDAGFVNWKNLVAPFA
                     NEIDLDIEKETDLVGLTQYYINKKRNRGSVNQEIIDQFSSQYAETEVMNLLTRLPIST
                     YWTTNYDKVIENGLKNNNRRGDIKRKTDDLAISIRDSDAIVYKMHGDVDSPNDAVISK
                     DDYERYSEKNSLFVTALRGDLVSKTFLFVGFGFEDPNLESILGKIKNLLGERTRDHYC
                     IQKKVLEQDYKNREEYSYAKIKQELKIEDLKRYGIDTVLVDDYSEIPKLILKIEEEYF
                     KNTIFISGSISDYNENWSQEKVNQFCYNLSRSLVSKNYKIISGFGLGVGSSVINGALD
                     EIYNTKYRHVSEHLGLFPFPQHDAGEKSLAKRWTENREQMISEAGICIFIFGNKLVNG
                     EVVLASGMMEEFRIAKERGKVIIPIGSTGFVAKEIFDEMKESGDYSYINDYWNDLENE
                     EDVIKVFNTINEIIEGVRFR"
     gene            complement(5574..6734)
                     /locus_tag="ACF3MF_002619"
     CDS             complement(5574..6734)
                     /locus_tag="ACF3MF_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003953 - NAD+ nucleosidase activity
                     [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HFE3928522.1"
                     /translation="MGIVMRQYNNFYIKFQRQFKKAHGQVIETMPLEFSNKEYIERFK
                     YMFPDKILLIERERNYWYGKRIIRKNLSKIRCKGMSLETDSFILSTSKHIRKIKRESL
                     ASNEEMVKKVNTARTISLEKLKAESLRSKRKLNYIQEVEPPYLRNYRNRFFKTHDLHE
                     RLEIIRELSKYDSKEVREFFYAINGHIRNQSLKIEVQSYFQSLSLPFRLSRKKKGKKN
                     FIDNEIVKNKKGPDELKKRLYINDLEKIKRFDIFVSHNSRDEEKIIEFYKKFNKKGQV
                     VYIDWINDKYDLRREWCNASTVDIIKERIKQSDVFVLYFSGETLNSQWCTWELGYADA
                     LGKKICVYFSEDINRKGIPKFYVAYPELQMSKNIYVKIRGNEDILLKEWKKL"
     gene            complement(7140..>7540)
                     /locus_tag="ACF3MF_002620"
     CDS             complement(7140..>7540)
                     /locus_tag="ACF3MF_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFE3928523.1"
                     /translation="PTEPSKPTEPSEPTEPSTPTEPSTPTEPSTPTVPNKPVDTNPIE
                     NPVNTDTGVVIVAVEDSKPIIQLANGTTKKVEAKEIGANVQKDGTVTVKGSDGKMKVL
                     PKTGDTENIALSVLGSLMVLGSAFIFKKRI"
BASE COUNT         2535 a         1213 c         1108 g         2684 t
ORIGIN      
        1 caacagaacc atttcgaaga tccttaattt aaataaatta gaggaggatt tatattgccg
       61 caaacaagtt ctaaaatcaa tgtcactgag tggttgtttg tatggcggat atcaagcata
      121 ttagtcagcg tttacatgat ataatcaaga catgagtttc caaattatta tggaggtcta
      181 catatggtta aaaaaattga ttttcatatc cacacggttt ctagtcataa agattatgat
      241 ttttcttatt ctccagagtg gctaaagaaa tatgttcgag cagctgaatt agacgcaatt
      301 gctattacta atcacgattt atttgatgaa agtaatttta aacagatcca gtatgatttg
      361 ccaaatacta aggtttttcc aggtatagaa ctgagtcttg aagagggaca tgtaaatatt
      421 atttttccag aagaagatag tcctaatcta gttcattttt ctgaatggct atctacccaa
      481 aatttaggac agaacggaaa agtatctact gaagattttt gtactcacat gagtaattgg
      541 gaaaatggaa tttatatctt tgaactagga aaaagtaacg ccttatcagt accagaaaaa
      601 ttggaatcta tttgttctgt tggtggagta gcaaatcaat tgaaatttca aactttttat
      661 agaatagaag atgctttaac accagtatta tttagtgatg cgcacgctga tgataatgat
      721 cctgaagaaa aaaggaagaa tatagaaata ttaaaaaata aaaatacgta cttacaaatt
      781 gacaattgct cgtttcaaga aataaagaat tgtttaatgg ataaaacaaa agttggtata
      841 aaccttagat atttgaggga cgtaatcgat attgaaaatc acactgtttc aactggatta
      901 aatttaattg ttggtaaacg aggtactgaa aaccaatttt ttagaaacga taaaaaaata
      961 ttatgattat gaagatattt atgagatagc tcaatttgaa acatcaaatg ccaatgattt
     1021 tataaaaaaa caaagaacag aacaagggaa aaatgcgtta gatatatgga aaaaacggta
     1081 tgactcgcag ttttctgcta ttcaagacta tctaaaaaat aatgaagaag attttaacca
     1141 agacgtagaa aaatttgttg aaagtgtgaa gcaattcgcc aaagattcga ctacaagtaa
     1201 ctcaacttcc aaatatcaac ttattaaaga atcgaatctt gaagaaattt ccacaaaaaa
     1261 cttagaaaca cacttgtaca aattacttga tttaattaat agtccagatt tatgggagct
     1321 gttaagtaat tcagttgaaa aaaggagagt ttttgttgag acatatagtg aagtaaggaa
     1381 tttgtttgtt cagaaacaac agaataacaa agttcgagaa aaagtaaatg acatactagg
     1441 ttctgtaaaa aaaatagttc aatctaaaac tgggattacc cctgttgttg attgtgagtt
     1501 ttcaaagata attcaaaaac atcagattga aaaagaaatt aataatttca tgcaaaaaat
     1561 agtctgtaat actgaaataa aaaaagaaaa aatttatgga taccaaatta ttgtgaagct
     1621 atctccgttt ataaatgcta ctcagtttag aaaagatcgt acaagtgaag cagttcaaga
     1681 tgatttaatt gttccctata aaagtgggca gtatattaca tttttaagga atttgaaaaa
     1741 aagaagtttc tttaatcctt ctattttaga agaatatcta ttgcatttag aagttaacct
     1801 gctggattca gatggtgtac cagcatctgg gggacaggct gtgggatttg ctctaatgat
     1861 gagattagaa gaagcaaaaa caaaaccaat aattttaatc gatgaacccg aagcgtcact
     1921 tgataatgaa tacattcgga aggaattaag agatgctata aggaatttgt ctgcaagcag
     1981 cactgttttt gtggttacac ataattcaac attaggagca ttactggaac cagattatct
     2041 aatagtgact acgaaagata aagaaaaggg atatcgcgta cttaccggtg aattttcttc
     2101 tcatcttatc tctacaaaat cagatacaac tgaaagtagc tatgaaaaat ttgtagaagc
     2161 aatggaagca ggaatagaaa catataaaaa gaaaggagaa atatatgaaa gtcttaatag
     2221 ttaattcagg aaaatcaaag tttgttatag gtgagaataa tgtggagcca gaaaaccttt
     2281 ctagagatga tttattaatg atactaaata atatttatga atctgaagaa aacgtggtga
     2341 ttcctagtat tgaagagtta gatgagatta gaaatcccat tgaaaaagag attgttcaac
     2401 aaattattca aaaaatttca gatttttcaa ataacgttga aaatattcgc caagaagtgc
     2461 aagcgcagtt tcctgttata gaagattaaa atttatatgc taataaaaaa taaaggagtg
     2521 aggaaaatgg taggaataga taatgatagt aatttcaagt catatgaatt cgaaaaaaca
     2581 tacgatttta gcgtagagat tccaattgta gatgaagata cgggggaata tactagagaa
     2641 atagaattgg tagctggaca aataacattt tttggagatg cagactggga ttcaacagag
     2701 aaagaatatg tttataattt ttcttgggaa gagtctacta gaacatttag tcattatggt
     2761 aatgcacctg ataaggaaga tgagtttatt aaagatttca aagagtattt attacaacaa
     2821 ggagttgaga ggtataatat tggatggtaa atgttgaaat taattataaa aatttttaaa
     2881 tatgtaggga gagatatact atgacagaaa gattcccaga taccgattgg tggtgtgacc
     2941 gttgcggggc acatctgaat tctcaaaata attttgatga ctataaatat acatggaaat
     3001 gtactgagtg cggttttaaa aatagtattt caaaagataa tatatatgag agccatgagg
     3061 aatattacaa tacaggtgat gatgattctg gtttactaag atcaattttt aagaaattgt
     3121 tttagtgctg aattacttac agattttctg agaatgcctt gaaacgttaa tcttccggta
     3181 gttaaaggag aggtaatcac ttttcttttt tttacttcat tgttccataa ctttatccaa
     3241 ggtgattaat ttgacataga acttgtgatg gatttatgga cacgtgtttc aattctttta
     3301 gagaaaaatc ataccaaaat agcagtgtcc agaaatgaac tattttatgg acatgagata
     3361 aaaaagaaaa acagccattt ccgtttttct tttttatctt tgtgtctaaa tatttgacat
     3421 tagtccaaac aaaagcactt tataaatctt gtacagaaaa gtgttgcctt ttcatttatt
     3481 ctaaagacaa tttatgctaa atcaatgctc ttcacattct tttatatata ttaaattcat
     3541 gtagcctatc tcttttatct tttgcattat caatatattt agtataatcc tgtttaaact
     3601 cctccaaact tactaaagaa atataagagt catgactatc atcataaaga tcattacatg
     3661 gatttttctt atagctttgc tttatattca acatattctt tcgtgctaaa ttgtcaaaag
     3721 atttcaaagt tctacatgat ttagtttctt gacaatgtgc acaatagtgt gaactacttt
     3781 ctagtatcat atctttagca tcatctgtat atactgctac tacgccattt gctctgttgt
     3841 tatttctatc ttccaaggag tatctaagtt catcataaat ccaatcatcg taatttccaa
     3901 tccaattctt tctataagaa acggcctctg gagttaataa tacaattgta accgatgtat
     3961 cttttaactt ctcatataga tattcctgaa tagtgtcctt actcatttga cttctatcaa
     4021 catcttctga tctattaatt acctcagtag attcatcaaa taaatcaact agttcatctt
     4081 taatctcttt tccatcacta aaacgaaatg aaataaatac ttttgttgcc attatctaaa
     4141 tctaactcct tcaataattt catttattgt attaaaaact tttataacat cttcttcgtt
     4201 ctctaaatca ttccaataat cgtttatata tgaatagtcc cctgactctt tcatttcatc
     4261 aaaaatttct tttgcaacaa accccgtaga accaattgga attattactt ttcctctttc
     4321 tttagcaatc cgaaattcct ccatcattcc agatgcaagt actacctcac cattaactaa
     4381 tttattacca aatataaaaa tacagatccc agcctcactg atcatttgtt cacgattttc
     4441 agtccaacgt ttagctagag acttttcccc agcatcatgt tgaggaaaag gaaataatcc
     4501 aagatgctca ctgacatgcc tatacttagt gttataaatt tcatcaagag ctccattaat
     4561 aacactacta cctactccaa gtccaaaccc tgatataatt ttataatttt ttgaaacaag
     4621 tgaacgcgat aaattataac agaattgatt taccttttct tgactccaat tttcattgta
     4681 atcggagata ctacctgaaa taaaaattgt atttttaaaa tactcttcct ctatttttaa
     4741 tatcaactta ggtatttcag aataatcatc aactagaact gtatctatac cgtacctttt
     4801 caaatcttct atttttaatt cttgtttgat tttagcatag ctatattcct ctcgattttt
     4861 ataatcttgc tctaatacct tcttttgaat acaataatga tctctagtac gctccccaag
     4921 taaatttttt atctttccca agatggattc taaattagga tcttcaaaac caaaccccac
     4981 aaacaaaaat gttttggaaa ctaagtcacc tcgtaaagct gttacaaata gggagttttt
     5041 ctcgctatat ctttcataat catcttttga aataactgca tcattaggtg aatctacatc
     5101 accgtgcatc ttataaacaa tcgcatcgct atcacgaata ctgattgcta aatcatctgt
     5161 cttccttttt atatctcctc tgcgattatt attttttaag ccattttcaa ttaccttatc
     5221 ataattagtt gtccaatatg tagaaattgg aagtcgtgtt aacagattca taacttctgt
     5281 ttctgcatat tgactagaaa attggtcaat tatttcttga ttcaccgaac ctctatttct
     5341 ttttttattg atataatatt gagtcagtcc tacaagatcc gtttcttttt caatatctaa
     5401 atcaatttca ttcgcaaacg gtgctacaag gtttttccag ttaacaaatc ctgcatcgac
     5461 cgatgttcct gcaccagcaa acactgctgc atttccttct tgtatagctt tcgaaaattt
     5521 ttttataaat aattcttgtc tcatattacc ctcatttcta atttattata agcctataat
     5581 tttttccact ctttaagtaa aatatcttcg ttccctctaa ttttgacata tatatttttt
     5641 gacatttgca attcaggata agctacatag aattttggaa taccttttct atttatatct
     5701 tctgagaagt aaacacatat cttcttccct aatgcgtcag catatcccaa ttcccaagta
     5761 caccattggg aattcaaagt ttctcctgaa aagtataata caaaaacatc tgattgtttt
     5821 atacgctcct tgataatatc aactgtggag gcattgcacc attcacgcct taaatcgtat
     5881 ttatcattta tccaatctat ataaactacc tgtccttttt tattgaactt tttatagaac
     5941 tctataattt tttcttcgtc tctagaatta tgcgatacga atatatcaaa tctttttatc
     6001 ttttctaaat cattaatata taatctcttt ttcaattcat ctggtccttt tttatttttt
     6061 acaatttcgt tatcaataaa attcttctta cctttctttt ttctgctcaa cctaaaaggt
     6121 aaagataaac tctgaaaata tgattgaact tctattttta atgattgatt tctaatatgc
     6181 ccatttattg catagaaaaa ctcccgaact tcttttgaat catacttaga aagttctctt
     6241 ataatttcca atcgttcatg taaatcatga gttttaaaga atctatttcg ataattcctt
     6301 aaatatggag gttcaacttc ctgaatataa tttaattttc tcttgcttct caaggactct
     6361 gcttttaatt tttctaaaga tattgttcgg gcagtattta ctttttttac catctcttcg
     6421 ttactagcta gactctctct ttttatcttc ctaatatgtt ttgaagttga aagtataaaa
     6481 ctatcagttt ctaaagacat acctttacat cgaattttgg aaagattctt tctaataata
     6541 cgttttccat accaataatt tctttccctc tctatcagca atattttatc tggaaacata
     6601 tatttaaagc gttctatata ttctttatta gaaaattcta atggcattgt ttctataact
     6661 tgtccatgag ctttcttaaa ctgtctttga aattttatat aaaaattatt atactgcctc
     6721 attacaatcc ccatactcaa taagtccccc ccactactta atattatttt gcagtatatt
     6781 gtcctctctg tcttttttct caatgttaca ctaaaataga ttttttggaa aactttgcaa
     6841 cagaacctat ctcgttagtt atcgcaccac ttttagtggt tctaataatc acattagttg
     6901 atcattggtt agatgattag acgatggcaa gcaagttgct ttctaactca cacgcttgta
     6961 ttcgcaacaa gtgaaaagaa aagccgacct actagcaata tgttattggt gttgcctaga
     7021 acgattctaa gcgcttgttt aattttaagg tatacattcc ccttcaaaac gtcctagaat
     7081 gattcaataa aagcatggct gctagtgaaa cttgcgacca cgcttttata aatacttaat
     7141 tagattcgct ttttaaaaat gaatgctgat cctaatacca ttaatgaccc taggacagac
     7201 aatgcaatat tttctgtgtc tcctgttttt ggtaaaactt tcatttttcc gtctgaacct
     7261 ttaaccgtta ctgttccgtc tttttgaacg tttgcaccaa tttctttagc ttcaactttc
     7321 tttgttgttc cgtttgctaa ttgaataatc ggtttactat cttcaactgc aacaatcaca
     7381 acgcctgtat ctgtattaac tgggttttcg attgggtttg tgtctactgg tttgtttggt
     7441 actgttggtg tacttggttc cgttggtgta cttggttccg ttggtgtact tggttctgtt
     7501 ggttcgcttg gttctgttgg tttgcttggt tctgttggtt
//
LOCUS       DAXQKX010000096         7493 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.099, whole genome shotgun sequence.
ACCESSION   DAXQKX010000096 DAXQKX010000000
VERSION     DAXQKX010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7493
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.099"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(69..298)
                     /locus_tag="ACF3MF_002621"
                     /pseudo
     CDS             complement(69..298)
                     /locus_tag="ACF3MF_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320737.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(282..479)
                     /locus_tag="ACF3MF_002622"
     CDS             complement(282..479)
                     /locus_tag="ACF3MF_002622"
                     /inference="COORDINATES: protein motif:HMM:NF016526.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HFE3928524.1"
                     /translation="MLLRFLFSFCCALYTLRIFTGGVHLNSNILCYFMSVVIVIVAYQ
                     CMFIFRNVDFIILGLMFEFFW"
     gene            complement(625..1503)
                     /locus_tag="ACF3MF_002623"
     CDS             complement(625..1503)
                     /locus_tag="ACF3MF_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFE3928525.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(1542..2660)
                     /locus_tag="ACF3MF_002624"
     CDS             complement(1542..2660)
                     /locus_tag="ACF3MF_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 172 protein"
                     /protein_id="HFE3928526.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(2657..4756)
                     /locus_tag="ACF3MF_002625"
     CDS             complement(2657..4756)
                     /locus_tag="ACF3MF_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HFE3928527.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(4807..5628)
                     /locus_tag="ACF3MF_002626"
     CDS             complement(4807..5628)
                     /locus_tag="ACF3MF_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFE3928528.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(5625..6434)
                     /locus_tag="ACF3MF_002627"
     CDS             complement(5625..6434)
                     /locus_tag="ACF3MF_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFE3928529.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(6455..6949)
                     /locus_tag="ACF3MF_002628"
     CDS             complement(6455..6949)
                     /locus_tag="ACF3MF_002628"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFE3928530.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(6961..7461)
                     /locus_tag="ACF3MF_002629"
     CDS             complement(6961..7461)
                     /locus_tag="ACF3MF_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFE3928531.1"
                     /translation="MIKPMFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLS
                     SIQLLTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITK
                     TFLEKEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVN
                     EEEDFF"
BASE COUNT         2302 a         1704 c         1241 g         2246 t
ORIGIN      
        1 taaaataaaa aatttattgc aaaaaaaata gaagtgacaa aattatcaat catttcaagg
       61 taatataact acctgagttt attatcgatt aaaatgctaa ctacatttgc aagagaagcg
      121 agagttaaag gtaaatatag aatttctact tttttagcaa tagaaatagg aataaaatat
      181 ttaaaatgta tagaaacttt cttttttttc ttgctatctt tttataatca caactctcta
      241 taatagaatt acgatttatt ttatacggct gaaaaaatct atcaccaaaa aaattcaaac
      301 attaagccaa ggattatgaa gtcaacattt cgaaaaatga acatacattg gtaagcaact
      361 ataactatta ccacagacat aaagtaacac aatatattac tatttaagtg tacgccacca
      421 gtgaatatcc tcaaggtata cagcgcacaa caaaaagaaa aaaggaaacg cagaagcatt
      481 tcctttcagt gatttaatga aaacaacacg atttgactta gagccttttt atttgaattc
      541 attttcgctt tatccaactt catttgatca tttgattact cggttaaata cttttgacat
      601 gagtatcaat gaaacattca ttaattatgg ttgcttattt cttaccgctt ttctggccaa
      661 tgctaatccg ccgattattc cggcattatc acctaattcg ggcgtaataa tgtagctatc
      721 aattggtggt atttcaacat atccatttat aagctcaaca aatttatcct gaactttttt
      781 cttcatgtgt tcttgtttca ttacaccacc gccaaaaata attctatctg gcgaaaacat
      841 cagtgttgta ttgtatgcac attgggcaag gtaaaaggct tcaatctgcc aaaacgaatc
      901 gtcagccaat aaattctggc cttttacacc caaccgtttt tcaatcgctg gtcctgctgc
      961 catcccctct aaacaatctt ggtggaaggg acagtttcct gaaaaattgt cctttggatg
     1021 tcgcttgatc aacatatgcc ccatttccgg atgactgaac ccttccacga aagtcccatt
     1081 gaacaaggca ccacctccga tacctgttcc cacagtgaag tatgcaacac ctgctaaccc
     1141 tttgccagaa ccagcaacat attcaccata gcaagccgca ttgacatctg ttgtccattc
     1201 aatcggaata ttgaaatatt gctttagcgt tcctacaaaa ttgaaatttt gccaagcaag
     1261 ttttggtgtt gatgtgatat gaccgaaact cgttgatttg cattgaatat caattggacc
     1321 aaagcagccg accccgatgc ctgccaattg ttccttaaaa ggtttaaaaa aatcaatgac
     1381 ctgcttcatt gtttcaactg gagttgttgt gggaaaactg actctttcca aaatcgttaa
     1441 ttcctcagta ccgactgcac agacaaattt agtccctcca gcttcaattg ccccatatat
     1501 catcataggt tcctcccttc gaatatgtga aaaacacttc attaacgcgg caagcgttct
     1561 cgatcagtga aatgacgttt agtatttcct gaagcttctg ttgaatacca gtaagcgaca
     1621 ctagcaacat cgtcttgccg ctcaaataag cgaacatcat cgttgccgat ttgttgtaaa
     1681 gtgaccgata aatcttcggt aaaacagatg gggtcttgaa gatgccaacg ataaagacca
     1741 tgtcgtggca ttgcgtcgtc accaaaggca tgaacggcat tcaattttcc cgtttcaaaa
     1801 cgatctcttg tggcatctct atttgattgg taaggatacc ctaaaaaggc tgttgaatag
     1861 tttttcgcat gtggacgtcc gaactcatcg tactcatgaa aggcccacgc cccgccaaaa
     1921 taatcttctg aacctgttga ggttacggtc ggatactcac tatccccatc aatgtagaat
     1981 ttaaactcgc cttcgcccca ccaataacgt tctaggcagg taagcgcaag gtaagtaccc
     2041 acgtaatagc cttgaccctt taatcgatca attaacttat aatcctcctg taatttggta
     2101 atgcgttccc gatgccaatt tgcgtgaaaa tataggctat tttcttccaa ttcgtccacc
     2161 aaagcgtaat ttatcgtata aaaaaatgag gacatatcct tcggatgtaa attctcgatc
     2221 gtaattttag cggatgtttg gaaaggcatt tcgaaatagg aattaaagcc ccctgtagga
     2281 ttaaccacta tcggcaacga gttcacctcg caacgctctc caaacccatt acaaaagaaa
     2341 tcccctaaag gactttcaac agcagggcta tccgacccat cccaataaat tcttaagatt
     2401 aaatcacgta aaacaaaact gccaaattct gttcgatcac gaatcgtcat ccacatatga
     2461 cgaattattc ccgttccagt aatatccgca atcacagttt cttcaccaga agtcagcgga
     2521 attgcgccac gacctttgcg gcttggtcct agctcgcttg gcaacatcgc agctttacct
     2581 ttctcgcctg ttggattttc gggagtgatt gctcgactct ggattttttt aaattgggta
     2641 atatttttta gtatactcat ctttttctcc tttgaatgtg aatcgttttt cccttttcta
     2701 cgtgaagaat ttttttcgta tcacttattt tcaatggctt ttctgacaaa tttgaaatac
     2761 tcaactcgga ttgcgtacat tcaatcgaaa tgaaggcttg accgaacttc aaattcttcc
     2821 aagaaaacgt taaattatca acaggatcaa tttgcaatac tccttttttg aatttcaatc
     2881 cgaaatattg actgatcatt aggctgacaa aaagacccga tgcccagccg catttgccgc
     2941 agccaaagtc tcgcacgact tctccttgtt gagcctctaa gcgatacggc caccaccacc
     3001 acgaaccgtc taaatctgcc aaacaaatta gttcttctaa tcgggttacg aaagcttgag
     3061 ggttgtgcag ctcgctcatt aaaacagtga taaagccagg aaaagtggcg ccggattcta
     3121 atccccaagt gatgcctttg atttcctcgc tataggttgg attgaaagaa ctagcagaaa
     3181 aggccatggt gttctgatat aaatgatctt tattatctaa aaattgataa aaaggcatca
     3241 acgtagtgtc tgattcttct ccatcatgca tcaataaatt aatttttcca tccacaatca
     3301 catcacttaa aaagattaac ccttgctcaa gaatcggttt ttgatagtgc ttcactgaat
     3361 aggttgtttt ctcctcatca ccgattccct ccaaaaattg ctcaccaaaa ggaccatcga
     3421 tagtcatttg tttacaaatt gattccttta gtttacaggc aatgtttttg tatcgcttgc
     3481 taagactcag ttgttctagg gcttcaaaaa tttctgcaag tccaatacag gccttccaaa
     3541 gacaaagatt gctgccggta tgatactttc caagtgcaaa ggcgtctgat aaccaaacag
     3601 atggaaaaag cattggttcc cctgaccgac gttgagctaa tatgtcctca ataattcttg
     3661 aagcattcag tagaacctgc ggacaccgct caaagaattt tgtatcccca gtatgttcaa
     3721 aataaagact agccagtaac gcactggata acgaattact cagagaatga ttgatacctc
     3781 ctgtaaattt tgaaccagga aacttaacgc catattgatc aaaccataga accgtttttt
     3841 gacataactc cggttcaaac atggtgaatg gcaatgatgc gtaatacata tccttattcc
     3901 aaattcgatt agtagcagga tagctgcccc aattgctgcc gacgacctgt ccctgtcgat
     3961 tcataccgaa actagaaaag ctttgataaa gtgcacgacg atagagatgg acaactctat
     4021 cgtttggcat tgacagctgc ccaaatagct gagcaaaata gttcaatgtt tccttcagcc
     4081 atttttcgat atcagattcc tgaaaagtca ttacttcttc aaaagcattt gggtccacaa
     4141 aagcaatggc gaagcttgcc acttcctgtt gtgcgatcgt gtccttattt cctttttgag
     4201 aaatcaacac attttgctga tccgaatact tctcttgata cgaaggcaca tctttcactg
     4261 aaacttgaag gctttcgtgt gtttcattca caatgtaaac ctgttgaaca agcatactta
     4321 aacgcttatt agccagtatg ggagcaaagg atactacaat gaccttaaac gtcgaataat
     4381 gatgaatata tctaggcaaa cagtcttgaa tcacatcgac ttcaatacga tgatccgatt
     4441 ctgacaaatg gtagacaatc ccgtttactt caacctttaa ggataacgaa ttggtttgag
     4501 agagctgttt attgacccaa acacctggtt tttcctcagt tagtaaattt tctcgataaa
     4561 aggtcaacgt ttgaatcgtc ccgcaaacat caaggtttgc taatgtcttt tgattactta
     4621 catcgaaggt caatcccttt acatcaggaa tattccgata gtagctgtat tcgtttgaag
     4681 tagtcacatt tccgtcgttt aactcagcat taaaaaatgg gtgtttgggt gaataaatta
     4741 cttcattaat agtcatcttt tccctccttg ctaaaaaaac tgcagcctag tagctgcagc
     4801 ttcctactat gcgattccaa gtaatgacaa taaaattccc aagacgacca ttccaaaaat
     4861 aattttgatg acgccgactt ttttatctag taatttgaaa cagctcaatg ttaccaataa
     4921 cggtacaatt cctttaaaaa tactatcgag gatttcttgg acattcatta gttcttcgcc
     4981 cttcattgaa aagctcaaaa cggtattgaa tttgaccata ctgatcgtca ttgcacctac
     5041 catgatcaga cccaagatac tagcagcttt tgtcagaatt tcaattaacc cgttcgcata
     5101 cagcttttca atatatttag agcctaatga atagcctaaa acgccgccat agtatcgcat
     5161 caagtaatta ggtatattga acataactaa aaagataatt ggtgccaaaa tatttccggc
     5221 attggctaag ttgatcgcta gtcccgcggt aacgacacgc caaactcccc agaacaatga
     5281 atcgccaatt ccagccaatg gtcccatcaa actcgttttg atcgcgttga tactttccac
     5341 gtcaaaacca gctttttcag aattttcctt ctccatcgat gccgcaatcc ccatgacaaa
     5401 ggacgcgcaa ggaatggtcg tcgaaaaata ctgtgtatga cgttccagcg ccgcagctcg
     5461 atcttcttca cttttgtaga aatgattaat gaagggcatc atagaatagg cgaaaccacc
     5521 gccgcccatc gtcaccggat tcaccgaagc atacatagtc atcgagcgcc aaaacatctt
     5581 ccgaaccaat tttttctcat ctttagaaat tccatcagct aatttcattg aaagaaatcc
     5641 tcctcttctt ggtcaagcgt tgcatttaca gcagcatcgc tttgaactgc atgaacagat
     5701 atatttttta gttgtagatc tctttgggct ataacaattg caataatcgt tccaactgcg
     5761 gcaattgcaa tcaatggtaa ctcgagatac gccataacaa cggccccaaa gaaaaaccac
     5821 acagcaatat ttttactcca aagcatccgt aacagcatcg ccatcccaac tgccggcagc
     5881 agatttccag cgactgttaa tccgttcatg atgacctctg gaatattatc caagacgctt
     5941 ttgacaacat ctgctccaaa taaaacggca aagaatggaa taagagcata aagcgcatag
     6001 tggacaaacc acataaagaa gtgcagattg atgattcctt tttgatcacc agattttgca
     6061 aatttgaaaa atttagcagc catcggtcca catacaaaag aaaaaatcat attcattaac
     6121 tgtaatccta atactgctag tggaaagaca atgggaataa tcgcatccac gtttcctccc
     6181 attttgattg cgaacgctgt agccagccca gcagccaaag aaggctccgc cgtactagag
     6241 attccgatat tgacgacacc cataaagatg gcttctagtg acgccccgac aatcaacccc
     6301 gtctgcaaat cccccatcaa cgctcctgct aacggagcaa caacaatcgg acgactcagc
     6361 atggacatcc cgaacatttc atgtccagca actccaataa aaacggccaa agcgactaca
     6421 aatgcatcat acataatttt tctccttcct ttttctaaaa atcactcaaa atagagatag
     6481 ctgaacgttt ttccatcgcc ggtgtaggct gaaaaacggt atctggataa agttcaacta
     6541 attcttttaa gtcttgaatt tctgacgtcg ttaacatcac ttcctttgat aaggttttct
     6601 tatcttccga tggcggtgtc attttcccag cattccccac gttcattaat tcgatttccg
     6661 ttgggaaagc tttcgcaact tttaccgcat ctttgacatt agggactaaa accatcaagc
     6721 gcatgtcctt cgcccgcgga tcttttaaca aatgaatcgc gtcatcaact gttttaataa
     6781 tgactttgac attcgatggt gcagccatct tcaatgtcat cttttgaata tcgttggtag
     6841 ccgcctcatc gcttgctact actaacccgg ttaaatttag actctttgtc caagtcatcg
     6901 ctacttgtcc atgaattaat cgttcatcaa ttcgcactgc tttaatcatt tttcttcctc
     6961 ctaaaaaaaa tcttcctctt catttactac atgtacctca tcaagaatgg tcatctttaa
     7021 ttcctgttgg catttattta ccagttcctg aatatcctcc tttgttaatt ccttggttgc
     7081 caatactatt tcgagcagaa ttggcagatt aaagccagac aaaatagtta cagcaatctc
     7141 tttctccaaa aaggttttgg taatcttctg attgacactt ccgccaaata aatcggtaaa
     7201 aacaaaaatc tgatcctgct cgttcacctg gtttacaaat acattcaact cctgttcaaa
     7261 atcacactca tccacataag cattaatcac cgtaatctct tgaaccttcc ccgtcagtaa
     7321 ttgaatactg ctaagaaagc ctgaagctaa gtgaccgtga gtcgctatta gaattttctt
     7381 catatggtta attcctttct ttctgttcac ttttatataa gcaattcctg tgccaacttt
     7441 taaaaacatt ggtttaatca cgttaattca cattaaaaaa agtgtctaac cta
//
LOCUS       DAXQKX010000097         6944 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.100, whole genome shotgun sequence.
ACCESSION   DAXQKX010000097 DAXQKX010000000
VERSION     DAXQKX010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6944
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.100"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..1059
                     /locus_tag="ACF3MF_002630"
     CDS             <1..1059
                     /locus_tag="ACF3MF_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HFE3928532.1"
                     /translation="PDWLIDYAEKEGLIAELKPKHERQNFLVRDDRLDHAVAFLWKDP
                     QTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFNLKIGDPKQLKFFESSIDL
                     LSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRKKQAFPQSIEICVDNDRAG
                     HIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPREYKVIYEEVAKEEKVTPEAIMAI
                     HKTENNLQLTNQLVSAHKVNASFGQQLSVNDSIEVISLKDICREVAKELKDCERSNGT
                     YDFDRFYQGKGDINSQILFSYKAEQYYKGYKNHEHEFVPEVKKDWNDQLKHEIHQQEI
                     RKQKRAMLFQQGRQQERE"
     gene            1070..3274
                     /locus_tag="ACF3MF_002631"
     CDS             1070..3274
                     /locus_tag="ACF3MF_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HFE3928533.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFSGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFNVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQAGADQGKTFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVTAQNGIFDAKLDPNETQATQEAFEAYLKEKGVQVGKQPGTILEVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EHAYLLDHLDEYKHFLKAESFPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTEATYEK
                     LTPLQQAIYDQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAVGKVPVDLGWKKLFGK
                     ESDRKEKEEEPLLPKVTKGETVTVDLQIFEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLTKIGEQKGTQATFLANIQKFVSHLLEVVPGQIQATDFGATLQEVKV
                     ASEKQEAARHLGSCPKCQEKEVILYQKVATCTSEACDFKLWVTIAKKKLTATQLKEII
                     QNGRTSQPVRGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTTYKRKVRRKTS"
     gene            3295..3444
                     /locus_tag="ACF3MF_002632"
     CDS             3295..3444
                     /locus_tag="ACF3MF_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928534.1"
                     /translation="MRNTTHKEQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     LELDR"
     gene            3520..4113
                     /locus_tag="ACF3MF_002633"
     CDS             3520..4113
                     /locus_tag="ACF3MF_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HFE3928535.1"
                     /translation="MKDKVKCIFEKYNGNLSLKDARNEGLSPMTLDRLAEKDKIEKIA
                     SGFYTLKDSFVDELYLAQSIYTRGIFSHETALDLFQVGTYIPKKINMMFPKGYNVSKE
                     NLDQYAIQPHYTNKENFELGITEAESFYGNKIFVYDLERTLCDMWNPRYKASVEVKQE
                     ALKEYMTSTSRNTNKLRRYMNILKSPKEMTLYMLPLY"
     gene            4129..5028
                     /locus_tag="ACF3MF_002634"
     CDS             4129..5028
                     /locus_tag="ACF3MF_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HFE3928536.1"
                     /translation="MTPTQFKAKTRNVAAEKHLNPQIVQRYYMMEKLLECIVESPYHD
                     DFVLKGGFLIGSKYGLENRSTVDIDTTYRNSKLTKEKLETVFSELTAAPTKDGIRFEL
                     KGLTETREADYYPGFQAKFIAFLENARVPFKLDITSGDSIIPAALIYEHKLMFEDKTI
                     HIPAYPTEQILAEKLHATFSFGIDNSRMKDFYDLYMIPKLERIDEINLYKSVQGTFKE
                     RNNQSVFKNLYNQEMPQLMKNEGLREKWKRYQQENYFAKDISFESTLTSVDSLMQSIV
                     EQEEVERKQNFKRSQQMNQEMER"
     gene            5031..5516
                     /gene="ssb"
                     /locus_tag="ACF3MF_002635"
     CDS             5031..5516
                     /gene="ssb"
                     /locus_tag="ACF3MF_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFE3928537.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVTTFTLAVNRNFTNQSGNR
                     EADFINCVIWRKPAETIATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRMHADQSSSSPSPTTFEQRDTATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            5882..6142
                     /locus_tag="ACF3MF_002636"
     CDS             5882..6142
                     /locus_tag="ACF3MF_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928538.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            6583..6789
                     /locus_tag="ACF3MF_002637"
     CDS             6583..6789
                     /locus_tag="ACF3MF_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HFE3928539.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
BASE COUNT         2503 a         1212 c         1431 g         1798 t
ORIGIN      
        1 cccgattggt tgattgatta tgcagaaaaa gaaggattga ttgccgaact aaagccaaaa
       61 catgaacggc aaaatttctt agttcgagac gatcgtttgg atcatgcggt cgccttttta
      121 tggaaagatc cacagacaaa agagacagta ggggcgagtt atcaaggaac gttcattgat
      181 tatgaacgtt ttggtgagag aggcacatat aagcatatag ataaaaattc gacagcgaat
      241 catggcttta acctaaagat tggtgatcct aaacagttaa aattttttga gagtagtatt
      301 gatttactta gctacgctgc actgaatcgt gatcagttaa acgatacgtg gttagtctct
      361 atggaagggt taaaacacca tgtgatcagt cattattttg gtgaggcagt atctgaattg
      421 agaaagaaac aagcctttcc tcaatccatc gagatttgtg tggataatga ccgtgcagga
      481 catattttct acgaaaaaga acaattaatg ggcgcagttg atccatttac gaatcagaaa
      541 gtacgttgtg aacgaggaat cgctaatgat tggcaagtgc caagagaata caaagtcatt
      601 tatgaagaag tcgcaaaaga agaaaaggtc acaccagaag ctattatggc catacacaag
      661 acagaaaaca atctgcaatt aacgaaccaa ctggtttccg ctcacaaagt caatgcgtct
      721 tttggtcagc agctttctgt taacgattca atagaagtca ttagtttgaa agatatttgt
      781 agagaagtcg caaaagaatt aaaagattgt gaacgctcga atggtacgta tgattttgat
      841 cgtttttatc aaggaaaagg ggatattaat tctcagattc ttttctctta taaagcagaa
      901 caatactaca aaggctataa aaatcatgaa catgaatttg tacctgaagt gaaaaaggat
      961 tggaacgatc aattgaagca tgagatccat caacaggaaa ttagaaagca aaaacgtgcg
     1021 atgttgtttc aacaaggcag acaacaagaa agggagtgag atcgtcacga tgaaaactgt
     1081 cattttagca gaaaaaccgt cacaagcgaa ggcctatgcc gatagctttt ctaaagccac
     1141 ccgaaaagac gggtattttg aaatccaaga tcgattgttt tcgggtgaaa ctgtgatcac
     1201 gtatggtttt ggtcatttag tcgagttaga ttcgcccgat atgtacgatg aaaattggaa
     1261 acaatggtca ttagagcatt tgcctatttt ccctacacat tatcactatc atgttcctaa
     1321 agataagaaa aagcaattca acgtggtgaa acagcaactt caatcggccg acaccattat
     1381 tattgcgaca gatagcgatc gtgaagggga actgatcgct tggacgatca ttcaacaagc
     1441 aggcgctgat caaggaaaaa cctttaaaag actttggatc aactccttag aaaaagaagc
     1501 catttatcag ggattccagc aattacgaga cgcagaagag acctatccca aatttgaaga
     1561 agcacaagca cgccagatcg ctgattggtt gatcggcatg aacggcagcc cactgtatag
     1621 tttactcttg cagcaaaagg gcataccagg aagtttttcc ttaggcagag tccaaacccc
     1681 aacgctttac atgatttatc agctgcagga aaagattaga aacttccaaa aagagcctta
     1741 ttttgaaggg aaagcccaag taaccgctca aaatggcata tttgatgcga agcttgatcc
     1801 caatgaaacc caagcgacgc aagaagcatt tgaagcctat ttaaaagaaa aaggtgttca
     1861 agtaggaaag cagccaggca cgattcttga agtcgaaacc gagaaaaaaa gcgcggcaag
     1921 tccacgtctt ttttctctat ccagccttca gtctaaaatg aatcagctca tgaaagctag
     1981 tgccaaagat actttggaag ccatgcaagg gttgtatgaa gggaaatatc taagctatcc
     2041 acgaacagac accccttata ttacagaagg agagcatgcg tatctgttgg atcatttaga
     2101 tgaatacaag cattttttaa aggctgaatc attccctact cctattcata caccgaatag
     2161 tcggtatgtg aataataaga aagtccagga acattacgcg atcattccta caaaaacagt
     2221 tatgacagaa gcaacgtatg aaaagctgac acctttacaa caagcgattt atgatcaagt
     2281 tttaaagacg acggtggcca tgtttgcgga aaaatatacc tatgaagaaa ctacgatttt
     2341 gacacaagtc cagcagcttc agctaaaggc agtcggaaaa gtaccagtag atctaggttg
     2401 gaaaaagcta tttggcaaag agagcgacag aaaagagaag gaagaagaac cgctacttcc
     2461 taaagtaaca aaaggagaaa cggtgacggt agatctacaa atctttgaaa aagaaaccaa
     2521 gccaccacaa ccttacacgg aaggtacact aatcaccgcc atgaagacag ctggtaaaac
     2581 cgtggatagt gaagaagcac aatccatatt gaaagaagtg gagggaattg gtacagaagc
     2641 gacacgagca aatattattg aaaccttgaa gcaaaaggaa tatatcaagg tagagaaaaa
     2701 taaacttgtg gtgacgaata aaggaatttt gctttgtcag gctgttgaaa aagaaccgct
     2761 gttaacaagt gccgaaatga ccgccaaatg ggaaagctat cttacaaaga ttggtgagca
     2821 aaaagggaca caagctactt ttctagcaaa tatccaaaaa tttgtttccc acttgttgga
     2881 agtcgtccca ggacaaatcc aagccactga ttttggagca acgttacaag aggtgaaagt
     2941 agccagtgaa aagcaagaag cggcgcgtca tttaggatct tgtccaaagt gccaggaaaa
     3001 agaagtcata ctttatcaga aggtggcgac ttgcacgtct gaagcctgtg attttaaatt
     3061 gtgggtaacg attgccaaaa agaaactcac agcgacacaa ctgaaagaga tcattcagaa
     3121 cggccgaaca agtcaaccag tcagaggact aaaaggtcag aaaggttcgt ttgaagcaac
     3181 gatcgtttta aaagaagact ttacaacagg atttgagttt tctgaaaaga agaagaccac
     3241 ctacaaaaga aaagtgagac gtaaaacgag ttagaattga cggagggaaa aacgatgaga
     3301 aatacaacgc ataaagaaca agaaatcgaa aatcaaaaag ccaaaatacg ttcagagcag
     3361 gagaaaatgc gtgccagcaa acgaagacta cagcaattga agaatcaaca acggattcaa
     3421 aaagaacttg aattagatcg ataaatcctc ctgttgttaa tattaaacta acatgttata
     3481 gttatgttag tttaatatta acattcgaga gggaaagcga tgaaagataa agtcaagtgc
     3541 atttttgaga aatacaatgg taatctatcc ttgaaggatg ctagaaatga agggttatca
     3601 cctatgacgt tagatcgttt agccgaaaag gacaaaatag aaaaaatagc atcaggtttt
     3661 tataccttaa aagatagttt tgtggatgaa ttatatctcg ctcaaagtat ctatactaga
     3721 ggaatcttct ctcacgagac agcgcttgat ctttttcaag taggaacata tatccctaaa
     3781 aaaattaata tgatgtttcc taaaggatac aatgtttcga aagagaattt agatcagtat
     3841 gccattcaac cgcattacac gaataaagaa aactttgaac tgggaatcac agaggcagaa
     3901 agcttttacg gcaataaaat tttcgtctat gatttagagc gaacgttatg tgatatgtgg
     3961 aatcccagat ataaagcaag cgtagaagta aaacaagaag cattaaaaga atatatgaca
     4021 agtaccagca gaaatacaaa taagctaaga agatacatga atattttaaa atcaccaaaa
     4081 gaaatgactt tgtatatgtt gccactttat tgagaggagt aaaggtgaat gacaccgaca
     4141 caatttaaag cgaaaacaag aaatgttgca gctgagaaac atttaaaccc acaaattgtt
     4201 caaagatatt atatgatgga aaaattatta gaatgtattg ttgaatcgcc ttatcatgat
     4261 gattttgtat taaaaggggg atttctgatc ggatcaaaat acgggttaga aaaccgttca
     4321 accgttgata ttgatacgac ttatcgaaat tcgaaactaa caaaagaaaa attagaaact
     4381 gttttttctg aattaacagc tgctcctaca aaagatggca ttcggtttga attaaagggc
     4441 ttaacagaga cgagggaagc cgattattac ccaggttttc aagcaaagtt tattgctttt
     4501 cttgaaaatg cacgtgtacc ttttaaatta gatattactt caggtgattc tattattcca
     4561 gcagcattga tatatgaaca taaattgatg tttgaagata aaacaattca tattccagct
     4621 tatcctacgg aacaaatttt agctgaaaaa ttacatgcca cgtttagttt cggaatagat
     4681 aattcacgta tgaaagattt ctatgatctg tatatgatcc ctaaactaga acgtatcgat
     4741 gagataaatt tgtataagag tgttcaagga acatttaagg aaagaaataa tcaatcagtg
     4801 tttaagaatt tgtataatca ggaaatgcct caattgatga agaatgaggg attgagggag
     4861 aaatggaaaa gatatcagca agaaaactat tttgccaaag atatttcttt cgaatctacc
     4921 ttaacttctg ttgattcgct gatgcaatca attgtcgagc aagaggaagt agaacgaaaa
     4981 caaaatttta agagatcaca acaaatgaat caagaaatgg agagataaag atgatcaata
     5041 atgtaacttt agtaggtcga ttaaccaaag atcccgattt acgttacacc gcaagtggca
     5101 ctgcagtgac cacttttacc ttagccgtta accgtaattt tactaatcaa agtggcaatc
     5161 gagaagctga ctttatcaat tgtgtgattt ggcgcaaacc agctgaaacg atagcgacat
     5221 tagctaaaaa aggcagcttg atcggcgtcg tcggacggat tcaaacgcgg acttatgaca
     5281 accagcaagg acagcgtgtc tatgtgactg aagttgtggc cgataatttc caactattag
     5341 aaagtaaagc agcgacagaa agccgtatgc acgctgatca atcgtccagc agtccaagcc
     5401 ctaccacctt tgaacaacgg gatacagcga cgcctaacaa caatggattg aacgcttcac
     5461 agaatccatt tggtggacaa tcaatcgata ttagcgatga tgatctaccg ttctaagtag
     5521 cattttctat tggttgcatt tgctacggtt tatgttataa tttagacaac aaaaagaatt
     5581 ttcaatctat aaccaaaaac cactagctgg cgggctagtg gctttctttt acgtttctat
     5641 tataagaatt aacgggtagg cttactgtct ttcttggcaa atttacaatc aagccatttg
     5701 cagatatagt gcgcggctac ttctgccatg attgcaaaaa caaaatcaaa aagaattttc
     5761 aaacctataa cctcctcccc ttgccagatt aggccggggt agcagacagc aagactatta
     5821 tagcataatt gaaatatcca aatgattgga tttttgctat aattttagcg aggtgattgt
     5881 gatgaacaaa tatgttggtt tgcttgataa aatccgagta ataaaaacgc aaccgttatt
     5941 ggttcgcttt actttacaaa cgattcatga atcgattaat tgtgtagttg cagatattga
     6001 aattatcgat aaattgctaa ttatggatga tggaaaatac aatattgccg tcacaggtca
     6061 cttcaataaa cgaaatcagc tagttattgc tagcatgtat gttagaaatc ccgatcattt
     6121 tacgcgatcg atgggcatat aaataaaaga agagttgtag tcctaaatga ggattgcagc
     6181 tctttttgtt ttacatagaa acaggaaaag acctttttag gaagacacaa gtgccttctc
     6241 aattgaaaaa cctttctctc actccaaccg ccaccgccgt tcgagaagaa aggaagtgaa
     6301 cgctgcacgt tcactaagat atggtgtctt gcaaagcaag acaaaataga caaaacttcc
     6361 tctcaccaaa aggttcgttc ctgttcgtta tctctttatt gatttgccag accggcaaca
     6421 agttgccttt tatcaccaaa aagcgacaag gacaagggta aatggcacgc tgcgcgccct
     6481 tgtccttgtc gcttttcgtt gatttattct ggccaacaaa tcaataaaga aagaactaac
     6541 gaaaggaagt aaaacctttc ctaagaggag gcagaatcaa acatgcgaaa gaaatttgat
     6601 tattggggtg ttcccttcag cgaattattc ccaaactatc atgcaccaca tactgttgaa
     6661 tgcgattgtg gagaaagagc gaaatgtatc aaaagctatc gtttgtatca atgtccaaca
     6721 tgcgggaaaa aatatacctt gtcttatggc gattacattt tgattgatga gaaaggaaag
     6781 aaacgctgat gaaaacacaa cacaaattat tgactgtaaa agaagtcgtt caaattttgg
     6841 tggacaaaga agtcatttct gaaaaagtag cagaagcttt acttattccg cggtactgga
     6901 cgatagaaac ccctttagta gaggatgcac cgactatgct attt
//
LOCUS       DAXQKX010000098         6863 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.101, whole genome shotgun sequence.
ACCESSION   DAXQKX010000098 DAXQKX010000000
VERSION     DAXQKX010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6863
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.101"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(366..683)
                     /locus_tag="ACF3MF_002638"
     CDS             complement(366..683)
                     /locus_tag="ACF3MF_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFE3928540.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTIHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQIK
                     LGF"
     gene            complement(684..938)
                     /locus_tag="ACF3MF_002639"
     CDS             complement(684..938)
                     /locus_tag="ACF3MF_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFE3928541.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDTIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            complement(1198..1422)
                     /locus_tag="ACF3MF_002640"
                     /pseudo
     CDS             complement(1198..1422)
                     /locus_tag="ACF3MF_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877485.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(1975..2061)
                     /locus_tag="ACF3MF_002641"
                     /pseudo
     CDS             complement(1975..2061)
                     /locus_tag="ACF3MF_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            3227..4267
                     /locus_tag="ACF3MF_002642"
     CDS             3227..4267
                     /locus_tag="ACF3MF_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HFE3928542.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESGISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYE
                     SSPSTITKDWLE"
     gene            5091..5423
                     /gene="traE"
                     /locus_tag="ACF3MF_002643"
     CDS             5091..5423
                     /gene="traE"
                     /locus_tag="ACF3MF_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraE"
                     /protein_id="HFE3928543.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
     gene            6042..6383
                     /locus_tag="ACF3MF_002644"
     CDS             6042..6383
                     /locus_tag="ACF3MF_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
                     /protein_id="HFE3928544.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     NEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSV
                     EIIEFVADKEE"
     gene            6402..6692
                     /locus_tag="ACF3MF_002645"
     CDS             6402..6692
                     /locus_tag="ACF3MF_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928545.1"
                     /translation="MKFFEVKSPYYYALIAAKNEEECAELYEQVVTDIENREEFIRCL
                     HELNRNEAIQEDAKKISEETLQPIGMEEATKDIFTIIDEQKSCVLSIDSTLV"
BASE COUNT         2440 a          999 c         1137 g         2287 t
ORIGIN      
        1 aaaataaata ctaccttatt taggtagtat ttattaaaag ttacgtcaat tttgattaaa
       61 aatatactac ttgaacctct catgagtaaa gtcacgaaat ttttgggaat agagcgtact
      121 tgatatctta ttttttcact aatagcagtg tctcttattc accaagcgat ccccgtagtt
      181 cctacggttc ttaatttttc tctagaccaa tgattgtatc tttagacctt cggccataac
      241 atggagcaaa ataaaaaggt actaagtctt atatatcaat cttcgagtaa ccgacggtta
      301 acaaccatat cgagcggcat taatcaccca cctgtagagg atgagcgact tttgcctaat
      361 tattgttaaa agcctagttt tatttgttta gattggaaaa tacgtcctac aagtatctct
      421 tttttttcat ggtcgatccg ataaaataag gcatagcttt tgccgatcac gatccgatat
      481 gttgggatat ccattccata gatttcggaa acttcctcat gtatagttgg aaaatttttg
      541 gttagttcta aagccttctg gatcgcacct acaaatcttt ttatgctggc tggagaaaga
      601 gcaagctcat tttcccattc ttctattatc gtttcaaggc tggtctggaa acttttagaa
      661 taaactagcg tgtactcttt catctattca ctccagccgt attttccgaa agcttttacc
      721 atttcaattt ctgaaactgt taaacctttc tcaaagtctt ggaaactttc ttcaatcaat
      781 ttgcgatcgt gttcttttgc tatttgagta gtatctaata tgaataagtt gccttcttgt
      841 ttggcttgga tagtgtctcc gctttttaat ccaagagagc ttggaaggat cactcccacg
      901 ctattgccga tctttctaac ctttagttct tttcccatgt tatcacactc cttttagttt
      961 ttgatgaata aattataaca tgttataaca acaattgcca acggtgtttc ttaagggatt
     1021 ccactccata ttattattgg acaaaataag ccacttagaa cgctgaaaac atatacaaac
     1081 gatatcaaaa tacgagtgaa ctactcacca tacacttccg ttaacatcca tttaagtagg
     1141 tatttttatt atatatagat ttaacatatg tcggtcggtt gattgatata gctaaagtta
     1201 taactcaacc gaagccgatt catctacacg aataaagttg cgagtgttct cggctaattc
     1261 ataaaaattg ttatgtgttc catatagcaa tactggaata actttatttt cttgaatctc
     1321 ataagcaact ctatacacgg tgaccgcata cttaaatcca ttagaccaat tacctgataa
     1381 acctccagtt ttttgctctt acttaaatgg atcaatagca atttcatcac aaacctatag
     1441 aggatgagtg acttctgcct aattacgtta aaaaatattg aaagtaactc tatgtagcaa
     1501 aaaatatcta gaatttcatt tcctcaaaac tgatcgatat tgtatctaaa aatatatact
     1561 acctaaaata ggtagtatat attaaaatat gtgcttttgt tagaaaaatc aatacataaa
     1621 ttatcatatc tgtatatgtc atttaggtat ttcagttatg ttataatagt tttgctgtct
     1681 gctaccccgg cctaatctgg caaggggagg aggagatata atgaaatacc tttttgattt
     1741 tgtttttgca atcaagccac ttgcagatgt agtgtgcagt tacctctgca aatggcttga
     1801 ttgcaaattg ccaaaaaaga cagtaagcct acccgttaat tctataatat agaaacgtaa
     1861 aaaaaacccc atcatcctgc acgctgatgg ggtttggtga tataatgaaa tacctctttg
     1921 ttactcataa ttataccata attagtcacg aatgcaacca atagaaaaaa ctacttagaa
     1981 cggtagatca tcgctaataa caatgcattg tccaccaaat ggattttgtg aagcattaaa
     2041 tacattgtta ttaattgtcg ctgcttttaa ctaggcctct ccccttctat tataaaagaa
     2101 gatatatatc atttcttaat tacctactac cttaaaccaa aatttaagta ctacctaatt
     2161 taagtagtac ttaaacaatc taaaaaatag ttatcccaat tgttatgctt ttataatacg
     2221 attatttgta acaaaatgaa tattatataa ttaaacacta ccatatttag gtagtgttta
     2281 attattagca aaacaaaaaa tatttattct attctcttaa cttcaactaa gttatgctgc
     2341 acacctttat ataaatcata tgcaactcat tagctagaca aactacaagc atgtagtttt
     2401 atctgttaat tatgtactac ctaaataaag tagtttataa ttaacaagta tatatattta
     2461 aaaatttaag attaattttt ttatgacttg tacaaattta tctgatattc tcttattaag
     2521 aactacctaa tttgggtagt tcttattttt tacattttaa gtagtattta attgcaattt
     2581 ggtagtattt ttttattatc ttattcttag aacggtagta cttaatataa atataggtag
     2641 tatctaattt aagtattaat ggtagtatct aaattaacag gtagtatgta actactttaa
     2701 agtatttttt ttcagattaa cacagtagta tcttattaaa taagttaatt ttaatggtag
     2761 tacataatta ttatatatat ctgacattgg tagtacttat tgtatttttt agtagtatat
     2821 aatctattgt tttctaacct aaagccttgt cttataagaa taatataata tatactactg
     2881 aaataaggta gtatatattg ctagtaatgg tagtatgttt tatatgcata aggtagttct
     2941 taatttattt tttgttttga cactggtagt acttaattat ctttaatttt aaaactaaat
     3001 tttattcata cgttcttctg gtagtattta attataaata atatttattt aaagtagttc
     3061 ttaatgactt taaaggtagt acataattca ttttatttct gattttaggt agtatttaat
     3121 taaaaaacag ttttaatgcg tttgcatttt ttatttatct ttgctatttt cgaaaagagt
     3181 aggtaatttt acataaataa aacaacgtga aagtagagga tctacaatga ctgattttaa
     3241 attttttaag gcggatagag tttacaacga attattttat caatttccaa aagtctttat
     3301 tgtttctgac gaatacaaaa aaatgaaaga ttcaactaag attgcctata tgcttttaaa
     3361 agcaagatta gagatcgcaa tcagcaaacg gcaaatcgat gaagaaggta atgtttattt
     3421 tacttatacg acaaatgaac tatgtagagt attaaactgc caaaaacaaa aagcgatagc
     3481 aatcaaaaaa gagttggaat cctttggttt attattacaa aagcagatgg gatttaacaa
     3541 acagttaggg aaaaataatc ctaatagact atatctagca gaattaaaag tctcagaaaa
     3601 tgatatctac ttactcgaaa aatttgatag agagaatagg gaaaacgttg ataaatcaga
     3661 gggtatgaaa atcataccca ccctcgacga aaaatcagac gctgaatccc ttggggctca
     3721 agagggtatg aaaatcatac cgtgccaaaa cgttgataaa tcagagggta tgaaaatcat
     3781 accagaactt aataataata tattagacac taatagacac aatatagaca ctgaaaaaga
     3841 ccgcctacaa gatcaattgt tgttagacaa ttttgagaca attatgacaa acgacagcat
     3901 tgctacgttt gtccctgaac gagtattaaa tttgataaaa acattttctt caagttacag
     3961 tgaagctcaa aaaaccgtcc agactattca taatgcaaag aaaaaagctg aaatagaaag
     4021 tggtatttcg atagtttttg aagaactcga tagttattat gtcaatgcag aacaagaatt
     4081 atacacgaca ctgttaaaag cctatcaaaa attaaaaacc gaaaaagtcg aaaatatcca
     4141 gaacctgatt tttgtctatg taaaaaattg gtttatcgaa aaaccaatag ctgctaaagt
     4201 atcaagtgaa aaacgtttga attatgaaag ctccccaagc actattacga aagactggtt
     4261 agagtgaaac tttactgaca aagtgattgt tgcttcatga agtaacatta aaattaaaaa
     4321 ttttttatta ttctaattat attacgaata ttacaaaata atagctattt taatagaatt
     4381 tataagttaa aatattatga taaaaatcac aaacgtagcc ttttacgtca taagtgttaa
     4441 aagaaataat taatttcaaa tatagaaaag ggaacgtatg tttgcatact cctttttttt
     4501 gagttataat aatacgcgaa gagagataat ttcattattt aaacaagcta aaaatcttga
     4561 tattacttct tttcaggcaa tacgaatatt attcgcttac attttttgta taaatttaat
     4621 tgtctgctat gcttgtgatg aattgatttt cgttctgcac ttttggatga taaatttgga
     4681 caattgaaaa tacaaaaaaa agaaaggcgg tatgaactcg gaaggctggt aaccttcgtc
     4741 agcgttcata cacggcatta agatttggcc cttaatgcgt taacctttca gtgttacggt
     4801 attacccgca atggatttag tataacagat attcaaaagt gataccactt tttttggctg
     4861 tgttaaggtt aaaaatacgt gatattacga tgaatctatg cctaagcata atgttataaa
     4921 aatgtccgtg tggctctttg ccgtatgacg aacgctgaaa ttagagggaa cgcatgtttg
     4981 gatgcgttcc ctcttttttg tttgtcatga acgaaaatca attctctatt tttgaaaaat
     5041 aacaagaaaa acttgttaaa aatatttaaa gaaattgggt ggtttatttt atgtcatata
     5101 caggaatttt gagtctcaaa gatatttgtc actacggtaa acggtgtacc gctacagaga
     5161 aaatcacgaa gaaactatca actggccaaa gtaaaaccgt tgtgcagtgt aagaaatata
     5221 taatccagaa agacaaagtc tcagaggaaa tgatttatta cattgggaaa caaaagcaaa
     5281 taattttaaa agatcctatc cccttaaaag agctatatcc aacaatcaaa catgtttatg
     5341 accaaaacgg tgtactgatt ggtcgaagaa aaaatggagt cttgcgttgt accgcaaaag
     5401 ggatggggcg tttaatcagc tgaattgatc attctcataa cttgtatttt atcgtttttc
     5461 gcttgcttga aaatattgtc gagacttcta aaagaactta gaatcattag aaaaataagg
     5521 agtagacttg atctatcaac aatttccttc ggggagtgac ggggtagatt tttacgattg
     5581 gtaacgtaaa aaattggtca atcgagtaaa tgcgcttgtt tggatagtgg tgaaatgaat
     5641 ttgtgtaaat aatatacaca gagtaaacaa gagggaattt agaggttaga caagttagaa
     5701 tagcgcctag attaatcatg agcagctact aagggatcta ggctttgacg caaactcatg
     5761 gaataaggag taggtcttct cgtaatgggg aggacgcaca agaaattgtg tcgtgtgctg
     5821 cagtacatgt agatacttgc gaggacgttg gtcattggat caatcgagca tttaccgctg
     5881 tctactaggg tttctcgttt cggacgccat aaacgagtcg atatttttta tgtattttta
     5941 agtaaacgaa aaacgataaa atatgaacga gtcctgaata aagtgaaaaa attgatataa
     6001 aacatagaga aaatgaaatt tacgtaatgg aggaatgaca aatgaaaaat tatgatccga
     6061 atatacgatt gggcacacat actattaagg tttctttcca acgttgggat tacaaaggtt
     6121 ttgtgacgtt tagaagaggc ggaaattgta aaggattaga tgttttagca ttaaacgagg
     6181 atgatttata cgatcaaaca ttgactgata atccaattgg attcggcttg ctacctgaag
     6241 atgatgaagg taatgaatgg tttaaaatga cgcttatgaa tgataatgga gacgaattat
     6301 ctgttgaaga tacttggtca tatttgagtg attatattgt cagcgttgaa atcattgaat
     6361 ttgtagcgga taaagaagaa taaaaactgg aggaataaat tatgaaattt ttcgaagtaa
     6421 aatcaccata ctattatgcg ttaatcgcag caaagaatga agaagaatgt gcagaattgt
     6481 atgaacaagt agtaacagat atcgaaaatc gtgaagaatt tattcgatgt ttgcatgagt
     6541 taaatcgaaa tgaagcaatt caagaggatg cgaaaaaaat tagtgaagaa acgttacaac
     6601 caatcggtat ggaggaagct acaaaagaca tttttacaat tattgatgaa caaaaatctt
     6661 gtgtattaag cattgattct acattggttt aatagatcca agattctata atttttttca
     6721 aagtaaaaag aaattaggta atgattctca gaccaattac ttaggaaaat aaccatacaa
     6781 attagatttt acagataaag gattagaagg aatcacggcg attaataaaa aggtagtatt
     6841 accttaggca ttgagtaagg aat
//
LOCUS       DAXQKX010000099         6602 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.102, whole genome shotgun sequence.
ACCESSION   DAXQKX010000099 DAXQKX010000000
VERSION     DAXQKX010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6602
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.102"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            374..973
                     /locus_tag="ACF3MF_002646"
     CDS             374..973
                     /locus_tag="ACF3MF_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFE3928546.1"
                     /translation="MKSVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLSDVLEISRGRVIVKERLAMKEQKTAKHNSVFISNKLRKVILDYVQSEFPEQ
                     LQVHDFSKYLFPSRKLADTPLTRQSLWRIIHEAGTAVGLKEIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            1022..1492
                     /locus_tag="ACF3MF_002647"
                     /pseudo
     CDS             1022..1492
                     /locus_tag="ACF3MF_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405176.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1706..1969
                     /locus_tag="ACF3MF_002648"
     CDS             1706..1969
                     /locus_tag="ACF3MF_002648"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928547.1"
                     /translation="MKQIQNDLYGNIEKEYFDSQMFQQNSSPYYSEERFFQLMEQEEE
                     KRLLQLMKEMEEQQVAEEIEEKRFIKLIEEQMEIESLREQEEE"
     gene            2117..4219
                     /locus_tag="ACF3MF_002649"
     CDS             2117..4219
                     /locus_tag="ACF3MF_002649"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000921212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Dam family site-specific
                     DNA-(adenine-N6)-methyltransferase"
                     /protein_id="HFE3928548.1"
                     /translation="MMTTQDLMDKYEVSRQTVNNWVRKNEIPAPTVKKGHQNAWTFSQ
                     AELIDKKLKHSHSEQLELFKTESTPLHINNRRYLGSKQKILDFINDVVSEHTKNVKSV
                     ADVFGGTGVVANLFNKQGKKVIVNDILTSNYISYETWFGNMPVDEKKIQFKIEELNSL
                     EGIHGYVDKNFGNKYFSVENAQKIDAVREKIETYNDLNEREKAFLLTSLLYAMDKVAN
                     TVGHFDAYRKKMDTFKPIYLRVPEFNKNVGNEIYNEDANQLVRKIKTDLVYIDTPYNS
                     RGYESAYHVLENVMEWKKPDVEGVAMKAVNRSEKSSDYTKSKAPQAFDDLIQNINARY
                     ILVSYNNMAKKGNSRSNAKISNEEIIATLKKRGQVEVFSIDFNAFTTGKSNIENHKEL
                     LYLCTVDDEIIQSPLNYTGGKQKLIPQLRPYFPSRYTRLIDLFSGGGSVTANLAKNGQ
                     AESYLMNDVENHVINFFEYISTIDIDDFINQAEMKISEYGLSNTKKNGYEFYSANSAS
                     GLGAYNKEKFLKLRKDYNNSPSPLLFYLLVVFGFNNQIRFNSKGEYNLPVGKRDFNKK
                     MEEKLRKFVKVIQDSPIEYSTKDFREVSIDTGDFIYADPPYLITTAAYNENGGWSEKD
                     EKDLYDYLDKANENNIKFALSNVIIHNGRENEILKSWASKYNLYVLNYNYNNSNYQSK
                     AKQSETVEVLVTNYERDI"
     gene            4219..6174
                     /locus_tag="ACF3MF_002650"
     CDS             4219..6174
                     /locus_tag="ACF3MF_002650"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: protein motif:HMM:NF021040.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlwI family type II restriction endonuclease"
                     /protein_id="HFE3928549.1"
                     /translation="MKLTNTAETFNLGDTSFRRKTLIDDYKTLLPYLQETNLEFNEWN
                     NVAQAEFYEKILTKTDLFSRNTDEDFAKRGRTLTNALVKIGLTNSKRKLSRVANSWIN
                     ENTLSANDVERSLGIDANNLLFTRQLLKLRVYDSNKMNYFYPFRVALGLVIKYQNIPQ
                     QDFLTLIHLIQPSFDNRKIKDIINDYHSVNDNNEIFSEFLDRNFPENTSELTADELFS
                     KKPLNRKEFDSLFVNRKSSATQGIYFEFVNKLLAFKSNKNVENLDALLELNSNDKLTK
                     AFGFGKAIFAKTNFMKSKNIQDFLDENVDNDLLSENNTLIYNQFVLSKKDDIVREYRD
                     MTKRTFNLSGLLDFNTGLVNATNQDVLSIIFSSMSFSGTENYADYEENLSYSFYQEST
                     ITEVLDLDESAILSEIKAFLGIENTSQIESVVLTQKEDKFRKFISKTFPREKIIEILP
                     LFSPRDDKKIKSEVSESATVPTIYEYIVAIAWFYISKEEFFITKSLNLTLDGEMRPLS
                     HAAGGAGDIVIDYENLTLMLEVTLMNAQAQKRGEWEPVLRHATNLTVDNFDKNVITLF
                     IADELDDNTVNIWRAVASVPLRSSNKDEIADLVKIFPLENRELLHMLKNNLDERKLLK
                     AIDESYEELAGNFDLSWRDKIFVEANM"
BASE COUNT         2398 a          955 c         1234 g         2015 t
ORIGIN      
        1 gattcatcgt cattcctcct gctatctttt tctattattc taccttattt gatagtagat
       61 ttaaaacttt gcaacagaac cgttaattat atagactgaa aattttgaat tttcagaata
      121 gaacaactta aaagtactga caaaattttt taaaggggca atattaatgt tctgagataa
      181 tcaaatctta ccgaaaatct caaaagtcca atgtgacaca agctgattct gtcacattcg
      241 ttaaaatcgc tccatcctta gaggctctaa gaggaaatca cttttctttt agggcctttt
      301 ttctatagct tgtttaaatg tgacttatta tctgttataa tcatattaag taacatttga
      361 gaggggacta aaaatgaaga gcgtggaacc gattcgcgac aaaaaaaaga tcgatgccat
      421 gaaggccatt ttggcttccg gaaaatatgg gcaacgaaat ttggtgcttt tttcaatcgg
      481 gatcaataca gcctatcgaa tctccgattt aaggcagttg aaattaagtg atgtgttaga
      541 aatttcccgt gggcgggtga ttgtcaaaga acgtctggcc atgaaggaac aaaaaacggc
      601 caaacataat tcggtcttca tttcaaacaa attacgaaaa gtgattctcg attatgtcca
      661 atccgaattt cctgagcagc tgcaagtaca tgacttcagc aaatatttgt ttccaagtcg
      721 aaaattagca gatacgcctt tgacccgaca aagcctttgg cggatcattc atgaagcagg
      781 aacagcggtt ggtttaaaag aaattggtcc ccattcgatg cgcaagacct tcggctattt
      841 tttgtacaag caagggacca aaacagagat cattcagtcg ctgctcaacc attcttcgca
      901 acgggagacc ttacgctata ttgggatcac ccaggaagat aaagataccg cagtaaagag
      961 tttggatctg tgacagaata atgccctata taatagaaga aaaaattcaa gaggggagaa
     1021 gatgaacgaa gaaaagcgtc cgaaatttcc tgataaatac cacttatctc gcaaagagtc
     1081 tgtgtattta ttgaagaaaa acattgtgga actggtgtat aatgcgggaa aatttgaagg
     1141 gttaaataca acgctattac aaacagaaga gattatcaag tataatcgag ctaataatat
     1201 ggcggtagat gatgtcctga ccgtcgttaa cttaaaaaga ggctttgaaa tgcttttaaa
     1261 cgacttacag gagcccctaa tagagacaag taagcggatt aatcggatcg ttgcagcaga
     1321 ggatgcgctt ttttccggtg aaatacgaac tggtggggta gaagtatcga cgattcaagg
     1381 aagatatgtg ccaccaatgt taactgaaga cgaggtaaac aatcaatatg gtgagataat
     1441 gaataaagag atatcagata cggaaaaagc cctgcgactg tttctattca tttaatgcaa
     1501 taggagcggg tatttgtaat gcttcccata gtgccacccc atttttgaaa tcaatttccc
     1561 acgtttcttc gttctcgcca ttctttggga gaagctcaag agatggcgga gtaaaatcaa
     1621 attcgctttt cattatatta attgtctaac ttaatttgac aattaatatt atttatacag
     1681 cacaagtgag aaatatattg aacagttgaa acaaatacaa aacgatttgt acggtaacat
     1741 tgagaaagaa tattttgata gtcaaatgtt ccaacaaaat tctagcccct attattctga
     1801 agaacgtttt tttcaattaa tggaacagga ggaagaaaaa agactacttc aattaatgaa
     1861 agaaatggaa gaacaacaag tagcggaaga aatagaagag aaacggttta ttaaattaat
     1921 agaagagcaa atggaaatag aaagtttaag agaacaagaa gaagagtaag ttctgcgttt
     1981 gttagaaaca taatatcttt gaaaacaatt tagacaaacg acaggaaatg gtaatttgaa
     2041 aactaaacat tgataattac ttattgcact taatatggta gaattgcatt aactgtaaag
     2101 agagggtgat gcctaaatga tgacaacaca agatttaatg gacaagtacg aagtatcacg
     2161 acaaactgta aacaattggg ttcggaaaaa cgaaattcct gcacccacag taaaaaaagg
     2221 gcatcagaat gcttggacat ttagtcaagc ggaacttatt gacaaaaaat tgaagcatag
     2281 tcacagcgaa caattggagt tgtttaaaac tgaatcgact cctcttcata tcaataatag
     2341 aagatattta ggcagtaaac agaaaatact agattttatc aatgatgttg tttcggaaca
     2401 caccaaaaat gttaagtcag ttgctgatgt ttttggtgga acaggtgttg ttgctaattt
     2461 atttaacaag caaggcaaaa aagtcatagt taacgatatt cttacaagca actacatttc
     2521 ttatgaaaca tggttcggga atatgcccgt agatgaaaaa aagattcagt tcaaaattga
     2581 agaactgaat tctcttgaag gtatacatgg atatgttgat aaaaattttg gtaataaata
     2641 tttttcagtt gaaaacgcac aaaaaattga tgcagtccgt gaaaagatcg agacttacaa
     2701 cgatttaaac gaacgtgaga aagcattttt gttaacgtct ttgctatatg ctatggataa
     2761 ggtggctaac acagtaggac attttgatgc atatcggaaa aaaatggata cctttaaacc
     2821 tatttattta cgagttcccg aattcaataa aaatgttgga aatgaaattt acaatgaaga
     2881 tgctaatcag ctagttagaa aaattaaaac agaccttgtt tacattgata caccttataa
     2941 ttctcggggc tatgaaagtg cttatcatgt tttagaaaac gttatggaat ggaaaaagcc
     3001 ggacgttgag ggagtggcaa tgaaagcggt caaccgctct gaaaaatctt cggactatac
     3061 taaatctaaa gcaccccaag catttgatga tttgattcaa aatattaacg ctcgatatat
     3121 tttagtttcg tacaataata tggcgaaaaa aggaaattca cgttcaaacg caaagatttc
     3181 aaatgaagaa attattgcca cattgaagaa acgtgggcag gtagaagttt tttcaattga
     3241 ttttaatgct tttacaacgg gcaagtcgaa tatagaaaat cataaagaat tactgtatct
     3301 ttgcacagtt gatgatgaaa taattcaatc gccactgaat tatacgggcg ggaaacaaaa
     3361 attgattcca caattacgac catattttcc ttcaaggtat acacgattga ttgacttatt
     3421 ttctggtggt ggtagcgtta ctgcaaatct ggcaaaaaat ggacaagcag aaagttatct
     3481 tatgaatgat gttgaaaatc atgtgattaa tttttttgag tatatttcaa ctattgatat
     3541 agatgatttc attaaccaag cggaaatgaa aataagtgaa tatgggttat ctaatacgaa
     3601 aaaaaatgga tatgaattct attctgcgaa tagtgctagt ggtttaggtg catacaataa
     3661 agaaaaattt ctgaagctaa ggaaagatta taataattca ccgtcaccat tgctatttta
     3721 cttgttagtt gttttcggtt ttaataatca gattcgcttt aattcaaagg gtgaatataa
     3781 tcttccagtt ggtaaacgag actttaacaa aaagatggag gaaaaattac gtaagtttgt
     3841 aaaagtaata caggactcac caattgaata ttccaccaaa gatttccgag aagtgagtat
     3901 agacacagga gatttcatct atgctgatcc gccgtatctt attacgacgg cagcttacaa
     3961 tgaaaatggt ggttggtctg aaaaagatga aaaagactta tacgattatc tagataaagc
     4021 aaatgaaaat aatattaagt ttgctctttc aaatgtgata attcataacg gaagagaaaa
     4081 tgaaatcctt aaaagttggg cttcaaaata taatttgtac gtcttaaact ataattacaa
     4141 taatagcaac tatcagtcca aggctaaaca aagtgaaaca gttgaagttt tagtcacaaa
     4201 ttacgagagg gatatttaat gaagcttaca aataccgcag aaacatttaa tctaggtgac
     4261 acaagtttta gaagaaaaac attaattgac gactataaaa ctttgttgcc ttatcttcaa
     4321 gaaacaaatc tagaattcaa tgaatggaat aatgtcgcgc aagcagaatt ttacgaaaaa
     4381 attttgacaa aaacagattt attttctagg aatactgatg aggattttgc aaaacgtggg
     4441 agaaccttaa ccaatgcctt agttaaaatt gggctaacaa attcaaaaag gaaactttca
     4501 agagttgcta atagttggat aaatgaaaat acgcttagtg caaatgatgt tgaacgttca
     4561 ctaggaattg atgcgaataa tttattattc actcgtcagc tgttaaaact acgtgtttat
     4621 gattcaaata agatgaatta tttttatcca tttcgtgtcg cattgggatt ggtgataaag
     4681 tatcaaaata tcccacaaca agattttcta acactaattc atttaattca gccgtcattt
     4741 gataatagga aaataaaaga catcattaac gactatcaca gtgttaatga taacaatgaa
     4801 attttttcgg aatttttgga tagaaatttt ccagagaata caagtgaatt gactgctgat
     4861 gaactttttt caaaaaaacc attaaataga aaagaatttg attcgctgtt cgtgaataga
     4921 aaatcttcag ctacgcaagg aatatatttt gaatttgtaa ataagttgtt ggcgtttaaa
     4981 tctaacaaaa atgttgaaaa tttagatgct ttgcttgaat tgaattctaa cgataaatta
     5041 acaaaggcat ttggatttgg aaaagctatt tttgctaaaa cgaattttat gaaatctaaa
     5101 aatatccaag attttttaga tgaaaacgta gataatgatt tgctgtcaga aaataatacg
     5161 ttgatttaca atcaatttgt actttctaaa aaagatgata tcgttcgtga gtatcgagat
     5221 atgacaaaac gaacattcaa tttatcggga ttattagact tcaatactgg actagtcaat
     5281 gctaccaatc aagatgttct ttcgataata tttagttcta tgagtttctc gggaactgaa
     5341 aactatgctg attatgaaga aaacttgagt tactcattct atcaagaatc tacaataact
     5401 gaggtattgg atttagatga atctgctatt ttgtcggaaa ttaaagcatt tcttggaatt
     5461 gaaaatactt cacaaatcga aagtgttgtt ttaacgcaaa aagaagataa atttagaaaa
     5521 tttatctcaa aaacatttcc tcgagaaaaa attattgaaa tcttaccgct attttcaccg
     5581 agagatgata aaaaaattaa atcagaagta tcagaatcgg caacggttcc aacaatttat
     5641 gaatatattg ttgctattgc atggttttat atttctaaag aagaattttt tattacaaag
     5701 agtttgaatt taaccttaga cggtgaaatg cgtccgttat cacatgcagc tggtggtgct
     5761 ggtgatattg tcattgatta tgaaaacttg acattaatgc ttgaagttac tttgatgaat
     5821 gcccaagctc aaaaacgtgg agaatgggag ccagtattac gacatgcaac aaatttgacg
     5881 gtagacaact ttgataagaa tgtcattact ttatttattg ctgatgaact ggacgataat
     5941 actgtaaata tttggcgagc agttgcaagt gtacctctac ggtcatcaaa taaagatgaa
     6001 attgcagatt tagtaaagat tttccctctg gagaatcgag aactacttca tatgctgaaa
     6061 aacaatctcg atgaacgaaa actattaaaa gcaattgatg aatcatacga agaacttgcg
     6121 ggcaattttg acttaagttg gcgagataaa atttttgttg aagctaatat gtaaaaatgt
     6181 agtagtttcg atttaaacgg gaatgttttt tagtcaatgg aaaatatcac ttaatggtgt
     6241 gaacttatgg taaaagctag ctcaattcgt tttatttagg gttaaaattc acaccattca
     6301 aatgatatta gttgaaatta gatgaagttt tgttatttgc aatcgcccaa aagatttgat
     6361 aataaaagct tttgaaagtt attcaattag gcgttgttca agccaggtct taaaggcgct
     6421 cgtcgttcac tacagttctc aacgttaata tcgttgctat ttcaacgttt acagcactct
     6481 ttggattatt tcaaagagtg tttttttgta tttttataga ggtatttaga taagtttgtg
     6541 gaggtttgtt gcgctttatt ttgctatcca ggagttcatt attttaaaag cttaaataat
     6601 aa
//
LOCUS       DAXQKX010000100         6432 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.103, whole genome shotgun sequence.
ACCESSION   DAXQKX010000100 DAXQKX010000000
VERSION     DAXQKX010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6432
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.103"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(99..1229)
                     /locus_tag="ACF3MF_002651"
     CDS             complement(99..1229)
                     /locus_tag="ACF3MF_002651"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HFE3928550.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="ACF3MF_002652"
     CDS             complement(1878..3080)
                     /locus_tag="ACF3MF_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFE3928551.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="ACF3MF_002653"
     CDS             complement(3140..3343)
                     /locus_tag="ACF3MF_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HFE3928552.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4552)
                     /locus_tag="ACF3MF_002654"
     CDS             complement(3485..4552)
                     /locus_tag="ACF3MF_002654"
                     /inference="COORDINATES: protein motif:HMM:NF014537.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFE3928553.1"
                     /translation="MLDSLQEEVVPVNRVLIDYLTIHFFSNQHLKLIEEIIEMPIERF
                     EELDYAPKGYIGQYVWNQVITIRYSIDDAVKGTVMEFSGQGCKHLARWLKTRKTNWQQ
                     FFRKVLDYQGNFTRIDFTLDDFVGSLSIPELKHKVILGHVWTTFQVSESHGGTDIINN
                     ESNGETLYLGSKKSQCRFCFYQKDHEQRKRRGIPLEEAKVKNRFELRYRKEKAQSLAK
                     IISKTHDLTKLFFELLNGAICFYDRDPNDLGAKVDAKWAAFISNYGAITISLDTIPQS
                     FEKTMSWLIHGVSPSLVFIAQVDQTFHSSLLPLIIEQGEMNPRQIKLLQNMKADPEYY
                     QEEVEYYERKLQSISNEKTSY"
     gene            complement(4610..4717)
                     /locus_tag="ACF3MF_002655"
     CDS             complement(4610..4717)
                     /locus_tag="ACF3MF_002655"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3928554.1"
                     /translation="MNQVNQHDLGEAIRVSREERGWTQRYLAEKVGISR"
     gene            4880..5692
                     /locus_tag="ACF3MF_002656"
     CDS             4880..5692
                     /locus_tag="ACF3MF_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3928555.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6066..6257)
                     /locus_tag="ACF3MF_002657"
     CDS             complement(6066..6257)
                     /locus_tag="ACF3MF_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928556.1"
                     /translation="MKQKFFIAIIATKKFHRGKRFGQKWKFPPKVTAPQLKSIKELEF
                     ENALVICMTCTDEVFRKHF"
BASE COUNT         1930 a         1313 c         1008 g         2181 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcataga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatattttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatacaac agtgatgatt
     6361 cctaataaag aaaagactac aataatattt ttctaactta tcgccttcaa agaaatagtt
     6421 tcttattttt ca
//
LOCUS       DAXQKX010000101         6303 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.104, whole genome shotgun sequence.
ACCESSION   DAXQKX010000101 DAXQKX010000000
VERSION     DAXQKX010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6303
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.104"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            334..714
                     /locus_tag="ACF3MF_002658"
     CDS             334..714
                     /locus_tag="ACF3MF_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HFE3928557.1"
                     /translation="MSEQHQNLASDHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVAPD
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            696..1610
                     /locus_tag="ACF3MF_002659"
     CDS             696..1610
                     /locus_tag="ACF3MF_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HFE3928558.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     TLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPNHQIAIYTHTDKDHIHN
                     HIVINSVNLETGKKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKTEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYTQFCDSLKTFGIHCLNRGKNFTYELVHKKK
                     KVRSNKLGKDYEKETILHELDRRERTYNQQRTNELRRARASIRETAEEVRREQRTFTP
                     EQSEIRPTRRNHEQHVERGTDHQQELSL"
     gene            1855..2544
                     /locus_tag="ACF3MF_002660"
     CDS             1855..2544
                     /locus_tag="ACF3MF_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928559.1"
                     /translation="MAFYLPYLLISASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLV
                     GVIFALSIVLSGLFGVLEGNKRVSRSILLGDITQKYEAACDKKKKEQALAQKMEEFTA
                     CYEDMNNIFVDQEKRLTDKNMKKLTRFYQNLPEKQQKEVQEKYEQVKKDVQYFKDTQT
                     EEACCNLFSDTIPFSTSEQERKERQQSVTYERYETLLQQATNIQNPTKKETALNYLES
                     VKEWLDQQQQN"
     gene            complement(2665..2751)
                     /locus_tag="ACF3MF_002661"
     CDS             complement(2665..2751)
                     /locus_tag="ACF3MF_002661"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HFE3928560.1"
                     /translation="MFERFICPLLVEVCVSLFSYWLNNRNKK"
     gene            3427..4377
                     /locus_tag="ACF3MF_002662"
     CDS             3427..4377
                     /locus_tag="ACF3MF_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HFE3928561.1"
                     /translation="MANEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMREKGDKTVR
                     LTFDQLKDLSNYKATANNRFINDLEMTYDKLMDLRFGKRSANGLDIDRFVMFSEFKIR
                     GTAKDPYVDIQVYEKALPLLNNLDEWVRYSLQQFNELQSSYAKTMFRLLKQYRTKGFA
                     YFSKEDFHELLDIPKSYWNNQANVDNRVIKPIRQELTAIFKGLSIKKKYGKGRGKPVV
                     GYQFTFKPEIKKADDFNKHAPTKEEQNKALALADKQKEYEEPATTINEKIKQKKRELE
                     LLQQIKQLEKEKEALEKQTESALSKKEKKSLLSDLDNLFQ"
     gene            4398..4931
                     /locus_tag="ACF3MF_002663"
     CDS             4398..4931
                     /locus_tag="ACF3MF_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFE3928562.1"
                     /translation="MQPQETFTIKELSELFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLGNQMLLDRLHEYEQDNDKNVNIPSKNVVTNKLLDQLREENEFLRE
                     QLALREQNNSHIQKLLDQQQQLTLQANKQIEKLQEKLQLTYTEEAPENDSTTLSEATE
                     TIDKQIDTEKKWWQLWK"
     gene            4947..5117
                     /locus_tag="ACF3MF_002664"
     CDS             4947..5117
                     /locus_tag="ACF3MF_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928563.1"
                     /translation="MTRKNLLFGSILLGILGFSPMLLSVINKGNKHGELKLNPNYYNS
                     PNEELFVKETDK"
     gene            5567..6100
                     /locus_tag="ACF3MF_002665"
     CDS             5567..6100
                     /locus_tag="ACF3MF_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928564.1"
                     /translation="MKKFTLGVALLTIGAVVLPSTTIVYASENSQVVSLNENNATENV
                     VIEYTEDGMVVTKYEDGYSAEDFANSSDIMTRAAVARWGKKEYTNIAVTTGVAANAIN
                     AAFWAGGKASTSMFGIPGWAIGALLTGASWTKKGASPGNAVAKEWDKNGNGWIGFYYQ
                     RGYDAAGRVVATRYSTL"
     gene            6112..>6303
                     /locus_tag="ACF3MF_002666"
     CDS             6112..>6303
                     /locus_tag="ACF3MF_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928565.1"
                     /translation="MFLISKSLKSLKTFTKKNPQIATIRIFIFAIAVAIIVNMLSGGQ
                     LYKSGLFLVLILVVLDIIKS"
BASE COUNT         2324 a         1100 c         1175 g         1704 t
ORIGIN      
        1 aaaaaaaaat aaatcgatac attttagaag aatagggttg tttgaatatt acaaagcaac
       61 aatttcacct tcggtgaaat aagcgaaact ttacaaaaag tggctagcaa atgctagcct
      121 ttttttgtat tgtggagcgt ggattttgag ggggattcaa gggggagctt gcgctccttt
      181 gacaagcggt tatttgcacc aaatacggag gtatttggct agcaaatata gagcttgcca
      241 aaccctttta gtgagcttta ctcattgtac ctttttaggt acaatggtat tgcgaacgat
      301 acgtccgtag gacgtactga aagggtggga cttatgagcg aacaacatca aaatttggct
      361 agcgatcatt ctaaaaaata tacctatcga tccgagccaa aacaaatcag ttttcgagtg
      421 agcgaatccg aatttgcaaa gctgaagcag tcagctgaag ctttgcaaat gagtgtgccg
      481 gctttcgtga aagccaaggc acaaaacgcg cgtctggtga caccgaaagt ggcgccagac
      541 attgcccagg caatcgcgcg cgatttagcc aaagctggag ggaatatcaa tcaaattgcc
      601 aagtggtgca atacacacca acacgacgtt gctcctgatg atgctcaacg tttatccgaa
      661 aacctaaaaa tcatgcaaaa ggagctacaa aagatatggc aacagttaaa gtaagtcgaa
      721 ccacttcatg tagccgagca atcaattacg cagaaccacg agcaaccgtc aaaacaggaa
      781 taaactgtga cattgattat gccaaaagtg aaatgaaaca aatacgcacg ctttatggaa
      841 aagacgatcg tgtacaagca cacttattga ttcagtcctt tcgaccagga gaaattaccg
      901 ctgaaaaagc caatcaacta ggggcagagt atgcgaaaaa aatagcccct aaccaccaaa
      961 tcgcgattta cacacataca gacaaagacc atattcataa tcacattgtc attaactccg
     1021 ttaatcttga aactgggaaa aaatttcaag cccatgggca agcattttta aacaaatgtt
     1081 atgacctaaa tgacgagatt tgtcttgaac atgacttaac aatcacggaa cgaggaaaga
     1141 aaaccgaaaa acgaaccatg tctgaaatta aattaaaaga aaaaaatgaa ccggtttgga
     1201 aagacgaaat tcggtttgcg attgatcaaa caatgaaaaa caaaaaaact cgaacgtata
     1261 cccaattttg tgattcactt aaaacattcg gcattcattg cttgaatcgc ggaaaaaatt
     1321 ttacttacga attggtccac aaaaagaaaa aagtacgatc caacaaacta ggaaaggatt
     1381 acgaaaagga gacgatttta catgagctgg acagacgaga acgaacctac aatcaacaac
     1441 gaaccaacga gctacgaaga gctcgagcta gcattcgcga aactgcagaa gaagtacgaa
     1501 gagaacaacg aacttttacg cctgaacaat cggaaattag accgactcga agaaaccatg
     1561 aacaacacgt tgaacgagga acagaccacc aacaagaatt atcgctctaa aacgttaaaa
     1621 gacatcgaaa acgaaataaa gagacaacgt gcctttcttg cgccttatac ccaagaaagg
     1681 atacaaacta cgatggattc acaagtcaaa aaactccacc aagcgctatt agaccagcga
     1741 aaccaagaac aaaaaaaggc tttaattcaa cgatcgatgg atattcttgc ccccttatgt
     1801 tgcttagtac taacattatt agccttttgg ttggtatggg gagaataaac agacatggca
     1861 ttctatttac cctatctact catttctgcc agtattttag gaattatttg gcttagctat
     1921 aaggcttatc aaacaagata ttcattaaaa ggctctaaaa ttcgatttaa gcgattttta
     1981 ttggtcgggg ttatatttgc cttatcaatc gttttaagtg gtttattcgg cgttttagag
     2041 ggtaataaac gtgtttcaag aagcatttta ttaggggata tcactcaaaa gtatgaagca
     2101 gcatgtgata aaaagaaaaa agagcaagca ttagcacaaa aaatggagga atttaccgct
     2161 tgttatgagg acatgaacaa tatttttgtg gatcaagaga aacgtttaac agataaaaac
     2221 atgaaaaaac tcactcgttt ttatcaaaac ttaccagaaa aacagcaaaa agaggtacaa
     2281 gaaaaatatg agcaagtaaa aaaagacgtg caatatttta aagatacgca gacagaagaa
     2341 gcttgttgta acttatttag cgatacaatc cctttttcaa ccagtgaaca agaacgaaaa
     2401 gaacggcaac aatcggtcac atacgaacgt tatgaaacac tgcttcagca agcaacaaac
     2461 atacaaaatc caacgaaaaa agaaacggca ttaaattatc tagaaagtgt caaggaatgg
     2521 ttggatcagc aacaacaaaa ttgaatttga ttagcaatca tgttaaactg aacctgcaaa
     2581 tgatcaaaca ttagatacac gaaagcccca gagaggtcgg attctctggg gctttttttc
     2641 aggttgatgt cgcctttatt gattttactt cttgtttcgg ttattcaacc aataactgaa
     2701 taaagagaca caaacttcta caagaagggg gcaaatgaac cgttcaaaca ttagatacac
     2761 ctccttccag tcgcaagact gtcggatagg cgacaagtta ttatacctta caaaataaaa
     2821 tctgtgtggt gtttttaagt atcccttatt ttcgggttgt tagggcttgc cctgaccgcc
     2881 tgtaaggcgc tttaagaaca agataaggtt ttttacccaa gactgtctta aaacgactta
     2941 gacgagctat cagaggcttc ccccacctcc gttactgact tgtttttagc aaaggagcct
     3001 ttaggcgact gcgcagtaca atgtgagagc atagcgatca cactttttta gcgaccgtag
     3061 ggagcaaggt tttgaattgg cagttttgaa aaatgcgcga acctgttggt agaaaaaaga
     3121 agtggttttt aggcgggaaa ttttgtcacc ctcttttata atctcttttt aaaccttttt
     3181 ttaaacctct ttaccgtcgg ctgtgtcctt actccttcaa tggatacagc gttttataaa
     3241 ctacattttg tctgctttta aactacattt tgtctgcttt taaactacat tttgtctgct
     3301 tttaaactac attttgtctg cttttaaact ctttttttgc actcacgtat gttataatat
     3361 gcattatcac agacaaaacg ttgtttataa cgtctgtatc cattgaagga gtaaggagga
     3421 atatctttgg caaatgaaat cgtgaaatac catcatgaat taaataccat tccgttgcgg
     3481 aaatttacac cagttgaaat gaatctattt ttctctattg tgtctagaat gcgcgaaaaa
     3541 ggcgataaaa cagtccgtct tacttttgac caactaaaag atttaagtaa ttataaagca
     3601 actgctaata atcgtttcat taatgattta gaaatgactt atgataaatt aatggattta
     3661 cgttttggta aaagaagtgc taatgggctc gatatagata gattcgttat gtttagtgag
     3721 tttaaaatac gtggaactgc taaagatcca tatgtagaca tacaagttta cgaaaaagct
     3781 ttacctttac taaacaattt agatgagtgg gttcgctatt cactccaaca atttaacgaa
     3841 ttacaaagta gctatgcaaa gactatgttt cgattactaa aacaatatcg aactaaaggt
     3901 tttgcttatt tttctaaaga ggattttcat gaactattag atattccaaa aagttactgg
     3961 aacaaccaag caaacgttga taatcgtgtt ataaagccta tacgacagga attaaccgca
     4021 atcttcaaag gattatcaat caaaaagaaa tacggaaaag ggcgaggaaa acctgtcgtt
     4081 ggctatcaat ttacgtttaa accagaaatc aaaaaagcag atgattttaa taaacatgca
     4141 ccaaccaaag aagaacaaaa taaagcattg gctttagctg ataaacaaaa agaatacgaa
     4201 gaacctgcta caacaattaa cgaaaaaatc aaacagaaga aacgagaact tgaactcctc
     4261 caacaaatca aacaactaga aaaagagaaa gaagctcttg aaaaacaaac agagtccgca
     4321 ctttcgaaaa aagagaaaaa aagtttatta tctgatttag ataatttatt ccagtagcaa
     4381 cctaggaggc aaccagtatg caaccacaag aaacctttac aataaaggaa ttgtcagaac
     4441 tttttaagat gagtaggcaa gcaatatcga aacatatcca aaaattagat tcttccatga
     4501 tagctaaaaa tgagcgtggt tataaggttg tattgcgttc tggagtattg caacttgctc
     4561 gcaacttagg caaccaaatg ttgctagata ggttgcacga gtacgaacaa gacaacgata
     4621 aaaatgttaa tataccaagc aaaaacgtgg ttacaaacaa gttgctagat cagttgcgtg
     4681 aagaaaatga atttttacga gaacaacttg ccctcagaga gcaaaataat tctcatatac
     4741 aaaaactact cgaccagcaa caacaactca ccctacaagc caacaaacaa atcgaaaaac
     4801 tgcaagaaaa actacagttg acttatacag aagaagctcc agagaatgac tcaacgactc
     4861 tttctgaagc aacagaaaca atagacaaac aaattgatac tgaaaaaaaa tggtggcaac
     4921 tttggaaata actggaggga acattcatga caagaaaaaa tcttctattc ggttctattt
     4981 tactaggaat tctaggattc agtccgatgt tattgtcagt gatcaataaa gggaataaac
     5041 atggtgaatt gaaattgaat ccaaattatt acaacagtcc taacgaagaa ttgtttgtaa
     5101 aagaaacaga taaataataa aaaagactgc tctttcgagc agccagttaa aaaataatga
     5161 gtgtttattc ttgaaaaagc aacgcgctta tgaagcgcta ccaaaaattt atcatatttt
     5221 attaaaaata acaacccagt aaaaaatgac tggtaaaaat tcacaaagaa acggaaagaa
     5281 gcaaccgcag aaaatcaagc ttaaaaagag cttttgacct agaccaatcg aaaatcacaa
     5341 agtgagcctc tgtatcggtt gatacaaggg ctacttggca tagtgtacat tatgtcaaca
     5401 agaatttaat ataacatatt ttcctaatgc attctaacta taccacatta tcaaaaatat
     5461 aaattatctt tactaaataa aatattgaca agcctatacc ttttgtttta tgattttcac
     5521 aaagaaaacg ttttctatat atttttctgt atcaggagga aattctatga aaaaatttac
     5581 tttaggggta gctttgttaa ctattggggc agttgtttta ccgtcaacta ctatagttta
     5641 tgcttcagaa aattcccaag tggtatcatt aaacgaaaac aatgctactg aaaatgtagt
     5701 tattgagtac actgaagatg gtatggtcgt aactaaatat gaggatggtt atagtgcgga
     5761 agattttgca aattcttcag atatcatgac aagagctgca gttgcaagat ggggcaaaaa
     5821 ggaatataca aatattgctg taaccactgg agtagctgct aatgctatta atgctgcctt
     5881 ttgggcagga gggaaagcta gcacttctat gtttggtatc ccaggttggg caattggtgc
     5941 tttgttaaca ggtgcaagtt ggactaaaaa aggtgcttct ccagggaatg cagttgcaaa
     6001 agaatgggac aaaaatggta atggctggat tggattttat taccaaaggg gatatgatgc
     6061 agctggaaga gttgtagcta ctagatattc aacgttataa gttaaggagt gatgtttttg
     6121 atatctaaat cattaaaatc attaaaaaca tttactaaaa agaatccgca aatagctact
     6181 attcgtattt ttatatttgc tatagctgtt gctataattg ttaatatgct aagcggaggg
     6241 caattataca aatctggttt atttttagtg ttaatcttag ttgtcttaga cataataaag
     6301 tct
//
LOCUS       DAXQKX010000102         6274 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.105, whole genome shotgun sequence.
ACCESSION   DAXQKX010000102 DAXQKX010000000
VERSION     DAXQKX010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6274)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6274)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6274
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.105"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..1758
                     /locus_tag="ACF3MF_002667"
     CDS             <1..1758
                     /locus_tag="ACF3MF_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0031419 - cobalamin binding [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12-dependent ribonucleotide reductase"
                     /protein_id="HFE3928566.1"
                     /translation="QQNHLVEQGGSRRGAQMIMLNDWHPDIFEFIISKIQNPAILQNL
                     IHTSQSPTVRQLASEKLTFEPLTANEKEWLEFLVDHPTNDMEDKFLKTAQQKLKAGGT
                     YSVKDPDFLTGANISVCLTKEFMEAVETDQTYELRFPAIEDYDASEMADYDQHWMEVG
                     DVREWAETGRKVKIHQTIKARELWDLITYCATYSAEPGIFFIDNANEMTNAQAYGQKV
                     VATNPCGEQPLTPYAVCNLAAINLANMVDKKTKVVDFEKLTDVVRASVRFQDNVIDAT
                     PYFFKKNEQQAKGERRVGLGVMGLADLLIYCEKVYGSEDGNRLVDQVFEKIAVTAYQT
                     SVELAKEKGSFPFLVGKTAEETTALRQRFIESGYMKKMPESIRQAILKYGIRNSHLLT
                     VAPTGSTGTMAGVSTGLEPYFSFSYFRSGRLGKFIEVNAEIVSEYLEKNPEKTADNLP
                     PFFVSAMELSPKAHVSVQCTIQRWVDSSISKTVNAPKGYQVKQVAAIYEDLYQGGAKG
                     GTVYVDGSRDSQVLTLEADDNVFEEPVVGVADNQVTLDSLESSEAEEICPICHEGRIE
                     EIGGCSTCTNCKVQLKCGL"
     gene            1772..2341
                     /locus_tag="ACF3MF_002668"
     CDS             1772..2341
                     /locus_tag="ACF3MF_002668"
                     /EC_number="2.5.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008817 - corrinoid adenosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009236 - cobalamin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cob(I)yrinic acid a,c-diamide
                     adenosyltransferase"
                     /protein_id="HFE3928567.1"
                     /translation="MKIYTKSGDKGNTSTSIIGGERIKKSDARVCAYGSVDEVNSWVG
                     KIISELDDKKFELLKKELVVLQILLFDIGTDLATPIGIKEMIVGKEEVTKIETLIDFY
                     QAKVPVIEKFILPGGHPVACDMQITRTVIRRAEREITRLIVSDEPINLHAYKIMNRLS
                     DLFFVLARYVNHVYATKEPFYERAGKVFH"
     gene            2357..2761
                     /locus_tag="ACF3MF_002669"
     CDS             2357..2761
                     /locus_tag="ACF3MF_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HFE3928568.1"
                     /translation="MKKLATLLTVFIGLFIMTGCQSNQNDQASSKASTQATSEVAKSS
                     ALIKLTDSDKEITSKTVTYKSGESLLVILKANFEVKERDGFITSIDGHAQDESQNKYW
                     TFTINGKMGEKGAGETTLDNDDQVVFNLGVFK"
     gene            2963..3637
                     /locus_tag="ACF3MF_002670"
     CDS             2963..3637
                     /locus_tag="ACF3MF_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HFE3928569.1"
                     /translation="MSNFKGKQFEKDIIMVAVCYYLRYNLSYRDVSEILNERGINVCH
                     TTVYRWVQEYSQVIYCLWKKRNKSVGDSWRMDETYIKVKGKWHYLYRSIDSSGITLDI
                     WLRKKRDKQAAYAFFKRLIKQFGEPKVLVTDKAPSLSSAFNQLHSEGLFSKTEHRTNK
                     YLNNIIEQDHRSIKKRHKLYQSIRTASSTIKGIETIHALYKISQRDKSLFGFSVIHEM
                     NTLMSI"
     gene            3697..4173
                     /locus_tag="ACF3MF_002671"
                     /pseudo
     CDS             3697..4173
                     /locus_tag="ACF3MF_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628348.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            4173..5063
                     /locus_tag="ACF3MF_002672"
     CDS             4173..5063
                     /locus_tag="ACF3MF_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFE3928570.1"
                     /translation="MEELIRVEHATKTFRSKNWRGTVSEVRAVEDVSLTIHRGETLGL
                     VGESGSGKTTLGRSILNLETLTSGEIFFEGKELTALTAEDRKAAYQQMQIIFQDPYSS
                     LNPRMTALELVMEPLYHETKDAARAKAKEILAIVGITGDDVHKLPRSFSGGQRQRIGI
                     ARAVVNRPAFVLCDEPTSALDVSIQAQIIQLLLRLQKEFSLSYLFISHDLSVIRHISD
                     RTAVMYQGKLVELAPTDRLFDNPLHPYTKKLLAAAPIADPVLARGAMEQTEIQSTITL
                     TPLYEWIEVEPDHFVRREKR"
     gene            5060..5452
                     /locus_tag="ACF3MF_002673"
     CDS             5060..5452
                     /locus_tag="ACF3MF_002673"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004601 - peroxidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HFE3928571.1"
                     /translation="MTVETLTIHQGSDKLEMTTPTGNWVLAREKGYSPVQMLVSAVAA
                     CGGYVYASVLENSKITAEIEKIEVSYDRDDNKKAQPVSAIHIQFYAKIAEADHDKATR
                     CLKLVSPNCPVIQSLDPAIEVTETVTFI"
     gene            5638..6274
                     /locus_tag="ACF3MF_002674"
                     /pseudo
     CDS             5638..6274
                     /locus_tag="ACF3MF_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
BASE COUNT         2076 a         1103 c         1362 g         1733 t
ORIGIN      
        1 caacagaacc atttagttga acaaggcggg agtcgtcggg gagcacaaat gatcatgttg
       61 aatgattggc atccagatat ttttgaattc attatctcta agattcagaa tccggccatt
      121 ttacaaaatt tgatccacac tagccaaagt ccgacagtgc gccaattagc tagtgaaaaa
      181 ctgacttttg aaccactgac agcaaatgaa aaagaatggt tagaattttt ggttgatcat
      241 ccgacaaatg atatggagga taaattttta aaaacggctc aacagaaatt aaaagcgggt
      301 ggtacgtaca gtgtgaaaga ccctgatttc ttgaccggag ccaatatctc cgtctgttta
      361 acaaaagaat ttatggaagc tgtcgaaacc gaccaaactt atgagttacg ctttccagca
      421 atcgaagact atgacgctag tgaaatggct gattatgatc aacattggat ggaagttgga
      481 gatgtcagag aatgggctga aacagggcgt aaagtaaaaa tacatcaaac gatcaaggct
      541 cgcgaattgt gggatttgat tacttattgt gcaacgtatt cagcagaacc gggaatattt
      601 tttatcgata atgctaatga gatgaccaat gctcaagcct acggacaaaa ggtagttgca
      661 accaatccat gtggggaaca gccattgacg ccttatgcgg tatgcaatct agcagcaatt
      721 aatttagcca atatggttga taaaaaaacg aaagttgtcg actttgaaaa attaactgat
      781 gtcgtaagag ctagtgttcg ttttcaggac aatgtaattg atgcgacgcc ttactttttt
      841 aaaaaaaatg agcagcaagc taaaggtgaa cgacgtgttg gacttggggt catgggattg
      901 gcagatttat tgatttattg tgaaaaagtc tatggatctg aagatggaaa ccgtttagta
      961 gatcaagtat ttgaaaaaat tgctgttacg gcttatcaaa catctgttga actggcaaaa
     1021 gaaaaaggca gctttccatt tttagttggt aaaacagctg aggaaacaac cgcgcttcgt
     1081 caacgtttta ttgagtcggg ctatatgaag aaaatgccgg aatcgatccg acaagcgatt
     1141 ctaaaatacg gcattcgtaa ttctcattta ctaacagtcg cgccaacggg atcaacggga
     1201 actatggccg gtgtttcaac tggactagaa ccatatttct ctttttctta ttttagaagt
     1261 ggtcgtttag gaaaattcat tgaagttaac gctgaaatag tcagtgaata tttagaaaaa
     1321 aatccagaga aaactgcgga taatctacca ccattctttg tctctgccat ggagctttca
     1381 ccaaaagctc acgtgagtgt tcaatgtacg atccaacgtt gggtagatag ctctatctca
     1441 aaaacagtca atgcacctaa gggttatcaa gtgaaacaag tagctgcgat ctatgaagat
     1501 ctgtatcaag gcggtgctaa aggtggaact gtctatgtgg atggtagcag ggattcgcaa
     1561 gtgttgacac ttgaagcaga tgacaatgta tttgaagaac ctgtagtagg ggtggcagat
     1621 aatcaagtta ctcttgactc attagaatca tcagaagcag aagaaatatg tccgatttgc
     1681 catgagggta gaattgaaga aattggtggt tgcagtacct gcactaactg taaagtacaa
     1741 ctaaaatgtg gcttgtaaaa ggagctattc gatgaaaatt tatactaaaa gcggcgataa
     1801 aggaaatact agtactagta ttattggtgg agaaagaata aaaaaatctg acgctcgcgt
     1861 ttgtgcttac ggtagcgttg atgaagtaaa ttcttgggtc ggtaaaatta tttcagagtt
     1921 ggatgataaa aagtttgagc tgttgaaaaa agaactagtt gtattacaaa ttttactttt
     1981 tgatattgga acagacttgg ctacacccat cgggattaaa gaaatgattg tagggaaaga
     2041 agaagtaact aagattgaaa cgctgattga tttttatcaa gcaaaagttc cagtcattga
     2101 aaaatttatc ttacctggag gacatccggt ggcatgcgat atgcaaatta cacgaacagt
     2161 tattcgtcgg gcagaacgtg aaatcacacg attgattgtt tcagatgaac ctatcaattt
     2221 acatgcatac aaaattatga atcgcttatc agatttattt tttgtacttg cacgttatgt
     2281 aaatcatgtt tatgctacca aagagccatt ttatgaacga gcagggaagg tattccatta
     2341 agagagggtt ttaaacttga aaaaattagc aacattatta accgttttta tcggactatt
     2401 cattatgaca gggtgccaat caaatcaaaa tgatcaagcc tcttcaaaag catccactca
     2461 agcaacaagc gaggttgcta aatcaagcgc gctgataaaa ttgactgata gtgataaaga
     2521 gatcacttca aaaacagtca cttacaaatc aggagaatca ttattggtaa ttttaaaggc
     2581 taactttgaa gtaaaagaaa gggatggctt tattacttca attgatggtc atgcgcaaga
     2641 tgagagtcaa aataaatact ggacattcac tatcaatgga aaaatgggtg aaaaaggcgc
     2701 aggtgaaact acattagata atgatgatca ggtagttttc aatttgggtg tatttaaata
     2761 aaaattatcg ttctttacag caattgagcg ataattaagt aagagaaaat tattagtttt
     2821 taaaggaata tgttaatttt aaaacacgtt caaaccaatc atttcgaagg ggttgaacgt
     2881 gttttttggt tctgttgcaa agttttatct aaatacctat ttagtgtaaa atagctgaaa
     2941 ctaaaacata aggagaatta ccatgtccaa ttttaaaggt aaacaatttg aaaaggatat
     3001 tatcatggta gccgtatgct actatttaag atataactta agttatcgtg atgtttcaga
     3061 aatccttaac gaacgtggaa tcaatgtttg tcacacgacg gtttatcgat gggtacaaga
     3121 atatagtcaa gttatttatt gcttatggaa gaaaagaaat aaatctgttg gcgattcctg
     3181 gagaatggat gaaacttata ttaaggtaaa aggaaagtgg cactatttgt atcgatccat
     3241 tgattcttcg gggataacat tagatatttg gttgcgaaaa aagcgtgata aacaagcagc
     3301 ttatgctttc tttaaacgat tgatcaaaca atttggagaa cctaaagttc ttgtcactga
     3361 taaagcccct tcactaagta gtgcgtttaa tcaattgcat tctgaaggat tattttctaa
     3421 gactgaacac cgaacaaata aatacttgaa taatatcatt gaacaggatc atcgatccat
     3481 caagaaaagg cacaaattat atcagtccat aaggactgct tcctcaacaa ttaaaggaat
     3541 tgaaaccata cacgctttat ataaaattag ccaaagagac aaaagtctct ttggcttttc
     3601 agtgattcat gagatgaata cattaatgag tatctaagca taaaatcaaa aattaattgg
     3661 aaactcttta ttaatttttt aactttgcaa cagaaccctt ttccagtaca acgtatgaaa
     3721 caatatcccc acgagttatc aggagggatg cgtcagcggg tgatgatcgc catggcttta
     3781 ttggcgcaac cgaaattgct gatcgcagat gaaccgacga cggctttaga tgtgacgatc
     3841 caagcacaga ttttggcctt gatcaaaaac ctgcaaagag agaaccagct ttccgtcgtc
     3901 cttgtgaccc atgactttgg ggtcgttgca ggaatgtgcg actttattaa agtgatgtat
     3961 caaggtcgag tcgtggaaga aggcaccacg gaagagatct tttatcaacc tgcgcatcct
     4021 tatacgaaac aattattgca agcggcacat ttaggcgaca agcatgccga attaaaagtc
     4081 tttgactatc atgagacatt ggcaaatgag ttgcaagaaa cgcagttatc taagacccat
     4141 cgcgtttggt gcaatcagga ggtgacagaa taatggaaga actgattcgc gtagaacatg
     4201 cgacgaaaac ctttcgcagc aaaaactggc gcggcactgt cagtgaagtc cgagcggtcg
     4261 aagatgtcag tctaacgatc catcggggcg agacattggg gctagtaggg gaatctggga
     4321 gtgggaaaac cactttagga cgcagtattt taaatttaga gactttaaca agcggggaga
     4381 ttttctttga aggcaaagag ctaacagcat tgacggcaga agatcgcaaa gcagcgtatc
     4441 agcaaatgca gatcattttc caagatccgt attcatcatt gaatccccgc atgacggcac
     4501 ttgaactggt gatggagccg ttgtatcatg aaacgaaaga tgctgcccga gcgaaagcca
     4561 aagaaatctt agcgatcgtc gggatcacgg gtgatgatgt ccataaactg ccccgcagtt
     4621 tcagcggcgg acaacggcaa cggatcggca tcgctcgtgc ggtggtcaat cgcccggcgt
     4681 tcgtcttgtg tgatgaaccg acttcggcat tagatgtctc cattcaggct cagatcatcc
     4741 aattgctgct gcgtttgcaa aaagagtttt cattgtctta tttgttcatt tcccatgacc
     4801 tgtccgtgat tcgtcatatc agtgaccgaa cagccgtcat gtatcaaggg aaactagttg
     4861 aattggcacc caccgaccgt ttgtttgaca atccgctgca tccctacacg aagaaattat
     4921 tagcagcagc gccgatcgct gatcctgtgt tagcaagagg tgcgatggaa caaacggaga
     4981 ttcaaagcac gattactttg acaccattgt atgaatggat cgaagttgaa ccagatcatt
     5041 ttgtgaggag agaaaaacga tgacagtaga aacattgacg atccatcaag gaagcgacaa
     5101 acttgaaatg acgaccccaa ctggcaattg ggtgttagca cgggaaaaag gctattcgcc
     5161 agtccaaatg ctggtgagtg cggtcgctgc ttgcggtggc tatgtatacg catccgtctt
     5221 agagaattca aaaatcacag cagaaatcga aaagatcgaa gtcagctatg accgagacga
     5281 caacaaaaaa gcccaaccag tcagtgccat ccacattcag ttttatgcga aaatcgctga
     5341 agccgaccat gacaaagcga cccgttgcct aaaactcgtt tcaccaaatt gccccgtgat
     5401 ccaatcatta gatccagcga tcgaagtgac ggaaacggtg acgtttattt aatcgaaaaa
     5461 gactttgtgt gcctgaaatc aataggcgta caaagtcttt tggctctata atttatggga
     5521 ctgatgaatc agaattgatt cttcagcccc attttcattt taggtattaa aaaacatatc
     5581 gttctctagt atgattaaat caccacaaaa taaacaactg agaggacgat atgctatatg
     5641 aatgattcta tcaaaaaaat gctgagaata atagagaaag atttgatgat tacagaggtc
     5701 tcttacgaga cccttcagaa gaaaaagacg ttggtcgtcg atgctgttct ctcgcctact
     5761 cctcgtgctt gtagaagttg tggttctact gtggtagatg gaaacgggaa agcaattata
     5821 gtgaaaaatg ggaagaagga aacgattgtc cgttttgaac aataaaatca tatgcctttg
     5881 gttatgcgcc taaaaaagca gcgctatacc tgtaaaaact gtcgcaccca ttggactgct
     5941 caaagttatt ttgtccaatc cagacattca atcgcaaatc atgttagata taaaattgct
     6001 tctttactga ctgaaaaagt atctttatct tttattgcga aaagctgtca ggtatctttg
     6061 accaccgtta ttcgtacatt gaaagagttt aaaagctatt taccaaagca atctaagaag
     6121 attctcccca gagtattgat ggttgatgaa tttcgttcgc atgcttctat agaagataaa
     6181 atgagcttta tttgtgcaga tggcgaaaca ggaaaattaa tagatgtttt gcctacgcgt
     6241 aaattacctc gattaacaag ctatttctta ggtt
//
LOCUS       DAXQKX010000103         6135 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.106, whole genome shotgun sequence.
ACCESSION   DAXQKX010000103 DAXQKX010000000
VERSION     DAXQKX010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6135)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6135)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6135
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.106"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(207..1169)
                     /locus_tag="ACF3MF_002675"
     CDS             complement(207..1169)
                     /locus_tag="ACF3MF_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFE3928572.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1171..2610)
                     /locus_tag="ACF3MF_002676"
     CDS             complement(1171..2610)
                     /locus_tag="ACF3MF_002676"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004564 - beta-fructofuranosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HFE3928573.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2795..4741
                     /locus_tag="ACF3MF_002677"
     CDS             2795..4741
                     /locus_tag="ACF3MF_002677"
                     /EC_number="2.7.1.211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="HFE3928574.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            5005..5877
                     /gene="scrK"
                     /locus_tag="ACF3MF_002678"
     CDS             5005..5877
                     /gene="scrK"
                     /locus_tag="ACF3MF_002678"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HFE3928575.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIENRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT         1946 a         1054 c         1084 g         2051 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacagt tgtgtaaaaa tatcatttta gagcatgaaa
       61 aaaggagtgg atttctccac tccaaaaaag tctaactttt gggggtcact acaagttgac
      121 aactcctttt tgtttacaaa tcaattggat atctacaaat tgtattttct aacgaatttt
      181 atagacatta aaaaattaat ttaacgttaa atacttcctc cagaaagtat tgagattggt
      241 aaaatataat ccttatttgt cttttcgcct ttaatttttt tcagaagaat atcaacaata
      301 agacttgcaa tttcatcaat tggttgtctt attgttgtca attgtgggaa aaatttctca
      361 ataaaagagg taccatcgta tccaataatt tttaaatctt ctgggatatt aagtttaagt
      421 tgatgagcaa ttttcatagt gagaatggct gttaaatcat cagaaacaaa aataccatct
      481 ggtttgtgat ttataatagt tgactttatt tccatttcac gacggatagt agacagatta
      541 ttaggaattt tgaaaatttt tccatttgga ttttgaaaag aaaaacctag tgcacgtaat
      601 tctgtgggag aatccgtgtt atcatttcct gtaatcataa tggtattttg acaaccattt
      661 ttttgtaaag tcttagctgc aagttttccc ccttcaaagt tatctgaaga aacaatggaa
      721 acattaggag ctaaatttct atcaaaagca acaataggtg ctctcacacg ctcataatca
      781 gcaattccaa gattatggct tgatgagatt atgccatcaa cttggttggc ttcaagcatt
      841 tcaatgtatt ctctctcttt agcaggatca ttttgactat tgcaaataat cgttttatat
      901 ccatgtttaa ataactctat ttcgagatac tcaatgagtt cagagtaaaa gatattacta
      961 atattaggaa aaataagacc aataagctga ggtgactttc cttgaagtcc acgtgctaaa
     1021 ttatttggtt tataaccaag agttttcata gcttcatgaa ctttttgttt tgttttttct
     1081 gataaatatc ccttattatt aatgacgcgt gaaacggttg ttgggctaac tccagctaat
     1141 tcagcgacat cagttaattt tgctaccatt ttaatatttt aattcaaagt attttccagt
     1201 aggttcgcct gatttgattt gaataccatt ttggtgattt tcagggaata cacgactagt
     1261 aaacactttt tctcctttat taataaaaat ctcaatgatt gagttatcta caaaaatgtt
     1321 agcagttgtt tctttagtat caattgagca ttcacgaatc gtaccaaagt cagtggcata
     1381 ttgaatgcct gctttgctgc gatctaaaat aatttttcct tctttggtat ctacaatcaa
     1441 gctaagtcca tttcctttac tatcagagaa aagaagtaac tccgatttct gatttggagg
     1501 aaaagttagt tcaagctcat aagtattatt tgtttctgct tttgctgtaa attgttcaga
     1561 actagcacgt aatgatgtaa tagcttctac tggatattgg taaagtttac catcttttat
     1621 tgaaagttct tttacaagac tcattgctcc ctgataatca tacttatcag ttggataatc
     1681 gatatcaggt agtccaatcc aactgacaat cagagcacga ccatcaggag tattgaatcc
     1741 ttgagtcgca tacgcttcaa atccataatc aagattttga atttctgaag cgcccacaag
     1801 ttttactttt tctatgtcaa gcgattgaca gatcttaaaa gtattcggat agatattccc
     1861 ataatttagc tcagatttat ccaacccttg aggacaataa atgagaacag gttttttgtc
     1921 tacaaatact agatttggac actcaatcat gtattctgaa ccagtgccgc caaaatcaag
     1981 gttgccaact tcctcccatg tttccacgtt attgtcatcc gctttgtaaa gtttgataaa
     2041 gcctgatttt tctaaatttt gtgctccaac aatcgcatac aattgtcctt cataattaaa
     2101 catttgtgga tcacgaaaat gatcagttac atcagcaggt ttatgaataa gaacattctc
     2161 acctttcgta atgttgtagt ctttatccat ccatgctccg atttgaagtg tatcacgttc
     2221 ccaattttca tttcgaacgt ttcctgtata gagtaagaat agattcccct ctatttcata
     2281 tgcagaaccg gaataagcgc cgtggctatc tcgttttgtg tctggaagaa gttctgctcc
     2341 tgttacatga aaatgaacta aatcatctga ttcattgtgt acccattctt tcaacccatg
     2401 agcagctcca aatggccaat tttgataaaa aagcgtatat tttccgttaa aaaaagaaaa
     2461 accattagga tcgtttaaca atcctgtttt aggttcgata tgatagctag cacgccaagg
     2521 tgatcgtttt acattatcct taattttatc catctcatct ttagtccaat cagaataagc
     2581 acgatatcgt atttctcgag gtaagttcat attttactcc ttcaatttat ctttttacaa
     2641 ctagtatggt aaacgttttc cgttgaaaaa tcaatcattt catttaaaaa aataaactat
     2701 atgacaaacg tttgacatat ttttaagata tgctaaaata aatttgcatt tcagtgaacc
     2761 gttttcacgt aaaaataaaa aaggagtgat tcgaatgaat tacagtaaag tagcttccga
     2821 cgtaatacaa gcggtcggaa aagataacct tattgcagct gcacactgcg ctacacgtct
     2881 tcgtctcgta ctaaaagatg acacgaaagt gaatcaaaaa gctttagacg aaaatccaga
     2941 tgtgaaaagc acatttaaaa ttgatggaca atatcaagtg attatcggtg caggtgatgt
     3001 taatttcgtt tatgacgaac ttatcaaaaa aactggactt tcggaaattt caacagatga
     3061 tttaaaacaa attgctagta aagataaaaa attcaacccc attatggcat taattaaatt
     3121 attatcagat atttttgttc caattatacc tgcccttgtt gcaggtggtt tattaatggc
     3181 attacaaaac tttttaacag ctgctggact ttttggacca aaatcaattg aagaaatgta
     3241 tcctgcgatt gaaggtattt cctcaatgat ccaactgatg tccgctgcac cattcatgtt
     3301 cttaccaatt ttagtaggta tttcagctgc taaacgtttt ggagcaaacc aatttcttgg
     3361 tgctgcaatt ggtatgatca tgacaacacc agatcttggt ggctcaactg aatattggaa
     3421 tatttttggt tatcatgttt cacaaacaaa ctatgcttat caagttattc cagttttagc
     3481 agctgtttgg atattatcta tattagaaaa attctttcat aaaaaattgc catcatctat
     3541 tgactttaca ttcacgccat tattatcagt aatgattact ggatttttga ctttcacagt
     3601 tattggccct gtaatgttat tgttgtctaa tggaattaca gacattattg tttggctata
     3661 taacactact ggatttattg gaatgggtat ttttggagga acatattcac ttatagtcat
     3721 gactggttta catcaatcat ttccagctat tgaaactcaa ttactttcag cgtggacaaa
     3781 tggtatcgga catggagact ttatctttgt agttgcatct atggcaaacg ttgctcaagg
     3841 tgctgcaaca tttgccattt ggttcttaac taaaaattct aagacaaaaa gtcttgcttc
     3901 ctctgcgggt gtctcagcac ttcttggaat tacagagcct gccttgttcg gagttaactt
     3961 aaaataccgc tttccattct tttgtgcttt aattggttca ggaattgcta cagcagtagc
     4021 aggattactt aaagtagttg ctgtttcact tggttcagca ggtttcttgg gatttctttc
     4081 aattaatgca acatctattc cattttacgt attgtgtgaa ttgattagct ttgtagttgc
     4141 ttttgcaatt acttacttct acggtaaaac aaaagctgct ggtatcttta aagcagaaga
     4201 aattgctgaa caaacaccag ttaattcttc aaaagtagca acaacagatc caatatctac
     4261 tgatgttgaa tcaacacaaa caaaagtttc atcagaaaca attgttagtc ccatttctgg
     4321 taaagtgatt agtctttctt cagtaaatga tccagtcttt tcatcagaag ctatgggaaa
     4381 agggattgcc attaaaccaa atggaaacac ggtccattct ccagtagatg gtactattca
     4441 actcacgttt gaaactggac atgcttatgg tattaaatca aataatggtg ctgaagttct
     4501 aattcatatt ggtattgata ctgtatcaat gggaggaaaa ggatttacac aaaaagttac
     4561 tactaatcaa aaagttagaa aaggcgatat tcttggagca tttgaccgtt caatgattga
     4621 gaaagaaggt cttgatgata caacaatgat tattgtgacc aatacttcgg attattcaga
     4681 agtaaatata gtagctgaaa atacagtcac tgagggtact gatttacttg aaatcaaata
     4741 aatatatttc cctgagtaaa gatggaattt tctttccaaa atcaaataat atagattaat
     4801 caaatatttg agaataacat tttatttaat cttttcatat atcaattgta tgaaaaatta
     4861 ttagaatttt aaaaaatgat aaaaattcaa aaagaaaaaa tagtagttat ttacttgtca
     4921 tgttactaaa taaaaaaata atttaaatat gatatatagt catttattta gtgatttcat
     4981 tctaaaataa agggagaaat gtctatgcta tacggtgcaa ttgaagcagg cggcacaaaa
     5041 tttgtgtgtg ccattggcga tgaagaaatg acgatcaagg aaagagtgag ctttccgaca
     5101 acgacacctg aggaaacaat gcctttagtc attgacttct tcaaacaata ccaagcagat
     5161 ttagcaggga ttgggattgg ctcatttggg cctatcgata tccatcgcga ttccgccact
     5221 tatgggtaca ttacctcgac cccgaaattg gcatggcaaa attttgattt catcggtacc
     5281 atgaaaaaag aatttccgat cccgatttct tggacaacag atgtcaatgc ggctgcctat
     5341 ggtgagtatg tcttcggcag tggcaaagga ttgagcagtg tcgtttacta tacgatcggt
     5401 acgggtgttg gcggcggtgc cttacaagaa gggcgcttta tcgaagggtt tagtcatcca
     5461 gaaatggggc atatgctcgt cgtccctcat ccaaaagatg actttgctgg cagctgtcca
     5521 tttcatggca actgtttaga agggatggcc gctggacccg ccatcgaaaa ccgcttaggg
     5581 aaaaaaggac aagaggttgc agaagatgat ccttattggg aaatcgaagc ctcctatatt
     5641 gctcaatgtg cctacaatac aaccttgatg ttttctccag atgtgatcat ttttggcggt
     5701 ggtgtgatga aacaacgcca tatgctgcaa aacgtccacg acgcatttgc aaaattggtc
     5761 aatgggtatg tcgaaacacc tgagttaagc aaatatatcg tgaccccagc attagaagac
     5821 aacgctggaa cgctcggttg tttggcattg gctcgagaag cggtcttaca ttcataaacg
     5881 aaaaaaggct cttcgacatt tagtgttggt agagaaagat acaactgaaa atttagtcat
     5941 aaccagttag gcagagtgct taactggttt ttgttttact tggaagatca agccttgaat
     6001 gagataaatt cttgctcgaa agttatggaa atttcgatag ccgtaggcca cttgtattgt
     6061 gcaatagttt tttacaaaaa aaagggggtg cggatatttt tttggacctt tttaacaaat
     6121 atatctttgc ttctt
//
LOCUS       DAXQKX010000104         6117 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.107, whole genome shotgun sequence.
ACCESSION   DAXQKX010000104 DAXQKX010000000
VERSION     DAXQKX010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6117)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6117)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6117
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.107"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            174..1478
                     /locus_tag="ACF3MF_002679"
     CDS             174..1478
                     /locus_tag="ACF3MF_002679"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFE3928576.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEDTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            1586..2443
                     /locus_tag="ACF3MF_002680"
     CDS             1586..2443
                     /locus_tag="ACF3MF_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFE3928577.1"
                     /translation="MKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTISSSG
                     AENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELEEALE
                     AAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQQAKE
                     FNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAASFQRI
                     KDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGVLVAA
                     AYGIIRKKK"
     gene            complement(2555..2875)
                     /locus_tag="ACF3MF_002681"
     CDS             complement(2555..2875)
                     /locus_tag="ACF3MF_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HFE3928578.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            3045..4004
                     /locus_tag="ACF3MF_002682"
     CDS             3045..4004
                     /locus_tag="ACF3MF_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFE3928579.1"
                     /translation="MTYTHLTPTELVMIEAYFNQSHSVSKVAHLVQRSRQTIYNVYRF
                     LKSGGSAISYYEQYKKNKRNCGRRPIVLPDGQQEYIQKKVAQGWTPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDPHDLPMKGKRKPNGHKEKRGKQAFRRSIQDRTTDYIQFNHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPAGRQAIDIENRLNQWFQSVPKHLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNK
                     VSETFIQSVASKRNHIPRKSLHYRTPLEVFLSYVGKDDLSSLI"
     gene            4094..4489
                     /gene="dhaM"
                     /locus_tag="ACF3MF_002683"
     CDS             4094..4489
                     /gene="dhaM"
                     /locus_tag="ACF3MF_002683"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HFE3928580.1"
                     /translation="MKKSILLISHSQKVTDGIKEMIEQMQKSEEVQIFSLGGINGEIG
                     SDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEEEQQQRYHLVDAPLVEGA
                     FAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            4464..5474
                     /gene="dhaK"
                     /locus_tag="ACF3MF_002684"
     CDS             4464..5474
                     /gene="dhaK"
                     /locus_tag="ACF3MF_002684"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004371 - glycerone kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HFE3928581.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            5502..6107
                     /gene="dhaL"
                     /locus_tag="ACF3MF_002685"
     CDS             5502..6107
                     /gene="dhaL"
                     /locus_tag="ACF3MF_002685"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaL"
                     /protein_id="HFE3928582.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
BASE COUNT         2055 a         1103 c         1325 g         1634 t
ORIGIN      
        1 tatgaagatg aaaaattgaa aaaaagacaa gaattacttg aagaagtgta tacggaacgt
       61 tttggaacaa aagaagagag agaaacggtc cgtttttatt ctgtctccga agagaaaaat
      121 ctagatacga cattcattgc agatttgtat aaagaaaatg gggtggaact gaaatgatct
      181 caatcaccca tacaggtaat ttattcttag atacttgttt gtctattatg tatttttttc
      241 tcgtttctta tccgatttta ggcggatttg tatggtttat tggtgtctgg tgttatgtgt
      301 ttttatacaa acataagcaa aaagaatggg tagatgttcc cttgagtgtc gaaccgttca
      361 tcacgatcat ggtgccagcc cataatgaag aaattgtgat cgaagataca atcgagtatt
      421 tgatgacgaa attgaattat cacaactatg aggtattagt gacagacgat ggttcaacgg
      481 accaaacacc agaaatatta gctagactga tgaaaaaata cgctaatctt cgtgtggttc
      541 ggatcgaaaa aaataaagga aaagcccacg cgtttaatat cggacttgcc tttgcaaaag
      601 ggaaattgat tttaagcaat gatgcagaca cggtaccgga gccagatgca ctgattaggt
      661 atgtgaatta tttcattcgc cctggtgcaa gacatattgc tgcggtcact gcaaatatgg
      721 atgtccaaaa tcgtaccaaa ttgattgcaa aatctcaaac ggttgaattc tcaagtatcg
      781 tgggcatcat taaacgaaca cagtcagctg ttttcggtgg tctttatgcg tacagtggag
      841 caaatacgat gtatcgaaaa gaagccttga tcgatgtggg cggattcaga caagatcgag
      901 cgacagaaga catcagtatt gcttgggatc atcagttaaa tgactggtta tctgtttttg
      961 ctcctgagat tatctttttc atggaagtac ctgtgacgtt gaagatgcta tatcgacaca
     1021 gaaaacgttg ggcaaaaggt ggaacagaag tctggctgac gaatttcaaa aaagtgatgc
     1081 tccatccttt taaacatatt ggaagaacga tcatcttcat tgatcaaaca ttgagtattg
     1141 tctggtcaat attcttttgt atttccgtag ttctttttgc tggattaatc gggcattatg
     1201 tatatcaagg aaactacgaa cagatttata ttacttttac attcagtttt gtgttcatct
     1261 gctttgaaat ggtcgcagga tttttccagt tgctagcttc gctgattgta gatgatcgac
     1321 gaagaaaatt gaaatacctt cttttcgcac cactatatat gcttttgttc tggatagtga
     1381 acgcgataac gatcgtgacg actttcattc cagcagtcaa aacgatttta ggttatggaa
     1441 gcgggacatg gaaaagcccg gaacgtacaa aaaaataaaa gatgcaccgt tttttagaca
     1501 aacagcctgt tgtgtttatg gttcttccaa acatttttgc ttataataag aaattagtta
     1561 aaaagtagta aggatgggaa aagtgatgaa aaaaagaatg aagccgttaa tctggccaat
     1621 tgctgtttcc agtattttct tattgggaca gacagctttt gcggaaactt ctgaacctgc
     1681 tcaaacagaa ccttcaacaa ccataagctc ttctggtgct gaaaacggtg cctcggaaac
     1741 agaaatgact tccaatgtac cgacagataa ttcaggagaa acgatttcat cttcagaaga
     1801 tacatcaata aatagttcta cctcttctga ccaaatcgat catttgcaag acttggaaaa
     1861 taaaagaaaa gaactcgaag aagcattaga agctgcaaaa aacaaattga aagaagacca
     1921 agcagcaatc gatcaagatt tagctgatct taaaaataaa gtgggaaatg accgtgcaca
     1981 acttgagaaa aagcttgccg aagcgaaagc aaaagcggaa gctgtccaaa cagatcttga
     2041 cgggaagatc caacaagcaa aagaattcaa tcagcaatta aatcaggttg ctcaaacagc
     2101 ttctggaaag ctaagtcaaa ctcaagcgga tatcacagcg gccagtcaag caatccacgg
     2161 aaagatcagc gaagcacaaa cagttgctaa tgattttgaa gcaaaaaaag ctgacttagc
     2221 agctagtttc caacgaataa aagatatttt gcattcggca ggagaaaaat cagtgacctc
     2281 tggaagcacg acagaaacag ttcagcaaac gacagagcca tccaaatcaa caagtcagac
     2341 tttgccaaaa acaaatgaaa aaacagcttc tgtcagttat tccttagcag gggcgggtgt
     2401 gttagtcgca gcagcttacg gaatcatccg caaaaagaaa taaaaaagag aggatgggaa
     2461 ggtagagtac ctcgaagtta gactgaaaaa tctaattctt gagtgccact acatgtccca
     2521 tctctcttta gttattaaaa cagatgtccc ctacttatct cgtggagaca gctgttccac
     2581 tacatgtgac catcagcatg ccattgtcgc tgcctaatac ttcatagtcc atttttacgc
     2641 caatgatcgc atcagctcct aatgcttttg cacgttcggc catttcggca agtgcttctt
     2701 ctcttgcacc cattagttcg ttttcatagc tttttgagcg gccgccaaag atatttcgca
     2761 accccgcctc caagtcttta aatgcatgga tcccagtaat gacctcacca aaaacgatcc
     2821 ctttataagc tactacggct tttccctcta cactgttcgt tgttgttgta atcattcgat
     2881 cactcctctc ttttaattaa agtataacaa acttcaagaa gcactacaca tattttccca
     2941 aaattagaaa tcgccgattg taaaattaag ctagacaact aaaaaagtca tttgtgctac
     3001 actcaaaata gttccgtcga aagaattata aggagtgagt acaaatgacc tatacccatc
     3061 ttacaccaac tgaactcgta atgatagaag cttatttcaa tcaatcacac tctgtttcaa
     3121 aagtagccca tctggtacaa cgttctcgac aaaccattta taatgtctat cgttttctta
     3181 aatctggtgg aagcgcaata agctactatg aacaatataa gaaaaacaaa cgtaactgcg
     3241 gaagacgtcc gattgtgtta ccagatgggc aacaagaata cattcaaaaa aaggtggctc
     3301 aagggtggac tccagatgtc cttattggtc gagcagagtt tcctattgct tgttcggtac
     3361 gtacactata tcggatgttt aaagataaaa cctttgaccc tcacgattta ccaatgaaag
     3421 ggaaaagaaa accaaacgga cataaagaaa aaagaggaaa acaagctttt cgccgttcga
     3481 ttcaggatag aacaactgat tatatacagt tcaatcatga gtttggtcac ctagaaggtg
     3541 acaccattgt cggtggaaaa cataaaagtg cggtgatcac gttagttgag cgattatcta
     3601 aagtgatcat caccttgaaa cccgctggta ggcaagctat agatattgag aatagactga
     3661 atcaatggtt tcaatctgta ccgaaacact tgtttaaatc catcacattt gattgtggaa
     3721 aagagttctc gaattggaaa aagattagta ataccaatga tatttcgatt tatttcgctg
     3781 atccaggaac accttctcaa cgaggactaa atgaacattc gaatggctta ttacgtaaag
     3841 atggcttata taaagctatg gattttaata aggtatccga aacctttatc caatcggtgg
     3901 catcaaaacg aaatcatatt cctagaaaat cattacacta tcgcacacca ttggaagtat
     3961 ttttgagtta cgtaggtaaa gatgatttgt ctagcttaat ttgacaaacg aaaaatttat
     4021 tatatacttg aattgttcat taatgaaagc gaaaccaatc gttagcaact atgtaaaaga
     4081 aaggaagatt cttgtgaaaa aaagtatttt gcttatttct catagtcaaa aagtaacaga
     4141 tggtattaaa gaaatgattg agcagatgca aaaatccgaa gaggtgcaaa ttttttctct
     4201 cggcggaata aatggcgaga tcggatcaga cccgatgaaa atcgtagaag cagtcaatga
     4261 atcaagcgat gcagctagtt attttgtttt tgcggatatc ggtagcgcgg tattgaactc
     4321 ggaactggca aaagacatgt tggaagaaga gcagcagcaa cgttatcatc tggtggatgc
     4381 gcctttagtg gaaggagctt ttgcagcagc catcactgcc ggtataacag atgatactca
     4441 gcaaatctta acagaagcac aaaatgccgg aaagaaagga tgggaataaa ttgaaaaaaa
     4501 tcatgaatga tccaagcaat attgtcgaag aaatgctgga aggattagta aaaagctatc
     4561 cagaacttgt tcatcgtgta gaatcttccc gtgttgtagc caagaatcag aaagcggaac
     4621 aagttggttt ggtttctggt ggaggaagcg gacatgaacc atcccatgcc gggtttgtag
     4681 gggaagggat gttaagtgca gcggtgcttg gtgatgtgtt tacttctcca actccagatc
     4741 agattcagac ggctattaag gaagccgata gtggaaaagg agttttgctg atcgttaaga
     4801 attatacagg ggatgcattg aacttcgata tggcaaagga attagctgct atggacgata
     4861 ttgaagtaga aagtgtgatc gtagatgatg atatcgccgt tgaaaatagt acgtatactg
     4921 ctggaaaacg cggagttgca ggtactgtcc ttgtacacaa aatcgtgggc gatgcagcaa
     4981 gaaacggtgc ttccctagct gagttgaaag aactgggaga aaaggtcgta caggcaacta
     5041 agacgatcgg tctagcgctt cgagcagcaa ctgtaccaga agtagggaaa ccaggattcg
     5101 aactaggaga agatgagatc gagtatggtg ttggtatcca cggtgagcca ggctatcgtc
     5161 gagaaaagat gcagccttct aaagtactgg caaaggaact tgttactaag attttagatg
     5221 attactcgaa tttaccaaaa gaagcaggtg tactagtcaa cggaatgggc gggacgcctt
     5281 tgatggaaca gttcgtgttc atgaatgatg ttttagctct gttggaagaa agaggcgtca
     5341 atgtagtttt ccgaaaagtc ggtaatttta tgacctcact agatatgcaa ggtctttctc
     5401 taacactgat cgacttgacg gagacacaat ggaaagattc tttagaaagc aatgtacaga
     5461 cgatttcatg gtaaaaaatc tcaagataaa agggtgataa tatgaaacta accgttcaag
     5521 aaatccaaga atggctcacg caatttgcag aggcaatcaa tcagaacaaa caatatctca
     5581 gtgatctaga taccccgatt ggcgatggag accatggaaa taacatggga agaggggttt
     5641 cagcttatga agaagctttt caagccgatc atcctgaaac aatcagcgat acattcaaag
     5701 tattctctat ggcgatgata tcgaaagtcg gtggggcttc tggtccgtta tacggatctg
     5761 cattcatgaa catgatgaaa gcgacaaaag aggtcgattc tattgattct caagaaaaat
     5821 taggcgaagt gatcgagcag ggaacagcgg gtattcaaag ccgaggaaag gcagaagctg
     5881 acgataaaac gatgttagat gtttggctgc cagtcacaga ggcattgaag gcagggaatt
     5941 taacaaaaga aatcattgac caggcaaaag aacacaccaa agtcttggta gctaaaaaag
     6001 gacgagcttc ctatctagga gagcgtgcaa tcggacatat cgacccagga gctgcttcta
     6061 gtgccatttt attttcaacg cttttagatg tgatcaatca accttaagtt caataaa
//
LOCUS       DAXQKX010000105         5969 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.108, whole genome shotgun sequence.
ACCESSION   DAXQKX010000105 DAXQKX010000000
VERSION     DAXQKX010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5969
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.108"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..451)
                     /locus_tag="ACF3MF_002686"
     CDS             complement(<1..451)
                     /locus_tag="ACF3MF_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFE3928583.1"
                     /translation="MKYKEMFVPSLIQLAVEVKNKEEAFLIAAQQLEKMGYVNENYLN
                     GLIAREREFPTGLITKYLNIALPHSECEYVEKPFVFVMQLKNPIYFYQMGDNQEMTVE
                     NLFFLGIKEPKEQVGLLQAFMNLFMDETFVENYKKQETPQNIYELITN"
     gene            675..1466
                     /locus_tag="ACF3MF_002687"
     CDS             675..1466
                     /locus_tag="ACF3MF_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFE3928584.1"
                     /translation="MLKKERQEQIITLLEKDFYLTNSEIANKLGVSEMTIRRDVTELA
                     KKNKVKKLYGGVERKEPYNRELSTQEKIDTNVAEKKYIGQVMNSMIPDNSTIYVGAGT
                     TILYALPFIQKKNLFVITNSLIAFNYLKNHTSYRILLTGGEFSPITEEFIGEVAERSF
                     ESLNVDISFAATNGIFDNNVTTAQFIEGNIQNAALNAAKIKCIVADYSKLNKSDVYTF
                     RKLTDFDYLITDNHLSEQDFNHYSKYLTILKEPKNDTDNHDEPIH"
     gene            1432..2385
                     /locus_tag="ACF3MF_002688"
     CDS             1432..2385
                     /locus_tag="ACF3MF_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HFE3928585.1"
                     /translation="MILTITMNPSIDSIYFTKHFELGTMTRFDSPVRYVGGKGINCGR
                     ASALLGSSVILTGFLGGYFGSMIQDMLKNENLFDLHFLPIAEESRGAVTIMHDDETQT
                     ELVEAGPEIADTTIKKLMNDIKLISKNNYLSVITINGSVNNPDPFLYAKLLQYIKEQI
                     DPSTYILMDISGQHLREVLASKYKPMFIKPNIHEFSDIIHQKITQKSDIKHHLKTNPL
                     FKDIDVIMISCGSYGAVVKVKEEFWNVEIPKIPIINTTGSGDATVGGFAHSLEQNYPL
                     KECVRYAMACGMSNAQQSEVGKVIPADVKNLAKSIKITEMK"
     gene            complement(2783..3757)
                     /locus_tag="ACF3MF_002689"
     CDS             complement(2783..3757)
                     /locus_tag="ACF3MF_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFE3928586.1"
                     /translation="MNKELNITQEWDKVFPKSNQVNHRKVSFPNRFGITLVADLYEPK
                     EVSEKKLPAIAVSGPFGAVKEQSSGLYAQTMAERGFLTIAFDPSFTGESGGVPRYVAS
                     PDINTEDFQAAVDFLSVQKNVNPERIGIIGICGWGGMALNAAAIDTRVKATVVSTMYD
                     MTRVTANGYFDVMDENARYEMREELNAQRIIDFKQGDYARAGGVVDPLPEDAPQFVKD
                     YNAYYKTDRGYHVRSLNSNDGWNRTSGLSLMNAKLLHYIPEIRHAVLVIHGEKAHSRY
                     FGEDAFKELKGDNKELMIIPGASHTDLYDQTDIIPFEKMATFFEENLV"
     gene            3872..4306
                     /locus_tag="ACF3MF_002690"
     CDS             3872..4306
                     /locus_tag="ACF3MF_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFE3928587.1"
                     /translation="MYSIGQVSEMFGLPVSTLRYYDKEGLFPDIQRVSGIRKFSENEL
                     EALRVIDCLKKSGLEIKDIKQFMEWSKEGSKTFEVRKELFEKQKEVVEKEIAKLERVL
                     AMLNYKSWYYEEAIKAGNEEAVLTMIPDDLPQHVKEAYVHSH"
     gene            complement(4431..5453)
                     /locus_tag="ACF3MF_002691"
     CDS             complement(4431..5453)
                     /locus_tag="ACF3MF_002691"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HFE3928588.1"
                     /translation="MKKIGFLSFGHWMEQGSLVKSAQDAYLQSIDLAVEAEKIGVDGA
                     FFRVHHFAPQIGSPFPLLAAIGAKTSKIEIGTGLIDMRYENPYYMAENAGLTDIITQG
                     RVQLGVGRGSPEQVLDGWKYFGYDYSEEEIKEVTRERTLEFLELLEGKPFEEPNPQPM
                     FPQGSGKLRIEPYSEGLRQRIWWGAGSQQTAIWAAQHGMNLQSSTLVNYESHEPFHIQ
                     QANQLRAYKEAWKQAGHDFEPRTLVTRSIQPITTDLDRRLFGQDGSPQQDAVGYLAYH
                     RNPTIFGKTFAGEPDQLIKELAEDEAIKEADTVLVTIPNTLGVEYNMHLLETIVKDIA
                     PELGWR"
     gene            5845..>5969
                     /locus_tag="ACF3MF_002692"
     CDS             5845..>5969
                     /locus_tag="ACF3MF_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (thioredoxin)"
                     /protein_id="HFE3928589.1"
                     /translation="MKKIYFLCTGNSCRSQIAEGYARKYLSPSMFEIRSAGIETHG"
BASE COUNT         1876 a         1124 c         1028 g         1941 t
ORIGIN      
        1 aatttgtaat aagttcgtat atgttttgcg gtgtttcttg tttcttgtaa ttttccacga
       61 atgtttcatc catgaataaa ttcataaacg cttgaagtaa tcctacttgt tcttttggtt
      121 ctttgattcc taaaaaaaat agattttcta cagtcatttc ctgattatcc cccatttgat
      181 aaaaataaat tgggttcttc agctgcataa caaaaacaaa tggcttttcg acatattcac
      241 attccgaatg tggcagcgcg atatttaaat acttagtaat caatccagta ggaaattctc
      301 tttctcttgc aatcagtcca ttcaaataat tctcattgac gtaccccatt ttttctaatt
      361 gttgtgcagc gattaaaaaa gcttcttctt tattttttac ttctaccgct aattgaatca
      421 aactaggaac gaacatctct ttatatttca ttccaacctc ctcctttttg attaagtttg
      481 ttaatttatt gttctactaa gttcatcttt gttttacaag aacattatat ttctgttagt
      541 ttgttttgtc aacgctttta aaagaaattt attttgttaa atttgatcta cttgaaaata
      601 aaatcgttta tctatataat taagaagaac aaagtcgaac aaaaattgac ttttatgtta
      661 aaggagtaat tcatatgctg aaaaaagaaa gacaagaaca aatcattaca ttattagaga
      721 aagattttta tttaactaat tcagaaatcg ctaacaaatt aggcgtatca gaaatgacca
      781 tacgccgaga tgtcactgaa ttagcaaaaa aaaataaagt aaaaaagcta tatggtggcg
      841 ttgaacgaaa ggaaccttat aatcgagaac tatcgactca agaaaagatt gatacgaatg
      901 tagccgaaaa aaaatatatt ggtcaagtca tgaacagtat gattcccgat aattctacta
      961 tttatgtcgg tgctggaaca acgatcctat atgcacttcc tttcattcaa aagaaaaatc
     1021 tatttgtaat tacaaacagt ttgattgctt tcaactattt aaagaatcat acaagttatc
     1081 ggattttact tactggtggc gaattttctc ctattacaga agagttcatt ggggaagttg
     1141 cagaaagatc ttttgaaagt ttgaatgtcg atatctcttt cgctgcaaca aacggcatat
     1201 ttgataacaa tgtgacaacc gctcaattta ttgagggaaa tattcagaac gcagcgctca
     1261 atgcagcaaa aatcaaatgc attgttgcag attattcaaa attaaataaa tcagacgtct
     1321 atacttttag aaaattaacc gattttgatt atctaataac cgataatcat ttatcagaac
     1381 aggatttcaa tcattattca aaatacttaa caatattaaa ggagcccaaa aatgatactg
     1441 acaatcacga tgaacccatc cattgattcc atttatttta caaaacactt tgaattaggt
     1501 acgatgacac gctttgattc tccggtacgc tatgtaggcg gcaagggaat caattgcgga
     1561 cgagcttctg ctctactagg ttcatcagtt attttaacag ggtttttggg cggttatttt
     1621 ggcagtatga ttcaagatat gctgaaaaat gaaaatttgt ttgatttgca ttttttacct
     1681 attgcagaag aatcaagagg tgccgtcacg atcatgcatg atgatgaaac gcagacagag
     1741 ctagtggaag ctggtcctga aatagcagat actactatca aaaaattaat gaatgatatc
     1801 aaactaatca gtaaaaataa ttacctttca gtcattacaa taaatggttc tgttaacaat
     1861 ccagatccct ttttgtatgc taaattatta caatatatca aagaacaaat agatccttcc
     1921 acctatatat taatggatat atctggacaa catctccgtg aagtcttagc aagtaagtat
     1981 aaaccgatgt tcatcaaacc taatatccat gagttttcag atatcatcca tcaaaaaatt
     2041 actcaaaaaa gcgacataaa acaccatcta aaaacaaatc cactatttaa agatatcgat
     2101 gttatcatga tttcttgcgg ctcgtatggt gcagtagtca aagtaaaaga agaattttgg
     2161 aatgttgaga tccctaagat tcctatcatt aatacaacag gctctgggga tgccactgtt
     2221 ggaggttttg ctcattcatt agaacagaat tatcctttaa aagaatgtgt aaggtacgca
     2281 atggcttgcg gcatgtcgaa tgcacagcaa tcagaagtcg ggaaagttat tccagctgat
     2341 gtaaaaaatt tagcaaaaag cattaaaatc acagaaatga aataaatagt acaaagtaaa
     2401 taattgttta tatgaaatga gacacaaaga gactgtgaca aaaaacgtgt gtaccgaccc
     2461 ccaaaagtta gattttttgg tctaactttt gggagtcgat acattgtcac agtccttttt
     2521 tcgaataaac ggtgttctcc tgccaactcc tcggtcacaa gtcacaatat tcaacaaaca
     2581 tgagaagcta ttttttgaaa ttgctccttg tgactcagag ttaaacggca ggctcacgac
     2641 ctcttggtat aaacggtgtt caaaagcttg catctacgct aatgagtcca accaagtcaa
     2701 aaatgaggag cttttttggc tgtccttatt acttgatgca gggcagtttt ttcataatct
     2761 cttttagatt aaatcctttt ggttacacaa ggttctcttc aaagaatgtt gccatttttt
     2821 caaatggaat gatgtctgtc tggtcgtata gatctgtatg ggatgctcct ggaatgatca
     2881 tgagttcctt gttgtcacct tttagttctt tgaaagcgtc ctccccaaag taacgtgaat
     2941 gagctttttc cccgtgaatg actaagactg catgacggat ttctggaata taatgcaata
     3001 gttttgcatt cataagtgac aaccctgatg tcctattcca accatcattg gagtttaaag
     3061 aacggacatg atatccgcgg tctgttttat aatacgcatt atagtctttg acaaattgag
     3121 gagcatcttc aggcaacgga tcaaccacac ctccagcacg tgcgtagtcc ccttgtttga
     3181 aatcaatgat gcgttgtgca tttaattctt cacgcatttc atatcgggca ttttcatcca
     3241 taacatcgaa gtagccattt gctgttactc gagtcatgtc atacattgtg gaaacaactg
     3301 ttgctttgac ccgcgtatcg atagctgctg cattcaatgc catacctccc catccacaaa
     3361 taccaatgat tccgattctc tcagggttta catttttttg tacagataaa aagtctactg
     3421 ccgcttggaa atcttccgta ttgatatcag gcgaagcaac atatcgaggt actcctccgc
     3481 tttctcctgt aaacgatgga tcaaacgcaa tcgttaaaaa gcctctttca gccatcgtct
     3541 gcgcatatag accagacgat tgttccttca ctgcaccaaa tggcccgctc acagcgattg
     3601 ccggcaattt cttttcactt acttcttttg gttcatataa atcagcgact aatgtgatac
     3661 caaaacgatt cgggaagctc acctttcgat gattgacttg attgcttttt ggaaatactt
     3721 tgtcccattc ttgtgtgatg tttaattctt tattcatatt ctagactctc ctttgatcaa
     3781 aattgacatt tgtttttgaa tgtattatta tgataaaact taaacttgac tttaggtcaa
     3841 ggtaaaaatt ttattttagg aggatttttt tatgtattcc attggacaag tgtctgaaat
     3901 gtttggattg cctgtttcta ctttacgtta ttacgacaaa gagggattat ttcctgatat
     3961 ccagcgtgtt tctggtatta gaaaattttc agagaatgag ttagaggctt taagagtcat
     4021 tgactgtttg aaaaaatctg gtttagaaat aaaagacatt aagcaattca tggaatggag
     4081 caaagaaggc agtaagacat ttgaggttcg taaagaacta tttgaaaaac aaaaagaagt
     4141 agtagaaaaa gaaatagcaa aattagaaag agtactcgct atgctaaact acaaaagctg
     4201 gtactatgaa gaagcaataa aagccggcaa tgaagaagcc gtattgacaa tgattcctga
     4261 tgatttaccc caacatgtaa aagaagctta tgtacattct cattgaacaa acggataact
     4321 cactctcctt ctctatgaac ttcatgaaaa catgaataaa cacctctaac tgattgttag
     4381 aagtgtttat tttttcactc aagtatcctg cacttacaaa aatatccttt ttaccgccat
     4441 cctaattctg gagcgatatc ttttacgatt gtttcaagca agtgcatgtt atattctacc
     4501 cccaaagtat taggaatcgt gacaagtact gtgtctgctt ctttgattgc ttcatcttca
     4561 gctagctcct tgattaattg atcaggttca ccagcaaaag tttttccaaa aatcgttggg
     4621 tttcggtgat aagcaagata gccgacagca tcttgttgcg gactaccgtc ttgtccaaat
     4681 aagcgtcgat ccaaatcagt ggtgattggc tgaatcgagc gagtaactaa tgttcttggt
     4741 tcaaaatcat gacctgcttg cttccacgct tctttatacg cacgtaattg gtttgcttgt
     4801 tggatatgga atggctcgtg ggattcgtaa ttgactaatg tagatgattg cagattcatt
     4861 ccatgttgtg ctgcccagat tgccgtttgc tgcgaaccag ctccccacca gattctttgt
     4921 cgtaatcctt ctgaataagg ttctatccgt aattttcctg atccttgtgg gaacattggt
     4981 tgaggatttg gttcttcaaa tggttttcct tcaagtaatt ccaagaattc aagggtgcgt
     5041 tcccgtgtta cctctttgat ttcttcttca ctgtaatcat aaccaaagta tttccagcca
     5101 tctagaactt gttcaggtga accacgcccc actcctagtt gcactcttcc ttgcgtgatg
     5161 atatctgtca atccggcatt ttctgccata taataagggt tttcatatcg catatcaata
     5221 agtcctgtac cgatttcaat cttacttgtc tttgcgccga ttgccgctag caaaggaaac
     5281 ggcgacccaa tctgaggggc aaaatgatgt acgcggaaaa acgctccgtc cactccgatt
     5341 ttttctgctt ccaccgctaa atcaatcgat tgcaaataag catcttgagc tgatttcaca
     5401 agcgatcctt gctccatcca atgtccaaag cttaaaaagc cgattttttt caaggtaatg
     5461 acctccttta aacctacaaa aatggaaggt tttttatttt taatatgaac tgattctact
     5521 actttttttc ttaaaagacg aataattgtt ctcgcctcac aatcaagaaa tgtatcggct
     5581 tactacaccc ctactttctt catcatctgc cgtgtcttaa tctcttttaa cagtctgtta
     5641 catcgttgat ttttgactca aaatgattgt ttctaacatg tatttatggt aaaaaagaca
     5701 agattagttc tttgtacaca tcgatttata cgctgaacaa aaagaaatat ataaactaag
     5761 aaacccattg ttttttcgct ccatcacata gagtttactt tagataaaca gtgacattta
     5821 ctaatccata acggaggaaa tcaaatgaaa aaaatctatt tcttatgtac gggcaattca
     5881 tgccgcagtc aaatagcaga aggctacgcg cgtaaatact tgtctccttc aatgtttgag
     5941 ataagaagtg cggggatcga gacacatgg
//
LOCUS       DAXQKX010000106         5930 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.109, whole genome shotgun sequence.
ACCESSION   DAXQKX010000106 DAXQKX010000000
VERSION     DAXQKX010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5930
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.109"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..500)
                     /locus_tag="ACF3MF_002693"
     CDS             complement(<1..500)
                     /locus_tag="ACF3MF_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928590.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWV"
     gene            complement(510..1670)
                     /locus_tag="ACF3MF_002694"
     CDS             complement(510..1670)
                     /locus_tag="ACF3MF_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFE3928591.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            complement(1670..2356)
                     /locus_tag="ACF3MF_002695"
     CDS             complement(1670..2356)
                     /locus_tag="ACF3MF_002695"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0046797 - viral procapsid maturation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head maturation protease, ClpP-related"
                     /protein_id="HFE3928592.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            complement(2319..3497)
                     /locus_tag="ACF3MF_002696"
     CDS             complement(2319..3497)
                     /locus_tag="ACF3MF_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFE3928593.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            complement(3517..5211)
                     /locus_tag="ACF3MF_002697"
     CDS             complement(3517..5211)
                     /locus_tag="ACF3MF_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HFE3928594.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            complement(5189..5503)
                     /locus_tag="ACF3MF_002698"
     CDS             complement(5189..5503)
                     /locus_tag="ACF3MF_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HFE3928595.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            complement(5606..5887)
                     /locus_tag="ACF3MF_002699"
     CDS             complement(5606..5887)
                     /locus_tag="ACF3MF_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928596.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
BASE COUNT         1726 a         1242 c          846 g         2116 t
ORIGIN      
        1 acccactgtg cgcctcctga attagtgttt atagtttcca aagattctac tgtaacattt
       61 acaatgtttg ccatatcttt tagaatattt tctccgtttt cacagcttct aatataatca
      121 agacttagat aactacagca gtcgctacaa taccaaacat catctttaga aggcaatttg
      181 cgcaaattaa ttcttttatt gaaaatgaca tccgaatcga tatagaaata tcggtcgtcc
      241 tcacgcgaat gatcttcttc taaatatttc caccataaat atggtttaat cgaaggaata
      301 tactctttgt cgtcccgcag atcatcgtac acatgaactt caacaccata ttccttctca
      361 aaaaaaatag gaatctgatc atcgtgtctg ctgaaaagca atacgatatc tttgattcct
      421 agtttcttca gattagttaa acaaacttca agctcccatt taaaccgatt gattgccggc
      481 tgacaaagaa tatacttcat tctgatcacc tacgcttgtg ttgtagttgt tgtggttgtt
      541 ggttttgtag ttgtagtagt agttcccaaa gcgctaatat ctaatacaat gaaactatcg
      601 ttacgtttag gttgaccgtt tgcatattgt ttagctagat aaatgcgttc gtcttcaaca
      661 aaatggtatt catctgaagc ttcaattttt agtgtagatc ctacacccat gaagtaatct
      721 gaggctaccc caataactgc ttttccttct ggcacagccg ttgactgcaa atctgaaact
      781 ggtactggca atacttgtac gtattctcca ttagcagtta gtacagtctt agctgggaat
      841 actttagacc agtaatcagt tggattcaca attaggacca catcagaagg attcacatta
      901 cgataaatcg gatcattcac accttcgata ttgaattttg atagtcgcgc catcaaaccg
      961 cccatagtta cagcatctaa agctgtaata ggttctgctt ttttttcagc atattctccg
     1021 ctagtttgtt tgctcatgtc acgcatcatt ccgactggca tatctttacc agtaccatca
     1081 acaattgctt gttctaatgc aattctcaat gattctacta aaacagtacg gacataacga
     1141 tctaaccata ctggacctaa atcaagcatt gccttacata caggaatata acctgatagc
     1201 ttgaactgct tcatgttaat tacatcaaag ccattatcta aaactttttt aacagcttcg
     1261 caaagtttac cccaccatgc tggattgact ccacgtgaca caatccattc tgttacacca
     1321 gttgtgttaa caaaagtaat tttttgcaat agtggatgag attgttctaa atcttcaaat
     1381 acacgttcaa atacagtagc tggcactaat tcttcgaccc ctgcaaaacc ttcgtttttc
     1441 actacttcgt tatagaattt tgtttcttgt gtagttaata cacgctgacc acggttcatt
     1501 aatactaatt gatcttgatt ttttgctgtt gcttcttcta aaattttatc ctgaatttcc
     1561 ttagataagc ttaccatagc tgcgctaaaa gattcttcgt taccatcttt aaaagctttc
     1621 atcaattggt cgcttgcagc tgttacacct tttaaatttt taactgtcat tattttacat
     1681 ctccttgtcc aaatgtttta tttaatgctg ctgtaaatgc agcaattttt tctgctcttt
     1741 tttctttaac gtcattcaaa atttcttcaa cgctttgttc ttttttagct tcagtacctg
     1801 agctattttc tgcatcgata atttcatcga ccaatccata actcaaagct gtttctgcat
     1861 ccataaacga ttctttttca agaagttctt gcaatgcttc atctgtgcca ttgaatcgtg
     1921 ttttatatga agcctttacc gatttatcaa ttgattccag ttggtcagca atcgtacgga
     1981 agtcatcgac atttccttct ccgtatgtgg aagcgcggtg aatcatcaat tgtgcattgt
     2041 tgtagatttt tatagtatcg ccagccattg cgataattga agcagcacta gcggctaagc
     2101 cgttaatcac aacgttaact tttgctttat ttgacttaag taagttccca atagcaatcc
     2161 cttgaaatac gtctccaccg tttgaattaa ttactacttc aatttcttct tgatcaccta
     2221 gactatccaa aatatttttg attcccttgt cagtattccc ttcaaagaac caactagaac
     2281 caataaatcc ctgaataaaa atttgcggta ctgcgccttc attctttact gctagaaatg
     2341 ttttcattgt cgtcattcgc ctcacctcct ttcgatactt gttgattgtt tttagttata
     2401 aatatttcat ctgccatcgc cttatcagag cgatcatttc caacgcgttc tcttccttcg
     2461 ttgattgtaa atactccatt tctaatgcct acatcaatag cgtcaaccaa atctttgaag
     2521 ctagtaatct tgatcatagt tgtatccaca cgtacaaaat tccctgacaa gtattcttct
     2581 acttcataga gactagcgtt aaacgcatcc tgaataagtt cagcaatcgg tatgatttcg
     2641 aacattaaaa aagcgtccac ttgatccgat aacccactca tgtctccctt tagtaggttt
     2701 ttcggaacgt gaaacgctgc tgctgtcatc tcaaagatgt cgtctattaa gttttttata
     2761 tctcttgaat tgctttggaa gtttccgctg aaatcttcta atgtgtactc attttgtaat
     2821 tgaaataccg cacctgcatt atcagcttcc ataaaagcct taaattgtga tgtcatcatt
     2881 ttattgattt gatcttgtgt tgtattgtct tgcggtcgga ataaattccc tttcagtacg
     2941 tatctacgag cgttagagcg cttgtaaaca ttcatggcac tagaaatgag tttcccatac
     3001 gcttgataat acgcatcgac tagttgccta atttgttgat ctgcgtattt tatatagata
     3061 acatcacttt ctagaaattc tctatcaagg actatgttgt taatttgcac ttgagaaaac
     3121 acatcatctt tcaatgcata ttctgtgaca tcccaactat ccgcaataaa tatttcgcta
     3181 gaattattag acggagaaac gatcaatact tcattgtaga atattaatct cctgatcagt
     3241 ttttttctaa attctgttgc attatttttc ttattaggag ctacattcag cctatagtaa
     3301 agatcattct ttttattttt tccatcttca tatgacttga attccgcttt actcatcgca
     3361 tttgcaatca aatcaataca agtttcaatc gcaaattttc gatacacaaa atcaacttgc
     3421 aatttacaaa agtattcttc taaaggaacc gttgcttttt ttgtgaagta tcctaccgcc
     3481 ttttgaaaaa tccccacttt ctcacctcct ttcaagttag aatactagag gagtaaatcc
     3541 agttcctgta ttttctactg agctatttgt gactgttaca ggagcagaat cataaatatc
     3601 atctaaaaaa ttcaaaccat gaaggaatga aaaaaagcca tccgtttttc tagtttcagg
     3661 ttctattttt tcatagcgta tatttccatt agaaatatgc tcttcatata cattcatgca
     3721 ataccaacgc ataatcgcat cgtcaccaaa aaataaacgt tgattaataa aaaggtcatc
     3781 aaccagatct tttaacatac catgtgtaac agatccgctt cgaacaattt ccacagtaaa
     3841 acctgcttct tctaaagcgg gcttcaatat ttttgcacgg tacatatcca tagcgatttt
     3901 tttaatataa tatttattac tcatttcaag aaaccaacct acaatataat cagcttctat
     3961 attttttcca tgaacgatct gtgattttcc ttgatctata gaaatatcta taacctctcg
     4021 tttgatgttt tgtaatcgaa gggctgattc gtggataaaa gtatgttgtg taaaataaac
     4081 atctttatcg tattttccta gcaacccaac gctggcaaaa tctcgtctat cagcaaaatc
     4141 gactgttcct atcacttcat ccattttttc aggaaattct ttttctttcg tatgcagaac
     4201 atcatcatat gaagcaacag caaatcgtgt atcttccata ggtctgttca ttcgtttggt
     4261 catgaacgta agtcttaaac cagcattacg ttgcatttga gagtattctt gaaacatttt
     4321 ccgttttaaa tctgcattgt aattaatagt tggacaagct ttttcccaca tgtcgggatc
     4381 atcaacttca ttatcgttat ccaagcgaca aataaatgga aacaaactag aaaattctgc
     4441 tccatccttg tcaattccaa gttctccaga aagaatcatt tttgattctt ctataatgtc
     4501 atcaagcgga ccaccacgaa catgaccatt agttgtatca taaaattctc tataatctcg
     4561 aattttacca ccaccagaag tagccacatt tatcattgaa taatcttcat tttcgtgaat
     4621 ttcatcaaag cggtttgcac ctggtcgctt cccatctttt gttctagcat ttgccgtgtt
     4681 ataacgaagt ttgctgtttg tagcgatatt ttgaataact tccttcgtag ctttaaatac
     4741 ttttttatct aaatcaggat gatctttaat tactttaaat acatcatcaa aactagtctt
     4801 tgcttggctt tcattattgg catagatatc aatatcataa tttttaatac cgtgtttagc
     4861 ggttagtaga aagaagttgt tccaagaagc aaaaccagtt ttaccattac cacgtcccat
     4921 taatgaaaga tatctattga acactagtgt tttatctttt ttccatcgaa caccataaat
     4981 aaaacattgt agaaattttt cccacggaat taattcgaat ggaaagtatt gtgctggtat
     5041 attgattgaa tcctctacca tctgcttatc gaagtaaata tcttctctag taaagactct
     5101 ttcttctaga taatttttta gcaataattg ctctttgcat accttgatag tgccttcttc
     5161 tatagctttg aaccaatttt caatatgctt ataactcagg aattgattca tttgcttcac
     5221 ctaccaattc aggagtaatg gcaagtttat ccaacatcaa tcccatttgt ttgttgacag
     5281 aaacaagcaa cgctactgat tcattctttt taccattctc cagtctaatg ccgttctcgg
     5341 atatatcttc ttccagtgat atcgccgttt cccataaact gatataacga tcaacattat
     5401 ctaagaatgg ctcaatattt gttttctgac tttccaattg gcttattaaa gagcggcgta
     5461 atttttctct gtagcgattt tgagacaatt cgtttttaaa cattttagcc ctcctttcat
     5521 gataaagttc gaaaaaatct cttttcctga cagccccctc cgtttcatca cccccaaaaa
     5581 atttgcgatt tattttaagg gggggttatc tcaccatcgg aatgaaagct tcagcgaagt
     5641 caatgtaata attaatctct tcaatactat atccaaaaac attttttatt ctttcgacgt
     5701 tattatcttt attcaacgct tctcttactt gattcacttt gtatttacta caacagttat
     5761 ctgataacag atccctaata cctacatagc gaacgtatat caaacgttta attaatccct
     5821 gagtataaga tgaatactct tcaatctttt ctgtatcata ctctctgcca ttatcattga
     5881 tgatcatgca cttaccacct ttcacttgca tcgaagttag caaagctttc
//
LOCUS       DAXQKX010000107         5630 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.110, whole genome shotgun sequence.
ACCESSION   DAXQKX010000107 DAXQKX010000000
VERSION     DAXQKX010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5630
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.110"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..683)
                     /locus_tag="ACF3MF_002700"
     CDS             complement(<1..683)
                     /locus_tag="ACF3MF_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coiled-coil domain-containing protein"
                     /protein_id="HFE3928597.1"
                     /translation="MKKTFISTSVIVFSLFFSNGLLAKAQTIEEKIKEKDDKIEAIVK
                     NKESAENYLTDLDNKITQLEKEYKKVLVEKNTSEKKLTEINQKITALEERIRLRNKLI
                     EEQARNAQVNQKSDSIISVMVNAESLSDAVTAAIGMTKLISASNEIMQAQIDDKENLD
                     ELKKEAEKKVTDAEKETRSLEEKENDLIEAKLTQSIKINEISASLATEQSEKAKFENQ
                     KQEAEKRRE"
     gene            955..1362
                     /locus_tag="ACF3MF_002701"
     CDS             955..1362
                     /locus_tag="ACF3MF_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HFE3928598.1"
                     /translation="MNKTLRLMKPWDYLIITAVIMASFVPYLLFDTNNDENNNRESTD
                     VIAVVKIDGEVVDKFNLSQVNESFEKTYYPQKGKYNIIEVAPGKIRVKEDNSPDQIAV
                     RTGWISRPGEMSICLPHKLIVEILGVEENPLIY"
     gene            1541..2824
                     /locus_tag="ACF3MF_002702"
     CDS             1541..2824
                     /locus_tag="ACF3MF_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HFE3928599.1"
                     /translation="MVGVITVDNTYLTDVFNQYKLRENLLYQTWFIKSEKRLKAFKKV
                     RKYVQVLIKHVNNGTFPTDFKNSALEDIMNVIAEQTEIFKGAKHAFMWKPKLRIPDIY
                     ENRENQLAFSLCLDQILKANQEIKMLFAVNILAEKKIRGLGPAVANILYFLEPTIFPP
                     FNTAIVNGYNYLTGSKIRLGKWEDYFKLRDGMIELNCLGGLFSKDLGAISAFLFDIGK
                     LNYIVRENEEEYVRISESNTQKLIKQKLEKEDGKNVHQKIQYILATLGNEIGYHAWIA
                     SNDHNRIVDGNRLGDVSIPLLPETIYQLPNPLSRTIGLIDVIWFSKNGEPICAFEVEK
                     STSIISGMNRMDDLYSIHQENLMMYIVSPDQREEEIRAQFNRPHYMRNQNLHDHLRYI
                     LFTDLEKHANFMKKFGKDFTILAPISHYPSGELVR"
     gene            3535..4248
                     /locus_tag="ACF3MF_002703"
     CDS             3535..4248
                     /locus_tag="ACF3MF_002703"
                     /inference="COORDINATES: protein motif:HMM:NF017416.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFE3928600.1"
                     /translation="MYTNYNMNQLTLDLSTSFSPKENHVAVFIHELVEALQINDPYLF
                     GRPREYDLGAMMKVVLFAYTRETFTSRKIERLAEENLYARWLTQERVPTYRTIARFCV
                     SNDVQELTNKGLDQLTEYLRARNLIDDALFIDGTKILADANKYSFVWKKNTIRFDQMN
                     REKLLTMMTELKEAYALKQIPEGTTLTVDMIDELLTRMELRLDELENEVEATKRLSPN
                     PAKQQRRTLKSQVRKLNAK"
     gene            4282..5085
                     /locus_tag="ACF3MF_002704"
     CDS             4282..5085
                     /locus_tag="ACF3MF_002704"
                     /inference="COORDINATES: protein motif:HMM:NF013752.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFE3928601.1"
                     /translation="MYGTRNSYSKTDHDATFMRVKEDHMKNVQLKPAYNLQIATCNQF
                     VLGYDVFQNPTDTKTLKPLLEKMKTAQKSPHYLVADAGYGSESNYRYIEDELPQHTAL
                     IPYGTMFKEQSKKWQTDDRKVMNWVYEPNEDFYIDPKGVRFNFHAYRQRTDADGFVRD
                     FKEYQAEKTDANQALIPEALTPKGNRRKITVNPSWEYHKEKQKERLSTPDIQKIYGRR
                     KVDVETVFRFMQACSGFTRYTVRGLEKVRKQTGLLITAINMMKLTKIGT"
     gene            complement(5199..5378)
                     /locus_tag="ACF3MF_002705"
     CDS             complement(5199..5378)
                     /locus_tag="ACF3MF_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2933 domain-containing protein"
                     /protein_id="HFE3928602.1"
                     /translation="MQWLLLLLCPIMMIFMMRGMHSGSHNEKDDEQLKQDLENLKEQN
                     DILSSELSDLKSRLK"
     gene            complement(5381..5605)
                     /locus_tag="ACF3MF_002706"
     CDS             complement(5381..5605)
                     /locus_tag="ACF3MF_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2933 domain-containing protein"
                     /protein_id="HFE3928603.1"
                     /translation="MEALLNLLPLLLLLICPISMMFMHKGHGHAGHHHMHGEDHSKHT
                     GSENDIASLKIQTEQLKEEVATLKNLVKER"
BASE COUNT         1875 a          949 c         1022 g         1784 t
ORIGIN      
        1 tcctcccttc ttttttcagc ttcttgtttt tgattttcaa attttgcttt ttcggattgc
       61 tctgtcgcca aagaagcgga tatctcattg atttttatac tttgagttaa tttggcttct
      121 ataaggtcat tttctttctc ttcgagagat cgagtttctt tttccgcatc tgtaactttt
      181 ttctcagctt ctttttttaa ttcatctaaa ttttctttat catctatctg ggcctgcata
      241 atctcattac tagcagaaat aagcttagtc ataccaatgg ctgctgtgac tgcatctgat
      301 aatgattcgg catttaccat gacagatatt atagagtcac ttttttgatt tacttgtgca
      361 ttcctagcct gctcttcgat aagtttattc ctaaggcgta ttctttcctc aagagcagta
      421 attttctgat taatctcggt aagtttcttc tcagatgtgt ttttttccac tagcactttt
      481 ttatattctt tttctagctg agttattttg ttatctaaat cagtaagata attttcagct
      541 gattctttat tttttacaat cgcttcaatt ttatcatctt tttctttgat tttttcctct
      601 atagtctgtg ctttagctaa gagaccatta ctaaaaaata gcgaaaacac aatgacagag
      661 gtagatataa atgttttttt caaattgatt tttcacttcc cttattttat ttgtgaagaa
      721 acattttaca taatattctc ctctctattt tatcgttgct acaggttcta ctaggaattg
      781 aaattggaat tactatacaa aaagtaatag gatccatatg ctatatttca atttaataga
      841 cagcttcaaa ataactaaaa cttatggaga ttttatggag catatacata cctacataaa
      901 attcacacaa ctgtaaagta tgatatcaaa agttaataca ggagaacgaa tttagtgaat
      961 aaaacattga gactcatgaa accttgggac tatttaatta ttactgcggt cattatggca
     1021 tcattcgtac catatttact atttgatact aataatgatg aaaataataa tagggaaagt
     1081 acagatgtaa ttgcagttgt taaaatagat ggagaagttg tagacaaatt taacttatca
     1141 caagttaatg agtcttttga gaaaacatat taccctcaaa aagggaaata caatattatt
     1201 gaagtagctc ctggaaaaat cagggtaaaa gaagataata gtcctgatca aattgctgtt
     1261 cgtacaggct ggattagtag accaggggaa atgagtatat gtctgcctca taaattgatt
     1321 gttgaaattt taggagtaga ggagaatcct ttaatttatt agtatgaact aataagtacc
     1381 acgaatccta ttatagagac atggacggag taatctaagg aaagaccgtt aactaaaatc
     1441 gctaaaacct gtttacatta ttcttcattt aaggtggtta cggaattttg catatagaaa
     1501 gccatattag agctaacgag tttataaaat attaataggg atggtaggtg tcattacagt
     1561 ggataatact tatttaacag atgtgtttaa tcaatataaa ttacgcgaaa atttactgta
     1621 tcaaacttgg tttatcaaaa gtgaaaaacg tttgaaagcg tttaaaaaag ttaggaaata
     1681 cgtacaagta cttatcaaac atgtcaataa cggaacgttc ccaacagatt ttaaaaattc
     1741 agccctagag gacataatga atgtaattgc agaacaaaca gaaattttta aaggagccaa
     1801 gcatgcattt atgtggaaac ctaaattgag aattccggat atttatgaaa atagggaaaa
     1861 tcagttagct ttttcacttt gtcttgatca aattcttaaa gctaatcaag aaattaaaat
     1921 gttatttgct gtaaatattc tagcagaaaa gaaaatcaga gggcttggtc cagctgtcgc
     1981 aaacatttta tattttctag aacctaccat tttccctcct tttaacacag ctattgtaaa
     2041 tggatataat tatcttacgg gctcgaaaat tcgcttaggt aaatgggagg actattttaa
     2101 actccgtgat ggtatgattg aactcaactg cttaggagga cttttttcga aagatttggg
     2161 tgctatctca gcttttttat ttgatattgg gaaactaaat tatattgttc gcgaaaatga
     2221 agaagagtat gtcagaattt cagaaagtaa cacccagaaa ttaataaaac agaagttgga
     2281 aaaagaggat ggcaaaaatg tgcaccaaaa aatccaatat atcttagcta ctttaggtaa
     2341 tgagataggt tatcatgctt ggattgcctc aaacgatcat aatagaattg tagatgggaa
     2401 tcgcttagga gatgtgtcta tacctctatt accagaaaca atctatcaat taccaaatcc
     2461 gttaagtagg acgattggtt tgattgatgt tatttggttt tcaaaaaatg gggaaccgat
     2521 atgtgctttt gaggttgaaa aatcgacgtc aataatttct gggatgaatc gaatggatga
     2581 tttgtattcg attcatcaag aaaatttgat gatgtatatt gtctcaccgg atcaacgtga
     2641 agaggagata cgagcacaat ttaatagacc acattatatg cgtaatcaaa atttgcatga
     2701 tcacttacga tacattctat ttacagattt agagaaacat gctaatttta tgaagaaatt
     2761 tggcaaagat tttacaattt tagccccgat atctcattat ccaagtggtg aactagttcg
     2821 gtagttattc tggacaaaga agttgaaatt aatacggtta attgtagtat aaataagcat
     2881 ttgggcagaa ttggaaatca atcttccctt tttttacgag tagcttccac atttataatg
     2941 gcgctcattg ctattgaatg tcttagcaac gtccagaaga aaatcatcat attaatgctg
     3001 cccatgcttc cattttagta acttttcgtt gaagaaaatt gcggatagag tgaatactat
     3061 ctattcataa cctagaaatg ttatctaaaa aggtattttc cttatattca tcgaagataa
     3121 tggttctatt tgcacttaaa aaagaaacaa taaatcttac ttctagaatc ccctggtgta
     3181 tggactaccc tatacaccag gggatgttat gtactcttgg tggaatgcaa cgagtggatg
     3241 gaatgatgag gatcattttc tttggtgtca gaaatacata aagaaagatt ataaaccacg
     3301 catgccttat tcgttttata aagagtaaag ttagactaaa tattttgaga gaatcaattc
     3361 tattctgaac catgaattta gtgaatttta aagggactgt gacataagtc catagaagaa
     3421 aaccgcaaga aatgacgaga aagcgttcat ttcttgcggt tttttgggta aaataaaaag
     3481 gagcaccggt tcccgccaat gcaccatcat ttaatcctga aaggactaaa caaaatgtat
     3541 actaattata acatgaatca actcactttg gatctatcta cttcattttc tccaaaagaa
     3601 aatcatgtcg ccgtttttat ccatgaactg gtcgaagcgc ttcagattaa tgacccctat
     3661 ctttttggtc gaccaagaga atatgattta ggtgccatga tgaaggtggt tctttttgcg
     3721 tatacgcgag aaacctttac aagtcgcaag attgaacgct tagctgaaga aaacctatat
     3781 gctcgctggt tgacgcaaga acgggttccg acttatcgaa ctatcgcccg tttttgtgta
     3841 tccaacgatg tacaggagtt gaccaataaa ggtttagatc agttgacaga gtatctgcgt
     3901 gcacggaatc tgattgatga tgcgttgttt attgacggga ccaaaatctt ggcggatgcg
     3961 aataaataca gctttgtctg gaagaaaaat acgatccggt tcgatcaaat gaatcgcgaa
     4021 aaattgctta ctatgatgac ggaactaaaa gaagcatatg ccctgaaaca gattcccgaa
     4081 gggacgacct tgaccgtaga catgatagat gaactgttaa cacggatgga actgcgtctg
     4141 gatgaactag aaaatgaagt tgaggcaacg aaacgtcttt cgccaaatcc agcgaaacaa
     4201 caacggcgaa cgttgaaaag ccaagtacgc aaactaaatg caaagtgaga aaaacttctg
     4261 gaacatcaaa cgcagttttc tatttatggg actagaaaca gttattcaaa aaccgatcat
     4321 gatgcgacat ttatgcgcgt aaaagaagac cacatgaaaa atgtccaact taaacctgcg
     4381 tataacctgc agatcgctac atgtaatcaa tttgtgctcg gctacgatgt ctttcaaaac
     4441 ccaacagaca ctaaaacact gaaaccatta ctggaaaaaa tgaagactgc acaaaagtcc
     4501 cctcattatt tggtcgccga tgcaggttat ggttcagaaa gcaattaccg ctatatagaa
     4561 gatgaacttc ctcagcatac tgcactgatt ccttatggaa cgatgtttaa agaacaaagt
     4621 aagaaatggc agacagatga ccggaaagta atgaattggg tttacgagcc caatgaggac
     4681 ttttacatcg accccaaagg ggtacgattc aattttcatg cctaccgtca acgaacagat
     4741 gcggatggct ttgtccgaga ttttaaagaa taccaagcag aaaaaacgga tgcgaaccaa
     4801 gcgctcattc ctgaagcctt aaccccaaag gggaatcgta gaaagatcac tgtaaatccg
     4861 tcttgggagt atcataaaga aaaacaaaaa gaacggttat caacgcctga cattcaaaaa
     4921 atatatgggc ggagaaaagt cgacgtggaa acagtcttca gatttatgca ggcttgttcg
     4981 ggcttcactc gctacacggt tcgaggctta gagaaagtca gaaaacagac gggtttactc
     5041 attacggcaa tcaatatgat gaaattgaca aaaataggaa cttgaactac tcaaaatgaa
     5101 taaaaaaaca agaagcactc gaaaaatctc atgatttcca agtgctcctt gttttttgga
     5161 gagcgtaact aggtaactta tgtcacgcct cctttaactt attttaacct tgacttcaaa
     5221 tcgcttagtt cactacttaa gatatcattt tgctctttta aattttcaag atcctgtttc
     5281 aattgttcgt catctttttc attatgcgat cctgagtgca tacccctcat cataaatatc
     5341 atcattatcg gacataataa aagtaataac cactgcattg tcatcgctcc ttaactaagt
     5401 tctttagagt agcaacttct tcttttaatt gctcagtttg gatttttaaa cttgctatat
     5461 cattttcgga accagtgtgt tttgaatgat cttctccatg catatgatga tgcccagcat
     5521 gtccgtgccc tttatgcata aacatcattg agatagggca aattagtagt aatagtagtg
     5581 gtaagagatt aagtaatgct tccatgtaaa tcttcctcct tagatttttt
//
LOCUS       DAXQKX010000108         5522 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.111, whole genome shotgun sequence.
ACCESSION   DAXQKX010000108 DAXQKX010000000
VERSION     DAXQKX010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5522)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5522)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5522
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.111"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            133..1107
                     /locus_tag="ACF3MF_002707"
     CDS             133..1107
                     /locus_tag="ACF3MF_002707"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFE3928604.1"
                     /translation="MRQLHKEQIETAMAALKEKTIDHVYFTACGGSQAVLMAGQYLFD
                     KELTVPCHVYTANEFNYAIPKGLSENSLVITCSHSGTTPETVEATKKAREFGAMTICL
                     SNEEGSPLWEAAEYPVHYDWGKDVDASDLNKGILYGLLFNILLVLDGSKKWETCLNEF
                     DKLNDLVIAEKSKFEITAKEWGKNQKRDKIIYTIGSGINYGEIYSTAACWFMEMQWIN
                     SNAIHSGEFFHGPFEITDYDVPFILVKSIGDTRFLDQRVEDFTKKFSNKLMVLDQADF
                     DLESIDSVAKEYIAAVLSGVVIRQMVEAIAFERGHSLDVRRYMWQMKY"
     gene            1089..1550
                     /locus_tag="ACF3MF_002708"
     CDS             1089..1550
                     /locus_tag="ACF3MF_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFE3928605.1"
                     /translation="MANEILINRRLQKMANQLFHIVITTHSTLCEGYLKATKLILMND
                     ATGISAVPFKENTSPDDFEESMKEIISQHHLQPLIILTDLIGGTPNNVSIKQLNNNRI
                     QIIAGINLPLLLELLMAQSAGKSIEEIDFKELLNNSQKSMVHINSLLKDVS"
     gene            1600..2064
                     /locus_tag="ACF3MF_002709"
     CDS             1600..2064
                     /locus_tag="ACF3MF_002709"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFE3928606.1"
                     /translation="MIKLVRVDHRLLHGQVIFSWTKQYDINHIIVADNKVPGDPMSVM
                     ALTIAKPADCKLDIVKISDVKGIMETSPNDNYMILIKGPKEAFELVQNLPEIKEINFG
                     GVSKKSESKQYGKAVFLTPEELEATKKILDQEVKIFVQQVPSSSIENVDFSK"
     gene            2078..2827
                     /locus_tag="ACF3MF_002710"
     CDS             2078..2827
                     /locus_tag="ACF3MF_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFE3928607.1"
                     /translation="MLLKAILLGLVGVVAVIDSRLIGRQNIGRPLILSTLAGLVLGDL
                     HTGIVLGASLELISMGFVSIGAAGPPNMQLGSIIATAFAILTNSSTETALTIAIPVAV
                     AGEFMSIIMRMIIAQFGHAADKAIENNKFRKAQIIHIYWSFIFNAFVYFIPIFLTVYF
                     GADVVADLVDKIPEMITDALTVSGNMLSALGFAMLLSTMLSKKLYPYFIFGFFIVAYS
                     GLSLIGVTIFAALIAFVMHQVKYGKREEAHG"
     gene            2827..3657
                     /locus_tag="ACF3MF_002711"
     CDS             2827..3657
                     /locus_tag="ACF3MF_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFE3928608.1"
                     /translation="MENSTEKKRLITKKDLHKMCLRSWTIMCSWNYERQMHMGFMYGM
                     APILNKVYKNDEEKKREAYTRHMAFFNCTPQMTPFIMGLCASMEEQNAQAEEGNFNTE
                     SISMIKTSLMGPFAGIGDSFFQGTLRIITFGIGLSFAKQGSILGPILAVGLFAIPSIL
                     AVFYGGKLGYESGNKYLTKLYQEGLMDRVMQFASIIGLAVVGGMVASMVPIVTPLKFT
                     TGGTELVLQDLLDSIIPGLLPLVCTLGIYKLIKKNVSTNMLLLGCILAGFVLSIIGIL
                     "
     gene            3657..4304
                     /locus_tag="ACF3MF_002712"
     CDS             3657..4304
                     /locus_tag="ACF3MF_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFE3928609.1"
                     /translation="MIKALIFDMDGVLIDSEIMYQKWVFNFLKQENLSYPLYSYQKKI
                     GTTASIFDDIEKYNEGCNSLELKGKFTKYWKSQKIDYLDIFPNILIEQLEWLKKKKIK
                     MAIASSSPMDTINEVVTTCKIESYFDCLISGRDLPESKPNPTIFLKASEQLRIPVEEC
                     LVIEDSYNGIKAGKRANMKVLAIKDKRFSQDVSLADDVIYDIKYLRQEVQVKFGI"
     gene            complement(4402..5178)
                     /locus_tag="ACF3MF_002713"
     CDS             complement(4402..5178)
                     /locus_tag="ACF3MF_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFE3928610.1"
                     /translation="MNFQDNRPLYLQVEASIRNDIREKKYLPGEQLPTEEELCKIYGV
                     SKITIRKAFKLLTESGTVERLRGKGTFVTQKKESLKLAGVHGFSDSLSTRGHKIRYTV
                     LHSKIIKADEFLANKLQINVTDRVYNIKRLMWEDGAPMGIDNFFASEEKFPTLFEKGS
                     QYTSLYKLLEDDYDVKATSSIMEINGLSATPELSDLLQCIVGDPLFILEKVGKDKNNQ
                     PFHYSQSTVRCDRISYVIEVTENITLDTVHKNDSDPKVID"
     gene            5260..5403
                     /locus_tag="ACF3MF_002714"
                     /pseudo
     CDS             5260..5403
                     /locus_tag="ACF3MF_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608918.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="R3H domain-containing nucleic acid-binding
                     protein"
BASE COUNT         1889 a          748 c          984 g         1901 t
ORIGIN      
        1 attttattat ataaaattgt tataaaaaat tttttttgaa aaatagtatt gcaaaataaa
       61 gcaatttcat agataatagg tatcgtaaag ttatataact ttataatacc tattagagtg
      121 agggataaag aaatgagaca actacacaaa gaacagattg aaacagcaat ggcagcgtta
      181 aaggaaaaga caattgatca tgtatatttt acagcatgtg ggggttcaca agccgtttta
      241 atggctggtc aatatctatt tgataaagaa ttaactgtac cttgtcatgt ttatactgct
      301 aacgaattta actatgctat accaaaagga ttatctgaaa attctttagt tatcacttgt
      361 tcccattctg gcacaacacc agaaactgta gaagcaacaa aaaaagcaag agaatttgga
      421 gcaatgacta tttgtttatc taatgaagaa ggatctcctc tatgggaagc agctgaatat
      481 cctgttcact atgattgggg taaagatgtt gatgctagtg atttaaataa aggaattctt
      541 tatggtttat tatttaatat tttacttgtt ttagatggct ctaaaaaatg ggaaacttgc
      601 ttgaatgaat ttgataagtt aaatgatctt gttattgctg aaaagagcaa atttgaaata
      661 actgctaaag aatggggtaa aaaccaaaaa cgagataaaa ttatttacac aattggtagc
      721 ggtattaatt acggagaaat ttactccaca gcagcttgct ggttcatgga aatgcaatgg
      781 attaattcta atgctattca ttctggggaa tttttccatg gtccttttga aatcactgat
      841 tatgatgtac cattcatctt agtgaaaagt attggagata caagattttt agatcaacgg
      901 gtagaagact tcactaaaaa attcagtaat aaattaatgg ttttagacca agctgatttt
      961 gacttagaat ctatagatag tgtagcgaaa gaatatattg cagctgtact tagtggcgtt
     1021 gttattcgcc aaatggtaga agcgattgct tttgaaagag gccattcctt agatgttaga
     1081 cgctatatgt ggcaaatgaa atattaatta ataggaggtt gcaaaagatg gcaaatcaat
     1141 tatttcacat tgtgattaca acacattcta ccctttgtga gggttattta aaggcaacaa
     1201 aattaatttt aatgaatgac gccacaggta ttagtgctgt tccatttaaa gaaaatacta
     1261 gtccagatga ttttgaggag agtatgaaag aaataattag tcagcatcat ttgcaacctc
     1321 taattatttt aacggattta attggaggaa cacctaataa tgtttctatt aaacagttga
     1381 acaacaatag aattcaaatt attgctggga ttaatttacc tcttttactg gagttattaa
     1441 tggcccagtc agctggtaaa tctatagaag aaatagattt taaggaatta ctgaataact
     1501 ctcaaaaaag tatggttcat attaattcgc ttttaaaaga tgtcagttaa ggtggcaatt
     1561 tctattctat aaattttaaa aattgaagga ggaaatagaa tgattaaatt agtgcgtgta
     1621 gaccacagat tacttcatgg acaagtaata ttttcttgga ctaaacagta tgatattaac
     1681 catattattg tggctgataa caaagttcca ggagatccaa tgtctgtgat ggctttgaca
     1741 attgctaaac ctgctgattg caaattagac attgttaaaa ttagtgatgt taaagggatt
     1801 atggaaacat ccccaaatga taattacatg attttaatta aaggacctaa ggaagctttt
     1861 gaattagttc aaaatttacc agaaattaaa gaaattaatt ttggcggtgt gtctaagaaa
     1921 agcgagtcca aacaatatgg aaaggcagtc tttttaactc ctgaagaatt agaagccaca
     1981 aaaaaaattc ttgatcaaga agtgaaaata tttgtgcaac aagtcccatc ttcaagtatt
     2041 gaaaatgtag attttagtaa gtaagggggg aaaataaatg ttattaaaag ccattttatt
     2101 aggtttagtt ggtgtggtag ctgttattga ctccaggtta attggtcgac aaaatattgg
     2161 tagaccacta attttgagta cacttgccgg acttgtgcta ggtgacttgc atacagggat
     2221 tgttcttggg gcatctttag aattaatttc tatgggattc gtctcaattg gggcggctgg
     2281 acctcctaat atgcaacttg gtagtattat tgccactgct tttgcaattt taactaatag
     2341 tagtacagaa acagccttaa caatagctat cccagtggct gtagctggtg aatttatgag
     2401 tattatcatg cgtatgataa ttgctcaatt tggacatgct gcagataaag ccattgaaaa
     2461 taataaattt agaaaagctc aaattattca tatttattgg tcatttattt ttaatgcttt
     2521 tgtttacttt attccaatct ttttaacagt atattttggt gctgacgttg tggcagattt
     2581 agtagataaa attccagaaa tgattacaga cgccttgact gtctctggaa atatgctttc
     2641 cgcattaggg tttgcaatgc tattaagcac aatgttgagt aaaaaattat atccttactt
     2701 tatttttgga ttctttattg ttgcctattc aggtctttca ctaattggcg tgacaatttt
     2761 tgcagctctg attgcctttg taatgcatca agttaaatat ggaaaaagag aagaggcgca
     2821 tggttaatgg aaaatagtac agaaaaaaaa cgtttaatca caaaaaaaga tcttcataag
     2881 atgtgtcttc gttcatggac aatcatgtgt tcgtggaatt atgaaagaca aatgcatatg
     2941 ggatttatgt atgggatggc gccaatttta aataaagttt ataaaaatga tgaagagaaa
     3001 aaaagagaag cttatactcg tcatatggca ttttttaact gtacgcctca aatgactcca
     3061 tttattatgg gactttgtgc ttctatggaa gaacaaaatg ctcaagcaga agaaggaaac
     3121 tttaatactg aatctatctc catgattaaa accagtttaa tgggtccttt tgctggaatt
     3181 ggtgattcat ttttccaagg tactttaaga attattacat ttgggattgg attgtctttt
     3241 gctaagcaag gtagtatttt aggaccgatt ttagctgttg gcctttttgc tataccttct
     3301 attttagctg ttttttacgg cggtaaatta ggatatgagt ctggcaataa ataccttact
     3361 aaattgtatc aagaaggtct tatggatcga gtaatgcaat ttgcttctat cattggtttg
     3421 gctgtagtag gtggaatggt ggctagcatg gtgccaattg tcaccccttt aaaattcact
     3481 acagggggaa cagaacttgt tttacaagac ttacttgatt ccattattcc tggattatta
     3541 ccacttgtat gtactttggg aatatataaa ttgattaaga aaaatgttag tacaaatatg
     3601 ctcttattag gttgtatttt ggcagggttt gttttaagta taataggtat cttataatga
     3661 ttaaggctct aatttttgat atggacggag ttttaattga tagcgagatt atgtatcaaa
     3721 agtgggtatt taatttttta aaacaagaaa atttaagcta tcctttgtat tcttatcaaa
     3781 aaaagattgg aactacagca agtatttttg atgatataga aaagtacaat gagggatgta
     3841 acagtttaga attgaaggga aaatttacta aatattggaa atcgcaaaag attgattact
     3901 tggatatttt tcctaatata ctaattgaac agcttgaatg gttaaaaaag aaaaaaataa
     3961 aaatggcaat tgcttcttcc agtccaatgg atactataaa tgaagttgtt accacttgta
     4021 aaatagagtc atattttgat tgtttaatta gcggaagaga tttgccagaa agtaaaccta
     4081 atcctactat attccttaaa gcttcagaac agctcagaat tccagttgaa gaatgtctgg
     4141 tgatagaaga ttcttataat ggtataaaag ctggtaaaag agcaaatatg aaggttcttg
     4201 caattaaaga taaacgtttt tctcaagatg taagtctagc agatgatgtt atttacgata
     4261 ttaaatatct gcgacaagaa gtacaggtga aatttggaat ataaataagt tttttgatgt
     4321 atttagagaa tattagtaaa aataaaaatc atgcccaaat ctaatcaaaa ttgattgctt
     4381 tgggtatgat ttcttttaat atcaatctat tactttagga tctgaatcat ttttatgcac
     4441 cgtatctaaa gtgatatttt ctgtgacttc aataacataa ctaattctat cacaacgaac
     4501 tgtggattga gaataatgaa atggttgatt atttttatct ttgccaacct tttctaaaat
     4561 aaatagcgga tctcctacta tacattgcaa taagtcggaa agctcaggtg ttgcagataa
     4621 accgtttatt tccataatag agctcgtagc tttgacatca tagtcatctt ctagaagttt
     4681 atataatgaa gtatattggc tacctttttc aaataaagtt ggaaattttt cttctgatgc
     4741 gaaaaaatta tcaattccca tcggggcacc gtcttcccac attaaacgtt taatattgta
     4801 aactctatca gttacattga tttgtaattt attagctaaa aactcatcag cctttataat
     4861 tttagaatgt aaaacagtat atctaatttt atgtcctcgg gtagaaagag aatcgctaaa
     4921 tccatgaact ccagctaatt ttaaactttc ttttttttga gttacaaagg tccctttccc
     4981 ccttaatcgt tcaactgttc cactttctgt taaaagttta aaagcttttc gaatggtaat
     5041 cttacttact ccataaattt tacataattc ttcttctgta ggtaattgct ctcctggaag
     5101 atattttttt tcacgaatat cgttacgtat agaagcttct acttgtagat ataatggtct
     5161 attatcttga aaattcatag tacactccct aaaaagttat acttcattat atcacaattt
     5221 attaaaataa aagattaaga tataaatata aatgaactag tctttgacta accaatgccc
     5281 gcttttgaaa gaaaacaaat tcattctgtt ttaagtaaaa atccttatgt taccactcat
     5341 tctgaagggg atgagcctta tcgctacttg gttgtggaac caagcgataa gacaatttta
     5401 taaattcaat attaattaaa ataaaaacaa acaaagtaga ttattttact ttgtttgttt
     5461 ttttattggg agcgtcaata attttgtgta aataactcgt ccttctgcaa aataatgggt
     5521 ta
//
LOCUS       DAXQKX010000109         5088 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.112, whole genome shotgun sequence.
ACCESSION   DAXQKX010000109 DAXQKX010000000
VERSION     DAXQKX010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5088
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.112"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(47..871)
                     /gene="iolB"
                     /locus_tag="ACF3MF_002715"
     CDS             complement(47..871)
                     /gene="iolB"
                     /locus_tag="ACF3MF_002715"
                     /EC_number="5.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0019310 - inositol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-deoxy-glucuronate isomerase"
                     /protein_id="HFE3928611.1"
                     /translation="MEKTLKHQPLNKELAPGVKQIQNIRQSNSALSYIEFQILELEKG
                     ASYKETGSQQEVCIVILTGKIKVKAADTWYEDLGTRESVFEKIPTDSIYLPAEHSFEL
                     VATTDNVRLALCYSPAKKALPISVIRAEDNTVEERGLYQNKRLVHNILPDNVDTASSL
                     LVVEVYTEGGNFSSYPPHKHDQENLPHESFLEETYYHELDPEQGFVFQRVYTEDRSLD
                     ETMTVEHQNVVEVPKGYHPVGVPDGYTSYYLNVMAGPERIWKFHNEKKHEWILQRK"
     gene            complement(910..2826)
                     /gene="iolD"
                     /locus_tag="ACF3MF_002716"
     CDS             complement(910..2826)
                     /gene="iolD"
                     /locus_tag="ACF3MF_002716"
                     /EC_number="3.7.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002397168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016823 - hydrolase activity, acting on
                     acid carbon-carbon bonds, in ketonic substances [Evidence
                     IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019310 - inositol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3D-(3,5/4)-trihydroxycyclohexane-1,2-dione
                     acylhydrolase (decyclizing)"
                     /protein_id="HFE3928612.1"
                     /translation="MEKTVCLTTAQALLKFLNQQYISIDGKETPYVEGIFHVYGHGNV
                     LGIGQALELEPGHLKSYSGKNEQGMAHAATAFARQNLRKKIFAVSTSVGPGAANLLTA
                     AGTAFANNIPVLFLPADTFATRQPDPVLQQLEHASSVAFSTNDAFQAVSRYWDRINRP
                     EQLMSALLRAFEVMTNPATMGPATICLPQDVEAEAYAYPEEFFKKRVHYIDRRIPTAR
                     ELAEASQRIKASKRPVIIVGGGCKYSEAGEILEQISRDCQIPLVETHAGKSTVSWDFK
                     NNLGGMGILGTSAANKAVQQADLIIGIGTRYTDFTSASKSIFNFEQAKMMNINVSRQQ
                     AAKLEAFQVVGDAKATLEQLAPMIEGYQTAYGEKIDELKEEWISERNRLKAAHFKRKD
                     FTPEIKDHFSQEILNEYADALATNLTQTEVFIHLNDFVDEDAIVIGSAGSLPGDMQRL
                     WNPVKENTYHLEYGYSCMGYEIAGAMGVRMARPEQEVYALVGDGSFLMLHSELVSSLQ
                     YDKKINIVLFDNSGFGCINNLQMDNGGASQGTEFRNTKDEIMNIDYAKVAEGYGAKTY
                     RVSSIAELQAAVEDAKKQTRSTLIEIKVLPKTMTEGYDGSWWNVGISEVSGKAAMQEA
                     YKAKQAKLATIRKY"
     gene            complement(2837..3871)
                     /gene="iolC"
                     /locus_tag="ACF3MF_002717"
     CDS             complement(2837..3871)
                     /gene="iolC"
                     /locus_tag="ACF3MF_002717"
                     /EC_number="2.7.1.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047590 - 5-dehydro-2-deoxygluconokinase
                     activity [Evidence IEA];
                     GO_process: GO:0019310 - inositol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-2-deoxygluconokinase"
                     /protein_id="HFE3928613.1"
                     /translation="MSYIKFDQSKEFDLLLLGRVAIDFNPAYNDQVKEEFKPLKKVHM
                     FEKFVGGSPANIAVGVTKHGMKAGFIGTVSDDQFGEYVIDYFNEQGIDTSQISKAQHG
                     EKLGLTFTEMLSSKESNILMYRNQAADLQLSVEDIDEDYLKRSKALLISGTALAESPS
                     REAVIKAVMLAKRNNVKIIFDIDYRAYNWKNNDDISIYYSMIAKESDIIMGSREEFDL
                     TEKLIQPNMSDNESAAFWHSCGAEIVVIKHGMKGSTAYTADQQQFSIKPFPVEARKGF
                     GGGDGYGSGFLYGLFEGWEIIDCLEFGSAEASMMVKSNNCSDSLPTTQEVKDFITLEK
                     EIYGEMIARI"
     gene            complement(4028..5044)
                     /locus_tag="ACF3MF_002718"
     CDS             complement(4028..5044)
                     /locus_tag="ACF3MF_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016633586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFE3928614.1"
                     /translation="MAGTIKEIAEKAGVSRGTVDRALNDRGRINPEVAERIRAIAKEM
                     NYVPKKKKVIKETTLKLGIVTQLAKSSFMIPIRSGLESIIGDLKKRNIDCFLEEVDGV
                     DEAAQLQALDRLVELGVKGIAIMPVDSDGIREKINQLTDQGILIITFNSDILGTNRQC
                     FVGMDNFKSGKTAAGLLGMLTKGKGKVLAITGYFGNSVNSLRVAGFVEELKESFPELE
                     LTGVQSSFDSSAEVEKILSNTLENYSNLDGVVVFSGGQAGIARALEKIDESKRPFVII
                     YDLTKNNIEMLKNDQVDFLIDQDGFVQGYRSLLMLANQLQNNKTVTKDALFTDIIIKT
                     KYNI"
BASE COUNT         1337 a         1271 c          909 g         1571 t
ORIGIN      
        1 acctaactaa acctaactaa actttatgta tctaacagct taataactac ttgcgctgca
       61 agatccattc gtgtttcttt tcattgtgga atttccaaat tcgctcaggt cccgccatca
      121 catttaaata gtaggaagta tacccgtcag gtaccccaac tggatgatag cccttaggaa
      181 cttcgacgac attttgatgc tctaccgtca tcgtttcatc tagtgaacga tcttccgtgt
      241 agacccgctg gaaaacaaat ccctgctctg gatcaagctc atggtaataa gtttcctcta
      301 aaaaagactc atgtggcaga ttctcttgat cgtgcttatg aggaggatag ctggaaaaat
      361 taccgccctc ggtataaact tcgacgacca gcaggctgct ggcagtatcg acattatccg
      421 gtaaaatgtt gtgaacaagt cgtttattct gatagagtcc acgttcttcg acggtattat
      481 cctccgcgcg aatcacactt atcggcaaag cttttttcgc tggtgaatag caaagcgcca
      541 atcggacatt gtctgtagtt gccacaagtt caaacgaatg ctccgccgga agataaatac
      601 tgtcggttgg aattttttca aaaacagatt ctcgtgttcc taaatcttca taccaagtgt
      661 ctgctgcttt aaccttaatt tttccagtca aaatgacgat acagacctcc tgttgactgc
      721 cggtttcctt gtaagaagct cccttttcca gctccaaaat ctgaaattcg atataactca
      781 aagcagaatt agactgccga atattttgga tttgttttac tccaggtgcc agttctttgt
      841 ttaatggttg atgcttcaat gtcttttcca atcaatccac tccttatttt caatcacaaa
      901 aagcaatatt taatactttc tgatagtggc aagtttcgct tgtttggctt tgtaagcctc
      961 ctgcatggct gctttacccg atacctctga gataccgacg ttccaccagc tgccgtcgta
     1021 gccttctgtc atggttttag gaagtacctt tatctcaatc aacgtcgatc gcgtttgctt
     1081 cttcgcatcc tcgaccgctg cttgtaattc tgcaatcgag cttacacgat acgtttttgc
     1141 accatagcct tcagcaactt tggcgtaatc gatgttcatg atctcgtcct tggtatttct
     1201 gaattcggtt ccttggctag ctccgccatt atccatctgt aaattattga tacagccgaa
     1261 accagaatta tcgaaaagta caatgttgat ttttttatca tattgcaaac tagaaaccag
     1321 ctcgctatgc aacatcaaga aactgccatc gcctactaag gcatagacct cttgttctgg
     1381 tcgagccatt cttacgccca tcgcaccagc gatttcatag cccatacaag aataaccgta
     1441 ttccaaatga taggtattct ccttcacagg gttccataag cgctgcatat cccccggcaa
     1501 tgaaccggct gaaccgatca cgatcgcatc ctcatcaaca aaatcattta aatgaatgaa
     1561 gacctctgtt tgcgtcaaat tcgtagccaa cgcatcagca tattcattca agatttcttg
     1621 agaaaaatga tctttgattt ctggcgtaaa atctttacgc ttaaaatgcg cggcttttaa
     1681 ccgatttcgc tcactgatcc attcttcctt cagttcatcg atcttctcgc cataggcggt
     1741 ttggtaacct tcgatcattg gggcaagctg ctccaaggtc gctttcgcat caccaaccac
     1801 ttgaaaggct tccagcttag cggcctgttg tctgcttacg ttaatattca tcattttcgc
     1861 ttgttcaaaa ttaaaaatac ttttagaagc tgaggtaaaa tcagtgtagc gtgtgccgat
     1921 ccctatgatc agatccgctt gctgcacagc tttattagca gccgaagttc ccaaaatccc
     1981 cattccgccg agattgtttt taaaatccca cgaaacagtc gatttacctg cgtgcgtttc
     2041 aactagcgga atctgacaat ctcttgagat ttgctcaaga atctcaccag cctccgaata
     2101 tttgcagccg cctcctacga tgatgacagg tcgtttactg gcctttattc gttgactcgc
     2161 ttcagcaagc tcacgagcgg tcggaatcct gcgatcaata taatgtactc tttttttgaa
     2221 aaattcctcc ggataggcat aggcttctgc ctccacgtcc tgcggcaaac aaatcgttgc
     2281 cggacccatc gttgccgggt tcgtcatgac ttcaaaggcc cgcaataacg cggacatcaa
     2341 ctgctctggt cgattgatgc ggtcccagta gcgagaaacc gcttgaaatg catcatttgt
     2401 cgaaaaggct acactgcttg catgttccag ctgctgcaag accggatcag gctgacgtgt
     2461 agcaaacgta tccgccggta aaaaaagtac ggggatatta tttgcgaatg ccgtacccgc
     2521 tgctgttaac agattggccg cgcccggtcc aacagatgtt gatacggcaa aaattttctt
     2581 gcgtaaattc tgtctggcaa aggcagtagc cgcatgggcc attccctgct cattttttcc
     2641 gctataactt ttcaaatgtc cgggctctaa ttccagcgcc tgaccgatcc ccaaaacatt
     2701 tccgtgacca tagacatgaa agataccttc aacataaggc gtttctttgc cgtcgatgct
     2761 gatgtattgt tgattcaaaa attttagtaa tgcttgtgct gttgttaaac aaaccgtctt
     2821 ttccattttt ttcaccttaa atccgagcga tcatttcgcc gtatatttct ttctccaatg
     2881 taataaaatc ttttacctcc tgagtcgtcg gtaaagaatc tgaacagtta ttgcttttga
     2941 ccatcattga tgcttccgct gagccaaact ctaaacaatc gatgatctcc cagccttcga
     3001 ataaaccgta taagaaaccc gagccgtaac catctccgcc gccaaagcct ttgcgtgctt
     3061 ccaccggaaa cggcttgatt gaaaactgct gctgatcggc cgtataagca gtcgatcctt
     3121 tcattccatg tttgattacg acaatctcag caccacaact gtgccaaaaa gcagcgcttt
     3181 cattatctga catgttaggc tggatcaact tctcagttag atcgaactct tctcttgaac
     3241 ccatgataat gtctgattcc ttagcaatca tcgaatagta aattgaaata tcatcgttgt
     3301 tcttccagtt ataagcacgg taatcaatat caaaaataat tttgacatta ttccttttcg
     3361 ccagcatcac tgccttgatt acggcttctc tggacgggct ctctgctagt gcagttcctg
     3421 agattaatag tgcttttgac cgtttcaagt agtcctcatc aatatcctca acgctaagct
     3481 gcaggtctgc ggcttgattt cgatacatca aaatattact ttcctttgat gagagcattt
     3541 cggtaaaagt cagccccagc ttttcaccat gctgcgcttt gctgatctga gacgtatcga
     3601 tgccttgttc attgaaataa tcgatcacat attcgccaaa ctgatcgtcc gagactgttc
     3661 cgataaaacc agctttcatg ccatgtttag taacacccac agcaatattg gcaggagatc
     3721 cgcccacaaa tttttcaaac atatggacct ttttcaatgg tttaaactct tctttgactt
     3781 gatcattgta ggcaggatta aaatcaatag cgactcttcc taaaagcagc aagtcaaatt
     3841 cttttgattg gtcaaacttt atataactca atatatccac ctctttatcc gttcttctat
     3901 ttctgaggca agtatagcac gccaaaacaa agcgtgcaat atttatttta gaacgcaata
     3961 ttgcgtgctg tttgaaaatg acggcaaaaa aaacgtgaat cgccttacat cacgattcac
     4021 gcctagatta aatattgtat tttgtcttaa taattatatc agtaaatagc gcatcttttg
     4081 taaccgtttt attattttgc agctgattcg ctaacatcag taatgaacga tagccttgaa
     4141 caaatccatc ttgatcgatt agaaaatcaa cctgatcgtt tttcagcatc tcgatattgt
     4201 tcttagtcaa atcataaatg attacaaagg gccgcttgct ttcatcgatt ttttccaacg
     4261 ctcgggcaat tcccgcttgt ccgccagaaa agacgactac gccatctaag tttgaataat
     4321 tctccaaggt gttgcttaaa atcttttcaa cctcagcact cgaatcaaag ctgctctgaa
     4381 cacccgtcag ctccagttca ggaaacgact ctttcaattc ttcaacaaag cctgccaccc
     4441 gtaagctgtt gacgctattt ccaaagtagc cggtaatcgc tagaaccttg ccctttcctt
     4501 ttgtcagcat acctaacaat cccgcagccg tttttccgct tttgaagttg tccatcccaa
     4561 caaaacactg tcgattcgta ccaagaatat ccgaattaaa ggtaatgatg aggatgcctt
     4621 gatcggtcaa ttgattaatt ttttctctga taccatcact atctactggc atgatcgcga
     4681 tcccttttac tccaagctcc accaatcgat ccaacgcctg cagctgggcc gcttcatcga
     4741 ccccgtctac ctcttctaaa aaacaatcaa tgtttcgctt ttttaaatcc ccgataatag
     4801 attccagacc tgatcggatc ggaatcataa aagaagattt cgccaattga gtgacaatcc
     4861 ccagcttgag cgttgtctct tttatgacct tctttttctt tggaacatag ttcatttcct
     4921 tggcgattgc tctgattctt tctgcaacct caggattgat ccttcctcga tcgttcaatg
     4981 cccgatccac tgtccccctt gacactcctg ctttctcagc tatttcttta attgtacccg
     5041 ccatcttgcc tctccttttt tcctattgtg tttattttat cacaaaac
//
LOCUS       DAXQKX010000110         4961 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.115, whole genome shotgun sequence.
ACCESSION   DAXQKX010000110 DAXQKX010000000
VERSION     DAXQKX010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4961
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.115"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..135
                     /locus_tag="ACF3MF_002719"
     CDS             <1..135
                     /locus_tag="ACF3MF_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFE3928615.1"
                     /translation="FNQVNQGFISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA
                     "
     gene            complement(243..1328)
                     /gene="xerS"
                     /locus_tag="ACF3MF_002720"
     CDS             complement(243..1328)
                     /gene="xerS"
                     /locus_tag="ACF3MF_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HFE3928616.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
     gene            1677..1872
                     /locus_tag="ACF3MF_002721"
                     /pseudo
     CDS             1677..1872
                     /locus_tag="ACF3MF_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
     gene            complement(3404..3922)
                     /locus_tag="ACF3MF_002722"
     CDS             complement(3404..3922)
                     /locus_tag="ACF3MF_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HFE3928617.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
     gene            4289..4537
                     /locus_tag="ACF3MF_002723"
     CDS             4289..4537
                     /locus_tag="ACF3MF_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928618.1"
                     /translation="MVKLKMLYIGLQHRSFFDCALGKKYYEVKIDDDTFLTAHQMKQL
                     QKRNDQLEENLILKKRLPYSRLARRTIKGQDLPEDHPF"
BASE COUNT         1637 a          816 c          748 g         1760 t
ORIGIN      
        1 ttcaaccaag tcaatcaagg attcatctca tccgttgcgt ccaaaagaaa ccatatccct
       61 agaaaatcac taaattacca aacaccatta gaagtttttt tgagttacgt aaatggaaag
      121 ttttgtctcg cttaatttga caaataatat aatataaaaa tgataatgaa gcttgccttt
      181 aaagttgggc ttttatctaa ttttagagac aggcttcatt attatactat tttttactac
      241 atttacaaag cgttcaaagc atcaattgta gctgcattgt ctatatgagt atataaagtt
      301 gttgtatttg tacttgtatg tcccaattgt tgggcagtta ataccaatga atttgtctgt
      361 tgatagagtc tagtagccaa agtatgacgt aatttatgtg gactgacttg gactctgaat
      421 ccttttgaat attttgctac catccgttcg attgcaatac cggatatacg cttggcttct
      481 ccttgataaa ttgctagaaa taaagctttt tcgttttctg ttactttgta tcgttctttc
      541 cgaatagcta gataattagc taaatattcc attgcaaatg ctgctatatt tactgcgtct
      601 ctcttatttc cttttctagt tactaccaca ttattctttt ctaaagatag gtcctctaaa
      661 ttaatattta caacctcgga gagtcttaat ccagatccta aaatcaatgc attgatcgcc
      721 aggtctcttt ctacatctcg ttgataatag atcaaagctc gtttgctcaa agttttttta
      781 tattcattgg caatataatc tagataattt tgtgtatctt cgtctagaaa taattttttc
      841 tcgattgcgt ttgcacgggc agctaacgta gttttatctg tgatagttgc tacttgatcc
      901 ataggattat tttctaagta tggttttcct aaaggattat tggaactttt cgaaagatat
      961 ttaaatagaa cctttaatgc tgtgatattt ctattgatag tagaagtaga tagacctaag
     1021 ttattattat ctttgagctt agtttttgtt gtctcttttt ttacattttc ctttgtgcga
     1081 cgtttcaaat gagatttgta caagtttaga tcataggcag ttaactgtct tatcgaggtg
     1141 attgaagtat cgggaacgat agactcactc agaagccatt cataaaagag cttataattt
     1201 tttagatatt ctaaagtagt tcgaggtgat tgatctttat cctcacgatc ttgaacaaaa
     1261 tcttttatat aatcgggcat atgaagtatg attgtatcta ttttttgata tatttctgta
     1321 tttttcatgt tattcatcct ttcgataagt aggggagagg agtatctcta taattggact
     1381 ataccaatta tagagtgttt tgtcaattgg tatactctga aatttattaa tttatttcaa
     1441 aaaagcagat aaataggtat agatttaata atttaaaata aatggtatac atgaatagga
     1501 aaggaaacag aaggaggcaa tcttaatttt ttaaattgtc taaattatat agaaagaaca
     1561 atctttctat ataattagac ataagagaga ctacggttga tttgatatta acaagcgtat
     1621 atgaatgtat atacaaataa aaaaggggag ggagaagtta aagaaaattc agagaagtgg
     1681 ggcactcagt agtattaaca atttaaaagg aatttcttaa agaaaatggg ttgcatcctg
     1741 gagatacaat ttttttagat aaagaaaaaa ttcaagcaac aattcaaaaa aatcttaact
     1801 gctgagattg atgtagcaat atctcaatca tcaacaaagt acgatcctgc ctttcaaaag
     1861 cttattgata aatgtttatt cattataaaa ataaaagaaa aatttatgtc agcttttttc
     1921 atcaaagtgg taatgataat tcgtctatta attgtatttt ttaggaaata tggtataatt
     1981 gttttaacga aaaggtaatt catgatacac caaaaaccac tagctggcgg gctagtggtt
     2041 ttcttttacg ttctattcag attaacgggt aggcttactg tcttttttgg caataatttt
     2101 gcaatcaagc catttacaga tgtaatgcgc ggatacttct gctaagattg caaaaaacat
     2161 atcgaaaagg taattcataa tacaacctcc tccccttgcc ataataggcc ggggtagcag
     2221 acagcataaa tattatacca taactgaaaa tttcatttta gtacatttca atatattgat
     2281 gaaccagcac aataaaacat gccatgacta acagaaaaaa acttattaaa ccagatataa
     2341 cttgtaaaca tccaactata tagaaaacgt aaattttcta tatagttgga ttaagataac
     2401 gactatttat tttatcatat ttttactata ccctatactt ttacttggta tatttatgaa
     2461 taatcgcaaa tttaccccta tactactagt ttgtaagtta gattaataaa aatactaaag
     2521 ttatttgttc ttttattaaa tacacctaca acttataaat tgatggtatt tagataacac
     2581 gaaagaataa aaataacagc tgatagtaaa gtttgttgac gattgctact caatcgaaag
     2641 tgagttagtg cgtatgaact tgcttctgaa aacttatgaa atgaaagacc ttttacatct
     2701 tgcagaaatc gttactggga ttaaactaag caataaaaac taatgttccc ctcattcttt
     2761 gaacttctac tatttgattt atttattctg ataaatgacg atttcacctt caggatcttc
     2821 aaatcccgta tagaatttat ttaagatctc ttcagtatca gtaataggat aggcgatagg
     2881 ccacataccc tttgatggtt agaataaact gctcaaaatc tgtatcgtat gttggcttta
     2941 gcatattaac aaaggctatc tccaaattat aaaccataag cgttgaatcg ttcttaacaa
     3001 tttcaattct tcctaaccca aagtcagaag atataattac cggacttgcc ttacccttca
     3061 tgtgggttgt tgagattcca tatttaaagg gaattgtcgg tactatcggc ggtctgaaaa
     3121 acatcccaaa aataaaaaaa tctttcccct gctagtctcc taagtccctt tgtagcggat
     3181 atggcaccat aatctcattt tatcgaagtg agtcatggtt tatctgttgg ccaaccaaaa
     3241 ttgatacaat ctaacgatgc accctctacg gcattctagg ggagtgcact tgcattcacc
     3301 caataaaaac cggcagttag caaagaactt atgtagtcgt atgttcttac tgttaacata
     3361 caagaggtct cctttccaca attgcttagc agtaaacggg aatttacaaa gctaatctct
     3421 tccattttct tatctttgtt ctaaaagtcc caaatggagc aactgtattt acatgaataa
     3481 atttatatac ttcccataca gccgttttgg ttgcctcgtc tgcccatttt cttttgtgtg
     3541 cagtgaatag atcttcatca ctcattgaat caatcatcat gttaatatca tcaatattac
     3601 gattgagaat ttcctctaat tctttcaatg gtagatgtgc ataggtattt gtaaaccact
     3661 tatataactc tcctaactga ttccatttaa attgatcaga aggcgtttta acagataatc
     3721 catttctttc atcattttcc cattttagaa ttaaattcgt ccaaccaact tgatatgcta
     3781 aattttcagc aggtgttcta tccacttcct caactctttt atccttcaat tcttcaggaa
     3841 tagtttcaaa ttctaaaata tatttagtat aagtcctatt tatttctttt tttaattctt
     3901 ctttattttt atatgttctc attatattac ctccataaat tcctaattgt ctcctttaat
     3961 tcatctataa tttcatccac gatattttaa tccgttctac aatgcatatc tgatatgcat
     4021 tgactgtcta actcatatgt gaatgattta taaaatatcc caacgtctca tctaaagaaa
     4081 tgttgatcgt cagcaaggag ctaaaaaata cgaatatatt tcttttgtag taaaatcgga
     4141 ctggtttgca tatcattttc ttcgtaaata tcaaaatcat gttaactact atcaattact
     4201 aataaaaact accactttaa gcgttaagaa ctgttaagtt tagttaagtg aggatagttc
     4261 acaaaatcca ttgttaaact tcacgaaagt ggtaaaactc aaaatgcttt atataggatt
     4321 acagcatcgc tctttcttcg attgcgcgtt gggtaaaaaa tattatgaag taaaaattga
     4381 cgatgacacg ttccttacgg ctcatcagat gaaacagcta caaaaacgaa atgatcaact
     4441 cgaagaaaat ttaattctaa aaaagcgatt gccatattca cgcctcgctc gacgaactat
     4501 taaaggtcaa gatttacctg aagatcatcc tttttaggaa attgaagctt tttatgttgc
     4561 acaatgcatt tataatacta caatgatgtt ttcaccagat attcttctag ggtgcggtgt
     4621 aatgaaacag atacacttgc aaaagaaaat tcaccgcgaa tttactaaaa ttatgaataa
     4681 ttatgttaat cttccgaaat ttttttccaa aattaaggga tcaagctggt gttatagatt
     4741 gtttaaggtt ggcaaaaaaa taacttcttt ttaaacaatt atagaaaacc gatactctgt
     4801 taagttggtt gacacggtgt cgatttttat gactttctta ttctgaaact tcactaacgg
     4861 acagtaccta aaaagtctat agtatggacg tttacgagta ctattttatc aaaaatgctg
     4921 ctcatttcaa cttatatgtt ttagtgaact acccccactt a
//
LOCUS       DAXQKX010000111         4933 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.116, whole genome shotgun sequence.
ACCESSION   DAXQKX010000111 DAXQKX010000000
VERSION     DAXQKX010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4933
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.116"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            85..972
                     /locus_tag="ACF3MF_002724"
     CDS             85..972
                     /locus_tag="ACF3MF_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFE3928619.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1112..2038
                     /gene="cysK"
                     /locus_tag="ACF3MF_002725"
     CDS             1112..2038
                     /gene="cysK"
                     /locus_tag="ACF3MF_002725"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HFE3928620.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2274..2720
                     /locus_tag="ACF3MF_002726"
     CDS             2274..2720
                     /locus_tag="ACF3MF_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFE3928621.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2993..4345
                     /locus_tag="ACF3MF_002727"
     CDS             2993..4345
                     /locus_tag="ACF3MF_002727"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HFE3928622.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4516..4803
                     /locus_tag="ACF3MF_002728"
     CDS             4516..4803
                     /locus_tag="ACF3MF_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFE3928623.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT         1695 a          813 c         1030 g         1395 t
ORIGIN      
        1 aattaaaagt ataatttaat taattaagtt tgttttaaga agagaacttt ttattaagtt
       61 tttttatttt gaggaggaat ttgaatgcaa gagctgaaga cccgcagtgc ccggcaccat
      121 agacctaaaa gaaaaatggt gatcaataaa aaagcgattg ctcctttaat tggaacgagt
      181 cttttagttg ggccgatgat ggttacagcg gtaccgcaac atgttcatgc agatgaacaa
      241 ggatctcaaa cagtcgctga tcctcaagcg tttatcgatc aaatcggctg gtctgcgtca
      301 gaagttgctg caagtaatga cttgtatgct tcagtcatga tcgctcaagc gttgttggaa
      361 agtgcatatg gcacttccgg attagctagt gcgccaaatt ataatctatt cggtgtgaaa
      421 ggaagctata acggacaggt cgtttatatg gcaaccaaag aatatgtaaa cggacaatgg
      481 gtaacgatga atgagccatt ccgaaaatat tcttcttatt gggaatcctt ccaagaccat
      541 gcgaatgttc ttcgttcaac cagtttttcc acgggcgatt atcattatgc tggcgtgtgg
      601 aaaagcaata caacaagttt ttatgatgca acagcgtact tgacaggtcg ttatgctacc
      661 gatccaaatt atggggccaa attgaactca ttgattaata cttataattt aacccgtttt
      721 gatacgccat caacaggttc ggctacaaca accacaagta caacaacaac gactactacg
      781 acgacttcaa cgtcatcatc ttcaacaaca gatgtaaata caaataatgg tcagacatat
      841 acagtcgtgt caggtgatac gctatgggat attgcacaaa aatttggcat gtctgttgat
      901 gatctaatgg cgaaaaatgg catgtctatg tccagttatt ctttattagt tggtcaagaa
      961 ctaaacgttt gatttagata aaaaggcaaa gaaattacca tatatggtat atctttgtct
     1021 tttttttgct agtcaaagac gaatcactcg ccataaatga acagattgta ttatgataag
     1081 taagaagagc aaagacaagg aggaattgaa gatgacagct atctataact cagtcaccga
     1141 attgattggc aaaacgccaa tcgtcaaatt aaataaaatc gtaccagaag attcagcaga
     1201 tgtttttgta aagcttgagt tttttaatcc aggaggaagt gtaaaagatc gtattgcttt
     1261 aagtatgata gaaaaagcag aacacgatgg tctactgaaa ccaggtgata ctatcattga
     1321 acctacttct ggaaatacag gaatcggatt gtcgatggta ggagttgcaa aaggatataa
     1381 agtaatcatc gtgatgcctg agacgatgag tatcgaaaga cgtttattga tgaaagggta
     1441 cggcgcagag ttgattttga ctcctggtgc ggatggtatt tctggatcaa tcagagaagc
     1501 agaacgtttg gcaaaagaaa acggctactt tttaccatta caatttgaaa atgaagcaaa
     1561 tcctcttgtg catgagaaga cgactggtcc tgagatacat caagcatttg gagtaaatgg
     1621 cttggacgcg tttgttgcag gtatcggtac aggaggaacg atcactggcg ctggccgaga
     1681 attaaaacgt gtgtatccga aaatcgaatt aatcggggta gaaccagcag aatctgctat
     1741 tttagaaggg aaagaagcgg gacctcacaa aatccaagga atcggtacag gttttgttcc
     1801 taaaacactg gatacttctg tgtatgataa agtcctttct attagtggag acgaagcgat
     1861 ggaaacagct agagaagttg ggcgaaaaga agggatttta gtaggcatct catctggcgc
     1921 tgcaattgct gccgcgctaa aagtcgcaaa agaattagga aaaggcaaga aggtattagc
     1981 tgtggttccc gacaatggtg aacgttattt atctacagcc ctttaccaag agatataagg
     2041 cacttggttt ttctccagat aggtttatgt aaaaaacttt taaagatgaa aagaacacac
     2101 aaaaatttat gatgagaaaa attatttgaa tagagacgta gaatagtgaa cgcgactgtt
     2161 ttacgtcttt tttcattaaa atacaataaa attgaatttt cttttcatgt taagtggatt
     2221 ttaaaatgta aaaatagtat gataagacga gaataacaac gtggggtgtt tacatggaaa
     2281 ataagttagt cgaagaggtt atcgaaaagt taaaaaaaga gaacattcga atcacacctc
     2341 aacggtacgc ggttttagaa tatttgattg aacatcattc ccatccaacg gctgatgaga
     2401 tttataaagc acttgaacat cggtttccaa atatgagtgt tgcgactgtt tacaataacc
     2461 ttcgcttatt tacttcgatt ggatttgttc aagaaatgaa gtacggcgat gcttctagcc
     2521 gatttgattt cagttcaaag cgtcattatc atgtaatttg tgaaaactgc ggtaagattg
     2581 ttgattttca ttacccaggg cttgaagata tagaaatggc tgcaagcaga ctgactgatt
     2641 ttgagattaa tgaacatcgg ttggaattgt atggactctg tccggattgt aaagagtcag
     2701 caaaaaaggc gcaaatgtaa aaacagtttc tacaagtgtt atacctaaaa aaagctagct
     2761 gtgtaaaaaa aacgctagct tttttatttt tttgtctttt attcacaatc ttagatataa
     2821 aagtgaatat tattaaaata agaatcttgt agatattggg ttcttatgct tgaaaaggaa
     2881 tgaaactaca aacaaacctt tgtgaattca caagcattaa actgttgtat ccgttttatt
     2941 tctgttatag tagttttgtc gaaggacaaa atgttaatcg gagggaccat aaatgaaagt
     3001 agtagtaatt ggctgtactc atgcaggtac tgcagctgta aaaagtattt taaaaaatca
     3061 tccagaagca gaagtgacag tatatgaaag aaatgacaat atttctttct tatcttgcgg
     3121 tatcgcactt tatgtcggcg gagtagtaaa ggacccagca ggcttgttct actcaaatcc
     3181 tgaagaatta tcttcattag gagcaacagt taaaatggaa cacgatgtaa cagacgtcga
     3241 tacagaaaat aaaacagtaa cggcaaaaga tctgaaaaca ggagaaacag aaacggtttc
     3301 ttatgataaa ttagtgatga caactggttc atggcctatt atcccaccga ttagtggaat
     3361 cgatgcgaaa aatgtactcc tatgcaaaaa ctacaatcaa gcaaatgaaa ttattgcaca
     3421 agcgaaagaa gcaaaacgtg tagtaattgt tggtggtgga tatatcggta ttgaattagt
     3481 agaagctttt gtcgaatctg gaaaacaagt gacattgatt gatggattag atcgcatctt
     3541 gaataaatat ctagataaac cattcacaga tatcttagaa aaagaattga cagaccgcgg
     3601 tgttactctt gcgctaggcg aaaatgttac tgaatttatc acagatgaag aaggaaaagt
     3661 gaaacaagta gctacaccaa cagatacatt tgatacagat atggtcattt tatgtgtggg
     3721 cttccgtcca aatacaaaac tgatcgaagg aaaagtagat acactgccaa acggggcaat
     3781 caaagtgaat gaatacatgc agacaagtaa tccagacatt tttgcagctg gagactctgc
     3841 agtagtcaac tacaatccaa gtggcacgca aaactatatt cctttggcaa caaatgccgt
     3901 tcgtcaaggt ttgcttgtgg gaaataactt gacagatcat aaaatggcgt atcgtggtac
     3961 tcaaggaact tcaggacttt acctatttgg ctggacgatc ggttcgacag gtgtgaccaa
     4021 agaaagcgca actttgaacg atctagaagt ccaagcgact gtatttgaag ataattatcg
     4081 tccagagttc atgccaacta ctgaaaaagt aatgatggag ctagtctatg aaaaaggaac
     4141 gaatcgtatc gtaggtgctc agttcatgtc caaatacgac attacacaat cagcaaatac
     4201 catgtcttta gctgttcaaa ataaaatgac tgtagaagat ctcgcacttt cagatttctt
     4261 cttccaacca cattttgacc gcccatggaa ttacttgaac ctacttgcac aagcagcgct
     4321 aggcgaaatc gaaactgcac aataaagaaa aagggttgtg acacaatttt gtcacgaccc
     4381 tctgtctttt tttgtgaaaa gtacaattag ttgtctttct tcgaattttt tgtcacaata
     4441 agcagcaaag ataaagctgt tacataaaag aacaagcagc tttatttgat tttgaaaaga
     4501 aaggtgagaa agaagatgaa taaagaatat tttgtccaac aagatgcatt tttagaagat
     4561 tataaaagtg cttcgaagaa attaacgatc aatattgatg agttggcaga tcaagtactc
     4621 tctcagttga atgaaacgca agaggaatat tacacgatgc cagcaaatga cgccaaagat
     4681 aatgtttctc atcgttttcc tttcagtaga cgcatctact cagatgaaaa tgacggcaca
     4741 ttgaatacag agtacacata tgaaggtcag ccatatgtgc tagaaactga tgatgatctt
     4801 taaagacagt ttttgaaaag gccgctcatc cttaagtgat gacaaaaaat catcacaatt
     4861 accgatgact gtctctttac tatcttttaa tcagaaaaag gggttatgac aagctttgtc
     4921 aacccctttt ttt
//
LOCUS       DAXQKX010000112         4757 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.117, whole genome shotgun sequence.
ACCESSION   DAXQKX010000112 DAXQKX010000000
VERSION     DAXQKX010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4757
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.117"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            192..290
                     /locus_tag="ACF3MF_002729"
                     /pseudo
     CDS             192..290
                     /locus_tag="ACF3MF_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558064.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(513..743)
                     /locus_tag="ACF3MF_002730"
     CDS             complement(513..743)
                     /locus_tag="ACF3MF_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HFE3928624.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEQEPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(973..1791)
                     /locus_tag="ACF3MF_002731"
     CDS             complement(973..1791)
                     /locus_tag="ACF3MF_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFE3928625.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            1952..2641
                     /locus_tag="ACF3MF_002732"
     CDS             1952..2641
                     /locus_tag="ACF3MF_002732"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HFE3928626.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            2655..4157
                     /locus_tag="ACF3MF_002733"
     CDS             2655..4157
                     /locus_tag="ACF3MF_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFE3928627.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            4170..4646
                     /locus_tag="ACF3MF_002734"
     CDS             4170..4646
                     /locus_tag="ACF3MF_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFE3928628.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
BASE COUNT         1593 a          690 c          845 g         1629 t
ORIGIN      
        1 accccttcta gggggattaa aaatacaccc gtcctcacgg gtgtatgggt tactgataga
       61 cttgatttta actggtgtca gaaacttatg tccagaaagg gtgatgaaat tttggcaatt
      121 tacggctatt caagaattag cacaagcaac caagattaca aaacacaaat tcaaacatta
      181 gaaaatgctg gcgcagaaat aatcttccta gaaaatcact ggattatcga acacctttgg
      241 aagtattttt gagttacgta agtattgatg atctgtctaa cttaatttga caattaagag
      301 tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat gaactaataa
      361 ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc ataaactttt
      421 aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca taacattgaa
      481 gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt cttataaaca
      541 agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt tatagaaaac
      601 attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc agtaggttcc
      661 tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt atttaagaga
      721 ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta cacgtttttc
      781 tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc aagaaccgta
      841 ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa taagctatca
      901 agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta ggtttagcta
      961 agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt tttctcttaa
     1021 ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat cacaaatata
     1081 aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa tggctgtttg
     1141 taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta tagcaataat
     1201 ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg ttttcccaga
     1261 taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt gggcttgaaa
     1321 atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat tttctaaatc
     1381 aagactagta tttccactag atcccactcc aaatatatat atgttttttg attgagtgat
     1441 cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg aatagagagc
     1501 ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat gttctttttt
     1561 ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag aaaaaccaat
     1621 tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct taatatcact
     1681 catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga cttttttttc
     1741 agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca tacaaactcc
     1801 tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact cctaaatact
     1861 ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag ttgttatcca
     1921 aaaataataa aaaattggag tgtttaggat aatggataaa aagaggtttt tagatcttat
     1981 ttcaaaaggt ttgattgttt cctgtcaagc attacctggt gaaccatttt acaaagagga
     2041 agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag ttggtatacg
     2101 tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac caatgattgg
     2161 aattattaaa agagattatc caccagaatc tccattcatt actgccacta tgagagaagt
     2221 agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc ttagaaatcg
     2281 acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat atcctcatca
     2341 gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata aagcaggaat
     2401 agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac aagatgggcc
     2461 agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg ctgagggaag
     2521 gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag gtattgttgt
     2581 gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag cattaagtta
     2641 gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc atgttaccaa
     2701 ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta acaaatgaga
     2761 gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt ttaagtatta
     2821 tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca attggtattg
     2881 ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga gtagcttatc
     2941 tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa gatgcaacac
     3001 tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt ttacacaatc
     3061 gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca agatttattc
     3121 cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta atttggccac
     3181 caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt agtttaggaa
     3241 cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac cacaccattt
     3301 accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga tcaacaattg
     3361 ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact ggtctgttta
     3421 cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttgga ttaccagcag
     3481 catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat ggtgggcttt
     3541 attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt gaatatatgt
     3601 ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga ttatcttttt
     3661 attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt ttgatcgact
     3721 ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa ttaattcctt
     3781 ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc aaaaaattta
     3841 aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa gtaataaaca
     3901 aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt ggaaaagaaa
     3961 atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg aatggggaga
     4021 ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa gtgaagggtg
     4081 gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc aatcaaatat
     4141 taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag aaaaaacaag
     4201 aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta aatgatcctg
     4261 tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt tcaaaaattt
     4321 atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct attaatataa
     4381 aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt gaattacaag
     4441 gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa acctcgttgg
     4501 ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt atagttgttt
     4561 ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt gctcatggga
     4621 attcatgtgg aaaaatcact ttttaaaaaa gtgtatataa aaagctataa aataagctaa
     4681 ataggatatt tgtcaaatga agttggtgaa cagaaagaac tgttttcttt ctgttcattt
     4741 ttttatttta ttagtaa
//
LOCUS       DAXQKX010000113         4662 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.118, whole genome shotgun sequence.
ACCESSION   DAXQKX010000113 DAXQKX010000000
VERSION     DAXQKX010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4662
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.118"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            687..1046
                     /locus_tag="ACF3MF_002735"
     CDS             687..1046
                     /locus_tag="ACF3MF_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFE3928629.1"
                     /translation="MSDNLFLEVQPEVFKQVPRLKDGFLLTLNDGSNQFSSAEGCCMI
                     GDHFLLVSTQHYIPAYDLTIPCEEATVKTSEYDTTFINGHLVLEVTPSNQTIRLKNES
                     GILDSNVQVYFDSSDAS"
     gene            complement(1119..1937)
                     /locus_tag="ACF3MF_002736"
     CDS             complement(1119..1937)
                     /locus_tag="ACF3MF_002736"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFE3928630.1"
                     /translation="MNKNPHNLKLVAVDMDGTFARTDYTYDIPRFKAVLSRMKAVDCQ
                     FVVASGNQYYQLRSLFPNYYDELSFVAENGAFVKDKTEVLFSADMPRKAIEVVLDLCK
                     DYPEVKNVMCGLNSAYCERGKVSQAFFDLTNIYYHRLEWVADFAEVQDKILKFAPTMP
                     VEKTEFYVELFREKLAGLLVPTSSGHGSVDLILSECHKTFGLKMLVERLGINPDQCVA
                     FGDGGNDIEMLEYCGLSYEMDNATEAVKQVAKHQCPSNDEDGVLVTLDRLFPNT"
     gene            complement(2351..2782)
                     /locus_tag="ACF3MF_002737"
     CDS             complement(2351..2782)
                     /locus_tag="ACF3MF_002737"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFE3928631.1"
                     /translation="MLNKRIANKNDYKLVLEIWEKSVKQTHDFLAEADFNFYKAIIPE
                     NLDEVKLYLWEDNGEIVGFSGVSAEELVMLFLDPDFIGKRYGSQILIELIETEDIKRI
                     DVNSQNKYAKHFYLSHGFEIESEEDLDGFGKPYPITHLVKK"
     gene            2883..3182
                     /locus_tag="ACF3MF_002738"
     CDS             2883..3182
                     /locus_tag="ACF3MF_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928632.1"
                     /translation="MTKIYFMLTSNSGVGSTTIFATRARRNIDDLLAFFSQYYDVSAN
                     YTKDKDMIDLLVLPEPFGPFNNERNLPVIQIPTILFLERDFEKIKTHIDAYLTKK"
     gene            complement(3227..3877)
                     /locus_tag="ACF3MF_002739"
     CDS             complement(3227..3877)
                     /locus_tag="ACF3MF_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036361 - racemase activity, acting on
                     amino acids and derivatives [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate/glutamate racemase family protein"
                     /protein_id="HFE3928633.1"
                     /translation="MPKVAVMAGTPIDTRMGADLLNEISCELLEVPISENPAQQTYFQ
                     TLPVFEKMHQIEVKIKDLQSKKIDLLLVYCNSLSASIDFDFLAKKYSMKIITPFQVYA
                     DLAQKHERIGVLTANGQGAAGIESVLVQHHSTIRVYNVTNLDWVHAVEAKIHPSIIVE
                     QFGLTDSMSFFMKNQVEAILIGCTHFPYFLTEYQSRTRIPCINPDDALIEKVKSIL"
BASE COUNT         1553 a          822 c          652 g         1635 t
ORIGIN      
        1 gacttccttt tttgtatgga ttttttcatt tacacaaaat attttacact ctctaattca
       61 tttttaccga taggctaaat cgtataaaaa ctaaccactt ttaatcatta ttttattctt
      121 agttttatgt gagataaatt aaccatttta agtttacaaa tgtaatcaat ttctattact
      181 ttataagtat cgtttacatt cgtcaacgat agagcttgaa atatttttat ttgaaaattt
      241 tgtatttaga tgattatgaa ctaatacagt gtcggaggat acttatgtat ttaaactaaa
      301 ctattttaga aaaaccagta atcctttgaa ttttctattg gaaaatgaag taaaatatta
      361 taagaataac ctttaaagtt gggcaactat tattcaaaca tctaaacata ctcctaagag
      421 aaatagatat ataatagact aaggaagcgt tttaaatatt gtagaaaata gagaaaattt
      481 atcagatctt cggtttaatt tttacagcgt taatcgctct tgatatgaat gagctctgat
      541 aaagccgaag taaattggcg atttgaaaag ttcaattatt tgagaataga atatttttta
      601 tatagaattg agttatagtt aagggggaat aggtgtgtta aataaaatgt caatttcaac
      661 tgtggaagtc gatggtggtc gtgaaaatga gcgataattt atttttagaa gtacaaccag
      721 aagtatttaa gcaagtacct cgtttaaagg atggattctt gttaacttta aatgatggct
      781 ctaatcaatt ttcttcagca gagggatgct gtatgattgg tgatcatttt ttattagttt
      841 ccacacaaca ttatattcca gcatatgatt taacaatacc ttgcgaagaa gcaacagtta
      901 aaacatctga atacgatact acctttatta atgggcattt agtattagag gtaactccat
      961 caaatcaaac aattcgttta aagaatgaaa gtggtatttt agatagcaat gtccaagtct
     1021 attttgactc atcagacgct tcgtaaatct gttctaaata tagttttaaa acctcgaata
     1081 tttcttatat cgaggttttt tgatgaatta cctagtgttt acgtgttagg gaacaatcga
     1141 tcgagcgtca ctaaaacacc gtcttcgtca tttgaaggac attgatgctt agcaacttgc
     1201 ttaacagctt ccgttgcatt atccatttca taactcagac cacaatactc caacatctca
     1261 atgtcattgc ccccatctcc aaaagcaacg cactggtcag gattaatccc caagcgctca
     1321 actaacattt tcaagccgaa agttttatgg cactcagaaa gaatcaagtc tacagaacca
     1381 tgaccactac tggtaggtac taatagcccg gctaattttt cacggaacaa ttcaacgtaa
     1441 aattcggttt tttcaacagg catagtcgga gcaaatttta aaattttatc ttgaacttct
     1501 gcaaaatcag ctacccattc taatctatgg taatagatat tggttagatc aaaaaatgct
     1561 tgactcacct ttcctctttc acagtaggca ctattcagac cacacatcac attttttact
     1621 tcaggatagt ctttacataa atcaaggacc acctcgatcg cttttctagg catatcggct
     1681 gaaaatagta cctctgtttt atctttaaca aaagcaccat tttcagcaac aaaacttaat
     1741 tcatcataat aatttggaaa taacgatctc aattggtagt attgatttcc acttgcaaca
     1801 acaaattgac aatcaacagc tttcattcgc gataaaacag ccttgaacct tgggatatcg
     1861 tatgtgtaat cagtacgagc aaatgttcca tccatatcta ctgctaccaa ctttagatta
     1921 tgaggattct tattcataaa aacactcctg tcgcctttga tatcttcatt atattgaaaa
     1981 agtattcaga cctaaagcag cctatttttc ttactccgtt aaaaataaga acatttctaa
     2041 tttcagttaa ctatctagat acatacaagc cattttttgt attaaaagct accgacctgt
     2101 ctttctccta acccacaggt cagcctaaat cagtgttgac ataagatttt tatcattttt
     2161 actttaactg attttctata actggtacat ccttggtcag ctagtatcat aagttgatcc
     2221 taagataagc accttattac tgaatgtaat acacaaattt gatctggata attcataacc
     2281 tagaaatagg ccatcaaaat aaaaatatta cttttattca tgttcaatca ggtaataaac
     2341 cattcatgaa ttattttttt actaaatgcg ttatagggta tggtttacca aaaccatcta
     2401 agtcttcttc agattcaatt tcaaatccat ggcttaaata aaaatgtttt gcatatttat
     2461 tttgactatt aacatcaatt ctttttatat cttcagtttc aatcagctca attaatattt
     2521 gactaccata tcgcttacca ataaaatctg gatcaagaaa tagcataact aattcttctg
     2581 cacttacacc actaaaaccg acaatttctc cgttatcttc ccataaataa agtttaacct
     2641 catctaagtt ctcaggaatg attgctttat aaaaattaaa atctgcttca gctagaaaat
     2701 catgggtttg ctttactgac ttctcccaaa tttctaaaac taatttataa tcatttttat
     2761 ttgctattct tttgtttaac atgctcttat tccccttttc ttataatttt aactttattt
     2821 gcaagcatag ttagtcaaac ataaagctac cgctatattt tatttaaaaa ggagaattcg
     2881 taatgactaa aatctatttt atgcttactt ctaatagtgg cgttggttct accacaatat
     2941 ttgcgacccg cgctagacgt aacattgatg atcttttagc ttttttctct cagtattatg
     3001 acgtatcagc aaattatacc aaagataagg atatgattga tctattggtg ctaccagagc
     3061 cctttggacc gtttaataat gagcgtaatt tgccggtcat tcagattccg actattttat
     3121 ttttggagag agactttgaa aaaataaaaa cacacattga tgcttatttg actaaaaaat
     3181 aaaacaaaaa aatcctaagt tattgtctgt gtcaaaccaa tgcttattaa agtattgatt
     3241 tgactttttc tattaatgca tcatctggat tgatacaagg aattctcgtt ctggactgat
     3301 attctgtaag aaaataagga aaatgagtac aaccgatcaa aatcgcttcg acttgatttt
     3361 tcataaaaaa actcattgaa tccgtcagtc caaattgttc tacaataata ctagggtgga
     3421 tctttgcttc caccgcatgt acccaatcca gattcgtgac attataaact cgtattgttg
     3481 aatggtgctg cactaaaaca ctttctattc cagccgctcc ttgaccatta gcggtcaaca
     3541 caccaatacg ctcgtgtttt tgagccaaat ccgcatatac ttgaaatggt gtgataatct
     3601 tcattgaata tttcttagcc agaaaatcaa aatcaatcga tgcactcagt gaattacaat
     3661 aaaccaacag taaatcaatt tttttactct gtagatcttt tattttcact tcaatttggt
     3721 gcatcttttc gaagactgga agtgtttgga aataggtctg ttgagctgga ttttctgaaa
     3781 taggtacttc taacaattca caggaaattt cgttcaatag atcagctccc atcctagtat
     3841 caataggtgt tcccgccatt acagccactt taggcatact gatcattcct tcaaaatgaa
     3901 tttttgccta ttatactcta aaaatcaaat ttgaagaata gcgatccgga agttaaactg
     3961 aaaattctaa agtaattctt tgatttattt agattcaact taacatcttt agtgtactaa
     4021 taaaaaattc gctcaatatt tctagctata ctttatatcc caatatacat aagcttccct
     4081 atttttacag gttacaagtg aaaattaaac tgcttatatt gattgcattt aactactaag
     4141 gatgatgctt gttgttagta tgtcagaaaa atccaacagt atagttttgt cagcacattc
     4201 atcattcttt cctgtaaaac aaaaagagag tagacctatt cttccacttc atcatcgtta
     4261 tctaaaacag caattttctg ctgtaaaata gtcataaatt ttttctagta gccttctctt
     4321 taaactcatc ataatctcaa ttatcttttt ttaagatttg ctcaactttt tccctcttga
     4381 ttattgcaat tcacacctta taaagtttta aactaatggg agacgtcatc tagcttaact
     4441 tatagtccct gctccgttta atctacactt gttatcttgt attattgata aaagatagac
     4501 tagttacgga ttgaaattag gttgcaattc taaaaatcca gtagtctaaa atcatgctta
     4561 ttaatttaca atatcttaaa aaagggtttt aacttaataa cagaaaaaat tattcatggg
     4621 cgaaaaaatg attaggatgg cgtaaaagtt aaagatctta gt
//
LOCUS       DAXQKX010000114         4516 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.119, whole genome shotgun sequence.
ACCESSION   DAXQKX010000114 DAXQKX010000000
VERSION     DAXQKX010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4516
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.119"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..947)
                     /locus_tag="ACF3MF_002740"
     CDS             complement(<1..947)
                     /locus_tag="ACF3MF_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFE3928634.1"
                     /translation="MHKISVIVPAYNVENYLENCLESISNQTHSNIEIIVVDDGSPDR
                     SGEIAEEYKKKDMRLKVIHQVNGGLSAARNSGLDSATGDFVCFIDSDDWIEPDYLELL
                     YFGTQTYGADISVLKIKKISSLEQLKEHTIAERKWEIFDREQAMKNLFINNKIGYSAN
                     NKLFNRNLFDNIRFPLGKLMEDKATTYLLIDHSEKVAVNSSAKYHYYQSPKSILRGSF
                     NPRIFDSFEVHEDILVFIDKFYPELSINVRTRYVYEAIRMMMTMIKNNYTNKEDYLRS
                     INILQRFEKEVKIDPDFSPKLKKLVKFLLINKNLPYYMS"
     gene            complement(1061..2050)
                     /locus_tag="ACF3MF_002741"
     CDS             complement(1061..2050)
                     /locus_tag="ACF3MF_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFE3928635.1"
                     /translation="MNQNLEKQTKLSIIIPFYNAKNTLRRAVDSVLTQGYPNIEILLI
                     DDGSTDGSSDIGDEIANLESKVACYHLENAGPSVARNYGIKEATGNLVGFLDSDDYFL
                     PDCFNNVLKDYHRNHPDIIAFGLSKGKNIENANLFVPEKKIGCSSEEAIEQMFRSKAV
                     DFYVWNKFFKRELFNHIVFPENKLYEDMVPMYEAFRAASKIDILPFSGIFYYQNNDSI
                     VYQSFNSKQYDNILQRKILVDEVKKDYPRLINLANARLVDGYLSTGFKITGKNQNQKE
                     KQKYYNQSKREIKSIYSKIRSNNEISIAKKLALFLYLINPKTYFILYKKVLKK"
     gene            complement(2022..2852)
                     /locus_tag="ACF3MF_002742"
     CDS             complement(2022..2852)
                     /locus_tag="ACF3MF_002742"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFE3928636.1"
                     /translation="MENKNISILLSLYDKEKPEYLKEALASIFEQTVMPAEIVLVYDG
                     PINEKLQAVVTYFQQKVPHLFTVVKLEKNQGLGIALATGLEHTKNRLVARMDTDDIME
                     PHRLEKQLEIFQEYPEIAIVGSNIEEFTGTLSNVIGRRIVPEYNDEIRVFSKRRNPFN
                     HMTVMFDKNAILEVGNYRPLIGFEDYYLWVRLLKAGYKGYNIQEILVHARAGADMYAR
                     RGGSKYLLPGIKGRYRVWKDGLGSLKDFLIVICGHLVISLLPNKIRGKVYESKLRKTN
                     "
     gene            complement(2890..4281)
                     /locus_tag="ACF3MF_002743"
     CDS             complement(2890..4281)
                     /locus_tag="ACF3MF_002743"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFE3928637.1"
                     /translation="MNKNGEWNAARRIFIILMDVLVLNVSIYLSFLLKFQGEVPVRNL
                     ETFQHSAIFISIIFIALNILLGAYVFYNRMISDIVFITVIGQVLIALGIMVVTFAGRW
                     FAFPRGVILISFILGTILLSVYRIVVYKLYLRVSRDKKVLIVGLEKDVAPAIQNFQSK
                     KNNKHKVEAVAIDNYYENTKKLIDDMDIVYLASKIPEDEKINIYQLVTKKEKKLFLNT
                     TFENLTMINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLILLILASPFMLIT
                     AILVKTTSPGPIIYKQVRITKNQKEFSIYKFRSMSATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNEENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLLLDLKILLQTIKILFDKMSSQGLDEDENISS
                     LAESAFPKEKTYR"
BASE COUNT         1434 a          832 c          604 g         1646 t
ORIGIN      
        1 cttgacatat agtaaggcaa gtttttattt attaataaaa actttactaa tttttttaat
       61 tttggtgaaa agtcgggatc aattttcact tctttttcaa agcgttgtaa aatatttata
      121 gaacgtaaat aatcttcttt attggtatag ttatttttaa tcattgtcat catcatcctt
      181 attgcttcat agacatagcg agttctaaca ttaattgata attccggata aaacttatct
      241 atgaatacta gtatatcttc atggacttca aaagaatcaa aaattctagg attgaagctt
      301 cctctcagta tacttttagg gctttggtaa tagtgatatt tagcagatga attgacagca
      361 actttttcgg aatgatcgat caacaaataa gtagtagcct tatcttccat taatttaccc
      421 agtgggaatc ttatattatc aaataaattt ctattgaata atttattatt tgcagaatag
      481 ccaattttat tatttataaa taagtttttc attgcttgtt ctctatcaaa tatttcccat
      541 tttctctcag caattgtatg ttcttttagt tgttctaaac ttgaaatctt ttttattttt
      601 agcaccgaga tatctgctcc ataagtttgc gtaccaaaat atagtaactc aagatagtct
      661 ggttctatcc aatcatcgct gtcaataaag cacacaaaat ctcctgttgc agaatcaaga
      721 ccagaattcc tagccgcact taaaccacca ttcacttgat gtatcacttt taatcgcata
      781 tctttctttt tatattcttc tgcaatttcc ccacttcgat ccggggaacc atcatcgact
      841 actattattt caatatttga atgtgtctga ttggaaatag attctaagca gttttctaaa
      901 tagttttcta cgttatatgc gggtactata acactaattt tatgcactct cttcacttcc
      961 taaaaatcat cttttttatt tttacaaatg tatcattacc agtaacaatt ttagtcttcc
     1021 gaagttaata aacataaaaa ataacatatc gaaaaaaact ttattttttt agaacttttt
     1081 tatataaaat aaaataagtt ttaggattaa ttaagtataa aaataaagct aattttttag
     1141 caattgatat ctcattgtta cttcttattt ttgaatatat actttttatt tctcttttag
     1201 actgattata atatttttgt ttttctttct gattttgatt tttgccagta attttaaacc
     1261 ctgttgaaag atatccgtct actaaccgag cattggccaa attaataagt cgaggataat
     1321 ctttctttac ttcatcaact aatatttttc tctgcaaaat attatcatac tgttttgaat
     1381 taaaagactg ataaacgatg ctatcgttat tttgataata aaaaatacct gaaaatggca
     1441 aaatatcaat tttactagcc gccctaaaag cttcatacat aggaaccata tcctcatata
     1501 atttattttc tggaaaaact atatgattga ataattccct tttaaaaaat ttattccata
     1561 cgtaaaagtc cactgcctta cttctaaaca tttgctcaat tgcttcttca cttgaacaac
     1621 caatcttctt ttcgggaaca aataaatttg cattttctat attttttcct ttacttaatc
     1681 caaaagcaat gatatcgggg tgattcctat ggtagtcttt caaaacatta ttaaaacaat
     1741 caggtaaaaa ataatcgtca ctatctaaaa atcctaccaa atttccagtt gcttctttta
     1801 tcccatagtt cctagcaact gatggaccag cgttttccaa gtgataacat gctactttac
     1861 tctctagatt agcaatttcg tcaccaatgt cactactacc atctgtagat ccatcatcaa
     1921 ttaacaagat ttcaatattg ggataacctt gcgttaagac gctgtctaca gctcttctta
     1981 aagtattctt tgcattgtaa aaaggtatga ttatagaaag tttagtttgt ttttctaagt
     2041 tttgattcat atacttttcc cctaatttta ttcggtaata aactaattac aagatgtccg
     2101 caaataacta tcagaaaatc ttttagtgat cctagaccat ctttccatac gcgatatcgg
     2161 cctttaattc ctggtaaaag atatttactt cctccacgtc tagcatacat gtcagcacct
     2221 gctctagcat gtactagaat ctcttggata ttatatcctt tatatcccgc cttcaatagt
     2281 cttacccaca aataataatc ttcaaatcca attaatgggc gatagtttcc cacttctaaa
     2341 atagcatttt tatcaaacat gactgtcata tgattaaaag ggtttcttct tttcgaaaac
     2401 acacggattt catcattata ctcaggtaca atccttcttc cgataacatt gctaagtgtg
     2461 ccagtaaatt cttcaatatt actcccaaca atcgctattt ctggatattc ttggaagatc
     2521 tctaattgtt tttccaatct gtgtggttcc atgatgtcat ctgtatccat tctggccact
     2581 aagcgatttt tagtatgttc taatccagtt gctaaagcaa tccccaatcc ttgatttttt
     2641 tctaatttta caactgtaaa caagtgagga actttttgct ggaaataagt gacaactgcc
     2701 tgaagcttct catttatagg gccatcataa accaatacga tttctgccgg catcaccgtt
     2761 tgctcaaaga tactagctaa tgcttccttt aaatattccg gcttttcttt atcatacaaa
     2821 gaaagcagta tacttatatt tttattttcc aatgttctct cctacttctt tgctcaaaat
     2881 ttttccaatc taacgatacg ttttttcttt tggaaatgca ctttctgcta atgaactgat
     2941 attttcatct tcatctagtc cttgtgagga catcttatca aataagattt tgattgtttg
     3001 aagtaaaatc ttcaaatcta atagtaagga atactttttg atatacaaca aatcaaaacg
     3061 tagtttactg ttataatctg atacatattt tccgtatact tgtgcatatc cggtaattcc
     3121 cgcacgtaca ttgtgtctta agtaataata aggattttct tcattgaact gatcaacgaa
     3181 aaatggtctt tctggccttg gaccgacaat cgacatatcg cctttcaata cattaaagat
     3241 ttgaggtaat tcgtcaaaac gtacagcacg gataaattta cctactggtg tcacacgtgc
     3301 atcgttactt ttagccaaga ctggtcctga ttttgcttca gctgtcgcac tcatggaacg
     3361 gaatttatag attgaaaatt ccttttgatt tttcgtaata cgtacttgtt tatagatgat
     3421 tggtccaggt gaagttgttt ttaccaaaat cgctgtgatt agcataaaag gtgaggcgag
     3481 gatcagtaaa ataagcgaaa cgatgatatc aaagagacgc ttgaatagtt cgtattctgg
     3541 ttggattctg aacccagaag cttcaatgat gctttcatct tcaaaattca taatattcgg
     3601 atttatcatt gtcagattct caaaagtcgt atttaaaaat aatttcttct cttttttagt
     3661 cactaattga taaatgttga ttttttcatc ttctgggatt ttagaagcca aatagacgat
     3721 atccatatca tcgatcaatt tttttgtatt ttcgtaataa ttatcgattg ccactgcttc
     3781 aaccttatgt ttattgtttt tcttagattg aaaattttgg atagctggtg cgacatcttt
     3841 ctccaaaccc acgataagga ctttcttatc acgactgact cttaagtaca gtttgtaaac
     3901 gactatccgg taaacactaa gtaatatcgt acctaggata aacgagatca aaatgacgcc
     3961 acgcggaaat gcaaaccatc ggccagcaaa agtaactacc atgatcccca atgctattag
     4021 tacttgtcca ataacagtaa tgaagacaat atcactgatc attcggttat agaatacata
     4081 agctcctaac aaaatattca acgcaataaa gatgatggaa ataaaaattg ctgaatgctg
     4141 aaaggtttct aagtttctca ctggtacttc tccctggaat ttcagcaaaa aactaagata
     4201 gatcgataca tttaatacaa gtacatccat aagaataatg aatattctgc gtgccgcatt
     4261 ccactcccca tttttattca tatatacact cctaaccata aaataatgcc tctatcatct
     4321 taccatagca aagtttaaaa acctagtgaa taaccaaatt gtaaaggaaa ttaaaagaaa
     4381 cggggaaaag cgtttattgt ctgtttatat gtgtatttct gcataacaga aagttgtctc
     4441 agaagtccca tcacttcctt tatgctgaac tagtattctc ctgctaattc cttattcaca
     4501 agttacaata ttcata
//
LOCUS       DAXQKX010000115         4174 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.122, whole genome shotgun sequence.
ACCESSION   DAXQKX010000115 DAXQKX010000000
VERSION     DAXQKX010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4174
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.122"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            155..316
                     /locus_tag="ACF3MF_002744"
     CDS             155..316
                     /locus_tag="ACF3MF_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HFE3928638.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
     gene            335..1612
                     /locus_tag="ACF3MF_002745"
     CDS             335..1612
                     /locus_tag="ACF3MF_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFE3928639.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1622..2278
                     /locus_tag="ACF3MF_002746"
     CDS             1622..2278
                     /locus_tag="ACF3MF_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3928640.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            2278..3654
                     /locus_tag="ACF3MF_002747"
     CDS             2278..3654
                     /locus_tag="ACF3MF_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFE3928641.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            3784..>4174
                     /locus_tag="ACF3MF_002748"
     CDS             3784..>4174
                     /locus_tag="ACF3MF_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014479650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFE3928642.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDIADCRQKLFQTRNSSLEQLF"
BASE COUNT         1646 a          466 c          739 g         1323 t
ORIGIN      
        1 ctgcgcgagg cttaccagcg agatagagat cgacgatttg ttgtttgaat tcttttgaat
       61 aggttcttcg ttgacgtctt ggcatgaaaa atcctccagt gtgtttttta ttattctaca
      121 caccttattt tttctgtcta gtctagtgta gccgattcag gataaggata agtgtattaa
      181 ttgtggaaaa tgtaaaaaag tttgccaaat gaataaagat tcagttgaga attgcaatca
      241 tctggagtgt atcagatgtg gacgatgtaa aaatgcttgt ccagtggatg caattagtta
      301 tggagtaaga aaatagagag gagtagttag gaaagtgata aaaaatgcta tagcatatat
      361 tacaagaaag aaaaatagaa ctttaataat ttttatcata ttaactatag ttctttcttg
      421 cttgtattct tgtttaacaa taatgaaatc aagcaatgaa atagaaaagg ctttatatga
      481 aagttctaat tcttcaatat caataacaaa aaaagatggt aaatatttta atgttaatca
      541 atttaaagat attgaaaaat taaaagaaat tgaagaaaaa ataattcaat atgatggatt
      601 agcaaaatta aaagatgcta aagtagttag cggagaacaa agaataaata gagaagattt
      661 atctgacgaa tttaagaatg ttgtttcact cgaagctaca aataatacta aaagaaatat
      721 tttatttagt agtggagtat ttacaattaa agaaggtaaa aatatagaag aaaatgataa
      781 gaattcaatt attgttcatg aagaatttgc taaacaaaac aatctaaaat taggtgatga
      841 agttgatctt gaattactag atattgaaaa aagtggaaaa ataaaaagtc ataaatttaa
      901 aattataggg atcttttctg gtaaaaaaca ggaaacatat acaggattat cttctgattt
      961 tagtgaaaat atggtgtttg tagattattc aacaagccaa gagatattaa ataattcaga
     1021 aaataatgaa attgcaaata aaattttaat gtattctggt agtgcagaat ctacagactt
     1081 agccttaaac aaattgaaag agcttaaaat tgatgagtca aagtattttg ttgaaaaaga
     1141 ttctaatgcg tttgaagagt ctttagagtc agtgagtgga ataaaatata taataaaagt
     1201 aatgacttat tctattatgt taggtgggat ggttgttctt tcattaatct tgattctatg
     1261 gttaagggaa agaatttatg aaataggtat attcttatct attggaacat ctaagataca
     1321 aattataatg caatttatat tcgagttaat attcatatcg ataccaagta taatatcttc
     1381 cttattttta ggaaatgtat tactaaaagt aattgtagat ggattcatta actcagagga
     1441 ttcaatgatt tccggtggaa gtttaataaa taatagtagt tttatgtcaa atataacaac
     1501 acttggacaa agttatttaa tattaataag tattattgtt ttatcagttg tatttgcttc
     1561 ttcattaatg ttaatcaaga agcctaaaga aatcttatca aaaataagtt aggagaaaat
     1621 aatggatata ttagaaataa agaatgtagc atatagttat gcaaattcta aagaaaaagt
     1681 tttgtcagga gtaaatcaaa aatttgaact tgggaagttt tatgcgatag taggaaagtc
     1741 aggaacagga aaatctacac ttctttcctt acttgctgga cttgataaac ctcaaacagg
     1801 aaaaatattg tttaagaatg aagatataca aaataaagga tatagtaatc atagaaaaaa
     1861 taatatatct ttagtatttc aaaactataa tttaatagat tatttatcac caattgaaaa
     1921 tattagatta gtaaataaat cagcagatga aagtatcttg tttgaactag gtttagataa
     1981 aaaacaaata aaaagaaatg ttatgaaatt atctggtgga cagcaacaaa gagtagctat
     2041 tgctagagca ttggtatcag atgctccaat aatactagct gatgagccta ctggtaatct
     2101 agacagtgtt actgctggag aaataattaa tatattaaag acattagcta aagatagaaa
     2161 taaatgtgta atagttgtaa cacatagtaa ggaagtagca gattctgcgg atatcatttt
     2221 agaactaagt ggtaaaaagt tgaaaaaagt aaataaaatg aatttggagg ttgaataatg
     2281 ataaaaaatg catttgctta tgtaactaga aaaagtttaa aatcattaat tatcatatta
     2341 gttattttat ctatgtcaac tttaagtctc attagtttat ctattaaaga tgctacggac
     2401 agagcttcaa aagaaacatt tgctaatata acaaatagtt tttctatgga gataaataga
     2461 caagtaaatc caggaacacc tagaggtggg ggaaatgtaa aaggtgaaga tattaaaaag
     2521 atatctcaaa cagatagtat agactcctat gtaaaaagaa taaacagtgt tgcagattta
     2581 gttgattatg atattattga aactcaagag actcttgcga atcaatcacc tgaaagagca
     2641 aagaatttta aaagaacagt tatgttaact ggggttaacg actcaacaaa agaaacaaaa
     2701 tttgtatcag aagcatataa attagtagaa ggaaagcatt tagaaaatga agataaaaat
     2761 aaaatcttaa tgcataaaga tttagctgaa aaaaataacc ttaaagttgg agataagata
     2821 aaaataaaat ctaatttatt tgatgctgat aatgagaaag gtgcagatga aacagtagaa
     2881 gtagaaatta aaggtctatt cgatgggcat aatagcggtg tagtaagtgc agcacaagaa
     2941 ctatacgaaa atacattaat cactgatatt catacagctg ctaaagttta tggtaatacc
     3001 gaagatacag ctgtatacca agatgcaaca ttctttgtaa aaggtgataa gaatcttgat
     3061 agtgtaataa aagatcttgg gaaattagat ataaattgga gagaatataa tttgattaaa
     3121 agttcatcaa attaccctgc attacaacaa tctatatcag gtatttactc aatttcaaat
     3181 aaattatttt ttggctcatt aatatttgca ggagttgtag tttcattatt attattctta
     3241 tggatgaatg ctagaaagaa agaaatagca gtattactat cattaggtat atcaaaatta
     3301 gaaatttttg gtcaattcct aattgagatg gtatttatat caatccccgc attcgttggt
     3361 tcctatttct tagctcaata tacagctgac aagcttggga ataatatatt gaataaggtt
     3421 actggtgata tagctaaaca aatagctaaa caatctgcat ctagccaatt aggtggtggg
     3481 gcagaagctg aaggatttaa caagacatta tcaagtttag atatcaatgt attacctaaa
     3541 ttcatgattt atgtagttat atttatgagt ttagtacttc ttgtatcatt gattatttct
     3601 tcattcaata tattaagaag gaatccaaaa gaattattaa ttgacaataa ttaaaatttt
     3661 cggtgctttt tagcaccaaa aatgagagtg taatataaac cgtgtaagta accatcaatc
     3721 ctaggcgggt ggttgcttca cggtttttat ttttctaaaa taagatcaag aggtgattac
     3781 acgatggcta gaaagaaaag aaatcctgat gctgagaagt tagctgaatc cattttgaat
     3841 acttatcaac ccgaatctgt agaggatatg caagatgttt taaaagatgt gtttggtccc
     3901 ttatttgaaa aaatgcttca aggagaattg aataaccatt tagggtatga cgcccattct
     3961 aaagagccaa agaaacatga caatcgacga aacggttatg gcaataagac gcttaaaacg
     4021 agctttggta aagtaaacat tgatgttccc agagaccggg aggcttcttt tgaacctgag
     4081 ttgattccta atagaaaacg agatgtctcc gacatcgcag actgtagaca aaagctgttc
     4141 caaactcgta actcgagctt ggaacagctt ttta
//
LOCUS       DAXQKX010000116         4110 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.123, whole genome shotgun sequence.
ACCESSION   DAXQKX010000116 DAXQKX010000000
VERSION     DAXQKX010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4110)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4110)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4110
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.123"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(175..861)
                     /locus_tag="ACF3MF_002749"
     CDS             complement(175..861)
                     /locus_tag="ACF3MF_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFE3928643.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTHLNRFR
                     WLRLTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDY
                     FEDIQDRPIK"
     gene            complement(997..1191)
                     /locus_tag="ACF3MF_002750"
     CDS             complement(997..1191)
                     /locus_tag="ACF3MF_002750"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928644.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(1241..1681)
                     /locus_tag="ACF3MF_002751"
     CDS             complement(1241..1681)
                     /locus_tag="ACF3MF_002751"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HFE3928645.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELEQLFQAYASLDDVNS"
     gene            complement(1685..2530)
                     /locus_tag="ACF3MF_002752"
     CDS             complement(1685..2530)
                     /locus_tag="ACF3MF_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HFE3928646.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVDWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLVANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAVYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            2679..4097
                     /gene="pepV"
                     /locus_tag="ACF3MF_002753"
     CDS             2679..4097
                     /gene="pepV"
                     /locus_tag="ACF3MF_002753"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HFE3928647.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
BASE COUNT         1229 a          803 c          828 g         1250 t
ORIGIN      
        1 tttacttggc tgttcttatt acttgatgca gggcagcttt ttcacaacct ctcaataaac
       61 ggtgtgcaat cagctgaccc tcggtattag ctcaaaaaaa acggcaaaat atgaggaact
      121 attttgccgt ttatttctct aatactcagg tcaaaacgct gattccaaaa cctcttattt
      181 gatgggtctg tcctgaatat cttcaaaata atcggggtaa ttatgaatca cgtattcttg
      241 ctcctcgata atcatatgta aatgcatcgt gcaaagaaat ccgacttcat caaagttatg
      301 atcaatcatt gattgaagca ttgtctgatg ttcatctaat actcgacccc agtctaattc
      361 tgaaatcgtc aaacgtaacc atctgaaacg gttcaagtgc gtactataac tttctagcca
      421 atcccaaatt tctcgttttc cagcaatttc ataacaagtt cggtgaaaat cagtatccaa
      481 atcaaaaaaa gcttttttat tttgagcgat cactgcctga tcggtttgtt ctagtatttt
      541 ttctagttta gcttgatctt gcttggtcat tttcgcactg cattcttgca ggatcggttt
      601 ttccaacttt tcccgcgtat aacgggctaa tgaagcagat cggatatcga tttttgaaac
      661 ataagtgccg gactgtggaa tggtttttac aagctcttga ttgcgcagtt ggatcagtgc
      721 ttctcgaatc ggtgtacgcc cgatagctag ttgttcttct aacactttat cggagatttt
      781 acttccgggt gctaactcgg aataaatgat ttgtttacgt atagattcat aagcttgctg
      841 ttgcaaatta ttgataacca tttaaccttc ctttctatgc agatataatc tattataaca
      901 taaatcgctt acaaatcgtg tgggcataaa aacacagtct gcaaaaaaag ccctgatagg
      961 catgcctatt agagcctcga aaagaaaaat attgaatcaa tctggtcgta cctcttggat
     1021 cggtttgaca cgaccgccga ttcttttagc aaaagcttcg gattcttttt tgtctttgaa
     1081 aatgagcaga ttgtctaagt ttttttcccg agtgcgacag ccagttttat cgatgtaacc
     1141 gtgcattact ttaacgacat acatggggat cacctgcttt tttcttttca ttatacgaac
     1201 tactcgacac aatacaagaa aaatgcttag acggtcttta ttaagaattt acatcatcca
     1261 aagaagcgta cgcttggaat aactgttcta actccggatt gactttgctc agcttcacta
     1321 atcgttgcga atcagaaagt aaaaaacagt gtttactact gccagtagtt tttaattttt
     1381 tgtcttcagt tcccacaatt tcgtagctaa aatccaaccg tgttcccgta tacttttgga
     1441 tagttgggtg gatgctcact ttttctccgt aatggatcat ttctttatag ctgcaattta
     1501 cttccagaac ggggatgatg atcccagatt cttcgatttt tttataggga aaccctagat
     1561 gtaccaataa ggctacccga gcctcttcaa accagcggat ataattgctg tgatgaataa
     1621 tccccatttg atctgtttca taataaaaag gttctcgcac ataacctgta aatttctcca
     1681 tgactcatgc ctcgttttcc attgattttt tacaaaaata attcatccac ttcggaagtg
     1741 cttcgctgat ttgtgtcggc aaaacaatat attgttcttt tgccagctgg tctccaatga
     1801 aactatgaag ataaacagct gctgcaatcg tttggtcatt ttgaggaaac tgggctaaaa
     1861 atcctgtgat catcccagct aaagtgtcac ccatgccgcc tgttgccata gcagcagaac
     1921 ctaaaggatt ggtgtagaag tgctggtgac cataaatttt tgtctcatga cttttcaaaa
     1981 cgagcacagc accgatttcc tgttgcttct ttttgttttc tttatcccgt tgttcttgta
     2041 tcggtagaga actcaaccgt tgccactcca tttgatgagg tgtaagtaca gtttgttcgg
     2101 gatagggtag caaaagatga ttagcaacaa gtaaacttaa agcagagcca tcaatcacca
     2161 gccattgttc ttttgattgg ttttctagta cttgtttgaa acgttccaaa ctcttagaag
     2221 aagtacccaa tccgggacca atcaagagta catctgcttg ctttattacg gaaagaaact
     2281 ggtcagtatc cgtccaatct acaatcattg cttctggcag atgactgtga agagcactcc
     2341 gatttttttc atcagttact acagtcgtga gacccgctcc actgtgtacg gcagctaaag
     2401 cactcataat gattgctccg ccatattgtt cattgccgcc aatcaaaacg atacgtccaa
     2461 atgttccttt atgtgaaatc tttggacgag gtgtgatgac tcttttcact agttgttcgt
     2521 ttatcagcat cgaaaaacct ccttttactc attatagcgt atattttttt tagagaaaaa
     2581 cagataagaa aaggaattgt cagatttttt gaactatttt tttctgtaat ttgtggtatc
     2641 atgaacacga agacttaaat aagtggagga ttaactttat gacaattgat tggcaaaaag
     2701 aagtagaagc acgtaaagaa gacttgcttg aagacttgaa aaatctttta cgtgtcaaca
     2761 gcgagcgcga tgattcaaaa gtaacaccag atgcaccatt tggacctgga cctcgcgacg
     2821 cattgaaaca tatgttagct tatggcgaac gtgatggatt taaagtaaaa aatgtcgata
     2881 actatgcagg gcatattgat cttggcgaag gagacgaaac gctagggata tttggacaca
     2941 tggatgtcgt tcctgcagga gatggctggg acacagatcc ttatgaacca gtaatcaagg
     3001 atggaaagat ctttgcacgc ggatcaagcg atgacaaagg tccaagtatg gcagcttact
     3061 atgcgatgaa gatcattaaa gaacttgact tgaaactatc aaaaaaagtt cgcttcgtag
     3121 tcggcagcga tgaagaaagc ggctggggcg atatggctta ttatttcgaa catgaagaag
     3181 aaccagattt tggtttctca ccagatgctg aattcccaat catcaatggt gaaaaaggaa
     3241 atgtttcttt agctttacgc ttcaaaggcg acaatgcagg agattatgtc ttgaaatctt
     3301 ttgtttccgg acttcgcgaa aatatggtgc caggaacagc aactgcagca cttcaagtac
     3361 caagtgcaga tgcagctatc gcgatggaag aagcatttta ccaattcatc gaagcaaatc
     3421 cagtaagcgg aacgattgaa gcggacaata cgtatgtaaa aatcgaatta gttggtaaag
     3481 gcgcacatgg tgcaagccca caatctggta tcaatgcagg ttctttcttg gcattgttct
     3541 tagataacta tgaattccta ggatctgcta aacaatttat ccatgtagca gctgcttatg
     3601 tccatgaaga tttttatgga gaaaaactag gagtcgctta tgaagatgaa aaaatgggca
     3661 aattgacaat gaatgctgga ctatttgctt ttgaagaaaa tggtacagag gaagcgaact
     3721 tcatcaatat gaatttccgt tttccaaaag gtgtaacagt agacggattg caaagtgaca
     3781 tcgaacaaac agtggggcaa gaaggcgcaa cagttactcg aggtgctcgc gtaatggaac
     3841 cacattacgt accaatggat gatccattgg tggctacatt attgcaagtc tatgaagacc
     3901 acactggaga aaaaggctac gaacaaatca tcggtggcgg aacttacgga cgtttgttga
     3961 aacgtggcgt tgcttatgga gcgatgttcc caggatatac tgatacaatg catcaagcaa
     4021 acgaatttat gagtcttgat gacttgttca gagcaacagc aatctatgca gatgccatct
     4081 atcgtttggc gaaataaaaa tactaaaaaa
//
LOCUS       DAXQKX010000117         4022 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.124, whole genome shotgun sequence.
ACCESSION   DAXQKX010000117 DAXQKX010000000
VERSION     DAXQKX010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4022
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.124"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            59..232
                     /locus_tag="ACF3MF_002754"
     CDS             59..232
                     /locus_tag="ACF3MF_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928648.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            872..1345
                     /locus_tag="ACF3MF_002755"
     CDS             872..1345
                     /locus_tag="ACF3MF_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HFE3928649.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1354..1581
                     /locus_tag="ACF3MF_002756"
     CDS             1354..1581
                     /locus_tag="ACF3MF_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3928650.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            2217..2588
                     /locus_tag="ACF3MF_002757"
     CDS             2217..2588
                     /locus_tag="ACF3MF_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928651.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(2844..3086)
                     /locus_tag="ACF3MF_002758"
     CDS             complement(2844..3086)
                     /locus_tag="ACF3MF_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFE3928652.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(3118..4020)
                     /locus_tag="ACF3MF_002759"
     CDS             complement(3118..4020)
                     /locus_tag="ACF3MF_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFE3928653.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
BASE COUNT         1160 a          715 c          633 g         1514 t
ORIGIN      
        1 tttcttattc acttctttgg tttatactat tcttataaat aaaaatgagg tatgtcctat
       61 gatgaaaaga ttgtactatt cattgatcat aacgattggc tatttgattg tatcaaatct
      121 aggaaatatg gtatttggta tcagtaaaga attcagttgg actactacat tatgggaatc
      181 tctattcttt ttcatcttcg tatttttgtt acaaaattat cgaaaaaaat aaacatgtgc
      241 catctatctg ttggcacatg ttttaggatt tatggtactt tttattcggc aatccatttt
      301 atttttctac ttcttcttaa tacctctaac acttttgatt tataaactaa tccaatgcat
      361 ctacttgcgc ttattaagct atttcagcta gatagtacca ccccatgcgt caatgcttga
      421 ttttcctttt gtataacatt gtataagcaa taaaggacaa ataagtggtg attacaccaa
      481 accattgaat aagaaaaatt ctgatacgta aataaacatg aacttgaaaa aattaatgaa
      541 tcggttagct actacgtagt tgtctttttt ctcatacagt tctgttaact tacacttctc
      601 ttcgctagat aataaaaaat cctccaactg tattgtccaa tataatccca ggcatctaaa
      661 ctagcattat agaagagaca cacatagaat ctaaaataac tggttttaaa tgtttcttac
      721 aatcaaaaaa agctgttaaa tgcactccac accttcatac tctatcattt tttataaacg
      781 atatattttt attgtttttc gataaaaaat agttgtttta caataattat tctgctatat
      841 tttagctatc aaagataaaa gagggataaa aatgaaattt aaaacattgc tattaaaatt
      901 tgtcgtttta ggtataagtg ccgtatttat tttgttcggc gtactttttt atactcagat
      961 cgctacaagc gaaaaaggat tcaattttga ttggcagacc acattatttg tttctgtcat
     1021 ttactttgcc cttctcctag ggatcgttat tgcttatttc ttattgaaac tattgaaaaa
     1081 aatcgaagat aaccaagctt tttccactca aagcttaaac atactaaaaa aaatcgaacg
     1141 aaccattttg tttattggtt tcgccttttt tggcttactt cctaaattta tgaaagtagc
     1201 ggatttagac gatgctccag gtttgatgtt ggtaggaatc gctgtcgtat tcattccttt
     1261 tgcagtatac acattaacaa gcgtgctgga aaaactgctt gaacatgcga ttttacttaa
     1321 gacagatcat gatttgacag tgtgaggtgc gacatggcaa ttatcgttaa tttagatgta
     1381 gtattagctc aaaaaaaaat gagtgtgact gaattgagtg agaaagtggg cattacgatg
     1441 gcaaacatct ctattctaaa aaatggaaaa gcaaaagcca tccgtttttc cactctcgaa
     1501 aaaatctgcc aagttttgga gtgtcaacca ggtgatttgt tgacctataa aaatgactcg
     1561 aatactatac cagaagaata aaataaagta gaacaaacag taaataaaaa ataatctgaa
     1621 tgatagatgt gtgagacttt tagaagttat ttacgtctat tattcagatt ttttatttcg
     1681 attgaatacc gttttatcta taaataagat atgtactgac tcatacaaag ggggcctttt
     1741 cttctccatg tactatcact tttcctgata caactggttt cctgttacgt tgtagttgga
     1801 tctgctttta gtataatact ttattcattc caccagactg atagcagttt gagcagtcta
     1861 aataatcatg tagtattaca ggccattctg tttcatacct tgaagtgctt aaaacttcag
     1921 ctaatggccc attgtgttaa ctcttactcc attctttttt agtaagctcc catatatact
     1981 gtaaagcctt ctatatatta tgtcatgttg ctttttaaca tttactatgt agttttgata
     2041 aaatgatttg aataacagtg atggacaatt cttttttatt tttaacatta ttttgataat
     2101 aatgattatt tatttaaaaa tacattagat aacatttgtt acgacacgaa aaagcttcac
     2161 aaacaaatat cgttatttta aaatgagggc gaactcacac aattaggagg aatagtatgc
     2221 catttattgt ttactttttt ctttcattac tcgtgatcta tattccatta ccaacatttt
     2281 tcctgctcgt caatcgtcta gcagagcaac atgatacgat tgctgctctt acgaaacttt
     2341 gtttacttct atttgtttgt ctagattact ttacgagcta ttattggcta aaacagacaa
     2401 gagtaaaaaa gagatattat ttcttccttg tctttttcaa tctctttgag tttctgatcc
     2461 attgcttttt acttcatcag tatcatacga tccatttgtg gatcatctgg gttttcaaag
     2521 tggtcgtatt attttgtatg ttcacctttc ctatctcaag aaaatttagg gaggcattgt
     2581 tttattaaag aagcttctct gtatcaataa agacacattt aaggaaaaac ttttaaaaat
     2641 ctaattggga atttgcccgc ataaataaga ggctgtgaca aaagtcttgt cacagcctct
     2701 tattccgtat aaacagtgtt caaaagcttg catcttcgat aatatgccca accaaatgaa
     2761 aaatatgaga agctattttt gtttggctgt tcttattact tgatgaagaa cagctttttc
     2821 acgacctctt tttaaaagtc tttttacagt tttcgagcaa agaatgatac gattagtact
     2881 aaaatgatgg caccaatcaa tgatggcacg attgccattc ctgcaatact tggtccccaa
     2941 gaacctaata atgcttgacc aagtgctgat ccaactaaac ctgctacgac atttgcaata
     3001 atccccatcg aagaaccttt attcgtgatt gctcctgcaa ttgctccgat aattcctccg
     3061 acgataagtg accaaataaa tcccatgttt cgttcctcct aatgttttac ttccttatta
     3121 ctgaacccgt ggttctgtat tttcttttac tttttgtgcg ccgcttccag ctgctgattt
     3181 tactttatct gtttgattcg aagcaaattc accggttttt ttcgctgcgt cagttacttt
     3241 gtcttgcacc gtttcttgat ctttttcaaa ttcttctttt gttttgatgt ccactacgtt
     3301 agcgttgact tcgatcactt ctaaatgtgt catatttttt acttctttgc cgattacttc
     3361 ttgcatttct tcaaagattt tttcgatatc tttgccatat tccacaatga catccatatc
     3421 aactgctact tgttttttac cgacttctgt ttcgatccca gccgttacat tatctgtatt
     3481 cacaagtttt cctgccacat tagagaagaa accaccgttt gcagataata aaccgtctac
     3541 ttgttcaatt gcgattccga tgattttttg cacaacttta tcttcataat tcagctcacc
     3601 gcgcattgaa tcttcctgtt cagaatcatg ctttccttgg ttatttgtat gatcagaacc
     3661 aagttttcct tgtccgtttg tgtggtcaga actaagtttt tcttgtgctt tcgcatggtc
     3721 agaaggatgt ttttgctctt ccacaggttt agaaggatcg attgcatcat gttgttctgg
     3781 aactttagat tctggagttc ctggatgatg aggtgcatgc ttttctgcat catgtttctt
     3841 ctcttctact ccttgttgaa cgttagggac tactggatct ggatgtgcag atactggtgc
     3901 tgttttgttc ttttcatcgt tcacaccatt tgattggttt ggtgtcgttg ggtctggatg
     3961 tgcagacact ggtttttggt tgttcatttt attgttatta tttttgttat tgttattcat
     4021 gg
//
LOCUS       DAXQKX010000118         3961 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.125, whole genome shotgun sequence.
ACCESSION   DAXQKX010000118 DAXQKX010000000
VERSION     DAXQKX010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3961
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.125"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..884
                     /locus_tag="ACF3MF_002760"
     CDS             <1..884
                     /locus_tag="ACF3MF_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HFE3928654.1"
                     /translation="ISVPVALFSFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTY
                     NDYFQIGMIGMIVSLVVVLTVANISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVL
                     GVVLLDLQIILGFILAGIWALLFTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMT
                     LAMFNNSAAYASPYFSAIFGDWIPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILA
                     VVLAVNPTMSPAFLFPLFAITTIAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGW
                     IIGAILCLITFLLYGNA"
     gene            932..3061
                     /locus_tag="ACF3MF_002761"
     CDS             932..3061
                     /locus_tag="ACF3MF_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HFE3928655.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKNLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKAIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPHTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            3036..3725
                     /locus_tag="ACF3MF_002762"
     CDS             3036..3725
                     /locus_tag="ACF3MF_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928656.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKEIE
                     KRCTEYDLDYK"
BASE COUNT         1252 a          712 c          886 g         1111 t
ORIGIN      
        1 gtatttcagt accggttgca ctgttctcat ttatgggctc gattatggct ggaatctttg
       61 ctaatatcgt caatttcaaa caatatcaaa cgatttatgc tggtttcaat ccagcggctg
      121 aaagctatac ttataatgac tatttccaaa ttggtatgat tgggatgatt gtaagcttag
      181 ttgtggtact aacggtcgct aatatatcaa tgaacaaaaa gaaacgctat gcaatggcag
      241 caaacgtacc agctgaaggt ggcgacgcac caatgatctc atggttagcc gtattattac
      301 cagttttagg ggtcgttctt ttagatcttc aaatcatctt aggttttatt ctagcaggta
      361 tctgggcatt gctgtttact ggaaaattgc gcggaggtta taaagaaatc tgtcgtcagt
      421 ttgcgaaatt atttacagat ggcgcagtcg atgttgcacc aatggttggt ttcttgatga
      481 ccttagcgat gttcaataat tcagctgcgt atgcttctcc ttatttttca gctatttttg
      541 gagattggat accgcaatca ccattagtct tggcaatcgt atttgctata ttgacaccac
      601 taggattttt ccgcggtcca atgaatctag tcggttcagg ctcagctatt ttagctgtcg
      661 tgttagctgt taatccaacg atgtcgccag cctttttgtt cccgttattt gcaattacaa
      721 cgattgctcc tcagcattta gatattacac aatcttgggt tgcttgggga ttaggttata
      781 caaaagtaac ttctcgagaa tatatgaaga aatccatccc aactggttgg atcatcggtg
      841 cgatcttatg cctgatcacg ttcttattgt acgggaacgc ctagtaaaca aaacgtcgat
      901 aaaaacgatt agataaatgg aggaaaagaa aatgaaacgt tttgtgcgaa tgggaattga
      961 tgttggcggt acacatacga aagcagtcgc aatcgataat gcgacgcacg aaatcatcgg
     1021 aaaatcttca gtgaaaacaa cccacgatga tgtccgtgga gtagctgcag gtgtcgttca
     1081 gtcttttcaa aattgtttgc gggaaaataa tatcagtcca gaagatgttg tgtttgttgc
     1141 acattctacc acacaagcga ctaatgcact gattgaagga gacgtagcaa aagtcggcgt
     1201 aatcgggatg gcaaaaggtg gattagaagg ttttttagca aaacgacaaa ctagattgaa
     1261 cgatatcgat ttagggaata agaaaaaaat agagattgtc aatgcattct tacctgtcaa
     1321 aaacttaaat gtagaccgtg tttcagaaac gatttcttct ttagaaagag aaagagcgga
     1381 ggtcttggtt tcttctatgg catttggagt agataatggg gaaccagaac gagttgttta
     1441 tgaagcagca tctgtgaaag cgatccctac aacgatggct tctgacatca caaaattata
     1501 tggattgaca agaagaactc ggacagcagc aatcaacgca tctattttac caaaaatgct
     1561 agatacggca acctcgacag aagactccgt acgagaagca ggggtcaatg tttctttgat
     1621 gattatgcgc ggagacggcg gagtaatgga aatcaatgaa atgaaaaaac gacctgtttt
     1681 aaccatgctt tccggtcctg ctgcatcagt catgggctct ttgatgtact tgagagcgtc
     1741 taatggtgtt tattttgaag taggcggaac aacaaccaat atcggggtca ttaaaaatgg
     1801 acgtccagca atcgattatt caattgtagg tggccaccca acatatatct cttcattaga
     1861 tgttcgggtt ctaggtgtgg caggcggttc gatggtacgg gctaatcagt caggaatcat
     1921 cgatgtcggt ccacgttctg cacatattgc cggtctagat tatgcagtat ttacggagac
     1981 agaaaaaatc aaaggtccta aggttgaatt tttctctcct aaagaaggag accctgctga
     2041 ttacgtcaag gtagtgatgg aagacggaga agaagtgact attacaaata catgtgcagc
     2101 caatgttctt ggattagtgc aagaagaaca tttttcttat ggaaatgtcc catctgcacg
     2161 aaaagccata caggcattag cagactattg tcatacgacg gttgaagaca tcgcagagca
     2221 gatcatggaa aaatcctatg ctaagattga accggtgatt ttagaattgg cagacaagta
     2281 tcacttggag aaagatcaga tttctcttgt aggtgtaggg ggcggcgctg cctcattgat
     2341 tacttacttt agtaataaaa tgggtgtgaa atattcgatt cctgaaaacg ccgaagtgat
     2401 ttcttctatt ggtgtagcac ttgcaatggt ccgagatgtt gtagaacgta tcatcccttc
     2461 gccaagtaaa gaagatatac gatcgttgaa aaatgaagcg atgaataaag cgattgaatc
     2521 aggcgctaca ccagaatcga tcgaagtcca cgtagaaatc gatccacata cttcaaaagt
     2581 aacggctatc gctactggtt ctacggaagt gaaagcaacc gatctaacca aggagatcac
     2641 aacagaagaa gcactagagc ttgctgcaga ggatatgcga ttaaataaaa atgaagtttg
     2701 cttattggaa aatacacctt tcttttatgt atgcggcgaa cagaatcgtt caaaaaatgc
     2761 tggaagtctt cggatcatcg atcaaaaagg atttatcaag gtccaacgtg gacatgcttc
     2821 atgtatgaaa acaactgcag ccaattatat gacagctgtc gaacaacttt gggaagatat
     2881 ggcagtttat caaactgaat tgattgcccg accagaattt tatctctgct taggagcaag
     2941 agtctctgat tttacagcga cggatctgga acaactacag cttttgatgg atctggaagt
     3001 atctactatg gaaccggagg aagaagtgat cgtcgttgcc ggaaatatca aacaaacata
     3061 agttagaaga gttactaaac gaattacaac agatccccga agaaatttgg ggattctacc
     3121 agtttcggcg agatttattt tggaaaaaga ttcctttgtc caagcagaaa attcttatac
     3181 aacaatcaat cgattgtggt atcgaaacgg catgtagcat caaaaaaaag tacccttttg
     3241 ccgatgtagg agaaatctgt gaacaaatgg ctgttccaat cgtttcctgt gaatcagagc
     3301 aaataaacga acgaatcact tttgcaactt atgcagaaga tgaagggatc cgattgatga
     3361 cggagccgtt agaaaaatta aaatgttcag gactagcttc gatctctaaa gaaacagcgc
     3421 aagctttgat tattggacat gaactatttc accacatcga agcttctgtt aagggaattt
     3481 atacgcaaag cgaaaaaatt gtgctgtggc ggttgccttt ttatacacat caatcaaaca
     3541 ttcgtgcatt gagcgagata gcagcgatga gtttttcaaa agagatgaat caaagcgatt
     3601 tttcgcctta tgtattagag gcagtcttac tttggccata taatgaaatt cgtagccaag
     3661 ggatcttaga agaaataaaa gaaatagaaa aaagatgtac ggagtatgat ttagattaca
     3721 aataaagaga ctgtgacaaa agtcgtgtca cagtcctttt tttccgaata aacggtgttc
     3781 tcctgtcaac tcctcggtca caagtcaaaa tattcaacaa acatgagaag ctgttttttg
     3841 aaattgttcc ttgtgactcg gagatgaacg gcaggctcac gacctcttgg aaaaaggtgt
     3901 tcaaaagctt gcatctgcgg taataagaac agccaagtta aaaacataag aagctatttt
     3961 t
//
LOCUS       DAXQKX010000119         3785 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.126, whole genome shotgun sequence.
ACCESSION   DAXQKX010000119 DAXQKX010000000
VERSION     DAXQKX010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3785)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3785)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3785
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.126"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            1..168
                     /locus_tag="ACF3MF_002763"
                     /pseudo
     CDS             1..168
                     /locus_tag="ACF3MF_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
     gene            406..642
                     /locus_tag="ACF3MF_002764"
     CDS             406..642
                     /locus_tag="ACF3MF_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928657.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            649..2601
                     /locus_tag="ACF3MF_002765"
     CDS             649..2601
                     /locus_tag="ACF3MF_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HFE3928658.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2673..3170)
                     /gene="dfrG"
                     /locus_tag="ACF3MF_002766"
     CDS             complement(2673..3170)
                     /gene="dfrG"
                     /locus_tag="ACF3MF_002766"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HFE3928659.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            3445..3785
                     /locus_tag="ACF3MF_002767"
                     /pseudo
     CDS             3445..3785
                     /locus_tag="ACF3MF_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1344 a          614 c          655 g         1172 t
ORIGIN      
        1 tctctgttcc ctctttatca tggaagtgca aaaagtaata tagggattga taaccttata
       61 gaagttatta ctaataaatt ttattcatca acacatcgag gtccgtctga actttgcgga
      121 aatgttttca aaattgaata tacaaaaaaa agacaacgtc ttgcatatta agtagttcag
      181 ttttggagta caaaaagtga aaatgtaaac ctaaatgagt atcaaattgc aactgaattt
      241 gatactcgtt ttttattgtt aaatcaacgt ttgttgttaa tttacaccac aaaatgtaag
      301 ttaaaatgta tataaaaatg cgaacgtgaa ataattattg taggaatgca aattggtgtg
      361 ttaaaatggt tacaatttac taagcaaaaa ggggtgcatt ttcctatgca atttcttgag
      421 ccaaaaaata agaacgctaa gtctgtggat tgggaaatat cagagcaagt aagggtgata
      481 gttaagcaat acgctgaata tgcagagcgt actgaaagcg aagcagtgga tgaattctta
      541 ttgaacattt tagacgataa gaagtttatt gaatggattg ccaacaagcg aagtaataag
      601 cggattgttg aaaaaatggg tatcaaagat agagtgggtt gatagacaat gaccaagctt
      661 aaaagattag ccacgaagga agatgaaatt gtagatgtta aaattccgat ttcaaacgaa
      721 gaattaaaag atagggctaa acaatatgat ttattaactc caaaacgatt tgcaacaagg
      781 tataacaaaa tgttgttctt gccaacgtct tttaaatgga acggttctga atatcccatt
      841 caatataatt actgcatcaa tccgttttgt tgtaattttg ggaaagaaca gcacaaattc
      901 aaagatgtaa aagggaaacc aagtcgatat aaaatgactg gtagttccaa agataaaggt
      961 cataaaggta tgtactgcaa tgacaatcct attggcagag gtgtatcgca aaactgtaca
     1021 gtaacccctt tatctaattg gtctgttgtt gaagaaatta aacgccttat agaaatcaat
     1081 agcatccaag atgttgagcc agattatcaa tttcataaag aaggctgctc ggaagaagaa
     1141 tcaaccccat tcaatgagcc gaagcaattt tacaaaaggg ggaaaagtag gggcaaatct
     1201 caacgctatc aatgtaaggc gtgtaagaag ttcactaatg ttctaccaaa aagagaagaa
     1261 accactactt atcaccaaca aaagaacacc attcttccaa tgttcgctaa gatggttgtt
     1321 ggaagggttt cagtcagtcg tacttgtgat attttaggaa ttggagttgg aacctactat
     1381 cataagctgg agtggctgta taggcgttgt ttggagtttt tagaacgata tgagacacaa
     1441 ccccttcaaa caaagaaatt taacgagatg tggcttaata cggacaagat gcactactac
     1501 ctaaataacg tccgtaagaa aggacaaggt tcaaagaaat atacggggtt tgaagacctt
     1561 aatatgcaaa cgtatatagt tgtatctgct gaggtcttat caagatatgt gttccgttct
     1621 gatgttgcct atgattggaa tatttcaatg gatgaattaa atgaagatac aagaaaattc
     1681 aaagaagacc atctcaatac ttttagtcgt aaaaatgata ggttagattg gtcttattat
     1741 ccacaagaac catccgctaa cgatagcgaa aataggaatg cttatcttca cgaattaggg
     1801 aaaattacta ataggagtag atttgtcgat ggtttaaatg ttgatgctcc ttatactaca
     1861 actgctcact attggttaat taaacaaatg gttaatgccg acgaatggcg aatgattagt
     1921 gatgatgact tctctattag aaacgccttt tatagagtat tcacgaaaga attaaggttg
     1981 agcgatgcac atcattttat ttgccaagtt aacaagacga aaagcagaaa acaatgctta
     2041 aaagaattcg gacaagcaaa agcagaactg ctcgattggg gagatatcag aggattcaaa
     2101 acaaagtttc tacggacttt ggcatctcat tatctaactg aattactaac aagtcatcaa
     2161 ttccacgaag aggctattag taaagatgga gaaagatatc gcaaatatgc cgataaccct
     2221 atcaaacatc cattagccac taaggataaa ggattttatt cagttgattg tagaacggat
     2281 ttatctgctc tggaaccaaa cgaaatcgca aagatgctat taaatgttaa tgaccattcg
     2341 accaatagct ttattcaaca gataagacgt tatatatcat ctcttgaaag accattaaca
     2401 acagctcgtg gtgataagaa gagctatatt tacgctaact tcaatccgaa gtatgctcaa
     2461 tttgcgatta caattctaag aacttactac aacttttgtc gcccttttaa atcagcggat
     2521 aaaaaggttt tgacacctgc tcaaagatta gggattacag ataaacaatt tgattggaaa
     2581 gatataattt atttcaaatg acaaaaagag cttggagtaa tcccaagctc ttgtgcttta
     2641 tctttactgt tcttcttcaa ttaacgcacc cgttaactca ataagttttt tctttcatat
     2701 acatgaaaat agtagttata cggattttta tcattcttta tccctttttg ggcaaatacc
     2761 tcattccatt cctcataatt cacttctgga aaaaaagtat ctccttcgaa ttcatgatgt
     2821 atttttgtga tgtacatttt ctcaacataa gggaaaaaca aattataaat ctgttctcct
     2881 ccgaaaataa aaatttcttc ttcgttttta cataactcaa aaacatcttc tattgaatga
     2941 acaatttcac aaccattaaa ggtaaacccc ttatctctcg tcagaataat atttcttctg
     3001 tcaggtaagg ctcttccgat tgattcaagg ttcttcctac ctaatattat cggatgtccc
     3061 tttgtagtat ttttaacata ttcccagtcc ttgggaatcc tccaaggaat gtcattctct
     3121 ttgccaatca ctctattctt atccatcgca gcaatcaaag aaactttcat ttataacaca
     3181 gcctttttaa ctaatttacc atctaatttc ttatttctat caaaaaacct tttctcatta
     3241 tcctgcccgt tagttgaata agcaattttt tctataagtt atattatcat aataccacaa
     3301 aatcacaaat tttcattcaa ttatcatttt caattgcatt ttataaatca ttttgtatgt
     3361 aatttggtat gtaagttaaa atgaaaaaag tagtccattt tgaagtacat tttgtcattt
     3421 tgtactccaa aactgaacta cttacttgca tatatacgcc tttatagtgg agtactacat
     3481 ttacgagatt cggttagagt atcagaaaaa gaaaaaataa aagttacaga aatgtatact
     3541 tcaataaatg gtgaattatg taagattgat agagcttatt ctggagaaat tgttattttg
     3601 caaaatgagt ttttgaagtt aaatagtgtt cttggagata caaaactatt gccacagaga
     3661 aaaaagattg aaaatccgca ccctctacta caaacaactg ttgaaccgag taaacctgaa
     3721 cagagagaaa tgttgcttga tgcccttttg gaaatctcag atagtgatcc gcttctacga
     3781 tatta
//
LOCUS       DAXQKX010000120         3305 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.127, whole genome shotgun sequence.
ACCESSION   DAXQKX010000120 DAXQKX010000000
VERSION     DAXQKX010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3305
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.127"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(162..2159)
                     /gene="tkt"
                     /locus_tag="ACF3MF_002768"
     CDS             complement(162..2159)
                     /gene="tkt"
                     /locus_tag="ACF3MF_002768"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HFE3928660.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2261..2512)
                     /locus_tag="ACF3MF_002769"
     CDS             complement(2261..2512)
                     /locus_tag="ACF3MF_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HFE3928661.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2659..3282
                     /gene="lexA"
                     /locus_tag="ACF3MF_002770"
     CDS             2659..3282
                     /gene="lexA"
                     /locus_tag="ACF3MF_002770"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HFE3928662.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
BASE COUNT          906 a          727 c          615 g         1057 t
ORIGIN      
        1 ctcaagaaac acaaactaat ccgaagaatt ctttgttttg tcatttaaat gtaacatagc
       61 cgaaaacgaa aagtaatatt gatttattct tctaacacat aaagaacagc tgtctccaac
      121 ttgcagacag ctgttcttat cagtcaaaca attgcttgga tctatgatag ttgattgtac
      181 gtattcacga cattttctac tgtaaatcca aattcttcta aaattttagt gccaggggca
      241 gatgcaccga aatgatcgat tgtaatcgtt gcgccctctg ttcctacgta gcgttcccat
      301 ccaaatgatg cagcagcttc gatagccaca cgtttcttca ctgatttagg aagtacactt
      361 tctttatatt cagaagattg tttttcaaag aggtcaaagc ttggcataga aacaacagaa
      421 acatctttgc ctttttcagc caattctttt tgagctttca cagccaaatc aacttcagaa
      481 cctgttgcaa tcaaaatacc ttctggtgtt tctccttgtg atggagaaag aacatacgcg
      541 ccttttttca ccatttcatc tgctacttct tttgtagaag gcaatactgg aaggttttga
      601 cgactcaata caaggatagt aggcgcatct gttgtctcca tcgctacttt ccaagcagca
      661 cgtgtttcat ttccgtctgc cggacgaatc acttgaacac caggcatgca gcgaacagat
      721 gctagttgtt caatcggttc gtgcgttggt ccgtcttctc cgacagcaac cgagtcatgt
      781 gttaagacgt aaacaacagg agtatgttgg attgctgcta aacgaactgc tggtcttaga
      841 taatcgacaa agacaaagaa tgttccaccg tagatacgag ttccgccatg aagttggata
      901 ccattcatag ccgaagccat tgcaaattcg cggacaccga accagatgtt gcgtccttca
      961 taatgttcag gagtgaaatc tttatctgca gccaccattg tattattgga acctgacaag
     1021 tccgctgaac caccccagaa gcttggtata gctttcgata attcttggat gacttcttta
     1081 cttgaaacac ggcttgcttg actgcttcca acttcataag ttggcaattc tgcatcccag
     1141 ttttctggta gtttgccatc aaaagcatct tcaaattgtt gtgctaattc aggataagct
     1201 tttttataat tggcaaacat ttcattccat gcatcttcag ctttttgtcc ttcttctatc
     1261 atcgtttgat ggaagcgggc agctacttct tctggaacag tgaaatctgg atactcccaa
     1321 ccataaactt ctttagccat cttgatgcca tcttcaccaa gaggagcacc atgaacagca
     1381 gatgttcctt ctttaggagc accatagccg atgactgttt ttacttcgat caatgttggt
     1441 ttgtctgttt cagcttttgc ttcttcaatc gctttagaga ttgcttctag gtcatttccg
     1501 tctttcacta agatatgttg ccagccatat gcttcatagc gagcaccaac gttttctgtg
     1561 aaagcttttg aagttggacc gtctagtgaa atatcgtttg aatcgtataa aacgatcaat
     1621 ttccctagtt tcatatgacc tgccatcgaa cttgcttctt gagatacccc ttccatcaag
     1681 tctccgtcac cgcatattgc atacgtatag tgatccatca cattaaagtt ttctttgtta
     1741 tacgttgctg caaggtgcgc ttctgccatt gccataccga cagccattgc aatcccttgt
     1801 cctaatggcc ctgtagtggc ttctacacca tctgtatgat gtacttcagg atgtcctggt
     1861 gttttagaat cccattgacg gaattgtttc aaatcatcga ttgtcacttg atagccagct
     1921 aaatgaagca agctatacaa cattgctgac ccatgtcctg ccgaaagaac gaaacggtcg
     1981 cggtcagccc agttttttga tgtcgttgga tttactttca ggtgttttgt ccataacgca
     2041 tatgccatag gtgctgcgcc catcggcaat ccaggatgtc ctgagtttgc tttttggact
     2101 gcttcaatac ttaatgtacg aattgtgtta acgccaagtt ggtcaatttt gtcaaacaaa
     2161 ataacccctc ctattaattt aggttttttt tacctttatt tcttacactt tcattctata
     2221 agatgtcaca cgaaaaagca atctttttca gtatttttta ctaaaagttg tcatttcggt
     2281 tgtgtaagcc ttttttcttt tggatttctt ttaatttttc cggggtcacg tcattgccct
     2341 caggatcgac gactttcatt ccttcgatat gatgacgcat accggaacga aaagcttcca
     2401 aatactcttt gcgcaagttg atttgttctt gttcttcggc ttttgagaga ccattttcct
     2461 tctttttacg tgcaagttca ttgatccgct ctattttttc aggtgacagc atgctcagcc
     2521 ctccttttac tctccttcat attatataaa aactgaaaaa aaaacaacta gataaactaa
     2581 ataaaatacg aacattcgtt tgatttagcg ctttttatat ggtactattt atttatcaag
     2641 tgaaagaagg tgtaccttgt ggcccgacaa actgaatcaa gacaaatcga agtcttacga
     2701 tatatccatg aacaagtaac ccaaaaagga tacccgccga ctgtccgtga aatcggggaa
     2761 gctgttcagc tttcttctac ttctactgtt cacggtcatc ttgcacggct tgaaaaaaaa
     2821 gggtttatcc aaagagatcc gacgaaacct cgtgcaatcg agttgacaaa acaaggttta
     2881 gaaaagattg ggattcgtcc aacaactatt ccagtacttg gcgtcgtaac agctggagaa
     2941 cccattttag cagtagagga tgcttcagac ttctttccaa tccctcctaa tctttcttcc
     3001 gaagaaggca gtctctttat gctgacaatt cgtggagata gtatgatcaa tgctgggata
     3061 ttggatggtg acaacgtgat cgttcggaag caagaaactg ctcaaaatgg cgatattgtc
     3121 attgcaatga ctgccgagga cgaagcgact tgcaaacgat tctataaaga aaaaaacttt
     3181 ttccgtctgc agcctgaaaa cgacttgctc gaaccaatca tcttagatca agtatctata
     3241 ttaggacgag tagtaggact ttatcgtagt catatctatt aattgctact aattaaaaga
     3301 aaact
//
LOCUS       DAXQKX010000121         3280 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.131, whole genome shotgun sequence.
ACCESSION   DAXQKX010000121 DAXQKX010000000
VERSION     DAXQKX010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3280
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.131"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..584
                     /locus_tag="ACF3MF_002771"
     CDS             <1..584
                     /locus_tag="ACF3MF_002771"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFE3928663.1"
                     /translation="AFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIELS
                     KKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMAN
                     SGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHVL
                     EGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            complement(661..1836)
                     /locus_tag="ACF3MF_002772"
     CDS             complement(661..1836)
                     /locus_tag="ACF3MF_002772"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HFE3928664.1"
                     /translation="MIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADMDFLSPG
                     GVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVLTSLAAA
                     VQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDMEKKIEEN
                     NVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHTFTSMLT
                     IDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEINTFGLI
                     GTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLDFTAYIS
                     DDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYALETID"
     gene            1918..2298
                     /locus_tag="ACF3MF_002773"
     CDS             1918..2298
                     /locus_tag="ACF3MF_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvfD/Ygs/GSP13 family RNA-binding
                     post-transcriptional regulator"
                     /protein_id="HFE3928665.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            2372..2734
                     /locus_tag="ACF3MF_002774"
     CDS             2372..2734
                     /locus_tag="ACF3MF_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928666.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
BASE COUNT         1112 a          538 c          623 g         1007 t
ORIGIN      
        1 tggcattccc acaactagat ttaaaaagtg aaaaaggacc aaaagctgtt atcaaaacaa
       61 accgtggtga cattactgtt caattattcc ctgaactagc accgaagacg gttcaaaatt
      121 tcattgaact ttccaaaaaa ggttattatg atggcgtgat ttttcaccgc gttattcctg
      181 atttcatgat ccaaggcggc gatccaactg gaacaggaat gggtggcgaa agtatttatg
      241 gcgaaagttt tgaagatgaa ttcagtcgtg aactgttcaa ccttcgcgga gctttatcta
      301 tggcaaattc aggtccaaac acaaacggaa gccaattctt tattgtaaat aacacaaatg
      361 tgccagctaa tatgcttgga caactagaag gtgctggatt cccatcagaa atcattgaag
      421 cgtataaagg tggcggaact ccttggctag atttccgaca tacagtcttt ggacatgtac
      481 tagaagggat ggacacagta gatgaaatcg caaatgtaca acgtggtcca caagaccgac
      541 ctgtacatga tgtagtgatt gaaacaattg aaatttcaga atagtttggt atggtacgga
      601 gtaattatga aaaaggacga aacctagtaa ggtctcgtcc ttttattttg aataaatgat
      661 ttaatcgatt gtctctaaag catacttgat tcgattaagt ccttccagta aagtttcttc
      721 tggacaagca atattcaagc gcatatgccc atgaccggaa ggaccaaacg tgatgccagg
      781 atttaatacg acttttcctt tccgaacaag agtgttctcc aattcttggt cgtctgaaat
      841 ataggcggta aaatctaacc acattaagta agttccttca gggttcatta ttctcacttt
      901 cggaagatac tgttcaaaaa actgattaac tgtttgaaca tttttttcta gataaggaat
      961 cagttggctt aaccattctc cacccgtctc ataagccgct tgggttccaa tcagtccaaa
     1021 agtgttgatt tcgtgctgtt ggttcatcac taaatgtttt tcaaaatcag ctttcatctc
     1081 tggatttttg ataaatacca ttgaattttt gattgcagct agattgaaag tcttggttgc
     1141 ggaagtaaaa gcaactagta gatcatctaa attaggatca atcgttagca tggaagtaaa
     1201 tgtatgatcg aataaagtta aatcttgatg gatctcgtca ctaaacagaa tcacttgatg
     1261 ttttaaacac aattcgctta actgtttcaa ttcttctttg ctccaaacac gccctccagg
     1321 attgtgagga ttgcataaaa tcattgcttt tacattgttt tcttcgattt ttttctccat
     1381 gtcagacaag tccatgatga aatgattatt tttttctagc aaagagcttc gaacgatgtg
     1441 acgttgattt gtttctataa tagaggaaaa tggaggataa actgggtcat gaatcaaaat
     1501 agaatcgcct ggttttgtaa aagtttgtac tgctgcagct aaactggtta acacaccact
     1561 tgtaaaaacg atattttctt tcgtcaactc cacagcatgg tgttggcgtt cccaatgaat
     1621 gatagcctga tatagtttat cagacagagt ggcataacca aagattccat gtttgatgta
     1681 ttcactaaac gctttagcta ccccaccggg agacaagaag tccatatctg ctacccacaa
     1741 aggaagtaag tcatccattt gatatgtctc agcaattgcg tcccatttta cactttctgt
     1801 atcttttctt gaaatctgtt tatcaaattc gatcatctta agacctccag tcattttcgt
     1861 cgcttctttt tttgagctat ttacagtata atgataaatg cgaagagagg gaagtagatg
     1921 acttataaaa ttggacaaat aattgaagga aaagtgacag ggatacagcc ttatggcgca
     1981 ttcgtttctc ttgataacga gacgcaagga cttattcatg tttcagaagt acaatccggt
     2041 tatacgaaaa atatccattc attgttaaaa gtcggacagc cagtaacagt tcagatcatc
     2101 gacattgatg aatattccaa aaaaatcagt ttatctttaa gaacgttaga aaaaacaaat
     2161 ccagctgttc catatcgcag aaaaaggtat ttcacgaata aaaatcgtaa gatcggattt
     2221 accactattg cggagcagtt acctatttgg atagaagaag cattatctga actagaacgg
     2281 aaagaaaata agaaataaaa agtgtgtttt ttctgaaaat gtgctagaat ttttatgtaa
     2341 gccatagaac aagttgatcg aggtggaaat tttggcaagc aaaagagttg ctggtacaat
     2401 tatgttgcat ttggaggatg gtactaaaaa atttttggtc cattcaattg atgacaagtt
     2461 ggaatttgcg ttagcggaac tttctgaagg aaagactggt ttagcgaata tacttaattt
     2521 cttaaaagaa atagttcata tcgatgttag caagattagt ttgatggaat tgacaaatac
     2581 acatattaaa gaggaaaatg ttccgttgtt tgtctttgaa actgaacaaa agaatcaaag
     2641 agaagaatta ggcgaaggat atatttggga agaaccaggt caaatgcgct ctgttcttgg
     2701 aacttacgaa gtagagggag tgcctttctt ctaaaataca gattaagcga acaaagaagt
     2761 ttgaattttt ttcaaacttc tttttttatt gtttggtcca aaaaatacaa tgaaatgttc
     2821 tgctaaagat agttttttag tgcattttat tttcaaaata tgttgaaaac ggttgtataa
     2881 cgaataataa taattgatcg aaaaatcatt tcacaaagta atgcttaatt tatagttgac
     2941 caaggaagaa atacatgata aatttaacag cgttgattct gaagtggatg ttatatcaca
     3001 tttctaaaaa atttaaaaaa tagttattga catgttacta acgacatgat aagataactg
     3061 agtcgttaaa aaagaaccac ttgcgaagct tgattctatc gaaaaaaact tcaaaaaagt
     3121 tcttgacaaa taacaaacga taagttatga taaatgagtt gctgaaagat ttcgaaaaac
     3181 gaaatcgaaa aaaactttta aaaaagagtt gacaatcgct tgtctctctg atatgatata
     3241 aaagttgcta cggcagccaa aaacgaatcg ggaaacactc
//
LOCUS       DAXQKX010000122         3220 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.132, whole genome shotgun sequence.
ACCESSION   DAXQKX010000122 DAXQKX010000000
VERSION     DAXQKX010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3220
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.132"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            81..1253
                     /locus_tag="ACF3MF_002775"
     CDS             81..1253
                     /locus_tag="ACF3MF_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HFE3928667.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFRE
                     AVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRL
                     KSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
     gene            1310..1702
                     /locus_tag="ACF3MF_002776"
     CDS             1310..1702
                     /locus_tag="ACF3MF_002776"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFE3928668.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDDIVYVYDYEKGDK"
     gene            1703..3142
                     /locus_tag="ACF3MF_002777"
                     /note="aph(2'')-Ia"
     CDS             1703..3142
                     /locus_tag="ACF3MF_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HFE3928669.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYDGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTDKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCSHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT         1287 a          378 c          561 g          994 t
ORIGIN      
        1 taaaagtaaa aaggccatat aacagtcctt ttacggtaca atgtttttaa cgacaaaaac
       61 atacccagga ggacttttac atgacccaag tacattttac actgaaaagc gaagagattc
      121 aaagcattat tgaatattct gtaaaggatg acgtttctaa aaatatttta acaacggtat
      181 ttaatcaact aatggaaaat caacgaacag aatatattca agcaaaagaa tatgaacgaa
      241 cagaaaaccg acaaagtcaa cgaaatggct attatgagcg cagctttacg acacgtgtag
      301 gcacgctaga attaaaagta cccagaacac gtgatggcca tttttcaccc acagtgtttg
      361 aacgttatca acgaaacgaa aaagccctca tggcttcaat gttggaaatg tatgtatcag
      421 gcgtttcaac tcgtaaagta tcaaaaattg tggaagaact ttgtggtaaa tccgtctcta
      481 agtccttcgt ttctagctta acagaacagc tagaacctat ggttaacgag tggcagaatc
      541 gtttattatc agaaaaaaat tatccttact taatgaccga tgtactctat ataaaagtac
      601 gagaagaaaa tcgagtactc tcaaaaagct gtcatatagc gattggaata accaaagatg
      661 gcgaccgtga aattatcggc ttcatgattc aaagtggcga aagcgaagag acctggacaa
      721 cattttttga atacctaaaa gaacgcggtt tacaaggtac ggaactcgtt atttctgatg
      781 cgcacaaagg attagtctct gccattagaa aatccttcac caacgtaagt tggcaaagat
      841 gccaagttca cttcctaaga aatatcttta ccaccattcc taaaaaaaat tcaaaatctt
      901 tcagagaagc tgttaaagga atttttaagt tcacagatat taacttagcg cgtgaggcta
      961 aaaatcgatt gattcatgat tatatcgatc aaccaaaata ttcaaaagct tgcgcatcat
     1021 tggatgatgg attcgaagac gcctttcaat ataccgtaca aggaaattcc cacaatcgac
     1081 taaagagtac caatctaatt gaacgactga atcaagaagt acgcagaaga gaaaagatta
     1141 ttcgcatctt ccccaatcaa acatcagcca atcgcttaat tggagccgtt cttatggacc
     1201 tacatgatga atggatttat tcttcaagaa aatacatcaa ttttgataag tagaaatggt
     1261 aaaaacattg tatagcattt tacacaggag tctggacttg actgagttta tggaagaagt
     1321 tttaattgat gataatatgg tttttgatat tgataattta aaaggatttc ttaatgatac
     1381 cagttcattt gggtttatag ctaaagaaaa taataaaatt ataggatttg catattgcta
     1441 tacactttta agacctgatg gaaaaacaat gttttattta cactcaatag gaatgttacc
     1501 taactatcaa gacaaaggtt atggttcaaa attattatct tttattaagg aatattctaa
     1561 agagattggt tgttctgaaa tgtttttaat aactgataaa ggtaatccta gagcttgcca
     1621 tgtatatgaa aaattaggtg gtaaaaatga ttataaagat gatatagtat atgtatatga
     1681 ttatgaaaaa ggtgataaat aaatgaatat agttgaaaat gaaatatgta taagaacttt
     1741 aatagatgat gattttcctt tgatgttaaa atggttaact gatgaaagag tattagaatt
     1801 ttatgatggt agagataaaa aatatacatt agaatcatta aaaaaacatt atacagagcc
     1861 ttgggaagat gaagttttta gagtaattat tgaatataac aatgttccta ttggatatgg
     1921 acaaatatat aaaatgtatg atgagttata tactgattat cattatccaa aaactgatga
     1981 gatagtctat ggtatggatc aatttatagg agagccaaat tattggagta aaggaattgg
     2041 tacaagatat attaaattga tttttgaatt tttgaaaaaa gaaagaaatg ctaatgcagt
     2101 tattttagac cctcataaaa ataatccaag agcaataagg gcataccaaa aatctggttt
     2161 tagaattatt gaagatttgc cagaacatga attacacgag ggcaaaaaag aagattgtta
     2221 tttaatggaa tatagatatg atgataatgc cacaaatgtt aaggcaatga aatatttaat
     2281 tgagcattac tttgataatt tcaaagtaga tagtattgaa ataatcggta gtggttatga
     2341 tagtgtggca tatttagtta ataatgaata catttttaaa acaaaattta gtactgataa
     2401 gaaaaaaggt tatgcaaaag aaaaagcaat atataatttt ttaaatacaa atttagaaac
     2461 taatgtaaaa attcctaata ttgaatattc gtatattagt gatgaattat ctatactagg
     2521 ttataaagaa attaaaggaa cttttttaac accagaaatt tattctacta tgtcagaaga
     2581 agaacaaaat ttgttaaaac gagatattgc cagtttttta agacaaatgc acggtttaga
     2641 ttatacagat attagtgaat gtactattga taataaacaa aatgtattag aagagtatat
     2701 attgttgcgt gaaactattt ataatgattt aactgatata gaaaaagatt atatagaaag
     2761 ttttatggaa agactaaatg caacaacagt ttttgagggt aaaaagtgtt tatgccataa
     2821 tgattttagt tgtagtcatc tattgttaga tggcaataat agattaactg gaataattga
     2881 ttttggagat tctggaatta tagatgaata ttgtgatttt atatacttac ttgaagatag
     2941 tgaagaagaa ataggaacaa attttggaga agatatatta agaatgtatg gaaatataga
     3001 tattgagaaa gcaaaagaat atcaagatat agttgaagaa tattatccta ttgaaactat
     3061 tgtttatgga attaaaaata ttaaacagga atttatcgaa aatggtagaa aagaaattta
     3121 taaaaggact tataaagatt gattatataa tatatgaaaa gctattataa aagacattag
     3181 tattaaatag tttaaaaaaa tgaaaaataa taaaggaagt
//
LOCUS       DAXQKX010000123         3079 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.133, whole genome shotgun sequence.
ACCESSION   DAXQKX010000123 DAXQKX010000000
VERSION     DAXQKX010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3079)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3079)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3079
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.133"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..156
                     /locus_tag="ACF3MF_002778"
     CDS             <1..156
                     /locus_tag="ACF3MF_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001574277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HFE3928670.1"
                     /translation="LSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
     gene            720..1982
                     /gene="mobV"
                     /locus_tag="ACF3MF_002779"
     CDS             720..1982
                     /gene="mobV"
                     /locus_tag="ACF3MF_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobV family relaxase"
                     /protein_id="HFE3928671.1"
                     /translation="MSYAVCRMQKVKSAGLKGMQFHNQRERKSRTNDDIDHERTRENY
                     DLKNDKNIDYNERVKEIIESQKTGTRKTRKDAVLVNELLVTSDRDFFEQLDPGEQKRF
                     FEESYKLFSERYGKQNIAYATVHNDEQTPHMHLGVVPMRDGKLQGKNVFNRQELLWLQ
                     DKFPEHMKKQGFELKRGERGSDRKHIETAKFKKQTLEKEIDFLEKNLAVKKDEWTAYS
                     DKVKSDLEVPAKRHMKSVEVPTGEKSMFGLGKEIMKTEKKPTKNVVISERDYKNLVTA
                     ARDNDRLKQHVRNLMSTDMAREYKKLSKEHGQVKEKYSGLVERFNENVNDYNELLEEN
                     KSLKSKISDLKRDVSLIYESTKEFLKERTDGLKAFKNVFKGFVDKVKDKTAQFQEKHD
                     LEPKKNEFELTHNREVKKERSRDQGMSL"
     gene            2227..>3079
                     /locus_tag="ACF3MF_002780"
     CDS             2227..>3079
                     /locus_tag="ACF3MF_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HFE3928672.1"
                     /translation="MCPNSSIYSDEKSRVLVDKTKSGKVRPWREKKIANVDYFELLHI
                     LEFKKAERVKDCAEILEYKQNRETGERKLYRVWFCKSRLCPMCNWRRAMKHGIQSQKV
                     VAEVIKQKPTVRWLFLTLTVKNVYDGEELNKSLSDMAQRFRRMMQYKKINKNLVGFMR
                     ATEVTINNKDNSYNQHMHVLVCVEPTYFKNTENYVNQKQWIQFWKKAMKLDYDPNVKV
                     QMIRPKNKYKSDIQSAIDETAKYPVKDTDFMTDDEEKNLKRLSDLEEGLHRKRLISYG
                     GLLKEIHK"
BASE COUNT         1152 a          404 c          634 g          889 t
ORIGIN      
        1 ttatccatac ccttacttga tcaaaggttg ttacctatgg aagttgatca gtcaacttat
       61 ctgtatagta atttgttatt acttttttca ggaatcattg tcattagttg gctggttacc
      121 ttgaatgtat ataaacattc tcaaagggat ttctaaatcg ttaagggatc aactttggga
      181 gagagttcaa aattgatcct ttttttataa caggaattca aatctttttg ttccattaaa
      241 gggcgcgatt gctgaataaa agatacgaga gacctctctt gtatcttttt tattttgagt
      301 ggttttgtcc gttacactag aaaaccgaaa gacaataaaa attttattct tgctgagtct
      361 ggctttcggt aagctagaca aaacggacaa aataaaaatt ggcaagggtt taaaggtgga
      421 gattttttga gtgatcttct caaaaaatac tacctgtccc ttgctgattt ttaaacgagc
      481 acgagagcaa aacccccctt tgctgaggtg gcagagggca ggtttttttg tttctttttt
      541 ctcgtaaaaa aaagaaaggt cttaaaggtt ttatggtttt ggtcggcact gccgacagcc
      601 tcgcagagca cacactttat gaatataaag tatagtgtgt tatactttac ttggaagtgg
      661 ttgccggaaa gagcgaaaat gcctcacatt tgtgccacct aaaaaggagc gatttacata
      721 tgagttatgc agtttgtaga atgcaaaaag tgaaatcagc tggactaaaa ggcatgcaat
      781 ttcataatca aagagagcga aaaagtagaa cgaatgatga tattgaccat gagcgaacac
      841 gtgaaaatta tgatttgaaa aatgataaaa atattgatta caacgaacgt gtcaaagaaa
      901 ttattgaatc acaaaaaaca ggtacaagaa aaacgaggaa agatgctgtt cttgtaaatg
      961 agttgctagt aacatctgac cgagattttt ttgagcaact ggatccagga gaacaaaaac
     1021 gattttttga ggaaagttat aaattatttt ccgaacgata tggcaagcaa aatattgctt
     1081 atgcaacagt tcataatgat gagcaaaccc ctcacatgca tttaggtgtt gtgcctatgc
     1141 gtgatggaaa actgcaagga aaaaatgtgt ttaatcgtca agaactgtta tggctacaag
     1201 ataaattccc cgagcatatg aaaaaacagg gttttgagtt gaagcgtggt gaacgtggct
     1261 ctgaccgtaa acatattgag acagctaaat ttaaaaaaca aactttggaa aaagagattg
     1321 attttctaga aaaaaattta gcagttaaaa aagatgaatg gactgcttat agcgataaag
     1381 ttaaatcaga tttagaagta ccagcgaaac gacacatgaa aagtgttgaa gtgccaacgg
     1441 gtgaaaagtc catgtttggt ttgggaaaag aaataatgaa aacagaaaag aaaccaacca
     1501 aaaatgttgt tatatcggag cgtgattata aaaacttagt gactgctgcg agagataacg
     1561 ataggttaaa acagcatgtt agaaatctca tgagtactga tatggcgaga gaatataaaa
     1621 aattaagtaa agaacatggg caagttaaag aaaaatatag tggtcttgta gagcgattta
     1681 atgaaaatgt aaatgattat aatgagttgc ttgaagaaaa caagtcttta aagtctaaaa
     1741 taagcgattt aaagcgtgat gtgagtttaa tctatgaaag cactaaggaa ttccttaagg
     1801 aacgtacaga cggcttaaaa gcctttaaaa acgtttttaa ggggtttgta gacaaggtaa
     1861 aggataaaac agcacaattc caagaaaaac acgatttaga acctaaaaag aacgaatttg
     1921 aactaactca taaccgagag gtaaaaaaag aacgaagtcg agatcaggga atgagtttat
     1981 aaaataaaaa aagcacctga aaaggtgtct ttttttgatg gttttgaact tgttctttct
     2041 tatcttgata tatatagaaa taacgtcatt tttattttag ttgctgaaag gtgcgttgaa
     2101 gtgttggtat gtatgtgttt taaagtattg aaaaccctta aaattggttg cacagaaaaa
     2161 ccccatctgt taaagttata agtgaccaaa caaataacta aatagatggg ggtttctttt
     2221 aatattatgt gtcctaatag tagcatttat tcagatgaaa aatcaagggt tttagtggac
     2281 aagacaaaaa gtggaaaagt gagaccatgg agagaaaaga aaatcgctaa tgttgattac
     2341 tttgaacttc tgcatattct tgaatttaaa aaggctgaaa gagtaaaaga ttgtgctgaa
     2401 atattagagt ataaacaaaa tcgtgaaaca ggcgaaagaa agttgtatcg agtgtggttt
     2461 tgtaaatcca ggctttgtcc aatgtgcaac tggaggagag caatgaaaca tggcattcag
     2521 tcacaaaagg ttgttgctga agttattaaa caaaagccaa cagttcgttg gttgtttctc
     2581 acattaacag ttaaaaatgt ttatgatggc gaagaattaa ataagagttt gtcagatatg
     2641 gctcaaagat ttcgccgaat gatgcaatat aaaaaaatta ataaaaatct tgttggtttt
     2701 atgcgtgcaa cggaagtgac aataaataat aaagataatt cttataatca gcacatgcat
     2761 gtattggtat gtgtggaacc aacttatttt aagaatacag aaaactacgt gaatcaaaaa
     2821 caatggattc aattttggaa aaaggcaatg aaattagact atgatccaaa tgtaaaagtt
     2881 caaatgattc gaccgaaaaa taaatataaa tcggatatac aatcggcaat tgacgaaact
     2941 gcaaaatatc ctgtaaagga tacggatttt atgaccgatg atgaagaaaa gaatttgaaa
     3001 cgtttgtctg atttggagga aggtttacac cgtaaaaggt taatctccta tggtggtttg
     3061 ttaaaagaaa tacataaaa
//
LOCUS       DAXQKX010000124         3040 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.134, whole genome shotgun sequence.
ACCESSION   DAXQKX010000124 DAXQKX010000000
VERSION     DAXQKX010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3040
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.134"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..856
                     /locus_tag="ACF3MF_002781"
     CDS             <1..856
                     /locus_tag="ACF3MF_002781"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928673.1"
                     /translation="FVAESLYDPFTKDIQVLGMPDFIDYNEYEVIVNSEVKNEEADGM
                     ENVNQTAIDSASTVFEKVGEDYIGSKSRFGDILIGAPYSEAFVKAYANERKDVLVIPQ
                     TIEYSAFLHNEEMKKVAKSGQEAIKDRAQARRDEIVEQAKADVERLKENNIRLRTFNI
                     SLEANRKDRSVEAIAKRPKSNRAFYGIAKAAPDDCFNIHIGKAIAIRRALGLAVPDEY
                     LNAPQPTEVRVGDVIMPSVLKKNTPRKVVATDVEVDAIANVCCLDSIMATNNATIIDD
                     SREEVIGE"
     gene            853..1056
                     /locus_tag="ACF3MF_002782"
     CDS             853..1056
                     /locus_tag="ACF3MF_002782"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928674.1"
                     /translation="MSTGQLTFGTPEYVRVTKLAERKGRTDELIDKIEALTEELHTSD
                     YYIGSYEQRRRVELITLTLAELI"
     gene            1076..1858
                     /locus_tag="ACF3MF_002783"
     CDS             1076..1858
                     /locus_tag="ACF3MF_002783"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928675.1"
                     /translation="MTNENTCVLADGCKAAGTDACTRHCTHFIAMHGASGEGGRSGAA
                     GLPREYRLVTLKNSPARADQSEAYKAAEAYASTFNRQFDQQSGSVAAADRIKSLYLVS
                     ESPGTGKTTTAAALLNEWLRVHYSGSLRRGLEPLQRPAYFLDVNAWQNDYNEFNRPRV
                     PDSVAEPAAARYYRALEAAKTAPFAVLDDIGVRDATDGFRGDLHTVINARVTNQLPTI
                     YTSNIALDQIWQVFGERRLADRVGDLCREIEFVGESKRGMRR"
     gene            1855..2166
                     /locus_tag="ACF3MF_002784"
     CDS             1855..2166
                     /locus_tag="ACF3MF_002784"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928676.1"
                     /translation="MNIPLSIVEAGKTDEYVRLQKRHDYFKEKQNEVLEAAREASRTL
                     YSASIHRQSFYGNIIPNGFVIEIANAAKKCMSANRRVEHVEAILSVVENDIKRLEEGG
                     A"
     gene            2167..2676
                     /locus_tag="ACF3MF_002785"
     CDS             2167..2676
                     /locus_tag="ACF3MF_002785"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928677.1"
                     /translation="MKTEFTFGDIVSVSGYENRIFYVDAWREVKETDEWGVSEYVEFE
                     LTDAINGEFLDAFETDLRLVCRKQFAEDYLLTYDVTNYPEPSGPSFHFTDDFSFGIGY
                     AKKEAVGMANGPKETPKREQEAGAKRKTDELLDEYNDNMRLYETFGDAEYKTKADAVI
                     AKLRREVSE"
     gene            2673..2927
                     /locus_tag="ACF3MF_002786"
     CDS             2673..2927
                     /locus_tag="ACF3MF_002786"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928678.1"
                     /translation="MNAKEASEKASDVRAIINRETRTAIYKTINRLSGMGRYQCYKNT
                     SHLYKDEVKTLIKELRALGYKVRRDSFNTIYIRWEREASE"
BASE COUNT          897 a          629 c          869 g          645 t
ORIGIN      
        1 tttcgtagcg gaatcactat atgatccgtt cactaaagac atacaagttt taggaatgcc
       61 ggattttatc gactataacg aatacgaggt tatcgtcaat agcgaagtta aaaacgagga
      121 ggctgacgga atggaaaacg taaatcaaac ggctattgat agtgcgagca cagtattcga
      181 aaaggtaggc gaggattata tcggaagcaa gtcgaggttc ggcgatattc taatcggggc
      241 accatattcg gaagcattcg taaaagccta cgcaaacgaa cgaaaagatg tcctcgtgat
      301 tccgcagaca attgaatatt ctgcgtttct ccacaacgag gaaatgaaga aagtcgctaa
      361 gagcggacag gaggcgatta aagatcgagc acaagcccgc cgtgatgaaa tcgttgagca
      421 ggcgaaggcg gacgttgagc gacttaagga gaataacata cggctgagga cgtttaacat
      481 ttcgttagag gctaatcgaa aagacagatc cgttgaagct atcgcaaaga gaccaaagag
      541 taatagggcg ttttatggaa tcgcaaaagc cgcacctgac gactgcttca acattcacat
      601 cggaaaggcg attgcgataa gacgtgcgct gggcttggcg gtgcctgacg aatacttgaa
      661 cgctccgcag ccgactgagg ttcgtgtagg cgacgtaatt atgccgagcg tcctgaagaa
      721 aaatacacca cgaaaagtag tcgctacaga tgtggaggta gacgcaatag ctaacgtgtg
      781 ttgtctagat tcgataatgg cgacaaataa cgcaacaatc atcgacgact cacgcgaaga
      841 ggtgatcggt gaatgagtac cggtcagtta acgtttggaa cgcctgaata cgtaagagta
      901 acgaaattgg ccgaaaggaa aggccgtacg gatgagttga tcgacaagat cgaagctttg
      961 acggaagaac tccataccag cgattattac attggttcat atgaacagcg gagaagagtc
     1021 gaattaatta cacttacgct ggcggagttg atctaacgaa aggaggtccg cgaatatgac
     1081 taacgaaaat acttgcgtac tcgctgacgg atgcaaagcg gccgggactg acgcatgtac
     1141 gaggcactgt acgcatttca tcgcgatgca cggcgcttca ggcgaaggtg ggcgatcagg
     1201 ggcggcaggg cttccgaggg agtatcggct cgtcacgctg aagaattcgc cggctcgcgc
     1261 tgaccaatcc gaagcttata aggcggccga ggcttatgcg tctacattta atcgtcaatt
     1321 cgatcagcaa tccggttcgg tagcggcagc ggatcgcatc aagtcgctat acctcgtaag
     1381 cgaatcgccc ggcaccggta agacgacgac ggccgccgca cttcttaacg aatggctgcg
     1441 cgtccattat agcggctccc tgcggcgagg cctcgaaccg ttacagcggc cagcgtattt
     1501 cctcgatgtg aacgcgtggc agaacgacta taacgaattc aaccggcctc gtgttccgga
     1561 ttcagtcgca gagccggcgg ccgcccggta ttatcgcgcg ttagaagcgg ctaagacggc
     1621 gccatttgcg gtgctggacg atataggggt gcgtgatgca acggacggct tccgtggtga
     1681 tttgcatacc gttattaacg caagagtaac gaatcaacta ccgacgatct acacgagcaa
     1741 cattgcgctc gatcaaattt ggcaagtatt cggtgagcga cgtctggccg atcgggtggg
     1801 cgacctatgc cgcgagattg aattcgtagg cgaatcgaaa agggggatgc gtagatgaat
     1861 attccgttaa gtatcgttga agcgggaaaa accgacgagt atgtgcggct gcaaaaaagg
     1921 cacgattatt ttaaagagaa gcaaaacgaa gtcttagaag cggctagaga ggcgtcacga
     1981 acgctttact cagcctctat ccaccgccaa agtttctatg gaaacattat accgaatggt
     2041 tttgtaatcg aaatagcgaa cgcggcgaaa aagtgtatgt cggcaaatag aagagtagag
     2101 catgtggaag ctatcctttc cgttgttgaa aacgatataa aaagattaga ggaaggcggt
     2161 gcgtagatga aaacggaatt caccttcgga gatatcgtct cggtttccgg gtacgaaaat
     2221 cggatattct acgtcgatgc ttggcgcgaa gtaaaggaaa ccgatgagtg gggcgtaagt
     2281 gaatacgtcg agttcgagct gaccgacgcc ataaacggtg aattcctcga cgcgttcgaa
     2341 acggatctgc ggctggtctg tcggaaacag ttcgcggaag attacctctt aacttacgac
     2401 gtgacgaatt atccggagcc gtcgggccca tcgttccact ttacggatga tttttctttc
     2461 ggaataggtt acgcgaaaaa ggaggcggtt gggatggcga acgggccgaa ggaaacgccg
     2521 aagagggaac aggaggccgg ggcgaaacgg aagactgacg agctactgga cgaatacaac
     2581 gataacatgc gcctatatga gacgtttggg gatgcggaat ataaaacgaa ggctgacgct
     2641 gtgatagcga aattgagacg ggaggtgagc gaatgaatgc gaaggaagct tccgagaaag
     2701 cgtctgatgt gcgggctata atcaaccgag aaactcggac agcgatttat aaaacaataa
     2761 atcgtttatc cggaatgggg cggtaccaat gttataaaaa cacctcgcat ctttataaag
     2821 atgaagtaaa gaccctcata aaagaattgc gggctttagg ctataaagta cgccgagact
     2881 cttttaacac aatttatatt cgatgggaaa gggaggcgag cgagtaatgg gcgtatggag
     2941 atcggattgg gttttgattg gcgcggatat aggatacgat caattcgatg aatacaagta
     3001 cgaagaatac gaaaaatttg agggcgtgga tagaccgggt
//
LOCUS       DAXQKX010000125         2732 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.135, whole genome shotgun sequence.
ACCESSION   DAXQKX010000125 DAXQKX010000000
VERSION     DAXQKX010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2732
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.135"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(443..1417)
                     /gene="bsh"
                     /locus_tag="ACF3MF_002787"
     CDS             complement(443..1417)
                     /gene="bsh"
                     /locus_tag="ACF3MF_002787"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HFE3928679.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTITPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
     gene            1580..1837
                     /locus_tag="ACF3MF_002788"
     CDS             1580..1837
                     /locus_tag="ACF3MF_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928680.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(2069..2500)
                     /locus_tag="ACF3MF_002789"
     CDS             complement(2069..2500)
                     /locus_tag="ACF3MF_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HFE3928681.1"
                     /translation="MIGEKMMDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVL
                     SASIPILIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEK
                     LLYITKTSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          998 a          405 c          346 g          983 t
ORIGIN      
        1 tatagtatca gtcctataaa ataaacatct aattaattac tctaaatcct aattataagc
       61 cttttttctc actttttttc aaaaatatgg tatgcttctt agtgaattca aatataaaag
      121 agtttaaagc gtaatacact tatggggaag tggtttgggg tgcgctttaa actcttcttt
      181 attattatct cacagcatgc ttaaaaggtc tatggattaa gttatgtaaa aaagtgcctc
      241 tttaaacgtc ctaaaatcca aacaaggata gcataatata cactatcgtt gatccagaaa
      301 acaggtaaat aaattttgca aaagcaataa gttaaaaaca ttacaaaaaa gacaaggata
      361 tcacatcaag aaaaaatgtt ttgaaaatat ctttgccttt ttgtattata tctatattaa
      421 ataatcaatc acaacacatt aactaattta tatatttaat ttgttgtttt tctataattg
      481 gataactaat taacttatga ctatctaagt cttctttatt catatcaatt gcagtaattt
      541 gactgtcttc atatgttcga taataataga ttcctttgtc aacattgcaa caagaagaat
      601 aaattgtata ttcatatttt ccatcaccaa catcacacaa acctttttgt tgttctactg
      661 aacctaagat atggaaaaat tgactaatac tttctgactc tgaatctcca gatacagaat
      721 tcagcttcgt aaaagtcgct ttaacaaaac gagatactga ggataaatct ccaggcaagc
      781 ctatccctcc cataccgcgg ctataggcat tcaaacttat ttgatttgaa aaattatttt
      841 taggagtttc actcgataag acacgataat tgtttaaatt aaataattga tagtcaaatg
      901 aaggattatt ggtaagaacg cccacagggt tatcatatat atgaagtcca tctttcatac
      961 tttcaatgac aattgatttt tctttatcag ctaatagcca atgtaaaggg gataaaggaa
     1021 gttcgtcact ataatttata tttgctaaat tgatattttt taacaatttt ttagcttctc
     1081 ctactgttga gcattgtcct aaaatccaag gaataaattc aaaaggagat acattgtctt
     1141 tcccttcttg tatttcttta taatcagcat acccagaaaa atttagtcca gccatactca
     1201 atcctttttc atttgtcgca tcgtaataaa gagggtagtc agctatacca gcggcaatac
     1261 caatcattgc ataatgagta tccaaatcat ttacctttcg aaaattcaac ttataatttc
     1321 ttggagtaat agtgactact tcattgtaag atatttcata atcaaaattc cttccaaaat
     1381 aatgatcact tgttacataa gtaatagacg tacacatagt ttattcctcc taaatatttt
     1441 tctgtccacg ttcatattac tccaaagttt tcctcattcc aaaagaaaag cacagaatac
     1501 acaaagaagc gtttttattt gtataaacta tatcaaagtt ctatacttaa attatcaaat
     1561 aaaaaggacg tgaagataaa tgtcaaattt agaaaacaaa gaagaaaaag ttgtaaacaa
     1621 aattgtttct gttgtcaata aactggataa agagttagac gaacttgata cgttatctga
     1681 aaatccagaa aaaaaacata acctaaaaaa atggttagtt gaacgaaagg ctattcatga
     1741 aattaaaaaa gttcttcatg aagctgataa atatgaaaaa tatgatgaaa aagaacttga
     1801 taaagaattt aaagaaatca atgacttgtt actataattg atttatacga ctcatttttg
     1861 agtcgtcaga ctgcaaacaa cactctaaat ttaggagttt gtctacagtc tgaataaatt
     1921 ttaaatttat tgtccataat gttattatga atttatagca ttaagaaaag agataagact
     1981 ttacattttt ttaggaatgt aaagtcttat ctcttttctt aattgtacaa ttagtattat
     2041 ctgcactact ttctaattaa ataaattttt agttattaac ttgattaaaa tcagagataa
     2101 tatcatttaa ttcagtttga agggttgtaa cgattaaatg gaaattttct tcatctgttt
     2161 tattatatgg ggatgttttc gttatatata acaacttttc tttttcaatt ttcattaata
     2221 actctgtcga agtctgtact ttatcttgat aattaaatgc agacatccca ctttgtataa
     2281 ttgtaattat tgctgaagca attgaaacaa tcaatagtaa agacctgtgt tcggaagcct
     2341 gatcaattaa tattgggata ctagctgata agactatttt tataatattt ccgataccaa
     2401 ttactctatt ataaaatcga atttcttttt ttaatctatc gattgtagaa tcaatagatt
     2461 cgataaacgc tttttgatcc atcattttct ctccaatcat tttattaaaa tcattaacaa
     2521 aaatattata ataggattta agtaagttct aactaatcac atataaaaat aaaaaaacat
     2581 ttgtatttta tcaaagtttt attatacttg tcaatttgtg tacatcctaa aatataagct
     2641 atttgtttac ttctgtagaa tatatacttt gttgttagat aagttgcaca tgtttataga
     2701 atctaaataa taaattttta tgtaccgccc ct
//
LOCUS       DAXQKX010000126         2715 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.136, whole genome shotgun sequence.
ACCESSION   DAXQKX010000126 DAXQKX010000000
VERSION     DAXQKX010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2715)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2715)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2715
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.136"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..172
                     /locus_tag="ACF3MF_002790"
     CDS             <1..172
                     /locus_tag="ACF3MF_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HFE3928682.1"
                     /translation="RPIKRRNKFYQSLRTASSTIKGMETIRGIYKKNRRNGMLFGFSV
                     STEIKVLMGITA"
     gene            312..851
                     /locus_tag="ACF3MF_002791"
     CDS             312..851
                     /locus_tag="ACF3MF_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928683.1"
                     /translation="MWSLVGIVLIIFTVTAATEANYSHKIQSYKGRLVMTKKDVTRYT
                     SSRTGGLYDYAPLDALKYKDHLKKHEVKVGDRWENASHKAYNSKIVYTVEDADEQNIT
                     LPVFNYWGTVMKVNGKKSTIENDNGLVSIKGTGKRTIVEVSSTYPTTMILSLLISSIT
                     FIFLFTRYLIRCCGEMKID"
     gene            1859..>2715
                     /locus_tag="ACF3MF_002792"
     CDS             1859..>2715
                     /locus_tag="ACF3MF_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISLgar5 family transposase"
                     /protein_id="HFE3928684.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHHYTPQTMSNITKSFTEEVTAFKGRELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIVVGIRPDGSKEVLSYAIAPTESITIWEEILLDLQERG
                     LKNVLLFITDGLKGMVGAISRFYPKARFQHCCVHVFRNISHKVRVNNRKEVCDDFKMV
                     YQASSKEVA"
BASE COUNT          955 a          422 c          497 g          841 t
ORIGIN      
        1 tcgacctatt aaacgacgaa ataaatttta tcaaagtctc cgtacagcct cttccacgat
       61 taagggcatg gaaaccattc gaggaatata taaaaagaac cgaagaaatg gaatgctctt
      121 cggcttttcg gtgtctactg aaatcaaggt attaatggga ataacagcct aagatatttg
      181 gagttcagag agggcgcgtt tgattttcaa acttcgcaac agaaccgaga accttgggtt
      241 ttcaagtgct ttttggttca ttaatcttaa ccatagtgtt tttaaagtgg aaaacaagca
      301 acaaaaaaag tatgtggagc cttgtaggaa tagttcttat tatttttact gtgactgcag
      361 caacagaagc aaattattcg cataaaattc agtcgtataa aggtcgttta gttatgacca
      421 aaaaagatgt tacacgttat acatcctcaa gaactggagg cctatatgac tatgcaccat
      481 tagatgcatt gaaatataaa gatcatttaa agaaacatga agtaaaagtt ggtgatcggt
      541 gggagaatgc atctcataaa gcatataatt ccaaaatagt ctatacagta gaagatgccg
      601 atgagcaaaa tatcacatta cctgtattca attattgggg aacagttatg aaagtaaatg
      661 ggaaaaagag cactatagaa aatgacaatg gtttagtgtc tattaaaggt acggggaaaa
      721 gaactatagt tgaggtttca tctacgtatc caactacgat gattctatct ttattaatta
      781 gttcaataac ttttatattc ttatttacac gttatttaat aagatgctgc ggtgaaatga
      841 aaatagatta gatagatatt ataaatatgt tgattctatt ttcatagcaa tggagaaaat
      901 acattagcaa tatataaaag aaggtatcaa gagtcacagt gaatttattc cgaaaagtga
      961 aaagagcaaa tataaaattt aataaaaata tagaactaaa taggaaaacg tagacgtaat
     1021 tttctacgtt ttccttttca tatatattaa atattacgga aaattataca aactaattta
     1081 gtgttttgtt tgtaattcct aattttgctc cacttttaga taatttttag gtctatttaa
     1141 ctcatcagac attctatgct catttttctc caaatttgtt tcaactcttt cgtacttaat
     1201 tttgcgtatt tgaaaattct tcttttagag tacttttatt acgatactag tatgatatat
     1261 atctatagca aacagttaaa atcttcctaa aataagcgaa tagcattcct aaaacctata
     1321 aaatttttag atgaagcgac aagtggacaa ttaataaact acttgaacat gaaattatgg
     1381 atcacctttc aaatttagaa aatggaattc ttatacttat tgcgcaacat ttattgattg
     1441 caaaattatg tgacaaaaag aactagtaga agaaggaata atggcttgat aataaagtac
     1501 tacctattaa aggtagtact ttatttaatt tagtataaat taacatacta ctatatttta
     1561 ggtttcatat tatataaatt aataatatac taccatttgt tggtagtata atttaaaggt
     1621 aataagttat tcttttatta ctatgtttgg gttttatagc aaagaaagtt taataagagt
     1681 ttggacctag caaacaatat taatgaggtc attaaatctt attatcttta gtaatataac
     1741 gaaatatcta cacagacaaa attagagagt gtaaaatatt ttgtgtaaat agaaaaaagg
     1801 aaatcccttc tgtagaatag agttaccaca aaacattcac agaagagagg acttccctat
     1861 gaacgatttt actacagaaa ttctaaagac tctagcgaac aaaggcgatt tgaatgaatt
     1921 attccgtgtc catttggaaa aagcagtcaa tacgcttctc aaaacggagt taacggcttt
     1981 cctagattac gaaaagtatg atcgcattgg ttttaacacg ggtaattctc gtaacggctc
     2041 ctatgaccgt acggtcaaga ccgagtatgg ggaacttcat ctccagattc cgcgcgaccg
     2101 caatggcgag ttcaagcaac agactgttcc tgcttataga cggacgaatg acacgttaga
     2161 ggagaccgtc attcacctct tccgaaaagg tattaccatg tcggaaatcg cagacttgat
     2221 tgagaaaatg tatgggcatc actacacgcc acaaaccatg tccaatataa caaaatcatt
     2281 tacagaagag gtaacggcgt ttaaagggcg agagcttcat gaccgttatg ctgctattta
     2341 tatggacgca acgtatattc cgttaaagcg gaaaaccgtc gccaaggaag ctattcatat
     2401 cgtagttggc attcgcccgg acggatcaaa ggaagtattg agctatgcga ttgcaccgac
     2461 tgaatccatc acgatttggg aggaaatttt attagacctt caagagcgcg gtttgaaaaa
     2521 tgtcctcctg ttcatcacgg atggcttaaa ggggatggta ggagcgatta gtcggttcta
     2581 tcccaaagct cgttttcaac attgttgtgt acacgttttc cgtaatatca gtcacaaagt
     2641 gcgtgtcaat aatcgtaagg aagtctgtga tgattttaaa atggtgtatc aagcctcatc
     2701 taaagaggtg gcgtt
//
LOCUS       DAXQKX010000127         2699 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.137, whole genome shotgun sequence.
ACCESSION   DAXQKX010000127 DAXQKX010000000
VERSION     DAXQKX010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2699
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.137"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            700..2610
                     /gene="ltrA"
                     /locus_tag="ACF3MF_002793"
     CDS             700..2610
                     /gene="ltrA"
                     /locus_tag="ACF3MF_002793"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFE3928685.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
BASE COUNT         1057 a          419 c          554 g          669 t
ORIGIN      
        1 aaaagctaag gcactaataa aagaacgaaa aagtttggtt attaggagaa ctgataatct
       61 gacaggtgga atgatgaagt aacgctctga aacgcctgcc ctgagcctcc gacaagcatt
      121 gtatgaggaa actcagaatg tttgaagctc ggtaaagacg gctgaaagat accgtaatag
      181 ttgatgaaca tatatcttct atcgaaaact atccagaggt gggtagcgta tccaacaggt
      241 cgggggtcta taaaatatct atggttagaa tgttctataa ggaactgacg aaacagcgaa
      301 tgtacgggtc taaatttgaa ctttgtagaa atgcaaaggt acgagaaatc gtagctggtg
      361 tggcaaagta agaatatagg ttatgaaatg ccatataacg ttacaggcgg tatcaagcca
      421 gcaggcttat agctagtgac ctaaggatat atatgtatag ataagattat cggaacgagg
      481 aaaggtattg ggttctcatc aagagaataa actgacgaag aacaataagc agttgaacta
      541 atgctgaaaa gcagagggcg aacctaagaa attcttgtaa tgagaatgga ggaatgccct
      601 caagtcgtgt atatattaga aaagtattat gttgtttcaa taaggattac gagtaagata
      661 aaaaagctca ctcaatttca agtaaaggag tgaagcctta tgcctaaaaa taaaaatgaa
      721 acattgtgtg tagaagattt aagacacgct gaatattacg aaatgcaaaa cacctttgat
      781 gatttatatg ccaaaagtaa gaatggagat attttcactc atcttatgga tattatccta
      841 tcgagagaaa atatattact ggcatatcga aatatcaaag caaatgcagg cagtaaaaca
      901 gcaggaacag acggtacaat aattaaagat attggcaaat tgccagcaga aacagttgtc
      961 aaaaaagtaa gatacattgt tgcaggcagt ccacatgggt atcgacctaa gccagtgagg
     1021 cgaaaagaaa taccaaaacc aaatggtaaa accagacctc taggtattcc ttgtatgtgg
     1081 gacaggctta tacaacaatg tataaaacaa gtattagaac caatctgcga agctaaattt
     1141 agtgaaaaca gctatggttt tagacctaat aggtcagttg aaaatgcaat aaaagcaacc
     1201 tataaccgcc tacaaatcag ccagctacat tatgtgattg aatttgatat taagggtttc
     1261 tttgacaacg tgaaccattc caagctgata aaacagatat gggctatggg aatacgggac
     1321 aagcacttga tattcatttt aaaaaggata ttaaaagctc caatcaaaat gactaacggt
     1381 acaataacat atccagagaa aggaactccg caagggggaa taatatcccc actactagca
     1441 aacattgttc ttaatgagtt agaccattgg gtagaaagcc aatggcagga aaatcctgtt
     1501 acaaaaaact atgtggttca tatcaataaa agcggtagcc catgtaaaag caacgcttac
     1561 aaagaaatga agaaaacaaa gttaaaggaa atgtatatgg ttcgttatgc agatgatttt
     1621 agagttttct gccgctacaa ggaaagtgct gaaaaagcca aaatagcaat cactcaatgg
     1681 attgaacaac gattaaaatt ggaagtatca caagaaaaaa caagaattgt aaatgttaga
     1741 aaaagatact ccgactttct tggtttcaag attaaaatga taccgagaag aaagaagtta
     1801 gttgttaaat cacatataag tgataaacaa ttcaaaaacc aaaaagacaa gctggtatca
     1861 caggcaaaga aaattgcttc tccctcaaaa gggaaaacgg aattagaaga aacaagactt
     1921 tataattcaa tggtattagg tatgcaaaat tattatcaga ttgcaacgaa tgtaaatctg
     1981 gattgtatga aactgaatag agctgtaatg gctatcttca ctaacagatt aggtacaaac
     2041 aaaaggggca gattgagaaa aacaggcaga caacttacga caaaggaggc aacaagatat
     2101 ggtaaatcta aaatgcttcg gtatgttgct ggcgagggcg aacctatttt ccctgttgga
     2161 tatatccaac acagaaaacc aatggcaaag gtgtatttag cgaattgcta cactctagag
     2221 ggaagaaaat ttatccacac caatctaagt gttgataaat tactgatgta ccagttaatg
     2281 aaattatctt tggaaaatcg cacaatagaa tacgcagaca atcgaatttc gctattttct
     2341 gctcaacatg gaaaatgtgc tataactctg gaagaatttc aacaagctaa tgaaatacat
     2401 tgtcatcata ttgtaccaac tggagctggt ggaaatgacg attataaaaa tcttattttg
     2461 gtaaaagagg cggtacaccg tctaatacac gctaaaacag aagaaacaat acaaaaatat
     2521 atagctctat tgaagctaaa taaagtccag ctcataagac taaataaata tagagtatta
     2581 gctggcaatc aagaattaaa cttgatatag gtctactaca taaatacttt tcaatataaa
     2641 cacgatggaa cgcggagtgc ggtgaaagtc gcacgctccg tgtgaatggg gggaaaagt
//
LOCUS       DAXQKX010000128         2634 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.138, whole genome shotgun sequence.
ACCESSION   DAXQKX010000128 DAXQKX010000000
VERSION     DAXQKX010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2634
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.138"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            5..1150
                     /locus_tag="ACF3MF_002794"
     CDS             5..1150
                     /locus_tag="ACF3MF_002794"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HFE3928686.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            1321..1779
                     /locus_tag="ACF3MF_002795"
     CDS             1321..1779
                     /locus_tag="ACF3MF_002795"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0043768 - S-ribosylhomocysteine lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HFE3928687.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            1938..2408
                     /locus_tag="ACF3MF_002796"
     CDS             1938..2408
                     /locus_tag="ACF3MF_002796"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HFE3928688.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(2461..2576)
                     /gene="rrf"
                     /locus_tag="ACF3MF_002797"
     rRNA            complement(2461..2576)
                     /gene="rrf"
                     /locus_tag="ACF3MF_002797"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          862 a          505 c          496 g          771 t
ORIGIN      
        1 aaacatgcac attcaaacaa aattgatcca cggaggcatc agtgaagatc ccacaacagg
       61 agctgtcagt gtacctattt atcaaacatc cacttatcgg caagatggcg tcggccagcc
      121 taaacaatat gaatattcaa gatctggtaa tcctactcgt tttgcattgg aagaactgat
      181 tgctgatttg gaaggcggtg ttcgaggatt cgctttttct tctggtcttt ctgggattca
      241 tgccgttttt tctctttttc aagctggcga tcatatctta ttaggagatg atgtctatgg
      301 aggaacattc cgtctatttg acaaagttct tactaaaaat ggtctcgagt acacgatcat
      361 agatacgagt aatcttgata aaatagaaca atccatcaaa cccaatacaa aagcacttta
      421 tcttgaaaca cctagcaatc cgcttctaaa gattactgat ttagaaaaaa gtgccactct
      481 ggctcatcaa catggattga tagttattgc tgacaataca tttgctactc cttattttca
      541 aagaccttta gatctcggtt ctgatatcgt tgtccatagc ggtaccaaat atctaggcgg
      601 acacagcgat gtagtagctg gtttagtgac ttctaaccat aaagatctag ccgatcagat
      661 cggattttac caaaatgcta tcggagccgt acttggtccc caagatagct ggttacttca
      721 gcgcggaatc aagacactaa gtgttcgtat ggaggaacat caaaaaaatg cttttgtggt
      781 agctgatttt ctattttctc atccagcagt agaaaaggtc tactatccag gattacccga
      841 tcatgaactc catggagttg ctaagcagca gatgagcggc tttagcggaa tgatttcttt
      901 tactttaaaa aatgaagaat ctgctattcc atttgttgaa tcactccaac tatttacttt
      961 agcagaaagt ttaggtggcg tagaaagttt agtggaaatt ccttctgtca tgactcatgc
     1021 gtctattcca aaagaaaaac gagaagaggc tggcataaag gacggcttga tccgtctttc
     1081 tgtaggaatt gagtatggtc aggatctcat aaacgattta gctcaggcat ttgacagaat
     1141 caagaactag aagtcccaat aaacgactta gcagaaaaat ctaaaaaata tttcagattg
     1201 ctacaccttg gaaacgataa gtgttagaat caagtagaaa gacgtttttg taaatttcac
     1261 taaataattc tttagtgaaa agcatcaaaa cgaatgaaca aacagatagg agtcttacaa
     1321 atgagaatga atgtcgaaag ttttaatctt gaccatacaa aagtcaaagc accttatgta
     1381 cgtgtagctg atcgaaaaac gggtgcgcat ggcgatgtca tcattaaata cgacgtccgc
     1441 tttaaacaac caaataaaga acacatggac atgccaagtc tacattcact tgagcacttg
     1501 actgccgaac taatccgcaa tcacgcagat tacatcgtag actggtctcc aatgggatgc
     1561 caaacaggct tttacttgac tgtattgaat catgaaagct acgaagacat tttagatgtt
     1621 cttgaagcaa caatgaaaga tgttcttgaa gctactgaag tacctgcaag caatgaaaca
     1681 caatgtggct gggctgccag ccatacacta gaaggtgcac aagctttggc tcgtgaattt
     1741 ttagcaaaac gcgatgaatg gtctgaagta gaagcatagt ttctaaaaga acgtaaagat
     1801 gagaagcaat atagctatct tatcttcgta ttttattaaa tatttattgt ctgaaaagag
     1861 ttctaaacgg gaaaacaaat agctagtttt cagtttagcg ctctttttat tatataaaat
     1921 agaaaggaga aaactttatg tctatttata attttgaaac tactttagaa gacggcactg
     1981 tctattcatt gaaaaaatat gcaggcaaac cgataatcat tgttaacact gcaacaaaat
     2041 gcggtctagc acctcaattt aaacaattag aagaacttta ccaagcttat cagacacaag
     2101 gtctggttat cttaggcttt ccttccaatc aatttaaaca agagctagat tcagcgactg
     2161 aagcagcaga agcttgtaaa accacttatg gcgttacctt ccctatgcat caattgattg
     2221 acgtaaatgg agaaaataca gatcctcttt ttacttatct taaaaatgaa gctcctggta
     2281 ctgtcactaa agcaataaaa tggaatttta ctaaattttt gattgataga aatggcaaag
     2341 taatcgaacg atttgcacca caaacttctc cattgaaaat gaccgctgca attgaatccg
     2401 ttctttaact taataaaaat aaaaaaagat gaactatttc tagttcatct ttttgccttt
     2461 gcgtggcgac gtcctactct cacaaggggc accccctcac tacaatcggc gctaagaagc
     2521 ttaacttctg tgttcggcat ggttacaggt gtatccttct cgctatcgcc accacactgt
     2581 ggtgttatct tttattgagt aaattttgtt cactcaaaac tggatttgaa gtca
//
LOCUS       DAXQKX010000129         2564 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.139, whole genome shotgun sequence.
ACCESSION   DAXQKX010000129 DAXQKX010000000
VERSION     DAXQKX010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2564
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.139"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            345..1271
                     /locus_tag="ACF3MF_002798"
     CDS             345..1271
                     /locus_tag="ACF3MF_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928689.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYMFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILITRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGNG"
     gene            1377..1640
                     /locus_tag="ACF3MF_002799"
     CDS             1377..1640
                     /locus_tag="ACF3MF_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFE3928690.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            1640..1912
                     /locus_tag="ACF3MF_002800"
     CDS             1640..1912
                     /locus_tag="ACF3MF_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFE3928691.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            1989..2318
                     /locus_tag="ACF3MF_002801"
     CDS             1989..2318
                     /locus_tag="ACF3MF_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFE3928692.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            2308..>2564
                     /locus_tag="ACF3MF_002802"
     CDS             2308..>2564
                     /locus_tag="ACF3MF_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFE3928693.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKVIPVLLCGTHE"
BASE COUNT          968 a          307 c          478 g          811 t
ORIGIN      
        1 acactgctat tagtgaaaaa ataagatatc aagtacgctc tattcccaaa aatttcgtga
       61 ctttactcat gagaggttca agtagtatat ttttaatcaa aattgacgta acttttaata
      121 aatactacct aaataaggta gtatttattt ttgtgtttta aaagagggag tccaatatat
      181 ctatgggaaa cttcttaaat attatgttgg tacatgaaaa tatacatccc tgctagacta
      241 tttacaacat tttactttgt acgtattctt gttttaaaag gaatgggata aaatataggt
      301 acaataacta tttgatgcta aatataatta atggaggaga gatagtgaac atacttaatg
      361 aaaaaagata tgtatggttt gctggtaaaa aatatattac tactttcaaa agattatccg
      421 agttaatgca gcagactgtt aaaagtgcta tgcctgaagg atacaagttt aattttgttc
      481 aatcttcagt atctactgaa agtatctatt tttcaattct ttctgagagt aggctttttc
      541 attttagaat aagttctcat gtaaagaaaa ctgatgttga tatatatatg ttccgtacaa
      601 ataattataa aaatttaaat gatttgagta gaagtatcag tgaatatctc aaggggaata
      661 gctatctcaa gattcgattt tcacatatat taattttact accatatttg aatgagaatt
      721 tcaccctaat tcaagtagat aagtctttca ttgcctcagg taatcaagga aatatgaata
      781 ttacaagtaa caaaacgtca cgtgtgctat tggcgttgat gggttacgga attctttata
      841 gagatgacca aaatggccag attctaataa ctcgggccgg gcgttcatta ttaatgaaat
      901 atagaaaatt tataccggaa gattttcaaa acttacagtt agaaaacatg cgtttagaag
      961 atttatttag attagcagaa gatgataagt atagatttga agttttgaaa attcaaaaga
     1021 atgaactatt gaataagtta tatcctgaga atgcgataaa agcacatttt ggtgatgcta
     1081 atcatatgta tagttggttc attcctaaaa gatttagagg gaaaatcaat gctggagatc
     1141 aagtgaaagt actcaatcga aatagtacag atgtcgtaat gataacagat atctatgtag
     1201 aagatgaaga tataatcaaa tatatgaagc ctgtgataaa acttgttaat aaaaataaag
     1261 gaaacggata acactttaca atgctgtttt ggtactccaa tttaaacaaa acaatcgaat
     1321 ttacgtactt aattaagtac gttagaatgg agatataaat tagaggggga gtagatatgg
     1381 caaaaactgt cttaaatcct agctcagcac ggaaaaattt ttataagttg ttgaaagatg
     1441 taaatgagaa tcatacggaa attgaaatca ttagtgagcg cagtgaaaat aatgcggtgc
     1501 ttattggttt ggatgattgg aaagcaatca aagaaacgct attacttgag caaataggca
     1561 ctttgggtgt tgttcgtaag cgagaaaaag atgatagtgg atttactaat gttgatgaaa
     1621 ttgattggga taacttataa tgaataacta ttctgtgatg attaaaaact cggctaaagc
     1681 tgatttaaag aaaatcaaac agtctaattt gaaacctcaa tttgagaagg ttattcagac
     1741 tttaaaggaa gatccctatc tccctaccca atcatttgag aagttaaaac ctacacatga
     1801 aggtaggtat tctagaagat tgaatagaca acaccgggtt gtttataagg tagatgaaga
     1861 tgaacacgtg gttgaaattt attcagcaag gacgcattac gagtcacagt aattacttgt
     1921 aaatacatta tctcgtggta taatgtattt actaagtaat tacatactgt tagaaatgag
     1981 ggatttaaat gattacaaaa acaagaaaac aaggcaattc aatcatgttg acagtaccta
     2041 aagattttaa tgttcctaat ggagtcgaag ttgaagcaaa gttggtagag aatggtattc
     2101 tttatgaatt tgttgaacca caaaaagaat tttatgattt tagcgaagat attttgtctg
     2161 atataattgc agaaggctac gataaagatg agattcttgt agaatttaag aatagaaaaa
     2221 acaaaatgca ttcttccttt agagatattg ctgaagatac acttactaat tctaaagtaa
     2281 tgactaaaga ggagttggca acagaaattg gcttatgaaa tcgttccttc aaaacatgtc
     2341 attaagtatt taaaaaagct aaaagagaag ccattgaaag aaaaattttt gaatttaatt
     2401 tatgatgaaa ttgcgattga tccatataag ggtgaacaaa aaactgggga tttatcaggt
     2461 atttggtcta gtgggttcaa atatgcgggc acaacatata gagtagctta cgagattata
     2521 gaaaacaagg ttattccagt attgttatgt ggaacgcatg aaaa
//
LOCUS       DAXQKX010000130         2528 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.140, whole genome shotgun sequence.
ACCESSION   DAXQKX010000130 DAXQKX010000000
VERSION     DAXQKX010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.140"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..593
                     /locus_tag="ACF3MF_002803"
     CDS             <1..593
                     /locus_tag="ACF3MF_002803"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HFE3928694.1"
                     /translation="DQEKDVSQLADTNDIGIGQENTDTQKEEQIPDETSEQDSNSVNQ
                     NEYQDNNSSSDNTQIQSPSSSGWGAPVANIIVTSPFGGRADPTGFSGSFHDGIDMGGT
                     SSTPIMASRSGTVVQASFDGSAGNYIIIDHGDGYYSYYLHLSNYIATPGQSVSAGQTI
                     GTMGTTGNSTGVHLHFGIATSSNWSGFVDPAPFLGI"
     gene            748..1284
                     /locus_tag="ACF3MF_002804"
     CDS             748..1284
                     /locus_tag="ACF3MF_002804"
                     /inference="COORDINATES: protein motif:HMM:TIGR01076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HFE3928695.1"
                     /translation="MEDNLKRKGNFDFDSVESISNELVLKAQFKNNDLPIIGGIAIHN
                     VKLSLPIYNGLDNTSLLSGAGTMKPDQQMGKRNYALASHSAKDKTILFFPLEFISLKE
                     KIYVTDLKNIYIYKVSFKEKVDPSRVEVIDDIPNKNMITLVTCGDLAAVTRLIVQGTL
                     IDTVEFKNANQYIHSLFS"
     gene            complement(1606..1812)
                     /locus_tag="ACF3MF_002805"
     CDS             complement(1606..1812)
                     /locus_tag="ACF3MF_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928696.1"
                     /translation="MDGEEYPYKVAFDDLIQLSNLPKDSNMKIAGEFFAPGFLVGLVI
                     SSIATGCFLFLLFLDYIKKTEDIP"
     gene            complement(1822..2097)
                     /locus_tag="ACF3MF_002806"
     CDS             complement(1822..2097)
                     /locus_tag="ACF3MF_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928697.1"
                     /translation="MTNLESRQFDPCWHQIDAQTKELLLGWEENQVVRDFSLNFMMID
                     YYNLATSMQRFPNYGMDIDSFKQKSFSGEIQNEESNNLVIPILYEPG"
     gene            complement(2200..2466)
                     /locus_tag="ACF3MF_002807"
     CDS             complement(2200..2466)
                     /locus_tag="ACF3MF_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HFE3928698.1"
                     /translation="MTSTYASFDKDNLYYDFPSVSGFSSMNNKKYLLMLTRLGYSTSN
                     VRAKRNGGTVITDILLSNQYQVIPNQEIQHQATSGVKIIESEVS"
BASE COUNT          850 a          436 c          430 g          812 t
ORIGIN      
        1 aagatcagga aaaagatgta tcacaactag ccgataccaa tgacatagga ataggtcaag
       61 aaaatactga tacacagaaa gaagaacaga taccagatga aacttcggag caagattcga
      121 actcagttaa tcaaaatgag taccaagaca acaatagttc ttccgataat actcagattc
      181 aaagtcctag ttcttctggt tggggcgcac ccgtagccaa cattatcgtc acaagtccat
      241 ttgggggaag agctgatcct actggatttt ctggatcttt tcacgatggt atagatatgg
      301 gtggaacttc ttcaacgcct atcatggcat caagatcagg aactgtagtg caggcgtcat
      361 ttgatggatc cgcaggtaat tacattatta ttgatcacgg agatggttac tattcatatt
      421 accttcacct aagtaattat attgctacac caggccaatc agtgagtgct ggacagacca
      481 tcggtaccat gggaactaca ggaaattcaa ccggagttca tttgcatttt ggaatagcga
      541 ctagctcaaa ttggtctgga ttcgtagatc ctgctccatt tctaggaatc taaaaatgat
      601 gaaaaaaatc aagcatcttt ctttaaattt acttctaatt agcctttttc ttataggctt
      661 agttttaata tttaatttcc aaattcgatc ttacttactg aataaacaag tccacaatat
      721 gacatagcaa attattcaca gaaagatttg gaagacaatc tgaaaaggaa aggaaacttt
      781 gattttgatt ctgttgaatc tatatcaaat gagttagtat taaaagcaca attcaagaat
      841 aatgatttgc ctataatagg tggtatcgct atacacaatg taaaattatc tttaccaata
      901 tacaacggat tggacaacac ctcgctcctt tctggggctg gaacaatgaa accagatcag
      961 cagatgggaa aacgaaatta cgctttagca agtcatagtg ctaaagataa aactatttta
     1021 tttttcccat tagagtttat ttctctaaaa gaaaaaatat atgtaacaga cttaaagaat
     1081 atttatattt acaaagtgtc ctttaaagaa aaagtggatc catcaagagt cgaagtcatt
     1141 gatgatattc ctaataaaaa tatgatcact cttgttacat gcggagattt ggctgctgta
     1201 acgagattga ttgtacaagg tacactgatc gatacagttg aatttaagaa tgctaatcaa
     1261 tatatccatt ctttatttag ctaatataaa aagtcttatc aatcctgaca gattacgagt
     1321 agtacttttt attaaagaaa gaaggtgctt tctaaattca aattggttta tggtcataat
     1381 aaattaaata gggaaacgaa cgcgattata agttcgtttc tctattttgt atgagtgtct
     1441 ttaatctaat tgaaaagagc cctttttgat ccaacctcaa gaaaattttg aaaaaatctt
     1501 actatggagc taactagtaa cgcacactat ttaatcattt aggaatttgc ttatatcccc
     1561 cttgtcattc tatagtttct agggaagatt tagattgtga ttttcctaag gaatatcctc
     1621 tgttttcttg atataatcca gaaaaagtaa aaataaaaag cacccagttg caatactaga
     1681 gattaccaag cctaccaaga atcctggtgc gaaaaattct ccagcaattt tcatattact
     1741 atcttttggt aagttagaca attgaatcaa atcgtcaaaa gctactttgt aaggatactc
     1801 ttccccgtcc acagtaaaaa cctaacctgg ttcatagaga ataggtataa caagattatt
     1861 gctttcctca ttttgaattt ctccagaaaa gcttttctgt ttgaatgaat ctatgtccat
     1921 accataattc gggaaccgtt gcattgatgt cgccaaatta tagtaatcaa tcatcataaa
     1981 atttaatgag aaatcacgaa ctacttgatt ttcttcccaa cctagcaaca attctttcgt
     2041 ttgagcatca atttgatgcc agcagggatc aaattgtcga ctttccaaat tggtcacata
     2101 gtgcaaatta ttggccaagt tgacgggaaa ataaacataa agtaactcat cttttgttac
     2161 ttctagaacg tcaaatgaaa aagaagcaat atctgaggtt taactcactt cgctttctat
     2221 aatctttaca ccgctagtcg cttgatgctg gatttcttga ttaggaatta cttggtattg
     2281 gttgcttagc aaaatatccg taataactgt accaccattc cgtttagcac ggacgttact
     2341 tgttgagtac cctaatctcg ttaacattag taaatatttt ttattgttca ttgaactaaa
     2401 tcctgatact gaggggaaat catagtagag attgtcttta tcaaaggatg cataagttga
     2461 agtcactttt tttagtggtt cccaatattc ttgatatact tcaaattctg ttagagtttg
     2521 gttgattg
//
LOCUS       DAXQKX010000131         2521 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.141, whole genome shotgun sequence.
ACCESSION   DAXQKX010000131 DAXQKX010000000
VERSION     DAXQKX010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2521)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2521)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2521
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.141"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            4..2376
                     /locus_tag="ACF3MF_002808"
     CDS             4..2376
                     /locus_tag="ACF3MF_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArdC-like ssDNA-binding domain-containing
                     protein"
                     /protein_id="HFE3928699.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQRKTNGQ
                     PMNDKRNGHSWFRQQERIENKVHSLREEIKQQEKQVEKLERQEEIKEMGYNKYGGLDM
                     TIENIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKERSEKGKENLLPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGEFEESKKYQATSEEEKAAVRELLEEA
                     VPTDFLKEKENDHFYRVEFNENDPEKGLKSYGGEIVTFELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VREIEATPEDKKRIESGQIEVIKKTYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTLEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTVETAEQKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNSFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
BASE COUNT         1009 a          395 c          555 g          562 t
ORIGIN      
        1 gacatggcag aagaaaaaga accactagac aatagtcgtt tgggaaaatc caaaagaaaa
       61 ttagtacgat tgcaaaatga attaaacgaa caaattgaaa agatgtttga acaccagaga
      121 aagaccaacg gtcaaccaat gaacgataag agaaatgggc attcttggtt taggcaacaa
      181 gagcgaatcg aaaataaagt gcatagtctg agagaagaga tcaagcaaca agaaaaacaa
      241 gtagaaaaac ttgaaagaca agaagagata aaggaaatgg gctataacaa gtacggcgga
      301 ctggatatga cgatcgagaa tattccaaga atcaaagaag aaatcgaacg ctttgaaaaa
      361 ggtgaatcga ctttttcagc cgctacgatc cgaaaatacc aacggaaatt ggaaacatta
      421 gaacagctga aagaaagatc ggaaaaagga aaagaaaacc ttcttcctga agtacaagca
      481 atcattgaca gcggacgagt gacgcaatgg aaaaaaaatc cgaccattta ttttctgaaa
      541 ggctatcgaa aagtcgcttt agaactgaat gaaaacgggg aatttgagga atctaaaaaa
      601 taccaagcca cgtcggaaga ggaaaaagca gctgttcgtg aattacttga agaggctgta
      661 ccaactgatt ttttgaagga gaaagaaaac gatcattttt atcgagtaga attcaacgaa
      721 aatgatccag aaaaaggatt gaaaagttat ggtggggaga tcgtaacatt cgaattgatc
      781 gatcaactca aaacgttgga taaccaatac gccgcagaag caggttatta taaattctat
      841 tttgaagaag tgaagaacgg agaagtagtc gatcagatcc gaatggatct aggggatggc
      901 gtcaacagta atcaacccat ctatttagag ttagcaaaat tgtgcgaaca agtacctgag
      961 aaggaacaaa aacaatcggt caaaaatgaa cctgtttcga aagaacaaat gcagtcgaaa
     1021 gaaacaaaaa caaaacaaaa gggctatcaa aaacgaacgg cagaagagat taaacaagaa
     1081 gttaaatccc tttcgcaaca ggcactggat gcggtgaaaa agcatactca ttctcctgaa
     1141 gacgtcaaag aacttttgaa ctttatgtct cgttttccag aacgatcctt tagaaatcaa
     1201 ttattgattg aggaacaatt tccaggtgca acggcttgtt taggtcgtgc cgcgttgaaa
     1261 aaagaaggaa tctatatcaa aaaaggggaa caagggaaca agatctttgt cagaaaaacg
     1321 gtcaaaggat tttatgagaa aggacgtggc tttgttcgag aaatagaagc tacaccagaa
     1381 gataaaaaac gaatcgaaag tggtcaaatc gaagtgatca aaaaaactta ctacacgatt
     1441 gaaaaagtgt ttgatatcac acaaacacag ttaaaacctg aagactatcc gaaaatcttt
     1501 ccgaaccgtg tctttgattt tcaattggat aaaaaaggac agtcagaact tcaagctggg
     1561 attcaagcgg tagccaacaa tattggaata caaattcgag atatgacaga aagtgaagtc
     1621 tatcaaagag aattaggaca agcacgtggg gcgtatgttc gtaacgaatt tactggcgaa
     1681 gaagaaatcg tcatgaatac tcgaaatact cctacgcagc atttagctac aagtattcat
     1741 gaattagccc atgcaagaat gcacaaattt tcagaattag ataccgcaac taaagaattg
     1801 caggcagaaa tgacttctta tattgtgtgc aaacattttg gaatggacac gttggagaaa
     1861 gctattcctt atattgcagc atggacgaag aatggtcaga cgttggatga taaggaagct
     1921 gcggaacgtg ggaaaatcat gaatgatgtc agccgtgtcg caaatgaatt cattcaaacc
     1981 atttctaatg aaatcaatca atacagagaa agagaaccag agatccaacc agcagaagtg
     2041 aagcaggagc ataaaaatac tgtagaaacg gcagaacaaa agaatattgt tcctgttggt
     2101 tcactttgga tcgacaagaa agacgggaaa gtaatggaag aagatacggg tcgaacgtta
     2161 catttgaagg atgcggcgtt tattgaagat ccacagcata atcaagtaat tttaaaagga
     2221 aaaagttatg gaaaagagat ccaaacggcg ttaccttcag aagaatttgc gctaggaaat
     2281 tcattccgat tttcacttga gacagtgtca gaagtggcaa aacgaaaaaa tgaaatctat
     2341 tatgaacaac aattgtcaca aaaagaacgt gtataaaaca agtaaaaaag actatctgaa
     2401 aaacggatag tcttttttct tttgggaggt tttaaaatga ccgagaaaaa aatgagtctt
     2461 attgatcgat gtaaacagat cgatatagtg gattttgctc gaaacaatgg aatggctgta
     2521 g
//
LOCUS       DAXQKX010000132         2520 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.142, whole genome shotgun sequence.
ACCESSION   DAXQKX010000132 DAXQKX010000000
VERSION     DAXQKX010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2520
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.142"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(18..716)
                     /locus_tag="ACF3MF_002809"
                     /pseudo
     CDS             complement(18..716)
                     /locus_tag="ACF3MF_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
     gene            795..971
                     /locus_tag="ACF3MF_002810"
                     /pseudo
     CDS             795..971
                     /locus_tag="ACF3MF_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(1147..1716)
                     /locus_tag="ACF3MF_002811"
     CDS             complement(1147..1716)
                     /locus_tag="ACF3MF_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFE3928700.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1790..>2520)
                     /locus_tag="ACF3MF_002812"
     CDS             complement(1790..>2520)
                     /locus_tag="ACF3MF_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928701.1"
                     /translation="FFELFPELLFREEQILPIKEKNYLAILRLSCNQITEKRWKRIEE
                     TQDYRKLTIVTEKLDSLFWLNSEFESESKSKLIKVLYQEWLRYVIGIHDRLIEEVRYY
                     QETLEKFPNSKDKLYQFRLAIQQALAHPAVEWGMLLLKTLQERGYLDVHPPEVKIVFF
                     FRYEHQEARRLAGVLNKTLRHRKRISIHVCTRNKPPRYADLVITDHFFPLDHNEDQKT
                     YLYHPSFGIERLLTDINYWLGKNR"
BASE COUNT          678 a          509 c          449 g          884 t
ORIGIN      
        1 aaagaggggg ggatttttta tcgttgtgga atatttaaat accaacgctt gtcatgaaaa
       61 tcttgtgctc cacccttagt atttccttct ggatcgtttg tcgcacgcat catgacgtat
      121 actttcttat tagggaaatc acgcatattg aaagatacat gatagccaac atttcctaaa
      181 gtattataag cttgatttac gtctggtcta taaatcccat cagctcttac tctagctagt
      241 tcttttccag tattgtagtc cataatgaaa atatactcgt atttataatt agcaatgtgc
      301 catccagcta catgcaagtt tgcgttttcg atttctccga actgatcaat gtgggcgtaa
      361 tttgttccat ctgtcagcgt agaatttgca gcacctgctc gagttggatc aattactggt
      421 ttatcctccg aagtagttgg attatcatcc gtaaaaccat gagccaaatc ataggctagt
      481 ttttctttac ttacacccat ttcagaaaga taaccgtaag gatctgtatg atcgccccaa
      541 atattttgtg ttacccataa atgcgatttg attcctggtt ggttataagg agtgtctaat
      601 gttaatggaa taccatattt cattgctgaa tctcttgcca attcaacgta tactttatag
      661 ttcttttcaa aagtttcttt atcatgtgtg tgttgtaact cgatttgcac aggacttttg
      721 gctcacgagg ttgtcctact ctacatcttg ctgatagata tgccgaaagg aaaacaccaa
      781 cattatgttt tgctttttca gctagaacga gacaagcagg aataccttta gaagatatca
      841 aagatttttt aggtcataaa gatgtttcca ctacacaagt ctatgcccat atttctcccg
      901 aagtgaaaaa aagatcaatg aatcaactag aaaactatat agaagagcaa ataaaaaagc
      961 actcaaattg agtgcttttt taagctcact atcactaaaa ctatcactaa ttttatttat
     1021 aagcgaacat gtttctatca ctgatttttt aaatctagcg aaaaaccctt atcttaaagg
     1081 cgttcgttca attctttggc aaggtcttca aagcctggct tgcctagaag tgcgaacatg
     1141 gttttcttat agctcatgta gaaaaatttt cttgatgatg attttatcca tcaattgaga
     1201 ttgactgttt tgctctccta tgatttcagc tatgattgtc cgattttgcg gttttcttct
     1261 taactggtag ttgattttcc cagtttccat caactcgcta agcatatcca cgactccgcc
     1321 aaatccggtc tttttcgtaa taaaacctag tgctaccatt cgttcatcta gattttttgc
     1381 tgtaatcgtc acaccagtaa tgagcgagtg ctgtaatgtt tgggccagct cttccatccc
     1441 ttcagcattg gatacgacgg aagctgtttt gttaataggt tcttcgttta tttcttttgg
     1501 ttctttcctc tccactttca ctgtttgacg aaggacatct agttcttgca agagcgtttc
     1561 gtattgttct tgggtcagca tcacgccagc tactttttca cgattaaata tatatacgcc
     1621 agttcccgcg tctcgcgctt gagcaaatac atccatcggc gatcgtttca cttctgtgat
     1681 cgaagatgtg ggaacttcta atttctttaa ttccaatgga tttcctcctt tactaatcgc
     1741 tttttattat agcacagact gacttgtttt gatctttttt ccaaaggttt tatcggtttt
     1801 tgcctaacca gtaattgata tcggtaagaa gtctttcgat accaaatgaa ggatggtaca
     1861 gatacgtttt ttgatcttcg ttatggtcta gtggaaaaaa atgatcggtg atcactagat
     1921 ctgcataccg aggcggctta tttcgagtac atacatgtat agagatccgt tttcgatgtc
     1981 ttagcgtttt gttcagtacc ccagcaagtc ttcttgcttc ttggtgttca tagcgaaaaa
     2041 aaaagacgat tttcacttca ggagggtgga catctaaata ccctcgttcc tggagtgttt
     2101 tcagtaaaag catcccccac tctactgcgg ggtgtgcaag tgcttgttgg atcgctagcc
     2161 gaaattgata tagtttatct ttggaattgg gaaatttttc taatgtttcc tgataataac
     2221 gaacttcttc tatcagccgg tcatggatac caattacgta acgaagccat tcttggtaaa
     2281 gtacttttat cagctttgat ttgctttcgc tctcaaattc gctattcagc caaaacagcg
     2341 aatcaagctt ttcagtcaca atcgtcaatt tccgatagtc ttgtgtctct tctatccgtt
     2401 tccaccgctt ttcagtaatc tggttacagc tcaagcgcaa aattgctaga taattttttt
     2461 cttttattgg caaaatctgc tcctctctaa atagcaattc aggaaacaat tcaaagaata
//
LOCUS       DAXQKX010000133         2485 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.143, whole genome shotgun sequence.
ACCESSION   DAXQKX010000133 DAXQKX010000000
VERSION     DAXQKX010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2485
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.143"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..301)
                     /locus_tag="ACF3MF_002813"
     CDS             complement(<1..301)
                     /locus_tag="ACF3MF_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6056 family protein"
                     /protein_id="HFE3928702.1"
                     /translation="MNKHNRKITNNKELILLLIGIWGIFLLFNMYMPTMRADDVVYAS
                     RLDELGYLGASIEHYKTWSSRIIIELFLMFFSKHFMLWKLLNSTIMLGIVVLLCKY"
     gene            394..743
                     /locus_tag="ACF3MF_002814"
                     /pseudo
     CDS             394..743
                     /locus_tag="ACF3MF_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(1015..1305)
                     /locus_tag="ACF3MF_002815"
     CDS             complement(1015..1305)
                     /locus_tag="ACF3MF_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928703.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1513..2205)
                     /locus_tag="ACF3MF_002816"
     CDS             complement(1513..2205)
                     /locus_tag="ACF3MF_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFE3928704.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT          734 a          459 c          349 g          943 t
ORIGIN      
        1 catacttgca aagtaatact acaattccta acataatcgt agaatttaat aatttccata
       61 gcataaagtg tttagaaaag aacattaaga atagttctat aataattctt gaactccatg
      121 tcttataatg ttctatcgaa gcacccaaat agccaagttc atctaatcta cttgcataaa
      181 ctacgtcatc cgctctcata gtcggcatat acatattaaa gagtaaaaag ataccccaaa
      241 tccctattag taacaagatc agttctttgt tattcgttat ttttctatta tgtttgttca
      301 tttttatact ccttcttata tttcctaata gagtataaca tagctttaag cattacttaa
      361 agataactta aaagttatct tttaaatact taattgttaa ataccttatt tgatgcaaaa
      421 gaaatctacg atagtcaaca aaaaaatttt cattatatcc agaaaaattt ttcttagtta
      481 aggacctatg gattgcagta atgcagaatt cgtcgaataa actgccaaag acatacaatc
      541 atattgcttt taaaattgac gaacaagata tagattcgtt tgtctcaaaa atccaaatgt
      601 taggtttaac tgtcgaacca ggacgttctc gtgtgaaagg cgaggcttct tcaatttact
      661 tttacgacta tgataatcac ctcttcgagt tacataccgg tactctccag gaacgtttaa
      721 aatcctacaa ttccactacc tgagactagt aatgactagt ctctttttat ggcctctgat
      781 ccccccattg agcgaatact aatagggctt cgaattgatc tgttcaatct ttaagcaata
      841 tccctcaaat gagtttggaa agtttagtga ttcatcacaa atacttaaat acatgtagtt
      901 atatatagat tgaggttctt gtgagcgtat gctcgtgtgg gttcaaatcc catcgtctgc
      961 atccatcttt ccaaaacaag cggctaggac atttttgtct cagccgcttg ttttctagtt
     1021 tattctttca tcttgtcgga ccttttttct tgggtataga cttttctcat attctaccac
     1081 aattttgggt ttccctaaca catgatagga tctcacaaca aattgctttc tattattata
     1141 ataacctgta acgactaact tcatcccttc gtctacttca gctaggaagt tcaaactatg
     1201 ggaagcaatc aaacaattga ccccatttaa actgaaacgg atcaacggtc tggcactaac
     1261 ttgcaaagta cggatcttat ctactgttcc atattttttc tccataacct tcacctcaat
     1321 accattatac gaacatacat tccctttgta aagaagaaac tctgttttat ctttttgact
     1381 ttttgtctat tacctttctt aaaatcatat tggcacttcc tgcgaagatg aaggacatgt
     1441 actaaaaaaa agaggcagca gtatagatta ctgttgcttc tttactaatt taggtttact
     1501 tgttaagaaa gattatttac gcaaatgttc ttcaacaatt tgctgagatt tatcagctgt
     1561 atcttccact tcatcttttg ctttttctaa cttttgaata tattgtttca agcttgagtt
     1621 ttcagcagtt gcttcgtcta atttcttttg tgtatctgtt aactgagttt ctacatttgt
     1681 tttttcttgt gtcagtgttg cgatttgttg attcaaacca tttacagtat tttgtaattc
     1741 tgaaagtttt gcttgtgctt cttgtagtct tgctgtccaa tctgcattca gatgattgat
     1801 ttcatcattt ttttggttga tctcatctag tttgacattg atttcatttt gtttgctttg
     1861 tagttgtgca tccttgctga ctaattgact ttctaagttt tgtttttctg ctgccgattg
     1921 atttttttgg ttttctaatt catttacttt tgtttggtat tcttggacat ctgcctttga
     1981 atcttgcaat gtctgttctt tttgtgctag tcgagcggta agatctgtaa tcgcttgctc
     2041 tttatctgtc aatgtatgat caagctgtgt cagattctca ttgattgtat caatatctgt
     2101 ctctccaccc cacaaaataa tttcatttgc gtaccgcgtg cctgtgtagc caattagaca
     2161 tagaaatgca acgacaatcc caccagtaat aaatttcttt ttcatttgca tagctcctta
     2221 atccaatact tttacatgct aaaagtaagt gatctcaaac acaatgtcaa gcgtttttaa
     2281 attacatatg taattttaat ataaatacta tcaaatactc atttaatcct ccttttttat
     2341 ctatttaaaa aatctttttt atagagaaaa atgcaggtta atactttctt aaataaatat
     2401 ttatggtgaa caaaaacaaa aaagcaagtt ttattaaacg taaccctttt catttcatag
     2461 attactgtat ttattacaaa aaacg
//
LOCUS       DAXQKX010000134         2398 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.146, whole genome shotgun sequence.
ACCESSION   DAXQKX010000134 DAXQKX010000000
VERSION     DAXQKX010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.146"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            206..2068
                     /locus_tag="ACF3MF_002817"
     CDS             206..2068
                     /locus_tag="ACF3MF_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFE3928705.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2068..>2398
                     /locus_tag="ACF3MF_002818"
     CDS             2068..>2398
                     /locus_tag="ACF3MF_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFE3928706.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          864 a          353 c          466 g          715 t
ORIGIN      
        1 aaaatttgaa aaagcgtttg attatttata ttacgactta gtgcaataaa aaacgctttt
       61 taacagtaca tgtagtcgtc tttataatag ataaactctg taatattagt taaaaagcta
      121 taagttgcac ttagttaagt gcaaacattt catattgtcg ttagtttaga aaacgcttat
      181 attagcaatg taaggagaga tgataatgca gcagctaaca aaaagagaaa ggcagctttt
      241 gatttacttg gtggaaatgt ctgaaccggt aacaatcaaa aagttggctg aaaaagaaaa
      301 tgttagtgtt cggacgataa aatacgatct agatgatata agagagtggc tgaatgagcg
      361 gaagcaagtc ctatatagca aacgtagtca gggaatttgg atgaatatta gtagctctga
      421 tcgaatcaaa ttaaaaagcg aattgatgga tgttaatcgt tttgaaatat ttgcagatca
      481 aagtctccga atcaaacgtt tactaattat gcttttagta acaaaagaag ctattactgg
      541 aatgaaaatg gccaacgcat tagatgtcag caaagatacg atcatgaatg atttagatgt
      601 gctggaaaat aattttctta aggaaggatt gaccttgaat cgtcaggcgc gaaagggttt
      661 ttggatcata ggagaagaac gtctagttcg attaacgatt gaagagattc ttcaaaaaga
      721 gttcacggat tatgacattt ataaattaat gtcattgtta ttgaatggcg gtgagactga
      781 atactttgaa atgtattctg ctactgctac acctatccaa gaggtattta atcaagtaat
      841 cattcgaatg cgacacttac tggaatttga aaatctagag aaactgaatt acgcggaatt
      901 actaaatatt ctgattcgag tgacaattgc taccgttcgc ttacgcaaag aggctacgat
      961 tggtcgttat caattggttg ctgaacaaga attagacaaa aacgatcttt cttatcgcgt
     1021 catgcagcag gtctttgatt attatcagtt gccactgttc gaggatgaat atcattatat
     1081 ctatagtgat acattcgaca cgattcacca gcaagacgtc atgaaactag ttgagaatgt
     1141 gatttataaa gtaagtaaag caatcaacca ttctttttat caagatccac aattgttgac
     1201 gaatctgtat gctcatttat ccatgcgatt atcgagaaag aaaaaatttg tcaatgaata
     1261 taatcctttt aaagaagata tcaagcagaa atacccggaa ttatttgatg cgatcaagca
     1321 agcagttcga caagaaataa gtgaacaaaa tattctgatc aatgattctt tcgtggcata
     1381 tattgcctta cactttttgg tttcctacga aagagaagaa gatctacgaa gcgttagagc
     1441 cgtctacatt tgttcaacag ggttgggtgt gactagtctg atcaagcaaa agatcaatga
     1501 agaattaaat aatatcacta tcgtggcatt tgcttcagta ttgaatgcgc aagaaatgat
     1561 tgctaccaaa gatcctgatt tggtgattag tatttttcca attaatggca tcgatcgtcc
     1621 tttcatcaaa gtccatccat tacccactga acaggacttg aaaaaaattc aacaaataat
     1681 aaaaaaaata cttgcttctt ccaatcagca ggaaaggcat aacttgaatc ttagagaaac
     1741 gtccatcaat aaagatactt tagaagactt tagcaaggaa ttgattttga aagcttatac
     1801 gatttatgaa cgtttacttg tcattttgga agcagaattg atccaagaat atcgagaagc
     1861 ttttttgctt catgtattct taatggttca tcgtatcaca tttgatcaac aatatatggc
     1921 agaaggtcgt caagtagacc agattatttt agacaaagga acactggtag gaaaaatcga
     1981 agcagttttt gcagaaaata atttaggaat caatcagtca gaaatcagtg cattattctc
     2041 atatataaaa gaaggagcgt caagttagtg aaaatgtcag acgaggcttt aaaaattatc
     2101 gaggaaagtc aaaatcggga aaagttaaaa caagtgattg atctaattga agagcgatta
     2161 gtagaacatg ctattgtacc aaccgagttg cagtggacca ttctaattaa tcacttgaat
     2221 gagatgctga aacgttctca aagaaaggaa acgattcccg tagtcgatcg ggatttgttc
     2281 aaagaagtat ccaaagaagc cataactatt tctgatgaaa tagttagaag tatcggtaat
     2341 ttaaccgatg atgaaatata tgttttgtcg attcattttg aaacagcaaa aaataatt
//
LOCUS       DAXQKX010000135         2218 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.147, whole genome shotgun sequence.
ACCESSION   DAXQKX010000135 DAXQKX010000000
VERSION     DAXQKX010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2218)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2218)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2218
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.147"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..860)
                     /locus_tag="ACF3MF_002819"
     CDS             complement(<1..860)
                     /locus_tag="ACF3MF_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HFE3928707.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPYLNGLQM
                     DTSGGTFTLKGTTPSNRYVDSVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAETKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSINFGDYDYSGNPNLLSKLSYDLIE
                     NQNTSAGTLSKGENSFKYNKISAEVEGGVELYYKRRGIANWLPSNKTLVMTVKLRAGA
                     DYSPVDGKLIL"
     gene            complement(884..>2218)
                     /locus_tag="ACF3MF_002820"
     CDS             complement(884..>2218)
                     /locus_tag="ACF3MF_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928708.1"
                     /translation="GVDVYHPQLKVNMSARIVEYTFNVLTNSYDKLVVGNVKTNFLEN
                     TENNVSNLINDAIDQLKNGGEISDLINDIVDHQTDMITGQNGGYVLLDPKEAPSRILI
                     MDTPDKNTARNVLQINNAGIGFSKTGINGTYETAWTLDGGFNASFITAGEIVGITIRG
                     TTLISDGTDYRTSIANGKMTWYSKKVNKDIMELEARDYVSADAGIVSYTMKTGGGFMI
                     RNPQGNLVFSTWDNGNNRPFLSFGAPNFRYSNASYVTSGDGSSLSINGSAGNSWEFKV
                     AGRTMKFTSDGMLTLPGCFFGSWEDGKLARFEQSTVQVYKDFTVRGTKNSTVPTEHYG
                     QRLLNAYETPEYYFADYGEAVTGDDGKVRVDIDPMFAETVNLSRYMTHVTPTELVLCA
                     VTHEDIDHFIIETSKPNVLVRWNLVAHRLGYEDIRLKEDTAYDSTVLDQKRF"
BASE COUNT          659 a          476 c          321 g          762 t
ORIGIN      
        1 agtataagtt ttccgtcaac tggactatag tccgctccag ctctaagctt aacagtcatt
       61 acaagcgttt tattagatgg tagccagtta gctatacctc ttcgtttata atatagctct
      121 actccacctt ccacttcagc tgatatctta ttatatttaa acgagttttc acctttagaa
      181 agtgttccag ctgaagtatt ttgattttca attaagtcgt atgatagctt acttaacaaa
      241 ttaggatttc cactataatc atagtcacca aagttgatgc tgttactgta catcacttgt
      301 aagttaccta acttagaaat ttcttctttc agagcatcta acttgtcttg tagcgtttta
      361 gcttgaccag ttaaatcagt aatctgttga tttaagctat ccactctacc tttagtttca
      421 gccataaaag catcaaaagt ttcattatac tttcgaatca actcttctaa ttgcgaaaca
      481 tattcatcgg cttgaccttg cgaaatgtca gacactccta gtgagaaaaa aatgatatct
      541 tgcgttgtta gaatttgatt gtcttttcta tattctacgt agcagtgttt ataatatcct
      601 gcttcactca taaatgtgcc atcaagagaa aacgtgactt cttcactagt tacgctagtt
      661 gcaacactat ctacgtaacg gttagatggt gttgttcctt ttaaagtaaa tgttccgcca
      721 ctcgtatcca tctgcaagcc atttaaatat ggtttaaccg tcaccgtaat ccctttatca
      781 ccctgacgag ccataatagc tttggtgtag tttaattctt tgctgaaatc taaagccaaa
      841 ttatataaac tgctagccat ttatatacct ccttgtcttc gttttaaaaa cgtttttggt
      901 caagcactgt gctatcatat gctgtatcct cttttaatct aatatcttca taccctagac
      961 ggtgtgccac taaattccat ctaactaata cgtttggctt actagtttca atgatgaaat
     1021 ggtcaatatc ttcatgagta acagcacaca aaactagttc tgtaggtgtc acatgtgtca
     1081 tataccgact tagatttact gtctcagcaa acatggggtc aatatcaaca cgaactttac
     1141 catcgtcacc tgtaacggct tccccataat cagcgaaata atattctgga gtttcataag
     1201 cgttcaatag tcgttgtcca taatgttctg ttggtacagt tgagttttta gtacctctaa
     1261 cagtaaaatc tttatatact tgtaccgttg attgttcaaa cctagcaagt ttcccatctt
     1321 cccatgaacc aaaaaaacaa cctggtaacg ttagcatacc atcactagta aatttcatag
     1381 tcctaccagc taccttaaat tcccatgagt tacccgcact accattaatg cttaaagaac
     1441 taccgtcgcc agaagttaca taactagcat tgctatacct gaaattgggc gcaccaaaag
     1501 atagaaacgg tctgttatta ccattatccc acgtactaaa aaccaagtta ccctgtggat
     1561 ttctaatcat gaaaccacca ccagttttca tggtgtatga tacaataccg gcatcagcac
     1621 ttacataatc acgtgcttct agctccataa tatctttgtt aacttttttt gagtaccaag
     1681 tcattttgcc attagcaata cttgttctat aatcagtgcc atcactaatt aatgtagtac
     1741 ctctaatagt aattcctact atttcaccag ccgtaataaa cgaggcattg aatccgccat
     1801 ctaatgtcca tgcggtttca tatgttccat taatgccagt tttagaaaaa ccaataccag
     1861 cattgttgat ttgtaaaaca ttccttgcgg tattcttatc tggtgtgtcc ataatcaaaa
     1921 tacgactagg cgcttcttta ggatctaata aaacataacc accattttga ccagtaatca
     1981 tatcagtttg atgatctaca atatcattga ttaaatcact gatttcgcca ccatttttca
     2041 attgatcaat ggcatcatta atcaaattgc ttacattatt ctctgtgttt tctaagaagt
     2101 ttgttttgac gtttcctaca actaatttat cgtatgaatt ggttagaaca ttaaacgtat
     2161 attccacaat tctcgctgac atattcactt ttaactgtgg atgatacaca tctactcc
//
LOCUS       DAXQKX010000136         2191 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.148, whole genome shotgun sequence.
ACCESSION   DAXQKX010000136 DAXQKX010000000
VERSION     DAXQKX010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2191
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.148"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..140)
                     /locus_tag="ACF3MF_002821"
     CDS             complement(<1..140)
                     /locus_tag="ACF3MF_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFE3928709.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLV"
     gene            complement(191..>2191)
                     /locus_tag="ACF3MF_002822"
     CDS             complement(191..>2191)
                     /locus_tag="ACF3MF_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFE3928710.1"
                     /translation="GGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSALGEDNAMKVV
                     QSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTIIDALEPVID
                     FLGKMADAFNNLPQPVQDYAVAIGGLTAAFTLLMPIIVGFMALGGPTTLIIGAVITAI
                     AGVIAIIKNWGAITDWFKGIWSKFTDWLGGTWESIKEGASSVWDGVKETWSGFVDWVQ
                     DIWQGVSDWFGELWSGLVEGASNIWQGVQENWQTFVDWVSNIWNGVKEVWSIIWADIV
                     GIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKNTWDTMTQWI
                     SIAWNGIVTTFHTIFDPVVAWWNGIWTSISTTASNIWNSISATASSIWNSIKNTITSL
                     VQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWNSVTSSISNAINAAKSAIQSVWNS
                     ISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIVSDIFNNVKS
                     TIANIWEGIKKTVSAPIDWIRDKISGIFDNLNISIPHIPLPHFKLSGEFNPLKGKIPT
                     LGVDWYAKGSVFNSPNIIGVGEAGPEAVLPLKRSVLQEIGDRILSSTSVSSRAQTIQP
                     VNNYEFNFTIDGNADEVTMKQTTQQIIDSITKVQNDNASAWR"
BASE COUNT          668 a          485 c          333 g          705 t
ORIGIN      
        1 actaagccac ctaaccttcc taaaacagaa gtctcaactc tctgcctttt tggagaaggt
       61 atggttggtc tttccgctaa agccaattta tgcaaataat caggaaatcc atcgattata
      121 gaatgtatac aatcagtcat tttttcacat cctttttaat actaaaaaaa caggagaaat
      181 actctcctgt ttaacgccat gccgaagcat tatcattttg aacttttgta atgctatcaa
      241 tgatttgttg agttgtttgc ttcatagtaa cttcatctgc gttaccatca attgtgaaat
      301 tgaattcgta gttgttcaca ggttgaatcg tttgtgccct agatgaaact gatgtgctac
      361 tcaagatacg atcaccaatt tcttgcagca cagatctttt caaaggtaaa actgcttcag
      421 gtcctgcttc accgacaccg ataatattcg gagaattaaa cacactacct ttcgcatacc
      481 aatcaacacc caacgttggg atttttccct tcaatggatt gaattcccca ctcaatttaa
      541 aatgtggtaa cggaatatgt ggtatcgaaa tattcagatt atcaaagatg ccactgattt
      601 tatctctaat ccaatcaatc ggagcgctaa cagtcttttt gataccttcc caaatgttag
      661 caattgtact tttaacatta ttgaatatgt cggaaacaat acctgttaga ttggaccaac
      721 cgcttgaaat tgcatttttt ccatcgttta ctttggagct aatagtgctt gtaattccat
      781 tccaaagatt caaagcagtg tttttgatac cgttccaaat tccgctgatc cacgaagata
      841 tactattcca aacactttga atggcacttt tagctgcgtt tatagcattg cttatactac
      901 tagtcacact attccagata tttgatgctg tagagctgat tgaattccaa attccaccta
      961 accaactaga tacagttgac caaatatttt gaattactgt agcagctgct tgtaccaagc
     1021 tagtgattgt attcttgata ctgttccaaa tactagaagc tgttgcacta attgaattcc
     1081 aaatatttga agccgtagta ctaatagatg tccatatacc attccaccat gccactactg
     1141 gatcaaatat agtatggaat gtagttacaa ttccgttcca agcgatgctt atccattgtg
     1201 tcatagtatc ccaagtattt ttaaggaaat cagaaatagg tgtccaaaca gcttgccaag
     1261 ctgcgcctaa taactgtcca gctacatcaa aaatacccac gataatatta ataccagctt
     1321 gaatcaatga cgttattaat gtccatggta tttgaacaat tcctacaatg tctgcccaaa
     1381 taatcgacca tacttctttg actccgttcc aaatatttga aacccaatca acgaatgttt
     1441 gccaattttc ttggactcct tgccagatgt tggaagctcc ttcaactaat ccgctccata
     1501 actctccaaa ccaatcggaa actccttgcc aaatatcttg aacccaatct acaaatccag
     1561 accaggtttc tttaactcca tcccaaactg atgaggcacc ttcttttata ctttcccaag
     1621 taccacccaa ccaatcagtg aatttactcc atattccctt aaaccagtca gtaattgcac
     1681 cccagttttt tataattgct ataactccag caatagcagt aataactgct cctattatta
     1741 atgtagtagg accacctaga gccatgaagc caactattat tggcattaat aaagtaaatg
     1801 cagcagtcaa tccgccaatt gctacggcat aatcctgtac tggttgtgga agattattaa
     1861 acgcatcagc catctttcct agaaaatcaa ttactggttc gagtgcatct atgattgtgt
     1921 tgcctatagg agctaatgaa tcctttaatt cagctatttt cccgttcaac tcttgcaacg
     1981 gagtagtaga atcttcattc attttttgtg cagatccact aacatcatca aatgtatggt
     2041 taacatcagt taaagattgg acaactttca tcgcattatc ttcgccaagc gcagaccaaa
     2101 ttgtcgaagc tttatttaat tggtcgtatt gaccatccat attgctaaaa tcttgaatca
     2161 tggaattaat aacgtctttt tgtgttcctc c
//
LOCUS       DAXQKX010000137         2191 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.149, whole genome shotgun sequence.
ACCESSION   DAXQKX010000137 DAXQKX010000000
VERSION     DAXQKX010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2191
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.149"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..140)
                     /locus_tag="ACF3MF_002823"
     CDS             complement(<1..140)
                     /locus_tag="ACF3MF_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFE3928711.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLV"
     gene            complement(191..>2191)
                     /locus_tag="ACF3MF_002824"
     CDS             complement(191..>2191)
                     /locus_tag="ACF3MF_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFE3928712.1"
                     /translation="GGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSALGEDNAMKVV
                     QSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTIIDALEPVID
                     FLGKMADAFNNLPQPVQDYAVAIGGLTAAFTLLMPIIVGFMALGGPTTLIIGAVITAI
                     AGVIAIIKNWGAITDWFKGIWSKFTDWLGGTWESIKEGASSVWDGVKETWSGFVDWVQ
                     EIWQGVSDWFGELWSGLVEGASNIWQGVQETWQAFVDWVSNIWNGVKEVWSIIWADIV
                     GIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKNTWDTMTQWI
                     SIAWNGIVTTFHTIFDPVVAWWNGIWTSISTTASNIWNSISATASSIWNSIKNTITSL
                     VQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWSSVTSSISNAINAAKSAIQSVWNS
                     ISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIVSDIFNNVKS
                     TIANIWEGIKKTVSAPIDWIRDKISSVFDNLNISIPHIPLPHFKLSGEFNPLKGKIPT
                     LGVDWYAKGSVFNSPNIIGVGESGPEAVLPLKRSVLQEIGDRILSSTSVSSRTQAVQP
                     VNNYEFNFTIDGNADEVTMKQTTQQIIDSITKVQNDNASAWR"
BASE COUNT          667 a          479 c          336 g          709 t
ORIGIN      
        1 actaagccac ctaaccttcc taaaacagaa gtttcaactc tctgtctttt tggagaaggt
       61 atggttggtc tttcagctaa agccaattta tgcaaataat caggaaatcc atcgattata
      121 gaatgtatac aatcagtcat tttttcacat cctttttaat actaaaaaaa caggagaaat
      181 actctcctgt ttaacgccat gccgaagcat tatcattttg aacttttgta atgctatcaa
      241 tgatttgttg agttgtttgc ttcatagtga cttcatctgc gttaccatca attgtgaaat
      301 tgaattcgta attgttcaca ggttgaaccg cttgtgtcct agatgaaact gaggtgctac
      361 tcaagatacg atcaccaatt tcttgcagca cagatctttt caaaggtaaa actgcttcag
      421 gtcctgattc acctacaccg ataatatttg gagaattaaa cacactacct ttcgcatacc
      481 aatcaacacc caatgttggg attttcccct tcaatggatt gaattctccg ctcaatttaa
      541 aatgtggtaa cggaatatgt ggtatagaaa tattcaaatt atcaaagaca ctactgattt
      601 tatctctaat ccaatcaatc ggagcgctaa cagtcttttt gataccttcc catatattag
      661 ctatcgtgct tttaacatta ttgaatatgt cggaaacaat acctgttaga ttggaccaac
      721 cgcttgaaat tgcatttttt ccatcgttta ctttagagct aatagtgctt gtaattccat
      781 tccaaagatt caaagcagtg tttttgatac cgttccaaat tccgctgatc cacgaagata
      841 tactattcca aacactttga atggcacttt tagctgcgtt tatagcattg cttatactac
      901 tagtcacgct actccagata tttgatgctg tagagctgat tgaattccaa attccaccta
      961 accaactaga tacagttgac caaatatttt gaattactgt agcagctgct tgtaccaagc
     1021 tagtgattgt attcttgata ctattccaaa tactagaagc tgttgcacta attgagttcc
     1081 aaatatttga agccgtagta ctaatagatg tccatatacc attccaccat gccactactg
     1141 gatcaaatat agtatggaat gtagttacaa ttccattcca agcgatgctt atccattgtg
     1201 tcatagtatc ccaagtattt ttaaggaaat cagaaatagg tgtccaaaca gcttgccaag
     1261 ctgcgcctaa taactgtcca gctacatcaa agatacccac gataatatta ataccagctt
     1321 gaatcaatga cgttattaat gtccatggta tttgaacaat tcctacaatg tctgcccaaa
     1381 taatcgacca tacttctttg actccgttcc aaatatttga aacccaatca acgaatgctt
     1441 gccaagtctc ttggactcct tgccagatgt tggaagctcc ttcaactaat ccgctccata
     1501 actctccaaa ccaatcagaa actccttgcc aaatttcttg aacccaatct acaaatccag
     1561 accaggtttc tttgactcca tcccaaactg atgaggcacc ttcttttatg ctttcccaag
     1621 taccacccaa ccaatcagtg aatttactcc atattccctt aaaccagtca gtaattgcgc
     1681 cccagttttt tataattgct ataactccag caatagcagt aataactgct cctattatta
     1741 atgtagtagg accacctaga gccatgaagc caactattat tggcattaat aaagtaaatg
     1801 cagcagtcaa tccgccaatc gctacggcat aatcctgtac tggttgtgga agattattaa
     1861 acgcatcagc catctttcct agaaaatcaa ttactggttc gagtgcatct atgattgtgt
     1921 tgcctatagg agctaatgaa tcctttaatt cagctatttt tccgtttaat tcttgtaacg
     1981 gagtagtaga atcttcattc attttttgtg cagatccact aacatcatca aatgtatggt
     2041 taacatcagt caaagattgg acaactttca tcgcgttatc ttcgccaagt gcagaccaaa
     2101 ttgtagaagc tttatttaat tggtcgtatt gaccatccat attgctaaaa tcttgaatca
     2161 tggaattaat aacgtctttt tgtgttcctc c
//
LOCUS       DAXQKX010000138         2070 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.150, whole genome shotgun sequence.
ACCESSION   DAXQKX010000138 DAXQKX010000000
VERSION     DAXQKX010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2070
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.150"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(114..356)
                     /locus_tag="ACF3MF_002825"
     CDS             complement(114..356)
                     /locus_tag="ACF3MF_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFE3928713.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(388..945)
                     /locus_tag="ACF3MF_002826"
     CDS             complement(388..945)
                     /locus_tag="ACF3MF_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFE3928714.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(958..1146)
                     /locus_tag="ACF3MF_002827"
     CDS             complement(958..1146)
                     /locus_tag="ACF3MF_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFE3928715.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQTGIVDQFFKS"
     gene            complement(1159..1725)
                     /gene="amaP"
                     /locus_tag="ACF3MF_002828"
     CDS             complement(1159..1725)
                     /gene="amaP"
                     /locus_tag="ACF3MF_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFE3928716.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTRVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
BASE COUNT          583 a          414 c          309 g          764 t
ORIGIN      
        1 tcataaggaa taaagaatac ttcatataaa atatataaaa aagaaccgca gcgagtttcg
       61 ctacggttct caaatttgtt cttcatttca acataagttt ttcttcaatt tgcttataat
      121 ttacgtgcaa agaatgaaac gactaatact aaaatgattg caccgatcaa tgatggaatg
      181 atagccattc ctgcaattgt tggtccccaa gtccctagta aagcttgtcc aattgctgaa
      241 cctactaaac cagcaatgat gtttgcgatg attcccattg atgatccttt attcgtgatt
      301 gctcctgcaa ttgctccaat gataccgccg acgattaatg cccaaataaa tcccatttta
      361 aattcctcct aactgacttc ttacttctta ttgtacacgt ggttcgttat tttctttgac
      421 tttttgtgca cctttgccta cagcagattt tgctttatct gtttggcgtg aagcaaattg
      481 tcctgttgat tttgctgctt ctgttacttt gtcttgtact gtttcttgat ctttttggta
      541 ttcttcttgt gttttgatat ctgcaacatt cacattcact tcgataacat ctaaatgtgt
      601 catattgttt acttcagtac tgattaattc tttgatttgg ttgtaaatat cttcgatgtc
      661 tttaccgtat tctacgatca catctagatc cacagctact tgtttcttac ctacttctgt
      721 attgatacct gctgttacgt tatctgtgtt gactaatttt tcagccatat ttgagaaaaa
      781 tccgccatct aatgtcaata gaccatctac atctttcaat gcataaccga tgattttttg
      841 gatgactttg tcttcataag tcaattcacc attcatcatg cggttttctc ctttttcatt
      901 tgccaaaact gatccatttg ttgtattcat gtttttgttt tccatctttg tttcctccta
      961 tgatttaaaa aattgatcaa ctattcctgt ctgtttcaaa taaaaaccga ttcctgcgcc
     1021 aattgctgtc atgattatga tcaacaatgt cttgaaaaat ccaatcgtta accataaaac
     1081 agctagcagt agtccaagcc ccccaaagat aatagggagc ttgtatgctg aaaatagttc
     1141 tttcattatt tggccctcct attccactcg agagtgcttg tagtctcttg tatcttcttg
     1201 ttcttcataa ccgctgtatg tgactgccac tttgaccgtt tcttttgttc caagtactct
     1261 agtcacttct tcttcgatgt cttgcatcaa tacacctgtt ttccctacta atgaagaagt
     1321 tcgtttcaag tctccgttga catggatatg gattcgattt ttcgttgaac gtatccgtac
     1381 tttaggtgaa tgaatgaact cttcttcgtg taaatgggaa cgtaccaacc cttcgatcgc
     1441 ttttttgtcg attgttagtt tgccatcttc ccgtttcata acgaaagttc ctcttgactt
     1501 tggatagaaa agaacgacta gcaagatgat aatagcaaga acggcaaata ctacagctgc
     1561 ccagaaaata tattgttgca tgtagtaatt cgttaaagta aagaagcgaa atcgttccaa
     1621 ttgttcaggc ataatatacg gcgcattgat caacgcaatc gctagaaata ctgaaagtag
     1681 cagtaaactc atgataacac cgattatttt taacccctta ttcattttcc acctcctata
     1741 aacttatttt taccctgtaa ataactctac cgacaatcac agtatagata gcgaacagtt
     1801 agcatagcat cagtaaataa agcgctacca aacattgctg gatcataacg gcgttttatt
     1861 gccagtctga tactgaaata acaattgctt acttattctc tatttacttt tgattgctgg
     1921 ctatacttaa aggatattat tcaagattaa aaattgcaaa gattatgctc agttattatt
     1981 acaagattct atttatttat taaatttttt cggagaatta aaaaatacaa taaataactt
     2041 tagttacttt atttttatat tatcattttt
//
LOCUS       DAXQKX010000139         1992 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.153, whole genome shotgun sequence.
ACCESSION   DAXQKX010000139 DAXQKX010000000
VERSION     DAXQKX010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1992
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.153"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            127..1851
                     /locus_tag="ACF3MF_002829"
     CDS             127..1851
                     /locus_tag="ACF3MF_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HFE3928717.1"
                     /translation="MKKKLLTLFLVMSFSIVLSVYYNTIVFSEQINYTEEQYNIEKEK
                     ALKVGYSEEQFKQIMEIPTNLSNENSETRIVNYTMTSNQTKVINKAMEQIGKPYEWGA
                     SGPNSFDCGGLVKYVYKQAVNIELPMGTTNQEQYGTEVSLNSLKPGDLLFYGNRGATY
                     HVGIYKGNGVMIHAPQPGETVKEVNIQYFYPNFAKRILPDEPDYPYIDYNKMVTVTKA
                     WSIWNDLQFSHEIKKAIIGDNYKIGKVYTNPENNNKYGEILVSNKVYGYINFYAVKEL
                     TSVQINRYLTSKDSGQPTWGNLECTISKGQTTKDKIYFVKGAYNLGDGKYLYSIYKDQ
                     DSSEWLGYLKAHVSLAYTPIEEINKNVTVTKNWSIWNNLQWEKEIEKPQIGSVFSARL
                     KLTNVSNNAVYYKLYKSGKFYGYINAEAVKDLTTTKLNKYVTFSVNNEDFWSSLDVNY
                     SKGKTERGRVFYISISYNTADNQPIYSVYTDETCTEWRGYYKGNNFEDTQITMLENKS
                     VKVTKSGYTVWGDLNFWTKSGISNTGDIYTTDRKFYNFTNNAYYYELKKDGRVYGYIN
                     SEAAVEMN"
BASE COUNT          781 a          241 c          348 g          622 t
ORIGIN      
        1 agtttgtaac aaacatatat tttttatatt acaatatttc aacaaattaa aaaaaattat
       61 atcttcttaa acaatgataa tattaaaatg caagcgcttg taaaaaataa ggagaagagg
      121 taaaaaatga agaaaaaact attaacttta tttcttgtga tgtctttctc aatcgttttg
      181 agtgtgtact acaatactat tgttttttca gaacaaataa actacacaga agaacagtat
      241 aatatagaaa aagaaaaagc tttaaaagtt ggttatagtg aagaacagtt taagcagatt
      301 atggaaatac ctacaaattt atcaaatgaa aatagtgaaa caagaatagt aaattatact
      361 atgacttcta atcaaaccaa agtcattaat aaagcaatgg agcaaattgg aaagccatac
      421 gaatggggag catcgggacc aaattctttt gactgtggtg gtttagtgaa atatgtttac
      481 aaacaagctg taaatattga actgcctatg ggaaccacca atcaagagca atacggtaca
      541 gaggtaagtt taaattcact taagcctggt gatttattat tttacggcaa tcgaggtgca
      601 acttatcatg taggtatata taaaggtaac ggtgtaatga ttcatgcacc gcaacctgga
      661 gaaactgtaa aagaggttaa catacaatat ttttatccta actttgcaaa aagaattttg
      721 cctgatgaac ctgactaccc ttatattgac tataataaaa tggtaactgt tacaaaagct
      781 tggtcaatat ggaatgattt acaatttagt catgaaatta agaaagctat tattggagat
      841 aattacaaga tagggaaggt ttatactaat ccagaaaata ataataaata tggagaaata
      901 ttagtaagta ataaagtata tggatacatt aatttttatg ctgttaaaga gttgacctct
      961 gttcaaataa acagatattt aacttctaaa gatagtggtc aaccaacttg gggaaatcta
     1021 gagtgtacta taagtaaagg acaaactaca aaagataaaa tatattttgt taaaggagca
     1081 tataatttag gggatggaaa gtatctatat tctatttata aagatcagga ttcctctgaa
     1141 tggttagggt atttaaaagc acatgttagt ttagcctata ctcctattga agaaattaat
     1201 aaaaacgtaa ctgttactaa aaattggtcg atttggaata atctacaatg ggaaaaggaa
     1261 attgaaaagc ctcagattgg ttctgtattt tcagctagat taaagttaac caatgtatcg
     1321 aataatgctg tctattacaa gctttataaa tctggaaaat tttatggtta tatcaatgct
     1381 gaggctgtca aagaccttac aacaacaaag cttaataagt atgttacatt tagtgttaat
     1441 aatgaagatt tttggtcttc tttagatgta aattattcaa aaggaaaaac tgaaagaggc
     1501 cgagtatttt acattagtat ttcatataat accgcagata accaaccgat ttattcagta
     1561 tatacagatg aaacatgtac ggaatggcga gggtattata agggaaacaa ctttgaagac
     1621 actcaaatta ctatgcttga gaataaaagc gtgaaagtaa caaaaagtgg gtatacagta
     1681 tggggagact tgaatttttg gactaagtca ggaatatcga acacaggaga tatatacacc
     1741 actgaccgaa aattttataa ttttaccaac aatgcttact attatgaatt gaaaaaagat
     1801 gggagggtct atggctatat aaatagtgaa gcagctgtag agatgaacta aaatattgct
     1861 gtcccttaat cttatggggc agcaatattt ttatattatt aatcattttt ctgaagcgag
     1921 ggtagaagaa ttaatcaata gtttttcttg ttttgtaata taatagttta attaccaaaa
     1981 attatttaag ta
//
LOCUS       DAXQKX010000140         1924 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.154, whole genome shotgun sequence.
ACCESSION   DAXQKX010000140 DAXQKX010000000
VERSION     DAXQKX010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1924
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.154"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            156..1862
                     /gene="efbA"
                     /locus_tag="ACF3MF_002830"
     CDS             156..1862
                     /gene="efbA"
                     /locus_tag="ACF3MF_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HFE3928718.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
BASE COUNT          687 a          384 c          345 g          508 t
ORIGIN      
        1 acctaaaaat ttggatttca acgatagaaa cactgttttt tatgtaatta gtccaagatt
       61 tttctagact tttgctttac tattcggcca aattggtttt tcttcttttt ttcgttataa
      121 tgaatatact tatgaaaaga aatgaggaat gaaccatgtc ctttgatggt gtatttaccc
      181 acgcgatggt caacgaattg cgtgaaacgt tactatctgg ccggatctcg aaaatccatc
      241 agccttatga aaatgaaatc gtgctggtga ttcgttcacg cggcaaaaac catcgattat
      301 tattatctgc gcacccaagt tatgctcgtg tacagattac ccaaatcgat tatcagaatc
      361 ctgataatcc gcctaacttc gtgatgatgc ttcgaaaata tttggatggc gctattttag
      421 aagacatcga acaaatcgaa aatgatcgag tgatccattt ccactttgct aaacgaaacg
      481 agttgggtga tctacaaaat atcatattga tcgttgaatt aatgggacgt catagtacga
      541 tcgtcttagt taatcgagaa actggaaaaa tactggatgc gatcaaacac attggaagct
      601 ctcaaaacac ttatcgttct ttgcttcctg gtgtagaata tgttgctccg ccaaaacaag
      661 aggtcttgaa cccatttagc tccgagaaag aaaaaatctt tcagcggctt tcccaaactg
      721 aactagatcc aaaagcaatc caacgtcagt ttcagggaat cggtttcgat atcgctcaag
      781 agctgaccaa aagattactg gaacgtccta atgaaaagat ggttgtatgg gacgaatttt
      841 tctcagccat cagccatcag cctattccta ctttttacga aacggaaaat aaagattttt
      901 tcacaccgat tgcttatcag gtattgtccg aacaggcatc tgctgtaaca gcttatccaa
      961 cactcagtca attattagat agctattatc acgaaaaagc agagaaagat cgggcaaaac
     1021 aacaaggcgg agaactgatt cgaaaaatcg aaaatgaact aaaacgaaat aaaaataaat
     1081 tgaaaaaacg tgaacaaaca ctcaaagaat ccgaaaacgc tgagaattac cgtagaaatg
     1141 gcgaactact tactactttt ctgacacaag taccacgcgg cgcaaaagaa gttgttttac
     1201 ctaattatta tgaagaagat cggccaatca aaatagcact agatccggca ttgacaccaa
     1261 atcaaaatgc acagaaatat ttccatcgat accaaaagct gaagaacgct gttaagctga
     1321 ttggcgaaca aatccaagaa gccaaagatg aaatccaata tcttgaatct gtcttatctc
     1381 aactggaaat tgccggccca atggatatcg aagcaattaa agaagaattg acttcagaag
     1441 gatacctgaa aaagaagaac ttaaaaaaac aaaaacgtaa gaaaccatct cagcctgatc
     1501 aatacttttc ttctgacgga acgctcattc ttgttggtaa aaacaatctt caaaatgacc
     1561 agctgacaat gaagacagct aaaaaaaccg actattggct tcatgcaaaa aatatacccg
     1621 gttcgcacgt catcattaaa agtgacaagc cctcagatga aacaattaca gaagctgccg
     1681 agttagctgc ctatttttca aaataccgat actctgccca agtgccggtt gatcttgtac
     1741 aggtaaagca tatccgaaaa ccaaatggcg ccaagcctgg ttatgttatt tatgaaaacc
     1801 aaaagacgat tatcgtgaca ccagaagaag aaaaaattac agctatgaaa caaaacaggt
     1861 aatcaatgag tgtttctaga atcatatttg cgtactttcc cacaacagca attagttata
     1921 aatt
//
LOCUS       DAXQKX010000141         1912 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.155, whole genome shotgun sequence.
ACCESSION   DAXQKX010000141 DAXQKX010000000
VERSION     DAXQKX010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1912
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.155"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..240
                     /locus_tag="ACF3MF_002831"
     CDS             <1..240
                     /locus_tag="ACF3MF_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFE3928719.1"
                     /translation="YNTGKELARVRADGIYRPDVNQAYNTSGNVGYHVSFNMRNFPNK
                     KVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
     gene            355..1563
                     /locus_tag="ACF3MF_002832"
     CDS             355..1563
                     /locus_tag="ACF3MF_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928720.1"
                     /translation="MTAEIGIMNKSGIVLASDSASTIGDSKVYNTAKKLFTLDSMHSV
                     GIMIYGNAEFNGIPWEIIITQYKKSIGSSVFNTLEEYADNFIEFVKTASFIRSEQTEQ
                     EQMIGVFQKIISGLFESIEVDINFLISQGTQIDKDVLVKLLQTKMNTNLSQQSQTFIL
                     DIEKALFLSNYGEILKDILNSISTMEGVSEAISEEIQSYVYEIIIRDDVYSSPTGIVI
                     AGYGRMDIFPKLYSYNMFGFVMNILKYSEYESAQIGNDNGSLRSTILPFAQSDVVNTV
                     VQGVDPQITNYLSSQVDSFDDNGKNTYINIIKNISEFQQNQFIFPLLNMIALLPVEET
                     AIIAETLLNLTSFKRKYTTSVETVGGPIDVLAITPNDGPIWIKRKHYFDIDNNIGYRL
                     RKERANDYNN"
     gene            1547..1717
                     /locus_tag="ACF3MF_002833"
     CDS             1547..1717
                     /locus_tag="ACF3MF_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928721.1"
                     /translation="MITIIKPQEKSPVLKFNESNLAHNKMSITDTVFDVMVEQQKKIN
                     NNNRQRKEINQY"
BASE COUNT          731 a          246 c          326 g          609 t
ORIGIN      
        1 tacaatactg ggaaagaatt agctcgagta agagctgatg gaatttatag accggatgta
       61 aatcaagctt ataatacttc tggaaacgtt ggctatcatg tatcttttaa catgcgcaat
      121 ttccctaata agaaagtata cgtcatgatg cgggcaacga atgatccaga aggaaacact
      181 aaaggcggtg cgcaagattt ccatgacaaa cgttggtatt taaatattcc taaacgataa
      241 aaatagctcc tcgttgagga gcagtacata gaattgaaaa ttaacgttaa atcaaaaaaa
      301 tatttacaag atgtttattt aagtagataa taaaagaaaa aagcaggtga aattgtgaca
      361 gcagaaattg gtattatgaa taaaagtgga atcgtgttag cttcagattc agcatctacg
      421 attggagata gcaaagtata taatactgca aaaaaattat ttactttgga ttccatgcat
      481 tctgtaggta tcatgatata tggtaatgct gaatttaatg gtattccttg ggaaataatc
      541 attactcaat ataagaaaag cattggtagt tctgttttta atactttgga agaatacgcg
      601 gataatttta tagaatttgt caaaacagca tcttttatta gaagtgaaca gaccgagcaa
      661 gaacaaatga ttggggtttt tcaaaaaata atttcaggtt tatttgagag tatagaagta
      721 gatattaact ttttaataag ccaaggtaca caaatagaca aagatgtcct agtgaagtta
      781 ttacaaacaa aaatgaatac caatttgtct caacagtccc agacattcat tttagatatt
      841 gaaaaggcgt tatttcttag taactatgga gaaatattaa aagatattct taatagtatt
      901 tctacaatgg aaggtgtttc agaagctata tcagaggaaa ttcaaagtta cgtttatgaa
      961 attataatta gagacgatgt ttattcttcc cctacaggaa tagttatagc aggatatgga
     1021 agaatggata ttttccctaa actatattct tataatatgt ttggatttgt tatgaatatt
     1081 ctgaaatact cagaatatga aagtgctcaa ataggaaatg acaatggttc attaagatct
     1141 actatattac catttgctca gtctgatgtg gtaaatactg tagttcaagg ggtagatcca
     1201 caaattacta attatctgtc gagtcaagtc gatagttttg acgataacgg aaaaaatacc
     1261 tatattaata ttataaagaa tatttcagag tttcaacaaa atcaattcat atttccgtta
     1321 ctaaacatga ttgctttact cccagttgaa gaaacagcaa ttatcgcaga gactttatta
     1381 aatttaacca gttttaaacg aaaatatact acttctgtag aaacagtagg tggcccaatt
     1441 gatgttttag ctattacacc taatgatggc cctatttgga ttaaaagaaa acattatttt
     1501 gatattgata ataatattgg atacagattg cgaaaggaga gagcgaatga ttacaataat
     1561 taaacctcag gaaaaatccc ctgttttgaa atttaatgag agcaatctag cccataataa
     1621 aatgagtata actgatacag tatttgatgt aatggttgag caacaaaaaa aaattaataa
     1681 taacaataga caaagaaaag aaattaacca atattaatgt tttttctgtt gcgttttttg
     1741 cagtcataat ttaaaacctc gctcaatctt gggcgaggtc tttttttatt tttctgaaaa
     1801 gttaaagtaa ataatagcat aaaataatat attttacaaa gaataagtac aatctagttt
     1861 tttgctatta aatgtgtaat aataaatatg ccatcacaac atgaagaatg aa
//
LOCUS       DAXQKX010000142         1909 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.156, whole genome shotgun sequence.
ACCESSION   DAXQKX010000142 DAXQKX010000000
VERSION     DAXQKX010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1909
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.156"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(291..364)
                     /locus_tag="ACF3MF_002834"
     tRNA            complement(291..364)
                     /locus_tag="ACF3MF_002834"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(328..330),aa:Ile,seq:cat)
     gene            complement(553..1572)
                     /locus_tag="ACF3MF_002835"
     CDS             complement(553..1572)
                     /locus_tag="ACF3MF_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFE3928722.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIY
                     RSDVNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPKR"
     gene            complement(1583..1789)
                     /locus_tag="ACF3MF_002836"
     CDS             complement(1583..1789)
                     /locus_tag="ACF3MF_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HFE3928723.1"
                     /translation="MNNRTFDILKWIAIVVIPALATFVGLVGKGVNWRYTDITVMIIT
                     GFGAFLGSILGVSNRTYKKISSDK"
BASE COUNT          564 a          389 c          324 g          632 t
ORIGIN      
        1 aaatataaaa gagtttaaag cgtaacacac ttatggggaa gtggcttggg gtgcgcttta
       61 aactcttctt tattatcatc tcacaattta acccaaatgt ctttctattt aaaaatcaaa
      121 gtaaaacttt tcaaatatac agaaatataa ctatgtgaaa catcctttca ttaatccata
      181 aaaggataca taaaaaagcc actcatttga gtggcaatga agaaaagctt tagcttgtat
      241 aatactcttc aaaaaattct aacacagaac gattcaaatg gctacgttaa tgtaccctgt
      301 aggactcgaa cctacgaccg gacggttatg agccgtctgc tctgaccaac tgagctaagg
      361 gtactggttg ttgccacata aagccataaa caatcaacca gtagaatgtg tggcaacaaa
      421 cctgttatcg catagcttgg agtgtgacta ttatgggtga tagtgaagat atgcgataac
      481 atcactattt tatcgaatga tttttatagt tgtcaatata gttatgtaat gctcctcaac
      541 gaggagctat ttttatcgtt taggaatatt taaataccaa cgtttgtcat ggaaatcttg
      601 cgcaccgcct ttagtgtttc cctctggatc attcgttgcc cgcatcatga catagacttt
      661 cttattaggg aagttacgca tgttaaaaga tacatgatag ccaacatttc cagaagtatt
      721 ataagcttga tttacatctg atctataaat tccatcagct cttactcgag ctaattcttt
      781 cccagtattg taatccataa tgaagatata ctcgtattta tagttagcaa tgtgccatcc
      841 agctacatgc aaatttgcat tttcgatttc tccaaactga tcaatgtggg cgtaattcgt
      901 tccatctgtc agtgtaggat tagctgcacc agctcgtgtt ggatcaatga caggcttgtt
      961 ttcagaagtt gttggatttt catcggtaaa tccatgagct aaatcatatg ctaatttttc
     1021 tttacttacg cccatttcag aaagataacc gtaaggatct gtatgatcgc cccagatgtt
     1081 ttgtgttacc cataaatgcg atttgattcc cggttggtta taaggagtgt ccaacgttaa
     1141 tggaatacca tatttcattg ctgaatctct agccaattca acgtatgcct tgtagttttt
     1201 ctcaaacgtt gctttatcat gtgtgtgttg taactcaatc tgcacaggac tgttggcatt
     1261 agcatacgaa ccagcaccgt actgtacata accaggttga ccgacttgat aaacaattcc
     1321 gccgtctccc acaatataag cagtataagc gctagtccat gaacgttgca tatactgcgc
     1381 ttcattgcgt cctgttgctg tttcattagc cgtttcatgc agtaaaatat actgattatt
     1441 tgctacttgt gagctacctt catttgcgcc caaattaaat tcattgttga tagtataggc
     1501 aaatccgtta attggcaata aaaaaagagc cgttaacagg ctcatcgcag taatagtaat
     1561 tttctttttc atatctatcc tcctatttat ctgatgaaat tttcttatac gttcgatttg
     1621 atacacctaa aatactccct agaaatgctc caaaacctgt aataatcatc accgttatat
     1681 ctgtgtaccg ccagttaaca ccttttccga caagaccgac aaaagtcgct aaagcgggga
     1741 taactactat agcgatccat ttcaaaatat caaaggttct attgttcata ctatccacct
     1801 cccttcattg gttgggctac tttctttttc aatcgcttgt tttcttctat caatatttct
     1861 ctttctgaaa gcaaggcatc aatttgcccg tccagttgtt caattttat
//
LOCUS       DAXQKX010000143         1896 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.157, whole genome shotgun sequence.
ACCESSION   DAXQKX010000143 DAXQKX010000000
VERSION     DAXQKX010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1896)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1896)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1896
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.157"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..123
                     /locus_tag="ACF3MF_002837"
     CDS             <1..123
                     /locus_tag="ACF3MF_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail adaptor protein"
                     /protein_id="HFE3928724.1"
                     /translation="KFNKDQYFIVIDSMRYNVIYADYDNFYIYFYLESVGEYGD"
     gene            113..514
                     /locus_tag="ACF3MF_002838"
     CDS             113..514
                     /locus_tag="ACF3MF_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928725.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            507..911
                     /locus_tag="ACF3MF_002839"
     CDS             507..911
                     /locus_tag="ACF3MF_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928726.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            923..1531
                     /locus_tag="ACF3MF_002840"
     CDS             923..1531
                     /locus_tag="ACF3MF_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFE3928727.1"
                     /translation="MAKTKTVVTTFDNVSIKRIAFNFKNAGNAIATNCNGQLDGETEM
                     QTVVKKCGATEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDGRIKPGIYSYGPDSV
                     GEDFSLAAEIVDDFEENRKLVGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFG
                     KFYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            1551..>1896
                     /locus_tag="ACF3MF_002841"
     CDS             1551..>1896
                     /locus_tag="ACF3MF_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928728.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKE"
BASE COUNT          702 a          282 c          375 g          537 t
ORIGIN      
        1 aaatttaata aagatcaata ttttatcgta atcgatagta tgcgttacaa cgttatctat
       61 gccgattacg ataattttta tatctatttt tatcttgaaa gtgtgggtga atatggtgat
      121 tgataattct aaagaaaaag aacgtttaaa taagcaaatt tctgctatca aaacttcctt
      181 agaagagcat tttggcctca aactctttca agactccgta ggcgaggatg agctacctga
      241 tgattttaat tacttcattc tcgaaacagg agaaatagaa atgatcactg agccaaaata
      301 tagcgtgggt caaaatctat atctaacttt ctattcagaa aatagagaag atttaacagg
      361 agactcacta gatattattt cattgattca aaatcgttcg attcgttttc agagaatgga
      421 tcccaatcat ttaaaactag agaaccaaga tcgctatatc gatcaattgg tatttacgtt
      481 tagacgatta ttgaagagtg attgtcatgg ctaaaaatag ttgggagcta aaaataaatg
      541 gacatgatga acttcttgtg cggatggaac gctattcaag cgagagcgaa cgactgatta
      601 acgaagcatt gaaatcaaaa ggttcggcta ttgcagtgga taggattaca gaaaaaattc
      661 ctgtttctga agcagattta agaagagggc accaacacgc aaaaaatagt cgtccactta
      721 agactcaata cattaatttg ggtttcatca ttagacctac aagaaaattt gagtatttaa
      781 aatatcctga tttggggata ggtacttcta aaagaaatca gccggacgaa tttatgagaa
      841 gaggattagg tcttgcactt gatccaatta cagaacttct gattcgtcaa ttcgataaat
      901 taaataaata gggggaacaa caatggctaa aacaaaaact gtagtaacaa cgttcgataa
      961 cgtaagtatc aaacgaattg cttttaattt taagaacgca ggaaatgcaa tcgcaacgaa
     1021 ttgtaatgga caattagatg gcgaaacaga aatgcaaacg gtggttaaaa aatgtggagc
     1081 gacagaagta aaatcaaaat ctaaaccaat caatatgacg gtaacaatta ctgcacatgt
     1141 accgatggaa gtttatcgac gtttcaatgg gttgaaacaa gatggacgta ttaaaccagg
     1201 catttactct tacggtcctg attccgtagg cgaagatttc tcacttgctg cagagatcgt
     1261 ggatgacttc gaagaaaata gaaagttagt tggtatgtta gcatgcactt cgaatacagg
     1321 attaacattc tctattgaaa atggtgcgga tgaagtagct gcgttagaac tagaaacaaa
     1381 agttatgcaa gatgaatttg gtaaatttta tcatgaagca attgttgcag aacttgaaga
     1441 agacttaaca gatcaatgga tgacgaatct atctgctgat gtgattaaaa aaacttcagt
     1501 tgtgacaact acggccactc aatcacagta aaaaaaacgg aggtagcgaa atgaacgaag
     1561 attactcaaa aattgaacta aacgatggaa caattttgaa tttagaacct aaactgaata
     1621 tcaagaaatt attgatgatc aatagagatt ttaacacaga cgagtttgca aaaatgactg
     1681 tgggaaaagg atccatggat atttctgtta ttcaaggtgc aaaggctgtg tatattgctt
     1741 accgccaagc gaacatgact gattatattt cattcgatga atttatcgat aaatgggatt
     1801 ttgatatggc tactgccagc tatatttatc aattgatgat gttcaaacaa gcacgcgatg
     1861 cttatcaaaa agaatttgaa aaagcaaata aggaaa
//
LOCUS       DAXQKX010000144         1856 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.158, whole genome shotgun sequence.
ACCESSION   DAXQKX010000144 DAXQKX010000000
VERSION     DAXQKX010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1856
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.158"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            331..945
                     /locus_tag="ACF3MF_002842"
     CDS             331..945
                     /locus_tag="ACF3MF_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFE3928729.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            complement(969..1319)
                     /locus_tag="ACF3MF_002843"
     CDS             complement(969..1319)
                     /locus_tag="ACF3MF_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFE3928730.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(1313..1576)
                     /locus_tag="ACF3MF_002844"
     CDS             complement(1313..1576)
                     /locus_tag="ACF3MF_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HFE3928731.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
BASE COUNT          643 a          318 c          271 g          624 t
ORIGIN      
        1 ataaacttat ttttcattgt ctatcacctc gaaatcaaaa ataagaaaac gttttcttaa
       61 taaatcttaa cagataaatc aagttatata ctagaaaatt cataaaatat atttttaatg
      121 tcataatcgt ttaaattttc ttgattgaca tttatttaca aaaaatattg ccatttaaaa
      181 agaaaagtga cacatactat ttcctccatc attagttttt gtctatataa ggtataccct
      241 aactagacac gaccgcgaca ttgaaaaatc tggttttctc gtgtatgatt agggtgtttt
      301 ttaaatagtt gcagaaagta ggtaaaaatt ttgagagttg catacatacg tgtctcatcc
      361 atcgatcaaa atgaacaacg gcagattgaa gaaatgaaaa aattcggtgc agagagaatt
      421 ttcattgaga aacaatctgg cgcaacgatt actcatcgac ctgtttttca agaagcactg
      481 gatttcgtcc gagatcaaga tatttttatt gtggaagcta ttgatcgact tggaagaaat
      541 tacgacgaga tcatcgcttc agtcaattac ttgaagaaga aaaatgtgca gctgatcatc
      601 acaagtctac cgatcatggc cgaagcaatt ggcaatcctc tcctggataa attcattaaa
      661 gatttgatca ttcaaatttt ggccatgatc gctgaacaag aacgtaccga atctaaacga
      721 cgtcaggcac aaggcattaa gattgcaaaa gcgaacggtg tttataaagg acgtcctaag
      781 ctatacagtg ccaatgcaaa agatccccaa cgtcgtcttg tttataaaaa catcgttgag
      841 gatctaaaaa aaggtgttgc gatcgctaag attgcaaaag actacaatgt tacgagacaa
      901 accgtatata gaataaaaaa agacagcatg gtcaatcacg aatagttgat catgctgctg
      961 tttctatttt atttgcttac tttttgaaaa actgttctaa ctttcatcaa taactcctca
     1021 actaaactat catgcgcttt ttccaaaaaa atacactctc tggcttcata atcaattgtc
     1081 gttagttgat ctaataatac ttttcctgtt gtcttcattt catattctga gtttatattt
     1141 acatatagcg gatagtttct agttgtacta gaaattggag caactgtaac aacgttacta
     1201 taatccgcaa taatatcatg acttaaaaca atataaggtc ttttacctgt ctgttcgtgt
     1261 ccagatcgag gtgctgtatt caataataga atatcgcctt gtctaggttt tctcaccatt
     1321 tttcattacc tactgcttca cctaaatttt gaatcgtcac atgatttctt tcatcagtgt
     1381 aattttcaaa taactgttca attgttaatt cattttctat attagccgct tcgataatta
     1441 gccgcttctg accgtttact tcttcttgta ttatcttcac tttgtcttct gtatgaattc
     1501 caagatattc cataatatac tttggcaatc taaggccatt actatttccc cattttttta
     1561 taggtaacat ttccatagta gacacctctt tctgtatata catagtataa catacataag
     1621 aaaaaacgta tatacttaat tatccttttc tattaaatta gattaacatt ccatgaatcc
     1681 ataaactatg ttaacattta tatgaaaata gtcgaaagga aatcataata tgtttaagaa
     1741 aacaaaatct ttagaatcag gtaagaaaaa aattgatcta aaaataatct cttctggata
     1801 ctttaaagat ttcatagtta ttgatacaaa atggaataaa aaggacatag aaaata
//
LOCUS       DAXQKX010000145         1794 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.159, whole genome shotgun sequence.
ACCESSION   DAXQKX010000145 DAXQKX010000000
VERSION     DAXQKX010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1794
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.159"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..825
                     /locus_tag="ACF3MF_002845"
     CDS             <1..825
                     /locus_tag="ACF3MF_002845"
                     /EC_number="5.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
                     /protein_id="HFE3928732.1"
                     /translation="QEGWKILFKQQTKEEKEDVQTLPLVIIGEHAEVDVKSAEKETQP
                     PKAFTEGTLLTAMKTANKTVDDEEAIKILQEVEGIGTEATRASIIEALKQKEYIQVIK
                     NKLVVTEKGKLLCQAVESQHLLTSAEMTAKWETYLKKIGKREGNQENFINNIKKFIVH
                     LLENVPTDIEKLSFADYQEQKEKEAEKNIVGKCPKCGNNIVLKKSFYGCSNYPECKFT
                     LAEHFRKKKLTKTNVKELLEGKETLVKGIKTKDKKSYNAVVKIGEKGYIDFISFSK"
     gene            941..1174
                     /locus_tag="ACF3MF_002846"
     CDS             941..1174
                     /locus_tag="ACF3MF_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HFE3928733.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMEIRLRSKLKSVLIVQYLKILYNRN"
     gene            1223..1318
                     /locus_tag="ACF3MF_002847"
     CDS             1223..1318
                     /locus_tag="ACF3MF_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031556 - transcriptional attenuation by
                     ribosome [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HFE3928734.1"
                     /translation="MLVFQMRYQMRYVDKTSTVLKQTKNSDYADK"
     gene            1443..>1794
                     /locus_tag="ACF3MF_002848"
     CDS             1443..>1794
                     /locus_tag="ACF3MF_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA adenine N-6-methyltransferase family
                     protein"
                     /protein_id="HFE3928735.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFES"
BASE COUNT          752 a          246 c          324 g          472 t
ORIGIN      
        1 caagaaggtt ggaaaattct tttcaaacaa caaaccaaag aagaaaaaga ggacgttcaa
       61 acgttaccct tggttatcat tggagaacat gccgaggttg acgttaagag tgccgaaaaa
      121 gaaacacaac caccgaaagc ttttacagag ggtacattat taactgctat gaaaaccgct
      181 aataaaacgg ttgatgatga agaagcaatc aagattttac aagaagtcga gggaatcgga
      241 acagaagcga caagagcaag cattattgaa gccttgaaac aaaaagaata tatccaagtc
      301 attaaaaata aacttgttgt gactgaaaaa ggtaaattat tgtgccaggc agtcgaaagt
      361 cagcacctct taacgagtgc tgaaatgacg gctaaatggg aaacgtattt aaagaagatt
      421 ggtaaaagag aaggcaatca agaaaacttt attaataata tcaagaagtt tatcgttcat
      481 ttattggaaa atgtacctac cgatatagag aaattaagtt ttgctgatta ccaggaacag
      541 aaagaaaaag aagcagaaaa aaatattgtt ggaaaatgtc ctaagtgtgg caacaatatt
      601 gtattaaaaa aatcgtttta tggttgttca aattatcctg aatgtaagtt tactttagct
      661 gaacatttta gaaagaaaaa actaaccaaa acaaatgtaa aagaattact agagggaaaa
      721 gaaaccctgg taaaaggaat caaaacgaaa gataaaaagt cctacaatgc cgttgtaaaa
      781 attggagaaa agggatatat tgattttata tctttctcaa aataaacata aaagcccttt
      841 aaatagggct tttatatatt aatcacaaat cacttatcac aaatcacaag tgatttgtga
      901 taaaataaga ataagaagaa atagaaagaa gtgagagatc gtgggaaatt taggcgcaca
      961 gaaagcaaaa cgaaatgata cgccaatcag cgcaaaaaaa gatataatgg gggataagac
     1021 ggttcgtgtt cgtgctgact tgcaccatat cataaaaatc gaaacagcaa agaatggcgg
     1081 aaacgtaaaa gaagttatgg aaataagact tagaagcaaa cttaagagtg tgttgatagt
     1141 gcagtatctt aaaattttgt ataataggaa ttgaagttaa attagatgct aaaaatttgt
     1201 aattaagaag gagggattcg tcatgttggt attccaaatg cgttatcaaa tgcgttatgt
     1261 agataaaaca tctactgttt tgaaacagac taaaaacagt gattacgcag ataaataaat
     1321 acgttagatt aattcctacc agtgactaat cttatgactt tttaaacaga taactaaaat
     1381 tacaaacaaa tcgtttaact tctgtatttg tttatagatg taatcacttc aggagtgata
     1441 acatgaacaa aaatataaaa tattctcaaa actttttaac gagtgaaaaa gtactcaacc
     1501 aaataataaa acaattgaat ttaaaagaaa ccgataccgt ttacgaaatt ggaacaggta
     1561 aagggcattt aacgacgaaa ctggctaaaa taagtaaaca ggtaacgtct attgaattag
     1621 acagtcatct attcaactta tcgtcagaaa aattaaaact gaatactcgt gtcactttaa
     1681 ttcaccaaga tattctacag tttcaattcc ctaacaaaca gaggtataaa attgttggga
     1741 atattcctta ccatttaagc acacaaatta ttaaaaaagt ggtttttgaa agcc
//
LOCUS       DAXQKX010000146         1774 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.160, whole genome shotgun sequence.
ACCESSION   DAXQKX010000146 DAXQKX010000000
VERSION     DAXQKX010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1774)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1774)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1774
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.160"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..1172
                     /locus_tag="ACF3MF_002849"
     CDS             <1..1172
                     /locus_tag="ACF3MF_002849"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: protein motif:HMM:NF012688.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="DNA polymerase A family protein"
                     /protein_id="HFE3928736.1"
                     /translation="EPINLNSTHQMRPALSKAIGKDLPNMDAKKTLKPLKDDYDIIAK
                     LLEYKNIVKLSGTYIDTLPTKQNPTTERWHSRFNPMGTVTGRFSSGKDEEDKTQQGFN
                     VQNQPPEARPMFGPPPGKLLVGADFKAQEIRCVAHLSGEPVLINAFLEERDPYATMAS
                     NFYKRPYEEVYKNADGSDTKERKKMKVAWLATLYGMSDYSLADMLGVGKKEATEFKEE
                     LFGSMPKLSAWLKENEEFVRKNGYVWADLNARKRRLPDAKLPRKNIPYGKWNDPKYDD
                     ARKHNSRINRALRQATNARVQGSSSIQTKVTMIKAHEYCANKPGWALWSTVHDELIFE
                     VPEDFTREEAQDIRDIMLNSYRWGDVVPNGTDIEVMRKWGEGVPVEEWFKNKEAV"
     gene            1174..>1774
                     /locus_tag="ACF3MF_002850"
     CDS             1174..>1774
                     /locus_tag="ACF3MF_002850"
                     /inference="COORDINATES: protein motif:HMM:NF013122.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HFE3928737.1"
                     /translation="MAKTYVVLDLETTGLDYQSEQITEIGAIKIDERFNEIDRFHTMV
                     ALEEGRELPEFITKLTGITAADLEGAPTEAEALEKLNEFIGDSIVVAQNAPFDLSFIS
                     RGGIEPKRFYCTRAMARFVEPELSASLKDVANRHDISLEGHHRALNDVEATIKVFRLY
                     LPHVREEYNEFENIVQDSADRPLKFKPKNAIVRKVHMVAL"
BASE COUNT          533 a          381 c          475 g          385 t
ORIGIN      
        1 acgaaccaat aaatctgaac tcgacccatc agatgcgacc cgcactttcg aaggcaatcg
       61 gcaaggatct cccgaatatg gacgctaaga aaacgctcaa gccgttgaaa gatgactacg
      121 atattattgc gaaactccta gagtacaaga atatcgttaa actgagcgga acgtatatcg
      181 atacgctgcc gacgaagcag aatccgacaa ctgagcgttg gcattcgcga ttcaatccga
      241 tgggaaccgt gacgggccga ttcagctccg gaaaggacga agaggataaa acgcagcaag
      301 ggtttaacgt gcagaaccag ccaccggaag cacgtccgat gttcggtcct cctcccggaa
      361 agctactagt aggcgccgac tttaaagcgc aggaaatcag gtgtgtggcg cacctgtcgg
      421 gcgaaccagt actgattaat gcgtttttag aagaacgcga tccatacgca acgatggcat
      481 cgaacttcta caaacgaccg tacgaggaag tttataagaa cgctgatggt tccgacacaa
      541 aagagcgaaa gaaaatgaag gtcgcatggt tagctacatt atacggaatg agtgattatt
      601 ctctagcgga tatgctaggc gtaggtaaga aagaggcgac cgagtttaaa gaagagttgt
      661 tcggaagtat gccgaagctg tcggcgtggt taaaagagaa cgaagaattt gtgcgaaaaa
      721 acggatacgt ttgggctgat ctgaatgcgc gaaaacgccg gctaccagac gctaagctcc
      781 cgcgcaaaaa cattccgtac ggaaaatgga atgatccgaa atacgatgac gcaaggaaac
      841 ataactcgcg aattaatcgt gctttgcgtc aagcgaccaa tgcacgcgtc caaggatcgt
      901 cgtctatcca aacgaaggtc acgatgatta aagcgcatga atattgcgct aacaaaccgg
      961 gatgggcgct gtggtcaacg gtgcatgacg aactcatttt cgaagttccg gaggatttta
     1021 cgagggaaga agcgcaagac attcgcgata tcatgcttaa ttcttaccgt tggggagacg
     1081 ttgtgccgaa cggtacagat atcgaagtta tgcgcaaatg gggcgaaggt gtgcccgttg
     1141 aagaatggtt taaaaacaag gaggcggttt aatatggcga aaacttacgt tgtactcgac
     1201 ttagaaacga caggactcga ttatcagtcc gaacaaatta cggaaatcgg tgcgattaag
     1261 attgatgaaa gatttaacga aattgatcgc tttcatacga tggttgcgtt agaggaagga
     1321 cgcgagctgc cggaattcat tacgaagctg accggcatca cagcggccga tctcgaaggc
     1381 gcaccgactg aagccgaagc gctcgaaaag ctgaacgaat ttattggcga ctcgatcgtg
     1441 gttgcgcaaa acgctccgtt cgatctgtcg tttatcagtc gaggcggaat agagcctaaa
     1501 cggttttatt gtacgcgagc tatggcacgt tttgttgagc cggaattgtc tgcaagcctt
     1561 aaggacgttg ctaaccgcca tgatatctcg cttgaaggac atcatcgcgc gcttaatgac
     1621 gtagaggcga cgattaaagt attcaggctc tatctaccgc atgtaaggga ggagtataac
     1681 gagttcgaaa acatcgttca agattccgca gaccgtccgc tgaagtttaa gcctaagaac
     1741 gcaattgtac gcaaagttca tatggttgcg ttgg
//
LOCUS       DAXQKX010000147         1729 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.161, whole genome shotgun sequence.
ACCESSION   DAXQKX010000147 DAXQKX010000000
VERSION     DAXQKX010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1729
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.161"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..1221)
                     /gene="tet"
                     /locus_tag="ACF3MF_002851"
     CDS             complement(<1..1221)
                     /gene="tet"
                     /locus_tag="ACF3MF_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008493 - tetracycline transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015904 - tetracycline transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tet(L)/Tet(K)/Tet(45) family tetracycline efflux
                     MFS transporter"
                     /protein_id="HFE3928738.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLL"
     gene            complement(1319..>1729)
                     /locus_tag="ACF3MF_002852"
     CDS             complement(1319..>1729)
                     /locus_tag="ACF3MF_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928739.1"
                     /translation="GLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAP
                     QEYLSRAYNDAPKYCANIVDTQLKNNEVILSGEIPARRIQEYRSDLTFFTNGRSVCLT
                     ELKGYHVTTGEPVCQPRRPNSRIDKVRYMFNKIT"
BASE COUNT          613 a          347 c          262 g          507 t
ORIGIN      
        1 taataaacca cctacaattg caatacctgt tccctctgat aaaaagctgg taaagttaag
       61 caaactcatt ccagcaccag cttcctgctg tttcaagcta cttgaaacaa ttgttgatat
      121 aactgttttg gtgaacgaaa gcccacctaa aacaaatacg attataattg tcatgaacca
      181 tgatgttgtt tctaaaagaa aggaagcagt taaaaagcta acagaaagaa atgtaactcc
      241 gatgtttaac acgtataaag gacctcttct atcaacaagt atcccaccaa tgtagccgaa
      301 aataatgaca ctcattgttc cagggaaaat aattacactt ccgatttcgg cagtacttag
      361 ctggtgaaca tctttcatca tataaggaac catagagaca aaccctgcta ctgttccaaa
      421 tataattccc ccacaaagaa ctccaatcat aaaaggtata tttttcccta atccgggatc
      481 aacaaaagga tctgttactt tcctgatatg ttttacaaat atcaggaatg acagcacgct
      541 aacgataaga aaagaaatgc tatatgatgt tgtaaacaac ataaaaaata caatgcctac
      601 agacattagt ataattcctt tgatatcaaa atgacctttt atccttactt ctttctttaa
      661 taatttcata agaaacggaa cagtgataat tgttatcata ggaatgagta gaagatagga
      721 ccaatgaata taatgggcta tcattccacc aatcgctgga ccgactcctt ctcccatggc
      781 tactatcgat ccaataagac caaatgcttt acccctattt tcctttggaa tatagcgcgc
      841 aactacaacc attacgagtg ctggaaatgc agctgcacca gccccttgaa taaaacgagc
      901 cataataagt aaggaaaaga aagaatggcc aacaaaccca attaccgacc cgaaacaatt
      961 tattataatt ccaaatagga gtaacctttt gatgcctaat tgatcagata gctttccata
     1021 tacagctgtt ccaatggaaa aggttaacat aaaggctgtg ttcacccagt ttgtactcgc
     1081 aggtggttta ttaaaatcat ttgcaatatc aggtaatgag acgttcaaaa ccatttcatt
     1141 taatacgcta aaaaaagata aaacgcaaag ccaaattaaa atttggttgt atttaaccct
     1201 gttacattca ttacacttca taattaattc ctcctttaca ctttaattca aatctttatt
     1261 aaaaaatatt tcatcttatt taacaagaaa ccatatttat ataacaacat aaaatacact
     1321 aagttatttt attgaacata tatcgtactt tatctatccg actatttgga cgacggggct
     1381 ggcaaacagg ttcaccggta gtaacatggt acccttttaa ctctgttaaa caaacactac
     1441 gtccatttgt aaagaaagtt aaatcactac gatattcttg aatacgccga gcagggattt
     1501 ctccactaag aatgacctca ttatttttca attgagtgtc tacgatgttc gcacaatatt
     1561 taggagcatc gttgtatgct cgtgaaagat attcctgtgg cgcataaatt ttaaaactaa
     1621 gatatggctc taacaattct gttccagctt tttttaagac ttgttccaat acaataggag
     1681 caagcatccg aaaatctgct ggggtactaa cagggctata gtataagcc
//
LOCUS       DAXQKX010000148         1695 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.162, whole genome shotgun sequence.
ACCESSION   DAXQKX010000148 DAXQKX010000000
VERSION     DAXQKX010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1695
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.162"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            8..976
                     /locus_tag="ACF3MF_002853"
     CDS             8..976
                     /locus_tag="ACF3MF_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928740.1"
                     /translation="MSYYFEIRIILPEEEKQFLNRKLSKSELSEVTHYLQQKTSRGIP
                     VKFRVGIFRVEDQTKIMSVTLNTKNTKETDVINLLLNRVTDQHVLVYLNEPTEPTLNT
                     QELNRQELKTSNERQEIPQTEIPTETVNEPSVIKEISKKNQAKQTNSRKESLSESITK
                     KNVPKIHLFISILTLFIVLLIGISVIQQVQLQSVKKESELLKEQIERVKETDISQSKI
                     DTFGRYFLTYYFSQEKNQENYQSSLRTYVSEKVDIADWKALEKMLKSVNYYGSEQTKK
                     GYSVEYLLNVSVDNRSKMQKITFEVEPTKNGFLVTTQPKLTDFSFN"
     gene            1005..1373
                     /locus_tag="ACF3MF_002854"
     CDS             1005..1373
                     /locus_tag="ACF3MF_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928741.1"
                     /translation="MGKINLNQIYTAKEMSERIGKNRNYLSQAYRNNKHEILKNFNYR
                     KIGGTIIFSDNPNNDLSQLITAKEASQLLGKNDEYFAHIYKRFPHRLEGIDHIYTGKT
                     LFLTKESLEAFKKKMNGNVR"
     gene            1433..>1695
                     /locus_tag="ACF3MF_002855"
     CDS             1433..>1695
                     /locus_tag="ACF3MF_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HFE3928742.1"
                     /translation="MKKLALLTLFSTALLVSAPLVSFADETASSSDVTILADDNPVVP
                     VEPTDPTTPVDPVDPVDPVDPVDPVDPVDPVDPVDPVDPVDPV"
BASE COUNT          677 a          275 c          276 g          467 t
ORIGIN      
        1 ataacgattg tcttattatt ttgaaatacg aattattctt cccgaagaag aaaaacaatt
       61 tttgaatcga aaattaagta aaagcgaatt atccgaagtc acacactatt tacaacaaaa
      121 gacaagtcga ggaattccag ttaaatttcg tgtaggtatt tttagagtag aagatcaaac
      181 aaaaattatg tctgttacgc tgaatacaaa aaataccaaa gaaacggacg taattaactt
      241 gttattaaat cgagtaacag atcaacacgt tttagtttac ttgaatgaac caacagaacc
      301 aacgcttaat acgcaagaat taaatcgtca ggagttaaaa acgagtaatg aacgccaaga
      361 aataccgcag acagaaattc caactgaaac agtaaatgaa cctagtgtta ttaaggaaat
      421 atcgaaaaag aaccaagcaa aacaaacgaa tagtagaaaa gaatcactat cagaatccat
      481 aaccaagaaa aatgttccca aaattcattt gttcatatct attttgactc tttttattgt
      541 attattgata ggaataagtg ttattcaaca agtacaactt caatcagtca aaaaagagag
      601 cgaattattg aaagaacaaa ttgaacgtgt caaagaaacg gatatttctc aatcgaaaat
      661 agatactttt ggaagatact ttttgactta ctatttttca caggaaaaaa atcaagaaaa
      721 ttatcagtca agtttaagaa catatgtatc cgaaaaggta gatatagctg attggaaagc
      781 gttagagaaa atgcttaaga gtgtcaatta ctatggtagt gaacaaacaa aaaaagggta
      841 tagcgttgaa taccttctaa atgtttcagt agacaatcgt agtaaaatgc aaaaaatcac
      901 ttttgaggtt gaaccaacta aaaacggctt tcttgtgaca actcaaccaa aacttacaga
      961 cttctctttt aactgaaata cgctaaaaag agagtgctta aacaatggga aaaattaatt
     1021 taaatcaaat ttacacagca aaagaaatga gtgaacggat aggtaagaat agaaattacc
     1081 tatcccaagc ttaccgtaac aacaaacatg aaatacttaa aaattttaat tatcgaaaaa
     1141 ttggtggaac aattattttc tctgataatc ccaataatga tttatcgcaa ttgattacag
     1201 caaaagaagc aagtcagttg ttaggaaaga atgatgaata ctttgcccac atttataaac
     1261 ggtttcctca tagactagag ggaatcgatc acatttatac aggtaaaaca ttattcttaa
     1321 cgaaagaatc gctagaagct tttaaaaaaa agatgaatgg aaatgtcaga taaagcatat
     1381 ttatgatata ctatttatgt acacaaatac taatttttaa ggagattata aaatgaaaaa
     1441 attagccctc ttaacactat tcagcactgc attattagta tcagcaccgc ttgtcagttt
     1501 tgcagacgaa accgcaagta gcagtgatgt tactatctta gccgatgata atccagtcgt
     1561 tccagtagaa ccgacagacc cgactactcc agttgatcca gttgatccag ttgatccagt
     1621 cgatccagtc gatccagttg atccagttga tccagttgat ccagtcgatc cagttgatcc
     1681 agtcgatcca gtcga
//
LOCUS       DAXQKX010000149         1643 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.163, whole genome shotgun sequence.
ACCESSION   DAXQKX010000149 DAXQKX010000000
VERSION     DAXQKX010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1643
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.163"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            528..1082
                     /locus_tag="ACF3MF_002856"
     CDS             528..1082
                     /locus_tag="ACF3MF_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFE3928743.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGG"
     gene            1138..>1643
                     /locus_tag="ACF3MF_002857"
     CDS             1138..>1643
                     /locus_tag="ACF3MF_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928744.1"
                     /translation="MKITEFSEVFKTFSNIYNRIPEIEQNVVVDNDYYIENDFNKPRK
                     YDNLYNFIHNRTTINNNSNTRVLINSAYFHIKYLKKYEYEEVVLDYGLNRQSFLIYAI
                     NNGNLPSNKKNIIIETYAYLEGGSKKLIKSCNIEYQLSVGEIKCVFEEDLELDLKKIF
                     ASIHDYIG"
BASE COUNT          658 a          182 c          281 g          522 t
ORIGIN      
        1 tttcaacagg ccgaaggcga acttgaacaa atgctaagcc aactgattga gaattagaaa
       61 caatctgcag tagggaagaa tcatttacac aaaattattg acgctcccca aaattatgat
      121 cttgcgtaaa gttataaaat attaataaaa atattttatt aatgaaaagc ttggtagcac
      181 ggttattcat atgctaattt atttcacttt atagtaaggg gagttcttag tatattgttc
      241 aaacttaaat ttcatataat ttaattatgt aaattagcta ttctaagaac ttctacggat
      301 aactgcccgt ctaaaattta aataagagct tagaatcttc atataagtaa ggttaatttt
      361 tttgtacaaa aaagtcggaa tattctgagt tactgaaatg atataaaatc ataaactaaa
      421 ccccttgatt ttcttcactt ttaacagagt atatatataa gttcatgatt atggtaaaat
      481 atatatataa tcatgaactc agaatatttt taagaaggga aacaatagtg agctataatg
      541 tacaaccgtt aaggacaaat gaagagatac aagattttca gttttggcta agaagaacaa
      601 gtaatccaga aagagatagt tttttatttt tgtttggaat caataatggg ttacgtatgt
      661 cagatattat aggattaaaa gttggagaca tacgaggtaa aagtaagcct attattgttg
      721 aacataaaac aggtaagcga aaaccgattt ttatagataa tttgagagaa gagattttat
      781 tatatactga aggtaaagaa gaaaatgatt ggttatttcc aagtcggcaa caaggtcgac
      841 atataacaag ggatcgtgtc tatcagatat atgcagatat agcagaaaaa ttaggaagag
      901 atgatatagg aacacataca ttaagaaaaa cttttgggta tcactactac aagaaaacta
      961 gagacattgc taccttaatg tttattttta atcatagctc gcaagcaatt acaaaaaggt
     1021 acattggtat aactgaagat gaaatagggg catcgttacg tggttttaaa ttgggaggct
     1081 aattgagata ttaggatata ttttttgtgt ataatgaaaa cttagaaggt gagattaatg
     1141 aagataactg aattttcgga agtatttaaa acgtttagta acatttacaa tagaatacca
     1201 gagatagaac aaaatgttgt agttgataat gattattata tagagaatga ttttaataaa
     1261 ccaagaaaat atgacaacct atacaatttt atacacaata gaacaacaat aaataacaac
     1321 agtaacactc gagttttgat taattcagca tattttcata ttaaatattt aaagaaatat
     1381 gagtatgaag aagttgtatt agattatggg ctaaatagac agtcattttt aatttatgca
     1441 ataaataacg gaaatttgcc aagcaataaa aagaacataa ttattgaaac atatgcctat
     1501 ctggaggggg gatctaaaaa actaattaag tcatgtaata tagagtatca attatcagta
     1561 ggagaaatta aatgtgtttt cgaagaagat ttagaacttg acttaaaaaa aatttttgcc
     1621 agcattcatg attatatagg ttt
//
LOCUS       DAXQKX010000150         1608 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.164, whole genome shotgun sequence.
ACCESSION   DAXQKX010000150 DAXQKX010000000
VERSION     DAXQKX010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1608
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.164"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(52..507)
                     /gene="tnpA"
                     /locus_tag="ACF3MF_002858"
     CDS             complement(52..507)
                     /gene="tnpA"
                     /locus_tag="ACF3MF_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HFE3928745.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            750..1608
                     /locus_tag="ACF3MF_002859"
                     /pseudo
     CDS             750..1608
                     /locus_tag="ACF3MF_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEfa10 family transposase"
BASE COUNT          522 a          307 c          305 g          474 t
ORIGIN      
        1 ggggattttt aaaagaccgc caactgctca tcttcactca cttacttctc tttatttttt
       61 aaatggttct acgtactctc ttttacttat aatatatcga atgcgatcat cagcttcttg
      121 ttcacggatg tatttttcat ttgtcttttg attcaatccg actgtactca catagtatct
      181 cttcgaccaa aaggatttgt ttccgtattt atatttgaga tttgcgtgct gctcgtggat
      241 tagtaccgca ctacgacctt tcagataccc cataaaactg gatatacata tttttggtgg
      301 tactcgaaca agcatgtgaa tatgatctag cattgcatgt gcttctatga tttccacatc
      361 tttcatttcg cacaacttcc taagtatttt tccaagatct tttcgtaatt gcccatagat
      421 tacttttcgt tgatattttg gtgtaaaaat aatatgatac ttacaattcc aacgagtata
      481 tgctaaactt ttatcgtcat ttgacatgaa aaaactcctt tcgatctgat gagcggttgg
      541 tagccactca ctagtatatc gaaaggagtt tttatcgcta aagatacttc ttccacgcgt
      601 agaaacgcgc ggttttcttg tttcgcacgc tttacgcaca aaactgactg aagtcattaa
      661 gaaaataaaa gggtctaaaa cttttaagtt ttgtaccgac ccccaaaagt tagaccaaaa
      721 aatctaactt ttggaggtcg gtatttttta tggctaagta tacttttgaa cttaaattaa
      781 agatcgttca tgattacttg gatggtaaag gcggaagtga ttatctggca aagaaatatt
      841 ccattaaggc tccatcacaa gtgaagcgct ggatcaatgc ctatcaagaa tttggtgaag
      901 agggtctagt aagaaagcga caaaagaaaa aatattctgt tcaatttaag ctggatgcga
      961 tagagttata tctaacaagt gagctgtcct atcgtgaagt tgccaacaca cttaacatga
     1021 acaaccctaa tttgatcgct agttggatgc gtcaattccg tgagggtggg atcgatggac
     1081 tctcaaaaac gaaaggatgt ccacctatct tgtctaagaa aaatgaaccc aaaaataaga
     1141 aaaaatctac aactaaagca acgtctaaag aacgtgaacg catcgaggag ttggagaaac
     1201 gagtccgttc ccttcaaatt gaaaatgcct ttttaaaaga attgaggaag ctgcgaaaac
     1261 aggaagccca acaacgacga atgaagcaat cgcacgaatc atcgcaagcc tccgaggacc
     1321 gtttaaatta gttgagcttc tagaaacttt aaagttccct aaggcaatct ttatgtactg
     1381 gcaaaaacga ttggaccgta aaaatccaga tcaagagatt gaagcggaaa tgcttaaagt
     1441 tcgggagaag cacaaggatt atggctgttt acggatgacc aatgaactaa gaaaccgcgg
     1501 tttctctatc aataaaaaga aagttcagcg cctgatcaag aagctaggaa taaaagtaac
     1561 gacatacaca cgtaaatcac ggcgctacaa ttcttatcga ggacaagt
//
LOCUS       DAXQKX010000151         1586 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.165, whole genome shotgun sequence.
ACCESSION   DAXQKX010000151 DAXQKX010000000
VERSION     DAXQKX010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1586
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.165"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            294..1481
                     /locus_tag="ACF3MF_002860"
     CDS             294..1481
                     /locus_tag="ACF3MF_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFE3928746.1"
                     /translation="MYFLGIDIGKRTHVASIMNEEGKVLLKGFSFPNTTEGAESLIER
                     MVDYSGAPSDFVIGMEATGHYWLSIFSYLHESDYLIHVVNPLQTDGWRKGTEIRKRKN
                     DIIDSVLIADLMRYGSFVETVLSDENVFSLKQLSRYRTYLVGTASDFKRKIIAVLDQV
                     FPEYATIFTKQGVFGKASKELLLAFSAPIDLENISSETLAQYLAELSRNRIKAEKADQ
                     LKQAASNSFGVKFAQEAFTFQLRSMIEQLKFIESQIKETEREIKHIMDTLNSVILTIP
                     GIGPINGATILGEIGDIQKFSNPKKLVAYAGIDASVTQSGQYEATHNVMSKRGSPYLR
                     KALFSAALVASQCDPVFSAFYQKKVSEGKHHLTALGAVSRKLCYVIHAILTKNEPYII
                     VSD"
BASE COUNT          467 a          295 c          318 g          506 t
ORIGIN      
        1 ggttttaacc ttccggtttt gattggataa ccctatgaac catcgttatt ttaatttggt
       61 attaactcat ttcttttgag ataatatatt tattggattg agaggctaag ccgttccccc
      121 cttgggtcat tgaacccgca ctcgagagac tggctcctct ctctgataag tggattgcgt
      181 atgagttaga tgttgaaagt ccttacttta ctccgtatct cgtacaaggt agtgacgctt
      241 ttcagttgag tggatttcaa tccaaaattc tttttttgaa aggtcagata tacatgtact
      301 ttttaggcat tgatatcggt aaacgcactc acgttgcttc tatcatgaac gaggaaggaa
      361 aggtattact aaaaggtttt tcatttccta acaccactga aggagcagag tcattaattg
      421 agcgaatggt cgactattcc ggagcaccca gtgactttgt tatagggatg gaagccacgg
      481 ggcactattg gctgtccatc ttttcatacc ttcacgaatc agattatttg attcacgttg
      541 tgaatcccct tcaaacagac ggatggcgta aaggtacaga aatacggaaa cgaaaaaacg
      601 atattattga ttctgttttg attgctgact taatgcgcta tggctcattt gtcgaaacgg
      661 tcttatccga tgaaaatgtt ttttctttga aacaactttc tcgttaccga acttatttag
      721 taggtacagc gagcgacttc aaaagaaaaa ttatagccgt attggatcaa gtctttccag
      781 aatacgcgac gatttttacc aagcagggcg ttttcggaaa agcttctaaa gagttattgc
      841 tggcgtttag tgccccgatc gacttagaaa acatttcctc agaaactttg gcccaatact
      901 tagctgagtt aagcaggaac cgaatcaagg cagaaaaagc ggaccaattg aagcaagcag
      961 cttctaactc ctttggagta aaatttgctc aagaagcgtt caccttccaa ctacgttcaa
     1021 tgattgaaca attaaaattc attgaaagcc aaataaagga aacggaaaga gaaatcaagc
     1081 acataatgga cactttaaat tctgttattc tcacaattcc tggaattggt cctataaacg
     1141 gtgcgactat tcttggtgag atcggagata ttcaaaaatt ttctaacccg aaaaaactcg
     1201 ttgcttacgc tgggatagac gcttccgtga cacaatcagg gcaatatgag gcaacgcata
     1261 atgttatgag taaacgaggg tctccatatt tgcgaaaagc cttgttttcg gcggctttag
     1321 tagcttctca atgtgatcct gtttttagtg cgttttacca gaaaaaagtt tccgaaggaa
     1381 aacatcatct aactgcctta ggtgcggttt ctcgtaagct ttgttacgtg attcatgcta
     1441 ttttgactaa aaacgagcct tatataattg tttctgatta gctattgaac attcaaaaaa
     1501 actaatggta agaagcttat ttgttgtacc cttttttcgg aattatctgt tataaaatat
     1561 tttttgattt ggctaatttt tacttg
//
LOCUS       DAXQKX010000152         1483 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.166, whole genome shotgun sequence.
ACCESSION   DAXQKX010000152 DAXQKX010000000
VERSION     DAXQKX010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1483
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.166"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            336..728
                     /locus_tag="ACF3MF_002861"
     CDS             336..728
                     /locus_tag="ACF3MF_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFE3928747.1"
                     /translation="MNKQYEMVRDFQHKFGQPVADKPTVLSEDRRNERYEYMEEELTE
                     FLFAKTVVDQADAMIDLIYLATGTLVELGVKPEKLFEIVHNANMSKLWPDGKAHTNPE
                     NGKIIKPPTFVSPEPLLKDEISRQTEEC"
     gene            745..1236
                     /locus_tag="ACF3MF_002862"
     CDS             745..1236
                     /locus_tag="ACF3MF_002862"
                     /inference="COORDINATES: protein motif:HMM:NF013043.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HFE3928748.1"
                     /translation="MSREIVASGGHLFVVDEDDFAMISKYRWFKDSKGYAIANTPRIK
                     GKKTTVKMHRLITGAKIGEVVDHINGDPADNRKINLRITTQSQNTKNVTTRRQNNASG
                     YKGVSWDRKKKKWMAKITVNYRAIYLGRHESKVDAAKAYNEAAIKYFGEYARLNDLPK
                     EGA"
     gene            1237..1458
                     /locus_tag="ACF3MF_002863"
     CDS             1237..1458
                     /locus_tag="ACF3MF_002863"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928749.1"
                     /translation="MTQIYACFLNGKLYGCGDIEYMNDLFRDYVVYCEMYGRDDCTFR
                     ITTKEKARRLVISETIRENGEALKRLEDE"
BASE COUNT          510 a          270 c          361 g          342 t
ORIGIN      
        1 agattcggat ttttatttcg gcgaataagc gtccattctt cggaatagat acgcatctat
       61 ttatgaagac gctgtgccaa gcgaaaggta atgcgcagtt atatacgaaa ggaaattatc
      121 cggcgatgtc gcaaaaatgg cgattaccta cccgttatat aagtgaggag gtcatcgcat
      181 atgaaacgac ttatcagcgc cacagcaacg atcatcgccg gactactttt cgtcctgccg
      241 tacatccata cgataggatt ccggtggttt tcgatagtgg ccgcgttcgc cttgattgcg
      301 atattaacga acgaaagtac gaaggaggaa acgaaatgaa taaacaatac gaaatggtgc
      361 gtgattttca acataagttc ggccagccgg tcgcagataa gccgacagtt ctaagcgaag
      421 atagacggaa tgaaagatac gaatacatgg aggaagaatt aacggaattt ctttttgcga
      481 aaacagtcgt agaccaggcg gatgcaatga tcgatcttat ttatctcgca acagggacgt
      541 tggtggaact cggagtcaag cctgaaaaac ttttcgaaat tgttcataac gcgaacatgt
      601 cgaaactgtg gccggatggt aaagctcata cgaatccaga gaacggaaag atcattaaac
      661 cgcccacatt tgtaagccct gagccattac ttaaggacga gatttcgaga caaaccgaag
      721 agtgttagga ggactctaaa gtgtatgagt agagaaatag tagcttcagg aggacaccta
      781 tttgttgttg atgaagatga tttcgctatg atatctaagt acagatggtt caaggactca
      841 aagggatatg caatcgccaa tactcctaga ataaaaggaa aaaagacaac agtaaaaatg
      901 catagattga ttaccggagc caagatagga gaagtcgttg atcatattaa tggagacccc
      961 gctgacaatc gtaaaataaa cctaagaata accactcaat cccaaaatac aaagaacgtc
     1021 accacaagga ggcaaaataa tgcctcaggg tataaaggcg ttagttggga tcgcaagaaa
     1081 aagaagtgga tggcgaaaat tacggttaac tatagagcta tttatcttgg gagacatgaa
     1141 agcaaggttg atgctgctaa ggcatataat gaagccgcaa taaagtattt tggagagtac
     1201 gcgagactga atgacctacc taaggaaggt gcttagatga cgcaaatata tgcgtgcttt
     1261 ctgaacggta agttgtacgg atgcggcgac atcgagtata tgaacgacct attccgcgat
     1321 tacgttgttt attgcgaaat gtacggaaga gatgactgca cgttccgaat aactacgaaa
     1381 gagaaagctc gcagattagt gattagcgaa actattcgcg aaaacggcga agcattaaaa
     1441 cgattggagg acgaataaat ggcggaaacc aaaatgaacg tac
//
LOCUS       DAXQKX010000153         1462 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.167, whole genome shotgun sequence.
ACCESSION   DAXQKX010000153 DAXQKX010000000
VERSION     DAXQKX010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1462
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.167"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            103..1398
                     /locus_tag="ACF3MF_002864"
     CDS             103..1398
                     /locus_tag="ACF3MF_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFE3928750.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFKLRIMIRHGKTFLTK"
BASE COUNT          460 a          289 c          271 g          442 t
ORIGIN      
        1 tggtgaactt caccaacatc ttttttgtat aaaaaaatat agaaaagaca ccctgaaatc
       61 ctttagaatt aatttggcta ccaattcata ggaggattca agatgtctca tactcagctt
      121 atcaaagata ccctaaatat tctagaccta aatatctatt tcgaggaaaa ttgtttaact
      181 aaagaaaaat acaaagggca aatttgcttg atttacaaag gaactcttct gtacaagcca
      241 gaagagtgtt cccattgtct ttgtgtcgtc ccctctagga tcattcgttg ggggacgaca
      301 accgttcggt tgttactgaa tgatgtgtct gagtatcgca cttatctgga gctgaagaaa
      361 caacgattta aatgtaagtc ttgccaaaga acattcgtag cggatacctc tgttgctgaa
      421 aaacactgtt tcattagtca aaaagttcgt tggtctgtca ttgctcgctt aaaagagaat
      481 acttccatga cggaaatcgc tcgtcagaaa aatatttcca cttcttcggt ctatcgtgtc
      541 atgaagcgat tctaccgccc attgaatcct ttcaaacaga ctttgccaaa ggtcttatgc
      601 tttgatgaat tcaaatcggt tcgaagtgtt gccagtgcaa tgagttttat catgatggac
      661 ggacaaagcc atgcattatt ggatattgtc gaaaatcgac gcttgcctta tttagaacgc
      721 tatttttctc ggttttcatt agcgactcgt gaagccgttc aattgattgt tattgatatg
      781 tatgcgcctt atgtttcgtt ggtgaaaaag cttttcccga atgctcagtt gatcatcgat
      841 cgtttccaca tcgtccaaca tattggcaga actttcttga atcatcgagt gaaagaaacc
      901 acggtacgac ttaaaggaaa ttcccactct caacgagggt tagggaaaaa attgaagcgc
      961 tattggaaac tcctacaaaa agaagaagca aagttaaact atgaaaaacg ggtttggcgt
     1021 gccagtttta aagattattt gactgaaagt gagattgccg atcgactgtt agctgcttgt
     1081 cccaacttac gccaaggcta tcagttatac caagacattc tttatgcggt aaagaaaaga
     1141 gatcagtcac tatttgagga ttgtttaact agagacatta gcggtctgcc agaaacctat
     1201 acaaccactt tacgaacgtt taaaaagttt ctgccacaga tccaaaatgc gcttcactac
     1261 agctattcaa acggaccatt ggaatgctta aacaaccaca tcaaagtatt aaaacgcaat
     1321 gcgtacggct ttcgcaactt ttacaatttc aaactacgaa ttatgattcg tcatggcaaa
     1381 acatttttaa ccaaataaac agaacagaaa gaggttttct tctttctgtt ctgtccaaat
     1441 tattctaaga tttctcttta cc
//
LOCUS       DAXQKX010000154         1455 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.168, whole genome shotgun sequence.
ACCESSION   DAXQKX010000154 DAXQKX010000000
VERSION     DAXQKX010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1455
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.168"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..1039
                     /locus_tag="ACF3MF_002865"
     CDS             <1..1039
                     /locus_tag="ACF3MF_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HFE3928751.1"
                     /translation="EINQKYDETLKNVYSSLIVSNIEETSSSEIKNKLSLLKLKEKEY
                     IIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGLLNKLTISNIDSTREKIIKIFDKI
                     NNLFKNDNAELRKGLLEFKLQELELHYSYLVKITEEKEQQKAIKEQMIEEEKVRREID
                     REKKRIDKEQRQFNSEISKLIAYMQKANADVEKELYANKIQELEEKLKELEVIRENVL
                     QRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEPMDRIKELSSASVPFEFDVHAMIF
                     SEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLDEIEKVVLENYNGTVTFTKLAKAE
                     QYRRSLELSKD"
     gene            1111..>1455
                     /locus_tag="ACF3MF_002866"
     CDS             1111..>1455
                     /locus_tag="ACF3MF_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928752.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQD"
BASE COUNT          639 a          169 c          227 g          420 t
ORIGIN      
        1 tgaaataaat caaaagtatg atgaaacatt aaaaaatgtc tattcttcac ttatcgtttc
       61 aaatatagaa gaaacttcat cttctgaaat aaaaaataag ctttctttgt taaaattaaa
      121 agaaaaggaa tatattattg acgatgctgt ttctgtccct cttattttaa ataaacgaga
      181 gaaaaataat ttaaagaaaa aaatgctcat tccatttgat tcagaagtga aaggattact
      241 caataaacta actatttcta atatagactc gactagggaa aaaatcataa aaatatttga
      301 taaaattaat aatttattca agaatgacaa tgctgaatta aggaagggtc ttttagagtt
      361 taaacttcaa gaactagaac ttcattactc ttatttagtg aaaattaccg aagaaaaaga
      421 acaacaaaaa gcaataaaag aacagatgat agaagaggaa aaagttcgta gagaaattga
      481 tcgtgaaaag aaacgtattg ataaagaaca acgtcaattc aattctgaaa tttccaaatt
      541 aatcgcatat atgcaaaaag ctaatgcaga tgtggaaaaa gaattatatg caaataaaat
      601 tcaagaactg gaagaaaaat taaaagaatt agaagttata cgtgaaaatg tattacaaag
      661 agaattaaat actagagccg gttatgtgta tgtaattagt aatattgggt cttttggtga
      721 agacatatat aaaattggta tgactagaag attagaacct atggatagaa taaaagaatt
      781 gagtagtgca tcggttccat ttgaatttga cgttcatgcg atgatttttt cagaggacgc
      841 tccgtctttg gaaactaaat tgcataatca ttttagaaaa caagaagtta ataaaattaa
      901 tcaaagaaaa gaatttttca aagtttcact agacgaaata gagaaagttg ttttagaaaa
      961 ttataatgga acagtaacat ttacaaaatt agctaaagct gaacaatata gacgatcttt
     1021 agaattgtca aaagattaaa tatataaaaa gccttcgggc tttttctttt aacaattaat
     1081 aggaacgtat attcgaaagg aatagaaata atgtggttag aaaaaataaa tgacaaaaaa
     1141 tttaagtaca ccgaacgtta tacggatccc ttaactgaaa aaaagagaaa agtgtccgtt
     1201 actttatcta gcaattcacg ccaagcttgg aatcaagcta acttactttt gaatgaaaaa
     1261 atcgcagaaa aaataaaacg aaatgaagaa ttaccactaa cttttggaga attaaaaact
     1321 aaatgggatg aaaaatacaa gccaactgta aaagaaagtt cctatcgaac aactcaggtt
     1381 tatctatcat taatttcaaa atatataaaa gatgatgtac ttgtaaaaaa cgttaatagt
     1441 aatcttatac aagat
//
LOCUS       DAXQKX010000155         1424 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.169, whole genome shotgun sequence.
ACCESSION   DAXQKX010000155 DAXQKX010000000
VERSION     DAXQKX010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.169"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(150..1337)
                     /locus_tag="ACF3MF_002867"
     CDS             complement(150..1337)
                     /locus_tag="ACF3MF_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HFE3928753.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          414 a          309 c          249 g          452 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact ttta
//
LOCUS       DAXQKX010000156         1404 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.170, whole genome shotgun sequence.
ACCESSION   DAXQKX010000156 DAXQKX010000000
VERSION     DAXQKX010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1404
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.170"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            480..683
                     /locus_tag="ACF3MF_002868"
     CDS             480..683
                     /locus_tag="ACF3MF_002868"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928754.1"
                     /translation="MEQLMIRKVWPDVPALTPQQEAQILELYVRPAANFGRCGRAYQI
                     GINTLMQYFGYRIEKETESQNDD"
     gene            789..1226
                     /locus_tag="ACF3MF_002869"
     CDS             789..1226
                     /locus_tag="ACF3MF_002869"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928755.1"
                     /translation="MKRLVKSLVITATLLTGTIALAPQADAAWSGWQTEKFGHKARVY
                     TDAITYSSSASTVDWKAEKKGGSTLYYTAGVYKKRSGGGLTETGLLQRGSFKTSTPLK
                     SFSAKSIRSKTGKGTYVIQIDCYSDSGKRKYVGTFESAKFNVK"
BASE COUNT          416 a          328 c          364 g          296 t
ORIGIN      
        1 gcgttgtaca atccgattaa gacttccgag tctgtgaatt cgagagtcat cggaaataag
       61 gtatccggca ccctatcgct caacgaaacc gacacagaat atcaaaatat tccgatttaa
      121 cttgacattt tctatgcgct agcgcataat agagatatag aaaggaggga aaaacgattg
      181 aacgcggaaa cggtactaat cataacggcg atagtaaact tcgtcattgc ggtaacgaat
      241 ctggcaaccg cctgcgttaa cgcaaaaaac gctaatcgca aaaacgacta gcgccagaac
      301 attgatacgg ggttgattgg agagtccgcc ccgtgtctct tatagtaccg taaccataac
      361 gcaaacacaa ggaggcgagc gcgccatgtt aacggtatta accatcggca ttacagcggc
      421 ggccctgatc gtagcaatcg cgggtcttgt cgtagcacta aaacggaggc gataacggta
      481 tggaacagct tatgattcgt aaagtatggc cggatgtgcc agcattaaca ccgcagcagg
      541 aagcgcagat cctcgaatta tacgtgcgcc ccgccgccaa tttcggtcga tgcgggcgcg
      601 cttaccaaat cgggattaat acgctaatgc aatactttgg atatcgtatc gaaaaggaaa
      661 cggagagcca gaacgatgat tgaatacact tgccacgatt gcaattacgc aaagttagat
      721 atcgaaatca agccggacgc gtgctgccct acgtgtggta cgcggctgga agtcgaggag
      781 gaaatcgtat gaaacgttta gtcaaatcgc ttgtaatcac cgccacccta ttaaccggta
      841 ctattgcgtt ggctccgcaa gctgacgcgg catggtcggg ctggcagacg gagaagttcg
      901 ggcacaaggc gcgggtatat acggacgcaa tcacgtacag cagtagcgca agcacggtcg
      961 attggaaagc cgagaagaaa ggcggctcaa cgctgtacta cacggccggc gtttataaaa
     1021 agcgcagcgg cggtgggctg actgaaaccg gcttgttaca acgcggaagc ttcaagacat
     1081 caacgccgct gaagtcgttt agtgcgaagt ctatccgcag caagaccggc aaaggcacct
     1141 acgttattca gatcgactgc tattcggatt caggcaagcg caaatacgtc ggtacgtttg
     1201 agtcagcgaa attcaacgtt aaataatgaa cgaaatgagc cgcttcaagc tttcggatac
     1261 ctatcgtacc tgaacgcgtc tgaagcggct ctctcgttgt aatttcgtgg tataatcgtt
     1321 ctaaacaacg atgtaggaca cggaggtaca acgaaaatgg aggaaaaata cgagactaac
     1381 ggcattgata cgtcgatcac ttac
//
LOCUS       DAXQKX010000157         1391 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.171, whole genome shotgun sequence.
ACCESSION   DAXQKX010000157 DAXQKX010000000
VERSION     DAXQKX010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1391
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.171"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            131..292
                     /locus_tag="ACF3MF_002870"
     CDS             131..292
                     /locus_tag="ACF3MF_002870"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928756.1"
                     /translation="MARFILYTLIAVLLSIIINGSISLMNPEAGDTLSFPISILLGLI
                     AGWKAVLDD"
     gene            285..818
                     /locus_tag="ACF3MF_002871"
     CDS             285..818
                     /locus_tag="ACF3MF_002871"
                     /inference="COORDINATES: protein motif:HMM:NF014166.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HFE3928757.1"
                     /translation="MTSTKPIRILALDISTNPGFAVLEVKRLKSGTRVNLVHVTSVST
                     TSQSPDSHRYSYIEAAATMVLHEHGPFDVVVREHYTKGRNRRSTQTVFGAWAVIDLAL
                     GKYGHKADVEITPTTVKKDVTGKGSASKDEVEAGVRRILSLPADFTFRTDDESDAVAI
                     GLSYLVREKIIKPGEAE"
     gene            815..1180
                     /locus_tag="ACF3MF_002872"
     CDS             815..1180
                     /locus_tag="ACF3MF_002872"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928758.1"
                     /translation="MMERLIKWVTIAVIALFVFVFVVAAPAYTIASYHNENTYVIKVT
                     DKETKTSDDSSKYLIFGDDEKGNAKVFENTDALFARKFNSSDLYAEIEIGKTYEFKTI
                     GFRIPFMSNYENIMTVKEK"
     gene            1185..>1391
                     /locus_tag="ACF3MF_002873"
     CDS             1185..>1391
                     /locus_tag="ACF3MF_002873"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928759.1"
                     /translation="MFKRRVLETLSWMIIGAMFFLFGIFMRWALAFPVAKAIFTIAAV
                     FGLLLVGLYGIVRFILWLIVEPYRA"
BASE COUNT          355 a          310 c          385 g          341 t
ORIGIN      
        1 cggccgaact ggaagccctc cgcgataagg tttcgcgagt caaacggtcg aacgtctttg
       61 attctacgaa aaggcagtac gccggggcgc tagagtttat cgaaaaagta cgcaaagggg
      121 aggcggtctg atggcgcggt ttattcttta cacgttaatt gcggtattgc tttcgattat
      181 cattaacggt tcgatttcgc tgatgaatcc ggaagctggc gacacactat cgtttcctat
      241 ctctattctt ctagggctca tcgcagggtg gaaggcggta ttagatgact agcaccaagc
      301 ctatccgcat ccttgcgcta gatatatcga ctaatcccgg cttcgccgtc ctcgaagtca
      361 aacggctgaa gtcagggacg cgcgtgaatc tcgtacacgt aacgtctgtc agcacgacga
      421 gtcagtcgcc ggacagccac cgatattcct atatcgaggc agcggcaacg atggttctgc
      481 acgaacacgg accgttcgac gttgttgtcc gggagcatta cacgaaaggg cgcaataggc
      541 gatcgaccca aacggtgttt ggtgcgtggg ctgtcatcga cttagcgctt ggtaaatacg
      601 gacataaggc ggatgtggaa atcacgccga caacggttaa aaaggacgta accggaaaag
      661 gcagcgcatc aaaagacgaa gtcgaggcgg gagtgcggcg gatactttcg ctcccagccg
      721 actttacgtt tcggacagat gacgaatcgg atgcggttgc gattgggctt tcgtatcttg
      781 tccgcgagaa gattataaaa ccgggggagg cggaatgatg gagcgcttaa ttaaatgggt
      841 aactatcgcg gtaatcgcat tgttcgtatt tgttttcgtg gtagcggcgc cggcatatac
      901 gattgcgtct taccataacg aaaacactta cgtaataaag gtgacggata aagaaacaaa
      961 aacgtctgac gattcctcta agtatctgat tttcggagat gacgagaaag gtaacgcgaa
     1021 agtgttcgaa aataccgacg ctttgttcgc gcggaagttt aattccagcg atctgtacgc
     1081 ggagatcgaa atcggtaaga cgtacgaatt caagacgatc ggcttccgta ttccattcat
     1141 gtcgaactac gaaaacataa tgacggtaaa ggagaagtga tcggatgttt aagcggaggg
     1201 tactcgaaac gctttcgtgg atgattatag gcgcaatgtt ctttctgttc ggcatcttta
     1261 tgagatgggc gttagcgttt cccgtagcaa aagcgatatt tacgattgcg gccgtattcg
     1321 gactgcttct cgtcgggctt tacggaatcg tccggtttat cttatggctg atcgtcgaac
     1381 cctaccgcgc a
//
LOCUS       DAXQKX010000158         1374 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.172, whole genome shotgun sequence.
ACCESSION   DAXQKX010000158 DAXQKX010000000
VERSION     DAXQKX010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1374
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.172"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            33..1372
                     /locus_tag="ACF3MF_002874"
     CDS             join(33..474,474..1372)
                     /locus_tag="ACF3MF_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HFE3928760.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAENAYFKKVRNLDSRTRF
                     EQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYYWVKKLDKPDKYSKIKQEITAIVK
                     ESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMGLTCQIRIKRYKSYKGTVGKIAKN
                     VLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPILDLFNGEIISYSISTSPTYKLIEE
                     MLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLKENNIIQSMSRKGNCLDNSVIENF
                     FGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKRIKLKLNGLSPVEYRKQSIK"
BASE COUNT          576 a          177 c          239 g          382 t
ORIGIN      
        1 gactagaaat ctaattaaaa ggggtgcttt ttttgcggaa atatacattt gtttttaaga
       61 aaaaagtagt ttcagactat ttaaataacg aaggcggcta caaatatctt gcacataaat
      121 atcaaataaa tcgtacactg gttagacatt gggtaaggat ttataactat catggttggg
      181 aaggcttggt tggaggtggc aaaagctaca ctacaaaatt taaacttgat gttatagaat
      241 atatggaaac aaatggtctt tctatccaag aaactgctaa aaaatttaat atcggttcaa
      301 atagaactct aagtaaatgg atagagcaat atgaagaagg cggtgcttct tcacttgaga
      361 gccaaaaaag gggcagaaaa attagtatga attccaagct aaacattcct aaaaaactta
      421 aagatgagtc tcttgaagaa gaagttattc gtttaagagc agagaacgca tatttaaaaa
      481 agttagaaac cttgattcaa gaacaagatt tgagcaagaa gaaatcaagg ttaaaacaat
      541 ccttcagctc aaaaaagaat ttaaattgaa tctattactt tcaattgcac aattagcgaa
      601 gtcaacttat tattactggg taaaaaaatt agataagcca gataaatata gcaagataaa
      661 gcaagaaatt acagcgattg taaaagaatc aagaaactct tatggttatc gtagagtcac
      721 tttagcgtta aagatgaaag gatatacaat caatcataaa acagttagaa aattaatgtc
      781 ccaaatggga cttacctgtc aaatccgaat aaagcgatat aaatcttata aaggaacagt
      841 aggaaaaatt gccaagaatg tgttaaaacg aaatttttca gtagatacac ccaataaaaa
      901 atgggtgaca gacgtcactg aattcaagat aaaaggaaga aaaatctatc tatctcctat
      961 acttgattta tttaacggag aaataattag ttatagtata tcaactagtc caacatataa
     1021 actgattgaa gaaatgcttc aacaagcaat taaaaaaaag ggaactgagg gttcactgat
     1081 tctacattca gatcaaggat ggcagtatca gatgccacaa tatcaaaaaa aattaaaaga
     1141 gaataacatt attcaaagca tgtctagaaa aggaaattgc ttagataatt ctgtaataga
     1201 aaattttttt ggtgtgctta aatcagagtt tttttatcga gaaaaattcc gatcaattga
     1261 gatatttcaa agtaaattaa atgagtatat taggtggtat aataacaaaa ggataaaact
     1321 aaagttaaat ggactatctc cagtagaata tcggaaacag tccattaaat agtt
//
LOCUS       DAXQKX010000159         1359 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.173, whole genome shotgun sequence.
ACCESSION   DAXQKX010000159 DAXQKX010000000
VERSION     DAXQKX010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1359
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.173"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            313..855
                     /locus_tag="ACF3MF_002875"
     CDS             313..855
                     /locus_tag="ACF3MF_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928761.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            1011..>1359
                     /locus_tag="ACF3MF_002876"
     CDS             1011..>1359
                     /locus_tag="ACF3MF_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="HFE3928762.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMP"
BASE COUNT          525 a          166 c          260 g          408 t
ORIGIN      
        1 ctgcgcaagg cttaccagcg agatagagat cgacgatttg ttgtttgaat tcttttgaat
       61 aggttcttcg ttgacgtctt ggcatgaaaa atcctccagt gtgtttttta ttattctaca
      121 caccttattt tttctgtcta gtctagtgta gccgattcaa gttcttcgtg ttctcttaga
      181 cataaaaatt cctcctggta tgttttcttc tagtctacac accttaattt ttctgtctag
      241 ttaattgtag cctatccagt ttggaaaaat aaaaaattat atttcatcaa cgtttcataa
      301 aaggtgtgta gaatgttatt gaaagtagct ataaaatgct attgtgtaaa aaataaagga
      361 ggaataattt atgaaaaaat agtaccaaga ggagcatgcc tattacttgc attatgtttg
      421 agcttaagcg cagttgggtg tcaaaaaagt aatgaaaaca ataaaataaa agaaggacaa
      481 tccataagtt ctgaagagga aggcatgtca attaatgcaa atggcaaaaa tgaaactttt
      541 aagccatcag attatacatt ggaggcaaag aaagaatatg tttatgaata tttagggctt
      601 aaatttaaac tctcagacaa atttagaaat tatatagctg ataaaaagat agcgatgtta
      661 gatgatcaaa gtcctataga taaagaacta aagtatgcta ttttgacatt tgagaaaatg
      721 acagaagaac aaaagaatgc agttatagaa aagatgggcg atggatataa aaattggcaa
      781 aatgagcttg aaagaattgg gactattggt atatttgaaa aaaatacatc agaagaaaaa
      841 aatctaaaat tataaaatgt gatactcata ctaaaatagg agtttcaagt gatggaaaat
      901 acgattgcta tttaagcaca aatagcggag ctgaaagtaa tcttcttgat gaattaaaaa
      961 gaactgagat tcaaattata gataaaaaag aacgtcctaa aaatggtttt gtgctatcag
     1021 aaaaaactga tttagaaaat acagaagcat ttaacaaaga atcggttaaa gatttacgta
     1081 aactaccaac aaaggacata aatggcaagg attttacaag taaagatttt gagaagtatg
     1141 atcttactat ggtaaatgta tttgcaactt ggtgtacagc ttgtgtaaag gaaattcctg
     1201 atttggttga ggttcagaat gaaatgaaaa gcaagggtgt aaatatcgtt ggagttgtta
     1261 cagatcctgt tgatgataac ggtgaaaaca aggaagcaat tgaaaagtca aagttaatac
     1321 atgaaaagac aaaggcttca tatcctttct taatgccag
//
LOCUS       DAXQKX010000160         1351 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.174, whole genome shotgun sequence.
ACCESSION   DAXQKX010000160 DAXQKX010000000
VERSION     DAXQKX010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1351
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.174"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            25..1326
                     /locus_tag="ACF3MF_002877"
     CDS             25..1326
                     /locus_tag="ACF3MF_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFE3928763.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT          441 a          270 c          251 g          389 t
ORIGIN      
        1 aacacaatca aaggagcgtt ctgtatgcct gatcttcatc atatcaaact actacttgga
       61 atcaaagata aaaacatttt catcacaaat gtggaatcga agagcattaa gaatatcaag
      121 agtcttgttg tttctgcgac gttaagtaaa gaaattcgtc gctgtccttt gtgtaaacag
      181 atgaatcatg aaggcatgat cgttaagaac ggaaagaaaa aatcgctcat tcaacttaat
      241 aaatgtgcga accaactgac ttatcttgct ttagcgaaac aacgctacca ctgtcgtggc
      301 tgccacacct attttacggc gaatacctac attgtcgata gaaactgctt tatcgctaaa
      361 caagtgcgct ataaaatttt agaagagcta actgaaaaac aagcaatgac gacaattgct
      421 aagcattgcg gcgtttcttg gtcgaccgtt tctcggacac tcgcttctct gatccccatg
      481 acaaaagtaa aaagaaattg gttaccgcgt tgtttattaa tggatgaatt tcgttcactg
      541 aaaaatcaag tcggtcccta ctccttttct tgtatggatg gcgatactgg aaaattactg
      601 gatattcttc cttcacggaa gaaaaaggct ctcgtttctt attttatgca atttgaacga
      661 cgcgcacgat tgaaggtaaa ggtcatcgtg acggacatga atgtttctta tgcctctctg
      721 ataaaggaat gttttccaaa ggcaaaactc gttgtggatc gttttcacat tgtcaaacat
      781 ctcattcgta aatttgagga tattcgcgta cgaatcatga aaagctttga tcgaaacgat
      841 ccaacacaag ccaaatatta tcgacaatta aaggcgttgt ctcggcttct gatcaaacga
      901 caggacaagc ttgtttatga caaatggacc aaatggcgca attttggttg ggcgtatctc
      961 accgaaagtg aagtggtgga tcgtctgctt tcgatctctg acgaattacg aatcgcctat
     1021 ttttactatc aagaaattct tcaagcgttt cacgacaaag aggcggacac tttctttaaa
     1081 cttgtaagaa cgatgcccaa ttccgttcca aaagaactgc attctataaa aaaagctttt
     1141 ataaactatg aatccggcat tcgtttagcc ctcgaattgc cttattcaaa tgccaaaata
     1201 gaaaatctgc atacccacat caaagcattg aaacgagtcg cttatggctt tcgaagcttt
     1261 cggaaaatga agaccagaat tttcttacta aataatctga ttacctatga atcaaaaaac
     1321 atctaaagta gaaaaggaat tctaccttag a
//
LOCUS       DAXQKX010000161         1328 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.175, whole genome shotgun sequence.
ACCESSION   DAXQKX010000161 DAXQKX010000000
VERSION     DAXQKX010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1328
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.175"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..172
                     /locus_tag="ACF3MF_002878"
     CDS             <1..172
                     /locus_tag="ACF3MF_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HFE3928764.1"
                     /translation="RPIKRRNKFYQSLRTASSTIKGMETIRGIYKKNRRNGTLFGFSV
                     STEIKVLMGITA"
     gene            221..589
                     /locus_tag="ACF3MF_002879"
                     /pseudo
     CDS             221..589
                     /locus_tag="ACF3MF_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631768.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(626..1183)
                     /locus_tag="ACF3MF_002880"
     CDS             complement(626..1183)
                     /locus_tag="ACF3MF_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928765.1"
                     /translation="MEIGYIASEKDRIIDYLADKDYDLKLLSVHHNGQFDYLDDEVKD
                     MDPAIVIPQYFAQLSEALVVIEADVFAHFDYGFRVFGLSVAEFKQYEAQFLPILDQVI
                     KNKLAFELNAKSAYLYDNLALYEYVIDLYLSRGGTLFSVGSDGHYLEHFRFHFDDLFA
                     LLKAKGVTELAIYQKGKRIMVPLPV"
BASE COUNT          477 a          241 c          232 g          378 t
ORIGIN      
        1 tcgacctatt aaacgacgaa ataaatttta tcaaagtctc cgtacagcct cttccacgat
       61 taagggcatg gagaccattc gaggaatata taaaaagaac cgaagaaatg gaacgctctt
      121 cggcttttcg gtgtctactg aaatcaaggt attaatggga ataacagcct aagatatttg
      181 gagttcagag agggcgcgtt tgattttcaa acttcgcaac agaacccaat tgacaactga
      241 aatattggca gtagaattgg cacagtcaac cagtaaattt attggtatta aggatcatca
      301 aatactcatt ggttatatga aagtcaataa tgaaaaagat gctatagaga ttcaacggct
      361 ctatctgctc aaagattatc aaaacaaagg gttagggcaa cggttactcg atgaagcgaa
      421 tcgttatgct aaaacgaaac aaaaacgtta tttacgtttg actgtttatg aaaaaaatca
      481 tgcaggtatt cgtttttatg aacgtcatgg atttaaaaaa atcgggatca aacatttccc
      541 tttaggaaaa caagatcgta tttgtccgat tttagaaaaa gaaatctaaa aaaacgtcct
      601 cacttttgat gctgaggacg tttttttaga ctggtaatgg aaccataatt cgctttcctt
      661 tttgataaat cgctaattcc gtcacacctt ttgcttttaa cagagcaaaa agatcatcga
      721 aatggaaacg gaaatgttca aggtaatgcc catctgatcc aacactaaac aaggtaccac
      781 cacgtgaaag atataaatcg atgacatatt catataacgc taaattgtca tacaagtaag
      841 cgctcttagc atttaattcg aatgccaatt tatttttgat tacttgatct agaatcggta
      901 aaaactgcgc ttcatattgt ttaaattcag caacggatag accaaatacc cgaaaaccat
      961 agtcaaaatg agcaaagaca tctgcttcta taacaactag tgcttctgaa agttgtgcaa
     1021 aatactgagg aatcacaata gcaggatcca tatctttgac ttcgtcatct aaataatcaa
     1081 attgaccatt atgatgcaca ctgagtaatt ttaaatcgta atctttatcg gctaaatagt
     1141 cgatgatccg atccttttca gaagcgatgt aaccgatttc gatgcctcgc cgtttgtata
     1201 attaagcgag acaaataaaa aagccattta tgttacactc aaattgtaat acccgctaaa
     1261 gcatacaagg agagtgaaca taaatgactt atacccatct tacaccaaac gagcttgtaa
     1321 tgatagaa
//
LOCUS       DAXQKX010000162         1206 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.178, whole genome shotgun sequence.
ACCESSION   DAXQKX010000162 DAXQKX010000000
VERSION     DAXQKX010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1206
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.178"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..742)
                     /locus_tag="ACF3MF_002881"
     CDS             complement(<1..742)
                     /locus_tag="ACF3MF_002881"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928766.1"
                     /translation="MEVRIDGRNFDDLCIKTRKGDEGMTKIHVLADETLGGIKREYVE
                     VDRKAEVGEKIVIVEKDDLEEGYENGDVFTVDRHRPGKSHVESDEARCGGNIDGFILR
                     EEYHVLEPTDIVHIDGERYVLTDRKAEVGEKIIHLYEGESSGIAREVRKTDDEGVEVD
                     PYEDEEGVWIGLYHGYYRVLVPVEAAEDEPKPADPIDVIASLAQEVAFLKRTVDRHRD
                     EIDTLYKDKRTLGEELERLKEPTKTAECA"
     gene            complement(758..>1206)
                     /locus_tag="ACF3MF_002882"
     CDS             complement(758..>1206)
                     /locus_tag="ACF3MF_002882"
                     /inference="COORDINATES: protein motif:HMM:NF018437.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="3D domain-containing protein"
                     /protein_id="HFE3928767.1"
                     /translation="KAAELAAKDAKIKALESELASVKDEVKAQANEKREKPPHKHAQT
                     SGWQTFEATAYTAYCAEGCTGTTATGLDVSHTIYHAGKRIIAVDPSLIALGSTVEVRQ
                     ADGTTFEAVAQDTGSTIKGAKIDVLVTDEADAVQFGRQSVQVRVIN"
BASE COUNT          219 a          382 c          262 g          343 t
ORIGIN      
        1 gagcgcactc tgcagtcttc gtcggctcct tcaaccgctc caactcttcg ccaagcgtcc
       61 gtttgtcttt atacagcgtg tcgatttcgt ctctatggcg atcaaccgtt cgttttaaaa
      121 acgctacctc ttgcgctaaa ctggcgataa cgtcgattgg gtcggctggc ttcggttcgt
      181 cttcggcggc ttcgaccggg acgaggacgc gataatatcc gtgatataaa ccgatccaca
      241 ccccttcttc gtcttcatac ggatcgacct ctactccttc gtcatcagtc ttacgaacct
      301 ctctcgcgat tccactcgat tcgccttcgt ataggtgaat aatcttctcg cccacttccg
      361 ccttgcgatc ggttaaaacg tagcgctcgc cgtcaatatg aacgatgtcg gtcggttcga
      421 gtacgtgata ttcttcgcga aggataaatc cgtcaatgtt gccaccgcat ctagcttcgt
      481 cactttctac gtgcgacttt cccgggcggt gtcgatcaac tgtaaaaaca tcgccgttct
      541 cgtacccttc ctcgagatca tccttctcca caattacgat cttctcgcca acctccgcct
      601 tccgatcgac ctctacgtat tcgcgcttga taccgccaag tgtttcgtca gccagtacgt
      661 ggattttcgt cataccttcg tcccctttcc tcgttttgat gcacagatca tcgaaatttc
      721 ttccgtctat tctgacttcc atccgatcgt cctcccgtta atttattacg cgaacctgca
      781 ccgactgccg cccgaactgt accgcgtcgg cttcgtccgt aactaacacg tcaatcttgg
      841 cgcccttaat cgtgctccca gtatcctgcg ccacggcttc aaacgtcgtg ccgtctgcct
      901 gccgcacctc aaccgtcgag cctaacgcaa tcaatgacgg atcgaccgct ataatacgct
      961 tgccggcgtg gtagatcgta tggctgacgt cgagaccggt cgctgtggtt ccggtacacc
     1021 cttccgcgca ataagccgta tacgcggttg cctcgaacgt ttgccagccg gatgtttgtg
     1081 cgtgcttatg cggcggcttc tcgcgctttt cgttagcctg cgccttaact tcgtctttta
     1141 cggaagcaag ttcggattca agcgctttta tcttcgcatc cttggccgcc agttcagcgg
     1201 cctttc
//
LOCUS       DAXQKX010000163         1193 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.179, whole genome shotgun sequence.
ACCESSION   DAXQKX010000163 DAXQKX010000000
VERSION     DAXQKX010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1193
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.179"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..1076
                     /locus_tag="ACF3MF_002883"
     CDS             <1..1076
                     /locus_tag="ACF3MF_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFE3928768.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          210 g          331 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tct
//
LOCUS       DAXQKX010000164         1175 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.180, whole genome shotgun sequence.
ACCESSION   DAXQKX010000164 DAXQKX010000000
VERSION     DAXQKX010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1175)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1175)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1175
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.180"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..>1175
                     /locus_tag="ACF3MF_002884"
     rRNA            <1..>1175
                     /locus_tag="ACF3MF_002884"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          351 a          235 c          348 g          241 t
ORIGIN      
        1 ctgaaacatc taagtacctg caggaagaga aagaaaattc gattccctga gtagcggcga
       61 gcgaaacggg aaaagcccaa accagcaagc ttgcttgttg gggttgtagg actccaatat
      121 ggtagttctt tcagatagtc gaatgacttg gaaaagtcag tcaaagaggg taaaaacccc
      181 gtagacgaaa tgtggaagac acctaggagg atcctgagta cggcggaaca cgagaaattc
      241 cgtcggaatc cgggaggacc atctcccaag gctaaatact ccctagtgac cgatagtgaa
      301 ccagtaccgt gagggaaagg tgaaaagcac cccggaaggg gagtgaaata gaacctgaaa
      361 ccgtgtgcct acaacaagtc aaagcccgtt aatgggtgat ggcgtgcctt ttgtagaatg
      421 aaccggcgag ttacgattgc atgcgaggtt aagttgaaga gacggagccg cagcgaaagc
      481 gagtctgaat agggcgtttg agtatgtagt cgtagacccg aaaccatgtg atctacccat
      541 gtccaggttg aaggtgcggt aaaacgcact ggaggaccga acccacgtac gttgaaaagt
      601 gcggggatga ggtgtgggta gcggagaaat tccaaacgaa cttggagata gctggttctc
      661 tccgaaatag ctttagggct agcctcggaa ttgagaatga tggaggtaga gcactgtttg
      721 gactaggggc ccatctcggg ttaccgaatt cagataaact ccgaatgcca ttcattcata
      781 tccgggagtc agactgtgag tgataagatc catagtcgaa agggaaacag cccagaccac
      841 cagctaaggt cccaaaatat atgttaagtg gaaaaggatg tggggttgca cagacaacta
      901 ggatgttggc ttagaagcag ccaccattta aagagtgcgt aatagctcac tagtcgagtg
      961 accctgcgcc gaaaatgtac cggggctaaa catattaccg aagctgtgga gtacaccttt
     1021 aggtgtattg gtaggagagc gttctaaggg cgttgaaggc agatcgtgag gactgctgga
     1081 gcgcttagaa gtgagaatgc cggtatgagt agcgaaagac aggtgagaat cctgtccacc
     1141 gaatgactaa ggtttcctgg ggaaggctcg tccgc
//
LOCUS       DAXQKX010000165         1136 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.181, whole genome shotgun sequence.
ACCESSION   DAXQKX010000165 DAXQKX010000000
VERSION     DAXQKX010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1136
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.181"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            96..506
                     /locus_tag="ACF3MF_002885"
     CDS             96..506
                     /locus_tag="ACF3MF_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFE3928769.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     TLAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            520..876
                     /locus_tag="ACF3MF_002886"
     CDS             520..876
                     /locus_tag="ACF3MF_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFE3928770.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVEKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT          397 a          165 c          210 g          364 t
ORIGIN      
        1 ttattttgat ttttttttat attttattag ctaataattg gtattttaaa agaaattact
       61 gtagaattgg attataatta aaaaggagtg agaaaatgat aaaagtatat acttcgccta
      121 gctgtacttc ctgtagaaaa gcaagagcat ggttgcaagc gaatcaactt gaatttgaag
      181 agaagaatat ttttgccgaa ccgttaacag aaagtgagat caaaaagacc ttggcagcga
      241 ctgaaggagg agttcaagat attatttcca ctcggtcgaa aatttacgaa aagctgggca
      301 tagattttaa cgaattaact ttaaagcaaa tgatcgtctt attcaaagaa tatccttcat
      361 tattgagacg acctattttg attgatgaaa aaagaatact aatcggattt aatgaagatg
      421 agatccggtc atttgtccct cgtgaaattc gatgtgttgc cagaaatctg atctatttac
      481 aaaacaataa catcttaaat tcatagggag ggagccttcg tggaagtgaa agtctatgga
      541 tcagcgcact gtgtaacaag tctgaaggcg aaacaatggt tagaacacca tcaattgcct
      601 tatcaatttg ttgacttaga agaacgcgat ctaagtacag aagaagcaga agaattatgc
      661 agttttgaag aagtgcaagc agaacagcta tttgcgactt ggtctgaggc ttttcacaac
      721 attgcgattg acctttcctg tgtagaaaaa aaacaactga tttttttatg cacacaacat
      781 accaacctcc tcagacgtcc tttgattatt atcgatgaag ttctatttat tggatacaat
      841 gagcagttga tggaacagct tatcttaaat aaatagactt taactgtttt aatcaagtca
      901 ctgagcattc catacagttg taacagtcga acacttagca tcaagcgtgt tatgtgttct
      961 ttttttgact ttatttttct actatagaga catgctcaat ttatgtggtc aaaattcaaa
     1021 tctaggtggg gatatagagt taaaaatata ttgacatgtg taaatttaca tgatatattc
     1081 atttctgttg ttttaagtag caaagcaata aaatagtatt ttaaaaaaca tataaa
//
LOCUS       DAXQKX010000166         1073 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.182, whole genome shotgun sequence.
ACCESSION   DAXQKX010000166 DAXQKX010000000
VERSION     DAXQKX010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1073
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.182"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(47..286)
                     /locus_tag="ACF3MF_002887"
     CDS             complement(47..286)
                     /locus_tag="ACF3MF_002887"
                     /inference="COORDINATES: protein motif:HMM:TIGR01560.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail connector protein"
                     /protein_id="HFE3928771.1"
                     /translation="MALTLDEAKEYLRVDGDEEDKLVSFFISAAEKHMENAGVKDTES
                     DLYKMAALIFVADAYENRTTANSGTKIAGMILQLR"
     gene            complement(289..777)
                     /locus_tag="ACF3MF_002888"
     CDS             complement(289..777)
                     /locus_tag="ACF3MF_002888"
                     /inference="COORDINATES: protein motif:HMM:NF014427.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig domain-containing protein"
                     /protein_id="HFE3928772.1"
                     /translation="MSLNWDAVTFNGGIKEYEVYRDGVSIGSRVGTSFSDSGLTQLTT
                     YKYQVRAIPNTGDPSPLSAELSVTTLATEPTGVNVTETSKTLTVGDTYKINATVTPSS
                     ADQSVTFTSSSTATATVSSSGLVTAKAAGTTTITVASKSKPSVKKTVAITVNEPAPPA
                     GE"
     gene            complement(818..>1073)
                     /locus_tag="ACF3MF_002889"
     CDS             complement(818..>1073)
                     /locus_tag="ACF3MF_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFE3928773.1"
                     /translation="NGNATLYSAQPEQILGKPVVFSDAAVSPIVGDFRYSHFNYDPAI
                     TYESDKDVKTGENVFVLTAYFDHKIKLKSAFRIAKVETTP"
BASE COUNT          230 a          263 c          270 g          310 t
ORIGIN      
        1 aacgtgatcc tcttattaaa acttccgatg tttaccgcca tagcgctcac ctcaattgaa
       61 ggatcatacc ggcgattttt gttccgctgt tagctgtcgt cctgttttcg taggcgtccg
      121 caacaaagat cagtgccgcc attttgtaca ggtccgattc ggtatccttt acgcctgcgt
      181 tttccatgtg cttttctgct gcggaaataa aaaaggagac gagtttatcc tcctcatctc
      241 catcaacccg caagtattct tttgcttcat caagcgtaag tgccatcgtt attcacctgc
      301 cggaggtgcc ggttcgttga ccgtaatagc caccgttttc ttaaccgaag gtttcgactt
      361 agacgcgaca gtgatcgtgg ttgtgccggc cgctttagcc gttactaagc cggagctaga
      421 tacggttgct gtcgcggtac tgctagacgt aaaagtcacg ctttggtctg cgcttgaagg
      481 cgtgaccgtt gcgttaatct tatacgtatc gcccaccgtt aaggtcttgg aggtttccgt
      541 tacgttgacg cctgtaggtt cggtcgctaa cgtagtcacc gaaagctcgg cactaagtgg
      601 cgacgggtca ccggtgttag gaattgcgcg cacctgatac ttatacgttg ttaattgcgt
      661 caagccgctg tctgaaaacg atgtccctac gcgagatccg atagatactc cgtctctgta
      721 cacctcgtat tctttaatgc ccccattgaa ggttacggcg tcccaattga gggacaccga
      781 tgtgtcttta ggagtcgccg ttaacccttg gggcgcatta gggcgtagtt tcgactttcg
      841 cgatacggaa tgcagattta agtttgattt tgtgatcaaa atacgcagtc aatacgaata
      901 cgttttcgcc agttttaacg tctttatcgc tttcgtaagt gatcgctgga tcgtagttga
      961 agtgagagta acggaagtca ccaacgatcg ggctaactgc ggcatcagag aagacgaccg
     1021 gcttgccgag aatttgctca ggttgcgcgc tgtacagtgt ggcgttaccg ttc
//
LOCUS       DAXQKX010000167         1061 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.183, whole genome shotgun sequence.
ACCESSION   DAXQKX010000167 DAXQKX010000000
VERSION     DAXQKX010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1061
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.183"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..829
                     /locus_tag="ACF3MF_002890"
     CDS             <1..829
                     /locus_tag="ACF3MF_002890"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928774.1"
                     /translation="KNVGGKRMTQFQTGAEAIGSLIGGNGGGSNKEKVEFTRLGEEPI
                     KVRVKGPFDLMRYFAYGVHKQVNTFIAKNPPTYNKDGFASGNLTPWDKASDYYYKLAQ
                     KEPDKSAKRLELSALGYRFRAKPRYIMGFYDLESGKDIIVDFTKNQAMAVYSTIREYV
                     ELDKQGNVIDGGEHEIYDMAFKLSKKGSGTNTTGSLAPIINLSKGLTAEEQANLEASA
                     GQPFDTTMFDGVLYEMDEEEMTKSLVKADFDISILGLTIGGSAAESNEAPAEDSFGF"
     gene            869..>1061
                     /locus_tag="ACF3MF_002891"
     CDS             869..>1061
                     /locus_tag="ACF3MF_002891"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928775.1"
                     /translation="MAHKAEDTGKYSELIARAALLASGWQAVSTSETEEAFDISAKDP
                     LSGEWKTFQVKTIYDRKKRG"
BASE COUNT          329 a          221 c          277 g          234 t
ORIGIN      
        1 taaaaacgta gggggaaaac gaatgacaca atttcagaca ggcgcagagg caatcggttc
       61 attaatcgga ggtaatggtg gcggttcgaa taaagaaaag gtcgaattta cacgccttgg
      121 tgaagagccg attaaggttc gcgtcaaagg tccattcgat ttaatgcgtt actttgctta
      181 cggagtacac aaacaggtca atacgtttat tgcgaagaat cctccgactt acaacaagga
      241 cggatttgca agcggaaacc taaccccgtg ggataaagct tccgattact attataaatt
      301 agcacagaaa gagccggata aatcagcgaa acggcttgag ctttctgcgc tcggctatag
      361 attccgtgcg aaaccgcgct atattatggg attctacgac ctagagtccg gaaaagatat
      421 tatcgtcgac tttacgaaga accaagcaat ggcagtgtac tcaaccattc gcgagtatgt
      481 cgagcttgat aagcaaggca acgtcattga tggcggtgag catgaaattt acgatatggc
      541 gtttaagctt tcgaagaaag gaagcggcac taacacgact ggatcactcg cgccaatcat
      601 taacctctcg aaaggtttga cggcagaaga acaagcgaat cttgaagctt ccgcgggcca
      661 gccattcgat acaactatgt ttgacggtgt attgtacgaa atggacgaag aagaaatgac
      721 taagtcgctc gtcaaagcag actttgatat cagcattctc ggattaacaa tcggtggcag
      781 cgcggcagaa tctaacgaag ctcctgccga agattcattc ggattttaat cgcgatcaga
      841 cataaccaaa cgaaaaggag gcgcttatat ggcgcataaa gcagaagata ccggcaagta
      901 ttcggaactg atcgcgcgtg ctgcgctgct ggctagcggc tggcaggcgg tcagtacgtc
      961 cgaaacggaa gaggcattcg atattagcgc aaaagatccg ttaagtggcg aatggaaaac
     1021 gtttcaggtg aagacgattt acgatcggaa gaagcgcggc a
//
LOCUS       DAXQKX010000168         1058 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.184, whole genome shotgun sequence.
ACCESSION   DAXQKX010000168 DAXQKX010000000
VERSION     DAXQKX010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1058
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.184"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(36..992)
                     /locus_tag="ACF3MF_002892"
     CDS             complement(36..992)
                     /locus_tag="ACF3MF_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928776.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          344 a          176 c          160 g          378 t
ORIGIN      
        1 tagaaaaagc agtcggactt tctaaaagaa gttcactatt cgatcctgtc gatgatttct
       61 tcaggaaaat cgtctatttg cttgtcaatt ttgctgtctt tgtatttctc ttcttggata
      121 gtcaacaaaa tctttgtaag attcccccag tctactgctc ttggcggatc gagccaaacc
      181 actacttgag atgcactttc ttcatataga ttattcctat tcgtgattat aacatccggg
      241 aactcaggct ttcctgcctc tatcacttcc gtgttcagat taatgtacaa gcttaaattt
      301 ttcttgataa attgattata ggcagcacca taagaaaaat cgatgatgat ctttactggt
      361 tcagaaatca gttgaatggg tatgtgattg atcaataata ataaataact gaaaaaaaga
      421 aaaaatttat cttgaagcaa ctctttgcgt tttgacgtta gatcatttat atactctatc
      481 aaatagcaat aaaatgctgg atagttttct ctaaaaaaag aaacatcaag tggaaattca
      541 tcagctttat taatagtgta atgcaaaagt ttaaaatgta ttttggttaa ctctcttcgg
      601 atcaattggc tcgtctcttc tcgcaacaga ttaaactgat tttcaaaact ttcaatgaat
      661 cgttcattca accattcgat tgtttcatct tcattttttc tcaagtattt ttgatccaat
      721 ttatcatgaa gataaagcca agagagtgtc ttattgataa aaataacgga tttttctcct
      781 aatactcctt ttaagtggta aaatcctata tccgaaaaaa atagcgactg attgctagca
      841 atatctaaag aatcagcttg ttcagccaac aggttgattg ctaaaaagtg gaataatttc
      901 tttttttcat aagcagacag aggataatac tgttttaaat cttttaacat tttttctgtt
      961 tttataatta taggtagcgt atacaattcc acaaaactta tctctgttga gttaaaaaga
     1021 ttatataaaa aaagccgaat gtttttagga ttccctgt
//
LOCUS       DAXQKX010000169         1050 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.185, whole genome shotgun sequence.
ACCESSION   DAXQKX010000169 DAXQKX010000000
VERSION     DAXQKX010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1050
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.185"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..>1050
                     /locus_tag="ACF3MF_002893"
     rRNA            <1..>1050
                     /locus_tag="ACF3MF_002893"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          281 a          233 c          333 g          203 t
ORIGIN      
        1 ccatttaaag agtgcgtaat agctcactgg tcgagtgact ctgcgccgaa aatgtaccgg
       61 ggctaaacgt atcaccgaag ctgcggactg ttcttcgaac agtggtagga gagcgttcta
      121 agggctgtga agcaagaccg gaaggacttg tggagcgctt agaagtgaga atgccggtat
      181 gagtagcgaa agaggggtga gaatcccctc caccgaatgc ctaaggtttc ctgaggaagg
      241 ctcgtccgct cagggttagt cgggacctaa gccgaggccg aaaggcgtag gcgatggata
      301 acaggttgat attcctgtac cacctcctca ccatttgagc aatgggggga cgcaggagga
      361 tagggtaagc gcggtattgg atatccgcgt ccaagcagtt aggctgggaa ataggcaaat
      421 ccgtttcccg tgaaggctga gctgtgatgg cgagcgaatt atagtagcga agttcctgat
      481 tccacactgc caagaaaagc ctctagcgag gtgagaggtg cccgtaccgc aaaccgacac
      541 aggtaggcga ggagagaatc ctaaggtgat cgagagaact ctcgttaagg aactcggcaa
      601 aatgaccccg taacttcggg agaaggggtg ctctgttagg gtgcaagccc gagagagccg
      661 cagtgaatag gcccaggcga ctgtttagca aaaacacagg tctctgcgaa gccgtaaggc
      721 gaagtatagg ggctgacgcc tgcccggtgc tggaaggtta agaggagcgc ttagcgtaag
      781 cgaaggtgcg aattgaagcc ccagtaaacg gcggccgtaa ctataacggt cctaaggtag
      841 cgaaattcct tgtcgggtaa gttccgaccc gcacgaaagg cgcaacgatc tgggcactgt
      901 ctcaacgaga gactcggtga aattatagta cctgtgaaga tgcaggttac ccgcgacagg
      961 acggaaagac cccgtggagc tttactgcag cctgatattg aatgttggta cagcttgtac
     1021 aggataggta ggagccttgg aaaccggagc
//
LOCUS       DAXQKX010000170         1034 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.186, whole genome shotgun sequence.
ACCESSION   DAXQKX010000170 DAXQKX010000000
VERSION     DAXQKX010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1034)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1034)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1034
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.186"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            118..1014
                     /locus_tag="ACF3MF_002894"
     CDS             118..1014
                     /locus_tag="ACF3MF_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFE3928777.1"
                     /translation="MIQYYYIKKEWGVVMEKEELKILEELRRILNSKNEAIVILNNYF
                     KGGVGKSKLSTMFAYLTDKFNLKVLMIDKDLQATLTKDLAKTFKVELPRVNFYEGLKN
                     GNLASSIIHLTDNLDLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIII
                     DTVPTPSVYTNNAIVASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFV
                     PYLVDTDSATIKSNLEELYKEHKEDNLVFRNIIKRSNKVSTWSKNGITEHKGYDKKVL
                     SMYENVFFEMLERIIQLENEKE"
BASE COUNT          396 a          151 c          170 g          317 t
ORIGIN      
        1 tctttttcaa aataaacata aaagcccttt aaagagggct tttatatatt aatcacaaat
       61 cacttatcac aaatcacaag tgattaatca caaatcactt gtgatttgtg attcctaatg
      121 atacaatatt actatataaa aaaagaatgg ggcgtagtta tggagaagga agaactaaaa
      181 atacttgaag aattaagacg tattttaaac agtaaaaatg aagcaattgt tatcttaaac
      241 aattatttta aaggtggtgt tggaaagtca aaattatcga ctatgtttgc ttatttgaca
      301 gacaaattta atttaaaagt tttaatgatc gataaggact tacaagcaac attgacaaaa
      361 gacttagcaa aaacatttaa ggtagaattg ccacgtgtca atttttatga aggcttgaaa
      421 aatggaaact tggcttcttc tattattcat ttgactgata atttagactt gatccctggc
      481 acgtttgatt tgatgttact gccaaaatta actcgctcat ggacgtttga aaacgaaagt
      541 agattgcttg ctactctttt agcaccttta aaaagtgact atgatctcat tattattgat
      601 actgtaccaa cgccaagcgt ttatacaaat aatgcaatcg tggcaagtga ttacgttatg
      661 atccctttac aagcagaaga agaaagtaca aacaacattc aaaactatat ttcctatttg
      721 attgatttac aagaacagtt taaccctgga ctagatatga tcggttttgt tccttattta
      781 gttgatacgg acagcgcaac gataaaatca aacctggaag aactgtacaa agaacataaa
      841 gaggataatt tggttttccg aaatattatc aagcgaagta ataaagtaag tacctggtct
      901 aaaaacggca ttacagaaca caaaggctat gacaaaaaag ttttatctat gtatgagaac
      961 gtattttttg aaatgcttga gcgaatcatt caattagaaa acgaaaaaga atagaatcac
     1021 aaatcacaag tgat
//
LOCUS       DAXQKX010000171         1008 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.187, whole genome shotgun sequence.
ACCESSION   DAXQKX010000171 DAXQKX010000000
VERSION     DAXQKX010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1008)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1008
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.187"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            85..981
                     /locus_tag="ACF3MF_002895"
     CDS             85..981
                     /locus_tag="ACF3MF_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFE3928778.1"
                     /translation="MIQYYYTKKEWGVVMEKEELKILEELRRILNSKNEAIVILNNYF
                     KGGVGKSKLSTMFAYLTDKFNLKVLMIDKDLQATLTKDLAKTFKVELPRVNFYEGLKN
                     GNLASSIVHLTDNLDLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIII
                     DTVPTPSVYTNNAIVASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFV
                     PYLVDTDSATIKSNLEELYKQHKEDNLVFQNIIKRSNKVSTWSKNGITEHKGYDKKVL
                     SMYENVFFEMLERIIQLENEKE"
BASE COUNT          385 a          149 c          167 g          307 t
ORIGIN      
        1 gagggctttt atatattaat cacaaatcac ttatcacaaa tcacaagtga ttaatcacaa
       61 atcacttgtg atttgtgatt cctaatgata caatattact atacaaaaaa agaatggggc
      121 gtagttatgg agaaggaaga actcaaaata cttgaagaat taagacgtat tttaaacagt
      181 aaaaatgaag cgattgttat cttaaacaat tattttaaag gtggtgttgg aaagtcaaaa
      241 ttatcgacta tgtttgctta cttgacagac aaatttaatt taaaagtttt aatgatcgat
      301 aaggacttac aagcaacatt gacaaaagac ttagcaaaaa catttaaggt agaattgcca
      361 cgtgttaatt tttatgaagg actgaaaaat ggaaacttgg cttcttctat tgttcatttg
      421 actgataatt tagacttgat ccctggcacg tttgatttga tgttactgcc aaaattaact
      481 cgctcatgga cttttgaaaa tgaaagtaga ttgcttgcta ctcttttagc acctttaaaa
      541 agtgactatg atctcattat tattgatact gtaccaacgc caagcgttta tacaaataat
      601 gcaatcgtgg caagtgatta cgttatgatc cctttacaag cagaagaaga aagtacaaac
      661 aacattcaaa actatatttc ctatttgatt gatttacaag aacaatttaa ccctggacta
      721 gatatgatcg gttttgttcc ttatttagtt gatacggaca gcgcaacgat aaaatcaaac
      781 ctggaagaac tgtacaagca acataaagaa gataacttgg ttttccaaaa tattatcaag
      841 cgaagtaata aagtaagtac ctggtctaaa aacggaatta cagaacacaa aggctatgac
      901 aaaaaagttt tatccatgta tgagaacgta ttttttgaaa tgcttgagcg aattattcaa
      961 ttagaaaacg aaaaagaata gaatcacaaa tcacaagtga ttaatcac
//
LOCUS       DAXQKX010000172          991 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.188, whole genome shotgun sequence.
ACCESSION   DAXQKX010000172 DAXQKX010000000
VERSION     DAXQKX010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..991
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.188"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            149..390
                     /locus_tag="ACF3MF_002896"
                     /pseudo
     CDS             149..390
                     /locus_tag="ACF3MF_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002425012.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
     gene            439..522
                     /locus_tag="ACF3MF_002897"
     CDS             439..522
                     /locus_tag="ACF3MF_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031556 - transcriptional attenuation by
                     ribosome [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HFE3928779.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            647..>991
                     /locus_tag="ACF3MF_002898"
     CDS             647..>991
                     /locus_tag="ACF3MF_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA adenine N-6-methyltransferase family
                     protein"
                     /protein_id="HFE3928780.1"
                     /translation="MKKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVF"
BASE COUNT          411 a          134 c          162 g          284 t
ORIGIN      
        1 tctttctcaa aataaacata aaagcccttt aaagagggct tttatatatt aatcacaaat
       61 cacttatcac aaatcactta tcacaaatca caagtgattt gtgattgttg atgataaaat
      121 aagaataaga agaaatagaa agaagtgagt gattgtggga aatttaggcg cacaaaaaga
      181 aaaacgaaat gatacaccaa tcagtgcaaa aaaagatata atgggagata agacggttcg
      241 tgttcgtgct gacttgcacc atatcataaa aatcgaaaca gcaaagaatg gcggaaacgt
      301 aaaagaagtt atggaaataa gacttagaag caaacttaag agtgtgttga tagtgcagta
      361 tcttaaaatt ttgtgtataa taggaattga agttaaatta gatgctaaaa atttgtaatt
      421 aagaaggagg gattcgtcat gttggtattc caaatgcgta atgtagataa aacatctact
      481 gttttgaaac agactaaaaa cagtgattac gcagataaat aaatacgtta gattaattcc
      541 taccagtgac taatcttatg actttttaaa cagataacta aaattacaaa caaatcgttt
      601 aacttctgta tttgtttata gatgtaatca cttcaggagt gattacatga aaaaaaatat
      661 aaaatattct caaaactttt taacgagtga aaaagtactc aaccaaataa taaaacaatt
      721 gaatttaaaa gaaaccgata ccgtttacga aattggaaca ggtaaagggc atttaacgac
      781 gaaactggct aaaataagta aacaggtaac gtctattgaa ttagacagtc atctattcaa
      841 cttatcgtca gaaaaattaa aactgaacat tcgtgtcact ttaattcacc aagatattct
      901 acagtttcaa ttccctaaca aacagaggta taaaattgtt gggagtattc cttaccattt
      961 aagcacacaa attattaaaa aagtggtttt t
//
LOCUS       DAXQKX010000173          983 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.189, whole genome shotgun sequence.
ACCESSION   DAXQKX010000173 DAXQKX010000000
VERSION     DAXQKX010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..983
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.189"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..939
                     /locus_tag="ACF3MF_002899"
     CDS             <1..939
                     /locus_tag="ACF3MF_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFE3928781.1"
                     /translation="STADMQKDAKDLSLKFLPYSLLISILFSAIISLIYAKSIKNNIQ
                     EIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDLEFKNKEILKLE
                     KLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIEIVDSLTKNISQ
                     ILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILDENVYIGKTALK
                     IILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIFDVKFDLNKENS
                     NGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
BASE COUNT          433 a           74 c          131 g          345 t
ORIGIN      
        1 tctacagctg atatgcaaaa agatgcgaaa gatttaagcc ttaaattttt accatattct
       61 ttattaatat caattttatt ttctgctatt atttctttaa tttatgcaaa atcaataaaa
      121 aataatatac aagaaataaa aattgttact gataaaatga tgaaacttga taaaaaaatg
      181 agtttaaaag ttagctctaa tgatgaagtt ggagaattaa aacaacaaat taatgatttg
      241 tattctactt tattaagaac aattgacgat ttggaattta aaaataaaga aattttaaaa
      301 ttagaaaagt taaaatatga cttttttaaa ggtgcatccc atgaacttaa aacccctctt
      361 gctagtctta aaataatact ggaaaacatg aaatacaata ttggaaaata taaagaaaga
      421 gatatttata ttaatgaatg tattgaaatc gttgatagtt taacaaaaaa tatttctcaa
      481 atattatcag ttcattctat agaaaatttg aataatgatg aagaatattt gaaaataaat
      541 gatacattag aagacatatt aaaaaagtat gaaatattag caaatcaaaa gaaaataact
      601 gtcaataatt atatattaga cgagaatgtt tatataggaa aaacagcttt aaagattatt
      661 ctatctaatt tgattagtaa tgcggtaaaa tatactgatg taaatggggt aattaatatt
      721 gggatagtta atgattggtt atatatagag aattcatacg gtaacaataa aatttcgaat
      781 atggataaaa tatttgatgt taaatttgat ttaaataagg aaaatagtaa tggattaggt
      841 ttatatattg taagtaatat tctgaataat tacaatatag aatataaagt attgcaggat
      901 gaagaatttt ttatctttaa aataaaaata ttttcttaat taagatataa ttttgcaata
      961 gttattgaaa aatagagact tat
//
LOCUS       DAXQKX010000174          970 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.190, whole genome shotgun sequence.
ACCESSION   DAXQKX010000174 DAXQKX010000000
VERSION     DAXQKX010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..970
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.190"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            65..>970
                     /locus_tag="ACF3MF_002900"
     CDS             65..>970
                     /locus_tag="ACF3MF_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HFE3928782.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     LKQRDTVIIACVIWGIINGYTSQRATYRAVCSVLFPNGDFPSRSRFTRLSSNLAYTIK
                     IIRYFFIKKLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTKKSYFYGLK
                     IHMIVTKTGFPITYSITNPGVHDVKVLETLSEEANLPNILGDKGYISHKIHEKLALKG
                     ITISVPPRKNMDKSEKLDHSLLGKQRKTVETVFSSLEKLGCQNFNSRSVKGLESRFES
                     ILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT          346 a          172 c          168 g          284 t
ORIGIN      
        1 gttggtaaat caacaaaaaa acgcatatag tagtctcaaa actcccaaga aatgaggact
       61 acatatgcgt tcatcaaaat atactgaaca ttatacagat acttttataa cattcaagga
      121 aattatgaga actgtttcta acatatacca caattgtgta ccagataaga ttaaaaaccg
      181 aagaaatact gatcaactga agcaacgcga tacagtgatt attgcttgtg ttatatgggg
      241 cataattaat ggctatacta gccaaagagc cacgtataga gcggtttgtt ccgtcttatt
      301 tcctaatggt gactttccta gtaggagtcg attcactcgc ttaagttcaa acttagctta
      361 cactatcaag attattcgat actttttcat caagaagctc accaaaggtg aactagtcgg
      421 aattatagat agttttccta gtccattatg taaaccagtt agaaatagac aagcaaaact
      481 attgaatcaa atagccaaag ttggctataa ctcaacaaaa aaatcttatt tttatggtct
      541 taaaattcat atgatcgtta ctaagactgg ctttccgatt acttactcaa tcacgaatcc
      601 aggtgtccat gacgtgaaag tgttagagac tttatcggaa gaagcgaatc ttcccaatat
      661 cctaggggac aaaggatata ttagccataa aatccatgaa aagcttgccc ttaagggcat
      721 tactatatcc gttccgccac gtaaaaacat ggataaatca gaaaaactag accacagctt
      781 acttggaaaa caaagaaaaa cagttgagac tgttttttct tccttagaaa aattaggttg
      841 tcaaaatttc aactcacgtt ctgttaaagg gctagagagt agatttgaaa gcatattact
      901 ggcttacagt gttctattaa gtcgagcaca acgacgtttt gaaggaactt tgagatattc
      961 tttaggatat
//
LOCUS       DAXQKX010000175          961 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.191, whole genome shotgun sequence.
ACCESSION   DAXQKX010000175 DAXQKX010000000
VERSION     DAXQKX010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..961
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.191"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            359..646
                     /locus_tag="ACF3MF_002901"
     CDS             359..646
                     /locus_tag="ACF3MF_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928783.1"
                     /translation="MNYPYFKVSASEETKEIFNNFYNQNKGVFGSKANMFRVMVSNLP
                     VLASPSNNKFNDPESIKFEQKISELESMISNEVIEKLDDIDQKLSYSLKNK"
     gene            666..>961
                     /locus_tag="ACF3MF_002902"
     CDS             666..>961
                     /locus_tag="ACF3MF_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928784.1"
                     /translation="MFKVYFPFQWLVKGILLVLLGLILFGSYLTIKARHFPEEKPIKI
                     VTKDLKIGETYQADGVELTFKNIEVTEKRNEFAQHDRVLQVTYTLINDTENPIRP"
BASE COUNT          370 a          154 c          173 g          264 t
ORIGIN      
        1 ctgctaaaca gattcactat caaatcagtc gcataatgaa tgacgatgta aaaatgtatc
       61 gtgctaaaaa ggattatgaa ttcacacaac aaatgattga aaatcagcaa aaaaggcaac
      121 aaaattttga aatggaattc tgaatgggct tgttagtgga ctttccagtt ttttgcctat
      181 gaagagttgc ttggaaagaa gcagttttta ggacatacgc cagctaccca tctacttgcc
      241 agtcaatccg ccccgctcac gctaggctac tttctggcaa gtcagatggt gggtaaatct
      301 ctgagggagc aagctcccta cagactccct cccaaaaaaa gaaaggtgga agaaaaaaat
      361 gaactatcca tattttaaag tctcggcttc agaagaaact aaagaaatat tcaacaattt
      421 ttacaaccaa aacaaaggag tttttggttc aaaggcaaat atgtttcgtg ttatggtttc
      481 gaatttacca gtgttagcta gtccatcaaa taataaattt aatgatcctg aaagcattaa
      541 atttgaacaa aaaatttcag aactagaatc aatgataagt aatgaagtaa ttgaaaagct
      601 ggatgacatt gatcaaaagt tatcgtattc tctaaaaaac aaataaaaaa cggaggagaa
      661 aaaagatgtt taaagtttac ttcccgtttc agtggctcgt taaaggaatt cttttagtgc
      721 tactaggatt gattcttttt ggaagttatc taacaattaa agccagacat tttccagaag
      781 aaaagccaat aaaaattgta acaaaagatt taaaaatagg tgaaacttat caggcagatg
      841 gggttgaact aacatttaaa aatattgaag tgaccgaaaa aagaaatgaa tttgcacaac
      901 atgatcgtgt attacaagtg acctatacac ttataaatga tacagaaaat ccgatacgtc
      961 c
//
LOCUS       DAXQKX010000176          945 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.193, whole genome shotgun sequence.
ACCESSION   DAXQKX010000176 DAXQKX010000000
VERSION     DAXQKX010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..945
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.193"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..256)
                     /locus_tag="ACF3MF_002903"
     CDS             complement(<1..256)
                     /locus_tag="ACF3MF_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFE3928785.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGLNEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGG"
     gene            complement(267..464)
                     /locus_tag="ACF3MF_002904"
     CDS             complement(267..464)
                     /locus_tag="ACF3MF_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HFE3928786.1"
                     /translation="MILPDKYYQVIKWTVLTVLPAASALVAMLGKAYGWNGTDMTVLT
                     INAVATFLGVITGVSAYNLKK"
     gene            complement(480..722)
                     /locus_tag="ACF3MF_002905"
     CDS             complement(480..722)
                     /locus_tag="ACF3MF_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin XhlA family protein"
                     /protein_id="HFE3928787.1"
                     /translation="MKDEAIQDVVERLVRIETKLDNYELLREKAESAKDRADQAYSIA
                     LNNAEDIKEMKANNKWSWGYMIGLGITIIGYFLTKL"
BASE COUNT          273 a          208 c          139 g          325 t
ORIGIN      
        1 ttccaccgtc tcccacaata taagcagtat aagcactagt ccatgaacgt tgcatatatt
       61 gcgcttcatt gcgtcctgtt gctgtttcat tagccgtttc atgcagtaaa atgtactgat
      121 tatttgctac ttgtgagcta ccttcgttta ggcccaaatt aaattcattg ttaatcgtat
      181 aggcgaaccc attaattggc aataaaaaaa gagccgttaa taggctcatc gcagtaatag
      241 taattttctt tttcatttgt ttcctcctat tttttcaaat tataagccga cacaccagtg
      301 ataacgccta aaaacgtggc tactgcattg atagtcagaa ctgtcatatc tgttccattc
      361 catccatagg ctttgcctaa catggctact aaagcagatg cagctggtaa tactgttaaa
      421 accgtccatt taatgacttg ataatactta tcgggtaaaa tcatttcttc tcacctcctt
      481 tacaatttag tcaagaaata gccaatgatc gtaatgccta aaccgatcat gtaaccccac
      541 gaccatttat tattggcttt catttctttg atatcttccg cattattaag cgcaatagaa
      601 tatgcctgat ccgctctatc ttttgcactt tccgcttttt cgcgtaataa ttcgtaatta
      661 tccagtttcg tttcaatacg cactaagcgt tctaccacgt cttgtattgc ttcgtctttc
      721 aaccaactat cctcctttca ttgcaaaata aaaaacaccc tcctttgagc gtgttgatag
      781 caaaattata aatattgtat taatcagata gtctagtcaa gactaaagta cggcaagatg
      841 taaattgtaa aattccattt gcaacgccga tttcagtacg catatttagt acatcgttta
      901 cttctaaatc agttacaatg tttccgctag ctgcaaatct atttt
//
LOCUS       DAXQKX010000177          919 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.194, whole genome shotgun sequence.
ACCESSION   DAXQKX010000177 DAXQKX010000000
VERSION     DAXQKX010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..919
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.194"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..869
                     /locus_tag="ACF3MF_002906"
     CDS             <1..869
                     /locus_tag="ACF3MF_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HFE3928788.1"
                     /translation="VQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQF
                     CTGKDSQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHV
                     RRKFFEAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIA
                     FYEWMATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRK
                     NWLHSTSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLP
                     WNKDVQQHFSRN"
BASE COUNT          296 a          167 c          201 g          255 t
ORIGIN      
        1 cagtgcaaaa cgcgttagac cctttaggag aacgattaag agtctatctt aatcaagaag
       61 agattctaca cggggatgaa acaagttatc gtgtgattga aagtgccaaa acagatacct
      121 attactggca gttttgtaca ggaaaagaca gtcagcatcc catcgtttat tatcaccacg
      181 acgaaagtcg tgctggagat gttccgaaaa cttttctcaa ggagtttaca gggtatttac
      241 actgtgacgg ctatagcggg tataatgccg tggaaagtgt acgacttgtc tattgtttcg
      301 cgcatgttcg gcggaaattt ttcgaagcaa ttccaaaagg aaagaaaaac acggatattc
      361 ccgcagctca agcagtcaaa caattggata aatggtttgt cctagaaaag aaatggaaag
      421 acttttctcc tgagaagcga ttaagctgtc ggcaacaaga actgcgtcca ttatttattg
      481 ctttttatga gtggatggca acgatagatc ctgttgcaaa atccaagttg gatgcagccg
      541 ttcaatatgc gtgtaaacta cgaagtggtt ttgaacctat ttttgaagat ggtcgtttag
      601 aactcacaaa taatcgtgcg gagcgaaata tcaaagagct ggtgatagga cggaaaaatt
      661 ggttgcattc cacaagtctt gaaggagcac gaacttcagg aatcattctg agtgtatata
      721 aaacagcaga acttaacgga ttgaatcctg taaagtatct agagtttcta tttgataaga
      781 taccaaatct tcccgtactt tcagcagaaa ctttagatca actgttgcct tggaacaagg
      841 atgtacaaca acatttttct cgtaactaaa aacgccaaac attcccgatt ctattctata
      901 ggtcgggtta tttgacgta
//
LOCUS       DAXQKX010000178          917 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.195, whole genome shotgun sequence.
ACCESSION   DAXQKX010000178 DAXQKX010000000
VERSION     DAXQKX010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..917
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.195"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..>917
                     /locus_tag="ACF3MF_002907"
     CDS             <1..>917
                     /locus_tag="ACF3MF_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFE3928789.1"
                     /translation="QKVEVTSQRLANAKKYYGENSTEVQKLERELINQQTAQQRLSNE
                     IDKTSNTLAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQVTAGQSASESE
                     KLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAKLNDAEREFEEL
                     GQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVDSANSVGSSQSK
                     IQANFGLTKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGDLNNQDLQNITE
                     QAMVLENTMGADMDETLRGVNGLMVNFGL"
BASE COUNT          348 a          149 c          200 g          220 t
ORIGIN      
        1 caaaaagttg aagtaactag ccaacgttta gccaatgcca aaaaatatta tggagaaaat
       61 tccaccgaag ttcagaaact tgagagagaa ctgattaacc aacaaacagc gcaacaacgt
      121 ttgtcaaacg aaattgataa aacgagtaat acactagctc aagcaaaagg cgaaatacag
      181 acgtacgagt ctacaatgca acagttggat agtgaacaaa aaaatgttca agctagtgct
      241 tctctgattg aatccgaata caaaaaatgg caagtaactg ctggtcaatc agcttctgaa
      301 tccgagaaat tagcgaaagc ccaagaatat gtttctcaac aatctgaaaa tgcagagaaa
      361 acgatagata tcctgagacg acagttagaa gctacacagt ctgagtttgg cgctacatcc
      421 acagaagcaa tgcagatgga ggcgaagctt aatgatgctg aacgtgaatt tgaagagtta
      481 ggacaagctg ctaaaaatgt agatacaact aacttggacg atatcggaag caaaatagat
      541 atgaataatt taatggaagc ttctgacgtt ttaagcgaca ttggcgataa gcttacagaa
      601 ttagggaaac aagcagtgga ctctgctaac agtgtaggta gttcccagag taaaatacaa
      661 gctaattttg gtttgactaa acaagaggct gaagaattaa cgaatgtagc cagagacatt
      721 tattataaag gttttggaga atcgttagat cagtccacag atgcattgat tttggtaaag
      781 cgtaatttag gcgatttaaa taatcaagat ttacaaaata ttacggaaca agctatggtc
      841 ctagaaaaca ccatgggcgc tgatatggat gaaacgttac gtggtgtaaa tggcttaatg
      901 gtcaacttcg gattgag
//
LOCUS       DAXQKX010000179          917 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.196, whole genome shotgun sequence.
ACCESSION   DAXQKX010000179 DAXQKX010000000
VERSION     DAXQKX010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..917
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.196"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..>917
                     /locus_tag="ACF3MF_002908"
     CDS             <1..>917
                     /locus_tag="ACF3MF_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFE3928790.1"
                     /translation="QKVEVTSQRLANAKKYYGENSTEVQKLERELINQQTAQQRLSNE
                     IDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQATAGQSASEAE
                     KLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAKLNDAEREFEEL
                     GQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVDSANSVGSSQSK
                     IQANFGLSKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGDLNNQDLQNITE
                     QAMVLENTMGADMDETLRGVNGLMVNFGL"
BASE COUNT          347 a          149 c          201 g          220 t
ORIGIN      
        1 caaaaagttg aagtaactag ccaacgttta gccaatgcga aaaaatatta tggagaaaat
       61 tccaccgaag ttcagaaact tgaaagagaa ctgattaatc aacaaacagc gcaacaacgt
      121 ttgtcaaacg aaattgataa aacgagtaat gcactagctc aagcaaaagg cgaaatacag
      181 acgtacgagt ctacaatgca acagttggat agtgaacaaa aaaatgttca agctagtgct
      241 tctctgattg aatccgaata caaaaaatgg caagcaactg ctggtcaatc agcttctgaa
      301 gccgagaaat tagcgaaagc ccaagaatat gtttctcaac aatctgaaaa tgcggagaaa
      361 acgatagata tcctaagacg acagttagaa gctacacagt ctgaatttgg cgctacatcc
      421 acagaagcaa tgcagatgga agcgaagctt aatgatgctg aacgtgaatt tgaagagtta
      481 ggacaagctg ctaaaaatgt agatacaact aacttggacg atatcggaag caaaatagat
      541 atgaataatt taatggaagc ttctgacgtt ttaagcgaca ttggcgataa gcttacagaa
      601 ttagggaaac aagcagtgga ctctgctaac agtgtaggta gttcccagag taagatacaa
      661 gctaattttg gtttgtctaa acaagaggct gaagaattaa cgaatgtagc cagagacatt
      721 tattataaag gttttggaga atcgttagat cagtccacag atgcattgat tttggtaaag
      781 cgtaatttag gcgatttaaa taatcaagat ttacaaaata tcacggaaca agctatggtc
      841 ctagaaaaca ccatgggcgc tgatatggat gaaacgttac gtggtgtaaa tggcttaatg
      901 gtcaatttcg gcttgag
//
LOCUS       DAXQKX010000180          905 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.197, whole genome shotgun sequence.
ACCESSION   DAXQKX010000180 DAXQKX010000000
VERSION     DAXQKX010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..905
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.197"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..336
                     /locus_tag="ACF3MF_002909"
     CDS             <1..336
                     /locus_tag="ACF3MF_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFE3928791.1"
                     /translation="RNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            337..885
                     /locus_tag="ACF3MF_002910"
     CDS             337..885
                     /locus_tag="ACF3MF_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928792.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
BASE COUNT          365 a          123 c          195 g          222 t
ORIGIN      
        1 agaaatgcga tgcaatatct tgagtatatg gacttttttg tgaaagaatt tgatacaaat
       61 ttatatgttg ctggtgttat tcctttcatg ttggaaagcg gtgacgcagt agatcaggaa
      121 atgtataaac aagcccaaga gatttatggg gaacatttga ttaaaaatgt tgtactcaaa
      181 aatgcgcgct taaaacgata cgacggatca ggtattacga tggagaagac aaagaaaggt
      241 ctcttaaaac aatgggatcg caaaagccac gaattattta tcagtatttt gaaagaattg
      301 gaagaacacg agaattggta tgcggaggtg gagtaattgg ctgacatcaa aggacttgat
      361 atttttggga acaacaaagg actcgccaaa ataaaaaaag aagcagaagc aaagaaaaag
      421 cagcaagcaa ttacaccatc tgaaaataag caattagaag tgcaccaagt tcaagaaata
      481 aaaacttcct ccaatgttga aagacagagt agaggaagaa caaaaaaagt tggcgcacca
      541 atcagaaagt ttgataaggt ttattccacc aagcatcctt taaaactgtc gactttgtta
      601 aatgcgactt ccagagtttt agtagaaaag tatgagacta atatgacaag agatgaattg
      661 cttagaaaag ctttagatga gtatattaaa cagaatctta cgcaagaaga taagcaagat
      721 ttgtttaatg acgtggtgaa agaactagac ttgttcagag aaaaatatcc aattgttcca
      781 gaattagatg atcgtggaga aataataaga actaccagtc agataaaaca agataccgaa
      841 gactcactgc gcaaagggtg gggaatgaat aataaagtta gataataatc aaagaagaac
      901 taagt
//
LOCUS       DAXQKX010000181          900 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.198, whole genome shotgun sequence.
ACCESSION   DAXQKX010000181 DAXQKX010000000
VERSION     DAXQKX010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..900
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.198"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            28..>900
                     /locus_tag="ACF3MF_002911"
     CDS             28..>900
                     /locus_tag="ACF3MF_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFE3928793.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDEFFIQSVASKRNN"
BASE COUNT          312 a          155 c          169 g          264 t
ORIGIN      
        1 ccaaagaatt ataaggagtg agtacaaatg acctataccc atcttacaac ggatgaactt
       61 gtaataatag agtcttattt caaaatgaat caatctgttg ctaaaactgc ccattgcttg
      121 aatcgttcaa gacaaacgat ccataaagta tatctgttct tcaagcaagg aaaatcagcc
      181 ttagaatatt atcaacagta taagaaaaac aaatcaaact gtggtagacg tccgcttgtt
      241 ttacccgagg aacaatcaga atatattcaa agaaaggttg ttcaaggatg gacacccgat
      301 gtgattgttg gtcgtgcagc gtttcctatt agttgttctg ctcgtaccat ttatcgtatg
      361 ttcaaaaagg ggctatttga ttcttctgac ttaccgatga aaggcaagcg taaaccgaat
      421 ggacatcaag aaagacgtgg aaaacaaact ttccgccgct ctattcatga acgtgaaaag
      481 gattatagcc aattctcaaa tgagtttggt caccttgaag gtgacactat cgtaggtctg
      541 aaacataaaa gtgctgtaat taccttagtt gaacgattat caaaagttat catcacattg
      601 aaaccgtgtg gtagacaagc gattgatatt gaaaaaaaat taaatcaatg gtttgaatct
      661 gtaccgaaaa acctattcaa atccatcact tttgattgtg gaaaggaatt ttcaaattgg
      721 aaacagatca gtaatgtcaa tgatattgcc atttatttcg ctgatccagg aacgccgtct
      781 caaagaggcc taaacgagaa ttctaacgga ttgttacgta gagatggttt attgaaatct
      841 atggatttca attcagtaga tgaatttttt attcaatctg tcgcatctaa acgaaataat
//
LOCUS       DAXQKX010000182          865 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.199, whole genome shotgun sequence.
ACCESSION   DAXQKX010000182 DAXQKX010000000
VERSION     DAXQKX010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..865
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.199"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..208)
                     /locus_tag="ACF3MF_002912"
     CDS             complement(<1..208)
                     /locus_tag="ACF3MF_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFE3928794.1"
                     /translation="MDTITPTNFKENIGKVLQEVVHSNSEIEITRDSKNGLNDGVIMI
                     SKRKWELLQEELYLQRTGTWAYVSD"
     gene            complement(307..621)
                     /locus_tag="ACF3MF_002913"
     CDS             complement(307..621)
                     /locus_tag="ACF3MF_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928795.1"
                     /translation="MAEENKVVPFETLVINKEEFEQLFLDFFIQYDMIYDFSSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSQTFEIDPDYYQPQEVFREFRNKIIGFSQT
                     TK"
BASE COUNT          284 a          172 c           90 g          319 t
ORIGIN      
        1 aatcagatac ataagcccat gtacccgttc gttgtaaata aagttcttct tgtaacaact
       61 cccattttct cttagaaatc ataatgacgc catcgttcaa tccattttta gaatccctag
      121 taatttctat ttcagaattt gaatgaacta cttcttgcaa cactttacct atattttctt
      181 tgaagtttgt tggagtaata gtatccaaaa tgaatacctc tcttctctat acctctatta
      241 tgaagtgccc ataaaataaa gcaagcgttg aggaataatt ctatcaacac ttgctttatt
      301 aagctttcat tttgtagttt gactaaaacc aataatctta tttctaaact ctcgaaaaac
      361 ttcttgtggt tgataatagt ctggatctat ttcaaatgtt tgtgagaata attcattgaa
      421 tttttctact gaaataatga ttttaccatt cttctctcga ctgttttcta ttatttctgc
      481 ttctaattca aataaatcta gtgacgaact aaaatcataa atcatgtcat attgaataaa
      541 aaaatcaaga aaaagttgct caaactcttc cttatttatc actaatgttt caaacggaac
      601 aactttattt tcctcagcca ttctcccagt tccattttca aaaatcacaa aactgatatt
      661 accttaaaaa ctactaacaa aataaaactt ataaagtaaa tggcaaccca actatgtaac
      721 cattctctct acgtactacg atttggtagt cctgcctttc aatcggtaat tcataatagt
      781 aatttactgt ttcttctttg ccactttcaa tatactctgg attatccaat atcatatcat
      841 actcataaag ttcttcacca tcctt
//
LOCUS       DAXQKX010000183          863 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.200, whole genome shotgun sequence.
ACCESSION   DAXQKX010000183 DAXQKX010000000
VERSION     DAXQKX010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..863
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.200"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..>863)
                     /locus_tag="ACF3MF_002914"
     rRNA            complement(<1..>863)
                     /locus_tag="ACF3MF_002914"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          186 a          271 c          197 g          209 t
ORIGIN      
        1 tcttgaggtg ggcttcacac ttagatgctt tcagcgttta tcccttccct acatagctac
       61 ccagcaatgc ccttggcaga acaactggta caccagcggt aagtccatcc cggtcctctc
      121 gtactaagga cagctcctct caaatttcca acgcccgcga cggataggga ccgaactgtc
      181 tcacgacgtt ctgaacccag ctcgcgtgcc gctttaatgg gcgaacagcc caacccttgg
      241 gaccgactac agccccagga tgcgacgagc cgacatcgag gtgccaaacc tccccgtcga
      301 tgtggactct tgggggagat aagcctgtta tccccagggt agcttttatc cgttgagcga
      361 tggcccttcc atgcggaacc accggatcac taagcccgac tttcgtccct gctcgacttg
      421 ttggtctcgc agtcaagctc ccttctgcct ttacactctt cgaatgattt ccaaccattc
      481 tgagggaacc tttgggcgcc tccgttacct tttaggaggc gaccgcccca gtcaaactgc
      541 ccatctgaca ctgtctccca ccacgattag tggtgcgggt tagagtggcc ataacgcagg
      601 ggtagtatcc caccagcgcc tccatcgaaa ctagcgttcc gatttctacg gctcctacct
      661 atcctgtaca tgcggtacag acactcaata tcaaactaca gtaaagctcc atggggtctt
      721 tccgtcctgt cgcgggtaac ctgcatcttc acaggtacta aaatttcacc gagtctctcg
      781 ttgagacagt gcccaaatcg ttacgccttt cgtgcgggtc ggaacttacc cgacaaggaa
      841 tttcgctacc ttaggaccgt tat
//
LOCUS       DAXQKX010000184          851 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.201, whole genome shotgun sequence.
ACCESSION   DAXQKX010000184 DAXQKX010000000
VERSION     DAXQKX010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..851
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.201"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..>851)
                     /locus_tag="ACF3MF_002915"
     rRNA            complement(<1..>851)
                     /locus_tag="ACF3MF_002915"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          175 a          271 c          188 g          217 t
ORIGIN      
        1 catctcacga cacgagctga cgacaaccat gcaccacctg tcactttgcc cccgaagggg
       61 aagctctatc tctagagtgg tcaaaggatg tcaagacctg gtaaggttct tcgcgttgct
      121 tcgaattaaa ccacatgctc caccgcttgt gcgggccccc gtcaattcct ttgagtttca
      181 accttgcggt cgtactcccc aggcggagtg cttaatgcgt tagctgcagc actgaagggc
      241 ggaaaccctc caacacttag cactcatcgt ttacggcgtg gactaccagg gtatctaatc
      301 ctgtttgctc cccacgcttt cgagcctcag cgtcagttac agaccagaga gccgccttcg
      361 ccactggtgt tcctccatat atctacgcat ttcaccgcta cacatggaat tccactctcc
      421 tcttctgcac tcaagtctcc cagtttccaa tgaccctccc cggttgagcc gggggctttc
      481 acatcagact taagaaaccg cctgcgctcg ctttacgccc aataaatccg gacaacgctt
      541 gccacctacg tattaccgcg gctgctggca cgtagttagc cgtggctttc tggttagata
      601 ccgtcaaggg atgaacagtt actctcatcc ttgttcttct ctaacaacag agttttacga
      661 tccgaaaacc ttcttcactc acgcggcgtt gctcggtcag actttcgtcc attgccgaag
      721 attccctact gctgcctccc gtaggagttt gggccgtgtc tcagtcccaa tgtggccgat
      781 caccctctca ggtcggctat gcatcgtggc cttggtgagc cgttacctca ccaactagct
      841 aatgcaccgc g
//
LOCUS       DAXQKX010000185          789 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.204, whole genome shotgun sequence.
ACCESSION   DAXQKX010000185 DAXQKX010000000
VERSION     DAXQKX010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..789
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.204"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..782
                     /locus_tag="ACF3MF_002916"
     CDS             <1..782
                     /locus_tag="ACF3MF_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFE3928796.1"
                     /translation="DMLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNG
                     VSLARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGE
                     LISLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKL
                     IKNNKDKYIFISKNGNPISIQAYNQSLRAVSKELNIDKKVSSHMLRHSHISLLTELGI
                     PLKAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
BASE COUNT          340 a          106 c          102 g          241 t
ORIGIN      
        1 aagatatgct agattactac tattttgaaa aaaatttatc atataattat gtaatacatt
       61 taaaaacttt tacaggaatg atttttaaat tcgccaaccg tcgatatgga ttaaaatata
      121 atcccgtaaa tggggtttct ttagcaagaa aacctaagac aaacgaagaa ataaaaaaag
      181 aaaaagatgg ttatttatca aaagaagaag ttcaaatgat tgctagtaaa caaaaaagtt
      241 cacatcaaca gtcacgttat tctttaatta ctaaattttt gtttttaact ggactacgtt
      301 atggtgaatt gatatctttg actgaatctg attatgatgg taataaaatt acggtttctg
      361 gtacttatga ttacgagtta aaaattaaaa caacaactaa aaatacaggt tcttatagaa
      421 ccattgaatt atcaagtaat gctaaagaaa tcatagatca attaattgaa gaaaacaaat
      481 taattaagaa taataaagat aaatacattt tcatctctaa aaatggtaac ccgatatcta
      541 ttcaagcata taatcaatct ttaagagcag tatccaaaga attaaacata gataaaaaag
      601 tttcttctca catgttaagg cattcccaca tttctctact tacagaatta ggaatcccat
      661 taaaagccat tatggatcgt gtaggacatg aagattcaaa aacaacatta aagatttata
      721 ctcatacaac taaaaatatg caaaatcaac tagtagaaaa actaggaaaa atagaaattt
      781 aaattgccc
//
LOCUS       DAXQKX010000186          785 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.205, whole genome shotgun sequence.
ACCESSION   DAXQKX010000186 DAXQKX010000000
VERSION     DAXQKX010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 785)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 785)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..785
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.205"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            1..785
                     /locus_tag="ACF3MF_002917"
                     /pseudo
     CDS             1..785
                     /locus_tag="ACF3MF_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="internal stop; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
BASE COUNT          276 a          142 c          143 g          224 t
ORIGIN      
        1 caaaccatgt ccaacatgac taaagtgctg actgaagaag taaatgcatt taaagttaga
       61 actctaaatg ataagtatgt cgctattttc atggatgcta cttatattcc tttaaaacgg
      121 caaaccgtct ccaaagaagc aatctatatt gccattggta tacgagaaga cggcactaaa
      181 gaagtactaa gttatgcgat tgctccgact gaatcgacct acgtttggaa tgagttgtta
      241 caggacattt actccagagg ggttcatgat gtcttactgt ttattaccga tggcttaaaa
      301 ggcatgaaag atacgattca ccagatttat cctaaagcta aataccaaca ttgctgtgtt
      361 cacgtttccc gtaatattgc tcataaagta cgtgtcaaag atcgaaaaga aatctgtgat
      421 gattttaagg ctgtttatca agctagctca aaggaagagg caaatacctt tttagggagt
      481 atgattgaga agtagcaaaa aacttatcct aaagtgacgc agtcactgat aaaaaatcaa
      541 gatttattga ctttttatga gtttccgcct ggtatccgcc gaagcattta ctcaactaat
      601 ttaatcgaat ctttcaagaa acaaatcaag aaatacagcc gcagaaaaga gcagtttcaa
      661 aatgaagaat cactagagcg tttcctagta tccatctttg atacatacaa tcaaaaattc
      721 ttaaatagaa gccataaagg cttccaacaa gtgacggata cattagcttc aatgtttact
      781 gagta
//
LOCUS       DAXQKX010000187          778 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.206, whole genome shotgun sequence.
ACCESSION   DAXQKX010000187 DAXQKX010000000
VERSION     DAXQKX010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..778
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.206"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..>778
                     /locus_tag="ACF3MF_002918"
     CDS             <1..>778
                     /locus_tag="ACF3MF_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HFE3928797.1"
                     /translation="ISGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEV
                     KAEPIFNDIRKSVLNKYDSGTEKITATQAWQNAKALAKPAIPSQFSFSSLVDTLANVK
                     IEKANFLEFFGGKEGSILDRFHGEFLKDNNTLHHEKRLGTDHKIKAIYTKNLTGLDLE
                     IDAQSVLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVAT
                     LREAAKEWLKTNVDKQKPQVSGSIELVPLRHQRGYEKFVDL"
BASE COUNT          280 a          115 c          161 g          222 t
ORIGIN      
        1 caataagcgg aactaatgca gatttgattg tagaaggacg tattattcag tgttatgtag
       61 atgaaaatcg agcaaaacag cgtctacgga tttattatgc aaaaacttct gtaataggca
      121 atacgataga agtaaaagct gaacctattt tcaatgatat aagaaaatcg gtgttgaata
      181 aatatgacag cggaacagaa aaaatcactg ctactcaggc atggcaaaac gcaaaagctt
      241 tagcgaaacc agctatccct tcgcagtttt ctttctcgtc attagtagat acgcttgcta
      301 atgtgaagat agaaaaagcg aattttttag aattctttgg tggaaaagag ggatctattc
      361 tagatcgatt tcatggggaa tttcttaaag ataataacac attacatcat gaaaaaaggc
      421 taggtacgga tcataaaatc aaagcgattt atactaaaaa tttaactggt cttgacttag
      481 agatagatgc tcaaagcgtt ttagttggag tttatccatt cattagcagt tcttcagaag
      541 gagaagacga gatcactcta ccagaagaag tcattttcac ggattacgtg gatgattatc
      601 ctgctggata tgtttctttt gttgatttta aagacaaagc gactgatgta gccacattaa
      661 gggaagctgc taaagaatgg ttgaaaacga acgtagacaa acaaaaacca caagtgagtg
      721 gttcgattga attagtacca ttgagacatc aaagaggtta tgaaaaattt gttgatct
//
LOCUS       DAXQKX010000188          776 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.207, whole genome shotgun sequence.
ACCESSION   DAXQKX010000188 DAXQKX010000000
VERSION     DAXQKX010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..776
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.207"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..741
                     /gene="thyX"
                     /locus_tag="ACF3MF_002919"
     CDS             <1..741
                     /gene="thyX"
                     /locus_tag="ACF3MF_002919"
                     /EC_number="2.1.1.148"
                     /inference="COORDINATES: protein motif:HMM:TIGR02170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050797 - thymidylate synthase (FAD)
                     activity [Evidence IEA];
                     GO_process: GO:0006231 - dTMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent thymidylate synthase"
                     /protein_id="HFE3928798.1"
                     /translation="FNTIEGNYGLHGLTDEVGASDGQVVALTAIRTCYSANKPTEIVA
                     KEGAKYFGSKASDGGAGTDADRLFRHIFASKHTSTLEHISFTFAIEGVSRALLAQLTR
                     HRVGFSFSVQSQRYVRMGSDDRSGGFDYVIPDKVKTCTKELDLYGGGDVPFSAREIFE
                     DALRELQDAYDYLREMGVPAEDARAVLPNAAATNLVMTANLTALLSFYSKRKKGRGAQ
                     AEITELAEALRREVVDVEPWTDQFFEEV"
BASE COUNT          200 a          185 c          225 g          166 t
ORIGIN      
        1 tttaacacta tagaagggaa ctacggtctt cacggattaa cagacgaggt tggggcatct
       61 gatggccaag tggtcgccct aaccgcaatc agaacgtgct acagcgccaa taagccgacc
      121 gaaatcgtcg caaaggaagg cgccaagtat ttcggttcca aagcgtcaga tggcggcgca
      181 ggaacggatg ctgaccgact attccggcac atcttcgcat ccaaacacac gtcgacgttg
      241 gagcatatct cgttcacctt tgcgattgag ggcgtcagcc gggcgttatt ggcgcagctt
      301 acacggcatc gcgtaggttt tagctttagc gtccagtcac agcggtatgt gcggatgggg
      361 agcgacgata gatcgggcgg gttcgattac gtgatcccgg ataaggttaa gacctgcacg
      421 aaagaattag atttatacgg aggaggggac gttcctttta gcgcgagaga gatattcgaa
      481 gatgctctac gtgagctaca ggatgcttac gattacttgc gggaaatggg cgttccagcc
      541 gaagatgctc gtgccgtcct accgaatgcc gccgcaacga atctcgtaat gactgcgaac
      601 ctgactgcgt tgctttcgtt ctattccaaa cgtaaaaaag gacgcggcgc acaggcagaa
      661 atcaccgaat tagccgaagc gctaagacgc gaagtggtcg acgtggagcc atggacggac
      721 cagtttttcg aggaggtgta agcatcggta tactaacgaa tctagcgatg tcaacg
//
LOCUS       DAXQKX010000189          763 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.208, whole genome shotgun sequence.
ACCESSION   DAXQKX010000189 DAXQKX010000000
VERSION     DAXQKX010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..763
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.208"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            56..>763
                     /locus_tag="ACF3MF_002920"
     CDS             56..>763
                     /locus_tag="ACF3MF_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HFE3928799.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKNCQVSLTTVIRTLKEFKSYLPKQSK
                     RILPRVLMVDEFRSHASIEDKMSFICADGETGQLIDVLPTRKLPRLTSYFLGCANPEE
                     VKFLVTDMNAAYFQLTKR"
BASE COUNT          249 a          143 c          149 g          222 t
ORIGIN      
        1 tctctagtat gattaaatca cgacaaaata aacaactgag aggacgatat gctatatgaa
       61 tgattctatc aaaaaaatgc tgcgattaat agagaaagat ttgatgatta cagaggtctc
      121 ttacgagacc tttcagaaga aaaagacgtt gatcgtcgat gctgttttct cacctgctcc
      181 ccatacctgt agaaattgtg gttctactgt ggtagatgga aacgggaaag taattgtagt
      241 gaaaaatggg aagaaggaaa cgattgtccg ctttgaacaa tacaatcaca tgcctttggt
      301 tatgcgctta aaaaagcagc gctatacctg taaaaactgt cgaacccatt ggacggctca
      361 aagttatttt gttcaaccca gacattcaat cgcgaatcat gtcagatata aaattgcttc
      421 tttactgact gaaaaagtat ctttatcttt tattgcgaaa aattgtcagg tatctttgac
      481 caccgttatt cgtacgttga aagagtttaa aagctactta ccaaagcaat ctaagaggat
      541 tctccccaga gtattgatgg ttgatgaatt tcgttcgcac gcttccatag aagataaaat
      601 gagctttatt tgcgcagatg gcgaaacagg acaattaatt gatgtcttgc ctacgcgtaa
      661 attgcctcga ttaacaagct atttcttagg ctgcgctaat cctgaagaag taaaattttt
      721 agtcacagac atgaacgccg cctacttcca gcttaccaaa cgt
//
LOCUS       DAXQKX010000190          750 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.209, whole genome shotgun sequence.
ACCESSION   DAXQKX010000190 DAXQKX010000000
VERSION     DAXQKX010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..750
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.209"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..453
                     /locus_tag="ACF3MF_002921"
     CDS             <1..453
                     /locus_tag="ACF3MF_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011475946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HFE3928800.1"
                     /translation="IAMSGDAIFMPANAMMMIHNPWTLAQGNADELRKQADDMDRIRE
                     SLVEAYLGKAGEKLDRDRLIALLDAETWLTAQECLELGLCDSIEAPKQVAAKVDTKLF
                     ASYRNTPDALLNQTEEDEKQAERERVEREQLIAEAQTNLLKLKNGGII"
     gene            453..>750
                     /locus_tag="ACF3MF_002922"
     CDS             453..>750
                     /locus_tag="ACF3MF_002922"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928801.1"
                     /translation="MELFDLKANLNTVGTQLASVEKEIMNKAADPNASIEDVRALKQK
                     KDDLKERMDILQNQHDSLEREQKAKIQASLQQAKAGVSEGLTSSDPKTQKTSAKA"
BASE COUNT          258 a          158 c          178 g          156 t
ORIGIN      
        1 atcgcaatgt ccggtgacgc tatttttatg cccgcaaacg cgatgatgat gattcacaat
       61 ccgtggacct tagcgcaggg aaacgcggac gaactccgca agcaggccga tgacatggat
      121 cgcattcgcg aaagtcttgt cgaggcttat ctcggaaagg caggcgaaaa gcttgatcgt
      181 gatcgtttaa tcgctctttt ggacgcagaa acgtggctta cagcgcagga atgcctcgaa
      241 ttagggcttt gcgacagtat cgaagctcca aaacaagtgg ctgcgaaagt agatacgaag
      301 ttattcgcga gttaccggaa tactccggac gctttactta atcaaacgga agaagacgaa
      361 aagcaggcgg aaagagagcg cgtggaacgc gagcaactca tcgcggaagc acaaacaaac
      421 ttactaaaac tcaaaaatgg gggaattatt taatggaact atttgatctg aaggctaact
      481 taaatactgt aggtactcaa ttagcatctg tagaaaagga aatcatgaat aaagcggctg
      541 atccaaacgc ttctatcgaa gatgtaagag ctcttaaaca gaaaaaagac gatcttaaag
      601 agcgtatgga tattctacaa aaccaacacg attctttaga gcgcgagcaa aaagctaaaa
      661 tccaagcaag cttacaacaa gctaaagcag gcgtatccga aggtcttaca agctctgatc
      721 caaagactca aaaaacatcg gctaaagcag
//
LOCUS       DAXQKX010000191          747 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.210, whole genome shotgun sequence.
ACCESSION   DAXQKX010000191 DAXQKX010000000
VERSION     DAXQKX010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..747
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.210"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(221..>747)
                     /locus_tag="ACF3MF_002923"
     CDS             complement(221..>747)
                     /locus_tag="ACF3MF_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928802.1"
                     /translation="LIYKIIEDDKQTELNMCYFDREQDFFYYGGMGGGSIVPKINLVE
                     LDVNNYRELYVFNSLDVEIPMKQMKNIDIHILPSESCQIEYSIEYFYKGKNIKKCDKC
                     FESAVVKFPQFKLNPAASIQFQGHVFDVLAKDNIKKYKKGNIFHIDIQISSNLEDIKK
                     AFKIKTIGTAPNFK"
BASE COUNT          251 a          100 c           83 g          313 t
ORIGIN      
        1 ttttttattg ttaattgttt atttttctat tattagatat gaaaatcgca tttagataaa
       61 atagaaaaat atgaatatat tttaaatatt aagatgagag tcattaactt atgatagtag
      121 tcaatttgct tttcactaat tacaaaatat gtgatatagg aagtttagtt attgttctca
      181 taatgccatc ctgtttttag attatctagt aatttttttg ttatttaaaa ttaggagcag
      241 tgccaattgt tttaatttta aaggcttttt ttatatcttc taaattagaa gatatttgta
      301 tatcaatatg gaatatatta ccttttttgt atttttttat gttatcttta gctaaaacat
      361 caaatacatg tccttgaaat tgtatcgagg cagctggatt tagtttaaat tgaggaaact
      421 ttaccacagc tgattcaaaa cacttgtcac atttttttat atttttacct ttgtaaaaat
      481 attcgattga atattctatt tggcacgact cacttggcag tatatgtatg tcaatatttt
      541 tcatctgttt cataggtatt tcaacatcta aactattaaa aacatataat tccctgtaat
      601 tatttacatc taactctact aaatttatct ttggaacaat agatcctcca cccattccac
      661 cataataaaa aaaatcttgt tctctatcaa aatagcacat attaagctca gtttgtttat
      721 catcctcaat aattttataa atcaaac
//
LOCUS       DAXQKX010000192          730 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.211, whole genome shotgun sequence.
ACCESSION   DAXQKX010000192 DAXQKX010000000
VERSION     DAXQKX010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..730
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.211"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            175..461
                     /locus_tag="ACF3MF_002924"
                     /pseudo
     CDS             175..461
                     /locus_tag="ACF3MF_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368756.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          256 a          124 c           88 g          262 t
ORIGIN      
        1 cattattttg cagaaggacg agttatttac acaaaattat tgacgctccc tccaaattac
       61 ttcatcaaaa cattgatata atttttatta tatcagtatt tattcttgat acataaatga
      121 gaaaataaat actttaaatc tattgactac aagtagtcat taagtcttca taagatgtac
      181 aatatgacat taaaaaaata aaagcttacg accatccgtt aaatctgaca ctaaataatg
      241 gactgctttc ttttgtatta gcaggttacg ttgactatga atattcacca gattatttgg
      301 agaaacctct tcaacacgag aacaatgata ttaattttag atttgtctac gagtcaaaaa
      361 gtaaaacatg gttagttgat caattaagca cgataaacac aagcttccat gaattaccta
      421 aacctgaaaa tgaagttgag atggtcatta aaatcttcta aaaaagaagc gttgaagggg
      481 aaatattcct ttcaacgctc ttttttatat gcttagaaac ataaataaat tgtatacttt
      541 ctttttagcc cctattactt ttcacgaaaa atatcttttt ttcgacgcta gcgtttctct
      601 acttctaata ctgtacacag tttttgtatt attgaaaaat tactcattat ttagcattaa
      661 tccacatcgt tttatcaatc gaccttcata ctaaactact ttaaagtcat cttccttctc
      721 gtttttcatt
//
LOCUS       DAXQKX010000193          724 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.212, whole genome shotgun sequence.
ACCESSION   DAXQKX010000193 DAXQKX010000000
VERSION     DAXQKX010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..724
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.212"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..500)
                     /locus_tag="ACF3MF_002925"
     CDS             complement(<1..500)
                     /locus_tag="ACF3MF_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFE3928803.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVV"
BASE COUNT          228 a          136 c          107 g          253 t
ORIGIN      
        1 aagacgacga ttgcccagtc cgcaatgtac atcgcggatt tactatatac agaaatagaa
       61 ggtgggacat ctaaatagat gacgtcaaac tcatcaaata atggttctag cttttctttc
      121 atatatttga attgggataa tgaatcatta tattggtctt tgatccaatc atcatacatt
      181 tcaaaggaca tgtctgctgg aagtatatag aggttattga ttactttata gacagcctct
      241 ttaggtggaa gattgtttat caacacgtca gtcacagtat tttcgtaaac aatcggttca
      301 ccttctccgc ctccttcttc gttagtgaag ttcatatgcg ttaagttcat cacatcagaa
      361 gtatttcctt gcatatccaa gtcaattatc aaggttcttt ttccttcatt aactgctgat
      421 tcaaacccta acatttgcgc gcacgtactt ttacctacgc cacctttaaa attaccgatt
      481 acatatttct tcgctaccac gttcctacct cttttctttt agcaatattc atttgatact
      541 attataacat atttattttt agttactacc aaaaaaaaga tatatatgta ctaccttata
      601 attaataagg aaaaggtagt acatatataa ggaaaagctg aaatatattg atttatagct
      661 ttcctcaaag taatgacgtt atttaattta tcgagaagca gagaatactc gcgactttag
      721 tcat
//
LOCUS       DAXQKX010000194          720 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.213, whole genome shotgun sequence.
ACCESSION   DAXQKX010000194 DAXQKX010000000
VERSION     DAXQKX010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..720
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.213"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..576
                     /locus_tag="ACF3MF_002926"
     CDS             <1..576
                     /locus_tag="ACF3MF_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFE3928804.1"
                     /translation="MSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNV
                     YYVIQTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEES
                     FPKIIITPSATSCQFILNDYVFSFEGLVAGTDVVIDSDLMLCYEEQSDGDILDRSNKM
                     KTMQYPTLQVDINHFNCTGLSKIQIYRNGLR"
BASE COUNT          242 a          116 c          144 g          218 t
ORIGIN      
        1 atgtcgttta cattgcacta taactattta gaggatgtgg aagaccatca agcgttcaag
       61 caatcgtttt atatcatgcg tcattggtta aactatgcaa agaaattaga attctctgac
      121 gatcccaacg tctattacgt tatccagact atcgatattg gggatgcaga aaacgatatt
      181 gttgaatggg gagagttcga tgtaaatatt actgcgaaac cattcgcaag agttcaagaa
      241 gatgtaccta taaccgtaga taaaccacag tcatttaact tgctgaataa tagtttagaa
      301 gaaagttttc caaagattat catcactcct tcagctactt catgccagtt catcttaaat
      361 gattatgtgt ttagtttcga aggcttagta gcaggaactg atgtagtcat tgatagtgat
      421 ttgatgcttt gctacgaaga gcaatcggac ggagatattt tagatcggtc caacaaaatg
      481 aagaccatgc aatatccgac attgcaagtg gatatcaatc attttaattg cactggtttg
      541 agcaaaatac aaatttatcg taacgggtta aggtaggtga aatagatgat cgataattta
      601 ataactattt acgataaaaa tgacgcgaat aatttagctg aacatttata tgatacgcaa
      661 ggtttaggcg ctttgtcaga ctggttaaca gctactgtta gcaataaact aaacggagcc
//
LOCUS       DAXQKX010000195          708 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.214, whole genome shotgun sequence.
ACCESSION   DAXQKX010000195 DAXQKX010000000
VERSION     DAXQKX010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..708
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.214"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..>708)
                     /locus_tag="ACF3MF_002927"
     rRNA            complement(<1..>708)
                     /locus_tag="ACF3MF_002927"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          144 a          230 c          162 g          172 t
ORIGIN      
        1 tccggtttgt caccggcagt caccttagag tgcccaactg aatgctggca actaagatca
       61 agggttgcgc tcgttgcggg acttaaccca acatctcacg acacgagctg acgacaacca
      121 tgcaccacct gtcactctgc ccccgaaggg gacgtcctat ctctaggatt gtcagaggat
      181 gtcaagacct ggtaaggttc ttcgcgttgc ttcgaattaa accacatgct ccaccgcttg
      241 tgcgggcccc cgtcaattcc tttgagtttc agtcttgcga ccgtactccc caggcggagt
      301 gcttaatgcg ttagctgcag cactaagggg cggaaacccc ctaacactta gcactcatcg
      361 tttacggcgt ggactaccag ggtatctaat cctgttcgct ccccacgctt tcgctcctca
      421 gcgtcagtta cagaccagag agtcgccttc gccactggtg ttcctccaca tctctacgca
      481 tttcaccgct acacgtggaa ttccactctc ctcttctgca ctcaagttcc ccagtttcca
      541 atgaccctcc ccggttgagc cgggggcttt cacatcagac ttaagaaacc gcctgcgagc
      601 cctttacgcc caataattcc ggacaacgct tgccacctac gtattaccgc ggctgctggc
      661 acgtagttag ccgtggcttt ctggttaggt accgtcaagg tgccgccc
//
LOCUS       DAXQKX010000196          704 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.215, whole genome shotgun sequence.
ACCESSION   DAXQKX010000196 DAXQKX010000000
VERSION     DAXQKX010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..704
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.215"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
BASE COUNT          243 a           96 c          141 g          224 t
ORIGIN      
        1 gacggtatgt ggttaaaaaa gaaaaatagc taggagattt ttgagagatg actggtaaat
       61 ttaaaaatga tagaaatgga gagtatgtat gagtaataaa caatttttat ggtcttcttt
      121 tgcatttatt gttgttgata tttttttccg atattttaat aacgatatga tatttaactg
      181 gcaaagaatt ataatcgatt actgtatttt ttgtataata tattttttag tgaaaacatt
      241 tctaaaatac gcaaaaaaat aaaattgaag atgttattaa atcgcgatta tttacggaga
      301 tttatataaa taaaaacccc ctgacgaagt cgaagggggt ttttattttg gtttgaggtt
      361 tgcataccta ccgaaaaggt agggcagcaa atcgtcaaac aggtatcagc taattgcacc
      421 ataagggtgc gctgatactc ggctcaaaag agccgaaaga gccgtctgca agacccctcg
      481 gcgagcccac actttgcttg caaagtatag tgggttatac tttacatgga agtaattgcc
      541 ggaaatagtg aaaatgcctc acatttgtgc cacctaaaaa ggagcgattt acatatgagt
      601 tatgcagttt acgggccaag attgtttaag caaaataaga taagttaagg gatgcagttt
      661 atgcacccct taacttatct attaaataat ttatagctat tgaa
//
LOCUS       DAXQKX010000197          675 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.217, whole genome shotgun sequence.
ACCESSION   DAXQKX010000197 DAXQKX010000000
VERSION     DAXQKX010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..675
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.217"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..539)
                     /locus_tag="ACF3MF_002928"
     CDS             complement(<1..539)
                     /locus_tag="ACF3MF_002928"
                     /inference="COORDINATES: protein motif:HMM:NF016732.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFE3928805.1"
                     /translation="MGFWSNVRSFFRGAPEAKAAAKKDLAHWFIPRASIFGNYGEHAL
                     ADNETVFSAVSRLSNTMASLPIKAYKNYQPIESQASELLTYAPNHNMTSGEMIGLLET
                     HRAVYGNAYAIKRYGMRYEVVGLEVLDPSRVQPVIEETSRELWYEVFGDRGNYFVHNM
                     DMIHVKYTSVDGLKGISPL"
BASE COUNT          171 a          182 c          148 g          174 t
ORIGIN      
        1 tttaatggcg aaattccttt gagtccgtca accgacgtat acttaacgtg aatcatatcc
       61 atgttgtgaa cgaagtagtt gccgcgatca ccgaatacct cgtaccagag ctcgcgagac
      121 gtttcttcaa taaccggctg cactcgcgaa gggtctaaaa cctccaaccc gacgacttca
      181 taacgcattc cataccgctt tatcgcgtag gcattgccgt aaacagcccg atgagtctct
      241 aaaagtccga tcatttcacc ggaagtcatg ttatggttcg gcgcgtacgt taatagttcg
      301 gatgcctgcg actcgatcgg ctgatagttc ttgtacgcct tgatcggcag acttgccatc
      361 gtgtttgata accgcgatac agccgagaag acagtctcgt tatcagccaa cgcgtgttca
      421 ccatagtttc cgaaaatact agcgcgaggg ataaaccagt gcgcgagatc ctttttagcg
      481 gccgcctttg cttcaggtgc gcctctgaaa aagcttcgta cgttgctcca aaagcccaat
      541 ttcctcacct cctaaccgtt taatagatcg ttaatcgaga taaatccgac acttccacct
      601 gcaatcggct tcgtcatatc aagatatacc tgcgaatggg cgttaaggaa cgcagcaaag
      661 ccgtctatct ttcgg
//
LOCUS       DAXQKX010000198          671 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.218, whole genome shotgun sequence.
ACCESSION   DAXQKX010000198 DAXQKX010000000
VERSION     DAXQKX010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 671)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 671)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..671
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.218"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            155..349
                     /locus_tag="ACF3MF_002929"
     CDS             155..349
                     /locus_tag="ACF3MF_002929"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928806.1"
                     /translation="MHKREELENALSALEVELRSRESDLEDLREELQDVQNDIDDIEE
                     QIADIEDELDSLEDGEDSEC"
     gene            343..>671
                     /gene="nrdI"
                     /locus_tag="ACF3MF_002930"
     CDS             343..>671
                     /gene="nrdI"
                     /locus_tag="ACF3MF_002930"
                     /inference="COORDINATES: protein motif:HMM:NF019584.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HFE3928807.1"
                     /translation="MLIAYYSLTGNVRRFVAKTSLAAVEIKPGLMIAEPFVCVTGTYG
                     FGQVAGTVSDFLADNSDYLAGVAASGNRNWGDNFAKAADVIAEQYGVPVVGRFELAGT
                     EADVRQF"
BASE COUNT          175 a          149 c          213 g          134 t
ORIGIN      
        1 tgagacgttg gcttaacgaa aaaatgatcg aaagtgatac cgccatcagc ttccacgacc
       61 ggaaactgat cgaggagcgt atcgagcgag aacggacaca ggcgcgtctg gacgaagttg
      121 aggcggaaat tgagagacgg aaggggtaga tcggatgcat aaacgcgaag agctagaaaa
      181 tgcgttatca gcgttggaag tcgaactacg gtcgagggaa agcgatctcg aagacttacg
      241 tgaggagctg caggacgttc agaacgatat tgacgatatc gaagaacaaa tcgccgatat
      301 tgaggacgaa cttgactcgc tagaagacgg agaggattcc gaatgctgat cgcttattac
      361 tcgctgaccg gcaacgtccg ccgattcgtc gccaagacca gtctggccgc cgtcgaaatt
      421 aagccgggcc tgatgatcgc cgagccattc gtatgcgtga ccggtacgta tggcttcggt
      481 caggttgccg gcacagtttc ggatttcctt gcggataaca gcgactatct tgcgggcgtg
      541 gctgcgtcag ggaaccgtaa ctggggcgat aatttcgcaa aggcggccga tgtgattgcg
      601 gagcagtacg gcgtgccggt ggtcgggcgc tttgaattag cgggcacaga ggcagatgta
      661 cgacaattta t
//
LOCUS       DAXQKX010000199          621 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.221, whole genome shotgun sequence.
ACCESSION   DAXQKX010000199 DAXQKX010000000
VERSION     DAXQKX010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..621
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.221"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..>621
                     /gene="erm"
                     /locus_tag="ACF3MF_002931"
     CDS             <1..>621
                     /gene="erm"
                     /locus_tag="ACF3MF_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="23S ribosomal RNA methyltransferase Erm"
                     /protein_id="HFE3928808.1"
                     /translation="NDNIIEIGSGKGHFTFELAKRCNYVTAIEIDPKLCRITKNKLIE
                     YENFQVINKDILQFKFPKNKSYKIYGNIPYNISTDIIRKIVFESTATESYLIVEYGFA
                     KRLLNTNRSLALFLMTEVDISILSKIPREYFHPKPRVNSSLIVLKRHPSKISLKDRKQ
                     YENFVMKWVNKEYIKLFSKNQFYQALKYARIDDLNNISFEQFLSLF"
BASE COUNT          257 a           82 c           84 g          198 t
ORIGIN      
        1 aaatgataat attattgaga ttggttcagg gaaaggtcat ttcacgtttg aattagctaa
       61 aaggtgtaat tatgtaaccg ccattgaaat agatcctaaa ttatgtagga taactaaaaa
      121 caaacttatt gaatatgaga acttccaggt tatcaataaa gatattttac aatttaagtt
      181 tcctaaaaat aagtcatata agatatatgg aaatataccc tacaatataa gtacagatat
      241 aattcgaaaa attgtttttg aaagcacagc tacagaaagt tatttaatag tggaatatgg
      301 atttgctaaa aggttgctaa atacaaatcg ttcactagca ctatttttaa tgacagaagt
      361 tgatatatcc atattaagta aaatccctag agaatacttt catccaaaac ctagagttaa
      421 tagctcgtta attgtattaa aaagacaccc ttcaaaaata tcactcaaag atagaaaaca
      481 atatgaaaat tttgttatga aatgggttaa caaagaatac ataaaactat tttccaaaaa
      541 ccaattttat caagccttaa aatatgcaag aattgacgat ttaaacaata ttagctttga
      601 acaattcttg tctcttttca a
//
LOCUS       DAXQKX010000200          598 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.223, whole genome shotgun sequence.
ACCESSION   DAXQKX010000200 DAXQKX010000000
VERSION     DAXQKX010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..598
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.223"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..>598)
                     /locus_tag="ACF3MF_002932"
     CDS             complement(<1..>598)
                     /locus_tag="ACF3MF_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HFE3928809.1"
                     /translation="PEWLIDYAEKEGLIAELKPKHERQNFLVGDDRLDHAVAFLWKDP
                     QTGETVGASYQGTIVDFNRFGKRGTYKHIDKNPTPNHGFNLKIGDPKHLKFFESSIDL
                     LSYAALNREKLQDAWLVSMDGLKHHVISHYVEESISELRRKQTFPQSIEICVDNDRAG
                     HIFYEKEQMKGIVDPFTNKKIRCERGIPNDWQVPKEYKA"
BASE COUNT          161 a          136 c           91 g          210 t
ORIGIN      
        1 tagctttgta ttctttaggt acttgccaat catttggaat tcctcgctca caacggattt
       61 tcttattggt aaaaggatca acgattccct tcatctgttc tttttcataa aaaatatgtc
      121 ctgcacgatc attgtccaca catatttcaa tcgattgagg aaatgtttgt tttcgtctta
      181 attcagaaat cgactcttca acgtaatgac tgattacatg atgttttaac ccgtccatcg
      241 aaactaacca ggcatcttgt agtttctccc gattcaatgc agcgtaactt aacagatcaa
      301 tactactttc aaagaatttt aaatgcttcg gatcgcctat ttttaaatta aatccgtgat
      361 ttggcgtagg attcttgtca atgtgtttat acgttccccg tttaccgaaa cgattaaaat
      421 cgacgatcgt tccttgataa cttgccccta ctgtctctcc tgtctgtgga tctttccata
      481 aaaaagcaac cgcatgatct aaacggtcgt ctccaactaa aaaattttgc cgttcatgtt
      541 tcggctttag ttcagcaatc aacccttctt tttctgcata atcaatcagc cactctgg
//
LOCUS       DAXQKX010000201          592 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.224, whole genome shotgun sequence.
ACCESSION   DAXQKX010000201 DAXQKX010000000
VERSION     DAXQKX010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..592
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.224"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..>592
                     /locus_tag="ACF3MF_002933"
     CDS             <1..>592
                     /locus_tag="ACF3MF_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HFE3928810.1"
                     /translation="LMITEVSYETLQKKKTLVVDAVLSPTPRACRSCGSTVVDGNGKA
                     IIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQSYFVQPRHSIANHVR
                     YKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSKKILPRVLMVDEFRSH
                     ASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLG"
BASE COUNT          184 a          110 c          119 g          179 t
ORIGIN      
        1 ttgatgatta cagaggtctc ttacgagacc cttcagaaga aaaagacgtt ggtcgtcgat
       61 gctgttctct cgcctactcc tcgtgcttgt agaagttgtg gttctactgt ggtagatgga
      121 aacgggaaag caattatagt gaaaaatgga aaaaaggaaa cgattgtccg ttttgaacaa
      181 tacaatcata tgcctttggt tatgcgccta aaaaagcaac gctatacctg taaaaactgt
      241 cgcacccatt ggacggctca aagttatttt gtccaaccca gacattcaat cgcaaatcat
      301 gttagatata aaattgcttc tttactgact gaaaaagtat ctttatcttt tattgcgaaa
      361 agctgtcagg tatctttgac caccgttatt cgtacattga aagagtttaa aagctattta
      421 ccaaagcaat ctaagaagat cctccccaga gtattgatgg ttgacgaatt tcgttcgcat
      481 gcttccatag aagataagat gagctttatt tgcgcggatg gcgaaacagg aaaattaata
      541 gatgttttgc ctacgcgtaa attacctcga ttaacaagct atttcttagg tt
//
LOCUS       DAXQKX010000202          591 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.225, whole genome shotgun sequence.
ACCESSION   DAXQKX010000202 DAXQKX010000000
VERSION     DAXQKX010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..591
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.225"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(316..579)
                     /locus_tag="ACF3MF_002934"
     CDS             complement(316..579)
                     /locus_tag="ACF3MF_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HFE3928811.1"
                     /translation="MKKNLLLVLPILGFAGFFVGVPMLSANIGISSYAAKKVIDIINT
                     GSTVATIISIVAAVVGGGLITAGIVATAKSLIKKYGAKYAAAW"
BASE COUNT          224 a          103 c           78 g          186 t
ORIGIN      
        1 cttccttttt tgtatggatt ttttcattta cacaaaatat tttatactct cctgaatttt
       61 ttcatgttga aaacatcact aatcaaaggc aaattataat ttagaaatag aatgaaaaca
      121 ctaaatgaaa atagaacatt agaaaaaata gaatcaaaaa aacccaagac tagtgccgaa
      181 ataagggaaa caatcgaagc tacaaaaaat aatgatttcg ttgaacagga ccaatttatt
      241 tgtttccgat atttctcaaa aagaactttc tttgggaaag ttaaaggcga ctgtaaagtc
      301 gcctttagtc cttttttacc aagctgctgc atatttagct ccatattttt taattaatga
      361 tttggctgta gcaacaatac cagctgtaat taatccgcct ccaacaactg cagcaacaat
      421 agaaatgatt gtagcaaccg tgctaccagt attaattatg tcaataactt ttttagctgc
      481 ataagaagaa attccaatgt tagcacttag cattggtaca ccaacaaaga atcccgcaaa
      541 acctaaaatt ggtaaaacta ataataaatt ctttttcata ataattcctc t
//
LOCUS       DAXQKX010000203          590 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.226, whole genome shotgun sequence.
ACCESSION   DAXQKX010000203 DAXQKX010000000
VERSION     DAXQKX010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..590
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.226"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..191)
                     /locus_tag="ACF3MF_002935"
     CDS             complement(<1..191)
                     /locus_tag="ACF3MF_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase"
                     /protein_id="HFE3928812.1"
                     /translation="MGATITSKGRKKNLSSLLQYAANPSKKEKCVAVSGINCSDDSEE
                     ALQEMNLVRTKMNKSKDIA"
     gene            complement(176..>590)
                     /locus_tag="ACF3MF_002936"
     CDS             complement(176..>590)
                     /locus_tag="ACF3MF_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928813.1"
                     /translation="LTKQLNQIGNNLNQAVKALNIIAKYFREESEDKKEKSLHFSFDA
                     SRYNIFKDELANSIAKKLMISYPDDIFLESNRSAPSFFKLSEVEKEYFEYWIEKQTRP
                     GTKEEYSQKVDRNLIHSIQIIASLKDEVKQLWELL"
BASE COUNT          164 a          108 c           81 g          237 t
ORIGIN      
        1 tgtgctatat ctttagattt attcatcttg gtacgtacta aattcatttc ttgcagtgct
       61 tcctcactat catcactaca atttattcct gagactgcaa cacatttttc tttttttgaa
      121 ggattagctg catattgtaa tagcgaggat aaatttttct tgcgtccttt cgatgttata
      181 gtagctccca aagttgtttc acctcatctt ttaaacttgc aataatctga attgagtgaa
      241 ttaaattccg atcaactttt tgggaatact cttctttcgt acccggtcta gtttgctttt
      301 ctatccaata ttcgaaatat tctttttcta cttctgataa tttaaaaaaa gagggggcac
      361 tccgattgga ctccaaaaaa atgtcatctg gataactaat catcaacttt tttgctatgc
      421 tattcgcaag ttcatcttta aaaatgttgt aacggctagc atcaaaacta aaatgtaggc
      481 tcttttcttt tttatcttca gattcttctc taaaatattt agcaatgata tttaatgcct
      541 ttaccgcttg attcaaattg ttaccaattt gatttaactg tttggttaaa
//
LOCUS       DAXQKX010000204          564 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.227, whole genome shotgun sequence.
ACCESSION   DAXQKX010000204 DAXQKX010000000
VERSION     DAXQKX010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..564
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.227"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..>564
                     /locus_tag="ACF3MF_002937"
     CDS             <1..>564
                     /locus_tag="ACF3MF_002937"
                     /EC_number="5.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
                     /protein_id="HFE3928814.1"
                     /translation="QEGWKILFKQQTKEEKEDVQTLPLVIIGERAEVGVKSVEKETQP
                     PKAFTEGTLLTAMKTANKTVDDEEAIKILQEVEGIGTEATRASIIEALKQKEYIQVIK
                     NKLVVTEKGKLLCQAVESQHLLTSAEMTAKWETYLKKIGKREGNQENFITNIKKFIVH
                     LLEAVPNDIEKLNFSDYQEQKEKEAEKS"
BASE COUNT          238 a           77 c          121 g          128 t
ORIGIN      
        1 caagaagggt ggaaaattct tttcaaacaa caaaccaaag aagaaaaaga ggacgttcaa
       61 acgttaccac tcgttatcat tggcgaacgt gccgaagttg gtgttaagag tgttgaaaaa
      121 gaaacgcaac cgccaaaagc ttttacagag ggtacattat taactgctat gaaaacggcg
      181 aataaaacgg ttgatgatga agaagcaatc aagattttac aagaagttga ggggattgga
      241 acagaagcga caagagcaag tattattgaa gcgttaaaac aaaaagaata tatccaagtg
      301 attaagaata agcttgttgt aactgaaaaa ggaaaattat tgtgccaggc agttgaaagt
      361 cagcaccttt taacgagtgc tgaaatgacg gctaaatggg aaacgtattt aaaaaaaatc
      421 ggtaaaagag aaggcaatca agagaacttt attacgaata tcaaaaaatt cattgttcat
      481 ttactggaag ctgtacctaa cgatatagaa aaactaaatt tttctgatta ccaggaacag
      541 aaagaaaaag aagcagaaaa aagt
//
LOCUS       DAXQKX010000205          557 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.228, whole genome shotgun sequence.
ACCESSION   DAXQKX010000205 DAXQKX010000000
VERSION     DAXQKX010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..557
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.228"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..>557
                     /locus_tag="ACF3MF_002938"
     CDS             <1..>557
                     /locus_tag="ACF3MF_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS66 family transposase zinc-finger binding
                     domain-containing protein"
                     /protein_id="HFE3928815.1"
                     /translation="LTTEIQLLNEKVNYLTNKLFGRSKETLFEETNGQLNLFSDEEIS
                     VSVPEAAATIIPVKGHQRVVGTKADKIKHLPITEKEHLLPLEEQFCEHCGSQMKDIGR
                     TKVREEIRFHQAMLDCLTHYQHTYCCKSCEKEGLSSFKKAIVPKPLISNSLGSNSLVA
                     ETIRMKFGQKVPAYRQENYWKQTHG"
BASE COUNT          197 a          101 c          108 g          151 t
ORIGIN      
        1 atcttacaac tgaaatccaa ctattgaatg aaaaggtcaa ttatttaacc aacaaattat
       61 ttggacgctc taaagagact ctctttgagg aaacgaatgg gcaattgaat ctttttagtg
      121 atgaagaaat ttctgtaagt gttccagaag cagctgccac cattattcca gtaaaaggac
      181 atcaacgagt tgtaggaacg aaagcagaca aaatcaaaca cttacctata acagagaaag
      241 aacatctcct tcctttggaa gaacaatttt gtgaacattg cggttcacag atgaaagata
      301 tcggacggac aaaagtacga gaagaaattc gtttccatca ggctatgttg gattgtctca
      361 cccattatca acatacctat tgttgtaaaa gctgcgaaaa agaaggactt tcttctttta
      421 aaaaagcgat cgttcctaaa cctttgattt ctaatagctt aggttccaat agtttagtgg
      481 cggaaacgat ccggatgaaa tttggtcaga aagttcctgc ctatcggcaa gagaactatt
      541 ggaaacaaac acatggg
//
LOCUS       DAXQKX010000206          549 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.229, whole genome shotgun sequence.
ACCESSION   DAXQKX010000206 DAXQKX010000000
VERSION     DAXQKX010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..549
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.229"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            1..549
                     /locus_tag="ACF3MF_002939"
                     /pseudo
     CDS             1..549
                     /locus_tag="ACF3MF_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3-like element ISEfa8 family transposase"
BASE COUNT          201 a          112 c          116 g          120 t
ORIGIN      
        1 tacgccttct tctttcgata aatggatgaa gcaagcacaa tcaacgggct cattcaaaga
       61 aagagacaac ttaacaccag aacaagcaga attgatcgca ctaagaaaga aaaataagca
      121 actcgaaatg gagaatgata ttttaaagca agcggcgctg atattcggac gaaaagacaa
      181 gtaattgatg ccaacaagca taaatattcc atatcagcga tgtgcaaaat tctaaatatt
      241 tctcgtcaga cctactatta tcaagcgaaa ccgatcgaaa atgagtccga cttagaagag
      301 atcgttcagg aagagtttat tcgaaaccga aaggcttacg gtacccgaaa attgaagaag
      361 tgtttagcaa agcgtgggct tcaactcagt cggcgccgaa tcggtcgaat catgaaacgc
      421 cgcggattga catctaccta tacgatcgct cattttaaag ggcaacgaac agcttgtaat
      481 gaagcgaaaa cagcgaatgt attagatcgg acctttacac aagaacagcc attggaagcc
      541 atcgttacg
//
LOCUS       DAXQKX010000207          538 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.230, whole genome shotgun sequence.
ACCESSION   DAXQKX010000207 DAXQKX010000000
VERSION     DAXQKX010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..538
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.230"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..>538
                     /locus_tag="ACF3MF_002940"
     CDS             <1..>538
                     /locus_tag="ACF3MF_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HFE3928816.1"
                     /translation="FHIVKHMNQAFNELRIREMNELRKAGQKSQAEKLKKNWRFLLKN
                     RANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAYPFFHELVEAFRDKDP
                     DLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNGKIEAKNTHIKTMKRV
                     SYGFKSFENMRIRIFLIN"
BASE COUNT          190 a          109 c           97 g          142 t
ORIGIN      
        1 ggtttcatat tgtcaaacac atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga
       61 atgaacttcg taaagccgga cagaaaagcc aggcagaaaa actgaaaaag aactggcgct
      121 ttttgctaaa aaatcgtgca aacatcaacc attatgaata caaaacatgg aaaagtttcc
      181 gagcaccaaa atacccattt cttactgaag caatgatgat tgatcgattg cttgagtttt
      241 ctccgcccct aaaggaggcg tatccctttt ttcatgaatt agttgaagcc tttcgagaca
      301 aagaccctga cttatttttc tccttattgg cagaacttcc cgaaacgtta gatgacagct
      361 ttcgggaaaa gcttcaaaac cttctgacct atgaagaagg catcaccaac gcaatgatct
      421 atccttattc caatggaaaa atagaagcga agaataccca cataaagaca atgaaacgag
      481 tatcctacgg atttaaatca tttgagaaca tgagaattag aatctttttg atcaatca
//
LOCUS       DAXQKX010000208          534 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.231, whole genome shotgun sequence.
ACCESSION   DAXQKX010000208 DAXQKX010000000
VERSION     DAXQKX010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.231"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..89
                     /locus_tag="ACF3MF_002941"
     CDS             <1..89
                     /locus_tag="ACF3MF_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HFE3928817.1"
                     /translation="AKVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            259..519
                     /locus_tag="ACF3MF_002942"
                     /pseudo
     CDS             259..519
                     /locus_tag="ACF3MF_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
BASE COUNT          198 a           82 c          100 g          154 t
ORIGIN      
        1 acgccaaagt aaacaattta agtaccgtta cttatgagca agtattgtct atttttaata
       61 gttatctatt atttaacggg aggaaataat tctatgagtc gcttttgtaa atttggaaag
      121 ttacacgtta ctaaagggaa tgtagataaa ttattaggta tactactgac agcttccaag
      181 gagctaaaga ggtccctagc gcctacgggg aatttgtatc gataaggggt acaaattccc
      241 actaagcgct cgggacccct tgtaggaaaa tgtcctaagt gtggcaacaa tattgtatta
      301 aaaaaatcgt tttatggttg ttcaaattat cctgaatgta ccttcacttt agctgaacat
      361 tttagaaaga aaaaactcac caaaacaaat gtaaaagaat tactagaggg aaaagaaacc
      421 ctggtaaaag gaatcaaaac gaaagataga aagtcctaca atgccgttgt aaaaatcgga
      481 gaaaagggat atattgattt tatctctttt tcaaaataag cataaaagcc cttt
//
LOCUS       DAXQKX010000209          528 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.232, whole genome shotgun sequence.
ACCESSION   DAXQKX010000209 DAXQKX010000000
VERSION     DAXQKX010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.232"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(5..90)
                     /locus_tag="ACF3MF_002943"
     tRNA            complement(5..90)
                     /locus_tag="ACF3MF_002943"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(54..56),aa:Leu,seq:taa)
     gene            complement(107..178)
                     /locus_tag="ACF3MF_002944"
     tRNA            complement(107..178)
                     /locus_tag="ACF3MF_002944"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(144..146),aa:Gly,seq:gcc)
     gene            complement(190..262)
                     /locus_tag="ACF3MF_002945"
     tRNA            complement(190..262)
                     /locus_tag="ACF3MF_002945"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(227..229),aa:Thr,seq:tgt)
     gene            complement(280..361)
                     /locus_tag="ACF3MF_002946"
     tRNA            complement(280..361)
                     /locus_tag="ACF3MF_002946"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(325..327),aa:Leu,seq:tag)
     gene            complement(369..441)
                     /locus_tag="ACF3MF_002947"
     tRNA            complement(369..441)
                     /locus_tag="ACF3MF_002947"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(406..408),aa:Lys,seq:ttt)
     gene            complement(445..517)
                     /locus_tag="ACF3MF_002948"
     tRNA            complement(445..517)
                     /locus_tag="ACF3MF_002948"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(482..484),aa:Val,seq:tac)
BASE COUNT          135 a          152 c          128 g          113 t
ORIGIN      
        1 gaaatgccga ggaccggaat cgaaccggta cggtgatcac tcaccgcagg attttaagtc
       61 ctgtgcgtct gccagttccg ccaccccggc gcgattgctt tggcaaagcg gaaaacgggg
      121 ttcgaacccg cgacccccac cttggcaagg tggtgctcta ccactgagct atttccgcgt
      181 gtttaaagat gccggctaaa ggacttgaac cctcgaccct ctgattacaa atcagatgct
      241 ctaccaactg agctaagccg gcatgtaaaa cttaaattat gcgggtgaag ggacttgaac
      301 ccccacgccg taaggcgcta gatcctaaat ctagtgcgtc tgccaattcc gccacacccg
      361 caaaaatatg agccgtacag ggctcgaacc tgtgaccctc tgattaaaag tcagatgctc
      421 taccaactga gctaacggct catatggagg ttaacgggat cgaaccgctg accctctgct
      481 tgtaaggcag atgctctccc agctgagcta aacctccatg gataactt
//
LOCUS       DAXQKX010000210          518 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.233, whole genome shotgun sequence.
ACCESSION   DAXQKX010000210 DAXQKX010000000
VERSION     DAXQKX010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..518
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.233"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            413..>518
                     /locus_tag="ACF3MF_002949"
     rRNA            413..>518
                     /locus_tag="ACF3MF_002949"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          196 a           91 c          101 g          130 t
ORIGIN      
        1 aaatagttgt tgacatgtta gaaatgacat gataagataa ctgagtcgtt aaaaaaggac
       61 cgcttgcgaa gcttgattct atcgaaaaaa cttcaaaaaa gttcttgaca aataacaaac
      121 gacaagttat gataaatgag ttgctgtaag atttcgaaaa acgaaatcaa aaaaactttt
      181 aaaaaagagt tgacaattac ttgtctctct gatatgatat aaaagttgct gcggcagcca
      241 aaaacgaatc gggaaacact cctgatgaag tagacctttg aaaaatgaac aaagtaagac
      301 aaaccaaatg tgtagggcgt cttgattcaa ttcaagacaa caaacatttt taacaagcaa
      361 gcaatatgct agcaaacaaa ttgagcttaa caatcgcaag gttgttcgaa ctttttatga
      421 gagtttgatc ctggctcagg acgaacgctg gcggcgtgcc taatacatgc aagtcgaacg
      481 cttctttttc caccggagct tgctccaccg gaaaaaga
//
LOCUS       DAXQKX010000211          517 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.234, whole genome shotgun sequence.
ACCESSION   DAXQKX010000211 DAXQKX010000000
VERSION     DAXQKX010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..517
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.234"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(138..491)
                     /gene="tnpB"
                     /locus_tag="ACF3MF_002950"
     CDS             complement(138..491)
                     /gene="tnpB"
                     /locus_tag="ACF3MF_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HFE3928818.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
BASE COUNT          162 a          113 c           86 g          156 t
ORIGIN      
        1 ttgaagcaac tgaagcaacg tatctgtagt ttccaaaatt tttcaccacc ttgaatcgaa
       61 ctgattttgt tacagaatac cacaagaaac gcacaagaaa taggggttca acacattttt
      121 tgtgttaacc ccccagctta aaaaactcct ttttttcctg gcaaaatagc tcgaggttga
      181 tcgatactta atccttctaa caaccatcga acctgttggt tcgttaaggt tcgaacttcg
      241 tctttcgtcc gaggccattt taacttgccg ttttctatcc gcttataaca gagaagaaaa
      301 ccatcaccgt cccaatagag aagtttgaaa cggtcttgac ggttcccgca aaataaaaaa
      361 acggcatctt cgtaaagctc gagttgatac tcttgttgaa taagactggc aagaccatca
      421 attccttttc gcaaatctgt ttttccgcac acaatataaa tatgtttggt ttgaagtaaa
      481 tcataaagca ttggacaaca gttctttcaa aatagct
//
LOCUS       DAXQKX010000212          514 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.235, whole genome shotgun sequence.
ACCESSION   DAXQKX010000212 DAXQKX010000000
VERSION     DAXQKX010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..514
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.235"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(227..>514)
                     /locus_tag="ACF3MF_002951"
     CDS             complement(227..>514)
                     /locus_tag="ACF3MF_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFE3928819.1"
                     /translation="ETQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINLYYSNK
                     NYFKIPAAKTRMKKDVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
BASE COUNT          179 a           81 c           76 g          178 t
ORIGIN      
        1 atttgaagct attaaaaggc ataccatatt tttgaaaaaa agtgagaaaa aaggcttaca
       61 attggagtgg tagttaatta gtgacttatt tttgatttta tagcactgat actataaaat
      121 atagatatca tcatattaca caatcttaat actaacttaa aaaatatctc ctttcacaag
      181 tatggtgata aaattcgttc cgggctacct ttttaggtag cctactttaa tctttgtatc
      241 tttctggatc aacgaaagta tactttatat agtcataacg ccgatgatcg ctacgtgcgt
      301 ccggcacgtc agtcacgata tcaaacaaaa agtatacatc cttcttcatt ctagttttcg
      361 cagcaggaat tttgaaatag ttcttattag aatagtagag attgattaat aagctatctt
      421 cgattgctaa aaagaaaact tctgaattcc atactttata aaaatctttg ataaatctat
      481 tcgaagggtc aaatttaaac cataattgtg tctc
//
LOCUS       DAXQKX010000213          514 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.236, whole genome shotgun sequence.
ACCESSION   DAXQKX010000213 DAXQKX010000000
VERSION     DAXQKX010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..514
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.236"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..132)
                     /locus_tag="ACF3MF_002952"
     CDS             complement(<1..132)
                     /locus_tag="ACF3MF_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFE3928820.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          186 a           94 c           92 g          142 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactattag acaa
//
LOCUS       DAXQKX010000214          510 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.237, whole genome shotgun sequence.
ACCESSION   DAXQKX010000214 DAXQKX010000000
VERSION     DAXQKX010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..510
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.237"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
BASE COUNT          228 a           70 c           82 g          130 t
ORIGIN      
        1 gaattcctta ggcagctttt gctgtgtaga aaggaataaa taataacgaa agttcaaaag
       61 ctaatgccga ctattctaga cattaaagaa gacgaaaacg aacgataaag aaagaaaagt
      121 tatgaataat cgtttattga aaaaaacttg aaaaaataca aaaaattcgt tgaccaagct
      181 aaatttagtt ggtatattat tacttgtcca aaagacagaa gaaaatattt attcaaaaac
      241 ataacaaaaa agttattgac atgttactaa cgacatgata agataactga gtcgttaaaa
      301 aagaaccact tgcgaagctt gattctatcg aaaaaaactt caaaaaagtt cttgacaaat
      361 aacaaacgat aagttatgat aaatgagttg ccgaaagatt tcgaaaaacg aaatcgaaaa
      421 aaacttttaa aaaagagttg acaatcgctt gtctctctga tatgatataa aagttgctac
      481 ggcagccaaa aatgaatcgg gaaacactct
//
LOCUS       DAXQKX010000215          505 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.238, whole genome shotgun sequence.
ACCESSION   DAXQKX010000215 DAXQKX010000000
VERSION     DAXQKX010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..505
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.238"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..>505
                     /locus_tag="ACF3MF_002953"
     CDS             <1..>505
                     /locus_tag="ACF3MF_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928821.1"
                     /translation="YRGTGMRDSNNPKDYVWDLAPEYVEDNLATDIKISEITGKANNY
                     TDGKVSKINSQLTASINEVDTTAKGAQTKANANATAIDELDNKIDERINDTATTAFYG
                     AQGEVSNKTKVAEYGVGTGYTTTAVGETHFERQSNGYVKCLKAGKYSISAQIRVQLGG
                     KYASWLYT"
BASE COUNT          180 a           82 c          112 g          131 t
ORIGIN      
        1 tatcgtggta ctggtatgcg tgattcaaac aatccaaaag attatgtttg ggatctagca
       61 ccagaatatg tcgaagataa tttggccaca gatattaaaa tttctgaaat tactggtaaa
      121 gcaaacaatt ataccgatgg gaaagtatcg aagattaatt cgcagttgac tgcttcaatt
      181 aatgaagtag acaccacagc taagggtgct caaacaaaag cgaatgctaa tgcgactgct
      241 atagatgaat tagacaataa gatcgatgaa cgcattaatg atacagctac taccgcattt
      301 tatggcgcac aaggtgaagt ctctaacaaa acgaaagtag cggagtatgg agtaggaaca
      361 gggtatacta ctacagctgt aggagaaaca catttcgaac gtcaatctaa cggatacgtt
      421 aaatgcttaa aagctggtaa gtattcaatt agtgcgcaaa tacgtgtgca attgggcggg
      481 aaatatgctt catggttata tactg
//
LOCUS       DAXQKX010000216          500 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.239, whole genome shotgun sequence.
ACCESSION   DAXQKX010000216 DAXQKX010000000
VERSION     DAXQKX010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..500
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.239"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..>500
                     /locus_tag="ACF3MF_002954"
     CDS             <1..>500
                     /locus_tag="ACF3MF_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein"
                     /protein_id="HFE3928822.1"
                     /translation="SLYPVYHGSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFK
                     IEYSEERQRLAYVRLYGGILHLRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEI
                     VILQNEFLKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDS
                     DPLLQY"
BASE COUNT          179 a           82 c          100 g          139 t
ORIGIN      
        1 tccttgtacc ctgtttatca tggaagcgca aaaagcaaca tagggattga gcagcttata
       61 gaagtgataa cgaataaatt ttattcatca acatacagaa agaagtctga actttgcgga
      121 aatgtcttca aaattgaata ttcggaagaa agacaacgtc ttgcatatgt acgcctttat
      181 ggcggaatcc tgcatttgcg ggattcggtt agaatatcgg aaaaggaaaa aataaaaatt
      241 acagaaatgt atacttcaat aaatggtgaa ttatgtaaaa ttgataaggc ttattccggg
      301 gaaattgtta ttttgcaaaa tgagtttttg aagctaaata gtgttcttgg agatacaaag
      361 ctattgccac agagagagag aattgaaaat ccgctccctc tgctgcaaac aactgttgaa
      421 ccgagcaaac ctcaacaaag ggaaatgtta cttgatgcac ttttagaaat ctccgacagt
      481 gacccgcttc tacaatatta
//
LOCUS       DAXQKX010000217          463 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.240, whole genome shotgun sequence.
ACCESSION   DAXQKX010000217 DAXQKX010000000
VERSION     DAXQKX010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..463
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.240"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..>463)
                     /locus_tag="ACF3MF_002955"
     CDS             complement(<1..>463)
                     /locus_tag="ACF3MF_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="relaxase"
                     /protein_id="HFE3928823.1"
                     /translation="GELITLGRDKQSRKEKSQYVERTFSARKLGKRYSFESVSEQLEK
                     NLEESHIKNFFNMEREQVMSLISGVNYKTGELNVPFVELDSIAQKQFSDREGDEKFIK
                     YDDFLREVDKHFVNTMSLEDDQEYTIKLHTDVNPQTLRSAKSKTISIKKTDQ"
BASE COUNT          132 a           90 c           56 g          185 t
ORIGIN      
        1 ctgatcagtc tttttaatag aaattgtttt acttttcgca ctacgtaaag tttgaggatt
       61 cacatccgta tgaagtttaa tcgtgtattc ttgatcatct tctaaagaca ttgtatttac
      121 aaaatgcttg tctacctctc gcaagaagtc atcatattta atgaattttt catcgccttc
      181 acggtcgcta aattgctttt gtgcgatgga atctaattcc acaaacggta catttaactc
      241 accagttttg taatttactc cactaattag cgacataact tgctctcttt ccatattaaa
      301 aaaatttttt atatgtgatt cttctaaatt cttttcaagt tgttcagaaa cagattcaaa
      361 tgaatatctt ttccctaact ttcttgcact aaaagtacgt tcgacatact gacttttttc
      421 ttttctagat tgtttatctc ttcctaaagt aattaactca cct
//
LOCUS       DAXQKX010000218          460 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.241, whole genome shotgun sequence.
ACCESSION   DAXQKX010000218 DAXQKX010000000
VERSION     DAXQKX010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.241"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..>460)
                     /locus_tag="ACF3MF_002956"
     CDS             complement(<1..>460)
                     /locus_tag="ACF3MF_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928824.1"
                     /translation="INGTNADLIVDGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEV
                     KAEPIFNDIRKSVLNKYDSGTEKITATQAWQNAKVLAKPAIPSQFSFSSLVDTLANVK
                     IEKANFLEFFGGKEGSILDRFHGEFLKDNNTLRHEKSLGTDHKIKAIYTK"
BASE COUNT          129 a           91 c           68 g          172 t
ORIGIN      
        1 tttttagtat aaatcgcttt gattttatga tccgtaccta gacttttttc atgacgtaat
       61 gtgttattat cttttagaaa ctcaccatga aatcgatcta gaatagatcc ctcttttcca
      121 ccaaagaatt ctaaaaaatt cgccttttct atcttcacat tagcaagcgt atctactaat
      181 gacgagaaag aaaactgcga agggatagct ggtttcgcta aaacttttgc gttttgccat
      241 gcctgagtag cagtgatctt ttctgttccg ctgtcatatt tattcaacac cgattttctt
      301 atatcattga aaataggttc agcttttact tctatcgtat tgcctattac agaagttttt
      361 gcataataaa tccgtagacg ctgttttgct cgattttcat ctacataaca ctgaataata
      421 cgtccgtcta caatcaaatc tgcattagtt ccgtttattg
//
LOCUS       DAXQKX010000219          444 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.243, whole genome shotgun sequence.
ACCESSION   DAXQKX010000219 DAXQKX010000000
VERSION     DAXQKX010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.243"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..>444
                     /locus_tag="ACF3MF_002957"
     CDS             <1..>444
                     /locus_tag="ACF3MF_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HFE3928825.1"
                     /translation="INVSHTTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIK
                     GKWHYLYRAIDADGLTLDIWLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSA
                     FKKLKEYGFYQGTEHRTIKYLNNLIEQDHRPVKRRNKFYRSLRTAS"
BASE COUNT          161 a           79 c           83 g          121 t
ORIGIN      
        1 cattaacgtt tctcatacga cgatttatcg ttgggtgcaa gaatatggca aactactcta
       61 tcaaatttgg aaaaagaaaa ataaaaaatc cttttattca tggaaaatgg atgaaacgta
      121 catcaaaatt aaaggaaaat ggcattattt gtatcgagcc atcgatgcag atggtttaac
      181 cttggatatt tggttacgta aaaaacggga cacacaagca gcctatgctt ttcttaagcg
      241 gttagtgaag cagtttgatg aaccgaaggt tgtagtcaca gataaagccc cctctattac
      301 aagtgccttt aagaaactaa aagaatacgg cttttatcaa gggacagaac atcgtaccat
      361 taaatacctg aataatttga ttgaacaaga ccatcgtcca gtaaagagac gcaataaatt
      421 ctatcgaagt ttacgcactg cctc
//
LOCUS       DAXQKX010000220          420 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.244, whole genome shotgun sequence.
ACCESSION   DAXQKX010000220 DAXQKX010000000
VERSION     DAXQKX010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.244"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..>420
                     /locus_tag="ACF3MF_002958"
     CDS             <1..>420
                     /locus_tag="ACF3MF_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928826.1"
                     /translation="LDLPINSNSITQEWKEFSITGTTPTFSPQAYHPWIQFRAQDGIL
                     GEIEMSYDIKIEEGSTATPFQPNLLAEPYNMCREYPNENIADHTVKFPIESGDHQIYQ
                     GYTEEELMIGQTYTITLKGTKPASQTFVAYNHWTARLG"
BASE COUNT          152 a           89 c           75 g          104 t
ORIGIN      
        1 ttagacttac ctattaacag taattcgata actcaggaat ggaaagagtt tagtattact
       61 ggaactactc caacatttag cccacaagca taccatcctt ggatacaatt tagggctcaa
      121 gatgggatac ttggggaaat agaaatgagc tatgacatca aaatcgaaga aggctcaaca
      181 gctacaccat tccaacctaa cttattagca gaaccttaca acatgtgtcg cgaatatcct
      241 aacgaaaata ttgccgatca tacagttaag ttcccaatcg aatctggcga ccaccaaata
      301 tatcaaggtt acacagaaga agagcttatg ataggtcaaa cgtatactat cacgcttaaa
      361 ggaacaaaac ccgcaagtca aacctttgta gcgtataatc attggactgc tcgtttagga
//
LOCUS       DAXQKX010000221          397 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.245, whole genome shotgun sequence.
ACCESSION   DAXQKX010000221 DAXQKX010000000
VERSION     DAXQKX010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..397
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.245"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..168
                     /locus_tag="ACF3MF_002959"
     CDS             <1..168
                     /locus_tag="ACF3MF_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFE3928827.1"
                     /translation="PLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGL
                     YRADYGDKSQF"
     gene            272..>397
                     /locus_tag="ACF3MF_002960"
     CDS             272..>397
                     /locus_tag="ACF3MF_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HFE3928828.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFS"
BASE COUNT          164 a           37 c           71 g          125 t
ORIGIN      
        1 cctttaataa atagattggt gaattatcta tattttactg cttatactaa taaaataaga
       61 ttcactgaat atcaagagga attaataaga aatttgagtg aaattggaag aactgctgga
      121 ataaatggtt tatatcgagc agattatgga gataaatctc aattttaatg atacttataa
      181 tattaaatat gtctcaaaat tttttgatta gaaaaatagg tatattgaat cagtgacata
      241 aaagtattta tagtttgtag ggggaatcgt aatggaagaa aaaaatagac taaatgctaa
      301 acaatgttca gatcaagagc ttaaaaaaat taaaggaggt gctggaacaa aacctcaagg
      361 aaaaccggca tcaaatttag tggaatgtgt tttttca
//
LOCUS       DAXQKX010000222          394 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.246, whole genome shotgun sequence.
ACCESSION   DAXQKX010000222 DAXQKX010000000
VERSION     DAXQKX010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 394)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 394)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..394
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.246"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..>394
                     /locus_tag="ACF3MF_002961"
     rRNA            <1..>394
                     /locus_tag="ACF3MF_002961"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT           96 a           95 c          130 g           73 t
ORIGIN      
        1 agtttgatcc tggctcagga cgaacgctgg cggcgtgcct aatacatgca agtcgagcgg
       61 acagatggga gcttgctccc tgatgttagc ggcggacggg tgagtaacac gtgggtaacc
      121 tgcctgtaag actgggataa ctccgggaaa ccggggctaa taccggatgg ttgtttgaac
      181 cgcatggttc agacataaaa ggtggcttcg gctaccactt acagatggac ccgcggcgca
      241 ttagctagtt ggtgaggtaa cggctcacca aggcgacgat gcgtagccga cctgagaggg
      301 tgatcggcca cactgggact gagacacggc ccagactcct acgggaggca gcagtaggga
      361 atcttccgca atggacgaaa gtctgacgga gcaa
//
LOCUS       DAXQKX010000223          385 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.247, whole genome shotgun sequence.
ACCESSION   DAXQKX010000223 DAXQKX010000000
VERSION     DAXQKX010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..385
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.247"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
BASE COUNT          154 a           53 c           44 g          134 t
ORIGIN      
        1 taaaacctat acttgcattt ctactcctat caaaaatcca tatattcaga agtaataata
       61 tcgctactat taagataaaa ttactataaa aaagcaaaat attacctcct aattaaatat
      121 taaataccga aaaaattatg tttagataat accatagtta agtttttcct tgtgatgttt
      181 ttcgtaaaaa gatattttag cagcattatc gttacagtgc atagttacca tcggcgttat
      241 gactatataa agtatacttt cgttgatcca gaaaggtata tagattaaaa taagttacct
      301 aaaaaggaca aatacaaatt ttattatctt attcacagta agaagataat tttaagattg
      361 cgaaatacga tactatttgt aatct
//
LOCUS       DAXQKX010000224          381 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.248, whole genome shotgun sequence.
ACCESSION   DAXQKX010000224 DAXQKX010000000
VERSION     DAXQKX010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.248"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
BASE COUNT          164 a           50 c           38 g          129 t
ORIGIN      
        1 aaacaaaaat aaataaagtc ggatttttct gataattcaa cgcaaaaaaa cgaacaattt
       61 ttcaataaat cagtcttcta aaatagataa cctaaaaaaa acgaacaaac aaataaaatg
      121 actgtccttc attcactaaa catattttta ttttttatat tgttaaaaat tcacaattat
      181 tttttaatag aattatctgt tttccaaatt ttataacata aaaaaccttt tttaacggca
      241 tttatatgct ttttcagaaa ttaactgatg atttcaaaaa gaaaacatgt cataatattt
      301 cccatattgt gcaaaaaaat acaaggtgga ggctctacta tgattgaaga atatattgag
      361 aaaaatattt taagacagct g
//
LOCUS       DAXQKX010000225          372 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.249, whole genome shotgun sequence.
ACCESSION   DAXQKX010000225 DAXQKX010000000
VERSION     DAXQKX010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..372
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.249"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            221..322
                     /locus_tag="ACF3MF_002962"
                     /pseudo
     CDS             221..322
                     /locus_tag="ACF3MF_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
BASE COUNT          126 a           39 c           80 g          127 t
ORIGIN      
        1 cgtgaaatag agaggattta tttttctggt tacgtgatta aaaaatccaa aaaatgagca
       61 taggaacggt tatgatttta gggtgtgttt taatgagata ttgtaatttc attaacaagt
      121 gtatgataat ctgttgttga gttagtaggt tctgttgcaa agttttccaa aaaatctatt
      181 ttagtgtaaa attgagaaaa aagacagaga ggacagagta atgaatcatt ttaaaggcaa
      241 acaattcaaa aaagacgtca ttattgtcgc tgttggttac tacctgcgtt acaatctaag
      301 ctatcgtgaa gttcaggaat tgtgatatga tcgtggaata aatgtttgtc atactacgat
      361 ttatcgttgg gt
//
LOCUS       DAXQKX010000226          359 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.250, whole genome shotgun sequence.
ACCESSION   DAXQKX010000226 DAXQKX010000000
VERSION     DAXQKX010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..359
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.250"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..>359)
                     /locus_tag="ACF3MF_002963"
     CDS             complement(<1..>359)
                     /locus_tag="ACF3MF_002963"
                     /EC_number="5.6.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
                     /protein_id="HFE3928829.1"
                     /translation="QGLYEAKLLSYPRTDTPFITENEFAYLKANFGKYSGFLGLDLEM
                     VQTEPRKRYVDGSKVQEHHAIIPTKQVPTESALAKMDDLQRKIYALVVKTTVAMFLPD
                     YLYEETKIQTKVADLLF"
BASE COUNT           98 a           67 c           63 g          131 t
ORIGIN      
        1 tgaaacagca aatcagctac tttcgtttgt atcttggttt cttcatacaa gtaatcaggt
       61 aaaaacatgg caacggtcgt tttaacgact aaagcatata tttttcgttg taaatcgtcc
      121 atttttgcta atgcagattc ggtaggtact tgttttgttg ggataatggc gtggtgttcc
      181 tgtaccttac taccgtccac ataacgcttt ctaggctctg tttgaaccat ttcgagatca
      241 agtcctaaaa aaccgctata tttgccaaaa tttgctttta aataagcaaa ttcgttctct
      301 gtaataaatg gtgtatctgt tcttggataa ctcaataatt ttgcttcata cagtccttg
//
LOCUS       DAXQKX010000227          356 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.251, whole genome shotgun sequence.
ACCESSION   DAXQKX010000227 DAXQKX010000000
VERSION     DAXQKX010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 356)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 356)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..356
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.251"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            205..306
                     /locus_tag="ACF3MF_002964"
                     /pseudo
     CDS             205..306
                     /locus_tag="ACF3MF_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010868911.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
BASE COUNT          123 a           37 c           77 g          119 t
ORIGIN      
        1 cgtgaaatag aggggattta tttttctggt tacgtgatta aaaaatccaa aaaatgagca
       61 taggaacggt tatgatttta gggtgtgttt taatgagata ttgtgatttc attaacaagt
      121 gtatgataat cggttctgtt gcaaagtttt ccaaaaaatc tattttagtg taaaattgag
      181 aaaaaaaaca gagaggacag agtaatgaat cattttaaag gcaaacaatt caaaaaagac
      241 gtcattattg tcgctgttgg ttactagctg agttacaatc taagctatcg tgaagttcag
      301 gaattgtgat atgatcgtgg aataaatgtt tgtcatacta cgatttatcg ttgggt
//
LOCUS       DAXQKX010000228          347 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.252, whole genome shotgun sequence.
ACCESSION   DAXQKX010000228 DAXQKX010000000
VERSION     DAXQKX010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.252"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..240
                     /locus_tag="ACF3MF_002965"
     CDS             <1..240
                     /locus_tag="ACF3MF_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase core domain-containing protein"
                     /protein_id="HFE3928830.1"
                     /translation="DNAVAESTYKSLKVEFVYQYTFETLQQLDLELFDYVNWWNHLRL
                     HGTLGYETPVGYRNQRLAQRILDNELGCANASEAV"
BASE COUNT          101 a           71 c           80 g           95 t
ORIGIN      
        1 gataatgccg tagctgaatc aacttataag tcgttgaaag tagaatttgt ctatcaatac
       61 acatttgaaa ccttacaaca attggatttg gagttatttg actatgtcaa ttggtggaac
      121 caccttcggt tgcacggtac acttggctac gagacaccgg ttggttaccg taaccagaga
      181 ttggcgcagc gaatccttga taatgagctc ggatgtgcta acgctagcga ggcagtctaa
      241 ctttaactgt tagctcctgc cgaagatcgt cacatccgag gaggctcatt gtcaaggaca
      301 atcggaatag catacggaaa gaagttctgc accttataaa atttgtc
//
LOCUS       DAXQKX010000229          341 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.253, whole genome shotgun sequence.
ACCESSION   DAXQKX010000229 DAXQKX010000000
VERSION     DAXQKX010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.253"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            1..341
                     /locus_tag="ACF3MF_002966"
                     /pseudo
     CDS             1..341
                     /locus_tag="ACF3MF_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT          134 a           59 c           63 g           85 t
ORIGIN      
        1 ttcacaagaa ttcaagcaac aaatcgtcaa tctttactta gctggaaagc cacgtgtaga
       61 aatcattcga gaatatgaac taacggcttc agcatttgac aaatgggtaa agcaatctaa
      121 aacgagtggt tcattcaaag aaaaagataa tcttacgcct gaacaaaaag aattgttaga
      181 actacgtaaa agaaaccagc aattagaaat ggaaaatgat attttaaagc aagcagcgct
      241 gatattcgga cgaagagaca agtaatcgat gcgaataagc atctttaccc tatatcagcg
      301 atgtgcagaa tattaggtct atcacgtcag tcctattatt a
//
LOCUS       DAXQKX010000230          333 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.254, whole genome shotgun sequence.
ACCESSION   DAXQKX010000230 DAXQKX010000000
VERSION     DAXQKX010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..333
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.254"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..321)
                     /locus_tag="ACF3MF_002967"
     CDS             complement(<1..321)
                     /locus_tag="ACF3MF_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HFE3928831.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHL"
BASE COUNT           95 a           54 c           61 g          123 t
ORIGIN      
        1 taaatggata atagtggttt ccaatgtatc gtttgttctt ttgtaggctg gtaaagtttg
       61 ttgtttaaac tcaccattac gatctctagg tatttccaat gttaattcac catattcggt
      121 tttgattgat cgaaagtaag aaccgtttct cgaattacct gaattaaaac cagtgcgatc
      181 atatttttcg taatctaaaa aagccgttaa ttcagtccgt aggagtgtgt ttatcgcttt
      241 ttctaagtgc gaacggaata attcatttaa atcgccttta gtgactagag tttgcacaat
      301 ttctgtagta aaatcattca tagggaagtc ctc
//
LOCUS       DAXQKX010000231          332 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.255, whole genome shotgun sequence.
ACCESSION   DAXQKX010000231 DAXQKX010000000
VERSION     DAXQKX010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..332
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.255"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..>332
                     /locus_tag="ACF3MF_002968"
     CDS             <1..>332
                     /locus_tag="ACF3MF_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928832.1"
                     /translation="IILSFLGKVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAE
                     YTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQ
                     GLYGWNVT"
BASE COUNT          103 a           53 c           78 g           98 t
ORIGIN      
        1 attatacttt ctttcttagg gaaagtacaa atggaagtga ttagtgcact gttgcaagaa
       61 aagtatcatg tggagataga actaaaagag cctacagtca tttatatgga gagaccgtta
      121 aaaaatgcag aatataccat tcacatcgaa gtgccgccaa atcctttctg ggcttccatt
      181 ggtttatctg tatcaccgct tccgttggga agtggaatgc agtatgagag ctcggtttct
      241 cttggatact taaatcaatc atttcaaaat gcagttatgg aagggatacg ctatggttgc
      301 gaacaaggat tatatggttg gaatgtgacg ga
//
LOCUS       DAXQKX010000232          319 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.256, whole genome shotgun sequence.
ACCESSION   DAXQKX010000232 DAXQKX010000000
VERSION     DAXQKX010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 319)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 319)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..319
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.256"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            76..>319
                     /locus_tag="ACF3MF_002969"
     CDS             76..>319
                     /locus_tag="ACF3MF_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3928833.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIK"
BASE COUNT          134 a           51 c           54 g           80 t
ORIGIN      
        1 agaaaaataa aaaggcattt atggtacact caaattgtat ttccgacgaa agaaaacaaa
       61 ggagtgtaac cataaatgac ctacaaacat cttaccatag acgaactgac aatgatagaa
      121 tcatattatc ttcaacataa taagccggtt gaaatcgcta accgaatggg acgtgctata
      181 caaactattt ataatgtagt caataagttc aagcaaggca agactgctct tgattattgg
      241 caccagtata aagaaaataa gaaaaaatgt ggtagaaaag tcattcaatt acctgctcat
      301 gaagtagatt acattaaag
//
LOCUS       DAXQKX010000233          314 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.257, whole genome shotgun sequence.
ACCESSION   DAXQKX010000233 DAXQKX010000000
VERSION     DAXQKX010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..314
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.257"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..>314
                     /locus_tag="ACF3MF_002970"
     rRNA            <1..>314
                     /locus_tag="ACF3MF_002970"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT           99 a           69 c           89 g           57 t
ORIGIN      
        1 gaaataatag taccgaagtt cctgatgtca cactgccgag aaaagcttct agtgagaaaa
       61 cagcggcccg taccgcaaac cgacacaggt agtcgaggag agaatcctaa ggtgagcgag
      121 agaactctcg ttaaggaact cggcaaaatg accccgtaac ttcgggagaa ggggtgctga
      181 tcatacgatc agccgcagtg aataggccca agcgactgtt tatcaaaaac acaggtctct
      241 gcaaaatcgt aagatgaagt ataggggctg acgcctgccc ggtgctggaa ggttaagagg
      301 agtgcttagc gcaa
//
LOCUS       DAXQKX010000234          313 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.258, whole genome shotgun sequence.
ACCESSION   DAXQKX010000234 DAXQKX010000000
VERSION     DAXQKX010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..313
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.258"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(109..>313)
                     /locus_tag="ACF3MF_002971"
     CDS             complement(109..>313)
                     /locus_tag="ACF3MF_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="integrase core domain-containing protein"
                     /protein_id="HFE3928834.1"
                     /translation="KVEFVHQYQFETLAQLRLELFDYVHWWNYLRLHGTLAYETPIQI
                     RQQRLAKRILDNERGSDTSGEAA"
BASE COUNT           80 a           73 c           67 g           93 t
ORIGIN      
        1 gacaaaaatt ataaggtgtt gtgaatgctg cggtgttatg gctccgattg cccttgacaa
       61 tgagcatcct cggatctgat tttctccggc agaagcacaa tcattcaatt acgctgcctc
      121 tccagaggta tcagatccgc gctcattatc aaggattcgc ttcgccaatc tctgttgtcg
      181 aatttggatc ggtgtttcat acgccaacgt gccatgtaag cgtagatagt tccaccaatg
      241 cacataatca aacaattcta gacgtagctg tgccagtgtc tcaaattggt attgatgcac
      301 gaattctact ttg
//
LOCUS       DAXQKX010000235          313 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.259, whole genome shotgun sequence.
ACCESSION   DAXQKX010000235 DAXQKX010000000
VERSION     DAXQKX010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..313
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.259"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..>313
                     /locus_tag="ACF3MF_002972"
     CDS             <1..>313
                     /locus_tag="ACF3MF_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element ISS1D family transposase"
                     /protein_id="HFE3928835.1"
                     /translation="YYLWKKKNRQSFYSWKMDETYIKIKGRWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLHKQFGEPKAIVTDKAPSLGSAFRKLQSVGLYTKTEHRTVK
                     YL"
BASE COUNT          103 a           58 c           66 g           86 t
ORIGIN      
        1 tattatcttt ggaagaagaa aaatagacaa tccttctatt catggaaaat ggacgaaacc
       61 tatatcaaaa ttaagggacg ttggcattat ctttatcgtg caattgatgc ggacggctta
      121 accttagata tctggttacg aaagaaacgg gatacgcaag cagcctatgc tttcttaaaa
      181 cgactccata aacagtttgg tgagccgaaa gcaattgtga ccgataaagc accttctctt
      241 ggctccgcct ttagaaagtt acagagtgtg ggtttatata ctaagacaga gcaccgaact
      301 gtgaagtatc tta
//
LOCUS       DAXQKX010000236          309 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.260, whole genome shotgun sequence.
ACCESSION   DAXQKX010000236 DAXQKX010000000
VERSION     DAXQKX010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.260"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..>309
                     /locus_tag="ACF3MF_002973"
     rRNA            <1..>309
                     /locus_tag="ACF3MF_002973"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT           94 a           68 c           91 g           56 t
ORIGIN      
        1 cgaatgggga aacccaccac tcgtaatgga gtggtatcca tatctgaata cataggatat
       61 gagaaggcag acccggggaa ctgaaacatc taagtacccg gaggaagaga aagcaaatgc
      121 gattccctga gtagcggcga gcgaaacggg accagcccaa accaagaggc ttgcctcttg
      181 gggttgtagg acactctgta cggagttaca aaggaacgag gtagatgaag aggtctggaa
      241 aggcccgcca taggaggtaa cagccctgta gtcaaaactt cgttctctcc tgagtggatc
      301 ctgagtacg
//
LOCUS       DAXQKX010000237          304 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.261, whole genome shotgun sequence.
ACCESSION   DAXQKX010000237 DAXQKX010000000
VERSION     DAXQKX010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.261"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
BASE COUNT           99 a           68 c           29 g          108 t
ORIGIN      
        1 cttatttatt actagtgttt caagcggatc aactttattt tcttcagcca ctcttccaat
       61 ttcctcactt tcattttcaa aaatcacaaa aatgatatta acttaaaagc cactaacaaa
      121 ataagactta caaagtaaag ggtaatccaa caaaataacc attcgctcta cgtactacga
      181 tttggtagtc ctgcctttca atcggtaatt cataatagta atttactgtt tcttctttgc
      241 cactttcaat atactctgga ttatccaata tcatagcata ctcataaagt tcttcaccat
      301 cctt
//
LOCUS       DAXQKX010000238          302 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.262, whole genome shotgun sequence.
ACCESSION   DAXQKX010000238 DAXQKX010000000
VERSION     DAXQKX010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..302
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.262"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..>302
                     /locus_tag="ACF3MF_002974"
     CDS             <1..>302
                     /locus_tag="ACF3MF_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HFE3928836.1"
                     /translation="EDIFAYILEQAVKAGFVTEDNLYLDSTHIKANANKHKFTKEMTH
                     DEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKLKERKISKADPESGYYVKGER"
BASE COUNT          117 a           48 c           68 g           69 t
ORIGIN      
        1 tgaggatatt tttgcctata ttttagaaca agcagttaaa gcaggttttg taacagagga
       61 taatttgtat ctggattcta cccacatcaa agctaacgcc aataaacata agtttacgaa
      121 agaaatgacc catgatgaag cgaaagccta tcaggatgaa ttagaagatg agatcaatcg
      181 tcaacgaata gaggctggaa aacgcccttt tactttggac ttagaaaagg aagtgaagct
      241 gaaagaaaga aaaataagta aagctgatcc ggaaagcggc tactacgtca aaggcgaacg
      301 ag
//
LOCUS       DAXQKX010000239          298 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.263, whole genome shotgun sequence.
ACCESSION   DAXQKX010000239 DAXQKX010000000
VERSION     DAXQKX010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 298)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 298)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..298
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.263"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..159
                     /locus_tag="ACF3MF_002975"
     CDS             <1..159
                     /locus_tag="ACF3MF_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HFE3928837.1"
                     /translation="SQLLEVNLLNQLKLAKRVNLFDYSLEELQAVHEYWRSMNRYSKQ
                     VLNKEKVA"
BASE COUNT          109 a           41 c           57 g           91 t
ORIGIN      
        1 tctcaattat tggaagtcaa tttattaaac caattaaagc ttgcaaaacg tgtaaatctt
       61 tttgattatt ctttagaaga attacaagcc gttcatgagt attggcggtc aatgaatcgt
      121 tactcaaaac aagttttgaa taaagagaaa gtggcttaat atggcaaata tagtcaattt
      181 tactgacaaa caatttgaga atcgcttaaa tgataattta gaagaattga ttcaaggaaa
      241 aaaagcggtt gaatcgccaa ccgctttttt acttggtggg caaccagggt cagggaaa
//
LOCUS       DAXQKX010000240          289 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.264, whole genome shotgun sequence.
ACCESSION   DAXQKX010000240 DAXQKX010000000
VERSION     DAXQKX010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.264"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..>289
                     /locus_tag="ACF3MF_002976"
     CDS             <1..>289
                     /locus_tag="ACF3MF_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFE3928838.1"
                     /translation="HKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNF
                     FKSITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNGL"
BASE COUNT           92 a           59 c           48 g           90 t
ORIGIN      
        1 tcataaaagt gccgtcatta ctttagttga aagattatct aaagtcatta tcacgattaa
       61 acccaacggc cgtaaggcat tagatattga aactgccctt aatcaatggt tttctcgctt
      121 ccctaaaaac ttctttaaat ctattacgtt tgactgtgga aaagaatttt ctaactggaa
      181 agccattagt aaccaacatg atattgatat atattttgcg gaccctggaa caccttctca
      241 acgcccatta aacgagaatt ctaacgggat tctgcgtcgt aatggactg
//
LOCUS       DAXQKX010000241          287 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.265, whole genome shotgun sequence.
ACCESSION   DAXQKX010000241 DAXQKX010000000
VERSION     DAXQKX010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..287
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.265"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
BASE COUNT           66 a           77 c           56 g           88 t
ORIGIN      
        1 catcatccgc gttcaaagtt tcgctgtttg tgttcggtga aatagacgcc tcaatcgcct
       61 taccgatctt aaccggttta tcgtaagtgg cgcccgcttc atcgtcctta atcaatttcg
      121 caaagtaaat atcacgtaat cccatgcgtg ttcctgccaa atttattcct cctccgtatt
      181 ttgcgcataa taaaaacgga gaaccttgtg gtagatctcc gtttcgtgtt cgtataggtc
      241 gtactgccct aagcgcccaa agcccgcatc gacgagttgc ttcttaa
//
LOCUS       DAXQKX010000242          273 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.266, whole genome shotgun sequence.
ACCESSION   DAXQKX010000242 DAXQKX010000000
VERSION     DAXQKX010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..273
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.266"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..>273
                     /locus_tag="ACF3MF_002977"
     CDS             <1..>273
                     /locus_tag="ACF3MF_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="Rib/alpha-like domain-containing protein"
                     /protein_id="HFE3928839.1"
                     /translation="SDADKYNPEGQKVTTELNKEPDASEGIKNKEDLPKDTKYTWKEK
                     VDVSAAGNKKGTVVVTYPDGSSDEVEVDVTVTDNRSDADKYEPTVEG"
BASE COUNT          111 a           39 c           64 g           59 t
ORIGIN      
        1 atctgacgct gacaaatata atcctgaagg tcaaaaagtg actacagaat tgaataagga
       61 accagacgca tctgagggaa ttaagaacaa agaagattta ccaaaagata ctaagtatac
      121 ttggaaagaa aaagtagatg ttagcgcagc tggaaataaa aaagggactg ttgtagtgac
      181 atatccagat ggatcatctg atgaagttga agtagatgtt acagtgacag acaatcgttc
      241 tgacgccgat aaatatgagc caacagtaga agg
//
LOCUS       DAXQKX010000243          271 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.267, whole genome shotgun sequence.
ACCESSION   DAXQKX010000243 DAXQKX010000000
VERSION     DAXQKX010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..271
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.267"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..>271)
                     /locus_tag="ACF3MF_002978"
     CDS             complement(<1..>271)
                     /locus_tag="ACF3MF_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFE3928840.1"
                     /translation="ITRHVWGDLMDEVEHLRLTDLNKSIYKKRKQTIERIFADAKEKH
                     GMRWTKYRGLEKVATHTMLVFAAMNLKKLATWLWKGKEPLFFCSKI"
BASE COUNT           68 a           65 c           43 g           95 t
ORIGIN      
        1 aatttttgaa caaaaaaata aaggctcctt gcctttccat agccaggtgg ctaatttctt
       61 taaattcatt gcagcaaaca ctagcatcgt atgcgtcgcg actttttcca agcctcgata
      121 cttggtccaa cgcatcccat gcttttcttt tgcatccgca aatattcgtt caatcgtttg
      181 tttccgtttt ttgtaaattg atttattcag atctgttagg cgaagatgtt ccacttcatc
      241 catcagatct ccccaaacat gtctcgtgat g
//
LOCUS       DAXQKX010000244          257 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.269, whole genome shotgun sequence.
ACCESSION   DAXQKX010000244 DAXQKX010000000
VERSION     DAXQKX010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..257
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.269"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..248
                     /locus_tag="ACF3MF_002979"
     CDS             <1..248
                     /locus_tag="ACF3MF_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928841.1"
                     /translation="MMYFNIGPKVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDL
                     FFKGRYVTSTPFDEDLSFVNKKKCSYAYVKAIKAVVR"
BASE COUNT           93 a           37 c           49 g           78 t
ORIGIN      
        1 acatgatgta tttcaatatt ggtcctaaag ttcacgagga attagacttt tgttttgcta
       61 ctgatccaat agaaaaagtt aaagaagtaa aaatcttaca caatgctgga gtaacaacaa
      121 acgatgaaga tttatttttc aaagggagat acgtgacttc tacgcctttt gatgaagatt
      181 tatcatttgt aaacaagaaa aaatgctctt acgcatatgt taaagcaatt aaggcggtgg
      241 ttagatgacg cctgaac
//
LOCUS       DAXQKX010000245          254 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.270, whole genome shotgun sequence.
ACCESSION   DAXQKX010000245 DAXQKX010000000
VERSION     DAXQKX010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..254
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.270"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..>254)
                     /locus_tag="ACF3MF_002980"
     CDS             complement(<1..>254)
                     /locus_tag="ACF3MF_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="relaxase"
                     /protein_id="HFE3928842.1"
                     /translation="VLNEHGLESVNNEYYENLEKRTNLYSNDPSKMKYGKINYQEFVQ
                     NAIEATLEKCEVNSFEDFSDHLAKEYNIEVYQFSKTNNKL"
BASE COUNT           74 a           43 c           33 g          104 t
ORIGIN      
        1 caagtttgtt atttgttttt gaaaattgat aaacttcaat gttatattct tttgccaaat
       61 gatccgaaaa atcttcaaaa gaattcactt cgcatttttc caacgttgct tcgatcgcat
      121 tttgcacaaa ctcttgataa ttaatttttc catatttcat cttagaagga tcgtttgaat
      181 aaagattggt tctcttttct aagttttcat agtactcatt attcactgat tcaagaccat
      241 gttcattgag gact
//
LOCUS       DAXQKX010000246          251 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.272, whole genome shotgun sequence.
ACCESSION   DAXQKX010000246 DAXQKX010000000
VERSION     DAXQKX010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..251
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.272"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..>251
                     /locus_tag="ACF3MF_002981"
     CDS             <1..>251
                     /locus_tag="ACF3MF_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFE3928843.1"
                     /translation="MVSGTQNGLDKTHELGDNMAEYSQLWSQMGYSADETFGMLQNGL
                     DAGAYNLDKVNDLVKEMGISLTDGRFEQNMDMFSESTRKA"
BASE COUNT           89 a           32 c           62 g           68 t
ORIGIN      
        1 atggtttcgg gtactcaaaa cggtttagat aaaacgcacg aattaggcga caatatggca
       61 gaatatagcc aattatggag tcaaatggga tattcagctg atgaaacgtt cggaatgctt
      121 caaaatggtt tagatgcggg tgcttataac cttgataaag tcaatgactt agttaaggaa
      181 atgggaatat cgttaacaga tggtcgattt gagcaaaaca tggatatgtt tagtgaaagt
      241 actagaaaag c
//
LOCUS       DAXQKX010000247          231 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.273, whole genome shotgun sequence.
ACCESSION   DAXQKX010000247 DAXQKX010000000
VERSION     DAXQKX010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..231
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.273"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(<1..>231)
                     /locus_tag="ACF3MF_002982"
     CDS             complement(<1..>231)
                     /locus_tag="ACF3MF_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFE3928844.1"
                     /translation="IDAALDFEFIYPIVEATYSDLGRPSIDPVILIKLVFIQYLFGIR
                     SMRQTIKEVDTNVAYRWFLGYSFEEKIPHFST"
BASE COUNT           77 a           43 c           54 g           57 t
ORIGIN      
        1 aagttgagaa atgggggatt ttctcctcga aggagtagcc taaaaaccag cggtaagcga
       61 cattggtatc gacttcctta atggtttgtc gcatggaacg gataccgaat aaatactgaa
      121 taaacaccaa tttgatcaga atcactggat cgatacttgg gcgacctaaa tcggagtaag
      181 tggcttcgac gattggataa ataaattcaa aatcaagcgc ggcatcaatc t
//
LOCUS       DAXQKX010000248          231 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.274, whole genome shotgun sequence.
ACCESSION   DAXQKX010000248 DAXQKX010000000
VERSION     DAXQKX010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..231
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.274"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
BASE COUNT           79 a           35 c           44 g           73 t
ORIGIN      
        1 agaaaaagca tggaatgcgc tgcatcaggt atcgaggctt agaaaaaaat caggtgcata
       61 cgatgcttgt ttttgccgaa atgagtctga aaaaattggt cacttagcag tgggagcata
      121 tgtcttcata ttttttatta tacaaaaata gacaaaagta tcagtctaca ctcttagtaa
      181 agaggaaact gatacttttg tctacagtat gatatttctt acatctactt t
//
LOCUS       DAXQKX010000249          226 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.denovo.275, whole genome shotgun sequence.
ACCESSION   DAXQKX010000249 DAXQKX010000000
VERSION     DAXQKX010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..226
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.denovo.275"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..>226
                     /locus_tag="ACF3MF_002983"
     CDS             <1..>226
                     /locus_tag="ACF3MF_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HFE3928845.1"
                     /translation="VHHSTCNEAKTTNVLNRKFLRDNPLEAIVTDLTYVRVGKKWNYV
                     CFILDLFNREILGYSCGEHKDAVLVKKAFSR"
BASE COUNT           78 a           39 c           44 g           65 t
ORIGIN      
        1 agtacatcat tctacttgca atgaagccaa aacgacaaac gtattgaatc gtaaattctt
       61 aagagacaac ccattagaag cgatcgtaac agacttgact tatgtacgag tcgggaaaaa
      121 atggaattat gtctgtttca ttttggatct gttcaatcga gaaattctcg gctattcttg
      181 tggagaacat aaagatgccg ttctagtaaa aaaagcattt agccgt
//
LOCUS       DAXQKX010000250        22842 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.guided.045, whole genome shotgun sequence.
ACCESSION   DAXQKX010000250 DAXQKX010000000
VERSION     DAXQKX010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22842
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.guided.045"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..666
                     /locus_tag="ACF3MF_002984"
     CDS             <1..666
                     /locus_tag="ACF3MF_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HFE3928846.1"
                     /translation="DTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAIISRLSDQG
                     YNLVIEGTGRTTDVPIQTATMLQAKGYETKMYVMAVPKINSYLGTIERYETMYADDPM
                     TARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETPSISAKETL
                     ERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKLESLQPPIPPIPKTPKL
                     PGL"
     gene            1103..1420
                     /locus_tag="ACF3MF_002985"
     CDS             1103..1420
                     /locus_tag="ACF3MF_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928847.1"
                     /translation="MEKTKKLQLEDFTENEFFGTQEQQYLKAQVREELKEQGFIIDSS
                     FEGDFKTWIGVYARPKDKPTYLDPQNDKEAEEQEQYSINGFKQDFSEWFEWEIKNLKI
                     KEM"
     gene            1459..1956
                     /locus_tag="ACF3MF_002986"
     CDS             1459..1956
                     /locus_tag="ACF3MF_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaJ domain-containing protein"
                     /protein_id="HFE3928848.1"
                     /translation="MKYIKNVETLEELKKAYKKLALKLHPDCGGSNEEMAQLNNEYDE
                     LFVKLKNTHKNKDGETYTKETTETPEQFKDIINQLFNLKMDGVSIEIVGTFIWLTGNT
                     KPYKDDIKALEFRYSPKKYAWYKAPSDYKKRSRKNYDMDTIRGMYGSQKVKEDKEEKK
                     YLQAN"
     gene            complement(2046..2237)
                     /locus_tag="ACF3MF_002987"
                     /pseudo
     CDS             complement(2046..2237)
                     /locus_tag="ACF3MF_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001281642.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            2161..2433
                     /locus_tag="ACF3MF_002988"
     CDS             2161..2433
                     /locus_tag="ACF3MF_002988"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928849.1"
                     /translation="MLNALELNRGFLFLWSFSLKIILARKNGTLLEALRAELPAFEQT
                     IVPEFKGAVRAVLKKIHRPSIGVKMGEIANYSSTSSPMGQLKKMFG"
     gene            2604..3182
                     /locus_tag="ACF3MF_002989"
     CDS             2604..3182
                     /locus_tag="ACF3MF_002989"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFE3928850.1"
                     /translation="MKTKDLIIEEFIKSFGENGFEGTSVDYLAKQVGIKKGSIYTHYS
                     GKNEIFTIACEKILDKCIVAIKQLLEVERDKPLDEQLFILLKTVCLESDFLTADEIAF
                     SKRVAILSSSELLSLVDKLLAKYDNFIDDTVSRIFIDCAKQKMLAEEEITSAISVYRM
                     LLENLYIDSLANQNCNEKLNHLWRYFWKGVCS"
     gene            3214..3657
                     /locus_tag="ACF3MF_002990"
     CDS             3214..3657
                     /locus_tag="ACF3MF_002990"
                     /inference="COORDINATES: protein motif:HMM:NF018410.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small multi-drug export protein"
                     /protein_id="HFE3928851.1"
                     /translation="MEIIKYIGAAFSTWFIGFFPYFEIYIAIPAGFAAGLNWFDAFLW
                     ASLGNWMVIPFVDICYEWLMKFNFMKKIMEKSLNGKWENRIEKHGAWVILLLTPLAGV
                     WTIGVIAKALKFNRAKLWIYSATSVGITGLIITILIINGITLNNS"
     gene            3810..3995
                     /locus_tag="ACF3MF_002991"
     CDS             3810..3995
                     /locus_tag="ACF3MF_002991"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928852.1"
                     /translation="MSTLQEKQLQFNPHLLRNEEIFRGASIYKIITIDMMKQIKARDK
                     QIELAENIVDYLLHTNF"
     gene            complement(4079..7045)
                     /locus_tag="ACF3MF_002992"
     CDS             complement(4079..7045)
                     /locus_tag="ACF3MF_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HFE3928853.1"
                     /translation="MKIARGRELLTPEQRQAFMQIPEDEWILGTYFTFSKRDLEIVNK
                     RRREENRLGFAVQLAVLRYPGWPYTHIKSIPDSVIQYISKQIGVSPSSLDHYPQRENT
                     LWDHLKEIRSEYDFVTFTLSEYRMTFKYLHQLALENGDAIHLLHECIDFLRKNKIILP
                     AITTLERMVWEARAMAEKKLFNTVSKSLTNEQKEKLEGIITSQHPSESNKTILGWLKE
                     PPGHPSPETFLKIIERLEYIRGMDLETVQISHLHRNRLLQLSRLGSRYEPYAFRDFQE
                     NKRYSILTIYLLQLTQELTDKAFEIHDRQILSLLSKGRKAQEEIQKQNGKKLNEKVIH
                     FTNIGQALIKAREEKLDVFKVLESVIEWNTFVSSVEEAQELARPADYDYLDLLQKRFY
                     SLRKYTPTLLRVLEFHSTKANEPLLQAVEIIRGMNESGKRKVPDDSPVDFISKRWKRH
                     LYEDDGTTINRHYYEMAVLTELREHVRAGDVSIVGSRQYRDFEEYLFSEDTWNQSKGN
                     TRLSVSLSFEDYITERTSSFNERLKWLAANSNKLDGVSLEKGKLSLARLEKDVPEEAK
                     KFSASLYQMLPRIKLTDLLMDVAHITGFHEQFTHASNNRKPDKEETIIIMAALLGMGM
                     NIGLSKMAEATPGLTYKQLANVSQWRMYEDAMNKAQAILVNFHHKLQLPFYWGDGTTS
                     SSDGMRMQLGVSSLHADANPHYGTGKGATIYRFTSDQFSSYYTKIIHTNSRDAIHVLD
                     GLLHHETDLNIEEHYTDTAGYTDQIFGLTHLLGFKFAPRIRDLSDSKLFTIDKASEYP
                     KLEAILRGQINTKVIKENYEDVLRLAHSIREGTVSASLIMGKLGSYSRQNSLATALRE
                     MGRIEKTIFILNYISDESLRRKIQRGLNKGEAMNGLARAIFFGKQGELRERTIQHQLQ
                     RASALNIIINAISIWNTLHLTTAVEYKKRTGSFNEDLLHHMSPLGWEHINLLGEYHFN
                     SEKVVSLNSLRPLKLS"
     gene            7191..7766
                     /locus_tag="ACF3MF_002993"
     CDS             7191..7766
                     /locus_tag="ACF3MF_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFE3928854.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            8075..9388
                     /locus_tag="ACF3MF_002994"
     CDS             8075..9388
                     /locus_tag="ACF3MF_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003141076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380 family transposase"
                     /protein_id="HFE3928855.1"
                     /translation="MATLHENRLLFNSNVTVSHSGGNLSSDSGLILAKEFMNKFEFSQ
                     ILCKNIQIQDDRLYHVHENESILEQIILQLIAGYPTDSSANILATDPIFQAVLSKKRL
                     ASQSSISRFWDRISTENIVQLQKVNQILIDKARTIRNTNEMIFDLDSTHSDTFGNQEM
                     TDYNAHYQTTGYHPLVAFDGLTGDFLKAELRSGNVYTSKGVAAFTRPLFEHYHSVTPV
                     STIMVRADSGFAMPDLYELCEEYDSLYTIRLKSNRNLYRIADQFITIKDHHDWSKKEV
                     HYYNATYQAKSWGKSRRICIKSTREASELLFRHEFIITNFSKDVSPEMVFQTYSKRGT
                     MENYIKEAKNGFYLDKTDSPRFIENHARMIVSLLAYNIVNFMRTLCFTNETKGYQVST
                     IRLFLFKIAGKIVHSGRRQYLKLSSYHVYQKLFYRILQNIQVLQC"
     gene            9660..10355
                     /gene="vanR-A"
                     /locus_tag="ACF3MF_002995"
     CDS             9660..10355
                     /gene="vanR-A"
                     /locus_tag="ACF3MF_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /protein_id="HFE3928856.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            10333..11487
                     /locus_tag="ACF3MF_002996"
     CDS             10333..11487
                     /locus_tag="ACF3MF_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-A"
                     /protein_id="HFE3928857.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            11702..12670
                     /locus_tag="ACF3MF_002997"
     CDS             11702..12670
                     /locus_tag="ACF3MF_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HFE3928858.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            12663..13694
                     /gene="vanA"
                     /locus_tag="ACF3MF_002998"
     CDS             12663..13694
                     /gene="vanA"
                     /locus_tag="ACF3MF_002998"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HFE3928859.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            13700..14308
                     /locus_tag="ACF3MF_002999"
     CDS             13700..14308
                     /locus_tag="ACF3MF_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HFE3928860.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            14758..15648
                     /locus_tag="ACF3MF_003000"
     CDS             14758..15648
                     /locus_tag="ACF3MF_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HFE3928861.1"
                     /translation="MLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHLENSGTSE
                     NTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLLDSNIYMS
                     KEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGYSEHNSGL
                     SLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIRYVGLPHS
                     AIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNLRYEISGN
                     NIDGVIVTVFPGSTHTNSRR"
     gene            15801..16286
                     /gene="vanZ-A"
                     /locus_tag="ACF3MF_003001"
     CDS             15801..16286
                     /gene="vanZ-A"
                     /locus_tag="ACF3MF_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HFE3928862.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            16556..16786
                     /locus_tag="ACF3MF_003002"
     CDS             16556..16786
                     /locus_tag="ACF3MF_003002"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928863.1"
                     /translation="MNKVHVYNHNKFVKEINSDTNSIAKEIASQSPFAELKMTDEYDN
                     LILTTKGFFLDDVPNQIWLKNELMPALTNLQI"
     gene            complement(16833..17096)
                     /locus_tag="ACF3MF_003003"
                     /pseudo
     CDS             complement(16833..17096)
                     /locus_tag="ACF3MF_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003043131.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(17121..18443)
                     /locus_tag="ACF3MF_003004"
     CDS             complement(17121..18443)
                     /locus_tag="ACF3MF_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001281642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFE3928864.1"
                     /translation="MSDLLSLPDIKTIEPPQENETDMMFKVEAVGPPERCPECGFDKL
                     YKHSSRNQLIMDLPIRLKRVGLQLNRRRYKCRECGSTFWERLISVDEKRSMTKRLLKS
                     IQEQSMSKTFVEVAESVGVDEKTIRNVFKDYVALKEREYQFETPKWLGIDEIHIIRRP
                     RLVLTNIERRTIYDIKPNRNKETVIQRLSEISDRTYIEYVTMDMWKPYKDAVNTILPH
                     AKVVVDKFHVVRMANQALDNVRKSLKAHMSQKERRTLMRERFILLKRKHDLNERESFL
                     LDTWLGNLPALKEAYELKEEFYWIWDTPDPDEGRLCYSQWRHRCMSSNSKDAYKDLVR
                     AVDNWHVEIFNYFDKRLTNAYTESINSIIRQVERMGRGYSFDALRAKILFNEKLHKKR
                     KPRFNSSAFNKAMLYDTFNWYEVNDHDITDNFGVDFSTLIKNLEKGDL"
     gene            complement(18685..20325)
                     /gene="merA"
                     /locus_tag="ACF3MF_003005"
     CDS             complement(18685..20325)
                     /gene="merA"
                     /locus_tag="ACF3MF_003005"
                     /EC_number="1.16.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016152 - mercury (II) reductase (NADP+)
                     activity [Evidence IEA];
                     GO_function: GO:0045340 - mercury ion binding [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0046689 - response to mercury ion [Evidence
                     IEA];
                     GO_process: GO:0050787 - detoxification of mercury ion
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mercury(II) reductase"
                     /protein_id="HFE3928865.1"
                     /translation="MNKFKVNIQGMTCTGCEKHVESALEKIGAKNIESNFRRGEAVFE
                     LPDDIEVESAIKAIDEANYQAGEIEEVSSLENVALINEDDYDLLIIGSGAAAFSSAIK
                     AIEYGAKVGMIERGTVGGTCVNIGCVPSKTLLRAGEINHLSKDNPFKGLQTSAGEVDL
                     ASLITQKDKLVSELRNQKYMDLIDEYNFDLIKGEAKFVDASTVEVNGAKLSAKRFLIA
                     TGASPSLPQISGLEKMDYLTSTTLLELKKIPKRLTVIGSGYIGMELGQLFHHLGSEIT
                     LMQRSERLLKEYDPEISESVEKALIEQGINLVKGATFERVEQSGEIKKVYITVNGSKE
                     VIESDQLLVATGRKPNTDSLNLSAAGVETGKNNEILINDFGQTSNEKIYAAGDVTLGP
                     QFVYVAAYEGGIITDNAIGGLNKKIDLSVVPAVTFTNPTVATVGLTEEQAKEKGYDVK
                     TSVLPLDAVPRAIVNRETTGVFKLVADAETLKVLGVHIVSENAGDVIYAASLAVKFGL
                     TIEDLTETLAPYLTMAEGLKLAALTFDKDVSKLSCCAG"
     gene            complement(20350..20742)
                     /gene="merR"
                     /locus_tag="ACF3MF_003006"
     CDS             complement(20350..20742)
                     /gene="merR"
                     /locus_tag="ACF3MF_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0045340 - mercury ion binding [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0046689 - response to mercury ion [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hg(II)-responsive transcriptional regulator"
                     /protein_id="HFE3928866.1"
                     /translation="MIYRISEFADKCGVNKETIRYYERKNLLQEPHRTEAGYRIYSYD
                     DVKRVGFIKRIQELSFSLSEIYKLLGVVDKDEVRCQDMFEFVSKKQKEVQKQIEDLKR
                     IETMLDDLKQRCPDEKQLHSCPIIETLT"
     gene            21012..21245
                     /locus_tag="ACF3MF_003007"
     CDS             21012..21245
                     /locus_tag="ACF3MF_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928867.1"
                     /translation="MRGINNHQKYDFDLYQIEARSPMSTREITLTVDFIEKKVSGDII
                     AFGDWYDLDIESVNEILKQLKKEGQTLRTINFI"
     gene            complement(21268..21525)
                     /locus_tag="ACF3MF_003008"
     CDS             complement(21268..21525)
                     /locus_tag="ACF3MF_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928868.1"
                     /translation="MANNDLNDINKRIEKLKIQKNILRANSEQNINRKRRTKRLIEKG
                     ALLEKYFEIDYLTVEETEEFLKIFSEYIKANKPKKYQKKEK"
     gene            complement(21528..21827)
                     /locus_tag="ACF3MF_003009"
     CDS             complement(21528..21827)
                     /locus_tag="ACF3MF_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFE3928869.1"
                     /translation="MENQDQNINAINGNFNSKTKPKKRKKKTVSDIELQIKELQKKKE
                     ELILKSKADIGDFVLSTLSKLDISIESIEENKELFYDELETLLNANSQNFSELLK"
     gene            22119..>22842
                     /gene="mobQ"
                     /locus_tag="ACF3MF_003010"
     CDS             22119..>22842
                     /gene="mobQ"
                     /locus_tag="ACF3MF_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobQ family relaxase"
                     /protein_id="HFE3928870.1"
                     /translation="MAIFHLSMTIAKREGGKRSLIAMASYRSGEKLYSELYEKTNLYN
                     HRTVKPEAFILKPDYVPNEFLDRQTLWNKMELAEKQVNSQLCREVNVALPIELNNTDQ
                     RSLIEEFVKDNFVSEGMIADVAIHRDDENNPHAHIMLTMREVDSEGNILNKRKKIPKL
                     DENGNPILLENGKIKMVSIKTNDWDRKSLVSEIRKDWADKVNQYLKDRNIDQQITEKS
                     HAELGKKELPTIHEGFYSKKLEE"
BASE COUNT         7535 a         4004 c         4198 g         7105 t
ORIGIN      
        1 gataccttta aacaacagca ccctaatttt gatgaactag tgaaacttta tgaaaaagac
       61 gtagtaaaac acgttacccc ctattctaat cgcatgacag aagcgatcat aagccgtttg
      121 agcgatcaag ggtataattt ggtgatcgaa ggtacaggac gaacaacaga cgttcctatt
      181 caaaccgcaa caatgcttca agccaaaggt tatgaaacaa aaatgtatgt catggcagta
      241 cctaaaatca actcatattt aggaacaatt gaacgatatg aaaccatgta tgcagatgat
      301 ccaatgacag ctagggcaac accaaaacaa gcgcatgata ttgttgtcaa aaacttaccg
      361 accaatttag aaacccttca taaaacgggc ttatttagcg atataaggct ttacaataga
      421 gaaggagtga aactctattc aagcttagaa acgccttcca ttagtgcgaa agagacctta
      481 gaaagagaat taaatcgtaa agtatcaggg aaagaaattc aaccgacttt ggagagaata
      541 gagcaaaaaa tggttcaaaa tcaacaccaa gaaacccctg aatttaaagc aattcaacaa
      601 aaattggaaa gcttgcagcc acctatacca ccaataccca aaacacctaa acttccagga
      661 ctttaaacct taaaaaagga aaagagtagt taccaaaaaa cggtaactac tcttttttta
      721 taaaaacctt tcctcatgtt tgaaaagctg atcgagaaat aaagcacaca acggtattct
      781 ttcttttttc agttggtaca ttttgcagtc tgtaacgtgt catttactgt ttgttacctt
      841 aacatatcca gtcgaaaaca caagggtata taaacgagca agctcgccct tgtgttttct
      901 ttgtgtctat gttgcgttct cgtcacagca aacgacacga acacactggc gaaaatgaac
      961 caactgaaaa aagaaaggag catacactgt aatttatttc tagcttttaa aacatgagga
     1021 aaacagcttc acttcctcaa acgcctaaca aaaatggttg tcaaaaaact aaaaatcaaa
     1081 aaaaagaaaa gaggaaaaga aaatggaaaa aacaaaaaaa ttacaattag aagattttac
     1141 agaaaatgag ttttttggaa cacaagaaca gcaatatcta aaagctcaag taagagaaga
     1201 gctaaaagag caaggcttta tcatagatag cagttttgag ggcgatttta aaacatggat
     1261 aggtgtatac gcaagaccaa aagataaacc gacctactta gaccctcaaa acgataaaga
     1321 agcagaagaa caagagcaat attctattaa cggctttaaa caagatttta gcgaatggtt
     1381 tgagtgggaa ataaaaaatt tgaaaattaa agaaatgtaa aaaaaagcca aaaatcaaaa
     1441 agaaaaggaa tgatgaaaat gaaatacatt aaaaacgttg aaacattaga agaattgaaa
     1501 aaagcctaca aaaagttagc tttgaaattg caccccgatt gtggtggtag caatgaagaa
     1561 atggcgcaac taaacaatga atatgatgaa ttgtttgtca agctaaaaaa cactcataag
     1621 aacaaagacg gcgaaaccta tacaaaagaa acgactgaaa cgcccgaaca atttaaggac
     1681 attataaatc aacttttcaa tctgaaaatg gacggtgtat caattgaaat cgtgggaact
     1741 tttatatggt taacaggcaa cacaaaacct tataaggacg acataaaagc cctagaattt
     1801 cgttattcac caaaaaaata cgcatggtat aaagcaccaa gcgattataa aaaacgtagt
     1861 cgaaaaaatt atgatatgga cacaataagg ggaatgtatg gaagtcaaaa ggtgaaggaa
     1921 gataaagaag aaaaaaaata cttacaagcc aattaaggct tgtaagtttg tcagaaagga
     1981 agttttaaag tggatattaa aataaaaaaa ataaagggta ttcggatttt atggtggaaa
     2041 agggcctata agttactctt ttccaatttc ttaataagtg tggaaaaatc tacaccatag
     2101 ttgcctgttt tgtctcggtc tgttatttga tacgaattga aactatcgta taacatagct
     2161 ttgctgaatg cacttgaatt aaatcgtggc ttcctctttt tatggagctt ttcattaaaa
     2221 attattttag ctcgtaaaaa cggaactctt ttagaagctt tgagagcgga actacctgca
     2281 tttgaacaaa ccattgtccc tgaatttaaa ggggctgtta gagctgtttt gaaaaagatt
     2341 catcgtcctt ctataggggt taaaatgggt gaaatagcta attatagttc cacatcaagt
     2401 ccaatgggac aactgaagaa aatgtttggg taacgaaaca cacagaatga gcaattttaa
     2461 tattaaaatt gaagagttac catctctaga gaaaagtttc cgccaaagta ttgacacata
     2521 caaatcacca ctattacttg acaaatggaa tcacctagta taaaatacta actaccggta
     2581 gttagtatta aggatggtga attatgaaaa caaaagattt aattattgaa gaatttataa
     2641 aatcctttgg tgaaaatgga tttgaaggaa cttctgttga ctatctagca aagcaagttg
     2701 gcataaagaa aggttctatt tatacccact atagtggaaa aaatgaaata tttactattg
     2761 cctgtgaaaa aatactagat aaatgtatcg ttgctataaa acaattgctt gaagtagaga
     2821 gggataaacc attagatgaa caacttttta ttttgcttaa aactgtctgt ctagaaagtg
     2881 attttttaac cgctgatgag atagctttca gcaagcgcgt tgcaatttta tctagcagtg
     2941 aattgttgtc gcttgtagat aaattattag caaaatatga taattttatt gacgacacag
     3001 tatcacgaat ttttattgat tgtgctaaac aaaaaatgtt ggcagaagaa gagataacgt
     3061 ctgccataag tgtatatcgt atgttgttgg aaaacttata tattgattca ttagcaaatc
     3121 aaaattgtaa tgaaaaattg aatcatttat ggagatattt ttggaaaggt gtttgcagtt
     3181 aaaaattaaa taaacttgat tggaggttta attttggaaa ttattaagta tattggagca
     3241 gcattttcaa cttggttcat aggttttttt ccttattttg aaatttatat tgcaatacct
     3301 gcaggttttg cagccgggct aaattggttt gacgcttttt tatgggcttc actaggaaat
     3361 tggatggtta ttccgtttgt ggatatatgc tatgaatggt taatgaaatt taatttcatg
     3421 aaaaaaatca tggaaaaaag tctaaatgga aaatgggaga atcgcataga aaagcatggt
     3481 gcatgggtta tacttttgtt aactccttta gcaggtgttt ggacaatagg tgttattgct
     3541 aaagcactaa agtttaatcg agcaaaactt tggatatata gtgcaactag tgttgggatt
     3601 actggattaa ttattacgat attaattata aatggaatta ccctgaataa ttcatagtac
     3661 cttgtcagaa caggcattta tcccgctttg ataaggttta tcactctatt ccttcttcac
     3721 ccgttgggtg aagaaaaaaa tatacaaaaa gagcacactc tatgttattg taaagtcgat
     3781 caaaacaaca aaaacaagag gtgtgctcaa tgtcaacttt acaagaaaag caactacaat
     3841 tcaatcccca tttgttgaga aatgaagaaa tatttcgtgg agcaagtatc tataaaatca
     3901 ttacgattga tatgatgaaa caaataaaag ctagagacaa gcaaattgaa ttagcagaaa
     3961 acattgttga ctacttatta catactaatt tctaagaata taaaggggta gcgtcaggaa
     4021 aatgcggatt tacaacgcta agcctatttt cctgacgaat ccctcgtttt taacaacgtt
     4081 aagaaagttt tagtggtctt aaagaattta atgagactac tttctctgag ttaaaatggt
     4141 attctcctag taaattaata tgttcccaac ctaagggcga catatggtgt aacaaatctt
     4201 cattaaagct acctgtccgt tttttatatt caactgctgt tgttaggtgg agagtattcc
     4261 aaatacttat agcattgata attatgttta aagcactggc tctttgcaat tgatgctgta
     4321 tggtgcgttc tctaagctca ccttgttttc cgaagaaaat agctcttgcc aatccattca
     4381 tggcttctcc tttattcaat cctctttgta tttttcttct taatgattca tccgatatat
     4441 aattcaaaat aaagatcgtt ttttctattc ggcccatctc acgtaaggct gtagctaagc
     4501 tgttttgtct tgaataggaa cctagcttcc ccataataag ggatgctgaa actgttccct
     4561 cccttataga atgagctaat cgcaaaacat cctcataatt ttctttaatg acctttgtat
     4621 ttatttgtcc acgtaaaatg gcttctagtt ttggatactc acttgcttta tctatcgtaa
     4681 ataattttga gtccgataaa tcccttattc ttggggcaaa tttaaatcct aataaatgag
     4741 tcagtccgaa tatttggtca gtgtaaccgg cagtgtctgt ataatgttcc tctatgttta
     4801 gatccgtctc atgatgtaac aaaccatcca aaacatgaat cgcatctctt gaattagtat
     4861 gaataatctt tgtgtagtaa gaagagaatt gatcacttgt aaatcggtag atggtggctc
     4921 cttttccagt tccataatgt ggatttgcat ctgcatgtag tgatgaaaca cctagctgca
     4981 ttctcatacc atctgacgaa gatgttgtac cgtcgcccca atagaaaggc aattgtaatt
     5041 tatgatgaaa gtttactaat atggcttggg ctttattcat ggcatcttca tacatgcgcc
     5101 attgagatac attggctagt tgcttatatg taagtccggg tgtggcttcg gccatcttgc
     5161 tcaagccaat attcattccc attcctaaaa gggcagccat gataatgatt gtttcttcct
     5221 tatctggttt tcgattattg gaagcatgag tgaattgctc atgaaatcct gttatatggg
     5281 ccacatccat gagtaaatca gttaatttta ttcttggtag catctgataa aggcttgcac
     5341 taaatttttt tgcttcttct ggaacatctt tttctaagcg tgcaagtgat agctttcctt
     5401 tttcaagaga aaccccatct aacttattgg aattggcagc taaccacttt aacctttcat
     5461 taaagctgct ggttctctcc gttatataat cttcgaatga taaactaact gataatctcg
     5521 tattcccctt cgattgattc catgtatctt ccgaaaacaa atattcctca aaatccctat
     5581 attgtctgct gccaacaatg gaaacatctc ctgcccgaac atgctcccga agttctgtta
     5641 aaacagccat ttcatagtaa tgacgattaa ttgttgtacc atcatcctcg tataaatgtc
     5701 ttttccatcg ttttgaaata aaatccacag gtgagtcatc aggcactttt cgctttccag
     5761 attcgttcat tcctcggata atctcaacag cttgtaaaag tggctcattt gcctttgtag
     5821 aatgaaattc caatactctt aatagcgttg gcgtatattt tcttagtgaa taaaaccgtt
     5881 tttgcagtaa gtctaaataa tcatagtcgg caggacgtgc aagttcctga gcctcttcta
     5941 ctgaagagac aaaggtattc cattcaataa ccgattctaa aaccttaaaa acgtctaatt
     6001 tttcctctct tgctttaatt aatgcttgtc cgatgttcgt aaagtgtata actttctcat
     6061 ttagcttttt accgttttgt ttctggattt cctcttgagc cttacgacct tttgataaca
     6121 aactaagtat ttgcctatca tgaatttcaa acgctttatc cgttagctcc tgagtaagtt
     6181 gtaataaata gatggttaat atcgaataac gtttattttc ttgaaagtca cggaatgcat
     6241 acggctcgta tcttgagcct aagcgagaca gctgcaacag gcggttacgg tgcaaatgac
     6301 taatttgcac tgtttctaaa tccattcctc gtatgtattc gagtcgttct attattttta
     6361 gaaaagtttc gggtgaagga tgacccggtg gctcttttaa ccaacccaat atcgttttat
     6421 tggattcgga tggatgctgc gaggtaataa tcccttcaag cttttctttt tgctcatttg
     6481 ttagagattt actaaccgta ttaaatagct tcttttcagc cattgccctt gcttcccaca
     6541 ccattctttc aagtgtagtg atagcaggca gtataatttt gttttttctt agaaaatcta
     6601 tgcattcatg cagtagatga atggcatcac cattttccaa agctaattga tgaaggtact
     6661 taaatgtcat tcgatattca ctcagggtaa aagttacaaa gtcgtattca cttcgaattt
     6721 ctttcaaatg atcccaaagt gtattttccc tttgaggata atgatcaagc gaggatggac
     6781 taacaccaat ctgtttcgat atatattgta tgaccgaatc tgggatgctt ttgatatgag
     6841 tgtatggcca accgggatac cgaagaacag ctaattgaac agcaaatcct aaacggtttt
     6901 cttccctcct tcgcttatta actatttcta aatcccgttt ggaaaaagtg aagtaggtcc
     6961 ccagtatcca ttcatcttca gggatttgca taaaagcctg tctctgttcc ggtgtaagca
     7021 attctctacc tctcgcaatt ttcattcagt atcattccat ttctgtattt tcaatttatt
     7081 agttcaatta tatatcaata gagtgtactc tattgataca aatgtagtag actgataaaa
     7141 tcatagttaa gagcgtctca taagacttgt ctcaaaaatg aggtgatatt ttgcggaaaa
     7201 tcggttatat tcgtgtcagt tcgactaacc agaatccttc aagacaattt cagcagttga
     7261 acgagatcgg aatggatatt atatatgaag agaaagtttc aggagcaaca aaggatcgcg
     7321 agcaacttca aaaagtgtta gacgatttac aggaagatga catcatttat gttacagact
     7381 taactcgaat cactcgtagt acacaagatc tatttgaatt aatcgataac atacgagata
     7441 aaaaggcaag tttaaaatca ctaaaagata catggcttga tttatcagaa gataatccat
     7501 acagccaatt cttaattact gtaatggctg gtgttaacca attagagcga gatcttattc
     7561 ggatgagaca acgtgaaggg attgaattgg ctaagaaaga aggaaagttt aaaggtcgat
     7621 taaagaagta tcataaaaat cacgcaggaa tgaattatgc ggtaaagcta tataaagaag
     7681 gaaatatgac tgtaaatcaa atttgtgaaa ttactaatgt atctagggct tcattataca
     7741 ggaaattatc agaagtgaat aattagccat tctgtattcc gctaatgggc aatattttta
     7801 aagaagaaaa ggaaactata aaatattaac agcctcctag cgatgccgaa aagccctttg
     7861 ataaaaaaag aatcatcatc ttaagaaatt cttagtcatt tattatgtaa atgcttataa
     7921 cctgaataat tcatagtttt tcaaaaacgt ttcaaaaacc ttgttataac agtctatttt
     7981 gtttcgttta ttcgcaccct ttgggtgtac aaaaagaacc ccaatctgct atggttaaag
     8041 tgactaaacc taaccaaaga aaggggttct ctcaatggca actttacacg aaaatcgtct
     8101 acttttcaat tcaaatgtta cagtatctca ctctggtgga aatttgtcct cagattccgg
     8161 cttaatatta gcaaaagaat tcatgaacaa atttgagttt agccaaatct tatgtaaaaa
     8221 catccagatt caagatgacc gactgtatca tgttcatgaa aatgaatcta ttctggaaca
     8281 aatcatcttg cagttgattg caggctatcc tacagattct tcagccaata tattagcaac
     8341 ggatcctatc tttcaagctg ttttaagcaa aaagcggttg gcttcacagt catccatttc
     8401 tcgcttttgg gatcggatat caacagaaaa tatcgtccag ctacaaaagg ttaaccagat
     8461 tttgattgat aaagcacgga cgattcgaaa tacgaacgaa atgattttcg atttagattc
     8521 tactcacagt gatacctttg gaaaccaaga aatgaccgat tataatgcgc attaccagac
     8581 aaccggttat catccactcg ttgcctttga tggtcttacc ggagactttc ttaaagcaga
     8641 acttcgttct ggaaatgtct acacctcaaa aggcgtcgca gcatttactc gtccattatt
     8701 tgagcattat cactctgtga caccagtaag cactattatg gtacgtgcag atagtggatt
     8761 cgcaatgcct gatttgtatg agctttgtga agagtacgat agtttgtata ctatccgttt
     8821 gaaatccaat cgtaatctgt acagaatcgc tgatcaattc attaccatta aggatcatca
     8881 cgattggagt aagaaagaag ttcattacta taacgccact tatcaagcaa agtcatgggg
     8941 aaaatccaga aggatctgca taaaatcaac cagagaagct agtgaattgc tttttagaca
     9001 tgaattcatc attactaatt tttcaaaaga cgtctctcca gaaatggttt tccaaacgta
     9061 ttcaaaaaga ggaacgatgg aaaattacat taaggaagca aaaaacggct tttacttgga
     9121 taaaacagat agcccacgtt ttatagaaaa tcatgctcgt atgatcgtaa gcctattggc
     9181 ttacaatatc gtgaacttca tgcggacact gtgttttacc aatgaaacga aagggtatca
     9241 ggtttctact attcgcttat ttctctttaa aattgctgga aagatagttc attccggaag
     9301 aagacaatac ttgaaattaa gtagttacca tgtttaccag aagctatttt atcggattct
     9361 acaaaacatt caggtactgc agtgttaatt gcgtttattg cgccattcaa aaaaattcgt
     9421 taaccatccg ataggatgag tgcgcccaaa atgaggtctt tcttgaactt aatcagttag
     9481 caaaaataaa ttaaaccctt tagaaaaata tttttgagaa aaagaaccat tgagcataaa
     9541 actaaacaga taattataaa atttggtagt ttataaaaag tatgaattat tcaggtataa
     9601 attcggccct ataatctgat aaattattaa gggcaaactt atgtgaaagg gtgataacta
     9661 tgagcgataa aatacttatt gtggatgatg aacatgaaat tgccgatttg gttgaattat
     9721 acttaaaaaa cgagaattat acggttttca aatactatac cgccaaagaa gcattggaat
     9781 gtatagacaa gtctgagatt gaccttgcca tattggacat catgcttccc ggcacaagcg
     9841 gccttactat ctgtcaaaaa ataagggaca agcacaccta tccgattatc atgctgaccg
     9901 ggaaagatac agaggtagat aaaattacag ggttaacaat cggcgcggat gattatataa
     9961 cgaagccctt tcgcccactg gagttaattg ctcgggtaaa ggcccagttg cgccgataca
    10021 aaaaattcag tggagtaaag gagcagaacg aaaatgttat cgtccactcc ggccttgtca
    10081 ttaatgttaa cacccatgag tgttatctga acgagaagca gttatccctt actcccaccg
    10141 agttttcaat actgcgaatc ctctgtgaaa acaaggggaa tgtggttagc tccgagctgc
    10201 tatttcatga gatatggggc gacgaatatt tcagcaagag caacaacacc atcaccgtgc
    10261 atatccggca tttgcgcgaa aaaatgaacg acaccattga taatccgaaa tatataaaaa
    10321 cggtatgggg ggttggttat aaaattgaaa aataaaaaaa acgactattc caaactagaa
    10381 cgaaaacttt acatgtatat cgttgcaatt gttgtggtag caattgtatt cgtgttgtat
    10441 attcgttcaa tgatccgagg gaaacttggg gattggatct taagtatttt ggaaaacaaa
    10501 tatgacttaa atcacctgga cgcgatgaaa ttatatcaat attccatacg gaacaatata
    10561 gatatcttta tttatgtggc gattgtcatt agtattctta ttctatgtcg cgtcatgctt
    10621 tcaaaattcg caaaatactt tgacgagata aataccggca ttgatgtact tattcagaac
    10681 gaagataaac aaattgagct ttctgcggaa atggatgtta tggaacaaaa gctcaacaca
    10741 ttaaaacgga ctctggaaaa gcgagagcag gatgcaaagc tggccgaaca aagaaaaaat
    10801 gacgttgtta tgtacttggc gcacgatatt aaaacgcccc ttacatccat tatcggttat
    10861 ttgagcctgc ttgacgaggc tccagacatg ccggtagatc aaaaggcaaa gtatgtgcat
    10921 atcacgttgg acaaagcgta tcgactcgaa cagctaatcg acgagttttt tgagattaca
    10981 cggtataacc tacaaacgat aacgctaaca aaaacgcaca tagacctata ctatatgctg
    11041 gtgcagatga ccgatgaatt ttatcctcag ctttccgcac atggaaaaca ggcggttatt
    11101 cacgcccccg aggatctgac cgtgtccggc gaccctgata aactcgcgag agtctttaac
    11161 aacattttga aaaacgccgc tgcatacagt gaggataaca gcatcattga cattaccgcg
    11221 ggcctctccg gggatgtggt gtcaatcgaa ttcaagaaca ctggaagcat cccaaaagat
    11281 aagctagctg ccatatttga aaagttctat aggctggaca atgctcgttc ttccgatacg
    11341 ggtggcgcgg gacttggatt ggcgattgca aaagaaatta ttgttcagca tggagggcag
    11401 atttacgcgg aaagcaatga taactatacg acgtttaggg tagagcttcc agcgatgcca
    11461 gacttggttg ataaaaggag gtcctaagag atgtatataa ttttttagga aaatctcaag
    11521 gttatcttta ctttttctta ggaaattaac aatttaatat taagaaacgg ctcgttctta
    11581 cacggtagac ttaataccgt aagaacgagc cgttttcgtt cttcagagaa agatttgaca
    11641 agattaccat tggcatcccc gttttatttg gtgcctttca cagaaagggt tggtcttaat
    11701 tatgaataac atcggcatta ctgtttatgg atgtgagcag gatgaggcag atgcattcca
    11761 tgctctttcg cctcgctttg gcgttatggc aacgataatt aacgccaacg tgtcggaatc
    11821 caacgccaaa tccgcgcctt tcaatcaatg tatcagtgtg ggacataaat cagagatttc
    11881 cgcctctatt cttcttgcgc tgaagagagc cggtgtgaaa tatatttcta cccgaagcat
    11941 cggctgcaat catatagata caactgctgc taagagaatg ggcatcactg tcgacaatgt
    12001 ggcgtactcg ccggatagcg ttgccgatta tactatgatg ctaattctta tggcagtacg
    12061 caacgtaaaa tcgattgtgc gctctgtgga aaaacatgat ttcaggttgg acagcgaccg
    12121 tggcaaggta ctcagcgaca tgacagttgg tgtggtggga acgggccaga taggcaaagc
    12181 ggttattgag cggctgcgag gatttggatg taaagtgttg gcttatagtc gcagccgaag
    12241 tatagaggta aactatgtac cgtttgatga gttgctgcaa aatagcgata tcgttacgct
    12301 tcatgtgccg ctcaatacgg atacgcacta tattatcagc cacgaacaaa tacagagaat
    12361 gaagcaagga gcatttctta tcaatactgg gcgcggtcca cttgtagata cctatgagtt
    12421 ggttaaagca ttagaaaacg ggaaactggg cggtgccgca ttggatgtat tggaaggaga
    12481 ggaagagttt ttctactctg attgcaccca aaaaccaatt gataatcaat ttttacttaa
    12541 acttcaaaga atgcctaacg tgataatcac accgcatacg gcctattata ccgagcaagc
    12601 gttgcgtgat accgttgaaa aaaccattaa aaactgtttg gattttgaaa ggagacagga
    12661 gcatgaatag aataaaagtt gcaatactgt ttgggggttg ctcagaggag catgacgtat
    12721 cggtaaaatc tgcaatagag atagccgcta acattaataa agaaaaatac gagccgttat
    12781 acattggaat tacgaaatct ggtgtatgga aaatgtgcga aaaaccttgc gcggaatggg
    12841 aaaacgacaa ttgctattca gctgtactct cgccggataa aaaaatgcac ggattacttg
    12901 ttaaaaagaa ccatgaatat gaaatcaacc atgttgatgt agcattttca gctttgcatg
    12961 gcaagtcagg tgaagatgga tccatacaag gtctgtttga attgtccggt atcccttttg
    13021 taggctgcga tattcaaagc tcagcaattt gtatggacaa atcgttgaca tacatcgttg
    13081 cgaaaaatgc tgggatagct actcccgcct tttgggttat taataaagat gataggccgg
    13141 tggcagctac gtttacctat cctgtttttg ttaagccggc gcgttcaggc tcatccttcg
    13201 gtgtgaaaaa agtcaatagc gcggacgaat tggactacgc aattgaatcg gcaagacaat
    13261 atgacagcaa aatcttaatt gagcaggctg tttcgggctg tgaggtcggt tgtgcggtat
    13321 tgggaaacag tgccgcgtta gttgttggcg aggtggacca aatcaggctg cagtacggaa
    13381 tctttcgtat tcatcaggaa gtcgagccgg aaaaaggctc tgaaaacgca gttataaccg
    13441 ttcccgcaga cctttcagca gaggagcgag gacggataca ggaaacggca aaaaaaatat
    13501 ataaagcgct cggctgtaga ggtctagccc gtgtggatat gtttttacaa gataacggcc
    13561 gcattgtact gaacgaagtc aatactctgc ccggtttcac gtcatacagt cgttatcccc
    13621 gtatgatggc cgctgcaggt attgcacttc ccgaactgat tgaccgcttg atcgtattag
    13681 cgttaaaggg gtgataagca tggaaatagg atttactttt ttagatgaaa tagtacacgg
    13741 tgttcgttgg gacgctaaat atgccacttg ggataatttc accggaaaac cggttgacgg
    13801 ttatgaagta aatcgcattg tagggacata cgagttggct gaatcgcttt tgaaggcaaa
    13861 agaactggct gctacccaag ggtacggatt gcttctatgg gacggttacc gtcctaagcg
    13921 tgctgtaaac tgttttatgc aatgggctgc acagccggaa aataacctga caaaggaaag
    13981 ttattatccc aatattgacc gaactgagat gatttcaaaa ggatacgtgg cttcaaaatc
    14041 aagccatagc cgcggcagtg ccattgatct tacgctttat cgattagaca cgggtgagct
    14101 tgtaccaatg gggagccgat ttgattttat ggatgaacgc tctcatcatg cggcaaatgg
    14161 aatatcatgc aatgaagcgc aaaatcgcag acgtttgcgc tccatcatgg aaaacagtgg
    14221 gtttgaagca tatagcctcg aatggtggca ctatgtatta agagacgaac cataccccaa
    14281 tagctatttt gatttccccg ttaaataaac ttttaaccgt tgcacggaca aactatataa
    14341 gctaactctt tcggcaggaa acccgacgta tgtaactggt tcttagggaa tttatatata
    14401 gtagatagta ttgaagatgt aaggcagagc gatattgcgg tcattatctg cgtgcgctgc
    14461 ggcaagatag cctgataata agactgatcg catagagggg tggtatttca caccgcccat
    14521 tgtcaacagg cagttcagcc tcgttaaatt cagcatgggt atcacttatg aaaattcatc
    14581 tacattggtg ataatagtaa atccagtagg gcgaaataat tgactgtaat ttacggggca
    14641 aaacggcaca atctcaaacg agattgtgcc gtttaagggg aagattctag aaatatttca
    14701 tacttccaac tatatagtta aggaggagac tgaaaatgaa gaagttgttt ttttttattg
    14761 ttattgttat tcttaatata cttaggttat gactacgtta atgaagcact gttttctcag
    14821 gaaaaagtcg aatttcaaaa ttatgatcaa aatcccaaag aacatttaga aaatagtggg
    14881 acttctgaaa atacccaaga gaaaacaatt acagaagaac aggtttatca aggaaatctg
    14941 ctattaatca atagtaaata tcctgttcgc caagaaagtg tgaagtcaga tatcgtgaat
    15001 ttatctaaac atgacgaatt aataaatgga tacgggttgc ttgatagtaa tatttatatg
    15061 tcaaaagaaa tagcacaaaa attttcagag atggtcaatg atgctgtaaa gggtggcgtt
    15121 agtcatttta ttattaatag tggctatcga gactttgatg agcaaagtgt gctttaccaa
    15181 gaaatggggg ctgagtatgc cttaccagca ggttatagtg agcataattc aggtttatca
    15241 ctagatgtag gatcaagctt gacgaaaatg gaacgagccc ctgaaggaaa gtggatagaa
    15301 gaaaatgctt ggaaatacgg gttcatttta cgttatccag aggacaaaac agagttaaca
    15361 ggaattcaat atgaaccatg gcatattcgc tatgttggtt taccacatag tgcgattatg
    15421 aaagaaaaga atttcgttct cgaggaatat atggattacc taaaagaaga aaaaaccatt
    15481 tctgttagtg taaatgggga aaaatatgag atcttttatt atcctgttac taaaaatacc
    15541 accattcatg tgccgactaa tcttcgttat gagatatcag gaaacaatat agacggtgta
    15601 attgtgacag tgtttcccgg atcaacacat actaattcaa ggaggtaagg atggcggaat
    15661 gaaaccaacg aaattaatga acagcattat tgtactagca cttttggggt aacgttagct
    15721 ttttaattta aaacccacgt taactaggac attgctatac taatgataca acttaaacaa
    15781 aagaattaga ggaaattata ttgggaaaaa tattatctag aggattgcta gctttatatt
    15841 tagtgacact aatctggtta gtgttattca aattacaata caatatttta tcagtattta
    15901 attatcatca aagaagtctt aacttgactc catttactgc tactgggaat ttcagagaga
    15961 tgatagataa tgttataatc tttattccat ttggcttgct tttgaatgtc aattttaaag
    16021 aaatcggatt tttacctaag tttgcttttg tactggtttt aagtcttact tttgaaataa
    16081 ttcaatttat cttcgctatt ggagcgacag acataacaga tgtaattaca aatactgttg
    16141 gaggctttct tggactgaaa ttatatggtt taagcaataa gcatatgaat caaaaaaaat
    16201 tagacagagt tattattttt gtaggtatac ttttgctcgt attattgctc gtttaccgta
    16261 cccatttaag aataaattac gtgtaagatg tctaaatcaa gcaatctgat ctttcataca
    16321 cataaagata ttgaatgaat tggattagat ggaaaacggg atgtggggaa actcgcccgt
    16381 aggtgtgaag tgaggggaaa accggtgata aagtaaaaag cttacctaac actatagtaa
    16441 caaagaaagc ccaattatca attttagtgc tgaggaattg gtctctttaa taaatttcct
    16501 taacgttgta aatccgcatt ttcctgacgg taccccataa aggagaataa ataaaatgaa
    16561 taaggtacat gtatataatc ataataaatt tgtaaaagaa attaatagcg acacgaatag
    16621 cattgctaaa gaaattgcta gtcaatcccc atttgctgaa ttaaaaatga cagatgaata
    16681 cgataactta attttaacaa caaaaggctt tttcctagat gatgtaccta atcagatatg
    16741 gctaaaaaat gagttaatgc cagctcttac aaatttacag atttaaaaaa taacctcacc
    16801 tgatcacatt agtataatta ggtgaggtta ttttatatat tgcgttgaat attatgttta
    16861 atcctatatc ttctaaatgt ttcatgatta ataccagtta aattttgaac ctctttgtct
    16921 gaatatccat tcttatataa ttcaaaagca tgctgtaatc tagggctatc ctttgtaaat
    16981 aaaggttttc tacctctata ttttttaccg tctttagcaa tctttattcc ctgggcttgt
    17041 ctttctttta tattctttcg ttcagattct gcttgatatt tatatatttc gggtattcgg
    17101 atttcatggt ggaaaagggc ttataaatca cccttctcca aattcttaat aagtgtggaa
    17161 aaatcgacac caaagttgtc tgtaatgtcg tgatcattca cttcatacca attgaaagta
    17221 tcgtataaca tagctttatt gaaagcactt gaattaaatc gtggcttacg ctttttatgg
    17281 agcttctcat tgaaaaggat tttggctcgt aaggcatcaa acgagtaacc tctacccatt
    17341 cgctctacct gcctaataat actgttaatt gactccgtat aagcgttagt gagcctttta
    17401 tcaaagtagt tgaatatttc gacatgccag ttgtctacgg ctctcacgag gtctttatat
    17461 gcgtctttag agttactgga catacaacgg tgtctccatt gactataaca aagacgacct
    17521 tcatctggat caggagtatc ccatatccag taaaactctt ctttgagttc ataggcttct
    17581 tttaaagcag gaagattacc taaccaagta tctaagagga atgattcacg ttcatttaga
    17641 tcgtgtttac gctttagaag gataaacctt tcacgcataa gggtacgtct ttctttttgg
    17701 ctcatatggg ctttcaaaga ctttctgacg ttatctaagg cttgattagc cattctaact
    17761 acatgaaact tatctacgac aactttagcg tgtggaagga tagtgttcac tgcgtctttg
    17821 taaggcttcc acatatccat tgtgacgtac tcaatataag tcctgtcact gatttctgaa
    17881 agacgttgga tgactgtttc cttgttacgg tttggcttga tgtcataaat agtcctgcgt
    17941 tcaatattag tcaatacaag ccgaggtcta cggataatat gtatctcgtc tatcccaagc
    18001 cacttaggag tttcaaactg gtattcacgt tctttgagtg ccacatagtc cttaaaaacg
    18061 ttcctaatag ttttctcgtc aacaccaacg ctttctgcga cttctacaaa ggtcttagac
    18121 atggattgct cttgaatgga ctttaaaagc cttttggtca tactacgctt ttcatctaca
    18181 gatattaggc gttcccagaa ggtagatccg cattcacgac acttgtatcg tctacggttc
    18241 aattgtaagc ccactcgctt taaacgaatg ggcaaatcca taattagttg atttcttgaa
    18301 ctgtgtttgt acaacttgtc aaaaccacat tcaggacaac gttcaggtgg tccgactgct
    18361 tcaactttaa acatcatatc ggtttcattt tcttgtggtg gttctattgt tttaatgtct
    18421 ggtagggata ataagtctga catattgttc atcctttatt actctgcggt gttaaggtat
    18481 caattataga tttgatgtcg aaatcatcat tgttaaatta tttttgtgac cacaaatgca
    18541 cttagaaaat cccttaaagc atttatataa tgggtgatcg caaaatagtg tatgaaatct
    18601 tttgtagact ttgctaaact actgcacacc tttagtacag tattagctgg ttcacttgaa
    18661 tagggagttg taaaaaaagt tcccttagcc tgcacaacaa gataatttcg aaacatcttt
    18721 atcgaacgta agtgcagcta attttagccc ttcagccatt gttaaatatg gtgctagggt
    18781 ttctgttaaa tcttctatcg ttaagccaaa tttaacagct aatgatgctg catagatgac
    18841 atctcctgca ttctcagata caatatgaac ccctaatact tttagtgttt ctgcatctgc
    18901 tactagttta aatacaccgg ttgtttcacg gtttacaatt gctcttggaa cagcatctaa
    18961 aggtaataca gatgtcttca catcataccc tttctctttt gcttgttctt ctgttaaacc
    19021 aaccgttgca accgtcggat tcgtaaacgt aacagcagga actaccgata aatctatttt
    19081 tttgtttaat ccaccgatag cattatcagt aataattcca ccttcatagg ctgctacata
    19141 tacaaattgc ggtcctaacg tcacatctcc tgctgcataa atcttttcat tacttgtttg
    19201 accaaaatca ttgatcagga tttcattatt ttttccagtt tcaacacctg ctgcacttaa
    19261 atttaaagaa tccgtatttg gttttcttcc agtggcaaca agtaactgat ctgattcaat
    19321 gacttcttta ctgccattta ctgttatgta aacctttttt atctctccac tttgttcaac
    19381 acgctcaaaa gttgcccctt tgacaaggtt tataccctgt tcaattaacg ctttttcaac
    19441 tgactctgaa atctcaggat catactcctt taaaagtcgc tcacttcttt gcataagcgt
    19501 tatttctgaa cctaaatgat gaaatagttg tccaagctcc attccaatgt atcctgagcc
    19561 aattacagtt aatcgttttg gtattttctt taactcaaga agtgttgtac tagttaaata
    19621 gtccattttt tcaagtcctg aaatttgggg caacgaaggc gatgcacctg ttgcaattaa
    19681 aaagcgtttt gcagataact ttgccccatt gacctcaacc gtactagcat caacgaattt
    19741 tgcttcacct ttaattaaat caaaattata ttcatcaatt aaatccatat atttttgatt
    19801 ccgaagttcg ctcaccaatt tatccttttg cgtgattaaa ctagctaaat ccacttctcc
    19861 agcggatgtt tgtaaacctt taaacggatt gtcttttgat aaatgattga tttcccctgc
    19921 cctaagaaga gtttttgacg gaacacagcc aatattcaca caggttcccc caaccgttcc
    19981 acgctcaatc attccaactt ttgcaccgta ttctatagct ttaattgccg aagaaaaggc
    20041 agcagcacca gaaccaataa taagaaggtc ataatcatct tcattaatta acgccacgtt
    20101 ttctagtgat gatacttctt caatttctcc ggcttggtaa tttgcttcat caatcgcctt
    20161 tattgcactt tcaacctcaa tatcatcggg cagttcaaat actgcttcac cacgacgaaa
    20221 attagactca atatttttag cacctatctt ttcaagtgct gattctacgt gtttttcaca
    20281 acccgtacaa gtcattcctt gaatgtttac cttaaattta ttcataaaaa agcccctttc
    20341 gttaatgtct catgttaatg tttctattat tggacacgaa tgtaattgct tttcatctgg
    20401 acatcgttgt tttaagtcgt ctaacatagt ttcaattcgt tttaaatcct ctatttgttt
    20461 ttgcacttcc ttttgttttt tagaaacaaa ttcgaacatg tcttgacaac gaacttcatc
    20521 tttatctaca acaccaagta atttataaat ctcgcttaaa gaaaaactaa gttcctgtat
    20581 tcgtttaata aacccaacac gcttaacgtc atcatatgaa tatatccgat aaccagcttc
    20641 cgttcggtga ggttcttgta ataaattttt tctctcgtaa tatctaatcg tttctttatt
    20701 aactccacat ttatctgcaa actcactaat gcgataaatc atcttatttc accccatgaa
    20761 tattataaac cgtgtaccat agtacgcggt caagtaaatt ggactatttt atttttcccc
    20821 aacgtatcac tcgtatgtga ttgatacttt tatataatac tattgattgt cctaacatcc
    20881 caccagaaaa tccgatttaa acaccagttg tttttaaact attaagaaag taattccact
    20941 atatattccg aagacccaaa ataaattttg aaggtaatat tttaaaagtt ataaaagcga
    21001 cagtaacaga aatgagagga ataaataatc atcaaaaata cgattttgat ttatatcaaa
    21061 tagaagcacg ttcgccaatg tcaacaagag aaataacttt aacagttgat tttatagaaa
    21121 aaaaagtatc aggtgatatt atcgcttttg gtgattggta cgatttggat atagaatcag
    21181 taaatgaaat attaaagcaa ttaaaaaagg aaggacaaac attaagaaca atcaatttta
    21241 tttaaaaaag tatcaaaaaa aggaaaatta tttttccttt ttttgatact ttttaggttt
    21301 attcgcttta atatattcag aaaaaatttt taaaaattct tccgtttctt ctacagttaa
    21361 atagtcaatt tcaaaatact tttctaacaa agcacctttt tcaattagac gttttgttct
    21421 tctttttctg ttaatatttt gctcgctatt cgctcgcaaa atattttttt gaatttttag
    21481 tttttctatt cttttgttga tgtcatttaa atcattattt gccataacta tttaagtaat
    21541 tcagaaaaat tttgactatt cgcatttaat aaagtttcta attcgtcata gaataattct
    21601 ttgttttctt caatcgattc aatagaaata tcaagttttg aaagagtaga aaggacaaaa
    21661 tcaccaatat ctgcttttga ttttagaatt aattcttctt ttttcttttg taattcttta
    21721 atttgaagtt caatatcaga aacagttttc ttctttcttt ttttgggctt agttttagaa
    21781 ttaaaattac cattaattgc attaatattt tgatcttgat tttccatgaa atacgcctcc
    21841 taatatatta tgtaactcta tcatattata ttatttttct aaaatcaata aatataaatg
    21901 aaaatgtcag attaaacata tttactttta taatgataag tggtaaaatt aatttatcaa
    21961 ggattccctt agatgattta ctaagggcgc acttataccc ctaaatttca tttagtggta
    22021 attgtgctat aaaacttaat ttacatttcg ttttatcgtc aagcgtgttt gttaaaattc
    22081 gctacgctca tgtttgaaaa gaaagagagg tgatacaatt ggcaatcttc catttatcta
    22141 tgacaatagc aaaaagagaa ggcggaaaaa gaagtttaat tgcaatggct tcttatcgaa
    22201 gcggtgaaaa attgtatagt gaactatatg aaaaaactaa tctatacaac catagaactg
    22261 ttaaaccaga agcttttatt ttaaagcctg attatgtacc taatgaattt ttagatagac
    22321 agactttatg gaacaaaatg gaattagcag aaaaacaggt gaattctcaa ctttgccgag
    22381 aagtaaatgt agcattgcca attgaattaa ataatacaga tcaacgatca ctgatagaag
    22441 aatttgttaa agataatttt gtcagcgaag gaatgattgc agatgtagct atccatagag
    22501 atgatgaaaa caatccccat gctcacatta tgctaacaat gagagaagta gatagtgaag
    22561 gaaatattct taacaagcga aaaaagatac ctaaactaga tgaaaatgga aacccgattt
    22621 tattagaaaa tggtaaaatt aaaatggttt ctattaaaac aaatgattgg gatagaaaat
    22681 ctcttgtttc tgaaattcgt aaagattggg ctgataaagt caaccaatat ttaaaagata
    22741 gaaatatcga tcaacaaatt acagaaaaat cgcatgcgga acttggaaaa aaagaactac
    22801 caacaattca tgaaggtttt tactcaaaaa aattagaaga aa
//
LOCUS       DAXQKX010000251        15911 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.guided.059, whole genome shotgun sequence.
ACCESSION   DAXQKX010000251 DAXQKX010000000
VERSION     DAXQKX010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15911)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15911
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.guided.059"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..427
                     /locus_tag="ACF3MF_003011"
     CDS             <1..427
                     /locus_tag="ACF3MF_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HFE3928871.1"
                     /translation="IKRDVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLRE
                     GQQGVTLRTFESMYFQKKLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKP
                     ILSELLEFYDAENWAKRFITNDSTIYEQYEYDLSSVENK"
     gene            complement(577..1518)
                     /locus_tag="ACF3MF_003012"
     CDS             complement(577..1518)
                     /locus_tag="ACF3MF_003012"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFE3928872.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            1644..2765
                     /locus_tag="ACF3MF_003013"
     CDS             1644..2765
                     /locus_tag="ACF3MF_003013"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFE3928873.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYSLGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            3023..4525
                     /gene="eat(A)"
                     /locus_tag="ACF3MF_003014"
     CDS             3023..4525
                     /gene="eat(A)"
                     /locus_tag="ACF3MF_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HFE3928874.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            4592..5119
                     /locus_tag="ACF3MF_003015"
     CDS             4592..5119
                     /locus_tag="ACF3MF_003015"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFE3928875.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            5330..6391
                     /locus_tag="ACF3MF_003016"
     CDS             5330..6391
                     /locus_tag="ACF3MF_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HFE3928876.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            6394..7290
                     /gene="murQ"
                     /locus_tag="ACF3MF_003017"
     CDS             6394..7290
                     /gene="murQ"
                     /locus_tag="ACF3MF_003017"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HFE3928877.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            7304..9286
                     /locus_tag="ACF3MF_003018"
     CDS             7304..9286
                     /locus_tag="ACF3MF_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HFE3928878.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(9351..9797)
                     /gene="nrdI"
                     /locus_tag="ACF3MF_003019"
     CDS             complement(9351..9797)
                     /gene="nrdI"
                     /locus_tag="ACF3MF_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HFE3928879.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            10008..11432
                     /locus_tag="ACF3MF_003020"
     CDS             10008..11432
                     /locus_tag="ACF3MF_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="basic amino acid/polyamine antiporter"
                     /protein_id="HFE3928880.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(11613..12386)
                     /locus_tag="ACF3MF_003021"
     CDS             complement(11613..12386)
                     /locus_tag="ACF3MF_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFE3928881.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(12383..13288)
                     /locus_tag="ACF3MF_003022"
     CDS             complement(12383..13288)
                     /locus_tag="ACF3MF_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFE3928882.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(13442..13762)
                     /locus_tag="ACF3MF_003023"
     CDS             complement(13442..13762)
                     /locus_tag="ACF3MF_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HFE3928883.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            14236..14922
                     /locus_tag="ACF3MF_003024"
     CDS             14236..14922
                     /locus_tag="ACF3MF_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HFE3928884.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            14924..15868
                     /locus_tag="ACF3MF_003025"
     CDS             14924..15868
                     /locus_tag="ACF3MF_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HFE3928885.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
BASE COUNT         5010 a         2813 c         3415 g         4673 t
ORIGIN      
        1 tataaaaaga gatgttacga ccaactattt cattcttcca catcgaggga atgaacaacc
       61 tggatatctt acttatgaag agtacctgaa aaaaacaggg gaatcgcgcg ggattctgga
      121 actgttgcgg gagggtcagc aaggagtgac tttgcggaca tttgaatcca tgtattttca
      181 aaagaaacta gtgacggata atcaagcgat tgctcattat catttttatc gtcctgaaaa
      241 tatttttttg cttcgagaac gtgatttaga tgaattaccg gaatttctgc atacaccatt
      301 taagccaatc ctatcagagc tattggaatt ttatgatgca gaaaattggg caaaacgatt
      361 tatcactaac gattccacta tttatgagca atacgaatat gacctctcct ctgttgaaaa
      421 caaataaaaa acctacattt tgaagagatt atgtactgaa acaaacaagc acaattctta
      481 tggcatcatg agagttgtgt tttctttttg atcttttatt gggcttaaaa aaagagaacc
      541 agctgctgat tcagctgatt ctcatcagag agccttttat tctgcgccaa ggattccttc
      601 ttttgcatgg actaattggg tcaaaaaggc acaatatggt gtagcaatat catatttttg
      661 tccttttcgc caaatggcac cattgatgta gtcgatttca gtcaaacgat ggtttttgat
      721 caggtcttgg tacatagatg ggtaatgcaa cccgatgttg tcaggatcat aagtagaagc
      781 aatatgttgg tacacttctt cttgatctag tatgattcct tcttttgctg cgatagaagc
      841 aaattcagat acgattgttc gaaccatgct ctctgccgct ttttgcgcgc ctagttcagc
      901 aatattacaa tccaaaatcg tgcataaacc attcaatgtt ccatttacac aagcttttcg
      961 ccaaatggaa taacgaacgt tatggctata gatcggattt aaatttgctt cttgaaagac
     1021 ttctacaact ttttttgtaa atgcttcgcc ttctggttcc aagttctcta gttcgatttc
     1081 tccatcacct aacaatgtga cttttccggg accagctaga ccagctgtcc acatcgtgat
     1141 cccaaataag atatttttct ttggcacata tttttccagt acatcttcat gacctaatcc
     1201 atttagtaaa cacaaaacat aagtattgtc agtaataatg gattggatcg aacaaaacat
     1261 atcatctaat tgattggctt ttgttaatgc tacgatcaag tccacgtgtt cgttgctttc
     1321 gatgatttct tctggtgaat agattggcag ttttgcgacc acttctttac cgttaaagtc
     1381 agcaatcaac ccatttgtac gaatggcttc aatgtgagca ggccaacgat cgatcaagag
     1441 gacctcattt ccgctttgat gtagcatcaa tccgattcgg ctgcccattg ctccggcccc
     1501 agctattgcg attttcatgt tttttctctc ctttattcaa tgagttccct tttagtatat
     1561 agaaaaatgg aagaaaatag cattgttttg tttgaaaaaa atgaaaaaaa gtgtcttact
     1621 taagaagaaa gtgagggata cagatggata ttttggcggc aattgattca tttaaaggaa
     1681 gtgcttcttc atttgaacta aatcaggcag ttctaaatgg ctgggaagat cgtaaaggaa
     1741 gaaaaatcaa tgtgccgatt gcagatggcg gagaaaatac tgcagaagca atctattacg
     1801 cgctcagggg aacatggcgt accattgatg ggatggatct cttattccgt cagcgaaaaa
     1861 tcagctattt attgacaact tggcaaggaa aaaacaccgc agtcatcgaa tctgcacaag
     1921 cattggggtt agatctactt gataaaccaa cggatcaaac tatccgactt gcttccagtt
     1981 attccttagg agaacttatt aaagatgcac tgcttcaaga agtagaacaa attattgtca
     2041 ctttaggagg aagcgggtgt agcgatggtg gtctaggatt actccaatcc ttgggtgctt
     2101 ctttagaagg gtacacagaa ggaaatcctt tattatctac taaaaaactt cattttgatc
     2161 gaagaaacgt tcttgtttct aaagtaaaat tgattatcgc tgcagatgtt accaatccat
     2221 atacaggtca acaaggagct gcttggcaat ttggaagaca aaaaggagga atagatacga
     2281 cgctagcttt cttagataaa caagcaggaa agattgctca gcaaataaaa gatttctggg
     2341 aggtggattt agatgatatt ccaggaagtg gagcagcagg cggtattggt ggagcccttt
     2401 ttttgttggg agcgaagatg gtttctggtt tcgatttagt cagccaaatc actggattgg
     2461 aaaaaaagat cgaacaagca gatgtcatca ttacaggaga agggcggatc gatcagcaaa
     2521 cgatccacgg aaaagttcca tacggtgtag cagtgcttgc aaaaaaatat cgaaaaccaa
     2581 taatcgctat ttgcggaagt agagaccaag agctagaagg actttctgat tttctcccaa
     2641 ttgtcttaag tattcatttg ggtccaatag gtttagaaga agcaatggaa cacaggcaaa
     2701 cattagaaaa aacaaaaatc ttaggacaga cacttagcag atttttcacc atcctcccga
     2761 agtagttgac aaaatcattt tctttatgct atcgtaattt caaatatagg acaaagtgag
     2821 ggatccgtgc attgaaaaat taagtcgatt gatgaaagct gcattcagac tgtaccttgt
     2881 ggagacaagg aagcagtgtg cagattttcg ggattggctt ggttttttcg atgtatgggt
     2941 ctttttgtgt gtatccaacc cttgcatcct ctttagccag ttctgaaaat aggactggtc
     3001 tttttttacg aggtgatgga aaatgtctaa aatcgaaata aaaaatctga cattcggcta
     3061 cgacagccaa ggcacattat tatttgaaca agcaaatcta aattttgaca cacaatggaa
     3121 actaggactt atcggacgaa acggtcgagg aaagacaact ttactgaata ttctacaaaa
     3181 caaactacct tatcaagggc aagtaatcca tcagcaagaa tttgcctatt tcccgcaaca
     3241 gacaaaagat aaagaacgtt taacctatta cgtgttaaat gatattacgg attttgagat
     3301 atgggaaatc gaaagagagc tccaattgat gcaaacagat cctgaaatct tatggagaga
     3361 attcagcaca ctatcggggg gagagaagac aaaagtccta ctggcacttt tatttgtgga
     3421 tgacactcat ttcccgttaa tcgatgaacc aacgaatcat ttggatatct ctggtagaaa
     3481 acaagtagcg gcttatttga aaaagaaaaa acaaggcttc atcgtggtca gccatgaccg
     3541 gggatttatc gatgaagtag tggaccatgt tttagcaatc gaaaaaagtc aactggaact
     3601 ttatcaaggg aatttctcta tctatgaaga acagaaaaaa cttcgtgatg aatttgaaat
     3661 ggctcaaaat gaaaaattga aaaaagaagt cagtaggcta aagaaaacag cagctgaaaa
     3721 agccgaatgg tctcgttccc gagaaggaga taaaacaaag aaacaagtcg gattcatcga
     3781 tactgaatct agacgagtga ataaaggagc agtgggtgct gatgctgcac ggacgatgaa
     3841 acgatccaaa gcaatcgtga atcggatgga gacccagatc agcgagaaag aaaaactatt
     3901 aaaagatatc gaatatatcg attctttgac gatgaatagc caagcgtctc accataagcg
     3961 acttttaagc gtagaagatc ttcaattagg gtatgaaaat ctgttattcg agccaattca
     4021 ttttacaatc gagcctcatc agcgggtggc gatttcaggt cctaacggtg caggaaagtc
     4081 atccattatc cattatcttc tgggggcatt caacggcaag gttataggag aaaaatacca
     4141 gccaaaacat ctgagcatta gttatgcaag ccaaaattat gaagacaatc gaggaacgtt
     4201 ggcggaattt gcagagaaaa accaagtaga ctaccaagca tttttgaaca acctccgaaa
     4261 gcttgggatg gaaagagatg tttttcataa caagatcgag cagatgagta tgggccaacg
     4321 gaaaaaagtg gaattggcta aatctttatc acagccagct gaactatata catgggatga
     4381 accattgaat tatttggatg tcttcaatca agaacaatta gaacaactga tcttgaacgt
     4441 gaaacctgcc atgttactag tggaacatga tcaaaccttc ctggataaag tatctactga
     4501 gattatttct cttgagagaa tctaaccctt gtaatctcaa gaacaacaag gtatggttaa
     4561 ggggaacttt gccaacgaag gagagaatca catgctttat gtaacgagac acggagaaac
     4621 aacttggaac gcacaaggat tagtttgcgg acgggcagat gtgccgctga ctgaaaaagg
     4681 acagatgcag gcacagaaac tagcagaaaa ggtagtagat ttgcctgttc caatcacgaa
     4741 aatcatccat tcccctcttc aacgagcaag agatacagca caagcagttg ctgatcgtct
     4801 cagcttgccg ctgaccgttg atgaacgatt ggtagaaatg gattttgggg attatgatgg
     4861 actgccaagc aaagatgaga actttcaaaa agcacgttta gcgttcgctg tacgattccc
     4921 aaatggggag tcagtcttag atgtgtatgc acggatcgtt cctttattga aagaatgcat
     4981 cgaagacgaa gaaaatgtct atctgttagt ttgccataat gccttgataa gagtgatcaa
     5041 tgcttatttt catccgatgc ctaatgaggg gttctttaca ttcatggtag ataatacaga
     5101 attggtttct tatgagtaat tatgtttttg tgttatttaa ataaaatatt tcaaggcact
     5161 gcttttgctt agcagtgcct tttttaggtt atgacaattc ttttgataat ataaactcaa
     5221 cctttagaaa tgaaatttaa ttattttaat aaaagtattg aaattttgtt tctttagata
     5281 tatactctag tcatagaaat gaagacggat acagaaaaag agggataata tgtttggctt
     5341 ttcaatattt atgaacgatt ctttgtcaga agagaagaaa cagtatatcc gccaaatggc
     5401 atccaatggc tttgtcggta ttttcacttc catgcatata ccagaagatg atgtttcggc
     5461 atatcaaaag cgattgatcg aactaggaag cgaagcgaaa aagaataaac tagaattgat
     5521 ggtcgatatt tcaggagagg cattggaacg agcgggtttt tcattagaag atctaacgcc
     5581 tttgaaagca attggtgtaa caggtttaag aatggattat catatttcca atcagcagat
     5641 tgccgactgg tcacatcaat tgaaaatcag tttgaatgct agcacgatca cgcctaaaga
     5701 tatcgatgaa ttgaaagaag cagaagctga tttctcacag attgaagctt ggcataatta
     5761 ttatccacgt cccgaaacag ggctggacaa agaatggtat cagaaaaaaa atcaatggct
     5821 caaaattcaa ggtctccttg tccaaggttt tgtaccagga gatacagagt tgagaggccc
     5881 actatatcaa ggattgccaa ctttggaaga acatcgaggg atccatcctc ttgcaggcgc
     5941 tctagatcta ttagcaagta acacggatat tgtttacatc ggagatgcag gtctgtcaga
     6001 aaacgttcag gagcaatttg cttctttcca aaaagaacag acagtcttgc tccatacgga
     6061 acctgtagat gaagaatttt acgaatatat attagggaag catacgaatc ggcaagacga
     6121 tgcaagagat gtcatacgaa gcgtagatgc acgttttcga gagattccgc ctatcccagc
     6181 aagaaataca gctacgcgta tgaaagggtc tattacttta gataacgaaa agtatttgcg
     6241 ctatatgggt gagatccaat taaccaaata tgatttgcca gcggatgaaa aagtgaatgt
     6301 agtagctaaa gttatcaaag aagagctacc attgatcaac caaatcaaag ctggtatgaa
     6361 ctatcaattt ataagaaaag aaggaagata aaaatgagca aaatcaattt agagaaccta
     6421 acaacggaac gcagaaacca agaaactttt ggattagatg agatgagtat ttctcaagcc
     6481 gttcaactaa tgaacaaaga agatcagaaa gtggccgctg cggttgaaaa agaactgaca
     6541 agtatcgaac cagtgattgc taacacgatt gagtccttta aaaaaggtgg acgtctgatt
     6601 tatatgggag ccggaacaag tggaagacta ggtgtgttag atgctgctga atgcgtaccg
     6661 acattcggtg tagaaccgga aatggtcata ggtctaattg ctggtggaga agaagcaatg
     6721 actgtagctg tcgaaggggc cgaagattct tatgagctag ggcaagaaga tctaatcaag
     6781 ctgaatttga caaaaaatga tatagttatt ggtatcgcag ctagcggtcg tacaccatat
     6841 gtgatcggtg gattagatta cgcaaaatcg atcggtgctg tcacaggaac gatttcttgc
     6901 aataaacaag ccgaaatcag taaacacgcg gatttcccaa tcgaagtcga tgcaggtcca
     6961 gaatttttga caggctctac tcgattgaag tcaggaacag cacaaaaact tatcttgaat
     7021 atgatttcta ctatcagtat gattggtata ggtaaagtat tcaataactt gatggtcgat
     7081 gtcaaaccaa caaatgaaaa actaatcgaa cgctcaaaac gaatcatcat gcaagcgaca
     7141 gaagctgatt acgaaacagc tgaaaagtac tttgaagaag cagatcaaaa tgttaagctg
     7201 gctatcgtca tgattttgac aaatagtgat aaagaggaag ctcaagcaaa attagctgaa
     7261 gcaaacggat ttgtaaaagg gaccttatga gggggaaaag accatggcaa aaaacgaact
     7321 gactttggaa gaactggcaa aacaaattta taaaggggca ggcggcatgg gcaatgtaga
     7381 aagcattgtc cactgcatga ctcgtgtgcg tatgaagatc atcaatgatg atcttgtaaa
     7441 tgtctctgaa ttaaaagcga ttccaggagt gcttggtgta gtagaagatg aacagcttca
     7501 agtcatcatc ggacctggga aagtgaacaa agtagcacag caaatggttg atttggcagg
     7561 cgtgaaatta ggagaaaaac tttcttctgt aagtacagct acagcaaatt catcagcatc
     7621 tggaaaagac cgtgtaaacg aacgggcaca agaaatgaaa gcggcacaaa aatcgaaaca
     7681 aaaaccatct aaaatcaaat cggtattaaa agacatttct aatatctttg tgccaatgat
     7741 tcctgcattt gtcggtactg ggatcgtggc agggattgcc gcagttttag caaacttagt
     7801 cacagccgga acacttgatg cagcaacatg gcaacaatat atcgatgtga tgaacatctt
     7861 gaaaaacggg atgtttagct acctagttat ctatacaggt atcaatgctg cacaagtttt
     7921 tggtgcaaca ccaactcttg gtggagttat cggggccgtt gtgatgctga cagggatgaa
     7981 tccggaagca ccactgaaaa acttatttac tggtgaagct cttgcagctg gacaaggtgg
     8041 gatcctaggt gtcatcttcg ctgtttggct attgtcaatc gttgagaaaa aactgcataa
     8101 agtagtacct gatgcggtag atatcatcgt tacaccaact ctttcattga ttgccatcgg
     8161 tctgattgaa attttcttca tcatgccttt agcaggtttc atttctgatg gcatggtcgg
     8221 tgggatcaac tgggtacttg gcgttggtgg agcatttgcc ggcttcgttc taggcacatt
     8281 attcttgccg atggttatgt tcggactgca tcaaattttg actccaatcc atgtgcaaat
     8341 gattgatgaa actggtcgta cgctattgct tccaattctt gcgatggctg gtgcaggaca
     8401 agtgggtgca gcattggcat tatggattcg ctgcaaaaaa gataaagaat taacagaaat
     8461 gatcaaagga gctttaccag tcgggatcct aggaatcggc gaaccattga tttacggagt
     8521 aacattacct ctaggacgcc catttattac tgcttgtatc ggtggaggta tcggcggggc
     8581 agtgatcgga atgatcggaa atgtcggggc tatcgctatt ggaccttcag gagccgcttt
     8641 gatcccattg atctctgacg gtaaatggtt aggctacatc cttggattat tggcagctta
     8701 tgctggtggc ttcgttgcta cattcttctt cggtattcct aaagaccgtt tagaaaaaga
     8761 agaattagcg actgaaacag ccacagtaaa tgaagtgcct gaaaaagtag tacctcaaac
     8821 ttcagctgaa agtgtgacta tcctctcatc agttgctgac ggaacagttg tttctttaga
     8881 taaagcaagt gatccagttt ttgcacaaaa gatgatgggt gaaggctact ttgtagaacc
     8941 agaaaacgga catatctatt ctccagttac tggggtagtc agctctgtct tcccaacgaa
     9001 acacgctatt gggatcacaa cgccaaatgg tttagaaatc ttgcttcata tgggaatcaa
     9061 cacagttgac ttaggcggta cgccatttga tgtgaaagta acagaagggc agcaagtgac
     9121 acctgatacg cttgtagcag aagctgactt agaagcgatc aaagcagcag gcaaagaaac
     9181 atccatgatc gtcttggtaa ccaatatgga tcgtgtaaaa aactttgtct tggaaaaaac
     9241 aggtaaagca aaagcaaaag cacctgtgat ggatgtcaaa gcttaatatg atagaaacaa
     9301 tagaaacgaa agaagaaact gaaatctatt tttcagcttc ttctttttta ttatttattg
     9361 ttttctgcta aaatctgata aattcgtgtc acatcagatg gtgttccccg taattcataa
     9421 tctgccaaga aaggaaagcc aaatgtttgt gcatattgtt tggctgttag acaatactga
     9481 ttattgaagt ttttatttcc gctaccgact acaccaagac aaagtttatg attgtcttca
     9541 tgttccagat attcacgcat cgtttcggtc aagatttctg tatcaccgtt atctaaacca
     9601 tttccgccgt ctaaataagt aggaacgaaa gtaaaaaatg gttctgtttc tttcgtaaaa
     9661 tcactatttt catggatttc ttttaaagta acttcaggat tgacaggatc ttctgcatgc
     9721 attttttcag catattctgc tagatgtttg gcaaaggcac gcgtatttcc tgaaatcgat
     9781 atatataaaa tgttcatgga tcatcctcca attctttcct tttagtatag catctttttt
     9841 aagttttttg gtggtgtaat ttggaaaggg actaggcgct ttgcttgtat aatgagaaaa
     9901 aagccggtag aattatattt ctattaaagt ttttattaat taagtaaaaa taaaaaaggt
     9961 ttgttatact ttttgataaa agcggtttta ttttggagga tgcttacatg gatacagagc
    10021 aacagaaaaa aggaattggt ttaattccac ttgctgcctt agtaattggt tcagcgattg
    10081 gaggtggcgt atttggtatt atgacggaca tctccggatc ggctggcggc ccagctattt
    10141 tcagttgggt actcgtagga acagcaatgt tgatgctctc cttgtcgatc aataatatca
    10201 ataaaaaacg tccagattta aaaggcggga tctttagtta cgcagaagaa ggttttggcc
    10261 gtttcgctgg ttttatcagc ggttggggtt actggctcac atgctggtta ggcaacgtag
    10321 cttttgcaac attgttgatg agcgcattag gatatttctt cccagtattt gaaggtgggc
    10381 aaaatctggc atcgatcgtg atgagtacag tctttttatg gggatatgca tggctagtga
    10441 atcggggagt cgaaaatgct agtttcgtca atgctatcgt cacattctgt aaattagtgc
    10501 cattattttt atttattgta gtagctatca gcacgttttc gatccaacaa ttcattgata
    10561 acttttctag cgacattata ttgaatgcga atggacagcc gatcccgttt tccagtcaag
    10621 tattgagttg catcatggtg atgctttggg tatttgttgg tattgaagga gcctctgtcg
    10681 taggttcacg agcaaaaaaa caatcagatg ttgggaaagc aacgattcta gggatattcg
    10741 gcttgattat tatttacgtc ttggtttcca tgcttccata tgggacaatg acgatgaatc
    10801 agctgcaaac gatcaaggcg cagcctgcta tgggctatgt gtttgaaatg atggttggta
    10861 aatggggagc agtcgtgatc aacggcggtt tgatcatttc tttagttggt gtttggctct
    10921 catggacgat cttaccgatt gaaacaatgg gaaacatggc tgaagacgga cttttgccta
    10981 aagcatgggg aaaactcaac aaaaatgggg caccaactta tgctatcgta ttgacgacgt
    11041 tatgtacgaa tgtcttttta ctttcattat tattcactga cagtgcttat aactttgctt
    11101 acacacttgg tacagcagct attttcttca cgtggctttt cttaggattg taccaaatga
    11161 aactttctta tcagcggaaa gaatgggtcc aatttttagt agggctttta gcaagtgcct
    11221 ttcaagtatg ggctatgcta gtcgtagcct ttaatgaagt aatgcttgtt cttgttcttt
    11281 tcttgccagg catttatttt tacctcaaag cacgtaagga gcaaaacgag cctgtacaac
    11341 atatccactt agataagatt ttacttatag gtgtgacgat ggtcggagtg attgcaatgg
    11401 ttttatttgc cactgggatg cttcacgtat agaagtataa aagaagtata aagagaggtt
    11461 gtgagcctgt cgtttattca aaaacatact aggaaaggag ctgtgacaca aatgttgtca
    11521 cagctccttt ttcagaataa acggtgttta agagacagcc aatcggcaat aaggctgaac
    11581 gtctctttca cagcctcttt tttgatgagt catcatacat tttttcgctt aaatacgaga
    11641 tatcctaatg ctaagaacaa aacgatgtaa gctaaattac cgaatagcat ttgattagta
    11701 gaaagatgag tcaattgctt catgatctct tcgtttccaa tttggttttg cagattcaac
    11761 atactgatcg gattccattt gatccactcc catttttgga tgagtgcaat aaggatacca
    11821 gatatgattg acgaagcaaa ataaaagacg attcctgctg agatggatgc accggaacta
    11881 ttgataaagc aagcaatcat caacactaaa cttaaaatca gccataaacc gatataacta
    11941 cccaaagtat aagtgaacaa gctttggatc agtgtttgac cagtagaaac cttctccgtg
    12001 aaggaaatcg aagggaaaag aatcagtttc atcaacacag tgacaataat agctaaaagg
    12061 tataaataaa cagaataaat aactaatgtg atccatttgc ttactaatat ttctcctcga
    12121 gaatactttc gataaaggag atttttcaat gtaccatatt gtgcttccat cgaaatgatc
    12181 gtgcttgcag ctgcaatcat gataaagaca atccaagatg tggcactaaa aagctgagca
    12241 gtcatttcaa ctggatcaat gatcgtcgtg tattttttgg ctagaagtgc tgttcctatg
    12301 agcaaaacaa ctaatagaac agataaaaca gcagttgact ttttcttgat caatttaaat
    12361 aattcttgtt ttacaagcaa tgtcattttt cttcttcccc ctttactgaa tccagaattt
    12421 ccaatagaga agattccaaa tcattcgtca gatgctggac gtctgtcaca tggatatttt
    12481 gtgcagacaa tagctggatc acggttccta ataattcttc gttttctttt aaaagcttga
    12541 ttttatcagg atcttccaaa gtatatccag cttctgtcaa gatcgttcga gcagctagat
    12601 catttgttgt agagataacg atgaaatctt gcgctgtttg gttcaattca gccattgtac
    12661 attgtttgat gatctttcct tgattgatca ggatcagctc atcgaccatt ttttcaagct
    12721 cgctgagtaa gtgactggag atcaagaaag aggtgccctg agtagccaag tcggtaatga
    12781 tttttcgcac atctcttgtt gcttgtggat ccaaaccgtt catcggctca tctaaaataa
    12841 cgatagacgg atggttcagt aaggcaagag caattcccaa tttttgtttc attcccaacg
    12901 agtaggattt cgcttttttg tgaatgtact tttccatctt gagctgattc acgatagtgt
    12961 cgatagcaga tacatcgttg gtttcagaga ataacttcag atgatcatag cctgttaaga
    13021 atggatagat acccgggtat tcgatcaatg ctcctacttg ttccaaccct ttatgactag
    13081 agggagaaat ctcattttca ccaatacaga ttgttccatc tgagtaatgg atcagtccta
    13141 aaatagcttt catgatcgtt gtttttccag cgccattagg acctactaat ccaacgattt
    13201 tgccagggga taagctaaaa ctgacatcgc tgagggcttg tttgtgacca aagttcttgg
    13261 ataattcttg gaccgaaaga cttttcaaaa atattcactc cttttctata gatagtacaa
    13321 gcatacacct gatgagtgga gaagtcgcta ggtcattgga cttatttctt attttttcat
    13381 aaaaaaattg aatattaaat aaaaaggctt attttttctg atcagtactt attccaagtg
    13441 tctagtggcc gctagtaatc ttgatgccaa tgatactgat gagtagcatc cccacaaaga
    13501 accaagtgga aagattcagc ttatcatgaa acaagaccac accaattatg accgaaccaa
    13561 ctgcgccaat ccctgtccag ataggataag agagactcat cggcaaactt ttgattgcct
    13621 ttgacaaaaa gtaaaaacta gcaatcatgc caatcactgt gtaaaaagaa taattgattt
    13681 tagaaaaacc atcactccat ttcatcatcg ttgaccagaa tacttccaaa attcctgcta
    13741 tgattaattc catccatgcc atacttacat tcctccttaa ctataaaaaa atacacaaaa
    13801 agaggaaaat catcccttca aagacctaat ggaatgatca tcctctttat cctacccggt
    13861 ggcagattgt atatcttttt ctgtagtata gcacacctat ccagatatcg gcaatctcat
    13921 actttttagt aaagtgtacc aagcactgac ggatatatcg ttagcggaaa agaagatgaa
    13981 tgctttgcaa tttcatagaa agaagttgtt atttattaat catttaaaaa aaacagtaac
    14041 tagaccttat ttctatatat tatcgggcaa taaattaaaa aaagctttac cttacaataa
    14101 gtaagataat ttttgtgata aaaaaataac gaaaaatatt taaaaatagt gtctatttcg
    14161 tgagaaaaca actatatttt ttatgtgttt tgctttataa ttaaaaaaat attgtcattt
    14221 tatggaggaa aatatatgga aaattatctt agccttttag gcgtcttgat tgttattctc
    14281 gggtttgcat ttaaattaga ctcgatattg atcgtaatgg ttgctttagt tgttacagct
    14341 ttgactggcg gtcttggcat tcaaggaatg ttagaacttt taggtacaag ttttgtaaac
    14401 aatcgcggga tggcgatttt tatcatcatt atgttggcaa caggaacgct tgaaagaaat
    14461 ggtctgaaag aatcagcggc ttccttgatc aagcgattca agaaagtatc tgctggtatg
    14521 attgtagata tttatgggat ctttcgaatg atctttgcgg cttttaacgt gagttttggt
    14581 ggagttgctg gatttgttcg tccaatcatt ttaccgatgg cattggggac catcgaatca
    14641 aaagggttag aagtccatcc taagcatgaa gaagaactaa aaggtatggc ttcagctatg
    14701 gaaaatgtct gctggttctt tggccaagta ctattcatcg gaggagcagg ggcgttgcta
    14761 gtccaatcaa cactgaaaga tctaggatat gacgtaacat tgggacagct tgctttagtg
    14821 gaagttccag tggctatcac ggctttagtt gtggcaagtg tctacttcta tcttaaagaa
    14881 aagaaattag cgaagaaata ttatccagga aaggggcaat aagatggact tttttacaaa
    14941 tcctgatatt ttattaggcg ataaattact ggagatcctt tatatcgtga tgggactcgt
    15001 attgatttac actggagtaa gaaatttaac agataaaacc aatcctcatc gttatgggtc
    15061 agcctttttc tggacggtct taggggtagt tattgcagga ggaagatggc ttccggcaat
    15121 cgtgaacggt ggcttgatct ttgcgatgac cataccagca attgctaaga aagtcagcaa
    15181 aggagaaagc cggcttccat caaaagaata tatggaaaaa atgtcagaca aactaggaat
    15241 gaaaattttt attccagctt tgagtatcgg tgtctttgcg atcttgtttg ctctatttac
    15301 caatttaggt gctttagtcg gcgtgggcgt cggtgttttt gcagccatgc taatcttgat
    15361 gttcttttct cgagataatc gaccaagtac atttttagat gatgcagcag atatgctggg
    15421 cacagtaggg ccgttaagca tgttgccaat gcttttagct tctctaggtg cggtatttac
    15481 aagcgctgga gttgggacag tgatttccaa tgcagtaggt acgatcgttc cagaaggaaa
    15541 tgtgaacatc ggcatcatca tttacgctct tggcatggtg atatttacgg taatcatggg
    15601 gaatgcattt gcggccatca ccgtgatgac ggttgggatc ggtgcaccat tcgtatttag
    15661 tcatggagcg aatccagcgt taataggaat ggttgcattg acttgcggtt tttgtgggac
    15721 cctgctgaca ccgatggctg ctaacttcaa tatcgtgcct gtagcgatgc tggagatgaa
    15781 agacaaatac ggagtgatca aaaaccagtt gtttattgcg ttatttatgc tagttttcca
    15841 aattgcttat atgattctat ttaaataata gaagagaggg gttgtgacag aataattgtc
    15901 gcaacctctt c
//
LOCUS       DAXQKX010000252         9960 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.guided.081, whole genome shotgun sequence.
ACCESSION   DAXQKX010000252 DAXQKX010000000
VERSION     DAXQKX010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9960
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.guided.081"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            complement(121..993)
                     /locus_tag="ACF3MF_003026"
     CDS             complement(121..993)
                     /locus_tag="ACF3MF_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFE3928886.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            1121..1690
                     /locus_tag="ACF3MF_003027"
     CDS             1121..1690
                     /locus_tag="ACF3MF_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DapH/DapD/GlmU-related protein"
                     /protein_id="HFE3928887.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            1757..2494
                     /locus_tag="ACF3MF_003028"
     CDS             1757..2494
                     /locus_tag="ACF3MF_003028"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFE3928888.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            2725..3993
                     /locus_tag="ACF3MF_003029"
     CDS             2725..3993
                     /locus_tag="ACF3MF_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFE3928889.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            4480..4944
                     /locus_tag="ACF3MF_003030"
     CDS             4480..4944
                     /locus_tag="ACF3MF_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFE3928890.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            4928..5557
                     /locus_tag="ACF3MF_003031"
     CDS             4928..5557
                     /locus_tag="ACF3MF_003031"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFE3928891.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            5911..7389
                     /gene="msr(C)"
                     /locus_tag="ACF3MF_003032"
     CDS             5911..7389
                     /gene="msr(C)"
                     /locus_tag="ACF3MF_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HFE3928892.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            7436..7882
                     /locus_tag="ACF3MF_003033"
     CDS             7436..7882
                     /locus_tag="ACF3MF_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HFE3928893.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(8081..8596)
                     /locus_tag="ACF3MF_003034"
     CDS             complement(8081..8596)
                     /locus_tag="ACF3MF_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFE3928894.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            8713..9914
                     /locus_tag="ACF3MF_003035"
                     /pseudo
     CDS             8713..9914
                     /locus_tag="ACF3MF_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
BASE COUNT         3172 a         1748 c         2074 g         2966 t
ORIGIN      
        1 ctggaattat cagaaataaa aggaagaaat aaattaagaa acttatgtta tttaatcgtt
       61 ggatcttttg cttatcttat tcgttgttaa aaagctgaaa gcgaaggaaa aaaactctac
      121 ttaactgtat ttctccgtta ggacatctaa aaatttacga gcagcaggag aaagaggctg
      181 gtcttttttc caaatgagat tcagtgaagc ttgtaatggc ggatcgagtg ggatgaatat
      241 tttttccgtc ccataagtat tgatgatccc atctagagct aatgcaccaa aagtcccgtt
      301 atcgaccatc aaagaagcat tgtacaataa gttatatgtt ccgacgatcg ataactgatc
      361 tatgctgaaa cctagccatt cagctagttg actgtccact gacgtttgcc gggaaatgat
      421 caaaggaaca gttttcagtt cctgcggatg gatgacggtt tgctttgcta aaggatgatt
      481 tcgatgtatc aaaagtcccc aacgatcttg ggctggcagt cgaaatgact ggtatttttg
      541 tttgtttgtc ggttcgatta cgagtccaaa atcaagtaat ccgctatcca gtttgtctat
      601 gatatcatct gcattcccgc tatataaatg aaactggata tcaggatgcg ccttgatcaa
      661 cgaatgaagg ctatcagaaa tgaaagagat tgctttagtt tcgcctccgc caatgtagat
      721 ttctccagag atgattgcgt catttgttaa attgttcgcc gttttttcta ccaacgacaa
      781 gatttctttt ccttttgaat aaagatatcg accagaatcc gtcaactgta tctctcggga
      841 gccccgagtg aaaagtgtca caccaagttc ttcttctaaa tctttcagtt gttttgagag
      901 agtaggttgc gtgatatgca gagattttgc tgctcggctg atattttttt ctctagctac
      961 tgctaaaaaa tacgtcagta tacgaatatc cattttttcc ctcctgtttt taaaaaagca
     1021 taccactaag tatagttaaa aggaatagtt aagtatgttt tataagtatt agacatgata
     1081 agccgtccgt tataaagtaa ggataaaagg agggagcaaa atgacaagcc tcatcgaaaa
     1141 acaaatcgtc aataaagaga ttcgagtaac ggatccgctc tttgaagtga tccatcagat
     1201 ccaagctgaa aacgaagagc ctttagcagc gctgaatact gggtaccatg aaccagcaga
     1261 tatccgcaaa cggctagaaa atatcattag tgacaaagta gatgatacgg tgactgttct
     1321 gctgcctttt tatacagatt tcggcaaaca tattagtata gggaaaaatg tctttatcaa
     1381 tcgtcaagtg atgttcgttg acttaggtgg catctgttta gaagattcag tattgattgg
     1441 tcctcgtgtc aacctcatca cggtgaacca tctaaccgat ccaaaagaac gaagaggctt
     1501 gtcagtaaag ccaatccaca tcaagaaaaa tgcttggatc ggagcaggag caactattct
     1561 gccaggcgta acgattggcg agaatgccat tgttgcagcg aatgcaactg ttacgaaaga
     1621 tgtcccagac aataccatcg ttgcaggaat ccctgccaaa atcgtcaaac ctgtcgaacg
     1681 gattatttga acagtaagat gaaataagag atagtgagta taagcaagag atttttcaaa
     1741 acaggaggag aatagaatga atgatttatc agaaaaagtg attgtcatca tgggcgcttc
     1801 aagcggaatc ggtgaagcaa caacgaagct attagcagaa aaaggggcta aactagttat
     1861 agctgcacgc cgagaagatc gcctaaaagc aataaaagaa tctttaccag aagctgagct
     1921 atatattcaa acagcagatg taagagattt tgcacaagtc caagcagtta tcgatttagc
     1981 gatggaaaag ttcggtcgaa tcgatgtatt gtacaataat gcaggaatca tgccaaccgc
     2041 tccattagtt gaaggtcacc gtgatgaatg gcaaaatatg cttgatatca acatcatggg
     2101 tgtgttaaat ggaatttccg ccgtacttcc aatcatggaa aaacaaaaat ctgggcatat
     2161 catttcaact gattctgtgg cgggacatgt tgtttatcct gattccgccg tttattgcgg
     2221 aacaaaattt gctgtccgtg caatcatgga aggattacgt caagagcaac ggcaaaataa
     2281 catcaaatct acgatcatct ctccaggagc tgttcaaact gaattatatc aaaccatcag
     2341 cgacaaaaag gctgctcttg aacttcatga agcgcaaaaa gaatggggat tgacctccga
     2401 agatatagct tctgctgtag catttgcgat agaaacgcca gaccggatgt ctgtcagtaa
     2461 catgattatc cgtccgacga cacaggaagt ataatccata acggataata tccaaagaga
     2521 attacttgtt aaatagttat tcaaacgacc atcaatttaa ggcgtgaatg gagaagaata
     2581 ttcttcattt acgtcttttt atgtagaaaa agcaaattta tcaaaaagaa acaaatgtta
     2641 tttaaatatg gacattgact tgcttttact tttttagtta cactgttatt taggaaaagt
     2701 ttcataattc aaaggagaaa aaagatgaaa gcaaagaatt tattatttag cgttattctt
     2761 ttaggaaatc tagcagttgc caacacaaca gtgctagctg aagaatcgac agaaactgtc
     2821 gcaactcaga catcgagttc ttcagaaaca ggaattgaaa acgatacaga gagtactttg
     2881 cagtcagcta ctgtctcaga aaatacaatt tcaaccgaag aaccaacaac tgaaacaaca
     2941 gaacaaacac aaaccgaaga cagtacatca gcagaagctc agaacaatcc agagaatgca
     3001 gaagaaatca cgaaccaatt gacagatggg caaacattga cacataccca tcaagcagat
     3061 ttgtctgaat tcgaaaacta tactggctat gctttttatg ctcgctcatc tgctaattct
     3121 caacaagcgt tcattgatag tattgcctca actgcacaaa gtttggcaag tgccaatgac
     3181 ttatatgcat cagtcatgat tgctcaagcc atcgttgaaa gtggctgggg gaacagtact
     3241 ttggcttctg cccctaatta caatctattt gggattaaag gaagctataa tggccaatct
     3301 gttacgatgc ctacttcgga atatgtgaat gggcaatgga ttacggtgaa tgccgctttt
     3361 agaaaatatc cttcgtacaa agaatcattg caagataacg taacggtatt gaagacgact
     3421 tcttttcagc caggcgttta ctactattcc ggtgcatgga aaagcaatac gaactcttac
     3481 aaagatgcta cggcttggct aacaggtcgt tatgccactg cgcctaatta tggttctaca
     3541 ttgaacaatg taatcgaaac ctataatctg acacagtatg atacagcacc aacttcaact
     3601 tctccgatgt atcgtctgta taaccgtcat acaggagaac atttatatac attgaatgcc
     3661 ggagaaaaaa attatctgcc aactgtaggc tgggaatatg aagggattgc ttggcaagca
     3721 ccaaacagcg gacaacctgt ctaccgttta tacaatcctt acagtggaga ccatcattac
     3781 acaatggcac aatctgagat caactcttta acaaaaatcg gttggcgtta tgaaggtcta
     3841 agtttttatt ctggtggttc caagccaatt tatcgactat ttaatccaaa tgaaaaaact
     3901 ggtacccatc actatacctt gagtgctaag gaaagagatt ggctaacacc gatgggctgg
     3961 agatatgaag gaataggatt ttatggttat taaaaagagg tagtgaaaaa gctgccctgc
     4021 atcaagtagt aagaacagcc aaacaaaaac agattttcat gttttttgtt tggttgaact
     4081 tattaccgca gatgcaagtt tttgaacacc gtttactcaa aaaaggttgt gacaacatct
     4141 tgtcataact tttttattac tgtttaagca tactgatcca atttctaata ttcgacggga
     4201 ttcttgcaaa aggcgatttc ggaaattttt ggcggtgtaa aattttctac tgcagaagag
     4261 ctatcttcta tagtttgata agaatcaata atcttggttt tagcgttgtg ctttctttat
     4321 cattttttcc gttcattcta caaaaaattt cttttctcta tacttttcta ttgagagcgt
     4381 tttttttatt acacagctga ttctttgact tttttctttt tttattctat tattgacaag
     4441 tcaatcgttg acgagtcaat tattagaaag gaggaaatta tgtctttaga agagattagt
     4501 caccttttat atcaaatcaa attagccgat caaaaaatcg tccagatctt tgaagaaaat
     4561 atcggtataa gtcttactag atacgagatc atgatgagac tgaaagaaga aaatccattg
     4621 ctacaaagca gtttgcaaga aaagttgcag attgatcaag gagcagttac tcgtcatctg
     4681 aaggtattgg aagcaaatgg ctatgtttcg cgtcagagaa atcctcagaa caaccgggaa
     4741 gtgtatgtag cgctaacaga aaaagcccag aagaaaatcg agcattgtga aatggaccat
     4801 aaagatacag gttccgtgct atccccggct ttcagcgatg tagaaatgaa acaatttcta
     4861 acacttttag ataaattgaa tacccaactt tgcaatataa caacagaaac gaaagaggtt
     4921 aataataatg gaacaaaaaa atgatttttc aacaattatg actggtagaa gatccgttcg
     4981 cgtatatgat gaaacataca aaatcccaca cgaagaaatg ctggaaatga tcaaagaagc
     5041 gacgactgca ccttcttctg tcaatatgca accatggcgc tttgtggtcg ctgaaagcga
     5101 ggaagcaaaa gaaatcttgc gtcctttgat ccgtttcaat acgagacaaa atgatacttc
     5161 ttctgcaatg gtcatgattt ttggcgatat gcaatgttac gaatatggcg aagaaatcta
     5221 taaccaagct tacgaatcag ggaagatgcc aaaagaagtc agagatcaac aattagctgc
     5281 gatcattcct tattacaaga gtttttcaag agaagaaatg aacgatgtag tcaaagtcga
     5341 ttctagctta gcggctatgc aattcatgtt agttgcgcgt gatcatggct atgaaacaaa
     5401 tccaattggt ggattcgaag cagatcagtt ggcagaggca tttggtttgg ataaagaccg
     5461 ttatgttcca gttattattt tatcaatagg aaaagcggta gaagaaggtt acgagtctgt
     5521 tcgtttagca ccagaaaaga tcactacgtt cgaataaaag gttttcagtt actattcagt
     5581 agctattgct ttttttgaat cgtgtgtggt aacctaataa aaaaggaggt cggaaaaatg
     5641 actgcatcga tgaaattacg tttcgaactt ttgaataaca actaaataaa ttcaaaagac
     5701 atgtataaac aacaatttca tggatggagt atgtccattt tttcgaacga cagtagaata
     5761 ggtgaaagct atgacagatt tggtgattta gtcatagtta tttcgttcag agtaggaaaa
     5821 gatgtgatgc agtttttttg caaacagatt tttctgctct tttttagtat cgataattgt
     5881 tgttttacat gaaataggag tgtaaaacat atggaaaatt tagcagtaaa tataacaaat
     5941 ctacaagtca gctttggcaa ccagctagaa ctatctattg attctcttcg tgtctatcag
     6001 caagatcgta tagggatcat aggagaaaat ggtgtcggta aatcgacttt gctcaaacta
     6061 atagccggtg aactttttcc cgatcatggg aaaatccaaa cagagatcac cttcaactac
     6121 ctgcctcaat taacctatct cgctgaagca aaggacctaa atttggaatt agccagtcat
     6181 ttccagttaa gactggaaga aacttcagag cggaaatgga gcggagggga agaacgaaag
     6241 atcgagttga tacgtcttct ttcttcttat gaacaaggga tgcttctaga cgagccaaca
     6301 acccatctag atagaaaaag tattgatcga ctgattgaag agcttcgtta ttattatggt
     6361 acgctggttt ttgttagtca tgatcgctat tttctagatg agctagcatc gaaaatctgg
     6421 gaagtaaaag acggagaaat ccgagagttt tcggggaatt atagtgccta tctcactcaa
     6481 aaggaattgg agaaaaagac tcagctacga gaagcagagt cgatcatgaa agagaaaaaa
     6541 cgattggaaa aatcgatcca agaaaagaaa aaacaagcgg aaaagttgga aaaagtgtcc
     6601 agtaaaaaga aaaagcaaca aatcagaccg gatcggttgt cttcctctaa acaaaaagac
     6661 agtgtacaaa aagccatcca aaagaatgcg aaaacattag agagaagact ccaaaaaata
     6721 ggagaaacaa ccaagccgca gcagatgaaa caaatccgtt ttccagtacc aaaatctctt
     6781 gaactccaca gccgctatcc catcatggga caaaatgtcc aattggaaag aagtgggaga
     6841 acattactgg taaatggtga ttttcagttt tctttaggta aaaaaatcgc gattgtcggt
     6901 gaaaatggtt caggtaagac aaccttatta gaacatatcc gcaaacaagg agaaggaatc
     6961 cttctctctc cgaaagtaag ctttcaagta tatcagcaaa agggttatca aatgacatct
     7021 gaagaatcca tcattcgttt tgtcatgaga caaacagagt tttcagaatc gcttgtccgt
     7081 agtttgctga atcacttagg gtttgctcag gaaactttga cgaaaccgtt atgtacatta
     7141 agtgggggag aagcgacccg tctgacgatt gctttgcttt ttactaagcc aagtaatgtg
     7201 ttgctgttag atgaaccgac taattttatt gatatggcaa cgatcgaagc tttagagaag
     7261 ctaatgcaaa tatatccggg aacgattttg tttacttctc atgattctta ctttgtcgag
     7321 cgtacggctg atgaagttta tgaaataaaa gggcagaaaa taaaaaaagt acttacgaga
     7381 aatttttaaa tgtgctacga tgattttcgt gacaaattta aaggagtggt acagattgcc
     7441 tacaaataaa aaagaaggaa taatttttac aacaatgatg tgttttttga tggtcttggg
     7501 gatgagcgcg tataatttat ggctgcatca agatcttcat ttatcaagtt tgttgattgg
     7561 tctagtgcct ggattcgtgg tggctttcat tttggatgtc ttcatcatcg gtgtgctggc
     7621 gaaaaaaatt gcctttaaac taccagtaaa tccagaaagc aaggtccaaa tgatcttaac
     7681 tatttcatgc ttgatggttt taggaatggt gacatgtatg tctttattcg gtgtgatcat
     7741 ggaacaagga atacctgatc aattattctc tgcttatatg aatgcttgga aaatgaatgt
     7801 gattgccgct ttaccgttgc agttgatcat cgttggcccg ctttcaagaa gtgtgctaaa
     7861 agcaattcaa agtaatgaat gatggaacac tgttatttga aaaaaggcct tggcatgctt
     7921 tttgtcatag tctcttgaat gcagttctag aaaaatagtg atccgaacga taggttttgg
     7981 cctgtcgttc ggatcgcttt ttcttttcca actgtattgc tcttttattg aagataattt
     8041 gctcttcaat agatatttct agaaaggttc tgtttatccc ttactcaaaa aactgctgca
     8101 tttgttctct tacttgctga caccattgga gttcctgctg acaaagcata attctgcgct
     8161 ggatcacaac ataacgtcca aattcttgtt tcttgtctag cgagaggtca ttcaattttt
     8221 tttgattttt ttgcatgatt ttgttcagct gttgttctct agtgaatagc agtccagtag
     8281 ctgttgtttt atcgagcgtc gaaaaagcat agatttttgc tagaaattca tctttttgcg
     8341 taggagcggg agtttcctct ttgatccatt cctctacaag agcacgtcct tcatcagtca
     8401 agtggtagat ctttttttga gagtgctcgt ctttgtccaa aacggtcaca taaccctgct
     8461 ggtctaactt ggcaagcgtt gtatagatct gactgtgatg ggcttcccaa aaaattgtga
     8521 tcagctgctt caattcatac ccagaacgtg gtttggataa aagcacgcat aataatatat
     8581 aggctaaagt attcataaaa atcctacctc tcgtcttatt ttctttatta tatcacagta
     8641 aagtttccac gttttacatg tgcatattta catgtaaaat aaatcatgta tgatgctaat
     8701 agagagaaag ggatggaaat attggagaat caaatagata tacaagaaca aacaaatgaa
     8761 gaaacaaagg ggaaaagttc agcgctagtt gtagcagcta cctgtatgat cgcttttatg
     8821 ggagtgggtc tagtagaccc aatcttaaaa acgattgctg cacagttaaa cgctacgcca
     8881 gctgaaacga ccctgttatt tactagttac atgttagtca ctggtgtggt gatgctattt
     8941 acaggtttct tatctagtcg gatcggtttg aaaaaacatt gatgacagga ttgtttatca
     9001 tcgttgtatt cgctggtctt ggcggattat ctgggaatat cggaatgctg attgggttac
     9061 gtgccggctg gggtgtcggg aatgctttat ttgtctctac tgctttagca acgatcgtca
     9121 gtattttagt tggtaacaca gaaaaagcaa tcatgatgta tgaagcagca cttggctgcg
     9181 gaatggctgt tggccctcta gtcggtgggg tcttgggcag tggttcatgg cgttatccat
     9241 tttttggggt agcatttttg atgttttgcg gttttatagc cctagcggta cttttacctg
     9301 aaactgagaa accaaagaga aaagtaggcc tttgggaagg tgtcaaagcg ttaagcaatc
     9361 ataaacttcg ttcagttgga ctaatcgcat tgttatataa tttcggattc tttactttac
     9421 ttgcgtatgc gccattttta ttgattggct attctgaatt agaagtcggt tttgtatttt
     9481 ttggctgggg tgtgcttctg gctattgctt cgattttcgt tgcaccggct cttgagcgga
     9541 agtttacgac ttatcggaca attttagcag catttgtctt attcattatt tgtttgctgt
     9601 tattaggagc tggaacttct atgccagtcc ttgtaccgat cagcattgtg ttagcaggat
     9661 ttttccaagg aattatcaat acactgttga cgacgattgc tatggaaata ccaggtctgc
     9721 aacgaaacgt tgcttcgtcc agctatagtt ttgtccgctt tttcggtgga gctttagcac
     9781 catttattgc aggtgtgatt ggtgaacata ttggtgaaag ctatgcgttt tattttgcag
     9841 gtgccattgt tcttatcagt gtatgttgta tcatttatca ccgtaattat tttgctacaa
     9901 atgaagaaga ataagaaatc agaggttgtg aaaaagctgt cctgcatcaa gtcataagaa
//
LOCUS       DAXQKX010000253         5037 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.guided.113, whole genome shotgun sequence.
ACCESSION   DAXQKX010000253 DAXQKX010000000
VERSION     DAXQKX010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5037)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5037)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5037
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.guided.113"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            22..1941
                     /gene="tet(M)"
                     /locus_tag="ACF3MF_003036"
     CDS             22..1941
                     /gene="tet(M)"
                     /locus_tag="ACF3MF_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HFE3928895.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIV
                     NTQLKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRL
                     NSRIDKVRYMFNKIT"
     gene            2039..2227
                     /locus_tag="ACF3MF_003037"
     CDS             2039..2227
                     /locus_tag="ACF3MF_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HFE3928896.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(2285..2638)
                     /locus_tag="ACF3MF_003038"
     CDS             complement(2285..2638)
                     /locus_tag="ACF3MF_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3928897.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            3169..3591
                     /locus_tag="ACF3MF_003039"
     CDS             3169..3591
                     /locus_tag="ACF3MF_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFE3928898.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            3588..3818
                     /locus_tag="ACF3MF_003040"
     CDS             3588..3818
                     /locus_tag="ACF3MF_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3928899.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            4316..4516
                     /locus_tag="ACF3MF_003041"
     CDS             4316..4516
                     /locus_tag="ACF3MF_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000633907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HFE3928900.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            4543..>5037
                     /locus_tag="ACF3MF_003042"
     CDS             4543..>5037
                     /locus_tag="ACF3MF_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Arm DNA-binding domain-containing protein"
                     /protein_id="HFE3928901.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQK"
BASE COUNT         1726 a          807 c          965 g         1539 t
ORIGIN      
        1 ttttgaatgg aggaaaatca catgaaaatt attaatattg gagttttagc tcatgttgat
       61 gcaggaaaaa ctaccttaac agaaagctta ttatataaca gtggagcgat tacagaatta
      121 ggaagcgtgg acaaaggtac aacgaggacg gataatacgc ttttagaacg tcagagagga
      181 attacaattc agacaggaat aacctctttt cagtgggaaa atacgaaggt gaacatcata
      241 gacacgccag gacatatgga tttcttagca gaagtatatc gttcattatc agttttagat
      301 ggggcaattc tactgatttc tgcaaaagat ggcgtacaag cacaaactcg tatattattt
      361 catgcactta ggaaaatggg gattcccaca atctttttta tcaataagat tgaccaaaat
      421 ggaattgatt tatcaacggt ttatcaggat attaaagaga aactttctgc cgaaattgta
      481 atcaaacaga aggtagaact gtatcctaat atgtgtgtga cgaactttac cgaatctgaa
      541 caatgggata cggtaataga gggaaacgat gaccttttag agaaatatat gtccggtaaa
      601 tcattagaag cattggaact cgaacaagag gaaagcataa gatttcagaa ttgctccttg
      661 taccctgttt atcatggaag cgcaaaaagc aacataggga ttgagcagct tatagaagtg
      721 ataacgaata aattttattc atcaacatac agaaagaagt ctgaactttg cggaaatgtc
      781 ttcaaaattg aatattcgga agaaagacaa cgtcttgcat atgtacgcct ttatggcgga
      841 atcctgcatt tgcgggattc ggttagaata tcggaaaagg aaaaaataaa aattacagaa
      901 atgtatactt caataaatgg tgaattatgt aaaattgata aggcttattc cggggaaatt
      961 gttattttgc aaaatgagtt tttgaagcta aatagtgttc ttggagatac aaagctattg
     1021 ccacagagag agagaattga aaatccgctc cctctgctgc aaacaactgt tgaaccgagc
     1081 aaacctcaac aaagggaaat gttacttgat gcacttttag aaatctccga cagtgacccg
     1141 cttctacaat attatgtgga ttctacgaca catgaaatta tactttcttt cttagggaaa
     1201 gtacaaatgg aagtgattag tgcactgttg caagaaaagt atcatgtgga gatagaacta
     1261 aaagagccta cagtcattta tatggagaga ccgttaaaaa atgcagaata taccattcac
     1321 atcgaagtgc cgccaaatcc tttctgggct tccattggtt tatctgtatc accgcttccg
     1381 ttgggaagtg gaatgcagta tgagagctcg gtttctcttg gatacttaaa tcaatcattt
     1441 caaaatgcag ttatggaagg gatacgctat ggttgcgaac aaggattata tggttggaat
     1501 gtgacggatt gtaaaatctg ttttaagtac ggtttatact atagccctgt tagtactcca
     1561 gcagattttc ggatgcttac tcctattgta ctggagcaag cctttagaaa agctggaaca
     1621 gaattgttag agccatatct tagttttaaa gtttatgcac cacaggaata tctttcacgg
     1681 gcatataacg atgctcccaa atattgtgca aatatcgtaa atactcaact gaaaaataat
     1741 gaggtcatta ttattggaga aattcctgct cgatgtattc aagattatcg caatgattta
     1801 acttttttta caaatgggct tagtgtttgt ttagcagagc taaaaggata tcaggttacc
     1861 actggcgaac ctgtttgcca gacccgtcgt ctaaatagtc ggatagataa agtaagatat
     1921 atgttcaata aaataactta gtgcgtttta tgttgttata taaatatggt ttcttattaa
     1981 ataagatgaa atattcttta atatagattt gaattaaagt ggaaaggagg agattgttat
     2041 tataaactac aagtggatat tgtgtcctat ttgtggaaat aaaacaagac tacgaatacg
     2101 agtggatact atacttaaaa atttcccttt atactgcccc aaatgtaaga acgaaacttt
     2161 aattaatgtt caaaaaatga atataataac aatcaaagag ccagacgcca agacgcagag
     2221 ccgataattt gagaaatgaa actctcatct tatcggctct ttttgtttat ctgaatttta
     2281 ctgactagcc ttcaatattt cttgcttcat tgataccttt tgctagtgct tccattaagg
     2341 atagttcttt gtctgtaaag ctatccatgt atttttctac ctgtaacctt cgagtgcttt
     2401 taatcaaatt atctgtaggt aagaaaaatt catcaataga tacatggagt aatgatacaa
     2461 gatcatacag cacttgtgta cttgggtgtt gtcctttgtt ttctatattt gttaaataac
     2521 gtgggtcaat ttcaatcatt gttcccactt gttcacgagt gagaccccgt ttcattcgag
     2581 cctctttaat cgctaaacca acggctctaa aatcgtattt atcttctttt ttacgcatac
     2641 taaatcacct ctatacattt tactgttcct atataaccat aaacaggtat agaaaaacat
     2701 gttatatagt ttatgagttc ctatagaaca ctgtggaatt tattaatgcg atgaatccaa
     2761 tttcaaatag aaaggtcgct gattttattt acctatacaa ctttataaaa tttagtcata
     2821 ctcctagaaa gtagataaaa ttggcgactt aatggaggga aaagtcgcca tgagaaagat
     2881 aatctgtcat ctagttctct taattaagtt cttatcaaaa aaacttatcc acctgtactg
     2941 gatagatatg accatcaatg tggttttgca gattacatag atagaaaaat caaagcatat
     3001 gaacagagaa aacaatctgt ttatgtgctt ttttggtcac ttaataaata tcttttagga
     3061 tttctcttca tttatgcaac aaatcccccg ttcgtgtcgg ggtttagtat gaagggagat
     3121 aaagaagcac atgccactcc ctttcacgac agaaaggggg tgaaaagcat gaaaccatct
     3181 tcttttcaag aaaccataga aaatcagttt gactatatct gcaaacaagt tattgaagat
     3241 gaacgaaaag attacttcaa acatctagac agactatcag caaaagaagt ctcgttttct
     3301 gatatagata actaccttgt caactctttt tctactgttg atacgtacgt cactgatttc
     3361 caactattta aattatttgg attaagaatc aatgttgaaa gtgatttatt aagtgaagcc
     3421 ctgcgtcatc tttcagagaa aaaacggaac attattttac ttcattactt tatggatatg
     3481 agtgatgtgg agattgcgga gttactaaat ttgaatcgtt cgactgttta tcgtcatcga
     3541 ataagtggac tagccatgat taaagaattc atgaaggagt gtaaagaatg aaaacagctt
     3601 atccaagggt tcccttcccc ctcattgtaa aggcgacaga tggcgacgtg gaagcaatta
     3661 atcagattgt taaacattat cgagggtata cctcaaaacg ttcattacgt cgcatgacag
     3721 acgaatatgg aaattctcat atggttattg atgaaaccct acgtggcaga atggaaacga
     3781 aactcatctc taagatttta tcgttcgaaa ttaaatagtc ccattttttc gtggaagcgt
     3841 gtcgaatcgt atccacgctt cccgatttgg gaggtttgtt attccatcaa agcatattgt
     3901 gtgttcagta ggttttgata ggctaacaag ccaaacgttc tttgacaacc aaataaaggc
     3961 aatcgaatac gtttcggtaa gaaaagagct gatgaactaa cacgccatga cctacaaaat
     4021 tagtgagcga ttcatgttag taattcgaaa gtaatcttta gcaggattgc tgccatgact
     4081 ttcttatcgt gataatgata ctcccgtata gccatagtcc gagcgttaga agcgtcacag
     4141 gcaatgggta cggctacatg agaaccatgc agaagtgaaa ttcctgtgag ctttgctaga
     4201 gctgttcgat tgctaagata ttcttctctt gtcagtgtat tattataaaa ctatttgata
     4261 taattatagg tgaatattgg agttttccta gcctataatt gggaaaggag taataatgat
     4321 aacggtcaca aaaaaggatt tagttgagct aggatatgga acttcttttt cagcagacat
     4381 cataaaaaaa gcaaaagaat tgatgattac aaaagggcat atctactatc aatctcgaaa
     4441 gctagataga gtccctcgtg aagctgttga agaaattcta ggaattcggt tttcaaatga
     4501 aaacaggtct gagtagtttt tgcacagtaa ggagtaaaaa ctatggttaa agacccaata
     4561 aaaaaagcaa agaatggaac ctattatttt cgtgcaaatc taggttatga ttctaaaggg
     4621 aaaaaaattc aaaaatatcg tagtggattc actactaaaa aagaagcaag agaagaatat
     4681 tcgaaactgc tattgatgaa accagaagaa ttaagtgaga ataaggataa aatgacgttt
     4741 aaacattata tctttgaaat tttccttcca tggtataaga cacaggtaaa gctcagaaca
     4801 tatgaaaatc gcttaccaac tattaagaag catttctctt attttgataa aatggctgtt
     4861 tccgatattg agcctattga tgtgcaaaat tggcaactaa aattatcaaa gaagtgtaag
     4921 tcttcttatg taagagctgt tcaaggacta ttttcagttg ctatggatcg agcaattgtc
     4981 cttgggataa ccaccacaaa tccatctaag attattggca atgtgaaaaa gcaaaag
//
LOCUS       DAXQKX010000254         5037 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.guided.114, whole genome shotgun sequence.
ACCESSION   DAXQKX010000254 DAXQKX010000000
VERSION     DAXQKX010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5037)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5037)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5037
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.guided.114"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            22..1941
                     /gene="tet(M)"
                     /locus_tag="ACF3MF_003043"
     CDS             22..1941
                     /gene="tet(M)"
                     /locus_tag="ACF3MF_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HFE3928902.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIV
                     NTQLKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRL
                     NSRIDKVRYMFNKIT"
     gene            2039..2227
                     /locus_tag="ACF3MF_003044"
     CDS             2039..2227
                     /locus_tag="ACF3MF_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HFE3928903.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(2285..2638)
                     /locus_tag="ACF3MF_003045"
     CDS             complement(2285..2638)
                     /locus_tag="ACF3MF_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3928904.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            3169..3591
                     /locus_tag="ACF3MF_003046"
     CDS             3169..3591
                     /locus_tag="ACF3MF_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFE3928905.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            3588..3818
                     /locus_tag="ACF3MF_003047"
     CDS             3588..3818
                     /locus_tag="ACF3MF_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3928906.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            4316..4516
                     /locus_tag="ACF3MF_003048"
     CDS             4316..4516
                     /locus_tag="ACF3MF_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000633907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HFE3928907.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            4543..>5037
                     /locus_tag="ACF3MF_003049"
     CDS             4543..>5037
                     /locus_tag="ACF3MF_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Arm DNA-binding domain-containing protein"
                     /protein_id="HFE3928908.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQK"
BASE COUNT         1725 a          807 c          966 g         1539 t
ORIGIN      
        1 ttttgaatgg aggaaaatca catgaaaatt attaatattg gagttttagc tcatgttgat
       61 gcgggaaaaa ctaccttaac agaaagctta ttatataaca gtggagcgat tacagaatta
      121 ggaagcgtgg acaaaggtac aacgaggacg gataatacgc ttttagaacg tcagagagga
      181 attacaattc agacaggaat aacctctttt cagtgggaaa atacgaaggt gaacatcata
      241 gacacgccag gacatatgga tttcttagca gaagtatatc gttcattatc agttttagat
      301 ggggcaattc tactgatttc tgcaaaagat ggcgtacaag cacaaactcg tatattattt
      361 catgcactta ggaaaatggg gattcccaca atctttttta tcaataagat tgaccaaaat
      421 ggaattgatt tatcaacggt ttatcaggat attaaagaga aactttctgc cgaaattgta
      481 atcaaacaga aggtagaact gtatcctaat atgtgtgtga cgaactttac cgaatctgaa
      541 caatgggata cggtaataga gggaaacgat gaccttttag agaaatatat gtccggtaaa
      601 tcattagaag cattggaact cgaacaagag gaaagcataa gatttcagaa ttgctccttg
      661 taccctgttt atcatggaag cgcaaaaagc aacataggga ttgagcagct tatagaagtg
      721 ataacgaata aattttattc atcaacatac agaaagaagt ctgaactttg cggaaatgtc
      781 ttcaaaattg aatattcgga agaaagacaa cgtcttgcat atgtacgcct ttatggcgga
      841 atcctgcatt tgcgggattc ggttagaata tcggaaaagg aaaaaataaa aattacagaa
      901 atgtatactt caataaatgg tgaattatgt aaaattgata aggcttattc cggggaaatt
      961 gttattttgc aaaatgagtt tttgaagcta aatagtgttc ttggagatac aaagctattg
     1021 ccacagagag agagaattga aaatccgctc cctctgctgc aaacaactgt tgaaccgagc
     1081 aaacctcaac aaagggaaat gttacttgat gcacttttag aaatctccga cagtgacccg
     1141 cttctacaat attatgtgga ttctacgaca catgaaatta tactttcttt cttagggaaa
     1201 gtacaaatgg aagtgattag tgcactgttg caagaaaagt atcatgtgga gatagaacta
     1261 aaagagccta cagtcattta tatggagaga ccgttaaaaa atgcagaata taccattcac
     1321 atcgaagtgc cgccaaatcc tttctgggct tccattggtt tatctgtatc accgcttccg
     1381 ttgggaagtg gaatgcagta tgagagctcg gtttctcttg gatacttaaa tcaatcattt
     1441 caaaatgcag ttatggaagg gatacgctat ggttgcgaac aaggattata tggttggaat
     1501 gtgacggatt gtaaaatctg ttttaagtac ggtttatact atagccctgt tagtactcca
     1561 gcagattttc ggatgcttac tcctattgta ctggagcaag cctttagaaa agctggaaca
     1621 gaattgttag agccatatct tagttttaaa gtttatgcac cacaggaata tctttcacgg
     1681 gcatataacg atgctcccaa atattgtgca aatatcgtaa atactcaact gaaaaataat
     1741 gaggtcatta ttattggaga aattcctgct cgatgtattc aagattatcg caatgattta
     1801 acttttttta caaatgggct tagtgtttgt ttagcagagc taaaaggata tcaggttacc
     1861 actggcgaac ctgtttgcca gacccgtcgt ctaaatagtc ggatagataa agtaagatat
     1921 atgttcaata aaataactta gtgcgtttta tgttgttata taaatatggt ttcttattaa
     1981 ataagatgaa atattcttta atatagattt gaattaaagt ggaaaggagg agattgttat
     2041 tataaactac aagtggatat tgtgtcctat ttgtggaaat aaaacaagac tacgaatacg
     2101 agtggatact atacttaaaa atttcccttt atactgcccc aaatgtaaga acgaaacttt
     2161 aattaatgtt caaaaaatga atataataac aatcaaagag ccagacgcca agacgcagag
     2221 ccgataattt gagaaatgaa actctcatct tatcggctct ttttgtttat ctgaatttta
     2281 ctgactagcc ttcaatattt cttgcttcat tgataccttt tgctagtgct tccattaagg
     2341 atagttcttt gtctgtaaag ctatccatgt atttttctac ctgtaacctt cgagtgcttt
     2401 taatcaaatt atctgtaggt aagaaaaatt catcaataga tacatggagt aatgatacaa
     2461 gatcatacag cacttgtgta cttgggtgtt gtcctttgtt ttctatattt gttaaataac
     2521 gtgggtcaat ttcaatcatt gttcccactt gttcacgagt gagaccccgt ttcattcgag
     2581 cctctttaat cgctaaacca acggctctaa aatcgtattt atcttctttt ttacgcatac
     2641 taaatcacct ctatacattt tactgttcct atataaccat aaacaggtat agaaaaacat
     2701 gttatatagt ttatgagttc ctatagaaca ctgtggaatt tattaatgcg atgaatccaa
     2761 tttcaaatag aaaggtcgct gattttattt acctatacaa ctttataaaa tttagtcata
     2821 ctcctagaaa gtagataaaa ttggcgactt aatggaggga aaagtcgcca tgagaaagat
     2881 aatctgtcat ctagttctct taattaagtt cttatcaaaa aaacttatcc acctgtactg
     2941 gatagatatg accatcaatg tggttttgca gattacatag atagaaaaat caaagcatat
     3001 gaacagagaa aacaatctgt ttatgtgctt ttttggtcac ttaataaata tcttttagga
     3061 tttctcttca tttatgcaac aaatcccccg ttcgtgtcgg ggtttagtat gaagggagat
     3121 aaagaagcac atgccactcc ctttcacgac agaaaggggg tgaaaagcat gaaaccatct
     3181 tcttttcaag aaaccataga aaatcagttt gactatatct gcaaacaagt tattgaagat
     3241 gaacgaaaag attacttcaa acatctagac agactatcag caaaagaagt ctcgttttct
     3301 gatatagata actaccttgt caactctttt tctactgttg atacgtacgt cactgatttc
     3361 caactattta aattatttgg attaagaatc aatgttgaaa gtgatttatt aagtgaagcc
     3421 ctgcgtcatc tttcagagaa aaaacggaac attattttac ttcattactt tatggatatg
     3481 agtgatgtgg agattgcgga gttactaaat ttgaatcgtt cgactgttta tcgtcatcga
     3541 ataagtggac tagccatgat taaagaattc atgaaggagt gtaaagaatg aaaacagctt
     3601 atccaagggt tcccttcccc ctcattgtaa aggcgacaga tggcgacgtg gaagcaatta
     3661 atcagattgt taaacattat cgagggtata cctcaaaacg ttcattacgt cgcatgacag
     3721 acgaatatgg aaattctcat atggttattg atgaaaccct acgtggcaga atggaaacga
     3781 aactcatctc taagatttta tcgttcgaaa ttaaatagtc ccattttttc gtggaagcgt
     3841 gtcgaatcgt atccacgctt cccgatttgg gaggtttgtt attccatcaa agcatattgt
     3901 gtgttcagta ggttttgata ggctaacaag ccaaacgttc tttgacaacc aaataaaggc
     3961 aatcgaatac gtttcggtaa gaaaagagct gatgaactaa cacgccatga cctacaaaat
     4021 tagtgagcga ttcatgttag taattcgaaa gtaatcttta gcaggattgc tgccatgact
     4081 ttcttatcgt gataatgata ctcccgtata gccatagtcc gagcgttaga agcgtcacag
     4141 gcaatgggta cggctacatg agaaccatgc agaagtgaaa ttcctgtgag ctttgctaga
     4201 gctgttcgat tgctaagata ttcttctctt gtcagtgtat tattataaaa ctatttgata
     4261 taattatagg tgaatattgg agttttccta gcctataatt gggaaaggag taataatgat
     4321 aacggtcaca aaaaaggatt tagttgagct aggatatgga acttcttttt cagcagacat
     4381 cataaaaaaa gcaaaagaat tgatgattac aaaagggcat atctactatc aatctcgaaa
     4441 gctagataga gtccctcgtg aagctgttga agaaattcta ggaattcggt tttcaaatga
     4501 aaacaggtct gagtagtttt tgcacagtaa ggagtaaaaa ctatggttaa agacccaata
     4561 aaaaaagcaa agaatggaac ctattatttt cgtgcaaatc taggttatga ttctaaaggg
     4621 aaaaaaattc aaaaatatcg tagtggattc actactaaaa aagaagcaag agaagaatat
     4681 tcgaaactgc tattgatgaa accagaagaa ttaagtgaga ataaggataa aatgacgttt
     4741 aaacattata tctttgaaat tttccttcca tggtataaga cacaggtaaa gctcagaaca
     4801 tatgaaaatc gcttaccaac tattaagaag catttctctt attttgataa aatggctgtt
     4861 tccgatattg agcctattga tgtgcaaaat tggcaactaa aattatcaaa gaagtgtaag
     4921 tcttcttatg taagagctgt tcaaggacta ttttcagttg ctatggatcg agcaattgtc
     4981 cttgggataa ccaccacaaa tccatctaag attattggca atgtgaaaaa gcaaaag
//
LOCUS       DAXQKX010000255         4224 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.guided.120, whole genome shotgun sequence.
ACCESSION   DAXQKX010000255 DAXQKX010000000
VERSION     DAXQKX010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4224
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.guided.120"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..1128
                     /locus_tag="ACF3MF_003050"
     CDS             <1..1128
                     /locus_tag="ACF3MF_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetM/TetW/TetO/TetS family tetracycline
                     resistance ribosomal protection protein"
                     /protein_id="HFE3928909.1"
                     /translation="LAYIRLYSGVLHLRDSVRVSEKEKIKVTEMYTSINGELCKIDRA
                     YSGEIVILQNEFLKLNSVLGDTKLLPQRKKIENPHPLLQTTVEPSKPEQREMLLDALL
                     EISDSDPLLRYYVDSTTHEIILSFLGKVQMEVISALLQEKYHVEIELKEPTVIYMERP
                     LKNAEYTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSFQNAVMEGIR
                     YGCEQGLYGWNVTDCKICFKYGLYYSPVSTPADFRMLTPIVLEQAFRKAGTELLEPYL
                     SFKVYAPQEYLSRAYNDAPKYCANIVNTQLKNNEVIIIGEIPARCIQDYRNDLTFFTN
                     GLSVCLAELKGYQVTTGEPVCQTRRLNSRIDKVRYMFNKIT"
     gene            1226..1414
                     /locus_tag="ACF3MF_003051"
     CDS             1226..1414
                     /locus_tag="ACF3MF_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HFE3928910.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(1472..1825)
                     /locus_tag="ACF3MF_003052"
     CDS             complement(1472..1825)
                     /locus_tag="ACF3MF_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3928911.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            2356..2778
                     /locus_tag="ACF3MF_003053"
     CDS             2356..2778
                     /locus_tag="ACF3MF_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFE3928912.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            2775..3005
                     /locus_tag="ACF3MF_003054"
     CDS             2775..3005
                     /locus_tag="ACF3MF_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFE3928913.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            3503..3703
                     /locus_tag="ACF3MF_003055"
     CDS             3503..3703
                     /locus_tag="ACF3MF_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000633907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HFE3928914.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            3730..>4224
                     /locus_tag="ACF3MF_003056"
     CDS             3730..>4224
                     /locus_tag="ACF3MF_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Arm DNA-binding domain-containing protein"
                     /protein_id="HFE3928915.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQK"
BASE COUNT         1433 a          679 c          790 g         1322 t
ORIGIN      
        1 cttgcatata tacgccttta tagtggagta ctacatttac gagattcggt tagagtatca
       61 gaaaaagaaa aaataaaagt tacagaaatg tatacttcaa taaatggtga attatgtaag
      121 attgatagag cttattctgg agaaattgtt attttgcaaa atgagttttt gaagttaaat
      181 agtgttcttg gagatacaaa actattgcca cagagaaaaa agattgaaaa tccgcaccct
      241 ctactacaaa caactgttga accgagtaaa cctgaacaga gagaaatgtt gcttgatgcc
      301 cttttggaaa tctcagatag tgatccgctt ctacgatatt acgtggattc tacgacacat
      361 gaaattatac tttctttctt agggaaagta caaatggaag tgattagtgc actgttgcaa
      421 gaaaagtatc atgtggagat agaactaaaa gagcctacag tcatttatat ggagagaccg
      481 ttaaaaaatg cagaatatac cattcacatc gaagtgccgc caaatccttt ctgggcttcc
      541 attggtttat ctgtatcacc gcttccgttg ggaagtggaa tgcagtatga gagctcggtt
      601 tctcttggat acttaaatca atcatttcaa aatgcagtta tggaagggat acgctatggt
      661 tgcgaacaag gattatatgg ttggaatgtg acggattgta aaatctgttt taagtacggt
      721 ttatactata gccctgttag tactccagca gattttcgga tgcttactcc tattgtactg
      781 gagcaagcct ttagaaaagc tggaacagaa ttgttagagc catatcttag ttttaaagtt
      841 tatgcaccac aggaatatct ttcacgggca tataacgatg ctcccaaata ttgtgcaaat
      901 atcgtaaata ctcaactgaa aaataatgag gtcattatta ttggagaaat tcctgctcga
      961 tgtattcaag attatcgcaa tgatttaact ttttttacaa atgggcttag tgtttgttta
     1021 gcagagctaa aaggatatca ggttaccact ggcgaacctg tttgccagac ccgtcgtcta
     1081 aatagtcgga tagataaagt aagatatatg ttcaataaaa taacttagtg cgttttatgt
     1141 tgttatataa atatggtttc ttattaaata agatgaaata ttctttaata tagatttgaa
     1201 ttaaagtgga aaggaggaga ttgttattat aaactacaag tggatattgt gtcctatttg
     1261 tggaaataaa acaagactac gaatacgagt ggatactata cttaaaaatt tccctttata
     1321 ctgccccaaa tgtaagaacg aaactttaat taatgttcaa aaaatgaata taataacaat
     1381 caaagagcca gacgccaaga cgcagagccg ataatttgag aaatgaaact ctcatcttat
     1441 cggctctttt tgtttatctg aattttactg actagccttc aatatttctt gcttcattga
     1501 taccttttgc tagtgcttcc attaaggata gttctttgtc tgtaaagcta tccatgtatt
     1561 tttctacctg taaccttcga gtgcttttaa tcaaattatc tgtaggtaag aaaaattcat
     1621 caatagatac atggagtaat gatacaagat catacagcac ttgtgtactt gggtgttgtc
     1681 ctttgttttc tatatttgtt aaataacgtg ggtcaatttc aatcattgtt cccacttgtt
     1741 cacgagtgag accccgtttc attcgagcct ctttaatcgc taaaccaacg gctctaaaat
     1801 cgtatttatc ttctttttta cgcatactaa atcacctcta tacattttac tgttcctata
     1861 taaccataaa caggtataga aaaacatgtt atatagttta tgagttccta tagaacactg
     1921 tggaatttat taatgcgatg aatccaattt caaatagaaa ggtcgctgat tttatttacc
     1981 tatacaactt tataaaattt agtcatactc ctagaaagta gataaaattg gcgacttaat
     2041 ggagggaaaa gtcgccatga gaaagataat ctgtcatcta gttctcttaa ttaagttctt
     2101 atcaaaaaaa cttatccacc tgtactggat agatatgacc atcaatgtgg ttttgcagat
     2161 tacatagata gaaaaatcaa agcatatgaa cagagaaaac aatctgttta tgtgcttttt
     2221 tggtcactta ataaatatct tttaggattt ctcttcattt atgcaacaaa tcccccgttc
     2281 gtgtcggggt ttagtatgaa gggagataaa gaagcacatg ccactccctt tcacgacaga
     2341 aagggggtga aaagcatgaa accatcttct tttcaagaaa ccatagaaaa tcagtttgac
     2401 tatatctgca aacaagttat tgaagatgaa cgaaaagatt acttcaaaca tctagacaga
     2461 ctatcagcaa aagaagtctc gttttctgat atagataact accttgtcaa ctctttttct
     2521 actgttgata cgtacgtcac tgatttccaa ctatttaaat tatttggatt aagaatcaat
     2581 gttgaaagtg atttattaag tgaagccctg cgtcatcttt cagagaaaaa acggaacatt
     2641 attttacttc attactttat ggatatgagt gatgtggaga ttgcggagtt actaaatttg
     2701 aatcgttcga ctgtttatcg tcatcgaata agtggactag ccatgattaa agaattcatg
     2761 aaggagtgta aagaatgaaa acagcttatc caagggttcc cttccccctc attgtaaagg
     2821 cgacagatgg cgacgtggaa gcaattaatc agattgttaa acattatcga gggtatacct
     2881 caaaacgttc attacgtcgc atgacagacg aatatggaaa ttctcatatg gttattgatg
     2941 aaaccctacg tggcagaatg gaaacgaaac tcatctctaa gattttatcg ttcgaaatta
     3001 aatagtccca ttttttcgtg gaagcgtgtc gaatcgtatc cacgcttccc gatttgggag
     3061 gtttgttatt ccatcaaagc atattgtgtg ttcagtaggt tttgataggc taacaagcca
     3121 aacgttcttt gacaaccaaa taaaggcaat cgaatacgtt tcggtaagaa aagagctgat
     3181 gaactaacac gccatgacct acaaaattag tgagcgattc atgttagtaa ttcgaaagta
     3241 atctttagca ggattgctgc catgactttc ttatcgtgat aatgatactc ccgtatagcc
     3301 atagtccgag cgttagaagc gtcacaggca atgggtacgg ctacatgaga accatgcaga
     3361 agtgaaattc ctgtgagctt tgctagagct gttcgattgc taagatattc ttctcttgtc
     3421 agtgtattat tataaaacta tttgatataa ttataggtga atattggagt tttcctagcc
     3481 tataattggg aaaggagtaa taatgataac ggtcacaaaa aaggatttag ttgagctagg
     3541 atatggaact tctttttcag cagacatcat aaaaaaagca aaagaattga tgattacaaa
     3601 agggcatatc tactatcaat ctcgaaagct agatagagtc cctcgtgaag ctgttgaaga
     3661 aattctagga attcggtttt caaatgaaaa caggtctgag tagtttttgc acagtaagga
     3721 gtaaaaacta tggttaaaga cccaataaaa aaagcaaaga atggaaccta ttattttcgt
     3781 gcaaatctag gttatgattc taaagggaaa aaaattcaaa aatatcgtag tggattcact
     3841 actaaaaaag aagcaagaga agaatattcg aaactgctat tgatgaaacc agaagaatta
     3901 agtgagaata aggataaaat gacgtttaaa cattatatct ttgaaatttt ccttccatgg
     3961 tataagacac aggtaaagct cagaacatat gaaaatcgct taccaactat taagaagcat
     4021 ttctcttatt ttgataaaat ggctgtttcc gatattgagc ctattgatgt gcaaaattgg
     4081 caactaaaat tatcaaagaa gtgtaagtct tcttatgtaa gagctgttca aggactattt
     4141 tcagttgcta tggatcgagc aattgtcctt gggataacca ccacaaatcc atctaagatt
     4201 attggcaatg tgaaaaagca aaag
//
LOCUS       DAXQKX010000256         4206 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.guided.121, whole genome shotgun sequence.
ACCESSION   DAXQKX010000256 DAXQKX010000000
VERSION     DAXQKX010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4206
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.guided.121"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..233
                     /locus_tag="ACF3MF_003057"
     CDS             <1..233
                     /locus_tag="ACF3MF_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HFE3928916.1"
                     /translation="NNAYCINEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECY
                     DMTEKLYKEVNEIVSEINNFLNEESSDERKQI"
     gene            214..948
                     /locus_tag="ACF3MF_003058"
     CDS             214..948
                     /locus_tag="ACF3MF_003058"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFE3928917.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            981..1844
                     /gene="ant(6)"
                     /locus_tag="ACF3MF_003059"
     CDS             981..1844
                     /gene="ant(6)"
                     /locus_tag="ACF3MF_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003109014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HFE3928918.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYPKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHLNQILRFELLRMMSWKVGIKTEFSLSVGKNYKYINKYID
                     EDLWNRLLSTYRMDSYENIWKSLFICHQLFREVSKEVAELLGFDYPEYGKNITRYTED
                     MYKKYVENDYF"
     gene            1888..2415
                     /locus_tag="ACF3MF_003060"
     CDS             1888..2415
                     /locus_tag="ACF3MF_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="HFE3928919.1"
                     /translation="MESTDVINEIRGILPRNSIGKYDLLTIFTHKTVFDKIVKVLSLD
                     FQNKVDYVAAPEAIGWILGTAIAKELGVGFIGVRKGDKLPYAKEEIISTHFTDYSGQD
                     KSFEISKSSIVRNKRVLIVDDWIETGSQMKALIALLEKLDCSIIGLATIGIDINEVTQ
                     KWIDSSFVAYIGLNI"
     gene            2643..3962
                     /locus_tag="ACF3MF_003061"
     CDS             2643..3962
                     /locus_tag="ACF3MF_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSsu5 family transposase"
                     /protein_id="HFE3928920.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGRLSSDSGLVLVKELMNTFGFSH
                     LAKQWLHITDHRAYFTHDNLAILEQLIMQLIAGYSADSSANLLRRDPVFQAVLGKKQL
                     ASQSSISRFLDRFTEENIDQLQALNQSLIDKARLIRNDTELIIDVDSTHSDTFGRQEQ
                     TDYNAHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKAFINPLLHHYKSTLPH
                     TEILVRGDSGFATPEVYESCEATESQYVIRLKSNRRLSQLAEHSVLYGDNQEWEEREV
                     QYFSLPYQAQSWSKPRRVCIRSVREGGELLFHHAFIVTNLSDNVSPEVIFSLYGKRGT
                     MENFIKEAKGGFYFDKTDSPRFLENHVRMMISVLAYNLVNFLKSIGFDKVNQGMTIHS
                     IRLILLKVAGKLVQTGRQVYLKLSSYHVYQTEFYKVFERLRRSKQWI"
BASE COUNT         1430 a          664 c          859 g         1253 t
ORIGIN      
        1 gtaataatgc ttattgcatt aacgaaaaga aagctataaa actgcttgaa acttttgaat
       61 ataaacctga aaaatatgcc gaaagagtta atcatatttt tgaagtactc ggtctttctc
      121 tttttgaatg ctacgatatg accgagaaac tttataaaga agtgaatgaa attgtatcgg
      181 agataaataa ctttttaaac gaggagagtt cagatgaaag aaaacaaata tgatgataat
      241 atattttttc aaaaatacag tcaaatgagt cgctcgcaga aaggactggc tggtgcggga
      301 gaatgggaga ctttgaaaaa gatgctacct gattttaagg gtaagcgtgt gcttgattta
      361 ggatgcggct atggatggca ctgtatatat gcgatggaaa acggtgcttc ctctgtagta
      421 ggtgttgata tttctcataa aatgctcgaa gtagcaaaag gaaaaaccca ttttccacag
      481 attgaatatg aatgctgtgc catagaagat gtggatttcc cagaggagag ctttgatgta
      541 atactaagtt cgcttgcgtt tcattatgta gcagactatg agaatttaat aaaaaagata
      601 tataggatgc tgaaggctgg tggcaattta gtttttacag ttgaacatcc tgtttttact
      661 gctcatggaa cacaagactg gtattataac gaaaaaggag aaatactgca tttcccggtg
      721 gacaattatt attatgaggg caaacggaca gctatgtttt tggaagaaaa ggttacaaaa
      781 tatcatagaa cactgaccac atatctaaat acactgcttt caaatagttt tataataaat
      841 cagattgtgg agccacagcc gccagagaac atgatggata ttccggggat ggcggatgaa
      901 atgcgacgcc caatgatgct gattgtatcg gcaaaaaaga agatgtaata atatagaaaa
      961 aataaacgag gagtatgtaa atgagatcag aaaaagaaat gatggattta gtactttctt
     1021 tagcagaaca ggatgaacgt attcgaattg tgacccttga ggggtcacgc gcaaatatta
     1081 atatacctaa agatgaattt caggattatg atattacata ttttgtaagt gatatagaac
     1141 cgtttatatc taatgatgac tggcttaatc aatttgggaa tataataatg atgcaaaagc
     1201 cggaggatat ggaattattc ccacctgaag aaaagggatt ttcctatctt atgctatttg
     1261 atgattacaa taaaattgat cttaccttat tgcccttgga agagttagat aattacccaa
     1321 agggcgataa attaataaag gttctaattg ataaagattg tagaattaaa agggacatag
     1381 ttccgactga tatagattat catgtaagaa agccaagcgc aagggagtat gatgattgct
     1441 gcaatgaatt ttggaatgta acaccttatg ttattaaagg attgtgccgc aaagagatac
     1501 tgtttgcaat cgatcatctg aaccagattc tacggtttga actacttagg atgatgtcgt
     1561 ggaaggttgg gataaagaca gaattttcat taagtgttgg gaaaaattat aagtatatta
     1621 acaaatacat tgatgaagat ctatggaata gattattatc tacatatcgc atggattcct
     1681 atgaaaatat ttggaagtca ttatttatat gccaccaatt gttcagggaa gtgtccaaag
     1741 aggtagcaga actactgggg tttgattatc cagagtatgg taagaacata acaagatata
     1801 ccgaggacat gtataaaaaa tatgttgaaa atgactattt ttaaagatta gcaaagatta
     1861 ttaaccataa gcaaggggtg taaatgtatg gaaagtactg atgttataaa tgaaattaga
     1921 ggtatattac ctcgtaactc aattggaaaa tatgatttac taactatttt tacacataaa
     1981 accgtttttg ataaaattgt aaaagtacta tcattggatt ttcaaaataa agtagattat
     2041 gtggctgccc cagaagcaat tggatggata ctaggcactg ccatagccaa agaacttgga
     2101 gtggggttta ttggagtaag aaaaggtgat aagctgccat acgcaaaaga agagattatt
     2161 tcgacacatt ttaccgacta ttcaggtcaa gataaaagct ttgaaatatc taagagttct
     2221 attgtgagga acaaaagagt tttgattgta gatgattgga tagagacagg ttctcaaatg
     2281 aaggctttaa tagctttgtt agagaaattg gattgcagca ttattgggtt ggctactatt
     2341 gggattgata taaatgaggt tactcaaaaa tggatagaca gcagttttgt agcttatatt
     2401 ggcttaaaca tataataaac cgaaagaaaa tcttgaatca aaattttgga tggcgttaat
     2461 ttacaataca acgaaagatg tttaccctga ataattcata ctttttaatt gaaaccgtct
     2521 gaaactgcct aacggcagtc tgataattac ttttttagtt tcacccctta agtgatgaaa
     2581 aaagaacccc attctgctat ggtaaaggtg acgaaaccaa ccataagaaa ggagttcttc
     2641 tcatgactag cttacacaaa aatcaagtta aattcaattc aaatatcact atttcacata
     2701 ccggtggtcg tctatcaagt gattcggggt tagtcctggt taaagaatta atgaatacct
     2761 tcggcttttc gcacttagct aaacaatggc tccatattac agatcatcgg gcttatttta
     2821 cccatgataa cttagcgata ttggaacagc ttattatgca attaattgct ggttactcgg
     2881 cagactcatc agctaatcta ttaagacggg atcctgtctt tcaagctgta ctcggtaaaa
     2941 aacagttggc atcacaatcc tcaatctcac ggtttctgga tcgtttcacc gaggagaaca
     3001 tcgatcaact ccaagcatta aatcagtcat tgattgataa agcacgttta attcgcaatg
     3061 acaccgagtt aatcattgat gtcgattcca cacattcgga tacctttgga cgccaagaac
     3121 aaacagatta taatgcccat tatcaaacct acggctatca cccattagtt gcctttgatg
     3181 gactgaccgg agatttctta aaagctgaac tgcgttcagg caatcagtac acatctaaag
     3241 gggtaaaagc ctttatcaac ccgcttttac accactacaa gagcacgtta cctcataccg
     3301 agatattggt tcggggtgac agcggcttcg ccacaccaga ggtgtatgag tcttgtgaag
     3361 caactgaaag ccagtacgtt atccgattaa agagcaatcg gaggttaagt cagttagctg
     3421 aacattctgt tctttacggg gacaatcaag aatgggaaga gcgagaagtg cagtattttt
     3481 cactacctta tcaagcacaa tcctggtcga aacctcgtcg tgtctgtata cgctccgtcc
     3541 gtgaaggagg agaattgcta tttcatcatg cgtttattgt gactaatcta tccgacaatg
     3601 tctcgcctga agtcatattt tctctttacg gcaagcgagg aacaatggaa aatttcatca
     3661 aagaagcgaa aggtggcttt tacttcgata aaacagatag cccgcgtttc ttagaaaatc
     3721 atgtcagaat gatgatcagt gtccttgcat acaacctcgt taatttttta aaaagcattg
     3781 gttttgataa agtgaaccag ggcatgacga ttcattccat ccggctgata ttgcttaaag
     3841 tagccggtaa acttgttcag actgggagac aggtctatct caaactgtca agttatcatg
     3901 tgtatcaaac tgaattttat aaggtttttg aacgcctgcg gcgatccaaa caatggattt
     3961 agactagtta tcacacaaat tttttaaccg attctttttc aagggattcg tctgccctta
     4021 aatagacaaa taatttttat tatgatcttc ttccgtaggc atcctgttcg aaaacacatt
     4081 attttggaag aaagtatctg cctaatttaa aaattggcaa tttgttcaaa aaaacaggtt
     4141 aaatttagag ctatgaatta ttcaggtttt ttcgaggtgg aagctagtat aaaagtaaac
     4201 caaggg
//
LOCUS       DAXQKX010000257         3296 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.guided.129, whole genome shotgun sequence.
ACCESSION   DAXQKX010000257 DAXQKX010000000
VERSION     DAXQKX010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3296
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.guided.129"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            22..1941
                     /gene="tet(M)"
                     /locus_tag="ACF3MF_003062"
     CDS             22..1941
                     /gene="tet(M)"
                     /locus_tag="ACF3MF_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HFE3928921.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARRIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            2039..3259
                     /gene="tet"
                     /locus_tag="ACF3MF_003063"
                     /pseudo
     CDS             2039..3259
                     /gene="tet"
                     /locus_tag="ACF3MF_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008493 - tetracycline transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015904 - tetracycline transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tet(L)/Tet(K)/Tet(45) family tetracycline efflux
                     MFS transporter"
BASE COUNT         1053 a          503 c          682 g         1058 t
ORIGIN      
        1 ttttgaatgg aggaaaatca catgaaaatt attaatattg gagttttagc tcatgttgat
       61 gcaggaaaaa ctaccttaac agaaagctta ttatataaca gtggagcgat tacagaatta
      121 ggaagcgtgg acaaaggtac aacgaggacg gataatacgc ttttagaacg tcagagagga
      181 attacaattc agacaggaat aacctctttt cagtgggaaa atacgaaggt gaacatcata
      241 gacacgccag gacatatgga tttcttagca gaagtatatc gttcattatc agttttagat
      301 ggggcaattc tactgatttc tgcaaaagat ggcgtacaag cacaaactcg tatattattt
      361 catgcactta ggaaaatggg gattcccaca atctttttta tcaataagat tgaccaaaat
      421 ggaattgatt tatcaacggt ttatcaggat attaaagaga aactttctgc cgaaattgta
      481 atcaaacaga aggtagaact gtatcctaat atgtgtgtga cgaactttac cgaatctgaa
      541 caatgggata cggtaataga gggaaacgat gaccttttag agaaatatat gtccggtaaa
      601 tcattagaag cattggaact cgaacaagag gaaagcataa gatttcagaa ttgctccttg
      661 taccctgttt atcatggaag cgcaaaaagc aacataggga ttgagcagct tatagaagtg
      721 ataacgaata aattttattc atcaacatac agaaagaagt ctgaactttg cggaaatgtc
      781 ttcaaaattg aatattcgga agaaagacaa cgtcttgcat atgtacgcct ttatggcgga
      841 atcctgcatt tgcgggattc ggttagaata tcggaaaagg aaaaaataaa aattacagaa
      901 atgtatactt caataaatgg tgaattatgt aaaattgata aggcttattc cggggaaatt
      961 gttattttgc aaaatgagtt tttgaagcta aatagtgttc ttggagatac aaagctattg
     1021 ccacagagag agagaattga aaatccgctc cctctgctgc aaacaactgt tgaaccgagc
     1081 aaacctcaac aaagggaaat gttacttgat gcacttttag aaatctccga cagtgacccg
     1141 cttctacaat attatgtgga ttctacgaca catgaaatta tactttcttt cttagggaaa
     1201 gtacaaatgg aagtgattag tgcactgttg caagaaaagt atcatgtgga gatagaacta
     1261 aaagagccta cagtcattta tatggagaga ccgttaaaaa atgcagaata taccattcac
     1321 atcgaagtgc cgccaaatcc tttctgggct tccattggtt tatctgtatc accgcttccg
     1381 ttgggaagtg gaatgcagta tgagagctcg gtttctcttg gatacttaaa tcaatcattt
     1441 caaaatgcag ttatggaagg gatacgctat ggttgcgaac aaggattata tggttggaat
     1501 gtgacggatt gtaaaatctg ttttaagtat ggcttatact atagccctgt tagtacccca
     1561 gcagattttc ggatgcttgc tcctattgta ttggaacaag tcttaaaaaa agctggaaca
     1621 gaattgttag agccatatct tagttttaaa atttatgcgc cacaggaata tctttcacga
     1681 gcatacaacg atgctcctaa atattgtgcg aacatcgtag acactcaatt gaaaaataat
     1741 gaggtcattc ttagtggaga aatccctgct cggcgtattc aagaatatcg tagtgattta
     1801 actttcttta caaatggacg tagtgtttgt ttaacagagt taaaagggta ccatgttact
     1861 accggtgaac ctgtttgcca gccccgtcgt ccaaatagtc ggatagataa agtacgatat
     1921 atgttcaata aaataactta gtgtatttta tgttgttata taaatatggt ttcttgttaa
     1981 ataagatgaa atatttttta ataaagattt gaattaaagt gtaaaggagg aattaattat
     2041 gaagtgtaat gaatgtaaca gggttaaata caaccaaatt ttaatttggc tttgcgtttt
     2101 atcttttttt agcgtattaa atgaaatggt tttgaacgtc tcattacctg atattgcaaa
     2161 tgattttaat aaaccacctg cgagtacaaa ctgggtgaac acagccttta tgttaacctt
     2221 ttccattgga acagctgtat atggaaagct atctgatcaa ttaggcatca aaaggttact
     2281 cctatttgga attataataa attgtttcgg gtcggtaatt gggtttgttg gccattcttt
     2341 cttttcctta cttattatgg ctcgttttat tcaaggggct ggtgcagctg catttccagc
     2401 actcgtaatg gttgtagttg cgcgctatat tccaaaggaa aataggggta aagcatttgg
     2461 tcttattgga tcgatagtag ccatgggaga aggagtcggt ccagcgattg gtggaatgat
     2521 agcccattat attcattggt cctatcttct actcattcct atgataacaa ttatcactgt
     2581 tccgtttctt atgaaattat taaagaaaga agtaaggata aaaggtcatt ttgatatcaa
     2641 aggaattata ctaatgtctg taggcattgt attttttatg ttgtttacaa catcatatag
     2701 catttctttt cttatcgtta gcgtgctgtc attcctgata tttgtaaaac atatcaggaa
     2761 agtaacagat ccttttgttg atcccggatt agggaaaaat atacctttta tgattggagt
     2821 tctttgtggg ggaattatat ttggaacagt agcagggttt gtctctatgg ttccttatat
     2881 gatgaaagat gttcaccagc taagtactgc cgaaatcgga agtgtaatta ttttccctgg
     2941 aacaatgagt gtcattattt tcggctacat tggtgggata cttgttgata gaagaggtcc
     3001 tttatacgtg ttaaacatcg gagttacatt tctttctgtt agctttttaa ctgcttcctt
     3061 tcttttagaa acaacatcat ggttcatgac aattataatc gtatttgttt taggtgggct
     3121 ttcgttcacc aaaacagtta tatcaacaat tgtttcaagt agcttgaaac agcaggaagc
     3181 tggtgctgga atgagtttgc ttaactttac cagcttttta tcagagggaa caggtattgc
     3241 aattgtaggt ggtttattat ggctctttgt caataaggac tgatgggttg tacaaa
//
LOCUS       DAXQKX010000258         3296 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.guided.130, whole genome shotgun sequence.
ACCESSION   DAXQKX010000258 DAXQKX010000000
VERSION     DAXQKX010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3296
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.guided.130"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            22..1941
                     /gene="tet(M)"
                     /locus_tag="ACF3MF_003064"
     CDS             22..1941
                     /gene="tet(M)"
                     /locus_tag="ACF3MF_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HFE3928922.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARRIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            2039..3259
                     /gene="tet"
                     /locus_tag="ACF3MF_003065"
                     /pseudo
     CDS             2039..3259
                     /gene="tet"
                     /locus_tag="ACF3MF_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008493 - tetracycline transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015904 - tetracycline transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tet(L)/Tet(K)/Tet(45) family tetracycline efflux
                     MFS transporter"
BASE COUNT         1052 a          503 c          683 g         1058 t
ORIGIN      
        1 ttttgaatgg aggaaaatca catgaaaatt attaatattg gagttttagc tcatgttgat
       61 gcgggaaaaa ctaccttaac agaaagctta ttatataaca gtggagcgat tacagaatta
      121 ggaagcgtgg acaaaggtac aacgaggacg gataatacgc ttttagaacg tcagagagga
      181 attacaattc agacaggaat aacctctttt cagtgggaaa atacgaaggt gaacatcata
      241 gacacgccag gacatatgga tttcttagca gaagtatatc gttcattatc agttttagat
      301 ggggcaattc tactgatttc tgcaaaagat ggcgtacaag cacaaactcg tatattattt
      361 catgcactta ggaaaatggg gattcccaca atctttttta tcaataagat tgaccaaaat
      421 ggaattgatt tatcaacggt ttatcaggat attaaagaga aactttctgc cgaaattgta
      481 atcaaacaga aggtagaact gtatcctaat atgtgtgtga cgaactttac cgaatctgaa
      541 caatgggata cggtaataga gggaaacgat gaccttttag agaaatatat gtccggtaaa
      601 tcattagaag cattggaact cgaacaagag gaaagcataa gatttcagaa ttgctccttg
      661 taccctgttt atcatggaag cgcaaaaagc aacataggga ttgagcagct tatagaagtg
      721 ataacgaata aattttattc atcaacatac agaaagaagt ctgaactttg cggaaatgtc
      781 ttcaaaattg aatattcgga agaaagacaa cgtcttgcat atgtacgcct ttatggcgga
      841 atcctgcatt tgcgggattc ggttagaata tcggaaaagg aaaaaataaa aattacagaa
      901 atgtatactt caataaatgg tgaattatgt aaaattgata aggcttattc cggggaaatt
      961 gttattttgc aaaatgagtt tttgaagcta aatagtgttc ttggagatac aaagctattg
     1021 ccacagagag agagaattga aaatccgctc cctctgctgc aaacaactgt tgaaccgagc
     1081 aaacctcaac aaagggaaat gttacttgat gcacttttag aaatctccga cagtgacccg
     1141 cttctacaat attatgtgga ttctacgaca catgaaatta tactttcttt cttagggaaa
     1201 gtacaaatgg aagtgattag tgcactgttg caagaaaagt atcatgtgga gatagaacta
     1261 aaagagccta cagtcattta tatggagaga ccgttaaaaa atgcagaata taccattcac
     1321 atcgaagtgc cgccaaatcc tttctgggct tccattggtt tatctgtatc accgcttccg
     1381 ttgggaagtg gaatgcagta tgagagctcg gtttctcttg gatacttaaa tcaatcattt
     1441 caaaatgcag ttatggaagg gatacgctat ggttgcgaac aaggattata tggttggaat
     1501 gtgacggatt gtaaaatctg ttttaagtat ggcttatact atagccctgt tagtacccca
     1561 gcagattttc ggatgcttgc tcctattgta ttggaacaag tcttaaaaaa agctggaaca
     1621 gaattgttag agccatatct tagttttaaa atttatgcgc cacaggaata tctttcacga
     1681 gcatacaacg atgctcctaa atattgtgcg aacatcgtag acactcaatt gaaaaataat
     1741 gaggtcattc ttagtggaga aatccctgct cggcgtattc aagaatatcg tagtgattta
     1801 actttcttta caaatggacg tagtgtttgt ttaacagagt taaaagggta ccatgttact
     1861 accggtgaac ctgtttgcca gccccgtcgt ccaaatagtc ggatagataa agtacgatat
     1921 atgttcaata aaataactta gtgtatttta tgttgttata taaatatggt ttcttgttaa
     1981 ataagatgaa atatttttta ataaagattt gaattaaagt gtaaaggagg aattaattat
     2041 gaagtgtaat gaatgtaaca gggttaaata caaccaaatt ttaatttggc tttgcgtttt
     2101 atcttttttt agcgtattaa atgaaatggt tttgaacgtc tcattacctg atattgcaaa
     2161 tgattttaat aaaccacctg cgagtacaaa ctgggtgaac acagccttta tgttaacctt
     2221 ttccattgga acagctgtat atggaaagct atctgatcaa ttaggcatca aaaggttact
     2281 cctatttgga attataataa attgtttcgg gtcggtaatt gggtttgttg gccattcttt
     2341 cttttcctta cttattatgg ctcgttttat tcaaggggct ggtgcagctg catttccagc
     2401 actcgtaatg gttgtagttg cgcgctatat tccaaaggaa aataggggta aagcatttgg
     2461 tcttattgga tcgatagtag ccatgggaga aggagtcggt ccagcgattg gtggaatgat
     2521 agcccattat attcattggt cctatcttct actcattcct atgataacaa ttatcactgt
     2581 tccgtttctt atgaaattat taaagaaaga agtaaggata aaaggtcatt ttgatatcaa
     2641 aggaattata ctaatgtctg taggcattgt attttttatg ttgtttacaa catcatatag
     2701 catttctttt cttatcgtta gcgtgctgtc attcctgata tttgtaaaac atatcaggaa
     2761 agtaacagat ccttttgttg atcccggatt agggaaaaat atacctttta tgattggagt
     2821 tctttgtggg ggaattatat ttggaacagt agcagggttt gtctctatgg ttccttatat
     2881 gatgaaagat gttcaccagc taagtactgc cgaaatcgga agtgtaatta ttttccctgg
     2941 aacaatgagt gtcattattt tcggctacat tggtgggata cttgttgata gaagaggtcc
     3001 tttatacgtg ttaaacatcg gagttacatt tctttctgtt agctttttaa ctgcttcctt
     3061 tcttttagaa acaacatcat ggttcatgac aattataatc gtatttgttt taggtgggct
     3121 ttcgttcacc aaaacagtta tatcaacaat tgtttcaagt agcttgaaac agcaggaagc
     3181 tggtgctgga atgagtttgc ttaactttac cagcttttta tcagagggaa caggtattgc
     3241 aattgtaggt ggtttattat ggctctttgt caataaggac tgatgggttg tacaaa
//
LOCUS       DAXQKX010000259         2483 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.guided.144, whole genome shotgun sequence.
ACCESSION   DAXQKX010000259 DAXQKX010000000
VERSION     DAXQKX010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2483
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.guided.144"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..1128
                     /locus_tag="ACF3MF_003066"
     CDS             <1..1128
                     /locus_tag="ACF3MF_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein"
                     /protein_id="HFE3928923.1"
                     /translation="LAYIRLYSGVLHLRDSVRVSEKEKIKVTEMYTSINGELCKIDRA
                     YSGEIVILQNEFLKLNSVLGDTKLLPQRKKIENPHPLLQTTVEPSKPEQREMLLDALL
                     EISDSDPLLRYYVDSTTHEIILSFLGKVQMEVISALLQEKYHVEIELKEPTVIYMERP
                     LKNAEYTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSFQNAVMEGIR
                     YGCEQGLYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPYL
                     SFKIYAPQEYLSRAYNDAPKYCANIVDTQLKNNEVILSGEIPARRIQEYRSDLTFFTN
                     GRSVCLTELKGYHVTTGEPVCQPRRPNSRIDKVRYMFNKIT"
     gene            1226..2446
                     /gene="tet"
                     /locus_tag="ACF3MF_003067"
                     /pseudo
     CDS             1226..2446
                     /gene="tet"
                     /locus_tag="ACF3MF_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008493 - tetracycline transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015904 - tetracycline transmembrane
                     transport [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tet(L)/Tet(K)/Tet(45) family tetracycline efflux
                     MFS transporter"
BASE COUNT          760 a          375 c          507 g          841 t
ORIGIN      
        1 cttgcatata tacgccttta tagtggagta ctacatttac gagattcggt tagagtatca
       61 gaaaaagaaa aaataaaagt tacagaaatg tatacttcaa taaatggtga attatgtaag
      121 attgatagag cttattctgg agaaattgtt attttgcaaa atgagttttt gaagttaaat
      181 agtgttcttg gagatacaaa actattgcca cagagaaaaa agattgaaaa tccgcaccct
      241 ctactacaaa caactgttga accgagtaaa cctgaacaga gagaaatgtt gcttgatgcc
      301 cttttggaaa tctcagatag tgatccgctt ctacgatatt acgtggattc tacgacacat
      361 gaaattatac tttctttctt agggaaagta caaatggaag tgattagtgc actgttgcaa
      421 gaaaagtatc atgtggagat agaactaaaa gagcctacag tcatttatat ggagagaccg
      481 ttaaaaaatg cagaatatac cattcacatc gaagtgccgc caaatccttt ctgggcttcc
      541 attggtttat ctgtatcacc gcttccgttg ggaagtggaa tgcagtatga gagctcggtt
      601 tctcttggat acttaaatca atcatttcaa aatgcagtta tggaagggat acgctatggt
      661 tgcgaacaag gattatatgg ttggaatgtg acggattgta aaatctgttt taagtatggc
      721 ttatactata gccctgttag taccccagca gattttcgga tgcttgctcc tattgtattg
      781 gaacaagtct taaaaaaagc tggaacagaa ttgttagagc catatcttag ttttaaaatt
      841 tatgcgccac aggaatatct ttcacgagca tacaacgatg ctcctaaata ttgtgcgaac
      901 atcgtagaca ctcaattgaa aaataatgag gtcattctta gtggagaaat ccctgctcgg
      961 cgtattcaag aatatcgtag tgatttaact ttctttacaa atggacgtag tgtttgttta
     1021 acagagttaa aagggtacca tgttactacc ggtgaacctg tttgccagcc ccgtcgtcca
     1081 aatagtcgga tagataaagt acgatatatg ttcaataaaa taacttagtg tattttatgt
     1141 tgttatataa atatggtttc ttgttaaata agatgaaata ttttttaata aagatttgaa
     1201 ttaaagtgta aaggaggaat taattatgaa gtgtaatgaa tgtaacaggg ttaaatacaa
     1261 ccaaatttta atttggcttt gcgttttatc tttttttagc gtattaaatg aaatggtttt
     1321 gaacgtctca ttacctgata ttgcaaatga ttttaataaa ccacctgcga gtacaaactg
     1381 ggtgaacaca gcctttatgt taaccttttc cattggaaca gctgtatatg gaaagctatc
     1441 tgatcaatta ggcatcaaaa ggttactcct atttggaatt ataataaatt gtttcgggtc
     1501 ggtaattggg tttgttggcc attctttctt ttccttactt attatggctc gttttattca
     1561 aggggctggt gcagctgcat ttccagcact cgtaatggtt gtagttgcgc gctatattcc
     1621 aaaggaaaat aggggtaaag catttggtct tattggatcg atagtagcca tgggagaagg
     1681 agtcggtcca gcgattggtg gaatgatagc ccattatatt cattggtcct atcttctact
     1741 cattcctatg ataacaatta tcactgttcc gtttcttatg aaattattaa agaaagaagt
     1801 aaggataaaa ggtcattttg atatcaaagg aattatacta atgtctgtag gcattgtatt
     1861 ttttatgttg tttacaacat catatagcat ttcttttctt atcgttagcg tgctgtcatt
     1921 cctgatattt gtaaaacata tcaggaaagt aacagatcct tttgttgatc ccggattagg
     1981 gaaaaatata ccttttatga ttggagttct ttgtggggga attatatttg gaacagtagc
     2041 agggtttgtc tctatggttc cttatatgat gaaagatgtt caccagctaa gtactgccga
     2101 aatcggaagt gtaattattt tccctggaac aatgagtgtc attattttcg gctacattgg
     2161 tgggatactt gttgatagaa gaggtccttt atacgtgtta aacatcggag ttacatttct
     2221 ttctgttagc tttttaactg cttcctttct tttagaaaca acatcatggt tcatgacaat
     2281 tataatcgta tttgttttag gtgggctttc gttcaccaaa acagttatat caacaattgt
     2341 ttcaagtagc ttgaaacagc aggaagctgg tgctggaatg agtttgctta actttaccag
     2401 ctttttatca gagggaacag gtattgcaat tgtaggtggt ttattatggc tctttgtcaa
     2461 taaggactga tgggttgtac aaa
//
LOCUS       DAXQKX010000260         1998 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.guided.152, whole genome shotgun sequence.
ACCESSION   DAXQKX010000260 DAXQKX010000000
VERSION     DAXQKX010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1998
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.guided.152"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            47..439
                     /locus_tag="ACF3MF_003068"
     CDS             47..439
                     /locus_tag="ACF3MF_003068"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFE3928924.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDDIVYVYDYEKGDK"
     gene            440..1879
                     /locus_tag="ACF3MF_003069"
                     /note="aph(2'')-Ia"
     CDS             440..1879
                     /locus_tag="ACF3MF_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HFE3928925.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYDGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTDKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCSHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT          829 a          153 c          344 g          672 t
ORIGIN      
        1 aacattgtat agcattttac acaggagtct ggacttgact gagtttatgg aagaagtttt
       61 aattgatgat aatatggttt ttgatattga taatttaaaa ggatttctta atgataccag
      121 ttcatttggg tttatagcta aagaaaataa taaaattata ggatttgcat attgctatac
      181 acttttaaga cctgatggaa aaacaatgtt ttatttacac tcaataggaa tgttacctaa
      241 ctatcaagac aaaggttatg gttcaaaatt attatctttt attaaggaat attctaaaga
      301 gattggttgt tctgaaatgt ttttaataac tgataaaggt aatcctagag cttgccatgt
      361 atatgaaaaa ttaggtggta aaaatgatta taaagatgat atagtatatg tatatgatta
      421 tgaaaaaggt gataaataaa tgaatatagt tgaaaatgaa atatgtataa gaactttaat
      481 agatgatgat tttcctttga tgttaaaatg gttaactgat gaaagagtat tagaatttta
      541 tgatggtaga gataaaaaat atacattaga atcattaaaa aaacattata cagagccttg
      601 ggaagatgaa gtttttagag taattattga atataacaat gttcctattg gatatggaca
      661 aatatataaa atgtatgatg agttatatac tgattatcat tatccaaaaa ctgatgagat
      721 agtctatggt atggatcaat ttataggaga gccaaattat tggagtaaag gaattggtac
      781 aagatatatt aaattgattt ttgaattttt gaaaaaagaa agaaatgcta atgcagttat
      841 tttagaccct cataaaaata atccaagagc aataagggca taccaaaaat ctggttttag
      901 aattattgaa gatttgccag aacatgaatt acacgagggc aaaaaagaag attgttattt
      961 aatggaatat agatatgatg ataatgccac aaatgttaag gcaatgaaat atttaattga
     1021 gcattacttt gataatttca aagtagatag tattgaaata atcggtagtg gttatgatag
     1081 tgtggcatat ttagttaata atgaatacat ttttaaaaca aaatttagta ctgataagaa
     1141 aaaaggttat gcaaaagaaa aagcaatata taatttttta aatacaaatt tagaaactaa
     1201 tgtaaaaatt cctaatattg aatattcgta tattagtgat gaattatcta tactaggtta
     1261 taaagaaatt aaaggaactt ttttaacacc agaaatttat tctactatgt cagaagaaga
     1321 acaaaatttg ttaaaacgag atattgccag ttttttaaga caaatgcacg gtttagatta
     1381 tacagatatt agtgaatgta ctattgataa taaacaaaat gtattagaag agtatatatt
     1441 gttgcgtgaa actatttata atgatttaac tgatatagaa aaagattata tagaaagttt
     1501 tatggaaaga ctaaatgcaa caacagtttt tgagggtaaa aagtgtttat gccataatga
     1561 ttttagttgt agtcatctat tgttagatgg caataataga ttaactggaa taattgattt
     1621 tggagattct ggaattatag atgaatattg tgattttata tacttacttg aagatagtga
     1681 agaagaaata ggaacaaatt ttggagaaga tatattaaga atgtatggaa atatagatat
     1741 tgagaaagca aaagaatatc aagatatagt tgaagaatat tatcctattg aaactattgt
     1801 ttatggaatt aaaaatatta aacaggaatt tatcgaaaat ggtagaaaag aaatttataa
     1861 aaggacttat aaagattgat tatataatat atgaaaagct attataaaag acattagtat
     1921 taaatagttt aaaaaaatga aaaataataa aggaagtgag tcaagtccag actcctgtgt
     1981 aaaatgctat acaatgtt
//
LOCUS       DAXQKX010000261          958 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.guided.192, whole genome shotgun sequence.
ACCESSION   DAXQKX010000261 DAXQKX010000000
VERSION     DAXQKX010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..958
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.guided.192"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            345..893
                     /gene="aac(6')"
                     /locus_tag="ACF3MF_003070"
     CDS             345..893
                     /gene="aac(6')"
                     /locus_tag="ACF3MF_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HFE3928926.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          340 a          138 c          191 g          289 t
ORIGIN      
        1 agtatttcta ccgattccct ttgctttttt gtaattatct aaaaattcta aaaattaaga
       61 ttattatatg aaaacaggtt ttatttgtca attcataatt ggtttttttt aaagcaaaag
      121 ataatctata tcatgatgaa caaacagagt tttttcctcc aattgatggc tttcctgatc
      181 tttcctattt tgaataaagt gtttctgtat aattttttta ttttataagt aagataaata
      241 atgaaagaat agagatactg attggtagct aaagattttt gagcgagaac atttcgtttt
      301 ttcaaaagga ctgttagaat aagcaagaac aagggggaag acgtatgata atcagtgaat
      361 ttgaccgtaa taatccagta ttgaaagatc agctttctga tttactgaga ctgacttggc
      421 cggaagaata tggagacagc tcggcagaag aagtagaaga aatgatgaat ccagaacgaa
      481 tcgcggtagc agcggtagac caagatgagt tagtaggatt tattggtgca atccctcaat
      541 acggtatcac aggttgggaa ttgcatccat tagttgtaga aagctcccga cgaaagaacc
      601 aaataggtac tcgattagtc aattacttag aaaaagaagt agcttccaga ggaggaatca
      661 cgatttattt aggtacggat gatttagacc atggaacaac gttaagtcaa acggacctgt
      721 atgagcatac atttgataaa gtggcttcca tccagaacct tcgtgaacat ccgtatgaat
      781 tctatgaaaa attaggttat aaaatcgtag gtgtcttacc aaatgcaaat ggctgggaca
      841 aaccggatat ttggatggca aaaacgatta ttcctcgacc aaattctcaa taataaaaag
      901 aggttgtgac agaagtaatc agcttcaaga aataagaagg aatttacgaa aattactt
//
LOCUS       DAXQKX010000262          798 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.guided.202, whole genome shotgun sequence.
ACCESSION   DAXQKX010000262 DAXQKX010000000
VERSION     DAXQKX010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..798
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.guided.202"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            44..781
                     /gene="erm(B)"
                     /locus_tag="ACF3MF_003071"
     CDS             44..781
                     /gene="erm(B)"
                     /locus_tag="ACF3MF_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HFE3928927.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
BASE COUNT          293 a          139 c          125 g          241 t
ORIGIN      
        1 ttctgtattt gtttatagat gtaatcactt caggagtgat aacatgaaca aaaatataaa
       61 atattctcaa aactttttaa cgagtgaaaa agtactcaac caaataataa aacaattgaa
      121 tttaaaagaa accgataccg tttacgaaat tggaacaggt aaagggcatt taacgacgaa
      181 actggctaaa ataagtaaac aggtaacgtc tattgaatta gacagtcatc tattcaactt
      241 atcgtcagaa aaattaaaac tgaatactcg tgtcacttta attcaccaag atattctaca
      301 gtttcaattc cctaacaaac agaggtataa aattgttggg aatattcctt accatttaag
      361 cacacaaatt attaaaaaag tggtttttga aagccgtgcg tctgacatct atctgattgt
      421 tgaagaagga ttctacaagc gtaccttgga tattcaccga acactagggt tgctcttgca
      481 cactcaagtc tcgattcagc aattgcttaa gctgccagcg gaatgctttc atcctaaacc
      541 aaaagtaaac agtgtcttaa taaaacttac ccgccatacc acagatgttc cagataaata
      601 ttggaagcta tatacgtact ttgtttcaaa atgggtcaat cgagaatatc gtcaactgtt
      661 tactaaaaat cagtttcatc aagcaatgaa acacgccaaa gtaaacaatt taagtaccgt
      721 tacttatgag caagtattgt ctatttttaa tagttatcta ttatttaacg ggaggaaata
      781 attctatgag tcgctttt
//
LOCUS       DAXQKX010000263          703 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.guided.216, whole genome shotgun sequence.
ACCESSION   DAXQKX010000263 DAXQKX010000000
VERSION     DAXQKX010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..703
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.guided.216"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..696
                     /gene="erm"
                     /locus_tag="ACF3MF_003072"
     CDS             <1..696
                     /gene="erm"
                     /locus_tag="ACF3MF_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011276921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S ribosomal RNA methyltransferase Erm"
                     /protein_id="HFE3928928.1"
                     /translation="KGFYSLFKTLQQNPNDNIIEIGSGKGHFTFELAKRCNYVTAIEI
                     DPKLCRITKNKLIEYENFQVINKDILQFKFPKNKSYKIYGNIPYNISTDIIRKIVFES
                     TATESYLIVEYGFAKRLLNTNRSLALFLMTEVDISILSKIPREYFHPKPRVNSSLIVL
                     KRHPSKISLKDRKQYENFVMKWVNKEYIKLFSKNQFYQALKYARIDDLNNISFEQFLS
                     LFNRFCCKVLNKE"
BASE COUNT          287 a           94 c           95 g          227 t
ORIGIN      
        1 aagggatttt attctttatt taaaactttg caacagaacc caaatgataa tattattgag
       61 attggttcag ggaaaggtca tttcacgttt gaattagcta aaaggtgtaa ttatgtaacc
      121 gccattgaaa tagatcctaa attatgtagg ataactaaaa acaaacttat tgaatatgag
      181 aacttccagg ttatcaataa agatatttta caatttaagt ttcctaaaaa taagtcatat
      241 aagatatatg gaaatatacc ctacaatata agtacagata taattcgaaa aattgttttt
      301 gaaagcacag ctacagaaag ttatttaata gtggaatatg gatttgctaa aaggttgcta
      361 aatacaaatc gttcactagc actattttta atgacagaag ttgatatatc catattaagt
      421 aaaatcccta gagaatactt tcatccaaaa cctagagtta atagctcgtt aattgtatta
      481 aaaagacacc cttcaaaaat atcactcaaa gatagaaaac aatatgaaaa ttttgttatg
      541 aaatgggtta acaaagaata cataaaacta ttttccaaaa accaatttta tcaagcctta
      601 aaatatgcaa gaattgacga tttaaacaat attagctttg aacaattctt gtctcttttc
      661 aataggttct gttgcaaagt tttaaataaa gaataaaatc cct
//
LOCUS       DAXQKX010000264          654 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.guided.219, whole genome shotgun sequence.
ACCESSION   DAXQKX010000264 DAXQKX010000000
VERSION     DAXQKX010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..654
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.guided.219"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            117..614
                     /gene="dfrG"
                     /locus_tag="ACF3MF_003073"
     CDS             117..614
                     /gene="dfrG"
                     /locus_tag="ACF3MF_003073"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HFE3928929.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
BASE COUNT          255 a           67 c          138 g          194 t
ORIGIN      
        1 taatataact tatagaaaaa attgcttatt caactaacgg gcaggataat gagaaaaggt
       61 tttttgatag aaataagaaa ttagatggta aattagttaa aaaggctgtg ttataaatga
      121 aagtttcttt gattgctgcg atggataaga atagagtgat tggcaaagag aatgacattc
      181 cttggaggat tcccaaggac tgggaatatg ttaaaaatac tacaaaggga catccgataa
      241 tattaggtag gaagaacctt gaatcaatcg gaagagcctt acctgacaga agaaatatta
      301 ttctgacgag agataagggg tttaccttta atggttgtga aattgttcat tcaatagaag
      361 atgtttttga gttatgtaaa aacgaagaag aaatttttat tttcggagga gaacagattt
      421 ataatttgtt tttcccttat gttgagaaaa tgtacatcac aaaaatacat catgaattcg
      481 aaggagatac tttttttcca gaagtgaatt atgaggaatg gaatgaggta tttgcccaaa
      541 aagggataaa gaatgataaa aatccgtata actactattt tcatgtatat gaaagaaaaa
      601 acttattgag ttaacgggtg cgttaattga agaagaacag taaagataaa gcac
//
LOCUS       DAXQKX010000265          635 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.guided.220, whole genome shotgun sequence.
ACCESSION   DAXQKX010000265 DAXQKX010000000
VERSION     DAXQKX010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..635
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.guided.220"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            72..421
                     /locus_tag="ACF3MF_003074"
                     /pseudo
     CDS             72..421
                     /locus_tag="ACF3MF_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
BASE COUNT          210 a          115 c          100 g          210 t
ORIGIN      
        1 tcctaataga gtataacata gctttaagca ttacttaaag ataacttaaa agttatcttt
       61 taaatactta attgttaaat accttatttg atgcaaaaga aatctacgat agtcaacaaa
      121 aaaattttca ttatatccag aaaaattttt cttagttaag gacctatgga ttgcagtaat
      181 gcagaattcg tcgaataaac tgccaaagac atacaatcat attgctttta aaattgacga
      241 acaagatata gattcgtttg tctcaaaaat ccaaatgtta ggtttaactg tcgaaccagg
      301 acgttctcgt gtgaaaggcg aggcttcttc aatttacttt tacgactatg ataatcacct
      361 cttcgagtta cataccggta ctctccagga acgtttaaaa tcctacaatt ccactacctg
      421 agactagtaa tgactagtct ctttttatgg cctctgatcc ccccattgag cgaatactaa
      481 tagggcttcg aattgatctg ttcaatcttt aagcaatatc cctcaaatga gtttggaaag
      541 tttagtgatt catcacaaat acttaaatac atgtagttat atatagattg aggttcttgt
      601 gagcgtatgc tcgtgtgggt tcaaatccca tcgtc
//
LOCUS       DAXQKX010000266          457 bp    DNA     linear   BCT 09-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium strain JARB-OU2591
            SAMD00565649-rid20743473.guided.242, whole genome shotgun sequence.
ACCESSION   DAXQKX010000266 DAXQKX010000000
VERSION     DAXQKX010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMD00565649
            Sequence Read Archive: DRR428035
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 16-JAN-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002054674.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002054674.1
            Genome Coverage       :: 84x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/08/2024 13:51:16
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,075
            CDSs (total)                      :: 3,004
            Genes (coding)                    :: 2,890
            CDSs (with protein)               :: 2,890
            Genes (RNA)                       :: 71
            rRNAs                             :: 1, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 5, 5 (16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 114
            CDSs (without protein)            :: 114
            Pseudo Genes (ambiguous residues) :: 0 of 114
            Pseudo Genes (frameshifted)       :: 48 of 114
            Pseudo Genes (incomplete)         :: 66 of 114
            Pseudo Genes (internal stop)      :: 29 of 114
            Pseudo Genes (multiple problems)  :: 22 of 114
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..457
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMD00565649-rid20743473.guided.242"
                     /strain="JARB-OU2591"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Japan: Hiroshima"
                     /collection_date="2021-07-15"
                     /collected_by="Hiroshima"
     gene            <1..440
                     /locus_tag="ACF3MF_003075"
     CDS             <1..440
                     /locus_tag="ACF3MF_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="rRNA adenine N-6-methyltransferase family
                     protein"
                     /protein_id="HFE3928930.1"
                     /translation="WPFYFYTIIRTLSVFESHASDIYLIVEEGFYKRTLDIHRTLGLL
                     LHTQVSIQQLLKLPAECFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREY
                     RQLFTKNQFHQAMKYAKVNDLSTVTYEQVLSIFNSYLLFNGRK"
BASE COUNT          144 a           87 c           77 g          149 t
ORIGIN      
        1 tatggccttt ttacttttac acaattatac ggactttatc ggtttttgaa agccatgcgt
       61 ctgacatcta tctgattgtt gaagaaggat tctacaagcg taccttggat attcaccgaa
      121 cactagggtt gctcttgcac actcaagtct cgattcagca attgcttaag ctgccagcgg
      181 aatgctttca tcctaaacca aaagtaaaca gtgtcttaat aaaacttacc cgccatacca
      241 cagatgttcc agataaatat tggaagctat atacgtactt tgtttcaaaa tgggtcaatc
      301 gagaatatcg tcaactgttt actaaaaatc agtttcatca agcaatgaaa tacgccaaag
      361 taaacgattt aagtaccgtt acttatgagc aagtattgtc tatttttaat agttatctat
      421 tatttaacgg gaggaaataa ttctatgagt cgctttt
//
